geneID ACR-140 ACR-145 ACR-150 ACR-173 ACR-178 V1 V3 V13 Protein.names Organism Gene.Ontology..biological.process. Gene.Ontology.IDs 1 FUN_035039 553 340 256 485 510 NA NA NA NA NA NA NA 2 FUN_035038 2486 775 743 1250 1092 NA NA NA NA NA NA NA 3 FUN_035031 46 6 25 41 29 NA NA NA NA NA NA NA 4 FUN_035030 183 252 48 78 73 ptg000025l:3084856-3086902 A0A2B4RNI3 2.04e-25 NA NA NA NA 5 FUN_035033 1519 311 555 990 370 NA NA NA NA NA NA NA 6 FUN_035032 1764 1297 1035 1763 1360 NA NA NA NA NA NA NA 7 FUN_035035 601 256 231 521 126 NA NA NA NA NA NA NA 8 FUN_035034 3644 3770 3137 3225 3322 NA NA NA NA NA NA NA 9 FUN_035037 5546 4928 3061 4720 3018 NA NA NA NA NA NA NA 10 FUN_035036 1224 301 511 677 841 NA NA NA NA NA NA NA 11 FUN_028149 7364 4643 3472 6112 6583 ptg000021l:16233476-16243513 Q0MQG3 2.73e-21 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (EC 7.1.1.2) (Complex I-49kD) (CI-49kD) (NADH-ubiquinone oxidoreductase 49 kDa subunit) Pongo pygmaeus (Bornean orangutan) cellular response to oxygen levels [GO:0071453]; gliogenesis [GO:0042063]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neural precursor cell proliferation [GO:0061351]; neurogenesis [GO:0022008]; response to oxidative stress [GO:0006979] GO:0005739; GO:0005743; GO:0005747; GO:0006120; GO:0006979; GO:0008137; GO:0019826; GO:0022008; GO:0032981; GO:0042063; GO:0046872; GO:0048038; GO:0051287; GO:0051539; GO:0061351; GO:0071453 12 FUN_028148 2111 1690 1197 2402 2199 NA NA NA NA NA NA NA 13 FUN_028143 2378 2022 1371 1993 2292 ptg000021l:16163649-16169296 Q5SZT7 4e-25 NKAP-like protein Mus musculus (Mouse) cell differentiation [GO:0030154]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0003682; GO:0005634; GO:0007283; GO:0010468; GO:0030154 14 FUN_028143 2378 2022 1371 1993 2292 ptg000021l:16163649-16169296 Q5SZT7 4e-25 NKAP-like protein Mus musculus (Mouse) cell differentiation [GO:0030154]; regulation of gene expression [GO:0010468]; spermatogenesis [GO:0007283] GO:0003682; GO:0005634; GO:0007283; GO:0010468; GO:0030154 15 FUN_003344 0 0 10 0 0 NA NA NA NA NA NA NA 16 FUN_028147 11 0 4 0 0 NA NA NA NA NA NA NA 17 FUN_028146 0 0 7 0 25 NA NA NA NA NA NA NA 18 FUN_003340 50 2 51 3 286 ntLink_8:9018827-9021030 Q9U7D0 1.72e-45 Histone H4 Mastigamoeba balamuthi (Phreatamoeba balamuthi) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19 FUN_028144 1194 472 503 644 814 NA NA NA NA NA NA NA 20 FUN_008019 531 522 383 187 546 NA NA NA NA NA NA NA 21 FUN_013332 48 12 18 56 44 NA NA NA NA NA NA NA 22 FUN_041253 0 0 0 3 13 NA NA NA NA NA NA NA 23 FUN_013331 1235 672 591 707 520 NA NA NA NA NA NA NA 24 FUN_013336 0 0 0 0 71 ptg000008l:21227846-21230202 Q9NBX4 9.21e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25 FUN_013337 400 254 259 506 318 ptg000008l:21231533-21254739 Q95SX7 5.49e-28 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26 FUN_041254 297 116 53 368 73 NA NA NA NA NA NA NA 27 FUN_013335 31 0 0 7 6 NA NA NA NA NA NA NA 28 FUN_009376 234 91 119 228 264 NA NA NA NA NA NA NA 29 FUN_010827 1170 866 643 1289 1082 ptg000007l:3284932-3304784 Q5ZKU4 5.84e-26 Integrator complex subunit 2 (Int2) Gallus gallus (Chicken) snRNA 3'-end processing [GO:0034472] GO:0031965; GO:0032039; GO:0034472 30 FUN_010827 1170 866 643 1289 1082 ptg000007l:3284932-3304784 Q5ZKU4 1.77e-23 Integrator complex subunit 2 (Int2) Gallus gallus (Chicken) snRNA 3'-end processing [GO:0034472] GO:0031965; GO:0032039; GO:0034472 31 FUN_010826 180 134 177 14 52 NA NA NA NA NA NA NA 32 FUN_010825 2582 6423 3759 3870 2655 NA NA NA NA NA NA NA 33 FUN_010824 35 0 100 0 102 NA NA NA NA NA NA NA 34 FUN_010822 0 0 0 11 7 NA NA NA NA NA NA NA 35 FUN_010821 61 10 2 94 25 NA NA NA NA NA NA NA 36 FUN_010820 0 0 0 11 16 NA NA NA NA NA NA NA 37 FUN_032950 38 0 51 97 236 NA NA NA NA NA NA NA 38 FUN_010829 574 410 316 665 336 NA NA NA NA NA NA NA 39 FUN_010828 2745 1216 1505 3110 2503 ptg000007l:3309406-3314790 Q8YTC2 1.01e-27 Uncharacterized WD repeat-containing protein alr2800 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA GO:0043531 40 FUN_010828 2745 1216 1505 3110 2503 ptg000007l:3309406-3314790 Q8YTC2 1.03e-25 Uncharacterized WD repeat-containing protein alr2800 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA GO:0043531 41 FUN_010828 2745 1216 1505 3110 2503 ptg000007l:3309406-3314790 Q8YTC2 2.15e-22 Uncharacterized WD repeat-containing protein alr2800 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA GO:0043531 42 FUN_010828 2745 1216 1505 3110 2503 ptg000007l:3309406-3314790 Q8YTC2 6.81e-22 Uncharacterized WD repeat-containing protein alr2800 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA GO:0043531 43 FUN_010828 2745 1216 1505 3110 2503 ptg000007l:3309406-3314790 Q8YTC2 3.61e-21 Uncharacterized WD repeat-containing protein alr2800 Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) NA GO:0043531 44 FUN_003969 147 104 116 354 388 NA NA NA NA NA NA NA 45 FUN_003962 28 0 0 0 5 NA NA NA NA NA NA NA 46 FUN_003963 31 11 12 0 48 NA NA NA NA NA NA NA 47 FUN_003966 17 0 11 7 47 NA NA NA NA NA NA NA 48 FUN_003967 0 3 0 0 10 NA NA NA NA NA NA NA 49 FUN_003965 0 0 19 0 0 NA NA NA NA NA NA NA 50 FUN_028142 718 427 248 324 577 NA NA NA NA NA NA NA 51 FUN_028141 2858 6198 1145 5576 2600 NA NA NA NA NA NA NA 52 FUN_028140 2383 3283 1041 2951 1374 NA NA NA NA NA NA NA 53 FUN_009069 28 459 236 12 399 NA NA NA NA NA NA NA 54 FUN_009068 387 45 47 355 199 NA NA NA NA NA NA NA 55 FUN_009065 0 0 0 0 15 NA NA NA NA NA NA NA 56 FUN_003342 8 0 5 0 50 NA NA NA NA NA NA NA 57 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 1.22e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 58 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 1.22e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 59 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 7.81e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 60 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 2.49e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 61 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 3.16e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 62 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 7.67e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 63 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 6.7e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 64 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 3.54e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 65 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 2.28e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 66 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 7.26e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 67 FUN_009067 21 32 32 2 19 ptg000004l:2325745-2328419 Q96AY4 2.21e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 68 FUN_009061 105 248 114 39 94 ptg000004l:2272203-2278099 Q96AY4 8.06e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 69 FUN_009061 105 248 114 39 94 ptg000004l:2272203-2278099 Q96AY4 5.63e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 70 FUN_009061 105 248 114 39 94 ptg000004l:2272203-2278099 Q96AY4 1.41e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 71 FUN_009061 105 248 114 39 94 ptg000004l:2272203-2278099 Q96AY4 1.04e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 72 FUN_009061 105 248 114 39 94 ptg000004l:2272203-2278099 Q96AY4 7.57e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 73 FUN_009061 105 248 114 39 94 ptg000004l:2272203-2278099 Q96AY4 9.45e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 74 FUN_009060 22 0 0 0 0 NA NA NA NA NA NA NA 75 FUN_009063 40 0 34 0 26 NA NA NA NA NA NA NA 76 FUN_028145 4870 4938 2486 4910 3597 NA NA NA NA NA NA NA 77 FUN_003341 8 0 0 1 30 NA NA NA NA NA NA NA 78 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 79 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 7.09e-175 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 80 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 7.94e-175 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 81 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 3.06e-144 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 82 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 4.29e-116 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 83 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 7.87e-116 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 84 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 2.27e-115 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 85 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 2.37e-113 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 86 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 2.85e-99 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 87 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 1.3e-81 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 88 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 4.19e-80 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 89 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 2.9e-79 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 90 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 1.17e-27 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 91 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 1.68e-27 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 92 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 7.82e-27 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 93 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 9.26e-27 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 94 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 7.54e-26 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 95 FUN_022170 4802 2165 1524 3928 2822 ptg000016l:5864166-5945619 B8UU78 1.24e-25 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 96 FUN_022171 7 4 0 4 38 NA NA NA NA NA NA NA 97 FUN_022172 778 1520 308 388 468 NA NA NA NA NA NA NA 98 FUN_022173 31 45 29 51 91 NA NA NA NA NA NA NA 99 FUN_022174 76 144 59 67 113 ptg000016l:5968509-5971117 O42370 2.93e-23 Homeobox protein Hox-D3a (Hox-D3) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; embryonic skeletal system morphogenesis [GO:0048704]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009952; GO:0048704 100 FUN_022175 175 21 123 190 42 NA NA NA NA NA NA NA 101 FUN_022176 31 82 33 153 13 NA NA NA NA NA NA NA 102 FUN_022177 0 46 14 11 51 NA NA NA NA NA NA NA 103 FUN_022178 58 12 80 74 131 ptg000016l:6014001-6014952 P09019 2.98e-24 Homeobox protein Hox-B5 (Xhox-1B) (XlHbox-4) Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 104 FUN_022179 142 154 64 138 114 ptg000016l:6030094-6031326 P22574 6.18e-25 Homeobox protein Hox-B4a (Hox-B4) (Homeobox protein Zf-13) Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; embryonic skeletal system morphogenesis [GO:0048704]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009952; GO:0048704 105 FUN_040614 10 71 115 118 24 NA NA NA NA NA NA NA 106 FUN_040616 3635 3540 2320 3449 2259 NA NA NA NA NA NA NA 107 FUN_040610 285 230 363 424 365 NA NA NA NA NA NA NA 108 FUN_011886 12 52 29 0 40 NA NA NA NA NA NA NA 109 FUN_011887 912 0 255 960 410 ptg000008l:2495041-2499534 O34363 6.55e-27 Putative L-amino-acid oxidase YobN (EC 1.4.3.2) Bacillus subtilis (strain 168) amino acid catabolic process [GO:0009063] GO:0001716; GO:0009063; GO:0016491; GO:0046592 110 FUN_011884 1130 1011 743 1361 1621 NA NA NA NA NA NA NA 111 FUN_011885 0 0 1 0 35 NA NA NA NA NA NA NA 112 FUN_011882 3441 4049 2727 2958 1912 NA NA NA NA NA NA NA 113 FUN_011883 425 270 206 333 362 ptg000008l:2461597-2466069 Q6NXH2 4.13e-144 Glycoprotein endo-alpha-1,2-mannosidase (Endo-alpha mannosidase) (Endomannosidase) (mEndo) (EC 3.2.1.130) Mus musculus (Mouse) NA GO:0000139; GO:0004559; GO:0004569; GO:0005794 114 FUN_011880 29 1 21 40 7 NA NA NA NA NA NA NA 115 FUN_011881 107 47 75 215 62 ptg000008l:2401449-2407264 Q7Q5R7 8.99e-78 Choline transporter-like 1 Anopheles gambiae (African malaria mosquito) transmembrane transport [GO:0055085] GO:0016020; GO:0022857; GO:0055085 116 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 4.16e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 117 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 1.27e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 118 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 3.02e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 119 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 1.19e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 120 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 2.47e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 121 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 4.71e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 122 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 5e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 123 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 4.03e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 124 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 8.32e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 125 FUN_009932 346 599 385 134 176 ptg000004l:13303549-13305994 Q80XJ3 7.14e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 126 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 7.44e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 127 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 4.11e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 128 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 3.75e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 129 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 3.7e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 130 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 6.45e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 131 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 2.34e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 132 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 1.89e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 133 FUN_009931 50 21 17 16 24 ptg000004l:13266425-13276358 Q96AY4 2.23e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 134 FUN_009930 0 0 7 6 272 NA NA NA NA NA NA NA 135 FUN_032359 1017 521 354 209 107 NA NA NA NA NA NA NA 136 FUN_032358 4923 3441 2697 4250 3330 NA NA NA NA NA NA NA 137 FUN_008080 96 10 47 45 32 NA NA NA NA NA NA NA 138 FUN_024432 1364 8737 47 1441 161 NA NA NA NA NA NA NA 139 FUN_024431 36 146 63 153 28 NA NA NA NA NA NA NA 140 FUN_008083 0 30 1 5 7 NA NA NA NA NA NA NA 141 FUN_032350 2548 2505 2240 1793 1400 NA NA NA NA NA NA NA 142 FUN_032353 1833 1379 1289 2858 2032 NA NA NA NA NA NA NA 143 FUN_032352 958 256 283 624 360 NA NA NA NA NA NA NA 144 FUN_032355 424 515 497 556 788 ptg000023l:31117880-31120651 Q2KJ97 1.56e-56 Neurochondrin Bos taurus (Bovine) bone resorption [GO:0045453]; neuron projection development [GO:0031175]; regulation of neuronal synaptic plasticity [GO:0048168] GO:0005829; GO:0010008; GO:0030425; GO:0031175; GO:0043025; GO:0045453; GO:0048168; GO:0098794 145 FUN_008089 99 196 91 110 188 NA NA NA NA NA NA NA 146 FUN_032357 2208 1672 918 1645 967 NA NA NA NA NA NA NA 147 FUN_024438 10526 9213 5245 26635 17641 NA NA NA NA NA NA NA 148 FUN_038717 1600 2316 1382 1270 848 NA NA NA NA NA NA NA 149 FUN_038716 24 2 41 16 2 NA NA NA NA NA NA NA 150 FUN_038715 142 89 108 203 125 NA NA NA NA NA NA NA 151 FUN_038714 292 33 126 509 76 NA NA NA NA NA NA NA 152 FUN_038711 70 0 6 0 0 NA NA NA NA NA NA NA 153 FUN_038710 0 19 0 0 0 NA NA NA NA NA NA NA 154 FUN_038719 118 102 47 53 25 NA NA NA NA NA NA NA 155 FUN_038718 1322 1056 777 972 524 NA NA NA NA NA NA NA 156 FUN_028924 202 74 86 61 171 NA NA NA NA NA NA NA 157 FUN_028927 171 105 83 186 96 NA NA NA NA NA NA NA 158 FUN_028926 0 0 6 0 0 NA NA NA NA NA NA NA 159 FUN_028921 14 21 10 0 48 NA NA NA NA NA NA NA 160 FUN_028920 210 895 293 467 302 NA NA NA NA NA NA NA 161 FUN_028923 703 1333 691 809 380 NA NA NA NA NA NA NA 162 FUN_028922 0 0 12 0 41 NA NA NA NA NA NA NA 163 FUN_028929 37 19 2 2 10 NA NA NA NA NA NA NA 164 FUN_028928 0 0 0 0 19 NA NA NA NA NA NA NA 165 FUN_011229 0 0 0 0 9 NA NA NA NA NA NA NA 166 FUN_003938 1581 178 887 1456 1048 NA NA NA NA NA NA NA 167 FUN_011222 2 0 20 0 148 NA NA NA NA NA NA NA 168 FUN_011221 0 1078 12 6 33 NA NA NA NA NA NA NA 169 FUN_011224 0 0 30 12 211 NA NA NA NA NA NA NA 170 FUN_002133 0 0 0 0 833 NA NA NA NA NA NA NA 171 FUN_041252 0 0 0 0 14 NA NA NA NA NA NA NA 172 FUN_013333 44 0 46 0 26 NA NA NA NA NA NA NA 173 FUN_013330 457 255 262 286 472 NA NA NA NA NA NA NA 174 FUN_041256 1 162 73 1 13 NA NA NA NA NA NA NA 175 FUN_013334 26 7 10 6 11 NA NA NA NA NA NA NA 176 FUN_041255 376 78 127 572 281 NA NA NA NA NA NA NA 177 FUN_039044 0 0 26 0 49 NA NA NA NA NA NA NA 178 FUN_039047 0 0 0 0 16 NA NA NA NA NA NA NA 179 FUN_039042 0 0 6 67 32 NA NA NA NA NA NA NA 180 FUN_039043 0 0 11 0 0 NA NA NA NA NA NA NA 181 FUN_025430 1546 1929 889 1729 756 ptg000019l:2504704-2608286 Q3ZBV2 2.92e-22 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 182 FUN_025430 1546 1929 889 1729 756 ptg000019l:2504704-2608286 Q3ZBV2 3.91e-22 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 183 FUN_025430 1546 1929 889 1729 756 ptg000019l:2504704-2608286 Q3ZBV2 5.86e-22 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 184 FUN_025430 1546 1929 889 1729 756 ptg000019l:2504704-2608286 Q3ZBV2 1.58e-21 ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DEAD box protein 19A) Bos taurus (Bovine) poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0010494; GO:0016887; GO:0016973 185 FUN_025431 499 374 261 410 768 NA NA NA NA NA NA NA 186 FUN_020848 0 0 0 1 9 NA NA NA NA NA NA NA 187 FUN_020849 178 120 123 160 65 NA NA NA NA NA NA NA 188 FUN_022993 87 121 59 72 28 ptg000017l:2339992-2341252 Q25C93 5.78e-66 Fez family zinc finger protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0007399; GO:0030154; GO:0046872 189 FUN_022990 5226 4521 2385 4074 3823 ptg000017l:2301042-2304924 Q8WUN7 1.1e-32 Ubiquitin domain-containing protein 2 (Dendritic cell-derived ubiquitin-like protein) (DC-UbP) (Ubiquitin-like protein SB72) Homo sapiens (Human) NA GO:0005737 190 FUN_022990 5226 4521 2385 4074 3823 ptg000017l:2301042-2304924 Q8WUN7 1.07e-28 Ubiquitin domain-containing protein 2 (Dendritic cell-derived ubiquitin-like protein) (DC-UbP) (Ubiquitin-like protein SB72) Homo sapiens (Human) NA GO:0005737 191 FUN_022991 968 713 836 814 1069 NA NA NA NA NA NA NA 192 FUN_022996 2010 2955 655 856 947 NA NA NA NA NA NA NA 193 FUN_022997 495 363 345 364 491 NA NA NA NA NA NA NA 194 FUN_022994 40 0 58 5 231 NA NA NA NA NA NA NA 195 FUN_022995 128 8 55 154 187 NA NA NA NA NA NA NA 196 FUN_022998 1644 629 725 1200 1469 NA NA NA NA NA NA NA 197 FUN_022999 0 0 18 0 0 NA NA NA NA NA NA NA 198 FUN_027313 76 988 197 81 204 NA NA NA NA NA NA NA 199 FUN_027312 0 0 22 2 0 NA NA NA NA NA NA NA 200 FUN_027311 145 17 42 53 0 NA NA NA NA NA NA NA 201 FUN_012148 0 0 12 0 4 NA NA NA NA NA NA NA 202 FUN_012149 27413 20639 16679 16353 14433 NA NA NA NA NA NA NA 203 FUN_012142 1592 3330 3630 5494 2386 NA NA NA NA NA NA NA 204 FUN_017311 52 0 0 0 0 NA NA NA NA NA NA NA 205 FUN_012147 1726 1014 805 799 565 NA NA NA NA NA NA NA 206 FUN_037528 59 0 19 11 0 NA NA NA NA NA NA NA 207 FUN_011051 2098 2031 1278 1665 1380 NA NA NA NA NA NA NA 208 FUN_011050 1495 902 1002 1803 1870 ptg000007l:5847377-5895797 Q9JK25 2.03e-21 CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 170) (CLIP-170) (Restin) Rattus norvegicus (Rat) cytoplasmic microtubule organization [GO:0031122]; microtubule bundle formation [GO:0001578]; positive regulation of dendrite development [GO:1900006]; positive regulation of microtubule polymerization [GO:0031116]; protein transport into plasma membrane raft [GO:0044861] GO:0001578; GO:0001726; GO:0005634; GO:0005635; GO:0005737; GO:0005813; GO:0005874; GO:0005881; GO:0008017; GO:0008270; GO:0015630; GO:0015631; GO:0016020; GO:0030659; GO:0031116; GO:0031122; GO:0035371; GO:0044861; GO:0051010; GO:1900006 209 FUN_002526 0 107 167 0 26 NA NA NA NA NA NA NA 210 FUN_011054 298 215 117 192 132 ptg000007l:5922396-5930721 P54965 5.3e-29 Conjugated bile acid hydrolase (CBAH) (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (CBAH-1) (Choloylglycine hydrolase) (EC 3.5.1.24) Clostridium perfringens (strain 13 / Type A) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 211 FUN_038879 4 17 6 4 21 NA NA NA NA NA NA NA 212 FUN_027865 889 0 201 291 6 NA NA NA NA NA NA NA 213 FUN_027867 0 0 318 618 435 NA NA NA NA NA NA NA 214 FUN_027866 213 2082 1379 5531 2413 ptg000021l:12384257-12388189 D9IQ16 5.71e-28 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 215 FUN_027866 213 2082 1379 5531 2413 ptg000021l:12384257-12388189 D9IQ16 3.18e-26 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 216 FUN_027866 213 2082 1379 5531 2413 ptg000021l:12384257-12388189 D9IQ16 1.16e-24 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 217 FUN_027866 213 2082 1379 5531 2413 ptg000021l:12384257-12388189 D9IQ16 1.49e-23 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 218 FUN_027861 213 815 432 2053 1410 ptg000021l:12345712-12349830 D9IQ16 2.05e-32 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 219 FUN_027861 213 815 432 2053 1410 ptg000021l:12345712-12349830 D9IQ16 2.35e-27 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 220 FUN_027861 213 815 432 2053 1410 ptg000021l:12345712-12349830 D9IQ16 1.88e-21 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 221 FUN_027860 131 582 1149 1188 7099 ptg000021l:12338429-12339366 D9IQ16 9.44e-22 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 222 FUN_027860 131 582 1149 1188 7099 ptg000021l:12338429-12339366 D9IQ16 9.54e-22 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 223 FUN_027862 223 9 0 30 8 NA NA NA NA NA NA NA 224 FUN_027868 5688 18109 11882 38289 15173 ptg000021l:12427731-12428824 D9IQ16 1.62e-34 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 225 FUN_027868 5688 18109 11882 38289 15173 ptg000021l:12427731-12428824 D9IQ16 7.7e-29 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 226 FUN_023348 1133 614 636 1111 416 NA NA NA NA NA NA NA 227 FUN_014668 4836 2738 2641 7497 6936 NA NA NA NA NA NA NA 228 FUN_026198 2678 2182 1396 1158 1025 NA NA NA NA NA NA NA 229 FUN_026196 0 0 14 0 0 NA NA NA NA NA NA NA 230 FUN_023341 3417 2528 2383 5228 4933 NA NA NA NA NA NA NA 231 FUN_026194 0 37 0 0 45 NA NA NA NA NA NA NA 232 FUN_026195 67 96 72 84 209 NA NA NA NA NA NA NA 233 FUN_014665 2476 804 1304 1922 1069 NA NA NA NA NA NA NA 234 FUN_014664 10499 8325 7227 11546 9680 NA NA NA NA NA NA NA 235 FUN_023347 176 50 104 115 38 ptg000017l:6543652-6545155 Q924H0 5.13e-34 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 236 FUN_014237 13 31 22 13 164 NA NA NA NA NA NA NA 237 FUN_044270 1 1 4 8 9 NA NA NA NA NA NA NA 238 FUN_005144 0 0 0 0 13 NA NA NA NA NA NA NA 239 FUN_044277 90 10 23 61 79 NA NA NA NA NA NA NA 240 FUN_005145 0 8 0 0 1426 NA NA NA NA NA NA NA 241 FUN_030147 9 0 0 0 8 NA NA NA NA NA NA NA 242 FUN_003961 0 0 0 74 13 NA NA NA NA NA NA NA 243 FUN_044274 994 1670 497 481 336 ptg000131l:9922-15071 Q95KD9 2.81e-30 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165 244 FUN_022534 1607 1992 689 1770 1474 ptg000016l:10228008-10236737 B7WFQ1 9.76e-33 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 245 FUN_022534 1607 1992 689 1770 1474 ptg000016l:10228008-10236737 B7WFQ1 3.11e-32 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 246 FUN_022534 1607 1992 689 1770 1474 ptg000016l:10228008-10236737 B7WFQ1 1.02e-31 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 247 FUN_022534 1607 1992 689 1770 1474 ptg000016l:10228008-10236737 B7WFQ1 1.66e-29 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 248 FUN_022534 1607 1992 689 1770 1474 ptg000016l:10228008-10236737 B7WFQ1 5.11e-29 Uncharacterized skeletal organic matrix protein 2 (Uncharacterized SOMP-2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 249 FUN_014235 0 0 140 44 7 NA NA NA NA NA NA NA 250 FUN_009548 27 0 0 0 0 ptg000004l:8379591-8388916 O00370 2.57e-27 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 251 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 3.98e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 252 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 6.74e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 253 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 1.15e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 254 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 9.37e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 255 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 3.33e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 256 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 1.09e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 257 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 9.76e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 258 FUN_009549 139 8 22 182 116 ptg000004l:8400944-8403991 Q96AY4 8.56e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 259 FUN_009543 21 16 0 11 0 NA NA NA NA NA NA NA 260 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 1.7e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 261 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 6.88e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 262 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 2.31e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 263 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 9.74e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 264 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 1.5e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 265 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 2.03e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 266 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 3.27e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 267 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 3.34e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 268 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 1.67e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 269 FUN_009541 107 0 62 72 77 ptg000004l:8273242-8277122 Q96AY4 1.03e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 270 FUN_009546 0 6 0 41 0 NA NA NA NA NA NA NA 271 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 1.43e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 272 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 8.72e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 273 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 1.68e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 274 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 5.44e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 275 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 3.55e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 276 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 5.81e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 277 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 8.23e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 278 FUN_009544 212 60 71 1519 169 ptg000004l:8306662-8329845 Q96AY4 9.34e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 279 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 7.05e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 280 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 7.05e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 281 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 2.09e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 282 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 2.09e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 283 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 7.28e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 284 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 2.43e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 285 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 9.6e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 286 FUN_009545 202 50 114 1827 105 ptg000004l:8344037-8347797 Q96AY4 4.84e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 287 FUN_041748 0 0 0 6 0 NA NA NA NA NA NA NA 288 FUN_026738 33 23 0 13 0 ptg000020l:12941774-12944824 Q6ZSS7 7.65e-29 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 289 FUN_026739 2663 2067 1462 2688 1627 NA NA NA NA NA NA NA 290 FUN_026730 280 201 36 175 34 NA NA NA NA NA NA NA 291 FUN_026736 94 104 0 31 32 ptg000020l:12928773-12930393 Q8CBH5 6.75e-62 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 292 FUN_026735 30 11 0 11 48 NA NA NA NA NA NA NA 293 FUN_039835 356 338 201 311 529 NA NA NA NA NA NA NA 294 FUN_022438 18 0 0 0 0 NA NA NA NA NA NA NA 295 FUN_039837 812 657 497 740 711 NA NA NA NA NA NA NA 296 FUN_039836 3413 4026 2160 1864 744 NA NA NA NA NA NA NA 297 FUN_039831 298 74 105 91 55 NA NA NA NA NA NA NA 298 FUN_039830 1838 1091 584 966 983 ptg000031l:636434-646769 Q8JGM4 2.18e-43 Sulfhydryl oxidase 1 (EC 1.8.3.2) (Quiescin Q6) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0000139; GO:0003756; GO:0005615; GO:0006457; GO:0016971 299 FUN_025429 210 28 25 62 62 NA NA NA NA NA NA NA 300 FUN_039832 370 363 251 724 444 NA NA NA NA NA NA NA 301 FUN_025427 716 872 149 394 276 NA NA NA NA NA NA NA 302 FUN_022430 896 432 626 819 636 NA NA NA NA NA NA NA 303 FUN_022433 1100 557 569 930 967 NA NA NA NA NA NA NA 304 FUN_022432 2 0 0 6 1 NA NA NA NA NA NA NA 305 FUN_039839 17 36 28 15 46 NA NA NA NA NA NA NA 306 FUN_025422 229 155 45 120 308 NA NA NA NA NA NA NA 307 FUN_022437 585 245 298 661 474 NA NA NA NA NA NA NA 308 FUN_024778 4309 2674 1646 3522 2680 ptg000018l:10951333-10972190 O60264 1.64e-54 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription initiation [GO:0006352]; heterochromatin formation [GO:0031507]; negative regulation of mitotic chromosome condensation [GO:1905213]; negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000183; GO:0000793; GO:0001650; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005677; GO:0005721; GO:0005730; GO:0006275; GO:0006281; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0006357; GO:0008094; GO:0008623; GO:0016479; GO:0016589; GO:0016590; GO:0016887; GO:0031062; GO:0031065; GO:0031213; GO:0031491; GO:0031507; GO:0035066; GO:0035861; GO:0044030; GO:0045740; GO:0045943; GO:0045944; GO:0045945; GO:0090535; GO:0090536; GO:0110016; GO:0140658; GO:0140751; GO:1905213; GO:1990830; GO:2001020 309 FUN_024778 4309 2674 1646 3522 2680 ptg000018l:10951333-10972190 O60264 1.51e-43 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription initiation [GO:0006352]; heterochromatin formation [GO:0031507]; negative regulation of mitotic chromosome condensation [GO:1905213]; negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000183; GO:0000793; GO:0001650; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005677; GO:0005721; GO:0005730; GO:0006275; GO:0006281; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0006357; GO:0008094; GO:0008623; GO:0016479; GO:0016589; GO:0016590; GO:0016887; GO:0031062; GO:0031065; GO:0031213; GO:0031491; GO:0031507; GO:0035066; GO:0035861; GO:0044030; GO:0045740; GO:0045943; GO:0045944; GO:0045945; GO:0090535; GO:0090536; GO:0110016; GO:0140658; GO:0140751; GO:1905213; GO:1990830; GO:2001020 310 FUN_024778 4309 2674 1646 3522 2680 ptg000018l:10951333-10972190 O60264 1.51e-43 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription initiation [GO:0006352]; heterochromatin formation [GO:0031507]; negative regulation of mitotic chromosome condensation [GO:1905213]; negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000183; GO:0000793; GO:0001650; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005677; GO:0005721; GO:0005730; GO:0006275; GO:0006281; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0006357; GO:0008094; GO:0008623; GO:0016479; GO:0016589; GO:0016590; GO:0016887; GO:0031062; GO:0031065; GO:0031213; GO:0031491; GO:0031507; GO:0035066; GO:0035861; GO:0044030; GO:0045740; GO:0045943; GO:0045944; GO:0045945; GO:0090535; GO:0090536; GO:0110016; GO:0140658; GO:0140751; GO:1905213; GO:1990830; GO:2001020 311 FUN_024778 4309 2674 1646 3522 2680 ptg000018l:10951333-10972190 O60264 3.01e-23 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5) (EC 3.6.4.-) (Sucrose nonfermenting protein 2 homolog) (hSNF2H) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription initiation [GO:0006352]; heterochromatin formation [GO:0031507]; negative regulation of mitotic chromosome condensation [GO:1905213]; negative regulation of transcription by RNA polymerase I [GO:0016479]; nucleosome assembly [GO:0006334]; positive regulation of DNA replication [GO:0045740]; positive regulation of histone acetylation [GO:0035066]; positive regulation of histone deacetylation [GO:0031065]; positive regulation of histone methylation [GO:0031062]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; rDNA heterochromatin formation [GO:0000183]; regulation of DNA methylation [GO:0044030]; regulation of DNA replication [GO:0006275]; regulation of DNA-templated transcription [GO:0006355]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000183; GO:0000793; GO:0001650; GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005677; GO:0005721; GO:0005730; GO:0006275; GO:0006281; GO:0006334; GO:0006338; GO:0006352; GO:0006355; GO:0006357; GO:0008094; GO:0008623; GO:0016479; GO:0016589; GO:0016590; GO:0016887; GO:0031062; GO:0031065; GO:0031213; GO:0031491; GO:0031507; GO:0035066; GO:0035861; GO:0044030; GO:0045740; GO:0045943; GO:0045944; GO:0045945; GO:0090535; GO:0090536; GO:0110016; GO:0140658; GO:0140751; GO:1905213; GO:1990830; GO:2001020 312 FUN_024779 514 363 347 753 567 NA NA NA NA NA NA NA 313 FUN_024774 3 0 0 44 40 NA NA NA NA NA NA NA 314 FUN_024775 11816 10453 5871 5813 3607 NA NA NA NA NA NA NA 315 FUN_024776 6253 7011 2797 7439 3917 NA NA NA NA NA NA NA 316 FUN_024770 1187 1065 619 977 490 ptg000018l:10844257-10852424 Q149M9 7.45e-41 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 317 FUN_024770 1187 1065 619 977 490 ptg000018l:10844257-10852424 Q149M9 2.32e-21 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 318 FUN_024771 31 92 228 204 110 NA NA NA NA NA NA NA 319 FUN_024772 76 95 222 86 125 ptg000018l:10865919-10869509 Q149M9 4.24e-36 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 320 FUN_024773 0 0 10 9 9 NA NA NA NA NA NA NA 321 FUN_018807 226 530 103 78 204 NA NA NA NA NA NA NA 322 FUN_018806 1496 1003 771 1518 1204 NA NA NA NA NA NA NA 323 FUN_009062 0 10 0 0 8 NA NA NA NA NA NA NA 324 FUN_018958 0 0 0 0 31 NA NA NA NA NA NA NA 325 FUN_018950 0 0 0 21 0 NA NA NA NA NA NA NA 326 FUN_030689 0 5 0 8 0 NA NA NA NA NA NA NA 327 FUN_030681 1570 949 1344 949 1892 ptg000023l:14674877-14787216 Q99315 2.17e-76 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 328 FUN_030681 1570 949 1344 949 1892 ptg000023l:14674877-14787216 Q99315 6.3e-48 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 329 FUN_030681 1570 949 1344 949 1892 ptg000023l:14674877-14787216 Q99315 6.3e-48 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 330 FUN_030681 1570 949 1344 949 1892 ptg000023l:14674877-14787216 Q99315 3.4e-41 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 331 FUN_030681 1570 949 1344 949 1892 ptg000023l:14674877-14787216 Q99315 6.5e-26 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 332 FUN_030681 1570 949 1344 949 1892 ptg000023l:14674877-14787216 Q99315 6.5e-26 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 333 FUN_030680 78 50 25 37 34 ptg000023l:14672283-14674735 Q8BFQ2 6.46e-42 Transmembrane protein 229B Mus musculus (Mouse) macrophage activation [GO:0042116]; response to bacterium [GO:0009617] GO:0009617; GO:0016020; GO:0042116 334 FUN_030683 0 0 44 0 44 NA NA NA NA NA NA NA 335 FUN_030682 0 0 0 3 24 NA NA NA NA NA NA NA 336 FUN_030686 2255 2026 1766 1896 2081 NA NA NA NA NA NA NA 337 FUN_038058 2897 1387 968 3479 2064 NA NA NA NA NA NA NA 338 FUN_038059 347 283 132 321 126 NA NA NA NA NA NA NA 339 FUN_038054 2004 1581 777 1357 1531 NA NA NA NA NA NA NA 340 FUN_038055 1155 2038 827 823 859 NA NA NA NA NA NA NA 341 FUN_038056 1265 1308 737 770 633 NA NA NA NA NA NA NA 342 FUN_038057 11448 8606 5439 7321 9314 NA NA NA NA NA NA NA 343 FUN_038050 206 30 12 39 13 ptg000027l:1854115-1860596 C3YWU0 1.04e-31 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 344 FUN_038051 430 378 178 521 163 ptg000027l:1862932-1865337 P53472 4.59e-175 Actin, cytoskeletal 1A (EC 3.6.4.-) (Actin, cytoskeletal IA) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 345 FUN_038051 430 378 178 521 163 ptg000027l:1862932-1865337 P53472 2.55e-45 Actin, cytoskeletal 1A (EC 3.6.4.-) (Actin, cytoskeletal IA) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 346 FUN_038052 35894 31415 12040 28973 16987 ptg000027l:1867936-1875846 P69003 1.47e-167 Actin CyI, cytoplasmic (EC 3.6.4.-) Heliocidaris tuberculata (Sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 347 FUN_038052 35894 31415 12040 28973 16987 ptg000027l:1867936-1875846 P69003 1.41e-165 Actin CyI, cytoplasmic (EC 3.6.4.-) Heliocidaris tuberculata (Sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 348 FUN_038052 35894 31415 12040 28973 16987 ptg000027l:1867936-1875846 P69003 3.63e-60 Actin CyI, cytoplasmic (EC 3.6.4.-) Heliocidaris tuberculata (Sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 349 FUN_038052 35894 31415 12040 28973 16987 ptg000027l:1867936-1875846 P69003 3.63e-60 Actin CyI, cytoplasmic (EC 3.6.4.-) Heliocidaris tuberculata (Sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 350 FUN_038052 35894 31415 12040 28973 16987 ptg000027l:1867936-1875846 P69003 5.96e-56 Actin CyI, cytoplasmic (EC 3.6.4.-) Heliocidaris tuberculata (Sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 351 FUN_038052 35894 31415 12040 28973 16987 ptg000027l:1867936-1875846 P69003 5.96e-56 Actin CyI, cytoplasmic (EC 3.6.4.-) Heliocidaris tuberculata (Sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 352 FUN_038053 1793 1007 972 1885 1269 NA NA NA NA NA NA NA 353 FUN_036900 1844 1854 1125 2505 1797 ptg000026l:3245660-3249837 Q99PW8 1.82e-131 Kinesin-like protein KIF17 (MmKIF17) Mus musculus (Mouse) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007017; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016192; GO:0016887; GO:0030030; GO:0031503; GO:0032391; GO:0032839; GO:0036064; GO:0042073; GO:0043005; GO:0098971; GO:1990075 354 FUN_036900 1844 1854 1125 2505 1797 ptg000026l:3245660-3249837 Q99PW8 3.85e-37 Kinesin-like protein KIF17 (MmKIF17) Mus musculus (Mouse) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007017; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016192; GO:0016887; GO:0030030; GO:0031503; GO:0032391; GO:0032839; GO:0036064; GO:0042073; GO:0043005; GO:0098971; GO:1990075 355 FUN_036900 1844 1854 1125 2505 1797 ptg000026l:3245660-3249837 Q99PW8 3.87e-32 Kinesin-like protein KIF17 (MmKIF17) Mus musculus (Mouse) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; intraciliary transport [GO:0042073]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; protein transport [GO:0015031]; protein-containing complex localization [GO:0031503]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007017; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016192; GO:0016887; GO:0030030; GO:0031503; GO:0032391; GO:0032839; GO:0036064; GO:0042073; GO:0043005; GO:0098971; GO:1990075 356 FUN_036901 44 36 26 51 35 NA NA NA NA NA NA NA 357 FUN_036902 188 140 33 203 112 NA NA NA NA NA NA NA 358 FUN_036904 0 6 0 0 15 NA NA NA NA NA NA NA 359 FUN_000604 173 0 62 78 56 NA NA NA NA NA NA NA 360 FUN_036906 0 0 11 0 9 NA NA NA NA NA NA NA 361 FUN_036907 1187 815 367 511 332 ptg000026l:3303004-3309297 P61963 2e-30 DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0005654; GO:0005829; GO:0016363; GO:0016567; GO:0016604; GO:0032991; GO:0080008 362 FUN_036907 1187 815 367 511 332 ptg000026l:3303004-3309297 P61963 2.94e-24 DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog) Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0005654; GO:0005829; GO:0016363; GO:0016567; GO:0016604; GO:0032991; GO:0080008 363 FUN_036908 83 42 3 21 17 NA NA NA NA NA NA NA 364 FUN_036909 89 37 8 25 22 NA NA NA NA NA NA NA 365 FUN_029288 232 153 148 140 424 NA NA NA NA NA NA NA 366 FUN_000608 4071 1741 1723 6323 1897 ntLink_6:4958874-4978947 F1QH17 2.61e-47 Protein-methionine sulfoxide oxidase mical3a (EC 1.14.13.225) (Molecule interacting with CasL protein 3A) (MICAL-3A) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament depolymerization [GO:0030042]; animal organ development [GO:0048513]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887] GO:0003779; GO:0005634; GO:0005737; GO:0005856; GO:0006887; GO:0007010; GO:0016709; GO:0030042; GO:0046872; GO:0048513; GO:0071949 367 FUN_000608 4071 1741 1723 6323 1897 ntLink_6:4958874-4978947 F1QH17 4.76e-44 Protein-methionine sulfoxide oxidase mical3a (EC 1.14.13.225) (Molecule interacting with CasL protein 3A) (MICAL-3A) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament depolymerization [GO:0030042]; animal organ development [GO:0048513]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887] GO:0003779; GO:0005634; GO:0005737; GO:0005856; GO:0006887; GO:0007010; GO:0016709; GO:0030042; GO:0046872; GO:0048513; GO:0071949 368 FUN_000608 4071 1741 1723 6323 1897 ntLink_6:4958874-4978947 F1QH17 1.03e-28 Protein-methionine sulfoxide oxidase mical3a (EC 1.14.13.225) (Molecule interacting with CasL protein 3A) (MICAL-3A) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament depolymerization [GO:0030042]; animal organ development [GO:0048513]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887] GO:0003779; GO:0005634; GO:0005737; GO:0005856; GO:0006887; GO:0007010; GO:0016709; GO:0030042; GO:0046872; GO:0048513; GO:0071949 369 FUN_000608 4071 1741 1723 6323 1897 ntLink_6:4958874-4978947 F1QH17 5.02e-22 Protein-methionine sulfoxide oxidase mical3a (EC 1.14.13.225) (Molecule interacting with CasL protein 3A) (MICAL-3A) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament depolymerization [GO:0030042]; animal organ development [GO:0048513]; cytoskeleton organization [GO:0007010]; exocytosis [GO:0006887] GO:0003779; GO:0005634; GO:0005737; GO:0005856; GO:0006887; GO:0007010; GO:0016709; GO:0030042; GO:0046872; GO:0048513; GO:0071949 370 FUN_030532 17 0 0 0 14 NA NA NA NA NA NA NA 371 FUN_030531 5 0 0 0 27 ptg000023l:11231755-11237004 Q64400 6.46e-81 Histone H3.2 Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 372 FUN_030531 5 0 0 0 27 ptg000023l:11231755-11237004 Q64400 5.88e-80 Histone H3.2 Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 373 FUN_030530 19 0 12 9 147 ptg000023l:11226567-11227330 P84239 3.22e-89 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 374 FUN_004880 1816 827 983 2658 2415 NA NA NA NA NA NA NA 375 FUN_004881 2380 1676 1127 1780 2097 NA NA NA NA NA NA NA 376 FUN_004882 2213 2452 1291 655 1207 NA NA NA NA NA NA NA 377 FUN_004883 240 42 0 30 55 NA NA NA NA NA NA NA 378 FUN_004885 0 0 20 0 41 NA NA NA NA NA NA NA 379 FUN_004887 2902 65 2288 2431 5064 ntLink_8:28386241-28400792 A0A0R4IBK5 1.62e-122 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 380 FUN_004888 17 11 4 11 1 NA NA NA NA NA NA NA 381 FUN_004889 3086 3448 1941 2240 2116 NA NA NA NA NA NA NA 382 FUN_020109 0 0 0 0 11 NA NA NA NA NA NA NA 383 FUN_031483 0 0 0 6 14 NA NA NA NA NA NA NA 384 FUN_020103 23 5 0 605 20 NA NA NA NA NA NA NA 385 FUN_031489 801 1807 496 993 445 ptg000023l:21965956-21973976 P02594 4.18e-33 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 386 FUN_040297 15 30 12 24 23 NA NA NA NA NA NA NA 387 FUN_030493 0 0 0 0 6 ptg000023l:10993199-10995766 P84239 4.88e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 388 FUN_001638 371 309 288 403 369 NA NA NA NA NA NA NA 389 FUN_001639 1311 830 611 1261 1220 NA NA NA NA NA NA NA 390 FUN_001630 6258 4447 4154 4305 2801 NA NA NA NA NA NA NA 391 FUN_001631 2852 3996 2394 4112 3394 NA NA NA NA NA NA NA 392 FUN_001632 3231 1087 855 1224 771 NA NA NA NA NA NA NA 393 FUN_001633 443 208 189 271 291 NA NA NA NA NA NA NA 394 FUN_001634 234 300 221 385 182 NA NA NA NA NA NA NA 395 FUN_001635 0 0 3 3 11 NA NA NA NA NA NA NA 396 FUN_001636 74 44 24 93 70 NA NA NA NA NA NA NA 397 FUN_001637 66 74 48 53 184 NA NA NA NA NA NA NA 398 FUN_007287 41 0 42 3 138 ptg000002l:997741-999339 Q6LAF1 2.19e-46 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 399 FUN_007286 6 0 13 2 73 NA NA NA NA NA NA NA 400 FUN_007285 5 0 2 3 13 ptg000002l:985933-992220 Q9J569 1.03e-21 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 401 FUN_031365 430 52 338 212 662 ptg000023l:20147537-20156389 Q7RTR2 1.84e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 402 FUN_031365 430 52 338 212 662 ptg000023l:20147537-20156389 Q7RTR2 5.06e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 403 FUN_031365 430 52 338 212 662 ptg000023l:20147537-20156389 Q7RTR2 3.38e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 404 FUN_031365 430 52 338 212 662 ptg000023l:20147537-20156389 Q7RTR2 3.46e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 405 FUN_031365 430 52 338 212 662 ptg000023l:20147537-20156389 Q7RTR2 2.05e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 406 FUN_031365 430 52 338 212 662 ptg000023l:20147537-20156389 Q7RTR2 2.48e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 407 FUN_039179 0 1 7 0 48 NA NA NA NA NA NA NA 408 FUN_016891 0 4 0 73 0 NA NA NA NA NA NA NA 409 FUN_036277 2 5 1 3 10 NA NA NA NA NA NA NA 410 FUN_036270 0 0 0 0 11 NA NA NA NA NA NA NA 411 FUN_036278 135 254 166 192 19 NA NA NA NA NA NA NA 412 FUN_033015 363 145 213 508 326 NA NA NA NA NA NA NA 413 FUN_033014 702 504 222 765 551 NA NA NA NA NA NA NA 414 FUN_033017 149 148 219 161 265 NA NA NA NA NA NA NA 415 FUN_028993 201 67 184 156 206 ptg000022l:6895361-6897408 A2AVA0 6.55e-21 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Polydom) Mus musculus (Mouse) cell migration [GO:0016477]; epidermis development [GO:0008544]; epithelial cell-cell adhesion [GO:0090136]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005576; GO:0005615; GO:0005634; GO:0005737; GO:0008544; GO:0010467; GO:0016020; GO:0016477; GO:0031012; GO:0036303; GO:0048014; GO:0090136; GO:0120193 416 FUN_027458 1119 520 1393 10 0 NA NA NA NA NA NA NA 417 FUN_027454 13 15 22 7 32 NA NA NA NA NA NA NA 418 FUN_027456 12 36 63 21 144 NA NA NA NA NA NA NA 419 FUN_027457 29 0 125 4 13 NA NA NA NA NA NA NA 420 FUN_027450 0 6 2 0 0 NA NA NA NA NA NA NA 421 FUN_027451 12 412 0 0 29 NA NA NA NA NA NA NA 422 FUN_027452 109 44 57 68 93 NA NA NA NA NA NA NA 423 FUN_027453 17 33 4 58 29 NA NA NA NA NA NA NA 424 FUN_033013 17 0 54 81 49 NA NA NA NA NA NA NA 425 FUN_033012 251 88 95 186 208 NA NA NA NA NA NA NA 426 FUN_019252 0 0 0 0 19 NA NA NA NA NA NA NA 427 FUN_037775 1561 580 432 1155 437 ptg000026l:13402087-13403266 P48630 3.56e-116 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 428 FUN_006626 227 191 228 153 98 NA NA NA NA NA NA NA 429 FUN_006627 1537 391 445 464 210 NA NA NA NA NA NA NA 430 FUN_006624 730 36 71 141 101 NA NA NA NA NA NA NA 431 FUN_006625 167 37 0 99 45 NA NA NA NA NA NA NA 432 FUN_006622 136 137 53 500 474 NA NA NA NA NA NA NA 433 FUN_006623 0 244 89 162 174 NA NA NA NA NA NA NA 434 FUN_006620 200 0 171 18 23 NA NA NA NA NA NA NA 435 FUN_032597 13 0 8 0 0 NA NA NA NA NA NA NA 436 FUN_032596 341 10 58 22 134 NA NA NA NA NA NA NA 437 FUN_032594 123 0 0 0 204 NA NA NA NA NA NA NA 438 FUN_032593 65 18 12 6 183 NA NA NA NA NA NA NA 439 FUN_032592 57 1 0 0 20 NA NA NA NA NA NA NA 440 FUN_006629 736 882 823 1355 918 NA NA NA NA NA NA NA 441 FUN_042987 121 521 259 514 16 ptg000047l:2755181-2756189 Q60HG2 5.44e-91 Torsin-1A (Dystonia 1 protein) (Torsin ATPase 1) (EC 3.6.4.-) (Torsin family 1 member A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell adhesion [GO:0007155]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein folding [GO:0061077]; ER-associated misfolded protein catabolic process [GO:0071712]; intermediate filament cytoskeleton organization [GO:0045104]; neuron projection development [GO:0031175]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; protein deneddylation [GO:0000338]; protein localization to nucleus [GO:0034504]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein localization to cell surface [GO:2000008]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle transport [GO:0048489]; wound healing, spreading of cells [GO:0044319] GO:0000338; GO:0005524; GO:0005635; GO:0005788; GO:0005856; GO:0006998; GO:0007155; GO:0008021; GO:0016887; GO:0030141; GO:0030426; GO:0030659; GO:0031175; GO:0031965; GO:0034504; GO:0042406; GO:0042802; GO:0044319; GO:0045104; GO:0048489; GO:0048499; GO:0051085; GO:0051584; GO:0061077; GO:0071712; GO:0071763; GO:0140662; GO:1900244; GO:2000008 442 FUN_042986 0 19 0 28 264 NA NA NA NA NA NA NA 443 FUN_042985 0 21 0 0 9 NA NA NA NA NA NA NA 444 FUN_042983 59 0 0 76 127 NA NA NA NA NA NA NA 445 FUN_042982 228 753 35 251 383 ptg000047l:2690313-2698318 Q8BS35 2.54e-21 Alkylglycerol monooxygenase (EC 1.14.16.5) (Transmembrane protein 195) Mus musculus (Mouse) ether lipid metabolic process [GO:0046485]; lipid biosynthetic process [GO:0008610]; membrane lipid metabolic process [GO:0006643] GO:0005506; GO:0005783; GO:0005789; GO:0006643; GO:0008610; GO:0046485; GO:0050479 446 FUN_042981 88 203 61 130 273 NA NA NA NA NA NA NA 447 FUN_003569 2125 6354 2690 10939 10329 ntLink_8:12787445-12791480 R1CW23 1.44e-97 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 448 FUN_003567 0 0 2 0 16 NA NA NA NA NA NA NA 449 FUN_004712 450 277 291 363 540 NA NA NA NA NA NA NA 450 FUN_004714 882 453 495 933 954 NA NA NA NA NA NA NA 451 FUN_004715 147 96 134 36 44 NA NA NA NA NA NA NA 452 FUN_004716 450 464 180 175 245 ntLink_8:26169359-26206332 P0CT39 9.38e-78 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 453 FUN_011279 2809 1786 1448 2811 1718 NA NA NA NA NA NA NA 454 FUN_016584 489 401 474 457 563 NA NA NA NA NA NA NA 455 FUN_041861 14762 15711 8859 11233 8332 ptg000035l:8330950-8343337 P20825 2.46e-90 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 456 FUN_041860 1074 1049 1076 526 494 NA NA NA NA NA NA NA 457 FUN_041863 387 243 217 276 490 NA NA NA NA NA NA NA 458 FUN_041862 9901 6470 3770 6853 5581 ptg000035l:8345462-8365338 Q5PYH7 6.08e-24 Disks large homolog 2 (Postsynaptic density protein 93) (PSD-93) Danio rerio (Zebrafish) (Brachydanio rerio) cell-cell adhesion [GO:0098609]; chemical synaptic transmission [GO:0007268]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; synapse organization [GO:0050808] GO:0007268; GO:0016323; GO:0030054; GO:0030424; GO:0031594; GO:0043005; GO:0043113; GO:0043204; GO:0045197; GO:0050808; GO:0097120; GO:0098609; GO:0098839 459 FUN_041865 545 602 404 702 446 NA NA NA NA NA NA NA 460 FUN_041864 1018 902 655 1113 699 NA NA NA NA NA NA NA 461 FUN_041867 106 124 136 111 262 NA NA NA NA NA NA NA 462 FUN_041866 18009 29514 17826 21166 12131 ptg000035l:8388239-8389201 P49180 1.59e-24 60S ribosomal protein L35a Caenorhabditis elegans cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273] GO:0002181; GO:0003735; GO:0022625; GO:0042273 463 FUN_041869 167 171 56 370 178 ptg000035l:8415934-8419868 Q6Q4G4 1.35e-69 Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE) Theromyzon tessulatum (Duck leech) proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0006508; GO:0008237; GO:0008241; GO:0016020; GO:0046872 464 FUN_041869 167 171 56 370 178 ptg000035l:8415934-8419868 Q6Q4G4 1.27e-23 Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE) Theromyzon tessulatum (Duck leech) proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0006508; GO:0008237; GO:0008241; GO:0016020; GO:0046872 465 FUN_041868 3214 1882 1501 4220 2350 NA NA NA NA NA NA NA 466 FUN_042804 15 0 43 0 40 NA NA NA NA NA NA NA 467 FUN_011143 0 0 18 3 34 NA NA NA NA NA NA NA 468 FUN_011141 4 0 0 0 37 NA NA NA NA NA NA NA 469 FUN_016760 0 0 0 11 6 NA NA NA NA NA NA NA 470 FUN_042801 16 7 46 7 350 NA NA NA NA NA NA NA 471 FUN_013564 0 15 0 0 17 NA NA NA NA NA NA NA 472 FUN_035337 334 102 56 370 282 ptg000025l:6520551-6525254 O95685 1.1e-22 Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0004722; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0042587; GO:0043231; GO:2001069 473 FUN_002381 40 24 11 27 51 NA NA NA NA NA NA NA 474 FUN_002380 195 196 188 404 216 NA NA NA NA NA NA NA 475 FUN_002382 459 196 267 381 334 NA NA NA NA NA NA NA 476 FUN_002384 13 0 0 0 0 NA NA NA NA NA NA NA 477 FUN_002386 0 0 114 46 41 NA NA NA NA NA NA NA 478 FUN_002389 7 0 16 40 0 NA NA NA NA NA NA NA 479 FUN_002388 0 0 0 50 6 NA NA NA NA NA NA NA 480 FUN_040615 5958 6825 3455 5419 2775 NA NA NA NA NA NA NA 481 FUN_012788 567 249 250 397 214 ptg000008l:12856918-12863222 Q5RCR5 7.49e-22 Inactive C-alpha-formylglycine-generating enzyme 2 (Sulfatase-modifying factor 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005783; GO:0005788; GO:0046872 482 FUN_029429 13 99 17 44 0 NA NA NA NA NA NA NA 483 FUN_012780 130 87 69 107 177 NA NA NA NA NA NA NA 484 FUN_012782 25474 23120 13836 26948 21410 NA NA NA NA NA NA NA 485 FUN_012783 42 6 0 25 50 NA NA NA NA NA NA NA 486 FUN_029427 123 421 159 773 140 NA NA NA NA NA NA NA 487 FUN_029426 316 117 85 222 224 ptg000023l:1771151-1780151 Q5H8A4 3.93e-37 GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005783; GO:0005789; GO:0006506; GO:0016020; GO:0016254; GO:0016740; GO:0016780; GO:0051267 488 FUN_029426 316 117 85 222 224 ptg000023l:1771151-1780151 Q5H8A4 3.18e-22 GPI ethanolamine phosphate transferase 2 (EC 2.-.-.-) (GPI7 homolog) (hGPI7) (Phosphatidylinositol-glycan biosynthesis class G protein) (PIG-G) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005783; GO:0005789; GO:0006506; GO:0016020; GO:0016254; GO:0016740; GO:0016780; GO:0051267 489 FUN_029425 243 165 123 422 477 NA NA NA NA NA NA NA 490 FUN_029424 245 125 162 268 217 NA NA NA NA NA NA NA 491 FUN_016498 2238 1606 1520 3710 3406 NA NA NA NA NA NA NA 492 FUN_016499 27 0 53 0 203 ptg000011l:3853405-3857563 P00565 3.26e-50 Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]; response to heat [GO:0009408] GO:0004111; GO:0005524; GO:0005615; GO:0005829; GO:0009408; GO:0016301; GO:0016310; GO:0046314 493 FUN_016499 27 0 53 0 203 ptg000011l:3853405-3857563 P00565 2.57e-45 Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]; response to heat [GO:0009408] GO:0004111; GO:0005524; GO:0005615; GO:0005829; GO:0009408; GO:0016301; GO:0016310; GO:0046314 494 FUN_016499 27 0 53 0 203 ptg000011l:3853405-3857563 P00565 7.01e-43 Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310]; response to heat [GO:0009408] GO:0004111; GO:0005524; GO:0005615; GO:0005829; GO:0009408; GO:0016301; GO:0016310; GO:0046314 495 FUN_040613 287 130 75 93 77 NA NA NA NA NA NA NA 496 FUN_016490 1060 1213 1016 972 1172 ptg000011l:3757513-3761618 Q505F5 4.51e-36 Leucine-rich repeat-containing protein 47 Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432] GO:0003723; GO:0004826; GO:0006432 497 FUN_016491 9213 7996 5128 6163 2877 NA NA NA NA NA NA NA 498 FUN_016492 697 315 272 558 554 NA NA NA NA NA NA NA 499 FUN_040612 76 80 29 66 71 ptg000031l:10989592-11027477 P10394 3.24e-98 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 500 FUN_040612 76 80 29 66 71 ptg000031l:10989592-11027477 P10394 3.76e-59 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 501 FUN_016494 1397 2397 1281 939 343 NA NA NA NA NA NA NA 502 FUN_016495 1147 1251 965 2205 1889 NA NA NA NA NA NA NA 503 FUN_016496 849 1138 682 1380 807 ptg000011l:3816327-3821240 Q80W22 2.44e-53 Threonine synthase-like 2 (TSH2) (mTSH2) (EC 4.2.3.-) Mus musculus (Mouse) 2-oxobutyrate biosynthetic process [GO:0046360]; dephosphorylation [GO:0016311]; serine family amino acid catabolic process [GO:0009071] GO:0009071; GO:0016311; GO:0016829; GO:0030170; GO:0046360; GO:0070905 504 FUN_016497 0 0 7 0 0 NA NA NA NA NA NA NA 505 FUN_040808 10 0 0 4 0 NA NA NA NA NA NA NA 506 FUN_040800 0 0 0 28 0 NA NA NA NA NA NA NA 507 FUN_040801 19 96 5 194 5 NA NA NA NA NA NA NA 508 FUN_040802 55 62 15 60 2 NA NA NA NA NA NA NA 509 FUN_040804 0 5 28 20 0 NA NA NA NA NA NA NA 510 FUN_043579 161 66 73 200 123 NA NA NA NA NA NA NA 511 FUN_000137 0 1 1 0 7 ntLink_4:204726-205104 P35061 3.99e-86 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 512 FUN_043571 235 250 124 149 234 NA NA NA NA NA NA NA 513 FUN_043570 1224 592 1350 1011 1133 NA NA NA NA NA NA NA 514 FUN_043573 10804 7170 5057 7480 5602 NA NA NA NA NA NA NA 515 FUN_043572 653 502 359 849 515 NA NA NA NA NA NA NA 516 FUN_043575 1153 496 662 1929 1741 NA NA NA NA NA NA NA 517 FUN_043574 2353 1898 1143 1813 1947 NA NA NA NA NA NA NA 518 FUN_043577 9 0 0 0 0 NA NA NA NA NA NA NA 519 FUN_010178 0 0 0 9 0 NA NA NA NA NA NA NA 520 FUN_013785 0 26 0 6 0 NA NA NA NA NA NA NA 521 FUN_013781 59 24 51 53 17 NA NA NA NA NA NA NA 522 FUN_013788 169 105 109 117 80 NA NA NA NA NA NA NA 523 FUN_042338 0 0 0 0 25 NA NA NA NA NA NA NA 524 FUN_000949 15 4 45 18 15 NA NA NA NA NA NA NA 525 FUN_042339 0 0 17 0 10 NA NA NA NA NA NA NA 526 FUN_023108 576 645 341 807 484 ptg000017l:3683068-3686744 Q9JME2 1.04e-47 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 527 FUN_023109 2195 1554 2099 3644 2613 NA NA NA NA NA NA NA 528 FUN_023106 21 24 89 42 25 NA NA NA NA NA NA NA 529 FUN_023107 246 182 279 139 761 ptg000017l:3670795-3682506 Q3V1H3 8.86e-68 Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826] GO:0004322; GO:0005507; GO:0005886; GO:0006825; GO:0006826; GO:0006879; GO:0016491; GO:0055072 530 FUN_023107 246 182 279 139 761 ptg000017l:3670795-3682506 Q3V1H3 1.84e-43 Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826] GO:0004322; GO:0005507; GO:0005886; GO:0006825; GO:0006826; GO:0006879; GO:0016491; GO:0055072 531 FUN_023107 246 182 279 139 761 ptg000017l:3670795-3682506 Q3V1H3 7.55e-37 Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879]; copper ion transport [GO:0006825]; iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826] GO:0004322; GO:0005507; GO:0005886; GO:0006825; GO:0006826; GO:0006879; GO:0016491; GO:0055072 532 FUN_023104 193 1364 523 1265 381 NA NA NA NA NA NA NA 533 FUN_023105 3310 4195 2804 4698 1816 NA NA NA NA NA NA NA 534 FUN_023102 33 33 27 14 18 NA NA NA NA NA NA NA 535 FUN_023103 0 13 10 0 18 NA NA NA NA NA NA NA 536 FUN_023100 475 292 174 357 516 NA NA NA NA NA NA NA 537 FUN_023101 3903 4278 2119 3166 1369 NA NA NA NA NA NA NA 538 FUN_042330 0 16 12 26 31 NA NA NA NA NA NA NA 539 FUN_016051 554 323 252 375 595 NA NA NA NA NA NA NA 540 FUN_016053 173 147 134 313 157 ptg000010l:1069855-1076518 P07314 3.6e-23 Glutathione hydrolase 1 proenzyme (EC 3.4.19.13) (Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (EC 2.3.2.2) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) (CD antigen CD224) [Cleaved into: Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain] Rattus norvegicus (Rat) aging [GO:0007568]; amino acid metabolic process [GO:0006520]; cellular response to oxidative stress [GO:0034599]; cysteine biosynthetic process [GO:0019344]; fatty acid metabolic process [GO:0006631]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; leukotriene D4 biosynthetic process [GO:1901750]; leukotriene metabolic process [GO:0006691]; liver regeneration [GO:0097421]; peptide modification [GO:0031179]; proteolysis [GO:0006508]; regulation of immune system process [GO:0002682]; regulation of inflammatory response [GO:0050727]; response to alcohol [GO:0097305]; response to estradiol [GO:0032355]; response to lipopolysaccharide [GO:0032496]; response to tumor necrosis factor [GO:0034612]; spermatogenesis [GO:0007283]; zymogen activation [GO:0031638] GO:0000048; GO:0002682; GO:0002951; GO:0005615; GO:0005886; GO:0006508; GO:0006520; GO:0006536; GO:0006631; GO:0006691; GO:0006750; GO:0006751; GO:0007283; GO:0007568; GO:0016755; GO:0019344; GO:0031179; GO:0031638; GO:0031982; GO:0032355; GO:0032496; GO:0034599; GO:0034612; GO:0036374; GO:0050727; GO:0061017; GO:0070365; GO:0097305; GO:0097421; GO:0102953; GO:0103068; GO:1901750 541 FUN_042334 2633 3534 2677 5915 5952 NA NA NA NA NA NA NA 542 FUN_007076 223 137 36 120 58 NA NA NA NA NA NA NA 543 FUN_028482 1237 743 323 578 594 ptg000021l:20555489-20557728 Q9N126 1.28e-25 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 544 FUN_028483 164 29 25 42 52 NA NA NA NA NA NA NA 545 FUN_028480 176 141 154 218 222 ptg000021l:20541522-20543276 Q9Y2G3 3.54e-33 Phospholipid-transporting ATPase IF (EC 7.6.2.1) (ATPase IR) (ATPase class VI type 11B) (P4-ATPase flippase complex alpha subunit ATP11B) Homo sapiens (Human) aminophospholipid transport [GO:0015917]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005637; GO:0005783; GO:0005802; GO:0005886; GO:0006811; GO:0015075; GO:0015917; GO:0016020; GO:0016887; GO:0031901; GO:0034220; GO:0035577; GO:0045332; GO:0055037; GO:0055038; GO:0090555; GO:0090556; GO:0140326; GO:1990531 546 FUN_028486 1181 730 782 1927 1311 NA NA NA NA NA NA NA 547 FUN_028487 1652 575 956 1367 1491 NA NA NA NA NA NA NA 548 FUN_028484 159 105 95 128 116 NA NA NA NA NA NA NA 549 FUN_009388 120 0 80 5 203 ptg000004l:6237635-6253974 B8VIU6 1.38e-27 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 550 FUN_009389 16 0 0 0 22 ptg000004l:6264818-6268452 B8VIU6 5.92e-29 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 551 FUN_009381 1588 1147 1113 1536 2308 NA NA NA NA NA NA NA 552 FUN_009382 383 327 187 172 496 ptg000004l:6158882-6164783 O35261 2.1e-26 Transcription factor E2F3 (E2F-3) Mus musculus (Mouse) G1/S transition of mitotic cell cycle [GO:0000082]; negative regulation of fat cell proliferation [GO:0070345]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; protein import into nucleus [GO:0006606]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000082; GO:0000977; GO:0000978; GO:0000981; GO:0000987; GO:0001216; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0006606; GO:0008284; GO:0043565; GO:0045893; GO:0045944; GO:0046983; GO:0070345; GO:0090575; GO:1905461; GO:1990837 553 FUN_009383 989 594 512 666 526 ptg000004l:6169596-6172697 P98069 3.17e-29 Bone morphogenetic protein 1 homolog (EC 3.4.24.-) (SUBMP) Strongylocentrotus purpuratus (Purple sea urchin) dorsal/ventral pattern formation [GO:0009953]; protein processing [GO:0016485] GO:0004222; GO:0005509; GO:0005615; GO:0008270; GO:0009953; GO:0016485 554 FUN_009384 4 9 0 44 26 NA NA NA NA NA NA NA 555 FUN_009385 55 0 117 98 98 NA NA NA NA NA NA NA 556 FUN_009386 12 68 8 51 56 ptg000004l:6209653-6219584 B8VIU6 8.07e-29 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 557 FUN_009387 0 0 41 0 76 ptg000004l:6229367-6235320 B8VIU6 1.27e-34 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 558 FUN_031889 1821 124 1 818 427 NA NA NA NA NA NA NA 559 FUN_011925 2805 1454 1370 1596 1057 NA NA NA NA NA NA NA 560 FUN_011924 2301 2554 1248 1673 1189 NA NA NA NA NA NA NA 561 FUN_011927 3154 2889 1741 3447 2875 ptg000008l:3195745-3207089 O60476 6.77e-24 Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; Golgi apparatus mannose trimming [GO:1904381]; lung alveolus development [GO:0048286]; N-glycan processing [GO:0006491]; protein glycosylation [GO:0006486]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0000139; GO:0004571; GO:0005509; GO:0005783; GO:0005794; GO:0005975; GO:0006486; GO:0006491; GO:0007585; GO:0016020; GO:0048286; GO:0070062; GO:1904381 562 FUN_011926 306 198 205 140 258 NA NA NA NA NA NA NA 563 FUN_011921 1935 1845 943 1641 1454 NA NA NA NA NA NA NA 564 FUN_011920 748 1218 700 801 574 ptg000008l:3096885-3100350 A4Q9E4 2.69e-106 Probable tubulin polyglutamylase TTLL2 (EC 6.-.-.-) (Tubulin--tyrosine ligase-like protein 2) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005929; GO:0015631; GO:0018095; GO:0046872; GO:0070740 565 FUN_011923 14 36 2 31 12 NA NA NA NA NA NA NA 566 FUN_011922 6183 5981 2552 5203 3409 ptg000008l:3118689-3161923 Q03460 3.47e-40 Glutamate synthase [NADH], amyloplastic (EC 1.4.1.14) (NADH-GOGAT) Medicago sativa (Alfalfa) glutamine metabolic process [GO:0006541]; L-glutamate biosynthetic process [GO:0097054] GO:0005506; GO:0006541; GO:0009501; GO:0010181; GO:0016040; GO:0050660; GO:0051538; GO:0097054 567 FUN_000948 1991 1530 1229 1215 1011 NA NA NA NA NA NA NA 568 FUN_011929 301 499 217 153 265 NA NA NA NA NA NA NA 569 FUN_011928 466 546 179 376 346 ptg000008l:3218096-3219212 Q5E9H9 2.5e-40 Palmitoyl-protein thioesterase ABHD10, mitochondrial (EC 3.1.2.22) (Acyl-protein thioesterase ABHD10) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10) (Mycophenolic acid acyl-glucuronide esterase, mitochondrial) (EC 3.1.1.93) Bos taurus (Bovine) glucuronoside catabolic process [GO:0019391]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0004553; GO:0005739; GO:0005829; GO:0008474; GO:0019391; GO:0102390 570 FUN_011928 466 546 179 376 346 ptg000008l:3218096-3219212 Q5E9H9 1.35e-22 Palmitoyl-protein thioesterase ABHD10, mitochondrial (EC 3.1.2.22) (Acyl-protein thioesterase ABHD10) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10) (Mycophenolic acid acyl-glucuronide esterase, mitochondrial) (EC 3.1.1.93) Bos taurus (Bovine) glucuronoside catabolic process [GO:0019391]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0004553; GO:0005739; GO:0005829; GO:0008474; GO:0019391; GO:0102390 571 FUN_023003 732 389 293 398 685 ptg000017l:2452113-2552036 P14381 6.05e-87 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 572 FUN_025629 756 686 270 755 304 NA NA NA NA NA NA NA 573 FUN_025628 124 89 41 72 20 NA NA NA NA NA NA NA 574 FUN_025625 322 377 328 638 475 NA NA NA NA NA NA NA 575 FUN_025624 166 57 80 147 90 NA NA NA NA NA NA NA 576 FUN_025627 20 0 0 0 7 NA NA NA NA NA NA NA 577 FUN_025626 1305 1114 970 1124 829 NA NA NA NA NA NA NA 578 FUN_025621 43 107 53 0 0 NA NA NA NA NA NA NA 579 FUN_025622 0 1 3 6 0 NA NA NA NA NA NA NA 580 FUN_008163 91 0 3 0 0 NA NA NA NA NA NA NA 581 FUN_024573 34 45 34 4 59 NA NA NA NA NA NA NA 582 FUN_024570 574 254 224 638 668 ptg000018l:8480800-8485255 O95671 6.98e-25 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 583 FUN_008167 34 34 3 21 18 NA NA NA NA NA NA NA 584 FUN_024577 3857 2224 2059 4897 3463 ptg000018l:8527225-8589726 Q2LD37 8.24e-25 Bridge-like lipid transfer protein family member 1 (Fragile site-associated protein) Homo sapiens (Human) endocytic recycling [GO:0032456]; endosomal transport [GO:0016197]; intermembrane lipid transfer [GO:0120009]; phagocytosis [GO:0006909]; regulation of cell growth [GO:0001558]; regulation of epithelial cell differentiation [GO:0030856]; synaptic vesicle endocytosis [GO:0048488] GO:0001558; GO:0005634; GO:0005789; GO:0005886; GO:0006909; GO:0016020; GO:0016197; GO:0030856; GO:0031966; GO:0032456; GO:0048488; GO:0098793; GO:0120009; GO:0140268; GO:1904121 585 FUN_024574 14 0 0 18 0 NA NA NA NA NA NA NA 586 FUN_008164 101 0 4 0 0 NA NA NA NA NA NA NA 587 FUN_028370 34 0 0 9 13 NA NA NA NA NA NA NA 588 FUN_024578 231 132 196 442 281 NA NA NA NA NA NA NA 589 FUN_031885 6 0 0 0 1 NA NA NA NA NA NA NA 590 FUN_029993 0 42 0 0 0 NA NA NA NA NA NA NA 591 FUN_044131 6 4 11 4 114 NA NA NA NA NA NA NA 592 FUN_044133 17 11 15 20 55 NA NA NA NA NA NA NA 593 FUN_029997 2 0 0 0 51 NA NA NA NA NA NA NA 594 FUN_044135 6 25 13 14 110 NA NA NA NA NA NA NA 595 FUN_044136 11 15 17 20 60 NA NA NA NA NA NA NA 596 FUN_044137 58 202 82 155 450 NA NA NA NA NA NA NA 597 FUN_044139 0 0 0 2 86 NA NA NA NA NA NA NA 598 FUN_029999 0 24 0 0 0 NA NA NA NA NA NA NA 599 FUN_028373 0 0 52 4 185 NA NA NA NA NA NA NA 600 FUN_025196 37 2 72 2 203 ptg000018l:15722673-15727148 Q6LAF1 3.84e-44 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 601 FUN_025194 0 0 7 0 0 ptg000018l:15719067-15721201 P35067 5.31e-74 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 602 FUN_025193 0 0 0 2 23 NA NA NA NA NA NA NA 603 FUN_015120 19 11 0 0 0 NA NA NA NA NA NA NA 604 FUN_015123 12 0 14 28 16 NA NA NA NA NA NA NA 605 FUN_015122 81 75 290 455 325 NA NA NA NA NA NA NA 606 FUN_015125 9 0 0 0 3 NA NA NA NA NA NA NA 607 FUN_035419 787 897 604 598 634 NA NA NA NA NA NA NA 608 FUN_015127 16 31 0 31 13 NA NA NA NA NA NA NA 609 FUN_024436 1889 1220 1011 2783 1414 NA NA NA NA NA NA NA 610 FUN_015129 9 0 0 25 27 NA NA NA NA NA NA NA 611 FUN_015128 0 0 0 5 23 NA NA NA NA NA NA NA 612 FUN_008086 1366 930 661 681 1071 NA NA NA NA NA NA NA 613 FUN_007130 3 0 10 0 19 NA NA NA NA NA NA NA 614 FUN_030421 9 0 11 0 39 ptg000023l:10830359-10831122 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 615 FUN_008087 1220 1522 779 1290 1039 NA NA NA NA NA NA NA 616 FUN_035416 600 383 238 433 420 NA NA NA NA NA NA NA 617 FUN_024433 14 1689 18 284 34 NA NA NA NA NA NA NA 618 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 3.02e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 619 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 5.22e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 620 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 2.69e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 621 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 3.54e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 622 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 3.86e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 623 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 3.93e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 624 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 2.36e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 625 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 5.79e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 626 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 4.17e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 627 FUN_035415 1054 783 755 594 797 ptg000025l:7216984-7219720 Q80XJ3 3.92e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 628 FUN_008081 40322 24075 20596 28138 23768 NA NA NA NA NA NA NA 629 FUN_008082 1499 2633 1213 1117 728 ptg000002l:7798110-7799476 Q5R8Z6 1.39e-25 Multiple coagulation factor deficiency protein 2 homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0005509; GO:0005783; GO:0005793; GO:0005794; GO:0015031; GO:0016192 630 FUN_035413 6092 6524 3188 4545 3860 ptg000025l:7190394-7201482 Q9BVG8 3.34e-25 Kinesin-like protein KIFC3 Homo sapiens (Human) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] GO:0003777; GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0007601; GO:0008017; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0070062; GO:0090136 631 FUN_035413 6092 6524 3188 4545 3860 ptg000025l:7190394-7201482 Q9BVG8 5.33e-22 Kinesin-like protein KIFC3 Homo sapiens (Human) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] GO:0003777; GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0007601; GO:0008017; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0070062; GO:0090136 632 FUN_024430 28 122 41 137 72 NA NA NA NA NA NA NA 633 FUN_007133 10 14 23 17 37 NA NA NA NA NA NA NA 634 FUN_030424 1 0 2 0 7 ptg000023l:10836663-10838923 P84239 7.08e-87 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 635 FUN_038524 4553 3094 2333 4146 4463 ptg000027l:8313921-8372346 C5J7W8 2.4e-50 Serine/threonine-protein kinase SMG1 (smg-1) (EC 2.7.11.1) (Nonsense-mediated mRNA decay-associated PI3K-related kinase SMG1) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of macroautophagy [GO:0016242]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; protein phosphorylation [GO:0006468]; TOR signaling [GO:0031929] GO:0000184; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0016242; GO:0031929; GO:0031931; GO:0031932 636 FUN_038525 1239 734 519 1530 683 NA NA NA NA NA NA NA 637 FUN_038526 3112 2148 1373 4596 4082 NA NA NA NA NA NA NA 638 FUN_038527 34 76 0 0 0 NA NA NA NA NA NA NA 639 FUN_038520 0 37 33 48 44 NA NA NA NA NA NA NA 640 FUN_038521 0 0 0 20 18 NA NA NA NA NA NA NA 641 FUN_038523 4635 3476 2060 3621 3331 NA NA NA NA NA NA NA 642 FUN_023920 38949 33327 23385 33472 11101 NA NA NA NA NA NA NA 643 FUN_023921 2746 1867 1292 2842 2094 NA NA NA NA NA NA NA 644 FUN_023922 776 514 467 612 1027 ptg000018l:180310-193235 Q3UMC0 3.93e-48 Ribosome biogenesis protein SPATA5 (EC 3.6.4.10) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) Mus musculus (Mouse) brain development [GO:0007420]; cell differentiation [GO:0030154]; ribosomal large subunit biogenesis [GO:0042273]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0005739; GO:0005819; GO:0007283; GO:0007420; GO:0016887; GO:0030154; GO:0042273; GO:1990275 645 FUN_023922 776 514 467 612 1027 ptg000018l:180310-193235 Q3UMC0 4.11e-23 Ribosome biogenesis protein SPATA5 (EC 3.6.4.10) (Spermatogenesis-associated factor protein) (Spermatogenesis-associated protein 5) Mus musculus (Mouse) brain development [GO:0007420]; cell differentiation [GO:0030154]; ribosomal large subunit biogenesis [GO:0042273]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0005739; GO:0005819; GO:0007283; GO:0007420; GO:0016887; GO:0030154; GO:0042273; GO:1990275 646 FUN_023923 90 23 55 34 160 NA NA NA NA NA NA NA 647 FUN_023924 1756 1163 877 1517 1501 ptg000018l:200784-220084 Q9NBX4 1.33e-22 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 648 FUN_038529 18 0 20 10 0 NA NA NA NA NA NA NA 649 FUN_023926 32 0 7 32 8 NA NA NA NA NA NA NA 650 FUN_023927 200 72 42 202 252 NA NA NA NA NA NA NA 651 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 1.21e-84 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 652 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 1.06e-61 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 653 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 2.35e-60 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 654 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 5.49e-59 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 655 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 1.27e-53 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 656 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 6.56e-41 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 657 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 6.16e-35 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 658 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 1.38e-32 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 659 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 3.13e-27 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 660 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 3.73e-27 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 661 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 1.27e-26 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 662 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 2.76e-26 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 663 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 2.74e-25 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 664 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 4.28e-25 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 665 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 9.28e-25 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 666 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 1.33e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 667 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 3.65e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 668 FUN_008088 4090 1887 1741 6132 3095 ptg000002l:7846002-7872355 B3EWY9 2.42e-23 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 669 FUN_032354 1252 1246 619 2172 1645 NA NA NA NA NA NA NA 670 FUN_024439 1923 1559 1200 3722 2609 NA NA NA NA NA NA NA 671 FUN_032356 2039 1313 1342 1165 924 NA NA NA NA NA NA NA 672 FUN_007135 2259 2951 1165 2218 688 NA NA NA NA NA NA NA 673 FUN_038635 0 0 4 4 37 NA NA NA NA NA NA NA 674 FUN_038636 879 187 337 715 464 NA NA NA NA NA NA NA 675 FUN_028626 5 9 46 29 40 NA NA NA NA NA NA NA 676 FUN_004952 0 26 0 0 0 NA NA NA NA NA NA NA 677 FUN_028624 0 0 0 96 22 NA NA NA NA NA NA NA 678 FUN_023637 547 457 160 3739 464 NA NA NA NA NA NA NA 679 FUN_038632 6573 3492 2171 4131 2715 ptg000027l:9497667-9518363 Q5R8Q7 1.58e-31 GTP-binding protein 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) GTP metabolic process [GO:0046039]; positive regulation of mRNA catabolic process [GO:0061014] GO:0000177; GO:0003924; GO:0005525; GO:0005829; GO:0046039; GO:0061014 680 FUN_023630 508 442 177 430 395 NA NA NA NA NA NA NA 681 FUN_004951 27 1 1 0 3 NA NA NA NA NA NA NA 682 FUN_023631 1010 432 400 420 348 ptg000017l:10098500-10103721 Q6IZ48 7.83e-33 Transcription factor Sox-8 Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) NA GO:0003677; GO:0005634 683 FUN_028620 12 0 4 9 68 NA NA NA NA NA NA NA 684 FUN_023633 2104 1298 1051 1609 1485 ptg000017l:10122079-10139181 Q5ZKJ5 2.49e-41 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 685 FUN_023633 2104 1298 1051 1609 1485 ptg000017l:10122079-10139181 Q5ZKJ5 3.91e-30 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 686 FUN_023633 2104 1298 1051 1609 1485 ptg000017l:10122079-10139181 Q5ZKJ5 1.45e-28 Transmembrane protein 180 (Major facilitator superfamily domain-containing 13A) Gallus gallus (Chicken) NA GO:0016020 687 FUN_044214 0 67 65 46 136 NA NA NA NA NA NA NA 688 FUN_027127 1713 924 677 1367 1146 NA NA NA NA NA NA NA 689 FUN_027120 0 0 1 0 148 NA NA NA NA NA NA NA 690 FUN_027121 2 0 6 0 36 NA NA NA NA NA NA NA 691 FUN_027128 1534 1077 1239 1854 1831 NA NA NA NA NA NA NA 692 FUN_004260 1079 1006 527 650 772 NA NA NA NA NA NA NA 693 FUN_033955 13 22 49 68 104 NA NA NA NA NA NA NA 694 FUN_033956 517 472 218 1349 850 NA NA NA NA NA NA NA 695 FUN_004263 226 175 146 179 286 NA NA NA NA NA NA NA 696 FUN_004264 1440 490 659 996 613 NA NA NA NA NA NA NA 697 FUN_004265 1194 596 658 826 731 NA NA NA NA NA NA NA 698 FUN_004266 18 48 48 50 14 NA NA NA NA NA NA NA 699 FUN_033953 9701 3149 1290 3581 1582 NA NA NA NA NA NA NA 700 FUN_004268 898 4233 1386 1775 1293 NA NA NA NA NA NA NA 701 FUN_004269 73 42 98 23 98 NA NA NA NA NA NA NA 702 FUN_033958 1126 527 659 625 637 ptg000024l:3138559-3151041 Q149M9 6.24e-78 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 703 FUN_033959 787 633 604 576 409 NA NA NA NA NA NA NA 704 FUN_023649 1885 1277 1865 1849 2225 NA NA NA NA NA NA NA 705 FUN_000978 348 200 180 311 151 NA NA NA NA NA NA NA 706 FUN_026541 1436 887 1080 1378 1294 ptg000020l:10276854-10290464 P55197 3.25e-26 Protein AF-10 (ALL1-fused gene from chromosome 10 protein) Homo sapiens (Human) histone H3-K27 methylation [GO:0070734]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0031491; GO:0032991; GO:0042393; GO:0045944; GO:0046872; GO:0070734 707 FUN_026541 1436 887 1080 1378 1294 ptg000020l:10276854-10290464 P55197 3.25e-26 Protein AF-10 (ALL1-fused gene from chromosome 10 protein) Homo sapiens (Human) histone H3-K27 methylation [GO:0070734]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0031491; GO:0032991; GO:0042393; GO:0045944; GO:0046872; GO:0070734 708 FUN_024467 151 192 154 64 212 NA NA NA NA NA NA NA 709 FUN_018859 18 0 11 32 163 NA NA NA NA NA NA NA 710 FUN_018856 26 0 22 48 18 NA NA NA NA NA NA NA 711 FUN_018855 0 0 0 0 52 NA NA NA NA NA NA NA 712 FUN_043871 0 0 3 0 15 NA NA NA NA NA NA NA 713 FUN_019109 0 0 0 0 94 NA NA NA NA NA NA NA 714 FUN_019105 0 0 0 0 19 NA NA NA NA NA NA NA 715 FUN_019104 46 11 0 31 65 NA NA NA NA NA NA NA 716 FUN_019103 0 0 0 14 0 NA NA NA NA NA NA NA 717 FUN_019102 0 0 0 8 0 NA NA NA NA NA NA NA 718 FUN_019101 0 0 0 0 37 NA NA NA NA NA NA NA 719 FUN_023647 7110 7614 5117 7289 3041 NA NA NA NA NA NA NA 720 FUN_011518 0 0 0 0 14 NA NA NA NA NA NA NA 721 FUN_023641 0 11 18 0 13 ptg000017l:10211215-10219601 A2RTF1 3.34e-31 Cation channel sperm-associated auxiliary subunit beta (CatSper-beta) Mus musculus (Mouse) sperm capacitation [GO:0048240] GO:0005929; GO:0034702; GO:0036128; GO:0048240; GO:0097228 722 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 723 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 724 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 6.48e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 725 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 5.18e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 726 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 6.56e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 727 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 8.78e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 728 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 2.86e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 729 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 4.47e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 730 FUN_043074 35 20 5 51 25 ptg000047l:3751238-3755623 Q96AY4 4.47e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 731 FUN_011515 0 4 0 13 0 NA NA NA NA NA NA NA 732 FUN_021469 0 248 0 0 40 NA NA NA NA NA NA NA 733 FUN_021466 456 250 199 433 156 NA NA NA NA NA NA NA 734 FUN_021465 322 161 128 267 272 NA NA NA NA NA NA NA 735 FUN_021464 28 0 15 0 78 NA NA NA NA NA NA NA 736 FUN_021463 2095 2591 2461 2293 1514 NA NA NA NA NA NA NA 737 FUN_021462 6 0 12 7 14 NA NA NA NA NA NA NA 738 FUN_021461 23 0 5 4 138 NA NA NA NA NA NA NA 739 FUN_021460 0 0 0 0 41 NA NA NA NA NA NA NA 740 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 5.46e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 741 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 4.94e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 742 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 5.08e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 743 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 3.95e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 744 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 4.8e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 745 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 1.88e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 746 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 1.11e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 747 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 4.1e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 748 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 1.55e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 749 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 1.42e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 750 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 6.16e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 751 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 1.67e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 752 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 1.4e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 753 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 2.51e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 754 FUN_043072 16 13 44 36 31 ptg000047l:3708757-3715281 Q96AY4 2.89e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 755 FUN_023643 2133 2040 1101 884 1060 ptg000017l:10239436-10243866 Q9DAA6 5e-27 Exosome complex component CSL4 (Exosome component 1) Mus musculus (Mouse) RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA processing [GO:0006364] GO:0000176; GO:0000177; GO:0000178; GO:0003723; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0101019 756 FUN_035448 1155 760 575 664 895 ptg000025l:7533852-7545307 O54991 1.75e-28 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 757 FUN_035449 1270 1373 614 920 589 NA NA NA NA NA NA NA 758 FUN_035444 12591 9880 6108 11179 8390 ptg000025l:7486038-7501952 Q9DBH0 3.41e-29 NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) Mus musculus (Mouse) extracellular transport [GO:0006858]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of protein transport [GO:0051224]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0004842; GO:0005576; GO:0005634; GO:0005737; GO:0006366; GO:0006858; GO:0010629; GO:0016567; GO:0032410; GO:0034765; GO:0042391; GO:0043161; GO:0043433; GO:0045892; GO:0045944; GO:0051224; GO:0051865; GO:0061629; GO:0061630; GO:0070534; GO:1901016 759 FUN_035444 12591 9880 6108 11179 8390 ptg000025l:7486038-7501952 Q9DBH0 3.41e-29 NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) Mus musculus (Mouse) extracellular transport [GO:0006858]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of protein transport [GO:0051224]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0004842; GO:0005576; GO:0005634; GO:0005737; GO:0006366; GO:0006858; GO:0010629; GO:0016567; GO:0032410; GO:0034765; GO:0042391; GO:0043161; GO:0043433; GO:0045892; GO:0045944; GO:0051224; GO:0051865; GO:0061629; GO:0061630; GO:0070534; GO:1901016 760 FUN_035444 12591 9880 6108 11179 8390 ptg000025l:7486038-7501952 Q9DBH0 3.41e-29 NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) Mus musculus (Mouse) extracellular transport [GO:0006858]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of protein transport [GO:0051224]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0004842; GO:0005576; GO:0005634; GO:0005737; GO:0006366; GO:0006858; GO:0010629; GO:0016567; GO:0032410; GO:0034765; GO:0042391; GO:0043161; GO:0043433; GO:0045892; GO:0045944; GO:0051224; GO:0051865; GO:0061629; GO:0061630; GO:0070534; GO:1901016 761 FUN_035444 12591 9880 6108 11179 8390 ptg000025l:7486038-7501952 Q9DBH0 1.79e-22 NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) Mus musculus (Mouse) extracellular transport [GO:0006858]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of protein transport [GO:0051224]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0004842; GO:0005576; GO:0005634; GO:0005737; GO:0006366; GO:0006858; GO:0010629; GO:0016567; GO:0032410; GO:0034765; GO:0042391; GO:0043161; GO:0043433; GO:0045892; GO:0045944; GO:0051224; GO:0051865; GO:0061629; GO:0061630; GO:0070534; GO:1901016 762 FUN_035444 12591 9880 6108 11179 8390 ptg000025l:7486038-7501952 Q9DBH0 1.79e-22 NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase WWP2) (WW domain-containing protein 2) Mus musculus (Mouse) extracellular transport [GO:0006858]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of protein transport [GO:0051224]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transporter activity [GO:0032410]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of potassium ion transmembrane transporter activity [GO:1901016]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000209; GO:0004842; GO:0005576; GO:0005634; GO:0005737; GO:0006366; GO:0006858; GO:0010629; GO:0016567; GO:0032410; GO:0034765; GO:0042391; GO:0043161; GO:0043433; GO:0045892; GO:0045944; GO:0051224; GO:0051865; GO:0061629; GO:0061630; GO:0070534; GO:1901016 763 FUN_035445 0 0 0 213 0 NA NA NA NA NA NA NA 764 FUN_035446 0 15 0 60 0 NA NA NA NA NA NA NA 765 FUN_035447 68 59 0 176 0 NA NA NA NA NA NA NA 766 FUN_035440 120 76 37 94 60 ptg000025l:7455932-7469923 Q03650 4.29e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 767 FUN_035440 120 76 37 94 60 ptg000025l:7455932-7469923 Q03650 6.66e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 768 FUN_035440 120 76 37 94 60 ptg000025l:7455932-7469923 Q03650 1.23e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 769 FUN_035440 120 76 37 94 60 ptg000025l:7455932-7469923 Q03650 2.38e-35 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 770 FUN_035441 690 550 614 605 609 ptg000025l:7473741-7474974 Q6Z7K5 2.6e-59 Metal tolerance protein 3 (OsMTP3) Oryza sativa subsp. japonica (Rice) NA GO:0005384; GO:0005774; GO:0008324; GO:0016020 771 FUN_035443 195 169 287 218 340 NA NA NA NA NA NA NA 772 FUN_031563 291 164 177 286 228 NA NA NA NA NA NA NA 773 FUN_031562 467 204 192 338 350 NA NA NA NA NA NA NA 774 FUN_031561 440 606 260 455 384 NA NA NA NA NA NA NA 775 FUN_031560 1201 975 679 721 626 NA NA NA NA NA NA NA 776 FUN_031567 1102 573 279 813 669 NA NA NA NA NA NA NA 777 FUN_031566 7422 6700 4402 6179 4932 NA NA NA NA NA NA NA 778 FUN_031565 2010 693 666 1786 1639 ptg000023l:22913923-22922380 P57103 3.26e-146 Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3) Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; modulation of excitatory postsynaptic potential [GO:0098815]; myelination [GO:0042552]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808] GO:0002244; GO:0005432; GO:0005516; GO:0005741; GO:0005789; GO:0005886; GO:0006811; GO:0006851; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0014069; GO:0014819; GO:0016020; GO:0016528; GO:0030001; GO:0030424; GO:0030425; GO:0031594; GO:0035725; GO:0042383; GO:0042552; GO:0043025; GO:0043197; GO:0043204; GO:0043679; GO:0045202; GO:0046872; GO:0048471; GO:0048709; GO:0050808; GO:0051560; GO:0060291; GO:0070161; GO:0070588; GO:0071456; GO:0071901; GO:0098703; GO:0098794; GO:0098815; GO:0099580; GO:1903779 779 FUN_031565 2010 693 666 1786 1639 ptg000023l:22913923-22922380 P57103 2.09e-34 Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3) Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; modulation of excitatory postsynaptic potential [GO:0098815]; myelination [GO:0042552]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808] GO:0002244; GO:0005432; GO:0005516; GO:0005741; GO:0005789; GO:0005886; GO:0006811; GO:0006851; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0014069; GO:0014819; GO:0016020; GO:0016528; GO:0030001; GO:0030424; GO:0030425; GO:0031594; GO:0035725; GO:0042383; GO:0042552; GO:0043025; GO:0043197; GO:0043204; GO:0043679; GO:0045202; GO:0046872; GO:0048471; GO:0048709; GO:0050808; GO:0051560; GO:0060291; GO:0070161; GO:0070588; GO:0071456; GO:0071901; GO:0098703; GO:0098794; GO:0098815; GO:0099580; GO:1903779 780 FUN_031565 2010 693 666 1786 1639 ptg000023l:22913923-22922380 P57103 2.47e-34 Sodium/calcium exchanger 3 (Na(+)/Ca(2+)-exchange protein 3) (Solute carrier family 8 member 3) Homo sapiens (Human) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hypoxia [GO:0071456]; hematopoietic progenitor cell differentiation [GO:0002244]; ion transport [GO:0006811]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; modulation of excitatory postsynaptic potential [GO:0098815]; myelination [GO:0042552]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; oligodendrocyte differentiation [GO:0048709]; regulation of cardiac conduction [GO:1903779]; regulation of skeletal muscle contraction [GO:0014819]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808] GO:0002244; GO:0005432; GO:0005516; GO:0005741; GO:0005789; GO:0005886; GO:0006811; GO:0006851; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0014069; GO:0014819; GO:0016020; GO:0016528; GO:0030001; GO:0030424; GO:0030425; GO:0031594; GO:0035725; GO:0042383; GO:0042552; GO:0043025; GO:0043197; GO:0043204; GO:0043679; GO:0045202; GO:0046872; GO:0048471; GO:0048709; GO:0050808; GO:0051560; GO:0060291; GO:0070161; GO:0070588; GO:0071456; GO:0071901; GO:0098703; GO:0098794; GO:0098815; GO:0099580; GO:1903779 781 FUN_031564 1659 1079 911 1430 1320 NA NA NA NA NA NA NA 782 FUN_031569 3025 2697 2347 1720 1980 ptg000023l:22984695-22999372 Q19291 2.91e-24 Doublesex- and mab-3-related transcription factor dmd-5 Caenorhabditis elegans male anatomical structure morphogenesis [GO:0090598]; negative regulation of synapse pruning [GO:1905807]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007548; GO:0046872; GO:0090598; GO:1905807 783 FUN_031568 0 0 4 16 25 NA NA NA NA NA NA NA 784 FUN_020738 0 0 0 3 15 NA NA NA NA NA NA NA 785 FUN_020739 0 0 8 0 0 NA NA NA NA NA NA NA 786 FUN_020736 0 0 21 9 14 NA NA NA NA NA NA NA 787 FUN_020737 0 12 0 5 27 NA NA NA NA NA NA NA 788 FUN_032140 2365 2286 2553 1907 2413 NA NA NA NA NA NA NA 789 FUN_032141 935 700 667 627 485 NA NA NA NA NA NA NA 790 FUN_032142 677 503 488 490 198 NA NA NA NA NA NA NA 791 FUN_032143 2145 2595 2072 2353 1273 NA NA NA NA NA NA NA 792 FUN_032144 1957 2325 872 1375 1384 NA NA NA NA NA NA NA 793 FUN_032145 2129 3366 1184 1405 1010 NA NA NA NA NA NA NA 794 FUN_032146 1960 2277 922 2724 1862 NA NA NA NA NA NA NA 795 FUN_032147 13614 19171 4712 22400 10075 ptg000023l:29201856-29206874 Q9ULZ9 3.35e-23 Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP) Homo sapiens (Human) collagen catabolic process [GO:0030574]; drinking behavior [GO:0042756]; extracellular matrix organization [GO:0030198]; kidney development [GO:0001822]; proteolysis [GO:0006508] GO:0001822; GO:0004222; GO:0005576; GO:0005886; GO:0006508; GO:0008047; GO:0008270; GO:0030198; GO:0030574; GO:0031012; GO:0042756; GO:0070006 796 FUN_032148 336 365 405 327 452 ptg000023l:29210705-29216174 Q10835 1.42e-28 Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13) Xenopus laevis (African clawed frog) bone morphogenesis [GO:0060349]; collagen catabolic process [GO:0030574]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005518; GO:0005576; GO:0006508; GO:0008270; GO:0022617; GO:0030574; GO:0031012; GO:0060349 797 FUN_032149 489 122 184 267 251 NA NA NA NA NA NA NA 798 FUN_008361 365 164 50 421 188 ptg000002l:10749926-10754337 B3EX02 9.3e-50 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 799 FUN_008360 140 107 35 129 77 NA NA NA NA NA NA NA 800 FUN_008363 990 419 175 721 423 ptg000002l:10764550-10769629 B3EX02 1.24e-28 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 801 FUN_008362 1096 710 292 991 467 ptg000002l:10754488-10763004 B3EX02 4.61e-28 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 802 FUN_008367 2458 2217 1776 3014 2157 ptg000002l:10794862-10812441 Q5S007 3.29e-33 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin) Homo sapiens (Human) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; canonical Wnt signaling pathway [GO:0060070]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein processing involved in protein targeting to mitochondrion [GO:1903217]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to mitochondrion [GO:0070585]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of mitochondrial fission [GO:0090140]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005615; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008017; GO:0008104; GO:0008340; GO:0009267; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036479; GO:0039706; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0045121; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060070; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070062; GO:0070585; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090140; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902823; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903217; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 803 FUN_008366 184 148 160 112 87 ptg000002l:10791984-10792628 H9JW44 2.03e-30 Chitin deacetylase 7 (BmCDA7) (EC 3.5.1.41) Bombyx mori (Silk moth) chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004099; GO:0005615; GO:0006032; GO:0046872 804 FUN_008369 4887 7044 3655 3521 4054 NA NA NA NA NA NA NA 805 FUN_008368 1418 1134 672 1029 676 ptg000002l:10813725-10815541 Q8TB61 1.07e-115 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (PAPS transporter 1) (Putative MAPK-activating protein PM15) (Putative NF-kappa-B-activating protein 48) (Solute carrier family 35 member B2) Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate transport [GO:0046963]; 5'-adenylyl sulfate transmembrane transport [GO:1902558]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0000139; GO:0005789; GO:0005794; GO:0016020; GO:0022857; GO:0043123; GO:0046963; GO:0046964; GO:1902558 806 FUN_000175 0 0 3 0 13 ntLink_4:292684-293447 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 807 FUN_000177 0 0 2 0 16 ntLink_4:296750-297513 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 808 FUN_000171 3 0 5 0 16 ntLink_4:284552-285315 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 809 FUN_000173 3 0 4 1 13 ntLink_4:288618-289381 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 810 FUN_000179 6 0 2 0 19 ntLink_4:300816-301579 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 811 FUN_007747 0 0 0 10 34 NA NA NA NA NA NA NA 812 FUN_007744 7 1119 0 4 3 ptg000002l:4170449-4180861 Q9NBX4 3.85e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 813 FUN_007744 7 1119 0 4 3 ptg000002l:4170449-4180861 Q9NBX4 3.85e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 814 FUN_007745 0 0 12 0 0 NA NA NA NA NA NA NA 815 FUN_007742 0 0 6 0 0 NA NA NA NA NA NA NA 816 FUN_007743 0 405 0 0 0 NA NA NA NA NA NA NA 817 FUN_007748 825 1926 300 616 724 NA NA NA NA NA NA NA 818 FUN_007749 156 393 193 395 248 ptg000002l:4278581-4315441 P0CT40 8.71e-83 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 819 FUN_000288 221 181 239 163 242 NA NA NA NA NA NA NA 820 FUN_000289 905 518 753 600 982 NA NA NA NA NA NA NA 821 FUN_005670 12 0 0 0 5 NA NA NA NA NA NA NA 822 FUN_000287 208 113 116 107 203 ntLink_6:1074166-1075941 Q14314 1.03e-34 Fibroleukin (Fibrinogen-like protein 2) (pT49) Homo sapiens (Human) negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005576; GO:0005577; GO:0005615; GO:0043381; GO:0050687; GO:0062023; GO:0070062; GO:1904813 823 FUN_005672 0 0 2 0 7 NA NA NA NA NA NA NA 824 FUN_000285 1476 759 562 765 598 NA NA NA NA NA NA NA 825 FUN_000283 51 110 15 60 90 ntLink_6:1036768-1038660 Q9I8C7 2.25e-65 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 826 FUN_005676 0 0 3 0 20 NA NA NA NA NA NA NA 827 FUN_000281 86 122 51 21 53 NA NA NA NA NA NA NA 828 FUN_007921 483 138 295 227 416 NA NA NA NA NA NA NA 829 FUN_007926 872 424 537 505 459 ptg000002l:6275597-6277344 Q7SY06 2.94e-60 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase) (HACD) (Protein-tyrosine phosphatase-like A domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid elongation [GO:0030497]; sphingolipid biosynthetic process [GO:0030148]; very long-chain fatty acid biosynthetic process [GO:0042761] GO:0005783; GO:0005789; GO:0018812; GO:0030148; GO:0030497; GO:0042761; GO:0102158; GO:0102343; GO:0102344; GO:0102345 830 FUN_008267 271 123 144 79 217 NA NA NA NA NA NA NA 831 FUN_007927 302 189 172 272 262 NA NA NA NA NA NA NA 832 FUN_033236 0 0 0 0 41 NA NA NA NA NA NA NA 833 FUN_007925 350 262 294 743 605 NA NA NA NA NA NA NA 834 FUN_043785 52 38 20 0 0 NA NA NA NA NA NA NA 835 FUN_019067 41 0 0 6 27 NA NA NA NA NA NA NA 836 FUN_016903 0 0 0 9 0 NA NA NA NA NA NA NA 837 FUN_016900 0 0 22 0 0 NA NA NA NA NA NA NA 838 FUN_016901 296 58 0 96 19 ptg000011l:8624481-8632512 Q96AY4 5.54e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 839 FUN_016901 296 58 0 96 19 ptg000011l:8624481-8632512 Q96AY4 1.99e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 840 FUN_016901 296 58 0 96 19 ptg000011l:8624481-8632512 Q96AY4 6.28e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 841 FUN_016906 32 16 19 186 10 NA NA NA NA NA NA NA 842 FUN_016907 1 0 0 38 24 NA NA NA NA NA NA NA 843 FUN_016905 104 120 0 25 38 ptg000011l:8685860-8689295 Q96AY4 5.49e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 844 FUN_016905 104 120 0 25 38 ptg000011l:8685860-8689295 Q96AY4 8.6e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 845 FUN_016905 104 120 0 25 38 ptg000011l:8685860-8689295 Q96AY4 1.69e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 846 FUN_016905 104 120 0 25 38 ptg000011l:8685860-8689295 Q96AY4 4.46e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 847 FUN_016905 104 120 0 25 38 ptg000011l:8685860-8689295 Q96AY4 6.71e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 848 FUN_016908 4 0 0 362 0 NA NA NA NA NA NA NA 849 FUN_016909 4 0 13 14 52 NA NA NA NA NA NA NA 850 FUN_003485 2023 1775 1107 2560 1405 NA NA NA NA NA NA NA 851 FUN_003487 2134 2654 1646 6902 15583 NA NA NA NA NA NA NA 852 FUN_003480 8 17 55 37 93 NA NA NA NA NA NA NA 853 FUN_003482 0 0 0 0 15 NA NA NA NA NA NA NA 854 FUN_003489 218 83 72 100 164 NA NA NA NA NA NA NA 855 FUN_003488 883 2091 1224 1913 2610 NA NA NA NA NA NA NA 856 FUN_005331 1064 436 522 245 696 NA NA NA NA NA NA NA 857 FUN_014348 29 43 0 0 0 NA NA NA NA NA NA NA 858 FUN_005330 1063 433 687 458 1089 ntLink_8:34079351-34082428 Q3UZD5 1.12e-48 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 859 FUN_005330 1063 433 687 458 1089 ntLink_8:34079351-34082428 Q3UZD5 4.24e-26 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 860 FUN_000125 4 0 9 1 16 ntLink_4:182213-182976 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 861 FUN_004109 1027 557 536 1607 992 NA NA NA NA NA NA NA 862 FUN_003738 0 0 0 0 37 NA NA NA NA NA NA NA 863 FUN_040303 269 182 206 187 153 ptg000031l:6727366-6735158 P22770 4.6e-35 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 864 FUN_004100 3039 3827 1761 5248 3948 ntLink_8:19281646-19295845 Q32NH8 2.66e-38 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-4) (Phospholipase C-delta-4) (PLC-delta-4) Xenopus laevis (African clawed frog) intracellular signal transduction [GO:0035556]; lipid catabolic process [GO:0016042] GO:0004435; GO:0005509; GO:0005634; GO:0005783; GO:0016020; GO:0016042; GO:0035556 865 FUN_004102 250 156 76 498 401 NA NA NA NA NA NA NA 866 FUN_004106 120 0 4 314 4 NA NA NA NA NA NA NA 867 FUN_014345 0 0 0 0 14 NA NA NA NA NA NA NA 868 FUN_005337 5793 5908 4156 5024 3675 NA NA NA NA NA NA NA 869 FUN_004949 2685 1375 992 1848 1145 ntLink_8:29199275-29221698 P53410 3.89e-33 Insulin gene enhancer protein ISL-2 (Islet-2) Gallus gallus (Chicken) axonogenesis [GO:0007409]; neuron fate specification [GO:0048665]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526] GO:0000981; GO:0000987; GO:0005634; GO:0006357; GO:0007409; GO:0032526; GO:0046872; GO:0048665 870 FUN_036007 1985 1059 814 1044 517 ptg000025l:14403152-14411052 Q9QZ85 1.02e-38 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 871 FUN_036007 1985 1059 814 1044 517 ptg000025l:14403152-14411052 Q9QZ85 1.4e-38 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 872 FUN_005336 3982 6096 3772 6689 4506 NA NA NA NA NA NA NA 873 FUN_014343 0 2 0 0 10 NA NA NA NA NA NA NA 874 FUN_014340 1528 666 367 2146 2383 ptg000008l:35549059-35577564 P50532 1.98e-21 Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4) (Chromosome assembly protein XCAP-C) (Chromosome-associated protein C) Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic chromosome condensation [GO:0007076] GO:0005524; GO:0005634; GO:0005694; GO:0005829; GO:0007076; GO:0016887; GO:0051301 875 FUN_003846 6350 3459 3642 7423 7047 NA NA NA NA NA NA NA 876 FUN_016714 37 51 36 122 61 NA NA NA NA NA NA NA 877 FUN_036006 996 1012 381 442 526 ptg000025l:14399474-14401675 Q9QZ85 3.64e-27 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 878 FUN_034278 4646 2851 2535 3308 2356 ptg000024l:6966528-6979772 Q7QG73 8.24e-39 AP-2 complex subunit alpha (Alpha-adaptin) Anopheles gambiae (African malaria mosquito) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; protein transport [GO:0015031]; synaptic vesicle endocytosis [GO:0048488] GO:0005886; GO:0005905; GO:0006886; GO:0015031; GO:0030122; GO:0035615; GO:0048488; GO:0072583; GO:0098793; GO:0140312 879 FUN_034278 4646 2851 2535 3308 2356 ptg000024l:6966528-6979772 Q7QG73 1.16e-23 AP-2 complex subunit alpha (Alpha-adaptin) Anopheles gambiae (African malaria mosquito) clathrin-dependent endocytosis [GO:0072583]; intracellular protein transport [GO:0006886]; protein transport [GO:0015031]; synaptic vesicle endocytosis [GO:0048488] GO:0005886; GO:0005905; GO:0006886; GO:0015031; GO:0030122; GO:0035615; GO:0048488; GO:0072583; GO:0098793; GO:0140312 880 FUN_034279 1460 1058 767 1311 1211 NA NA NA NA NA NA NA 881 FUN_034270 0 16 0 0 0 NA NA NA NA NA NA NA 882 FUN_034272 0 49 0 0 0 NA NA NA NA NA NA NA 883 FUN_034273 0 347 4 0 0 NA NA NA NA NA NA NA 884 FUN_034274 1113 722 877 939 1307 NA NA NA NA NA NA NA 885 FUN_034275 447 403 305 512 752 NA NA NA NA NA NA NA 886 FUN_034276 1202 517 890 1070 988 NA NA NA NA NA NA NA 887 FUN_003840 3124 438 734 1653 1334 NA NA NA NA NA NA NA 888 FUN_002468 408 297 175 430 357 NA NA NA NA NA NA NA 889 FUN_002469 4208 2157 2618 5724 3992 ntLink_8:1923224-1935684 Q7Z6Z7 3.89e-107 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0043161; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:1903955; GO:1904813 890 FUN_002469 4208 2157 2618 5724 3992 ntLink_8:1923224-1935684 Q7Z6Z7 1.16e-43 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0043161; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:1903955; GO:1904813 891 FUN_002469 4208 2157 2618 5724 3992 ntLink_8:1923224-1935684 Q7Z6Z7 8.64e-41 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0043161; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:1903955; GO:1904813 892 FUN_002469 4208 2157 2618 5724 3992 ntLink_8:1923224-1935684 Q7Z6Z7 5.7e-31 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0043161; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:1903955; GO:1904813 893 FUN_002465 0 0 0 0 21 ntLink_8:1865046-1866855 P53766 3.68e-32 Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) Dictyostelium discoideum (Social amoeba) base-excision repair, AP site formation via deaminated base removal [GO:0097510] GO:0004844; GO:0005634; GO:0005739; GO:0097510 894 FUN_002467 27 9 0 0 18 NA NA NA NA NA NA NA 895 FUN_002460 113 2 53 0 92 NA NA NA NA NA NA NA 896 FUN_002461 17 0 13 12 40 NA NA NA NA NA NA NA 897 FUN_002462 15 2 24 48 90 NA NA NA NA NA NA NA 898 FUN_002463 1424 1199 617 925 766 ntLink_8:1832222-1849884 P55861 2.11e-41 DNA replication licensing factor mcm2 (EC 3.6.4.12) (BM28-homolog) (Minichromosome maintenance protein 2) (xMCM2) (p112) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; negative regulation of DNA helicase activity [GO:1905775]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162; GO:1905775 899 FUN_002463 1424 1199 617 925 766 ntLink_8:1832222-1849884 P55861 2.5e-27 DNA replication licensing factor mcm2 (EC 3.6.4.12) (BM28-homolog) (Minichromosome maintenance protein 2) (xMCM2) (p112) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; negative regulation of DNA helicase activity [GO:1905775]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162; GO:1905775 900 FUN_002463 1424 1199 617 925 766 ntLink_8:1832222-1849884 P55861 1.5e-25 DNA replication licensing factor mcm2 (EC 3.6.4.12) (BM28-homolog) (Minichromosome maintenance protein 2) (xMCM2) (p112) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; negative regulation of DNA helicase activity [GO:1905775]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162; GO:1905775 901 FUN_002463 1424 1199 617 925 766 ntLink_8:1832222-1849884 P55861 2.78e-21 DNA replication licensing factor mcm2 (EC 3.6.4.12) (BM28-homolog) (Minichromosome maintenance protein 2) (xMCM2) (p112) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; negative regulation of DNA helicase activity [GO:1905775]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0004386; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162; GO:1905775 902 FUN_012379 2473 1378 984 2162 1767 NA NA NA NA NA NA NA 903 FUN_012378 2130 2834 1515 2315 685 NA NA NA NA NA NA NA 904 FUN_012375 4526 2927 1915 4485 2725 NA NA NA NA NA NA NA 905 FUN_012374 372 470 183 534 568 ptg000008l:8349841-8350924 Q9N294 5.28e-24 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 906 FUN_012377 519 204 239 475 518 NA NA NA NA NA NA NA 907 FUN_012376 1190 1080 709 1078 1358 NA NA NA NA NA NA NA 908 FUN_012371 0 0 14 0 0 NA NA NA NA NA NA NA 909 FUN_012373 16 0 9 0 0 NA NA NA NA NA NA NA 910 FUN_012372 0 6 0 0 0 NA NA NA NA NA NA NA 911 FUN_013422 38 15 29 22 61 NA NA NA NA NA NA NA 912 FUN_013423 0 11 28 8 97 NA NA NA NA NA NA NA 913 FUN_013420 207 185 333 243 546 NA NA NA NA NA NA NA 914 FUN_013421 8581 5961 3103 6598 5355 NA NA NA NA NA NA NA 915 FUN_014434 1011 637 620 302 649 ptg000009l:116661-125891 Q9UG01 4.21e-28 Intraflagellar transport protein 172 homolog Homo sapiens (Human) bone development [GO:0060348]; brain development [GO:0007420]; cilium assembly [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; dorsal/ventral pattern formation [GO:0009953]; embryonic camera-type eye morphogenesis [GO:0048596]; epidermis development [GO:0008544]; heart looping [GO:0001947]; hindgut development [GO:0061525]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; left/right axis specification [GO:0070986]; limb development [GO:0060173]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of smoothened signaling pathway [GO:0045879]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of smoothened signaling pathway [GO:0045880]; protein processing [GO:0016485]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522] GO:0001843; GO:0001947; GO:0005929; GO:0005930; GO:0007219; GO:0007224; GO:0007420; GO:0008544; GO:0009953; GO:0010839; GO:0016485; GO:0021522; GO:0030992; GO:0031122; GO:0035720; GO:0036064; GO:0042073; GO:0043616; GO:0045879; GO:0045880; GO:0048596; GO:0060021; GO:0060173; GO:0060271; GO:0060348; GO:0061525; GO:0070986; GO:0097225; GO:0097228; GO:0097542; GO:0097598; GO:1903561; GO:1905515 916 FUN_014434 1011 637 620 302 649 ptg000009l:116661-125891 Q9UG01 4.21e-28 Intraflagellar transport protein 172 homolog Homo sapiens (Human) bone development [GO:0060348]; brain development [GO:0007420]; cilium assembly [GO:0060271]; cytoplasmic microtubule organization [GO:0031122]; dorsal/ventral pattern formation [GO:0009953]; embryonic camera-type eye morphogenesis [GO:0048596]; epidermis development [GO:0008544]; heart looping [GO:0001947]; hindgut development [GO:0061525]; intraciliary anterograde transport [GO:0035720]; intraciliary transport [GO:0042073]; keratinocyte proliferation [GO:0043616]; left/right axis specification [GO:0070986]; limb development [GO:0060173]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of smoothened signaling pathway [GO:0045879]; neural tube closure [GO:0001843]; non-motile cilium assembly [GO:1905515]; Notch signaling pathway [GO:0007219]; positive regulation of smoothened signaling pathway [GO:0045880]; protein processing [GO:0016485]; roof of mouth development [GO:0060021]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522] GO:0001843; GO:0001947; GO:0005929; GO:0005930; GO:0007219; GO:0007224; GO:0007420; GO:0008544; GO:0009953; GO:0010839; GO:0016485; GO:0021522; GO:0030992; GO:0031122; GO:0035720; GO:0036064; GO:0042073; GO:0043616; GO:0045879; GO:0045880; GO:0048596; GO:0060021; GO:0060173; GO:0060271; GO:0060348; GO:0061525; GO:0070986; GO:0097225; GO:0097228; GO:0097542; GO:0097598; GO:1903561; GO:1905515 917 FUN_014435 36 7 65 0 18 NA NA NA NA NA NA NA 918 FUN_014436 50 9 51 56 96 NA NA NA NA NA NA NA 919 FUN_013425 134 68 18 57 168 NA NA NA NA NA NA NA 920 FUN_014438 1724 1199 1594 2292 2637 NA NA NA NA NA NA NA 921 FUN_014439 369 324 147 418 307 ptg000009l:210056-216628 Q9WUV0 2.72e-41 Origin recognition complex subunit 5 Mus musculus (Mouse) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0000808; GO:0003688; GO:0005524; GO:0005654; GO:0005664; GO:0005829; GO:0006260; GO:0006270; GO:0006275 922 FUN_013428 57 8 10 0 40 NA NA NA NA NA NA NA 923 FUN_013429 0 52 0 0 70 NA NA NA NA NA NA NA 924 FUN_034880 1176 908 657 903 541 ptg000025l:1183491-1185159 Q0VC84 4.48e-90 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1) Bos taurus (Bovine) angiogenesis [GO:0001525]; intestinal epithelial cell development [GO:0060576]; kidney development [GO:0001822]; O-glycan processing, core 1 [GO:0016267] GO:0001525; GO:0001822; GO:0016020; GO:0016263; GO:0016267; GO:0046872; GO:0060576 925 FUN_011487 0 0 3 5 33 NA NA NA NA NA NA NA 926 FUN_011485 0 0 6 4 5 NA NA NA NA NA NA NA 927 FUN_029386 589 135 152 181 323 NA NA NA NA NA NA NA 928 FUN_029387 0 0 0 0 18 NA NA NA NA NA NA NA 929 FUN_029384 337 171 50 117 136 NA NA NA NA NA NA NA 930 FUN_029385 448 0 0 23 103 NA NA NA NA NA NA NA 931 FUN_029382 1779 1873 183 236 1200 NA NA NA NA NA NA NA 932 FUN_000900 4345 3399 1826 3053 2650 NA NA NA NA NA NA NA 933 FUN_000902 0 0 0 0 34 NA NA NA NA NA NA NA 934 FUN_000909 1092 1572 698 1254 802 NA NA NA NA NA NA NA 935 FUN_000908 89695 72353 48846 105054 71604 ntLink_6:5921826-5932391 Q9R194 2.16e-49 Cryptochrome-2 Mus musculus (Mouse) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein import into nucleus [GO:0006606]; regulation of circadian rhythm [GO:0042752]; regulation of sodium-dependent phosphate transport [GO:2000118]; response to activity [GO:0014823]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416] GO:0000122; GO:0000976; GO:0003677; GO:0003684; GO:0003697; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006606; GO:0007623; GO:0009416; GO:0009881; GO:0014823; GO:0016607; GO:0016922; GO:0019900; GO:0019901; GO:0019902; GO:0019915; GO:0032515; GO:0032868; GO:0032922; GO:0042593; GO:0042752; GO:0042754; GO:0043153; GO:0045892; GO:0071949; GO:2000118; GO:2000323; GO:2000850 936 FUN_029388 157 0 31 81 0 NA NA NA NA NA NA NA 937 FUN_029389 303 77 50 105 84 NA NA NA NA NA NA NA 938 FUN_009779 25 30 11 8 35 ptg000004l:11492490-11497593 Q96AY4 7.69e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 939 FUN_009779 25 30 11 8 35 ptg000004l:11492490-11497593 Q96AY4 6.66e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 940 FUN_009779 25 30 11 8 35 ptg000004l:11492490-11497593 Q96AY4 2.11e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 941 FUN_009779 25 30 11 8 35 ptg000004l:11492490-11497593 Q96AY4 1.24e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 942 FUN_009779 25 30 11 8 35 ptg000004l:11492490-11497593 Q96AY4 6.48e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 943 FUN_009779 25 30 11 8 35 ptg000004l:11492490-11497593 Q96AY4 4.23e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 944 FUN_009778 3176 1658 1041 3136 2234 NA NA NA NA NA NA NA 945 FUN_009775 0 12 8 0 0 NA NA NA NA NA NA NA 946 FUN_009774 112 990 1056 214 80 ptg000004l:11387222-11391797 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 947 FUN_009774 112 990 1056 214 80 ptg000004l:11387222-11391797 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 948 FUN_009774 112 990 1056 214 80 ptg000004l:11387222-11391797 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 949 FUN_009774 112 990 1056 214 80 ptg000004l:11387222-11391797 Q96AY4 4.19e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 950 FUN_009774 112 990 1056 214 80 ptg000004l:11387222-11391797 Q96AY4 1.63e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 951 FUN_009777 8985 4393 4268 8482 5434 NA NA NA NA NA NA NA 952 FUN_009776 2108 1504 1422 2513 2375 NA NA NA NA NA NA NA 953 FUN_009771 6986 4731 4039 7764 6551 NA NA NA NA NA NA NA 954 FUN_009770 2 0 4 4 19 NA NA NA NA NA NA NA 955 FUN_009773 673 893 663 1020 1170 NA NA NA NA NA NA NA 956 FUN_009772 446 317 450 618 601 NA NA NA NA NA NA NA 957 FUN_012599 793 1665 4060 1838 1573 ptg000008l:10281087-10331380 P10978 0 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 958 FUN_012598 1637 1094 980 507 1663 NA NA NA NA NA NA NA 959 FUN_029650 338 71 74 36 92 ptg000023l:4123541-4126215 E7FAM5 9.64e-60 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 960 FUN_029651 0 0 9 0 3 NA NA NA NA NA NA NA 961 FUN_029652 58 140 53 95 89 ptg000023l:4138784-4142131 E7FAM5 8.09e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 962 FUN_029653 0 7 3 8 12 NA NA NA NA NA NA NA 963 FUN_029654 58 72 16 90 71 ptg000023l:4147753-4151190 E7FAM5 1.8e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 964 FUN_012594 534 220 174 407 242 NA NA NA NA NA NA NA 965 FUN_029656 0 0 15 1 34 NA NA NA NA NA NA NA 966 FUN_012596 767 464 242 568 477 ptg000008l:10225115-10232012 Q6AYL5 5.37e-28 Splicing factor 3B subunit 4 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of mRNA splicing, via spliceosome [GO:0048026] GO:0000398; GO:0003723; GO:0005634; GO:0005681; GO:0005684; GO:0005689; GO:0048026; GO:0071005; GO:1990935 967 FUN_016289 198 107 55 58 177 NA NA NA NA NA NA NA 968 FUN_016288 2558 1366 1291 2301 2905 NA NA NA NA NA NA NA 969 FUN_016281 8 5 7 9 7 NA NA NA NA NA NA NA 970 FUN_016280 553 462 406 496 632 NA NA NA NA NA NA NA 971 FUN_016282 1874 512 998 1597 1518 NA NA NA NA NA NA NA 972 FUN_016284 3336 2278 1512 2191 2027 NA NA NA NA NA NA NA 973 FUN_016287 185 106 23 172 99 NA NA NA NA NA NA NA 974 FUN_016286 2400 1564 792 1505 1333 NA NA NA NA NA NA NA 975 FUN_015741 170 0 161 0 0 NA NA NA NA NA NA NA 976 FUN_010992 92 76 21 99 89 NA NA NA NA NA NA NA 977 FUN_010990 876 528 387 487 271 NA NA NA NA NA NA NA 978 FUN_015745 0 19 0 19 0 NA NA NA NA NA NA NA 979 FUN_010995 4 0 4 0 37 NA NA NA NA NA NA NA 980 FUN_015746 26 0 0 0 0 NA NA NA NA NA NA NA 981 FUN_010999 829 262 471 746 629 NA NA NA NA NA NA NA 982 FUN_010998 0 0 0 0 12 NA NA NA NA NA NA NA 983 FUN_034750 0 21 0 0 40 NA NA NA NA NA NA NA 984 FUN_042213 0 21 12 0 50 NA NA NA NA NA NA NA 985 FUN_016131 31708 20715 17764 20262 14152 NA NA NA NA NA NA NA 986 FUN_016130 7234 5695 3866 4395 3134 NA NA NA NA NA NA NA 987 FUN_016137 1189 975 529 809 623 ptg000010l:1986802-2001341 Q9P2R3 5.11e-27 Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005765; GO:0005768; GO:0005769; GO:0005829; GO:0006897; GO:0010008; GO:0016020; GO:0016197; GO:0031267; GO:0034058; GO:0042147; GO:0043231; GO:0044354; GO:0046872; GO:0048549; GO:0070062; GO:0090160; GO:1901981 988 FUN_016137 1189 975 529 809 623 ptg000010l:1986802-2001341 Q9P2R3 5.11e-27 Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif) Homo sapiens (Human) endocytosis [GO:0006897]; endosomal transport [GO:0016197]; endosomal vesicle fusion [GO:0034058]; Golgi to lysosome transport [GO:0090160]; positive regulation of pinocytosis [GO:0048549]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005765; GO:0005768; GO:0005769; GO:0005829; GO:0006897; GO:0010008; GO:0016020; GO:0016197; GO:0031267; GO:0034058; GO:0042147; GO:0043231; GO:0044354; GO:0046872; GO:0048549; GO:0070062; GO:0090160; GO:1901981 989 FUN_016136 14 50 19 88 47 NA NA NA NA NA NA NA 990 FUN_016135 108 40 0 53 43 NA NA NA NA NA NA NA 991 FUN_009199 172 74 11 12 4 NA NA NA NA NA NA NA 992 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 6.75e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 993 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 1.24e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 994 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 1.83e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 995 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 4.21e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 996 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 3.64e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 997 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 8.46e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 998 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 6.4e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 999 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 4.24e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1000 FUN_009198 38 36 35 120 17 ptg000004l:3863688-3868964 Q96AY4 6.51e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1001 FUN_009191 325 141 30 119 40 NA NA NA NA NA NA NA 1002 FUN_009192 0 21 15 35 0 NA NA NA NA NA NA NA 1003 FUN_009195 368 415 27 196 36 NA NA NA NA NA NA NA 1004 FUN_009197 140 65 0 397 6 NA NA NA NA NA NA NA 1005 FUN_008823 17 24 0 14 97 NA NA NA NA NA NA NA 1006 FUN_008820 120 31 13 0 0 NA NA NA NA NA NA NA 1007 FUN_008821 16 32 4 31 32 NA NA NA NA NA NA NA 1008 FUN_008826 22 0 0 35 17 NA NA NA NA NA NA NA 1009 FUN_008824 14 28 12 25 39 NA NA NA NA NA NA NA 1010 FUN_008825 0 7 0 0 0 NA NA NA NA NA NA NA 1011 FUN_008828 0 0 0 0 18 NA NA NA NA NA NA NA 1012 FUN_026549 174 0 33 28 65 NA NA NA NA NA NA NA 1013 FUN_026548 1199 766 562 806 899 NA NA NA NA NA NA NA 1014 FUN_028521 0 4 7 38 23 NA NA NA NA NA NA NA 1015 FUN_028520 0 0 0 41 0 NA NA NA NA NA NA NA 1016 FUN_028523 0 0 0 0 14 NA NA NA NA NA NA NA 1017 FUN_026546 706 250 359 701 742 NA NA NA NA NA NA NA 1018 FUN_026540 1984 1428 831 1360 883 NA NA NA NA NA NA NA 1019 FUN_026543 2784 1029 2595 5272 3215 NA NA NA NA NA NA NA 1020 FUN_022048 417 111 113 442 276 ptg000016l:5021824-5049209 Q7TN88 1.58e-56 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1021 FUN_022048 417 111 113 442 276 ptg000016l:5021824-5049209 Q7TN88 4.08e-43 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1022 FUN_022044 1170 924 1019 1244 2633 NA NA NA NA NA NA NA 1023 FUN_022045 2400 1756 870 1938 1016 NA NA NA NA NA NA NA 1024 FUN_022040 519 174 362 838 668 NA NA NA NA NA NA NA 1025 FUN_022041 111 0 57 98 130 ptg000016l:4941743-4944582 Q91X17 4.33e-30 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 1026 FUN_022042 5117 4415 2014 5852 3238 ptg000016l:4950936-4953292 Q9H4G4 7.98e-22 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 1027 FUN_022043 1224 993 871 1410 2666 NA NA NA NA NA NA NA 1028 FUN_024947 4 1 0 0 17 NA NA NA NA NA NA NA 1029 FUN_024946 62 55 0 0 79 NA NA NA NA NA NA NA 1030 FUN_024945 54 34 0 0 58 NA NA NA NA NA NA NA 1031 FUN_024944 3081 2327 1213 3238 2298 NA NA NA NA NA NA NA 1032 FUN_024943 2156 1160 1027 1479 1634 NA NA NA NA NA NA NA 1033 FUN_024942 1547 829 572 678 583 NA NA NA NA NA NA NA 1034 FUN_024949 7 0 0 0 0 NA NA NA NA NA NA NA 1035 FUN_024948 3 17 0 0 13 NA NA NA NA NA NA NA 1036 FUN_044031 519 10977 2331 4050 3301 NA NA NA NA NA NA NA 1037 FUN_014198 3 0 2 0 59 NA NA NA NA NA NA NA 1038 FUN_022484 917 947 662 2262 1130 ptg000016l:9489607-9509222 Q9HCR9 1.21e-42 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (EC 3.1.4.35) (EC 3.1.4.53) (cAMP and cGMP phosphodiesterase 11A) Homo sapiens (Human) metabolic process [GO:0008152]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; signal transduction [GO:0007165] GO:0004112; GO:0004114; GO:0004115; GO:0004118; GO:0005829; GO:0007165; GO:0008152; GO:0010754; GO:0030553; GO:0043204; GO:0043951; GO:0046872; GO:0047555 1039 FUN_022486 4088 2395 1544 2457 1712 NA NA NA NA NA NA NA 1040 FUN_024126 883 483 421 379 303 NA NA NA NA NA NA NA 1041 FUN_044032 725 11825 11751 1188 4191 NA NA NA NA NA NA NA 1042 FUN_022481 3582 2916 1889 2866 2178 NA NA NA NA NA NA NA 1043 FUN_019472 2 0 0 7 17 NA NA NA NA NA NA NA 1044 FUN_022483 1160 857 802 1789 1232 NA NA NA NA NA NA NA 1045 FUN_019479 0 0 0 0 7 NA NA NA NA NA NA NA 1046 FUN_019478 0 0 12 0 8 NA NA NA NA NA NA NA 1047 FUN_038227 39 6 5 11 26 NA NA NA NA NA NA NA 1048 FUN_038226 187 44 189 105 281 ptg000027l:4427118-4432217 Q6IVV8 4.26e-46 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 1049 FUN_038225 111 43 54 120 55 ptg000027l:4420612-4426836 Q7Z442 7.54e-40 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1050 FUN_038224 99 37 83 87 73 NA NA NA NA NA NA NA 1051 FUN_038223 0 7 16 0 14 NA NA NA NA NA NA NA 1052 FUN_038222 65 0 60 0 111 NA NA NA NA NA NA NA 1053 FUN_038221 0 0 0 0 7 NA NA NA NA NA NA NA 1054 FUN_038220 2345 1882 681 1711 2040 NA NA NA NA NA NA NA 1055 FUN_027821 0 0 0 5 7 NA NA NA NA NA NA NA 1056 FUN_038229 257 107 215 246 186 ptg000027l:4467060-4498846 Q7Z442 5.83e-38 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 1057 FUN_038228 67 0 14 27 75 NA NA NA NA NA NA NA 1058 FUN_039574 0 168 47 0 228 NA NA NA NA NA NA NA 1059 FUN_039575 0 10 0 4 13 NA NA NA NA NA NA NA 1060 FUN_039576 14 985 805 0 1905 NA NA NA NA NA NA NA 1061 FUN_039570 0 0 0 0 14 NA NA NA NA NA NA NA 1062 FUN_039571 14 0 0 5 8 NA NA NA NA NA NA NA 1063 FUN_039572 3 30 0 134 26 NA NA NA NA NA NA NA 1064 FUN_039573 565 1505 1239 10 3617 ptg000030l:1396599-1411122 Q5DU56 4.8e-38 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1065 FUN_039573 565 1505 1239 10 3617 ptg000030l:1396599-1411122 Q5DU56 1.68e-35 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1066 FUN_039573 565 1505 1239 10 3617 ptg000030l:1396599-1411122 Q5DU56 3.14e-35 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1067 FUN_039573 565 1505 1239 10 3617 ptg000030l:1396599-1411122 Q5DU56 1.66e-23 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1068 FUN_039578 33 17 52 183 37 NA NA NA NA NA NA NA 1069 FUN_022489 218 169 106 203 236 NA NA NA NA NA NA NA 1070 FUN_024055 295 230 139 233 321 NA NA NA NA NA NA NA 1071 FUN_024054 499 311 258 574 439 ptg000018l:1772219-1777415 Q80T69 5.02e-60 Lysine-specific demethylase 9 (KDM9) (EC 1.14.11.-) (Round spermatid basic protein 1) (Rosbin) Mus musculus (Mouse) chromatin organization [GO:0006325] GO:0005634; GO:0006325; GO:0035575; GO:0046872 1072 FUN_024054 499 311 258 574 439 ptg000018l:1772219-1777415 Q80T69 5.64e-21 Lysine-specific demethylase 9 (KDM9) (EC 1.14.11.-) (Round spermatid basic protein 1) (Rosbin) Mus musculus (Mouse) chromatin organization [GO:0006325] GO:0005634; GO:0006325; GO:0035575; GO:0046872 1073 FUN_024057 20 8 17 36 14 NA NA NA NA NA NA NA 1074 FUN_024056 47 71 29 76 65 NA NA NA NA NA NA NA 1075 FUN_024051 1824 2724 1837 2712 2739 NA NA NA NA NA NA NA 1076 FUN_024050 321 248 176 360 306 NA NA NA NA NA NA NA 1077 FUN_024053 4848 3120 2816 5584 3770 NA NA NA NA NA NA NA 1078 FUN_012143 15 44 7 150 5 NA NA NA NA NA NA NA 1079 FUN_024059 4319 3201 1726 4175 1896 NA NA NA NA NA NA NA 1080 FUN_024058 1019 572 361 855 290 NA NA NA NA NA NA NA 1081 FUN_012141 313 401 535 337 220 NA NA NA NA NA NA NA 1082 FUN_012144 1746 2869 2161 2832 1605 ptg000008l:5637522-5638563 Q9GRC0 1.65e-69 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 1083 FUN_012145 1925 1748 1572 2009 1752 NA NA NA NA NA NA NA 1084 FUN_022728 22 5 13 7 26 ptg000016l:12686939-12687825 P25291 9.53e-28 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 1085 FUN_035237 10392 7323 4181 5398 4048 NA NA NA NA NA NA NA 1086 FUN_038483 17 0 6 0 33 NA NA NA NA NA NA NA 1087 FUN_038482 3199 5953 1299 4863 2479 NA NA NA NA NA NA NA 1088 FUN_038481 0 0 27 0 48 NA NA NA NA NA NA NA 1089 FUN_038480 194 39 2 79 71 NA NA NA NA NA NA NA 1090 FUN_038487 1764 2557 614 952 998 NA NA NA NA NA NA NA 1091 FUN_038486 51 20 20 3 15 NA NA NA NA NA NA NA 1092 FUN_038485 0 51 46 31 71 NA NA NA NA NA NA NA 1093 FUN_038484 2973 2532 1007 1995 904 NA NA NA NA NA NA NA 1094 FUN_038489 967 1084 1329 954 467 ptg000027l:7864578-7879629 Q9BX70 1.41e-61 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 1095 FUN_038488 1498 1184 586 1071 928 NA NA NA NA NA NA NA 1096 FUN_031761 169 125 25 156 58 NA NA NA NA NA NA NA 1097 FUN_031760 283 501 198 455 170 NA NA NA NA NA NA NA 1098 FUN_031763 181 160 2507 13 0 NA NA NA NA NA NA NA 1099 FUN_031762 0 0 17 0 103 NA NA NA NA NA NA NA 1100 FUN_031765 0 0 44 0 0 NA NA NA NA NA NA NA 1101 FUN_031764 0 28 26 0 0 NA NA NA NA NA NA NA 1102 FUN_031767 0 8 0 0 0 NA NA NA NA NA NA NA 1103 FUN_031766 8 6 7 3 19 NA NA NA NA NA NA NA 1104 FUN_031769 0 254 287 0 9 NA NA NA NA NA NA NA 1105 FUN_031768 0 154 84 0 0 NA NA NA NA NA NA NA 1106 FUN_038093 2575 2094 1644 856 39 NA NA NA NA NA NA NA 1107 FUN_003513 0 7 25 282 98 NA NA NA NA NA NA NA 1108 FUN_018153 37 3 0 190 90 NA NA NA NA NA NA NA 1109 FUN_008224 8 2 24 0 0 NA NA NA NA NA NA NA 1110 FUN_039689 0 14 0 16 29 NA NA NA NA NA NA NA 1111 FUN_039686 11 0 0 0 0 NA NA NA NA NA NA NA 1112 FUN_039687 0 0 2 0 12 NA NA NA NA NA NA NA 1113 FUN_039682 24 2 2 13 11 NA NA NA NA NA NA NA 1114 FUN_039683 8 0 3 0 11 NA NA NA NA NA NA NA 1115 FUN_039680 0 0 112 0 0 NA NA NA NA NA NA NA 1116 FUN_039681 8 0 0 17 5 NA NA NA NA NA NA NA 1117 FUN_027083 45 7 32 42 47 NA NA NA NA NA NA NA 1118 FUN_027081 0 0 3 16 8 NA NA NA NA NA NA NA 1119 FUN_027087 0 0 36 16 43 ptg000020l:16637579-16639241 Q9GZV8 4.39e-102 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Homo sapiens (Human) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000902; GO:0000977; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0030718; GO:0031490; GO:0034972; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 1120 FUN_027086 3298 3277 1352 3380 4546 ptg000020l:16604073-16630810 Q14562 2.02e-106 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006396; GO:0008380; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 1121 FUN_027086 3298 3277 1352 3380 4546 ptg000020l:16604073-16630810 Q14562 1.35e-57 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006396; GO:0008380; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 1122 FUN_027086 3298 3277 1352 3380 4546 ptg000020l:16604073-16630810 Q14562 9.59e-28 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006396; GO:0008380; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 1123 FUN_027086 3298 3277 1352 3380 4546 ptg000020l:16604073-16630810 Q14562 1.03e-26 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006396; GO:0008380; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 1124 FUN_027086 3298 3277 1352 3380 4546 ptg000020l:16604073-16630810 Q14562 9.89e-25 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006396; GO:0008380; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 1125 FUN_027086 3298 3277 1352 3380 4546 ptg000020l:16604073-16630810 Q14562 2.59e-23 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (DEAH box protein 8) (RNA helicase HRH1) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA processing [GO:0006396]; RNA splicing [GO:0008380]; spliceosomal complex disassembly [GO:0000390] GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0006396; GO:0008380; GO:0016604; GO:0016887; GO:0042802; GO:0071007; GO:0071013 1126 FUN_027085 361 300 109 219 253 NA NA NA NA NA NA NA 1127 FUN_027084 6877 0 0 0 5178 NA NA NA NA NA NA NA 1128 FUN_027089 4 8 9 31 15 NA NA NA NA NA NA NA 1129 FUN_027088 0 0 20 0 0 NA NA NA NA NA NA NA 1130 FUN_026975 0 6 17 0 0 NA NA NA NA NA NA NA 1131 FUN_026976 1657 953 908 1462 1488 ptg000020l:15417897-15424656 Q9JL04 1.68e-21 Formin-2 Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin nucleation [GO:0045010]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; homologous chromosome movement towards spindle pole in meiosis I anaphase [GO:0051758]; intracellular transport [GO:0046907]; meiotic chromosome movement towards spindle pole [GO:0016344]; negative regulation of apoptotic process [GO:0043066]; negative regulation of protein catabolic process [GO:0042177]; oogenesis [GO:0048477]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003779; GO:0005634; GO:0005730; GO:0005737; GO:0005783; GO:0005789; GO:0005819; GO:0005829; GO:0005884; GO:0005886; GO:0005902; GO:0005938; GO:0006974; GO:0008017; GO:0015031; GO:0015629; GO:0016192; GO:0016344; GO:0016477; GO:0030659; GO:0031532; GO:0040038; GO:0042177; GO:0043066; GO:0045010; GO:0046907; GO:0048471; GO:0048477; GO:0051017; GO:0051295; GO:0051758; GO:0070649; GO:0071456; GO:2000781 1132 FUN_026977 0 9 0 5 0 NA NA NA NA NA NA NA 1133 FUN_026972 0 41 120 0 4 ptg000020l:15369752-15373674 O55171 8.74e-35 Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (ARTISt/p43) (Acyl coenzyme A thioester hydrolase) (MTE-I) (Very-long-chain acyl-CoA thioesterase) Rattus norvegicus (Rat) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; response to epidermal growth factor [GO:0070849]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to nutrient levels [GO:0031667]; response to xenobiotic stimulus [GO:0009410]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001666; GO:0001676; GO:0005739; GO:0005759; GO:0006631; GO:0006637; GO:0009410; GO:0009725; GO:0016290; GO:0031667; GO:0042760; GO:0047617; GO:0070849; GO:0102991 1134 FUN_026972 0 41 120 0 4 ptg000020l:15369752-15373674 O55171 1.32e-21 Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (ARTISt/p43) (Acyl coenzyme A thioester hydrolase) (MTE-I) (Very-long-chain acyl-CoA thioesterase) Rattus norvegicus (Rat) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; response to epidermal growth factor [GO:0070849]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to nutrient levels [GO:0031667]; response to xenobiotic stimulus [GO:0009410]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001666; GO:0001676; GO:0005739; GO:0005759; GO:0006631; GO:0006637; GO:0009410; GO:0009725; GO:0016290; GO:0031667; GO:0042760; GO:0047617; GO:0070849; GO:0102991 1135 FUN_026978 3687 2622 1554 2680 1880 NA NA NA NA NA NA NA 1136 FUN_026979 0 0 0 2 57 NA NA NA NA NA NA NA 1137 FUN_018150 6 10 13 67 15 ptg000012l:4948915-4959318 Q9UEW3 8.55e-25 Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898] GO:0001540; GO:0001664; GO:0001934; GO:0004888; GO:0005044; GO:0005581; GO:0005737; GO:0005886; GO:0006897; GO:0006898; GO:0006911; GO:0007166; GO:0007193; GO:0030666; GO:0038024; GO:0038187; GO:0043277; GO:0045087; GO:0070374; GO:0097242 1138 FUN_037888 85 158 148 174 447 NA NA NA NA NA NA NA 1139 FUN_040443 700 762 358 602 605 NA NA NA NA NA NA NA 1140 FUN_037882 50 0 87 154 0 NA NA NA NA NA NA NA 1141 FUN_037359 0 0 0 10 0 NA NA NA NA NA NA NA 1142 FUN_037357 3 0 9 31 0 NA NA NA NA NA NA NA 1143 FUN_037354 1929 1570 8 3 556 NA NA NA NA NA NA NA 1144 FUN_037355 1415 954 0 0 512 NA NA NA NA NA NA NA 1145 FUN_037352 0 0 0 0 74 NA NA NA NA NA NA NA 1146 FUN_037353 7407 6434 21 40 3814 NA NA NA NA NA NA NA 1147 FUN_037351 18 0 0 0 0 NA NA NA NA NA NA NA 1148 FUN_005478 6 12 0 17 24 NA NA NA NA NA NA NA 1149 FUN_005479 3084 2026 1674 2859 2920 ntLink_8:35963987-35995916 P50904 1.06e-38 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 1150 FUN_005479 3084 2026 1674 2859 2920 ntLink_8:35963987-35995916 P50904 1.06e-38 Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; activation of GTPase activity [GO:0090630]; blood vessel morphogenesis [GO:0048514]; cell adhesion [GO:0007155]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; male genitalia development [GO:0030539]; mitotic cytokinesis [GO:0000281]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of glucose import [GO:0046326]; positive regulation of GTPase activity [GO:0043547]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; regulation of actin filament polymerization [GO:0030833]; response to insulin [GO:0032868]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculogenesis [GO:0001570] GO:0000281; GO:0001570; GO:0001726; GO:0001784; GO:0001934; GO:0001953; GO:0005096; GO:0005102; GO:0005161; GO:0005829; GO:0005886; GO:0007155; GO:0007162; GO:0007165; GO:0009410; GO:0016020; GO:0030036; GO:0030539; GO:0030833; GO:0030971; GO:0031965; GO:0032868; GO:0036120; GO:0043066; GO:0043422; GO:0043524; GO:0043547; GO:0044325; GO:0044344; GO:0044877; GO:0046326; GO:0048146; GO:0048514; GO:0050731; GO:0051020; GO:0071364; GO:0090630; GO:1990782 1151 FUN_005476 3229 2470 1479 1780 1731 NA NA NA NA NA NA NA 1152 FUN_005477 0 0 12 0 0 NA NA NA NA NA NA NA 1153 FUN_005474 1186 1035 976 1404 1563 NA NA NA NA NA NA NA 1154 FUN_005475 0 40 0 0 0 NA NA NA NA NA NA NA 1155 FUN_005472 43 15 42 41 15 NA NA NA NA NA NA NA 1156 FUN_018652 281 57 309 222 53 NA NA NA NA NA NA NA 1157 FUN_005470 8338 10649 4521 8052 4276 NA NA NA NA NA NA NA 1158 FUN_005471 109 217 94 199 113 NA NA NA NA NA NA NA 1159 FUN_018222 73 14 87 109 222 NA NA NA NA NA NA NA 1160 FUN_018653 149 35 121 71 12 ptg000012l:11530875-11544487 Q09575 5.2e-53 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 1161 FUN_018653 149 35 121 71 12 ptg000012l:11530875-11544487 Q09575 5.2e-53 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 1162 FUN_018653 149 35 121 71 12 ptg000012l:11530875-11544487 Q09575 3.28e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 1163 FUN_001508 592 306 280 261 354 ntLink_6:13096837-13100145 Q925F4 2.77e-28 RING finger protein 37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RNF37) (U-box domain-containing protein 5) (UbcM4-interacting protein 5) Mus musculus (Mouse) protein polyubiquitination [GO:0000209] GO:0000209; GO:0005634; GO:0005654; GO:0005925; GO:0016604; GO:0031625; GO:0034450; GO:0046872; GO:0061630 1164 FUN_001509 36 43 56 34 38 NA NA NA NA NA NA NA 1165 FUN_001506 1020 1119 610 999 817 NA NA NA NA NA NA NA 1166 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 1.36e-92 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1167 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 1.16e-69 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1168 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 9.58e-41 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1169 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 1.97e-30 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1170 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 3.23e-28 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1171 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 3.17e-27 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1172 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 5.59e-27 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1173 FUN_001504 3677 2702 2061 4091 3917 ntLink_6:13057130-13071329 Q8CFI7 1.25e-25 DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0000781; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0006366; GO:0032549; GO:0046872 1174 FUN_001505 615 559 437 657 322 NA NA NA NA NA NA NA 1175 FUN_001502 0 0 0 0 83 NA NA NA NA NA NA NA 1176 FUN_001503 13903 3266 3359 9826 10103 NA NA NA NA NA NA NA 1177 FUN_001500 1074 395 129 1131 1070 NA NA NA NA NA NA NA 1178 FUN_017607 0 0 0 0 6 NA NA NA NA NA NA NA 1179 FUN_018656 834 471 158 619 396 NA NA NA NA NA NA NA 1180 FUN_026028 62 0 39 17 14 NA NA NA NA NA NA NA 1181 FUN_026029 63 0 13 11 0 NA NA NA NA NA NA NA 1182 FUN_026023 39519 15786 19064 60476 51460 ptg000020l:3647247-3714965 Q94K49 2.91e-26 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 1183 FUN_026020 236 370 142 1374 806 NA NA NA NA NA NA NA 1184 FUN_026021 1406 1118 448 3824 3222 NA NA NA NA NA NA NA 1185 FUN_026026 20 10 16 0 15 ptg000020l:3866075-3870716 P50222 5.08e-26 Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2) Homo sapiens (Human) angiogenesis [GO:0001525]; limb development [GO:0060173]; negative regulation of cell migration involved in sprouting angiogenesis [GO:0090051]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; skeletal muscle tissue development [GO:0007519]; somite development [GO:0061053]; somite specification [GO:0001757] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0001757; GO:0003700; GO:0005634; GO:0005737; GO:0006357; GO:0007519; GO:0016607; GO:0043565; GO:0045944; GO:0060021; GO:0060173; GO:0061053; GO:0090051; GO:1990837 1186 FUN_026027 171 41 0 164 106 ptg000020l:3875866-3879107 A2T7T2 1.88e-27 Homeobox protein MOX-1 (Mesenchyme homeobox 1) Pongo pygmaeus (Bornean orangutan) hematopoietic stem cell differentiation [GO:0060218]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sclerotome development [GO:0061056]; somite development [GO:0061053] GO:0000981; GO:0003700; GO:0005634; GO:0005737; GO:0043565; GO:0045944; GO:0060218; GO:0061053; GO:0061056 1187 FUN_026024 32145 12687 13925 57592 49217 NA NA NA NA NA NA NA 1188 FUN_026025 1311 1214 727 1769 900 ptg000020l:3846675-3860323 P93107 3.41e-22 Flagellar WD repeat-containing protein Pf20 Chlamydomonas reinhardtii (Chlamydomonas smithii) NA GO:0031514 1189 FUN_007830 273 42 94 235 196 ptg000002l:5167914-5174752 Q8K3Z0 2.8e-32 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 1190 FUN_007831 4041 1942 2294 2859 3542 ptg000002l:5178106-5203980 Q98UF7 1.48e-41 Pecanex-like protein 1 (Pecanex homolog protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) NA GO:0016020 1191 FUN_007831 4041 1942 2294 2859 3542 ptg000002l:5178106-5203980 Q98UF7 5.03e-33 Pecanex-like protein 1 (Pecanex homolog protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) NA GO:0016020 1192 FUN_007831 4041 1942 2294 2859 3542 ptg000002l:5178106-5203980 Q98UF7 6.66e-29 Pecanex-like protein 1 (Pecanex homolog protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) NA GO:0016020 1193 FUN_007831 4041 1942 2294 2859 3542 ptg000002l:5178106-5203980 Q98UF7 2.14e-21 Pecanex-like protein 1 (Pecanex homolog protein 1) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) NA GO:0016020 1194 FUN_007832 1860 1438 1314 1059 940 NA NA NA NA NA NA NA 1195 FUN_007833 308 196 229 262 186 NA NA NA NA NA NA NA 1196 FUN_007834 10286 8392 7026 12259 10131 NA NA NA NA NA NA NA 1197 FUN_007835 51 1 66 6 229 NA NA NA NA NA NA NA 1198 FUN_007836 3675 1529 1810 2523 2284 ptg000002l:5238518-5257719 Q5ND34 2.98e-108 WD repeat-containing protein 81 Mus musculus (Mouse) aggrephagy [GO:0035973]; early endosome to late endosome transport [GO:0045022]; mitochondrion organization [GO:0007005]; protein stabilization [GO:0050821]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000421; GO:0005739; GO:0005765; GO:0005829; GO:0006511; GO:0007005; GO:0031313; GO:0031901; GO:0031902; GO:0035014; GO:0035973; GO:0043551; GO:0045022; GO:0050821; GO:0070530 1199 FUN_007837 2067 2635 1887 1645 949 ptg000002l:5259052-5259943 Q1L9A2 1.33e-22 Optic atrophy 3 protein homolog Danio rerio (Zebrafish) (Brachydanio rerio) locomotory behavior [GO:0007626]; musculoskeletal movement [GO:0050881]; regulation of buoyancy [GO:0031413]; regulation of lipid metabolic process [GO:0019216] GO:0005739; GO:0007626; GO:0019216; GO:0031413; GO:0050881 1200 FUN_007838 120 72 99 167 99 NA NA NA NA NA NA NA 1201 FUN_007839 2501 1962 1520 2953 2113 NA NA NA NA NA NA NA 1202 FUN_031422 1953 435 700 1152 731 ptg000023l:21002538-21015482 Q7RTR2 8.96e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1203 FUN_031422 1953 435 700 1152 731 ptg000023l:21002538-21015482 Q7RTR2 8.96e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1204 FUN_031422 1953 435 700 1152 731 ptg000023l:21002538-21015482 Q7RTR2 9.83e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1205 FUN_031422 1953 435 700 1152 731 ptg000023l:21002538-21015482 Q7RTR2 9.83e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1206 FUN_031422 1953 435 700 1152 731 ptg000023l:21002538-21015482 Q7RTR2 3.46e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1207 FUN_031422 1953 435 700 1152 731 ptg000023l:21002538-21015482 Q7RTR2 4.76e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 1208 FUN_016261 3 0 0 0 31 NA NA NA NA NA NA NA 1209 FUN_016260 55 32 19 160 128 NA NA NA NA NA NA NA 1210 FUN_034078 12 0 0 11 24 NA NA NA NA NA NA NA 1211 FUN_018468 0 0 0 28 8 NA NA NA NA NA NA NA 1212 FUN_034076 98 140 80 270 66 NA NA NA NA NA NA NA 1213 FUN_018465 771 594 390 637 543 NA NA NA NA NA NA NA 1214 FUN_004170 72929 83348 84795 83132 30018 NA NA NA NA NA NA NA 1215 FUN_004171 2149 2149 1362 2393 2057 ntLink_8:20106414-20142052 Q865S1 1.52e-27 AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (BLVPCP1) (Bovine leukemia virus cell receptor) (BLV-R) (Delta-adaptin) Bos taurus (Bovine) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; Golgi to vacuole transport [GO:0006896]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; protein targeting to vacuole [GO:0006623]; synaptic vesicle budding from endosome [GO:0016182]; synaptic vesicle membrane organization [GO:0048499] GO:0000139; GO:0006623; GO:0006896; GO:0008089; GO:0010008; GO:0016182; GO:0030123; GO:0043195; GO:0048490; GO:0048499; GO:0098830; GO:0098943; GO:1904115 1216 FUN_004171 2149 2149 1362 2393 2057 ntLink_8:20106414-20142052 Q865S1 1.52e-27 AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (BLVPCP1) (Bovine leukemia virus cell receptor) (BLV-R) (Delta-adaptin) Bos taurus (Bovine) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; Golgi to vacuole transport [GO:0006896]; neurotransmitter receptor transport, postsynaptic endosome to lysosome [GO:0098943]; protein targeting to vacuole [GO:0006623]; synaptic vesicle budding from endosome [GO:0016182]; synaptic vesicle membrane organization [GO:0048499] GO:0000139; GO:0006623; GO:0006896; GO:0008089; GO:0010008; GO:0016182; GO:0030123; GO:0043195; GO:0048490; GO:0048499; GO:0098830; GO:0098943; GO:1904115 1217 FUN_003784 23 0 7 0 0 NA NA NA NA NA NA NA 1218 FUN_003785 4 0 8 9 24 NA NA NA NA NA NA NA 1219 FUN_038195 449 651 305 1092 1193 NA NA NA NA NA NA NA 1220 FUN_004175 0 0 0 0 67 NA NA NA NA NA NA NA 1221 FUN_003780 150 92 0 0 0 NA NA NA NA NA NA NA 1222 FUN_004177 22 0 23 0 87 NA NA NA NA NA NA NA 1223 FUN_004657 1552 1587 1013 1849 1046 ntLink_8:25425240-25448284 P21575 1.29e-28 Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain) Rattus norvegicus (Rat) endocytosis [GO:0006897]; endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; toxin transport [GO:1901998] GO:0001917; GO:0002031; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006897; GO:0006898; GO:0007032; GO:0008017; GO:0008021; GO:0008022; GO:0016020; GO:0016185; GO:0017124; GO:0019901; GO:0030117; GO:0031623; GO:0031749; GO:0032991; GO:0042802; GO:0043196; GO:0044877; GO:0045202; GO:0048488; GO:0050804; GO:0050998; GO:0098684; GO:0098793; GO:0098835; GO:0098978; GO:0120283; GO:1900242; GO:1900244; GO:1901998; GO:1903423; GO:1904645 1224 FUN_004657 1552 1587 1013 1849 1046 ntLink_8:25425240-25448284 P21575 2.02e-23 Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain) Rattus norvegicus (Rat) endocytosis [GO:0006897]; endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; toxin transport [GO:1901998] GO:0001917; GO:0002031; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006897; GO:0006898; GO:0007032; GO:0008017; GO:0008021; GO:0008022; GO:0016020; GO:0016185; GO:0017124; GO:0019901; GO:0030117; GO:0031623; GO:0031749; GO:0032991; GO:0042802; GO:0043196; GO:0044877; GO:0045202; GO:0048488; GO:0050804; GO:0050998; GO:0098684; GO:0098793; GO:0098835; GO:0098978; GO:0120283; GO:1900242; GO:1900244; GO:1901998; GO:1903423; GO:1904645 1225 FUN_004657 1552 1587 1013 1849 1046 ntLink_8:25425240-25448284 P21575 2.02e-23 Dynamin-1 (EC 3.6.5.5) (B-dynamin) (D100) (Dynamin, brain) Rattus norvegicus (Rat) endocytosis [GO:0006897]; endosome organization [GO:0007032]; G protein-coupled receptor internalization [GO:0002031]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of synaptic vesicle recycling [GO:1903423]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of synaptic vesicle endocytosis [GO:1900242]; response to amyloid-beta [GO:1904645]; synaptic vesicle budding from presynaptic endocytic zone membrane [GO:0016185]; synaptic vesicle endocytosis [GO:0048488]; toxin transport [GO:1901998] GO:0001917; GO:0002031; GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006897; GO:0006898; GO:0007032; GO:0008017; GO:0008021; GO:0008022; GO:0016020; GO:0016185; GO:0017124; GO:0019901; GO:0030117; GO:0031623; GO:0031749; GO:0032991; GO:0042802; GO:0043196; GO:0044877; GO:0045202; GO:0048488; GO:0050804; GO:0050998; GO:0098684; GO:0098793; GO:0098835; GO:0098978; GO:0120283; GO:1900242; GO:1900244; GO:1901998; GO:1903423; GO:1904645 1226 FUN_031178 0 18 0 0 0 NA NA NA NA NA NA NA 1227 FUN_003397 0 0 16 0 57 NA NA NA NA NA NA NA 1228 FUN_043320 218 87 128 286 534 NA NA NA NA NA NA NA 1229 FUN_007167 64 101 53 67 205 ptg000001l:21201516-21202899 F1R8P4 9.7e-28 Glycine receptor subunit alpha-2 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004888; GO:0005254; GO:0016594; GO:0016933; GO:0022824; GO:0034707; GO:0042995; GO:0045211; GO:0046872 1230 FUN_043322 3467 1476 1204 2252 1508 ptg000047l:7071770-7083117 Q03146 5.36e-69 Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (Protein-tyrosine kinase MPK-6) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) Mus musculus (Mouse) axon development [GO:0061564]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell population proliferation [GO:0008283]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; ear development [GO:0043583]; embryo implantation [GO:0007566]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of cell population proliferation [GO:0008285]; neuron projection extension [GO:1990138]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of cell growth [GO:0001558]; regulation of cell-matrix adhesion [GO:0001952]; regulation of extracellular matrix disassembly [GO:0010715]; smooth muscle cell migration [GO:0014909]; smooth muscle cell-matrix adhesion [GO:0061302]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; wound healing, spreading of cells [GO:0044319] GO:0001558; GO:0001952; GO:0004714; GO:0005518; GO:0005524; GO:0005737; GO:0005886; GO:0005903; GO:0007169; GO:0007566; GO:0007595; GO:0008283; GO:0008285; GO:0010715; GO:0014909; GO:0016323; GO:0018108; GO:0033674; GO:0038062; GO:0038063; GO:0038083; GO:0043235; GO:0043583; GO:0044319; GO:0046777; GO:0046872; GO:0060444; GO:0060749; GO:0061302; GO:0061564; GO:1990138 1231 FUN_043323 5681 8331 2044 2965 2838 NA NA NA NA NA NA NA 1232 FUN_043324 212 108 82 171 126 ptg000047l:7093034-7098423 P23034 4.93e-48 Aspartate aminotransferase (AspAT) (EC 2.6.1.1) (Transaminase A) Bacillus sp. (strain YM-2) biosynthetic process [GO:0009058] GO:0004069; GO:0005737; GO:0009058; GO:0030170 1233 FUN_043325 1590 959 730 2041 1741 NA NA NA NA NA NA NA 1234 FUN_043326 6004 3148 2660 6398 4533 NA NA NA NA NA NA NA 1235 FUN_007161 2644 2012 1648 3539 2837 NA NA NA NA NA NA NA 1236 FUN_043328 380 8 23 80 48 NA NA NA NA NA NA NA 1237 FUN_043329 16 153 186 236 208 NA NA NA NA NA NA NA 1238 FUN_007168 65 47 48 54 119 NA NA NA NA NA NA NA 1239 FUN_007169 1502 609 605 1358 1422 NA NA NA NA NA NA NA 1240 FUN_005995 2150 1536 934 1685 2213 ptg000001l:6554607-6566718 A7RNG8 3.79e-27 Coiled-coil domain-containing protein 22 homolog Nematostella vectensis (Starlet sea anemone) positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060] GO:0097602; GO:2000060 1241 FUN_005995 2150 1536 934 1685 2213 ptg000001l:6554607-6566718 A7RNG8 3.79e-27 Coiled-coil domain-containing protein 22 homolog Nematostella vectensis (Starlet sea anemone) positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060] GO:0097602; GO:2000060 1242 FUN_005994 1016 1308 1220 1615 1426 NA NA NA NA NA NA NA 1243 FUN_005997 234 172 126 278 262 ptg000001l:6604226-6606416 P23780 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Mus musculus (Mouse) cellular carbohydrate metabolic process [GO:0044262]; galactose catabolic process [GO:0019388]; response to cortisone [GO:0051413]; response to Thyroglobulin triiodothyronine [GO:1904016] GO:0004565; GO:0005615; GO:0005737; GO:0005764; GO:0005773; GO:0005794; GO:0016787; GO:0016936; GO:0019388; GO:0042803; GO:0043231; GO:0044262; GO:0051413; GO:1904016 1244 FUN_005996 3857 5155 3005 2645 1565 ptg000001l:6568665-6588674 P10401 4.29e-38 Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0015074; GO:0042575 1245 FUN_005996 3857 5155 3005 2645 1565 ptg000001l:6568665-6588674 P10401 4.29e-38 Retrovirus-related Pol polyprotein from transposon gypsy [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0015074; GO:0042575 1246 FUN_019738 12 0 3 0 50 NA NA NA NA NA NA NA 1247 FUN_019739 0 0 0 0 35 NA NA NA NA NA NA NA 1248 FUN_005993 119 241 99 230 49 ptg000001l:6539784-6540969 Q91175 5.26e-39 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 1249 FUN_005992 1390 1464 1126 2016 1108 ptg000001l:6527737-6538561 P50429 1.45e-21 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 1250 FUN_019734 0 0 0 0 11 NA NA NA NA NA NA NA 1251 FUN_019736 2 9 3 0 11 NA NA NA NA NA NA NA 1252 FUN_019737 0 0 0 3 11 NA NA NA NA NA NA NA 1253 FUN_005999 6004 4103 3279 6064 4063 ptg000001l:6618918-6647450 O43602 2.72e-37 Neuronal migration protein doublecortin (Doublin) (Lissencephalin-X) (Lis-X) Homo sapiens (Human) axoneme assembly [GO:0035082]; central nervous system development [GO:0007417]; intracellular signal transduction [GO:0035556]; nervous system development [GO:0007399]; neuron migration [GO:0001764]; photoreceptor cell development [GO:0042461]; retina development in camera-type eye [GO:0060041] GO:0001764; GO:0005829; GO:0005856; GO:0005874; GO:0005875; GO:0005930; GO:0007399; GO:0007417; GO:0008017; GO:0019901; GO:0035082; GO:0035556; GO:0042461; GO:0043005; GO:0060041 1254 FUN_019732 4 10 11 7 12 NA NA NA NA NA NA NA 1255 FUN_019733 1 2 0 0 18 NA NA NA NA NA NA NA 1256 FUN_034731 46 0 4 21 10 NA NA NA NA NA NA NA 1257 FUN_034928 0 18 0 9 26 NA NA NA NA NA NA NA 1258 FUN_034929 52 2 36 29 36 ptg000025l:1885509-1886373 P28347 1.01e-41 Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13) Homo sapiens (Human) embryonic organ development [GO:0048568]; hippo signaling [GO:0035329]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein-containing complex assembly [GO:0065003]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0030307; GO:0035329; GO:0045893; GO:0045944; GO:0048568; GO:0065003; GO:0140552; GO:1902895; GO:1990837 1259 FUN_034924 0 55 23 81 37 NA NA NA NA NA NA NA 1260 FUN_034925 237 162 47 93 300 NA NA NA NA NA NA NA 1261 FUN_034926 275 74 28 39 141 NA NA NA NA NA NA NA 1262 FUN_034927 0 18 14 13 7 NA NA NA NA NA NA NA 1263 FUN_034920 552 144 210 130 359 NA NA NA NA NA NA NA 1264 FUN_034921 178 43 6 338 40 NA NA NA NA NA NA NA 1265 FUN_034922 970 645 766 675 769 NA NA NA NA NA NA NA 1266 FUN_034923 5630 777 67 1175 726 ptg000025l:1824007-1829900 B8WI85 1.19e-69 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 1267 FUN_034923 5630 777 67 1175 726 ptg000025l:1824007-1829900 B8WI85 2.34e-53 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 1268 FUN_034923 5630 777 67 1175 726 ptg000025l:1824007-1829900 B8WI85 6.15e-49 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 1269 FUN_034923 5630 777 67 1175 726 ptg000025l:1824007-1829900 B8WI85 5.11e-27 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 1270 FUN_036564 440 0 242 6 25 ptg000025l:19736218-19844604 P04323 5.21e-67 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 1271 FUN_036564 440 0 242 6 25 ptg000025l:19736218-19844604 P04323 1.5e-24 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 1272 FUN_036562 0 0 0 0 8 NA NA NA NA NA NA NA 1273 FUN_036563 60 64 15 51 11 ptg000025l:19722425-19724678 P83852 6.53e-88 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 1274 FUN_036561 11 0 8 0 7 NA NA NA NA NA NA NA 1275 FUN_002076 454 600 449 650 307 NA NA NA NA NA NA NA 1276 FUN_002074 34 0 87 0 149 NA NA NA NA NA NA NA 1277 FUN_002073 376 272 107 68 82 NA NA NA NA NA NA NA 1278 FUN_002072 16 0 0 4 19 NA NA NA NA NA NA NA 1279 FUN_002070 73 220 203 91 210 NA NA NA NA NA NA NA 1280 FUN_002079 3394 2908 1290 2178 2072 NA NA NA NA NA NA NA 1281 FUN_042051 1450 1367 1327 1398 2035 NA NA NA NA NA NA NA 1282 FUN_042050 3213 2210 785 1191 1063 ptg000035l:10084787-10088035 Q924M7 1.68e-22 Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) Mus musculus (Mouse) GDP-mannose biosynthetic process [GO:0009298]; glycolytic process from mannose through fructose-6-phosphate [GO:0061619]; mannose to fructose-6-phosphate metabolic process [GO:0061611] GO:0004476; GO:0005829; GO:0008270; GO:0009298; GO:0061611; GO:0061619 1283 FUN_042053 3999 3480 3367 3354 4285 NA NA NA NA NA NA NA 1284 FUN_042052 445 344 355 405 382 ptg000035l:10100859-10102858 Q0P4H0 3.09e-43 tRNA-specific adenosine deaminase 2 (EC 3.5.4.33) (Deaminase domain-containing protein 1) (tRNA-specific adenosine-34 deaminase subunit ADAT2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA wobble adenosine to inosine editing [GO:0002100] GO:0002100; GO:0008251; GO:0008270 1285 FUN_042055 28 94 19 51 179 NA NA NA NA NA NA NA 1286 FUN_042054 470 410 364 6 298 NA NA NA NA NA NA NA 1287 FUN_042056 0 66 0 0 0 NA NA NA NA NA NA NA 1288 FUN_042059 82 83 36 97 40 ptg000036l:11943-13380 Q9SR22 1.23e-69 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 1289 FUN_042058 852 394 345 816 832 NA NA NA NA NA NA NA 1290 FUN_014669 2363 2420 2416 2534 1540 NA NA NA NA NA NA NA 1291 FUN_023349 0 0 29 5 21 NA NA NA NA NA NA NA 1292 FUN_042589 351 168 81 105 59 ptg000039l:68381-76291 P48547 3.91e-50 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 1293 FUN_042588 202 307 129 219 241 ptg000039l:52530-60293 P48547 3.61e-50 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 1294 FUN_042588 202 307 129 219 241 ptg000039l:52530-60293 P48547 1.55e-34 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 1295 FUN_042583 740 621 333 740 651 NA NA NA NA NA NA NA 1296 FUN_042582 2472 1648 1005 1987 1861 ptg000039l:10063-18672 A2RRS8 7.19e-28 Centrosomal protein of 78 kDa (Cep78) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium organization [GO:0044782] GO:0005737; GO:0005814; GO:0036064; GO:0044782 1297 FUN_042582 2472 1648 1005 1987 1861 ptg000039l:10063-18672 A2RRS8 7.19e-28 Centrosomal protein of 78 kDa (Cep78) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium organization [GO:0044782] GO:0005737; GO:0005814; GO:0036064; GO:0044782 1298 FUN_042581 101 35 100 123 271 ptg000039l:5358-9464 P48547 6.17e-45 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 1299 FUN_042581 101 35 100 123 271 ptg000039l:5358-9464 P48547 1.67e-32 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Homo sapiens (Human) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030673; GO:0032590; GO:0032809; GO:0035864; GO:0042734; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1903818; GO:1990089 1300 FUN_026199 18771 25326 6847 17956 7973 NA NA NA NA NA NA NA 1301 FUN_042587 166 253 207 289 236 NA NA NA NA NA NA NA 1302 FUN_042586 313 357 109 270 160 ptg000039l:44272-47796 Q7T199 1.04e-42 Potassium voltage-gated channel subfamily A member 10 Gallus gallus (Chicken) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0008076; GO:0016020; GO:0034765; GO:0051260; GO:0071805 1303 FUN_042585 5370 2973 1934 2450 2625 NA NA NA NA NA NA NA 1304 FUN_042584 111 73 120 165 197 NA NA NA NA NA NA NA 1305 FUN_023340 16 55 30 33 21 ptg000017l:6475216-6477550 Q8CGW4 1.08e-22 Transcription factor SOX-30 Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proacrosomal vesicle fusion [GO:0120211]; regulation of transcription by RNA polymerase II [GO:0006357]; response to corticosteroid [GO:0031960]; spermatid development [GO:0007286] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0007286; GO:0008013; GO:0010369; GO:0030178; GO:0031960; GO:0043231; GO:0045944; GO:0120211; GO:1990837 1306 FUN_014660 16887 20885 15456 16744 9042 ptg000009l:1892554-1893319 O60688 7.49e-39 Protein yippee-like 1 Homo sapiens (Human) NA GO:0005634; GO:0046872 1307 FUN_023342 91 49 53 48 109 NA NA NA NA NA NA NA 1308 FUN_040699 16 14 0 0 0 NA NA NA NA NA NA NA 1309 FUN_040698 17 12 0 0 11 NA NA NA NA NA NA NA 1310 FUN_040695 2913 2514 1176 2131 2363 NA NA NA NA NA NA NA 1311 FUN_023344 1161 430 337 430 292 NA NA NA NA NA NA NA 1312 FUN_040697 0 14 0 0 13 NA NA NA NA NA NA NA 1313 FUN_040696 128 55 63 25 14 NA NA NA NA NA NA NA 1314 FUN_040691 66 379 188 43 35 NA NA NA NA NA NA NA 1315 FUN_040690 4142 2031 1554 2009 1571 NA NA NA NA NA NA NA 1316 FUN_040693 1115 1562 953 1179 661 NA NA NA NA NA NA NA 1317 FUN_026193 184 175 202 392 601 NA NA NA NA NA NA NA 1318 FUN_012921 0 2 2 16 0 NA NA NA NA NA NA NA 1319 FUN_012923 29 0 13 74 86 NA NA NA NA NA NA NA 1320 FUN_012924 11 1 4 2 32 NA NA NA NA NA NA NA 1321 FUN_012925 0 4 5 0 16 NA NA NA NA NA NA NA 1322 FUN_012926 99 153 172 345 296 ptg000008l:17259649-17260567 D3ZG27 4.43e-96 UbiA prenyltransferase domain-containing protein 1 (EC 2.5.1.-) (EC 2.5.1.39) Rattus norvegicus (Rat) circulatory system development [GO:0072359]; endothelial cell development [GO:0001885]; menaquinone biosynthetic process [GO:0009234]; ubiquinone biosynthetic process [GO:0006744]; ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate [GO:0032194]; vitamin K biosynthetic process [GO:0042371] GO:0000139; GO:0001885; GO:0002083; GO:0004659; GO:0005634; GO:0005737; GO:0005783; GO:0005789; GO:0006744; GO:0009234; GO:0016020; GO:0016209; GO:0031966; GO:0032194; GO:0042371; GO:0072359 1323 FUN_012927 1166 861 466 714 689 ptg000008l:17276526-17290641 P08510 5.37e-103 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 1324 FUN_014666 521 261 221 345 409 NA NA NA NA NA NA NA 1325 FUN_027826 182 3 5 0 17 NA NA NA NA NA NA NA 1326 FUN_011688 934 857 368 960 549 NA NA NA NA NA NA NA 1327 FUN_041771 8383 6710 2982 5488 3749 NA NA NA NA NA NA NA 1328 FUN_041770 1413 2859 1846 1306 839 NA NA NA NA NA NA NA 1329 FUN_000327 2090 871 1121 1723 879 ntLink_6:1558207-1575121 Q8T5G8 3.74e-23 Chitin synthase (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase) Meloidogyne artiellia (British root-knot nematode) embryo development ending in birth or egg hatching [GO:0009792] GO:0004100; GO:0005886; GO:0009792 1330 FUN_000326 44 0 31 29 81 NA NA NA NA NA NA NA 1331 FUN_000321 720 447 279 862 530 NA NA NA NA NA NA NA 1332 FUN_000320 2625 899 1181 1839 2621 ntLink_6:1474364-1494727 Q9ERH3 1.06e-36 WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG) Rattus norvegicus (Rat) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005737; GO:0008021 1333 FUN_000320 2625 899 1181 1839 2621 ntLink_6:1474364-1494727 Q9ERH3 1.4e-30 WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG) Rattus norvegicus (Rat) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005737; GO:0008021 1334 FUN_000320 2625 899 1181 1839 2621 ntLink_6:1474364-1494727 Q9ERH3 1.89e-21 WD repeat-containing protein 7 (TGF-beta resistance-associated protein TRAG) Rattus norvegicus (Rat) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005737; GO:0008021 1335 FUN_041777 1272 992 684 1181 1456 ptg000035l:7358111-7366869 Q61214 2.16e-50 Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (MP86) (Protein kinase minibrain homolog) (MNBH) Mus musculus (Mouse) amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003713; GO:0003779; GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0005874; GO:0005883; GO:0005884; GO:0006468; GO:0007623; GO:0008092; GO:0008353; GO:0015631; GO:0016607; GO:0018105; GO:0018107; GO:0018108; GO:0030424; GO:0030425; GO:0031115; GO:0033120; GO:0034205; GO:0038083; GO:0042802; GO:0043518; GO:0043621; GO:0045893; GO:0046777; GO:0048025; GO:0048156; GO:0090310; GO:0090312; GO:0106310; GO:0140857; GO:1990904 1336 FUN_041777 1272 992 684 1181 1456 ptg000035l:7358111-7366869 Q61214 1.03e-23 Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (MP86) (Protein kinase minibrain homolog) (MNBH) Mus musculus (Mouse) amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003713; GO:0003779; GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0005874; GO:0005883; GO:0005884; GO:0006468; GO:0007623; GO:0008092; GO:0008353; GO:0015631; GO:0016607; GO:0018105; GO:0018107; GO:0018108; GO:0030424; GO:0030425; GO:0031115; GO:0033120; GO:0034205; GO:0038083; GO:0042802; GO:0043518; GO:0043621; GO:0045893; GO:0046777; GO:0048025; GO:0048156; GO:0090310; GO:0090312; GO:0106310; GO:0140857; GO:1990904 1337 FUN_041777 1272 992 684 1181 1456 ptg000035l:7358111-7366869 Q61214 1.62e-22 Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (MP86) (Protein kinase minibrain homolog) (MNBH) Mus musculus (Mouse) amyloid-beta formation [GO:0034205]; circadian rhythm [GO:0007623]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein deacetylation [GO:0090312]; positive regulation of RNA splicing [GO:0033120]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003713; GO:0003779; GO:0004672; GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005524; GO:0005634; GO:0005737; GO:0005856; GO:0005874; GO:0005883; GO:0005884; GO:0006468; GO:0007623; GO:0008092; GO:0008353; GO:0015631; GO:0016607; GO:0018105; GO:0018107; GO:0018108; GO:0030424; GO:0030425; GO:0031115; GO:0033120; GO:0034205; GO:0038083; GO:0042802; GO:0043518; GO:0043621; GO:0045893; GO:0046777; GO:0048025; GO:0048156; GO:0090310; GO:0090312; GO:0106310; GO:0140857; GO:1990904 1338 FUN_041776 1131 1317 735 1123 2068 ptg000035l:7344462-7347267 Q66KL9 1.24e-29 RNA-binding protein 42 (RNA-binding motif protein 42) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0005634; GO:0005737 1339 FUN_041779 862 487 465 574 1298 NA NA NA NA NA NA NA 1340 FUN_041778 220 409 190 301 489 ptg000035l:7369899-7371809 Q8R123 1.11e-61 FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region] Mus musculus (Mouse) FAD biosynthetic process [GO:0006747] GO:0003919; GO:0005524; GO:0005829; GO:0005886; GO:0006747; GO:0042802 1341 FUN_041778 220 409 190 301 489 ptg000035l:7369899-7371809 Q8R123 3.39e-60 FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region] Mus musculus (Mouse) FAD biosynthetic process [GO:0006747] GO:0003919; GO:0005524; GO:0005829; GO:0005886; GO:0006747; GO:0042802 1342 FUN_000329 1442 1229 988 1084 873 ntLink_6:1590513-1593894 O15182 1.81e-29 Centrin-3 Homo sapiens (Human) cell division [GO:0051301]; centrosome cycle [GO:0007098]; mRNA transport [GO:0051028]; protein transport [GO:0015031] GO:0005509; GO:0005730; GO:0005737; GO:0005813; GO:0005814; GO:0005815; GO:0007098; GO:0008017; GO:0015031; GO:0031683; GO:0032391; GO:0036064; GO:0044615; GO:0051028; GO:0051301; GO:0070390 1343 FUN_000328 738 267 233 266 171 NA NA NA NA NA NA NA 1344 FUN_008668 10426 12412 5385 7802 4467 NA NA NA NA NA NA NA 1345 FUN_008660 9342 8493 5040 8783 6061 ptg000002l:14136576-14138681 Q5R9Y4 5.97e-44 Ras-related protein Rab-7a (EC 3.6.5.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) early endosome to late endosome transport [GO:0045022]; endosome to plasma membrane protein transport [GO:0099638]; lipid catabolic process [GO:0016042]; lipophagy [GO:0061724]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] GO:0000421; GO:0003925; GO:0005525; GO:0005739; GO:0005765; GO:0005770; GO:0005811; GO:0005829; GO:0016042; GO:0030670; GO:0031902; GO:0031966; GO:0033162; GO:0045022; GO:0045335; GO:0061724; GO:0090383; GO:0090385; GO:0099638 1346 FUN_008660 9342 8493 5040 8783 6061 ptg000002l:14136576-14138681 Q5R9Y4 7.43e-26 Ras-related protein Rab-7a (EC 3.6.5.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) early endosome to late endosome transport [GO:0045022]; endosome to plasma membrane protein transport [GO:0099638]; lipid catabolic process [GO:0016042]; lipophagy [GO:0061724]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385] GO:0000421; GO:0003925; GO:0005525; GO:0005739; GO:0005765; GO:0005770; GO:0005811; GO:0005829; GO:0016042; GO:0030670; GO:0031902; GO:0031966; GO:0033162; GO:0045022; GO:0045335; GO:0061724; GO:0090383; GO:0090385; GO:0099638 1347 FUN_008661 4541 1439 1359 3014 1550 ptg000002l:14142621-14150474 Q9SAK4 6.36e-27 Succinate-semialdehyde dehydrogenase, mitochondrial (At-SSADH1) (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member F1) (NAD(+)-dependent succinic semialdehyde dehydrogenase) (Protein ENLARGED FIL EXPRESSING DOMAIN 1) Arabidopsis thaliana (Mouse-ear cress) adaxial/abaxial axis specification [GO:0009943]; cotyledon development [GO:0048825]; gamma-aminobutyric acid catabolic process [GO:0009450]; glutamate decarboxylation to succinate [GO:0006540]; leaf development [GO:0048366]; maintenance of shoot apical meristem identity [GO:0010492]; nitrogen compound metabolic process [GO:0006807]; reactive oxygen species metabolic process [GO:0072593]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; response to salt [GO:1902074] GO:0004777; GO:0005507; GO:0005739; GO:0005759; GO:0005829; GO:0006540; GO:0006807; GO:0009408; GO:0009409; GO:0009416; GO:0009450; GO:0009507; GO:0009570; GO:0009943; GO:0010492; GO:0048366; GO:0048825; GO:0051287; GO:0072593; GO:1902074 1348 FUN_008661 4541 1439 1359 3014 1550 ptg000002l:14142621-14150474 Q9SAK4 4.68e-22 Succinate-semialdehyde dehydrogenase, mitochondrial (At-SSADH1) (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member F1) (NAD(+)-dependent succinic semialdehyde dehydrogenase) (Protein ENLARGED FIL EXPRESSING DOMAIN 1) Arabidopsis thaliana (Mouse-ear cress) adaxial/abaxial axis specification [GO:0009943]; cotyledon development [GO:0048825]; gamma-aminobutyric acid catabolic process [GO:0009450]; glutamate decarboxylation to succinate [GO:0006540]; leaf development [GO:0048366]; maintenance of shoot apical meristem identity [GO:0010492]; nitrogen compound metabolic process [GO:0006807]; reactive oxygen species metabolic process [GO:0072593]; response to cold [GO:0009409]; response to heat [GO:0009408]; response to light stimulus [GO:0009416]; response to salt [GO:1902074] GO:0004777; GO:0005507; GO:0005739; GO:0005759; GO:0005829; GO:0006540; GO:0006807; GO:0009408; GO:0009409; GO:0009416; GO:0009450; GO:0009507; GO:0009570; GO:0009943; GO:0010492; GO:0048366; GO:0048825; GO:0051287; GO:0072593; GO:1902074 1349 FUN_008662 2233 446 734 626 403 NA NA NA NA NA NA NA 1350 FUN_008663 166 184 190 272 208 ptg000002l:14167465-14168890 P13439 1.51e-180 Uridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; cellular response to xenobiotic stimulus [GO:0071466]; female pregnancy [GO:0007565]; lactation [GO:0007595]; pyrimidine nucleobase biosynthetic process [GO:0019856]; UDP biosynthetic process [GO:0006225]; UMP biosynthetic process [GO:0006222] GO:0004588; GO:0004590; GO:0005634; GO:0005737; GO:0006207; GO:0006222; GO:0006225; GO:0007565; GO:0007595; GO:0019856; GO:0042802; GO:0044205; GO:0071466 1351 FUN_008664 685 525 297 325 233 NA NA NA NA NA NA NA 1352 FUN_008665 1913 1261 784 1551 1137 ptg000002l:14184728-14198118 Q4L1J4 4.59e-28 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) Rattus norvegicus (Rat) positive regulation of cell-cell adhesion [GO:0022409]; signal transduction [GO:0007165] GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0005911; GO:0005912; GO:0005923; GO:0007165; GO:0016020; GO:0022409; GO:0042995; GO:0051393; GO:0071944 1353 FUN_008665 1913 1261 784 1551 1137 ptg000002l:14184728-14198118 Q4L1J4 1.92e-22 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane-associated guanylate kinase inverted 1) (MAGI-1) Rattus norvegicus (Rat) positive regulation of cell-cell adhesion [GO:0022409]; signal transduction [GO:0007165] GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0005911; GO:0005912; GO:0005923; GO:0007165; GO:0016020; GO:0022409; GO:0042995; GO:0051393; GO:0071944 1354 FUN_008666 146 59 68 107 83 NA NA NA NA NA NA NA 1355 FUN_008667 1386 545 541 787 861 ptg000002l:14202612-14206455 Q8TD16 3.1e-105 Protein bicaudal D homolog 2 (Bic-D 2) Homo sapiens (Human) centrosome localization [GO:0051642]; microtubule anchoring at microtubule organizing center [GO:0072393]; microtubule-based movement [GO:0007018]; minus-end-directed organelle transport along microtubule [GO:0072385]; mRNA transport [GO:0051028]; protein localization to Golgi apparatus [GO:0034067]; protein localization to organelle [GO:0033365]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0005635; GO:0005642; GO:0005643; GO:0005737; GO:0005794; GO:0005813; GO:0005829; GO:0005886; GO:0006890; GO:0007018; GO:0008093; GO:0015031; GO:0031267; GO:0031410; GO:0033365; GO:0034067; GO:0034452; GO:0051028; GO:0051642; GO:0051959; GO:0070507; GO:0070840; GO:0072385; GO:0072393 1356 FUN_029038 280 199 234 327 238 ptg000022l:7525415-7534384 Q63881 3.82e-70 Potassium voltage-gated channel subfamily D member 2 (RK5) (Shal1) (Voltage-gated potassium channel subunit Kv4.2) Rattus norvegicus (Rat) action potential [GO:0001508]; cardiac muscle cell action potential [GO:0086001]; cellular response to hypoxia [GO:0071456]; cellular response to mechanical stimulus [GO:0071260]; cellular response to xenobiotic stimulus [GO:0071466]; locomotor rhythm [GO:0045475]; neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0001508; GO:0005216; GO:0005249; GO:0005250; GO:0005267; GO:0005886; GO:0005901; GO:0006813; GO:0008076; GO:0014069; GO:0016020; GO:0019228; GO:0019233; GO:0030315; GO:0030425; GO:0032809; GO:0034705; GO:0034765; GO:0042383; GO:0043005; GO:0043025; GO:0043197; GO:0043204; GO:0044853; GO:0044877; GO:0045211; GO:0045475; GO:0046872; GO:0051260; GO:0070161; GO:0071260; GO:0071456; GO:0071466; GO:0071805; GO:0086001; GO:0097038; GO:0098978; GO:0098982; GO:0099634; GO:1905030 1357 FUN_029039 0 0 44 0 4 NA NA NA NA NA NA NA 1358 FUN_026702 4 0 0 15 4 NA NA NA NA NA NA NA 1359 FUN_029030 94 30 84 62 181 NA NA NA NA NA NA NA 1360 FUN_029031 14 31 113 219 110 NA NA NA NA NA NA NA 1361 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 5.52e-40 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1362 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 5.51e-36 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1363 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 1.06e-32 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1364 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 2.13e-30 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1365 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 4.65e-26 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1366 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 4.65e-26 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1367 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 8.94e-26 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1368 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 1.43e-25 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1369 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 1.52e-23 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1370 FUN_029032 3541 2234 2452 3506 3235 ptg000022l:7429412-7493210 Q9C0G6 4.1e-22 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 1371 FUN_029033 21 7 18 109 0 NA NA NA NA NA NA NA 1372 FUN_029034 0 0 0 26 8 NA NA NA NA NA NA NA 1373 FUN_029035 21 0 8 44 8 NA NA NA NA NA NA NA 1374 FUN_029036 0 22 0 0 0 NA NA NA NA NA NA NA 1375 FUN_029037 207 131 107 198 146 NA NA NA NA NA NA NA 1376 FUN_033006 14 159 302 185 51 NA NA NA NA NA NA NA 1377 FUN_033007 84 262 220 223 65 NA NA NA NA NA NA NA 1378 FUN_033004 703 43 0 4 0 NA NA NA NA NA NA NA 1379 FUN_033005 32 45 58 30 48 NA NA NA NA NA NA NA 1380 FUN_033003 43 0 0 0 0 NA NA NA NA NA NA NA 1381 FUN_033000 282 113 143 474 173 NA NA NA NA NA NA NA 1382 FUN_033008 118 192 286 251 246 NA NA NA NA NA NA NA 1383 FUN_033009 61 26 23 16 89 NA NA NA NA NA NA NA 1384 FUN_016713 78 32 35 199 151 NA NA NA NA NA NA NA 1385 FUN_016712 873 1131 601 832 541 NA NA NA NA NA NA NA 1386 FUN_016710 1605 871 632 1828 1258 NA NA NA NA NA NA NA 1387 FUN_042877 122 385 119 247 212 NA NA NA NA NA NA NA 1388 FUN_042876 2185 1186 1316 1693 1724 NA NA NA NA NA NA NA 1389 FUN_042875 1952 1154 583 1332 1146 NA NA NA NA NA NA NA 1390 FUN_044092 101 188 181 182 517 NA NA NA NA NA NA NA 1391 FUN_042879 0 0 2 0 14 NA NA NA NA NA NA NA 1392 FUN_003675 0 0 0 12 0 NA NA NA NA NA NA NA 1393 FUN_044097 47 87 102 134 325 NA NA NA NA NA NA NA 1394 FUN_019524 0 0 0 0 16 NA NA NA NA NA NA NA 1395 FUN_044095 9 7 31 7 193 NA NA NA NA NA NA NA 1396 FUN_018311 110 0 8 0 0 NA NA NA NA NA NA NA 1397 FUN_044094 16 0 9 0 23 NA NA NA NA NA NA NA 1398 FUN_010658 0 0 12 22 0 NA NA NA NA NA NA NA 1399 FUN_028348 2869 1946 758 2337 1731 NA NA NA NA NA NA NA 1400 FUN_010651 554 82 54 229 69 NA NA NA NA NA NA NA 1401 FUN_010652 37 24 0 17 99 NA NA NA NA NA NA NA 1402 FUN_028342 17 5 14 37 47 NA NA NA NA NA NA NA 1403 FUN_010654 277 131 172 172 266 NA NA NA NA NA NA NA 1404 FUN_010656 893 221 97 150 862 ptg000007l:1231648-1243840 Q8QHA5 6.06e-32 DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)] Xenopus laevis (African clawed frog) base-excision repair [GO:0006284]; DNA double-strand break processing [GO:0000729]; DNA replication [GO:0006260]; DNA replication checkpoint signaling [GO:0000076]; DNA replication, Okazaki fragment processing [GO:0033567]; DNA replication, removal of RNA primer [GO:0043137]; double-strand break repair via single-strand annealing [GO:0045002]; mitochondrial DNA replication [GO:0006264]; positive regulation of DNA replication [GO:0045740] GO:0000076; GO:0000729; GO:0003677; GO:0003678; GO:0004518; GO:0005524; GO:0005634; GO:0005739; GO:0006260; GO:0006264; GO:0006284; GO:0016887; GO:0016890; GO:0017108; GO:0017116; GO:0033567; GO:0043137; GO:0043139; GO:0045002; GO:0045740; GO:0046872; GO:0051539 1405 FUN_010657 9 10 0 18 0 NA NA NA NA NA NA NA 1406 FUN_041307 0 0 33 1 2 NA NA NA NA NA NA NA 1407 FUN_041300 0 0 0 0 12 NA NA NA NA NA NA NA 1408 FUN_041301 0 0 0 0 13 NA NA NA NA NA NA NA 1409 FUN_041309 1 12 4 6 4 NA NA NA NA NA NA NA 1410 FUN_007702 0 14 11 20 0 NA NA NA NA NA NA NA 1411 FUN_007300 0 3 0 0 19 NA NA NA NA NA NA NA 1412 FUN_002951 3 0 7 0 0 NA NA NA NA NA NA NA 1413 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 6.28e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1414 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 1.78e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1415 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 1.54e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1416 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 9.47e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1417 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 7.05e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1418 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 4.6e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1419 FUN_018310 186 24 114 145 98 ptg000012l:7506167-7510713 Q96AY4 1.08e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1420 FUN_007706 114 0 0 0 169 NA NA NA NA NA NA NA 1421 FUN_007301 0 37 0 0 0 NA NA NA NA NA NA NA 1422 FUN_007704 0 0 48 61 39 ptg000002l:3429690-3438541 P97363 1.13e-28 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 1423 FUN_007704 0 0 48 61 39 ptg000002l:3429690-3438541 P97363 1.13e-28 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 1424 FUN_007704 0 0 48 61 39 ptg000002l:3429690-3438541 P97363 1.26e-22 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 1425 FUN_043040 4246 3482 1625 3005 2234 NA NA NA NA NA NA NA 1426 FUN_043044 53 15 3 68 49 ptg000047l:3364988-3371231 Q96AY4 4.23e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1427 FUN_043044 53 15 3 68 49 ptg000047l:3364988-3371231 Q96AY4 1.28e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1428 FUN_043044 53 15 3 68 49 ptg000047l:3364988-3371231 Q96AY4 1.39e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1429 FUN_043044 53 15 3 68 49 ptg000047l:3364988-3371231 Q96AY4 4.39e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1430 FUN_043044 53 15 3 68 49 ptg000047l:3364988-3371231 Q96AY4 6.12e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1431 FUN_043044 53 15 3 68 49 ptg000047l:3364988-3371231 Q96AY4 3.29e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1432 FUN_043047 0 0 0 0 35 NA NA NA NA NA NA NA 1433 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 6.72e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1434 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 1.34e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1435 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 2.9e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1436 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 8.63e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1437 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 1.47e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1438 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 2.08e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1439 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 3.36e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1440 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 2.2e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1441 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 1.23e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1442 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 2.39e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1443 FUN_043046 39 12 18 39 19 ptg000047l:3389524-3395928 Q96AY4 1.29e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1444 FUN_013673 0 0 8 0 3 NA NA NA NA NA NA NA 1445 FUN_011723 2246 1798 953 1701 1325 ptg000008l:600718-615391 Q8CD19 3.5e-33 LanC-like protein 3 Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; peptide modification [GO:0031179] GO:0005886; GO:0005975; GO:0031179 1446 FUN_013677 0 0 13 0 20 NA NA NA NA NA NA NA 1447 FUN_013679 0 59 41 0 292 NA NA NA NA NA NA NA 1448 FUN_002435 101395 104805 46428 95723 58874 ntLink_8:1556142-1558468 P69005 9.51e-180 Actin, cytoskeletal 2B (EC 3.6.4.-) (Actin, cytoskeletal IIB) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 1449 FUN_002435 101395 104805 46428 95723 58874 ntLink_8:1556142-1558468 P69005 8.72e-56 Actin, cytoskeletal 2B (EC 3.6.4.-) (Actin, cytoskeletal IIB) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 1450 FUN_002435 101395 104805 46428 95723 58874 ntLink_8:1556142-1558468 P69005 8.72e-56 Actin, cytoskeletal 2B (EC 3.6.4.-) (Actin, cytoskeletal IIB) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 1451 FUN_037437 65 21 0 43 38 NA NA NA NA NA NA NA 1452 FUN_011720 447 254 171 285 72 NA NA NA NA NA NA NA 1453 FUN_011727 316 255 189 168 329 ptg000008l:637826-641460 Q8VEJ1 2.06e-55 GPN-loop GTPase 2 (ATP-binding domain 1 family member B) Mus musculus (Mouse) NA GO:0003924; GO:0005525 1454 FUN_002432 1987 1281 1119 1826 1307 ntLink_8:1515747-1536955 Q7LHG5 4.44e-79 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 1455 FUN_002431 32 66 79 106 95 NA NA NA NA NA NA NA 1456 FUN_023698 2243 2272 1448 1636 1101 ptg000017l:10731401-10733758 Q01890 2.83e-35 Ras-like GTP-binding protein YPT1 Phytophthora infestans (Potato late blight agent) (Botrytis infestans) autophagy [GO:0006914]; protein transport [GO:0015031] GO:0000139; GO:0003924; GO:0005525; GO:0005789; GO:0006914; GO:0015031; GO:0034045 1457 FUN_023698 2243 2272 1448 1636 1101 ptg000017l:10731401-10733758 Q01890 5.48e-23 Ras-like GTP-binding protein YPT1 Phytophthora infestans (Potato late blight agent) (Botrytis infestans) autophagy [GO:0006914]; protein transport [GO:0015031] GO:0000139; GO:0003924; GO:0005525; GO:0005789; GO:0006914; GO:0015031; GO:0034045 1458 FUN_023699 3608 1240 2066 2642 2684 NA NA NA NA NA NA NA 1459 FUN_023692 1099 1323 514 1024 739 NA NA NA NA NA NA NA 1460 FUN_023693 64 0 78 84 48 ptg000017l:10692340-10694777 Q7Z402 2.55e-40 Transmembrane channel-like protein 7 Homo sapiens (Human) NA GO:0005886; GO:0008381 1461 FUN_023693 64 0 78 84 48 ptg000017l:10692340-10694777 Q7Z402 2.98e-37 Transmembrane channel-like protein 7 Homo sapiens (Human) NA GO:0005886; GO:0008381 1462 FUN_023691 299 480 233 311 269 NA NA NA NA NA NA NA 1463 FUN_023696 119 10 26 28 0 NA NA NA NA NA NA NA 1464 FUN_023697 1430 889 541 1769 790 ptg000017l:10728905-10731001 B3EWZ2 5.17e-133 Uncharacterized skeletal organic matrix protein 8 (Uncharacterized SOMP-8) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 1465 FUN_023694 7722 7125 4262 6506 4087 ptg000017l:10696951-10704685 Q9BTU6 1.56e-29 Phosphatidylinositol 4-kinase type 2-alpha (EC 2.7.1.67) (Phosphatidylinositol 4-kinase type II-alpha) Homo sapiens (Human) endosome organization [GO:0007032]; Golgi organization [GO:0007030]; phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphorylation [GO:0016310] GO:0000139; GO:0000287; GO:0004430; GO:0005524; GO:0005739; GO:0005765; GO:0005768; GO:0005802; GO:0005829; GO:0005886; GO:0006661; GO:0007030; GO:0007032; GO:0016020; GO:0016310; GO:0030425; GO:0031410; GO:0031901; GO:0035651; GO:0035838; GO:0042734; GO:0043005; GO:0043025; GO:0043204; GO:0045121; GO:0046854 1466 FUN_023695 23 99 182 53 124 NA NA NA NA NA NA NA 1467 FUN_025939 80409 64525 44999 81538 80902 ptg000020l:2233966-2237669 Q2HJ86 5.18e-166 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 1468 FUN_025939 80409 64525 44999 81538 80902 ptg000020l:2233966-2237669 Q2HJ86 5.18e-166 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 1469 FUN_025939 80409 64525 44999 81538 80902 ptg000020l:2233966-2237669 Q2HJ86 5.18e-166 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 1470 FUN_025939 80409 64525 44999 81538 80902 ptg000020l:2233966-2237669 Q2HJ86 9.37e-41 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 1471 FUN_025939 80409 64525 44999 81538 80902 ptg000020l:2233966-2237669 Q2HJ86 5.54e-23 Tubulin alpha-1D chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha-1D chain] Bos taurus (Bovine) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0016787; GO:0046872 1472 FUN_025938 330 1549 1770 10999 237 ptg000020l:2213960-2221154 Q8T6A5 2.17e-166 Tubulin alpha-1 chain (EC 3.6.5.-) Aplysia californica (California sea hare) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 1473 FUN_025938 330 1549 1770 10999 237 ptg000020l:2213960-2221154 Q8T6A5 2.17e-166 Tubulin alpha-1 chain (EC 3.6.5.-) Aplysia californica (California sea hare) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 1474 FUN_025938 330 1549 1770 10999 237 ptg000020l:2213960-2221154 Q8T6A5 1.86e-42 Tubulin alpha-1 chain (EC 3.6.5.-) Aplysia californica (California sea hare) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 1475 FUN_025938 330 1549 1770 10999 237 ptg000020l:2213960-2221154 Q8T6A5 1.89e-21 Tubulin alpha-1 chain (EC 3.6.5.-) Aplysia californica (California sea hare) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 1476 FUN_025935 4396 2220 1723 2314 2257 NA NA NA NA NA NA NA 1477 FUN_025934 79 18 42 8 25 NA NA NA NA NA NA NA 1478 FUN_025937 134 85 31 60 69 NA NA NA NA NA NA NA 1479 FUN_025931 237 256 44 241 198 ptg000020l:2141269-2148896 Q96DM1 1.06e-41 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 1480 FUN_025931 237 256 44 241 198 ptg000020l:2141269-2148896 Q96DM1 1.06e-41 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 1481 FUN_025930 5 12 4 39 24 NA NA NA NA NA NA NA 1482 FUN_025933 742 210 171 646 644 NA NA NA NA NA NA NA 1483 FUN_025932 873 507 233 350 542 ptg000020l:2150388-2158515 Q6NUT3 2.13e-31 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 1484 FUN_037438 21 12 34 20 0 NA NA NA NA NA NA NA 1485 FUN_023528 0 0 42 0 0 NA NA NA NA NA NA NA 1486 FUN_023529 845 333 1065 628 1124 NA NA NA NA NA NA NA 1487 FUN_026629 1037 872 827 1004 891 NA NA NA NA NA NA NA 1488 FUN_023524 291 136 164 341 279 NA NA NA NA NA NA NA 1489 FUN_023525 16 3 43 28 28 NA NA NA NA NA NA NA 1490 FUN_041479 382 181 174 375 316 NA NA NA NA NA NA NA 1491 FUN_023520 24 0 0 0 95 NA NA NA NA NA NA NA 1492 FUN_023521 43 69 40 82 138 ptg000017l:8536637-8538353 Q91175 6.87e-48 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 1493 FUN_023522 1028 1006 700 1720 1394 NA NA NA NA NA NA NA 1494 FUN_023523 1376 1352 992 1439 1267 NA NA NA NA NA NA NA 1495 FUN_041477 794 312 267 536 387 NA NA NA NA NA NA NA 1496 FUN_013954 0 0 0 0 77 NA NA NA NA NA NA NA 1497 FUN_015536 6 0 0 0 0 NA NA NA NA NA NA NA 1498 FUN_013955 39 0 12 0 22 NA NA NA NA NA NA NA 1499 FUN_040026 19 32 14 9 45 NA NA NA NA NA NA NA 1500 FUN_041472 203 93 0 181 158 NA NA NA NA NA NA NA 1501 FUN_015538 0 0 0 0 6 NA NA NA NA NA NA NA 1502 FUN_026737 72 18 40 18 94 NA NA NA NA NA NA NA 1503 FUN_029978 0 13 0 0 0 NA NA NA NA NA NA NA 1504 FUN_041470 200 120 74 185 143 NA NA NA NA NA NA NA 1505 FUN_019311 1174 1174 1063 760 378 NA NA NA NA NA NA NA 1506 FUN_030633 175 38 182 45 540 NA NA NA NA NA NA NA 1507 FUN_018669 19 0 0 0 0 ptg000012l:11756958-11758486 P11369 7.36e-29 LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Mus musculus (Mouse) DNA recombination [GO:0006310] GO:0003964; GO:0004519; GO:0006310; GO:0046872 1508 FUN_018668 18 2 0 4 0 NA NA NA NA NA NA NA 1509 FUN_018665 184 35 32 65 352 NA NA NA NA NA NA NA 1510 FUN_018660 198 272 220 88 92 NA NA NA NA NA NA NA 1511 FUN_018663 0 0 0 0 49 NA NA NA NA NA NA NA 1512 FUN_025203 2 0 0 0 28 NA NA NA NA NA NA NA 1513 FUN_025202 0 0 0 0 47 NA NA NA NA NA NA NA 1514 FUN_025209 7 0 7 4 30 NA NA NA NA NA NA NA 1515 FUN_039834 3 0 0 0 6 NA NA NA NA NA NA NA 1516 FUN_042917 1511 710 734 491 855 ptg000047l:1741243-1745917 P39428 1.53e-66 TNF receptor-associated factor 1 Mus musculus (Mouse) apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005737; GO:0006915; GO:0008270; GO:0009898; GO:0031625; GO:0031996; GO:0033209; GO:0042802; GO:0043122; GO:0046330; GO:0051092; GO:0070534; GO:2001236 1517 FUN_025306 143 33 17 78 0 NA NA NA NA NA NA NA 1518 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 2.73e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1519 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 1.75e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1520 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 3.07e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1521 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 5.82e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1522 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 9.51e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1523 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 2.35e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1524 FUN_009177 113 126 34 73 50 ptg000004l:3570216-3580169 Q96AY4 7.63e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1525 FUN_039833 188 16 56 33 117 NA NA NA NA NA NA NA 1526 FUN_022711 2108 2139 1432 2032 1266 NA NA NA NA NA NA NA 1527 FUN_025428 4619 1556 1664 2090 1074 NA NA NA NA NA NA NA 1528 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 4.43e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1529 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 2.46e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1530 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 7.57e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1531 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 1.49e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1532 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 1.15e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1533 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 1.2e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1534 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 7.85e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1535 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 2.27e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1536 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 3.46e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1537 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 1.03e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1538 FUN_009175 82 153 50 54 31 ptg000004l:3539497-3542140 Q96AY4 4.01e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1539 FUN_022713 90 39 14 87 148 NA NA NA NA NA NA NA 1540 FUN_025426 167 170 81 207 298 ptg000019l:2471233-2473730 Q3U4G3 1.7e-66 Xyloside xylosyltransferase 1 (EC 2.4.2.62) (UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase) Mus musculus (Mouse) O-glycan processing [GO:0016266] GO:0000287; GO:0005789; GO:0016266; GO:0030145; GO:0035252; GO:0140560 1541 FUN_022714 34 132 71 91 182 NA NA NA NA NA NA NA 1542 FUN_035874 11 13 17 3 49 NA NA NA NA NA NA NA 1543 FUN_025425 4188 4664 693 3370 1179 NA NA NA NA NA NA NA 1544 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 1.77e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1545 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 1.12e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1546 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 1.12e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1547 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 3.99e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1548 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 5.99e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1549 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 8.47e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1550 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 2.51e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1551 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 1.23e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1552 FUN_009172 9 0 0 38 0 ptg000004l:3515804-3521312 Q96AY4 1.62e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1553 FUN_025424 24 23 31 13 48 NA NA NA NA NA NA NA 1554 FUN_022716 3823 2339 1904 2639 2807 NA NA NA NA NA NA NA 1555 FUN_019314 9 0 11 2 59 NA NA NA NA NA NA NA 1556 FUN_025423 4 0 4 9 70 NA NA NA NA NA NA NA 1557 FUN_022434 368 205 225 404 413 NA NA NA NA NA NA NA 1558 FUN_019532 0 0 64 113 110 NA NA NA NA NA NA NA 1559 FUN_019533 0 0 0 31 34 NA NA NA NA NA NA NA 1560 FUN_019530 0 0 0 0 10 NA NA NA NA NA NA NA 1561 FUN_019531 0 0 3 13 16 NA NA NA NA NA NA NA 1562 FUN_019535 0 0 6 0 26 NA NA NA NA NA NA NA 1563 FUN_022436 4168 4106 2970 3173 1836 NA NA NA NA NA NA NA 1564 FUN_004753 0 18 17 9 11 NA NA NA NA NA NA NA 1565 FUN_035876 411 278 176 136 321 ptg000025l:12803374-12806314 Q9EQY6 2.03e-28 GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M) Rattus norvegicus (Rat) GPI anchor biosynthetic process [GO:0006506] GO:0000030; GO:0004376; GO:0005789; GO:0006506; GO:0051751; GO:1990529 1566 FUN_013921 20 0 0 33 0 NA NA NA NA NA NA NA 1567 FUN_035236 362 299 176 304 580 NA NA NA NA NA NA NA 1568 FUN_030602 0 0 0 0 17 NA NA NA NA NA NA NA 1569 FUN_035231 751 1081 347 1408 2604 NA NA NA NA NA NA NA 1570 FUN_013920 0 0 0 15 11 NA NA NA NA NA NA NA 1571 FUN_035239 184 109 120 84 345 ptg000025l:5505274-5509486 P54278 2.81e-111 Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006298; GO:0009410; GO:0016446; GO:0016887; GO:0032138; GO:0032300; GO:0032389; GO:0036464; GO:0140664 1572 FUN_035239 184 109 120 84 345 ptg000025l:5505274-5509486 P54278 3.47e-41 Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006298; GO:0009410; GO:0016446; GO:0016887; GO:0032138; GO:0032300; GO:0032389; GO:0036464; GO:0140664 1573 FUN_035239 184 109 120 84 345 ptg000025l:5505274-5509486 P54278 3.99e-33 Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006298; GO:0009410; GO:0016446; GO:0016887; GO:0032138; GO:0032300; GO:0032389; GO:0036464; GO:0140664 1574 FUN_035239 184 109 120 84 345 ptg000025l:5505274-5509486 P54278 4.58e-28 Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0004519; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006298; GO:0009410; GO:0016446; GO:0016887; GO:0032138; GO:0032300; GO:0032389; GO:0036464; GO:0140664 1575 FUN_036764 1183 253 374 1099 1358 NA NA NA NA NA NA NA 1576 FUN_036767 323 433 187 236 201 ptg000026l:1684061-1688955 P57681 3.91e-41 Farnesylcysteine lyase (EC 1.8.3.6) Arabidopsis thaliana (Mouse-ear cress) abscisic acid-activated signaling pathway [GO:0009738]; farnesyl diphosphate metabolic process [GO:0045338]; prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328] GO:0000325; GO:0001735; GO:0005764; GO:0009738; GO:0030327; GO:0030328; GO:0045338; GO:0102149 1577 FUN_036767 323 433 187 236 201 ptg000026l:1684061-1688955 P57681 3.91e-41 Farnesylcysteine lyase (EC 1.8.3.6) Arabidopsis thaliana (Mouse-ear cress) abscisic acid-activated signaling pathway [GO:0009738]; farnesyl diphosphate metabolic process [GO:0045338]; prenylated protein catabolic process [GO:0030327]; prenylcysteine catabolic process [GO:0030328] GO:0000325; GO:0001735; GO:0005764; GO:0009738; GO:0030327; GO:0030328; GO:0045338; GO:0102149 1578 FUN_036760 10 2 17 0 10 NA NA NA NA NA NA NA 1579 FUN_036762 0 0 6 0 0 NA NA NA NA NA NA NA 1580 FUN_036763 7 15 8 20 7 NA NA NA NA NA NA NA 1581 FUN_036768 42 120 67 85 50 NA NA NA NA NA NA NA 1582 FUN_007206 0 0 0 9 3 NA NA NA NA NA NA NA 1583 FUN_039727 0 0 11 0 0 NA NA NA NA NA NA NA 1584 FUN_007204 0 271 0 0 0 NA NA NA NA NA NA NA 1585 FUN_007202 5 9 10 0 89 NA NA NA NA NA NA NA 1586 FUN_039723 0 7 0 1 0 NA NA NA NA NA NA NA 1587 FUN_013927 0 0 0 0 9 NA NA NA NA NA NA NA 1588 FUN_039728 0 4 23 0 0 ptg000030l:2993670-2998503 Q27409 3.49e-27 Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1) Mytilus galloprovincialis (Mediterranean mussel) NA GO:0005576 1589 FUN_039728 0 4 23 0 0 ptg000030l:2993670-2998503 Q27409 3.71e-27 Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1) Mytilus galloprovincialis (Mediterranean mussel) NA GO:0005576 1590 FUN_039728 0 4 23 0 0 ptg000030l:2993670-2998503 Q27409 7.43e-26 Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1) Mytilus galloprovincialis (Mediterranean mussel) NA GO:0005576 1591 FUN_039728 0 4 23 0 0 ptg000030l:2993670-2998503 Q27409 2.16e-24 Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1) Mytilus galloprovincialis (Mediterranean mussel) NA GO:0005576 1592 FUN_039728 0 4 23 0 0 ptg000030l:2993670-2998503 Q27409 1.14e-22 Adhesive plaque matrix protein (Foot protein 1) (MGFP-1) (MGFP1) Mytilus galloprovincialis (Mediterranean mussel) NA GO:0005576 1593 FUN_013925 0 16 17 0 9 NA NA NA NA NA NA NA 1594 FUN_019338 102 115 761 204 282 NA NA NA NA NA NA NA 1595 FUN_008321 674 146 267 516 380 ptg000002l:10256548-10269898 B8V7S0 1.2e-118 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1596 FUN_008321 674 146 267 516 380 ptg000002l:10256548-10269898 B8V7S0 2.84e-114 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1597 FUN_008321 674 146 267 516 380 ptg000002l:10256548-10269898 B8V7S0 5.92e-31 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1598 FUN_008321 674 146 267 516 380 ptg000002l:10256548-10269898 B8V7S0 7.47e-30 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1599 FUN_008321 674 146 267 516 380 ptg000002l:10256548-10269898 B8V7S0 8.8e-28 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1600 FUN_008321 674 146 267 516 380 ptg000002l:10256548-10269898 B8V7S0 1.33e-26 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1601 FUN_024542 0 57 31 44 66 NA NA NA NA NA NA NA 1602 FUN_013924 1 3 2 0 52 NA NA NA NA NA NA NA 1603 FUN_037495 4627 2556 2581 4421 2704 ptg000026l:11103991-11120899 Q60431 1.49e-28 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 1604 FUN_037495 4627 2556 2581 4421 2704 ptg000026l:11103991-11120899 Q60431 4.01e-25 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 1605 FUN_037495 4627 2556 2581 4421 2704 ptg000026l:11103991-11120899 Q60431 9.43e-25 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 1606 FUN_037494 3604 489 2277 4580 3601 ptg000026l:11082826-11102980 Q60431 3.61e-27 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 1607 FUN_037494 3604 489 2277 4580 3601 ptg000026l:11082826-11102980 Q60431 7.88e-21 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 1608 FUN_037497 11 0 0 0 44 NA NA NA NA NA NA NA 1609 FUN_037496 7697 5136 3842 5915 4753 ptg000026l:11127631-11141024 Q78EA7 1.87e-95 Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Bone morphogenetic protein 4 receptor) (CD antigen CD292) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; atrioventricular node cell development [GO:0060928]; atrioventricular valve development [GO:0003171]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; cardiac conduction system development [GO:0003161]; cardiac right ventricle morphogenesis [GO:0003215]; cartilage development [GO:0051216]; cell differentiation [GO:0030154]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; central nervous system neuron differentiation [GO:0021953]; chondrocyte differentiation [GO:0002062]; developmental growth [GO:0048589]; dorsal aorta morphogenesis [GO:0035912]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; ectoderm development [GO:0007398]; embryonic digit morphogenesis [GO:0042733]; embryonic morphogenesis [GO:0048598]; embryonic organ development [GO:0048568]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; endoderm development [GO:0007492]; epithelial cell proliferation [GO:0050673]; fibrous ring of heart morphogenesis [GO:1905285]; heart development [GO:0007507]; heart formation [GO:0060914]; heart morphogenesis [GO:0003007]; hindlimb morphogenesis [GO:0035137]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; lateral mesoderm development [GO:0048368]; lung development [GO:0030324]; mesendoderm development [GO:0048382]; mesoderm formation [GO:0001707]; mitral valve morphogenesis [GO:0003183]; Mullerian duct regression [GO:0001880]; negative regulation of gene expression [GO:0010629]; negative regulation of muscle cell differentiation [GO:0051148]; negative regulation of neurogenesis [GO:0050768]; negative regulation of smooth muscle cell migration [GO:0014912]; nervous system development [GO:0007399]; neural crest cell development [GO:0014032]; neural plate mediolateral regionalization [GO:0021998]; neural plate pattern specification [GO:0060896]; odontogenesis of dentin-containing tooth [GO:0042475]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; paraxial mesoderm development [GO:0048339]; paraxial mesoderm structural organization [GO:0048352]; pattern specification process [GO:0007389]; pharyngeal arch artery morphogenesis [GO:0061626]; pituitary gland development [GO:0021983]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cardiac ventricle development [GO:1904414]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta2 production [GO:0032915]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cellular senescence [GO:2000772]; regulation of lateral mesodermal cell fate specification [GO:0048378]; roof of mouth development [GO:0060021]; somatic stem cell population maintenance [GO:0035019]; somitogenesis [GO:0001756]; stem cell population maintenance [GO:0019827]; tricuspid valve morphogenesis [GO:0003186]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001525; GO:0001649; GO:0001701; GO:0001707; GO:0001756; GO:0001880; GO:0002053; GO:0002062; GO:0003007; GO:0003148; GO:0003151; GO:0003161; GO:0003171; GO:0003183; GO:0003186; GO:0003203; GO:0003215; GO:0003222; GO:0003223; GO:0003272; GO:0004674; GO:0005025; GO:0005524; GO:0005886; GO:0005901; GO:0006468; GO:0006955; GO:0007389; GO:0007398; GO:0007399; GO:0007492; GO:0007507; GO:0009897; GO:0009950; GO:0009952; GO:0009953; GO:0009986; GO:0010628; GO:0010629; GO:0010862; GO:0014032; GO:0014912; GO:0019211; GO:0019827; GO:0021953; GO:0021983; GO:0021998; GO:0030154; GO:0030324; GO:0030425; GO:0030501; GO:0030509; GO:0032915; GO:0035019; GO:0035137; GO:0035912; GO:0036122; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043235; GO:0043539; GO:0045669; GO:0045944; GO:0046332; GO:0046872; GO:0048339; GO:0048352; GO:0048368; GO:0048378; GO:0048382; GO:0048568; GO:0048589; GO:0048598; GO:0050673; GO:0050679; GO:0050768; GO:0051148; GO:0051216; GO:0060021; GO:0060043; GO:0060045; GO:0060391; GO:0060412; GO:0060896; GO:0060914; GO:0060928; GO:0061312; GO:0061626; GO:0071363; GO:0071773; GO:0098821; GO:0140537; GO:1902895; GO:1904414; GO:1904707; GO:1905285; GO:2000772 1610 FUN_037491 12986 19178 16258 22528 14062 ptg000026l:11052000-11057763 Q5R5H1 3.12e-58 S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to leukemia inhibitory factor [GO:1990830]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0004478; GO:0005524; GO:0006556; GO:0006730; GO:0034214; GO:0042802; GO:0046872; GO:0048269; GO:0051291; GO:1990830 1611 FUN_037491 12986 19178 16258 22528 14062 ptg000026l:11052000-11057763 Q5R5H1 1.11e-25 S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to leukemia inhibitory factor [GO:1990830]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0004478; GO:0005524; GO:0006556; GO:0006730; GO:0034214; GO:0042802; GO:0046872; GO:0048269; GO:0051291; GO:1990830 1612 FUN_037490 446 349 225 476 367 ptg000026l:11043069-11049360 Q6P616 2.79e-23 Pre-mRNA-splicing factor RBM22 (RNA-binding motif protein 22) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of RNA splicing [GO:0033120] GO:0005634; GO:0005681; GO:0005737; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0046872 1613 FUN_037493 8167 9446 5300 10351 8609 NA NA NA NA NA NA NA 1614 FUN_037492 2890 2721 1383 2327 1511 ptg000026l:11062485-11066895 Q8BPB0 9.2e-37 MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A) Mus musculus (Mouse) hippo signaling [GO:0035329]; positive regulation of protein phosphorylation [GO:0001934]; regulation of protein autophosphorylation [GO:0031952]; signal transduction [GO:0007165] GO:0001934; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007165; GO:0019209; GO:0019900; GO:0030295; GO:0031952; GO:0035329; GO:0046872 1615 FUN_037492 2890 2721 1383 2327 1511 ptg000026l:11062485-11066895 Q8BPB0 2.71e-24 MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A) Mus musculus (Mouse) hippo signaling [GO:0035329]; positive regulation of protein phosphorylation [GO:0001934]; regulation of protein autophosphorylation [GO:0031952]; signal transduction [GO:0007165] GO:0001934; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007165; GO:0019209; GO:0019900; GO:0030295; GO:0031952; GO:0035329; GO:0046872 1616 FUN_037492 2890 2721 1383 2327 1511 ptg000026l:11062485-11066895 Q8BPB0 4.09e-22 MOB kinase activator 1B (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A) Mus musculus (Mouse) hippo signaling [GO:0035329]; positive regulation of protein phosphorylation [GO:0001934]; regulation of protein autophosphorylation [GO:0031952]; signal transduction [GO:0007165] GO:0001934; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007165; GO:0019209; GO:0019900; GO:0030295; GO:0031952; GO:0035329; GO:0046872 1617 FUN_037499 1013 884 802 1158 760 NA NA NA NA NA NA NA 1618 FUN_037498 124 12 37 50 9 ptg000026l:11151459-11152851 P58308 7.15e-25 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 1619 FUN_006154 63 15 0 47 16 NA NA NA NA NA NA NA 1620 FUN_006155 0 0 0 28 66 NA NA NA NA NA NA NA 1621 FUN_006156 120 452 54 383 304 NA NA NA NA NA NA NA 1622 FUN_006150 252 16 240 314 0 NA NA NA NA NA NA NA 1623 FUN_006151 760 1062 586 980 1060 NA NA NA NA NA NA NA 1624 FUN_006152 0 2 0 13 0 NA NA NA NA NA NA NA 1625 FUN_006158 16 32 1 4 1 NA NA NA NA NA NA NA 1626 FUN_006159 72 399 316 509 131 NA NA NA NA NA NA NA 1627 FUN_031268 4652 2712 2619 5197 4054 ptg000023l:18723716-18737958 Q9ESM7 9.53e-21 Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L) Mesocricetus auratus (Golden hamster) ERAD pathway [GO:0036503]; Notch signaling pathway [GO:0007219]; protein secretion [GO:0009306]; triglyceride metabolic process [GO:0006641] GO:0000839; GO:0005783; GO:0006641; GO:0007219; GO:0009306; GO:0036503 1628 FUN_031269 622 235 219 330 316 ptg000023l:18741525-18746825 Q3T906 1.72e-173 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta] Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; secretion of lysosomal enzymes [GO:0033299] GO:0000139; GO:0003976; GO:0005509; GO:0005794; GO:0007040; GO:0016256; GO:0033299; GO:0046835; GO:0070622 1629 FUN_031269 622 235 219 330 316 ptg000023l:18741525-18746825 Q3T906 1.74e-55 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta] Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; secretion of lysosomal enzymes [GO:0033299] GO:0000139; GO:0003976; GO:0005509; GO:0005794; GO:0007040; GO:0016256; GO:0033299; GO:0046835; GO:0070622 1630 FUN_031269 622 235 219 330 316 ptg000023l:18741525-18746825 Q3T906 9.52e-35 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (EC 2.7.8.17) (GlcNAc-1-phosphotransferase subunits alpha/beta) (Stealth protein GNPTAB) (UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta) [Cleaved into: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta] Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; lysosome organization [GO:0007040]; N-glycan processing to lysosome [GO:0016256]; secretion of lysosomal enzymes [GO:0033299] GO:0000139; GO:0003976; GO:0005509; GO:0005794; GO:0007040; GO:0016256; GO:0033299; GO:0046835; GO:0070622 1631 FUN_031260 195 187 934 158 464 NA NA NA NA NA NA NA 1632 FUN_031261 53 29 96 52 107 NA NA NA NA NA NA NA 1633 FUN_031262 776 353 324 450 446 NA NA NA NA NA NA NA 1634 FUN_031263 118 99 193 127 204 NA NA NA NA NA NA NA 1635 FUN_031264 23 26 139 178 48 NA NA NA NA NA NA NA 1636 FUN_031266 99 0 1 24 0 NA NA NA NA NA NA NA 1637 FUN_031267 9039 6167 5147 10261 10693 NA NA NA NA NA NA NA 1638 FUN_037149 4 0 0 207 0 NA NA NA NA NA NA NA 1639 FUN_037148 1669 36 30 100 71 ptg000026l:6373727-6377617 Q7Z494 3.48e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 1640 FUN_037148 1669 36 30 100 71 ptg000026l:6373727-6377617 Q7Z494 6.84e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 1641 FUN_037148 1669 36 30 100 71 ptg000026l:6373727-6377617 Q7Z494 8.88e-42 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 1642 FUN_037148 1669 36 30 100 71 ptg000026l:6373727-6377617 Q7Z494 2.2e-39 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 1643 FUN_037146 881 73 150 240 253 ptg000026l:6356835-6361075 P0CI65 5.3e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1644 FUN_037146 881 73 150 240 253 ptg000026l:6356835-6361075 P0CI65 2.22e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1645 FUN_037146 881 73 150 240 253 ptg000026l:6356835-6361075 P0CI65 1.4e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1646 FUN_037146 881 73 150 240 253 ptg000026l:6356835-6361075 P0CI65 2.52e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1647 FUN_037146 881 73 150 240 253 ptg000026l:6356835-6361075 P0CI65 2.3e-37 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1648 FUN_037146 881 73 150 240 253 ptg000026l:6356835-6361075 P0CI65 1.51e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1649 FUN_037145 1902 557 160 542 518 ptg000026l:6327368-6342972 P0CI65 1.37e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1650 FUN_037145 1902 557 160 542 518 ptg000026l:6327368-6342972 P0CI65 1.5e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1651 FUN_037145 1902 557 160 542 518 ptg000026l:6327368-6342972 P0CI65 5.42e-35 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1652 FUN_037144 208 0 0 16 50 NA NA NA NA NA NA NA 1653 FUN_037143 564 450 473 1208 1419 ptg000026l:6304302-6308010 P0CI65 5.92e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1654 FUN_037143 564 450 473 1208 1419 ptg000026l:6304302-6308010 P0CI65 3.12e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1655 FUN_037143 564 450 473 1208 1419 ptg000026l:6304302-6308010 P0CI65 1.18e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 1656 FUN_037141 14 0 2 0 0 NA NA NA NA NA NA NA 1657 FUN_037140 12 95 132 79 137 NA NA NA NA NA NA NA 1658 FUN_032517 1343 843 1455 1197 994 NA NA NA NA NA NA NA 1659 FUN_032516 600 895 448 987 488 NA NA NA NA NA NA NA 1660 FUN_032515 0 169 0 42 63 NA NA NA NA NA NA NA 1661 FUN_032514 0 0 0 0 23 NA NA NA NA NA NA NA 1662 FUN_032513 0 75 27 40 10 NA NA NA NA NA NA NA 1663 FUN_032512 0 0 1 0 6 NA NA NA NA NA NA NA 1664 FUN_032511 0 43 0 19 60 NA NA NA NA NA NA NA 1665 FUN_032510 0 0 0 0 10 NA NA NA NA NA NA NA 1666 FUN_032519 0 58 134 135 77 NA NA NA NA NA NA NA 1667 FUN_042817 7342 4645 3826 7860 7275 NA NA NA NA NA NA NA 1668 FUN_026707 52 0 19 64 30 ptg000020l:12692303-12693038 P9WEL4 8.45e-23 NA NA NA NA 1669 FUN_005860 120 239 60 141 133 NA NA NA NA NA NA NA 1670 FUN_042811 268 269 230 346 336 NA NA NA NA NA NA NA 1671 FUN_042810 4469 4138 2608 3318 2905 NA NA NA NA NA NA NA 1672 FUN_001318 22 0 0 0 0 NA NA NA NA NA NA NA 1673 FUN_001317 483 575 415 453 959 NA NA NA NA NA NA NA 1674 FUN_001316 11073 9667 5532 15663 16181 NA NA NA NA NA NA NA 1675 FUN_001312 367 188 196 338 370 ntLink_6:10994708-11000261 Q9Y3Q0 1.37e-95 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 1676 FUN_001311 271 102 170 336 151 NA NA NA NA NA NA NA 1677 FUN_001310 10245 8846 7506 8055 4601 NA NA NA NA NA NA NA 1678 FUN_033644 52 3 0 0 86 NA NA NA NA NA NA NA 1679 FUN_033645 57 2 24 2 105 NA NA NA NA NA NA NA 1680 FUN_033646 65 2 24 0 115 NA NA NA NA NA NA NA 1681 FUN_004793 1237 1150 777 658 594 NA NA NA NA NA NA NA 1682 FUN_004794 597 911 276 525 473 NA NA NA NA NA NA NA 1683 FUN_033642 0 10 0 0 0 NA NA NA NA NA NA NA 1684 FUN_004797 760 657 357 1083 906 NA NA NA NA NA NA NA 1685 FUN_004798 572 150 348 564 356 ntLink_8:27171042-27172752 Q95M17 4.88e-77 Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04) Bos taurus (Bovine) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] GO:0000272; GO:0002376; GO:0002532; GO:0004568; GO:0005615; GO:0005737; GO:0006032; GO:0006915; GO:0008061; GO:0032722 1686 FUN_004799 65 0 0 61 36 NA NA NA NA NA NA NA 1687 FUN_033648 58 3 20 0 166 NA NA NA NA NA NA NA 1688 FUN_033649 11 0 4 1 30 NA NA NA NA NA NA NA 1689 FUN_002657 344 168 212 322 362 NA NA NA NA NA NA NA 1690 FUN_002656 52 2 26 12 408 NA NA NA NA NA NA NA 1691 FUN_002655 86 102 119 72 22 NA NA NA NA NA NA NA 1692 FUN_002654 255 249 77 111 65 NA NA NA NA NA NA NA 1693 FUN_002653 39 0 0 37 0 NA NA NA NA NA NA NA 1694 FUN_002652 10 0 0 0 0 NA NA NA NA NA NA NA 1695 FUN_002650 376 154 141 253 218 NA NA NA NA NA NA NA 1696 FUN_002659 112 57 78 121 92 NA NA NA NA NA NA NA 1697 FUN_002658 2150 1432 998 2422 2086 NA NA NA NA NA NA NA 1698 FUN_019274 30 71 0 0 110 NA NA NA NA NA NA NA 1699 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 1.87e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1700 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 6.66e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1701 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 2.8e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1702 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 1.57e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1703 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 2.64e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1704 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 8.34e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1705 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 6.75e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1706 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 1.45e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1707 FUN_018348 1609 8 520 20 56 ptg000012l:8056034-8075645 Q96AY4 6.38e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1708 FUN_018349 865 270 1131 2232 289 NA NA NA NA NA NA NA 1709 FUN_018343 289 43 84 226 70 NA NA NA NA NA NA NA 1710 FUN_018340 7 0 0 3 3 NA NA NA NA NA NA NA 1711 FUN_018341 89 12 45 90 54 NA NA NA NA NA NA NA 1712 FUN_018346 1028 82 763 320 271 NA NA NA NA NA NA NA 1713 FUN_018347 45 0 25 0 12 NA NA NA NA NA NA NA 1714 FUN_018344 211 118 149 147 91 NA NA NA NA NA NA NA 1715 FUN_018345 7 0 18 20 2 NA NA NA NA NA NA NA 1716 FUN_012700 870 847 328 155 338 ptg000008l:11500898-11507365 Q12794 1.38e-29 Hyaluronidase-1 (Hyal-1) (EC 3.2.1.35) (Hyaluronoglucosaminidase-1) (Lung carcinoma protein 1) (LuCa-1) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to pH [GO:0071467]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to UV-B [GO:0071493]; chondroitin sulfate catabolic process [GO:0030207]; embryonic skeletal joint morphogenesis [GO:0060272]; hyaluronan biosynthetic process [GO:0030213]; hyaluronan catabolic process [GO:0030214]; hyaluronan metabolic process [GO:0030212]; inflammatory response [GO:0006954]; negative regulation of cell growth [GO:0030308]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of growth [GO:0045927]; positive regulation of hyaluranon cable assembly [GO:1900106]; response to antibiotic [GO:0046677]; response to reactive oxygen species [GO:0000302]; response to virus [GO:0009615] GO:0000302; GO:0004415; GO:0005615; GO:0005737; GO:0005764; GO:0005975; GO:0006954; GO:0009615; GO:0010634; GO:0030207; GO:0030212; GO:0030213; GO:0030214; GO:0030307; GO:0030308; GO:0031410; GO:0036117; GO:0036120; GO:0043202; GO:0044344; GO:0045766; GO:0045785; GO:0045927; GO:0046677; GO:0050501; GO:0050679; GO:0051216; GO:0052757; GO:0060272; GO:0070062; GO:0071347; GO:0071356; GO:0071467; GO:0071493; GO:1900087; GO:1900106 1717 FUN_012701 2257 977 943 1719 1381 NA NA NA NA NA NA NA 1718 FUN_012702 757 233 300 609 309 NA NA NA NA NA NA NA 1719 FUN_012703 1663 788 787 1606 1337 NA NA NA NA NA NA NA 1720 FUN_012704 27 0 0 0 12 NA NA NA NA NA NA NA 1721 FUN_012705 8821 11825 7850 14329 6239 NA NA NA NA NA NA NA 1722 FUN_012706 2336 2246 1140 2494 1717 NA NA NA NA NA NA NA 1723 FUN_012707 573 381 250 292 372 ptg000008l:11586146-11587181 A7YY53 8.34e-85 Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.13) (EC 3.6.1.16) (EC 3.6.1.53) (ADPRibase-Mn) (CDP-choline phosphohydrolase) Bos taurus (Bovine) NA GO:0008663; GO:0030145; GO:0047631; GO:0047734 1724 FUN_012708 28 28 7 30 55 NA NA NA NA NA NA NA 1725 FUN_012709 157 105 123 160 90 ptg000008l:11606839-11609743 Q9JHE4 3.45e-54 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 1726 FUN_016410 78 57 18 54 129 NA NA NA NA NA NA NA 1727 FUN_016412 1009 1432 368 974 931 NA NA NA NA NA NA NA 1728 FUN_016413 94 132 15 66 15 NA NA NA NA NA NA NA 1729 FUN_016414 1732 991 823 796 849 NA NA NA NA NA NA NA 1730 FUN_016415 807 110 61 134 149 NA NA NA NA NA NA NA 1731 FUN_016416 94 113 122 43 51 NA NA NA NA NA NA NA 1732 FUN_016417 299 176 35 152 184 NA NA NA NA NA NA NA 1733 FUN_016418 7 80 21 99 59 NA NA NA NA NA NA NA 1734 FUN_016419 9435 9710 5230 10546 4611 NA NA NA NA NA NA NA 1735 FUN_006938 381 257 293 1026 856 NA NA NA NA NA NA NA 1736 FUN_006939 451 513 608 887 1070 NA NA NA NA NA NA NA 1737 FUN_040881 0 0 0 4 10 NA NA NA NA NA NA NA 1738 FUN_040884 2 0 5 0 16 NA NA NA NA NA NA NA 1739 FUN_040885 0 7 4 2 12 NA NA NA NA NA NA NA 1740 FUN_040887 18 0 36 0 111 NA NA NA NA NA NA NA 1741 FUN_040888 922 10 73 1331 646 NA NA NA NA NA NA NA 1742 FUN_018446 172 67 38 58 6 NA NA NA NA NA NA NA 1743 FUN_010922 0 173 4 247 310 NA NA NA NA NA NA NA 1744 FUN_035178 5132 1355 2413 2645 974 NA NA NA NA NA NA NA 1745 FUN_035179 92 21 41 3 17 NA NA NA NA NA NA NA 1746 FUN_043718 0 16 8 0 8 NA NA NA NA NA NA NA 1747 FUN_035174 2026 1624 397 2370 1115 ptg000025l:4733933-4741791 Q3T052 8.68e-75 Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) Bos taurus (Bovine) acute-phase response [GO:0006953]; hyaluronan metabolic process [GO:0030212]; negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0006953; GO:0010466; GO:0030212 1748 FUN_035175 0 12 5 326 93 NA NA NA NA NA NA NA 1749 FUN_035176 236 264 82 738 98 NA NA NA NA NA NA NA 1750 FUN_035177 3064 1625 1841 2566 2645 ptg000025l:4786694-4816356 Q9WTZ3 2.87e-33 Membrane-bound transcription factor site-1 protease (EC 3.4.21.112) (Endopeptidase S1P) (Subtilisin/kexin isozyme 1) (SKI-1) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; lipid metabolic process [GO:0006629]; lysosome organization [GO:0007040]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of vesicle-mediated transport [GO:0060627] GO:0000139; GO:0004252; GO:0005789; GO:0005794; GO:0005795; GO:0006508; GO:0006629; GO:0007040; GO:0008203; GO:0016485; GO:0060627 1751 FUN_035170 1737 1874 666 1812 1015 NA NA NA NA NA NA NA 1752 FUN_035171 1113 572 891 479 471 NA NA NA NA NA NA NA 1753 FUN_035172 366 266 159 237 196 ptg000025l:4728745-4729595 S4R2K0 7.96e-45 Peptide deformylase, mitochondrial (EC 3.5.1.88) (Polypeptide deformylase) Mus musculus (Mouse) co-translational protein modification [GO:0043686]; N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; positive regulation of cell population proliferation [GO:0008284]; translation [GO:0006412] GO:0005739; GO:0006412; GO:0008284; GO:0018206; GO:0031365; GO:0042586; GO:0043686; GO:0046872 1754 FUN_035173 262 442 138 962 423 NA NA NA NA NA NA NA 1755 FUN_042818 16 0 0 6 42 NA NA NA NA NA NA NA 1756 FUN_010921 4603 3553 680 2395 639 NA NA NA NA NA NA NA 1757 FUN_010924 1802 592 245 202 329 ptg000007l:4293710-4343874 P21328 2.27e-36 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 1758 FUN_010925 793 340 406 885 548 NA NA NA NA NA NA NA 1759 FUN_043289 2008 757 1172 2390 1297 NA NA NA NA NA NA NA 1760 FUN_043287 771 1120 569 572 575 NA NA NA NA NA NA NA 1761 FUN_043286 15311 14276 7220 9950 6353 ptg000047l:6375961-6380993 Q5ZKN1 3.36e-131 Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 9) Gallus gallus (Chicken) positive regulation of protein localization to chromatin [GO:0120187]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein phosphorylation [GO:0006468]; transcription by RNA polymerase II [GO:0006366] GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0006366; GO:0006468; GO:0008353; GO:0016592; GO:0032968; GO:0045944; GO:0070691; GO:0106310; GO:0120187 1762 FUN_043285 207 362 219 371 350 NA NA NA NA NA NA NA 1763 FUN_043284 8 0 0 0 18 NA NA NA NA NA NA NA 1764 FUN_043283 415 272 143 241 167 NA NA NA NA NA NA NA 1765 FUN_010928 840 425 169 786 760 NA NA NA NA NA NA NA 1766 FUN_043281 497 590 482 646 811 NA NA NA NA NA NA NA 1767 FUN_043280 6 2 0 0 0 NA NA NA NA NA NA NA 1768 FUN_028770 10 12 19 19 39 NA NA NA NA NA NA NA 1769 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 1.65e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1770 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 2.24e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1771 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 1.75e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1772 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 2.89e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1773 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 3e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1774 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 3.53e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1775 FUN_028771 0 0 0 0 12 ptg000022l:3721615-3724380 Q96AY4 1.51e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1776 FUN_028773 0 39 14 4 0 NA NA NA NA NA NA NA 1777 FUN_028774 0 21 123 22 53 NA NA NA NA NA NA NA 1778 FUN_013077 75 116 28 108 136 NA NA NA NA NA NA NA 1779 FUN_013076 0 0 18 0 55 NA NA NA NA NA NA NA 1780 FUN_013079 1783 1086 812 1592 963 NA NA NA NA NA NA NA 1781 FUN_013078 125 0 117 147 130 NA NA NA NA NA NA NA 1782 FUN_018057 117 33 0 0 0 NA NA NA NA NA NA NA 1783 FUN_040490 3682 4408 3033 3812 2291 ptg000031l:9284464-9295392 P62315 8.94e-24 Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000243; GO:0000387; GO:0000398; GO:0003723; GO:0005634; GO:0005681; GO:0005682; GO:0005685; GO:0005686; GO:0005687; GO:0005689; GO:0005737; GO:0005829; GO:0034709; GO:0034715; GO:0034719; GO:0046540; GO:0071005; GO:0071007; GO:0071011; GO:0071013; GO:0097526; GO:1990446 1784 FUN_003889 62 201 52 84 29 ntLink_8:16535144-16536028 B8VIU6 2.64e-34 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 1785 FUN_042627 88 0 94 0 361 NA NA NA NA NA NA NA 1786 FUN_042624 14731 5237 11286 21941 25051 NA NA NA NA NA NA NA 1787 FUN_042625 9 10 9 14 17 NA NA NA NA NA NA NA 1788 FUN_042622 1486 760 612 1219 1122 NA NA NA NA NA NA NA 1789 FUN_042623 499 200 440 755 791 ptg000039l:484510-485740 Q05D32 1.4e-120 CTD small phosphatase-like protein 2 (CTDSP-like 2) (EC 3.1.3.-) Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of protein export from nucleus [GO:0046827]; protein dephosphorylation [GO:0006470]; protein export from nucleus [GO:0006611] GO:0004721; GO:0005654; GO:0006470; GO:0006611; GO:0008420; GO:0030514; GO:0046827 1790 FUN_042620 43667 11393 17458 27815 7667 NA NA NA NA NA NA NA 1791 FUN_042621 23 2 5442 9 198 NA NA NA NA NA NA NA 1792 FUN_003881 1032 496 501 353 348 NA NA NA NA NA NA NA 1793 FUN_003880 269 146 82 45 101 NA NA NA NA NA NA NA 1794 FUN_003883 0 0 12 26 32 NA NA NA NA NA NA NA 1795 FUN_003882 521 809 151 1946 446 NA NA NA NA NA NA NA 1796 FUN_003885 0 20 0 41 20 ntLink_8:16486205-16492093 Q9Z2E3 7.21e-27 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 1797 FUN_003884 0 8 0 26 20 NA NA NA NA NA NA NA 1798 FUN_042628 30 70 105 24 46 NA NA NA NA NA NA NA 1799 FUN_003886 1274 998 684 1626 1115 NA NA NA NA NA NA NA 1800 FUN_012332 745 559 923 777 1018 NA NA NA NA NA NA NA 1801 FUN_012335 1872 1493 1039 936 343 NA NA NA NA NA NA NA 1802 FUN_002132 0 0 0 0 135 NA NA NA NA NA NA NA 1803 FUN_009301 2077 789 979 1366 1578 NA NA NA NA NA NA NA 1804 FUN_002130 0 22 0 4 0 NA NA NA NA NA NA NA 1805 FUN_006140 0 0 17 0 44 ptg000001l:8276165-8310705 B8V7S0 7.05e-92 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 1806 FUN_009306 136 118 61 234 35 NA NA NA NA NA NA NA 1807 FUN_009307 882 0 0 7 140 NA NA NA NA NA NA NA 1808 FUN_009308 14762 12004 9480 19091 14937 ptg000004l:5154366-5165297 Q9ZE33 1.8e-21 NADH-quinone oxidoreductase subunit F (EC 7.1.1.-) (NADH dehydrogenase I subunit F) (NDH-1 subunit F) Rickettsia prowazekii (strain Madrid E) NA GO:0008137; GO:0010181; GO:0045271; GO:0046872; GO:0048038; GO:0051287; GO:0051539 1809 FUN_009309 1062 1127 315 338 307 NA NA NA NA NA NA NA 1810 FUN_002138 0 0 15 37 0 NA NA NA NA NA NA NA 1811 FUN_002139 0 0 5 16 0 NA NA NA NA NA NA NA 1812 FUN_030187 77 0 30 0 43 NA NA NA NA NA NA NA 1813 FUN_043018 379 115 190 348 347 NA NA NA NA NA NA NA 1814 FUN_012183 575 272 567 542 1402 ptg000008l:6136224-6159252 Q13315 1.42e-25 Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated) Homo sapiens (Human) brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to nitrosative stress [GO:0071500]; cellular response to retinoic acid [GO:0071300]; cellular response to X-ray [GO:0071481]; cellular senescence [GO:0090398]; determination of adult lifespan [GO:0008340]; DNA damage checkpoint signaling [GO:0000077]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; establishment of protein-containing complex localization to telomere [GO:0097695]; establishment of RNA localization to telomere [GO:0097694]; female meiotic nuclear division [GO:0007143]; heart development [GO:0007507]; histone mRNA catabolic process [GO:0071044]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; lipoprotein catabolic process [GO:0042159]; male meiotic nuclear division [GO:0007140]; meiotic telomere clustering [GO:0045141]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic spindle assembly checkpoint signaling [GO:0007094]; multicellular organism growth [GO:0035264]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of telomere capping [GO:1904354]; negative regulation of TORC1 signaling [GO:1904262]; neuron apoptotic process [GO:0051402]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; pexophagy [GO:0000425]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA catabolic process [GO:1903626]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; pre-B cell allelic exclusion [GO:0002331]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; reciprocal meiotic recombination [GO:0007131]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of cell cycle [GO:0051726]; regulation of cellular response to gamma radiation [GO:1905843]; regulation of cellular response to heat [GO:1900034]; regulation of microglial cell activation [GO:1903978]; regulation of signal transduction by p53 class mediator [GO:1901796]; regulation of telomere maintenance via telomerase [GO:0032210]; replicative senescence [GO:0090399]; response to hypoxia [GO:0001666]; response to ionizing radiation [GO:0010212]; signal transduction [GO:0007165]; signal transduction in response to DNA damage [GO:0042770]; somitogenesis [GO:0001756]; telomere maintenance [GO:0000723]; thymus development [GO:0048538]; V(D)J recombination [GO:0033151] GO:0000077; GO:0000425; GO:0000723; GO:0000724; GO:0001541; GO:0001666; GO:0001756; GO:0002331; GO:0003677; GO:0004674; GO:0004677; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005782; GO:0005813; GO:0005819; GO:0005829; GO:0006302; GO:0006303; GO:0006468; GO:0006974; GO:0006977; GO:0007094; GO:0007095; GO:0007131; GO:0007140; GO:0007143; GO:0007165; GO:0007420; GO:0007507; GO:0008340; GO:0008630; GO:0009791; GO:0010212; GO:0010506; GO:0010628; GO:0016303; GO:0018105; GO:0030335; GO:0030889; GO:0031410; GO:0032210; GO:0032212; GO:0033151; GO:0035264; GO:0036289; GO:0042159; GO:0042770; GO:0042802; GO:0042981; GO:0043065; GO:0043231; GO:0043517; GO:0043525; GO:0044877; GO:0045141; GO:0045785; GO:0045944; GO:0046777; GO:0047485; GO:0048538; GO:0048599; GO:0051402; GO:0051726; GO:0071044; GO:0071300; GO:0071480; GO:0071481; GO:0071500; GO:0090398; GO:0090399; GO:0097694; GO:0097695; GO:0106310; GO:1900034; GO:1901796; GO:1903626; GO:1903978; GO:1904262; GO:1904354; GO:1904358; GO:1904884; GO:1905843; GO:1990391 1815 FUN_007932 4309 4556 1242 3273 890 NA NA NA NA NA NA NA 1816 FUN_022637 101 61 33 108 137 ptg000016l:11743974-11745398 Q6DJM2 6.83e-96 Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41) Xenopus laevis (African clawed frog) cardiolipin biosynthetic process [GO:0032049]; CDP-diacylglycerol biosynthetic process [GO:0016024] GO:0004605; GO:0005743; GO:0016024; GO:0019898; GO:0031314; GO:0032049 1817 FUN_022636 99 0 6 120 139 NA NA NA NA NA NA NA 1818 FUN_022635 828 482 405 315 664 NA NA NA NA NA NA NA 1819 FUN_022634 1219 636 679 1410 973 ptg000016l:11696270-11724059 Q6INC1 2.22e-27 Tetratricopeptide repeat protein 21B (TPR repeat protein 21B) Xenopus laevis (African clawed frog) NA GO:0030991 1820 FUN_022633 1199 669 647 828 933 ptg000016l:11677774-11692198 Q5R9A7 4.96e-28 Integral membrane protein GPR155 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] GO:0016020; GO:0035556; GO:0055085 1821 FUN_022633 1199 669 647 828 933 ptg000016l:11677774-11692198 Q5R9A7 9.04e-21 Integral membrane protein GPR155 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) intracellular signal transduction [GO:0035556]; transmembrane transport [GO:0055085] GO:0016020; GO:0035556; GO:0055085 1822 FUN_022632 2794 2599 709 731 1620 NA NA NA NA NA NA NA 1823 FUN_022631 291 207 327 390 432 ptg000016l:11652770-11654210 P25931 2.55e-29 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 1824 FUN_022630 4578 2375 2417 3993 3275 NA NA NA NA NA NA NA 1825 FUN_022639 3556 1556 2007 2159 1717 NA NA NA NA NA NA NA 1826 FUN_022638 772 892 283 441 467 NA NA NA NA NA NA NA 1827 FUN_040718 13 0 0 96 63 NA NA NA NA NA NA NA 1828 FUN_040719 0 0 8 0 0 NA NA NA NA NA NA NA 1829 FUN_040710 5193 2737 1322 10338 7967 ptg000031l:12259051-12265150 P47236 5.65e-42 Paired box protein Pax-1 Gallus gallus (Chicken) anatomical structure development [GO:0048856]; regulation of transcription by RNA polymerase II [GO:0006357]; sclerotome development [GO:0061056] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0048856; GO:0061056 1830 FUN_040711 964 516 284 2040 1580 ptg000031l:12266175-12270564 P47236 5.41e-41 Paired box protein Pax-1 Gallus gallus (Chicken) anatomical structure development [GO:0048856]; regulation of transcription by RNA polymerase II [GO:0006357]; sclerotome development [GO:0061056] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0048856; GO:0061056 1831 FUN_040712 11793 9176 4768 7792 5212 NA NA NA NA NA NA NA 1832 FUN_036809 901 1141 652 1046 840 NA NA NA NA NA NA NA 1833 FUN_012889 949 3083 844 109 1754 NA NA NA NA NA NA NA 1834 FUN_012887 0 12 0 0 0 NA NA NA NA NA NA NA 1835 FUN_028084 662 537 635 559 445 ptg000021l:15629314-15651599 Q63120 2.86e-27 ATP-binding cassette sub-family C member 2 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multidrug resistance protein) (Canalicular multispecific organic anion transporter 1) (Multidrug resistance-associated protein 2) Rattus norvegicus (Rat) antibiotic metabolic process [GO:0016999]; benzylpenicillin metabolic process [GO:1901086]; bile acid and bile salt transport [GO:0015721]; bile acid signaling pathway [GO:0038183]; bilirubin transport [GO:0015723]; canalicular bile acid transport [GO:0015722]; cellular chloride ion homeostasis [GO:0030644]; cellular response to dexamethasone stimulus [GO:0071549]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to xenobiotic stimulus [GO:0071466]; detoxification of mercury ion [GO:0050787]; female pregnancy [GO:0007565]; inflammatory response [GO:0006954]; leukotriene transport [GO:0071716]; mercury ion transport [GO:0015694]; negative regulation of gene expression [GO:0010629]; organic anion transport [GO:0015711]; prostaglandin transport [GO:0015732]; regulation of bile acid secretion [GO:0120188]; regulation of gene expression [GO:0010468]; response to 17alpha-ethynylestradiol [GO:1904486]; response to antineoplastic agent [GO:0097327]; response to arsenic-containing substance [GO:0046685]; response to estradiol [GO:0032355]; response to estrogen [GO:0043627]; response to glucagon [GO:0033762]; response to heat [GO:0009408]; response to lipopolysaccharide [GO:0032496]; response to organic cyclic compound [GO:0014070]; response to oxidative stress [GO:0006979]; response to steroid hormone [GO:0048545]; response to xenobiotic stimulus [GO:0009410]; thyroid hormone transport [GO:0070327]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; xenobiotic catabolic process [GO:0042178]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0005737; GO:0005886; GO:0006855; GO:0006954; GO:0006979; GO:0007565; GO:0008514; GO:0008559; GO:0009408; GO:0009410; GO:0009986; GO:0010468; GO:0010629; GO:0014070; GO:0015127; GO:0015431; GO:0015694; GO:0015711; GO:0015721; GO:0015722; GO:0015723; GO:0015732; GO:0016020; GO:0016324; GO:0016887; GO:0016999; GO:0019904; GO:0030644; GO:0031526; GO:0032355; GO:0032496; GO:0033762; GO:0038183; GO:0042178; GO:0042626; GO:0042910; GO:0043627; GO:0046581; GO:0046618; GO:0046685; GO:0046691; GO:0048545; GO:0050787; GO:0055085; GO:0070327; GO:0070633; GO:0071222; GO:0071347; GO:0071354; GO:0071356; GO:0071466; GO:0071549; GO:0071716; GO:0097327; GO:0120188; GO:1901086; GO:1904486; GO:1990961; GO:1990962 1836 FUN_012880 1552 2072 906 1023 824 NA NA NA NA NA NA NA 1837 FUN_023057 371 156 130 240 110 NA NA NA NA NA NA NA 1838 FUN_023050 2106 1554 668 2037 1394 ptg000017l:3034503-3042026 Q6NUB7 7.29e-64 Ubiquitin thioesterase zranb1-B (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1B) Xenopus laevis (African clawed frog) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005634; GO:0005737; GO:0007010; GO:0016055; GO:0016477; GO:0022604; GO:0030177; GO:0035523; GO:0046872; GO:0070536; GO:1990168 1839 FUN_023050 2106 1554 668 2037 1394 ptg000017l:3034503-3042026 Q6NUB7 4.08e-27 Ubiquitin thioesterase zranb1-B (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1B) Xenopus laevis (African clawed frog) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005634; GO:0005737; GO:0007010; GO:0016055; GO:0016477; GO:0022604; GO:0030177; GO:0035523; GO:0046872; GO:0070536; GO:1990168 1840 FUN_023050 2106 1554 668 2037 1394 ptg000017l:3034503-3042026 Q6NUB7 7.74e-26 Ubiquitin thioesterase zranb1-B (EC 3.4.19.12) (Zinc finger Ran-binding domain-containing protein 1B) Xenopus laevis (African clawed frog) cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; positive regulation of Wnt signaling pathway [GO:0030177]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K63-linked deubiquitination [GO:0070536]; regulation of cell morphogenesis [GO:0022604]; Wnt signaling pathway [GO:0016055] GO:0004843; GO:0005634; GO:0005737; GO:0007010; GO:0016055; GO:0016477; GO:0022604; GO:0030177; GO:0035523; GO:0046872; GO:0070536; GO:1990168 1841 FUN_028083 3674 1872 2036 2744 2521 ptg000021l:15601373-15622437 Q8HXQ5 7.77e-25 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Bos taurus (Bovine) export across plasma membrane [GO:0140115]; glutathione transmembrane transport [GO:0034775]; leukotriene transport [GO:0071716]; phospholipid translocation [GO:0045332]; positive regulation of inflammatory response [GO:0050729]; response to xenobiotic stimulus [GO:0009410]; sphingolipid translocation [GO:0099039]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0008559; GO:0009410; GO:0015431; GO:0015562; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0016887; GO:0034040; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0042910; GO:0045332; GO:0046943; GO:0050729; GO:0055085; GO:0070633; GO:0071716; GO:0099039; GO:0140115; GO:0140359; GO:1990962 1842 FUN_028083 3674 1872 2036 2744 2521 ptg000021l:15601373-15622437 Q8HXQ5 4.08e-24 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Bos taurus (Bovine) export across plasma membrane [GO:0140115]; glutathione transmembrane transport [GO:0034775]; leukotriene transport [GO:0071716]; phospholipid translocation [GO:0045332]; positive regulation of inflammatory response [GO:0050729]; response to xenobiotic stimulus [GO:0009410]; sphingolipid translocation [GO:0099039]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; xenobiotic transport [GO:0042908]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005524; GO:0008559; GO:0009410; GO:0015431; GO:0015562; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0016887; GO:0034040; GO:0034634; GO:0034775; GO:0042626; GO:0042908; GO:0042910; GO:0045332; GO:0046943; GO:0050729; GO:0055085; GO:0070633; GO:0071716; GO:0099039; GO:0140115; GO:0140359; GO:1990962 1843 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 5.8e-34 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1844 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 5.8e-34 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1845 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 1.83e-31 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1846 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 1.83e-31 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1847 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 1.58e-27 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1848 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 1.69e-26 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1849 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 3.8e-26 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1850 FUN_028266 26 0 17 0 100 ptg000021l:17426918-17441918 Q8TE73 6.07e-23 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 1851 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 7.94e-79 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1852 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 7.94e-79 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1853 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 1.41e-37 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1854 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 5.35e-33 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1855 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 5.35e-33 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1856 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 1.28e-32 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1857 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 4.54e-31 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1858 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 5.31e-30 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1859 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 8.81e-28 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1860 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 1.58e-26 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1861 FUN_028267 68 0 173 29 170 ptg000021l:17442317-17475615 Q96JB1 2.17e-22 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 1862 FUN_010793 91 0 25 0 25 ptg000007l:2892950-2900039 A0A1Y9G8H0 2.73e-33 NA NA NA NA 1863 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 5.43e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1864 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 6.54e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1865 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 7.14e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1866 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 1.36e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1867 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 3.7e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1868 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 8.12e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1869 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 2.77e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1870 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 6.61e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1871 FUN_009876 304 458 132 51 197 ptg000004l:12926866-12934843 Q96AY4 8.87e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 1872 FUN_009874 0 0 0 0 11 NA NA NA NA NA NA NA 1873 FUN_009875 72 0 75 0 34 NA NA NA NA NA NA NA 1874 FUN_009872 71 0 0 44 0 NA NA NA NA NA NA NA 1875 FUN_009873 42 8 26 19 23 ptg000004l:12891037-12893293 Q80XJ3 1.45e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1876 FUN_009873 42 8 26 19 23 ptg000004l:12891037-12893293 Q80XJ3 9.2e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1877 FUN_009873 42 8 26 19 23 ptg000004l:12891037-12893293 Q80XJ3 4.76e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1878 FUN_009873 42 8 26 19 23 ptg000004l:12891037-12893293 Q80XJ3 6.78e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1879 FUN_009873 42 8 26 19 23 ptg000004l:12891037-12893293 Q80XJ3 5.61e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1880 FUN_009873 42 8 26 19 23 ptg000004l:12891037-12893293 Q80XJ3 1.02e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 1881 FUN_009870 26 25 25 86 0 NA NA NA NA NA NA NA 1882 FUN_009871 7 55 12 169 0 NA NA NA NA NA NA NA 1883 FUN_010795 54 38 111 33 35 ptg000007l:2922092-2928205 A4IGL7 2.64e-29 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 1884 FUN_009878 161 169 145 203 100 ptg000004l:12950674-12951016 Q6ING9 3.28e-29 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Xenopus laevis (African clawed frog) protein dephosphorylation [GO:0006470] GO:0005759; GO:0006470; GO:0017018; GO:0046872 1885 FUN_010794 256 1053 97 236 496 ptg000007l:2913775-2918717 B3A0Q8 8.92e-30 Peroxidase-like protein 3 Lottia gigantea (Giant owl limpet) response to oxidative stress [GO:0006979] GO:0004601; GO:0005576; GO:0006979; GO:0020037 1886 FUN_023058 75 77 88 60 21 NA NA NA NA NA NA NA 1887 FUN_010796 546 167 205 272 325 ptg000007l:2930916-2935449 Q7ZTL7 1.51e-77 Mitochondrial chaperone BCS1 (BCS1-like protein) Xenopus laevis (African clawed frog) NA GO:0005524; GO:0005743; GO:0016887 1888 FUN_010796 546 167 205 272 325 ptg000007l:2930916-2935449 Q7ZTL7 1.33e-33 Mitochondrial chaperone BCS1 (BCS1-like protein) Xenopus laevis (African clawed frog) NA GO:0005524; GO:0005743; GO:0016887 1889 FUN_029919 6 12 12 0 0 NA NA NA NA NA NA NA 1890 FUN_032258 0 0 0 176 281 NA NA NA NA NA NA NA 1891 FUN_032259 10 2 0 197 507 NA NA NA NA NA NA NA 1892 FUN_032254 6 0 0 0 31 NA NA NA NA NA NA NA 1893 FUN_029912 8 2 4 7 29 NA NA NA NA NA NA NA 1894 FUN_029911 16 7 0 2 16 NA NA NA NA NA NA NA 1895 FUN_032257 0 0 33 0 18 ptg000023l:30280381-30281475 Q9MYM7 6.63e-28 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 1896 FUN_029917 0 0 0 0 29 NA NA NA NA NA NA NA 1897 FUN_032251 16 29 0 24 4 NA NA NA NA NA NA NA 1898 FUN_032252 3271 2954 2067 4154 2769 NA NA NA NA NA NA NA 1899 FUN_032253 2203 1838 1503 1167 914 NA NA NA NA NA NA NA 1900 FUN_011349 90 174 57 92 0 NA NA NA NA NA NA NA 1901 FUN_011348 0 0 18 0 44 NA NA NA NA NA NA NA 1902 FUN_011341 52 8 66 5 448 NA NA NA NA NA NA NA 1903 FUN_011340 0 0 0 0 33 NA NA NA NA NA NA NA 1904 FUN_011347 12 0 0 0 14 NA NA NA NA NA NA NA 1905 FUN_013433 0 99 0 0 0 NA NA NA NA NA NA NA 1906 FUN_000518 48944 36306 32149 57117 59518 ntLink_6:3891439-3902167 P17336 1.82e-39 Catalase (EC 1.11.1.6) Drosophila melanogaster (Fruit fly) aging [GO:0007568]; determination of adult lifespan [GO:0008340]; heart morphogenesis [GO:0003007]; hydrogen peroxide catabolic process [GO:0042744]; intestinal stem cell homeostasis [GO:0036335]; paracrine signaling [GO:0038001]; reactive oxygen species metabolic process [GO:0072593]; regulation of hemocyte proliferation [GO:0035206]; regulation of synaptic plasticity [GO:0048167]; response to endoplasmic reticulum stress [GO:0034976]; response to hydrogen peroxide [GO:0042542] GO:0003007; GO:0004096; GO:0005737; GO:0005739; GO:0005777; GO:0007568; GO:0008340; GO:0020037; GO:0034976; GO:0035206; GO:0036335; GO:0038001; GO:0042542; GO:0042744; GO:0046872; GO:0048167; GO:0072593 1907 FUN_000518 48944 36306 32149 57117 59518 ntLink_6:3891439-3902167 P17336 6.37e-22 Catalase (EC 1.11.1.6) Drosophila melanogaster (Fruit fly) aging [GO:0007568]; determination of adult lifespan [GO:0008340]; heart morphogenesis [GO:0003007]; hydrogen peroxide catabolic process [GO:0042744]; intestinal stem cell homeostasis [GO:0036335]; paracrine signaling [GO:0038001]; reactive oxygen species metabolic process [GO:0072593]; regulation of hemocyte proliferation [GO:0035206]; regulation of synaptic plasticity [GO:0048167]; response to endoplasmic reticulum stress [GO:0034976]; response to hydrogen peroxide [GO:0042542] GO:0003007; GO:0004096; GO:0005737; GO:0005739; GO:0005777; GO:0007568; GO:0008340; GO:0020037; GO:0034976; GO:0035206; GO:0036335; GO:0038001; GO:0042542; GO:0042744; GO:0046872; GO:0048167; GO:0072593 1908 FUN_000519 465 207 227 895 300 NA NA NA NA NA NA NA 1909 FUN_000512 0 0 0 33 58 NA NA NA NA NA NA NA 1910 FUN_000510 984 523 351 1314 1172 NA NA NA NA NA NA NA 1911 FUN_000511 145 105 113 209 299 NA NA NA NA NA NA NA 1912 FUN_000516 38 73 30 37 11 NA NA NA NA NA NA NA 1913 FUN_000517 0 9 0 9 0 NA NA NA NA NA NA NA 1914 FUN_000514 27 0 11 0 209 NA NA NA NA NA NA NA 1915 FUN_000515 28 6 2 0 27 NA NA NA NA NA NA NA 1916 FUN_014834 125 32 77 120 190 ptg000009l:3528493-3532348 Q8VHI5 2.69e-21 Vitrin (Akhirin) Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]; spinal cord development [GO:0021510] GO:0005539; GO:0005576; GO:0005614; GO:0010811; GO:0021510; GO:0030198; GO:0031012; GO:0062023 1917 FUN_014835 505 228 179 770 755 NA NA NA NA NA NA NA 1918 FUN_014830 57 32 17 102 148 ptg000009l:3502504-3516977 Q99715 1.41e-26 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 1919 FUN_014830 57 32 17 102 148 ptg000009l:3502504-3516977 Q99715 8.5e-24 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 1920 FUN_014830 57 32 17 102 148 ptg000009l:3502504-3516977 Q99715 5.2e-23 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 1921 FUN_014832 0 0 11 25 0 NA NA NA NA NA NA NA 1922 FUN_014833 0 0 0 29 0 ptg000009l:3521958-3526835 P84552 3.75e-23 Cochlin (COCH-5B2) Cavia porcellus (Guinea pig) NA GO:0005518; GO:0005576; GO:0062023 1923 FUN_014838 4 3 16 16 1 NA NA NA NA NA NA NA 1924 FUN_013828 719 486 192 606 382 NA NA NA NA NA NA NA 1925 FUN_013829 0 18 13 0 21 NA NA NA NA NA NA NA 1926 FUN_020962 0 0 0 0 7 NA NA NA NA NA NA NA 1927 FUN_020964 0 0 9 0 111 NA NA NA NA NA NA NA 1928 FUN_020968 0 0 0 16 24 NA NA NA NA NA NA NA 1929 FUN_013290 199 16 9 248 249 ptg000008l:20527399-20529381 Q0V8L6 1.12e-98 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 1930 FUN_013290 199 16 9 248 249 ptg000008l:20527399-20529381 Q0V8L6 1.12e-98 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 1931 FUN_028552 193 100 66 89 102 NA NA NA NA NA NA NA 1932 FUN_028553 2640 1666 1934 2701 2420 NA NA NA NA NA NA NA 1933 FUN_028554 11931 6245 4674 10068 7637 NA NA NA NA NA NA NA 1934 FUN_013294 0 0 23 0 7 NA NA NA NA NA NA NA 1935 FUN_012069 117 313 78 160 178 NA NA NA NA NA NA NA 1936 FUN_012068 264 99 197 351 366 ptg000008l:4793931-4805254 O75762 1.79e-26 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 1937 FUN_013297 131 409 466 148 129 NA NA NA NA NA NA NA 1938 FUN_012061 0 11 0 0 0 NA NA NA NA NA NA NA 1939 FUN_012060 1 12 0 0 13 ptg000008l:4723757-4726494 Q20201 5.49e-24 Transcription factor sox-3 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0030182; GO:0043565 1940 FUN_012063 53 48 6 0 17 NA NA NA NA NA NA NA 1941 FUN_012062 50 43 16 31 30 NA NA NA NA NA NA NA 1942 FUN_012065 17 0 0 16 85 NA NA NA NA NA NA NA 1943 FUN_012064 0 3 0 11 33 NA NA NA NA NA NA NA 1944 FUN_012067 310 207 251 1500 2227 NA NA NA NA NA NA NA 1945 FUN_012066 272 112 124 511 251 ptg000008l:4769031-4780955 O75762 9.02e-24 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation-sensitive protein p120) (p120) (Wasabi receptor) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transport [GO:0006811]; protein homotetramerization [GO:0051289]; response to cold [GO:0009409]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0015267; GO:0015278; GO:0019233; GO:0032421; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0051289; GO:0070301; GO:0070588; GO:0071310; GO:0097604 1946 FUN_015878 0 9 0 4 0 NA NA NA NA NA NA NA 1947 FUN_015877 14 3 0 5 11 NA NA NA NA NA NA NA 1948 FUN_015874 22 0 23 0 16 NA NA NA NA NA NA NA 1949 FUN_015873 0 0 0 11 3 NA NA NA NA NA NA NA 1950 FUN_015872 40 64 29 13 19 NA NA NA NA NA NA NA 1951 FUN_015870 0 0 0 0 19 ptg000009l:17313897-17316480 P14381 1.07e-36 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 1952 FUN_015870 0 0 0 0 19 ptg000009l:17313897-17316480 P14381 1.07e-36 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 1953 FUN_015870 0 0 0 0 19 ptg000009l:17313897-17316480 P14381 1.07e-36 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 1954 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 1.9e-145 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1955 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 3.45e-140 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1956 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 4.15e-134 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1957 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 6.5e-132 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1958 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 3.53e-131 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1959 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 1.98e-119 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1960 FUN_026631 312 256 49 115 247 ptg000020l:11690924-11692385 A2VDQ7 1.19e-79 Zinc finger protein 420 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 1961 FUN_031488 191 78 8 766 74 NA NA NA NA NA NA NA 1962 FUN_020102 0 7 5 613 49 NA NA NA NA NA NA NA 1963 FUN_014588 4213 4568 2338 3199 3496 NA NA NA NA NA NA NA 1964 FUN_014589 3597 1762 1341 2765 1845 ptg000009l:1329937-1346316 Q2NKQ1 5.38e-21 Small G protein signaling modulator 1 (RUN and TBC1 domain-containing protein 2) Homo sapiens (Human) activation of GTPase activity [GO:0090630] GO:0005096; GO:0005737; GO:0005794; GO:0005829; GO:0030659; GO:0031267; GO:0090630 1965 FUN_023229 80 92 51 234 143 NA NA NA NA NA NA NA 1966 FUN_023228 2583 1890 1119 2672 2117 NA NA NA NA NA NA NA 1967 FUN_014584 5323 4194 2596 5414 5029 ptg000009l:1296326-1299065 Q8HXH0 2.07e-41 LON peptidase N-terminal domain and RING finger protein 3 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005737; GO:0046872 1968 FUN_014585 312 211 55 265 581 NA NA NA NA NA NA NA 1969 FUN_014586 1734 2113 1146 1669 301 NA NA NA NA NA NA NA 1970 FUN_014587 1455 1270 993 1325 654 ptg000009l:1319984-1322293 Q3SZ73 4.97e-27 Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) Bos taurus (Bovine) cellular lipid metabolic process [GO:0044255] GO:0005739; GO:0016787; GO:0044255 1971 FUN_014587 1455 1270 993 1325 654 ptg000009l:1319984-1322293 Q3SZ73 4.97e-27 Protein ABHD11 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 11) (Abhydrolase domain-containing protein 11) Bos taurus (Bovine) cellular lipid metabolic process [GO:0044255] GO:0005739; GO:0016787; GO:0044255 1972 FUN_014580 0 0 0 0 30 NA NA NA NA NA NA NA 1973 FUN_014581 81 9 64 27 221 NA NA NA NA NA NA NA 1974 FUN_023221 75 67 14 37 134 ptg000017l:5193425-5193767 O13023 4.32e-28 Hematopoietically-expressed homeobox protein hhex (Homeobox protein hex) (XHex) (Hhex-A protein) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; embryonic hemopoiesis [GO:0035162]; heart development [GO:0007507]; liver development [GO:0001889]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of Wnt signaling pathway [GO:0030177]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055] GO:0000122; GO:0000981; GO:0001570; GO:0001889; GO:0005634; GO:0007507; GO:0009952; GO:0016055; GO:0030177; GO:0035162; GO:0043565; GO:0045892 1975 FUN_023220 623 445 348 491 410 NA NA NA NA NA NA NA 1976 FUN_002436 30 0 18 0 0 NA NA NA NA NA NA NA 1977 FUN_010571 0 0 2 0 17 NA NA NA NA NA NA NA 1978 FUN_014051 0 0 0 0 35 NA NA NA NA NA NA NA 1979 FUN_014059 8 0 6 0 0 NA NA NA NA NA NA NA 1980 FUN_009461 621 2836 1195 1001 3913 NA NA NA NA NA NA NA 1981 FUN_009460 904 721 480 811 657 NA NA NA NA NA NA NA 1982 FUN_009463 52 90 0 21 39 NA NA NA NA NA NA NA 1983 FUN_009462 27 0 85 19 340 NA NA NA NA NA NA NA 1984 FUN_009465 50 0 82 26 222 NA NA NA NA NA NA NA 1985 FUN_009464 719 761 369 746 859 NA NA NA NA NA NA NA 1986 FUN_009467 18 0 26 134 100 NA NA NA NA NA NA NA 1987 FUN_009466 15 0 37 69 127 NA NA NA NA NA NA NA 1988 FUN_026479 312 47 53 251 66 ptg000020l:9408205-9409651 Q6DIV6 1.54e-63 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 1989 FUN_026478 4636 3445 2108 3522 2465 NA NA NA NA NA NA NA 1990 FUN_026471 1492 1895 1373 830 828 NA NA NA NA NA NA NA 1991 FUN_026470 297 292 299 453 554 NA NA NA NA NA NA NA 1992 FUN_026473 5427 1714 2240 1587 1125 NA NA NA NA NA NA NA 1993 FUN_026472 1271 756 606 1125 571 NA NA NA NA NA NA NA 1994 FUN_026475 1029 919 553 1479 1081 NA NA NA NA NA NA NA 1995 FUN_026474 2496 1856 2119 1233 862 NA NA NA NA NA NA NA 1996 FUN_026477 279 278 105 187 186 NA NA NA NA NA NA NA 1997 FUN_026476 496 440 310 638 548 NA NA NA NA NA NA NA 1998 FUN_041483 47 11 31 24 49 NA NA NA NA NA NA NA 1999 FUN_028160 54 534 1176 1744 250 NA NA NA NA NA NA NA 2000 FUN_041482 11 0 0 0 20 NA NA NA NA NA NA NA 2001 FUN_041481 2793 1814 1262 1875 1266 ptg000035l:4114997-4118723 P48430 5.51e-48 Transcription factor SOX-2 (cSox2) (delta EF2a) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; forebrain development [GO:0030900]; inner ear development [GO:0048839]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; sensory organ precursor cell fate determination [GO:0016360] GO:0000122; GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006355; GO:0009653; GO:0016360; GO:0030154; GO:0030900; GO:0043565; GO:0045165; GO:0045665; GO:0045893; GO:0045944; GO:0048839 2002 FUN_041480 1439 1353 744 1506 1543 NA NA NA NA NA NA NA 2003 FUN_022578 1805 1898 967 1785 1200 ptg000016l:10884710-10897485 Q9JLI7 5.4e-28 Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog) Mus musculus (Mouse) cell division [GO:0051301]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; ear development [GO:0043583]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of localization in cell [GO:0051649]; fibroblast migration [GO:0010761]; filopodium assembly [GO:0046847]; flagellated sperm motility [GO:0030317]; motile cilium assembly [GO:0044458]; mucociliary clearance [GO:0120197]; neuron projection extension [GO:1990138]; non-motile cilium assembly [GO:1905515]; protein localization [GO:0008104]; regulation of cilium beat frequency [GO:0003356]; regulation of establishment of planar polarity [GO:0090175]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283]; stress fiber assembly [GO:0043149]; substrate-dependent cell migration, cell attachment to substrate [GO:0006931]; ventricular system development [GO:0021591] GO:0001669; GO:0002177; GO:0003341; GO:0003351; GO:0003356; GO:0005576; GO:0005829; GO:0005874; GO:0005930; GO:0006931; GO:0007283; GO:0007288; GO:0008017; GO:0008104; GO:0010761; GO:0015630; GO:0021591; GO:0030317; GO:0031410; GO:0043149; GO:0043583; GO:0044458; GO:0045198; GO:0046847; GO:0051301; GO:0051649; GO:0090175; GO:0090660; GO:0097228; GO:0120197; GO:0120249; GO:1905515; GO:1990138; GO:1990716 2004 FUN_022578 1805 1898 967 1785 1200 ptg000016l:10884710-10897485 Q9JLI7 4.03e-21 Sperm-associated antigen 6 (Axoneme central apparatus protein) (Protein PF16 homolog) Mus musculus (Mouse) cell division [GO:0051301]; cerebrospinal fluid circulation [GO:0090660]; cilium movement [GO:0003341]; ear development [GO:0043583]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of localization in cell [GO:0051649]; fibroblast migration [GO:0010761]; filopodium assembly [GO:0046847]; flagellated sperm motility [GO:0030317]; motile cilium assembly [GO:0044458]; mucociliary clearance [GO:0120197]; neuron projection extension [GO:1990138]; non-motile cilium assembly [GO:1905515]; protein localization [GO:0008104]; regulation of cilium beat frequency [GO:0003356]; regulation of establishment of planar polarity [GO:0090175]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283]; stress fiber assembly [GO:0043149]; substrate-dependent cell migration, cell attachment to substrate [GO:0006931]; ventricular system development [GO:0021591] GO:0001669; GO:0002177; GO:0003341; GO:0003351; GO:0003356; GO:0005576; GO:0005829; GO:0005874; GO:0005930; GO:0006931; GO:0007283; GO:0007288; GO:0008017; GO:0008104; GO:0010761; GO:0015630; GO:0021591; GO:0030317; GO:0031410; GO:0043149; GO:0043583; GO:0044458; GO:0045198; GO:0046847; GO:0051301; GO:0051649; GO:0090175; GO:0090660; GO:0097228; GO:0120197; GO:0120249; GO:1905515; GO:1990138; GO:1990716 2005 FUN_022579 18 0 33 12 143 NA NA NA NA NA NA NA 2006 FUN_022574 108 129 149 294 113 ptg000016l:10830295-10836700 P78357 2.57e-26 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 2007 FUN_022575 61 341 224 555 131 ptg000016l:10846054-10873726 P78357 3.41e-26 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 2008 FUN_022575 61 341 224 555 131 ptg000016l:10846054-10873726 P78357 1.34e-25 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 2009 FUN_022575 61 341 224 555 131 ptg000016l:10846054-10873726 P78357 2.87e-25 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 2010 FUN_022575 61 341 224 555 131 ptg000016l:10846054-10873726 P78357 9.21e-22 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 2011 FUN_022576 6 144 181 158 87 NA NA NA NA NA NA NA 2012 FUN_022577 69 109 91 78 45 ptg000016l:10882110-10882617 Q94887 1.75e-30 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 2013 FUN_022570 14549 16297 7171 9617 6244 NA NA NA NA NA NA NA 2014 FUN_022572 180 185 146 216 133 ptg000016l:10808766-10823906 Q94887 2.07e-25 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 2015 FUN_022572 180 185 146 216 133 ptg000016l:10808766-10823906 Q94887 1.54e-22 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 2016 FUN_019181 0 7 0 0 0 NA NA NA NA NA NA NA 2017 FUN_019180 15 8 0 24 13 NA NA NA NA NA NA NA 2018 FUN_019188 0 0 0 0 15 NA NA NA NA NA NA NA 2019 FUN_041488 3964 2089 2558 2705 2290 ptg000035l:4252876-4258436 Q60803 2.27e-98 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 2020 FUN_018588 12 0 0 0 4 NA NA NA NA NA NA NA 2021 FUN_018589 13 0 0 9 4 NA NA NA NA NA NA NA 2022 FUN_018580 13 0 2 0 4 NA NA NA NA NA NA NA 2023 FUN_018581 13 0 3 5 5 NA NA NA NA NA NA NA 2024 FUN_018584 11 0 0 8 1 NA NA NA NA NA NA NA 2025 FUN_018587 0 0 0 6 4 NA NA NA NA NA NA NA 2026 FUN_021179 14 0 14 3 14 NA NA NA NA NA NA NA 2027 FUN_021178 0 0 0 10 0 NA NA NA NA NA NA NA 2028 FUN_021175 20 0 14 12 43 NA NA NA NA NA NA NA 2029 FUN_021174 0 38 0 0 0 NA NA NA NA NA NA NA 2030 FUN_021177 0 0 0 0 40 NA NA NA NA NA NA NA 2031 FUN_021171 0 0 0 0 77 NA NA NA NA NA NA NA 2032 FUN_021170 18 7 38 17 151 NA NA NA NA NA NA NA 2033 FUN_021172 0 0 0 0 172 NA NA NA NA NA NA NA 2034 FUN_017808 861 493 527 704 919 NA NA NA NA NA NA NA 2035 FUN_017804 64 34 14 50 31 ptg000012l:610154-611147 P51475 1.26e-45 Pinopsin (Pineal gland-specific opsin) (P-opsin) (Pineal opsin) Gallus gallus (Chicken) absorption of visible light [GO:0016038]; cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0001750; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016020; GO:0016038; GO:0036064; GO:0042599; GO:0071482; GO:0097232 2036 FUN_017805 26 0 0 8 8 ptg000012l:613235-615792 O13018 1.6e-43 Vertebrate ancient opsin Salmo salar (Atlantic salmon) phototransduction, visible light [GO:0007603] GO:0004930; GO:0007603; GO:0009881; GO:0016020 2037 FUN_017806 2507 1710 1543 2529 2890 NA NA NA NA NA NA NA 2038 FUN_017807 12554 15676 8402 13241 8053 ptg000012l:626733-648421 O60292 1.66e-21 Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cytoskeleton organization [GO:0007010]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell polarity [GO:0090162]; eye development [GO:0001654]; hematopoietic progenitor cell differentiation [GO:0002244]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0001654; GO:0001725; GO:0002244; GO:0003382; GO:0005096; GO:0005615; GO:0005654; GO:0005737; GO:0005794; GO:0005886; GO:0007010; GO:0016324; GO:0045177; GO:0051056; GO:0061689; GO:0090162; GO:0090630 2039 FUN_017800 348 200 217 313 222 NA NA NA NA NA NA NA 2040 FUN_017801 55 5 16 102 127 NA NA NA NA NA NA NA 2041 FUN_017802 433 177 289 340 292 NA NA NA NA NA NA NA 2042 FUN_017803 926 1015 828 1057 779 NA NA NA NA NA NA NA 2043 FUN_035372 11 14 15 8 67 NA NA NA NA NA NA NA 2044 FUN_035373 182 130 91 162 204 NA NA NA NA NA NA NA 2045 FUN_035370 16 31 0 27 33 NA NA NA NA NA NA NA 2046 FUN_035371 1013 795 391 1013 719 NA NA NA NA NA NA NA 2047 FUN_035376 477 498 181 265 109 NA NA NA NA NA NA NA 2048 FUN_035377 1947 2682 1759 3114 1455 NA NA NA NA NA NA NA 2049 FUN_035374 11 0 8 0 4 NA NA NA NA NA NA NA 2050 FUN_035375 3292 3160 2616 1255 802 NA NA NA NA NA NA NA 2051 FUN_035378 3474 4006 1011 3092 1839 NA NA NA NA NA NA NA 2052 FUN_035379 0 0 0 0 6 NA NA NA NA NA NA NA 2053 FUN_038393 749 444 306 930 591 NA NA NA NA NA NA NA 2054 FUN_038392 6642 2764 2425 4458 3300 NA NA NA NA NA NA NA 2055 FUN_038391 673 261 320 335 362 NA NA NA NA NA NA NA 2056 FUN_038390 557 311 355 520 399 NA NA NA NA NA NA NA 2057 FUN_038396 1385 922 816 1929 1941 ptg000027l:6748781-6749966 P63253 2.63e-87 Inward rectifier potassium channel 2 (Cardiac inward rectifier potassium channel) (Inward rectifier K(+) channel Kir2.1) (IRK-1) (Potassium channel, inwardly rectifying subfamily J member 2) Macaca mulatta (Rhesus macaque) cardiac muscle cell action potential involved in contraction [GO:0086002]; magnesium ion transport [GO:0015693]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane repolarization [GO:0060306]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076] GO:0005242; GO:0005546; GO:0005886; GO:0006813; GO:0008076; GO:0014861; GO:0015693; GO:0016020; GO:0034765; GO:0042802; GO:0051289; GO:0055119; GO:0060306; GO:0086002; GO:0086008; GO:0086091; GO:0090076; GO:1990573 2058 FUN_038395 2048 1378 938 2166 966 NA NA NA NA NA NA NA 2059 FUN_038394 3928 4300 2040 2622 2065 ptg000027l:6733147-6738613 Q9HCN4 6.03e-34 GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1) Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005654; GO:0005739; GO:0005829 2060 FUN_038394 3928 4300 2040 2622 2065 ptg000027l:6733147-6738613 Q9HCN4 6.8e-33 GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1) Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005654; GO:0005739; GO:0005829 2061 FUN_038394 3928 4300 2040 2622 2065 ptg000027l:6733147-6738613 Q9HCN4 1.99e-24 GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1) Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005654; GO:0005739; GO:0005829 2062 FUN_038398 1308 1563 1861 1916 1490 ptg000027l:6758475-6759771 Q4TZY1 4.22e-108 ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) Bos taurus (Bovine) potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0006813; GO:0016020; GO:0034765; GO:0051289; GO:1990573 2063 FUN_031870 3174 2063 1863 2738 2098 NA NA NA NA NA NA NA 2064 FUN_031873 39 29 47 15 44 NA NA NA NA NA NA NA 2065 FUN_031872 0 0 47 13 33 ptg000023l:26264821-26267284 P0A651 6.81e-22 Putative diacyglycerol O-acyltransferase Mb3154c (EC 2.3.1.20) (Putative triacylglycerol synthase Mb3154c) Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0006071; GO:0019432 2066 FUN_031875 12739 18116 7432 9629 9660 ptg000023l:26292184-26311848 Q8BVW0 7.83e-24 Neutral alpha-glucosidase C (EC 3.2.1.20) Mus musculus (Mouse) glucose metabolic process [GO:0006006]; N-glycan processing [GO:0006491] GO:0004553; GO:0004558; GO:0006006; GO:0006491; GO:0030246; GO:0032450; GO:0090599 2067 FUN_031874 6120 3902 2494 4514 2781 NA NA NA NA NA NA NA 2068 FUN_031877 1729 1281 818 1293 942 ptg000023l:26321283-26336502 O08529 9.3e-29 Calpain-2 catalytic subunit (EC 3.4.22.53) (80 kDa M-calpain subunit) (CALP80) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain) Mus musculus (Mouse) behavioral response to pain [GO:0048266]; blastocyst development [GO:0001824]; cellular response to amino acid stimulus [GO:0071230]; cellular response to interferon-beta [GO:0035458]; cellular response to lipopolysaccharide [GO:0071222]; female pregnancy [GO:0007565]; myoblast fusion [GO:0007520]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neuron death [GO:1901216]; positive regulation of phosphatidylcholine biosynthetic process [GO:2001247]; protein autoprocessing [GO:0016540]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of interleukin-6 production [GO:0032675]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to mechanical stimulus [GO:0009612] GO:0000785; GO:0001666; GO:0001824; GO:0004198; GO:0005509; GO:0005634; GO:0005737; GO:0005758; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0005925; GO:0006508; GO:0007520; GO:0007565; GO:0008092; GO:0008233; GO:0009612; GO:0009897; GO:0010666; GO:0016020; GO:0016540; GO:0019899; GO:0030163; GO:0030425; GO:0031143; GO:0032675; GO:0035458; GO:0042542; GO:0042995; GO:0043025; GO:0044877; GO:0045121; GO:0048266; GO:0051603; GO:0071222; GO:0071230; GO:0097038; GO:0110158; GO:1901216; GO:1901741; GO:2001247 2069 FUN_031876 4644 3949 1813 3401 2136 ptg000023l:26312052-26319766 P63100 4.42e-29 Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1) Rattus norvegicus (Rat) branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of synaptic vesicle cycle [GO:0098693]; Schwann cell development [GO:0014044] GO:0001569; GO:0001837; GO:0004721; GO:0005509; GO:0005829; GO:0005955; GO:0006470; GO:0006606; GO:0007507; GO:0008597; GO:0014044; GO:0016018; GO:0019899; GO:0019902; GO:0019904; GO:0022011; GO:0033173; GO:0034504; GO:0042383; GO:0045202; GO:0045944; GO:0060487; GO:0097720; GO:0098685; GO:0098686; GO:0098688; GO:0098693; GO:0098794; GO:0098978; GO:0099149; GO:0099170 2070 FUN_031876 4644 3949 1813 3401 2136 ptg000023l:26312052-26319766 P63100 5.39e-27 Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1) Rattus norvegicus (Rat) branching involved in blood vessel morphogenesis [GO:0001569]; calcineurin-mediated signaling [GO:0097720]; calcineurin-NFAT signaling cascade [GO:0033173]; epithelial to mesenchymal transition [GO:0001837]; heart development [GO:0007507]; lung epithelial cell differentiation [GO:0060487]; myelination in peripheral nervous system [GO:0022011]; positive regulation of transcription by RNA polymerase II [GO:0045944]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; protein dephosphorylation [GO:0006470]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of synaptic vesicle cycle [GO:0098693]; Schwann cell development [GO:0014044] GO:0001569; GO:0001837; GO:0004721; GO:0005509; GO:0005829; GO:0005955; GO:0006470; GO:0006606; GO:0007507; GO:0008597; GO:0014044; GO:0016018; GO:0019899; GO:0019902; GO:0019904; GO:0022011; GO:0033173; GO:0034504; GO:0042383; GO:0045202; GO:0045944; GO:0060487; GO:0097720; GO:0098685; GO:0098686; GO:0098688; GO:0098693; GO:0098794; GO:0098978; GO:0099149; GO:0099170 2071 FUN_031878 387 384 294 920 544 ptg000023l:26384841-26409082 Q9W0Y8 2.38e-69 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 2072 FUN_031878 387 384 294 920 544 ptg000023l:26384841-26409082 Q9W0Y8 2.95e-33 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 2073 FUN_031878 387 384 294 920 544 ptg000023l:26384841-26409082 Q9W0Y8 6.05e-23 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 2074 FUN_014734 4460 4387 1647 3087 1115 NA NA NA NA NA NA NA 2075 FUN_030476 9 0 9 1 41 ptg000023l:10958553-10959316 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2076 FUN_030472 3 0 3 0 8 ptg000023l:10949792-10953472 P35061 7.86e-76 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2077 FUN_030473 4 1 2 0 11 NA NA NA NA NA NA NA 2078 FUN_030470 8 0 9 0 34 ptg000023l:10943216-10943979 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2079 FUN_030471 13 1 5 2 78 ptg000023l:10944243-10944555 Q6LAF1 1.14e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2080 FUN_021791 5 0 0 16 202 NA NA NA NA NA NA NA 2081 FUN_021793 12 0 0 0 45 NA NA NA NA NA NA NA 2082 FUN_021795 0 0 0 0 21 NA NA NA NA NA NA NA 2083 FUN_038645 244 291 60 297 340 NA NA NA NA NA NA NA 2084 FUN_004966 43 0 0 0 40 NA NA NA NA NA NA NA 2085 FUN_004964 0 0 0 11 4 NA NA NA NA NA NA NA 2086 FUN_004963 0 10 0 1 0 NA NA NA NA NA NA NA 2087 FUN_004962 0 0 0 9 0 NA NA NA NA NA NA NA 2088 FUN_038643 259 125 55 97 192 ptg000027l:9706150-9730252 Q5RCY5 1.59e-23 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 2089 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2090 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 5.88e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2091 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 3.1e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2092 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 2e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2093 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 9.17e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2094 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 2.26e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2095 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 2.26e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2096 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 1.11e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2097 FUN_038642 114 42 5 16 33 ptg000027l:9685036-9691812 Q96AY4 6.89e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2098 FUN_038649 0 21 0 0 29 NA NA NA NA NA NA NA 2099 FUN_038648 0 0 0 0 13 ptg000027l:9776741-9778672 Q1LYL8 5.48e-30 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 2100 FUN_038648 0 0 0 0 13 ptg000027l:9776741-9778672 Q1LYL8 5.48e-30 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 2101 FUN_004969 78 7 196 409 39 NA NA NA NA NA NA NA 2102 FUN_004968 2 0 3 0 25 NA NA NA NA NA NA NA 2103 FUN_043167 0 0 0 6 0 NA NA NA NA NA NA NA 2104 FUN_011444 5 0 15 1 49 NA NA NA NA NA NA NA 2105 FUN_043165 0 14 0 0 0 NA NA NA NA NA NA NA 2106 FUN_011442 3 0 9 2 31 NA NA NA NA NA NA NA 2107 FUN_014732 0 235 137 0 0 NA NA NA NA NA NA NA 2108 FUN_011443 10 3 32 14 24 NA NA NA NA NA NA NA 2109 FUN_011440 17 0 0 0 0 NA NA NA NA NA NA NA 2110 FUN_043161 1603 860 936 1402 1089 NA NA NA NA NA NA NA 2111 FUN_000942 1413 950 735 1282 928 ntLink_6:6326654-6329135 Q03601 9.89e-40 RING finger protein nhl-1 Caenorhabditis elegans negative regulation of translation [GO:0017148]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0004842; GO:0016567; GO:0017148; GO:0030371; GO:0043161; GO:0046872; GO:0061630 2112 FUN_000946 2284 1649 991 1800 887 NA NA NA NA NA NA NA 2113 FUN_036135 0 34 27 32 26 ptg000025l:15657612-15660579 P35061 2.71e-54 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2114 FUN_036130 248 290 82 133 0 NA NA NA NA NA NA NA 2115 FUN_036133 36 0 0 40 30 ptg000025l:15646094-15649547 Q6PC60 9.22e-53 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 2116 FUN_039113 0 0 0 0 8 NA NA NA NA NA NA NA 2117 FUN_036139 0 0 14 0 0 ptg000025l:15668889-15669552 P35061 7.26e-65 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2118 FUN_039115 57 0 42 0 162 ptg000027l:14749539-14753510 Q6LAF1 8.64e-47 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2119 FUN_023083 209 21 78 120 39 ptg000017l:3434192-3435365 O43603 8.74e-24 Galanin receptor type 2 (GAL2-R) (GALR-2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell surface receptor signaling pathway [GO:0007166]; feeding behavior [GO:0007631]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; learning or memory [GO:0007611]; muscle contraction [GO:0006936]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0006936; GO:0007166; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0007611; GO:0007631; GO:0008528; GO:0016020; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 2120 FUN_037849 1403 599 804 1072 870 NA NA NA NA NA NA NA 2121 FUN_037846 1780 506 2026 2494 1416 NA NA NA NA NA NA NA 2122 FUN_037847 1791 1030 843 1480 3792 NA NA NA NA NA NA NA 2123 FUN_037844 34 37 29 80 13 NA NA NA NA NA NA NA 2124 FUN_037845 6798 4349 3355 4951 3455 NA NA NA NA NA NA NA 2125 FUN_037842 621 140 196 411 338 NA NA NA NA NA NA NA 2126 FUN_037843 3834 3145 1801 3959 3447 NA NA NA NA NA NA NA 2127 FUN_037840 6435 3205 2249 5589 4506 NA NA NA NA NA NA NA 2128 FUN_037841 154 125 132 286 109 NA NA NA NA NA NA NA 2129 FUN_006993 1120 629 481 1035 787 NA NA NA NA NA NA NA 2130 FUN_027797 20 0 10 32 0 NA NA NA NA NA NA NA 2131 FUN_027796 20 0 0 3 0 NA NA NA NA NA NA NA 2132 FUN_027795 19 25 0 0 23 NA NA NA NA NA NA NA 2133 FUN_027799 43 0 13 0 29 NA NA NA NA NA NA NA 2134 FUN_027798 0 0 12 0 0 NA NA NA NA NA NA NA 2135 FUN_014784 88 157 48 504 247 NA NA NA NA NA NA NA 2136 FUN_006995 1918 1816 1366 1859 2238 NA NA NA NA NA NA NA 2137 FUN_014785 82 17 3 81 117 NA NA NA NA NA NA NA 2138 FUN_014782 90 60 114 184 167 NA NA NA NA NA NA NA 2139 FUN_019012 0 0 0 0 16 NA NA NA NA NA NA NA 2140 FUN_014781 7001 5992 9819 7444 8750 NA NA NA NA NA NA NA 2141 FUN_027245 274 20 231 301 51 NA NA NA NA NA NA NA 2142 FUN_027244 306 250 201 372 108 NA NA NA NA NA NA NA 2143 FUN_027246 125 85 148 77 41 NA NA NA NA NA NA NA 2144 FUN_027241 780 203 253 604 142 ptg000021l:2162366-2171816 P59046 4.84e-39 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 2145 FUN_027241 780 203 253 604 142 ptg000021l:2162366-2171816 P59046 9.16e-21 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 2146 FUN_027240 0 0 13 7 3 NA NA NA NA NA NA NA 2147 FUN_027243 0 0 7 7 8 NA NA NA NA NA NA NA 2148 FUN_027242 1018 427 567 1196 659 ptg000021l:2172983-2179694 Q7RTR2 5.61e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2149 FUN_027242 1018 427 567 1196 659 ptg000021l:2172983-2179694 Q7RTR2 9.43e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2150 FUN_037268 0 0 0 0 27 NA NA NA NA NA NA NA 2151 FUN_037265 0 27 0 0 0 NA NA NA NA NA NA NA 2152 FUN_028185 3683 2583 1915 4357 3097 NA NA NA NA NA NA NA 2153 FUN_005368 173 67 38 128 24 NA NA NA NA NA NA NA 2154 FUN_005369 2925 2116 1627 2048 2411 NA NA NA NA NA NA NA 2155 FUN_005366 15291 15565 8409 11763 12304 NA NA NA NA NA NA NA 2156 FUN_005367 564 285 282 519 149 NA NA NA NA NA NA NA 2157 FUN_005364 0 0 0 6 0 NA NA NA NA NA NA NA 2158 FUN_005365 49636 49679 22449 44329 38500 ntLink_8:34419191-34421202 O01727 1.93e-64 40S ribosomal protein S6 Branchiostoma floridae (Florida lancelet) (Amphioxus) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 2159 FUN_005362 36 20 18 0 246 NA NA NA NA NA NA NA 2160 FUN_005363 133 69 56 101 114 ntLink_8:34411198-34413139 Q7L5Y6 0 DET1 homolog (De-etiolated-1 homolog) Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003] GO:0005634; GO:0016567; GO:0031461; GO:0031464; GO:0031625; GO:0032436; GO:0044877; GO:0065003; GO:0080008; GO:1990756 2161 FUN_005363 133 69 56 101 114 ntLink_8:34411198-34413139 Q7L5Y6 8.61e-22 DET1 homolog (De-etiolated-1 homolog) Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003] GO:0005634; GO:0016567; GO:0031461; GO:0031464; GO:0031625; GO:0032436; GO:0044877; GO:0065003; GO:0080008; GO:1990756 2162 FUN_005361 2 0 0 0 9 NA NA NA NA NA NA NA 2163 FUN_003401 0 14 0 9 28 NA NA NA NA NA NA NA 2164 FUN_003400 27 0 50 0 139 NA NA NA NA NA NA NA 2165 FUN_003403 7 0 0 0 0 NA NA NA NA NA NA NA 2166 FUN_022017 1536 1161 859 1202 1641 NA NA NA NA NA NA NA 2167 FUN_025044 11 0 0 12 0 NA NA NA NA NA NA NA 2168 FUN_025047 10 0 0 0 0 NA NA NA NA NA NA NA 2169 FUN_022014 218 53 0 45 3 NA NA NA NA NA NA NA 2170 FUN_006479 0 582 0 40 910 NA NA NA NA NA NA NA 2171 FUN_006478 363 351 368 691 343 NA NA NA NA NA NA NA 2172 FUN_006477 246 85 69 329 128 NA NA NA NA NA NA NA 2173 FUN_006476 109 487 251 744 754 NA NA NA NA NA NA NA 2174 FUN_006475 0 0 0 0 9 NA NA NA NA NA NA NA 2175 FUN_006474 27 0 0 0 165 NA NA NA NA NA NA NA 2176 FUN_006473 492 805 722 312 765 NA NA NA NA NA NA NA 2177 FUN_006472 265 465 128 430 513 NA NA NA NA NA NA NA 2178 FUN_006471 0 6 0 212 5 NA NA NA NA NA NA NA 2179 FUN_032725 10 0 20 7 25 NA NA NA NA NA NA NA 2180 FUN_032726 27 0 20 0 12 NA NA NA NA NA NA NA 2181 FUN_032728 35 0 151 71 83 NA NA NA NA NA NA NA 2182 FUN_004181 0 0 0 0 32 NA NA NA NA NA NA NA 2183 FUN_004180 40 23 57 5 33 NA NA NA NA NA NA NA 2184 FUN_004183 364 454 236 675 721 NA NA NA NA NA NA NA 2185 FUN_004182 0 0 10 0 1 NA NA NA NA NA NA NA 2186 FUN_004184 0 54 0 117 0 NA NA NA NA NA NA NA 2187 FUN_004187 0 76 62 60 31 NA NA NA NA NA NA NA 2188 FUN_004186 123 121 59 129 5 NA NA NA NA NA NA NA 2189 FUN_004189 9 53 13 10 32 NA NA NA NA NA NA NA 2190 FUN_004188 25 57 65 39 21 NA NA NA NA NA NA NA 2191 FUN_034768 2 2 2 0 10 NA NA NA NA NA NA NA 2192 FUN_034769 77 239 109 218 538 NA NA NA NA NA NA NA 2193 FUN_034765 0 0 0 0 6 NA NA NA NA NA NA NA 2194 FUN_034760 0 0 0 0 12 NA NA NA NA NA NA NA 2195 FUN_001298 1032 700 482 1407 929 NA NA NA NA NA NA NA 2196 FUN_001299 874 384 471 845 1779 NA NA NA NA NA NA NA 2197 FUN_001292 67 65 73 109 83 NA NA NA NA NA NA NA 2198 FUN_001290 2361 2133 1240 2705 1947 NA NA NA NA NA NA NA 2199 FUN_001291 14 120 41 116 58 NA NA NA NA NA NA NA 2200 FUN_001296 260 80 58 63 83 NA NA NA NA NA NA NA 2201 FUN_001297 11 0 0 0 21 NA NA NA NA NA NA NA 2202 FUN_001294 29 10 55 23 46 NA NA NA NA NA NA NA 2203 FUN_001295 11 29 0 0 0 ntLink_6:10870339-10872205 A0JPI9 6.76e-48 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 2204 FUN_007989 18841 12806 8682 10382 10041 NA NA NA NA NA NA NA 2205 FUN_007984 0 239 30 137 59 NA NA NA NA NA NA NA 2206 FUN_007986 15 5 3 6 16 NA NA NA NA NA NA NA 2207 FUN_007980 1769 1985 826 1130 1074 NA NA NA NA NA NA NA 2208 FUN_007981 843 301 287 596 272 NA NA NA NA NA NA NA 2209 FUN_007982 16 0 0 0 0 NA NA NA NA NA NA NA 2210 FUN_007983 3432 2564 1074 1909 1453 NA NA NA NA NA NA NA 2211 FUN_038126 617 203 426 562 283 NA NA NA NA NA NA NA 2212 FUN_001128 2271 107 165 419 92 NA NA NA NA NA NA NA 2213 FUN_001129 14 0 32 5 3 NA NA NA NA NA NA NA 2214 FUN_030341 6 0 9 0 29 ptg000023l:10644994-10645757 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2215 FUN_001124 72 47 947 1604 182 NA NA NA NA NA NA NA 2216 FUN_001125 49 112 46 76 22 NA NA NA NA NA NA NA 2217 FUN_001126 6946 286 760 8415 70 NA NA NA NA NA NA NA 2218 FUN_001127 0 0 0 1374 10 NA NA NA NA NA NA NA 2219 FUN_001120 94 124 85 179 139 NA NA NA NA NA NA NA 2220 FUN_001121 160 137 182 131 243 ntLink_6:8811184-8822911 Q96P65 2.61e-26 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 2221 FUN_001122 199 200 227 221 236 ntLink_6:8824474-8839600 Q5XG71 1.06e-23 Small subunit processome component 20 homolog (Down-regulated in metastasis protein) Mus musculus (Mouse) rRNA processing [GO:0006364] GO:0005730; GO:0005886; GO:0006364; GO:0030686; GO:0032040 2222 FUN_001123 14 33 433 998 120 NA NA NA NA NA NA NA 2223 FUN_026501 1594 476 708 1808 896 NA NA NA NA NA NA NA 2224 FUN_034188 108 100 176 148 364 NA NA NA NA NA NA NA 2225 FUN_034189 2817 1198 927 2229 2680 NA NA NA NA NA NA NA 2226 FUN_026500 0 0 4 0 7 NA NA NA NA NA NA NA 2227 FUN_034182 366 474 156 229 324 NA NA NA NA NA NA NA 2228 FUN_034180 552 325 120 221 454 NA NA NA NA NA NA NA 2229 FUN_034181 114 37 18 42 52 NA NA NA NA NA NA NA 2230 FUN_026503 1395 54 744 1248 1362 NA NA NA NA NA NA NA 2231 FUN_011770 1536 1255 1099 2289 2179 ptg000008l:1194342-1205245 O35889 5.31e-77 Afadin (Afadin adherens junction formation factor) (Protein Af-6) Rattus norvegicus (Rat) adherens junction maintenance [GO:0034334]; bicellular tight junction assembly [GO:0070830]; brain morphogenesis [GO:0048854]; cell-cell adhesion mediated by cadherin [GO:0044331]; cerebral cortex development [GO:0021987]; dendrite arborization [GO:0140059]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; homeostasis of number of cells [GO:0048872]; negative regulation of cell migration [GO:0030336]; neuroepithelial cell differentiation [GO:0060563]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; protein localization to cell junction [GO:1902414]; radial glial cell differentiation [GO:0060019]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]; telencephalon development [GO:0021537] GO:0005737; GO:0005829; GO:0005911; GO:0005912; GO:0007165; GO:0010628; GO:0021537; GO:0021987; GO:0022409; GO:0030054; GO:0030274; GO:0030336; GO:0030424; GO:0031267; GO:0032880; GO:0034334; GO:0036477; GO:0043296; GO:0043547; GO:0044291; GO:0044331; GO:0045177; GO:0046930; GO:0046931; GO:0048854; GO:0048872; GO:0050775; GO:0050839; GO:0051015; GO:0060019; GO:0060563; GO:0061003; GO:0061885; GO:0061951; GO:0070160; GO:0070445; GO:0070830; GO:0090557; GO:0140059; GO:1902414; GO:1903861; GO:2000049 2232 FUN_011770 1536 1255 1099 2289 2179 ptg000008l:1194342-1205245 O35889 4.47e-33 Afadin (Afadin adherens junction formation factor) (Protein Af-6) Rattus norvegicus (Rat) adherens junction maintenance [GO:0034334]; bicellular tight junction assembly [GO:0070830]; brain morphogenesis [GO:0048854]; cell-cell adhesion mediated by cadherin [GO:0044331]; cerebral cortex development [GO:0021987]; dendrite arborization [GO:0140059]; establishment of endothelial intestinal barrier [GO:0090557]; establishment of protein localization to plasma membrane [GO:0061951]; homeostasis of number of cells [GO:0048872]; negative regulation of cell migration [GO:0030336]; neuroepithelial cell differentiation [GO:0060563]; pore complex assembly [GO:0046931]; positive regulation of cell-cell adhesion [GO:0022409]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of dendrite extension [GO:1903861]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of gene expression [GO:0010628]; positive regulation of GTPase activity [GO:0043547]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; protein localization to cell junction [GO:1902414]; radial glial cell differentiation [GO:0060019]; regulation of oligodendrocyte progenitor proliferation [GO:0070445]; regulation of protein localization [GO:0032880]; signal transduction [GO:0007165]; telencephalon development [GO:0021537] GO:0005737; GO:0005829; GO:0005911; GO:0005912; GO:0007165; GO:0010628; GO:0021537; GO:0021987; GO:0022409; GO:0030054; GO:0030274; GO:0030336; GO:0030424; GO:0031267; GO:0032880; GO:0034334; GO:0036477; GO:0043296; GO:0043547; GO:0044291; GO:0044331; GO:0045177; GO:0046930; GO:0046931; GO:0048854; GO:0048872; GO:0050775; GO:0050839; GO:0051015; GO:0060019; GO:0060563; GO:0061003; GO:0061885; GO:0061951; GO:0070160; GO:0070445; GO:0070830; GO:0090557; GO:0140059; GO:1902414; GO:1903861; GO:2000049 2233 FUN_011771 3693 2938 2073 3538 4235 NA NA NA NA NA NA NA 2234 FUN_011772 418 321 135 411 544 NA NA NA NA NA NA NA 2235 FUN_011774 1160 644 734 1003 1118 NA NA NA NA NA NA NA 2236 FUN_011775 266 179 186 253 217 ptg000008l:1243202-1262538 P29145 1.96e-27 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 2237 FUN_011776 26538 17387 9164 27493 11821 ptg000008l:1281430-1288880 Q03347 3.47e-50 Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit) Mus musculus (Mouse) behavioral response to pain [GO:0048266]; cellular response to transforming growth factor beta stimulus [GO:0071560]; central nervous system development [GO:0007417]; chondrocyte differentiation [GO:0002062]; definitive hemopoiesis [GO:0060216]; embryonic hemopoiesis [GO:0035162]; hair follicle morphogenesis [GO:0031069]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; myeloid cell differentiation [GO:0030099]; myeloid leukocyte differentiation [GO:0002573]; myeloid progenitor cell differentiation [GO:0002318]; negative regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043371]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of granulocyte differentiation [GO:0030853]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; ossification [GO:0001503]; positive regulation of angiogenesis [GO:0045766]; positive regulation of CD8-positive, alpha-beta T cell differentiation [GO:0043378]; positive regulation of cell maturation [GO:1903431]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of progesterone secretion [GO:2000872]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle cell proliferation [GO:0071336]; regulation of signal transduction [GO:0009966]; regulation of T cell anergy [GO:0002667]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; skeletal system development [GO:0001501] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001222; GO:0001223; GO:0001228; GO:0001501; GO:0001503; GO:0001701; GO:0001889; GO:0002062; GO:0002318; GO:0002573; GO:0002667; GO:0003677; GO:0003700; GO:0005509; GO:0005524; GO:0005604; GO:0005634; GO:0005654; GO:0006355; GO:0006357; GO:0007417; GO:0008285; GO:0009966; GO:0016513; GO:0030097; GO:0030099; GO:0030182; GO:0030853; GO:0030854; GO:0031069; GO:0032526; GO:0032729; GO:0032743; GO:0032991; GO:0035162; GO:0042803; GO:0043231; GO:0043371; GO:0043378; GO:0045595; GO:0045766; GO:0045892; GO:0045893; GO:0045944; GO:0046982; GO:0048266; GO:0048663; GO:0048666; GO:0060216; GO:0071336; GO:0071560; GO:0140297; GO:1903431; GO:1990837; GO:1990841; GO:2000872 2238 FUN_011777 1775 1307 949 2052 1536 NA NA NA NA NA NA NA 2239 FUN_011778 2172 2152 1304 1793 1175 NA NA NA NA NA NA NA 2240 FUN_026505 0 0 0 0 11 NA NA NA NA NA NA NA 2241 FUN_035191 788 252 308 540 672 NA NA NA NA NA NA NA 2242 FUN_000457 0 0 0 6 23 NA NA NA NA NA NA NA 2243 FUN_000456 36 5 4 22 52 NA NA NA NA NA NA NA 2244 FUN_000455 620 323 215 335 686 NA NA NA NA NA NA NA 2245 FUN_000454 350 549 1033 2538 902 NA NA NA NA NA NA NA 2246 FUN_000989 8074 5270 2645 3495 1666 NA NA NA NA NA NA NA 2247 FUN_000988 7687 5045 3304 5994 3976 ntLink_6:6929033-6938599 A8WGE3 9.65e-40 Coronin-2B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003779; GO:0005737; GO:0005856 2248 FUN_000988 7687 5045 3304 5994 3976 ntLink_6:6929033-6938599 A8WGE3 3.25e-21 Coronin-2B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003779; GO:0005737; GO:0005856 2249 FUN_029308 8569 4849 4549 8189 8547 NA NA NA NA NA NA NA 2250 FUN_029309 4688 2825 2177 3565 3712 NA NA NA NA NA NA NA 2251 FUN_029306 6291 4618 3484 6847 4348 ptg000023l:291321-315808 O55164 1.36e-31 Multiple PDZ domain protein (Multi-PDZ domain protein 1) Rattus norvegicus (Rat) cell adhesion [GO:0007155]; dendrite development [GO:0016358]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; myelination [GO:0042552] GO:0005737; GO:0005923; GO:0006886; GO:0007155; GO:0008022; GO:0012505; GO:0014069; GO:0016324; GO:0016327; GO:0016358; GO:0030425; GO:0031410; GO:0035003; GO:0035556; GO:0042552; GO:0043220; GO:0045202; GO:0098978 2252 FUN_000984 446 183 121 124 143 NA NA NA NA NA NA NA 2253 FUN_029304 0 14 0 0 0 NA NA NA NA NA NA NA 2254 FUN_029305 898 643 683 1263 741 ptg000023l:287893-289045 P49288 5.15e-25 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 2255 FUN_000981 20 17 48 32 75 NA NA NA NA NA NA NA 2256 FUN_000980 4911 4736 2880 7640 5407 NA NA NA NA NA NA NA 2257 FUN_029301 531 392 218 490 1052 NA NA NA NA NA NA NA 2258 FUN_012511 67 6 50 22 27 NA NA NA NA NA NA NA 2259 FUN_012510 3459 70 1653 1869 1433 NA NA NA NA NA NA NA 2260 FUN_012513 3497 891 1435 1257 1185 NA NA NA NA NA NA NA 2261 FUN_012512 4032 130 2256 1927 1971 NA NA NA NA NA NA NA 2262 FUN_012515 214 127 148 246 179 NA NA NA NA NA NA NA 2263 FUN_012514 1178 562 449 700 281 NA NA NA NA NA NA NA 2264 FUN_012517 526 395 212 606 403 NA NA NA NA NA NA NA 2265 FUN_012516 1341 779 475 787 432 NA NA NA NA NA NA NA 2266 FUN_012519 1 11 4 2 4 NA NA NA NA NA NA NA 2267 FUN_012518 595 556 438 525 590 ptg000008l:9563700-9570080 O54862 2.12e-23 Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) bone maturation [GO:0070977]; cholesterol metabolic process [GO:0008203]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; response to endoplasmic reticulum stress [GO:0034976] GO:0004222; GO:0005737; GO:0008203; GO:0016020; GO:0031293; GO:0034976; GO:0046872; GO:0051091; GO:0070977; GO:1990440 2268 FUN_012518 595 556 438 525 590 ptg000008l:9563700-9570080 O54862 2.12e-23 Membrane-bound transcription factor site-2 protease (EC 3.4.24.85) (Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) bone maturation [GO:0070977]; cholesterol metabolic process [GO:0008203]; membrane protein intracellular domain proteolysis [GO:0031293]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990440]; response to endoplasmic reticulum stress [GO:0034976] GO:0004222; GO:0005737; GO:0008203; GO:0016020; GO:0031293; GO:0034976; GO:0046872; GO:0051091; GO:0070977; GO:1990440 2269 FUN_003188 0 0 0 2 28 NA NA NA NA NA NA NA 2270 FUN_016200 987 62 225 359 541 ptg000011l:259505-261444 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2271 FUN_016200 987 62 225 359 541 ptg000011l:259505-261444 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2272 FUN_016200 987 62 225 359 541 ptg000011l:259505-261444 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2273 FUN_016200 987 62 225 359 541 ptg000011l:259505-261444 Q5R5U3 1.09e-150 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2274 FUN_016200 987 62 225 359 541 ptg000011l:259505-261444 Q5R5U3 1.16e-88 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2275 FUN_016200 987 62 225 359 541 ptg000011l:259505-261444 Q5R5U3 1.64e-72 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2276 FUN_016203 1204 216 652 3312 3094 NA NA NA NA NA NA NA 2277 FUN_016202 1598 615 643 1702 2070 ptg000011l:268342-311694 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2278 FUN_016202 1598 615 643 1702 2070 ptg000011l:268342-311694 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2279 FUN_016202 1598 615 643 1702 2070 ptg000011l:268342-311694 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2280 FUN_016202 1598 615 643 1702 2070 ptg000011l:268342-311694 Q5R5U3 2.06e-106 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 2281 FUN_016205 0 0 0 0 16 ptg000011l:350097-353461 P36898 3.7e-79 Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (Activin receptor-like kinase 6) (ALK-6) (Serine/threonine-protein kinase receptor R6) (SKR6) (CD antigen CDw293) Mus musculus (Mouse) BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; camera-type eye development [GO:0043010]; cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; central nervous system neuron differentiation [GO:0021953]; chondrocyte development [GO:0002063]; chondrocyte differentiation [GO:0002062]; dorsal/ventral pattern formation [GO:0009953]; endochondral bone morphogenesis [GO:0060350]; estrogen biosynthetic process [GO:0006703]; eye development [GO:0001654]; inflammatory response [GO:0006954]; negative regulation of chondrocyte proliferation [GO:1902731]; osteoblast differentiation [GO:0001649]; ovarian cumulus expansion [GO:0001550]; ovulation cycle [GO:0042698]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; retina development in camera-type eye [GO:0060041]; retinal ganglion cell axon guidance [GO:0031290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] GO:0001502; GO:0001550; GO:0001649; GO:0001654; GO:0002062; GO:0002063; GO:0004674; GO:0004675; GO:0005024; GO:0005025; GO:0005524; GO:0005886; GO:0006468; GO:0006703; GO:0006954; GO:0007178; GO:0007179; GO:0009953; GO:0010628; GO:0019211; GO:0021953; GO:0030154; GO:0030166; GO:0030425; GO:0030501; GO:0030509; GO:0031290; GO:0032332; GO:0036122; GO:0042698; GO:0043010; GO:0043025; GO:0043235; GO:0043539; GO:0045669; GO:0045944; GO:0046332; GO:0046872; GO:0060041; GO:0060348; GO:0060350; GO:0061036; GO:0071363; GO:0071773; GO:0098821; GO:0140537; GO:1902043; GO:1902731 2282 FUN_016204 929 27 538 3054 2615 NA NA NA NA NA NA NA 2283 FUN_016207 0 0 0 10 21 NA NA NA NA NA NA NA 2284 FUN_016206 0 128 0 171 0 NA NA NA NA NA NA NA 2285 FUN_016209 0 0 0 0 68 NA NA NA NA NA NA NA 2286 FUN_016208 360 110 252 666 368 NA NA NA NA NA NA NA 2287 FUN_003184 14 0 9 0 62 NA NA NA NA NA NA NA 2288 FUN_003185 0 0 2 1 56 NA NA NA NA NA NA NA 2289 FUN_003186 50 0 64 4 315 ntLink_8:8499473-8501247 Q9U7D0 3.61e-47 Histone H4 Mastigamoeba balamuthi (Phreatamoeba balamuthi) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2290 FUN_003187 13 0 16 0 123 NA NA NA NA NA NA NA 2291 FUN_026849 1389 279 231 1135 211 NA NA NA NA NA NA NA 2292 FUN_043746 14 0 0 0 4 NA NA NA NA NA NA NA 2293 FUN_043747 40 2 30 49 15 NA NA NA NA NA NA NA 2294 FUN_043744 0 0 0 14 0 NA NA NA NA NA NA NA 2295 FUN_043743 0 0 6 0 0 NA NA NA NA NA NA NA 2296 FUN_043749 6 0 27 0 0 NA NA NA NA NA NA NA 2297 FUN_042299 4 2 26 2 9 NA NA NA NA NA NA NA 2298 FUN_042298 0 0 5 0 10 NA NA NA NA NA NA NA 2299 FUN_042297 0 0 14 0 2 NA NA NA NA NA NA NA 2300 FUN_042295 0 0 15 0 0 NA NA NA NA NA NA NA 2301 FUN_042294 15 6 22 0 150 NA NA NA NA NA NA NA 2302 FUN_023029 33 0 17 1 66 NA NA NA NA NA NA NA 2303 FUN_023028 99 0 73 43 20 NA NA NA NA NA NA NA 2304 FUN_023025 262 333 157 195 353 ptg000017l:2751249-2755599 Q7TMF2 3.15e-23 3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-exonuclease 1) Mus musculus (Mouse) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; RNA-mediated gene silencing [GO:0031047]; rRNA 3'-end processing [GO:0031125] GO:0000175; GO:0000467; GO:0005634; GO:0005730; GO:0005737; GO:0008408; GO:0019843; GO:0031047; GO:0031125; GO:0043022; GO:0046872; GO:0071204; GO:0071207 2305 FUN_023024 123 51 27 72 54 ptg000017l:2738288-2750128 Q32KH7 8.8e-21 Arylsulfatase I (ASI) (EC 3.1.6.-) Canis lupus familiaris (Dog) (Canis familiaris) NA GO:0005576; GO:0005783; GO:0008484; GO:0046872 2306 FUN_023027 29 25 65 27 251 NA NA NA NA NA NA NA 2307 FUN_023026 952 550 450 708 698 NA NA NA NA NA NA NA 2308 FUN_023021 0 0 0 0 6 ptg000017l:2701586-2704196 Q96DM1 2.42e-27 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 2309 FUN_023020 2291 1414 923 2128 1457 NA NA NA NA NA NA NA 2310 FUN_023023 299 110 166 303 147 ptg000017l:2735686-2736718 Q91175 3.06e-46 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 2311 FUN_023022 15 0 0 0 36 NA NA NA NA NA NA NA 2312 FUN_036856 0 0 4 0 25 NA NA NA NA NA NA NA 2313 FUN_036857 70 57 56 48 171 ptg000026l:2708781-2711215 Q4UMH6 1.37e-63 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 2314 FUN_036857 70 57 56 48 171 ptg000026l:2708781-2711215 Q4UMH6 1.66e-56 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 2315 FUN_036857 70 57 56 48 171 ptg000026l:2708781-2711215 Q4UMH6 2.93e-52 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 2316 FUN_036857 70 57 56 48 171 ptg000026l:2708781-2711215 Q4UMH6 1.97e-43 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 2317 FUN_036857 70 57 56 48 171 ptg000026l:2708781-2711215 Q4UMH6 1.24e-42 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 2318 FUN_036854 3638 4368 1746 1780 2657 NA NA NA NA NA NA NA 2319 FUN_036852 1927 3405 525 2602 812 ptg000026l:2690327-2692625 Q4R0J7 3.81e-28 D-arabinitol dehydrogenase 1 (EC 1.1.1.287) (NADP-dependent D-arabitol dehydrogenase) Uromyces fabae (Rust fungus) carbohydrate metabolic process [GO:0005975] GO:0005975; GO:0008270; GO:0033709; GO:0042995; GO:0052677 2320 FUN_036853 2493 1918 856 2038 696 NA NA NA NA NA NA NA 2321 FUN_036850 18793 13635 6360 21137 6670 NA NA NA NA NA NA NA 2322 FUN_036851 0 7 0 1 1 NA NA NA NA NA NA NA 2323 FUN_036858 2983 3086 2396 2130 131 ptg000026l:2713227-2721961 P22412 1.37e-28 Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Microsomal dipeptidase) (Renal dipeptidase) Sus scrofa (Pig) antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to insulin stimulus [GO:0032869]; cellular response to nitric oxide [GO:0071732]; cellular response to xenobiotic stimulus [GO:0071466]; glutathione catabolic process [GO:0006751]; GPI anchor release [GO:0006507]; homocysteine metabolic process [GO:0050667]; leukotriene D4 catabolic process [GO:1901749]; leukotriene metabolic process [GO:0006691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; proteolysis [GO:0006508] GO:0005615; GO:0005789; GO:0005886; GO:0006507; GO:0006508; GO:0006691; GO:0006751; GO:0008270; GO:0008800; GO:0016324; GO:0016805; GO:0016999; GO:0030336; GO:0031528; GO:0032869; GO:0034235; GO:0042802; GO:0043027; GO:0043066; GO:0043154; GO:0045177; GO:0050667; GO:0070573; GO:0071277; GO:0071466; GO:0071732; GO:0072341; GO:1901749 2324 FUN_036859 1030 891 1917 1164 382 ptg000026l:2722212-2730649 P22412 1.78e-28 Dipeptidase 1 (EC 3.4.13.19) (Beta-lactamase) (EC 3.5.2.6) (Microsomal dipeptidase) (Renal dipeptidase) Sus scrofa (Pig) antibiotic metabolic process [GO:0016999]; cellular response to calcium ion [GO:0071277]; cellular response to insulin stimulus [GO:0032869]; cellular response to nitric oxide [GO:0071732]; cellular response to xenobiotic stimulus [GO:0071466]; glutathione catabolic process [GO:0006751]; GPI anchor release [GO:0006507]; homocysteine metabolic process [GO:0050667]; leukotriene D4 catabolic process [GO:1901749]; leukotriene metabolic process [GO:0006691]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; proteolysis [GO:0006508] GO:0005615; GO:0005789; GO:0005886; GO:0006507; GO:0006508; GO:0006691; GO:0006751; GO:0008270; GO:0008800; GO:0016324; GO:0016805; GO:0016999; GO:0030336; GO:0031528; GO:0032869; GO:0034235; GO:0042802; GO:0043027; GO:0043066; GO:0043154; GO:0045177; GO:0050667; GO:0070573; GO:0071277; GO:0071466; GO:0071732; GO:0072341; GO:1901749 2325 FUN_033777 1548 1111 943 1351 922 NA NA NA NA NA NA NA 2326 FUN_023797 0 51 0 47 3 NA NA NA NA NA NA NA 2327 FUN_023796 165 118 93 162 153 NA NA NA NA NA NA NA 2328 FUN_023795 2081 1262 825 2432 1970 ptg000017l:11220365-11276672 P04146 7.22e-31 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 2329 FUN_023795 2081 1262 825 2432 1970 ptg000017l:11220365-11276672 P04146 7.22e-31 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 2330 FUN_023795 2081 1262 825 2432 1970 ptg000017l:11220365-11276672 P04146 8.2e-24 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 2331 FUN_023793 22 1 3 7 8 NA NA NA NA NA NA NA 2332 FUN_023791 103 0 56 187 48 ptg000017l:11173746-11202290 Q9NBX4 4.66e-32 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 2333 FUN_023790 281 291 116 299 298 ptg000017l:11138790-11168570 P20825 1.24e-28 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 2334 FUN_023790 281 291 116 299 298 ptg000017l:11138790-11168570 P20825 1.24e-28 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 2335 FUN_023799 9 4 17 26 24 NA NA NA NA NA NA NA 2336 FUN_023798 2547 1845 1477 3689 1940 ptg000017l:11308006-11412727 O60290 1.14e-25 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 2337 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 2.43e-50 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2338 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 6.26e-37 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2339 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 6.26e-37 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2340 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 3.63e-29 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2341 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 3.63e-29 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2342 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 9.71e-28 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2343 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 2.75e-27 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2344 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 2.06e-22 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2345 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 2.13e-22 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2346 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 4.61e-22 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2347 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 9.16e-22 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2348 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 1.93e-21 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2349 FUN_010919 1432 1019 1031 1372 1327 ptg000007l:4213722-4252397 B2RQC6 3.04e-21 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] Mus musculus (Mouse) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; citrulline biosynthetic process [GO:0019240]; glutamine metabolic process [GO:0006541]; nitrogen compound metabolic process [GO:0006807]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; response to insulin [GO:0032868]; response to starvation [GO:0042594]; UDP biosynthetic process [GO:0006225]; UTP biosynthetic process [GO:0006228]; xenobiotic metabolic process [GO:0006805] GO:0002134; GO:0004070; GO:0004088; GO:0004151; GO:0004672; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006207; GO:0006225; GO:0006228; GO:0006541; GO:0006805; GO:0006807; GO:0008270; GO:0016363; GO:0016597; GO:0018107; GO:0019240; GO:0019899; GO:0032868; GO:0032991; GO:0036094; GO:0042594; GO:0042802; GO:0042995; GO:0043025; GO:0043195; GO:0044205; GO:0046777 2350 FUN_010918 199 197 207 257 141 NA NA NA NA NA NA NA 2351 FUN_010913 2574 1024 850 1205 1202 ptg000007l:4152210-4157939 R1CW23 3.13e-40 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 2352 FUN_010911 38675 31643 25798 21455 21364 ptg000007l:4146324-4147011 R1CW23 1.85e-91 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 2353 FUN_010917 37 0 0 59 0 NA NA NA NA NA NA NA 2354 FUN_010916 24188 8983 10015 10742 4856 ptg000007l:4180830-4183822 R1CW23 5.16e-102 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 2355 FUN_010915 14158 4736 3121 3927 4728 ptg000007l:4164214-4170836 R1CW23 5.93e-98 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 2356 FUN_010914 8353 3946 2242 2968 4599 ptg000007l:4157990-4158926 R1CW23 1.37e-68 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 2357 FUN_041678 9842 16617 16476 5962 4950 ptg000035l:6464728-6466666 P42577 6.54e-23 Soma ferritin (EC 1.16.3.1) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0005737; GO:0006826; GO:0006879; GO:0008199 2358 FUN_041679 282425 348843 272279 261393 169224 NA NA NA NA NA NA NA 2359 FUN_041670 14 0 13 39 3 NA NA NA NA NA NA NA 2360 FUN_041671 640 697 433 490 310 ptg000035l:6427986-6432014 A2VE52 1.75e-29 Oligoribonuclease, mitochondrial (EC 3.1.15.-) (RNA exonuclease 2 homolog) (Small fragment nuclease) Bos taurus (Bovine) NA GO:0000175; GO:0000287; GO:0003676; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005758; GO:0005759; GO:0005925; GO:0008296; GO:0008408 2361 FUN_041672 702 374 354 761 586 NA NA NA NA NA NA NA 2362 FUN_041673 329 125 262 406 337 NA NA NA NA NA NA NA 2363 FUN_041674 6728 8290 4693 3952 2096 ptg000035l:6444755-6446802 Q9CZL5 1.56e-44 Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0004505; GO:0005634; GO:0005739; GO:0006729; GO:0008124; GO:0042802; GO:0045893 2364 FUN_041675 6163 6554 3406 4279 3431 NA NA NA NA NA NA NA 2365 FUN_041676 691035 1004875 794040 484242 411484 ptg000035l:6452644-6454370 P25319 2.76e-23 Ferritin-1 heavy chain (EC 1.16.3.1) Schistosoma mansoni (Blood fluke) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0006826; GO:0006879; GO:0008199 2366 FUN_041676 691035 1004875 794040 484242 411484 ptg000035l:6452644-6454370 P25319 2.76e-23 Ferritin-1 heavy chain (EC 1.16.3.1) Schistosoma mansoni (Blood fluke) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0006826; GO:0006879; GO:0008199 2367 FUN_041676 691035 1004875 794040 484242 411484 ptg000035l:6452644-6454370 P25319 2.76e-23 Ferritin-1 heavy chain (EC 1.16.3.1) Schistosoma mansoni (Blood fluke) cellular iron ion homeostasis [GO:0006879]; iron ion transport [GO:0006826] GO:0004322; GO:0006826; GO:0006879; GO:0008199 2368 FUN_041677 182802 252618 185770 162912 129141 NA NA NA NA NA NA NA 2369 FUN_022772 4675 4382 2470 4670 4148 ptg000016l:12844889-12853412 P23330 1.25e-32 Tubulin gamma-1 chain (Gamma-1-tubulin) (xGAM) Xenopus laevis (African clawed frog) cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] GO:0000930; GO:0005525; GO:0005737; GO:0005813; GO:0005827; GO:0007020; GO:0031122; GO:1990498 2370 FUN_022772 4675 4382 2470 4670 4148 ptg000016l:12844889-12853412 P23330 1.25e-32 Tubulin gamma-1 chain (Gamma-1-tubulin) (xGAM) Xenopus laevis (African clawed frog) cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] GO:0000930; GO:0005525; GO:0005737; GO:0005813; GO:0005827; GO:0007020; GO:0031122; GO:1990498 2371 FUN_022772 4675 4382 2470 4670 4148 ptg000016l:12844889-12853412 P23330 1.25e-32 Tubulin gamma-1 chain (Gamma-1-tubulin) (xGAM) Xenopus laevis (African clawed frog) cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] GO:0000930; GO:0005525; GO:0005737; GO:0005813; GO:0005827; GO:0007020; GO:0031122; GO:1990498 2372 FUN_022772 4675 4382 2470 4670 4148 ptg000016l:12844889-12853412 P23330 9.37e-22 Tubulin gamma-1 chain (Gamma-1-tubulin) (xGAM) Xenopus laevis (African clawed frog) cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] GO:0000930; GO:0005525; GO:0005737; GO:0005813; GO:0005827; GO:0007020; GO:0031122; GO:1990498 2373 FUN_022772 4675 4382 2470 4670 4148 ptg000016l:12844889-12853412 P23330 9.37e-22 Tubulin gamma-1 chain (Gamma-1-tubulin) (xGAM) Xenopus laevis (African clawed frog) cytoplasmic microtubule organization [GO:0031122]; microtubule nucleation [GO:0007020] GO:0000930; GO:0005525; GO:0005737; GO:0005813; GO:0005827; GO:0007020; GO:0031122; GO:1990498 2374 FUN_006374 148 53 49 52 37 NA NA NA NA NA NA NA 2375 FUN_022770 390 308 271 559 422 ptg000016l:12834759-12836084 Q91WN1 6.09e-53 DnaJ homolog subfamily C member 9 Mus musculus (Mouse) nucleosome assembly [GO:0006334]; positive regulation of ATP-dependent activity [GO:0032781] GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006334; GO:0031072; GO:0032781; GO:0042393; GO:0051087; GO:0101031 2376 FUN_022771 1251 812 537 822 727 ptg000016l:12837968-12840492 P21327 7.74e-26 Inositol polyphosphate 1-phosphatase (IPP) (IPPase) (EC 3.1.3.57) Bos taurus (Bovine) inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] GO:0004441; GO:0046854; GO:0046855; GO:0046872; GO:0052829 2377 FUN_009117 105 123 43 55 34 ptg000004l:2896988-2901311 Q96AY4 5.67e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2378 FUN_009117 105 123 43 55 34 ptg000004l:2896988-2901311 Q96AY4 3.92e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2379 FUN_009117 105 123 43 55 34 ptg000004l:2896988-2901311 Q96AY4 3.23e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2380 FUN_022775 10923 12393 3432 4738 6866 ptg000016l:12859406-12862412 P79110 6.16e-28 Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein) Bos taurus (Bovine) mitochondrial citrate transmembrane transport [GO:0006843] GO:0005739; GO:0005743; GO:0006843; GO:0015297; GO:0071913 2381 FUN_022775 10923 12393 3432 4738 6866 ptg000016l:12859406-12862412 P79110 2.94e-25 Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein) Bos taurus (Bovine) mitochondrial citrate transmembrane transport [GO:0006843] GO:0005739; GO:0005743; GO:0006843; GO:0015297; GO:0071913 2382 FUN_022775 10923 12393 3432 4738 6866 ptg000016l:12859406-12862412 P79110 2.94e-25 Tricarboxylate transport protein, mitochondrial (Citrate transport protein) (CTP) (Solute carrier family 25 member 1) (Tricarboxylate carrier protein) Bos taurus (Bovine) mitochondrial citrate transmembrane transport [GO:0006843] GO:0005739; GO:0005743; GO:0006843; GO:0015297; GO:0071913 2383 FUN_009119 0 0 0 0 13 NA NA NA NA NA NA NA 2384 FUN_009118 6 62 24 1 55 NA NA NA NA NA NA NA 2385 FUN_022778 7937 6526 3430 5867 4672 NA NA NA NA NA NA NA 2386 FUN_022779 1343 1254 1271 1059 845 ptg000016l:12894199-12895417 Q9YGN6 1.81e-54 Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-) Xenopus laevis (African clawed frog) base-excision repair [GO:0006284] GO:0003677; GO:0005634; GO:0006284; GO:0017065 2387 FUN_042134 925 127 634 415 1054 ptg000036l:1062519-1074104 E9Q236 3.41e-65 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 2388 FUN_042134 925 127 634 415 1054 ptg000036l:1062519-1074104 E9Q236 1.57e-51 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 2389 FUN_042134 925 127 634 415 1054 ptg000036l:1062519-1074104 E9Q236 6.8e-28 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 2390 FUN_042134 925 127 634 415 1054 ptg000036l:1062519-1074104 E9Q236 4.99e-26 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 2391 FUN_014117 1094 1221 916 833 670 NA NA NA NA NA NA NA 2392 FUN_029897 19 3 9 4 46 NA NA NA NA NA NA NA 2393 FUN_029894 20 5 13 4 72 NA NA NA NA NA NA NA 2394 FUN_029895 7 4 7 3 32 NA NA NA NA NA NA NA 2395 FUN_014113 0 6 2 0 0 NA NA NA NA NA NA NA 2396 FUN_029893 32 19 26 52 73 NA NA NA NA NA NA NA 2397 FUN_014111 0 0 0 0 6 NA NA NA NA NA NA NA 2398 FUN_029891 2729 1652 976 2209 1631 ptg000023l:7502349-7624044 Q7LHG5 1.17e-87 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 2399 FUN_029891 2729 1652 976 2209 1631 ptg000023l:7502349-7624044 Q7LHG5 9.24e-35 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 2400 FUN_006373 30 0 6 19 147 NA NA NA NA NA NA NA 2401 FUN_029898 27 0 9 1 21 NA NA NA NA NA NA NA 2402 FUN_029899 13 5 7 6 0 NA NA NA NA NA NA NA 2403 FUN_010703 2338 2354 1572 1546 430 NA NA NA NA NA NA NA 2404 FUN_040109 2731 2352 1098 2822 1819 NA NA NA NA NA NA NA 2405 FUN_040108 15289 8137 2425 7179 14785 NA NA NA NA NA NA NA 2406 FUN_040101 1164 858 626 1965 1872 NA NA NA NA NA NA NA 2407 FUN_040103 1018 876 538 955 855 ptg000031l:4225904-4236045 Q498M4 1.69e-23 WD repeat-containing protein 5 Rattus norvegicus (Rat) gluconeogenesis [GO:0006094]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of histone H3-K4 methylation [GO:0051572]; neuron projection development [GO:0031175]; peptidyl-lysine methylation [GO:0018022]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; skeletal system development [GO:0001501]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0001501; GO:0005634; GO:0006094; GO:0006355; GO:0006357; GO:0018022; GO:0031063; GO:0031175; GO:0035064; GO:0035097; GO:0042393; GO:0042800; GO:0043966; GO:0043981; GO:0043982; GO:0043984; GO:0044154; GO:0044545; GO:0044665; GO:0044666; GO:0045722; GO:0045815; GO:0045995; GO:0048188; GO:0051302; GO:0051568; GO:0051571; GO:0051572; GO:0051726; GO:0071339; GO:0090043; GO:0140672; GO:1900095 2408 FUN_040103 1018 876 538 955 855 ptg000031l:4225904-4236045 Q498M4 1.69e-23 WD repeat-containing protein 5 Rattus norvegicus (Rat) gluconeogenesis [GO:0006094]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone H3-K4 methylation [GO:0051568]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; negative regulation of histone H3-K4 methylation [GO:0051572]; neuron projection development [GO:0031175]; peptidyl-lysine methylation [GO:0018022]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of histone H3-K4 methylation [GO:0051571]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043]; skeletal system development [GO:0001501]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0001501; GO:0005634; GO:0006094; GO:0006355; GO:0006357; GO:0018022; GO:0031063; GO:0031175; GO:0035064; GO:0035097; GO:0042393; GO:0042800; GO:0043966; GO:0043981; GO:0043982; GO:0043984; GO:0044154; GO:0044545; GO:0044665; GO:0044666; GO:0045722; GO:0045815; GO:0045995; GO:0048188; GO:0051302; GO:0051568; GO:0051571; GO:0051572; GO:0051726; GO:0071339; GO:0090043; GO:0140672; GO:1900095 2409 FUN_040102 995 1459 702 2361 1904 NA NA NA NA NA NA NA 2410 FUN_040107 31656 32822 17042 42603 33088 ptg000031l:4260936-4265150 P19208 1.29e-153 Heat shock 70 kDa protein C Caenorhabditis briggsae cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; protein refolding [GO:0042026]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005634; GO:0005737; GO:0005788; GO:0016020; GO:0016887; GO:0030433; GO:0030968; GO:0031072; GO:0034620; GO:0034663; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 2411 FUN_040107 31656 32822 17042 42603 33088 ptg000031l:4260936-4265150 P19208 5.87e-50 Heat shock 70 kDa protein C Caenorhabditis briggsae cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; protein refolding [GO:0042026]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005634; GO:0005737; GO:0005788; GO:0016020; GO:0016887; GO:0030433; GO:0030968; GO:0031072; GO:0034620; GO:0034663; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 2412 FUN_040107 31656 32822 17042 42603 33088 ptg000031l:4260936-4265150 P19208 4.73e-40 Heat shock 70 kDa protein C Caenorhabditis briggsae cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; protein refolding [GO:0042026]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005634; GO:0005737; GO:0005788; GO:0016020; GO:0016887; GO:0030433; GO:0030968; GO:0031072; GO:0034620; GO:0034663; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 2413 FUN_040107 31656 32822 17042 42603 33088 ptg000031l:4260936-4265150 P19208 2.89e-26 Heat shock 70 kDa protein C Caenorhabditis briggsae cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum unfolded protein response [GO:0030968]; protein refolding [GO:0042026]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005634; GO:0005737; GO:0005788; GO:0016020; GO:0016887; GO:0030433; GO:0030968; GO:0031072; GO:0034620; GO:0034663; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 2414 FUN_010707 270 265 89 589 241 NA NA NA NA NA NA NA 2415 FUN_010705 4 0 9 6 21 NA NA NA NA NA NA NA 2416 FUN_015244 4 6 0 29 20 NA NA NA NA NA NA NA 2417 FUN_015245 3620 2788 2015 3854 4304 NA NA NA NA NA NA NA 2418 FUN_015246 8 0 0 23 21 NA NA NA NA NA NA NA 2419 FUN_015247 0 0 0 43 5 NA NA NA NA NA NA NA 2420 FUN_015240 310 185 19 312 70 NA NA NA NA NA NA NA 2421 FUN_015241 28 15 42 20 199 NA NA NA NA NA NA NA 2422 FUN_015242 491 936 292 1746 237 ptg000009l:7851934-7854640 B3EX00 6.91e-124 Uncharacterized skeletal organic matrix protein 1 (Uncharacterized SOMP-1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 2423 FUN_018358 356 120 252 386 317 NA NA NA NA NA NA NA 2424 FUN_015248 0 49 79 100 61 NA NA NA NA NA NA NA 2425 FUN_015249 102 42 21 117 41 NA NA NA NA NA NA NA 2426 FUN_024329 113 14 108 34 110 ptg000018l:4983579-4988008 Q21565 6.04e-74 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 2427 FUN_024328 345 33 80 189 80 ptg000018l:4955492-4960760 Q21565 6.53e-69 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 2428 FUN_035414 1994 1902 1413 2177 2256 NA NA NA NA NA NA NA 2429 FUN_024323 87 0 0 0 205 ptg000018l:4904892-4915475 Q7RTR2 3.88e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2430 FUN_024321 15 19 3 15 5 ptg000018l:4894093-4896994 Q8K3Z0 1.94e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 2431 FUN_024327 27 68 38 111 182 NA NA NA NA NA NA NA 2432 FUN_024326 69 8 48 62 114 NA NA NA NA NA NA NA 2433 FUN_024325 50 0 0 0 260 ptg000018l:4922720-4924916 Q9Y239 2.66e-23 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0006952; GO:0006954; GO:0007165; GO:0007249; GO:0007254; GO:0008656; GO:0009595; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042834; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 2434 FUN_024324 51 0 17 0 157 NA NA NA NA NA NA NA 2435 FUN_038409 47 258 69 112 67 NA NA NA NA NA NA NA 2436 FUN_038403 961 806 417 623 572 ptg000027l:6834205-6838134 A3KPA3 5.67e-26 N-alpha-acetyltransferase 60 (EC 2.3.1.259) (Histone acetyltransferase type B protein 4) (HAT4) (EC 2.3.1.48) (N-acetyltransferase 15) (N-alpha-acetyltransferase F) (NatF) Danio rerio (Zebrafish) (Brachydanio rerio) cell population proliferation [GO:0008283]; chromosome segregation [GO:0007059]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; nucleosome assembly [GO:0006334] GO:0000139; GO:0004402; GO:0004596; GO:0006334; GO:0006474; GO:0007059; GO:0008283; GO:0010485; GO:0017196; GO:0042803; GO:0043966; GO:0043967 2437 FUN_038402 1373 1722 725 1314 1133 NA NA NA NA NA NA NA 2438 FUN_038401 935 742 660 1306 1221 ptg000027l:6811017-6812427 P61754 5.81e-61 Transcription factor SOX-9 Pongo pygmaeus (Bornean orangutan) cAMP-mediated signaling [GO:0019933]; cartilage condensation [GO:0001502]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cellular response to BMP stimulus [GO:0071773]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to heparin [GO:0071504]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; chondrocyte differentiation [GO:0002062]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte hypertrophy [GO:0003415]; chromatin remodeling [GO:0006338]; cochlea morphogenesis [GO:0090103]; endocardial cushion morphogenesis [GO:0003203]; epidermal growth factor receptor signaling pathway [GO:0007173]; epithelial cell proliferation involved in prostatic bud elongation [GO:0060517]; epithelial to mesenchymal transition [GO:0001837]; ERK1 and ERK2 cascade [GO:0070371]; growth plate cartilage chondrocyte growth [GO:0003430]; hair follicle development [GO:0001942]; heart valve development [GO:0003170]; heart valve morphogenesis [GO:0003179]; intestinal epithelial structure maintenance [GO:0060729]; male germ-line sex determination [GO:0019100]; male gonad development [GO:0008584]; metanephric nephron tubule formation [GO:0072289]; morphogenesis of a branching epithelium [GO:0061138]; negative regulation of apoptotic process [GO:0043066]; negative regulation of biomineral tissue development [GO:0070168]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of immune system process [GO:0002683]; negative regulation of myoblast differentiation [GO:0045662]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of photoreceptor cell differentiation [GO:0046533]; neural crest cell fate specification [GO:0014036]; nucleosome assembly [GO:0006334]; otic vesicle formation [GO:0030916]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cartilage development [GO:0061036]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of kidney development [GO:0090184]; positive regulation of male gonad development [GO:2000020]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mesenchymal stem cell differentiation [GO:2000741]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein kinase B signaling [GO:0043491]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of cartilage development [GO:0061035]; regulation of cell cycle process [GO:0010564]; regulation of cell population proliferation [GO:0042127]; regulation of cell proliferation involved in tissue homeostasis [GO:0060784]; renal vesicle induction [GO:0072034]; response to fatty acid [GO:0070542]; retina development in camera-type eye [GO:0060041]; retinal rod cell differentiation [GO:0060221]; Sertoli cell differentiation [GO:0060008]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; somatic stem cell population maintenance [GO:0035019]; spermatogenesis [GO:0007283]; tissue homeostasis [GO:0001894] GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0001501; GO:0001502; GO:0001708; GO:0001837; GO:0001894; GO:0001934; GO:0001942; GO:0002053; GO:0002062; GO:0002683; GO:0003170; GO:0003179; GO:0003203; GO:0003413; GO:0003415; GO:0003430; GO:0003677; GO:0003682; GO:0003700; GO:0005634; GO:0006334; GO:0006338; GO:0007165; GO:0007173; GO:0007283; GO:0008284; GO:0008584; GO:0010564; GO:0010628; GO:0010634; GO:0014036; GO:0014068; GO:0019100; GO:0019933; GO:0030279; GO:0030858; GO:0030916; GO:0032331; GO:0032332; GO:0032991; GO:0035019; GO:0042127; GO:0042981; GO:0043066; GO:0043491; GO:0043565; GO:0045662; GO:0045668; GO:0045892; GO:0045944; GO:0046322; GO:0046533; GO:0050679; GO:0050680; GO:0051216; GO:0060008; GO:0060041; GO:0060221; GO:0060517; GO:0060729; GO:0060784; GO:0061035; GO:0061036; GO:0061138; GO:0065003; GO:0070168; GO:0070371; GO:0070542; GO:0071260; GO:0071364; GO:0071504; GO:0071560; GO:0071773; GO:0072034; GO:0072289; GO:0090090; GO:0090103; GO:0090184; GO:0090190; GO:2000020; GO:2000741 2439 FUN_038400 4004 2579 2042 3622 2585 NA NA NA NA NA NA NA 2440 FUN_038406 56 31 37 173 140 NA NA NA NA NA NA NA 2441 FUN_038405 668 175 262 492 724 NA NA NA NA NA NA NA 2442 FUN_038404 820 578 262 788 590 ptg000027l:6839376-6843540 P9WM79 4.19e-77 Probable polyglutamine synthesis accessory protein Rv0574c Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) NA NA 2443 FUN_028859 14 9 8 19 0 NA NA NA NA NA NA NA 2444 FUN_023809 5 0 21 2 114 NA NA NA NA NA NA NA 2445 FUN_023808 0 0 0 0 35 NA NA NA NA NA NA NA 2446 FUN_028851 116 20 19 66 68 ptg000022l:5015536-5019620 P0C1B3 3.18e-51 Alpha-amylase A type-1/2 (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (Taka-amylase A) (TAA) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) carbohydrate catabolic process [GO:0016052] GO:0004556; GO:0005509; GO:0005576; GO:0009277; GO:0016052; GO:0030287; GO:0030428; GO:0031521; GO:0032163 2447 FUN_028850 60 91 38 47 48 NA NA NA NA NA NA NA 2448 FUN_028852 0 18 0 0 0 NA NA NA NA NA NA NA 2449 FUN_023803 17 9 14 0 37 NA NA NA NA NA NA NA 2450 FUN_023800 91 0 63 38 240 NA NA NA NA NA NA NA 2451 FUN_034383 36 92 145 147 86 NA NA NA NA NA NA NA 2452 FUN_034385 1079 652 312 723 594 NA NA NA NA NA NA NA 2453 FUN_034386 76 30 36 26 64 NA NA NA NA NA NA NA 2454 FUN_034387 1786 1649 1119 1330 1018 NA NA NA NA NA NA NA 2455 FUN_035733 17250 11310 11442 13204 8486 ptg000025l:11071437-11076399 Q26636 8.58e-22 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 2456 FUN_015939 128 21 13 84 12 ptg000009l:18235409-18242439 P0CP97 4.5e-27 FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005783; GO:0061077 2457 FUN_032599 337 83 43 4 304 NA NA NA NA NA NA NA 2458 FUN_042683 0 3 2 5 6 NA NA NA NA NA NA NA 2459 FUN_041462 1 0 0 0 46 ptg000035l:3871596-3873835 F1N2N9 2.16e-43 Outer dynein arm-docking complex subunit 1 Bos taurus (Bovine) cilium movement [GO:0003341]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005930; GO:0036158; GO:0120228 2460 FUN_042684 1 2 2 3 11 NA NA NA NA NA NA NA 2461 FUN_016406 74 0 97 160 84 NA NA NA NA NA NA NA 2462 FUN_016405 49 0 36 37 0 NA NA NA NA NA NA NA 2463 FUN_016404 7 4 17 8 14 NA NA NA NA NA NA NA 2464 FUN_006921 46 6 26 12 18 NA NA NA NA NA NA NA 2465 FUN_032590 31 0 51 0 269 ptg000023l:33531452-33623644 P04323 1.66e-71 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 2466 FUN_006920 1292 1501 584 1054 909 ptg000001l:18328385-18336579 B3EWY9 3.86e-40 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 2467 FUN_004718 807 344 246 376 438 NA NA NA NA NA NA NA 2468 FUN_006923 1327 1555 620 1473 906 ptg000001l:18380996-18385778 Q9WV04 2.57e-63 Kinesin-like protein KIF9 Mus musculus (Mouse) extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of flagellated sperm motility [GO:1901317]; regulation of podosome assembly [GO:0071801] GO:0002102; GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0022617; GO:0031982; GO:0036126; GO:0042802; GO:0071801; GO:1901317; GO:1903008 2469 FUN_006923 1327 1555 620 1473 906 ptg000001l:18380996-18385778 Q9WV04 2.09e-52 Kinesin-like protein KIF9 Mus musculus (Mouse) extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of flagellated sperm motility [GO:1901317]; regulation of podosome assembly [GO:0071801] GO:0002102; GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0022617; GO:0031982; GO:0036126; GO:0042802; GO:0071801; GO:1901317; GO:1903008 2470 FUN_006923 1327 1555 620 1473 906 ptg000001l:18380996-18385778 Q9WV04 1e-25 Kinesin-like protein KIF9 Mus musculus (Mouse) extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of flagellated sperm motility [GO:1901317]; regulation of podosome assembly [GO:0071801] GO:0002102; GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0022617; GO:0031982; GO:0036126; GO:0042802; GO:0071801; GO:1901317; GO:1903008 2471 FUN_006923 1327 1555 620 1473 906 ptg000001l:18380996-18385778 Q9WV04 8.36e-21 Kinesin-like protein KIF9 Mus musculus (Mouse) extracellular matrix disassembly [GO:0022617]; microtubule-based movement [GO:0007018]; organelle disassembly [GO:1903008]; regulation of flagellated sperm motility [GO:1901317]; regulation of podosome assembly [GO:0071801] GO:0002102; GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0022617; GO:0031982; GO:0036126; GO:0042802; GO:0071801; GO:1901317; GO:1903008 2472 FUN_004719 350 351 166 275 393 NA NA NA NA NA NA NA 2473 FUN_006922 471 378 270 479 232 NA NA NA NA NA NA NA 2474 FUN_003568 2311 7244 2734 10865 10487 ntLink_8:12775931-12776771 R1CW23 1.07e-101 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 2475 FUN_031438 30 8 9 11 6 NA NA NA NA NA NA NA 2476 FUN_027002 7 78 0 0 129 NA NA NA NA NA NA NA 2477 FUN_027001 0 0 0 0 8 NA NA NA NA NA NA NA 2478 FUN_004710 190 206 176 541 267 NA NA NA NA NA NA NA 2479 FUN_015518 0 0 0 32 11 NA NA NA NA NA NA NA 2480 FUN_004711 1330 712 670 1315 1277 NA NA NA NA NA NA NA 2481 FUN_016408 13475 10003 6312 9113 7172 NA NA NA NA NA NA NA 2482 FUN_031710 887 867 690 1202 727 ptg000023l:24634366-24640446 Q0V989 1.62e-34 Coiled-coil domain-containing protein 85C Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005912; GO:0005923 2483 FUN_004713 0 0 0 43 11 ntLink_8:26123572-26126578 Q13639 2.42e-23 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) Homo sapiens (Human) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; regulation of appetite [GO:0032098] GO:0004993; GO:0005737; GO:0005768; GO:0005886; GO:0007186; GO:0007187; GO:0007198; GO:0007268; GO:0016020; GO:0030425; GO:0030594; GO:0032098; GO:0045202; GO:0051378 2484 FUN_004833 4246 1766 2135 4491 3946 ntLink_8:27562171-27638515 Q6JAN0 2.95e-30 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 2485 FUN_004833 4246 1766 2135 4491 3946 ntLink_8:27562171-27638515 Q6JAN0 2.15e-23 Adhesion G-protein coupled receptor V1 (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell surface receptor signaling pathway [GO:0007166]; cellular response to calcium ion [GO:0071277]; eye photoreceptor cell development [GO:0042462]; negative regulation of adenylate cyclase activity [GO:0007194]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein kinase C signaling [GO:0090037]; regulation of protein stability [GO:0031647]; self proteolysis [GO:0097264]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0001917; GO:0001965; GO:0004930; GO:0005737; GO:0007166; GO:0007194; GO:0007601; GO:0007605; GO:0010739; GO:0010855; GO:0016787; GO:0031647; GO:0032420; GO:0042462; GO:0060171; GO:0071277; GO:0090037; GO:0097264 2486 FUN_031711 493 221 309 681 998 ptg000023l:24641119-24650746 Q8NI60 1.86e-29 Atypical kinase COQ8A, mitochondrial (EC 2.7.-.-) (Chaperone activity of bc1 complex-like) (Chaperone-ABC1-like) (Coenzyme Q protein 8A) (aarF domain-containing protein kinase 3) Homo sapiens (Human) phosphorylation [GO:0016310]; ubiquinone biosynthetic process [GO:0006744] GO:0005524; GO:0005739; GO:0006744; GO:0016301; GO:0016310; GO:0031314; GO:0043531 2487 FUN_004832 685 922 319 849 376 NA NA NA NA NA NA NA 2488 FUN_022444 26 26 109 34 177 ptg000016l:9079273-9081324 Q64464 9.76e-55 Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13) Mus musculus (Mouse) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; positive regulation of gene expression [GO:0010628]; retinoic acid metabolic process [GO:0042573]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0010628; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0034875; GO:0042178; GO:0042573; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 2489 FUN_022444 26 26 109 34 177 ptg000016l:9079273-9081324 Q64464 6.13e-24 Cytochrome P450 3A13 (EC 1.14.14.1) (CYPIIIA13) Mus musculus (Mouse) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; lipid hydroxylation [GO:0002933]; oxidative demethylation [GO:0070989]; positive regulation of gene expression [GO:0010628]; retinoic acid metabolic process [GO:0042573]; steroid metabolic process [GO:0008202]; xenobiotic catabolic process [GO:0042178] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0010628; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0034875; GO:0042178; GO:0042573; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 2490 FUN_031713 947 1099 316 2975 1968 ptg000023l:24660002-24662348 E7FAM5 1.24e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 2491 FUN_004717 0 15 31 67 32 NA NA NA NA NA NA NA 2492 FUN_031433 4 132 6 0 0 NA NA NA NA NA NA NA 2493 FUN_031715 2023 1264 1227 1502 1056 NA NA NA NA NA NA NA 2494 FUN_017268 68 0 4 281 7 NA NA NA NA NA NA NA 2495 FUN_031716 189 52 26 79 101 ptg000023l:24691192-24693247 P58283 5.66e-94 E3 ubiquitin-protein ligase RNF216 (EC 2.3.2.27) (RING finger protein 216) (RING-type E3 ubiquitin transferase RNF216) (Triad domain-containing protein 3) (UbcM4-interacting protein 83) (Ubiquitin-conjugating enzyme 7-interacting protein 1) Mus musculus (Mouse) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process, modulating synaptic transmission [GO:0099546]; protein K48-linked ubiquitination [GO:0070936]; regulation of defense response to virus by host [GO:0050691]; regulation of interferon-beta production [GO:0032648]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149] GO:0005634; GO:0005654; GO:0005829; GO:0006915; GO:0032648; GO:0043161; GO:0046872; GO:0050691; GO:0061630; GO:0070936; GO:0098685; GO:0098793; GO:0098843; GO:0098978; GO:0099149; GO:0099546 2496 FUN_017264 0 0 0 0 9 NA NA NA NA NA NA NA 2497 FUN_031435 12 0 0 0 6 NA NA NA NA NA NA NA 2498 FUN_017266 0 0 22 15 0 NA NA NA NA NA NA NA 2499 FUN_031717 7 20 60 26 86 ptg000023l:24697052-24699018 F7B113 4.48e-155 Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Sodium/hydrogen exchanger) (Solute carrier family 9 member 9) Equus caballus (Horse) potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of intracellular pH [GO:0051453]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725] GO:0005886; GO:0010008; GO:0015385; GO:0015386; GO:0035725; GO:0042803; GO:0051453; GO:0055037; GO:0071805; GO:0098719; GO:1902600 2500 FUN_017260 0 0 0 0 18 NA NA NA NA NA NA NA 2501 FUN_036005 959 883 576 1282 906 ptg000025l:14386186-14390698 Q6NXR0 1.7e-45 Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952] GO:0003924; GO:0005525; GO:0005789; GO:0006952; GO:0035458 2502 FUN_010641 56 20 29 53 56 NA NA NA NA NA NA NA 2503 FUN_038985 71 96 0 55 13 NA NA NA NA NA NA NA 2504 FUN_038988 0 0 7 0 0 NA NA NA NA NA NA NA 2505 FUN_038989 11 0 0 3 0 NA NA NA NA NA NA NA 2506 FUN_004347 893 473 480 633 803 NA NA NA NA NA NA NA 2507 FUN_004346 2948 1234 1445 2152 1672 ntLink_8:22165444-22174653 Q95ZQ4 2.74e-37 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) Caenorhabditis elegans determination of adult lifespan [GO:0008340]; intracellular signal transduction [GO:0035556]; negative regulation of protein secretion [GO:0050709]; peptidyl-serine phosphorylation [GO:0018105]; pharyngeal pumping [GO:0043050]; positive regulation of dauer larval development [GO:0061066]; positive regulation of protein secretion [GO:0050714]; protein phosphorylation [GO:0006468]; serotonin receptor signaling pathway [GO:0007210] GO:0004674; GO:0004679; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0007210; GO:0008340; GO:0018105; GO:0030424; GO:0035556; GO:0043025; GO:0043050; GO:0050709; GO:0050714; GO:0061066; GO:0106310 2508 FUN_004344 7 3 20 43 0 ntLink_8:22152693-22155993 E7FAM5 8.34e-23 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 2509 FUN_004343 1187 903 541 1044 1120 ntLink_8:22144611-22151521 Q16629 6.23e-24 Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7) Homo sapiens (Human) cellular response to leukemia inhibitory factor [GO:1990830]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006397; GO:0008270; GO:0008380; GO:0016607; GO:0019904; GO:0048025; GO:0051028; GO:0070062; GO:1990830 2510 FUN_004342 1045 668 816 839 1320 NA NA NA NA NA NA NA 2511 FUN_004341 14 40 26 44 15 NA NA NA NA NA NA NA 2512 FUN_004340 290 252 166 816 434 NA NA NA NA NA NA NA 2513 FUN_004349 45 3 33 25 18 NA NA NA NA NA NA NA 2514 FUN_004348 27 11 0 24 0 NA NA NA NA NA NA NA 2515 FUN_027919 0 0 0 41 29 NA NA NA NA NA NA NA 2516 FUN_027918 0 28 0 0 101 NA NA NA NA NA NA NA 2517 FUN_018178 30 12 10 20 67 NA NA NA NA NA NA NA 2518 FUN_018174 106 31 160 304 96 NA NA NA NA NA NA NA 2519 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 1.31e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2520 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 1.2e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2521 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 1.17e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2522 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 1.42e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2523 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 5.98e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2524 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 7.67e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2525 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 8.85e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2526 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 2.42e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2527 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 3e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2528 FUN_018177 16 6 11 505 42 ptg000012l:5394504-5395764 Q96AY4 2.47e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2529 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 1.1e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2530 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 6.49e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2531 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 6.6e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2532 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 9.68e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2533 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 4.94e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2534 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 6.17e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2535 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 2.63e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2536 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 1.37e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2537 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 9.59e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2538 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 8.13e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2539 FUN_018176 335 106 112 1488 379 ptg000012l:5375557-5394185 Q96AY4 1.35e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2540 FUN_027915 22 1293 0 57 2293 NA NA NA NA NA NA NA 2541 FUN_027914 140 159 83 169 87 NA NA NA NA NA NA NA 2542 FUN_027916 32 0 0 47 20 NA NA NA NA NA NA NA 2543 FUN_035411 41 26 21 50 44 NA NA NA NA NA NA NA 2544 FUN_025513 27 25 25 20 34 NA NA NA NA NA NA NA 2545 FUN_025512 58 82 72 171 161 NA NA NA NA NA NA NA 2546 FUN_025511 1495 1505 653 765 859 NA NA NA NA NA NA NA 2547 FUN_025510 232 128 97 296 130 ptg000019l:3697344-3705815 Q8CJ40 3.05e-25 Rootletin (Ciliary rootlet coiled-coil protein) Mus musculus (Mouse) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0097729; GO:0120219; GO:1903566 2548 FUN_025510 232 128 97 296 130 ptg000019l:3697344-3705815 Q8CJ40 1.11e-22 Rootletin (Ciliary rootlet coiled-coil protein) Mus musculus (Mouse) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0097729; GO:0120219; GO:1903566 2549 FUN_025517 2136 1207 1582 2821 2722 NA NA NA NA NA NA NA 2550 FUN_025516 8911 5376 3904 7553 5741 ptg000019l:3744665-3763489 Q5TZA2 1.7e-29 Rootletin (Ciliary rootlet coiled-coil protein) Homo sapiens (Human) cellular homeostasis [GO:0019725]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098]; ciliary basal body organization [GO:0032053]; epithelial structure maintenance [GO:0010669]; establishment of localization in cell [GO:0051649]; establishment of organelle localization [GO:0051656]; photoreceptor cell maintenance [GO:0045494]; positive regulation of cilium assembly [GO:0045724]; positive regulation of protein localization to cilium [GO:1903566]; protein localization [GO:0008104]; protein localization to organelle [GO:0033365] GO:0001917; GO:0003779; GO:0005198; GO:0005200; GO:0005813; GO:0005814; GO:0005829; GO:0005886; GO:0007098; GO:0008104; GO:0010457; GO:0010669; GO:0015629; GO:0019725; GO:0019894; GO:0032053; GO:0033365; GO:0035253; GO:0045494; GO:0045724; GO:0051649; GO:0051656; GO:0070062; GO:0097729; GO:0120219; GO:1903566 2551 FUN_025514 169 74 70 140 163 NA NA NA NA NA NA NA 2552 FUN_025519 231 365 333 443 466 NA NA NA NA NA NA NA 2553 FUN_025518 3251 2437 1350 2520 2121 ptg000019l:3782796-3798445 O95140 2e-25 Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2) Homo sapiens (Human) apoptotic process [GO:0006915]; blastocyst formation [GO:0001825]; camera-type eye morphogenesis [GO:0048593]; mitochondrial fusion [GO:0008053]; mitochondrial membrane organization [GO:0007006]; mitochondrion localization [GO:0051646]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of smooth muscle cell proliferation [GO:0048662]; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [GO:0061734]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of vascular associated smooth muscle cell apoptotic process [GO:1905461]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to mitochondrion [GO:0006626]; response to unfolded protein [GO:0006986] GO:0001825; GO:0003924; GO:0005525; GO:0005739; GO:0005741; GO:0005829; GO:0006626; GO:0006915; GO:0006986; GO:0007006; GO:0008053; GO:0015630; GO:0031625; GO:0034497; GO:0046580; GO:0048593; GO:0048662; GO:0051646; GO:0061734; GO:0120162; GO:1904707; GO:1905461 2554 FUN_010760 163 93 49 49 118 NA NA NA NA NA NA NA 2555 FUN_018799 86 47 53 104 0 NA NA NA NA NA NA NA 2556 FUN_018798 238 36 235 161 197 NA NA NA NA NA NA NA 2557 FUN_000531 55 0 21 0 43 NA NA NA NA NA NA NA 2558 FUN_018790 34 0 31 0 28 NA NA NA NA NA NA NA 2559 FUN_018795 4 0 0 483 195 NA NA NA NA NA NA NA 2560 FUN_018794 0 4 0 6 4 NA NA NA NA NA NA NA 2561 FUN_018796 2321 427 1102 2931 769 NA NA NA NA NA NA NA 2562 FUN_010762 121 82 1 88 23 NA NA NA NA NA NA NA 2563 FUN_019229 21 0 21 0 30 ptg000012l:19904126-19906214 P35067 1.43e-73 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 2564 FUN_000533 3261 1986 1471 2117 2414 NA NA NA NA NA NA NA 2565 FUN_005635 0 0 2 0 12 NA NA NA NA NA NA NA 2566 FUN_005919 0 0 7 0 0 NA NA NA NA NA NA NA 2567 FUN_005918 0 0 0 0 8 NA NA NA NA NA NA NA 2568 FUN_005915 2742 1656 1128 2283 1482 ptg000001l:5646987-5692259 Q5R6J1 4.1e-31 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 2569 FUN_005915 2742 1656 1128 2283 1482 ptg000001l:5646987-5692259 Q5R6J1 3.67e-30 Sodium-dependent neutral amino acid transporter B(0)AT1 (Solute carrier family 6 member 19) (System B(0) neutral amino acid transporter AT1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0015175; GO:0015293; GO:0016324 2570 FUN_005914 40614 38228 29140 40624 26718 ptg000001l:5638538-5639656 Q86FP7 3.65e-52 40S ribosomal protein S23 Dermacentor variabilis (American dog tick) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0005791; GO:0022627; GO:0042788 2571 FUN_005914 40614 38228 29140 40624 26718 ptg000001l:5638538-5639656 Q86FP7 3.75e-26 40S ribosomal protein S23 Dermacentor variabilis (American dog tick) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003735; GO:0005791; GO:0022627; GO:0042788 2572 FUN_005917 330 9 5 127 41 NA NA NA NA NA NA NA 2573 FUN_005916 417 23 63 414 160 NA NA NA NA NA NA NA 2574 FUN_005911 136 37 48 41 146 NA NA NA NA NA NA NA 2575 FUN_005910 1224 426 542 1343 1352 NA NA NA NA NA NA NA 2576 FUN_005913 3269 1737 1702 1689 1159 ptg000001l:5627425-5637166 Q2KID6 1.62e-45 Pleiotropic regulator 1 Bos taurus (Bovine) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein localization to nucleus [GO:0034504] GO:0000398; GO:0000974; GO:0001650; GO:0005634; GO:0005662; GO:0016607; GO:0031965; GO:0034504; GO:0071007; GO:0071013; GO:1900087 2577 FUN_005912 301 191 61 142 221 NA NA NA NA NA NA NA 2578 FUN_006259 774 492 343 706 617 NA NA NA NA NA NA NA 2579 FUN_006257 0 0 0 78 22 NA NA NA NA NA NA NA 2580 FUN_006256 253 25 25 72 40 NA NA NA NA NA NA NA 2581 FUN_006255 12170 6635 5482 5948 3857 NA NA NA NA NA NA NA 2582 FUN_006254 279 411 159 349 126 NA NA NA NA NA NA NA 2583 FUN_006253 326 92 70 79 67 ptg000001l:9746650-9747256 P37235 1.1e-67 Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3) Homo sapiens (Human) NA GO:0005509; GO:0016020 2584 FUN_006252 14 35 0 56 0 NA NA NA NA NA NA NA 2585 FUN_006251 3563 2873 1866 3017 1877 ptg000001l:9731469-9737864 A5PJA8 1.56e-34 ER membrane protein complex subunit 7 Bos taurus (Bovine) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005789; GO:0016020; GO:0030246; GO:0045050; GO:0071816; GO:0072546 2586 FUN_006250 1106 555 837 879 673 ptg000001l:9729483-9731220 P0C5H0 1.63e-51 Glyoxalase domain-containing protein 5 Canis lupus familiaris (Dog) (Canis familiaris) NA NA 2587 FUN_005632 0 0 0 0 16 NA NA NA NA NA NA NA 2588 FUN_004267 57 44 23 78 101 NA NA NA NA NA NA NA 2589 FUN_043277 393 428 351 404 327 NA NA NA NA NA NA NA 2590 FUN_035655 691 404 340 447 737 ptg000025l:10365922-10372456 Q5F389 6.12e-21 WW domain-containing oxidoreductase (EC 1.1.1.-) Gallus gallus (Chicken) cellular response to transforming growth factor beta stimulus [GO:0071560]; extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of transcription by RNA polymerase II [GO:0045944]; skeletal system morphogenesis [GO:0048705]; Wnt signaling pathway [GO:0016055] GO:0001649; GO:0003713; GO:0005654; GO:0005739; GO:0005794; GO:0005829; GO:0005886; GO:0005902; GO:0016055; GO:0016491; GO:0019899; GO:0030178; GO:0045944; GO:0048705; GO:0071560; GO:0072332; GO:0090575; GO:0097191; GO:2001241 2591 FUN_035654 2555 2204 836 1686 868 ptg000025l:10352210-10360290 Q7ZWL6 9.52e-39 Repressor of RNA polymerase III transcription MAF1 homolog Xenopus laevis (African clawed frog) negative regulation of transcription by RNA polymerase III [GO:0016480] GO:0005634; GO:0005737; GO:0016480 2592 FUN_035657 252 195 27 167 79 ptg000025l:10383497-10405408 Q6PFY8 1.46e-39 Tripartite motif-containing protein 45 Mus musculus (Mouse) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 2593 FUN_035657 252 195 27 167 79 ptg000025l:10383497-10405408 Q6PFY8 9.89e-34 Tripartite motif-containing protein 45 Mus musculus (Mouse) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 2594 FUN_035656 821 529 360 728 486 NA NA NA NA NA NA NA 2595 FUN_035651 22 0 68 0 0 NA NA NA NA NA NA NA 2596 FUN_035650 0 0 67 0 0 NA NA NA NA NA NA NA 2597 FUN_035653 967 2749 1032 1733 954 NA NA NA NA NA NA NA 2598 FUN_035652 381 218 357 632 584 ptg000025l:10327601-10328627 Q80ZW0 1.87e-28 Serine/threonine-protein kinase 35 (Serine/threonine-protein kinase 35 L1) (EC 2.7.11.1) Mus musculus (Mouse) autophagy [GO:0006914]; meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006468; GO:0006914; GO:0016604; GO:0051321; GO:0106310 2599 FUN_035659 330 336 391 229 270 ptg000025l:10425859-10429185 Q6PFY8 4.28e-45 Tripartite motif-containing protein 45 Mus musculus (Mouse) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 2600 FUN_035658 273 145 323 426 428 ptg000025l:10411744-10421673 Q9NSD5 5.24e-26 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid reuptake [GO:0051936]; monocarboxylic acid transport [GO:0015718]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734]; transport across blood-brain barrier [GO:0150104] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0043005; GO:0051936; GO:0051939; GO:0070062; GO:0071705; GO:0089718; GO:0098793; GO:0150104 2601 FUN_035658 273 145 323 426 428 ptg000025l:10411744-10421673 Q9NSD5 5.24e-26 Sodium- and chloride-dependent GABA transporter 2 (GAT-2) (Solute carrier family 6 member 13) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; creatine transmembrane transport [GO:0015881]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid reuptake [GO:0051936]; monocarboxylic acid transport [GO:0015718]; nitrogen compound transport [GO:0071705]; positive regulation of necrotic cell death [GO:0010940]; sodium ion transmembrane transport [GO:0035725]; taurine transport [GO:0015734]; transport across blood-brain barrier [GO:0150104] GO:0005283; GO:0005308; GO:0005332; GO:0005368; GO:0005369; GO:0005886; GO:0008028; GO:0010940; GO:0015171; GO:0015185; GO:0015718; GO:0015734; GO:0015881; GO:0016323; GO:0035725; GO:0043005; GO:0051936; GO:0051939; GO:0070062; GO:0071705; GO:0089718; GO:0098793; GO:0150104 2602 FUN_043279 291 130 119 231 159 ptg000047l:6330675-6343052 O18276 6.98e-27 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 2603 FUN_018059 100 195 57 93 91 NA NA NA NA NA NA NA 2604 FUN_032027 99544 53362 36960 44102 11852 ptg000023l:28071635-28073548 Q60803 7.4e-72 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 2605 FUN_032026 37492 29028 25137 26715 10425 ptg000023l:28062440-28067715 Q13114 4e-70 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein 1) (LAP1) (RING-type E3 ubiquitin transferase TRAF3) Homo sapiens (Human) apoptotic process [GO:0006915]; defense response to virus [GO:0051607]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; signal transduction [GO:0007165]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; type I interferon-mediated signaling pathway [GO:0060337] GO:0000151; GO:0001817; GO:0002224; GO:0004842; GO:0005164; GO:0005739; GO:0005768; GO:0005829; GO:0006915; GO:0007165; GO:0008063; GO:0008270; GO:0009898; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0035666; GO:0042802; GO:0042981; GO:0043122; GO:0046330; GO:0050688; GO:0051607; GO:0060337; GO:0070534; GO:1902554 2606 FUN_032025 2161 796 945 1240 1695 ptg000023l:28052385-28054883 Q5U5C5 4.05e-99 U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005690; GO:0015030; GO:0016607; GO:0030622; GO:0046540; GO:0071005; GO:0071339 2607 FUN_032025 2161 796 945 1240 1695 ptg000023l:28052385-28054883 Q5U5C5 1.97e-37 U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005690; GO:0015030; GO:0016607; GO:0030622; GO:0046540; GO:0071005; GO:0071339 2608 FUN_032024 1532 1521 594 1053 725 ptg000023l:28051591-28052116 Q9VI10 1.64e-52 Probable small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2) Drosophila melanogaster (Fruit fly) mitotic cell cycle [GO:0000278]; mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000278; GO:0000387; GO:0000398; GO:0003723; GO:0005681; GO:0005682; GO:0005685; GO:0005686; GO:0005829; GO:0030532; GO:0046540; GO:0071011; GO:0071013 2609 FUN_032023 291 238 226 232 343 NA NA NA NA NA NA NA 2610 FUN_032022 1434 884 995 766 1523 NA NA NA NA NA NA NA 2611 FUN_032021 1160 900 956 666 941 NA NA NA NA NA NA NA 2612 FUN_032020 1881 1765 951 1212 1031 NA NA NA NA NA NA NA 2613 FUN_032029 49 38 34 18 16 NA NA NA NA NA NA NA 2614 FUN_032028 1487 1798 1383 1395 553 ptg000023l:28079890-28084042 Q60803 3.73e-65 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 2615 FUN_001708 0 0 14 0 6 NA NA NA NA NA NA NA 2616 FUN_001709 9 7 14 10 60 NA NA NA NA NA NA NA 2617 FUN_001707 5 0 9 7 31 NA NA NA NA NA NA NA 2618 FUN_001700 65 3 22 39 79 NA NA NA NA NA NA NA 2619 FUN_001701 1089 1327 877 546 520 NA NA NA NA NA NA NA 2620 FUN_001702 17 21 33 60 61 NA NA NA NA NA NA NA 2621 FUN_001703 0 0 0 0 6 NA NA NA NA NA NA NA 2622 FUN_043831 8 0 0 2 0 NA NA NA NA NA NA NA 2623 FUN_043832 0 7 0 6 10 NA NA NA NA NA NA NA 2624 FUN_043833 0 0 0 0 18 NA NA NA NA NA NA NA 2625 FUN_043834 4 0 1 5 16 NA NA NA NA NA NA NA 2626 FUN_043835 19629 13435 8281 14922 13147 NA NA NA NA NA NA NA 2627 FUN_043837 0 1 4 7 15 NA NA NA NA NA NA NA 2628 FUN_043838 2 2 18 4 77 NA NA NA NA NA NA NA 2629 FUN_043839 0 2 4 6 15 NA NA NA NA NA NA NA 2630 FUN_041441 186 223 67 155 160 ptg000035l:3744055-3746046 Q29R99 1.79e-42 Putative lipoyltransferase 2, mitochondrial (EC 2.3.1.181) (Lipoate-protein ligase B) (Lipoyl/octanoyl transferase) (Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of oxygen metabolic process [GO:2000376]; protein lipoylation [GO:0009249] GO:0005739; GO:0009249; GO:0016874; GO:0033819; GO:2000376 2631 FUN_005285 59 17 147 304 262 ntLink_8:33495860-33502927 Q96AY4 4.76e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2632 FUN_005285 59 17 147 304 262 ntLink_8:33495860-33502927 Q96AY4 7.99e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2633 FUN_005285 59 17 147 304 262 ntLink_8:33495860-33502927 Q96AY4 2.17e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2634 FUN_005285 59 17 147 304 262 ntLink_8:33495860-33502927 Q96AY4 6.02e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2635 FUN_005285 59 17 147 304 262 ntLink_8:33495860-33502927 Q96AY4 1.47e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2636 FUN_005285 59 17 147 304 262 ntLink_8:33495860-33502927 Q96AY4 7.99e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2637 FUN_005284 0 0 0 0 21 NA NA NA NA NA NA NA 2638 FUN_005282 44 37 149 477 333 ntLink_8:33453503-33457783 Q96AY4 4.22e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2639 FUN_005282 44 37 149 477 333 ntLink_8:33453503-33457783 Q96AY4 3.42e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2640 FUN_005282 44 37 149 477 333 ntLink_8:33453503-33457783 Q96AY4 3.33e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2641 FUN_005282 44 37 149 477 333 ntLink_8:33453503-33457783 Q96AY4 3.07e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2642 FUN_005282 44 37 149 477 333 ntLink_8:33453503-33457783 Q96AY4 1.33e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2643 FUN_005282 44 37 149 477 333 ntLink_8:33453503-33457783 Q96AY4 5.32e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2644 FUN_005289 0 0 0 15 0 NA NA NA NA NA NA NA 2645 FUN_013044 0 0 0 120 0 NA NA NA NA NA NA NA 2646 FUN_028766 148 28 9 35 18 NA NA NA NA NA NA NA 2647 FUN_028765 19 23 3 11 33 ptg000022l:3654157-3657525 Q96AY4 1.88e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2648 FUN_028765 19 23 3 11 33 ptg000022l:3654157-3657525 Q96AY4 1.66e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2649 FUN_028765 19 23 3 11 33 ptg000022l:3654157-3657525 Q96AY4 3.95e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2650 FUN_028765 19 23 3 11 33 ptg000022l:3654157-3657525 Q96AY4 2.7e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2651 FUN_028765 19 23 3 11 33 ptg000022l:3654157-3657525 Q96AY4 9.64e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2652 FUN_028765 19 23 3 11 33 ptg000022l:3654157-3657525 Q96AY4 9.36e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2653 FUN_007665 80 0 23 75 94 ptg000002l:3003142-3009031 Q7TN88 7.86e-44 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 2654 FUN_028764 115 341 270 181 74 NA NA NA NA NA NA NA 2655 FUN_007662 174 20 50 65 136 ptg000002l:2976157-2988080 Q9P0L9 3.37e-42 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) (Polycystin-2L1) (Polycystin-L) (Polycystin-L1) Homo sapiens (Human) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0009986; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0033040; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071468; GO:0071805; GO:0097730; GO:0098662 2656 FUN_028763 71 86 38 36 34 NA NA NA NA NA NA NA 2657 FUN_007669 1112 1497 517 1165 844 NA NA NA NA NA NA NA 2658 FUN_032683 88 131 0 0 118 NA NA NA NA NA NA NA 2659 FUN_032682 50 15 19 16 152 ptg000023l:34914485-34921100 Q95SX7 8.38e-35 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 2660 FUN_032681 927 450 423 618 525 ptg000023l:34888838-34898575 Q9VQX4 1.77e-25 Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21) Drosophila melanogaster (Fruit fly) NAD salvage [GO:0034355]; response to oxidative stress [GO:0006979] GO:0004516; GO:0005829; GO:0006979; GO:0016740; GO:0034355; GO:0046872 2661 FUN_032680 670 502 215 452 325 NA NA NA NA NA NA NA 2662 FUN_032687 40 129 65 648 290 NA NA NA NA NA NA NA 2663 FUN_005136 0 0 0 98 190 NA NA NA NA NA NA NA 2664 FUN_005135 457 60 257 732 483 NA NA NA NA NA NA NA 2665 FUN_032688 442 248 213 181 183 ptg000023l:34960190-34961438 Q8N4S7 1.54e-39 Progestin and adipoQ receptor family member 4 (Progestin and adipoQ receptor family member IV) Homo sapiens (Human) NA GO:0016020; GO:0038023 2666 FUN_005133 5117 3755 3147 3218 2996 ntLink_8:31416900-31424345 P29678 4.7e-22 Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1) Oryctolagus cuniculus (Rabbit) NA GO:0004674; GO:0004708; GO:0004713; GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0016020; GO:0106310 2667 FUN_005132 767 268 247 684 643 ntLink_8:31408126-31409467 Q91348 0 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2,6-P2ase) (PFK/FBPase) (6PF-2-K/Fru-2,6-P2ase liver isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] Gallus gallus (Chicken) fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose metabolic process [GO:0006000] GO:0003873; GO:0004331; GO:0005524; GO:0005829; GO:0006000; GO:0006003; GO:0043540 2668 FUN_005131 3 0 13 0 0 ntLink_8:31398241-31399378 P12256 1.37e-44 Penicillin acylase (EC 3.5.1.11) (Penicillin V amidase) (PVA) Lysinibacillus sphaericus (Bacillus sphaericus) response to antibiotic [GO:0046677] GO:0008953; GO:0046677 2669 FUN_033371 0 0 2 0 6 NA NA NA NA NA NA NA 2670 FUN_032975 3117 3088 1459 2206 764 NA NA NA NA NA NA NA 2671 FUN_032974 3651 1815 420 2650 1707 NA NA NA NA NA NA NA 2672 FUN_032977 0 12 0 52 51 NA NA NA NA NA NA NA 2673 FUN_032976 0 40 150 40 149 ptg000023l:38355551-38358454 Q96AY4 5.1e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2674 FUN_032976 0 40 150 40 149 ptg000023l:38355551-38358454 Q96AY4 3.18e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2675 FUN_032976 0 40 150 40 149 ptg000023l:38355551-38358454 Q96AY4 3.64e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2676 FUN_032976 0 40 150 40 149 ptg000023l:38355551-38358454 Q96AY4 1.55e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2677 FUN_032971 222 99 85 187 144 ptg000023l:38293163-38298784 Q8IX29 1.55e-43 F-box only protein 16 Homo sapiens (Human) NA NA 2678 FUN_032970 4146 2928 2413 3889 3111 ptg000023l:38282146-38291158 P80467 1.97e-22 Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284) Saara hardwickii (Indian spiny-tailed lizard) (Uromastyx hardwickii) ethanol oxidation [GO:0006069] GO:0004022; GO:0005737; GO:0006069; GO:0008270; GO:0106321; GO:0106322 2679 FUN_032973 2919 2812 1737 2405 1725 NA NA NA NA NA NA NA 2680 FUN_032972 210 129 187 251 226 NA NA NA NA NA NA NA 2681 FUN_032979 47 16 12 38 82 ptg000023l:38381235-38384683 Q96AY4 8.91e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2682 FUN_032979 47 16 12 38 82 ptg000023l:38381235-38384683 Q96AY4 4.1e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2683 FUN_032979 47 16 12 38 82 ptg000023l:38381235-38384683 Q96AY4 1.55e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2684 FUN_032979 47 16 12 38 82 ptg000023l:38381235-38384683 Q96AY4 1.55e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2685 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2686 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2687 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 1.22e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2688 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 8.01e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2689 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 6.99e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2690 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 4e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2691 FUN_032978 98 60 12 108 79 ptg000023l:38367390-38372572 Q96AY4 1.77e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2692 FUN_016821 0 0 22 56 0 NA NA NA NA NA NA NA 2693 FUN_016820 43 39 35 40 20 NA NA NA NA NA NA NA 2694 FUN_016822 44 26 42 55 35 NA NA NA NA NA NA NA 2695 FUN_033086 0 0 12 0 26 NA NA NA NA NA NA NA 2696 FUN_033083 48 0 38 55 251 ptg000023l:39789258-39790718 P14381 5.02e-87 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 2697 FUN_033083 48 0 38 55 251 ptg000023l:39789258-39790718 P14381 5.02e-87 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 2698 FUN_033080 0 0 7 0 0 NA NA NA NA NA NA NA 2699 FUN_006538 75 59 0 107 38 NA NA NA NA NA NA NA 2700 FUN_006539 6 34 0 66 48 NA NA NA NA NA NA NA 2701 FUN_008558 824 434 194 679 555 NA NA NA NA NA NA NA 2702 FUN_008559 1474 851 692 1273 944 ptg000002l:12903447-12906526 P48180 1.42e-47 Acetylcholine receptor subunit alpha-type acr-16 Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0042995; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1904315 2703 FUN_008556 129 242 242 317 195 NA NA NA NA NA NA NA 2704 FUN_008557 22 13 130 83 51 NA NA NA NA NA NA NA 2705 FUN_008554 1041 486 184 325 220 NA NA NA NA NA NA NA 2706 FUN_006531 717 802 221 876 653 NA NA NA NA NA NA NA 2707 FUN_008552 538 1041 461 908 260 NA NA NA NA NA NA NA 2708 FUN_008553 562 351 200 274 460 NA NA NA NA NA NA NA 2709 FUN_008550 0 0 22 0 31 NA NA NA NA NA NA NA 2710 FUN_041995 1743 1837 1041 1698 2163 ptg000035l:9651357-9665325 Q6NX31 7.02e-38 DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0003678; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162 2711 FUN_041995 1743 1837 1041 1698 2163 ptg000035l:9651357-9665325 Q6NX31 4.3e-27 DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0003678; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162 2712 FUN_041995 1743 1837 1041 1698 2163 ptg000035l:9651357-9665325 Q6NX31 1.49e-22 DNA replication licensing factor mcm7 (EC 3.6.4.12) (CDC47 homolog) (Minichromosome maintenance protein 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000785; GO:0003677; GO:0003678; GO:0005524; GO:0006268; GO:0006270; GO:0007049; GO:0016887; GO:0030174; GO:0042555; GO:0046872; GO:0071162 2713 FUN_041994 558 1530 1227 1721 1759 NA NA NA NA NA NA NA 2714 FUN_041997 106 84 89 250 94 NA NA NA NA NA NA NA 2715 FUN_041996 672 656 216 775 582 NA NA NA NA NA NA NA 2716 FUN_041991 1342 623 662 862 640 NA NA NA NA NA NA NA 2717 FUN_041990 216 128 94 293 120 NA NA NA NA NA NA NA 2718 FUN_041993 799 329 401 544 478 NA NA NA NA NA NA NA 2719 FUN_041992 481 384 184 319 304 NA NA NA NA NA NA NA 2720 FUN_016793 174 125 32 166 44 NA NA NA NA NA NA NA 2721 FUN_016792 431 48 0 90 108 NA NA NA NA NA NA NA 2722 FUN_016791 76 32 0 25 14 NA NA NA NA NA NA NA 2723 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 2.18e-49 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2724 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 9.78e-46 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2725 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 1.32e-40 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2726 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 3.33e-40 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2727 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 1.25e-33 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2728 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 1.45e-32 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2729 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 1.56e-31 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2730 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 1.73e-25 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2731 FUN_041999 5395 3336 4556 5623 6538 ptg000035l:9683070-9718447 O14715 2.19e-22 RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3) Homo sapiens (Human) NLS-bearing protein import into nucleus [GO:0006607] GO:0005643; GO:0005737; GO:0006607; GO:0031267 2732 FUN_041998 7 7 870 0 407 NA NA NA NA NA NA NA 2733 FUN_016795 475 280 227 504 269 NA NA NA NA NA NA NA 2734 FUN_016794 868 573 352 905 741 NA NA NA NA NA NA NA 2735 FUN_004668 202 128 156 206 184 NA NA NA NA NA NA NA 2736 FUN_004669 2 2 10 92 20 NA NA NA NA NA NA NA 2737 FUN_040027 52 0 0 0 27 NA NA NA NA NA NA NA 2738 FUN_040024 151 129 162 180 37 NA NA NA NA NA NA NA 2739 FUN_040023 26 0 37 33 0 NA NA NA NA NA NA NA 2740 FUN_034686 0 0 0 0 19 NA NA NA NA NA NA NA 2741 FUN_034681 7 0 9 0 24 NA NA NA NA NA NA NA 2742 FUN_034689 0 0 6 149 13 NA NA NA NA NA NA NA 2743 FUN_034688 0 0 0 0 19 NA NA NA NA NA NA NA 2744 FUN_005059 1121 482 466 1810 1089 NA NA NA NA NA NA NA 2745 FUN_032472 0 0 0 10 0 NA NA NA NA NA NA NA 2746 FUN_005056 5955 5940 3177 3326 1639 ntLink_8:30491337-30497584 P42568 3.6e-27 Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; chromatin remodeling [GO:0006338]; gene expression [GO:0010467]; hematopoietic stem cell differentiation [GO:0060218]; histone acetylation [GO:0016573]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; regulation of chromatin organization [GO:1902275]; regulation of stem cell division [GO:2000035]; regulation of transcription by RNA polymerase II [GO:0006357]; segment specification [GO:0007379] GO:0003677; GO:0003682; GO:0005634; GO:0005654; GO:0005829; GO:0006338; GO:0006357; GO:0007379; GO:0008023; GO:0009952; GO:0010467; GO:0016573; GO:0032783; GO:0035267; GO:0042393; GO:0045893; GO:0060090; GO:0060218; GO:0070062; GO:0070577; GO:0090090; GO:0140030; GO:1902275; GO:2000035; GO:2000096 2747 FUN_002543 140 0 216 524 188 NA NA NA NA NA NA NA 2748 FUN_002542 91 137 168 273 95 NA NA NA NA NA NA NA 2749 FUN_002541 47 90 0 22 24 NA NA NA NA NA NA NA 2750 FUN_002540 116 4 119 182 165 NA NA NA NA NA NA NA 2751 FUN_002546 23 65 85 400 127 NA NA NA NA NA NA NA 2752 FUN_002545 27 206 197 585 340 NA NA NA NA NA NA NA 2753 FUN_002549 39 1247 141 840 259 NA NA NA NA NA NA NA 2754 FUN_002548 16 54 32 3 19 NA NA NA NA NA NA NA 2755 FUN_012230 3 83 23 22 0 ptg000008l:6575325-6576366 P17124 1.89e-26 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 2756 FUN_012231 0 0 0 0 32 NA NA NA NA NA NA NA 2757 FUN_012232 5053 8940 2883 3296 2525 NA NA NA NA NA NA NA 2758 FUN_012233 0 9 0 0 0 NA NA NA NA NA NA NA 2759 FUN_012234 1477 1485 675 1431 2003 NA NA NA NA NA NA NA 2760 FUN_012235 2629 2115 1850 2177 1785 NA NA NA NA NA NA NA 2761 FUN_012236 545 375 231 606 393 NA NA NA NA NA NA NA 2762 FUN_012237 14036 15397 4555 13069 12245 NA NA NA NA NA NA NA 2763 FUN_012238 3162 2817 1278 4267 3011 ptg000008l:6645677-6654068 Q9H0L4 9.98e-24 Cleavage stimulation factor subunit 2 tau variant (CF-1 64 kDa subunit tau variant) (Cleavage stimulation factor 64 kDa subunit tau variant) (CSTF 64 kDa subunit tau variant) (TauCstF-64) Homo sapiens (Human) pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0003729; GO:0005654; GO:0005847; GO:0043231; GO:0098789 2764 FUN_012239 8990 4687 3826 4925 4414 NA NA NA NA NA NA NA 2765 FUN_013543 4 8 63 1 42 NA NA NA NA NA NA NA 2766 FUN_013542 108 179 122 158 257 NA NA NA NA NA NA NA 2767 FUN_013545 17 462 280 222 87 ptg000008l:23922832-23929513 P0C0R5 1.3e-40 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 2768 FUN_013547 374 590 1186 308 341 ptg000008l:23944982-23950868 Q7RTR2 4.72e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2769 FUN_013547 374 590 1186 308 341 ptg000008l:23944982-23950868 Q7RTR2 1.61e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2770 FUN_013547 374 590 1186 308 341 ptg000008l:23944982-23950868 Q7RTR2 8.17e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2771 FUN_013547 374 590 1186 308 341 ptg000008l:23944982-23950868 Q7RTR2 2.71e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 2772 FUN_013546 45 119 26 79 69 NA NA NA NA NA NA NA 2773 FUN_038267 5897 4197 4022 13120 10137 NA NA NA NA NA NA NA 2774 FUN_038266 841 1134 691 944 945 NA NA NA NA NA NA NA 2775 FUN_009630 0 0 0 329 0 NA NA NA NA NA NA NA 2776 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2777 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 1.97e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2778 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 4.08e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2779 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 3.37e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2780 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 4.42e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2781 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 4.5e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2782 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 3.05e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2783 FUN_009631 0 0 3 32 0 ptg000004l:9720036-9735096 Q96AY4 4.21e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2784 FUN_009632 27 3 9 35 0 NA NA NA NA NA NA NA 2785 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 9.66e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2786 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 9.66e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2787 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 5.39e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2788 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 5.39e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2789 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 1.56e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2790 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 1.56e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2791 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 3.47e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2792 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 3.24e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2793 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 4.29e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2794 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 8.43e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2795 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 8.64e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2796 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 8.64e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2797 FUN_009633 53 36 25 131 94 ptg000004l:9741875-9744715 Q96AY4 1.34e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2798 FUN_009636 251 182 91 32 34 NA NA NA NA NA NA NA 2799 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 1.11e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2800 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 1.15e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2801 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 1.44e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2802 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 7.39e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2803 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 2.24e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2804 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 1.51e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2805 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 1.63e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2806 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 8.82e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2807 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 1.15e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2808 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 2.37e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2809 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 7.5e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2810 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 4.89e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2811 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 3.38e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2812 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 5.8e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2813 FUN_009637 0 0 0 90 0 ptg000004l:9792345-9805336 Q96AY4 3.64e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2814 FUN_009638 3263 2595 1640 845 815 NA NA NA NA NA NA NA 2815 FUN_009639 167 113 149 59 52 ptg000004l:9830313-9836223 A0A2P1BRQ0 1.64e-81 Cytolytic toxin-alpha (Sp-CTx-alpha) Scorpaena plumieri (Spotted scorpionfish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 2816 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 6.48e-56 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2817 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 3.53e-49 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2818 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 2.76e-42 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2819 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 9.63e-35 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2820 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 3.58e-32 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2821 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 1.85e-31 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2822 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 6.29e-30 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2823 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 3.89e-29 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2824 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 7.44e-28 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2825 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 2.46e-27 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2826 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 2.92e-26 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2827 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 1.62e-25 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2828 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 1.87e-25 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2829 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 3.21e-24 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2830 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 4.56e-24 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2831 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 4.56e-24 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2832 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 5.62e-24 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2833 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 2.37e-23 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2834 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 4.34e-22 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2835 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 5.35e-22 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2836 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 2.04e-21 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2837 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 2.73e-21 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2838 FUN_029519 20349 11128 10706 23127 15826 ptg000023l:2757969-2832054 Q14204 8.59e-21 Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic) Homo sapiens (Human) cell division [GO:0051301]; cytoplasmic microtubule organization [GO:0031122]; establishment of spindle localization [GO:0051293]; microtubule-based movement [GO:0007018]; minus-end-directed vesicle transport along microtubule [GO:0072382]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; nuclear migration [GO:0007097]; P-body assembly [GO:0033962]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of intracellular transport [GO:0032388]; positive regulation of spindle assembly [GO:1905832]; regulation of metaphase plate congression [GO:0090235]; regulation of mitotic spindle organization [GO:0060236]; retrograde axonal transport [GO:0008090]; stress granule assembly [GO:0034063] GO:0000278; GO:0003723; GO:0005524; GO:0005576; GO:0005813; GO:0005829; GO:0005868; GO:0005874; GO:0005881; GO:0005938; GO:0007018; GO:0007052; GO:0007097; GO:0008090; GO:0008569; GO:0016020; GO:0030175; GO:0030286; GO:0031122; GO:0032388; GO:0033962; GO:0034063; GO:0035578; GO:0045505; GO:0051293; GO:0051301; GO:0051959; GO:0060236; GO:0070062; GO:0072382; GO:0090235; GO:0120162; GO:1904115; GO:1905832 2839 FUN_029518 2123 1332 1335 1713 1124 NA NA NA NA NA NA NA 2840 FUN_029517 359 71 92 19 38 NA NA NA NA NA NA NA 2841 FUN_012495 54 22 55 39 51 NA NA NA NA NA NA NA 2842 FUN_012496 220 111 129 150 99 NA NA NA NA NA NA NA 2843 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 1.4e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2844 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 1.37e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2845 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 8.1e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2846 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 4.96e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2847 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 4.35e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2848 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 2.11e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2849 FUN_029514 1554 166 725 686 544 ptg000023l:2666236-2673723 Q96AY4 4.21e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2850 FUN_012490 235 366 206 198 231 ptg000008l:9345996-9347328 E9PZZ1 4.18e-39 PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) Mus musculus (Mouse) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0003682; GO:0005634; GO:0010468; GO:0021979; GO:0022008; GO:0042054; GO:0046872; GO:0061629; GO:0097154 2851 FUN_012491 22 22 0 29 28 NA NA NA NA NA NA NA 2852 FUN_012492 21 50 21 20 25 NA NA NA NA NA NA NA 2853 FUN_009317 0 0 30 0 198 NA NA NA NA NA NA NA 2854 FUN_002120 37 12 8 7 26 NA NA NA NA NA NA NA 2855 FUN_010896 1537 2139 1455 1973 376 ptg000007l:4044435-4047401 Q10075 2.56e-59 Glutathione gamma-glutamylcysteinyltransferase (EC 2.3.2.15) (Phytochelatin synthase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) cellular detoxification of cadmium ion [GO:0098849]; cellular response to cadmium ion [GO:0071276]; detoxification of copper ion [GO:0010273]; phytochelatin biosynthetic process [GO:0046938] GO:0005634; GO:0005737; GO:0005829; GO:0010273; GO:0016756; GO:0046870; GO:0046938; GO:0071276; GO:0098849 2856 FUN_010897 890 688 688 973 486 NA NA NA NA NA NA NA 2857 FUN_010894 20 48 0 73 30 NA NA NA NA NA NA NA 2858 FUN_002122 28 23 26 16 28 NA NA NA NA NA NA NA 2859 FUN_010893 137 91 17 146 16 NA NA NA NA NA NA NA 2860 FUN_010890 142 197 80 125 61 NA NA NA NA NA NA NA 2861 FUN_010891 125 67 35 119 51 NA NA NA NA NA NA NA 2862 FUN_009313 457 26 30 0 217 ptg000004l:5194222-5196883 P25291 7.74e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 2863 FUN_010898 3712 3061 1867 2982 4333 NA NA NA NA NA NA NA 2864 FUN_010899 14 2 17 8 0 NA NA NA NA NA NA NA 2865 FUN_009310 1935 3227 2550 1834 935 NA NA NA NA NA NA NA 2866 FUN_042316 0 0 16 3 7 NA NA NA NA NA NA NA 2867 FUN_042317 2 0 12 7 17 NA NA NA NA NA NA NA 2868 FUN_042314 0 0 0 0 26 NA NA NA NA NA NA NA 2869 FUN_016075 20856 29132 13576 21768 13324 ptg000010l:1321795-1328988 P62262 3.75e-38 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 2870 FUN_016075 20856 29132 13576 21768 13324 ptg000010l:1321795-1328988 P62262 1.86e-24 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 2871 FUN_042312 230 72 104 0 55 NA NA NA NA NA NA NA 2872 FUN_042311 11 34 25 26 28 NA NA NA NA NA NA NA 2873 FUN_003393 12 0 0 0 20 NA NA NA NA NA NA NA 2874 FUN_003392 14 12 15 0 66 NA NA NA NA NA NA NA 2875 FUN_042318 77 127 73 127 143 ptg000036l:3688588-3700904 P14381 1.59e-89 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 2876 FUN_009098 152 0 0 0 11 NA NA NA NA NA NA NA 2877 FUN_009099 0 14 18 4 0 NA NA NA NA NA NA NA 2878 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 1.93e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2879 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 3.62e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2880 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 1.9e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2881 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 2.21e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2882 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 1.69e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2883 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 5.42e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2884 FUN_009095 19 87 40 23 25 ptg000004l:2681876-2685119 Q96AY4 4.38e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2885 FUN_009097 9 0 0 8 6 ptg000004l:2704412-2711335 Q96AY4 2.48e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2886 FUN_009097 9 0 0 8 6 ptg000004l:2704412-2711335 Q96AY4 2.48e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2887 FUN_009097 9 0 0 8 6 ptg000004l:2704412-2711335 Q96AY4 5.36e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2888 FUN_009097 9 0 0 8 6 ptg000004l:2704412-2711335 Q96AY4 4.98e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2889 FUN_009090 7 4 0 0 0 NA NA NA NA NA NA NA 2890 FUN_009091 5 15 26 1 53 NA NA NA NA NA NA NA 2891 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 4.25e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2892 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 6.93e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2893 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 5.05e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2894 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 9.59e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2895 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 9.9e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2896 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 3.39e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2897 FUN_009092 11 36 17 22 14 ptg000004l:2641508-2650184 Q96AY4 4.21e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2898 FUN_009093 0 12 21 0 0 NA NA NA NA NA NA NA 2899 FUN_016153 109 63 140 123 108 NA NA NA NA NA NA NA 2900 FUN_008941 285 220 135 379 290 NA NA NA NA NA NA NA 2901 FUN_008940 6791 6638 4052 10578 9803 ptg000004l:674967-679914 P31422 5.22e-167 Metabotropic glutamate receptor 3 (mGluR3) Rattus norvegicus (Rat) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0050804; GO:0051966; GO:0097110; GO:0097449; GO:0098794; GO:0098978; GO:0099170 2902 FUN_008943 768 599 331 460 461 NA NA NA NA NA NA NA 2903 FUN_008942 714 725 502 338 528 NA NA NA NA NA NA NA 2904 FUN_008945 23 0 32 60 79 NA NA NA NA NA NA NA 2905 FUN_008944 1188 1367 1282 1884 2137 NA NA NA NA NA NA NA 2906 FUN_008947 590 1244 373 770 131 NA NA NA NA NA NA NA 2907 FUN_008946 145 227 238 115 216 NA NA NA NA NA NA NA 2908 FUN_008949 2006 1401 2359 309 605 NA NA NA NA NA NA NA 2909 FUN_008948 102 199 30 78 24 NA NA NA NA NA NA NA 2910 FUN_026220 166 200 126 0 104 NA NA NA NA NA NA NA 2911 FUN_026221 1509 61 44 50 62 NA NA NA NA NA NA NA 2912 FUN_023616 162 248 77 132 144 ptg000017l:9966546-9971657 Q9CYL5 6.8e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 2913 FUN_026225 3197 173 149 355 87 ptg000020l:6359116-6372851 P16157 2.14e-85 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2914 FUN_026225 3197 173 149 355 87 ptg000020l:6359116-6372851 P16157 1.86e-61 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2915 FUN_026225 3197 173 149 355 87 ptg000020l:6359116-6372851 P16157 1.35e-56 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2916 FUN_026225 3197 173 149 355 87 ptg000020l:6359116-6372851 P16157 1.53e-56 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2917 FUN_026225 3197 173 149 355 87 ptg000020l:6359116-6372851 P16157 6.27e-56 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 2918 FUN_023614 4 0 0 6 1 NA NA NA NA NA NA NA 2919 FUN_026227 213 199 0 294 257 NA NA NA NA NA NA NA 2920 FUN_026228 5 8 0 29 0 NA NA NA NA NA NA NA 2921 FUN_028645 0 63 0 179 0 ptg000022l:2068990-2073536 Q96AY4 5.99e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2922 FUN_028645 0 63 0 179 0 ptg000022l:2068990-2073536 Q96AY4 1.4e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2923 FUN_028645 0 63 0 179 0 ptg000022l:2068990-2073536 Q96AY4 1.03e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2924 FUN_028645 0 63 0 179 0 ptg000022l:2068990-2073536 Q96AY4 2.51e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2925 FUN_028645 0 63 0 179 0 ptg000022l:2068990-2073536 Q96AY4 1.5e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2926 FUN_028645 0 63 0 179 0 ptg000022l:2068990-2073536 Q96AY4 3.16e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 2927 FUN_028640 0 0 0 29 0 ptg000022l:2009773-2011073 Q80XJ3 4.62e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 2928 FUN_028641 30 134 32 66 49 NA NA NA NA NA NA NA 2929 FUN_028642 0 89 30 132 78 NA NA NA NA NA NA NA 2930 FUN_028643 110 107 47 258 46 NA NA NA NA NA NA NA 2931 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 2.68e-66 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2932 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 4.41e-60 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2933 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 4.12e-58 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2934 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 1.01e-54 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2935 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 2.43e-54 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2936 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 7.19e-53 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2937 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 1.51e-52 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2938 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 1.87e-52 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2939 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 2.08e-52 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2940 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 9.71e-52 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2941 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 2.45e-51 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2942 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 1.18e-50 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2943 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 3.73e-50 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2944 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 6.47e-50 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2945 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 7.68e-49 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2946 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 2.82e-48 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2947 FUN_025751 1231 668 603 956 1597 ptg000020l:371019-375531 Q8N4W9 1.54e-23 Zinc finger protein 808 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0046872 2948 FUN_025750 12709 8976 7247 10993 6282 NA NA NA NA NA NA NA 2949 FUN_025753 1999 1550 1016 3230 3012 NA NA NA NA NA NA NA 2950 FUN_025752 8254 4373 3301 7699 6411 NA NA NA NA NA NA NA 2951 FUN_025755 6063 4544 2851 5934 4159 ptg000020l:429400-456438 A7T1N0 1.61e-25 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 2952 FUN_025755 6063 4544 2851 5934 4159 ptg000020l:429400-456438 A7T1N0 1.71e-25 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 2953 FUN_025755 6063 4544 2851 5934 4159 ptg000020l:429400-456438 A7T1N0 4.03e-24 Transient receptor potential cation channel subfamily M member-like 2 (nvTRPM2) Nematostella vectensis (Starlet sea anemone) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0046872; GO:0047631; GO:0070588; GO:0098655; GO:0099604 2954 FUN_025754 930 486 166 632 504 NA NA NA NA NA NA NA 2955 FUN_025757 1854 1658 1811 1609 2037 ptg000020l:461451-467981 Q52KV5 6.77e-23 RNA polymerase-associated protein LEO1 Xenopus laevis (African clawed frog) histone modification [GO:0016570]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0006368; GO:0016570; GO:0016593 2956 FUN_025756 808 656 735 923 963 ptg000020l:458183-461258 Q91ZS8 3.88e-79 Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase) Mus musculus (Mouse) adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; facial nerve morphogenesis [GO:0021610]; hypoglossal nerve morphogenesis [GO:0021618]; innervation [GO:0060384]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; multicellular organism growth [GO:0035264]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; neuromuscular process controlling posture [GO:0050884]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]; spinal cord ventral commissure morphogenesis [GO:0021965] GO:0003723; GO:0003725; GO:0003726; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006382; GO:0006396; GO:0006397; GO:0007274; GO:0008251; GO:0008285; GO:0016553; GO:0016556; GO:0021610; GO:0021618; GO:0021965; GO:0030336; GO:0035264; GO:0042802; GO:0044387; GO:0045070; GO:0045202; GO:0046872; GO:0050685; GO:0050884; GO:0051726; GO:0060384; GO:0060415; GO:0061744; GO:0097049 2957 FUN_025756 808 656 735 923 963 ptg000020l:458183-461258 Q91ZS8 4.51e-61 Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase) Mus musculus (Mouse) adenosine to inosine editing [GO:0006382]; base conversion or substitution editing [GO:0016553]; facial nerve morphogenesis [GO:0021610]; hypoglossal nerve morphogenesis [GO:0021618]; innervation [GO:0060384]; motor behavior [GO:0061744]; motor neuron apoptotic process [GO:0097049]; mRNA modification [GO:0016556]; mRNA processing [GO:0006397]; multicellular organism growth [GO:0035264]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; neuromuscular process controlling posture [GO:0050884]; neuromuscular synaptic transmission [GO:0007274]; positive regulation of mRNA processing [GO:0050685]; positive regulation of viral genome replication [GO:0045070]; regulation of cell cycle [GO:0051726]; RNA processing [GO:0006396]; spinal cord ventral commissure morphogenesis [GO:0021965] GO:0003723; GO:0003725; GO:0003726; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006382; GO:0006396; GO:0006397; GO:0007274; GO:0008251; GO:0008285; GO:0016553; GO:0016556; GO:0021610; GO:0021618; GO:0021965; GO:0030336; GO:0035264; GO:0042802; GO:0044387; GO:0045070; GO:0045202; GO:0046872; GO:0050685; GO:0050884; GO:0051726; GO:0060384; GO:0060415; GO:0061744; GO:0097049 2958 FUN_025759 3333 2091 1868 2739 2660 NA NA NA NA NA NA NA 2959 FUN_025758 2384 1282 875 1087 1764 ptg000020l:470211-472166 Q4V7W3 2.18e-29 Protein HEXIM1 Xenopus laevis (African clawed frog) negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0004861; GO:0005634; GO:0005737; GO:0017069 2960 FUN_017676 0 1 27 0 4 NA NA NA NA NA NA NA 2961 FUN_017675 12 0 28 0 53 NA NA NA NA NA NA NA 2962 FUN_017672 0 0 0 10 0 NA NA NA NA NA NA NA 2963 FUN_017670 4 6 4 1 4 NA NA NA NA NA NA NA 2964 FUN_017679 2 1 1 2 9 NA NA NA NA NA NA NA 2965 FUN_017678 1 0 1 3 20 NA NA NA NA NA NA NA 2966 FUN_004494 438 71 243 414 244 NA NA NA NA NA NA NA 2967 FUN_041562 5340 3572 3129 6113 4569 ptg000035l:5201084-5245691 Q93008 2.21e-21 Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X) Homo sapiens (Human) amyloid fibril formation [GO:1990000]; axon extension [GO:0048675]; BMP signaling pathway [GO:0030509]; cell division [GO:0051301]; cell migration [GO:0016477]; chromosome segregation [GO:0007059]; female gamete generation [GO:0007292]; monoubiquitinated protein deubiquitination [GO:0035520]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron migration [GO:0001764]; positive regulation of DNA demethylation [GO:1901537]; positive regulation of protein binding [GO:0032092]; positive regulation of TORC2 signaling [GO:1904515]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein K63-linked deubiquitination [GO:0070536]; protein localization [GO:0008104]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000122; GO:0001764; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0005929; GO:0007059; GO:0007179; GO:0007292; GO:0008104; GO:0008234; GO:0016020; GO:0016477; GO:0016562; GO:0016567; GO:0016579; GO:0030426; GO:0030509; GO:0032092; GO:0032435; GO:0035520; GO:0042752; GO:0048511; GO:0048675; GO:0050821; GO:0051301; GO:0061578; GO:0070410; GO:0070536; GO:0071947; GO:0101005; GO:1901537; GO:1904515; GO:1990000; GO:1990380 2968 FUN_041565 2495 1791 977 2590 1738 NA NA NA NA NA NA NA 2969 FUN_022255 44 60 34 32 246 NA NA NA NA NA NA NA 2970 FUN_022254 41 63 71 81 172 NA NA NA NA NA NA NA 2971 FUN_022257 0 25 0 9 22 NA NA NA NA NA NA NA 2972 FUN_022256 164 53 87 41 32 NA NA NA NA NA NA NA 2973 FUN_022251 0 0 0 13 26 NA NA NA NA NA NA NA 2974 FUN_022250 104 75 108 249 91 ptg000016l:6748556-6857345 P04323 3.27e-54 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 2975 FUN_022253 29 39 105 82 96 NA NA NA NA NA NA NA 2976 FUN_022252 0 16 0 4 39 NA NA NA NA NA NA NA 2977 FUN_022259 630 250 475 461 191 NA NA NA NA NA NA NA 2978 FUN_022258 121 39 32 77 57 NA NA NA NA NA NA NA 2979 FUN_011859 191 75 175 111 96 NA NA NA NA NA NA NA 2980 FUN_011851 359 379 420 338 184 ptg000008l:2108902-2110858 Q9DEB5 7.41e-179 Frizzled-10-A (Fz-10A) (Xfz10-A) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 2981 FUN_011850 17 23 23 74 34 NA NA NA NA NA NA NA 2982 FUN_011853 2049 1026 672 1383 1420 NA NA NA NA NA NA NA 2983 FUN_011855 0 32 0 27 27 NA NA NA NA NA NA NA 2984 FUN_011854 4595 3001 1215 2653 2064 ptg000008l:2137828-2139478 Q9ULV1 6.86e-180 Frizzled-4 (Fz-4) (hFz4) (FzE4) (CD antigen CD344) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to retinoic acid [GO:0071300]; cerebellum vasculature morphogenesis [GO:0061301]; extracellular matrix-cell signaling [GO:0035426]; locomotion involved in locomotory behavior [GO:0031987]; negative regulation of cell-substrate adhesion [GO:0010812]; neuron differentiation [GO:0030182]; non-canonical Wnt signaling pathway [GO:0035567]; Norrin signaling pathway [GO:0110135]; positive regulation of cell migration [GO:0030335]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron projection arborization [GO:0150012]; progesterone secretion [GO:0042701]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; retina vasculature morphogenesis in camera-type eye [GO:0061299]; retinal blood vessel morphogenesis [GO:0061304]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] GO:0001540; GO:0001570; GO:0004896; GO:0004930; GO:0005615; GO:0005886; GO:0005911; GO:0007223; GO:0007605; GO:0009986; GO:0010812; GO:0016055; GO:0017147; GO:0019955; GO:0030165; GO:0030182; GO:0030335; GO:0030425; GO:0030669; GO:0030947; GO:0031625; GO:0031987; GO:0034446; GO:0035426; GO:0035567; GO:0038023; GO:0042701; GO:0042803; GO:0042813; GO:0043507; GO:0044877; GO:0045893; GO:0046982; GO:0050775; GO:0051091; GO:0060070; GO:0061299; GO:0061301; GO:0061304; GO:0071300; GO:0098978; GO:0110135; GO:0150012; GO:1990830 2985 FUN_011857 88 23 50 11 122 NA NA NA NA NA NA NA 2986 FUN_011856 174 94 31 56 32 NA NA NA NA NA NA NA 2987 FUN_012392 196 49 154 304 238 NA NA NA NA NA NA NA 2988 FUN_024486 639 702 995 1759 1049 NA NA NA NA NA NA NA 2989 FUN_024487 112 96 31 122 97 NA NA NA NA NA NA NA 2990 FUN_024484 9767 9791 7347 8505 5779 NA NA NA NA NA NA NA 2991 FUN_024485 2522 1005 1018 1585 1681 NA NA NA NA NA NA NA 2992 FUN_024482 1997 1021 1060 3189 2089 NA NA NA NA NA NA NA 2993 FUN_024483 4008 3139 2769 5147 5337 NA NA NA NA NA NA NA 2994 FUN_024480 1332 2365 1034 1284 587 NA NA NA NA NA NA NA 2995 FUN_038194 138 1174 500 726 293 NA NA NA NA NA NA NA 2996 FUN_024488 20 0 0 29 0 NA NA NA NA NA NA NA 2997 FUN_014325 265 499 391 1416 33 NA NA NA NA NA NA NA 2998 FUN_014321 15 27 8 22 8 NA NA NA NA NA NA NA 2999 FUN_044009 184 78 0 27 28 NA NA NA NA NA NA NA 3000 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 6.05e-58 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3001 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 3.29e-51 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3002 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 1.05e-50 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3003 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 2.5e-49 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3004 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 2.6e-48 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3005 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 7.74e-48 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3006 FUN_025289 252 350 288 250 211 ptg000019l:969565-970336 Q99676 1.86e-27 Zinc finger protein 184 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008270 3007 FUN_025288 0 0 0 16 0 ptg000019l:959936-963005 Q94887 4.73e-34 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 3008 FUN_025283 55 0 23 31 19 NA NA NA NA NA NA NA 3009 FUN_025286 0 26 0 0 0 NA NA NA NA NA NA NA 3010 FUN_024158 189 219 195 229 223 NA NA NA NA NA NA NA 3011 FUN_024159 610 577 396 899 853 NA NA NA NA NA NA NA 3012 FUN_024150 454 167 239 390 1022 ptg000018l:2701668-2714182 Q3SA46 1.7e-41 T-box transcription factor TBX20 (T-box protein 20) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) positive regulation of DNA-templated transcription [GO:0045893] GO:0000978; GO:0003700; GO:0005634; GO:0045893 3013 FUN_024151 154 78 169 107 100 ptg000018l:2721836-2726903 Q9UMR3 1.11e-44 T-box transcription factor TBX20 (T-box protein 20) Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; atrioventricular valve development [GO:0003171]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac septum development [GO:0003279]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; endoderm formation [GO:0001706]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; lateral mesoderm formation [GO:0048370]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001706; GO:0001708; GO:0001947; GO:0003143; GO:0003148; GO:0003171; GO:0003175; GO:0003180; GO:0003193; GO:0003203; GO:0003207; GO:0003215; GO:0003272; GO:0003279; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0008283; GO:0009953; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0045892; GO:0048370; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0061629; GO:0097475; GO:1990837 3014 FUN_024152 678 682 391 843 430 NA NA NA NA NA NA NA 3015 FUN_024153 4687 1115 660 2827 1397 NA NA NA NA NA NA NA 3016 FUN_024154 485 128 231 323 416 NA NA NA NA NA NA NA 3017 FUN_024155 1085 508 666 1817 1639 ptg000018l:2849786-2852787 P28175 3.86e-27 Clotting factor C (FC) (EC 3.4.21.84) (Limulus factor C) [Cleaved into: Clotting factor C heavy chain; Clotting factor C light chain; Clotting factor C chain A; Clotting factor C chain B] Tachypleus tridentatus (Japanese horseshoe crab) cell adhesion [GO:0007155]; hemolymph coagulation [GO:0042381]; protein processing [GO:0016485] GO:0004252; GO:0005576; GO:0007155; GO:0016485; GO:0030246; GO:0042381 3018 FUN_024156 413 221 351 295 294 ptg000018l:2854340-2862474 O57382 2.4e-21 Tolloid-like protein 2 (EC 3.4.24.-) (Metalloprotease xolloid) (Xenopus tolloid) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004222; GO:0005509; GO:0005576; GO:0006508; GO:0008270; GO:0030154 3019 FUN_024157 3 53 38 30 24 NA NA NA NA NA NA NA 3020 FUN_035741 0 0 17 0 14 NA NA NA NA NA NA NA 3021 FUN_041574 936 670 516 627 569 NA NA NA NA NA NA NA 3022 FUN_040021 132 74 84 80 0 ptg000031l:3045349-3069097 Q8C1B2 1.29e-34 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 3023 FUN_029428 21 94 228 113 104 NA NA NA NA NA NA NA 3024 FUN_029423 2 14 10 74 0 NA NA NA NA NA NA NA 3025 FUN_029422 1500 2754 1755 2516 2281 NA NA NA NA NA NA NA 3026 FUN_029420 1163 463 280 1046 621 NA NA NA NA NA NA NA 3027 FUN_012786 1628 930 806 1046 697 NA NA NA NA NA NA NA 3028 FUN_012787 1155 1006 549 1192 1096 ptg000008l:12819771-12850329 Q9UBZ9 3.14e-24 DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase) Homo sapiens (Human) DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411] GO:0003684; GO:0003887; GO:0005654; GO:0006260; GO:0009411; GO:0017125; GO:0042276; GO:0046872; GO:0070987 3029 FUN_012787 1155 1006 549 1192 1096 ptg000008l:12819771-12850329 Q9UBZ9 2.14e-21 DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase) Homo sapiens (Human) DNA replication [GO:0006260]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; response to UV [GO:0009411] GO:0003684; GO:0003887; GO:0005654; GO:0006260; GO:0009411; GO:0017125; GO:0042276; GO:0046872; GO:0070987 3030 FUN_018315 667 138 173 372 268 NA NA NA NA NA NA NA 3031 FUN_016638 819 318 298 795 792 NA NA NA NA NA NA NA 3032 FUN_016639 1519 407 456 1406 621 ptg000011l:5697894-5702622 O15527 4.73e-58 N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (AP lyase) (EC 4.2.99.18)] Homo sapiens (Human) acute inflammatory response [GO:0002526]; aging [GO:0007568]; base-excision repair [GO:0006284]; base-excision repair, AP site formation [GO:0006285]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; depurination [GO:0045007]; depyrimidination [GO:0045008]; negative regulation of apoptotic process [GO:0043066]; negative regulation of double-strand break repair via single-strand annealing [GO:1901291]; nucleotide-excision repair, DNA incision [GO:0033683]; regulation of DNA-templated transcription [GO:0006355]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to light stimulus [GO:0009416]; response to oxidative stress [GO:0006979]; response to radiation [GO:0009314]; response to xenobiotic stimulus [GO:0009410] GO:0002526; GO:0003684; GO:0004519; GO:0005634; GO:0005654; GO:0005759; GO:0005829; GO:0006284; GO:0006285; GO:0006355; GO:0006974; GO:0006979; GO:0007568; GO:0008017; GO:0008534; GO:0009314; GO:0009410; GO:0009416; GO:0016363; GO:0016607; GO:0032355; GO:0032357; GO:0032991; GO:0033683; GO:0034039; GO:0043066; GO:0045007; GO:0045008; GO:0045471; GO:0051593; GO:0071276; GO:0140078; GO:1901291 3033 FUN_004756 8772 1060 1117 4503 1516 NA NA NA NA NA NA NA 3034 FUN_040301 3164 1634 1368 3050 4326 NA NA NA NA NA NA NA 3035 FUN_016493 8055 6472 3557 4209 3224 ptg000011l:3793053-3794033 P54357 6.72e-37 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 3036 FUN_026074 233 74 157 244 274 ptg000020l:4338456-4343922 Q7TNE1 1.89e-21 Succinate--hydroxymethylglutarate CoA-transferase (EC 2.8.3.13) (SuccinylCoA:glutarate-CoA transferase) Mus musculus (Mouse) NA GO:0005739; GO:0047369 3037 FUN_016630 0 6 0 0 2 NA NA NA NA NA NA NA 3038 FUN_026076 2004 1524 1093 2040 2347 NA NA NA NA NA NA NA 3039 FUN_004757 45 32 66 273 181 NA NA NA NA NA NA NA 3040 FUN_042911 7273 5764 3892 9903 5114 NA NA NA NA NA NA NA 3041 FUN_040300 680 803 571 842 569 NA NA NA NA NA NA NA 3042 FUN_016633 67 362 0 208 300 NA NA NA NA NA NA NA 3043 FUN_042914 192 159 87 404 324 NA NA NA NA NA NA NA 3044 FUN_026072 1073 910 826 1063 498 ptg000020l:4327773-4330295 P09601 1.14e-49 Heme oxygenase 1 (HO-1) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 1 soluble form] Homo sapiens (Human) angiogenesis [GO:0001525]; cellular iron ion homeostasis [GO:0006879]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to cisplatin [GO:0072719]; cellular response to heat [GO:0034605]; cellular response to hypoxia [GO:0071456]; cellular response to nutrient [GO:0031670]; endothelial cell proliferation [GO:0001935]; epithelial cell apoptotic process [GO:1904019]; erythrocyte homeostasis [GO:0034101]; heme catabolic process [GO:0042167]; heme oxidation [GO:0006788]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; iron ion homeostasis [GO:0055072]; liver regeneration [GO:0097421]; low-density lipoprotein particle clearance [GO:0034383]; macroautophagy [GO:0016236]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of epithelial cell apoptotic process [GO:1904036]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mast cell cytokine production [GO:0032764]; negative regulation of mast cell degranulation [GO:0043305]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:1903589]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of chemokine production [GO:0032722]; positive regulation of epithelial cell apoptotic process [GO:1904037]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of smooth muscle cell proliferation [GO:0048661]; regulation of angiogenesis [GO:0045765]; regulation of blood pressure [GO:0008217]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of transcription from RNA polymerase II promoter in response to iron [GO:0034395]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to estrogen [GO:0043627]; response to hydrogen peroxide [GO:0042542]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; small GTPase mediated signal transduction [GO:0007264]; smooth muscle hyperplasia [GO:0014806]; wound healing involved in inflammatory response [GO:0002246] GO:0001525; GO:0001935; GO:0002246; GO:0002686; GO:0004392; GO:0004630; GO:0005198; GO:0005615; GO:0005634; GO:0005654; GO:0005730; GO:0005741; GO:0005783; GO:0005789; GO:0005829; GO:0005901; GO:0006788; GO:0006879; GO:0006979; GO:0007264; GO:0008217; GO:0008630; GO:0009410; GO:0010656; GO:0014806; GO:0016020; GO:0016236; GO:0016239; GO:0016242; GO:0019899; GO:0020037; GO:0031670; GO:0032722; GO:0032764; GO:0034101; GO:0034383; GO:0034395; GO:0034605; GO:0035094; GO:0035556; GO:0042167; GO:0042542; GO:0042802; GO:0042803; GO:0043123; GO:0043305; GO:0043392; GO:0043433; GO:0043524; GO:0043619; GO:0043627; GO:0045765; GO:0045766; GO:0046872; GO:0048471; GO:0048661; GO:0048662; GO:0051090; GO:0055072; GO:0071243; GO:0071276; GO:0071456; GO:0072719; GO:0090050; GO:0097421; GO:1902042; GO:1903589; GO:1904019; GO:1904036; GO:1904037; GO:1904706 3045 FUN_016635 2070 1954 882 1177 1787 ptg000011l:5640696-5652410 P16930 8e-22 Fumarylacetoacetase (FAA) (EC 3.7.1.2) (Beta-diketonase) (Fumarylacetoacetate hydrolase) Homo sapiens (Human) arginine catabolic process [GO:0006527]; homogentisate catabolic process [GO:1902000]; L-phenylalanine catabolic process [GO:0006559]; lipid metabolic process [GO:0006629]; tyrosine catabolic process [GO:0006572] GO:0004334; GO:0005829; GO:0006527; GO:0006559; GO:0006572; GO:0006629; GO:0046872; GO:0070062; GO:1902000 3046 FUN_037419 221 70 230 462 410 NA NA NA NA NA NA NA 3047 FUN_042916 20 4 6 25 15 NA NA NA NA NA NA NA 3048 FUN_040307 748 509 458 1056 1130 NA NA NA NA NA NA NA 3049 FUN_037415 776 591 509 411 495 NA NA NA NA NA NA NA 3050 FUN_037414 3212 3509 743 5610 3815 ptg000026l:10050692-10055439 P9WKB8 5.47e-23 Putative diacyglycerol O-acyltransferase MT1809 (EC 2.3.1.20) (Putative triacylglycerol synthase MT1809) Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0006071; GO:0019432 3051 FUN_037417 1406 972 649 1314 1022 NA NA NA NA NA NA NA 3052 FUN_037416 624 240 672 563 728 ptg000026l:10067860-10073669 Q569T7 1.94e-34 Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B) Xenopus laevis (African clawed frog) carbohydrate transport [GO:0008643]; sodium ion transport [GO:0006814] GO:0006814; GO:0008643; GO:0015293; GO:0016324 3053 FUN_037411 157 0 250 188 38 NA NA NA NA NA NA NA 3054 FUN_037410 0 0 9 9 0 NA NA NA NA NA NA NA 3055 FUN_037413 5669 5097 2604 8108 5007 ptg000026l:10045966-10047442 P9WKB8 1.88e-24 Putative diacyglycerol O-acyltransferase MT1809 (EC 2.3.1.20) (Putative triacylglycerol synthase MT1809) Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0006071; GO:0019432 3056 FUN_037412 4465 3675 1135 1517 400 NA NA NA NA NA NA NA 3057 FUN_005739 134 428 145 44 27 ptg000001l:3463186-3464035 A0A1L4BJ98 3.39e-31 Dermonecrotic toxin Hl-PLD1 (EC 4.6.1.-) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Hemiscorpius lepturus (Scorpion) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 3058 FUN_005738 0 0 0 0 11 NA NA NA NA NA NA NA 3059 FUN_005730 2898 1800 1879 3258 2806 ptg000001l:3325392-3401859 P70208 4.8e-24 Plexin-A3 Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hippocampus development [GO:0021766]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; olfactory nerve formation [GO:0021628]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cytoskeleton organization [GO:0051495]; pyramidal neuron development [GO:0021860]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; trigeminal nerve structural organization [GO:0021637] GO:0002116; GO:0005886; GO:0007162; GO:0007411; GO:0008360; GO:0017154; GO:0021612; GO:0021628; GO:0021637; GO:0021766; GO:0021785; GO:0021828; GO:0021860; GO:0030334; GO:0043087; GO:0048843; GO:0048846; GO:0050772; GO:0050919; GO:0051495; GO:0097485; GO:1902287; GO:1990138 3060 FUN_005730 2898 1800 1879 3258 2806 ptg000001l:3325392-3401859 P70208 3.52e-22 Plexin-A3 Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hippocampus development [GO:0021766]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; olfactory nerve formation [GO:0021628]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cytoskeleton organization [GO:0051495]; pyramidal neuron development [GO:0021860]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; trigeminal nerve structural organization [GO:0021637] GO:0002116; GO:0005886; GO:0007162; GO:0007411; GO:0008360; GO:0017154; GO:0021612; GO:0021628; GO:0021637; GO:0021766; GO:0021785; GO:0021828; GO:0021860; GO:0030334; GO:0043087; GO:0048843; GO:0048846; GO:0050772; GO:0050919; GO:0051495; GO:0097485; GO:1902287; GO:1990138 3061 FUN_005730 2898 1800 1879 3258 2806 ptg000001l:3325392-3401859 P70208 3.52e-22 Plexin-A3 Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; branchiomotor neuron axon guidance [GO:0021785]; facial nerve structural organization [GO:0021612]; gonadotrophin-releasing hormone neuronal migration to the hypothalamus [GO:0021828]; hippocampus development [GO:0021766]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of cell adhesion [GO:0007162]; neuron projection extension [GO:1990138]; neuron projection guidance [GO:0097485]; olfactory nerve formation [GO:0021628]; positive regulation of axonogenesis [GO:0050772]; positive regulation of cytoskeleton organization [GO:0051495]; pyramidal neuron development [GO:0021860]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; trigeminal nerve structural organization [GO:0021637] GO:0002116; GO:0005886; GO:0007162; GO:0007411; GO:0008360; GO:0017154; GO:0021612; GO:0021628; GO:0021637; GO:0021766; GO:0021785; GO:0021828; GO:0021860; GO:0030334; GO:0043087; GO:0048843; GO:0048846; GO:0050772; GO:0050919; GO:0051495; GO:0097485; GO:1902287; GO:1990138 3062 FUN_005733 0 0 0 9 3 NA NA NA NA NA NA NA 3063 FUN_026078 1516 918 735 986 652 NA NA NA NA NA NA NA 3064 FUN_001429 0 71 57 18 67 ntLink_6:12382049-12387436 P58912 4.92e-77 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 3065 FUN_001429 0 71 57 18 67 ntLink_6:12382049-12387436 P58912 5.87e-45 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 3066 FUN_001428 329 582 66 170 348 ntLink_6:12376424-12377963 Q76DT2 6.46e-70 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 3067 FUN_001425 984 368 343 588 504 NA NA NA NA NA NA NA 3068 FUN_001424 1813 3150 830 1137 826 NA NA NA NA NA NA NA 3069 FUN_001427 330 519 73 198 355 ntLink_6:12365951-12367490 Q76DT2 6.46e-70 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 3070 FUN_001426 1334 626 758 1053 1231 NA NA NA NA NA NA NA 3071 FUN_001421 1978 1626 1347 2871 2968 NA NA NA NA NA NA NA 3072 FUN_001423 2418 1969 1175 2513 2224 NA NA NA NA NA NA NA 3073 FUN_001422 965 660 662 969 1060 ntLink_6:12243675-12284908 O15078 2.25e-26 Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2) Homo sapiens (Human) camera-type eye development [GO:0043010]; ciliary basal body-plasma membrane docking [GO:0097711]; ciliary transition zone assembly [GO:1905349]; cilium assembly [GO:0060271]; eye photoreceptor cell development [GO:0042462]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; non-motile cilium assembly [GO:1905515]; otic vesicle formation [GO:0030916]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201] GO:0001822; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0015031; GO:0016020; GO:0030902; GO:0030916; GO:0032391; GO:0032991; GO:0034451; GO:0035580; GO:0035869; GO:0036038; GO:0036064; GO:0042462; GO:0042802; GO:0043010; GO:0045893; GO:0048793; GO:0060271; GO:0070201; GO:0090316; GO:0097711; GO:1905349; GO:1905515 3074 FUN_001422 965 660 662 969 1060 ntLink_6:12243675-12284908 O15078 7.32e-23 Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2) Homo sapiens (Human) camera-type eye development [GO:0043010]; ciliary basal body-plasma membrane docking [GO:0097711]; ciliary transition zone assembly [GO:1905349]; cilium assembly [GO:0060271]; eye photoreceptor cell development [GO:0042462]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; non-motile cilium assembly [GO:1905515]; otic vesicle formation [GO:0030916]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; pronephros development [GO:0048793]; protein transport [GO:0015031]; regulation of establishment of protein localization [GO:0070201] GO:0001822; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0015031; GO:0016020; GO:0030902; GO:0030916; GO:0032391; GO:0032991; GO:0034451; GO:0035580; GO:0035869; GO:0036038; GO:0036064; GO:0042462; GO:0042802; GO:0043010; GO:0045893; GO:0048793; GO:0060271; GO:0070201; GO:0090316; GO:0097711; GO:1905349; GO:1905515 3075 FUN_032199 1209 518 848 1918 1425 ptg000023l:29682055-29687470 Q9PUU6 7.13e-36 Frizzled-2 (Fz-2) (Xfz2) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 3076 FUN_032199 1209 518 848 1918 1425 ptg000023l:29682055-29687470 Q9PUU6 8.72e-23 Frizzled-2 (Fz-2) (Xfz2) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 3077 FUN_004752 226 142 66 219 287 NA NA NA NA NA NA NA 3078 FUN_040305 59 42 10 54 48 NA NA NA NA NA NA NA 3079 FUN_026149 2733 2207 1758 3290 3030 NA NA NA NA NA NA NA 3080 FUN_026148 1527 1129 763 2068 1319 NA NA NA NA NA NA NA 3081 FUN_026141 931 2170 1042 1553 472 ptg000020l:5162232-5175638 Q08DY9 6.25e-31 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 3082 FUN_026140 0 165 178 331 200 NA NA NA NA NA NA NA 3083 FUN_026143 15 168 418 466 242 ptg000020l:5180208-5198088 Q92851 2.75e-25 Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; proteolysis [GO:0006508]; regulation of apoptotic process [GO:0042981] GO:0004197; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006919; GO:0031265; GO:0031625; GO:0035877; GO:0042981; GO:0043123; GO:0097153; GO:0097199; GO:0097200; GO:0097342 3084 FUN_026142 104 105 88 251 262 NA NA NA NA NA NA NA 3085 FUN_026145 2726 2923 1190 3947 3400 ptg000020l:5222972-5235700 Q9UG63 4.7e-32 ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2) Homo sapiens (Human) NA GO:0005524; GO:0016020; GO:0016887 3086 FUN_026145 2726 2923 1190 3947 3400 ptg000020l:5222972-5235700 Q9UG63 1.56e-26 ATP-binding cassette sub-family F member 2 (Iron-inhibited ABC transporter 2) Homo sapiens (Human) NA GO:0005524; GO:0016020; GO:0016887 3087 FUN_026144 774 579 569 643 789 NA NA NA NA NA NA NA 3088 FUN_026147 474 469 367 189 392 NA NA NA NA NA NA NA 3089 FUN_040304 24 37 20 93 105 ptg000031l:6738442-6742796 P22770 6.98e-40 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 3090 FUN_001395 28655 25640 21233 26865 24563 NA NA NA NA NA NA NA 3091 FUN_001394 1715 1077 502 1269 572 ntLink_6:11893139-11898927 Q2LE78 2.47e-61 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 3092 FUN_001393 88 1260 75 113 50 NA NA NA NA NA NA NA 3093 FUN_001392 1075 1301 281 576 441 NA NA NA NA NA NA NA 3094 FUN_001391 0 0 4 9 21 NA NA NA NA NA NA NA 3095 FUN_001390 70 50 17 77 51 NA NA NA NA NA NA NA 3096 FUN_001399 18 23 8 9 41 NA NA NA NA NA NA NA 3097 FUN_001398 129 48 67 91 160 NA NA NA NA NA NA NA 3098 FUN_010024 31 0 0 5 35 NA NA NA NA NA NA NA 3099 FUN_037061 11869 9996 5263 8613 4084 NA NA NA NA NA NA NA 3100 FUN_010022 20 0 0 14 24 NA NA NA NA NA NA NA 3101 FUN_040701 10 18 12 31 35 NA NA NA NA NA NA NA 3102 FUN_010020 2638 575 448 1563 1272 NA NA NA NA NA NA NA 3103 FUN_004062 711 666 313 764 404 ntLink_8:18846404-18847858 Q8WYR4 1.59e-46 Radial spoke head 1 homolog (Cancer/testis antigen 79) (CT79) (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Homo sapiens (Human) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005829; GO:0007286; GO:0031514; GO:0035082; GO:0051321; GO:0072687 3104 FUN_004063 0 0 17 15 0 NA NA NA NA NA NA NA 3105 FUN_004060 377 144 268 449 518 NA NA NA NA NA NA NA 3106 FUN_004061 341 303 387 242 396 NA NA NA NA NA NA NA 3107 FUN_004066 0 31 0 0 0 NA NA NA NA NA NA NA 3108 FUN_004067 0 0 14 0 139 NA NA NA NA NA NA NA 3109 FUN_004064 11 0 0 0 0 NA NA NA NA NA NA NA 3110 FUN_004068 20 0 0 0 48 NA NA NA NA NA NA NA 3111 FUN_004651 2051 1725 1037 1483 1137 NA NA NA NA NA NA NA 3112 FUN_006425 6788 4774 3044 6484 4446 NA NA NA NA NA NA NA 3113 FUN_031978 15 0 49 1483 146 NA NA NA NA NA NA NA 3114 FUN_004650 248 190 218 325 266 NA NA NA NA NA NA NA 3115 FUN_031970 1388 918 1094 1746 1634 NA NA NA NA NA NA NA 3116 FUN_031971 1084 1018 538 738 817 NA NA NA NA NA NA NA 3117 FUN_031972 751 633 626 689 1056 ptg000023l:27293948-27300775 C6EUD4 8.93e-33 NA NA NA NA 3118 FUN_031972 751 633 626 689 1056 ptg000023l:27293948-27300775 C6EUD4 1.6e-22 NA NA NA NA 3119 FUN_031973 647 118 159 160 384 NA NA NA NA NA NA NA 3120 FUN_031974 152 169 196 131 365 NA NA NA NA NA NA NA 3121 FUN_031975 2721 2142 1395 2856 1858 ptg000023l:27351283-27357303 Q7SX99 1.21e-69 Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] GO:0000050; GO:0000415; GO:0000821; GO:0004333; GO:0005634; GO:0005694; GO:0005739; GO:0005829; GO:0006099; GO:0006106; GO:0006108; GO:0006281; GO:0006974; GO:0045239; GO:2001034 3122 FUN_031975 2721 2142 1395 2856 1858 ptg000023l:27351283-27357303 Q7SX99 1.34e-25 Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] GO:0000050; GO:0000415; GO:0000821; GO:0004333; GO:0005634; GO:0005694; GO:0005739; GO:0005829; GO:0006099; GO:0006106; GO:0006108; GO:0006281; GO:0006974; GO:0045239; GO:2001034 3123 FUN_031975 2721 2142 1395 2856 1858 ptg000023l:27351283-27357303 Q7SX99 3.8e-24 Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] GO:0000050; GO:0000415; GO:0000821; GO:0004333; GO:0005634; GO:0005694; GO:0005739; GO:0005829; GO:0006099; GO:0006106; GO:0006108; GO:0006281; GO:0006974; GO:0045239; GO:2001034 3124 FUN_031975 2721 2142 1395 2856 1858 ptg000023l:27351283-27357303 Q7SX99 1.79e-23 Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; fumarate metabolic process [GO:0006106]; malate metabolic process [GO:0006108]; negative regulation of histone H3-K36 methylation [GO:0000415]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; regulation of arginine metabolic process [GO:0000821]; tricarboxylic acid cycle [GO:0006099]; urea cycle [GO:0000050] GO:0000050; GO:0000415; GO:0000821; GO:0004333; GO:0005634; GO:0005694; GO:0005739; GO:0005829; GO:0006099; GO:0006106; GO:0006108; GO:0006281; GO:0006974; GO:0045239; GO:2001034 3125 FUN_031976 858 661 623 818 684 NA NA NA NA NA NA NA 3126 FUN_031977 2657 2621 1523 1943 946 NA NA NA NA NA NA NA 3127 FUN_034339 1064 487 430 533 718 NA NA NA NA NA NA NA 3128 FUN_034338 2596 2189 924 2007 1595 NA NA NA NA NA NA NA 3129 FUN_034335 95 109 89 576 491 NA NA NA NA NA NA NA 3130 FUN_034334 930 839 666 576 407 NA NA NA NA NA NA NA 3131 FUN_034337 34 29 0 17 25 NA NA NA NA NA NA NA 3132 FUN_034331 240 70 50 105 93 NA NA NA NA NA NA NA 3133 FUN_034330 894 608 466 632 484 NA NA NA NA NA NA NA 3134 FUN_034333 843 468 189 233 362 ptg000024l:7779095-7783993 Q7ZWY2 1.07e-23 PIH1 domain-containing protein 1 Xenopus laevis (African clawed frog) NA GO:0005634 3135 FUN_034332 444 228 396 348 288 NA NA NA NA NA NA NA 3136 FUN_001063 1081 769 695 1011 569 NA NA NA NA NA NA NA 3137 FUN_004652 426 251 181 363 418 NA NA NA NA NA NA NA 3138 FUN_001062 134 58 55 111 61 NA NA NA NA NA NA NA 3139 FUN_004655 1529 964 124 1512 575 NA NA NA NA NA NA NA 3140 FUN_004654 443 336 0 336 103 NA NA NA NA NA NA NA 3141 FUN_043207 367 209 145 631 356 ptg000047l:5404993-5409125 Q96CU9 1.59e-24 FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) Homo sapiens (Human) mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005737; GO:0005739; GO:0005743; GO:0005747; GO:0016491; GO:0032981 3142 FUN_007004 525 303 326 427 427 NA NA NA NA NA NA NA 3143 FUN_007007 303 339 385 241 227 NA NA NA NA NA NA NA 3144 FUN_007006 1817 1523 744 1444 941 ptg000001l:19232624-19236991 Q80WQ4 9.47e-27 Probable tRNA methyltransferase 9B (Probable tRNA methyltransferase 9-like protein) (EC 2.1.1.-) Mus musculus (Mouse) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005634; GO:0005737; GO:0008175; GO:0030488; GO:0106335 3145 FUN_007001 401 265 57 319 474 NA NA NA NA NA NA NA 3146 FUN_043202 9 148 0 193 45 ptg000047l:5352132-5360513 P97402 3.5e-62 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase) Mus musculus (Mouse) maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; post-transcriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0005794; GO:0006486; GO:0007179; GO:0008109; GO:0008284; GO:0008375; GO:0010608; GO:0010718; GO:0010812; GO:0030335; GO:0034116; GO:0036438; GO:0051897; GO:0070374 3147 FUN_043201 6 0 26 8 12 NA NA NA NA NA NA NA 3148 FUN_043200 33 0 0 13 36 NA NA NA NA NA NA NA 3149 FUN_005890 1011 1060 574 898 1210 NA NA NA NA NA NA NA 3150 FUN_005891 96 0 28 25 84 NA NA NA NA NA NA NA 3151 FUN_005892 44081 47271 22169 44847 20351 NA NA NA NA NA NA NA 3152 FUN_005893 1841 1126 1378 2590 2008 NA NA NA NA NA NA NA 3153 FUN_005894 1326 775 879 1245 1710 NA NA NA NA NA NA NA 3154 FUN_007008 5581 4004 4838 4754 3073 NA NA NA NA NA NA NA 3155 FUN_043209 46 138 66 75 161 NA NA NA NA NA NA NA 3156 FUN_019074 0 16 4 0 38 NA NA NA NA NA NA NA 3157 FUN_040211 325 89 66 109 180 NA NA NA NA NA NA NA 3158 FUN_004656 1201 924 517 907 572 NA NA NA NA NA NA NA 3159 FUN_040210 2 0 0 27 7 NA NA NA NA NA NA NA 3160 FUN_040213 120 113 64 77 68 NA NA NA NA NA NA NA 3161 FUN_034803 3017 3010 2618 2693 1927 ptg000025l:306690-313221 Q4R4P4 1.68e-32 Fatty acid 2-hydroxylase (EC 1.14.18.-) (Fatty acid alpha-hydroxylase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) ceramide biosynthetic process [GO:0046513]; establishment of skin barrier [GO:0061436]; fatty acid biosynthetic process [GO:0006633]; galactosylceramide biosynthetic process [GO:0006682]; glucosylceramide biosynthetic process [GO:0006679]; plasma membrane raft organization [GO:0044857] GO:0005506; GO:0005789; GO:0006633; GO:0006679; GO:0006682; GO:0016020; GO:0020037; GO:0044857; GO:0046513; GO:0061436; GO:0080132 3162 FUN_034802 3894 5415 3296 3534 2192 NA NA NA NA NA NA NA 3163 FUN_034801 106 32 85 0 180 NA NA NA NA NA NA NA 3164 FUN_034800 59 47 30 55 44 NA NA NA NA NA NA NA 3165 FUN_034807 353 384 323 325 200 ptg000025l:333732-337674 Q08BG1 1.88e-28 Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020; GO:0016787; GO:0046872 3166 FUN_034807 353 384 323 325 200 ptg000025l:333732-337674 Q08BG1 5.9e-22 Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020; GO:0016787; GO:0046872 3167 FUN_034806 2264 1735 1433 2429 2292 NA NA NA NA NA NA NA 3168 FUN_034805 3711 2482 1807 3051 2057 ptg000025l:318271-327570 P21894 5.6e-24 Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) Bombyx mori (Silk moth) alanyl-tRNA aminoacylation [GO:0006419] GO:0000049; GO:0004813; GO:0005524; GO:0005737; GO:0006419; GO:0008270 3169 FUN_034804 867 496 285 648 335 ptg000025l:315670-317963 P36428 1.34e-28 Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) Arabidopsis thaliana (Mouse-ear cress) alanyl-tRNA aminoacylation [GO:0006419]; mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; tRNA modification [GO:0006400] GO:0000049; GO:0002161; GO:0004813; GO:0005524; GO:0005634; GO:0005739; GO:0006400; GO:0006419; GO:0008270; GO:0009507; GO:0016597; GO:0070143 3170 FUN_034804 867 496 285 648 335 ptg000025l:315670-317963 P36428 5.22e-26 Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) Arabidopsis thaliana (Mouse-ear cress) alanyl-tRNA aminoacylation [GO:0006419]; mitochondrial alanyl-tRNA aminoacylation [GO:0070143]; tRNA modification [GO:0006400] GO:0000049; GO:0002161; GO:0004813; GO:0005524; GO:0005634; GO:0005739; GO:0006400; GO:0006419; GO:0008270; GO:0009507; GO:0016597; GO:0070143 3171 FUN_034809 1943 4040 2082 1857 1599 NA NA NA NA NA NA NA 3172 FUN_034808 3620 3008 1631 2916 2413 ptg000025l:338097-347825 Q19360 6.32e-22 NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (Ectopic membrane ruffles in embryo protein 1) (Ubiquitin-activating enzyme 3 homolog) Caenorhabditis elegans negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116] GO:0005524; GO:0005634; GO:0005737; GO:0019781; GO:0032446; GO:0043518; GO:0045116 3173 FUN_034808 3620 3008 1631 2916 2413 ptg000025l:338097-347825 Q19360 6.32e-22 NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (Ectopic membrane ruffles in embryo protein 1) (Ubiquitin-activating enzyme 3 homolog) Caenorhabditis elegans negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; protein modification by small protein conjugation [GO:0032446]; protein neddylation [GO:0045116] GO:0005524; GO:0005634; GO:0005737; GO:0019781; GO:0032446; GO:0043518; GO:0045116 3174 FUN_036047 5664 4937 1771 4570 3196 NA NA NA NA NA NA NA 3175 FUN_040214 0 0 10 0 0 NA NA NA NA NA NA NA 3176 FUN_036046 737 315 289 621 837 NA NA NA NA NA NA NA 3177 FUN_036041 434 436 266 766 562 NA NA NA NA NA NA NA 3178 FUN_031012 0 0 0 9 11 NA NA NA NA NA NA NA 3179 FUN_030367 6 1 9 0 24 ptg000023l:10709822-10710585 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3180 FUN_030365 6 0 5 0 21 ptg000023l:10705770-10706533 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3181 FUN_030361 5 0 8 0 25 ptg000023l:10697666-10698429 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3182 FUN_036042 729 505 309 510 495 ptg000025l:14799301-14804233 O00750 0 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PI3K-C2-beta) (PtdIns-3-kinase C2 subunit beta) (EC 2.7.1.137) (EC 2.7.1.154) (C2-PI3K) (Phosphoinositide 3-kinase-C2-beta) Homo sapiens (Human) autophagosome organization [GO:1905037]; cell migration [GO:0016477]; cellular response to starvation [GO:0009267]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; protein kinase B signaling [GO:0043491] GO:0001727; GO:0005524; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0005886; GO:0005942; GO:0009267; GO:0014065; GO:0016020; GO:0016303; GO:0016477; GO:0030139; GO:0035005; GO:0035091; GO:0036092; GO:0043231; GO:0043491; GO:0046854; GO:0048015; GO:0052742; GO:1905037 3183 FUN_030369 6 0 7 0 23 ptg000023l:10713874-10714637 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3184 FUN_006358 1019 36 112 112 304 ptg000001l:11382159-11395060 Q8LPL3 3.83e-48 L-ascorbate oxidase (AAO) (AO) (ASO) (Ascorbase) (EC 1.10.3.3) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; L-ascorbic acid catabolic process [GO:0019854]; negative regulation of defense response to virus [GO:0050687]; negative regulation of response to salt stress [GO:1901001]; response to hydrogen peroxide [GO:0042542]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to virus [GO:0009615] GO:0005507; GO:0005576; GO:0006952; GO:0006979; GO:0008447; GO:0009536; GO:0009615; GO:0009651; GO:0016491; GO:0019854; GO:0042542; GO:0050687; GO:1901001 3185 FUN_006359 70 0 0 0 15 ptg000001l:11408112-11419063 S8FIE4 4.82e-41 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 3186 FUN_006352 0 7 0 0 11 NA NA NA NA NA NA NA 3187 FUN_006350 4 156 101 0 152 NA NA NA NA NA NA NA 3188 FUN_006351 0 0 0 6 2 NA NA NA NA NA NA NA 3189 FUN_006357 128 10 36 71 71 NA NA NA NA NA NA NA 3190 FUN_042157 45 9 9 0 33 NA NA NA NA NA NA NA 3191 FUN_042150 30 128 0 0 217 NA NA NA NA NA NA NA 3192 FUN_042152 8 8 13 0 19 NA NA NA NA NA NA NA 3193 FUN_012153 731 457 506 553 559 NA NA NA NA NA NA NA 3194 FUN_042158 26 31 16 12 35 NA NA NA NA NA NA NA 3195 FUN_042159 1 2 9 0 1 NA NA NA NA NA NA NA 3196 FUN_037319 166 57 72 210 133 ptg000026l:8674585-8675599 P07550 1.16e-26 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Homo sapiens (Human) activation of adenylate cyclase activity [GO:0007190]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; adrenergic receptor signaling pathway [GO:0071875]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; endosome to lysosome transport [GO:0008333]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cAMP-dependent protein kinase activity [GO:2000481]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; response to psychosocial stress [GO:1990911]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005764; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007166; GO:0007171; GO:0007188; GO:0007190; GO:0008179; GO:0008333; GO:0009409; GO:0010008; GO:0010739; GO:0015459; GO:0016020; GO:0016324; GO:0030501; GO:0030669; GO:0031649; GO:0040015; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071875; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1990911; GO:2000481; GO:2000969 3197 FUN_013369 1232 1256 1370 886 766 NA NA NA NA NA NA NA 3198 FUN_004853 958 683 508 1031 751 ntLink_8:27875126-27881616 Q6ZQ11 1.58e-112 Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] GO:0002063; GO:0005576; GO:0005794; GO:0008376; GO:0009954; GO:0016757; GO:0030206; GO:0030279; GO:0031667; GO:0032580; GO:0045880; GO:0046872; GO:0047238; GO:0050510; GO:0051216; GO:0051923; GO:0060349 3199 FUN_004853 958 683 508 1031 751 ntLink_8:27875126-27881616 Q6ZQ11 3.36e-74 Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) Mus musculus (Mouse) bone morphogenesis [GO:0060349]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; negative regulation of ossification [GO:0030279]; positive regulation of smoothened signaling pathway [GO:0045880]; proximal/distal pattern formation [GO:0009954]; response to nutrient levels [GO:0031667]; sulfation [GO:0051923] GO:0002063; GO:0005576; GO:0005794; GO:0008376; GO:0009954; GO:0016757; GO:0030206; GO:0030279; GO:0031667; GO:0032580; GO:0045880; GO:0046872; GO:0047238; GO:0050510; GO:0051216; GO:0051923; GO:0060349 3200 FUN_003800 34 42 13 108 118 NA NA NA NA NA NA NA 3201 FUN_004851 7827 5047 4168 8014 4767 NA NA NA NA NA NA NA 3202 FUN_004850 11 1 64 38 109 NA NA NA NA NA NA NA 3203 FUN_004856 677 595 291 209 113 NA NA NA NA NA NA NA 3204 FUN_003806 8 0 0 0 0 ntLink_8:15611524-15613517 O70165 1.19e-41 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 3205 FUN_003809 0 0 0 16 0 NA NA NA NA NA NA NA 3206 FUN_004859 467 1036 840 758 222 NA NA NA NA NA NA NA 3207 FUN_040790 0 22 0 0 9 NA NA NA NA NA NA NA 3208 FUN_037758 694 3058 2446 581 953 NA NA NA NA NA NA NA 3209 FUN_037759 102 105 160 56 93 NA NA NA NA NA NA NA 3210 FUN_040795 0 0 0 0 26 NA NA NA NA NA NA NA 3211 FUN_040796 0 0 0 0 31 NA NA NA NA NA NA NA 3212 FUN_037752 848 756 513 793 615 NA NA NA NA NA NA NA 3213 FUN_037753 123 59 33 60 64 NA NA NA NA NA NA NA 3214 FUN_037750 1125 567 417 810 1040 NA NA NA NA NA NA NA 3215 FUN_037751 4458 3653 3079 3128 1722 NA NA NA NA NA NA NA 3216 FUN_037756 2320 2453 905 2117 978 NA NA NA NA NA NA NA 3217 FUN_037757 563 183 174 133 249 NA NA NA NA NA NA NA 3218 FUN_037754 569 913 528 550 391 NA NA NA NA NA NA NA 3219 FUN_037755 312 204 184 293 291 ptg000026l:13161761-13164443 Q3ZCK5 5.51e-54 Cyclin-C Bos taurus (Bovine) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016538; GO:0016592; GO:0045944 3220 FUN_037755 312 204 184 293 291 ptg000026l:13161761-13164443 Q3ZCK5 1.89e-48 Cyclin-C Bos taurus (Bovine) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0006357; GO:0016538; GO:0016592; GO:0045944 3221 FUN_012807 0 16 0 0 0 NA NA NA NA NA NA NA 3222 FUN_012805 0 0 6 0 7 NA NA NA NA NA NA NA 3223 FUN_035502 1631 764 463 998 482 NA NA NA NA NA NA NA 3224 FUN_012803 0 0 0 26 0 NA NA NA NA NA NA NA 3225 FUN_012802 28 0 24 0 3 NA NA NA NA NA NA NA 3226 FUN_012801 6292 2403 2416 6022 3617 NA NA NA NA NA NA NA 3227 FUN_035505 0 0 16 20 58 NA NA NA NA NA NA NA 3228 FUN_012809 0 0 0 0 46 NA NA NA NA NA NA NA 3229 FUN_012808 0 14 0 0 0 NA NA NA NA NA NA NA 3230 FUN_032245 2131 1412 980 1749 1535 ptg000023l:30125027-30137415 P92208 1.53e-30 Stress-activated protein kinase JNK (dJNK) (EC 2.7.11.24) (Protein basket) Drosophila melanogaster (Fruit fly) antibacterial humoral response [GO:0019731]; axon extension [GO:0048675]; axon guidance [GO:0007411]; cellular response to arsenic-containing substance [GO:0071243]; cellular response to cadmium ion [GO:0071276]; cellular response to oxidative stress [GO:0034599]; cellular response to reactive oxygen species [GO:0034614]; chorion micropyle formation [GO:0046844]; collateral sprouting of injured axon [GO:0048674]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; engulfment of apoptotic cell [GO:0043652]; follicle cell of egg chamber development [GO:0030707]; imaginal disc fusion, thorax closure [GO:0046529]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; JUN phosphorylation [GO:0007258]; long-term memory [GO:0007616]; melanization defense response [GO:0035006]; mushroom body development [GO:0016319]; neuron development [GO:0048666]; neuron projection morphogenesis [GO:0048812]; peptidoglycan recognition protein signaling pathway [GO:0061057]; positive regulation of autophagy [GO:0010508]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of cell death [GO:0010942]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron remodeling [GO:1904801]; response to heat [GO:0009408]; response to oxidative stress [GO:0006979]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; wound healing [GO:0042060]; wound healing, spreading of epidermal cells [GO:0035313] GO:0004672; GO:0004674; GO:0004705; GO:0004707; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006979; GO:0007254; GO:0007258; GO:0007391; GO:0007395; GO:0007411; GO:0007616; GO:0009408; GO:0010508; GO:0010628; GO:0010942; GO:0016319; GO:0019731; GO:0030424; GO:0030425; GO:0030707; GO:0033209; GO:0034599; GO:0034614; GO:0035006; GO:0035313; GO:0035556; GO:0042060; GO:0043652; GO:0046529; GO:0046843; GO:0046844; GO:0048010; GO:0048615; GO:0048666; GO:0048674; GO:0048675; GO:0048803; GO:0048812; GO:0061057; GO:0071243; GO:0071276; GO:0071907; GO:0106310; GO:1903688; GO:1904801 3231 FUN_032244 3483 1230 1404 2720 2502 NA NA NA NA NA NA NA 3232 FUN_032249 360 283 227 241 279 ptg000023l:30216528-30223626 Q4H4B6 6.41e-29 Protein scribble homolog (Scribble1) Danio rerio (Zebrafish) (Brachydanio rerio) activation of GTPase activity [GO:0090630]; anterior/posterior axon guidance [GO:0033564]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; commissural neuron axon guidance [GO:0071679]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube formation [GO:0001841]; neuromast development [GO:0048884]; neuron migration [GO:0001764]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; vasculature development [GO:0001944] GO:0000132; GO:0001736; GO:0001764; GO:0001841; GO:0001944; GO:0005737; GO:0005886; GO:0005911; GO:0005912; GO:0008283; GO:0014069; GO:0016020; GO:0016323; GO:0016477; GO:0030027; GO:0030054; GO:0033564; GO:0035089; GO:0043065; GO:0043113; GO:0045197; GO:0045930; GO:0046982; GO:0048884; GO:0050918; GO:0060027; GO:0060561; GO:0071679; GO:0090630; GO:0097120; GO:0097475; GO:0098609; GO:0098793; GO:0098887; GO:0098968 3233 FUN_032249 360 283 227 241 279 ptg000023l:30216528-30223626 Q4H4B6 6.41e-29 Protein scribble homolog (Scribble1) Danio rerio (Zebrafish) (Brachydanio rerio) activation of GTPase activity [GO:0090630]; anterior/posterior axon guidance [GO:0033564]; apoptotic process involved in morphogenesis [GO:0060561]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; commissural neuron axon guidance [GO:0071679]; convergent extension involved in gastrulation [GO:0060027]; establishment of apical/basal cell polarity [GO:0035089]; establishment of mitotic spindle orientation [GO:0000132]; establishment of planar polarity [GO:0001736]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; motor neuron migration [GO:0097475]; negative regulation of mitotic cell cycle [GO:0045930]; neural tube formation [GO:0001841]; neuromast development [GO:0048884]; neuron migration [GO:0001764]; neurotransmitter receptor transport postsynaptic membrane to endosome [GO:0098968]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive chemotaxis [GO:0050918]; positive regulation of apoptotic process [GO:0043065]; receptor clustering [GO:0043113]; receptor localization to synapse [GO:0097120]; vasculature development [GO:0001944] GO:0000132; GO:0001736; GO:0001764; GO:0001841; GO:0001944; GO:0005737; GO:0005886; GO:0005911; GO:0005912; GO:0008283; GO:0014069; GO:0016020; GO:0016323; GO:0016477; GO:0030027; GO:0030054; GO:0033564; GO:0035089; GO:0043065; GO:0043113; GO:0045197; GO:0045930; GO:0046982; GO:0048884; GO:0050918; GO:0060027; GO:0060561; GO:0071679; GO:0090630; GO:0097120; GO:0097475; GO:0098609; GO:0098793; GO:0098887; GO:0098968 3234 FUN_032248 8038 5334 4071 6532 5292 NA NA NA NA NA NA NA 3235 FUN_008295 987 1053 717 1155 690 NA NA NA NA NA NA NA 3236 FUN_008294 2488 1385 890 1432 969 NA NA NA NA NA NA NA 3237 FUN_005079 77 573 306 1343 157 ntLink_8:30903628-30905725 Q95P04 4.57e-41 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 3238 FUN_008291 1408 868 575 813 726 NA NA NA NA NA NA NA 3239 FUN_008290 2626 2229 1477 3024 2390 NA NA NA NA NA NA NA 3240 FUN_008293 5676 5683 2025 2557 3180 NA NA NA NA NA NA NA 3241 FUN_008292 1331 1594 936 857 1115 NA NA NA NA NA NA NA 3242 FUN_005072 644 164 121 638 264 NA NA NA NA NA NA NA 3243 FUN_005073 12 154 215 322 0 NA NA NA NA NA NA NA 3244 FUN_008299 234 255 82 109 295 NA NA NA NA NA NA NA 3245 FUN_005074 383 1493 793 2649 313 ntLink_8:30880789-30884454 Q95P04 1.89e-40 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 3246 FUN_005074 383 1493 793 2649 313 ntLink_8:30880789-30884454 Q95P04 9.47e-40 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 3247 FUN_005075 623 1790 1471 5124 603 ntLink_8:30889344-30897092 Q95P04 2.37e-40 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 3248 FUN_005075 623 1790 1471 5124 603 ntLink_8:30889344-30897092 Q95P04 4.48e-39 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 3249 FUN_002868 350 53 179 98 202 ntLink_8:7143332-7159431 P0C6B8 2.09e-22 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 3250 FUN_002869 1203 506 209 940 1334 NA NA NA NA NA NA NA 3251 FUN_002860 27 1 17 9 89 NA NA NA NA NA NA NA 3252 FUN_002861 1189 1199 429 874 292 ntLink_8:7079127-7082508 Q96AY4 7.8e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3253 FUN_002861 1189 1199 429 874 292 ntLink_8:7079127-7082508 Q96AY4 2.87e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3254 FUN_002861 1189 1199 429 874 292 ntLink_8:7079127-7082508 Q96AY4 9.24e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3255 FUN_002861 1189 1199 429 874 292 ntLink_8:7079127-7082508 Q96AY4 4.67e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3256 FUN_002861 1189 1199 429 874 292 ntLink_8:7079127-7082508 Q96AY4 1.12e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3257 FUN_002861 1189 1199 429 874 292 ntLink_8:7079127-7082508 Q96AY4 2.05e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3258 FUN_002863 2 0 0 6 11 ntLink_8:7088891-7097128 P14381 4.47e-103 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 3259 FUN_002863 2 0 0 6 11 ntLink_8:7088891-7097128 P14381 4.47e-103 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 3260 FUN_002865 354 522 99 245 234 NA NA NA NA NA NA NA 3261 FUN_002866 53 0 20 7 208 NA NA NA NA NA NA NA 3262 FUN_008749 1579 2432 1156 2304 1180 NA NA NA NA NA NA NA 3263 FUN_008748 148 32 88 41 102 NA NA NA NA NA NA NA 3264 FUN_008747 737 76 74 416 200 NA NA NA NA NA NA NA 3265 FUN_008746 20 11 11 53 76 NA NA NA NA NA NA NA 3266 FUN_008745 157 115 171 145 145 NA NA NA NA NA NA NA 3267 FUN_008744 269 39 67 422 611 NA NA NA NA NA NA NA 3268 FUN_008743 1550 506 0 492 820 NA NA NA NA NA NA NA 3269 FUN_008742 490 390 209 403 241 NA NA NA NA NA NA NA 3270 FUN_008741 1498 482 512 1309 815 NA NA NA NA NA NA NA 3271 FUN_008740 364 354 311 264 184 NA NA NA NA NA NA NA 3272 FUN_000592 1363 2531 1061 1536 2321 NA NA NA NA NA NA NA 3273 FUN_000593 3611 4250 2365 3712 3424 NA NA NA NA NA NA NA 3274 FUN_000590 17 0 2 2 32 NA NA NA NA NA NA NA 3275 FUN_000591 3304 3950 2304 6216 2319 NA NA NA NA NA NA NA 3276 FUN_000596 2751 2190 2125 2780 2234 NA NA NA NA NA NA NA 3277 FUN_000597 34 17 0 0 20 NA NA NA NA NA NA NA 3278 FUN_041548 5577 5229 2631 4672 4057 NA NA NA NA NA NA NA 3279 FUN_000595 196 188 107 176 131 NA NA NA NA NA NA NA 3280 FUN_041546 3863 2003 2087 3331 2104 ptg000035l:5030630-5038209 P31400 3.68e-69 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 3281 FUN_041546 3863 2003 2087 3331 2104 ptg000035l:5030630-5038209 P31400 3.68e-69 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 3282 FUN_041546 3863 2003 2087 3331 2104 ptg000035l:5030630-5038209 P31400 3.68e-69 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 3283 FUN_041546 3863 2003 2087 3331 2104 ptg000035l:5030630-5038209 P31400 1.01e-38 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 3284 FUN_041546 3863 2003 2087 3331 2104 ptg000035l:5030630-5038209 P31400 1.01e-28 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 3285 FUN_041546 3863 2003 2087 3331 2104 ptg000035l:5030630-5038209 P31400 8.58e-24 V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar proton pump subunit alpha) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0005524; GO:0033180; GO:0046933; GO:0046961 3286 FUN_041547 1184 1256 553 920 561 NA NA NA NA NA NA NA 3287 FUN_000598 13 25 12 18 23 NA NA NA NA NA NA NA 3288 FUN_041545 1536 1136 686 1493 1194 NA NA NA NA NA NA NA 3289 FUN_041542 96 7 36 7 25 ptg000035l:4954012-4956280 G5EDU6 2.66e-45 Transcription factor ovo-like homolog lin-48 (Abnormal cell lineage protein 48) Caenorhabditis elegans epidermal cell differentiation [GO:0009913]; hindgut morphogenesis [GO:0007442]; nematode male tail tip morphogenesis [GO:0045138]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007442; GO:0009913; GO:0045138; GO:0046872 3290 FUN_041543 35 38 14 42 40 NA NA NA NA NA NA NA 3291 FUN_041540 34 94 64 89 40 ptg000035l:4933515-4939123 G5EDU6 1.06e-46 Transcription factor ovo-like homolog lin-48 (Abnormal cell lineage protein 48) Caenorhabditis elegans epidermal cell differentiation [GO:0009913]; hindgut morphogenesis [GO:0007442]; nematode male tail tip morphogenesis [GO:0045138]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007442; GO:0009913; GO:0045138; GO:0046872 3292 FUN_033125 133 243 57 231 122 NA NA NA NA NA NA NA 3293 FUN_033127 527 275 222 229 200 ptg000023l:40242652-40252448 Q5HYA8 3.05e-60 Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67) Homo sapiens (Human) cilium assembly [GO:0060271]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005789; GO:0005813; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035869; GO:0036038; GO:0051082; GO:0060170; GO:0060271 3294 FUN_033127 527 275 222 229 200 ptg000023l:40242652-40252448 Q5HYA8 3.28e-54 Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67) Homo sapiens (Human) cilium assembly [GO:0060271]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005789; GO:0005813; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035869; GO:0036038; GO:0051082; GO:0060170; GO:0060271 3295 FUN_033127 527 275 222 229 200 ptg000023l:40242652-40252448 Q5HYA8 1.85e-32 Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67) Homo sapiens (Human) cilium assembly [GO:0060271]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005789; GO:0005813; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035869; GO:0036038; GO:0051082; GO:0060170; GO:0060271 3296 FUN_033126 3670 2688 1964 2385 2761 ptg000023l:40208181-40242387 Q9NBX4 3.67e-32 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 3297 FUN_033121 24 6 12 18 18 NA NA NA NA NA NA NA 3298 FUN_033120 4374 8818 4733 8817 7622 ptg000023l:40151242-40162167 Q3M6C3 9.12e-35 Demethyl-4-deoxygadusol synthase (DDGS) (EC 4.2.3.154) Trichormus variabilis (strain ATCC 29413 / PCC 7937) (Anabaena variabilis) antibiotic biosynthetic process [GO:0017000] GO:0000166; GO:0016829; GO:0017000; GO:0046872 3299 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 3.35e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3300 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 3.84e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3301 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 9.89e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3302 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 3.36e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3303 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 8.33e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3304 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 2.1e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3305 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 2.63e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3306 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 1.41e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3307 FUN_033123 605 112 582 1904 1188 ptg000023l:40183780-40190009 Q96AY4 4.76e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3308 FUN_033122 26 0 45 50 21 NA NA NA NA NA NA NA 3309 FUN_033129 42 103 71 112 128 NA NA NA NA NA NA NA 3310 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 4.22e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3311 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 1.4e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3312 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 1.27e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3313 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 1.01e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3314 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 2.69e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3315 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 6.18e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3316 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 8.06e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3317 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 1.66e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3318 FUN_033128 3 79 0 106 38 ptg000023l:40260280-40262718 Q96AY4 2.74e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3319 FUN_016616 4311 3578 1241 3199 1947 NA NA NA NA NA NA NA 3320 FUN_016617 15 17 35 0 23 NA NA NA NA NA NA NA 3321 FUN_016614 361 320 101 254 285 ptg000011l:5391222-5400827 P52483 3.92e-21 Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcM2) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3) Mus musculus (Mouse) protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0005737; GO:0061631; GO:0070534; GO:0070936; GO:0070979 3322 FUN_042935 0 0 14 0 62 NA NA NA NA NA NA NA 3323 FUN_042932 1127 797 479 11 1126 NA NA NA NA NA NA NA 3324 FUN_016613 15 22 0 0 0 NA NA NA NA NA NA NA 3325 FUN_016610 488 249 233 436 246 NA NA NA NA NA NA NA 3326 FUN_042931 7 2 4 0 3 NA NA NA NA NA NA NA 3327 FUN_042938 149 94 101 13 193 NA NA NA NA NA NA NA 3328 FUN_042939 66 250 243 0 349 NA NA NA NA NA NA NA 3329 FUN_032412 16 436 147 350 179 ptg000023l:31679732-31681040 Q6DIV6 1.11e-47 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 3330 FUN_013323 418 231 315 429 224 NA NA NA NA NA NA NA 3331 FUN_010515 125 84 70 164 290 NA NA NA NA NA NA NA 3332 FUN_010512 321 551 296 237 345 NA NA NA NA NA NA NA 3333 FUN_034478 2350 1686 1275 1258 1399 NA NA NA NA NA NA NA 3334 FUN_034479 3694 2504 1974 2295 2318 NA NA NA NA NA NA NA 3335 FUN_034473 2 0 2 0 6 NA NA NA NA NA NA NA 3336 FUN_034477 84 88 168 129 276 ptg000024l:9132776-9173468 P21328 1.45e-28 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 3337 FUN_034474 0 0 6 0 3 NA NA NA NA NA NA NA 3338 FUN_028481 728 378 342 585 624 NA NA NA NA NA NA NA 3339 FUN_028485 3651 4139 1459 4454 2393 NA NA NA NA NA NA NA 3340 FUN_011648 0 0 18 10 4 NA NA NA NA NA NA NA 3341 FUN_011645 2 0 0 5 11 NA NA NA NA NA NA NA 3342 FUN_011646 6 2 9 0 23 NA NA NA NA NA NA NA 3343 FUN_011647 10 0 22 1 53 NA NA NA NA NA NA NA 3344 FUN_028488 728 343 273 471 370 NA NA NA NA NA NA NA 3345 FUN_028489 641 418 349 658 417 NA NA NA NA NA NA NA 3346 FUN_014504 12103 6827 5542 12198 11173 ptg000009l:709588-745074 Q6ZRS2 2.31e-69 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 3347 FUN_014504 12103 6827 5542 12198 11173 ptg000009l:709588-745074 Q6ZRS2 2.31e-69 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 3348 FUN_014504 12103 6827 5542 12198 11173 ptg000009l:709588-745074 Q6ZRS2 2.6e-54 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 3349 FUN_014504 12103 6827 5542 12198 11173 ptg000009l:709588-745074 Q6ZRS2 9.89e-43 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 3350 FUN_014504 12103 6827 5542 12198 11173 ptg000009l:709588-745074 Q6ZRS2 1.03e-23 Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000786; GO:0000812; GO:0003677; GO:0003713; GO:0004386; GO:0004402; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0006355; GO:0006357; GO:0016604; GO:0016887; GO:0032991; GO:0042393; GO:0048471; GO:0140658 3351 FUN_014506 586 284 352 575 779 NA NA NA NA NA NA NA 3352 FUN_013732 0 0 37 0 86 NA NA NA NA NA NA NA 3353 FUN_014501 299 153 72 373 290 NA NA NA NA NA NA NA 3354 FUN_014502 536 322 162 436 427 NA NA NA NA NA NA NA 3355 FUN_014508 0 0 6 16 9 NA NA NA NA NA NA NA 3356 FUN_014509 7045 9093 4464 9850 7706 NA NA NA NA NA NA NA 3357 FUN_013739 0 0 7 0 0 NA NA NA NA NA NA NA 3358 FUN_029498 29 0 56 0 87 NA NA NA NA NA NA NA 3359 FUN_029499 0 0 25 0 40 NA NA NA NA NA NA NA 3360 FUN_029494 31 0 0 0 0 NA NA NA NA NA NA NA 3361 FUN_029495 40 0 0 36 62 NA NA NA NA NA NA NA 3362 FUN_000080 0 0 0 0 6 ntLink_4:79774-80969 P35061 7.49e-82 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3363 FUN_026389 1244 958 439 695 566 NA NA NA NA NA NA NA 3364 FUN_026388 9218 10428 8860 7222 3586 NA NA NA NA NA NA NA 3365 FUN_026385 3958 3281 2616 6085 4377 ptg000020l:8237176-8241309 Q9DBP0 1.87e-121 Sodium-dependent phosphate transport protein 2B (Sodium-phosphate transport protein 2B) (Na(+)-dependent phosphate cotransporter 2B) (Sodium/phosphate cotransporter 2B) (Na(+)/Pi cotransporter 2B) (NaPi-2b) (Solute carrier family 34 member 2) Mus musculus (Mouse) cellular phosphate ion homeostasis [GO:0030643]; in utero embryonic development [GO:0001701]; phosphate ion transport [GO:0006817]; response to estrogen [GO:0043627]; sodium-dependent phosphate transport [GO:0044341] GO:0001701; GO:0005436; GO:0005903; GO:0006817; GO:0016020; GO:0016324; GO:0019904; GO:0030643; GO:0031402; GO:0031526; GO:0031528; GO:0031982; GO:0042301; GO:0043627; GO:0044341 3366 FUN_026380 451 241 169 425 266 NA NA NA NA NA NA NA 3367 FUN_022862 1715 1273 530 1103 1250 NA NA NA NA NA NA NA 3368 FUN_022863 968 782 619 666 1890 NA NA NA NA NA NA NA 3369 FUN_022860 8349 6249 4094 9661 6261 NA NA NA NA NA NA NA 3370 FUN_022861 6397 4487 2193 3462 1653 NA NA NA NA NA NA NA 3371 FUN_022866 1565 1350 806 1084 1302 NA NA NA NA NA NA NA 3372 FUN_022867 98 883 325 108 53 NA NA NA NA NA NA NA 3373 FUN_022864 1019 897 547 792 351 NA NA NA NA NA NA NA 3374 FUN_022865 635 618 295 476 411 ptg000017l:820976-825471 Q80UY2 6.76e-25 E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (Differentially expressed in branching tubulogenesis 91) (Debt-91) (RING-type E3 ubiquitin transferase KCMF1) Mus musculus (Mouse) protein ubiquitination [GO:0016567]; synaptic signaling [GO:0099536] GO:0005829; GO:0005886; GO:0008270; GO:0016567; GO:0045202; GO:0061630; GO:0099536 3375 FUN_022868 683 373 311 229 317 ptg000017l:849381-850383 Q804R0 1.09e-28 Transcription factor LBX2 (Ladybird homeobox 2) (Ladybird homeobox protein homolog 2) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic axis specification [GO:0000578]; muscle cell development [GO:0055001]; muscle cell differentiation [GO:0042692]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; posterior lateral line neuromast deposition [GO:0048922]; posterior lateral line neuromast primordium migration [GO:0048920]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000578; GO:0000981; GO:0005634; GO:0006357; GO:0042692; GO:0048920; GO:0048922; GO:0055001; GO:0060828; GO:1904105; GO:1990837; GO:2000052 3376 FUN_022869 3423 1379 1357 1976 1313 NA NA NA NA NA NA NA 3377 FUN_029728 12 13 12 16 13 NA NA NA NA NA NA NA 3378 FUN_029729 47 8 6 21 42 NA NA NA NA NA NA NA 3379 FUN_029724 0 34 0 0 30 NA NA NA NA NA NA NA 3380 FUN_029725 1661 1405 440 1456 1552 NA NA NA NA NA NA NA 3381 FUN_029726 0 0 8 0 0 ptg000023l:5038404-5040518 P10978 2.41e-38 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 3382 FUN_029727 304 479 321 484 180 NA NA NA NA NA NA NA 3383 FUN_029720 241 133 275 1108 122 NA NA NA NA NA NA NA 3384 FUN_029721 168 0 33 65 0 NA NA NA NA NA NA NA 3385 FUN_029722 375 0 74 256 31 NA NA NA NA NA NA NA 3386 FUN_029723 1579 229 388 1511 186 NA NA NA NA NA NA NA 3387 FUN_023403 976 611 286 864 516 ptg000017l:7171736-7192592 Q9CR35 3.23e-39 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Mus musculus (Mouse) digestion [GO:0007586]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to cytokine [GO:0034097] GO:0004252; GO:0005615; GO:0005737; GO:0005764; GO:0006508; GO:0007586; GO:0008233; GO:0008236; GO:0030163; GO:0034097; GO:0043065 3388 FUN_023403 976 611 286 864 516 ptg000017l:7171736-7192592 Q9CR35 1.47e-26 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Mus musculus (Mouse) digestion [GO:0007586]; positive regulation of apoptotic process [GO:0043065]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to cytokine [GO:0034097] GO:0004252; GO:0005615; GO:0005737; GO:0005764; GO:0006508; GO:0007586; GO:0008233; GO:0008236; GO:0030163; GO:0034097; GO:0043065 3389 FUN_023402 6751 5982 4448 8521 9851 ptg000017l:7157155-7169333 P11141 5.18e-33 Heat shock protein hsp-6 (Heat shock 70 kDa protein F, mitochondrial) Caenorhabditis elegans cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; mitochondrial unfolded protein response [GO:0034514]; protein refolding [GO:0042026] GO:0005524; GO:0005737; GO:0005739; GO:0016887; GO:0031072; GO:0034514; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 3390 FUN_023402 6751 5982 4448 8521 9851 ptg000017l:7157155-7169333 P11141 5.18e-33 Heat shock protein hsp-6 (Heat shock 70 kDa protein F, mitochondrial) Caenorhabditis elegans cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; mitochondrial unfolded protein response [GO:0034514]; protein refolding [GO:0042026] GO:0005524; GO:0005737; GO:0005739; GO:0016887; GO:0031072; GO:0034514; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 3391 FUN_023402 6751 5982 4448 8521 9851 ptg000017l:7157155-7169333 P11141 1.94e-25 Heat shock protein hsp-6 (Heat shock 70 kDa protein F, mitochondrial) Caenorhabditis elegans cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; mitochondrial unfolded protein response [GO:0034514]; protein refolding [GO:0042026] GO:0005524; GO:0005737; GO:0005739; GO:0016887; GO:0031072; GO:0034514; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 3392 FUN_023402 6751 5982 4448 8521 9851 ptg000017l:7157155-7169333 P11141 4.15e-25 Heat shock protein hsp-6 (Heat shock 70 kDa protein F, mitochondrial) Caenorhabditis elegans cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; mitochondrial unfolded protein response [GO:0034514]; protein refolding [GO:0042026] GO:0005524; GO:0005737; GO:0005739; GO:0016887; GO:0031072; GO:0034514; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 3393 FUN_023402 6751 5982 4448 8521 9851 ptg000017l:7157155-7169333 P11141 3.42e-22 Heat shock protein hsp-6 (Heat shock 70 kDa protein F, mitochondrial) Caenorhabditis elegans cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; mitochondrial unfolded protein response [GO:0034514]; protein refolding [GO:0042026] GO:0005524; GO:0005737; GO:0005739; GO:0016887; GO:0031072; GO:0034514; GO:0034620; GO:0042026; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 3394 FUN_023401 40 33 25 59 55 NA NA NA NA NA NA NA 3395 FUN_023400 2176 1312 1002 2401 1333 ptg000017l:7111934-7142987 Q03393 6.52e-49 6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12) Homo sapiens (Human) amino acid metabolic process [GO:0006520]; central nervous system development [GO:0007417]; tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0003874; GO:0005737; GO:0005739; GO:0005829; GO:0006520; GO:0006729; GO:0007417; GO:0042802; GO:0046872 3396 FUN_023407 498 115 92 427 783 ptg000017l:7210837-7213420 Q3THE2 1.79e-48 Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) Mus musculus (Mouse) regulation of cell shape [GO:0008360] GO:0001725; GO:0005509; GO:0005737; GO:0005903; GO:0005938; GO:0008360; GO:0016460; GO:0030016; GO:0030018; GO:0032036; GO:0032991; GO:0045177 3397 FUN_023406 2347 1641 1298 3194 4403 ptg000017l:7206209-7210017 Q5E9E2 1.34e-43 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Bos taurus (Bovine) actomyosin structure organization [GO:0031032] GO:0005509; GO:0005737; GO:0005938; GO:0016460; GO:0031032; GO:0032036; GO:0042641; GO:0097513 3398 FUN_023405 1583 1525 985 1162 1073 NA NA NA NA NA NA NA 3399 FUN_023404 112 80 26 83 45 ptg000017l:7193926-7194961 P14272 7.1e-37 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Rattus norvegicus (Rat) blood coagulation, intrinsic pathway [GO:0007597]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; liver regeneration [GO:0097421]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919]; proteolysis [GO:0006508]; zymogen activation [GO:0031638] GO:0004252; GO:0005615; GO:0006508; GO:0006954; GO:0007597; GO:0031638; GO:0031639; GO:0042730; GO:0051919; GO:0097421 3400 FUN_023408 451 397 183 419 198 NA NA NA NA NA NA NA 3401 FUN_039970 36 50 42 22 90 ptg000031l:2355775-2356759 P54833 1.8e-21 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Canis lupus familiaris (Dog) (Canis familiaris) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898] GO:0002025; GO:0002032; GO:0004930; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0045986; GO:0051380; GO:0071880; GO:1901098; GO:1904504 3402 FUN_039971 430 394 318 396 238 NA NA NA NA NA NA NA 3403 FUN_039972 3827 3877 2162 2831 1578 NA NA NA NA NA NA NA 3404 FUN_039973 1339 752 899 1215 1915 NA NA NA NA NA NA NA 3405 FUN_039974 765 489 538 697 765 NA NA NA NA NA NA NA 3406 FUN_039975 167 105 147 402 142 ptg000031l:2424066-2428355 Q9ULJ7 6.79e-33 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3407 FUN_039976 4026 969 940 4015 1166 ptg000031l:2440970-2537087 Q9ULJ7 2.34e-63 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3408 FUN_039976 4026 969 940 4015 1166 ptg000031l:2440970-2537087 Q9ULJ7 7.87e-54 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3409 FUN_039976 4026 969 940 4015 1166 ptg000031l:2440970-2537087 Q9ULJ7 2.57e-23 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3410 FUN_039976 4026 969 940 4015 1166 ptg000031l:2440970-2537087 Q9ULJ7 3.29e-23 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3411 FUN_039976 4026 969 940 4015 1166 ptg000031l:2440970-2537087 Q9ULJ7 3.7e-23 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3412 FUN_039977 8 13 347 450 316 ptg000031l:2540914-2548291 Q9ULJ7 6.09e-55 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3413 FUN_039977 8 13 347 450 316 ptg000031l:2540914-2548291 Q9ULJ7 6.26e-26 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3414 FUN_039977 8 13 347 450 316 ptg000031l:2540914-2548291 Q9ULJ7 2.87e-23 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 3415 FUN_039978 1029 705 623 1026 965 NA NA NA NA NA NA NA 3416 FUN_039979 429 337 360 358 382 NA NA NA NA NA NA NA 3417 FUN_014828 0 0 0 0 11 NA NA NA NA NA NA NA 3418 FUN_015368 0 1 0 32 0 NA NA NA NA NA NA NA 3419 FUN_015367 52 120 50 76 79 NA NA NA NA NA NA NA 3420 FUN_015366 4824 4874 3174 3849 3341 NA NA NA NA NA NA NA 3421 FUN_015365 617 299 248 683 522 NA NA NA NA NA NA NA 3422 FUN_015364 3 0 0 6 0 NA NA NA NA NA NA NA 3423 FUN_015363 5 14 3 5 6 NA NA NA NA NA NA NA 3424 FUN_015362 26 8 19 21 104 NA NA NA NA NA NA NA 3425 FUN_015361 286 983 1030 428 275 NA NA NA NA NA NA NA 3426 FUN_015360 1489 1700 728 1377 835 ptg000009l:9208943-9212959 Q5VU57 5.43e-104 Cytosolic carboxypeptidase 6 (EC 3.4.17.24) (ATP/GTP-binding protein-like 4) (Protein deglutamylase CCP6) Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; C-terminal protein deglutamylation [GO:0035609]; central nervous system neuron development [GO:0021954]; defense response to virus [GO:0051607]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508]; regulation of blastocyst development [GO:0120222]; retrograde axonal transport of mitochondrion [GO:0098958] GO:0004181; GO:0005794; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0008285; GO:0015631; GO:0021954; GO:0035608; GO:0035609; GO:0035610; GO:0036064; GO:0051607; GO:0098957; GO:0098958; GO:0120222; GO:1904115; GO:2000060 3427 FUN_015360 1489 1700 728 1377 835 ptg000009l:9208943-9212959 Q5VU57 4.92e-103 Cytosolic carboxypeptidase 6 (EC 3.4.17.24) (ATP/GTP-binding protein-like 4) (Protein deglutamylase CCP6) Homo sapiens (Human) anterograde axonal transport of mitochondrion [GO:0098957]; C-terminal protein deglutamylation [GO:0035609]; central nervous system neuron development [GO:0021954]; defense response to virus [GO:0051607]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508]; regulation of blastocyst development [GO:0120222]; retrograde axonal transport of mitochondrion [GO:0098958] GO:0004181; GO:0005794; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0008285; GO:0015631; GO:0021954; GO:0035608; GO:0035609; GO:0035610; GO:0036064; GO:0051607; GO:0098957; GO:0098958; GO:0120222; GO:1904115; GO:2000060 3428 FUN_018500 5313 6495 2304 4410 2728 NA NA NA NA NA NA NA 3429 FUN_018502 142 375 189 736 309 NA NA NA NA NA NA NA 3430 FUN_018503 279 234 155 359 303 NA NA NA NA NA NA NA 3431 FUN_018505 53 0 0 0 235 NA NA NA NA NA NA NA 3432 FUN_018508 3 21 6 5 26 NA NA NA NA NA NA NA 3433 FUN_018509 569 139 76 576 1604 NA NA NA NA NA NA NA 3434 FUN_000500 3089 2182 1428 2187 959 NA NA NA NA NA NA NA 3435 FUN_000503 7 0 287 0 0 NA NA NA NA NA NA NA 3436 FUN_000502 915 681 398 856 557 ntLink_6:3723440-3730892 Q2HJF7 1.28e-92 Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) Bos taurus (Bovine) positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0010613; GO:0033017; GO:0042383; GO:0043005; GO:0060341; GO:0106310 3437 FUN_000502 915 681 398 856 557 ntLink_6:3723440-3730892 Q2HJF7 2.5e-57 Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17) Bos taurus (Bovine) positive regulation of cardiac muscle hypertrophy [GO:0010613]; protein phosphorylation [GO:0006468]; regulation of cellular localization [GO:0060341] GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0010613; GO:0033017; GO:0042383; GO:0043005; GO:0060341; GO:0106310 3438 FUN_025122 0 0 0 0 25 NA NA NA NA NA NA NA 3439 FUN_025120 40 4 109 11 692 ptg000018l:14110211-14112478 Q9U7D0 2.01e-47 Histone H4 Mastigamoeba balamuthi (Phreatamoeba balamuthi) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3440 FUN_014824 61 0 46 19 365 NA NA NA NA NA NA NA 3441 FUN_017884 34 13 5 18 0 NA NA NA NA NA NA NA 3442 FUN_017885 341 224 116 230 150 ptg000012l:1602909-1607656 Q5EAB6 2.56e-30 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 3443 FUN_017885 341 224 116 230 150 ptg000012l:1602909-1607656 Q5EAB6 1.1e-25 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 3444 FUN_017885 341 224 116 230 150 ptg000012l:1602909-1607656 Q5EAB6 6.94e-22 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 3445 FUN_024839 142 54 0 22 139 NA NA NA NA NA NA NA 3446 FUN_017887 25 8 9 0 0 NA NA NA NA NA NA NA 3447 FUN_017880 424 227 277 532 491 ptg000012l:1533767-1536104 Q9VH19 1.56e-96 Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; electron transport chain [GO:0022900]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; lipid storage [GO:0019915]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteolysis [GO:0006508]; regulation of choline O-acetyltransferase activity [GO:1902769] GO:0004222; GO:0005737; GO:0006338; GO:0006508; GO:0007052; GO:0007076; GO:0007100; GO:0007155; GO:0007420; GO:0007444; GO:0008233; GO:0008354; GO:0008406; GO:0016020; GO:0019915; GO:0022900; GO:0045842; GO:0046872; GO:0051298; GO:0051301; GO:1902769 3448 FUN_017880 424 227 277 532 491 ptg000012l:1533767-1536104 Q9VH19 2.17e-45 Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; electron transport chain [GO:0022900]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; lipid storage [GO:0019915]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteolysis [GO:0006508]; regulation of choline O-acetyltransferase activity [GO:1902769] GO:0004222; GO:0005737; GO:0006338; GO:0006508; GO:0007052; GO:0007076; GO:0007100; GO:0007155; GO:0007420; GO:0007444; GO:0008233; GO:0008354; GO:0008406; GO:0016020; GO:0019915; GO:0022900; GO:0045842; GO:0046872; GO:0051298; GO:0051301; GO:1902769 3449 FUN_017881 3547 3744 1898 3260 2695 NA NA NA NA NA NA NA 3450 FUN_017882 4397 2732 2383 5717 3774 NA NA NA NA NA NA NA 3451 FUN_017883 2871 1921 1353 2400 1933 ptg000012l:1569713-1590411 Q7TT49 2.38e-37 Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0005886; GO:0005911; GO:0006468; GO:0016477; GO:0018107; GO:0030027; GO:0030036; GO:0031032; GO:0031252; GO:0031267; GO:0031532; GO:0042641; GO:0044877; GO:0106310 3452 FUN_017883 2871 1921 1353 2400 1933 ptg000012l:1569713-1590411 Q7TT49 2.38e-37 Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0005886; GO:0005911; GO:0006468; GO:0016477; GO:0018107; GO:0030027; GO:0030036; GO:0031032; GO:0031252; GO:0031267; GO:0031532; GO:0042641; GO:0044877; GO:0106310 3453 FUN_017883 2871 1921 1353 2400 1933 ptg000012l:1569713-1590411 Q7TT49 2.38e-37 Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actomyosin structure organization [GO:0031032]; cell migration [GO:0016477]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005856; GO:0005886; GO:0005911; GO:0006468; GO:0016477; GO:0018107; GO:0030027; GO:0030036; GO:0031032; GO:0031252; GO:0031267; GO:0031532; GO:0042641; GO:0044877; GO:0106310 3454 FUN_024833 44 0 0 39 44 NA NA NA NA NA NA NA 3455 FUN_017888 77 91 78 59 188 ptg000012l:1611757-1615050 Q5EAB6 1.24e-34 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 3456 FUN_017888 77 91 78 59 188 ptg000012l:1611757-1615050 Q5EAB6 1.24e-34 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 3457 FUN_017888 77 91 78 59 188 ptg000012l:1611757-1615050 Q5EAB6 8.78e-26 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 3458 FUN_017889 690 5885 817 1852 455 ptg000012l:1618336-1618879 Q90X67 2.59e-28 Suppressor of cytokine signaling 3 (SOCS-3) Gallus gallus (Chicken) intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein ubiquitination [GO:0016567] GO:0005942; GO:0009968; GO:0016567; GO:0035556; GO:0046854; GO:0046935 3459 FUN_024834 15 0 6 0 44 NA NA NA NA NA NA NA 3460 FUN_014566 1705 1393 1172 1094 562 NA NA NA NA NA NA NA 3461 FUN_014565 4865 4351 3497 6571 5697 ptg000009l:1195136-1196331 Q9ZH77 2.38e-23 Malate synthase (EC 2.3.3.9) Streptomyces clavuligerus glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004474; GO:0005737; GO:0006097; GO:0006099 3462 FUN_014562 2367 2015 2253 3020 868 ptg000009l:1182300-1183612 A2BIR6 3.53e-26 Carbohydrate deacetylase (EC 3.5.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate metabolic process [GO:0005975] GO:0000287; GO:0005975; GO:0019213 3463 FUN_001540 3 2 12 95 91 NA NA NA NA NA NA NA 3464 FUN_001541 2 21 3 95 89 NA NA NA NA NA NA NA 3465 FUN_014560 4711 2330 2429 3448 4051 ptg000009l:1167509-1174830 Q3TY86 7.43e-26 Apoptosis-inducing factor 3 (EC 1.-.-.-) (Apoptosis-inducing factor-like protein) Mus musculus (Mouse) execution phase of apoptosis [GO:0097194] GO:0005737; GO:0005739; GO:0005743; GO:0005783; GO:0005829; GO:0016651; GO:0046872; GO:0050660; GO:0051537; GO:0097194 3466 FUN_014561 1442 1265 944 1561 1256 NA NA NA NA NA NA NA 3467 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 1.49e-54 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3468 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 1.49e-54 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3469 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 6.67e-39 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3470 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 9.55e-31 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3471 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 2.82e-24 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3472 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 5.07e-24 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3473 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 1.19e-23 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3474 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 1.75e-23 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3475 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 3.83e-23 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3476 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 1.02e-21 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3477 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 1.75e-21 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3478 FUN_001547 4136 2059 1786 3870 2944 ntLink_6:13534450-13623215 Q63164 9.55e-21 Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) Rattus norvegicus (Rat) cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018]; sperm axoneme assembly [GO:0007288] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005874; GO:0005930; GO:0007018; GO:0007288; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060294 3479 FUN_001544 3 28 0 69 42 NA NA NA NA NA NA NA 3480 FUN_019673 0 0 3 0 37 NA NA NA NA NA NA NA 3481 FUN_014287 0 0 0 0 9 NA NA NA NA NA NA NA 3482 FUN_019674 0 0 0 3 27 NA NA NA NA NA NA NA 3483 FUN_019678 24 0 12 16 52 NA NA NA NA NA NA NA 3484 FUN_044215 8 8 28 4 178 NA NA NA NA NA NA NA 3485 FUN_030165 8 0 6 29 0 NA NA NA NA NA NA NA 3486 FUN_044216 5 8 10 16 31 NA NA NA NA NA NA NA 3487 FUN_044211 7 3 21 7 151 NA NA NA NA NA NA NA 3488 FUN_044210 75 157 178 159 402 NA NA NA NA NA NA NA 3489 FUN_030162 221 0 0 0 159 NA NA NA NA NA NA NA 3490 FUN_044212 5 10 14 20 32 NA NA NA NA NA NA NA 3491 FUN_038313 1469 1244 825 1589 1621 ptg000027l:5590196-5613999 Q9W1H4 2.33e-29 DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (DmDNA Lig I) Drosophila melanogaster (Fruit fly) cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; lagging strand elongation [GO:0006273]; Okazaki fragment processing involved in mitotic DNA replication [GO:1903461] GO:0003677; GO:0003910; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0006266; GO:0006273; GO:0006281; GO:0006310; GO:0051301; GO:0071897; GO:1903461 3492 FUN_038312 16744 19669 9536 12602 8264 ptg000027l:5584467-5588947 P40792 4.51e-39 Ras-related protein Rac1 Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; activation of protein kinase activity [GO:0032147]; axon extension [GO:0048675]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; axonal fasciculation [GO:0007413]; border follicle cell migration [GO:0007298]; cell competition in a multicellular organism [GO:0035212]; cell morphogenesis [GO:0000902]; cortical actin cytoskeleton organization [GO:0030866]; cortical cytoskeleton organization [GO:0030865]; dendrite development [GO:0016358]; determination of digestive tract left/right asymmetry [GO:0071907]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal closure, amnioserosa morphology change [GO:0046664]; dorsal closure, elongation of leading edge cells [GO:0007394]; dorsal closure, spreading of leading edge cells [GO:0007395]; embryonic anterior midgut (ectodermal) morphogenesis [GO:0048615]; encapsulation of foreign target [GO:0035010]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; germ-band shortening [GO:0007390]; glial cell migration [GO:0008347]; head involution [GO:0008258]; hemocyte development [GO:0007516]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair site selection [GO:0035320]; immune response-regulating cell surface receptor signaling pathway involved in phagocytosis [GO:0002433]; JNK cascade [GO:0007254]; lamellipodium assembly [GO:0030032]; melanotic encapsulation of foreign target [GO:0035011]; memory [GO:0007613]; mesodermal cell migration [GO:0008078]; motor neuron axon guidance [GO:0008045]; muscle attachment [GO:0016203]; muscle cell development [GO:0055001]; myoblast fusion [GO:0007520]; myoblast proliferation [GO:0051450]; negative regulation of lamellipodium assembly [GO:0010593]; negative regulation of myotube cell migration [GO:0110125]; nephrocyte filtration [GO:0097206]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; open tracheal system development [GO:0007424]; peripheral nervous system development [GO:0007422]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; positive regulation of border follicle cell migration [GO:1903688]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of wound healing [GO:0090303]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of adherens junction organization [GO:1903391]; regulation of axonogenesis [GO:0050770]; regulation of cell shape [GO:0008360]; regulation of dendrite morphogenesis [GO:0048814]; regulation of locomotor rhythm [GO:1904059]; regulation of synapse assembly [GO:0051963]; regulation of synapse organization [GO:0050807]; response to wounding [GO:0009611]; rhabdomere development [GO:0042052]; salivary gland morphogenesis [GO:0007435]; sensory perception of touch [GO:0050975]; small GTPase mediated signal transduction [GO:0007264]; tracheal outgrowth, open tracheal system [GO:0007426]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; ventral cord development [GO:0007419] GO:0000902; GO:0001726; GO:0001954; GO:0002433; GO:0003924; GO:0005525; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007254; GO:0007264; GO:0007298; GO:0007390; GO:0007391; GO:0007394; GO:0007395; GO:0007411; GO:0007413; GO:0007419; GO:0007422; GO:0007424; GO:0007426; GO:0007435; GO:0007516; GO:0007520; GO:0007613; GO:0008045; GO:0008078; GO:0008258; GO:0008347; GO:0008360; GO:0009611; GO:0010593; GO:0016028; GO:0016199; GO:0016203; GO:0016358; GO:0019901; GO:0030032; GO:0030036; GO:0030865; GO:0030866; GO:0031175; GO:0031410; GO:0031532; GO:0032147; GO:0032794; GO:0032956; GO:0035010; GO:0035011; GO:0035099; GO:0035212; GO:0035320; GO:0042052; GO:0042995; GO:0043652; GO:0045773; GO:0046330; GO:0046664; GO:0046843; GO:0048010; GO:0048615; GO:0048675; GO:0048812; GO:0048814; GO:0050770; GO:0050807; GO:0050975; GO:0051017; GO:0051450; GO:0051491; GO:0051963; GO:0055001; GO:0071902; GO:0071907; GO:0090303; GO:0097206; GO:0110125; GO:1902669; GO:1903391; GO:1903688; GO:1904059 3493 FUN_038311 88615 83778 48457 57449 23768 ptg000027l:5576447-5577699 P50616 2.54e-38 Protein Tob1 (Transducer of erbB-2 1) Homo sapiens (Human) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of translation [GO:0017148]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of gene expression [GO:0010468]; regulation of SMAD protein signal transduction [GO:0060390] GO:0003714; GO:0005634; GO:0005737; GO:0008285; GO:0010468; GO:0017148; GO:0030014; GO:0030514; GO:0030971; GO:0045668; GO:0046332; GO:0060212; GO:0060213; GO:0060390; GO:1900153 3494 FUN_038310 4244 1776 639 2561 2321 NA NA NA NA NA NA NA 3495 FUN_038316 33 3 47 0 14 NA NA NA NA NA NA NA 3496 FUN_038315 1093 790 1012 1561 1571 NA NA NA NA NA NA NA 3497 FUN_038314 1266 1107 626 1136 713 NA NA NA NA NA NA NA 3498 FUN_031694 44 30 39 0 126 NA NA NA NA NA NA NA 3499 FUN_001975 0 0 6 2 7 NA NA NA NA NA NA NA 3500 FUN_031696 1379 862 501 788 868 NA NA NA NA NA NA NA 3501 FUN_031691 54 126 8 68 26 NA NA NA NA NA NA NA 3502 FUN_031690 8 40 35 64 292 NA NA NA NA NA NA NA 3503 FUN_031692 408 180 111 363 333 ptg000023l:24433518-24440378 A1L1W9 6.89e-22 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 3504 FUN_004520 1325 684 624 636 986 NA NA NA NA NA NA NA 3505 FUN_031699 5148 7451 5760 6614 5654 NA NA NA NA NA NA NA 3506 FUN_004528 40 30 14 60 147 NA NA NA NA NA NA NA 3507 FUN_024572 59 0 0 45 126 NA NA NA NA NA NA NA 3508 FUN_039196 0 8 0 9 6 NA NA NA NA NA NA NA 3509 FUN_039197 21 9 7 24 28 NA NA NA NA NA NA NA 3510 FUN_027713 0 0 3 0 6 NA NA NA NA NA NA NA 3511 FUN_027712 4 1 1 0 9 NA NA NA NA NA NA NA 3512 FUN_027717 0 0 8 0 0 NA NA NA NA NA NA NA 3513 FUN_027715 0 0 0 0 35 NA NA NA NA NA NA NA 3514 FUN_027714 19 6 0 0 134 NA NA NA NA NA NA NA 3515 FUN_008165 20 14 0 0 11 NA NA NA NA NA NA NA 3516 FUN_024575 125 0 3 890 101 NA NA NA NA NA NA NA 3517 FUN_036640 22 11 2 9 11 NA NA NA NA NA NA NA 3518 FUN_036647 2 0 13 0 20 NA NA NA NA NA NA NA 3519 FUN_036645 0 0 0 0 16 ptg000026l:365191-366691 Q6LAF1 1.64e-43 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3520 FUN_024579 0 75 10 123 77 ptg000018l:8606291-8608481 Q7RTR2 3.48e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3521 FUN_024579 0 75 10 123 77 ptg000018l:8606291-8608481 Q7RTR2 7.84e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3522 FUN_024579 0 75 10 123 77 ptg000018l:8606291-8608481 Q7RTR2 1.79e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3523 FUN_024579 0 75 10 123 77 ptg000018l:8606291-8608481 Q7RTR2 4.89e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3524 FUN_037590 774 1378 286 782 500 ptg000026l:12075040-12091985 P0CT39 1.14e-88 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 3525 FUN_037591 552 601 443 681 483 NA NA NA NA NA NA NA 3526 FUN_037592 35 51 94 118 5 NA NA NA NA NA NA NA 3527 FUN_037593 897 635 351 702 433 ptg000026l:12105183-12162897 S4R1M9 2.88e-26 Oxysterol-binding protein-related protein 10 (ORP-10) (OSBP-related protein 10) Mus musculus (Mouse) lipid metabolic process [GO:0006629] GO:0001786; GO:0005829; GO:0005856; GO:0006629; GO:0015248; GO:0015485; GO:0016020; GO:0032934; GO:0043231 3528 FUN_037594 16 9 20 5 5 NA NA NA NA NA NA NA 3529 FUN_037595 149 145 52 240 195 NA NA NA NA NA NA NA 3530 FUN_037596 0 0 0 9 7 NA NA NA NA NA NA NA 3531 FUN_000645 0 8 21 21 0 NA NA NA NA NA NA NA 3532 FUN_019769 0 0 0 0 11 NA NA NA NA NA NA NA 3533 FUN_014251 28 0 12 0 93 NA NA NA NA NA NA NA 3534 FUN_029991 0 0 21 0 32 NA NA NA NA NA NA NA 3535 FUN_031348 0 0 40 0 22 NA NA NA NA NA NA NA 3536 FUN_031347 0 0 0 0 22 NA NA NA NA NA NA NA 3537 FUN_031345 50 0 17 3 0 ptg000023l:19876615-19891749 Q7RTR2 1.29e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3538 FUN_031345 50 0 17 3 0 ptg000023l:19876615-19891749 Q7RTR2 8.22e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3539 FUN_031342 92 0 1 4 34 NA NA NA NA NA NA NA 3540 FUN_031340 19 0 11 0 104 NA NA NA NA NA NA NA 3541 FUN_005968 2377 1486 814 2622 2156 NA NA NA NA NA NA NA 3542 FUN_006749 2689 4292 1718 2337 2227 ptg000001l:16182396-16185816 P70011 6.6e-22 Nucleoside diphosphate kinase A2 (NDK A2) (NDP kinase A2) (EC 2.7.4.6) (NM23/nucleoside diphosphate kinase A2) Xenopus laevis (African clawed frog) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005737; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 3543 FUN_006749 2689 4292 1718 2337 2227 ptg000001l:16182396-16185816 P70011 6.6e-22 Nucleoside diphosphate kinase A2 (NDK A2) (NDP kinase A2) (EC 2.7.4.6) (NM23/nucleoside diphosphate kinase A2) Xenopus laevis (African clawed frog) CTP biosynthetic process [GO:0006241]; GTP biosynthetic process [GO:0006183]; nucleoside diphosphate phosphorylation [GO:0006165]; UTP biosynthetic process [GO:0006228] GO:0004550; GO:0005524; GO:0005737; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0046872 3544 FUN_006748 7129 7298 3496 6848 5911 NA NA NA NA NA NA NA 3545 FUN_006745 0 0 0 8 0 NA NA NA NA NA NA NA 3546 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 0 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3547 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.19e-112 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3548 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2.56e-104 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3549 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.38e-87 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3550 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.97e-80 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3551 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 6.35e-79 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3552 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 7.12e-75 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3553 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 9.35e-70 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3554 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 5.98e-58 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3555 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 4.38e-57 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3556 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.81e-52 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3557 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.56e-51 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3558 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.7e-50 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3559 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 4.59e-49 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3560 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.28e-48 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3561 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 9.1e-47 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3562 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2.93e-44 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3563 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.4e-44 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3564 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.73e-41 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3565 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 5.09e-40 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3566 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.61e-39 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3567 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 8.31e-38 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3568 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 6.35e-37 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3569 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2.57e-36 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3570 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.65e-36 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3571 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.79e-35 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3572 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.13e-34 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3573 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.83e-33 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3574 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 5.2e-33 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3575 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 4.98e-32 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3576 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 5.59e-31 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3577 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.76e-29 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3578 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 7.65e-29 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3579 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2.73e-28 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3580 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.09e-27 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3581 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2e-27 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3582 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.27e-27 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3583 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 5.06e-27 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3584 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.05e-25 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3585 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 7.28e-25 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3586 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.45e-24 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3587 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 9.11e-24 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3588 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 5.74e-23 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3589 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2.44e-22 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3590 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.08e-22 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3591 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 3.77e-22 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3592 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 1.54e-21 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3593 FUN_006744 5986 4128 4999 8442 7649 ptg000001l:16124413-16150024 Q14517 2.06e-21 Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form] Homo sapiens (Human) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cell-cell signaling [GO:0007267]; epithelial cell morphogenesis [GO:0003382]; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis [GO:0003412]; establishment or maintenance of cell polarity [GO:0007163]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; lens development in camera-type eye [GO:0002088] GO:0002088; GO:0003382; GO:0003412; GO:0005509; GO:0005634; GO:0005886; GO:0005911; GO:0005925; GO:0007015; GO:0007155; GO:0007156; GO:0007163; GO:0007267; GO:0009653; GO:0016324; GO:0016477; GO:0030027; GO:0030175; GO:0048471; GO:0070062; GO:0098609 3594 FUN_006747 6 9 4 27 20 NA NA NA NA NA NA NA 3595 FUN_006741 93 1 0 3 3 NA NA NA NA NA NA NA 3596 FUN_006740 872 454 313 1123 226 NA NA NA NA NA NA NA 3597 FUN_006743 1384 594 356 1126 1623 ptg000001l:16114480-16121729 Q9SHZ0 3.72e-22 Protease Do-like 4, mitochondrial (EC 3.4.21.-) Arabidopsis thaliana (Mouse-ear cress) proteolysis [GO:0006508] GO:0004252; GO:0006508; GO:0031966 3598 FUN_006743 1384 594 356 1126 1623 ptg000001l:16114480-16121729 Q9SHZ0 3.72e-22 Protease Do-like 4, mitochondrial (EC 3.4.21.-) Arabidopsis thaliana (Mouse-ear cress) proteolysis [GO:0006508] GO:0004252; GO:0006508; GO:0031966 3599 FUN_006742 3550 2889 686 1700 2454 NA NA NA NA NA NA NA 3600 FUN_001090 51 110 38 26 215 NA NA NA NA NA NA NA 3601 FUN_025963 1083 809 375 1229 1256 NA NA NA NA NA NA NA 3602 FUN_020954 0 0 0 0 256 NA NA NA NA NA NA NA 3603 FUN_039261 16 0 9 0 79 NA NA NA NA NA NA NA 3604 FUN_033560 8 29 76 3 7 NA NA NA NA NA NA NA 3605 FUN_039264 485 241 284 445 467 NA NA NA NA NA NA NA 3606 FUN_020951 31 0 175 89 113 NA NA NA NA NA NA NA 3607 FUN_001211 953 1081 526 884 707 NA NA NA NA NA NA NA 3608 FUN_001216 2105 1042 1320 1822 1423 NA NA NA NA NA NA NA 3609 FUN_001217 707 642 524 569 628 ntLink_6:9917615-9919074 Q8BGF9 2.79e-51 Solute carrier family 25 member 44 Mus musculus (Mouse) branched-chain amino acid catabolic process [GO:0009083]; branched-chain amino acid transport [GO:0015803]; regulation of cold-induced thermogenesis [GO:0120161] GO:0005739; GO:0005743; GO:0009083; GO:0015658; GO:0015803; GO:0120161 3610 FUN_001214 3932 2862 1920 3234 2453 ntLink_6:9865534-9872126 P48463 3.06e-56 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) Gallus gallus (Chicken) mitotic cell cycle [GO:0000278]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227] GO:0000278; GO:0000775; GO:0000922; GO:0004722; GO:0005634; GO:0005829; GO:0017018; GO:0046872; GO:0046982; GO:1900227 3611 FUN_001214 3932 2862 1920 3234 2453 ntLink_6:9865534-9872126 P48463 3.06e-56 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) Gallus gallus (Chicken) mitotic cell cycle [GO:0000278]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227] GO:0000278; GO:0000775; GO:0000922; GO:0004722; GO:0005634; GO:0005829; GO:0017018; GO:0046872; GO:0046982; GO:1900227 3612 FUN_001214 3932 2862 1920 3234 2453 ntLink_6:9865534-9872126 P48463 2.42e-27 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) Gallus gallus (Chicken) mitotic cell cycle [GO:0000278]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227] GO:0000278; GO:0000775; GO:0000922; GO:0004722; GO:0005634; GO:0005829; GO:0017018; GO:0046872; GO:0046982; GO:1900227 3613 FUN_001215 1641 890 883 1631 1492 NA NA NA NA NA NA NA 3614 FUN_001218 852 492 243 475 299 ntLink_6:9921543-9922566 Q3USF0 5.56e-37 Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase (EC 2.4.1.147) (Core 3 synthase) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6) (BGnT-6) (Beta-1,3-Gn-T6) (Beta-1,3-N-acetylglucosaminyltransferase 6) (Beta3Gn-T6) Mus musculus (Mouse) poly-N-acetyllactosamine biosynthetic process [GO:0030311]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008194; GO:0008378; GO:0016757; GO:0030311; GO:0106327; GO:0106328 3615 FUN_004456 59 34 25 61 21 NA NA NA NA NA NA NA 3616 FUN_004455 15224 10923 12127 11697 11840 ntLink_8:23393748-23418709 Q8K1T0 1.46e-24 Transmembrane protease serine 3 (EC 3.4.21.-) Mus musculus (Mouse) cellular sodium ion homeostasis [GO:0006883]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605] GO:0004252; GO:0005044; GO:0005783; GO:0005789; GO:0006508; GO:0006883; GO:0007605; GO:0017080; GO:0043025 3617 FUN_004454 1442 1118 1046 1147 1077 NA NA NA NA NA NA NA 3618 FUN_004453 1754 989 788 868 653 NA NA NA NA NA NA NA 3619 FUN_004452 581 190 239 408 421 NA NA NA NA NA NA NA 3620 FUN_004451 58 167 63 86 79 NA NA NA NA NA NA NA 3621 FUN_004450 445 520 189 669 357 NA NA NA NA NA NA NA 3622 FUN_004459 36 84 33 37 22 NA NA NA NA NA NA NA 3623 FUN_004458 1519 1962 1143 1798 1283 ntLink_8:23447100-23447658 A2VDD2 6.17e-28 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 3624 FUN_007904 43052 51451 16424 22015 16362 NA NA NA NA NA NA NA 3625 FUN_007905 22081 48461 9379 22858 7610 NA NA NA NA NA NA NA 3626 FUN_007906 0 0 0 0 6 NA NA NA NA NA NA NA 3627 FUN_007907 14372 21508 6674 13853 2196 NA NA NA NA NA NA NA 3628 FUN_007900 27236 41602 13909 19211 9775 NA NA NA NA NA NA NA 3629 FUN_007901 58 8 62 0 70 ptg000002l:6063104-6067366 Q9Z2E3 2.89e-57 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 3630 FUN_007903 1875 508 1073 331 2321 NA NA NA NA NA NA NA 3631 FUN_007908 294 215 149 257 209 NA NA NA NA NA NA NA 3632 FUN_007909 312 556 61 175 58 ptg000002l:6099408-6101444 A8J4S9 1.77e-176 Trehalase (EC 3.2.1.28) (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase) Apis mellifera (Honeybee) trehalose metabolic process [GO:0005991] GO:0004555; GO:0005991; GO:0016020 3633 FUN_007189 8 7 12 1 97 NA NA NA NA NA NA NA 3634 FUN_025823 3944 2743 1919 3747 4306 ptg000020l:1001303-1026455 P53396 6.87e-52 ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme) Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; cholesterol biosynthetic process [GO:0006695]; citrate metabolic process [GO:0006101]; coenzyme A metabolic process [GO:0015936]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] GO:0003878; GO:0005524; GO:0005576; GO:0005654; GO:0005829; GO:0006085; GO:0006099; GO:0006101; GO:0006107; GO:0006633; GO:0006695; GO:0008610; GO:0015936; GO:0016020; GO:0035578; GO:0046872; GO:0070062; GO:1904813 3635 FUN_025823 3944 2743 1919 3747 4306 ptg000020l:1001303-1026455 P53396 6.87e-52 ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme) Homo sapiens (Human) acetyl-CoA biosynthetic process [GO:0006085]; cholesterol biosynthetic process [GO:0006695]; citrate metabolic process [GO:0006101]; coenzyme A metabolic process [GO:0015936]; fatty acid biosynthetic process [GO:0006633]; lipid biosynthetic process [GO:0008610]; oxaloacetate metabolic process [GO:0006107]; tricarboxylic acid cycle [GO:0006099] GO:0003878; GO:0005524; GO:0005576; GO:0005654; GO:0005829; GO:0006085; GO:0006099; GO:0006101; GO:0006107; GO:0006633; GO:0006695; GO:0008610; GO:0015936; GO:0016020; GO:0035578; GO:0046872; GO:0070062; GO:1904813 3636 FUN_025822 3299 1978 1654 2714 2242 NA NA NA NA NA NA NA 3637 FUN_025821 1680 664 790 1227 711 ptg000020l:913060-926423 O54853 9.66e-42 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 3638 FUN_025821 1680 664 790 1227 711 ptg000020l:913060-926423 O54853 7.19e-38 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 3639 FUN_025821 1680 664 790 1227 711 ptg000020l:913060-926423 O54853 4.07e-37 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 3640 FUN_025821 1680 664 790 1227 711 ptg000020l:913060-926423 O54853 4.07e-37 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 3641 FUN_025821 1680 664 790 1227 711 ptg000020l:913060-926423 O54853 2.02e-23 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 3642 FUN_025820 302 673 200 1397 345 NA NA NA NA NA NA NA 3643 FUN_025827 212 33 206 30 64 ptg000020l:1083544-1089113 B8V7Q1 5.14e-142 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3644 FUN_025827 212 33 206 30 64 ptg000020l:1083544-1089113 B8V7Q1 5.91e-31 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3645 FUN_025827 212 33 206 30 64 ptg000020l:1083544-1089113 B8V7Q1 1.99e-28 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3646 FUN_025827 212 33 206 30 64 ptg000020l:1083544-1089113 B8V7Q1 1.99e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3647 FUN_025827 212 33 206 30 64 ptg000020l:1083544-1089113 B8V7Q1 2.95e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3648 FUN_025827 212 33 206 30 64 ptg000020l:1083544-1089113 B8V7Q1 3.18e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3649 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3650 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.22e-132 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3651 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.46e-46 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3652 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 9.56e-41 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3653 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.73e-37 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3654 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 2.65e-36 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3655 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 4.45e-36 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3656 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 4.45e-36 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3657 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 9.76e-35 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3658 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 3.22e-29 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3659 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.46e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3660 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.6e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3661 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.84e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3662 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.2e-24 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3663 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 4.99e-24 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3664 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 8.03e-23 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3665 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.89e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3666 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 8.5e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3667 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 1.49e-21 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3668 FUN_025826 171 173 124 198 222 ptg000020l:1062176-1080877 B8V7Q1 2.32e-21 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 3669 FUN_025825 1554 760 834 1034 850 NA NA NA NA NA NA NA 3670 FUN_025824 7640 4651 3526 10133 9605 ptg000020l:1032221-1039086 Q9GM70 3.27e-22 Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0006915; GO:0035556; GO:0043065; GO:0106310; GO:2000377 3671 FUN_025824 7640 4651 3526 10133 9605 ptg000020l:1032221-1039086 Q9GM70 3.27e-22 Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1) (rDRAK1) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; intracellular signal transduction [GO:0035556]; positive regulation of apoptotic process [GO:0043065]; protein phosphorylation [GO:0006468]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0006915; GO:0035556; GO:0043065; GO:0106310; GO:2000377 3672 FUN_025829 51 0 0 0 0 NA NA NA NA NA NA NA 3673 FUN_025828 284 55 101 25 121 ptg000020l:1089530-1095787 Q8K3Z0 9.16e-28 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 3674 FUN_035857 1402 1231 738 1047 368 ptg000025l:12587448-12597212 O97860 1.57e-21 Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase) Oryctolagus cuniculus (Rabbit) NA GO:0003993; GO:0005764; GO:0008198; GO:0008199 3675 FUN_035856 34 0 12 0 0 NA NA NA NA NA NA NA 3676 FUN_035855 47 11 0 4 12 NA NA NA NA NA NA NA 3677 FUN_035853 289 155 197 148 142 NA NA NA NA NA NA NA 3678 FUN_035852 801 628 498 973 1169 NA NA NA NA NA NA NA 3679 FUN_035851 57 2 73 19 45 NA NA NA NA NA NA NA 3680 FUN_035850 293 171 413 347 167 NA NA NA NA NA NA NA 3681 FUN_035859 1169 513 615 926 1332 NA NA NA NA NA NA NA 3682 FUN_035858 29 0 0 0 0 NA NA NA NA NA NA NA 3683 FUN_018269 19 0 0 49 0 NA NA NA NA NA NA NA 3684 FUN_018268 219 29 135 416 154 ptg000012l:6880975-6884953 Q9Y6N7 1.2e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 3685 FUN_018261 2223 330 335 1439 230 NA NA NA NA NA NA NA 3686 FUN_018260 874 284 175 1027 316 NA NA NA NA NA NA NA 3687 FUN_018263 7 37 0 99 19 NA NA NA NA NA NA NA 3688 FUN_018262 65 3 80 140 384 NA NA NA NA NA NA NA 3689 FUN_018265 338 196 157 140 902 NA NA NA NA NA NA NA 3690 FUN_018267 138 5 0 329 53 NA NA NA NA NA NA NA 3691 FUN_018266 501 34 67 403 62 NA NA NA NA NA NA NA 3692 FUN_040967 6 0 0 0 16 NA NA NA NA NA NA NA 3693 FUN_040966 1113 1754 515 1121 1392 NA NA NA NA NA NA NA 3694 FUN_040965 584 458 207 411 573 ptg000033l:620843-622515 A7SGU3 1.16e-95 Dynactin subunit 6 Nematostella vectensis (Starlet sea anemone) mitotic spindle organization [GO:0007052] GO:0005737; GO:0005869; GO:0007052; GO:0070840 3695 FUN_040964 944 1569 492 830 1560 ptg000033l:585577-616972 P10978 1.28e-21 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 3696 FUN_040964 944 1569 492 830 1560 ptg000033l:585577-616972 P10978 1.28e-21 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 3697 FUN_040962 371 417 141 317 508 ptg000033l:548125-574458 Q9JHP7 3.01e-28 Protein O-glucosyltransferase 2 (EC 2.4.1.-) (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58) (KDEL motif-containing protein 1) (Protein O-xylosyltransferase POGLUT2) (EC 2.4.2.-) Mus musculus (Mouse) protein O-linked glycosylation via serine [GO:0018242] GO:0005654; GO:0005788; GO:0005829; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0046527; GO:0140561; GO:0140562 3698 FUN_040962 371 417 141 317 508 ptg000033l:548125-574458 Q9JHP7 6.46e-22 Protein O-glucosyltransferase 2 (EC 2.4.1.-) (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58) (KDEL motif-containing protein 1) (Protein O-xylosyltransferase POGLUT2) (EC 2.4.2.-) Mus musculus (Mouse) protein O-linked glycosylation via serine [GO:0018242] GO:0005654; GO:0005788; GO:0005829; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0046527; GO:0140561; GO:0140562 3699 FUN_040962 371 417 141 317 508 ptg000033l:548125-574458 Q9JHP7 1.35e-21 Protein O-glucosyltransferase 2 (EC 2.4.1.-) (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58) (KDEL motif-containing protein 1) (Protein O-xylosyltransferase POGLUT2) (EC 2.4.2.-) Mus musculus (Mouse) protein O-linked glycosylation via serine [GO:0018242] GO:0005654; GO:0005788; GO:0005829; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0046527; GO:0140561; GO:0140562 3700 FUN_040962 371 417 141 317 508 ptg000033l:548125-574458 Q9JHP7 1.35e-21 Protein O-glucosyltransferase 2 (EC 2.4.1.-) (Endoplasmic reticulum resident protein 58) (ER protein 58) (ERp58) (KDEL motif-containing protein 1) (Protein O-xylosyltransferase POGLUT2) (EC 2.4.2.-) Mus musculus (Mouse) protein O-linked glycosylation via serine [GO:0018242] GO:0005654; GO:0005788; GO:0005829; GO:0012505; GO:0018242; GO:0035251; GO:0035252; GO:0046527; GO:0140561; GO:0140562 3701 FUN_040961 29 19 9 14 14 NA NA NA NA NA NA NA 3702 FUN_040960 1191 1807 869 3626 2115 NA NA NA NA NA NA NA 3703 FUN_034102 166 94 158 236 121 NA NA NA NA NA NA NA 3704 FUN_034103 0 63 74 59 65 NA NA NA NA NA NA NA 3705 FUN_034100 841 463 219 855 404 NA NA NA NA NA NA NA 3706 FUN_034101 117 111 24 95 93 NA NA NA NA NA NA NA 3707 FUN_034106 0 28 21 141 0 NA NA NA NA NA NA NA 3708 FUN_034107 565 516 106 684 171 NA NA NA NA NA NA NA 3709 FUN_034104 90 46 15 50 0 NA NA NA NA NA NA NA 3710 FUN_034105 9 23 0 53 0 NA NA NA NA NA NA NA 3711 FUN_034108 241 53 115 284 153 ptg000024l:4937861-4942325 P17972 6.36e-53 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 3712 FUN_034108 241 53 115 284 153 ptg000024l:4937861-4942325 P17972 2.19e-46 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 3713 FUN_034109 2110 1442 552 1632 1283 NA NA NA NA NA NA NA 3714 FUN_010568 243 121 11 41 57 NA NA NA NA NA NA NA 3715 FUN_028037 538 344 223 253 313 NA NA NA NA NA NA NA 3716 FUN_028036 162 130 127 226 54 NA NA NA NA NA NA NA 3717 FUN_028035 0 0 48 223 0 NA NA NA NA NA NA NA 3718 FUN_028033 446 496 376 933 256 NA NA NA NA NA NA NA 3719 FUN_028032 115 29 36 132 0 NA NA NA NA NA NA NA 3720 FUN_028031 181 286 68 392 191 NA NA NA NA NA NA NA 3721 FUN_040283 708 212 253 465 636 ptg000031l:6272246-6385468 P14381 1.07e-105 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 3722 FUN_010560 79 142 205 143 138 NA NA NA NA NA NA NA 3723 FUN_028039 631 607 673 420 774 ptg000021l:15166415-15175547 Q66J54 5.88e-23 Solute carrier family 22 member 6-A (Organic cation transporter 1-A) (Renal organic anion transporter 1-A) (ROAT1-A) Xenopus laevis (African clawed frog) NA GO:0009925; GO:0015075 3724 FUN_028038 2603 2252 2334 3398 1735 NA NA NA NA NA NA NA 3725 FUN_010561 775 612 371 594 327 NA NA NA NA NA NA NA 3726 FUN_010566 1407 973 541 795 845 NA NA NA NA NA NA NA 3727 FUN_010567 172 297 72 128 318 NA NA NA NA NA NA NA 3728 FUN_043434 177 181 498 192 121 ptg000047l:8463857-8465509 Q9Y5Z4 1.22e-22 Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005576; GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035578; GO:0035794; GO:0070062 3729 FUN_043435 12367 10500 7380 11060 15802 ptg000047l:8466906-8472176 Q9WU63 1.27e-28 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 3730 FUN_043435 12367 10500 7380 11060 15802 ptg000047l:8466906-8472176 Q9WU63 2.89e-26 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 3731 FUN_043436 9468 3833 11989 6475 9948 ptg000047l:8472415-8483783 Q9WU63 1.13e-26 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 3732 FUN_043437 6254 2293 11680 9104 11615 ptg000047l:8487383-8498577 Q9WU63 1.1e-26 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 3733 FUN_043437 6254 2293 11680 9104 11615 ptg000047l:8487383-8498577 Q9WU63 1.51e-25 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 3734 FUN_043430 0 14 7 30 21 ptg000047l:8432983-8436460 O42409 4.4e-74 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 3735 FUN_040284 1608 998 542 1413 1107 ptg000031l:6391143-6408390 Q91YK0 3.88e-22 Leucine-rich repeat-containing protein 49 (Tubulin polyglutamylase complex subunit 4) (PGs4) (p79) Mus musculus (Mouse) outer dynein arm assembly [GO:0036158] GO:0005737; GO:0005829; GO:0005874; GO:0034451; GO:0036158 3736 FUN_043432 372 390 368 353 515 NA NA NA NA NA NA NA 3737 FUN_043433 6141 7797 2393 2659 3576 ptg000047l:8459281-8461867 Q9WU63 9.24e-29 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 3738 FUN_010565 2071 1403 633 893 925 NA NA NA NA NA NA NA 3739 FUN_043438 1070 1026 502 650 829 NA NA NA NA NA NA NA 3740 FUN_043439 5219 4107 2160 3225 2380 NA NA NA NA NA NA NA 3741 FUN_041367 0 0 7 8 2 NA NA NA NA NA NA NA 3742 FUN_041364 0 18 28 39 0 NA NA NA NA NA NA NA 3743 FUN_041360 0 0 0 0 7 NA NA NA NA NA NA NA 3744 FUN_017780 573 766 684 1151 810 NA NA NA NA NA NA NA 3745 FUN_002275 0 0 0 0 9 NA NA NA NA NA NA NA 3746 FUN_002278 2 0 0 0 7 NA NA NA NA NA NA NA 3747 FUN_012058 119 0 54 571 111 NA NA NA NA NA NA NA 3748 FUN_012059 1624 1439 1156 1167 901 NA NA NA NA NA NA NA 3749 FUN_016001 1267 1109 628 2005 1979 NA NA NA NA NA NA NA 3750 FUN_012054 560 332 395 2623 569 NA NA NA NA NA NA NA 3751 FUN_012056 0 12 6 42 65 NA NA NA NA NA NA NA 3752 FUN_012057 124 89 101 174 81 ptg000008l:4641413-4688931 O00370 7.55e-50 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 3753 FUN_005268 4889 10461 7239 9446 2951 NA NA NA NA NA NA NA 3754 FUN_042479 32 8 110 13 284 NA NA NA NA NA NA NA 3755 FUN_042478 314 237 127 353 395 NA NA NA NA NA NA NA 3756 FUN_042477 106 82 26 146 42 NA NA NA NA NA NA NA 3757 FUN_042476 65 23 12 98 35 NA NA NA NA NA NA NA 3758 FUN_042475 0 0 17 0 0 NA NA NA NA NA NA NA 3759 FUN_042474 1 0 1 0 57 NA NA NA NA NA NA NA 3760 FUN_042473 4 18 0 16 7 NA NA NA NA NA NA NA 3761 FUN_042472 0 0 0 0 11 NA NA NA NA NA NA NA 3762 FUN_042471 51 1 48 127 119 NA NA NA NA NA NA NA 3763 FUN_042470 23 0 42 33 171 NA NA NA NA NA NA NA 3764 FUN_042020 4711 5292 3093 4767 3262 ptg000035l:9850316-9851984 Q0II91 5.8e-102 DnaJ homolog subfamily C member 21 Bos taurus (Bovine) NA GO:0003676; GO:0005730; GO:0005737; GO:0008270 3765 FUN_016007 1505 962 778 1335 1239 NA NA NA NA NA NA NA 3766 FUN_006264 213 47 92 1154 875 NA NA NA NA NA NA NA 3767 FUN_040181 68 5 0 0 0 NA NA NA NA NA NA NA 3768 FUN_040180 0 0 11 0 0 NA NA NA NA NA NA NA 3769 FUN_040182 12 8 0 11 43 NA NA NA NA NA NA NA 3770 FUN_040185 236 40 9 60 14 NA NA NA NA NA NA NA 3771 FUN_040184 22 4 0 4 7 NA NA NA NA NA NA NA 3772 FUN_040187 0 24 0 0 0 NA NA NA NA NA NA NA 3773 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 2.93e-69 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3774 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 2.93e-69 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3775 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 1.9e-67 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3776 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 1.9e-67 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3777 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 8.04e-56 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3778 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 1.48e-39 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3779 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 1.68e-39 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3780 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 1.95e-37 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3781 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 4.45e-31 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3782 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 4.76e-30 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3783 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 5.54e-30 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3784 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 2.47e-29 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3785 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 7.94e-28 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3786 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 5.67e-26 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3787 FUN_042025 4911 3475 3174 4748 3539 ptg000035l:9872550-9885773 P08775 1.85e-23 DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) Mus musculus (Mouse) cellular response to oxygen levels [GO:0071453]; DNA-templated transcription termination [GO:0006353]; positive regulation of RNA splicing [GO:0033120]; response to organic cyclic compound [GO:0014070]; transcription by RNA polymerase II [GO:0006366] GO:0000791; GO:0000974; GO:0001046; GO:0003677; GO:0003899; GO:0005634; GO:0005654; GO:0005665; GO:0005737; GO:0006353; GO:0006366; GO:0008022; GO:0014070; GO:0019900; GO:0031625; GO:0033120; GO:0046872; GO:0071453; GO:1990841 3788 FUN_042026 1598 1025 994 1831 1239 NA NA NA NA NA NA NA 3789 FUN_006261 106 181 43 144 199 NA NA NA NA NA NA NA 3790 FUN_032193 7429 6774 5363 4670 5791 NA NA NA NA NA NA NA 3791 FUN_032192 710 2224 431 444 337 NA NA NA NA NA NA NA 3792 FUN_032191 1605 1243 983 704 782 ptg000023l:29617120-29622781 Q0V9A9 9.83e-36 Endoribonuclease LACTB2 (Beta-lactamase-like protein 2) (EC 3.1.27.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003727; GO:0004521; GO:0005759; GO:0008270; GO:0090502 3793 FUN_032197 577 249 231 484 467 ptg000023l:29675469-29675904 F7E235 5.84e-24 Failed axon connections homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 3794 FUN_032196 425 543 264 337 501 NA NA NA NA NA NA NA 3795 FUN_032195 407 375 204 428 573 NA NA NA NA NA NA NA 3796 FUN_032194 11062 8944 6099 7370 7965 ptg000023l:29633805-29647581 P48506 9.8e-28 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 3797 FUN_032194 11062 8944 6099 7370 7965 ptg000023l:29633805-29647581 P48506 9.8e-28 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 3798 FUN_032194 11062 8944 6099 7370 7965 ptg000023l:29633805-29647581 P48506 9.8e-28 Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) Homo sapiens (Human) aging [GO:0007568]; blood vessel diameter maintenance [GO:0097746]; cell redox homeostasis [GO:0045454]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to follicle-stimulating hormone stimulus [GO:0071372]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to insulin stimulus [GO:0032869]; cellular response to mechanical stimulus [GO:0071260]; cellular response to thyroxine stimulus [GO:0097069]; cysteine metabolic process [GO:0006534]; glutamate metabolic process [GO:0006536]; glutathione biosynthetic process [GO:0006750]; L-ascorbic acid metabolic process [GO:0019852]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hepatic stellate cell activation [GO:2000490]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of mitochondrial depolarization [GO:0051900]; response to activity [GO:0014823]; response to arsenic-containing substance [GO:0046685]; response to cadmium ion [GO:0046686]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to human chorionic gonadotropin [GO:0044752]; response to interleukin-1 [GO:0070555]; response to nitrosative stress [GO:0051409]; response to nutrient [GO:0007584]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410] GO:0000287; GO:0004357; GO:0005524; GO:0005739; GO:0005829; GO:0006534; GO:0006536; GO:0006750; GO:0006979; GO:0007568; GO:0007584; GO:0009408; GO:0009410; GO:0009725; GO:0014823; GO:0016595; GO:0017109; GO:0019852; GO:0031397; GO:0032436; GO:0032869; GO:0035729; GO:0043066; GO:0043524; GO:0043531; GO:0044344; GO:0044752; GO:0044877; GO:0045454; GO:0045892; GO:0046685; GO:0046686; GO:0051409; GO:0051900; GO:0070555; GO:0071260; GO:0071333; GO:0071372; GO:0097069; GO:0097746; GO:1901029; GO:2000490; GO:2001237 3799 FUN_029816 101 48 74 15 52 NA NA NA NA NA NA NA 3800 FUN_029814 61 204 4 0 225 NA NA NA NA NA NA NA 3801 FUN_032198 60 34 19 19 77 NA NA NA NA NA NA NA 3802 FUN_029812 18 1 3 4 2 NA NA NA NA NA NA NA 3803 FUN_029811 5 7 3 3 5 NA NA NA NA NA NA NA 3804 FUN_043980 0 0 10 2 5 ptg000067l:71965-73521 P35067 2.69e-79 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 3805 FUN_032445 0 0 51 0 123 NA NA NA NA NA NA NA 3806 FUN_032444 6 1 16 0 0 NA NA NA NA NA NA NA 3807 FUN_032447 0 0 0 0 18 ptg000023l:32072665-32074740 E9Q236 2.09e-75 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 3808 FUN_000887 59 41 15 30 21 NA NA NA NA NA NA NA 3809 FUN_032441 21 40 31 0 27 NA NA NA NA NA NA NA 3810 FUN_032440 28 33 31 94 25 NA NA NA NA NA NA NA 3811 FUN_032443 677 346 236 419 370 NA NA NA NA NA NA NA 3812 FUN_032442 343 89 180 207 188 NA NA NA NA NA NA NA 3813 FUN_032449 20 0 0 0 0 NA NA NA NA NA NA NA 3814 FUN_032448 242 80 82 43 65 ptg000023l:32075153-32076354 E9Q236 3.65e-85 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 3815 FUN_023887 0 0 0 0 9 NA NA NA NA NA NA NA 3816 FUN_015885 8 1 7 0 10 NA NA NA NA NA NA NA 3817 FUN_023889 0 0 0 0 18 NA NA NA NA NA NA NA 3818 FUN_023888 35 0 14 45 97 NA NA NA NA NA NA NA 3819 FUN_008468 65 0 21 103 88 NA NA NA NA NA NA NA 3820 FUN_008469 276 250 157 208 270 ptg000002l:11986706-11988873 O35245 4.98e-34 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Mus musculus (Mouse) aorta development [GO:0035904]; branching involved in ureteric bud morphogenesis [GO:0001658]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell-cell signaling by wnt [GO:0198738]; cellular calcium ion homeostasis [GO:0006874]; cellular response to calcium ion [GO:0071277]; cellular response to cAMP [GO:0071320]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrostatic pressure [GO:0071464]; cellular response to osmotic stress [GO:0071470]; cilium organization [GO:0044782]; cytoplasmic sequestering of transcription factor [GO:0042994]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; embryonic placenta development [GO:0001892]; establishment of localization in cell [GO:0051649]; heart development [GO:0007507]; heart looping [GO:0001947]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; liver development [GO:0001889]; mesonephric duct development [GO:0072177]; metanephric ascending thin limb development [GO:0072218]; metanephric cortex development [GO:0072214]; metanephric cortical collecting duct development [GO:0072219]; metanephric distal tubule development [GO:0072235]; metanephric mesenchyme development [GO:0072075]; metanephric part of ureteric bud development [GO:0035502]; metanephric S-shaped body morphogenesis [GO:0072284]; metanephric smooth muscle tissue development [GO:0072208]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; neural tube development [GO:0021915]; placenta blood vessel development [GO:0060674]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of gene expression [GO:0010628]; positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031587]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of transcription by RNA polymerase II [GO:0045944]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of calcium ion import [GO:0090279]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; release of sequestered calcium ion into cytosol [GO:0051209]; renal artery morphogenesis [GO:0061441]; renal tubule morphogenesis [GO:0061333]; sodium ion transmembrane transport [GO:0035725]; spinal cord development [GO:0021510]; Wnt signaling pathway [GO:0016055] GO:0001658; GO:0001822; GO:0001889; GO:0001892; GO:0001947; GO:0002133; GO:0003127; GO:0005102; GO:0005244; GO:0005245; GO:0005248; GO:0005249; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005737; GO:0005783; GO:0005789; GO:0005794; GO:0005829; GO:0005886; GO:0005929; GO:0006816; GO:0006874; GO:0007204; GO:0007259; GO:0007368; GO:0007507; GO:0008092; GO:0009925; GO:0010628; GO:0015267; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0021510; GO:0021915; GO:0022843; GO:0030027; GO:0030659; GO:0031514; GO:0031587; GO:0034703; GO:0035502; GO:0035725; GO:0035904; GO:0036064; GO:0042127; GO:0042802; GO:0042803; GO:0042805; GO:0042994; GO:0043398; GO:0044325; GO:0044782; GO:0045180; GO:0045429; GO:0045737; GO:0045944; GO:0048763; GO:0050982; GO:0051117; GO:0051209; GO:0051219; GO:0051262; GO:0051289; GO:0051290; GO:0051371; GO:0051393; GO:0051649; GO:0051726; GO:0060170; GO:0060315; GO:0060674; GO:0061333; GO:0061441; GO:0070588; GO:0071277; GO:0071320; GO:0071464; GO:0071470; GO:0071498; GO:0071805; GO:0071910; GO:0072075; GO:0072177; GO:0072208; GO:0072214; GO:0072218; GO:0072219; GO:0072235; GO:0072284; GO:0072686; GO:0090279; GO:0097730; GO:0098553; GO:0098554; GO:0098662; GO:0198738; GO:2000134 3821 FUN_008462 0 1 0 1 7 NA NA NA NA NA NA NA 3822 FUN_008463 26 0 83 0 77 NA NA NA NA NA NA NA 3823 FUN_008460 35 53 83 13 165 NA NA NA NA NA NA NA 3824 FUN_008461 545 441 349 818 585 ptg000002l:11857196-11872981 Q7TN88 9.53e-42 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 3825 FUN_008461 545 441 349 818 585 ptg000002l:11857196-11872981 Q7TN88 4e-27 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 3826 FUN_008466 88 82 139 140 174 ptg000002l:11962180-11969222 Q7TN88 8.94e-35 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 3827 FUN_008467 0 0 20 42 180 NA NA NA NA NA NA NA 3828 FUN_008464 42 42 102 124 69 ptg000002l:11941814-11943428 Q4GZT3 4.32e-34 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 3829 FUN_008465 850 1672 624 1077 918 ptg000002l:11944312-11958991 Q7TN88 3.64e-44 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 3830 FUN_000259 156 1000 238 422 0 NA NA NA NA NA NA NA 3831 FUN_000250 116 135 95 31 83 NA NA NA NA NA NA NA 3832 FUN_000253 0 0 0 7 2 NA NA NA NA NA NA NA 3833 FUN_000252 1878 25972 953 5204 1706 NA NA NA NA NA NA NA 3834 FUN_000255 224 917 276 869 196 NA NA NA NA NA NA NA 3835 FUN_000254 24 2 2 5 131 NA NA NA NA NA NA NA 3836 FUN_000257 10 776 0 475 0 NA NA NA NA NA NA NA 3837 FUN_000256 14 34 13 0 50 NA NA NA NA NA NA NA 3838 FUN_016009 18 123 5 0 16 NA NA NA NA NA NA NA 3839 FUN_015062 1278 1238 303 819 369 NA NA NA NA NA NA NA 3840 FUN_016008 1188 1410 374 537 743 ptg000010l:477966-508678 P21328 7.66e-37 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 3841 FUN_018423 36 29 62 56 55 NA NA NA NA NA NA NA 3842 FUN_029108 36994 37138 23474 36804 23414 ptg000022l:8317031-8329577 P01122 6.18e-101 Ras-like GTP-binding protein RHO Aplysia californica (California sea hare) small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005886; GO:0007264 3843 FUN_029109 33649 31648 18483 25240 12490 ptg000022l:8330990-8331575 Q7T2E8 8.35e-122 Rho-related GTP-binding protein RhoA-C Danio rerio (Zebrafish) (Brachydanio rerio) actin filament organization [GO:0007015]; cell migration [GO:0016477]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; skeletal muscle satellite cell migration [GO:1902766]; small GTPase mediated signal transduction [GO:0007264]; wound healing, spreading of cells [GO:0044319] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0016477; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995; GO:0043005; GO:0044319; GO:1902766 3844 FUN_034033 62 7 28 37 33 NA NA NA NA NA NA NA 3845 FUN_029104 3913 6423 3511 9140 6550 NA NA NA NA NA NA NA 3846 FUN_029105 2404 1938 1425 2501 2471 ptg000022l:8290975-8307636 Q9VLT1 1.49e-74 Protein MON2 homolog Drosophila melanogaster (Fruit fly) actin cytoskeleton reorganization [GO:0031532]; pole plasm protein localization [GO:0007318]; protein transport [GO:0015031] GO:0005519; GO:0005768; GO:0005794; GO:0007318; GO:0015031; GO:0031532 3847 FUN_029105 2404 1938 1425 2501 2471 ptg000022l:8290975-8307636 Q9VLT1 1.49e-74 Protein MON2 homolog Drosophila melanogaster (Fruit fly) actin cytoskeleton reorganization [GO:0031532]; pole plasm protein localization [GO:0007318]; protein transport [GO:0015031] GO:0005519; GO:0005768; GO:0005794; GO:0007318; GO:0015031; GO:0031532 3848 FUN_029105 2404 1938 1425 2501 2471 ptg000022l:8290975-8307636 Q9VLT1 1.49e-74 Protein MON2 homolog Drosophila melanogaster (Fruit fly) actin cytoskeleton reorganization [GO:0031532]; pole plasm protein localization [GO:0007318]; protein transport [GO:0015031] GO:0005519; GO:0005768; GO:0005794; GO:0007318; GO:0015031; GO:0031532 3849 FUN_029105 2404 1938 1425 2501 2471 ptg000022l:8290975-8307636 Q9VLT1 2.51e-50 Protein MON2 homolog Drosophila melanogaster (Fruit fly) actin cytoskeleton reorganization [GO:0031532]; pole plasm protein localization [GO:0007318]; protein transport [GO:0015031] GO:0005519; GO:0005768; GO:0005794; GO:0007318; GO:0015031; GO:0031532 3850 FUN_029106 367 395 176 382 433 ptg000022l:8309035-8311898 Q8BH82 1.99e-81 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Mus musculus (Mouse) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; negative regulation of eating behavior [GO:1903999]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001659; GO:0004620; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0006644; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200; GO:1903999 3851 FUN_029107 9880 10119 10399 8353 5782 NA NA NA NA NA NA NA 3852 FUN_029100 327 160 320 259 1732 NA NA NA NA NA NA NA 3853 FUN_034030 331 59 168 242 218 ptg000024l:3972543-3975965 P52569 3.62e-91 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 3854 FUN_034030 331 59 168 242 218 ptg000024l:3972543-3975965 P52569 8.28e-21 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 3855 FUN_029102 0 5 12 34 10 NA NA NA NA NA NA NA 3856 FUN_029103 1577 2107 1854 6293 4650 NA NA NA NA NA NA NA 3857 FUN_033718 94 67 54 186 259 ptg000024l:662992-666727 Q29611 4.92e-23 Battenin (Protein CLN3) Canis lupus familiaris (Dog) (Canis familiaris) amyloid precursor protein catabolic process [GO:0042987]; autophagosome-lysosome fusion [GO:0061909]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; L-arginine transmembrane transport [GO:1903826]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; negative regulation of apoptotic process [GO:0043066]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of fibroblast migration [GO:0010762]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] GO:0000139; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007042; GO:0007611; GO:0008021; GO:0009992; GO:0010762; GO:0016020; GO:0031901; GO:0032228; GO:0035752; GO:0036359; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0044754; GO:0044857; GO:0045121; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1903826; GO:1905146; GO:1905162; GO:1905244; GO:2001288 3858 FUN_033719 2738 2568 1513 1683 1519 ptg000024l:668873-672990 Q8TBP0 1.37e-40 TBC1 domain family member 16 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; regulation of receptor recycling [GO:0001919] GO:0001919; GO:0005096; GO:0005769; GO:0005829; GO:0090630 3859 FUN_033712 1806 982 1159 1287 1287 NA NA NA NA NA NA NA 3860 FUN_033713 2355 3586 2031 1985 1181 ptg000024l:626688-631352 O55101 8.15e-25 Synaptogyrin-2 (Cellugyrin) Mus musculus (Mouse) protein targeting [GO:0006605]; regulated exocytosis [GO:0045055]; synaptic vesicle membrane organization [GO:0048499] GO:0006605; GO:0008021; GO:0016020; GO:0030672; GO:0031594; GO:0045055; GO:0048499 3861 FUN_033710 1898 2801 1101 1356 1217 NA NA NA NA NA NA NA 3862 FUN_033711 1908 1375 1364 1376 1115 NA NA NA NA NA NA NA 3863 FUN_033716 106 12 58 195 44 NA NA NA NA NA NA NA 3864 FUN_033717 2224 1200 1321 2222 1673 ptg000024l:657106-658696 Q8CHU3 4.35e-97 Epsin-2 (EPS-15-interacting protein 2) (Intersectin-EH-binding protein 2) (Ibp2) Mus musculus (Mouse) embryonic organ development [GO:0048568]; endocytosis [GO:0006897]; in utero embryonic development [GO:0001701]; negative regulation of sprouting angiogenesis [GO:1903671]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; Notch signaling pathway [GO:0007219]; positive regulation of Notch signaling pathway [GO:0045747]; regulation of endocytosis [GO:0030100] GO:0001701; GO:0005543; GO:0005768; GO:0005886; GO:0006897; GO:0007219; GO:0030100; GO:0030125; GO:0030128; GO:0030276; GO:0030948; GO:0043231; GO:0045747; GO:0048568; GO:1903671 3865 FUN_033714 482 412 371 512 280 NA NA NA NA NA NA NA 3866 FUN_033715 2217 990 939 1416 1348 NA NA NA NA NA NA NA 3867 FUN_039350 58 0 0 31 0 NA NA NA NA NA NA NA 3868 FUN_039351 59 6 0 39 0 NA NA NA NA NA NA NA 3869 FUN_039352 154 149 23 170 26 NA NA NA NA NA NA NA 3870 FUN_039353 63 88 62 72 53 ptg000029c:369717-372849 Q95SX7 1.25e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 3871 FUN_039354 3 28 14 0 6 NA NA NA NA NA NA NA 3872 FUN_034034 463 208 243 384 467 NA NA NA NA NA NA NA 3873 FUN_039356 5 91 7 0 2 NA NA NA NA NA NA NA 3874 FUN_039357 627 482 152 317 0 NA NA NA NA NA NA NA 3875 FUN_039358 525 1 9 544 2 ptg000029c:415923-417231 Q7RTR2 6.15e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3876 FUN_039358 525 1 9 544 2 ptg000029c:415923-417231 Q7RTR2 1.67e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3877 FUN_039358 525 1 9 544 2 ptg000029c:415923-417231 Q7RTR2 2.77e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3878 FUN_039358 525 1 9 544 2 ptg000029c:415923-417231 Q7RTR2 2.29e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3879 FUN_039358 525 1 9 544 2 ptg000029c:415923-417231 Q7RTR2 1.37e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3880 FUN_039358 525 1 9 544 2 ptg000029c:415923-417231 Q7RTR2 5.55e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 3881 FUN_039359 0 0 0 0 6 ptg000029c:433548-434567 Q9DGD1 4.18e-26 Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (EC 2.4.1.201) (N-acetylglucosaminyltransferase VI) (GnT-VI) Gallus gallus (Chicken) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0046872; GO:0047253 3882 FUN_034035 3 3 4 6 2 NA NA NA NA NA NA NA 3883 FUN_034038 0 0 0 0 10 NA NA NA NA NA NA NA 3884 FUN_018428 7611 6790 3972 8774 5197 NA NA NA NA NA NA NA 3885 FUN_010492 4 25 0 19 17 NA NA NA NA NA NA NA 3886 FUN_010493 2533 2143 467 134 159 ptg000006l:1379022-1419812 P10394 3.9e-49 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 3887 FUN_010494 4 2 2 2 18 NA NA NA NA NA NA NA 3888 FUN_010495 33 11 0 0 0 NA NA NA NA NA NA NA 3889 FUN_012388 2284 1750 980 1641 1131 NA NA NA NA NA NA NA 3890 FUN_012384 905 685 511 1029 1298 NA NA NA NA NA NA NA 3891 FUN_012385 1351 1443 487 675 604 ptg000008l:8513072-8521468 Q7LHG5 4.98e-86 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 3892 FUN_012380 541 485 178 478 416 NA NA NA NA NA NA NA 3893 FUN_012381 143 356 130 482 389 NA NA NA NA NA NA NA 3894 FUN_010728 4477 9561 2818 5555 2896 NA NA NA NA NA NA NA 3895 FUN_010729 186 116 31 181 118 NA NA NA NA NA NA NA 3896 FUN_010724 60 47 113 140 123 NA NA NA NA NA NA NA 3897 FUN_010725 987 600 561 992 1185 ptg000007l:2125212-2137741 Q61074 3.88e-25 Protein phosphatase 1G (EC 3.1.3.16) (Fibroblast growth factor-inducible protein 13) (FIN13) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) Mus musculus (Mouse) cell cycle [GO:0007049]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470]; regulation of cell cycle [GO:0051726] GO:0004721; GO:0004722; GO:0005634; GO:0005654; GO:0006470; GO:0007049; GO:0016020; GO:0017018; GO:0035970; GO:0046872; GO:0051726 3898 FUN_010726 1002 475 411 883 750 NA NA NA NA NA NA NA 3899 FUN_010727 1569 2234 705 2279 966 NA NA NA NA NA NA NA 3900 FUN_010720 9075 7709 4692 6145 4809 NA NA NA NA NA NA NA 3901 FUN_010721 26 100 45 102 66 NA NA NA NA NA NA NA 3902 FUN_010722 132 209 143 303 183 NA NA NA NA NA NA NA 3903 FUN_010723 558 370 386 728 743 NA NA NA NA NA NA NA 3904 FUN_012656 336 154 338 396 437 NA NA NA NA NA NA NA 3905 FUN_012657 2706 2192 2186 6518 4449 NA NA NA NA NA NA NA 3906 FUN_012654 1130 1057 423 1492 1011 ptg000008l:10952814-10956504 O43246 1.68e-92 Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4) Homo sapiens (Human) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0016020 3907 FUN_012655 923 800 427 1190 824 ptg000008l:10963010-10967123 P30825 1.17e-127 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1903352; GO:1903810; GO:1903826 3908 FUN_012652 47 24 77 66 63 NA NA NA NA NA NA NA 3909 FUN_012653 2465 1179 1052 7057 3367 NA NA NA NA NA NA NA 3910 FUN_012650 249 171 175 391 77 NA NA NA NA NA NA NA 3911 FUN_032628 6202 4309 3085 6107 3397 ptg000023l:34012860-34043757 Q9EQW7 2.72e-22 Kinesin-like protein KIF13A Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; endosome to lysosome transport [GO:0008333]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; microtubule-based movement [GO:0007018]; plus-end-directed vesicle transport along microtubule [GO:0072383]; regulation of cytokinesis [GO:0032465]; vesicle cargo loading [GO:0035459] GO:0000139; GO:0003777; GO:0005524; GO:0005813; GO:0005871; GO:0005874; GO:0006886; GO:0007018; GO:0007049; GO:0008017; GO:0008333; GO:0010008; GO:0016887; GO:0030496; GO:0032438; GO:0032465; GO:0032588; GO:0035459; GO:0043001; GO:0051301; GO:0072383 3912 FUN_012658 408 289 173 593 525 NA NA NA NA NA NA NA 3913 FUN_012659 1597 2665 2213 1421 1035 NA NA NA NA NA NA NA 3914 FUN_023928 4539 2644 2310 3850 3263 NA NA NA NA NA NA NA 3915 FUN_023929 31 0 0 0 15 ptg000018l:256854-260730 Q9PT84 5.76e-28 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel) (ERG) (Eag-related protein) (Ether-a-go-go-related protein) (Voltage-gated potassium channel subunit Kv11.2) Gallus gallus (Chicken) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005886; GO:0034765; GO:0042391; GO:0071805; GO:0086011 3916 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 3.45e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3917 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 1.56e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3918 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 1.37e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3919 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 3.85e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3920 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 7.47e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3921 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 1.2e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3922 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 1.24e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3923 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 8.55e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3924 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 9.79e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3925 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 6.35e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3926 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 1.8e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3927 FUN_038908 204 174 83 151 213 ptg000027l:12686862-12697773 Q96AY4 1.12e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3928 FUN_038907 65 156 31 89 67 ptg000027l:12670648-12673929 Q96AY4 9.83e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3929 FUN_038907 65 156 31 89 67 ptg000027l:12670648-12673929 Q96AY4 1.81e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3930 FUN_038907 65 156 31 89 67 ptg000027l:12670648-12673929 Q96AY4 1.32e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3931 FUN_038907 65 156 31 89 67 ptg000027l:12670648-12673929 Q96AY4 2.27e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3932 FUN_038904 0 14 2 7 29 NA NA NA NA NA NA NA 3933 FUN_038905 0 0 0 16 6 NA NA NA NA NA NA NA 3934 FUN_038902 2 0 0 0 40 NA NA NA NA NA NA NA 3935 FUN_038903 2001 4108 2072 2258 2565 NA NA NA NA NA NA NA 3936 FUN_038900 0 1 0 0 6 NA NA NA NA NA NA NA 3937 FUN_038901 986 655 508 647 793 NA NA NA NA NA NA NA 3938 FUN_038528 0 6 0 0 3 NA NA NA NA NA NA NA 3939 FUN_023925 3327 3640 1922 2517 1540 NA NA NA NA NA NA NA 3940 FUN_025100 2007 1528 1376 1721 1911 ptg000018l:13812690-13838254 Q8ND30 2.54e-22 Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) Homo sapiens (Human) neuromuscular junction development [GO:0007528]; synapse organization [GO:0050808] GO:0005615; GO:0005829; GO:0007528; GO:0042802; GO:0048786; GO:0050808 3941 FUN_022333 1442 686 907 1071 915 NA NA NA NA NA NA NA 3942 FUN_027991 60 7649 3148 3870 5459 NA NA NA NA NA NA NA 3943 FUN_027990 25 4365 2112 2074 1918 NA NA NA NA NA NA NA 3944 FUN_027993 35 4425 3482 2278 4707 NA NA NA NA NA NA NA 3945 FUN_027992 199 219 96 113 215 NA NA NA NA NA NA NA 3946 FUN_027995 12 1964 566 851 980 NA NA NA NA NA NA NA 3947 FUN_027994 5 1011 293 713 1540 NA NA NA NA NA NA NA 3948 FUN_027997 972 920 311 513 453 NA NA NA NA NA NA NA 3949 FUN_027996 8 636 371 346 767 NA NA NA NA NA NA NA 3950 FUN_027999 24507 34708 17859 28136 7098 NA NA NA NA NA NA NA 3951 FUN_027998 26 23 12 28 28 NA NA NA NA NA NA NA 3952 FUN_016519 23 40 19 51 34 ptg000011l:4300279-4306796 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3953 FUN_016519 23 40 19 51 34 ptg000011l:4300279-4306796 Q96AY4 1.61e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3954 FUN_016519 23 40 19 51 34 ptg000011l:4300279-4306796 Q96AY4 1.6e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3955 FUN_016519 23 40 19 51 34 ptg000011l:4300279-4306796 Q96AY4 4.05e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3956 FUN_025105 1 6 4 2 2 NA NA NA NA NA NA NA 3957 FUN_025107 168 162 74 15 111 NA NA NA NA NA NA NA 3958 FUN_014715 1801 872 957 1729 1577 NA NA NA NA NA NA NA 3959 FUN_014714 4759 2962 2064 3199 1239 NA NA NA NA NA NA NA 3960 FUN_014717 54 122 65 134 80 NA NA NA NA NA NA NA 3961 FUN_014716 2647 1749 1696 2695 2059 NA NA NA NA NA NA NA 3962 FUN_014711 706 496 201 351 196 NA NA NA NA NA NA NA 3963 FUN_014710 3523 2230 2329 3964 3415 NA NA NA NA NA NA NA 3964 FUN_014713 1985 1912 1227 1497 1571 NA NA NA NA NA NA NA 3965 FUN_014712 936 778 391 529 239 NA NA NA NA NA NA NA 3966 FUN_014719 60 63 24 54 97 NA NA NA NA NA NA NA 3967 FUN_014718 255 234 242 98 303 ptg000009l:2463013-2464866 F4KD68 1.18e-33 WAT1-related protein At5g45370 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005886; GO:0022857 3968 FUN_009788 815 517 394 1251 872 ptg000004l:11620603-11628413 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3969 FUN_009788 815 517 394 1251 872 ptg000004l:11620603-11628413 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3970 FUN_009788 815 517 394 1251 872 ptg000004l:11620603-11628413 Q96AY4 7.94e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3971 FUN_009788 815 517 394 1251 872 ptg000004l:11620603-11628413 Q96AY4 2.22e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3972 FUN_009788 815 517 394 1251 872 ptg000004l:11620603-11628413 Q96AY4 4.91e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3973 FUN_009789 0 0 20 0 12 NA NA NA NA NA NA NA 3974 FUN_009784 249 22 2 4 371 NA NA NA NA NA NA NA 3975 FUN_009785 97 56 5 9 82 NA NA NA NA NA NA NA 3976 FUN_009786 59 21 0 0 42 NA NA NA NA NA NA NA 3977 FUN_009787 6 53 6 43 21 NA NA NA NA NA NA NA 3978 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 2.4e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3979 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 2.4e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3980 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 7.81e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3981 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 7.81e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3982 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 2.78e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3983 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 2.78e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3984 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 5.64e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3985 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 7.27e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3986 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 1.87e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3987 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 8.29e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3988 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 8.29e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3989 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 2.62e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3990 FUN_009781 0 7 0 0 12 ptg000004l:11520059-11522495 Q96AY4 2.62e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3991 FUN_009782 270 137 181 281 253 ptg000004l:11536773-11541076 Q96AY4 3.1e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3992 FUN_009782 270 137 181 281 253 ptg000004l:11536773-11541076 Q96AY4 3.86e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3993 FUN_009782 270 137 181 281 253 ptg000004l:11536773-11541076 Q96AY4 4.06e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3994 FUN_009782 270 137 181 281 253 ptg000004l:11536773-11541076 Q96AY4 3.34e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3995 FUN_009782 270 137 181 281 253 ptg000004l:11536773-11541076 Q96AY4 1.31e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3996 FUN_009782 270 137 181 281 253 ptg000004l:11536773-11541076 Q96AY4 5.45e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 3997 FUN_009257 0 0 0 0 29 NA NA NA NA NA NA NA 3998 FUN_009254 0 0 0 2 19 NA NA NA NA NA NA NA 3999 FUN_009250 0 16 0 0 27 NA NA NA NA NA NA NA 4000 FUN_009251 63 138 43 39 53 ptg000004l:4570854-4575657 Q96AY4 1.77e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4001 FUN_009251 63 138 43 39 53 ptg000004l:4570854-4575657 Q96AY4 2.39e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4002 FUN_009251 63 138 43 39 53 ptg000004l:4570854-4575657 Q96AY4 2.32e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4003 FUN_009259 10 143 86 49 209 ptg000004l:4607200-4610929 Q96AY4 5.1e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4004 FUN_009259 10 143 86 49 209 ptg000004l:4607200-4610929 Q96AY4 8.89e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4005 FUN_009259 10 143 86 49 209 ptg000004l:4607200-4610929 Q96AY4 2.6e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4006 FUN_009259 10 143 86 49 209 ptg000004l:4607200-4610929 Q96AY4 8.65e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4007 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 9.22e-96 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4008 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 3.37e-94 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4009 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 1.58e-93 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4010 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 2.09e-92 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4011 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 7.43e-90 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4012 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 3.25e-88 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4013 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 1.2e-84 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4014 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 1.05e-76 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4015 FUN_026646 24 32 62 61 116 ptg000020l:11922120-11923137 Q5R5U3 1.84e-73 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 4016 FUN_026647 148 72 149 82 138 NA NA NA NA NA NA NA 4017 FUN_026644 196 160 0 0 0 NA NA NA NA NA NA NA 4018 FUN_026645 0 8 41 35 109 NA NA NA NA NA NA NA 4019 FUN_026643 0 25 0 0 0 NA NA NA NA NA NA NA 4020 FUN_026640 0 7 0 0 0 NA NA NA NA NA NA NA 4021 FUN_026641 0 0 0 6 0 NA NA NA NA NA NA NA 4022 FUN_015448 4806 2130 2398 2790 3340 NA NA NA NA NA NA NA 4023 FUN_025598 2286 1925 795 2126 2374 NA NA NA NA NA NA NA 4024 FUN_025593 0 62 0 11 11 NA NA NA NA NA NA NA 4025 FUN_015443 5146 1947 1808 2505 1667 ptg000009l:10228387-10234760 A7S4N4 3.39e-41 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 4026 FUN_015443 5146 1947 1808 2505 1667 ptg000009l:10228387-10234760 A7S4N4 6.99e-22 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 4027 FUN_015443 5146 1947 1808 2505 1667 ptg000009l:10228387-10234760 A7S4N4 2.13e-21 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 4028 FUN_025591 83 7 6 12 0 NA NA NA NA NA NA NA 4029 FUN_025597 38 49 23 109 36 NA NA NA NA NA NA NA 4030 FUN_025596 3831 3248 2480 1709 3177 ptg000019l:4800351-4808454 Q6P4Y0 2.7e-25 Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789; GO:0035598; GO:0046872; GO:0051539; GO:0061712 4031 FUN_025596 3831 3248 2480 1709 3177 ptg000019l:4800351-4808454 Q6P4Y0 2.09e-23 Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789; GO:0035598; GO:0046872; GO:0051539; GO:0061712 4032 FUN_025596 3831 3248 2480 1709 3177 ptg000019l:4800351-4808454 Q6P4Y0 1.12e-21 Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789; GO:0035598; GO:0046872; GO:0051539; GO:0061712 4033 FUN_025594 0 0 0 5 20 NA NA NA NA NA NA NA 4034 FUN_021030 0 161 0 260 0 NA NA NA NA NA NA NA 4035 FUN_021031 0 0 0 0 20 NA NA NA NA NA NA NA 4036 FUN_021032 12 0 134 67 31 NA NA NA NA NA NA NA 4037 FUN_021035 0 0 141 0 232 NA NA NA NA NA NA NA 4038 FUN_021036 7 1 23 0 25 NA NA NA NA NA NA NA 4039 FUN_021038 11 0 0 0 0 NA NA NA NA NA NA NA 4040 FUN_021039 8 0 7 15 5 NA NA NA NA NA NA NA 4041 FUN_018523 5601 8724 4163 6261 3592 ptg000012l:10401019-10403485 Q641Z6 2.36e-158 EH domain-containing protein 1 Rattus norvegicus (Rat) cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neuron projection development [GO:0010976]; protein homooligomerization [GO:0051260]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659] GO:0005509; GO:0005524; GO:0005525; GO:0005768; GO:0005769; GO:0005811; GO:0005886; GO:0006886; GO:0006897; GO:0010008; GO:0010886; GO:0010976; GO:0016197; GO:0020018; GO:0030139; GO:0031095; GO:0031175; GO:0031267; GO:0031901; GO:0032456; GO:0034383; GO:0042632; GO:0042802; GO:0043231; GO:0048471; GO:0051260; GO:0055038; GO:0060271; GO:0061512; GO:0072659; GO:1901741; GO:1990090; GO:2001137 4042 FUN_018523 5601 8724 4163 6261 3592 ptg000012l:10401019-10403485 Q641Z6 2.3e-59 EH domain-containing protein 1 Rattus norvegicus (Rat) cellular response to nerve growth factor stimulus [GO:1990090]; cholesterol homeostasis [GO:0042632]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; endocytosis [GO:0006897]; endosomal transport [GO:0016197]; intracellular protein transport [GO:0006886]; low-density lipoprotein particle clearance [GO:0034383]; neuron projection development [GO:0031175]; positive regulation of cholesterol storage [GO:0010886]; positive regulation of endocytic recycling [GO:2001137]; positive regulation of myoblast fusion [GO:1901741]; positive regulation of neuron projection development [GO:0010976]; protein homooligomerization [GO:0051260]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659] GO:0005509; GO:0005524; GO:0005525; GO:0005768; GO:0005769; GO:0005811; GO:0005886; GO:0006886; GO:0006897; GO:0010008; GO:0010886; GO:0010976; GO:0016197; GO:0020018; GO:0030139; GO:0031095; GO:0031175; GO:0031267; GO:0031901; GO:0032456; GO:0034383; GO:0042632; GO:0042802; GO:0043231; GO:0048471; GO:0051260; GO:0055038; GO:0060271; GO:0061512; GO:0072659; GO:1901741; GO:1990090; GO:2001137 4043 FUN_018711 0 0 0 26 6 NA NA NA NA NA NA NA 4044 FUN_018710 11 8 0 70 3 ptg000012l:12282101-12283852 Q9FNA2 7.97e-28 Polyamine oxidase 1 (AtPAO1) (EC 1.5.3.16) (EC 1.5.3.17) (N(1)-acetylpolyamine oxidase) (Spermine oxidase) Arabidopsis thaliana (Mouse-ear cress) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0005737; GO:0006598; GO:0016491; GO:0046208; GO:0046592; GO:0050660; GO:0052894; GO:0052895; GO:0052901; GO:0052902; GO:0052903; GO:0052904 4045 FUN_018713 22 0 0 0 0 NA NA NA NA NA NA NA 4046 FUN_018712 54 6 40 77 87 NA NA NA NA NA NA NA 4047 FUN_017967 1165 970 794 1826 1161 NA NA NA NA NA NA NA 4048 FUN_018714 205 98 181 0 205 NA NA NA NA NA NA NA 4049 FUN_017964 1982 1277 998 1829 1167 ptg000012l:2459484-2464069 Q33BP8 6.16e-29 Forkhead box protein N3 (Checkpoint suppressor 1) Sus scrofa (Pig) cell cycle [GO:0007049] GO:0003700; GO:0005634; GO:0007049; GO:0043565 4050 FUN_018719 22 14 0 139 142 NA NA NA NA NA NA NA 4051 FUN_018718 0 0 0 0 170 NA NA NA NA NA NA NA 4052 FUN_017969 82 29 0 14 0 NA NA NA NA NA NA NA 4053 FUN_017968 25 0 0 31 50 NA NA NA NA NA NA NA 4054 FUN_038296 2024 2370 1098 1708 1250 NA NA NA NA NA NA NA 4055 FUN_041786 8423 7762 4604 8160 6779 ptg000035l:7509077-7520047 Q01887 8.05e-27 Tyrosine-protein kinase RYK (EC 2.7.10.1) (Kinase VIK) (Met-related kinase) (NYK-R) Mus musculus (Mouse) axon extension involved in axon guidance [GO:0048846]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cell proliferation in midbrain [GO:0033278]; chemorepulsion of axon [GO:0061643]; chemorepulsion of dopaminergic neuron axon [GO:0036518]; commissural neuron axon guidance [GO:0071679]; corpus callosum development [GO:0022038]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative chemotaxis [GO:0050919]; negative regulation of axon extension involved in axon guidance [GO:0048843]; neuron differentiation [GO:0030182]; neuron projection development [GO:0031175]; planar cell polarity pathway involved in axon guidance [GO:1904938]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; skeletal system morphogenesis [GO:0048705]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953] GO:0004672; GO:0004888; GO:0005109; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0006468; GO:0007169; GO:0007409; GO:0007411; GO:0016020; GO:0016055; GO:0017147; GO:0022038; GO:0030182; GO:0031175; GO:0033278; GO:0033674; GO:0036518; GO:0042813; GO:0043235; GO:0043410; GO:0048705; GO:0048843; GO:0048846; GO:0050919; GO:0061643; GO:0071679; GO:1904938; GO:1904948; GO:1904953 4056 FUN_038294 4869 2167 1832 3708 2005 NA NA NA NA NA NA NA 4057 FUN_038295 1467 1663 779 1724 1144 ptg000027l:5365449-5366355 Q8IWE4 4.1e-80 DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) Homo sapiens (Human) negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein neddylation [GO:2000435]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein neddylation [GO:0045116]; regulation of cell cycle process [GO:0010564]; regulation of protein neddylation [GO:2000434]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225] GO:0000151; GO:0005634; GO:0005737; GO:0005886; GO:0010225; GO:0010332; GO:0010564; GO:0030308; GO:0031624; GO:0032182; GO:0043065; GO:0045116; GO:0048471; GO:0051443; GO:0097602; GO:2000134; GO:2000434; GO:2000435; GO:2000436 4058 FUN_038292 13818 11866 3096 12734 5453 ptg000027l:5342423-5343770 P43793 0 NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) glutamate biosynthetic process [GO:0006537] GO:0004354; GO:0005737; GO:0005829; GO:0006537 4059 FUN_038293 25 0 23 28 33 ptg000027l:5345764-5349918 Q9VBP3 4.01e-27 Poly [ADP-ribose] polymerase tankyrase (dTNKS) (EC 2.4.2.30) (Poly [ADP-ribose] polymerase) (Protein poly-ADP-ribosyltransferase tankyrase) (EC 2.4.2.-) Drosophila melanogaster (Fruit fly) positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of telomere capping [GO:1904355]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212] GO:0003950; GO:0005634; GO:0005737; GO:0016779; GO:0032436; GO:0045732; GO:0046872; GO:0070198; GO:0070212; GO:0090263; GO:1904355; GO:2000060 4060 FUN_038293 25 0 23 28 33 ptg000027l:5345764-5349918 Q9VBP3 1.56e-21 Poly [ADP-ribose] polymerase tankyrase (dTNKS) (EC 2.4.2.30) (Poly [ADP-ribose] polymerase) (Protein poly-ADP-ribosyltransferase tankyrase) (EC 2.4.2.-) Drosophila melanogaster (Fruit fly) positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of telomere capping [GO:1904355]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; protein localization to chromosome, telomeric region [GO:0070198]; protein poly-ADP-ribosylation [GO:0070212] GO:0003950; GO:0005634; GO:0005737; GO:0016779; GO:0032436; GO:0045732; GO:0046872; GO:0070198; GO:0070212; GO:0090263; GO:1904355; GO:2000060 4061 FUN_038290 350 214 298 182 341 NA NA NA NA NA NA NA 4062 FUN_038291 3059 3916 47 3836 513 ptg000027l:5337151-5339512 P94598 0 Glutamate dehydrogenase (GDH) (EC 1.4.1.3) (NAD(P)H-utilizing glutamate dehydrogenase) Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) glutamate biosynthetic process [GO:0006537] GO:0004352; GO:0004354; GO:0005829; GO:0006537 4063 FUN_038298 959 1123 784 1052 932 ptg000027l:5413860-5416170 Q6P8E9 5.7e-23 NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) mRNA splicing, via spliceosome [GO:0000398]; ribosome biogenesis [GO:0042254] GO:0000398; GO:0005634; GO:0005690; GO:0005730; GO:0030622; GO:0042254; GO:0046540; GO:0071005 4064 FUN_038299 1485 1190 430 1044 741 NA NA NA NA NA NA NA 4065 FUN_024648 18 27 0 0 0 NA NA NA NA NA NA NA 4066 FUN_024649 106 4 34 23 11 ptg000018l:9416309-9423849 Q7RTR2 3.18e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4067 FUN_024649 106 4 34 23 11 ptg000018l:9416309-9423849 Q7RTR2 2.91e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4068 FUN_024649 106 4 34 23 11 ptg000018l:9416309-9423849 Q7RTR2 1.03e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4069 FUN_024649 106 4 34 23 11 ptg000018l:9416309-9423849 Q7RTR2 8.64e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4070 FUN_024649 106 4 34 23 11 ptg000018l:9416309-9423849 Q7RTR2 1.08e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4071 FUN_024649 106 4 34 23 11 ptg000018l:9416309-9423849 Q7RTR2 9.27e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4072 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 1.37e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4073 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 7.81e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4074 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 1.78e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4075 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 1.18e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4076 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 2.07e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4077 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 2.83e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4078 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 3.76e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4079 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 4.95e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4080 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 4.3e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4081 FUN_024640 240 70 71 255 101 ptg000018l:9321475-9330603 Q7RTR2 2.01e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4082 FUN_024641 187 8 0 0 0 NA NA NA NA NA NA NA 4083 FUN_024642 573 601 842 494 3279 NA NA NA NA NA NA NA 4084 FUN_024643 6 10 18 10 26 NA NA NA NA NA NA NA 4085 FUN_024644 0 0 998 24 0 NA NA NA NA NA NA NA 4086 FUN_024645 47 0 0 700 0 NA NA NA NA NA NA NA 4087 FUN_024646 0 0 0 139 0 NA NA NA NA NA NA NA 4088 FUN_024647 0 0 2 30 0 NA NA NA NA NA NA NA 4089 FUN_038129 5076 3493 1388 1769 1752 NA NA NA NA NA NA NA 4090 FUN_030737 24 0 0 0 0 NA NA NA NA NA NA NA 4091 FUN_010562 6616 6731 1355 3026 1633 NA NA NA NA NA NA NA 4092 FUN_030733 15 0 0 0 7 NA NA NA NA NA NA NA 4093 FUN_038120 311 674 280 471 170 NA NA NA NA NA NA NA 4094 FUN_038122 247 121 181 253 396 NA NA NA NA NA NA NA 4095 FUN_038123 578 375 334 1128 1084 ptg000027l:2811923-2818800 Q93131 2.84e-85 Actin, cytoplasmic (EC 3.6.4.-) (BfCA1) [Cleaved into: Actin, cytoplasmic, N-terminally processed] Branchiostoma floridae (Florida lancelet) (Amphioxus) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 4096 FUN_021967 41 0 7 1 3 NA NA NA NA NA NA NA 4097 FUN_021965 0 19 0 6 21 NA NA NA NA NA NA NA 4098 FUN_021962 0 0 11 0 0 NA NA NA NA NA NA NA 4099 FUN_021969 6 0 0 1 0 NA NA NA NA NA NA NA 4100 FUN_001831 48 0 18 35 30 NA NA NA NA NA NA NA 4101 FUN_001837 0 0 0 0 80 NA NA NA NA NA NA NA 4102 FUN_001834 0 24 12 53 0 NA NA NA NA NA NA NA 4103 FUN_001835 181 32 66 338 207 NA NA NA NA NA NA NA 4104 FUN_001838 471 347 222 658 664 NA NA NA NA NA NA NA 4105 FUN_035528 1991 1802 1131 1650 1879 NA NA NA NA NA NA NA 4106 FUN_035523 418 391 184 588 446 NA NA NA NA NA NA NA 4107 FUN_035522 989 449 208 1186 318 NA NA NA NA NA NA NA 4108 FUN_035521 0 0 18 5 2 NA NA NA NA NA NA NA 4109 FUN_035520 50 6 0 20 12 NA NA NA NA NA NA NA 4110 FUN_035527 1286 1020 894 1510 1490 NA NA NA NA NA NA NA 4111 FUN_035526 149 81 0 0 53 NA NA NA NA NA NA NA 4112 FUN_035525 993 643 518 1236 812 ptg000025l:8622428-8627780 Q6DDZ9 6.83e-22 MTOR-associated protein MEAK7 (MEAK7) (TBC/LysM-associated domain-containing protein 1) (TLD domain-containing protein 1) Xenopus laevis (African clawed frog) positive regulation of protein localization to lysosome [GO:0150032]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; response to amino acid [GO:0043200]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; TOR signaling [GO:0031929] GO:0005737; GO:0005765; GO:0016020; GO:0030334; GO:0031667; GO:0031929; GO:0032868; GO:0042127; GO:0043200; GO:0150032 4113 FUN_035524 1780 245 367 805 2295 NA NA NA NA NA NA NA 4114 FUN_031068 26723 26170 13379 26387 15646 ptg000023l:16917503-16938710 Q0III9 8.17e-58 Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein) Bos taurus (Bovine) bone morphogenesis [GO:0060349]; focal adhesion assembly [GO:0048041]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of relaxation of muscle [GO:1901078]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883] GO:0005509; GO:0005903; GO:0005925; GO:0014728; GO:0014732; GO:0014883; GO:0014894; GO:0030018; GO:0031448; GO:0042802; GO:0044325; GO:0045820; GO:0048041; GO:0048633; GO:0048743; GO:0051015; GO:0060349; GO:0070885; GO:0090324; GO:0120163; GO:1900159; GO:1901078; GO:1904025 4115 FUN_031068 26723 26170 13379 26387 15646 ptg000023l:16917503-16938710 Q0III9 8.17e-58 Alpha-actinin-3 (Alpha-actinin skeletal muscle isoform 3) (F-actin cross-linking protein) Bos taurus (Bovine) bone morphogenesis [GO:0060349]; focal adhesion assembly [GO:0048041]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cold-induced thermogenesis [GO:0120163]; negative regulation of glycolytic process [GO:0045820]; negative regulation of oxidative phosphorylation [GO:0090324]; negative regulation of relaxation of muscle [GO:1901078]; positive regulation of bone mineralization involved in bone maturation [GO:1900159]; positive regulation of fast-twitch skeletal muscle fiber contraction [GO:0031448]; positive regulation of glucose catabolic process to lactate via pyruvate [GO:1904025]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of skeletal muscle tissue growth [GO:0048633]; regulation of the force of skeletal muscle contraction [GO:0014728]; response to denervation involved in regulation of muscle adaptation [GO:0014894]; skeletal muscle atrophy [GO:0014732]; transition between fast and slow fiber [GO:0014883] GO:0005509; GO:0005903; GO:0005925; GO:0014728; GO:0014732; GO:0014883; GO:0014894; GO:0030018; GO:0031448; GO:0042802; GO:0044325; GO:0045820; GO:0048041; GO:0048633; GO:0048743; GO:0051015; GO:0060349; GO:0070885; GO:0090324; GO:0120163; GO:1900159; GO:1901078; GO:1904025 4116 FUN_031069 0 0 2 1 36 NA NA NA NA NA NA NA 4117 FUN_031062 288 747 91 161 41 ptg000023l:16872454-16873628 P51824 8.76e-67 ADP-ribosylation factor 1 (EC 3.6.5.2) Solanum tuberosum (Potato) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0006886; GO:0016192 4118 FUN_031063 484 147 72 185 73 NA NA NA NA NA NA NA 4119 FUN_031060 0 0 0 0 7 NA NA NA NA NA NA NA 4120 FUN_031061 1099 1019 559 1259 783 NA NA NA NA NA NA NA 4121 FUN_031066 1096 2021 820 1646 1077 NA NA NA NA NA NA NA 4122 FUN_031067 480 142 213 333 324 NA NA NA NA NA NA NA 4123 FUN_031064 321 440 216 419 335 NA NA NA NA NA NA NA 4124 FUN_031065 267 539 134 134 84 ptg000023l:16884091-16885368 P51824 4.24e-67 ADP-ribosylation factor 1 (EC 3.6.5.2) Solanum tuberosum (Potato) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0006886; GO:0016192 4125 FUN_001784 5637 3093 2883 5178 4103 NA NA NA NA NA NA NA 4126 FUN_001785 43 31 33 35 37 NA NA NA NA NA NA NA 4127 FUN_001786 1932 1164 1176 2052 1260 ntLink_6:16021695-16038230 P25054 2.33e-112 Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5) Homo sapiens (Human) bicellular tight junction assembly [GO:0070830]; cell adhesion [GO:0007155]; cell fate specification [GO:0001708]; cell migration [GO:0016477]; cellular response to DNA damage stimulus [GO:0006974]; endocardial cushion morphogenesis [GO:0003203]; heart valve development [GO:0003170]; insulin receptor signaling pathway [GO:0008286]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of microtubule depolymerization [GO:0007026]; nervous system development [GO:0007399]; pattern specification process [GO:0007389]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell death [GO:0010942]; positive regulation of cell migration [GO:0030335]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to centrosome [GO:1904781]; positive regulation of pseudopodium assembly [GO:0031274]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein-containing complex assembly [GO:0065003]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cell differentiation [GO:0045595]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055] GO:0000281; GO:0000776; GO:0001708; GO:0003170; GO:0003203; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005813; GO:0005829; GO:0005874; GO:0005886; GO:0005912; GO:0005923; GO:0006974; GO:0007026; GO:0007094; GO:0007155; GO:0007389; GO:0007399; GO:0008013; GO:0008017; GO:0008285; GO:0008286; GO:0010942; GO:0016055; GO:0016328; GO:0016342; GO:0016477; GO:0019887; GO:0019901; GO:0030027; GO:0030335; GO:0030877; GO:0031274; GO:0031625; GO:0032587; GO:0032886; GO:0043065; GO:0043161; GO:0045295; GO:0045595; GO:0045732; GO:0045736; GO:0048471; GO:0051010; GO:0051988; GO:0065003; GO:0070830; GO:0070840; GO:0090090; GO:0120162; GO:1902807; GO:1904781; GO:1990909; GO:2000134 4128 FUN_001787 6158 5178 3667 6959 5538 NA NA NA NA NA NA NA 4129 FUN_001780 3089 2670 2005 1961 2374 NA NA NA NA NA NA NA 4130 FUN_001781 6175 3760 1864 5119 5075 ntLink_6:15954636-15971875 Q6V1X1 1.04e-24 Dipeptidyl peptidase 8 (DP8) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 1) (DPRP-1) (Dipeptidyl peptidase VIII) (DPP VIII) (Prolyl dipeptidase DPP8) Homo sapiens (Human) apoptotic process [GO:0006915]; immune response [GO:0006955]; proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006955; GO:0008236; GO:0008239 4131 FUN_001782 1959 1484 1765 1211 1749 NA NA NA NA NA NA NA 4132 FUN_001783 235 56 123 123 85 NA NA NA NA NA NA NA 4133 FUN_039653 0 0 0 0 6 NA NA NA NA NA NA NA 4134 FUN_039652 0 0 9 0 94 NA NA NA NA NA NA NA 4135 FUN_037969 982 504 673 480 898 ptg000027l:947063-974172 Q7Z442 1.39e-55 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 4136 FUN_037969 982 504 673 480 898 ptg000027l:947063-974172 Q7Z442 1.61e-36 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 4137 FUN_037968 6197 5573 2883 8496 6196 ptg000027l:940179-944044 Q24524 1.16e-66 Protein singed Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; antennal morphogenesis [GO:0048800]; cell migration [GO:0016477]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060] GO:0003779; GO:0005737; GO:0007163; GO:0008407; GO:0009913; GO:0015629; GO:0016358; GO:0016477; GO:0030034; GO:0030036; GO:0030674; GO:0035017; GO:0035099; GO:0035317; GO:0042060; GO:0043005; GO:0043025; GO:0046847; GO:0048477; GO:0048800; GO:0048812; GO:0051015; GO:0051017 4138 FUN_037968 6197 5573 2883 8496 6196 ptg000027l:940179-944044 Q24524 3.07e-21 Protein singed Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; actin filament bundle assembly [GO:0051017]; antennal morphogenesis [GO:0048800]; cell migration [GO:0016477]; chaeta morphogenesis [GO:0008407]; cuticle pattern formation [GO:0035017]; dendrite development [GO:0016358]; epidermal cell differentiation [GO:0009913]; establishment or maintenance of cell polarity [GO:0007163]; filopodium assembly [GO:0046847]; hemocyte migration [GO:0035099]; imaginal disc-derived wing hair organization [GO:0035317]; microvillar actin bundle assembly [GO:0030034]; neuron projection morphogenesis [GO:0048812]; oogenesis [GO:0048477]; wound healing [GO:0042060] GO:0003779; GO:0005737; GO:0007163; GO:0008407; GO:0009913; GO:0015629; GO:0016358; GO:0016477; GO:0030034; GO:0030036; GO:0030674; GO:0035017; GO:0035099; GO:0035317; GO:0042060; GO:0043005; GO:0043025; GO:0046847; GO:0048477; GO:0048800; GO:0048812; GO:0051015; GO:0051017 4139 FUN_037965 328 47 27 99 166 NA NA NA NA NA NA NA 4140 FUN_037964 12448 10127 4600 10863 8818 NA NA NA NA NA NA NA 4141 FUN_037967 227 266 412 205 265 NA NA NA NA NA NA NA 4142 FUN_037966 357 230 285 592 603 NA NA NA NA NA NA NA 4143 FUN_037961 51061 61205 29904 45793 44096 ptg000027l:879530-885138 Q3ZM03 5.35e-39 40S ribosomal protein SA (37 kDa laminin receptor precursor) (37LRP) (37/67 kDa laminin receptor) (LRP/LR) (67 kDa laminin receptor) (67LR) (Laminin receptor 1) (LamR) (Laminin-binding protein precursor p40) (LBP/p40) Xenopus laevis (African clawed frog) ribosomal small subunit assembly [GO:0000028]; translation [GO:0006412] GO:0000028; GO:0003735; GO:0005055; GO:0005634; GO:0005886; GO:0006412; GO:0022627; GO:0043236 4144 FUN_037960 897 575 645 466 872 ptg000027l:876142-878431 Q08CK1 1.93e-32 Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Danio rerio (Zebrafish) (Brachydanio rerio) innate immune response [GO:0045087]; regulation of oxidoreductase activity [GO:0051341]; regulation of protein complex stability [GO:0061635] GO:0005634; GO:0005737; GO:0005739; GO:0045087; GO:0051341; GO:0061635 4145 FUN_037963 797 480 506 808 828 ptg000027l:890828-894000 Q80YR4 3.33e-61 E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598) Mus musculus (Mouse) protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of translation [GO:0006417]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005829; GO:0006417; GO:0006513; GO:0016567; GO:0043022; GO:0046872; GO:0061630; GO:0072344; GO:1990116 4146 FUN_037962 197 290 138 272 384 NA NA NA NA NA NA NA 4147 FUN_027694 0 11 0 13 0 NA NA NA NA NA NA NA 4148 FUN_027695 0 0 0 22 0 NA NA NA NA NA NA NA 4149 FUN_027692 22 41 8 15 24 NA NA NA NA NA NA NA 4150 FUN_043361 0 0 0 15 25 NA NA NA NA NA NA NA 4151 FUN_043147 8015 9225 4183 6543 3995 NA NA NA NA NA NA NA 4152 FUN_027528 16 9 1 38 35 NA NA NA NA NA NA NA 4153 FUN_027529 867 1352 334 933 913 NA NA NA NA NA NA NA 4154 FUN_027521 0 0 0 2 8 NA NA NA NA NA NA NA 4155 FUN_027524 0 0 0 0 23 NA NA NA NA NA NA NA 4156 FUN_027525 0 0 14 0 31 NA NA NA NA NA NA NA 4157 FUN_027527 0 0 0 130 204 NA NA NA NA NA NA NA 4158 FUN_032689 512 858 409 752 779 NA NA NA NA NA NA NA 4159 FUN_037389 7 52 0 44 17 NA NA NA NA NA NA NA 4160 FUN_037381 28 33 8 26 65 NA NA NA NA NA NA NA 4161 FUN_037380 0 18 4 0 0 NA NA NA NA NA NA NA 4162 FUN_037383 721 516 324 480 312 ptg000026l:9821067-9824379 Q99MU3 4.54e-121 Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1) Mus musculus (Mouse) adenosine to inosine editing [GO:0006382]; apoptotic process [GO:0006915]; base conversion or substitution editing [GO:0016553]; cellular response to virus [GO:0098586]; defense response to virus [GO:0051607]; definitive hemopoiesis [GO:0060216]; erythrocyte differentiation [GO:0030218]; hematopoietic progenitor cell differentiation [GO:0002244]; hematopoietic stem cell homeostasis [GO:0061484]; hepatocyte apoptotic process [GO:0097284]; innate immune response [GO:0045087]; miRNA processing [GO:0035196]; mRNA processing [GO:0006397]; negative regulation of hepatocyte apoptotic process [GO:1903944]; negative regulation of post-transcriptional gene silencing by RNA [GO:1900369]; negative regulation of protein kinase activity by regulation of protein phosphorylation [GO:0044387]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; osteoblast differentiation [GO:0001649]; positive regulation of viral genome replication [GO:0045070]; pre-miRNA processing [GO:0031054]; protein export from nucleus [GO:0006611]; protein import into nucleus [GO:0006606]; response to interferon-alpha [GO:0035455]; response to virus [GO:0009615]; RISC complex assembly [GO:0070922]; RNA processing [GO:0006396]; somatic diversification of immune receptors via somatic mutation [GO:0002566] GO:0001649; GO:0002244; GO:0002566; GO:0003692; GO:0003725; GO:0003726; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006382; GO:0006396; GO:0006397; GO:0006606; GO:0006611; GO:0006915; GO:0008251; GO:0009615; GO:0016553; GO:0016607; GO:0030218; GO:0031054; GO:0035196; GO:0035455; GO:0044387; GO:0044530; GO:0045070; GO:0045087; GO:0046872; GO:0051607; GO:0060216; GO:0060339; GO:0061484; GO:0070922; GO:0097284; GO:0098586; GO:1900369; GO:1903944 4163 FUN_037382 1616 742 653 1864 1422 NA NA NA NA NA NA NA 4164 FUN_037385 2567 1936 1299 2314 1999 ptg000026l:9839084-9841657 Q15459 4.08e-24 Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) Homo sapiens (Human) mRNA 3'-splice site recognition [GO:0000389]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; U2-type prespliceosome assembly [GO:1903241] GO:0000389; GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0006397; GO:0016607; GO:0045292; GO:0071004; GO:0071005; GO:0071013; GO:1903241 4165 FUN_037384 490 332 273 287 194 NA NA NA NA NA NA NA 4166 FUN_037387 0 0 0 0 10 NA NA NA NA NA NA NA 4167 FUN_037386 425 278 194 420 280 NA NA NA NA NA NA NA 4168 FUN_042093 28 65 0 29 40 ptg000036l:498347-501665 Q5ZM55 4e-126 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Gallus gallus (Chicken) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 4169 FUN_013379 793 618 749 872 622 NA NA NA NA NA NA NA 4170 FUN_013376 6454 6157 2975 4285 1998 NA NA NA NA NA NA NA 4171 FUN_005208 0 0 4 0 19 NA NA NA NA NA NA NA 4172 FUN_013377 1823 1908 943 1857 2024 NA NA NA NA NA NA NA 4173 FUN_005205 0 20 0 26 35 NA NA NA NA NA NA NA 4174 FUN_005204 92 204 85 405 597 NA NA NA NA NA NA NA 4175 FUN_005206 118 12 150 9 120 NA NA NA NA NA NA NA 4176 FUN_005201 55 0 107 97 46 NA NA NA NA NA NA NA 4177 FUN_005200 601 296 377 736 851 ntLink_8:32700053-32701205 Q6P3P5 1.63e-26 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0008457; GO:0047256 4178 FUN_005202 273 118 0 172 84 NA NA NA NA NA NA NA 4179 FUN_004552 539 260 248 242 392 ntLink_8:24296394-24298924 Q9Y5X5 6.67e-35 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 4180 FUN_004553 1037 700 698 811 697 NA NA NA NA NA NA NA 4181 FUN_004550 22 14 18 48 22 ntLink_8:24275304-24278718 Q9EQD2 1.96e-29 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 4182 FUN_004551 0 0 2 5 18 NA NA NA NA NA NA NA 4183 FUN_004556 1989 1378 1089 1159 1566 ntLink_8:24322745-24328161 P20911 5.16e-30 Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (40 kDa protein kinase) (CDC2/CDK2,4-activating kinase) (Cell division protein kinase 7) (P40 MO15) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0006468; GO:0008353; GO:0051301; GO:0051321; GO:0070985; GO:0106310 4184 FUN_004556 1989 1378 1089 1159 1566 ntLink_8:24322745-24328161 P20911 5.16e-30 Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (40 kDa protein kinase) (CDC2/CDK2,4-activating kinase) (Cell division protein kinase 7) (P40 MO15) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0006468; GO:0008353; GO:0051301; GO:0051321; GO:0070985; GO:0106310 4185 FUN_004557 871 834 897 876 704 NA NA NA NA NA NA NA 4186 FUN_004554 4356 3139 2117 2698 2672 NA NA NA NA NA NA NA 4187 FUN_004555 23 0 0 29 23 NA NA NA NA NA NA NA 4188 FUN_042099 243 368 429 223 450 ptg000036l:552613-556400 Q09143 3.05e-102 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor) (Ecotropic retrovirus receptor) (ERR) (EcoR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Mus musculus (Mouse) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; regulation of TOR signaling [GO:0032006] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032006; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:1903352; GO:1903810; GO:1903826 4189 FUN_004558 11 12 2 2 17 NA NA NA NA NA NA NA 4190 FUN_004559 499 476 444 371 373 NA NA NA NA NA NA NA 4191 FUN_042098 21 277 106 0 60 NA NA NA NA NA NA NA 4192 FUN_037033 35 0 0 0 15 NA NA NA NA NA NA NA 4193 FUN_037030 6 683 0 0 612 NA NA NA NA NA NA NA 4194 FUN_037037 6 16 0 27 9 NA NA NA NA NA NA NA 4195 FUN_037036 49 6 8 0 0 NA NA NA NA NA NA NA 4196 FUN_037035 871 646 370 1068 123 ptg000026l:4809745-4815401 P0CI65 1.63e-44 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4197 FUN_037035 871 646 370 1068 123 ptg000026l:4809745-4815401 P0CI65 2.14e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 4198 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 1.61e-52 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4199 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 4.14e-48 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4200 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 4.4e-46 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4201 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 5.3e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4202 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 6.4e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4203 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 7.4e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4204 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 4.08e-41 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4205 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 1.47e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4206 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 1.66e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4207 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 1.29e-22 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4208 FUN_037039 1111 793 581 798 112 ptg000026l:4894664-4900060 Q7Z494 5.57e-22 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 4209 FUN_037038 18 0 20 14 0 ptg000026l:4860012-4863682 P14381 1.34e-67 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 4210 FUN_032609 1539 891 677 1076 1333 NA NA NA NA NA NA NA 4211 FUN_032608 10 17 35 3 19 NA NA NA NA NA NA NA 4212 FUN_032603 649 267 267 382 509 ptg000023l:33791191-33796885 P37967 3.43e-29 Para-nitrobenzyl esterase (EC 3.1.1.-) (Intracellular esterase B) (PNB carboxy-esterase) (PNBCE) Bacillus subtilis (strain 168) NA GO:0004104 4213 FUN_032602 13484 5134 3578 5371 4418 NA NA NA NA NA NA NA 4214 FUN_032601 339 20 19 19 307 NA NA NA NA NA NA NA 4215 FUN_032600 305 0 0 0 16 NA NA NA NA NA NA NA 4216 FUN_032607 2806 2072 2425 2004 2733 NA NA NA NA NA NA NA 4217 FUN_032606 416 229 289 259 202 NA NA NA NA NA NA NA 4218 FUN_032605 1323 716 973 1200 1118 ptg000023l:33805674-33853610 Q9JKK8 1.58e-46 Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; chromosome organization [GO:0051276]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; embryo implantation [GO:0007566]; establishment of RNA localization to telomere [GO:0097694]; negative regulation of DNA replication [GO:0008156]; nucleobase-containing compound metabolic process [GO:0006139]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043517]; positive regulation of telomerase catalytic core complex assembly [GO:1904884]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein localization to chromosome, telomeric region [GO:0070198]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair [GO:2000779]; regulation of protein binding [GO:0043393]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; telomere maintenance [GO:0000723] GO:0000077; GO:0000723; GO:0001673; GO:0001741; GO:0003677; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005794; GO:0006139; GO:0006281; GO:0006468; GO:0006974; GO:0007566; GO:0008156; GO:0016605; GO:0018105; GO:0031297; GO:0032212; GO:0032405; GO:0032407; GO:0034644; GO:0043393; GO:0043517; GO:0046777; GO:0051276; GO:0070198; GO:0070310; GO:0071480; GO:0090399; GO:0097694; GO:0106310; GO:1904884; GO:2000779 4219 FUN_032604 46 6 29 55 211 ptg000023l:33797752-33799807 O75346 7.01e-67 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 4220 FUN_032604 46 6 29 55 211 ptg000023l:33797752-33799807 O75346 2.09e-62 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 4221 FUN_032604 46 6 29 55 211 ptg000023l:33797752-33799807 O75346 1.48e-61 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 4222 FUN_032604 46 6 29 55 211 ptg000023l:33797752-33799807 O75346 4.82e-51 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 4223 FUN_032604 46 6 29 55 211 ptg000023l:33797752-33799807 O75346 2.35e-33 Zinc finger protein 253 (Bone marrow zinc finger 1) (BMZF-1) (Zinc finger protein 411) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0045892; GO:0046872 4224 FUN_023097 378 362 166 330 98 ptg000017l:3595476-3597977 Q9CYL5 2.98e-31 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 4225 FUN_034609 12 12 0 20 19 NA NA NA NA NA NA NA 4226 FUN_034605 6802 4241 2628 5054 2458 NA NA NA NA NA NA NA 4227 FUN_034604 74130 64411 29366 61067 26943 ptg000024l:9532078-9533556 Q13887 1.74e-24 Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) Homo sapiens (Human) angiogenesis [GO:0001525]; cell-cell signaling via exosome [GO:0099156]; cellular response to leukemia inhibitory factor [GO:1990830]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; myotube differentiation involved in skeletal muscle regeneration [GO:0014908]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by transcription factor localization [GO:0061586]; regulation of microvillus assembly [GO:0032534]; regulation of transcription by RNA polymerase II [GO:0006357]; satellite cell activation involved in skeletal muscle regeneration [GO:0014901]; skeletal muscle satellite cell differentiation [GO:0014816] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005654; GO:0005667; GO:0005794; GO:0006357; GO:0014816; GO:0014901; GO:0014908; GO:0030033; GO:0032534; GO:0043231; GO:0043426; GO:0045600; GO:0045944; GO:0046872; GO:0060576; GO:0061586; GO:0099156; GO:1902895; GO:1990830; GO:1990837 4228 FUN_034607 277 166 199 296 402 ptg000024l:9549438-9550758 Q6PF45 5.73e-57 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 4229 FUN_034606 553 528 170 967 638 NA NA NA NA NA NA NA 4230 FUN_034601 38 1 0 9 4 NA NA NA NA NA NA NA 4231 FUN_036818 159 30 40 217 161 ptg000026l:2240119-2247701 Q17RP2 4.58e-56 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 4232 FUN_034603 47 53 33 84 59 NA NA NA NA NA NA NA 4233 FUN_034602 0 0 26 17 0 NA NA NA NA NA NA NA 4234 FUN_041919 241 294 164 131 96 NA NA NA NA NA NA NA 4235 FUN_041918 0 17 9 1 4 NA NA NA NA NA NA NA 4236 FUN_041914 145 0 84 109 93 ptg000035l:8828182-8835012 Q8IV77 3.84e-43 Cyclic nucleotide-gated cation channel alpha-4 (Cyclic nucleotide-gated channel alpha-4) (CNG channel alpha-4) (CNG-4) (CNG4) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] GO:0005222; GO:0005223; GO:0005886; GO:0007608; GO:0017071; GO:0030552; GO:0030553; GO:0030660; GO:0044877; GO:0050896; GO:0060170; GO:0098655 4237 FUN_041917 1106 463 585 801 414 NA NA NA NA NA NA NA 4238 FUN_041916 164 101 109 89 99 ptg000035l:8841963-8847139 Q16281 9.41e-110 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 4239 FUN_041916 164 101 109 89 99 ptg000035l:8841963-8847139 Q16281 9.41e-110 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 4240 FUN_041916 164 101 109 89 99 ptg000035l:8841963-8847139 Q16281 2.95e-32 Cyclic nucleotide-gated cation channel alpha-3 (Cone photoreceptor cGMP-gated channel subunit alpha) (Cyclic nucleotide-gated channel alpha-3) (CNG channel alpha-3) (CNG-3) (CNG3) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; inorganic cation import across plasma membrane [GO:0098659]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to magnesium ion [GO:0032026]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0005222; GO:0005223; GO:0005737; GO:0005886; GO:0006812; GO:0007165; GO:0007601; GO:0008022; GO:0015276; GO:0017071; GO:0030425; GO:0030553; GO:0031960; GO:0032026; GO:0043194; GO:0043204; GO:0044877; GO:0051591; GO:0097386; GO:0098655; GO:0098659; GO:1902495 4241 FUN_041911 625 399 517 470 579 ptg000035l:8812294-8815201 B0BN49 2.71e-26 RNA-binding motif protein, X-linked 2 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005686; GO:0071005; GO:0071011 4242 FUN_041911 625 399 517 470 579 ptg000035l:8812294-8815201 B0BN49 2.71e-26 RNA-binding motif protein, X-linked 2 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0005686; GO:0071005; GO:0071011 4243 FUN_041910 1221 2029 914 1090 948 ptg000035l:8810552-8812085 Q9DB94 1.56e-36 WD repeat-containing protein 53 Mus musculus (Mouse) NA NA 4244 FUN_041913 214 64 80 115 101 ptg000035l:8823682-8824966 P16388 1.32e-86 Potassium voltage-gated channel subfamily A member 1 (MBK1) (MKI) (Voltage-gated potassium channel subunit Kv1.1) Mus musculus (Mouse) axon development [GO:0061564]; brain development [GO:0007420]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005783; GO:0005829; GO:0005886; GO:0006937; GO:0007405; GO:0007420; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030424; GO:0030425; GO:0031410; GO:0033270; GO:0034705; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 4245 FUN_041912 3835 4030 2365 2778 1922 NA NA NA NA NA NA NA 4246 FUN_001003 406 375 285 217 56 NA NA NA NA NA NA NA 4247 FUN_001002 0 0 3 29 0 NA NA NA NA NA NA NA 4248 FUN_001001 8147 3458 1405 4778 3311 NA NA NA NA NA NA NA 4249 FUN_001000 534 420 150 290 77 NA NA NA NA NA NA NA 4250 FUN_001007 1098 734 406 946 462 NA NA NA NA NA NA NA 4251 FUN_001006 1214 583 746 1081 1090 ntLink_6:7099579-7126307 Q78IS1 6.92e-33 Transmembrane emp24 domain-containing protein 3 (p24 family protein gamma-4) (p24gamma4) Mus musculus (Mouse) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0030126; GO:0030134; GO:0032580; GO:0033116 4252 FUN_001005 3339 3173 1400 1297 382 NA NA NA NA NA NA NA 4253 FUN_001004 420 579 333 560 294 NA NA NA NA NA NA NA 4254 FUN_001009 1523 1397 1741 2021 807 NA NA NA NA NA NA NA 4255 FUN_001008 817 291 659 568 454 NA NA NA NA NA NA NA 4256 FUN_035950 0 0 0 20 0 NA NA NA NA NA NA NA 4257 FUN_035957 0 0 4 0 34 NA NA NA NA NA NA NA 4258 FUN_028779 0 29 56 6 8 NA NA NA NA NA NA NA 4259 FUN_029225 843 78 212 183 35 NA NA NA NA NA NA NA 4260 FUN_029224 137 57 30 42 16 NA NA NA NA NA NA NA 4261 FUN_029227 51 70 45 68 142 ptg000022l:9405327-9407207 Q9BYN7 1.23e-37 Zinc finger protein 341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0001216; GO:0003677; GO:0005634; GO:0006355; GO:0046872 4262 FUN_029226 244 90 94 168 11 NA NA NA NA NA NA NA 4263 FUN_029221 242 39 70 90 139 ptg000022l:9378369-9382140 Q9BYN7 1.53e-36 Zinc finger protein 341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0001216; GO:0003677; GO:0005634; GO:0006355; GO:0046872 4264 FUN_029220 800 929 750 1832 879 NA NA NA NA NA NA NA 4265 FUN_029223 33 37 0 20 17 NA NA NA NA NA NA NA 4266 FUN_029222 6 12 12 19 34 NA NA NA NA NA NA NA 4267 FUN_005106 859 494 740 748 917 NA NA NA NA NA NA NA 4268 FUN_030108 0 0 0 15 12 NA NA NA NA NA NA NA 4269 FUN_041701 1145 723 620 1153 961 NA NA NA NA NA NA NA 4270 FUN_044238 3 0 10 1 83 NA NA NA NA NA NA NA 4271 FUN_005104 227 117 79 145 113 NA NA NA NA NA NA NA 4272 FUN_044237 1 4 4 3 31 NA NA NA NA NA NA NA 4273 FUN_041703 6920 6189 4302 5638 3086 ptg000035l:6688298-6695525 O08730 8.9e-43 Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186) Rattus norvegicus (Rat) glycogen biosynthetic process [GO:0005978] GO:0005536; GO:0005978; GO:0008466; GO:0016757; GO:0030145; GO:0042803; GO:0102751 4274 FUN_030107 7 0 0 0 0 NA NA NA NA NA NA NA 4275 FUN_041704 454 117 137 342 268 ptg000035l:6697742-6699263 Q9UJA9 4.99e-83 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 4276 FUN_005103 501 169 191 470 279 NA NA NA NA NA NA NA 4277 FUN_041706 514 209 149 398 760 NA NA NA NA NA NA NA 4278 FUN_044233 2 6 7 2 54 NA NA NA NA NA NA NA 4279 FUN_005101 207 143 158 255 370 NA NA NA NA NA NA NA 4280 FUN_036528 0 0 0 11 16 NA NA NA NA NA NA NA 4281 FUN_044232 51 188 78 134 425 NA NA NA NA NA NA NA 4282 FUN_012414 44 44 29 44 116 ptg000008l:8753193-8756868 A4QNG3 4.9e-24 Transcription factor Sox-14 (SRY (sex determining region Y)-box 14) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399] GO:0000122; GO:0005634; GO:0007399; GO:0043565; GO:0045892 4283 FUN_012415 191 205 90 117 196 NA NA NA NA NA NA NA 4284 FUN_012417 126 41 37 75 81 NA NA NA NA NA NA NA 4285 FUN_029593 100 8 25 65 41 NA NA NA NA NA NA NA 4286 FUN_044231 9 15 17 21 50 NA NA NA NA NA NA NA 4287 FUN_012412 18 509 101 242 134 ptg000008l:8742059-8744196 Q9QYS2 8.48e-22 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 4288 FUN_012413 333 242 165 266 249 NA NA NA NA NA NA NA 4289 FUN_006842 16363 24396 9328 14875 5709 NA NA NA NA NA NA NA 4290 FUN_006843 5342 4106 3063 9839 6305 NA NA NA NA NA NA NA 4291 FUN_006840 2789 5565 4275 3638 6166 NA NA NA NA NA NA NA 4292 FUN_006841 14 73 119 89 270 ptg000001l:17282189-17285318 Q0V8T4 8.27e-30 Contactin-associated protein like 5-3 (Cell recognition molecule Caspr5-3) (Cell recognition molecule Caspr5c) (Contactin-associated protein-like 5c) Rattus norvegicus (Rat) cell adhesion [GO:0007155] GO:0005509; GO:0007155; GO:0016020 4293 FUN_012418 1134 702 599 1227 1406 ptg000008l:8786575-8793209 Q7TQE6 4.21e-38 Macoilin (Brain-specific adapter protein C61) (Macoilin-1) (Transmembrane protein 57) Mus musculus (Mouse) brain development [GO:0007420]; chemotaxis [GO:0006935]; neuronal signal transduction [GO:0023041] GO:0005634; GO:0006935; GO:0007420; GO:0008017; GO:0023041; GO:0030424; GO:0030867; GO:0031965; GO:0043005; GO:0044306; GO:0045202 4294 FUN_012418 1134 702 599 1227 1406 ptg000008l:8786575-8793209 Q7TQE6 6.93e-21 Macoilin (Brain-specific adapter protein C61) (Macoilin-1) (Transmembrane protein 57) Mus musculus (Mouse) brain development [GO:0007420]; chemotaxis [GO:0006935]; neuronal signal transduction [GO:0023041] GO:0005634; GO:0006935; GO:0007420; GO:0008017; GO:0023041; GO:0030424; GO:0030867; GO:0031965; GO:0043005; GO:0044306; GO:0045202 4295 FUN_012418 1134 702 599 1227 1406 ptg000008l:8786575-8793209 Q7TQE6 6.93e-21 Macoilin (Brain-specific adapter protein C61) (Macoilin-1) (Transmembrane protein 57) Mus musculus (Mouse) brain development [GO:0007420]; chemotaxis [GO:0006935]; neuronal signal transduction [GO:0023041] GO:0005634; GO:0006935; GO:0007420; GO:0008017; GO:0023041; GO:0030424; GO:0030867; GO:0031965; GO:0043005; GO:0044306; GO:0045202 4296 FUN_006847 7003 5570 3220 5819 5895 NA NA NA NA NA NA NA 4297 FUN_029598 287 86 6 53 66 ptg000023l:3592993-3600165 E7FAM5 1.67e-53 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 4298 FUN_016564 20 26 32 58 46 ptg000011l:4782188-4789193 Q96AY4 8.67e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4299 FUN_016564 20 26 32 58 46 ptg000011l:4782188-4789193 Q96AY4 8.06e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4300 FUN_016564 20 26 32 58 46 ptg000011l:4782188-4789193 Q96AY4 3.13e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4301 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4302 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 2.43e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4303 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 6.66e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4304 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 4.18e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4305 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 2.38e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4306 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 1.12e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4307 FUN_016566 126 59 66 168 93 ptg000011l:4808092-4812728 Q96AY4 1.67e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4308 FUN_016562 65 125 72 83 129 ptg000011l:4760119-4765259 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4309 FUN_016562 65 125 72 83 129 ptg000011l:4760119-4765259 Q96AY4 7.18e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4310 FUN_016562 65 125 72 83 129 ptg000011l:4760119-4765259 Q96AY4 3.7e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4311 FUN_016562 65 125 72 83 129 ptg000011l:4760119-4765259 Q96AY4 1.44e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4312 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 2.62e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4313 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 3.72e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4314 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 1.69e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4315 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 1.33e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4316 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 1.45e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4317 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 2.13e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4318 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 2.13e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4319 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 3.37e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4320 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 4.85e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4321 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 3.16e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4322 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 1.82e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4323 FUN_016568 95 29 31 108 113 ptg000011l:4838488-4844606 Q96AY4 5.01e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4324 FUN_032565 312 42 22 101 26 ptg000023l:33244971-33249656 Q6A198 6.85e-23 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Bos taurus (Bovine) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] GO:0000139; GO:0005789; GO:0006486; GO:0008417; GO:0036065; GO:0036071; GO:0046920 4325 FUN_043665 6 4 23 2 132 NA NA NA NA NA NA NA 4326 FUN_043664 3409 1827 1586 3430 1901 NA NA NA NA NA NA NA 4327 FUN_043667 7 12 10 14 38 NA NA NA NA NA NA NA 4328 FUN_043666 76 245 101 221 603 NA NA NA NA NA NA NA 4329 FUN_043661 738 548 351 192 358 NA NA NA NA NA NA NA 4330 FUN_043660 2215 3107 1258 1304 336 NA NA NA NA NA NA NA 4331 FUN_043663 710 226 250 890 509 NA NA NA NA NA NA NA 4332 FUN_043662 1094 487 572 1085 743 NA NA NA NA NA NA NA 4333 FUN_028681 14 0 1 0 0 NA NA NA NA NA NA NA 4334 FUN_043669 94 294 119 257 702 NA NA NA NA NA NA NA 4335 FUN_043668 3 7 6 3 47 NA NA NA NA NA NA NA 4336 FUN_003928 791 97 508 1959 844 ntLink_8:17067162-17254126 P14381 3.88e-106 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 4337 FUN_042396 46 0 15 0 33 NA NA NA NA NA NA NA 4338 FUN_042394 1 0 2 2 6 NA NA NA NA NA NA NA 4339 FUN_036525 34 0 0 0 52 NA NA NA NA NA NA NA 4340 FUN_042393 0 0 0 0 6 NA NA NA NA NA NA NA 4341 FUN_028173 124 81 87 117 148 ptg000021l:16497713-16498828 A0A1D5NVS8 1.88e-21 NA NA NA NA 4342 FUN_028170 5448 5744 1824 4689 3108 NA NA NA NA NA NA NA 4343 FUN_028175 5317 2943 2095 3535 2100 NA NA NA NA NA NA NA 4344 FUN_028178 0 4 0 261 0 NA NA NA NA NA NA NA 4345 FUN_028179 69 4 4 24 18 ptg000021l:16523906-16528538 A0JPI9 2.32e-51 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 4346 FUN_028179 69 4 4 24 18 ptg000021l:16523906-16528538 A0JPI9 1.47e-48 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 4347 FUN_041284 0 11 36 44 13 NA NA NA NA NA NA NA 4348 FUN_041287 7 19 5 15 24 NA NA NA NA NA NA NA 4349 FUN_041286 0 0 6 0 7 NA NA NA NA NA NA NA 4350 FUN_041281 89 307 93 85 132 NA NA NA NA NA NA NA 4351 FUN_041283 0 0 0 6 0 NA NA NA NA NA NA NA 4352 FUN_041282 8 79 20 38 29 NA NA NA NA NA NA NA 4353 FUN_041288 0 7 0 0 5 NA NA NA NA NA NA NA 4354 FUN_010818 10592 6533 4605 7375 9714 ptg000007l:3124027-3145465 Q6GLY8 7.04e-26 Serine/threonine-protein kinase Sgk1-B (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1-B) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0005783; GO:0006468; GO:0006915; GO:0106310 4355 FUN_010819 0 0 12 0 0 NA NA NA NA NA NA NA 4356 FUN_010816 612 714 220 471 165 NA NA NA NA NA NA NA 4357 FUN_010817 81 178 39 234 95 NA NA NA NA NA NA NA 4358 FUN_010814 1856 1616 1071 1707 1439 NA NA NA NA NA NA NA 4359 FUN_010815 311 252 118 367 384 NA NA NA NA NA NA NA 4360 FUN_010812 1950 1814 1260 1401 1480 NA NA NA NA NA NA NA 4361 FUN_010813 1046 492 299 997 329 ptg000007l:3089914-3092485 Q5F349 9.22e-40 Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196) Gallus gallus (Chicken) carbohydrate phosphorylation [GO:0046835]; protein O-linked glycosylation [GO:0006493]; protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0005789; GO:0006468; GO:0006493; GO:0016773; GO:0019200; GO:0046835 4362 FUN_010810 335 156 233 201 135 ptg000007l:3061955-3069555 Q5GH76 1.78e-39 XK-related protein 4 (hXKR4) [Cleaved into: XK-related protein 4, processed form] Homo sapiens (Human) apoptotic process involved in development [GO:1902742]; engulfment of apoptotic cell [GO:0043652]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005886; GO:0016020; GO:0017128; GO:0043652; GO:0070782; GO:1902742 4363 FUN_010811 273 124 165 194 139 NA NA NA NA NA NA NA 4364 FUN_041136 14 0 0 0 19 NA NA NA NA NA NA NA 4365 FUN_041135 0 0 0 0 55 NA NA NA NA NA NA NA 4366 FUN_041134 0 0 14 0 0 NA NA NA NA NA NA NA 4367 FUN_041133 0 0 9 3 0 NA NA NA NA NA NA NA 4368 FUN_041132 16 35 23 14 107 NA NA NA NA NA NA NA 4369 FUN_009014 1488 815 787 1100 730 ptg000004l:1443297-1458909 Q6PA97 3.3e-21 Trafficking protein particle complex subunit 9 (NIK- and IKBKB-binding protein homolog) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154] GO:0005783; GO:0005794; GO:0030154 4370 FUN_009015 0 0 0 12 0 NA NA NA NA NA NA NA 4371 FUN_009016 230 254 328 578 299 NA NA NA NA NA NA NA 4372 FUN_009017 659 795 391 387 595 NA NA NA NA NA NA NA 4373 FUN_009010 3300 2585 1316 1992 1414 NA NA NA NA NA NA NA 4374 FUN_009011 176 2393 69 2196 2253 NA NA NA NA NA NA NA 4375 FUN_009012 155784 145658 36227 116070 83309 NA NA NA NA NA NA NA 4376 FUN_009013 75 197 114 104 32 ptg000004l:1440491-1441502 P18870 1.99e-34 Transcription factor Jun (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) Gallus gallus (Chicken) positive regulation by host of viral transcription [GO:0043923]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of cell population proliferation [GO:0042127]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0030307; GO:0042127; GO:0043923; GO:0045944; GO:0051726 4377 FUN_009019 174 222 201 434 115 NA NA NA NA NA NA NA 4378 FUN_000646 0 0 0 23 0 NA NA NA NA NA NA NA 4379 FUN_029242 298 260 219 368 285 NA NA NA NA NA NA NA 4380 FUN_000644 106 38 36 43 16 ntLink_6:5324142-5325878 Q9VUL9 3.07e-52 Glycoprotein 3-alpha-L-fucosyltransferase A (EC 2.4.1.214) (Core alpha-(1,3)-fucosyltransferase) Drosophila melanogaster (Fruit fly) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; protein glycosylation [GO:0006486] GO:0005797; GO:0006486; GO:0007399; GO:0008417; GO:0018392; GO:0032580; GO:0036065; GO:0036071; GO:0046920 4381 FUN_003633 0 0 0 0 6 NA NA NA NA NA NA NA 4382 FUN_029245 58 27 53 47 28 NA NA NA NA NA NA NA 4383 FUN_000641 720 1189 674 2236 2331 ntLink_6:5281162-5286911 Q12986 0 Transcriptional repressor NF-X1 (EC 2.3.2.-) (Nuclear transcription factor, X box-binding protein 1) Homo sapiens (Human) inflammatory response [GO:0006954]; negative regulation of MHC class II biosynthetic process [GO:0045347]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of DNA-templated transcription [GO:0006355]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000785; GO:0000977; GO:0000981; GO:0001227; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0005886; GO:0006355; GO:0006366; GO:0006954; GO:0008270; GO:0016567; GO:0045347; GO:0051865; GO:0061630 4384 FUN_032907 2555 1784 796 1054 756 NA NA NA NA NA NA NA 4385 FUN_010108 63 88 0 0 31 NA NA NA NA NA NA NA 4386 FUN_040669 428 261 223 415 228 NA NA NA NA NA NA NA 4387 FUN_040665 125 160 39 342 167 NA NA NA NA NA NA NA 4388 FUN_040666 21 20 30 18 27 NA NA NA NA NA NA NA 4389 FUN_040667 403 313 321 193 412 NA NA NA NA NA NA NA 4390 FUN_010102 0 0 13 0 0 NA NA NA NA NA NA NA 4391 FUN_009907 0 0 0 7 71 NA NA NA NA NA NA NA 4392 FUN_024408 1076 735 729 1408 1840 NA NA NA NA NA NA NA 4393 FUN_008058 113 102 74 115 129 NA NA NA NA NA NA NA 4394 FUN_024407 63 0 15 193 52 NA NA NA NA NA NA NA 4395 FUN_024404 0 0 0 8 4 NA NA NA NA NA NA NA 4396 FUN_024402 1657 869 813 945 413 ptg000018l:5856780-5861518 O54865 1.62e-53 Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit) Mus musculus (Mouse) cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to oxygen levels [GO:0070482]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555] GO:0004016; GO:0004383; GO:0005525; GO:0005737; GO:0006182; GO:0008074; GO:0019934; GO:0020037; GO:0032991; GO:0038060; GO:0043167; GO:0044877; GO:0046872; GO:0047805; GO:0048786; GO:0051879; GO:0070482; GO:0071732; GO:0098831; GO:0098978; GO:0099555 4397 FUN_024402 1657 869 813 945 413 ptg000018l:5856780-5861518 O54865 7.12e-33 Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit) Mus musculus (Mouse) cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to oxygen levels [GO:0070482]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555] GO:0004016; GO:0004383; GO:0005525; GO:0005737; GO:0006182; GO:0008074; GO:0019934; GO:0020037; GO:0032991; GO:0038060; GO:0043167; GO:0044877; GO:0046872; GO:0047805; GO:0048786; GO:0051879; GO:0070482; GO:0071732; GO:0098831; GO:0098978; GO:0099555 4398 FUN_008052 580 535 293 633 393 NA NA NA NA NA NA NA 4399 FUN_024400 0 0 5 14 12 NA NA NA NA NA NA NA 4400 FUN_024401 746 379 273 531 853 ptg000018l:5843334-5851333 P20595 1e-99 Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit) Rattus norvegicus (Rat) cellular response to nitric oxide [GO:0071732]; cGMP biosynthetic process [GO:0006182]; cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to oxygen levels [GO:0070482]; trans-synaptic signaling by nitric oxide, modulating synaptic transmission [GO:0099555] GO:0004383; GO:0005525; GO:0005829; GO:0006182; GO:0008074; GO:0019934; GO:0020037; GO:0032991; GO:0038060; GO:0043167; GO:0044877; GO:0046872; GO:0048786; GO:0051879; GO:0070482; GO:0071732; GO:0098831; GO:0098978; GO:0099555 4401 FUN_038728 0 0 0 9 0 NA NA NA NA NA NA NA 4402 FUN_038726 160 16 87 100 55 NA NA NA NA NA NA NA 4403 FUN_038727 402 297 248 433 440 ptg000027l:10634998-10661226 P30566 6.08e-25 Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; aerobic respiration [GO:0009060]; AMP biosynthetic process [GO:0006167]; AMP salvage [GO:0044209]; GMP biosynthetic process [GO:0006177]; purine nucleotide biosynthetic process [GO:0006164]; response to hypoxia [GO:0001666]; response to muscle activity [GO:0014850]; response to nutrient [GO:0007584]; response to starvation [GO:0042594] GO:0001666; GO:0004018; GO:0005829; GO:0006164; GO:0006167; GO:0006177; GO:0006189; GO:0007584; GO:0009060; GO:0014850; GO:0032991; GO:0042594; GO:0042802; GO:0044208; GO:0044209; GO:0070626; GO:0097294 4404 FUN_038724 21 0 0 6 19 NA NA NA NA NA NA NA 4405 FUN_038722 3 0 5 162 30 NA NA NA NA NA NA NA 4406 FUN_038723 44 0 11 4 104 NA NA NA NA NA NA NA 4407 FUN_038720 15 0 43 93 27 NA NA NA NA NA NA NA 4408 FUN_038721 90 66 64 45 71 NA NA NA NA NA NA NA 4409 FUN_028958 26 2 5 0 0 NA NA NA NA NA NA NA 4410 FUN_015055 984 833 410 753 834 NA NA NA NA NA NA NA 4411 FUN_028955 1053 197 755 976 1447 ptg000022l:6362154-6386862 O02751 1.43e-24 Craniofacial development protein 2 (p97 bucentaur protein) Bos taurus (Bovine) chromatin remodeling [GO:0006338] GO:0003824; GO:0005634; GO:0005737; GO:0006338 4412 FUN_015057 3694 3469 1559 2651 1314 ptg000009l:5697967-5701729 Q5RC74 1.36e-24 Derlin-2 (Der1-like protein 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endoplasmic reticulum unfolded protein response [GO:0030968]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; retrograde protein transport, ER to cytosol [GO:0030970]; suckling behavior [GO:0001967]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001967; GO:0005047; GO:0005769; GO:0005770; GO:0005789; GO:0008284; GO:0030307; GO:0030433; GO:0030968; GO:0030970; GO:1904153 4413 FUN_028950 87 99 122 98 124 ptg000022l:6297600-6300453 Q9NSA2 1.4e-32 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 4414 FUN_028951 250 0 41 57 75 NA NA NA NA NA NA NA 4415 FUN_015053 3644 2413 1359 1921 1211 NA NA NA NA NA NA NA 4416 FUN_028953 524 431 167 281 195 ptg000022l:6336568-6338684 P17971 3.96e-71 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 4417 FUN_028303 4019 2851 1815 4263 2480 NA NA NA NA NA NA NA 4418 FUN_028302 643 385 250 776 638 NA NA NA NA NA NA NA 4419 FUN_015317 8075 3684 3927 6897 5057 NA NA NA NA NA NA NA 4420 FUN_041186 16 14 0 0 6 NA NA NA NA NA NA NA 4421 FUN_014908 1615 1733 773 1071 1122 ptg000009l:4153588-4156672 Q9Y818 1.2e-24 Ubiquitin-conjugating enzyme E2 15 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 15) (Ubiquitin carrier protein 15) (Ubiquitin-protein ligase 15) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005524; GO:0005634; GO:0006511; GO:0043161; GO:0061631 4422 FUN_014909 1341 477 751 1190 1476 NA NA NA NA NA NA NA 4423 FUN_014900 452 492 348 604 629 ptg000009l:4101174-4106018 Q9WVS8 4.94e-108 Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5) Mus musculus (Mouse) calcineurin-NFAT signaling cascade [GO:0033173]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cellular response to growth factor stimulus [GO:0071363]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to laminar fluid shear stress [GO:0071499]; cellular response to transforming growth factor beta stimulus [GO:0071560]; ERK5 cascade [GO:0070375]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of heterotypic cell-cell adhesion [GO:0034115]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of response to cytokine stimulus [GO:0060761]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter in response to stress [GO:0036003]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of angiogenesis [GO:0045765] GO:0000165; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0007049; GO:0016605; GO:0018105; GO:0030154; GO:0033173; GO:0034115; GO:0035556; GO:0036003; GO:0043066; GO:0045765; GO:0045944; GO:0046777; GO:0051019; GO:0051247; GO:0060761; GO:0070301; GO:0070375; GO:0070885; GO:0071363; GO:0071499; GO:0071560; GO:0106310; GO:1902176; GO:2000352; GO:2001240 4424 FUN_014902 1335 2215 1056 971 870 NA NA NA NA NA NA NA 4425 FUN_014903 527 474 177 589 432 NA NA NA NA NA NA NA 4426 FUN_014904 100 79 14 124 41 ptg000009l:4116396-4118184 Q8BTJ4 1.13e-87 Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) Mus musculus (Mouse) blood coagulation [GO:0007596]; positive regulation of blood coagulation [GO:0030194]; purine ribonucleoside catabolic process [GO:0046130] GO:0005886; GO:0007596; GO:0030194; GO:0046130; GO:0046872; GO:0047710 4427 FUN_014905 800 474 493 604 694 NA NA NA NA NA NA NA 4428 FUN_014906 296 205 241 275 170 NA NA NA NA NA NA NA 4429 FUN_014907 701 327 128 611 607 NA NA NA NA NA NA NA 4430 FUN_039099 0 0 0 10 0 NA NA NA NA NA NA NA 4431 FUN_039097 0 0 0 0 10 NA NA NA NA NA NA NA 4432 FUN_039092 118 151 91 122 158 NA NA NA NA NA NA NA 4433 FUN_039091 3640 2775 1847 4014 2998 ptg000027l:14506084-14568738 P21328 1.57e-27 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 4434 FUN_020895 18 0 0 10 39 ptg000015l:9644773-9651859 P04323 1.48e-74 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 4435 FUN_020894 17 0 0 0 52 ptg000015l:9635285-9640715 Q03278 1.18e-53 Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nasonia vitripennis (Parasitic wasp) NA GO:0003964; GO:0004519; GO:0046872 4436 FUN_020894 17 0 0 0 52 ptg000015l:9635285-9640715 Q03278 1.18e-53 Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nasonia vitripennis (Parasitic wasp) NA GO:0003964; GO:0004519; GO:0046872 4437 FUN_020894 17 0 0 0 52 ptg000015l:9635285-9640715 Q03278 1.05e-30 Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nasonia vitripennis (Parasitic wasp) NA GO:0003964; GO:0004519; GO:0046872 4438 FUN_020897 8 4 0 0 2 NA NA NA NA NA NA NA 4439 FUN_020896 4 0 10 9 47 NA NA NA NA NA NA NA 4440 FUN_020891 4 0 1 0 10 NA NA NA NA NA NA NA 4441 FUN_020892 0 13 11 0 37 NA NA NA NA NA NA NA 4442 FUN_020899 0 0 0 0 11 NA NA NA NA NA NA NA 4443 FUN_022945 951 469 519 1016 544 ptg000017l:1857772-1858471 E7FDB3 1.41e-23 Nanos homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of translation [GO:0017148]; oogenesis [GO:0048477] GO:0003729; GO:0005737; GO:0008270; GO:0017148; GO:0030371; GO:0048471; GO:0048477; GO:0060293 4444 FUN_022944 204 92 165 151 171 NA NA NA NA NA NA NA 4445 FUN_022947 37 33 12 24 43 NA NA NA NA NA NA NA 4446 FUN_022946 2800 1972 1328 2208 2037 NA NA NA NA NA NA NA 4447 FUN_022941 1196 1075 529 1095 2144 NA NA NA NA NA NA NA 4448 FUN_022940 1846 1480 739 1023 1118 ptg000017l:1774268-1781423 Q8QZV4 1.41e-46 Serine/threonine-protein kinase 32C (EC 2.7.11.1) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0005524; GO:0018105; GO:0035556; GO:0046872; GO:0106310 4449 FUN_022940 1846 1480 739 1023 1118 ptg000017l:1774268-1781423 Q8QZV4 1.41e-46 Serine/threonine-protein kinase 32C (EC 2.7.11.1) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0005524; GO:0018105; GO:0035556; GO:0046872; GO:0106310 4450 FUN_022949 1247 843 527 830 753 NA NA NA NA NA NA NA 4451 FUN_022948 103 186 33 70 137 ptg000017l:1882684-1884133 O16374 3.2e-28 Beta-1,4-galactosyltransferase galt-1 (EC 2.4.1.-) Caenorhabditis elegans N-glycan processing [GO:0006491]; protein galactosylation [GO:0042125] GO:0003831; GO:0006491; GO:0032580; GO:0035250; GO:0042125; GO:0043229; GO:0046872 4452 FUN_038590 32 2 22 8 0 NA NA NA NA NA NA NA 4453 FUN_038594 0 0 0 0 6 NA NA NA NA NA NA NA 4454 FUN_038596 0 0 0 0 17 NA NA NA NA NA NA NA 4455 FUN_003627 0 0 18 22 17 ntLink_8:13707833-13711563 P57756 1.98e-41 Ficolin-2 (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin-beta) (L-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; protein localization to cell surface [GO:0034394]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001664; GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0033691; GO:0034394; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0062023; GO:0097367; GO:1903028; GO:1905370 4456 FUN_018030 7034 6707 5539 8312 3612 ptg000012l:3584668-3585280 P59055 3.76e-34 Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2) Mus musculus (Mouse) apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0006915; GO:0043065; GO:0043565; GO:0045944 4457 FUN_018031 301 199 230 508 376 NA NA NA NA NA NA NA 4458 FUN_018032 313 53 397 686 560 NA NA NA NA NA NA NA 4459 FUN_027818 0 0 0 20 0 NA NA NA NA NA NA NA 4460 FUN_018035 281 126 140 231 186 NA NA NA NA NA NA NA 4461 FUN_018036 997 337 309 319 636 NA NA NA NA NA NA NA 4462 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 7.11e-34 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4463 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 8.08e-32 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4464 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 9.66e-31 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4465 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 4.51e-30 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4466 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 1.29e-29 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4467 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 1.55e-29 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4468 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 1.19e-28 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4469 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 8.89e-28 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4470 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 1.01e-27 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4471 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 6.38e-23 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4472 FUN_018037 1689 793 4 0 1888 ptg000012l:3697552-3699106 Q01456 1.07e-22 Ovarian abundant message protein (Protein OAM) Ascaris suum (Pig roundworm) (Ascaris lumbricoides) NA NA 4473 FUN_018038 262 0 28 216 129 NA NA NA NA NA NA NA 4474 FUN_018039 321 0 0 0 405 NA NA NA NA NA NA NA 4475 FUN_027816 203 0 0 24 0 NA NA NA NA NA NA NA 4476 FUN_027817 873 87 45 53 9 NA NA NA NA NA NA NA 4477 FUN_027810 12 107 61 602 5 NA NA NA NA NA NA NA 4478 FUN_027811 174 139 106 185 138 NA NA NA NA NA NA NA 4479 FUN_027812 12 3 0 3 0 NA NA NA NA NA NA NA 4480 FUN_027813 7134 12482 4081 7161 3829 NA NA NA NA NA NA NA 4481 FUN_040077 933 669 366 699 728 ptg000031l:3911854-3914602 Q5RCK5 3.18e-95 Ankyrin repeat and SOCS box protein 7 (ASB-7) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] GO:0016567; GO:0035556 4482 FUN_040076 607 271 207 359 456 ptg000031l:3895457-3911555 Q9NBX4 2.54e-27 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 4483 FUN_040079 34 20 4 16 18 NA NA NA NA NA NA NA 4484 FUN_023311 96 17 81 64 180 NA NA NA NA NA NA NA 4485 FUN_023310 1050 677 293 854 647 NA NA NA NA NA NA NA 4486 FUN_023317 56 27 0 11 53 NA NA NA NA NA NA NA 4487 FUN_023316 647 342 144 312 200 NA NA NA NA NA NA NA 4488 FUN_023319 88 51 30 44 33 NA NA NA NA NA NA NA 4489 FUN_023318 177 71 120 179 210 NA NA NA NA NA NA NA 4490 FUN_025416 32 8 38 16 2 ptg000019l:2374868-2375423 Q8K2J9 5.65e-29 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 4491 FUN_025417 0 16 0 0 9 ptg000019l:2379886-2381189 Q8K2J9 2.32e-62 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 4492 FUN_025412 2029 1910 962 2399 2035 NA NA NA NA NA NA NA 4493 FUN_025410 5258 2144 1147 1480 1031 NA NA NA NA NA NA NA 4494 FUN_025411 337 99 128 227 105 ptg000019l:2347815-2350444 P97292 1.46e-31 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 4495 FUN_043601 1251 1488 1213 2490 3483 NA NA NA NA NA NA NA 4496 FUN_025418 209 283 0 191 0 ptg000019l:2385460-2386879 Q96KE9 2.19e-63 BTB/POZ domain-containing protein 6 (Lens BTB domain protein) Homo sapiens (Human) neurogenesis [GO:0022008] GO:0005829; GO:0022008 4497 FUN_025419 333 211 0 2 0 ptg000019l:2392861-2393800 Q9BX70 5.31e-71 BTB/POZ domain-containing protein 2 Homo sapiens (Human) neurogenesis [GO:0022008] GO:0000932; GO:0005829; GO:0022008 4498 FUN_043600 1212 388 347 797 505 NA NA NA NA NA NA NA 4499 FUN_043607 0 0 26 9 6 NA NA NA NA NA NA NA 4500 FUN_010871 0 0 0 0 27 NA NA NA NA NA NA NA 4501 FUN_008066 178 71 170 163 103 ptg000002l:7628115-7633871 Q75WE7 4.18e-78 von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog) (Mast cell surface antigen 1) (Masa-1) Rattus norvegicus (Rat) NA NA 4502 FUN_043605 1514 1361 897 1589 1182 NA NA NA NA NA NA NA 4503 FUN_043604 27440 36165 16172 23583 11700 NA NA NA NA NA NA NA 4504 FUN_037579 0 0 4 0 9 NA NA NA NA NA NA NA 4505 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 1.18e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4506 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 2.11e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4507 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 8.93e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4508 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 1.36e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4509 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 1.63e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4510 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 1.27e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4511 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 2.59e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4512 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 8.58e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4513 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 1.28e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4514 FUN_018694 879 72 305 125 78 ptg000012l:12054174-12057304 Q96AY4 1.93e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4515 FUN_018691 45 9 26 0 19 NA NA NA NA NA NA NA 4516 FUN_018692 167 21 74 38 89 NA NA NA NA NA NA NA 4517 FUN_018693 14 0 0 10 0 NA NA NA NA NA NA NA 4518 FUN_019341 912 800 310 704 536 NA NA NA NA NA NA NA 4519 FUN_019340 107 5 15 2 29 NA NA NA NA NA NA NA 4520 FUN_019343 731 204 305 384 251 ptg000015l:1305827-1307462 P82251 2.26e-80 b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Homo sapiens (Human) L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804]; protein-containing complex assembly [GO:0065003] GO:0005886; GO:0015175; GO:0015179; GO:0015184; GO:0015804; GO:0015811; GO:0016324; GO:0031526; GO:0042605; GO:0065003 4521 FUN_019342 533 1301 166 778 522 NA NA NA NA NA NA NA 4522 FUN_019347 471 494 275 614 433 NA NA NA NA NA NA NA 4523 FUN_019346 7996 4754 3409 7708 6287 ptg000015l:1322092-1341111 Q3UH66 5.17e-31 Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase lysine-deficient 2) (Protein kinase with no lysine 2) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; ion homeostasis [GO:0050801]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sodium ion transport [GO:0010766]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of potassium ion import across plasma membrane [GO:1903288]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0008285; GO:0010766; GO:0019869; GO:0019870; GO:0035556; GO:0046777; GO:0050801; GO:0070373; GO:0090263; GO:0106310; GO:1903288; GO:2000651 4524 FUN_019346 7996 4754 3409 7708 6287 ptg000015l:1322092-1341111 Q3UH66 9.31e-26 Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase lysine-deficient 2) (Protein kinase with no lysine 2) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; ion homeostasis [GO:0050801]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of sodium ion transport [GO:0010766]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of potassium ion import across plasma membrane [GO:1903288]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0008285; GO:0010766; GO:0019869; GO:0019870; GO:0035556; GO:0046777; GO:0050801; GO:0070373; GO:0090263; GO:0106310; GO:1903288; GO:2000651 4525 FUN_019349 119 29 28 22 133 NA NA NA NA NA NA NA 4526 FUN_019348 0 0 0 11 0 NA NA NA NA NA NA NA 4527 FUN_033820 900 424 407 843 682 NA NA NA NA NA NA NA 4528 FUN_033822 2131 1268 1288 1456 1453 NA NA NA NA NA NA NA 4529 FUN_033823 2756 1650 2392 3331 3652 NA NA NA NA NA NA NA 4530 FUN_033824 3222 2574 1456 3888 3686 NA NA NA NA NA NA NA 4531 FUN_039849 112 262 82 211 175 ptg000031l:866522-872245 Q494W8 2.03e-43 CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0022848; GO:0030594; GO:0034220; GO:0042166; GO:0042391; GO:0043005; GO:0045202; GO:0050877; GO:0098794; GO:1904315 4532 FUN_033826 280 165 94 308 13 ptg000024l:1707820-1712341 Q6L9W6 1.49e-21 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 4533 FUN_033827 47 55 16 125 2 NA NA NA NA NA NA NA 4534 FUN_039845 10 9 5 41 60 NA NA NA NA NA NA NA 4535 FUN_039846 1 0 0 0 13 NA NA NA NA NA NA NA 4536 FUN_039847 30 39 0 93 6 ptg000031l:848393-849610 P14381 1.56e-77 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 4537 FUN_039840 52 29 85 60 31 NA NA NA NA NA NA NA 4538 FUN_039841 140 146 101 197 70 NA NA NA NA NA NA NA 4539 FUN_039842 0 61 0 0 0 NA NA NA NA NA NA NA 4540 FUN_039843 153 137 151 88 2426 NA NA NA NA NA NA NA 4541 FUN_018966 0 0 13 0 28 NA NA NA NA NA NA NA 4542 FUN_007089 12 0 0 9 0 NA NA NA NA NA NA NA 4543 FUN_007088 0 0 0 6 70 NA NA NA NA NA NA NA 4544 FUN_018960 0 0 16 0 69 NA NA NA NA NA NA NA 4545 FUN_018961 0 0 14 0 0 NA NA NA NA NA NA NA 4546 FUN_007085 2436 1781 1382 1473 2380 NA NA NA NA NA NA NA 4547 FUN_007084 1044 775 759 1324 992 NA NA NA NA NA NA NA 4548 FUN_007087 0 35 37 0 53 NA NA NA NA NA NA NA 4549 FUN_007086 139 316 191 134 99 NA NA NA NA NA NA NA 4550 FUN_007081 13 0 0 13 0 NA NA NA NA NA NA NA 4551 FUN_007080 837 587 302 354 311 ptg000001l:20218633-20265845 Q0EEE2 5.37e-31 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 4552 FUN_007080 837 587 302 354 311 ptg000001l:20218633-20265845 Q0EEE2 1.42e-30 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 4553 FUN_018969 551 206 304 384 1239 NA NA NA NA NA NA NA 4554 FUN_005811 2465 2077 2062 3031 2553 ptg000001l:4186225-4198454 Q923J6 2.84e-28 Dynein axonemal heavy chain 12 (Bm259) Rattus norvegicus (Rat) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 4555 FUN_005811 2465 2077 2062 3031 2553 ptg000001l:4186225-4198454 Q923J6 2.84e-28 Dynein axonemal heavy chain 12 (Bm259) Rattus norvegicus (Rat) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 4556 FUN_005811 2465 2077 2062 3031 2553 ptg000001l:4186225-4198454 Q923J6 2.84e-28 Dynein axonemal heavy chain 12 (Bm259) Rattus norvegicus (Rat) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 4557 FUN_005812 1656 950 1015 1439 1212 ptg000001l:4203859-4215020 Q63170 1.11e-24 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 4558 FUN_005812 1656 950 1015 1439 1212 ptg000001l:4203859-4215020 Q63170 4.13e-22 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 4559 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 1.66e-76 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4560 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 1.66e-76 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4561 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 1.66e-76 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4562 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 5.8e-38 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4563 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 5.8e-38 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4564 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 5.49e-32 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4565 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 9.22e-26 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4566 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 9.22e-26 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4567 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 1.93e-25 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4568 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 1.93e-25 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4569 FUN_005813 1561 1070 946 1075 1172 ptg000001l:4215506-4253674 Q6ZR08 2.98e-25 Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005858; GO:0005874; GO:0007018; GO:0008569; GO:0045505; GO:0051959 4570 FUN_005814 3750 2339 1809 2786 2067 NA NA NA NA NA NA NA 4571 FUN_005815 2586 2798 1273 2959 1890 ptg000001l:4321297-4326970 Q3ZCL5 5.56e-68 Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) Bos taurus (Bovine) intracellular protein transport [GO:0006886]; mitophagy [GO:0000423]; protein localization to phagophore assembly site [GO:0034497]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0000423; GO:0005543; GO:0006886; GO:0019904; GO:0032588; GO:0034315; GO:0034497 4572 FUN_005818 4 0 21 0 87 NA NA NA NA NA NA NA 4573 FUN_005819 26 10 17 0 146 NA NA NA NA NA NA NA 4574 FUN_028198 338 276 294 338 305 ptg000021l:16798133-16803663 Q68FV3 1.15e-66 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Rattus norvegicus (Rat) fucosylation [GO:0036065]; N-glycan fucosylation [GO:0036071]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008417; GO:0032580; GO:0036065; GO:0036071; GO:0046920 4575 FUN_016095 41 18 7 7 19 NA NA NA NA NA NA NA 4576 FUN_007920 4197 2492 2373 5646 3832 ptg000002l:6203427-6234850 Q96L93 4.77e-37 Kinesin-like protein KIF16B (Sorting nexin-23) Homo sapiens (Human) early endosome to late endosome transport [GO:0045022]; endoderm development [GO:0007492]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; formation of primary germ layer [GO:0001704]; Golgi to endosome transport [GO:0006895]; microtubule-based movement [GO:0007018]; receptor catabolic process [GO:0032801]; regulation of receptor recycling [GO:0001919] GO:0001704; GO:0001919; GO:0003777; GO:0005524; GO:0005547; GO:0005737; GO:0005768; GO:0005769; GO:0005819; GO:0005829; GO:0005871; GO:0005874; GO:0006895; GO:0007018; GO:0007173; GO:0007492; GO:0008017; GO:0008543; GO:0008574; GO:0016887; GO:0031901; GO:0032266; GO:0032801; GO:0043325; GO:0045022; GO:0080025 4577 FUN_033954 1136 289 0 0 107 NA NA NA NA NA NA NA 4578 FUN_042980 670 155 18 537 729 NA NA NA NA NA NA NA 4579 FUN_004261 12408 9298 5983 11001 6075 NA NA NA NA NA NA NA 4580 FUN_028194 693 488 451 322 349 NA NA NA NA NA NA NA 4581 FUN_004262 95 0 14 0 14 NA NA NA NA NA NA NA 4582 FUN_035286 24 25 20 38 73 NA NA NA NA NA NA NA 4583 FUN_035287 0 0 0 0 21 NA NA NA NA NA NA NA 4584 FUN_035284 46 101 393 222 62 NA NA NA NA NA NA NA 4585 FUN_035285 2492 1758 1002 1307 886 NA NA NA NA NA NA NA 4586 FUN_035282 231 17 298 278 33 ptg000025l:6036886-6037588 A0A3M6TIF0 9.7e-62 NA NA NA NA 4587 FUN_035283 148 0 268 387 32 ptg000025l:6037644-6038010 A0A3M6TIF0 1.44e-54 NA NA NA NA 4588 FUN_035280 167 215 116 113 244 NA NA NA NA NA NA NA 4589 FUN_035281 2539 1821 847 2144 1525 NA NA NA NA NA NA NA 4590 FUN_033950 583 317 269 388 298 NA NA NA NA NA NA NA 4591 FUN_035288 110 50 74 31 53 NA NA NA NA NA NA NA 4592 FUN_033951 368 588 684 1324 937 NA NA NA NA NA NA NA 4593 FUN_036959 0 8 0 0 0 NA NA NA NA NA NA NA 4594 FUN_036958 70 67 0 61 52 ptg000026l:3887291-3894109 Q68F72 6.78e-37 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 4595 FUN_033952 4614 3805 3429 5162 3793 NA NA NA NA NA NA NA 4596 FUN_036953 307 349 120 320 96 ptg000026l:3799772-3814506 Q68F72 2.44e-36 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 4597 FUN_036953 307 349 120 320 96 ptg000026l:3799772-3814506 Q68F72 8.91e-22 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 4598 FUN_010687 22 60 0 15 2 NA NA NA NA NA NA NA 4599 FUN_036951 371 195 65 380 10 NA NA NA NA NA NA NA 4600 FUN_036950 17 0 27 55 0 NA NA NA NA NA NA NA 4601 FUN_036957 287 126 263 175 537 ptg000026l:3875128-3879332 Q68F72 3.03e-36 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 4602 FUN_036956 1668 1589 764 1686 831 ptg000026l:3850418-3870523 Q96DM1 9.24e-75 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 4603 FUN_036955 2578 2039 1031 2228 1756 NA NA NA NA NA NA NA 4604 FUN_010686 112 44 66 224 53 NA NA NA NA NA NA NA 4605 FUN_034889 826 375 303 456 349 ptg000025l:1225661-1227737 Q8MKL1 8.62e-34 UPF0598 protein CG30010 Drosophila melanogaster (Fruit fly) wound healing [GO:0042060] GO:0042060 4606 FUN_034888 1301 1002 657 1107 1174 NA NA NA NA NA NA NA 4607 FUN_028336 215 0 0 307 14 NA NA NA NA NA NA NA 4608 FUN_034883 872 648 579 1024 853 NA NA NA NA NA NA NA 4609 FUN_034882 740 36 69 385 187 NA NA NA NA NA NA NA 4610 FUN_034881 555 1344 732 1062 668 NA NA NA NA NA NA NA 4611 FUN_034887 529 640 309 486 586 NA NA NA NA NA NA NA 4612 FUN_034886 95 81 56 48 110 NA NA NA NA NA NA NA 4613 FUN_034884 85918 54872 31592 67184 42225 NA NA NA NA NA NA NA 4614 FUN_035758 785 153 777 1048 612 ptg000025l:11391711-11393160 Q9PVY8 9.66e-60 Forkhead box protein C2-B (FoxC2-B) (FoxC2b) (Fork head domain-related protein 4') (FD-4') (xFD-4') (xFD4 B) Xenopus laevis (African clawed frog) mesoderm development [GO:0007498]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0007498; GO:0043565; GO:0045893; GO:0045944; GO:1990841 4615 FUN_035759 0 1 6 6 5 NA NA NA NA NA NA NA 4616 FUN_035751 10024 7454 6393 8146 5212 ptg000025l:11309564-11317392 P54802 8.06e-38 Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Homo sapiens (Human) cerebellar Purkinje cell layer development [GO:0021680]; heparan sulfate proteoglycan catabolic process [GO:0030200]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] GO:0004561; GO:0005764; GO:0007040; GO:0007399; GO:0021680; GO:0030200; GO:0042474; GO:0043202; GO:0045475; GO:0046548; GO:0060119; GO:0070062 4617 FUN_035751 10024 7454 6393 8146 5212 ptg000025l:11309564-11317392 P54802 1.63e-28 Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Homo sapiens (Human) cerebellar Purkinje cell layer development [GO:0021680]; heparan sulfate proteoglycan catabolic process [GO:0030200]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] GO:0004561; GO:0005764; GO:0007040; GO:0007399; GO:0021680; GO:0030200; GO:0042474; GO:0043202; GO:0045475; GO:0046548; GO:0060119; GO:0070062 4618 FUN_035751 10024 7454 6393 8146 5212 ptg000025l:11309564-11317392 P54802 1.23e-26 Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Homo sapiens (Human) cerebellar Purkinje cell layer development [GO:0021680]; heparan sulfate proteoglycan catabolic process [GO:0030200]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] GO:0004561; GO:0005764; GO:0007040; GO:0007399; GO:0021680; GO:0030200; GO:0042474; GO:0043202; GO:0045475; GO:0046548; GO:0060119; GO:0070062 4619 FUN_035751 10024 7454 6393 8146 5212 ptg000025l:11309564-11317392 P54802 2.4e-24 Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Homo sapiens (Human) cerebellar Purkinje cell layer development [GO:0021680]; heparan sulfate proteoglycan catabolic process [GO:0030200]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] GO:0004561; GO:0005764; GO:0007040; GO:0007399; GO:0021680; GO:0030200; GO:0042474; GO:0043202; GO:0045475; GO:0046548; GO:0060119; GO:0070062 4620 FUN_035751 10024 7454 6393 8146 5212 ptg000025l:11309564-11317392 P54802 2.75e-21 Alpha-N-acetylglucosaminidase (EC 3.2.1.50) (N-acetyl-alpha-glucosaminidase) (NAG) [Cleaved into: Alpha-N-acetylglucosaminidase 82 kDa form; Alpha-N-acetylglucosaminidase 77 kDa form] Homo sapiens (Human) cerebellar Purkinje cell layer development [GO:0021680]; heparan sulfate proteoglycan catabolic process [GO:0030200]; inner ear receptor cell development [GO:0060119]; locomotor rhythm [GO:0045475]; lysosome organization [GO:0007040]; middle ear morphogenesis [GO:0042474]; nervous system development [GO:0007399]; retinal rod cell development [GO:0046548] GO:0004561; GO:0005764; GO:0007040; GO:0007399; GO:0021680; GO:0030200; GO:0042474; GO:0043202; GO:0045475; GO:0046548; GO:0060119; GO:0070062 4621 FUN_035752 3555 2109 1593 2517 2088 ptg000025l:11320585-11337482 P28749 2.09e-32 Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1) Homo sapiens (Human) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; negative regulation of cellular senescence [GO:2000773]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of lipid kinase activity [GO:0043550] GO:0000122; GO:0000785; GO:0000977; GO:0005654; GO:0005667; GO:0006325; GO:0007049; GO:0010629; GO:0030154; GO:0043550; GO:1990841; GO:2000134; GO:2000773 4622 FUN_035753 237 157 150 146 161 NA NA NA NA NA NA NA 4623 FUN_035754 418 219 249 246 313 ptg000025l:11341380-11344636 Q5NDE7 1.69e-164 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGnT2) (EC 2.4.1.312) (Extracellular O-linked N-acetylglucosamine transferase-like) (Glycosyltransferase-like domain-containing protein 2) Xenopus laevis (African clawed frog) neuron migration [GO:0001764]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] GO:0001764; GO:0005783; GO:0005789; GO:0006493; GO:0008375; GO:0035269 4624 FUN_031459 510 89 537 499 1859 NA NA NA NA NA NA NA 4625 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 7.77e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4626 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 1.18e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4627 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 4.1e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4628 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 1.6e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4629 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 4.22e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4630 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 7.02e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4631 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 5.91e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4632 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 1.15e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4633 FUN_031457 96 12 93 1 258 ptg000023l:21672214-21680267 Q7RTR2 7.21e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4634 FUN_031455 0 0 34 0 22 NA NA NA NA NA NA NA 4635 FUN_031454 12 0 0 21 0 NA NA NA NA NA NA NA 4636 FUN_031452 2 10 9 119 0 NA NA NA NA NA NA NA 4637 FUN_000307 259 67 24 195 17 NA NA NA NA NA NA NA 4638 FUN_001663 4317 913 669 2530 2069 NA NA NA NA NA NA NA 4639 FUN_001661 0 12 21 21 0 NA NA NA NA NA NA NA 4640 FUN_001660 11 39 26 8 31 NA NA NA NA NA NA NA 4641 FUN_001667 0 3 0 15 0 NA NA NA NA NA NA NA 4642 FUN_001666 0 18 0 77 0 ntLink_6:14844323-14849053 C3ZQF9 2.87e-27 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 4643 FUN_001665 548 280 437 1707 977 ntLink_6:14819135-14820215 C3ZQF9 2.18e-29 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 4644 FUN_001664 1194 1474 571 1570 1023 NA NA NA NA NA NA NA 4645 FUN_001668 18454 14341 11084 22690 7199 NA NA NA NA NA NA NA 4646 FUN_012785 50 2 21 0 166 NA NA NA NA NA NA NA 4647 FUN_044093 9 20 15 23 60 NA NA NA NA NA NA NA 4648 FUN_036229 355 764 175 232 217 ptg000025l:16816119-16819177 Q91X96 4.59e-24 Guanine nucleotide exchange factor MSS4 (Rab-interacting factor) Mus musculus (Mouse) post-Golgi vesicle-mediated transport [GO:0006892]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] GO:0005085; GO:0005829; GO:0006892; GO:0007264; GO:0008270; GO:0015031; GO:0016020 4649 FUN_036228 1657 1233 580 1619 1442 NA NA NA NA NA NA NA 4650 FUN_036221 2039 2263 864 1485 872 NA NA NA NA NA NA NA 4651 FUN_036220 0 221 0 91 44 NA NA NA NA NA NA NA 4652 FUN_036223 1916 2347 852 2360 1504 NA NA NA NA NA NA NA 4653 FUN_036222 32 49 61 126 72 ptg000025l:16745878-16748284 Q8IZU8 4.12e-96 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 4654 FUN_036222 32 49 61 126 72 ptg000025l:16745878-16748284 Q8IZU8 5.59e-25 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 4655 FUN_036225 1336 1496 714 1310 682 NA NA NA NA NA NA NA 4656 FUN_036224 47257 60064 21753 39071 36582 ptg000025l:16767188-16770066 Q90YV5 7.89e-28 60S ribosomal protein L13 Ictalurus punctatus (Channel catfish) (Silurus punctatus) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 4657 FUN_042988 335 2555 503 65 71 NA NA NA NA NA NA NA 4658 FUN_000040 6 14 62 49 175 NA NA NA NA NA NA NA 4659 FUN_000041 2 2 8 13 22 NA NA NA NA NA NA NA 4660 FUN_000042 4 3 8 18 29 NA NA NA NA NA NA NA 4661 FUN_000043 2 5 34 20 108 NA NA NA NA NA NA NA 4662 FUN_000044 0 1 9 11 25 NA NA NA NA NA NA NA 4663 FUN_000045 6 4 17 22 51 NA NA NA NA NA NA NA 4664 FUN_000047 2 1 4 0 23 ntLink_4:2660-3441 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4665 FUN_000048 1 0 0 1 6 ntLink_4:4515-6830 P35061 6.65e-78 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4666 FUN_000049 7 0 14 1 20 ntLink_4:7096-7859 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4667 FUN_037689 315 310 207 296 526 ptg000026l:12401555-12403974 Q5XI67 4.23e-50 F-box only protein 30 Rattus norvegicus (Rat) NA GO:0008270; GO:0061630 4668 FUN_006768 1201 1642 549 752 266 ptg000001l:16355748-16356737 Q07E02 8.78e-44 Caveolin-1 Ornithorhynchus anatinus (Duckbill platypus) caveola assembly [GO:0070836]; cell differentiation [GO:0030154]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of protein tyrosine kinase activity [GO:0061099]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; receptor internalization [GO:0031623]; regulation of cytosolic calcium ion concentration [GO:0051480]; T cell costimulation [GO:0031295] GO:0000139; GO:0001937; GO:0005768; GO:0005794; GO:0005886; GO:0005901; GO:0019901; GO:0030154; GO:0030512; GO:0031295; GO:0031410; GO:0031623; GO:0044325; GO:0045121; GO:0048471; GO:0051480; GO:0060090; GO:0061099; GO:0070836 4669 FUN_023670 193 70 94 124 164 NA NA NA NA NA NA NA 4670 FUN_013382 620 295 226 343 323 NA NA NA NA NA NA NA 4671 FUN_013381 2817 2449 980 1453 2068 NA NA NA NA NA NA NA 4672 FUN_030468 6 0 7 1 35 ptg000023l:10939164-10939927 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 4673 FUN_013380 2647 2312 2569 2716 1640 ptg000008l:21880056-21881047 Q5EA33 9.71e-22 Ankyrin repeat domain-containing protein 49 Bos taurus (Bovine) cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; spermatogenesis [GO:0007283] GO:0005634; GO:0005829; GO:0007283; GO:0030154; GO:0045893 4674 FUN_023674 286 161 93 230 190 NA NA NA NA NA NA NA 4675 FUN_023675 722 336 162 751 443 NA NA NA NA NA NA NA 4676 FUN_013385 2779 3498 3422 17060 7126 NA NA NA NA NA NA NA 4677 FUN_023677 541 441 199 904 618 NA NA NA NA NA NA NA 4678 FUN_006679 255 153 111 310 358 ptg000001l:15547124-15552390 Q3UY23 3.97e-26 Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog (FDX-ACDB domain-containing protein 1) Mus musculus (Mouse) rRNA base methylation [GO:0070475] GO:0005737; GO:0070042; GO:0070475 4679 FUN_006678 162 1360 263 549 436 NA NA NA NA NA NA NA 4680 FUN_008215 241 118 175 184 237 NA NA NA NA NA NA NA 4681 FUN_008214 1086 575 698 1156 903 ptg000002l:9344315-9362749 A0MQH0 5.59e-23 Endoribonuclease Dicer (EC 3.1.26.3) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) global gene silencing by mRNA cleavage [GO:0098795]; negative regulation of tumor necrosis factor production [GO:0032720]; NIK/NF-kappaB signaling [GO:0038061]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; siRNA processing [GO:0030422] GO:0003677; GO:0003725; GO:0004386; GO:0004525; GO:0005524; GO:0016442; GO:0019904; GO:0030422; GO:0031054; GO:0032720; GO:0035197; GO:0038061; GO:0046872; GO:0048471; GO:0070062; GO:0070578; GO:0070883; GO:0070922; GO:0098795 4682 FUN_008217 554 109 339 272 347 NA NA NA NA NA NA NA 4683 FUN_006672 859 159 101 317 81 NA NA NA NA NA NA NA 4684 FUN_006675 29 0 0 17 20 NA NA NA NA NA NA NA 4685 FUN_008210 183 129 83 209 179 NA NA NA NA NA NA NA 4686 FUN_008213 226 197 82 303 139 NA NA NA NA NA NA NA 4687 FUN_006676 346 0 0 78 0 NA NA NA NA NA NA NA 4688 FUN_016698 551 244 527 530 533 ptg000011l:6419322-6430289 P35409 1.75e-129 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 4689 FUN_016699 848 750 560 1020 503 NA NA NA NA NA NA NA 4690 FUN_016696 0 82 0 0 109 ptg000011l:6400812-6409061 A2RUC4 4.78e-30 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 4691 FUN_016696 0 82 0 0 109 ptg000011l:6400812-6409061 A2RUC4 3.66e-21 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 4692 FUN_016694 724 1792 340 438 703 NA NA NA NA NA NA NA 4693 FUN_016695 265 104 136 346 247 ptg000011l:6382691-6394003 P35409 1.67e-129 Probable glycoprotein hormone G-protein coupled receptor Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima) NA GO:0004930; GO:0005886; GO:0016500 4694 FUN_016692 0 0 51 70 16 ptg000011l:6328499-6329640 A2RSX7 1.63e-23 tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Mus musculus (Mouse) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0016706; GO:0031591; GO:0042803; GO:0102524 4695 FUN_016693 45 0 0 0 0 NA NA NA NA NA NA NA 4696 FUN_016690 227 3 37 56 72 ptg000011l:6313090-6318433 Q06496 1.8e-51 Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1) Rattus norvegicus (Rat) arsenate ion transmembrane transport [GO:1901684]; bone remodeling [GO:0046849]; calcium ion homeostasis [GO:0055074]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to metal ion [GO:0071248]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to phosphate starvation [GO:0016036]; cellular response to staurosporine [GO:0072734]; dentinogenesis [GO:0097187]; gene expression [GO:0010467]; gentamycin metabolic process [GO:1901128]; glycoprotein metabolic process [GO:0009100]; indole metabolic process [GO:0042431]; inorganic diphosphate transport [GO:0030505]; kidney development [GO:0001822]; ossification [GO:0001503]; phosphate ion homeostasis [GO:0055062]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; positive regulation of membrane potential [GO:0045838]; positive regulation of phosphate transmembrane transport [GO:2000187]; positive regulation of sodium-dependent phosphate transport [GO:2000120]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to growth hormone [GO:0060416]; response to lead ion [GO:0010288]; response to magnesium ion [GO:0032026]; response to mercury ion [GO:0046689]; response to nutrient [GO:0007584]; response to parathyroid hormone [GO:0071107]; response to peptide [GO:1901652]; response to peptide hormone [GO:0043434]; response to potassium ion [GO:0035864]; response to sodium phosphate [GO:1904383]; response to thyroid hormone [GO:0097066]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; sodium ion import across plasma membrane [GO:0098719]; sodium-dependent phosphate transport [GO:0044341]; tricarboxylic acid metabolic process [GO:0072350] GO:0001503; GO:0001822; GO:0005436; GO:0005768; GO:0005829; GO:0005886; GO:0005903; GO:0006817; GO:0007584; GO:0009100; GO:0009410; GO:0009986; GO:0010288; GO:0010467; GO:0016036; GO:0016323; GO:0016324; GO:0016607; GO:0030165; GO:0030505; GO:0030643; GO:0031526; GO:0031982; GO:0032026; GO:0032355; GO:0033189; GO:0035435; GO:0035864; GO:0042431; GO:0042802; GO:0043434; GO:0044341; GO:0044877; GO:0045121; GO:0045838; GO:0046686; GO:0046689; GO:0046849; GO:0048471; GO:0055062; GO:0055074; GO:0060416; GO:0071107; GO:0071248; GO:0071374; GO:0072350; GO:0072686; GO:0072734; GO:0097066; GO:0097187; GO:0098719; GO:1901128; GO:1901652; GO:1901684; GO:1904383; GO:2000120; GO:2000187 4697 FUN_016691 20 0 48 49 68 NA NA NA NA NA NA NA 4698 FUN_003531 0 0 0 0 19 NA NA NA NA NA NA NA 4699 FUN_004741 26 30 6 5 57 NA NA NA NA NA NA NA 4700 FUN_003532 6 0 1 0 16 NA NA NA NA NA NA NA 4701 FUN_003534 0 0 7 0 25 NA NA NA NA NA NA NA 4702 FUN_003537 0 0 14 0 0 NA NA NA NA NA NA NA 4703 FUN_004744 15 0 0 13 0 NA NA NA NA NA NA NA 4704 FUN_004748 1239 912 854 1307 1398 NA NA NA NA NA NA NA 4705 FUN_010223 0 12 0 22 0 NA NA NA NA NA NA NA 4706 FUN_010222 0 13 0 0 0 NA NA NA NA NA NA NA 4707 FUN_032830 716 696 371 534 339 NA NA NA NA NA NA NA 4708 FUN_032831 101 88 132 141 206 ptg000023l:36450800-36454186 Q9Y4W2 5.06e-21 Ribosomal biogenesis protein LAS1L (Protein LAS1 homolog) Homo sapiens (Human) maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470] GO:0000460; GO:0000470; GO:0003723; GO:0004519; GO:0005654; GO:0005730; GO:0016020; GO:0030687; GO:0071339; GO:0090730 4709 FUN_032832 3527 1787 1807 2790 3092 NA NA NA NA NA NA NA 4710 FUN_032833 752 416 355 904 1035 NA NA NA NA NA NA NA 4711 FUN_032834 56 21 53 156 88 ptg000023l:36479567-36485868 Q9GZV8 5.24e-74 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Homo sapiens (Human) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000902; GO:0000977; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0030718; GO:0031490; GO:0034972; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 4712 FUN_032835 93 64 107 55 70 NA NA NA NA NA NA NA 4713 FUN_032836 13 0 6 0 4 NA NA NA NA NA NA NA 4714 FUN_032837 56 36 22 12 12 ptg000023l:36509842-36510763 Q9MYW9 2.87e-21 Mu-type opioid receptor (M-OR-1) (MOR-1) Macaca mulatta (Rhesus macaque) adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway [GO:0007197]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of Wnt protein secretion [GO:0061358]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of neurogenesis [GO:0050769]; regulation of NMDA receptor activity [GO:2000310]; sensory perception of pain [GO:0019233] GO:0001965; GO:0004930; GO:0004979; GO:0005245; GO:0005768; GO:0005886; GO:0007197; GO:0007200; GO:0007218; GO:0019233; GO:0030424; GO:0030425; GO:0031681; GO:0038003; GO:0038047; GO:0042277; GO:0042923; GO:0043005; GO:0043204; GO:0043951; GO:0045019; GO:0045202; GO:0050769; GO:0051481; GO:0061358; GO:0070374; GO:2000310 4715 FUN_010597 329 5 331 373 306 NA NA NA NA NA NA NA 4716 FUN_040276 356 141 0 147 9 NA NA NA NA NA NA NA 4717 FUN_040275 22 6 0 49 0 NA NA NA NA NA NA NA 4718 FUN_040274 62 240 184 268 60 NA NA NA NA NA NA NA 4719 FUN_010593 2545 582 648 5208 1098 NA NA NA NA NA NA NA 4720 FUN_010592 262 161 208 340 291 NA NA NA NA NA NA NA 4721 FUN_040271 1269 584 601 752 1606 ptg000031l:6166127-6181241 Q59HJ6 7.36e-32 Lon protease homolog, mitochondrial (EC 3.4.21.53) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; chaperone-mediated protein complex assembly [GO:0051131]; mitochondrion organization [GO:0007005]; modification-dependent protein catabolic process [GO:0019941]; oxidation-dependent protein catabolic process [GO:0070407]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0003697; GO:0004176; GO:0004252; GO:0005524; GO:0005759; GO:0006515; GO:0007005; GO:0016887; GO:0019941; GO:0034599; GO:0043565; GO:0051131; GO:0070407 4722 FUN_010590 131 0 29 20 29 NA NA NA NA NA NA NA 4723 FUN_041898 2557 1647 1499 2208 2448 NA NA NA NA NA NA NA 4724 FUN_041899 119 110 82 85 115 NA NA NA NA NA NA NA 4725 FUN_041890 8516 9240 4991 7548 5826 NA NA NA NA NA NA NA 4726 FUN_041891 5 77 4 11 17 NA NA NA NA NA NA NA 4727 FUN_041892 217 60 4 599 177 ptg000035l:8685665-8688779 P16390 1.66e-107 Potassium voltage-gated channel subfamily A member 3 (MK3) (Voltage-gated potassium channel subunit Kv1.3) Mus musculus (Mouse) corpus callosum development [GO:0022038]; optic nerve development [GO:0021554]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0015271; GO:0016020; GO:0021554; GO:0022038; GO:0030424; GO:0034765; GO:0042734; GO:0044305; GO:0045121; GO:0045211; GO:0051260; GO:0071805; GO:0098978 4728 FUN_041893 7 5 0 0 0 NA NA NA NA NA NA NA 4729 FUN_041894 143 39 51 69 4 ptg000035l:8695454-8696615 Q09470 2.73e-95 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 4730 FUN_041895 2493 1642 1663 2323 2187 NA NA NA NA NA NA NA 4731 FUN_041896 15 220 25 52 27 ptg000035l:8713901-8716786 A8TSS9 5.27e-21 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Monopterus albus (Swamp eel) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0043565; GO:0046872 4732 FUN_041897 4977 4583 3331 4080 2212 ptg000035l:8717397-8722648 Q63486 1.01e-38 Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell death [GO:0008219]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; negative regulation of cytolysis [GO:0045918]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein localization [GO:0008104]; regulation of autophagy [GO:0010506]; regulation of TORC1 signaling [GO:1903432]; response to amino acid [GO:0043200]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0006915; GO:0008104; GO:0008219; GO:0009267; GO:0010506; GO:0010507; GO:0031625; GO:0032008; GO:0033209; GO:0034198; GO:0042803; GO:0043200; GO:0045918; GO:0046982; GO:0051219; GO:0071230; GO:1903432; GO:1904263; GO:1990130; GO:1990131 4733 FUN_041897 4977 4583 3331 4080 2212 ptg000035l:8717397-8722648 Q63486 1.86e-33 Ras-related GTP-binding protein A (Rag A) (RagA) (EC 3.6.5.-) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell death [GO:0008219]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; negative regulation of cytolysis [GO:0045918]; positive regulation of TOR signaling [GO:0032008]; positive regulation of TORC1 signaling [GO:1904263]; protein localization [GO:0008104]; regulation of autophagy [GO:0010506]; regulation of TORC1 signaling [GO:1903432]; response to amino acid [GO:0043200]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005764; GO:0006915; GO:0008104; GO:0008219; GO:0009267; GO:0010506; GO:0010507; GO:0031625; GO:0032008; GO:0033209; GO:0034198; GO:0042803; GO:0043200; GO:0045918; GO:0046982; GO:0051219; GO:0071230; GO:1903432; GO:1904263; GO:1990130; GO:1990131 4734 FUN_011172 0 59 0 15 0 ptg000007l:7115388-7131399 P14381 4.96e-38 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 4735 FUN_011172 0 59 0 15 0 ptg000007l:7115388-7131399 P14381 4.96e-38 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 4736 FUN_011177 23 11 3 12 11 NA NA NA NA NA NA NA 4737 FUN_011174 0 9 0 0 11 NA NA NA NA NA NA NA 4738 FUN_011178 512 177 96 76 98 NA NA NA NA NA NA NA 4739 FUN_011179 20 0 0 0 0 NA NA NA NA NA NA NA 4740 FUN_012269 10 0 23 0 0 NA NA NA NA NA NA NA 4741 FUN_012268 7 2 7 0 69 NA NA NA NA NA NA NA 4742 FUN_000369 495 303 618 1333 410 NA NA NA NA NA NA NA 4743 FUN_040851 0 0 0 0 6 NA NA NA NA NA NA NA 4744 FUN_040850 11 12 14 0 17 NA NA NA NA NA NA NA 4745 FUN_040857 247 327 187 158 216 NA NA NA NA NA NA NA 4746 FUN_040856 391 830 315 682 455 NA NA NA NA NA NA NA 4747 FUN_040855 29 7 8 12 30 NA NA NA NA NA NA NA 4748 FUN_040854 1152 620 375 561 469 NA NA NA NA NA NA NA 4749 FUN_040859 0 0 5 15 0 NA NA NA NA NA NA NA 4750 FUN_040858 7837 14798 7513 9710 5317 NA NA NA NA NA NA NA 4751 FUN_002378 1279 814 560 557 673 NA NA NA NA NA NA NA 4752 FUN_002379 3729 2539 1932 1969 1892 NA NA NA NA NA NA NA 4753 FUN_011265 0 0 0 0 17 NA NA NA NA NA NA NA 4754 FUN_002370 635 814 142 523 0 NA NA NA NA NA NA NA 4755 FUN_002371 79 74 0 0 33 NA NA NA NA NA NA NA 4756 FUN_002372 63 44 3 19 21 NA NA NA NA NA NA NA 4757 FUN_002373 0 8 0 3 3 NA NA NA NA NA NA NA 4758 FUN_002375 357 66 49 57 41 NA NA NA NA NA NA NA 4759 FUN_002376 80 13 145 31 175 NA NA NA NA NA NA NA 4760 FUN_002377 819 527 228 568 220 NA NA NA NA NA NA NA 4761 FUN_012265 5009 4628 4082 3484 2684 NA NA NA NA NA NA NA 4762 FUN_012264 258 176 305 267 295 ptg000008l:7015413-7017576 E7FAM5 1.69e-40 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 4763 FUN_011268 247 191 411 208 233 NA NA NA NA NA NA NA 4764 FUN_011269 264 219 262 75 190 NA NA NA NA NA NA NA 4765 FUN_029412 890 876 648 1073 1426 NA NA NA NA NA NA NA 4766 FUN_029413 2786 1938 1366 2982 3369 NA NA NA NA NA NA NA 4767 FUN_029410 2037 1522 897 2010 1261 ptg000023l:1582755-1585054 P09041 0 Phosphoglycerate kinase 2 (EC 2.7.2.3) (Phosphoglycerate kinase, testis specific) Mus musculus (Mouse) flagellated sperm motility [GO:0030317]; gluconeogenesis [GO:0006094]; glycolytic process [GO:0006096]; phosphorylation [GO:0016310] GO:0004618; GO:0005524; GO:0005829; GO:0005929; GO:0006094; GO:0006096; GO:0016310; GO:0030317; GO:0035686; GO:0043531 4768 FUN_029411 14 47 15 8 21 NA NA NA NA NA NA NA 4769 FUN_029416 197 0 124 171 258 NA NA NA NA NA NA NA 4770 FUN_029417 1145 536 179 5 662 NA NA NA NA NA NA NA 4771 FUN_029414 5235 3495 1596 3063 2688 ptg000023l:1617979-1689001 P42285 1.87e-29 Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; maturation of 5.8S rRNA [GO:0000460]; mRNA splicing, via spliceosome [GO:0000398]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; snRNA catabolic process [GO:0016076] GO:0000398; GO:0000460; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0006401; GO:0006974; GO:0016076; GO:0016607; GO:0016887; GO:0031499; GO:0071013 4772 FUN_029414 5235 3495 1596 3063 2688 ptg000023l:1617979-1689001 P42285 1.87e-29 Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; maturation of 5.8S rRNA [GO:0000460]; mRNA splicing, via spliceosome [GO:0000398]; RNA catabolic process [GO:0006401]; rRNA processing [GO:0006364]; snRNA catabolic process [GO:0016076] GO:0000398; GO:0000460; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006364; GO:0006401; GO:0006974; GO:0016076; GO:0016607; GO:0016887; GO:0031499; GO:0071013 4773 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 2.33e-43 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4774 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 5.89e-41 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4775 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 7.35e-41 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4776 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 8.86e-41 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4777 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 4.56e-40 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4778 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 4.64e-40 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4779 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 3.19e-39 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4780 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 5.97e-39 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4781 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.91e-38 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4782 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 2.15e-38 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4783 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 3.11e-37 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4784 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 8.25e-37 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4785 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.36e-36 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4786 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.99e-36 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4787 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 2.87e-36 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4788 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 3.15e-36 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4789 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 4.53e-36 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4790 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 6.75e-36 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4791 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 3.46e-35 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4792 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.44e-34 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4793 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 9.58e-34 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4794 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.47e-33 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4795 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.78e-33 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4796 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 8.58e-33 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4797 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 3.8e-32 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4798 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.25e-31 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4799 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 3.9e-31 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4800 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 9.83e-29 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4801 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 1.64e-24 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4802 FUN_029415 7 0 2 9 568 ptg000023l:1692369-1696050 Q96WV6 9.54e-23 Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) NA GO:0009897; GO:0010339; GO:0098631 4803 FUN_029418 12239 10690 6182 5486 8516 NA NA NA NA NA NA NA 4804 FUN_029419 701 676 352 532 959 NA NA NA NA NA NA NA 4805 FUN_038433 1280 569 904 1144 557 NA NA NA NA NA NA NA 4806 FUN_016335 0 0 0 0 16 NA NA NA NA NA NA NA 4807 FUN_016334 13597 16205 7965 11523 7451 NA NA NA NA NA NA NA 4808 FUN_016337 1463 720 571 1288 1084 NA NA NA NA NA NA NA 4809 FUN_016336 148 64 0 109 53 NA NA NA NA NA NA NA 4810 FUN_016331 2258 1118 1422 2472 2484 ptg000011l:1692448-1716810 P16086 7.13e-27 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 4811 FUN_016331 2258 1118 1422 2472 2484 ptg000011l:1692448-1716810 P16086 7.13e-27 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 4812 FUN_016331 2258 1118 1422 2472 2484 ptg000011l:1692448-1716810 P16086 2.85e-24 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 4813 FUN_016331 2258 1118 1422 2472 2484 ptg000011l:1692448-1716810 P16086 2.19e-22 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 4814 FUN_016331 2258 1118 1422 2472 2484 ptg000011l:1692448-1716810 P16086 2.84e-22 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 4815 FUN_016331 2258 1118 1422 2472 2484 ptg000011l:1692448-1716810 P16086 7.11e-21 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005829; GO:0005886; GO:0005916; GO:0008091; GO:0016020; GO:0016328; GO:0019905; GO:0030018; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030864; GO:0031532; GO:0032437; GO:0032991; GO:0033010; GO:0033270; GO:0042995; GO:0044877; GO:0051015; GO:0051693; GO:0098794; GO:0098978 4816 FUN_016333 7493 5120 3727 6562 4874 NA NA NA NA NA NA NA 4817 FUN_016332 769 490 456 590 982 NA NA NA NA NA NA NA 4818 FUN_003290 0 0 0 4 16 NA NA NA NA NA NA NA 4819 FUN_016338 3716 4131 1890 2659 2754 NA NA NA NA NA NA NA 4820 FUN_015678 7 0 11 0 7 NA NA NA NA NA NA NA 4821 FUN_015674 117 101 13 94 114 NA NA NA NA NA NA NA 4822 FUN_015676 20 8 0 0 3 NA NA NA NA NA NA NA 4823 FUN_015671 0 39 0 0 0 NA NA NA NA NA NA NA 4824 FUN_015673 0 0 0 2 18 NA NA NA NA NA NA NA 4825 FUN_015672 353 169 29 261 299 NA NA NA NA NA NA NA 4826 FUN_023151 0 14 0 0 6 NA NA NA NA NA NA NA 4827 FUN_026305 7404 4901 4425 7192 5644 NA NA NA NA NA NA NA 4828 FUN_026303 4100 4670 1860 6721 2721 NA NA NA NA NA NA NA 4829 FUN_023154 3 0 3 2 18 NA NA NA NA NA NA NA 4830 FUN_026300 667 105 144 635 211 NA NA NA NA NA NA NA 4831 FUN_023159 10750 12315 9548 10406 5068 NA NA NA NA NA NA NA 4832 FUN_023158 14300 7971 6395 9749 6281 ptg000017l:4312720-4327582 O97578 7.16e-31 Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] Canis lupus familiaris (Dog) (Canis familiaris) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0008239; GO:0051603 4833 FUN_023158 14300 7971 6395 9749 6281 ptg000017l:4312720-4327582 O97578 6.09e-27 Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] Canis lupus familiaris (Dog) (Canis familiaris) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0008239; GO:0051603 4834 FUN_023158 14300 7971 6395 9749 6281 ptg000017l:4312720-4327582 O97578 7.07e-26 Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] Canis lupus familiaris (Dog) (Canis familiaris) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0008239; GO:0051603 4835 FUN_023158 14300 7971 6395 9749 6281 ptg000017l:4312720-4327582 O97578 1.73e-24 Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain 1 (Dipeptidyl peptidase I heavy chain 1); Dipeptidyl peptidase 1 heavy chain 2 (Dipeptidyl peptidase I heavy chain 2); Dipeptidyl peptidase 1 heavy chain 3 (Dipeptidyl peptidase I heavy chain 3); Dipeptidyl peptidase 1 heavy chain 4 (Dipeptidyl peptidase I heavy chain 4); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)] Canis lupus familiaris (Dog) (Canis familiaris) proteolysis involved in protein catabolic process [GO:0051603] GO:0004197; GO:0005615; GO:0005764; GO:0008239; GO:0051603 4836 FUN_026309 263 280 90 154 133 ptg000020l:7644465-7654384 Q14585 4.98e-120 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 4837 FUN_026309 263 280 90 154 133 ptg000020l:7644465-7654384 Q14585 2.72e-118 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 4838 FUN_026309 263 280 90 154 133 ptg000020l:7644465-7654384 Q14585 3.88e-114 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 4839 FUN_026309 263 280 90 154 133 ptg000020l:7644465-7654384 Q14585 7.88e-90 Zinc finger protein 345 (Zinc finger protein HZF10) Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription by RNA polymerase III [GO:0006359]; transcription by RNA polymerase II [GO:0006366]; transcription by RNA polymerase III [GO:0006383] GO:0000122; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0006359; GO:0006366; GO:0006383; GO:0046872; GO:1990837 4840 FUN_026308 2398 1318 823 1911 803 NA NA NA NA NA NA NA 4841 FUN_025654 546 227 188 470 714 NA NA NA NA NA NA NA 4842 FUN_022687 212 137 127 166 199 NA NA NA NA NA NA NA 4843 FUN_025656 1265 898 504 835 534 NA NA NA NA NA NA NA 4844 FUN_025650 1423 605 777 713 564 NA NA NA NA NA NA NA 4845 FUN_025651 4380 3605 2301 3471 2937 ptg000019l:5245061-5259127 O35904 2.68e-46 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.137) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta) Mus musculus (Mouse) adaptive immune response [GO:0002250]; B cell activation [GO:0042113]; B cell homeostasis [GO:0001782]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; cell surface receptor signaling pathway [GO:0007166]; chemotaxis [GO:0006935]; defense response to fungus [GO:0050832]; homeostasis of number of cells [GO:0048872]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; phosphatidylinositol 3-kinase signaling [GO:0014065]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; phosphatidylinositol-mediated signaling [GO:0048015]; phosphorylation [GO:0016310]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration by vascular endothelial growth factor signaling pathway [GO:0038089]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial tube formation [GO:1905278]; positive regulation of gene expression [GO:0010628]; positive regulation of neutrophil apoptotic process [GO:0033031]; positive regulation of protein kinase B signaling [GO:0051897] GO:0001782; GO:0001938; GO:0002250; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005942; GO:0005943; GO:0006935; GO:0006954; GO:0007166; GO:0010595; GO:0010628; GO:0010629; GO:0014065; GO:0016020; GO:0016301; GO:0016303; GO:0016310; GO:0016477; GO:0030154; GO:0030335; GO:0033031; GO:0035005; GO:0036092; GO:0038089; GO:0042113; GO:0045087; GO:0045766; GO:0046854; GO:0046934; GO:0048015; GO:0048872; GO:0050832; GO:0051897; GO:0052742; GO:0052812; GO:1905278 4846 FUN_022680 0 0 2 0 6 NA NA NA NA NA NA NA 4847 FUN_025658 4019 2441 2019 3643 2598 NA NA NA NA NA NA NA 4848 FUN_025659 27125 31409 14169 24462 18892 NA NA NA NA NA NA NA 4849 FUN_022688 1406 1318 843 1471 1593 NA NA NA NA NA NA NA 4850 FUN_022689 1269 960 556 1056 959 NA NA NA NA NA NA NA 4851 FUN_023489 330 156 247 313 200 ptg000017l:8145757-8146903 P25931 1.27e-23 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 4852 FUN_023488 0 0 0 15 6 NA NA NA NA NA NA NA 4853 FUN_041072 23 0 52 6 0 NA NA NA NA NA NA NA 4854 FUN_023481 15 8 0 0 0 ptg000017l:8029175-8030233 B8VIU6 3.87e-22 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4855 FUN_023487 20 0 0 8 105 ptg000017l:8122739-8131796 B8VIU6 6.17e-23 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4856 FUN_023486 0 0 0 0 32 NA NA NA NA NA NA NA 4857 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 1.82e-50 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4858 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 4.92e-48 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4859 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 4.92e-48 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4860 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 4.92e-48 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4861 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 1.41e-47 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4862 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 8.29e-32 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4863 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 9.71e-32 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4864 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 1.01e-31 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4865 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 1.01e-31 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4866 FUN_041074 0 0 46 0 94 ptg000034l:466207-484287 B8WI85 1.01e-31 Uncharacterized skeletal organic matrix protein 7 (Uncharacterized SOMP-7) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 4867 FUN_023484 130 0 96 23 34 NA NA NA NA NA NA NA 4868 FUN_028455 569 608 142 686 1233 NA NA NA NA NA NA NA 4869 FUN_028454 380 412 178 982 520 NA NA NA NA NA NA NA 4870 FUN_028457 130 0 63 18 39 NA NA NA NA NA NA NA 4871 FUN_028456 198 384 213 262 591 NA NA NA NA NA NA NA 4872 FUN_028451 322 52 148 261 530 NA NA NA NA NA NA NA 4873 FUN_028450 4215 3052 2790 5763 4607 ptg000021l:20128773-20181688 Q09575 6.01e-24 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 4874 FUN_028453 74 449 302 1580 1096 NA NA NA NA NA NA NA 4875 FUN_028452 118 10412 112 8645 2345 NA NA NA NA NA NA NA 4876 FUN_028458 0 0 0 38 0 NA NA NA NA NA NA NA 4877 FUN_043033 1558 1042 907 1867 1573 ptg000047l:3188298-3227031 P14381 1.99e-102 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 4878 FUN_043034 301 172 195 573 197 NA NA NA NA NA NA NA 4879 FUN_043035 632 126 176 186 71 NA NA NA NA NA NA NA 4880 FUN_011958 1048 701 644 1467 2010 NA NA NA NA NA NA NA 4881 FUN_011959 1143 915 758 986 949 NA NA NA NA NA NA NA 4882 FUN_011955 337 312 288 211 214 NA NA NA NA NA NA NA 4883 FUN_011956 331 193 186 252 344 ptg000008l:3541890-3544366 Q0V8R7 1.27e-22 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) Bos taurus (Bovine) RNA methylation [GO:0001510]; rRNA methylation [GO:0031167] GO:0001510; GO:0005762; GO:0008168; GO:0019843; GO:0031167 4884 FUN_011957 1973 1602 1303 2028 2177 NA NA NA NA NA NA NA 4885 FUN_011950 790 600 335 923 1052 ptg000008l:3452791-3453928 Q5XIV0 1.9e-142 Terminal nucleotidyltransferase 5C (EC 2.7.7.19) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; mRNA stabilization [GO:0048255]; negative regulation of cell differentiation [GO:0045596] GO:0001701; GO:0003723; GO:0004652; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0045596; GO:0048255; GO:1990817 4886 FUN_011951 775 419 352 512 428 ptg000008l:3459362-3475516 A7T167 1.61e-30 Protein GDAP2 homolog Nematostella vectensis (Starlet sea anemone) NA NA 4887 FUN_011952 1958 1422 1190 2908 2291 NA NA NA NA NA NA NA 4888 FUN_011953 658 473 220 488 914 NA NA NA NA NA NA NA 4889 FUN_019411 4 37 115 71 121 NA NA NA NA NA NA NA 4890 FUN_013087 0 0 6 0 0 NA NA NA NA NA NA NA 4891 FUN_008158 54 0 0 39 40 NA NA NA NA NA NA NA 4892 FUN_008159 0 0 0 0 16 NA NA NA NA NA NA NA 4893 FUN_022520 3428 2913 2336 2281 2069 NA NA NA NA NA NA NA 4894 FUN_008152 67 89 100 144 101 NA NA NA NA NA NA NA 4895 FUN_008153 32 14 24 2 137 NA NA NA NA NA NA NA 4896 FUN_008150 17 0 14 14 30 NA NA NA NA NA NA NA 4897 FUN_008151 79 202 91 76 56 NA NA NA NA NA NA NA 4898 FUN_008156 0 88 0 0 35 NA NA NA NA NA NA NA 4899 FUN_008157 38 29 53 98 56 NA NA NA NA NA NA NA 4900 FUN_008154 84 127 67 83 77 NA NA NA NA NA NA NA 4901 FUN_044169 2 0 6 9 19 NA NA NA NA NA NA NA 4902 FUN_014203 0 6 5 2 3 NA NA NA NA NA NA NA 4903 FUN_014202 17 0 0 0 2 NA NA NA NA NA NA NA 4904 FUN_014201 16 0 0 12 11 NA NA NA NA NA NA NA 4905 FUN_014200 0 0 0 0 6 NA NA NA NA NA NA NA 4906 FUN_044167 4 0 5 5 11 NA NA NA NA NA NA NA 4907 FUN_044166 5 3 41 32 149 NA NA NA NA NA NA NA 4908 FUN_014205 0 0 0 0 7 NA NA NA NA NA NA NA 4909 FUN_044164 3 5 41 50 104 NA NA NA NA NA NA NA 4910 FUN_022358 575 158 320 319 318 ptg000016l:8031280-8078883 P55013 3.15e-54 Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter) Squalus acanthias (Spiny dogfish) inorganic cation import across plasma membrane [GO:0098659]; potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] GO:0006813; GO:0006814; GO:0015377; GO:0016323; GO:0046873; GO:0071944; GO:0098659 4911 FUN_022358 575 158 320 319 318 ptg000016l:8031280-8078883 P55013 9.18e-48 Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter) Squalus acanthias (Spiny dogfish) inorganic cation import across plasma membrane [GO:0098659]; potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] GO:0006813; GO:0006814; GO:0015377; GO:0016323; GO:0046873; GO:0071944; GO:0098659 4912 FUN_022358 575 158 320 319 318 ptg000016l:8031280-8078883 P55013 4.13e-45 Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter) Squalus acanthias (Spiny dogfish) inorganic cation import across plasma membrane [GO:0098659]; potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] GO:0006813; GO:0006814; GO:0015377; GO:0016323; GO:0046873; GO:0071944; GO:0098659 4913 FUN_022358 575 158 320 319 318 ptg000016l:8031280-8078883 P55013 3.95e-44 Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter) Squalus acanthias (Spiny dogfish) inorganic cation import across plasma membrane [GO:0098659]; potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] GO:0006813; GO:0006814; GO:0015377; GO:0016323; GO:0046873; GO:0071944; GO:0098659 4914 FUN_022358 575 158 320 319 318 ptg000016l:8031280-8078883 P55013 5.33e-44 Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter) Squalus acanthias (Spiny dogfish) inorganic cation import across plasma membrane [GO:0098659]; potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] GO:0006813; GO:0006814; GO:0015377; GO:0016323; GO:0046873; GO:0071944; GO:0098659 4915 FUN_022358 575 158 320 319 318 ptg000016l:8031280-8078883 P55013 1.37e-43 Solute carrier family 12 member 2 (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1) (NKCC) (Na-K-CL symporter) Squalus acanthias (Spiny dogfish) inorganic cation import across plasma membrane [GO:0098659]; potassium ion transport [GO:0006813]; sodium ion transport [GO:0006814] GO:0006813; GO:0006814; GO:0015377; GO:0016323; GO:0046873; GO:0071944; GO:0098659 4916 FUN_022359 671 686 497 746 769 NA NA NA NA NA NA NA 4917 FUN_022350 48 42 12 71 110 NA NA NA NA NA NA NA 4918 FUN_022351 21 43 19 1 24 NA NA NA NA NA NA NA 4919 FUN_022352 0 10 0 1 17 NA NA NA NA NA NA NA 4920 FUN_022353 24 617 22 90 263 NA NA NA NA NA NA NA 4921 FUN_022354 2802 1865 1533 2270 2159 NA NA NA NA NA NA NA 4922 FUN_022355 109 228 0 0 149 NA NA NA NA NA NA NA 4923 FUN_022356 356 303 57 98 226 NA NA NA NA NA NA NA 4924 FUN_022357 290 1294 89 254 1218 ptg000016l:8003202-8022147 A0A0G2KTI4 1.63e-58 Solute carrier family 12 member 2 (Na-K-Cl cotransporter 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell volume homeostasis [GO:0006884]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; ear development [GO:0043583]; inner ear morphogenesis [GO:0042472]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; sodium ion homeostasis [GO:0055078]; sodium ion transmembrane transport [GO:0035725]; swim bladder inflation [GO:0048798] GO:0006884; GO:0008511; GO:0008519; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0035725; GO:0042472; GO:0042802; GO:0043583; GO:0048798; GO:0055064; GO:0055075; GO:0055078; GO:1902476; GO:1990573 4925 FUN_022357 290 1294 89 254 1218 ptg000016l:8003202-8022147 A0A0G2KTI4 7.34e-46 Solute carrier family 12 member 2 (Na-K-Cl cotransporter 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell volume homeostasis [GO:0006884]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; ear development [GO:0043583]; inner ear morphogenesis [GO:0042472]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; sodium ion homeostasis [GO:0055078]; sodium ion transmembrane transport [GO:0035725]; swim bladder inflation [GO:0048798] GO:0006884; GO:0008511; GO:0008519; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0035725; GO:0042472; GO:0042802; GO:0043583; GO:0048798; GO:0055064; GO:0055075; GO:0055078; GO:1902476; GO:1990573 4926 FUN_022357 290 1294 89 254 1218 ptg000016l:8003202-8022147 A0A0G2KTI4 2.21e-41 Solute carrier family 12 member 2 (Na-K-Cl cotransporter 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell volume homeostasis [GO:0006884]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; ear development [GO:0043583]; inner ear morphogenesis [GO:0042472]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; sodium ion homeostasis [GO:0055078]; sodium ion transmembrane transport [GO:0035725]; swim bladder inflation [GO:0048798] GO:0006884; GO:0008511; GO:0008519; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0035725; GO:0042472; GO:0042802; GO:0043583; GO:0048798; GO:0055064; GO:0055075; GO:0055078; GO:1902476; GO:1990573 4927 FUN_024219 811 689 289 543 760 NA NA NA NA NA NA NA 4928 FUN_024218 585 797 627 527 467 NA NA NA NA NA NA NA 4929 FUN_024217 2381 1397 1030 2344 1514 NA NA NA NA NA NA NA 4930 FUN_024216 3166 2129 1824 2487 1559 NA NA NA NA NA NA NA 4931 FUN_024215 4504 4250 2571 2854 2500 NA NA NA NA NA NA NA 4932 FUN_024214 1369 1956 1285 1579 1584 NA NA NA NA NA NA NA 4933 FUN_024213 766 120 190 208 201 ptg000018l:3509230-3512787 P59046 1e-52 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 4934 FUN_024211 0 0 0 7 0 NA NA NA NA NA NA NA 4935 FUN_024210 1272 2421 1701 1726 1660 NA NA NA NA NA NA NA 4936 FUN_044299 6 16 8 11 40 NA NA NA NA NA NA NA 4937 FUN_044298 1 0 8 1 24 NA NA NA NA NA NA NA 4938 FUN_044295 5 7 11 2 66 NA NA NA NA NA NA NA 4939 FUN_044294 0 0 2 0 8 NA NA NA NA NA NA NA 4940 FUN_044296 0 0 0 9 18 NA NA NA NA NA NA NA 4941 FUN_044293 2 8 5 7 13 NA NA NA NA NA NA NA 4942 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 2.72e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4943 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 5.86e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4944 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 8.1e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4945 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 5.16e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4946 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 1.05e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4947 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 2.58e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4948 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 3.58e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4949 FUN_044292 15 47 19 70 23 ptg000142l:956-6404 Q96AY4 1.27e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 4950 FUN_029597 10 0 0 0 0 NA NA NA NA NA NA NA 4951 FUN_036100 1835 954 745 2096 1535 ptg000025l:15393380-15395370 Q0P8I7 3.68e-48 GDP-D-glycero-alpha-D-manno-heptose dehydrogenase (EC 1.1.98.-) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) capsule polysaccharide biosynthetic process [GO:0045227]; protein homotetramerization [GO:0051289] GO:0003978; GO:0016491; GO:0019003; GO:0042802; GO:0045227; GO:0051289; GO:0070404 4952 FUN_031333 0 11 17 9 8 NA NA NA NA NA NA NA 4953 FUN_031330 31 29 34 0 43 NA NA NA NA NA NA NA 4954 FUN_036103 2319 2897 2115 1624 1788 ptg000025l:15411799-15415565 P54357 5.26e-33 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 4955 FUN_036104 2083 1708 1034 1814 2069 ptg000025l:15418495-15433876 Q28001 2.48e-47 Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) Bos taurus (Bovine) alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] GO:0006836; GO:0008021; GO:0015293; GO:0015804; GO:0015816; GO:0015820; GO:0015824; GO:0016020; GO:0030672; GO:0032328; GO:0035725; GO:0042995; GO:0098794 4956 FUN_022441 49 99 47 137 243 NA NA NA NA NA NA NA 4957 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 3.52e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4958 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 3.52e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4959 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 6.67e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4960 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 6.56e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4961 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 1.91e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4962 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 2.45e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4963 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 6.54e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4964 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 1.53e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4965 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 2.34e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4966 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 1.63e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4967 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 1.76e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4968 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 2.07e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4969 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 1.52e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4970 FUN_031334 203 96 747 110 1293 ptg000023l:19728287-19740123 Q7RTR2 2.94e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 4971 FUN_036107 99 131 32 87 72 NA NA NA NA NA NA NA 4972 FUN_043213 653 2331 1328 1528 1303 NA NA NA NA NA NA NA 4973 FUN_000488 14627 24467 25662 19245 22402 ntLink_6:3544456-3548865 Q963B6 1.35e-36 60S ribosomal protein L10a Spodoptera frugiperda (Fall armyworm) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015934 4974 FUN_000488 14627 24467 25662 19245 22402 ntLink_6:3544456-3548865 Q963B6 7.89e-22 60S ribosomal protein L10a Spodoptera frugiperda (Fall armyworm) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015934 4975 FUN_022443 0 0 32 45 41 ptg000016l:9066179-9073698 P41383 1.54e-68 Tubulin alpha-2/alpha-4 chain (EC 3.6.5.-) Patella vulgata (Common limpet) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 4976 FUN_022443 0 0 32 45 41 ptg000016l:9066179-9073698 P41383 3.06e-57 Tubulin alpha-2/alpha-4 chain (EC 3.6.5.-) Patella vulgata (Common limpet) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 4977 FUN_022443 0 0 32 45 41 ptg000016l:9066179-9073698 P41383 8.59e-45 Tubulin alpha-2/alpha-4 chain (EC 3.6.5.-) Patella vulgata (Common limpet) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 4978 FUN_022443 0 0 32 45 41 ptg000016l:9066179-9073698 P41383 1.41e-39 Tubulin alpha-2/alpha-4 chain (EC 3.6.5.-) Patella vulgata (Common limpet) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 4979 FUN_022443 0 0 32 45 41 ptg000016l:9066179-9073698 P41383 1.31e-22 Tubulin alpha-2/alpha-4 chain (EC 3.6.5.-) Patella vulgata (Common limpet) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 4980 FUN_029594 1550 445 484 684 494 ptg000023l:3567454-3579812 E7FAM5 4.45e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 4981 FUN_029594 1550 445 484 684 494 ptg000023l:3567454-3579812 E7FAM5 9.49e-22 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 4982 FUN_023973 1358 980 1149 4536 2325 NA NA NA NA NA NA NA 4983 FUN_023972 2367 1362 842 1912 1493 NA NA NA NA NA NA NA 4984 FUN_023971 1524 1591 810 1636 1112 ptg000018l:692226-695712 P22739 1.85e-58 Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (xSHA2) Xenopus laevis (African clawed frog) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 4985 FUN_023975 38 29 0 134 39 NA NA NA NA NA NA NA 4986 FUN_023974 410 39 174 259 318 NA NA NA NA NA NA NA 4987 FUN_031617 0 0 17 0 0 NA NA NA NA NA NA NA 4988 FUN_031616 40 0 29 11 0 NA NA NA NA NA NA NA 4989 FUN_031611 57 69 65 60 68 NA NA NA NA NA NA NA 4990 FUN_022103 1221 826 583 1385 685 NA NA NA NA NA NA NA 4991 FUN_039104 12 0 0 0 16 NA NA NA NA NA NA NA 4992 FUN_039446 3 0 0 0 34 NA NA NA NA NA NA NA 4993 FUN_039448 0 2 2 0 95 NA NA NA NA NA NA NA 4994 FUN_025732 3205 1439 930 1952 2415 NA NA NA NA NA NA NA 4995 FUN_025731 275 200 238 430 321 NA NA NA NA NA NA NA 4996 FUN_025730 4551 2576 2396 5099 3926 ptg000020l:169408-185971 B0VXE6 1.42e-23 Cilia- and flagella-associated protein 69 Callithrix jacchus (White-tufted-ear marmoset) cell differentiation [GO:0030154]; olfactory behavior [GO:0042048]; positive regulation of fertilization [GO:1905516]; positive regulation of flagellated sperm motility [GO:1902093]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; spermatogenesis [GO:0007283] GO:0005737; GO:0007283; GO:0007608; GO:0030154; GO:0042048; GO:0097225; GO:0097730; GO:1902093; GO:1905516; GO:1990834 4997 FUN_025730 4551 2576 2396 5099 3926 ptg000020l:169408-185971 B0VXE6 1.42e-23 Cilia- and flagella-associated protein 69 Callithrix jacchus (White-tufted-ear marmoset) cell differentiation [GO:0030154]; olfactory behavior [GO:0042048]; positive regulation of fertilization [GO:1905516]; positive regulation of flagellated sperm motility [GO:1902093]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; spermatogenesis [GO:0007283] GO:0005737; GO:0007283; GO:0007608; GO:0030154; GO:0042048; GO:0097225; GO:0097730; GO:1902093; GO:1905516; GO:1990834 4998 FUN_022446 2165 1666 5379 4409 2902 ptg000016l:9086809-9095624 Q29496 2.03e-70 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 4999 FUN_022447 282 948 153 106 394 NA NA NA NA NA NA NA 5000 FUN_024464 1180 183 593 416 418 ptg000018l:6694366-6696425 Q99LB6 1.31e-21 Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) Mus musculus (Mouse) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0005634; GO:0005739; GO:0006556; GO:0006730; GO:0019899; GO:0048269; GO:0048270 5001 FUN_024464 1180 183 593 416 418 ptg000018l:6694366-6696425 Q99LB6 1.31e-21 Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) Mus musculus (Mouse) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0005634; GO:0005739; GO:0006556; GO:0006730; GO:0019899; GO:0048269; GO:0048270 5002 FUN_024465 122 212 66 81 6 NA NA NA NA NA NA NA 5003 FUN_008077 468 276 350 483 603 NA NA NA NA NA NA NA 5004 FUN_026842 0 10 11 0 151 NA NA NA NA NA NA NA 5005 FUN_026843 11 0 32 0 172 NA NA NA NA NA NA NA 5006 FUN_026844 9 0 0 0 80 NA NA NA NA NA NA NA 5007 FUN_026846 0 278 7 20 243 NA NA NA NA NA NA NA 5008 FUN_026847 0 72 0 39 35 NA NA NA NA NA NA NA 5009 FUN_008071 67 30 53 95 22 NA NA NA NA NA NA NA 5010 FUN_008070 330 508 192 342 336 NA NA NA NA NA NA NA 5011 FUN_008073 474 134 91 237 237 NA NA NA NA NA NA NA 5012 FUN_008072 64 38 27 135 67 NA NA NA NA NA NA NA 5013 FUN_037510 519 282 344 558 640 NA NA NA NA NA NA NA 5014 FUN_037511 200 58 102 184 259 NA NA NA NA NA NA NA 5015 FUN_037513 32 0 0 14 0 NA NA NA NA NA NA NA 5016 FUN_037514 13 0 34 4 21 NA NA NA NA NA NA NA 5017 FUN_037515 15 21 0 33 18 NA NA NA NA NA NA NA 5018 FUN_037516 102 24 37 85 60 NA NA NA NA NA NA NA 5019 FUN_037517 279 106 132 157 205 ptg000026l:11317875-11324755 A4IGP0 3.21e-37 Protein Hikeshi Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to heat [GO:0034605]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0006606; GO:0015031; GO:0030544; GO:0034605 5020 FUN_037517 279 106 132 157 205 ptg000026l:11317875-11324755 A4IGP0 1.41e-21 Protein Hikeshi Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to heat [GO:0034605]; protein import into nucleus [GO:0006606]; protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0006606; GO:0015031; GO:0030544; GO:0034605 5021 FUN_037518 84 17 0 27 45 NA NA NA NA NA NA NA 5022 FUN_037519 630 617 267 682 522 ptg000026l:11341129-11344964 A7RF00 8.19e-72 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) Nematostella vectensis (Starlet sea anemone) L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284] GO:0005634; GO:0005737; GO:0019284; GO:0019509; GO:0046523 5023 FUN_037519 630 617 267 682 522 ptg000026l:11341129-11344964 A7RF00 3.74e-23 Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein) Nematostella vectensis (Starlet sea anemone) L-methionine salvage from methylthioadenosine [GO:0019509]; L-methionine salvage from S-adenosylmethionine [GO:0019284] GO:0005634; GO:0005737; GO:0019284; GO:0019509; GO:0046523 5024 FUN_024468 363 329 117 973 73 NA NA NA NA NA NA NA 5025 FUN_024469 295 217 41 494 102 NA NA NA NA NA NA NA 5026 FUN_039896 100 88 134 97 50 NA NA NA NA NA NA NA 5027 FUN_030988 286 0 162 280 302 NA NA NA NA NA NA NA 5028 FUN_030989 0 0 12 0 0 NA NA NA NA NA NA NA 5029 FUN_030986 269 0 50 0 9 NA NA NA NA NA NA NA 5030 FUN_030987 100 0 17 47 46 NA NA NA NA NA NA NA 5031 FUN_030985 71 0 23 10 0 NA NA NA NA NA NA NA 5032 FUN_030345 5 0 6 1 19 ptg000023l:10653098-10653861 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5033 FUN_000237 489 192 200 391 212 NA NA NA NA NA NA NA 5034 FUN_040649 3 0 0 1 23 NA NA NA NA NA NA NA 5035 FUN_010123 9 0 0 5 24 NA NA NA NA NA NA NA 5036 FUN_004239 292 344 231 242 418 NA NA NA NA NA NA NA 5037 FUN_004238 1096 824 694 812 629 NA NA NA NA NA NA NA 5038 FUN_033989 4930 2971 2525 5322 4188 NA NA NA NA NA NA NA 5039 FUN_033988 719 752 431 546 504 NA NA NA NA NA NA NA 5040 FUN_004233 4213 5288 3454 4535 2218 NA NA NA NA NA NA NA 5041 FUN_033985 412 556 260 378 553 NA NA NA NA NA NA NA 5042 FUN_004230 176 491 1346 414 884 NA NA NA NA NA NA NA 5043 FUN_033983 5 8 2 16 11 NA NA NA NA NA NA NA 5044 FUN_033982 1173 913 531 1160 697 NA NA NA NA NA NA NA 5045 FUN_004235 348 515 470 676 488 ntLink_8:20992167-20993444 Q6UXP7 5.12e-50 Protein FAM151B Homo sapiens (Human) NA GO:0005615 5046 FUN_004234 270 130 209 481 47 NA NA NA NA NA NA NA 5047 FUN_010124 32 0 0 0 5 NA NA NA NA NA NA NA 5048 FUN_025296 4433 7772 1044 3185 1660 NA NA NA NA NA NA NA 5049 FUN_016028 12 13 8 8 2 NA NA NA NA NA NA NA 5050 FUN_019137 437 429 460 386 214 ptg000012l:17636872-17637526 P56224 4.78e-77 POU domain, class 3, transcription factor 3-A (Brain-specific homeobox/POU domain protein 1.1) (Brain-1.1) (zfBrn-1.1) (Class III POU domain protein taichi) (POU domain protein 12) (ZP-12) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007420 5051 FUN_033957 1882 1586 1250 1814 1213 ptg000024l:3129674-3137401 Q8BGS7 1.82e-39 Choline/ethanolaminephosphotransferase 1 (mCEPT1) (EC 2.7.8.1) (EC 2.7.8.2) (1-alkenyl-2-acylglycerol choline phosphotransferase) (EC 2.7.8.22) Mus musculus (Mouse) phosphatidylcholine biosynthetic process [GO:0006656]; phosphatidylethanolamine biosynthetic process [GO:0006646] GO:0004142; GO:0004307; GO:0005789; GO:0005794; GO:0006646; GO:0006656; GO:0016780; GO:0031965; GO:0046872; GO:0047359 5052 FUN_019135 405 256 256 452 621 NA NA NA NA NA NA NA 5053 FUN_019132 62 48 11 37 6 NA NA NA NA NA NA NA 5054 FUN_019133 43 0 4 42 9 NA NA NA NA NA NA NA 5055 FUN_019130 126 136 66 113 128 NA NA NA NA NA NA NA 5056 FUN_019131 175 258 133 137 110 NA NA NA NA NA NA NA 5057 FUN_000123 2 1 8 1 15 ntLink_4:178147-178910 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5058 FUN_019138 134 30 0 97 130 NA NA NA NA NA NA NA 5059 FUN_019139 1494 1403 1022 1773 1107 NA NA NA NA NA NA NA 5060 FUN_016021 26 6 14 237 84 NA NA NA NA NA NA NA 5061 FUN_016020 238 185 66 288 298 NA NA NA NA NA NA NA 5062 FUN_042343 0 0 0 0 6 NA NA NA NA NA NA NA 5063 FUN_042342 0 0 0 0 16 NA NA NA NA NA NA NA 5064 FUN_016025 0 0 57 18 9 NA NA NA NA NA NA NA 5065 FUN_042344 0 0 0 0 6 NA NA NA NA NA NA NA 5066 FUN_030204 2 0 2 0 10 ptg000023l:10361291-10362054 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5067 FUN_030206 3 0 3 0 7 ptg000023l:10365343-10366106 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5068 FUN_021188 0 12 2 3 26 NA NA NA NA NA NA NA 5069 FUN_021189 0 33 41 16 33 NA NA NA NA NA NA NA 5070 FUN_030203 18 3 15 0 64 ptg000023l:10351020-10354756 Q6LAF1 4.33e-48 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 5071 FUN_030202 235 140 86 236 126 NA NA NA NA NA NA NA 5072 FUN_021184 0 1 0 0 16 NA NA NA NA NA NA NA 5073 FUN_021186 0 0 0 0 20 NA NA NA NA NA NA NA 5074 FUN_021181 0 0 0 0 14 NA NA NA NA NA NA NA 5075 FUN_021183 0 5 0 0 30 NA NA NA NA NA NA NA 5076 FUN_025293 19 24 20 51 18 NA NA NA NA NA NA NA 5077 FUN_021453 321 237 257 395 337 NA NA NA NA NA NA NA 5078 FUN_021450 497 597 135 140 175 NA NA NA NA NA NA NA 5079 FUN_021451 2040 1729 1229 1707 1597 NA NA NA NA NA NA NA 5080 FUN_035794 0 0 0 0 7 NA NA NA NA NA NA NA 5081 FUN_023702 784 301 334 762 497 NA NA NA NA NA NA NA 5082 FUN_021458 61 99 34 36 18 NA NA NA NA NA NA NA 5083 FUN_021459 0 0 0 0 23 NA NA NA NA NA NA NA 5084 FUN_037278 4086 2846 1458 3855 1715 NA NA NA NA NA NA NA 5085 FUN_031558 0 24 2 0 21 ptg000023l:22843913-22845274 Q6PBX9 7.08e-41 Receptor expression-enhancing protein 5 Danio rerio (Zebrafish) (Brachydanio rerio) endoplasmic reticulum membrane organization [GO:0090158] GO:0033017; GO:0090158 5086 FUN_031559 802 424 453 479 538 NA NA NA NA NA NA NA 5087 FUN_031552 2990 3784 2319 2934 3095 NA NA NA NA NA NA NA 5088 FUN_031553 458 599 294 441 647 NA NA NA NA NA NA NA 5089 FUN_031550 587 193 171 242 147 NA NA NA NA NA NA NA 5090 FUN_031551 455 161 184 503 343 ptg000023l:22792432-22794067 P56433 4.67e-42 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 5091 FUN_031556 136 64 29 99 188 ptg000023l:22832058-22837688 Q6DD45 9.33e-42 Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8) Xenopus laevis (African clawed frog) ncRNA processing [GO:0034470] GO:0003676; GO:0005654; GO:0008270; GO:0034470 5092 FUN_031557 67 157 34 90 117 ptg000023l:22841037-22841946 Q8BH75 4.76e-23 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Mus musculus (Mouse) autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0000209; GO:0004842; GO:0005128; GO:0005135; GO:0006914; GO:0008270; GO:0008285; GO:0010498; GO:0016567; GO:0019904; GO:0030336; GO:0030971; GO:0031267; GO:0042802; GO:0043408; GO:0045619; GO:0045637; GO:0045732; GO:0048471; GO:0051865; GO:0051896; GO:0061630; GO:0071782; GO:0097191; GO:1901525; GO:2000377; GO:2000379 5093 FUN_031554 22 0 40 2 61 NA NA NA NA NA NA NA 5094 FUN_031555 98 31 56 17 56 NA NA NA NA NA NA NA 5095 FUN_040452 71 0 74 36 0 NA NA NA NA NA NA NA 5096 FUN_040450 109 121 125 74 67 NA NA NA NA NA NA NA 5097 FUN_037895 22 0 0 0 0 NA NA NA NA NA NA NA 5098 FUN_040459 7 0 0 0 0 NA NA NA NA NA NA NA 5099 FUN_037896 442 226 416 353 410 ptg000027l:235355-258409 Q7TN88 8.08e-50 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 5100 FUN_018245 1773 1601 290 1207 1497 ptg000012l:6562510-6585844 Q96AY4 1.84e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5101 FUN_018245 1773 1601 290 1207 1497 ptg000012l:6562510-6585844 Q96AY4 3.39e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5102 FUN_018245 1773 1601 290 1207 1497 ptg000012l:6562510-6585844 Q96AY4 3.95e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5103 FUN_018244 0 24 0 0 0 NA NA NA NA NA NA NA 5104 FUN_032119 98 13 32 0 47 NA NA NA NA NA NA NA 5105 FUN_032118 7492 12266 8047 15350 8869 ptg000023l:28976787-28994297 P21328 2.64e-40 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 5106 FUN_010127 3 0 2 8 5 NA NA NA NA NA NA NA 5107 FUN_032113 15552 15225 5906 14546 9014 NA NA NA NA NA NA NA 5108 FUN_032112 802 586 457 1183 639 NA NA NA NA NA NA NA 5109 FUN_032111 1156 1200 964 1471 1528 ptg000023l:28932741-28936456 A3KMX8 5.48e-72 Damage-control phosphatase ARMT1 (EC 3.1.3.-) (Acidic residue methyltransferase 1) (Protein-glutamate O-methyltransferase) (EC 2.1.1.-) (Sugar phosphate phosphatase ARMT1) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; methylation [GO:0032259]; regulation of response to DNA damage stimulus [GO:2001020] GO:0006974; GO:0008757; GO:0008983; GO:0016791; GO:0032259; GO:0046872; GO:0051998; GO:0097023; GO:0103026; GO:2001020 5110 FUN_032110 3833 8231 2008 2057 1097 ptg000023l:28929390-28932288 Q8K4M5 1.55e-45 COMM domain-containing protein 1 (Protein Murr1) Mus musculus (Mouse) cellular copper ion homeostasis [GO:0006878]; cholesterol homeostasis [GO:0042632]; copper ion homeostasis [GO:0055070]; Golgi to plasma membrane transport [GO:0006893]; low-density lipoprotein particle clearance [GO:0034383]; negative regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902072]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of sodium ion transmembrane transport [GO:1902306]; nucleotide-excision repair [GO:0006289]; plasma membrane to endosome transport [GO:0048227]; positive regulation of cholesterol import [GO:1904109]; positive regulation of endosome to plasma membrane protein transport [GO:1905751]; positive regulation of protein localization to cell surface [GO:2000010]; positive regulation of protein ubiquitination [GO:0031398]; protein destabilization [GO:0031648]; protein localization to cell surface [GO:0034394]; protein transport [GO:0015031]; regulation of plasma lipoprotein particle levels [GO:0097006]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434] GO:0005507; GO:0005546; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005829; GO:0006289; GO:0006878; GO:0006893; GO:0010008; GO:0015031; GO:0019871; GO:0031398; GO:0031462; GO:0031648; GO:0032088; GO:0032434; GO:0034383; GO:0034394; GO:0042632; GO:0042802; GO:0042803; GO:0043325; GO:0048227; GO:0050750; GO:0055037; GO:0055070; GO:0070300; GO:0080025; GO:0097006; GO:1902072; GO:1902306; GO:1904109; GO:1905751; GO:2000009; GO:2000010 5111 FUN_032117 4707 2937 2237 4072 3575 ptg000023l:28961320-28974961 Q80U96 1.47e-72 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) Rattus norvegicus (Rat) cellular response to salt [GO:1902075]; cellular response to triglyceride [GO:0071401]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization [GO:0008104]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to xenobiotic stimulus [GO:0009410]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] GO:0000054; GO:0000055; GO:0000056; GO:0000122; GO:0000776; GO:0003723; GO:0005049; GO:0005634; GO:0005642; GO:0005730; GO:0005737; GO:0006611; GO:0006913; GO:0008104; GO:0009410; GO:0010824; GO:0015030; GO:0019904; GO:0031267; GO:0032434; GO:0032991; GO:0034504; GO:0042176; GO:0042254; GO:0046825; GO:0051028; GO:0071401; GO:0140297; GO:1902075; GO:1990904 5112 FUN_032117 4707 2937 2237 4072 3575 ptg000023l:28961320-28974961 Q80U96 2.54e-23 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) Rattus norvegicus (Rat) cellular response to salt [GO:1902075]; cellular response to triglyceride [GO:0071401]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization [GO:0008104]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to xenobiotic stimulus [GO:0009410]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] GO:0000054; GO:0000055; GO:0000056; GO:0000122; GO:0000776; GO:0003723; GO:0005049; GO:0005634; GO:0005642; GO:0005730; GO:0005737; GO:0006611; GO:0006913; GO:0008104; GO:0009410; GO:0010824; GO:0015030; GO:0019904; GO:0031267; GO:0032434; GO:0032991; GO:0034504; GO:0042176; GO:0042254; GO:0046825; GO:0051028; GO:0071401; GO:0140297; GO:1902075; GO:1990904 5113 FUN_032117 4707 2937 2237 4072 3575 ptg000023l:28961320-28974961 Q80U96 2.54e-23 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) Rattus norvegicus (Rat) cellular response to salt [GO:1902075]; cellular response to triglyceride [GO:0071401]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization [GO:0008104]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to xenobiotic stimulus [GO:0009410]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] GO:0000054; GO:0000055; GO:0000056; GO:0000122; GO:0000776; GO:0003723; GO:0005049; GO:0005634; GO:0005642; GO:0005730; GO:0005737; GO:0006611; GO:0006913; GO:0008104; GO:0009410; GO:0010824; GO:0015030; GO:0019904; GO:0031267; GO:0032434; GO:0032991; GO:0034504; GO:0042176; GO:0042254; GO:0046825; GO:0051028; GO:0071401; GO:0140297; GO:1902075; GO:1990904 5114 FUN_032117 4707 2937 2237 4072 3575 ptg000023l:28961320-28974961 Q80U96 2.51e-21 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) Rattus norvegicus (Rat) cellular response to salt [GO:1902075]; cellular response to triglyceride [GO:0071401]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization [GO:0008104]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to xenobiotic stimulus [GO:0009410]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] GO:0000054; GO:0000055; GO:0000056; GO:0000122; GO:0000776; GO:0003723; GO:0005049; GO:0005634; GO:0005642; GO:0005730; GO:0005737; GO:0006611; GO:0006913; GO:0008104; GO:0009410; GO:0010824; GO:0015030; GO:0019904; GO:0031267; GO:0032434; GO:0032991; GO:0034504; GO:0042176; GO:0042254; GO:0046825; GO:0051028; GO:0071401; GO:0140297; GO:1902075; GO:1990904 5115 FUN_032117 4707 2937 2237 4072 3575 ptg000023l:28961320-28974961 Q80U96 2.51e-21 Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) Rattus norvegicus (Rat) cellular response to salt [GO:1902075]; cellular response to triglyceride [GO:0071401]; mRNA transport [GO:0051028]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleocytoplasmic transport [GO:0006913]; protein export from nucleus [GO:0006611]; protein localization [GO:0008104]; protein localization to nucleus [GO:0034504]; regulation of centrosome duplication [GO:0010824]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of protein catabolic process [GO:0042176]; regulation of protein export from nucleus [GO:0046825]; response to xenobiotic stimulus [GO:0009410]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; ribosomal subunit export from nucleus [GO:0000054]; ribosome biogenesis [GO:0042254] GO:0000054; GO:0000055; GO:0000056; GO:0000122; GO:0000776; GO:0003723; GO:0005049; GO:0005634; GO:0005642; GO:0005730; GO:0005737; GO:0006611; GO:0006913; GO:0008104; GO:0009410; GO:0010824; GO:0015030; GO:0019904; GO:0031267; GO:0032434; GO:0032991; GO:0034504; GO:0042176; GO:0042254; GO:0046825; GO:0051028; GO:0071401; GO:0140297; GO:1902075; GO:1990904 5116 FUN_032116 94 119 95 63 81 NA NA NA NA NA NA NA 5117 FUN_032115 1210 822 757 774 914 ptg000023l:28955610-28958003 Q1LYE3 8.73e-36 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0045893; GO:0046872 5118 FUN_032115 1210 822 757 774 914 ptg000023l:28955610-28958003 Q1LYE3 1.62e-29 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0045893; GO:0046872 5119 FUN_032115 1210 822 757 774 914 ptg000023l:28955610-28958003 Q1LYE3 8.04e-26 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0045893; GO:0046872 5120 FUN_032115 1210 822 757 774 914 ptg000023l:28955610-28958003 Q1LYE3 3.47e-25 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0045893; GO:0046872 5121 FUN_032114 6664 8123 7296 15495 10959 NA NA NA NA NA NA NA 5122 FUN_007965 906 1024 669 813 735 NA NA NA NA NA NA NA 5123 FUN_017227 42 1 34 10 237 NA NA NA NA NA NA NA 5124 FUN_008398 947 474 506 1243 638 NA NA NA NA NA NA NA 5125 FUN_008399 819 733 749 1264 815 NA NA NA NA NA NA NA 5126 FUN_008390 697 420 418 576 475 NA NA NA NA NA NA NA 5127 FUN_008391 304 162 132 120 265 NA NA NA NA NA NA NA 5128 FUN_008392 611 535 378 407 341 ptg000002l:11071412-11073584 Q9Y2I1 4.94e-61 Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; negative regulation of cell migration [GO:0030336]; Rac protein signal transduction [GO:0016601] GO:0005178; GO:0005654; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006915; GO:0015630; GO:0016020; GO:0016601; GO:0019901; GO:0030036; GO:0030336; GO:0035091; GO:0042802; GO:0043231; GO:0045171; GO:0055037 5129 FUN_008393 7 10 11 4 16 NA NA NA NA NA NA NA 5130 FUN_008394 4187 3466 2178 2987 2580 NA NA NA NA NA NA NA 5131 FUN_008395 446 458 335 126 312 NA NA NA NA NA NA NA 5132 FUN_008396 4942 2812 2152 3418 4014 ptg000002l:11083477-11098559 Q28FH2 5.02e-27 N-terminal kinase-like protein (SCY1-like protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0006468 5133 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 1.1e-142 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5134 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 9.41e-136 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5135 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 1.22e-134 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5136 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 1.81e-133 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5137 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 4.48e-133 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5138 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 1.35e-125 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5139 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 3.48e-124 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5140 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 6.58e-120 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5141 FUN_008397 32725 11848 14476 52078 44442 ptg000002l:11102969-11120995 Q09666 2.8e-83 Neuroblast differentiation-associated protein AHNAK (Desmoyokin) Homo sapiens (Human) positive regulation of plasma membrane repair [GO:1905686]; regulation of RNA splicing [GO:0043484]; regulation of voltage-gated calcium channel activity [GO:1901385] GO:0003723; GO:0005634; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0005925; GO:0015629; GO:0016020; GO:0030315; GO:0031982; GO:0042383; GO:0042802; GO:0043034; GO:0043484; GO:0044291; GO:0044548; GO:0045296; GO:0070062; GO:0097493; GO:0098797; GO:1901385; GO:1905686 5142 FUN_043904 0 15 0 18 12 NA NA NA NA NA NA NA 5143 FUN_043906 0 0 0 0 22 NA NA NA NA NA NA NA 5144 FUN_043907 0 16 0 0 85 NA NA NA NA NA NA NA 5145 FUN_043900 0 0 23 10 0 NA NA NA NA NA NA NA 5146 FUN_043901 153 79 20 55 42 NA NA NA NA NA NA NA 5147 FUN_043902 145 559 85 743 372 NA NA NA NA NA NA NA 5148 FUN_043903 10 0 0 76 35 NA NA NA NA NA NA NA 5149 FUN_043909 37 3 3 378 28 NA NA NA NA NA NA NA 5150 FUN_007719 136 98 0 0 19 NA NA NA NA NA NA NA 5151 FUN_002949 0 26 15 0 0 NA NA NA NA NA NA NA 5152 FUN_007715 0 92 0 0 0 NA NA NA NA NA NA NA 5153 FUN_007714 18 2240 0 7 9 ptg000002l:3720327-3796907 Q99315 7.47e-103 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 5154 FUN_007714 18 2240 0 7 9 ptg000002l:3720327-3796907 Q99315 3.19e-66 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 5155 FUN_041469 246 131 46 64 114 NA NA NA NA NA NA NA 5156 FUN_013948 0 0 0 10 4 NA NA NA NA NA NA NA 5157 FUN_041461 163 259 39 63 10 ptg000035l:3870227-3870842 Q7SY75 9.61e-67 Neurocalcin-delta Xenopus laevis (African clawed frog) NA GO:0005509 5158 FUN_041460 898 496 303 845 720 ptg000035l:3853330-3866231 Q68FP9 3.89e-24 Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) Rattus norvegicus (Rat) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0006891; GO:0007030; GO:0015031; GO:0017119; GO:0070085 5159 FUN_041460 898 496 303 845 720 ptg000035l:3853330-3866231 Q68FP9 3.89e-24 Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6) Rattus norvegicus (Rat) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0006891; GO:0007030; GO:0015031; GO:0017119; GO:0070085 5160 FUN_038746 18 0 68 0 163 NA NA NA NA NA NA NA 5161 FUN_028979 935 492 388 1165 789 ptg000022l:6712089-6734600 O43623 5.77e-53 Zinc finger protein SNAI2 (Neural crest transcription factor Slug) (Protein snail homolog 2) Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; cartilage morphogenesis [GO:0060536]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to ionizing radiation [GO:0071479]; desmosome disassembly [GO:0035921]; endothelial cell migration [GO:0043542]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; epithelium development [GO:0060429]; hematopoietic stem cell proliferation [GO:0071425]; myeloid cell apoptotic process [GO:0033028]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of hematopoietic stem cell proliferation [GO:1902034]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; negative regulation of vitamin D receptor signaling pathway [GO:0070563]; neural crest cell development [GO:0014032]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; osteoblast differentiation [GO:0001649]; pigmentation [GO:0043473]; positive regulation of cell migration [GO:0030335]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of histone acetylation [GO:0035066]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of chemokine production [GO:0032642]; regulation of DNA-templated transcription [GO:0006355]; regulation of osteoblast differentiation [GO:0045667]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; white fat cell differentiation [GO:0050872] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001649; GO:0001837; GO:0003180; GO:0003198; GO:0003273; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006355; GO:0006933; GO:0007219; GO:0007605; GO:0010839; GO:0010957; GO:0014032; GO:0030335; GO:0032331; GO:0032642; GO:0033028; GO:0033033; GO:0033629; GO:0035066; GO:0035921; GO:0043473; GO:0043518; GO:0043542; GO:0043565; GO:0045600; GO:0045667; GO:0046872; GO:0050872; GO:0060021; GO:0060429; GO:0060536; GO:0060693; GO:0061314; GO:0070563; GO:0070888; GO:0071364; GO:0071425; GO:0071479; GO:0090090; GO:1902034; GO:1902230; GO:1990837; GO:2000810; GO:2000811; GO:2001240 5162 FUN_003430 17 0 0 0 7 NA NA NA NA NA NA NA 5163 FUN_026232 385 1 44 7 44 NA NA NA NA NA NA NA 5164 FUN_029184 347 426 168 887 216 ptg000022l:9095039-9107664 Q0UL22 1.27e-34 Dicer-like protein 2 [Includes: Endoribonuclease DCL2 (EC 3.1.26.-); ATP-dependent helicase DCL2 (EC 3.6.4.-)] Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum) defense response to virus [GO:0051607]; regulation of defense response to virus [GO:0050688]; RNA phosphodiester bond hydrolysis [GO:0090501]; siRNA processing [GO:0030422] GO:0003723; GO:0004386; GO:0004525; GO:0005524; GO:0005634; GO:0005737; GO:0016442; GO:0030422; GO:0046872; GO:0050688; GO:0051607; GO:0090501 5165 FUN_015033 4 6 3 4 3 NA NA NA NA NA NA NA 5166 FUN_029186 714 393 424 504 530 NA NA NA NA NA NA NA 5167 FUN_003433 401 2273 1725 695 317 NA NA NA NA NA NA NA 5168 FUN_029180 408 317 215 415 376 ptg000022l:9040224-9068295 A2RAF3 2.93e-35 Dicer-like protein 1 [Includes: Endoribonuclease dcl1 (EC 3.1.26.-); ATP-dependent helicase dcl1 (EC 3.6.4.-)] Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) defense response to virus [GO:0051607]; regulation of defense response to virus [GO:0050688]; RNA processing [GO:0006396] GO:0003677; GO:0003723; GO:0004386; GO:0004525; GO:0005524; GO:0006396; GO:0046872; GO:0050688; GO:0051607 5169 FUN_029181 215 155 168 156 300 ptg000022l:9077277-9081826 Q8LMR2 8.52e-35 Endoribonuclease Dicer homolog 1 (Dicer-like protein 1) (OsDCL1) (EC 3.1.26.-) Oryza sativa subsp. japonica (Rice) miRNA processing [GO:0035196]; siRNA processing [GO:0030422] GO:0003723; GO:0004386; GO:0004525; GO:0005524; GO:0005634; GO:0005737; GO:0030422; GO:0035196; GO:0046872 5170 FUN_029182 194 110 133 203 279 ptg000022l:9082094-9085587 Q9LQV2 5.94e-24 RNA-dependent RNA polymerase 1 (AtRDRP1) (EC 2.7.7.48) (RNA-directed RNA polymerase 1) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0006952; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 5171 FUN_029183 476 788 396 425 518 NA NA NA NA NA NA NA 5172 FUN_003434 410 324 191 274 218 NA NA NA NA NA NA NA 5173 FUN_029188 1267 1365 650 1655 672 ptg000022l:9130844-9134575 P70677 2.58e-48 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (LICE) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mus musculus (Mouse) anterior neural tube closure [GO:0061713]; apoptotic process [GO:0006915]; axonal fasciculation [GO:0007413]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to organic substance [GO:0071310]; cellular response to staurosporine [GO:0072734]; epithelial cell apoptotic process [GO:1904019]; erythrocyte differentiation [GO:0030218]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast apoptotic process [GO:0044346]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; hippocampus development [GO:0021766]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; learning or memory [GO:0007611]; leukocyte apoptotic process [GO:0071887]; luteolysis [GO:0001554]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of apoptotic process [GO:0043066]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell cycle [GO:0045786]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic DNA fragmentation [GO:1902512]; positive regulation of apoptotic process [GO:0043065]; positive regulation of neuron apoptotic process [GO:0043525]; protein catabolic process [GO:0030163]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647]; response to amino acid [GO:0043200]; response to antibiotic [GO:0046677]; response to cobalt ion [GO:0032025]; response to estradiol [GO:0032355]; response to glucocorticoid [GO:0051384]; response to glucose [GO:0009749]; response to hydrogen peroxide [GO:0042542]; response to hypoxia [GO:0001666]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to organic substance [GO:0010033]; response to UV [GO:0009411]; response to wounding [GO:0009611]; response to X-ray [GO:0010165]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; striated muscle cell differentiation [GO:0051146]; T cell homeostasis [GO:0043029]; wound healing [GO:0042060] GO:0001554; GO:0001666; GO:0001782; GO:0002020; GO:0004175; GO:0004190; GO:0004197; GO:0004861; GO:0005123; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006974; GO:0007413; GO:0007507; GO:0007605; GO:0007611; GO:0008233; GO:0008234; GO:0008303; GO:0008627; GO:0009410; GO:0009411; GO:0009611; GO:0009749; GO:0010033; GO:0010165; GO:0016005; GO:0016485; GO:0021766; GO:0030163; GO:0030182; GO:0030216; GO:0030218; GO:0030889; GO:0031264; GO:0031647; GO:0032025; GO:0032355; GO:0032496; GO:0034349; GO:0035094; GO:0035556; GO:0042060; GO:0042542; GO:0043025; GO:0043029; GO:0043065; GO:0043066; GO:0043200; GO:0043525; GO:0044346; GO:0044877; GO:0045121; GO:0045165; GO:0045736; GO:0045786; GO:0046007; GO:0046677; GO:0048011; GO:0051146; GO:0051384; GO:0051402; GO:0061713; GO:0070059; GO:0071310; GO:0071887; GO:0072734; GO:0097153; GO:0097191; GO:0097193; GO:0097194; GO:0097199; GO:0097200; GO:1902004; GO:1902512; GO:1904019 5174 FUN_029189 1126 878 604 951 620 ptg000022l:9137729-9140078 Q5IS99 1.57e-49 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Saimiri boliviensis boliviensis (Bolivian squirrel monkey) cellular response to staurosporine [GO:0072734]; erythrocyte differentiation [GO:0030218]; intracellular signal transduction [GO:0035556]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005634; GO:0005829; GO:0006508; GO:0030218; GO:0031647; GO:0035556; GO:0048011; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004 5175 FUN_003435 36 29 0 20 24 NA NA NA NA NA NA NA 5176 FUN_033792 847 443 530 673 611 NA NA NA NA NA NA NA 5177 FUN_033793 799 592 819 1816 625 NA NA NA NA NA NA NA 5178 FUN_033790 2288 1532 1612 4257 2970 NA NA NA NA NA NA NA 5179 FUN_033791 1 7 0 2 57 NA NA NA NA NA NA NA 5180 FUN_033796 5813 6321 2764 6098 1323 NA NA NA NA NA NA NA 5181 FUN_033797 3398 2566 2250 4076 3204 NA NA NA NA NA NA NA 5182 FUN_033794 18 32 10 9 0 NA NA NA NA NA NA NA 5183 FUN_033795 130 30 82 146 54 NA NA NA NA NA NA NA 5184 FUN_015037 71 104 109 97 288 NA NA NA NA NA NA NA 5185 FUN_033798 536 411 212 700 666 ptg000024l:1512346-1524184 D4A055 2.24e-26 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Rattus norvegicus (Rat) adult walking behavior [GO:0007628]; calcium ion transport [GO:0006816]; cAMP metabolic process [GO:0046058]; cellular calcium ion homeostasis [GO:0006874]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005245; GO:0005730; GO:0005737; GO:0005886; GO:0005891; GO:0006816; GO:0006874; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0008331; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0042391; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050877; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:0099635; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 5186 FUN_033798 536 411 212 700 666 ptg000024l:1512346-1524184 D4A055 2.24e-26 Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) Rattus norvegicus (Rat) adult walking behavior [GO:0007628]; calcium ion transport [GO:0006816]; cAMP metabolic process [GO:0046058]; cellular calcium ion homeostasis [GO:0006874]; cellular response to leukemia inhibitory factor [GO:1990830]; chemical synaptic transmission [GO:0007268]; detection of light stimulus involved in visual perception [GO:0050908]; gamma-aminobutyric acid secretion [GO:0014051]; gamma-aminobutyric acid signaling pathway [GO:0007214]; muscle cell development [GO:0055001]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; nervous system process [GO:0050877]; neuromuscular junction development [GO:0007528]; neuronal action potential propagation [GO:0019227]; Peyer's patch development [GO:0048541]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of voltage-gated calcium channel activity [GO:1901387]; regulation of membrane potential [GO:0042391]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of voltage-gated calcium channel activity [GO:1901385]; spleen development [GO:0048536]; synaptic transmission, glutamatergic [GO:0035249]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538] GO:0005245; GO:0005730; GO:0005737; GO:0005886; GO:0005891; GO:0006816; GO:0006874; GO:0007214; GO:0007268; GO:0007528; GO:0007628; GO:0008285; GO:0008331; GO:0014051; GO:0016607; GO:0019227; GO:0019901; GO:0035249; GO:0042391; GO:0046058; GO:0048536; GO:0048538; GO:0048541; GO:0050852; GO:0050877; GO:0050908; GO:0055001; GO:0098793; GO:0098978; GO:0099626; GO:0099635; GO:1901385; GO:1901387; GO:1904751; GO:1990830; GO:2000134; GO:2000300 5187 FUN_028977 5979 3293 2855 6261 4624 NA NA NA NA NA NA NA 5188 FUN_015035 321 310 114 310 155 NA NA NA NA NA NA NA 5189 FUN_023137 96 69 37 119 34 ptg000017l:4063929-4066020 Q96PQ7 1.46e-27 Kelch-like protein 5 Homo sapiens (Human) NA GO:0003779; GO:0005737; GO:0005829; GO:0005856 5190 FUN_028975 275 98 100 362 291 NA NA NA NA NA NA NA 5191 FUN_003702 22943 8938 2458 4600 3231 NA NA NA NA NA NA NA 5192 FUN_003700 15952 10842 2332 4421 2111 NA NA NA NA NA NA NA 5193 FUN_003708 737 537 1741 3193 246 NA NA NA NA NA NA NA 5194 FUN_003709 2324 2446 3042 3912 2156 NA NA NA NA NA NA NA 5195 FUN_012304 18 15 0 0 16 NA NA NA NA NA NA NA 5196 FUN_012305 3267 2019 1038 2497 1877 ptg000008l:7691388-7696372 Q9NW07 1.17e-53 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 5197 FUN_012305 3267 2019 1038 2497 1877 ptg000008l:7691388-7696372 Q9NW07 9.28e-50 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 5198 FUN_012305 3267 2019 1038 2497 1877 ptg000008l:7691388-7696372 Q9NW07 4.46e-47 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 5199 FUN_012305 3267 2019 1038 2497 1877 ptg000008l:7691388-7696372 Q9NW07 3.08e-46 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 5200 FUN_012305 3267 2019 1038 2497 1877 ptg000008l:7691388-7696372 Q9NW07 1.89e-36 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 5201 FUN_012306 52 30 12 53 45 NA NA NA NA NA NA NA 5202 FUN_012307 2242 1067 906 1439 1236 NA NA NA NA NA NA NA 5203 FUN_012300 137 26 70 40 113 NA NA NA NA NA NA NA 5204 FUN_012301 4017 2853 1798 2957 2583 ptg000008l:7648903-7657768 Q5ZK88 1.24e-26 Paraspeckle component 1 Gallus gallus (Chicken) activation of innate immune response [GO:0002218]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; rhythmic process [GO:0048511] GO:0001650; GO:0002218; GO:0003723; GO:0005634; GO:0005737; GO:0006355; GO:0016363; GO:0016607; GO:0042382; GO:0042752; GO:0045892; GO:0048511 5205 FUN_012302 1020 562 641 551 689 NA NA NA NA NA NA NA 5206 FUN_012303 875 497 452 768 860 NA NA NA NA NA NA NA 5207 FUN_012308 5447 2643 2789 5281 4707 NA NA NA NA NA NA NA 5208 FUN_012309 63 0 26 19 18 NA NA NA NA NA NA NA 5209 FUN_028275 33418 1308 4632 36815 17423 ptg000021l:17508432-17519280 P49961 2e-44 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0007155; GO:0007596; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0070062 5210 FUN_028277 2444 2389 1644 2888 2625 NA NA NA NA NA NA NA 5211 FUN_028276 92 56 16 48 155 NA NA NA NA NA NA NA 5212 FUN_028271 89 102 121 68 64 NA NA NA NA NA NA NA 5213 FUN_028273 382 64 80 150 162 ptg000021l:17500076-17501336 P49961 5.2e-42 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (EC 3.6.1.5) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39) Homo sapiens (Human) blood coagulation [GO:0007596]; cell adhesion [GO:0007155]; nucleoside diphosphate catabolic process [GO:0009134] GO:0004382; GO:0005524; GO:0005886; GO:0007155; GO:0007596; GO:0009134; GO:0016020; GO:0017110; GO:0045134; GO:0070062 5214 FUN_028272 673 345 287 332 249 NA NA NA NA NA NA NA 5215 FUN_028279 2016 634 352 1333 745 NA NA NA NA NA NA NA 5216 FUN_028278 0 5 29 2 0 NA NA NA NA NA NA NA 5217 FUN_034223 1504 1338 850 1613 1396 NA NA NA NA NA NA NA 5218 FUN_034222 47 25 4 111 212 NA NA NA NA NA NA NA 5219 FUN_034221 24 17 40 26 163 NA NA NA NA NA NA NA 5220 FUN_034220 144 27 53 33 98 NA NA NA NA NA NA NA 5221 FUN_034227 21 0 0 16 208 NA NA NA NA NA NA NA 5222 FUN_034226 0 0 0 0 12 NA NA NA NA NA NA NA 5223 FUN_034225 11 22 77 84 68 NA NA NA NA NA NA NA 5224 FUN_034224 440 263 481 992 1737 NA NA NA NA NA NA NA 5225 FUN_034229 1016 800 557 888 641 NA NA NA NA NA NA NA 5226 FUN_034228 82 0 63 173 1014 NA NA NA NA NA NA NA 5227 FUN_006480 938 198 185 442 204 ptg000001l:13025902-13035473 P14381 1.85e-40 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 5228 FUN_006480 938 198 185 442 204 ptg000001l:13025902-13035473 P14381 1.85e-40 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 5229 FUN_006481 34 137 54 162 71 NA NA NA NA NA NA NA 5230 FUN_006488 48 156 82 155 209 NA NA NA NA NA NA NA 5231 FUN_014469 0 0 0 11 0 NA NA NA NA NA NA NA 5232 FUN_014468 63 55 51 116 109 NA NA NA NA NA NA NA 5233 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 0 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5234 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 6.47e-174 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5235 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 2.05e-106 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5236 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 7.12e-92 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5237 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 5.04e-68 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5238 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 6.89e-52 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5239 FUN_014463 1752 1047 1048 1374 1644 ptg000009l:397367-404425 O75976 1.38e-49 Carboxypeptidase D (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180) Homo sapiens (Human) peptide metabolic process [GO:0006518]; protein processing [GO:0016485] GO:0004181; GO:0004185; GO:0005615; GO:0005886; GO:0006518; GO:0008270; GO:0016020; GO:0016485; GO:0070062 5240 FUN_014462 1840 1508 1412 1964 2105 NA NA NA NA NA NA NA 5241 FUN_014461 2051 1758 1293 1421 1274 NA NA NA NA NA NA NA 5242 FUN_014467 690 1327 277 527 180 NA NA NA NA NA NA NA 5243 FUN_014466 881 1130 386 777 611 NA NA NA NA NA NA NA 5244 FUN_014465 8 13 14 30 0 NA NA NA NA NA NA NA 5245 FUN_014464 30 36 38 116 150 NA NA NA NA NA NA NA 5246 FUN_011455 10 0 1 9 65 NA NA NA NA NA NA NA 5247 FUN_011454 0 0 15 0 73 NA NA NA NA NA NA NA 5248 FUN_011457 0 0 17 0 0 NA NA NA NA NA NA NA 5249 FUN_043176 5611 6607 4330 4878 3210 NA NA NA NA NA NA NA 5250 FUN_011450 3 57 12 5 4 NA NA NA NA NA NA NA 5251 FUN_011453 1 5 10 1 22 NA NA NA NA NA NA NA 5252 FUN_000974 11 0 5 8 11 NA NA NA NA NA NA NA 5253 FUN_000975 0 0 0 0 10 NA NA NA NA NA NA NA 5254 FUN_000976 575 54 537 222 268 NA NA NA NA NA NA NA 5255 FUN_000977 5639 3973 3046 5291 3492 ntLink_6:6648442-6666630 P00541 3.57e-31 Tyrosine-protein kinase transforming protein Fps (EC 2.7.10.2) Avian sarcoma virus (strain PRCII) NA GO:0004715; GO:0005524 5256 FUN_011459 0 0 19 3 71 NA NA NA NA NA NA NA 5257 FUN_000971 661 269 383 810 740 NA NA NA NA NA NA NA 5258 FUN_000972 2944 2748 1668 2555 2361 NA NA NA NA NA NA NA 5259 FUN_000973 309 263 191 331 265 ntLink_6:6622793-6625859 Q5PRB3 3.67e-25 PIH1 domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) axonemal dynein complex assembly [GO:0070286]; box C/D snoRNP assembly [GO:0000492]; rRNA processing [GO:0006364] GO:0000492; GO:0005737; GO:0006364; GO:0070286; GO:0097255; GO:1990904 5260 FUN_014799 3487 3033 1207 2976 2623 ptg000009l:3206941-3217167 A7RWP6 2.25e-34 Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005634; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0071540 5261 FUN_014799 3487 3033 1207 2976 2623 ptg000009l:3206941-3217167 A7RWP6 6.52e-30 Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003743; GO:0005634; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0071540 5262 FUN_014798 28049 30567 19418 33481 21965 ptg000009l:3197563-3201483 O00560 1.9e-37 Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of receptor internalization [GO:0002091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of exosomal secretion [GO:1903543]; positive regulation of extracellular exosome assembly [GO:1903553]; positive regulation of JNK cascade [GO:0046330]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of phosphorylation [GO:0042327]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; presynapse assembly [GO:0099054]; protein targeting to membrane [GO:0006612]; proteolysis [GO:0006508]; Ras protein signal transduction [GO:0007265]; regulation of mitotic cell cycle [GO:0007346]; substrate-dependent cell migration, cell extension [GO:0006930] GO:0000122; GO:0002091; GO:0004222; GO:0005109; GO:0005137; GO:0005546; GO:0005576; GO:0005615; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005789; GO:0005829; GO:0005856; GO:0005886; GO:0005895; GO:0005912; GO:0005925; GO:0006508; GO:0006612; GO:0006930; GO:0007265; GO:0007268; GO:0007346; GO:0008022; GO:0008093; GO:0008284; GO:0010718; GO:0010862; GO:0014069; GO:0016020; GO:0019838; GO:0030036; GO:0030307; GO:0030335; GO:0030511; GO:0031965; GO:0032435; GO:0035255; GO:0035556; GO:0035578; GO:0042043; GO:0042327; GO:0042470; GO:0042802; GO:0044877; GO:0045121; GO:0045545; GO:0046330; GO:0046875; GO:0046982; GO:0047485; GO:0050839; GO:0070062; GO:0072562; GO:0098793; GO:0099054; GO:1903543; GO:1903553; GO:1903561 5263 FUN_014791 494 355 53 242 186 NA NA NA NA NA NA NA 5264 FUN_014790 0 0 20 3 27 NA NA NA NA NA NA NA 5265 FUN_014793 1606 1675 759 1435 1363 NA NA NA NA NA NA NA 5266 FUN_013160 3872 2926 1968 2942 2781 NA NA NA NA NA NA NA 5267 FUN_007134 1630 347 252 1126 522 NA NA NA NA NA NA NA 5268 FUN_009704 129 232 594 1314 2194 NA NA NA NA NA NA NA 5269 FUN_009705 189 215 609 1907 2285 ptg000004l:10569818-10575052 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 5270 FUN_009705 189 215 609 1907 2285 ptg000004l:10569818-10575052 Q9NZJ4 3.8e-45 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 5271 FUN_009705 189 215 609 1907 2285 ptg000004l:10569818-10575052 Q9NZJ4 8.31e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 5272 FUN_009706 6 36 125 433 703 ptg000004l:10575275-10582609 Q9JLC8 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 5273 FUN_009706 6 36 125 433 703 ptg000004l:10575275-10582609 Q9JLC8 1.82e-50 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 5274 FUN_009706 6 36 125 433 703 ptg000004l:10575275-10582609 Q9JLC8 3.64e-48 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 5275 FUN_009706 6 36 125 433 703 ptg000004l:10575275-10582609 Q9JLC8 1.32e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 5276 FUN_009707 0 0 0 0 59 NA NA NA NA NA NA NA 5277 FUN_009702 0 6 0 0 7 ptg000004l:10555247-10558609 P18708 6.04e-33 Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; SNARE complex disassembly [GO:0035494] GO:0000149; GO:0001921; GO:0005524; GO:0005794; GO:0005829; GO:0005886; GO:0006813; GO:0006886; GO:0016887; GO:0017075; GO:0019901; GO:0030165; GO:0030496; GO:0035255; GO:0035494; GO:0042802; GO:0044877; GO:0045732; GO:0046872; GO:0140545 5278 FUN_009702 0 6 0 0 7 ptg000004l:10555247-10558609 P18708 5e-25 Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) intracellular protein transport [GO:0006886]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor recycling [GO:0001921]; potassium ion transport [GO:0006813]; SNARE complex disassembly [GO:0035494] GO:0000149; GO:0001921; GO:0005524; GO:0005794; GO:0005829; GO:0005886; GO:0006813; GO:0006886; GO:0016887; GO:0017075; GO:0019901; GO:0030165; GO:0030496; GO:0035255; GO:0035494; GO:0042802; GO:0044877; GO:0045732; GO:0046872; GO:0140545 5279 FUN_009708 7 123 216 322 164 NA NA NA NA NA NA NA 5280 FUN_009709 6 14 0 10 43 NA NA NA NA NA NA NA 5281 FUN_029603 44 6 13 25 22 NA NA NA NA NA NA NA 5282 FUN_029602 1656 309 316 572 800 ptg000023l:3630545-3632750 E7FAM5 1.04e-59 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5283 FUN_029600 1536 430 277 389 537 ptg000023l:3611583-3621946 E7FAM5 6.2e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5284 FUN_029600 1536 430 277 389 537 ptg000023l:3611583-3621946 E7FAM5 8.71e-51 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5285 FUN_029607 87 264 424 391 95 ptg000023l:3670854-3673056 E7FAM5 1.33e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5286 FUN_029605 1640 1024 581 995 197 ptg000023l:3656526-3658695 E7FAM5 5.76e-59 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5287 FUN_029604 402 569 444 554 640 ptg000023l:3640817-3642992 E7FAM5 1.15e-61 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5288 FUN_029609 178 136 79 139 91 ptg000023l:3698554-3703836 E7FAM5 3.41e-49 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5289 FUN_029608 20 0 49 72 69 ptg000023l:3694270-3696442 E7FAM5 2.51e-48 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5290 FUN_026536 2 0 5 0 7 NA NA NA NA NA NA NA 5291 FUN_026537 474 230 197 602 103 NA NA NA NA NA NA NA 5292 FUN_026538 1217 756 681 1338 764 ptg000020l:10251919-10263746 O70310 7.59e-23 Glycylpeptide N-tetradecanoyltransferase 1 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) (Peptide N-myristoyltransferase 1) Mus musculus (Mouse) cellular ketone metabolic process [GO:0042180]; in utero embryonic development [GO:0001701]; N-terminal peptidyl-glycine N-myristoylation [GO:0018008]; N-terminal protein myristoylation [GO:0006499] GO:0001701; GO:0004379; GO:0005737; GO:0005829; GO:0005886; GO:0006499; GO:0018008; GO:0018030; GO:0019107; GO:0019898; GO:0042180 5293 FUN_026539 13579 19881 14555 13156 17402 NA NA NA NA NA NA NA 5294 FUN_041856 0 6 1 0 2 NA NA NA NA NA NA NA 5295 FUN_042229 35 0 23 21 184 NA NA NA NA NA NA NA 5296 FUN_042221 0 0 4 0 17 NA NA NA NA NA NA NA 5297 FUN_042226 75 236 138 186 308 NA NA NA NA NA NA NA 5298 FUN_016107 875 1644 930 2983 2036 NA NA NA NA NA NA NA 5299 FUN_016105 1273 1561 856 1349 933 NA NA NA NA NA NA NA 5300 FUN_022227 0 13 15 0 0 NA NA NA NA NA NA NA 5301 FUN_042803 74 10 4 4 19 NA NA NA NA NA NA NA 5302 FUN_024975 2 0 0 0 8 NA NA NA NA NA NA NA 5303 FUN_024972 9 0 0 0 5 NA NA NA NA NA NA NA 5304 FUN_024973 0 0 0 0 7 NA NA NA NA NA NA NA 5305 FUN_025379 0 4 163 0 276 ptg000019l:2096852-2101100 A1L0Y2 2.24e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5306 FUN_025379 0 4 163 0 276 ptg000019l:2096852-2101100 A1L0Y2 2.24e-30 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5307 FUN_025379 0 4 163 0 276 ptg000019l:2096852-2101100 A1L0Y2 1.21e-23 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5308 FUN_025379 0 4 163 0 276 ptg000019l:2096852-2101100 A1L0Y2 1.21e-23 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5309 FUN_025379 0 4 163 0 276 ptg000019l:2096852-2101100 A1L0Y2 3.79e-22 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5310 FUN_025379 0 4 163 0 276 ptg000019l:2096852-2101100 A1L0Y2 3.79e-22 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5311 FUN_025378 0 4 834 0 631 NA NA NA NA NA NA NA 5312 FUN_025377 0 0 9 0 28 NA NA NA NA NA NA NA 5313 FUN_025376 0 0 633 0 690 NA NA NA NA NA NA NA 5314 FUN_025375 0 103 93 0 112 NA NA NA NA NA NA NA 5315 FUN_025374 2 0 367 3 195 NA NA NA NA NA NA NA 5316 FUN_025373 2024 1328 1081 1732 1387 ptg000019l:2002726-2020960 A1L0Y2 4.36e-49 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5317 FUN_025373 2024 1328 1081 1732 1387 ptg000019l:2002726-2020960 A1L0Y2 3.75e-37 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5318 FUN_025373 2024 1328 1081 1732 1387 ptg000019l:2002726-2020960 A1L0Y2 4.47e-36 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5319 FUN_025373 2024 1328 1081 1732 1387 ptg000019l:2002726-2020960 A1L0Y2 5.48e-36 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5320 FUN_025373 2024 1328 1081 1732 1387 ptg000019l:2002726-2020960 A1L0Y2 3.81e-24 Neuralized-like protein 4 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737; GO:0005814 5321 FUN_025372 3864 2023 2292 2924 2486 NA NA NA NA NA NA NA 5322 FUN_025371 1059 1096 423 379 348 NA NA NA NA NA NA NA 5323 FUN_025370 413 292 337 226 330 NA NA NA NA NA NA NA 5324 FUN_024398 1297 861 316 690 621 ptg000018l:5797313-5821265 Q5RG45 2.76e-68 Centrosomal protein of 135 kDa (Cep135) Danio rerio (Zebrafish) (Brachydanio rerio) centriole replication [GO:0007099] GO:0005737; GO:0005813; GO:0005814; GO:0007099 5325 FUN_024399 2576 2549 1185 1967 1561 NA NA NA NA NA NA NA 5326 FUN_024392 7085 5502 2293 5613 2862 NA NA NA NA NA NA NA 5327 FUN_024393 0 42 102 375 407 NA NA NA NA NA NA NA 5328 FUN_024390 893 558 513 630 573 ptg000018l:5684500-5692822 Q7Z3G6 1.62e-43 Prickle-like protein 2 Homo sapiens (Human) Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0005737; GO:0008270; GO:0031965; GO:0060071 5329 FUN_024390 893 558 513 630 573 ptg000018l:5684500-5692822 Q7Z3G6 2.9e-22 Prickle-like protein 2 Homo sapiens (Human) Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0005737; GO:0008270; GO:0031965; GO:0060071 5330 FUN_024391 2453 3551 1403 2684 2199 ptg000018l:5708831-5721160 A1Z6W3 9.83e-28 Protein prickle (Protein spiny legs) Drosophila melanogaster (Fruit fly) anterior/posterior axis specification [GO:0009948]; axonal transport [GO:0098930]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; establishment of protein localization [GO:0045184]; establishment of tissue polarity [GO:0007164]; establishment or maintenance of cell polarity [GO:0007163]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; maintenance of protein location [GO:0045185]; morphogenesis of a polarized epithelium [GO:0001738]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669] GO:0001736; GO:0001737; GO:0001738; GO:0005737; GO:0005829; GO:0005886; GO:0007163; GO:0007164; GO:0008270; GO:0009948; GO:0016318; GO:0030424; GO:0030951; GO:0042067; GO:0045184; GO:0045185; GO:0045773; GO:0098930; GO:1902669 5331 FUN_024396 5 44 34 21 30 ptg000018l:5786035-5786599 P57101 1.81e-26 Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0046983 5332 FUN_024397 1812 925 1097 1344 1839 NA NA NA NA NA NA NA 5333 FUN_024394 610 397 435 569 351 ptg000018l:5749648-5760090 Q9UMR3 1.17e-29 T-box transcription factor TBX20 (T-box protein 20) Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; atrial septum morphogenesis [GO:0060413]; atrioventricular canal development [GO:0036302]; atrioventricular valve development [GO:0003171]; blood circulation [GO:0008015]; branching involved in blood vessel morphogenesis [GO:0001569]; cardiac chamber formation [GO:0003207]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac right ventricle morphogenesis [GO:0003215]; cardiac septum development [GO:0003279]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube elongation [GO:0036306]; embryonic heart tube morphogenesis [GO:0003143]; endocardial cushion formation [GO:0003272]; endocardial cushion morphogenesis [GO:0003203]; endoderm formation [GO:0001706]; foramen ovale closure [GO:0035922]; heart looping [GO:0001947]; lateral mesoderm formation [GO:0048370]; mesenchymal cell development [GO:0014031]; motor neuron migration [GO:0097475]; muscle contraction [GO:0006936]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transcription by RNA polymerase II [GO:0000122]; outflow tract septum morphogenesis [GO:0003148]; pericardium morphogenesis [GO:0003344]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; pulmonary valve formation [GO:0003193]; pulmonary vein morphogenesis [GO:0060577]; regulation of transcription by RNA polymerase II [GO:0006357]; tricuspid valve development [GO:0003175]; vasculogenesis [GO:0001570]; visceral motor neuron differentiation [GO:0021524] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001569; GO:0001570; GO:0001706; GO:0001708; GO:0001947; GO:0003143; GO:0003148; GO:0003171; GO:0003175; GO:0003180; GO:0003193; GO:0003203; GO:0003207; GO:0003215; GO:0003272; GO:0003279; GO:0003344; GO:0005634; GO:0005737; GO:0006357; GO:0006936; GO:0008015; GO:0008283; GO:0009953; GO:0010718; GO:0010991; GO:0014031; GO:0021524; GO:0030513; GO:0035922; GO:0036302; GO:0036306; GO:0045892; GO:0048370; GO:0055008; GO:0060045; GO:0060413; GO:0060577; GO:0061629; GO:0097475; GO:1990837 5334 FUN_024395 325 103 43 153 137 NA NA NA NA NA NA NA 5335 FUN_030048 1462 1328 826 1204 1074 NA NA NA NA NA NA NA 5336 FUN_019448 0 0 0 0 192 NA NA NA NA NA NA NA 5337 FUN_030045 231 108 23 112 43 NA NA NA NA NA NA NA 5338 FUN_019441 0 0 0 9 0 NA NA NA NA NA NA NA 5339 FUN_038218 5890 7088 2863 4392 2226 ptg000027l:4328341-4331152 Q08BA6 3.72e-73 RNA demethylase ALKBH5 (EC 1.14.11.53) (Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; oxidative single-stranded RNA demethylation [GO:0035553]; response to hypoxia [GO:0001666]; spermatogenesis [GO:0007283] GO:0001666; GO:0005634; GO:0006397; GO:0006406; GO:0007283; GO:0016607; GO:0016706; GO:0035515; GO:0035553; GO:0046872; GO:1990931 5340 FUN_038219 2278 1135 1019 3513 1785 ptg000027l:4336567-4372875 Q6IVV8 8.07e-46 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 5341 FUN_038216 1204 1030 979 870 1126 NA NA NA NA NA NA NA 5342 FUN_038217 7995 4567 3226 7978 6819 NA NA NA NA NA NA NA 5343 FUN_038214 729 307 205 524 344 NA NA NA NA NA NA NA 5344 FUN_038215 1444 1209 925 171 1182 NA NA NA NA NA NA NA 5345 FUN_038213 8206 5200 3926 4904 4225 NA NA NA NA NA NA NA 5346 FUN_038210 50 0 24 37 40 ptg000027l:4210648-4223506 Q7Z442 4.49e-47 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 5347 FUN_038211 43 0 13 0 51 NA NA NA NA NA NA NA 5348 FUN_016605 1854 807 1222 927 861 NA NA NA NA NA NA NA 5349 FUN_014627 9218 6519 4877 9685 7914 ptg000009l:1687931-1689358 Q9NEW6 1.17e-34 Probable splicing factor, arginine/serine-rich 3 (CeSF2) (CeSF2/ASF) Caenorhabditis elegans alternative mRNA splicing, via spliceosome [GO:0000380]; embryo development ending in birth or egg hatching [GO:0009792]; mRNA splice site selection [GO:0006376]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000380; GO:0000398; GO:0003723; GO:0006376; GO:0008380; GO:0009792; GO:0016607 5350 FUN_023387 0 0 2 0 13 NA NA NA NA NA NA NA 5351 FUN_024028 222 141 115 316 227 NA NA NA NA NA NA NA 5352 FUN_024029 341 146 212 500 371 ptg000018l:1479596-1490227 Q9C0G6 2.08e-23 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 5353 FUN_024029 341 146 212 500 371 ptg000018l:1479596-1490227 Q9C0G6 2.08e-23 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 5354 FUN_024025 10321 10658 6669 7825 6054 NA NA NA NA NA NA NA 5355 FUN_024026 5572 6420 4414 8133 6410 NA NA NA NA NA NA NA 5356 FUN_024027 79 7 58 145 63 NA NA NA NA NA NA NA 5357 FUN_024020 34950 15559 12152 35449 14522 NA NA NA NA NA NA NA 5358 FUN_024021 1810 1008 1151 1618 1142 ptg000018l:1336653-1370678 Q17RP2 4.22e-31 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 5359 FUN_024021 1810 1008 1151 1618 1142 ptg000018l:1336653-1370678 Q17RP2 4.22e-31 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 5360 FUN_024021 1810 1008 1151 1618 1142 ptg000018l:1336653-1370678 Q17RP2 4.22e-31 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 5361 FUN_024021 1810 1008 1151 1618 1142 ptg000018l:1336653-1370678 Q17RP2 4.22e-31 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 5362 FUN_024022 288 114 247 306 271 NA NA NA NA NA NA NA 5363 FUN_024023 80 45 69 114 126 NA NA NA NA NA NA NA 5364 FUN_023382 159 185 135 188 27 NA NA NA NA NA NA NA 5365 FUN_023383 48392 23599 20463 26273 16497 NA NA NA NA NA NA NA 5366 FUN_021610 748 733 747 1137 579 ptg000016l:2606971-2617978 Q8IUC8 1.96e-33 Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13) Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0016266; GO:0018242; GO:0018243; GO:0030246; GO:0046872 5367 FUN_021610 748 733 747 1137 579 ptg000016l:2606971-2617978 Q8IUC8 2.5e-22 Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13) Homo sapiens (Human) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0016266; GO:0018242; GO:0018243; GO:0030246; GO:0046872 5368 FUN_021612 489 833 747 494 433 ptg000016l:2633000-2640830 Q6GNV7 1.16e-22 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 5369 FUN_021613 18 9 11 2 27 NA NA NA NA NA NA NA 5370 FUN_027853 1532 1100 623 989 668 NA NA NA NA NA NA NA 5371 FUN_014628 2648 2110 1449 3379 3612 NA NA NA NA NA NA NA 5372 FUN_027618 117 84 52 55 39 NA NA NA NA NA NA NA 5373 FUN_027612 0 0 0 12 0 NA NA NA NA NA NA NA 5374 FUN_027610 14 0 0 55 239 NA NA NA NA NA NA NA 5375 FUN_031798 1032 1344 1097 2846 293 ptg000023l:25587562-25589212 Q66KV4 1.22e-26 Barrier-to-autointegration factor B Xenopus laevis (African clawed frog) negative regulation of protein ADP-ribosylation [GO:0010836]; response to oxidative stress [GO:0006979] GO:0000785; GO:0003677; GO:0005635; GO:0005737; GO:0006979; GO:0010836 5376 FUN_031790 892 280 571 337 844 ptg000023l:25479575-25496752 K7VCB9 5.57e-21 Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (Thz kinase) Zea mays (Maize) phosphorylation [GO:0016310]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine salvage [GO:0036172] GO:0000287; GO:0004417; GO:0005524; GO:0009228; GO:0009229; GO:0016310; GO:0036172 5377 FUN_031791 435 0 260 18 448 ptg000023l:25499605-25500821 K7VCB9 1.35e-22 Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (Thz kinase) Zea mays (Maize) phosphorylation [GO:0016310]; thiamine biosynthetic process [GO:0009228]; thiamine diphosphate biosynthetic process [GO:0009229]; thiamine salvage [GO:0036172] GO:0000287; GO:0004417; GO:0005524; GO:0009228; GO:0009229; GO:0016310; GO:0036172 5378 FUN_031792 318 281 13 519 40 NA NA NA NA NA NA NA 5379 FUN_031793 73 27 144 156 105 NA NA NA NA NA NA NA 5380 FUN_031794 41 34 5 41 2 NA NA NA NA NA NA NA 5381 FUN_031795 1116 758 875 1859 578 NA NA NA NA NA NA NA 5382 FUN_031796 13 26 0 45 0 NA NA NA NA NA NA NA 5383 FUN_031797 1370 1745 1385 4048 345 ptg000023l:25574649-25576286 Q66KV4 1.19e-26 Barrier-to-autointegration factor B Xenopus laevis (African clawed frog) negative regulation of protein ADP-ribosylation [GO:0010836]; response to oxidative stress [GO:0006979] GO:0000785; GO:0003677; GO:0005635; GO:0005737; GO:0006979; GO:0010836 5384 FUN_007993 3506 1621 1977 2457 1784 NA NA NA NA NA NA NA 5385 FUN_002740 7 0 0 0 6 NA NA NA NA NA NA NA 5386 FUN_007991 12 0 0 23 14 NA NA NA NA NA NA NA 5387 FUN_036070 245 242 57 270 120 NA NA NA NA NA NA NA 5388 FUN_036071 29 39 0 21 10 NA NA NA NA NA NA NA 5389 FUN_036072 155 304 179 142 294 NA NA NA NA NA NA NA 5390 FUN_036073 1047 1555 495 1362 745 ptg000025l:15138980-15150822 Q9NRG7 1.67e-31 Epimerase family protein SDR39U1 (EC 1.1.1.-) (Short-chain dehydrogenase/reductase family 39U member 1) Homo sapiens (Human) NA GO:0005634; GO:0016491 5391 FUN_036074 1465 1190 903 1774 1505 NA NA NA NA NA NA NA 5392 FUN_036075 3348 2431 2225 2595 1343 NA NA NA NA NA NA NA 5393 FUN_036076 2005 1560 1567 1785 848 NA NA NA NA NA NA NA 5394 FUN_036077 9821 4071 3870 3839 2757 NA NA NA NA NA NA NA 5395 FUN_036078 84 2 134 40 112 NA NA NA NA NA NA NA 5396 FUN_007997 726 200 293 560 409 NA NA NA NA NA NA NA 5397 FUN_007996 0 0 0 4 7 NA NA NA NA NA NA NA 5398 FUN_037301 0 0 59 0 0 NA NA NA NA NA NA NA 5399 FUN_037303 77 132 105 117 51 NA NA NA NA NA NA NA 5400 FUN_037302 1980 1282 1430 2454 1722 ptg000026l:8456908-8482672 Q9NW08 1.75e-22 DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B) Homo sapiens (Human) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728] GO:0003677; GO:0003899; GO:0005654; GO:0005666; GO:0005829; GO:0006351; GO:0032549; GO:0032728; GO:0045087; GO:0045089; GO:0046872; GO:0051607 5401 FUN_037305 962 658 740 1418 503 NA NA NA NA NA NA NA 5402 FUN_037304 0 31 20 0 0 NA NA NA NA NA NA NA 5403 FUN_037307 2936 3183 2374 2033 1248 ptg000026l:8529917-8532659 P40946 3.04e-34 ADP-ribosylation factor 6 (ARF6) (ADP ribosylation factor at 51F) (ADP-ribosylation factor 3) Drosophila melanogaster (Fruit fly) actin cytoskeleton organization [GO:0030036]; behavioral response to ethanol [GO:0048149]; compound eye morphogenesis [GO:0001745]; imaginal disc-derived wing morphogenesis [GO:0007476]; intracellular protein transport [GO:0006886]; male meiosis cytokinesis [GO:0007112]; myoblast fusion [GO:0007520]; neurotransmitter secretion [GO:0007269]; positive regulation of gene expression [GO:0010628]; response to alcohol [GO:0097305]; spermatogenesis [GO:0007283]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192] GO:0001745; GO:0003924; GO:0005525; GO:0005737; GO:0005769; GO:0005794; GO:0005829; GO:0005886; GO:0006886; GO:0007112; GO:0007269; GO:0007283; GO:0007476; GO:0007520; GO:0008047; GO:0010628; GO:0016192; GO:0030036; GO:0032154; GO:0048149; GO:0048488; GO:0055037; GO:0097305; GO:0098793 5404 FUN_037306 1933 1732 1253 1809 1491 NA NA NA NA NA NA NA 5405 FUN_037309 349 291 434 282 306 ptg000026l:8546242-8550747 Q8MIZ3 2.6e-31 m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) Sus scrofa (Pig) cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069] GO:0000290; GO:0000340; GO:0000932; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0036245; GO:0042802; GO:0043069; GO:0045292; GO:0050072; GO:0140932 5406 FUN_037309 349 291 434 282 306 ptg000026l:8546242-8550747 Q8MIZ3 8.36e-21 m7GpppX diphosphatase (EC 3.6.1.59) (DCS-1) (Decapping scavenger enzyme) (Hint-related 7meGMP-directed hydrolase) (Histidine triad nucleotide-binding protein 5) (Histidine triad protein member 5) (HINT-5) (Scavenger mRNA-decapping enzyme DcpS) Sus scrofa (Pig) cellular response to menadione [GO:0036245]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA cis splicing, via spliceosome [GO:0045292]; negative regulation of programmed cell death [GO:0043069] GO:0000290; GO:0000340; GO:0000932; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0036245; GO:0042802; GO:0043069; GO:0045292; GO:0050072; GO:0140932 5407 FUN_037308 11286 9643 7476 6703 4331 ptg000026l:8540346-8544351 P26990 3.84e-36 ADP-ribosylation factor 6 (EC 3.6.5.2) Gallus gallus (Chicken) cell differentiation [GO:0030154]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; erythrocyte apoptotic process [GO:1902217]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; negative regulation of protein localization to cell surface [GO:2000009]; nervous system development [GO:0007399]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of neuron projection development [GO:0010975]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; vesicle-mediated transport [GO:0016192] GO:0001726; GO:0001889; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0005938; GO:0006886; GO:0007399; GO:0010975; GO:0016192; GO:0019003; GO:0030139; GO:0030154; GO:0030838; GO:0030866; GO:0031527; GO:0031996; GO:0032154; GO:0032456; GO:0032587; GO:0034394; GO:0035020; GO:0036010; GO:0047485; GO:0050714; GO:0051489; GO:0051549; GO:0055038; GO:0060998; GO:0090162; GO:0090543; GO:0097178; GO:0097284; GO:0120183; GO:1902217; GO:1903078; GO:2000009 5408 FUN_007994 546 1022 1413 987 2074 ptg000002l:6963262-6969470 Q8BKG3 4.35e-46 Inactive tyrosine-protein kinase 7 (Protein chuzhoi) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) Mus musculus (Mouse) actin cytoskeleton reorganization [GO:0031532]; axis elongation [GO:0003401]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; convergent extension [GO:0060026]; coronary vasculature development [GO:0060976]; establishment of epithelial cell apical/basal polarity [GO:0045198]; establishment of planar polarity [GO:0001736]; heart development [GO:0007507]; kidney development [GO:0001822]; lung-associated mesenchyme development [GO:0060484]; neural tube closure [GO:0001843]; planar cell polarity pathway involved in neural tube closure [GO:0090179]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of neuron projection development [GO:0010976]; regulation of canonical Wnt signaling pathway [GO:0060828]; ventricular septum development [GO:0003281]; wound healing [GO:0042060] GO:0001736; GO:0001822; GO:0001843; GO:0003281; GO:0003401; GO:0005886; GO:0005911; GO:0007155; GO:0007507; GO:0010976; GO:0016020; GO:0016477; GO:0031532; GO:0042060; GO:0045198; GO:0050839; GO:0060026; GO:0060484; GO:0060828; GO:0060976; GO:0071300; GO:0090103; GO:0090179; GO:0090263 5409 FUN_006021 0 4 52 16 75 NA NA NA NA NA NA NA 5410 FUN_006022 21 0 0 0 0 NA NA NA NA NA NA NA 5411 FUN_006023 39 0 0 0 97 NA NA NA NA NA NA NA 5412 FUN_006026 0 0 35 0 48 NA NA NA NA NA NA NA 5413 FUN_006027 16 0 0 0 6 NA NA NA NA NA NA NA 5414 FUN_008365 348 126 396 329 849 ptg000002l:10785065-10791657 H9JW43 1.18e-24 Chitin deacetylase 8 (BmCDA8) (EC 3.5.1.41) (Chitin deacetylase 17) Bombyx mori (Silk moth) chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004099; GO:0005615; GO:0006032; GO:0008270 5415 FUN_043451 2513 4221 2009 2503 431 NA NA NA NA NA NA NA 5416 FUN_013262 7 0 11 20 34 ptg000008l:20364383-20366681 Q0V8L6 1.92e-108 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 5417 FUN_005425 0 7 0 0 0 NA NA NA NA NA NA NA 5418 FUN_016767 0 0 12 0 0 NA NA NA NA NA NA NA 5419 FUN_001550 459 726 1389 533 552 NA NA NA NA NA NA NA 5420 FUN_001552 1748 1205 761 1958 1940 NA NA NA NA NA NA NA 5421 FUN_041346 0 0 5 66 0 NA NA NA NA NA NA NA 5422 FUN_001559 140 131 108 361 238 ntLink_6:13741311-13743510 E7FAM5 3.7e-67 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 5423 FUN_001558 0 11 0 0 0 NA NA NA NA NA NA NA 5424 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 7.63e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5425 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 2.98e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5426 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 8.22e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5427 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 2.16e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5428 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 5.91e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5429 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 3.55e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5430 FUN_013267 14 9 20 2 0 ptg000008l:20451294-20456614 Q96AY4 1.09e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5431 FUN_004970 104 154 70 63 49 NA NA NA NA NA NA NA 5432 FUN_016608 5506 3422 2101 3653 2530 NA NA NA NA NA NA NA 5433 FUN_001089 108 42 68 65 17 NA NA NA NA NA NA NA 5434 FUN_001088 328 308 172 337 284 NA NA NA NA NA NA NA 5435 FUN_042137 3 0 2 0 33 NA NA NA NA NA NA NA 5436 FUN_001083 138 142 69 189 153 ntLink_6:8354366-8356797 P30549 1.23e-23 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Mus musculus (Mouse) intestine smooth muscle contraction [GO:0014827]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of ion transport [GO:0043270]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; regulation of uterine smooth muscle contraction [GO:0070472]; response to electrical stimulus [GO:0051602] GO:0004995; GO:0005886; GO:0014057; GO:0014827; GO:0016020; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0043270; GO:0051602; GO:0061827; GO:0070459; GO:0070472; GO:0070474; GO:0097225; GO:1902093 5437 FUN_001082 7714 8240 3500 5426 2807 NA NA NA NA NA NA NA 5438 FUN_001081 1557 1058 662 971 1091 NA NA NA NA NA NA NA 5439 FUN_001080 585 690 304 436 326 NA NA NA NA NA NA NA 5440 FUN_001087 4947 4164 2520 4129 2935 NA NA NA NA NA NA NA 5441 FUN_001086 6429 5568 3776 7056 5306 NA NA NA NA NA NA NA 5442 FUN_001085 525 381 303 430 557 NA NA NA NA NA NA NA 5443 FUN_001084 56 4 37 48 142 ntLink_6:8372055-8373153 F1R332 5.26e-22 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 5444 FUN_044163 0 3 11 10 17 NA NA NA NA NA NA NA 5445 FUN_033551 424 3 585 142 529 NA NA NA NA NA NA NA 5446 FUN_033552 3 0 9 0 10 NA NA NA NA NA NA NA 5447 FUN_033553 0 0 13 304 162 NA NA NA NA NA NA NA 5448 FUN_033554 2 0 6 261 73 NA NA NA NA NA NA NA 5449 FUN_033555 29 0 0 38 0 NA NA NA NA NA NA NA 5450 FUN_033556 0 9 0 18 154 NA NA NA NA NA NA NA 5451 FUN_033557 8 0 8 8 65 NA NA NA NA NA NA NA 5452 FUN_033558 0 0 3 0 9 ptg000023l:43241225-43244114 Q95SX7 3.3e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 5453 FUN_033558 0 0 3 0 9 ptg000023l:43241225-43244114 Q95SX7 3.3e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 5454 FUN_033558 0 0 3 0 9 ptg000023l:43241225-43244114 Q95SX7 3.3e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 5455 FUN_016762 6 9 19 32 44 ptg000011l:7156534-7163298 Q12542 4.12e-45 Laccase-2 (EC 1.10.3.2) (Benzenediol:oxygen oxidoreductase 2) (Diphenol oxidase 2) (Laccase II) (Urishiol oxidase 2) Agaricus bisporus (White button mushroom) lignin catabolic process [GO:0046274] GO:0005507; GO:0005576; GO:0046274; GO:0052716 5456 FUN_044162 10 20 75 70 261 NA NA NA NA NA NA NA 5457 FUN_030058 32 47 13 78 73 NA NA NA NA NA NA NA 5458 FUN_009504 0 0 12 15 4 NA NA NA NA NA NA NA 5459 FUN_007869 1588 2062 1606 633 703 NA NA NA NA NA NA NA 5460 FUN_009505 2 0 24 0 64 NA NA NA NA NA NA NA 5461 FUN_018188 298 217 198 383 225 NA NA NA NA NA NA NA 5462 FUN_018189 0 0 2 6 0 NA NA NA NA NA NA NA 5463 FUN_007863 366 277 141 446 393 NA NA NA NA NA NA NA 5464 FUN_007861 0 6 50 0 0 NA NA NA NA NA NA NA 5465 FUN_007860 3216 2872 2230 4803 3833 ptg000002l:5517458-5542188 Q6ZPV2 1.35e-24 Chromatin-remodeling ATPase INO80 (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) Mus musculus (Mouse) cell division [GO:0051301]; cellular response to ionizing radiation [GO:0071479]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; DNA repair [GO:0006281]; DNA-templated transcription [GO:0006351]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; mitotic sister chromatid segregation [GO:0000070]; positive regulation of cell growth [GO:0030307]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of transcription from RNA polymerase II promoter in response to stress [GO:0043618]; spindle assembly [GO:0051225]; telomere maintenance [GO:0000723]; UV-damage excision repair [GO:0070914] GO:0000070; GO:0000723; GO:0000724; GO:0003677; GO:0003779; GO:0005524; GO:0005634; GO:0005654; GO:0005819; GO:0005829; GO:0005874; GO:0006275; GO:0006281; GO:0006282; GO:0006302; GO:0006338; GO:0006351; GO:0008094; GO:0010571; GO:0016604; GO:0016887; GO:0030307; GO:0031011; GO:0033044; GO:0034644; GO:0042393; GO:0043014; GO:0043618; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0051225; GO:0051301; GO:0051726; GO:0060382; GO:0070914; GO:0071479; GO:0140658; GO:1904507; GO:2000045 5466 FUN_018180 721 427 542 773 455 NA NA NA NA NA NA NA 5467 FUN_007866 31041 24352 16308 26234 13512 ptg000002l:5592968-5594032 Q07352 1.31e-43 mRNA decay activator protein ZFP36L1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (TPA-induced sequence 11b) (Zinc finger protein 36, C3H1 type-like 1) (ZFP36-like 1) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; cellular response to cAMP [GO:0071320]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to raffinose [GO:0097403]; cellular response to salt stress [GO:0071472]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; chorio-allantoic fusion [GO:0060710]; ERK1 and ERK2 cascade [GO:0070371]; heart development [GO:0007507]; MAPK cascade [GO:0000165]; mesendoderm development [GO:0048382]; mRNA processing [GO:0006397]; mRNA transport [GO:0051028]; multicellular organism growth [GO:0035264]; negative regulation of erythrocyte differentiation [GO:0045647]; negative regulation of mitotic cell cycle phase transition [GO:1901991]; neural tube development [GO:0021915]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; nuclear-transcribed mRNA catabolic process, deadenylation-independent decay [GO:0031086]; p38MAPK cascade [GO:0038066]; phosphatidylinositol 3-kinase signaling [GO:0014065]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of intracellular mRNA localization [GO:1904582]; positive regulation of monocyte differentiation [GO:0045657]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; proepicardium development [GO:0003342]; protein kinase B signaling [GO:0043491]; regulation of B cell differentiation [GO:0045577]; regulation of gene expression [GO:0010468]; regulation of keratinocyte apoptotic process [GO:1902172]; regulation of keratinocyte differentiation [GO:0045616]; regulation of keratinocyte proliferation [GO:0010837]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of mRNA stability [GO:0043488]; regulation of myoblast differentiation [GO:0045661]; regulation of stem cell proliferation [GO:0072091]; response to wounding [GO:0009611]; spongiotrophoblast layer development [GO:0060712]; T cell differentiation in thymus [GO:0033077]; vasculogenesis [GO:0001570] GO:0000165; GO:0000288; GO:0000932; GO:0001570; GO:0003342; GO:0003677; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0006915; GO:0007507; GO:0008283; GO:0009611; GO:0010468; GO:0010837; GO:0014065; GO:0021915; GO:0031086; GO:0031440; GO:0032869; GO:0033077; GO:0035264; GO:0035925; GO:0038066; GO:0043488; GO:0043491; GO:0044344; GO:0045577; GO:0045600; GO:0045616; GO:0045647; GO:0045657; GO:0045661; GO:0046872; GO:0048382; GO:0051028; GO:0060710; GO:0060712; GO:0061158; GO:0070371; GO:0071320; GO:0071356; GO:0071364; GO:0071375; GO:0071385; GO:0071456; GO:0071472; GO:0071560; GO:0071889; GO:0072091; GO:0097403; GO:1900153; GO:1901991; GO:1902172; GO:1904582; GO:1990904 5468 FUN_007865 865 622 485 1548 1125 NA NA NA NA NA NA NA 5469 FUN_007740 0 48 0 0 0 NA NA NA NA NA NA NA 5470 FUN_018456 42 61 15 3 93 NA NA NA NA NA NA NA 5471 FUN_034020 1652 1066 865 1288 1174 NA NA NA NA NA NA NA 5472 FUN_034023 21594 19317 18175 24346 18899 NA NA NA NA NA NA NA 5473 FUN_034022 5455 4418 2703 3768 3286 ptg000024l:3805169-3818031 Q16960 2.65e-33 Dynein intermediate chain 3, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 5474 FUN_034022 5455 4418 2703 3768 3286 ptg000024l:3805169-3818031 Q16960 4.49e-25 Dynein intermediate chain 3, ciliary Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) NA GO:0005737; GO:0005874; GO:0005929; GO:0030286 5475 FUN_018453 159 1962 159 2025 1321 NA NA NA NA NA NA NA 5476 FUN_034027 0 0 0 0 22 NA NA NA NA NA NA NA 5477 FUN_018451 636 132 107 330 431 NA NA NA NA NA NA NA 5478 FUN_034029 1577 1412 726 1111 941 ptg000024l:3916352-3924493 Q99873 5.01e-28 Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4) Homo sapiens (Human) cardiac muscle tissue development [GO:0048738]; cell surface receptor signaling pathway [GO:0007166]; histone H4-R3 methylation [GO:0043985]; in utero embryonic development [GO:0001701]; negative regulation of JNK cascade [GO:0046329]; negative regulation of megakaryocyte differentiation [GO:0045653]; neuron projection development [GO:0031175]; peptidyl-arginine methylation [GO:0018216]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]; RNA splicing [GO:0008380]; viral protein processing [GO:0019082] GO:0001701; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006479; GO:0007166; GO:0008168; GO:0008170; GO:0008276; GO:0008284; GO:0008327; GO:0008380; GO:0016274; GO:0018216; GO:0019082; GO:0019899; GO:0031175; GO:0034709; GO:0035241; GO:0035242; GO:0042054; GO:0042802; GO:0043985; GO:0044020; GO:0045648; GO:0045652; GO:0045653; GO:0046329; GO:0046985; GO:0048273; GO:0048738; GO:0051260; GO:1900745; GO:1904047 5479 FUN_034029 1577 1412 726 1111 941 ptg000024l:3916352-3924493 Q99873 5.01e-28 Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4) Homo sapiens (Human) cardiac muscle tissue development [GO:0048738]; cell surface receptor signaling pathway [GO:0007166]; histone H4-R3 methylation [GO:0043985]; in utero embryonic development [GO:0001701]; negative regulation of JNK cascade [GO:0046329]; negative regulation of megakaryocyte differentiation [GO:0045653]; neuron projection development [GO:0031175]; peptidyl-arginine methylation [GO:0018216]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of erythrocyte differentiation [GO:0045648]; positive regulation of hemoglobin biosynthetic process [GO:0046985]; positive regulation of p38MAPK cascade [GO:1900745]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of megakaryocyte differentiation [GO:0045652]; RNA splicing [GO:0008380]; viral protein processing [GO:0019082] GO:0001701; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006479; GO:0007166; GO:0008168; GO:0008170; GO:0008276; GO:0008284; GO:0008327; GO:0008380; GO:0016274; GO:0018216; GO:0019082; GO:0019899; GO:0031175; GO:0034709; GO:0035241; GO:0035242; GO:0042054; GO:0042802; GO:0043985; GO:0044020; GO:0045648; GO:0045652; GO:0045653; GO:0046329; GO:0046985; GO:0048273; GO:0048738; GO:0051260; GO:1900745; GO:1904047 5480 FUN_034028 772 797 1027 820 315 NA NA NA NA NA NA NA 5481 FUN_018459 19 0 0 0 0 ptg000012l:9661955-9666269 C0H690 2.23e-27 Small cysteine-rich protein 1 (Amil-SCRiP1) (SCRiP1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 5482 FUN_011761 998 760 479 1009 783 NA NA NA NA NA NA NA 5483 FUN_000429 323 38 38 389 0 ntLink_6:2919874-2923826 P0C6B8 2.83e-23 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 5484 FUN_000286 102 64 289 124 79 ntLink_6:1067606-1069698 P12804 6.37e-33 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 5485 FUN_011769 6467 5428 4045 13787 10986 NA NA NA NA NA NA NA 5486 FUN_005671 0 0 0 0 9 NA NA NA NA NA NA NA 5487 FUN_000421 0 3 0 27 0 ntLink_6:2777819-2778850 A0A1D5NSM8 2.58e-21 NA NA NA NA 5488 FUN_000284 455 281 289 704 268 NA NA NA NA NA NA NA 5489 FUN_005673 0 0 3 0 8 NA NA NA NA NA NA NA 5490 FUN_000282 16 0 0 0 19 NA NA NA NA NA NA NA 5491 FUN_030672 799 531 356 299 392 ptg000023l:14582252-14583866 P55345 2.25e-128 Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2) Homo sapiens (Human) developmental cell growth [GO:0048588]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-arginine methylation [GO:0018216]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-templated transcription [GO:0045893]; protein methylation [GO:0006479]; regulation of androgen receptor signaling pathway [GO:0060765]; signal transduction [GO:0007165] GO:0003713; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006479; GO:0007165; GO:0008469; GO:0016274; GO:0018216; GO:0030331; GO:0032088; GO:0033142; GO:0035242; GO:0042054; GO:0042803; GO:0042974; GO:0042975; GO:0043065; GO:0044877; GO:0045892; GO:0045893; GO:0046966; GO:0048588; GO:0050681; GO:0060765; GO:0140592; GO:2000134 5492 FUN_031735 619 835 122 462 353 ptg000023l:24864312-24865023 Q5HZL9 5.75e-45 Haloacid dehalogenase-like hydrolase domain-containing protein 3 Xenopus laevis (African clawed frog) NA NA 5493 FUN_030673 2772 2662 1477 2257 1256 NA NA NA NA NA NA NA 5494 FUN_000280 70 188 160 22 47 NA NA NA NA NA NA NA 5495 FUN_007139 153 63 58 166 127 NA NA NA NA NA NA NA 5496 FUN_043379 1424 823 672 1046 1023 ptg000047l:7729761-7743704 Q6PFM9 1.93e-21 WD repeat-containing protein 48 (USP1-associated factor 1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of double-strand break repair via homologous recombination [GO:1905168] GO:0000724; GO:0003677; GO:0003690; GO:0003697; GO:0005634; GO:0005764; GO:0005770; GO:0006974; GO:0035800; GO:0043130; GO:1905168 5497 FUN_043378 14822 8314 6418 12109 8725 NA NA NA NA NA NA NA 5498 FUN_007131 59 0 3 49 48 NA NA NA NA NA NA NA 5499 FUN_043371 838 162 46 1182 210 ptg000047l:7676621-7678277 Q8VHQ9 6.13e-117 Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; intracellular signal transduction [GO:0035556]; negative regulation of cold-induced thermogenesis [GO:0120163]; response to cold [GO:0009409]; response to temperature stimulus [GO:0009266] GO:0005737; GO:0005759; GO:0005829; GO:0006631; GO:0006637; GO:0009266; GO:0009409; GO:0016290; GO:0035556; GO:0036042; GO:0047617; GO:0052816; GO:0102991; GO:0120163 5500 FUN_007132 0 0 0 0 10 NA NA NA NA NA NA NA 5501 FUN_043377 804 610 388 395 514 ptg000047l:7699559-7705331 A8WE67 3.79e-58 KIF-binding protein (KIF1-binding protein) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system projection neuron axonogenesis [GO:0021952]; efferent axon development in posterior lateral line nerve [GO:0048929]; enteric nervous system development [GO:0048484]; microtubule cytoskeleton organization [GO:0000226]; mitochondrial transport [GO:0006839]; nervous system development [GO:0007399]; neuron projection maintenance [GO:1990535] GO:0000226; GO:0005739; GO:0005856; GO:0006839; GO:0007399; GO:0021952; GO:0048484; GO:0048929; GO:1990535 5502 FUN_043376 181 166 92 197 114 NA NA NA NA NA NA NA 5503 FUN_007137 276 306 159 104 426 NA NA NA NA NA NA NA 5504 FUN_043374 279 167 181 301 314 NA NA NA NA NA NA NA 5505 FUN_041209 62 152 27 132 135 NA NA NA NA NA NA NA 5506 FUN_013368 9744 11098 8717 10027 6444 NA NA NA NA NA NA NA 5507 FUN_041205 141 0 0 6 0 NA NA NA NA NA NA NA 5508 FUN_013364 296 285 324 499 325 ptg000008l:21687329-21690843 Q5ZIT5 3.49e-38 Ras-related protein Rab-10 (EC 3.6.5.2) Gallus gallus (Chicken) axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005789; GO:0005794; GO:0005802; GO:0005886; GO:0005929; GO:0006893; GO:0006904; GO:0007409; GO:0008021; GO:0009306; GO:0016192; GO:0016197; GO:0017157; GO:0019003; GO:0030670; GO:0030859; GO:0031489; GO:0032593; GO:0032869; GO:0043001; GO:0043231; GO:0045200; GO:0048471; GO:0055037; GO:0055038; GO:0071782; GO:0071786; GO:0072659; GO:0097051; GO:1903361 5509 FUN_013367 4864 3180 5524 4643 8969 NA NA NA NA NA NA NA 5510 FUN_013366 13843 11988 10105 15081 12416 NA NA NA NA NA NA NA 5511 FUN_041201 0 27 0 40 0 NA NA NA NA NA NA NA 5512 FUN_041200 10 11 0 0 0 NA NA NA NA NA NA NA 5513 FUN_013362 735 1126 536 698 297 ptg000008l:21680751-21683461 Q5F470 5.46e-29 Ras-related protein Rab-8A (EC 3.6.5.2) Gallus gallus (Chicken) axonogenesis [GO:0007409]; cilium assembly [GO:0060271]; endocytic recycling [GO:0032456]; Golgi organization [GO:0007030]; Golgi vesicle fusion to target membrane [GO:0048210]; neurotransmitter receptor transport to postsynaptic membrane [GO:0098969]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904] GO:0003924; GO:0005525; GO:0005768; GO:0005813; GO:0005886; GO:0006904; GO:0007030; GO:0007409; GO:0008021; GO:0009306; GO:0017157; GO:0019003; GO:0030140; GO:0031267; GO:0032456; GO:0043197; GO:0043231; GO:0048210; GO:0060271; GO:0072659; GO:0098969 5514 FUN_016768 18 12 0 62 11 ptg000011l:7254373-7257964 Q96AY4 3.19e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5515 FUN_016768 18 12 0 62 11 ptg000011l:7254373-7257964 Q96AY4 1.59e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5516 FUN_016768 18 12 0 62 11 ptg000011l:7254373-7257964 Q96AY4 7.19e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5517 FUN_016768 18 12 0 62 11 ptg000011l:7254373-7257964 Q96AY4 1.8e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5518 FUN_016768 18 12 0 62 11 ptg000011l:7254373-7257964 Q96AY4 2.17e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5519 FUN_016768 18 12 0 62 11 ptg000011l:7254373-7257964 Q96AY4 1.32e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5520 FUN_035048 988 661 483 717 1081 NA NA NA NA NA NA NA 5521 FUN_035049 894 518 395 541 577 NA NA NA NA NA NA NA 5522 FUN_035040 31 31 30 0 64 NA NA NA NA NA NA NA 5523 FUN_035041 174 256 64 120 94 NA NA NA NA NA NA NA 5524 FUN_035042 4 17 11 4 0 ptg000025l:3195531-3199074 A6QNK1 2.43e-44 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Bos taurus (Bovine) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; myelination [GO:0042552]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0008146; GO:0042552; GO:0046486; GO:0050694 5525 FUN_035043 1592 490 523 773 568 NA NA NA NA NA NA NA 5526 FUN_035044 526 434 357 529 415 NA NA NA NA NA NA NA 5527 FUN_035045 703 1893 493 428 223 NA NA NA NA NA NA NA 5528 FUN_035046 993 145 266 863 783 NA NA NA NA NA NA NA 5529 FUN_035047 368 144 125 318 176 ptg000025l:3252255-3260342 Q98925 1.66e-22 Interferon regulatory factor 2 (IRF-2) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0006357 5530 FUN_003937 2134 1397 1026 1885 818 NA NA NA NA NA NA NA 5531 FUN_003936 1240 1536 1384 1587 678 NA NA NA NA NA NA NA 5532 FUN_003930 1240 356 420 1052 915 NA NA NA NA NA NA NA 5533 FUN_003933 277 89 152 297 163 NA NA NA NA NA NA NA 5534 FUN_036530 0 3 0 2 36 NA NA NA NA NA NA NA 5535 FUN_003939 3 0 25 0 0 NA NA NA NA NA NA NA 5536 FUN_036534 2 0 0 0 7 NA NA NA NA NA NA NA 5537 FUN_036536 0 24 30 6 0 NA NA NA NA NA NA NA 5538 FUN_002047 0 0 0 53 120 NA NA NA NA NA NA NA 5539 FUN_002040 0 21 11 16 0 NA NA NA NA NA NA NA 5540 FUN_040550 1245 1165 1097 1461 1683 NA NA NA NA NA NA NA 5541 FUN_040551 44 0 0 56 70 NA NA NA NA NA NA NA 5542 FUN_040557 0 0 22 0 0 NA NA NA NA NA NA NA 5543 FUN_028300 1265 726 569 1096 990 ptg000021l:18043140-18044646 Q80Z96 2.29e-131 Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1) Mus musculus (Mouse) pigmentation [GO:0043473] GO:0005886; GO:0016020; GO:0016328; GO:0043473 5544 FUN_042074 0 65 0 0 0 NA NA NA NA NA NA NA 5545 FUN_010186 240 135 125 278 0 NA NA NA NA NA NA NA 5546 FUN_010180 0 0 0 0 22 NA NA NA NA NA NA NA 5547 FUN_010182 0 0 30 0 3 NA NA NA NA NA NA NA 5548 FUN_012973 2646 1846 1296 2448 1815 NA NA NA NA NA NA NA 5549 FUN_012972 248 288 227 154 90 NA NA NA NA NA NA NA 5550 FUN_012971 455 442 274 160 82 NA NA NA NA NA NA NA 5551 FUN_012970 98402 95794 46813 78719 19890 ptg000008l:17974313-17976820 A1Z6E0 7.67e-96 Protein gustavus Drosophila melanogaster (Fruit fly) cuticle pattern formation [GO:0035017]; dorsal appendage formation [GO:0046843]; germ cell development [GO:0007281]; intracellular signal transduction [GO:0035556]; oocyte anterior/posterior axis specification [GO:0007314]; pole cell migration [GO:0007280]; pole plasm assembly [GO:0007315]; positive regulation of protein catabolic process [GO:0045732]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein localization [GO:0008104]; wing disc morphogenesis [GO:0007472] GO:0005634; GO:0005737; GO:0005938; GO:0007280; GO:0007281; GO:0007314; GO:0007315; GO:0007472; GO:0008104; GO:0019005; GO:0031466; GO:0035017; GO:0035556; GO:0043161; GO:0045495; GO:0045732; GO:0046843; GO:0048471; GO:0070449 5552 FUN_010188 0 0 0 122 328 NA NA NA NA NA NA NA 5553 FUN_012975 37 8 0 49 0 NA NA NA NA NA NA NA 5554 FUN_012974 0 9 0 24 0 NA NA NA NA NA NA NA 5555 FUN_032096 1264 612 533 1208 951 NA NA NA NA NA NA NA 5556 FUN_032097 6263 4109 2584 4161 3616 NA NA NA NA NA NA NA 5557 FUN_032094 107 53 105 74 149 NA NA NA NA NA NA NA 5558 FUN_032095 1588 772 1181 1160 1071 NA NA NA NA NA NA NA 5559 FUN_032092 793 452 380 636 207 NA NA NA NA NA NA NA 5560 FUN_032093 3682 3583 1573 4831 2784 NA NA NA NA NA NA NA 5561 FUN_032090 366 1110 424 4156 19 NA NA NA NA NA NA NA 5562 FUN_032091 4166 2316 2137 3780 3497 ptg000023l:28742914-28769565 Q9NBX4 1.86e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 5563 FUN_032098 1247 1125 768 615 494 NA NA NA NA NA NA NA 5564 FUN_032099 1420 916 872 1387 1571 ptg000023l:28831736-28839329 P98192 6.34e-34 Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase) Mus musculus (Mouse) cerebellum morphogenesis [GO:0021587]; ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; membrane organization [GO:0061024]; myelination [GO:0042552]; paranodal junction assembly [GO:0030913]; phospholipid biosynthetic process [GO:0008654]; response to fatty acid [GO:0070542]; response to nutrient [GO:0007584]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; synapse assembly [GO:0007416] GO:0003824; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0006631; GO:0006650; GO:0007416; GO:0007584; GO:0008611; GO:0008654; GO:0009410; GO:0016287; GO:0021587; GO:0030913; GO:0031966; GO:0042552; GO:0042594; GO:0061024; GO:0070542 5565 FUN_009982 0 0 6 0 0 NA NA NA NA NA NA NA 5566 FUN_014802 19 0 20 23 1 NA NA NA NA NA NA NA 5567 FUN_032328 47 85 22 159 170 NA NA NA NA NA NA NA 5568 FUN_032329 0 0 7 2 29 NA NA NA NA NA NA NA 5569 FUN_032320 103 50 0 75 79 NA NA NA NA NA NA NA 5570 FUN_032321 7 0 0 0 0 NA NA NA NA NA NA NA 5571 FUN_032322 532 293 215 263 253 NA NA NA NA NA NA NA 5572 FUN_032323 284 172 153 336 289 NA NA NA NA NA NA NA 5573 FUN_032324 919 587 635 1017 493 NA NA NA NA NA NA NA 5574 FUN_032325 4221 5358 3588 3975 2196 NA NA NA NA NA NA NA 5575 FUN_032326 118 147 80 135 159 NA NA NA NA NA NA NA 5576 FUN_032327 107 108 20 166 191 NA NA NA NA NA NA NA 5577 FUN_008589 2466 1471 1437 3821 3069 NA NA NA NA NA NA NA 5578 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 2.34e-63 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5579 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 2.34e-63 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5580 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 2.91e-61 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5581 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 2.91e-61 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5582 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 1.08e-58 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5583 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 1.08e-58 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5584 FUN_008588 1166 996 329 611 279 ptg000002l:13126776-13192147 Q5U3U3 1.08e-58 Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) Danio rerio (Zebrafish) (Brachydanio rerio) fatty acid beta-oxidation [GO:0006635] GO:0004095; GO:0005739; GO:0005743; GO:0006635; GO:0008458 5585 FUN_008581 882 411 266 256 296 NA NA NA NA NA NA NA 5586 FUN_008580 2302 1638 1552 1790 1407 NA NA NA NA NA NA NA 5587 FUN_008583 4476 2382 2329 4528 4638 ptg000002l:13062181-13078178 Q99PV3 5e-30 Muskelin Rattus norvegicus (Rat) actin cytoskeleton reorganization [GO:0031532]; cell-matrix adhesion [GO:0007160]; regulation of cell shape [GO:0008360]; regulation of receptor internalization [GO:0002090] GO:0000151; GO:0001726; GO:0002090; GO:0005654; GO:0005737; GO:0005829; GO:0005938; GO:0007160; GO:0008360; GO:0031532; GO:0042802; GO:0042803; GO:0098794 5588 FUN_008582 19 43 6 29 47 NA NA NA NA NA NA NA 5589 FUN_008585 308 26 104 152 119 NA NA NA NA NA NA NA 5590 FUN_008584 795 696 390 689 647 NA NA NA NA NA NA NA 5591 FUN_011275 521 457 328 618 559 NA NA NA NA NA NA NA 5592 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 1.89e-44 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5593 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 2.98e-40 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5594 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 6.31e-36 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5595 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 4.61e-34 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5596 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 2.08e-31 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5597 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 5.79e-30 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5598 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 5.79e-30 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5599 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 1.78e-29 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5600 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 5.54e-29 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5601 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 5.54e-29 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5602 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 2.14e-25 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5603 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 4.29e-23 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5604 FUN_011277 31400 28427 15505 28382 25203 ptg000007l:8457417-8488848 P29742 4.9e-21 Clathrin heavy chain Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; compound eye development [GO:0048749]; compound eye retinal cell programmed cell death [GO:0046667]; dsRNA transport [GO:0033227]; endocytosis [GO:0006897]; extracellular matrix organization [GO:0030198]; intracellular protein transport [GO:0006886]; liquid clearance, open tracheal system [GO:0035002]; oocyte microtubule cytoskeleton polarization [GO:0008103]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of autophagy [GO:0010508]; positive regulation of endocytosis [GO:0045807]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of growth [GO:0040008]; regulation of tube length, open tracheal system [GO:0035159]; secretory granule organization [GO:0033363]; sperm individualization [GO:0007291]; synaptic vesicle exocytosis [GO:0016079] GO:0005198; GO:0005802; GO:0005886; GO:0005905; GO:0005938; GO:0006886; GO:0006897; GO:0006898; GO:0007268; GO:0007291; GO:0008103; GO:0010508; GO:0016079; GO:0030130; GO:0030132; GO:0030136; GO:0030141; GO:0030198; GO:0031410; GO:0031623; GO:0032051; GO:0033227; GO:0033363; GO:0035002; GO:0035159; GO:0040008; GO:0045334; GO:0045451; GO:0045807; GO:0046667; GO:0048471; GO:0048749; GO:0071439; GO:0098793 5605 FUN_011276 2334 1316 854 1510 1720 ptg000007l:8442481-8456290 Q1LY77 1.03e-32 Histone-lysine N-methyltransferase SETD1B-A (EC 2.1.1.354) (SET domain-containing protein 1B-A) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; hematopoietic progenitor cell differentiation [GO:0002244]; histone H3-K4 methylation [GO:0051568] GO:0002244; GO:0003723; GO:0005694; GO:0006325; GO:0016607; GO:0042800; GO:0048188; GO:0051568 5606 FUN_000358 0 0 12 0 0 NA NA NA NA NA NA NA 5607 FUN_011270 0 7 0 0 0 NA NA NA NA NA NA NA 5608 FUN_011273 6525 7297 4098 6676 4479 ptg000007l:8407200-8424625 Q76NU3 2.13e-26 T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) Dictyostelium discoideum (Social amoeba) protein folding [GO:0006457] GO:0005524; GO:0005832; GO:0006457; GO:0016887; GO:0045335; GO:0051082; GO:0140662 5609 FUN_011273 6525 7297 4098 6676 4479 ptg000007l:8407200-8424625 Q76NU3 2.13e-26 T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) Dictyostelium discoideum (Social amoeba) protein folding [GO:0006457] GO:0005524; GO:0005832; GO:0006457; GO:0016887; GO:0045335; GO:0051082; GO:0140662 5610 FUN_011272 0 0 0 0 40 NA NA NA NA NA NA NA 5611 FUN_041782 688 746 341 740 555 NA NA NA NA NA NA NA 5612 FUN_041783 19 100 17 14 33 NA NA NA NA NA NA NA 5613 FUN_041784 1591 888 549 970 572 ptg000035l:7462050-7468239 P51817 4.11e-33 cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1) Homo sapiens (Human) angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cell-substrate adhesion [GO:0031589]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epithelial tube morphogenesis [GO:0060562]; kidney morphogenesis [GO:0060993]; myeloid cell differentiation [GO:0030099]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of epithelial cell differentiation involved in kidney development [GO:2000696]; signal transduction [GO:0007165] GO:0001525; GO:0001935; GO:0004691; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005952; GO:0007155; GO:0007165; GO:0018105; GO:0030099; GO:0030155; GO:0030334; GO:0031589; GO:0043542; GO:0046777; GO:0060562; GO:0060993; GO:0106310; GO:2000696 5614 FUN_011278 91 108 42 122 50 NA NA NA NA NA NA NA 5615 FUN_000352 12822 11628 5838 11042 9259 NA NA NA NA NA NA NA 5616 FUN_000353 676 258 1813 1895 1450 NA NA NA NA NA NA NA 5617 FUN_019557 494 489 635 720 483 ptg000015l:3282862-3289471 Q7RTR2 2.16e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5618 FUN_019557 494 489 635 720 483 ptg000015l:3282862-3289471 Q7RTR2 1.1e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5619 FUN_019557 494 489 635 720 483 ptg000015l:3282862-3289471 Q7RTR2 7.57e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5620 FUN_019557 494 489 635 720 483 ptg000015l:3282862-3289471 Q7RTR2 2.77e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5621 FUN_019557 494 489 635 720 483 ptg000015l:3282862-3289471 Q7RTR2 6.18e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5622 FUN_019557 494 489 635 720 483 ptg000015l:3282862-3289471 Q7RTR2 2.31e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5623 FUN_035310 2757 2607 1092 2469 1560 NA NA NA NA NA NA NA 5624 FUN_031468 1093 930 736 778 1601 NA NA NA NA NA NA NA 5625 FUN_008633 7837 8465 3560 7674 2255 NA NA NA NA NA NA NA 5626 FUN_008632 1182 1181 949 2068 1646 ptg000002l:13801036-13813313 Q2M3M2 5.71e-23 Sodium/glucose cotransporter 4 (Na(+)/glucose cotransporter 4) (hSGLT4) (Solute carrier family 5 member 9) Homo sapiens (Human) hexose transmembrane transport [GO:0008645]; sodium ion transport [GO:0006814] GO:0005362; GO:0005412; GO:0005886; GO:0006814; GO:0008645; GO:0016020; GO:0070062 5627 FUN_008631 106 276 75 1204 316 NA NA NA NA NA NA NA 5628 FUN_008630 18 23 30 53 35 NA NA NA NA NA NA NA 5629 FUN_008637 673 181 277 1297 469 NA NA NA NA NA NA NA 5630 FUN_008636 445 736 787 1071 472 NA NA NA NA NA NA NA 5631 FUN_008635 232 215 200 174 248 NA NA NA NA NA NA NA 5632 FUN_008634 2725 1684 1132 1707 1493 NA NA NA NA NA NA NA 5633 FUN_008639 237 321 232 452 313 NA NA NA NA NA NA NA 5634 FUN_035311 325 147 243 640 774 ptg000025l:6276631-6320742 P34457 8.2e-29 Putative uncharacterized transposon-derived protein F54H12.3 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0015074 5635 FUN_029063 41 63 49 369 310 NA NA NA NA NA NA NA 5636 FUN_029062 86 59 50 232 187 NA NA NA NA NA NA NA 5637 FUN_029061 832 367 140 312 210 ptg000022l:7767913-7768864 Q02360 4.01e-22 Fork head domain-containing protein L1 Drosophila melanogaster (Fruit fly) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0010628; GO:0030154 5638 FUN_014983 16386 18205 10616 11026 6892 NA NA NA NA NA NA NA 5639 FUN_014984 1415 4366 733 2843 1065 NA NA NA NA NA NA NA 5640 FUN_014985 2999 3229 2017 1927 1029 NA NA NA NA NA NA NA 5641 FUN_014986 2974 2589 2329 2344 1796 ptg000009l:5009599-5012542 Q7TNY1 7.27e-46 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (BTB/POZ domain-containing protein TNFAIP1) (Tumor necrosis factor-induced protein 1) Rattus norvegicus (Rat) cell migration [GO:0016477]; immune response [GO:0006955]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of DNA replication [GO:0045740]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; stress fiber assembly [GO:0043149] GO:0004842; GO:0005634; GO:0005737; GO:0005768; GO:0006955; GO:0016477; GO:0016567; GO:0030332; GO:0031267; GO:0031463; GO:0035024; GO:0042802; GO:0043149; GO:0043161; GO:0045740; GO:0051260 5642 FUN_014986 2974 2589 2329 2344 1796 ptg000009l:5009599-5012542 Q7TNY1 3.56e-25 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (BTB/POZ domain-containing protein TNFAIP1) (Tumor necrosis factor-induced protein 1) Rattus norvegicus (Rat) cell migration [GO:0016477]; immune response [GO:0006955]; negative regulation of Rho protein signal transduction [GO:0035024]; positive regulation of DNA replication [GO:0045740]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; stress fiber assembly [GO:0043149] GO:0004842; GO:0005634; GO:0005737; GO:0005768; GO:0006955; GO:0016477; GO:0016567; GO:0030332; GO:0031267; GO:0031463; GO:0035024; GO:0042802; GO:0043149; GO:0043161; GO:0045740; GO:0051260 5643 FUN_014987 8459 7005 3354 6005 3875 ptg000009l:5013082-5020400 O55028 6.47e-27 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (EC 2.7.11.4) (Branched-chain alpha-ketoacid dehydrogenase kinase) (BCKD-kinase) (BCKDHKIN) Mus musculus (Mouse) branched-chain amino acid catabolic process [GO:0009083]; isoleucine catabolic process [GO:0006550]; leucine catabolic process [GO:0006552]; phosphorylation [GO:0016310]; protein phosphorylation [GO:0006468]; regulation of glucose metabolic process [GO:0010906]; spermatogenesis [GO:0007283]; valine catabolic process [GO:0006574] GO:0004672; GO:0004674; GO:0004740; GO:0005524; GO:0005739; GO:0005947; GO:0006468; GO:0006550; GO:0006552; GO:0006574; GO:0007283; GO:0009083; GO:0010906; GO:0016310; GO:0047323 5644 FUN_014988 1435 1179 899 1665 1279 NA NA NA NA NA NA NA 5645 FUN_014989 939 1097 704 1312 779 NA NA NA NA NA NA NA 5646 FUN_029069 147 208 374 323 286 ptg000022l:7858046-7860926 B8RJM0 8.22e-53 Uncharacterized skeletal organic matrix protein 3 (Uncharacterized SOMP-3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 5647 FUN_029069 147 208 374 323 286 ptg000022l:7858046-7860926 B8RJM0 8.9e-39 Uncharacterized skeletal organic matrix protein 3 (Uncharacterized SOMP-3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 5648 FUN_029068 137 84 68 57 132 NA NA NA NA NA NA NA 5649 FUN_033059 66 159 35 65 63 NA NA NA NA NA NA NA 5650 FUN_033058 20 0 0 0 41 NA NA NA NA NA NA NA 5651 FUN_033051 616 349 410 906 943 NA NA NA NA NA NA NA 5652 FUN_033050 18 0 0 0 0 NA NA NA NA NA NA NA 5653 FUN_033053 1601 386 823 1425 1020 NA NA NA NA NA NA NA 5654 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 3.85e-49 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5655 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 1.75e-47 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5656 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 2.32e-46 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5657 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 2.99e-46 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5658 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 4.46e-46 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5659 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 5.75e-46 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5660 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 6.16e-46 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5661 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 1.07e-45 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5662 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 1.11e-45 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5663 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 1.23e-45 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5664 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 7.78e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5665 FUN_033055 0 0 0 30 17 ptg000023l:39407372-39411498 Q9UGM3 2.27e-21 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5666 FUN_033057 73 17 27 18 261 NA NA NA NA NA NA NA 5667 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 2.72e-55 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5668 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 5.31e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5669 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 1.21e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5670 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 8.41e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5671 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 9.07e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5672 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 1.5e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5673 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 1.5e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5674 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 1.69e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5675 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 1.76e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5676 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 2.66e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5677 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 3.14e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5678 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 4.43e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5679 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 1.91e-25 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5680 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 2.93e-23 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5681 FUN_033056 69 96 25 78 66 ptg000023l:39440062-39455840 Q9UGM3 2.75e-22 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 5682 FUN_039016 35 0 33 0 0 NA NA NA NA NA NA NA 5683 FUN_039015 35 0 14 14 138 NA NA NA NA NA NA NA 5684 FUN_039014 0 0 0 0 10 NA NA NA NA NA NA NA 5685 FUN_039013 19 0 0 0 1 NA NA NA NA NA NA NA 5686 FUN_039012 3054 0 0 0 29 NA NA NA NA NA NA NA 5687 FUN_039011 591 3 3 0 6 NA NA NA NA NA NA NA 5688 FUN_039010 421 0 0 0 0 NA NA NA NA NA NA NA 5689 FUN_039018 0 32 0 0 0 NA NA NA NA NA NA NA 5690 FUN_043765 0 113 164 479 0 ptg000049l:889118-890402 O95071 1.18e-21 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016020; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 5691 FUN_042848 34687 32056 19232 26578 22236 ptg000047l:888790-894057 Q63413 3.96e-74 Spliceosome RNA helicase Ddx39b (EC 3.6.4.13) (56 kDa U2AF65-associated protein) (ATP-dependent RNA helicase p47) (DEAD box protein Uap56) Rattus norvegicus (Rat) liver development [GO:0001889]; mRNA export from nucleus [GO:0006406]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA damage checkpoint [GO:2000002]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-templated transcription, elongation [GO:0032786]; positive regulation of translation [GO:0045727]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; RNA secondary structure unwinding [GO:0010501]; RNA splicing [GO:0008380]; spliceosomal complex assembly [GO:0000245]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000245; GO:0000346; GO:0000398; GO:0001889; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005687; GO:0005688; GO:0005737; GO:0006406; GO:0008186; GO:0008380; GO:0010501; GO:0016363; GO:0016607; GO:0016887; GO:0017070; GO:0030621; GO:0032786; GO:0032991; GO:0042802; GO:0043008; GO:0044877; GO:0045727; GO:0046784; GO:0061051; GO:1904707; GO:2000002; GO:2000573 5692 FUN_042849 0 0 2 0 33 NA NA NA NA NA NA NA 5693 FUN_042842 1890 2227 945 807 908 NA NA NA NA NA NA NA 5694 FUN_016723 139 161 46 126 25 ptg000011l:6701690-6705174 P48630 4.75e-114 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 5695 FUN_042840 1453 645 686 744 912 NA NA NA NA NA NA NA 5696 FUN_042841 66125 70596 26158 42185 31653 ptg000047l:780413-784409 O57592 1.72e-24 60S ribosomal protein L7a (Surfeit locus protein 3) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) ribosome biogenesis [GO:0042254] GO:0005737; GO:0005840; GO:0042254; GO:1990904 5697 FUN_042846 996 985 316 506 380 NA NA NA NA NA NA NA 5698 FUN_042847 629 340 309 698 320 ptg000047l:839731-887697 Q99315 1.61e-67 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 5699 FUN_042844 2814 2645 1665 2032 1277 NA NA NA NA NA NA NA 5700 FUN_016725 4270 2154 1266 1876 1545 ptg000011l:6713618-6719115 Q5FWL3 1.62e-132 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Xenopus laevis (African clawed frog) extrinsic apoptotic signaling pathway [GO:0097191]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0046872; GO:0061630; GO:0097191 5701 FUN_035314 0 32 37 19 13 NA NA NA NA NA NA NA 5702 FUN_010603 613 412 249 373 549 NA NA NA NA NA NA NA 5703 FUN_010602 202 136 94 271 375 NA NA NA NA NA NA NA 5704 FUN_010601 241 74 83 169 140 NA NA NA NA NA NA NA 5705 FUN_010600 640 662 358 775 802 ptg000007l:586351-588401 Q8R1Q3 7.11e-36 Angiopoietin-related protein 7 (Angiopoietin-like protein 7) Mus musculus (Mouse) negative regulation of vasculature development involved in avascular cornea development in camera-type eye [GO:1901346]; regulation of extracellular matrix organization [GO:1903053] GO:0005102; GO:0005576; GO:0005615; GO:0042802; GO:0062023; GO:1901346; GO:1903053 5706 FUN_010607 485 410 278 123 63 NA NA NA NA NA NA NA 5707 FUN_010606 1779 1311 373 1552 1278 NA NA NA NA NA NA NA 5708 FUN_010605 1208 548 402 921 834 NA NA NA NA NA NA NA 5709 FUN_010604 238 144 103 127 376 NA NA NA NA NA NA NA 5710 FUN_010609 1784 1073 530 496 317 NA NA NA NA NA NA NA 5711 FUN_010608 0 0 2 18 0 NA NA NA NA NA NA NA 5712 FUN_012115 327 194 245 236 401 ptg000008l:5248105-5259971 Q95LU3 3.33e-64 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 5713 FUN_012115 327 194 245 236 401 ptg000008l:5248105-5259971 Q95LU3 4.27e-57 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 5714 FUN_012114 13 0 36 0 84 NA NA NA NA NA NA NA 5715 FUN_012117 875 754 503 1177 1060 ptg000008l:5269809-5273165 Q95LU3 1.01e-62 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 5716 FUN_012116 24 409 10 1667 560 ptg000008l:5263283-5267177 Q95LU3 2.6e-57 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 5717 FUN_012111 54 35 39 5 87 NA NA NA NA NA NA NA 5718 FUN_012110 3130 2153 1314 2188 1688 ptg000008l:5217901-5221521 Q7TP47 1.1e-68 Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Liver regeneration-related protein LRRG077) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) Rattus norvegicus (Rat) cellular response to type II interferon [GO:0071346]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of mRNA modification [GO:0090367]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of translation [GO:0017148]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of translation [GO:0045727]; RNA splicing [GO:0008380] GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0006397; GO:0007623; GO:0008143; GO:0008380; GO:0016020; GO:0017148; GO:0043025; GO:0045727; GO:0048027; GO:0070934; GO:0070937; GO:0071013; GO:0071204; GO:0071346; GO:0090367; GO:0097452; GO:0106002; GO:1900152; GO:1990635; GO:1990904; GO:2000767 5719 FUN_012113 476 695 240 452 343 NA NA NA NA NA NA NA 5720 FUN_012119 612 334 241 441 560 NA NA NA NA NA NA NA 5721 FUN_012118 854 426 370 617 1286 NA NA NA NA NA NA NA 5722 FUN_020818 0 0 0 9 0 NA NA NA NA NA NA NA 5723 FUN_020815 71 0 4 70 165 NA NA NA NA NA NA NA 5724 FUN_020814 5 22 3 12 16 NA NA NA NA NA NA NA 5725 FUN_020817 0 34 0 69 5 NA NA NA NA NA NA NA 5726 FUN_020811 7 9 15 2 12 NA NA NA NA NA NA NA 5727 FUN_020810 0 81 8 2 38 NA NA NA NA NA NA NA 5728 FUN_020813 166 0 0 37 32 NA NA NA NA NA NA NA 5729 FUN_020812 39 0 25 3 110 NA NA NA NA NA NA NA 5730 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 6.67e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5731 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 3.01e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5732 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 1.48e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5733 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 2.38e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5734 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 2.03e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5735 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 3.04e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5736 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 8.03e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5737 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 4.86e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5738 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 4.86e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5739 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 8.37e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5740 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 2.29e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5741 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 3.92e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5742 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 2.18e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5743 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 9.91e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5744 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 2.12e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5745 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 2.64e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5746 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 3.7e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5747 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 9.4e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5748 FUN_038825 188 89 85 0 90 ptg000027l:11773024-11777388 Q96AY4 7.5e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 5749 FUN_038824 37 0 18 0 0 NA NA NA NA NA NA NA 5750 FUN_038821 42 0 24 20 0 NA NA NA NA NA NA NA 5751 FUN_027488 8 0 0 0 0 NA NA NA NA NA NA NA 5752 FUN_027895 6 3 0 11 0 NA NA NA NA NA NA NA 5753 FUN_027890 42 20 58 4 4 NA NA NA NA NA NA NA 5754 FUN_027891 378 245 54 334 99 NA NA NA NA NA NA NA 5755 FUN_027893 13 0 0 0 0 NA NA NA NA NA NA NA 5756 FUN_027898 33 37 18 30 65 NA NA NA NA NA NA NA 5757 FUN_027899 1087 546 839 535 726 NA NA NA NA NA NA NA 5758 FUN_014618 2692 2468 1538 2172 1936 ptg000009l:1613145-1617310 O88637 8.24e-124 Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase) Rattus norvegicus (Rat) phosphatidylethanolamine biosynthetic process [GO:0006646] GO:0004306; GO:0005737; GO:0006646 5759 FUN_014619 613 852 500 339 277 NA NA NA NA NA NA NA 5760 FUN_013648 124 314 143 136 142 ptg000008l:25022264-25024108 Q8K4H1 1.18e-65 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 5761 FUN_013649 301 160 309 80 241 ptg000008l:25026404-25028717 Q8K4H1 1.95e-67 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 5762 FUN_023393 2484 2173 1147 2314 1893 ptg000017l:7074965-7084794 O17438 1.59e-44 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) Strongylocentrotus purpuratus (Purple sea urchin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003724; GO:0005524; GO:0005634; GO:0006397; GO:0008380; GO:0016887 5763 FUN_023393 2484 2173 1147 2314 1893 ptg000017l:7074965-7084794 O17438 1.07e-39 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) Strongylocentrotus purpuratus (Purple sea urchin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003724; GO:0005524; GO:0005634; GO:0006397; GO:0008380; GO:0016887 5764 FUN_023393 2484 2173 1147 2314 1893 ptg000017l:7074965-7084794 O17438 3.47e-37 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) Strongylocentrotus purpuratus (Purple sea urchin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003724; GO:0005524; GO:0005634; GO:0006397; GO:0008380; GO:0016887 5765 FUN_023393 2484 2173 1147 2314 1893 ptg000017l:7074965-7084794 O17438 2.17e-26 Putative pre-mRNA-splicing factor ATP-dependent RNA helicase PRP1 (EC 3.6.4.13) Strongylocentrotus purpuratus (Purple sea urchin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003724; GO:0005524; GO:0005634; GO:0006397; GO:0008380; GO:0016887 5766 FUN_013643 471 106 242 263 326 NA NA NA NA NA NA NA 5767 FUN_013640 1938 1734 862 1438 832 NA NA NA NA NA NA NA 5768 FUN_013641 1249 523 578 657 598 NA NA NA NA NA NA NA 5769 FUN_014614 3158 3021 1877 2216 1511 NA NA NA NA NA NA NA 5770 FUN_023396 5660 4242 2709 6415 4640 NA NA NA NA NA NA NA 5771 FUN_014617 1132 263 247 1142 711 ptg000009l:1596736-1606320 Q96F81 7e-160 Protein dispatched homolog 1 Homo sapiens (Human) determination of left/right symmetry [GO:0007368]; diaphragm development [GO:0060539]; dorsal/ventral pattern formation [GO:0009953]; embryonic pattern specification [GO:0009880]; patched ligand maturation [GO:0007225]; peptide transport [GO:0015833]; protein homotrimerization [GO:0070207]; regulation of protein secretion [GO:0050708]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007225; GO:0007368; GO:0009880; GO:0009953; GO:0015833; GO:0016020; GO:0016323; GO:0022857; GO:0050708; GO:0055085; GO:0060539; GO:0070207; GO:1904680 5772 FUN_016232 197 93 174 356 169 NA NA NA NA NA NA NA 5773 FUN_004108 523 834 816 618 1306 ntLink_8:19344754-19346662 Q5ZL21 6.16e-69 Cyanocobalamin reductase / alkylcobalamin dealkylase (Alkylcobalamin:glutathione S-alkyltransferase) (EC 2.5.1.151) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) (EC 1.16.1.6) (Methylmalonic aciduria and homocystinuria type C protein) (MMACHC) Gallus gallus (Chicken) cobalamin metabolic process [GO:0009235]; demethylation [GO:0070988]; glutathione metabolic process [GO:0006749] GO:0005737; GO:0005829; GO:0006749; GO:0009235; GO:0016491; GO:0016740; GO:0031419; GO:0032451; GO:0033787; GO:0043295; GO:0070988; GO:0071949 5774 FUN_004611 2210 2263 1427 2992 1433 ntLink_8:24883251-24896741 A4Q9F6 3.92e-26 Tubulin polyglutamylase TTLL13 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 13) Mus musculus (Mouse) microtubule cytoskeleton organization [GO:0000226]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0046872; GO:0070740 5775 FUN_016233 845 42 740 1137 893 ptg000011l:662573-673475 Q70CQ2 3.11e-23 Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) Homo sapiens (Human) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016055; GO:0016579; GO:0071108; GO:0090263 5776 FUN_040308 115 90 77 254 204 NA NA NA NA NA NA NA 5777 FUN_043767 53 112 103 328 81 NA NA NA NA NA NA NA 5778 FUN_003192 0 0 2 0 12 NA NA NA NA NA NA NA 5779 FUN_003737 0 4 27 0 0 NA NA NA NA NA NA NA 5780 FUN_040302 643 524 229 254 317 NA NA NA NA NA NA NA 5781 FUN_003735 0 2 2 0 21 NA NA NA NA NA NA NA 5782 FUN_003734 0 0 0 10 0 NA NA NA NA NA NA NA 5783 FUN_004105 13 0 26 464 0 NA NA NA NA NA NA NA 5784 FUN_025944 421 174 203 364 187 ptg000020l:2270999-2275961 B8VIU6 2.67e-23 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5785 FUN_025945 63 23 11 84 170 ptg000020l:2286121-2289969 B8VIU6 1.96e-25 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5786 FUN_009517 36 15 94 24 21 NA NA NA NA NA NA NA 5787 FUN_009516 217 139 106 152 170 ptg000004l:7936523-7937381 Q8BL86 5.32e-85 Acyl-coenzyme A thioesterase MBLAC2 (Acyl-CoA thioesterase MBLAC2) (EC 3.1.2.2) (Beta-lactamase MBLAC2) (EC 3.5.2.6) (Metallo-beta-lactamase domain-containing protein 2) (Palmitoyl-coenzyme A thioesterase MBLAC2) Mus musculus (Mouse) fatty acid metabolic process [GO:0006631] GO:0005789; GO:0005886; GO:0006631; GO:0008800; GO:0016290; GO:0046872; GO:0102991 5788 FUN_025940 2 0 35 5 47 NA NA NA NA NA NA NA 5789 FUN_009510 12 0 0 11 2 NA NA NA NA NA NA NA 5790 FUN_009513 240 293 46 85 321 NA NA NA NA NA NA NA 5791 FUN_009512 195 47 13 115 70 ptg000004l:7892480-7896760 A0LNR4 7.79e-43 Putative hydro-lyase Sfum_3393 (EC 4.2.1.-) Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) NA GO:0016829 5792 FUN_003730 0 2 2 4 13 NA NA NA NA NA NA NA 5793 FUN_025949 53 0 30 32 89 ptg000020l:2335979-2341563 B8VIU6 3.07e-25 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5794 FUN_026765 0 0 0 0 19 NA NA NA NA NA NA NA 5795 FUN_026766 0 0 0 0 14 NA NA NA NA NA NA NA 5796 FUN_026761 0 0 0 13 8 NA NA NA NA NA NA NA 5797 FUN_026760 0 0 4 15 156 NA NA NA NA NA NA NA 5798 FUN_026763 25 0 1 115 0 NA NA NA NA NA NA NA 5799 FUN_026768 0 0 0 0 12 NA NA NA NA NA NA NA 5800 FUN_015569 0 0 3 4 25 NA NA NA NA NA NA NA 5801 FUN_022449 764 705 120 877 562 NA NA NA NA NA NA NA 5802 FUN_025498 82 0 0 0 49 NA NA NA NA NA NA NA 5803 FUN_025499 117 7 104 0 535 ptg000019l:3585098-3596979 Q61555 3.46e-24 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5804 FUN_025499 117 7 104 0 535 ptg000019l:3585098-3596979 Q61555 8.3e-21 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 5805 FUN_025497 68 0 0 0 59 NA NA NA NA NA NA NA 5806 FUN_015563 0 0 0 0 24 NA NA NA NA NA NA NA 5807 FUN_025495 0 0 0 0 22 NA NA NA NA NA NA NA 5808 FUN_022445 199 175 441 554 115 ptg000016l:9083127-9085109 Q29496 2.17e-70 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 5809 FUN_022445 199 175 441 554 115 ptg000016l:9083127-9085109 Q29496 1.83e-27 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 5810 FUN_036739 474 277 180 380 769 NA NA NA NA NA NA NA 5811 FUN_043754 0 0 0 12 0 NA NA NA NA NA NA NA 5812 FUN_027832 4524 1624 1610 2015 1406 NA NA NA NA NA NA NA 5813 FUN_027833 5 0 730 2 3 ptg000021l:11462402-11464241 R1CW23 1.81e-93 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 5814 FUN_027833 5 0 730 2 3 ptg000021l:11462402-11464241 R1CW23 1.95e-62 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 5815 FUN_027830 301 387 150 641 279 NA NA NA NA NA NA NA 5816 FUN_027831 1610 798 520 892 651 NA NA NA NA NA NA NA 5817 FUN_018012 1322 1272 475 1065 719 NA NA NA NA NA NA NA 5818 FUN_043752 0 0 0 0 26 NA NA NA NA NA NA NA 5819 FUN_018610 3 0 15 5 9 NA NA NA NA NA NA NA 5820 FUN_018010 8949 5727 5183 10805 6261 ptg000012l:3138432-3260010 Q8VDF3 3.22e-23 Death-associated protein kinase 2 (DAP kinase 2) (EC 2.7.11.1) (DAP-kinase-related protein 1) (DRP-1) Mus musculus (Mouse) anoikis [GO:0043276]; intracellular signal transduction [GO:0035556]; neutrophil migration [GO:1990266]; positive regulation of apoptotic process [GO:0043065]; positive regulation of eosinophil chemotaxis [GO:2000424]; positive regulation of neutrophil chemotaxis [GO:0090023]; protein phosphorylation [GO:0006468]; regulation of intrinsic apoptotic signaling pathway [GO:2001242] GO:0004674; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005794; GO:0006468; GO:0031410; GO:0034423; GO:0035556; GO:0042802; GO:0043065; GO:0043231; GO:0043276; GO:0090023; GO:0106310; GO:1990266; GO:2000424; GO:2001242 5821 FUN_018613 0 0 0 0 17 NA NA NA NA NA NA NA 5822 FUN_018011 3218 1730 1571 1038 757 NA NA NA NA NA NA NA 5823 FUN_018618 28 42 0 0 50 NA NA NA NA NA NA NA 5824 FUN_018619 0 0 7 30 2 NA NA NA NA NA NA NA 5825 FUN_025239 545 18 67 37 11 NA NA NA NA NA NA NA 5826 FUN_025232 7669 6526 4085 4508 3701 ptg000019l:257406-264111 P55070 1.16e-42 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) Lactarius deterrimus (False saffron milkcap) glycolytic process [GO:0006096] GO:0004365; GO:0005737; GO:0006096; GO:0051287 5827 FUN_025233 514 313 252 461 710 NA NA NA NA NA NA NA 5828 FUN_025230 0 0 0 380 34 NA NA NA NA NA NA NA 5829 FUN_025231 1068 649 382 880 866 ptg000019l:243220-255204 P21127 2.49e-25 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 5830 FUN_025231 1068 649 382 880 866 ptg000019l:243220-255204 P21127 2.49e-25 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 5831 FUN_025236 511 731 316 657 676 NA NA NA NA NA NA NA 5832 FUN_025237 16 16 0 10 26 NA NA NA NA NA NA NA 5833 FUN_025234 77 146 154 70 130 ptg000019l:275992-283824 P49916 2.85e-22 DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3) Homo sapiens (Human) base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298] GO:0000724; GO:0003677; GO:0003909; GO:0003910; GO:0005524; GO:0005634; GO:0005654; GO:0005739; GO:0006266; GO:0006273; GO:0006287; GO:0006288; GO:0006302; GO:0007005; GO:0007049; GO:0008270; GO:0043504; GO:0051301; GO:0070421; GO:0071897; GO:0090298; GO:0097681 5834 FUN_025235 633 408 68 650 607 NA NA NA NA NA NA NA 5835 FUN_024728 0 0 0 0 7 NA NA NA NA NA NA NA 5836 FUN_024727 62 14 54 48 136 NA NA NA NA NA NA NA 5837 FUN_024726 547 260 157 109 283 NA NA NA NA NA NA NA 5838 FUN_024725 131 123 156 475 246 ptg000018l:10318987-10322077 Q9UBS8 8.89e-108 E3 ubiquitin-protein ligase RNF14 (EC 2.3.2.31) (Androgen receptor-associated protein 54) (HFB30) (RING finger protein 14) (Triad2 protein) Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0006357; GO:0006511; GO:0007165; GO:0016567; GO:0019787; GO:0030521; GO:0031624; GO:0032436; GO:0045893; GO:0046872; GO:0050681; GO:0060765; GO:0061630 5839 FUN_024724 2349 1224 1427 1767 1907 NA NA NA NA NA NA NA 5840 FUN_024723 13 12 3 0 0 NA NA NA NA NA NA NA 5841 FUN_024722 328 194 220 362 287 ptg000018l:10285630-10286923 O15973 2e-21 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 5842 FUN_024720 20 0 9 0 0 ptg000018l:10272053-10276463 P13913 1.79e-25 Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 (Arylamine acetylase) (EC 2.3.1.5) Gallus gallus (Chicken) NA GO:0004060 5843 FUN_038009 886 812 483 778 1320 NA NA NA NA NA NA NA 5844 FUN_038008 967 659 440 564 603 NA NA NA NA NA NA NA 5845 FUN_038007 411 912 458 439 316 NA NA NA NA NA NA NA 5846 FUN_038006 153 428 271 256 258 NA NA NA NA NA NA NA 5847 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 6.76e-39 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5848 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 3.98e-38 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5849 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 3.4e-31 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5850 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 1.27e-30 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5851 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 1.27e-30 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5852 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 8.46e-28 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5853 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 1.05e-27 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5854 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 1.08e-27 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5855 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 7.81e-26 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5856 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 2.32e-25 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5857 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 2.44e-25 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5858 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 5.72e-25 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5859 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 2.29e-24 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5860 FUN_038005 4603 2354 2298 4311 4067 ptg000027l:1307839-1366256 Q8BW94 9.39e-23 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 5861 FUN_038004 1098 1469 1105 1702 852 ptg000027l:1295833-1304109 Q5XX13 5.27e-21 F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor) Homo sapiens (Human) NA GO:0005829 5862 FUN_038003 3553 4104 2593 2411 1975 ptg000027l:1291829-1294571 Q6DJF8 1.96e-24 Histone-arginine methyltransferase METTL23 (EC 2.1.1.319) (Methyltransferase-like protein 23) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-R17 methylation [GO:0034971] GO:0005634; GO:0005737; GO:0006325; GO:0034971; GO:0035242; GO:0035642 5863 FUN_038002 1064 1212 920 808 642 NA NA NA NA NA NA NA 5864 FUN_038001 17858 57070 23918 26907 15970 NA NA NA NA NA NA NA 5865 FUN_038000 1261 1525 843 1897 1152 NA NA NA NA NA NA NA 5866 FUN_021802 0 0 0 0 24 NA NA NA NA NA NA NA 5867 FUN_023012 1958 992 1203 1833 2304 NA NA NA NA NA NA NA 5868 FUN_026127 134 368 252 344 86 ptg000020l:4862336-4904653 O43422 4.76e-64 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 5869 FUN_026127 134 368 252 344 86 ptg000020l:4862336-4904653 O43422 4.76e-64 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 5870 FUN_028041 2257 1224 402 2112 1113 NA NA NA NA NA NA NA 5871 FUN_023327 21 36 77 185 344 NA NA NA NA NA NA NA 5872 FUN_023015 136 249 84 122 100 NA NA NA NA NA NA NA 5873 FUN_023332 78 34 46 46 51 NA NA NA NA NA NA NA 5874 FUN_023016 611 275 282 604 415 NA NA NA NA NA NA NA 5875 FUN_023335 10 40 0 3 8 NA NA NA NA NA NA NA 5876 FUN_023017 94 76 52 45 48 NA NA NA NA NA NA NA 5877 FUN_026122 127 0 0 0 0 NA NA NA NA NA NA NA 5878 FUN_026121 1181 1073 360 907 4 NA NA NA NA NA NA NA 5879 FUN_035208 1383 979 910 1524 1367 ptg000025l:5134169-5136792 Q8TC84 2.01e-47 Fibronectin type 3 and ankyrin repeat domains protein 1 Homo sapiens (Human) negative regulation of apoptotic process [GO:0043066]; positive regulation of apoptotic process [GO:0043065]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of apoptotic process [GO:0042981] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005929; GO:0036064; GO:0042981; GO:0043065; GO:0043066; GO:0045893; GO:0051091; GO:0097546 5880 FUN_035209 72 47 54 137 10 NA NA NA NA NA NA NA 5881 FUN_035206 83 1587 10 38 20 NA NA NA NA NA NA NA 5882 FUN_035207 495 857 239 215 179 NA NA NA NA NA NA NA 5883 FUN_035205 30 981 10 12 124 NA NA NA NA NA NA NA 5884 FUN_035202 585 3927 159 185 13 NA NA NA NA NA NA NA 5885 FUN_035200 881 233 26 913 144 NA NA NA NA NA NA NA 5886 FUN_035201 1339 1383 217 1102 170 NA NA NA NA NA NA NA 5887 FUN_031188 351 37 142 193 169 NA NA NA NA NA NA NA 5888 FUN_031181 120 106 79 144 166 NA NA NA NA NA NA NA 5889 FUN_031180 253 143 156 278 129 NA NA NA NA NA NA NA 5890 FUN_031183 1013 758 379 775 720 NA NA NA NA NA NA NA 5891 FUN_031182 1503 861 757 1562 1549 ptg000023l:17435129-17438443 Q17QQ2 1.37e-35 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) Bos taurus (Bovine) methylation [GO:0032259]; xenobiotic metabolic process [GO:0006805] GO:0005737; GO:0006805; GO:0008119; GO:0032259; GO:1904047 5892 FUN_031182 1503 861 757 1562 1549 ptg000023l:17435129-17438443 Q17QQ2 1.06e-32 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) Bos taurus (Bovine) methylation [GO:0032259]; xenobiotic metabolic process [GO:0006805] GO:0005737; GO:0006805; GO:0008119; GO:0032259; GO:1904047 5893 FUN_031185 39 14 11 61 15 NA NA NA NA NA NA NA 5894 FUN_031184 451 255 194 325 224 NA NA NA NA NA NA NA 5895 FUN_031187 234 131 110 133 78 NA NA NA NA NA NA NA 5896 FUN_031186 3624 1582 1967 2825 3299 NA NA NA NA NA NA NA 5897 FUN_007235 0 41 0 0 56 NA NA NA NA NA NA NA 5898 FUN_039750 0 0 0 75 0 NA NA NA NA NA NA NA 5899 FUN_031233 474 444 524 278 1066 NA NA NA NA NA NA NA 5900 FUN_031232 7153 6235 4016 5630 3884 ptg000023l:18326440-18340258 Q7T0T9 5.88e-33 Cytosolic phospholipase A2 (cPLA2) (Phospholipase A2 group IVA) [Includes: Phospholipase A2 (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase); Lysophospholipase (EC 3.1.1.5)] Xenopus laevis (African clawed frog) phospholipid catabolic process [GO:0009395] GO:0004622; GO:0004623; GO:0005509; GO:0009395; GO:0031410; GO:0102545 5901 FUN_031231 81 18 31 26 147 ptg000023l:18294343-18298335 B8VIU6 5.19e-35 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 5902 FUN_031237 446 452 321 839 795 NA NA NA NA NA NA NA 5903 FUN_031236 425 249 187 361 561 NA NA NA NA NA NA NA 5904 FUN_031235 260 80 201 206 57 NA NA NA NA NA NA NA 5905 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 1.56e-72 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5906 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 1.56e-72 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5907 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 1.56e-72 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5908 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 1.16e-56 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5909 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 1.16e-56 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5910 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 1.16e-56 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5911 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 6.7e-47 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5912 FUN_031234 1112 217 220 526 1770 ptg000023l:18365715-18417934 P0CT40 6.7e-47 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 5913 FUN_031239 0 0 0 0 33 NA NA NA NA NA NA NA 5914 FUN_007580 0 0 0 0 12 NA NA NA NA NA NA NA 5915 FUN_007581 0 0 3 0 79 NA NA NA NA NA NA NA 5916 FUN_007587 0 39 0 0 0 NA NA NA NA NA NA NA 5917 FUN_007588 0 0 0 0 14 NA NA NA NA NA NA NA 5918 FUN_027409 0 0 3 0 10 NA NA NA NA NA NA NA 5919 FUN_027408 16 37 22 22 22 ptg000021l:4575903-4581823 P14381 1.22e-50 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 5920 FUN_027408 16 37 22 22 22 ptg000021l:4575903-4581823 P14381 1.22e-50 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 5921 FUN_027408 16 37 22 22 22 ptg000021l:4575903-4581823 P14381 1.22e-50 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 5922 FUN_027408 16 37 22 22 22 ptg000021l:4575903-4581823 P14381 1.22e-50 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 5923 FUN_027403 0 0 0 8 15 NA NA NA NA NA NA NA 5924 FUN_027400 0 49 3 0 0 NA NA NA NA NA NA NA 5925 FUN_006187 22 18 24 79 41 NA NA NA NA NA NA NA 5926 FUN_006186 60 43 56 209 108 NA NA NA NA NA NA NA 5927 FUN_006185 97 55 15 192 53 ptg000001l:8952173-8953826 Q7RTR2 2.63e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5928 FUN_006185 97 55 15 192 53 ptg000001l:8952173-8953826 Q7RTR2 3.56e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5929 FUN_006185 97 55 15 192 53 ptg000001l:8952173-8953826 Q7RTR2 8.44e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 5930 FUN_006182 0 0 0 0 6 NA NA NA NA NA NA NA 5931 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 2.86e-53 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5932 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 1.69e-52 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5933 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 1.9e-52 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5934 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 2.5e-52 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5935 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 1.4e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5936 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 7.58e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5937 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 9.54e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5938 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 1.48e-48 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5939 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 1.04e-47 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5940 FUN_037176 277 297 270 1674 1122 ptg000026l:6705016-6712987 Q7Z494 2.56e-41 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 5941 FUN_037177 0 91 0 64 0 NA NA NA NA NA NA NA 5942 FUN_037174 55 101 18 65 51 ptg000026l:6656412-6664439 Q76KP1 4.45e-22 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 5943 FUN_037175 691 481 35 422 123 ptg000026l:6666495-6693856 Q76KP1 1.66e-24 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 5944 FUN_037175 691 481 35 422 123 ptg000026l:6666495-6693856 Q76KP1 8.59e-24 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 5945 FUN_037172 1539 1147 1357 2357 1218 ptg000026l:6607788-6611651 Q76KP1 1.02e-23 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 5946 FUN_037173 16 115 8 47 46 ptg000026l:6641315-6653057 Q09575 8.08e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5947 FUN_037173 16 115 8 47 46 ptg000026l:6641315-6653057 Q09575 8.08e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5948 FUN_037173 16 115 8 47 46 ptg000026l:6641315-6653057 Q09575 8.08e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5949 FUN_037173 16 115 8 47 46 ptg000026l:6641315-6653057 Q09575 2.75e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5950 FUN_037173 16 115 8 47 46 ptg000026l:6641315-6653057 Q09575 2.75e-32 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 5951 FUN_037170 225 149 135 43 118 ptg000026l:6579474-6581037 P36514 7.72e-69 UDP-glucuronosyltransferase 2C1 (UDPGT 2C1) (EC 2.4.1.17) Oryctolagus cuniculus (Rabbit) lipid metabolic process [GO:0006629] GO:0005789; GO:0006629; GO:0015020 5952 FUN_037171 1580 1344 830 1049 1409 NA NA NA NA NA NA NA 5953 FUN_037179 2472 1715 74 3805 224 ptg000026l:6730055-6734030 Q7TNH6 1.24e-46 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 5954 FUN_037179 2472 1715 74 3805 224 ptg000026l:6730055-6734030 Q7TNH6 2.01e-45 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 5955 FUN_037179 2472 1715 74 3805 224 ptg000026l:6730055-6734030 Q7TNH6 5.07e-45 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 5956 FUN_037179 2472 1715 74 3805 224 ptg000026l:6730055-6734030 Q7TNH6 1.62e-41 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 5957 FUN_037179 2472 1715 74 3805 224 ptg000026l:6730055-6734030 Q7TNH6 1.47e-40 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 5958 FUN_037179 2472 1715 74 3805 224 ptg000026l:6730055-6734030 Q7TNH6 2.36e-22 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 5959 FUN_032528 1021 767 728 1038 1289 NA NA NA NA NA NA NA 5960 FUN_032529 23 19 35 45 33 NA NA NA NA NA NA NA 5961 FUN_032526 130 51 10 20 36 NA NA NA NA NA NA NA 5962 FUN_032527 139 97 79 161 66 NA NA NA NA NA NA NA 5963 FUN_032524 375 486 150 159 451 NA NA NA NA NA NA NA 5964 FUN_032525 59 55 11 165 12 NA NA NA NA NA NA NA 5965 FUN_032522 123 162 96 260 178 NA NA NA NA NA NA NA 5966 FUN_032523 40 91 4 65 36 NA NA NA NA NA NA NA 5967 FUN_032520 124 93 35 213 242 NA NA NA NA NA NA NA 5968 FUN_032521 227 76 66 45 20 NA NA NA NA NA NA NA 5969 FUN_019814 2 0 22 6 72 NA NA NA NA NA NA NA 5970 FUN_041810 607 188 200 336 324 NA NA NA NA NA NA NA 5971 FUN_041811 3625 1355 1291 3750 2056 NA NA NA NA NA NA NA 5972 FUN_041812 201 169 203 226 213 ptg000035l:7904682-7907179 A0JPI9 4.68e-48 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 5973 FUN_041813 839 774 204 941 725 NA NA NA NA NA NA NA 5974 FUN_041814 43 0 0 48 57 NA NA NA NA NA NA NA 5975 FUN_041815 1990 951 824 1368 1101 ptg000035l:7929172-7935747 Q8BWD2 1.46e-32 Inositol hexakisphosphate kinase 3 (InsP6 kinase 3) (EC 2.7.4.21) (Inositol hexaphosphate kinase 3) Mus musculus (Mouse) inositol phosphate biosynthetic process [GO:0032958]; locomotion [GO:0040011]; phosphatidylinositol metabolic process [GO:0046488]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein phosphorylation [GO:0006468] GO:0000827; GO:0000828; GO:0000831; GO:0000832; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0016301; GO:0032958; GO:0040011; GO:0046488; GO:0046854; GO:0052723; GO:0052724 5976 FUN_041816 5367 3910 2954 2517 2491 NA NA NA NA NA NA NA 5977 FUN_041817 964 1432 574 633 748 NA NA NA NA NA NA NA 5978 FUN_041818 3704 2257 2084 3102 2669 NA NA NA NA NA NA NA 5979 FUN_041819 36 0 0 17 11 NA NA NA NA NA NA NA 5980 FUN_001326 349 251 134 258 105 ntLink_6:11156063-11157165 Q4R4S5 3.38e-38 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 5981 FUN_001327 909 358 482 788 544 NA NA NA NA NA NA NA 5982 FUN_001324 629 391 185 419 316 NA NA NA NA NA NA NA 5983 FUN_001325 27150 24157 14395 25956 21154 NA NA NA NA NA NA NA 5984 FUN_001322 4180 6701 3563 7490 8562 NA NA NA NA NA NA NA 5985 FUN_001323 1813 596 913 1876 1122 NA NA NA NA NA NA NA 5986 FUN_033699 3687 3407 1323 2478 1607 NA NA NA NA NA NA NA 5987 FUN_033698 76 35 43 48 143 NA NA NA NA NA NA NA 5988 FUN_033697 0 0 0 19 22 NA NA NA NA NA NA NA 5989 FUN_033695 1001 884 514 789 665 ptg000024l:491277-493581 Q8K4Y7 2.66e-129 Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) Rattus norvegicus (Rat) proteoglycan biosynthetic process [GO:0030166] GO:0004382; GO:0005509; GO:0005789; GO:0016020; GO:0030166; GO:0032580; GO:0042803; GO:0043262; GO:0045134 5990 FUN_033694 4843 6427 4548 3327 2597 NA NA NA NA NA NA NA 5991 FUN_033693 4259 3936 2301 3122 1991 ptg000024l:478737-488747 Q5ZL16 6.96e-43 WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] GO:0000045; GO:0000407; GO:0000422; GO:0005764; GO:0005829; GO:0006497; GO:0009267; GO:0019898; GO:0032266; GO:0034045; GO:0034497; GO:0044804; GO:0080025 5992 FUN_033693 4259 3936 2301 3122 1991 ptg000024l:478737-488747 Q5ZL16 6.96e-43 WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] GO:0000045; GO:0000407; GO:0000422; GO:0005764; GO:0005829; GO:0006497; GO:0009267; GO:0019898; GO:0032266; GO:0034045; GO:0034497; GO:0044804; GO:0080025 5993 FUN_033693 4259 3936 2301 3122 1991 ptg000024l:478737-488747 Q5ZL16 6.96e-43 WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45B) Gallus gallus (Chicken) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; autophagy of nucleus [GO:0044804]; cellular response to starvation [GO:0009267]; protein lipidation [GO:0006497]; protein localization to phagophore assembly site [GO:0034497] GO:0000045; GO:0000407; GO:0000422; GO:0005764; GO:0005829; GO:0006497; GO:0009267; GO:0019898; GO:0032266; GO:0034045; GO:0034497; GO:0044804; GO:0080025 5994 FUN_033692 586 244 184 509 245 NA NA NA NA NA NA NA 5995 FUN_033691 3374 2254 1784 2734 3266 ptg000024l:461611-471202 A7SMR1 1.63e-23 Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) Nematostella vectensis (Starlet sea anemone) cap-dependent translational initiation [GO:0002191]; formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0002191; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0098808 5996 FUN_033691 3374 2254 1784 2734 3266 ptg000024l:461611-471202 A7SMR1 7.55e-23 Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) Nematostella vectensis (Starlet sea anemone) cap-dependent translational initiation [GO:0002191]; formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0002191; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0033290; GO:0098808 5997 FUN_033690 530 324 254 783 225 NA NA NA NA NA NA NA 5998 FUN_002668 1024 735 765 1929 3002 NA NA NA NA NA NA NA 5999 FUN_002669 316 129 125 138 138 NA NA NA NA NA NA NA 6000 FUN_002666 940 424 383 500 356 ntLink_8:5060643-5062502 A8MY62 1.07e-51 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 6001 FUN_002667 1930 1533 954 1326 911 ntLink_8:5062709-5063867 Q5I0S8 1.74e-83 Leukocyte elastase inhibitor (Serpin B1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0005737; GO:0010466 6002 FUN_002664 76 45 70 96 129 NA NA NA NA NA NA NA 6003 FUN_002665 79 12 74 125 58 NA NA NA NA NA NA NA 6004 FUN_002662 563 405 170 92 128 NA NA NA NA NA NA NA 6005 FUN_002663 131 0 92 0 226 NA NA NA NA NA NA NA 6006 FUN_002660 3980 2789 1839 4019 3858 NA NA NA NA NA NA NA 6007 FUN_002661 7727 5278 3309 5855 3522 NA NA NA NA NA NA NA 6008 FUN_012759 1660 2041 676 982 730 NA NA NA NA NA NA NA 6009 FUN_012758 489 779 291 1275 820 ptg000008l:12247335-12252833 Q17QV9 1.02e-55 Serine/threonine-protein kinase 40 (EC 2.7.11.1) Bos taurus (Bovine) glycogen metabolic process [GO:0005977]; lung alveolus development [GO:0048286]; lung morphogenesis [GO:0060425]; multicellular organism growth [GO:0035264]; negative regulation of apoptotic process [GO:0043066]; protein phosphorylation [GO:0006468]; regulation of gene expression [GO:0010468]; regulation of MAPK cascade [GO:0043408]; respiratory system process [GO:0003016] GO:0003016; GO:0004674; GO:0005524; GO:0005654; GO:0005829; GO:0005977; GO:0006468; GO:0010468; GO:0035264; GO:0043066; GO:0043408; GO:0048286; GO:0060425; GO:0106310 6010 FUN_012753 174 0 24 22 20 NA NA NA NA NA NA NA 6011 FUN_012752 636 517 405 370 401 NA NA NA NA NA NA NA 6012 FUN_012751 160 78 44 87 72 NA NA NA NA NA NA NA 6013 FUN_012750 0 0 3 97 46 NA NA NA NA NA NA NA 6014 FUN_012757 460 235 533 894 737 NA NA NA NA NA NA NA 6015 FUN_012756 58 0 43 6 4 NA NA NA NA NA NA NA 6016 FUN_012754 356 93 263 513 383 NA NA NA NA NA NA NA 6017 FUN_006969 18 0 0 0 26 NA NA NA NA NA NA NA 6018 FUN_016449 907 466 570 1415 2300 ptg000011l:3204739-3210919 Q9UHI7 1.79e-62 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 6019 FUN_016449 907 466 570 1415 2300 ptg000011l:3204739-3210919 Q9UHI7 1.79e-62 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 6020 FUN_016449 907 466 570 1415 2300 ptg000011l:3204739-3210919 Q9UHI7 1.79e-62 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 6021 FUN_016448 505 248 225 188 405 NA NA NA NA NA NA NA 6022 FUN_016443 352 190 238 160 136 NA NA NA NA NA NA NA 6023 FUN_006960 32 0 3 7 118 NA NA NA NA NA NA NA 6024 FUN_006963 294 222 38 132 354 NA NA NA NA NA NA NA 6025 FUN_016447 3679 2464 2122 4347 3673 NA NA NA NA NA NA NA 6026 FUN_016446 748 615 518 997 712 NA NA NA NA NA NA NA 6027 FUN_016445 2995 1832 1313 2025 1183 NA NA NA NA NA NA NA 6028 FUN_016444 3480 2171 1665 2467 2511 NA NA NA NA NA NA NA 6029 FUN_000270 3749 3695 1372 4578 2331 ntLink_6:940805-944220 Q05AQ3 3.29e-45 Mitochondrial coenzyme A transporter SLC25A42 (Solute carrier family 25 member 42) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ADP transport [GO:0015866]; AMP transport [GO:0080121]; ATP transport [GO:0015867]; coenzyme A transmembrane transport [GO:0035349] GO:0005347; GO:0005739; GO:0005743; GO:0015217; GO:0015228; GO:0015866; GO:0015867; GO:0035349; GO:0043262; GO:0080121; GO:0080122 6030 FUN_003214 29 0 13 20 65 NA NA NA NA NA NA NA 6031 FUN_003215 50 0 0 0 16 NA NA NA NA NA NA NA 6032 FUN_003210 45 0 34 0 42 NA NA NA NA NA NA NA 6033 FUN_003212 0 9 0 0 0 NA NA NA NA NA NA NA 6034 FUN_003218 20 0 9 13 39 NA NA NA NA NA NA NA 6035 FUN_003219 0 9 27 0 8 NA NA NA NA NA NA NA 6036 FUN_005741 396 927 446 230 137 ptg000001l:3471331-3472428 A0A1L4BJ98 2.14e-30 Dermonecrotic toxin Hl-PLD1 (EC 4.6.1.-) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Hemiscorpius lepturus (Scorpion) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 6037 FUN_014430 53 41 54 0 21 NA NA NA NA NA NA NA 6038 FUN_014431 11 0 23 0 27 NA NA NA NA NA NA NA 6039 FUN_041668 264 113 45 706 311 ptg000035l:6399804-6416023 O88871 5.95e-28 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 6040 FUN_014432 25 28 20 24 25 NA NA NA NA NA NA NA 6041 FUN_013088 2026 1696 1423 3246 2549 NA NA NA NA NA NA NA 6042 FUN_013089 745 924 402 909 420 ptg000008l:19357805-19377844 O93384 9.49e-29 S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (SAND) (Radical S-adenosyl methionine domain-containing protein 2) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) (Viperin) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) defense response to virus [GO:0051607]; innate immune response [GO:0045087] GO:0003824; GO:0005789; GO:0045087; GO:0046872; GO:0051539; GO:0051607 6043 FUN_028729 111 33 10 29 19 NA NA NA NA NA NA NA 6044 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 8.19e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6045 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 9.92e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6046 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 1.28e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6047 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 4.76e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6048 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 2.04e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6049 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 1.35e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6050 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 1.53e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6051 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 3.11e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6052 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 5.36e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6053 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 8.23e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6054 FUN_028728 93 42 7 91 139 ptg000022l:3238278-3240861 Q96AY4 2.08e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6055 FUN_017820 1768 1489 1056 1694 898 NA NA NA NA NA NA NA 6056 FUN_028722 16 60 0 66 111 ptg000022l:3196159-3201980 Q96AY4 1.36e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6057 FUN_028722 16 60 0 66 111 ptg000022l:3196159-3201980 Q96AY4 2.35e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6058 FUN_028722 16 60 0 66 111 ptg000022l:3196159-3201980 Q96AY4 4.51e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6059 FUN_028722 16 60 0 66 111 ptg000022l:3196159-3201980 Q96AY4 4.88e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6060 FUN_028722 16 60 0 66 111 ptg000022l:3196159-3201980 Q96AY4 3.03e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6061 FUN_028721 0 0 0 30 0 NA NA NA NA NA NA NA 6062 FUN_028727 88 205 126 208 112 NA NA NA NA NA NA NA 6063 FUN_013085 1805 1009 1442 1880 1922 NA NA NA NA NA NA NA 6064 FUN_028725 120 253 0 175 200 NA NA NA NA NA NA NA 6065 FUN_013427 273 195 0 139 40 NA NA NA NA NA NA NA 6066 FUN_026632 237 232 113 103 95 ptg000020l:11717453-11718251 E9QAG8 2.93e-75 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 6067 FUN_026632 237 232 113 103 95 ptg000020l:11717453-11718251 E9QAG8 1.27e-70 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 6068 FUN_026632 237 232 113 103 95 ptg000020l:11717453-11718251 E9QAG8 2.15e-69 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 6069 FUN_026632 237 232 113 103 95 ptg000020l:11717453-11718251 E9QAG8 1.16e-67 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 6070 FUN_026632 237 232 113 103 95 ptg000020l:11717453-11718251 E9QAG8 4.15e-52 Zinc finger protein 431 (Zinc finger protein 932) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0030154; GO:0042826; GO:0043433; GO:0045668; GO:0046872 6071 FUN_013424 0 0 0 6 124 NA NA NA NA NA NA NA 6072 FUN_014437 1767 942 963 1870 1712 NA NA NA NA NA NA NA 6073 FUN_043508 1013 1160 515 787 941 ptg000047l:9411585-9417575 Q6AY53 3.95e-40 Deoxyhypusine synthase (DHS) (EC 2.5.1.46) Rattus norvegicus (Rat) glucose homeostasis [GO:0042593]; peptidyl-lysine modification to peptidyl-hypusine [GO:0008612]; positive regulation of T cell proliferation [GO:0042102]; spermidine catabolic process [GO:0046203]; spermidine metabolic process [GO:0008216] GO:0005737; GO:0008216; GO:0008612; GO:0034038; GO:0042102; GO:0042593; GO:0042802; GO:0046203 6074 FUN_043509 933 825 664 1028 1083 NA NA NA NA NA NA NA 6075 FUN_043500 1902 1280 1141 3507 2104 ptg000047l:9353150-9366298 Q9DCD2 2.07e-45 Pre-mRNA-splicing factor SYF1 (XPA-binding protein 2) Mus musculus (Mouse) blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; DNA-templated transcription [GO:0006351]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000349; GO:0000398; GO:0000974; GO:0001824; GO:0005634; GO:0005654; GO:0006283; GO:0006351; GO:0021987; GO:0043231; GO:0071007; GO:0071013; GO:0071014 6076 FUN_043500 1902 1280 1141 3507 2104 ptg000047l:9353150-9366298 Q9DCD2 1.19e-21 Pre-mRNA-splicing factor SYF1 (XPA-binding protein 2) Mus musculus (Mouse) blastocyst development [GO:0001824]; cerebral cortex development [GO:0021987]; DNA-templated transcription [GO:0006351]; generation of catalytic spliceosome for first transesterification step [GO:0000349]; mRNA splicing, via spliceosome [GO:0000398]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000349; GO:0000398; GO:0000974; GO:0001824; GO:0005634; GO:0005654; GO:0006283; GO:0006351; GO:0021987; GO:0043231; GO:0071007; GO:0071013; GO:0071014 6077 FUN_043501 2410 1991 1518 1155 1518 ptg000047l:9366590-9368396 Q5BIN5 2.52e-26 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase Pin1) (PPIase Pin1) (Rotamase Pin1) Bos taurus (Bovine) cell cycle [GO:0007049]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of cell motility [GO:2000146]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein binding [GO:0032091]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization to nucleus [GO:1900180]; regulation of protein stability [GO:0031647]; response to hypoxia [GO:0001666] GO:0000413; GO:0001666; GO:0001934; GO:0003755; GO:0005634; GO:0005737; GO:0005829; GO:0007049; GO:0008013; GO:0016607; GO:0016859; GO:0030496; GO:0030512; GO:0031434; GO:0031647; GO:0032091; GO:0032092; GO:0032465; GO:0032794; GO:0036064; GO:0042127; GO:0042177; GO:0043547; GO:0045944; GO:0050815; GO:0050816; GO:0050821; GO:0051443; GO:0060393; GO:0070373; GO:0090263; GO:0098978; GO:0099524; GO:1900180; GO:1902430; GO:2000146 6078 FUN_043502 2139 3226 2282 1321 860 NA NA NA NA NA NA NA 6079 FUN_043503 1528 1234 743 1213 896 ptg000047l:9373816-9378404 Q91398 3.96e-36 Casein kinase II subunit beta (CK II beta) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of protein serine/threonine phosphatase activity [GO:0080163]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0005956; GO:0016055; GO:0019887; GO:0046872; GO:0080163 6080 FUN_043504 871 709 776 1251 484 NA NA NA NA NA NA NA 6081 FUN_043505 12774 21382 10803 17272 6529 NA NA NA NA NA NA NA 6082 FUN_043506 39 11 0 13 97 NA NA NA NA NA NA NA 6083 FUN_043507 389 395 448 704 623 NA NA NA NA NA NA NA 6084 FUN_042679 4 5 32 58 142 NA NA NA NA NA NA NA 6085 FUN_042678 4 5 44 17 191 NA NA NA NA NA NA NA 6086 FUN_042671 238 292 86 207 130 NA NA NA NA NA NA NA 6087 FUN_042670 253 167 31 154 86 NA NA NA NA NA NA NA 6088 FUN_042673 131 48 33 51 131 ptg000039l:1006521-1022531 Q5RHH4 6.92e-32 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 6089 FUN_042673 131 48 33 51 131 ptg000039l:1006521-1022531 Q5RHH4 6.92e-32 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 6090 FUN_042672 299 302 309 403 668 ptg000039l:996587-1005133 Q5RHH4 4.48e-28 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 6091 FUN_042672 299 302 309 403 668 ptg000039l:996587-1005133 Q5RHH4 4.48e-28 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 6092 FUN_042672 299 302 309 403 668 ptg000039l:996587-1005133 Q5RHH4 4.48e-28 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 6093 FUN_042675 103 88 78 63 70 NA NA NA NA NA NA NA 6094 FUN_029941 0 0 0 23 16 NA NA NA NA NA NA NA 6095 FUN_042677 2 2 3 4 9 NA NA NA NA NA NA NA 6096 FUN_042676 0 0 11 10 1 NA NA NA NA NA NA NA 6097 FUN_033806 33 0 9 0 48 NA NA NA NA NA NA NA 6098 FUN_039863 185 314 190 318 350 ptg000031l:1046294-1048246 B5XF11 1.03e-94 Lysine-specific demethylase 8 (EC 1.14.11.27) (JmjC domain-containing protein 5) (Jumonji domain-containing protein 5) Salmo salar (Atlantic salmon) chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; G2/M transition of mitotic cell cycle [GO:0000086]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000086; GO:0003682; GO:0005634; GO:0006325; GO:0032922; GO:0045893; GO:0046872; GO:0051864; GO:0140680 6099 FUN_026630 8 22 0 6 6 NA NA NA NA NA NA NA 6100 FUN_033804 162 105 69 198 204 NA NA NA NA NA NA NA 6101 FUN_009359 47 0 0 40 31 NA NA NA NA NA NA NA 6102 FUN_009358 691 108 380 1143 750 NA NA NA NA NA NA NA 6103 FUN_003935 1866 1467 680 1629 945 NA NA NA NA NA NA NA 6104 FUN_009353 1137 460 583 924 602 NA NA NA NA NA NA NA 6105 FUN_009352 76 26 65 28 147 NA NA NA NA NA NA NA 6106 FUN_009351 28 87 6 64 53 ptg000004l:5626400-5627708 P08510 3.12e-103 Potassium voltage-gated channel protein Shaker (Protein minisleep) Drosophila melanogaster (Fruit fly) action potential [GO:0001508]; axon extension [GO:0048675]; behavioral response to ether [GO:0048150]; cellular response to dopamine [GO:1903351]; courtship behavior [GO:0007619]; detection of visible light [GO:0009584]; larval locomotory behavior [GO:0008345]; learning or memory [GO:0007611]; mating behavior, sex discrimination [GO:0048047]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of membrane potential [GO:0045838]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; proboscis extension reflex [GO:0007637]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, sleep [GO:0045187]; regulation of ion transmembrane transport [GO:0034765]; regulation of synaptic activity [GO:0060025]; sensory perception of taste [GO:0050909]; sleep [GO:0030431] GO:0001508; GO:0005249; GO:0005251; GO:0006813; GO:0007611; GO:0007619; GO:0007637; GO:0008076; GO:0008345; GO:0009584; GO:0016020; GO:0022843; GO:0030431; GO:0034765; GO:0045187; GO:0045838; GO:0045938; GO:0048047; GO:0048150; GO:0048675; GO:0050909; GO:0051260; GO:0060025; GO:0071805; GO:1903351 6107 FUN_009350 112 76 35 105 80 ptg000004l:5606913-5617641 Q9I830 1.18e-69 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 6108 FUN_009357 500 433 290 811 809 NA NA NA NA NA NA NA 6109 FUN_009356 535 804 24 1136 505 NA NA NA NA NA NA NA 6110 FUN_009355 157 34 35 175 114 NA NA NA NA NA NA NA 6111 FUN_039867 239 74 55 188 224 ptg000031l:1091704-1092523 A9CMA6 2.48e-24 Transmembrane protein 163 (Synaptic vesicle membrane protein of 31 kDa) Rattus norvegicus (Rat) zinc ion import into synaptic vesicle [GO:0099180] GO:0005886; GO:0008270; GO:0016020; GO:0030672; GO:0031901; GO:0097708; GO:0099180 6112 FUN_039864 1776 3887 1552 2332 864 NA NA NA NA NA NA NA 6113 FUN_039865 2021 2344 1084 2267 1886 NA NA NA NA NA NA NA 6114 FUN_009124 13 190 75 19 14 ptg000004l:2966709-2970432 Q96AY4 5.31e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6115 FUN_009124 13 190 75 19 14 ptg000004l:2966709-2970432 Q96AY4 8.82e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6116 FUN_009124 13 190 75 19 14 ptg000004l:2966709-2970432 Q96AY4 9.54e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6117 FUN_009124 13 190 75 19 14 ptg000004l:2966709-2970432 Q96AY4 6.47e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6118 FUN_009124 13 190 75 19 14 ptg000004l:2966709-2970432 Q96AY4 1.23e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6119 FUN_009124 13 190 75 19 14 ptg000004l:2966709-2970432 Q96AY4 8e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6120 FUN_022608 350 272 194 410 266 NA NA NA NA NA NA NA 6121 FUN_022609 1648 1491 809 1193 1161 NA NA NA NA NA NA NA 6122 FUN_022606 2275 1918 1232 1881 1831 ptg000016l:11267063-11294947 P0CT40 7.78e-65 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 6123 FUN_007247 0 0 0 0 13 NA NA NA NA NA NA NA 6124 FUN_022604 1416 1009 877 854 1072 NA NA NA NA NA NA NA 6125 FUN_022605 1405 1028 798 895 2032 NA NA NA NA NA NA NA 6126 FUN_022602 2259 2510 2059 4097 4525 ptg000016l:11243652-11244798 Q91VY9 1.34e-62 Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273] GO:0003676; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0008270; GO:0008631; GO:0030687; GO:0033674; GO:0042273; GO:0043065; GO:0043410; GO:0046330; GO:1990275 6127 FUN_022602 2259 2510 2059 4097 4525 ptg000016l:11243652-11244798 Q91VY9 1.01e-26 Cytoplasmic 60S subunit biogenesis factor ZNF622 (Zinc finger protein 622) Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; ribosomal large subunit biogenesis [GO:0042273] GO:0003676; GO:0005654; GO:0005730; GO:0005794; GO:0005829; GO:0008270; GO:0008631; GO:0030687; GO:0033674; GO:0042273; GO:0043065; GO:0043410; GO:0046330; GO:1990275 6128 FUN_022603 1140 1149 721 794 717 NA NA NA NA NA NA NA 6129 FUN_022600 548 172 851 821 1302 NA NA NA NA NA NA NA 6130 FUN_014856 11131 17566 7888 9549 6028 ptg000009l:3738270-3740560 A7SXK3 9.27e-29 Transmembrane emp24 domain-containing protein Nematostella vectensis (Starlet sea anemone) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0030134; GO:0030659 6131 FUN_009127 0 14 106 21 0 NA NA NA NA NA NA NA 6132 FUN_039767 34 7 0 43 4 NA NA NA NA NA NA NA 6133 FUN_009120 28 0 0 0 0 NA NA NA NA NA NA NA 6134 FUN_022764 16 36 45 43 55 NA NA NA NA NA NA NA 6135 FUN_029924 0 0 0 0 38 NA NA NA NA NA NA NA 6136 FUN_022766 373 414 394 651 369 NA NA NA NA NA NA NA 6137 FUN_042904 3143 2490 1323 4422 3668 NA NA NA NA NA NA NA 6138 FUN_002942 0 0 0 0 7 NA NA NA NA NA NA NA 6139 FUN_010067 5 0 0 7 0 NA NA NA NA NA NA NA 6140 FUN_014854 1283 819 422 797 845 NA NA NA NA NA NA NA 6141 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 2.44e-102 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6142 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 2.44e-102 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6143 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 2.44e-102 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6144 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 6.34e-62 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6145 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 5.44e-60 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6146 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 5.44e-60 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6147 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 7.29e-59 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6148 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 2.66e-53 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6149 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 3.28e-53 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6150 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 1.67e-39 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6151 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 2.37e-33 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6152 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 1.98e-32 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6153 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 1.03e-30 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6154 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 8.04e-30 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6155 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 1.24e-29 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6156 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 3e-26 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6157 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 2.88e-24 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6158 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 9.02e-24 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6159 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 9.02e-24 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6160 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 9.89e-23 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6161 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 6e-22 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6162 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 7.04e-22 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6163 FUN_014855 9425 6368 5163 9877 7070 ptg000009l:3713519-3737864 P34369 1.25e-21 Pre-mRNA-splicing factor 8 homolog Caenorhabditis elegans spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005682; GO:0008237; GO:0017070; GO:0030619; GO:0030620; GO:0030623; GO:0071013; GO:0097157 6164 FUN_009829 393 107 143 338 266 NA NA NA NA NA NA NA 6165 FUN_009828 97 48 173 114 38 NA NA NA NA NA NA NA 6166 FUN_009821 692 461 313 395 382 NA NA NA NA NA NA NA 6167 FUN_009820 2745 2460 919 2818 2903 NA NA NA NA NA NA NA 6168 FUN_009823 45 148 0 47 75 ptg000004l:12154451-12155797 Q5XJ34 5.28e-31 BTB/POZ domain-containing protein kctd15-like Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; canonical Wnt signaling pathway [GO:0060070]; neural crest cell differentiation [GO:0014033]; pharyngeal system development [GO:0060037]; protein homooligomerization [GO:0051260]; regulation of RNA biosynthetic process [GO:2001141] GO:0007420; GO:0014033; GO:0051260; GO:0060037; GO:0060070; GO:2001141 6169 FUN_009822 4056 3163 1948 4243 2556 NA NA NA NA NA NA NA 6170 FUN_009825 14 254 0 0 151 ptg000004l:12170612-12171505 Q6DG99 1.79e-30 BTB/POZ domain-containing protein KCTD6 Danio rerio (Zebrafish) (Brachydanio rerio) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 6171 FUN_009824 0 38 0 1 0 NA NA NA NA NA NA NA 6172 FUN_009827 411 516 316 230 232 ptg000004l:12181988-12224002 Q96AY4 3.39e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6173 FUN_009827 411 516 316 230 232 ptg000004l:12181988-12224002 Q96AY4 1.44e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6174 FUN_009827 411 516 316 230 232 ptg000004l:12181988-12224002 Q96AY4 5.12e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6175 FUN_009827 411 516 316 230 232 ptg000004l:12181988-12224002 Q96AY4 5.18e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6176 FUN_009826 104 59 140 238 247 ptg000004l:12171909-12178038 Q91WI7 3.57e-27 KICSTOR complex protein ITFG2 (Integrin-alpha FG-GAP repeat-containing protein 2) Mus musculus (Mouse) cellular response to amino acid starvation [GO:0034198]; cellular response to glucose starvation [GO:0042149]; germinal center B cell differentiation [GO:0002314]; negative regulation of TORC1 signaling [GO:1904262]; regulation of TOR signaling [GO:0032006] GO:0002314; GO:0005654; GO:0005765; GO:0005829; GO:0032006; GO:0034198; GO:0042149; GO:0140007; GO:1904262 6177 FUN_000905 1128 895 1282 2579 1420 NA NA NA NA NA NA NA 6178 FUN_000904 0 0 32 3 62 NA NA NA NA NA NA NA 6179 FUN_000907 5 104 10 4 443 NA NA NA NA NA NA NA 6180 FUN_000906 6 0 42 2 27 NA NA NA NA NA NA NA 6181 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 1.3e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6182 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 1.41e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6183 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 2.92e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6184 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 1.59e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6185 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 1.39e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6186 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 8.84e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6187 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 4.65e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6188 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 2.63e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6189 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 1.42e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6190 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 6.95e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6191 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 2.03e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6192 FUN_024529 7 93 90 88 78 ptg000018l:7921854-7947207 Q80XJ3 1.37e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 6193 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 2.49e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6194 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 4.17e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6195 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 1.67e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6196 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 1.87e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6197 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 7.58e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6198 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 5.35e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6199 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 6.78e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6200 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 6.11e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6201 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 4.91e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6202 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 8.38e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6203 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 1.55e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6204 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 6.42e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6205 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 1.14e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6206 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 2.89e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6207 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 6.6e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6208 FUN_024528 183 235 92 202 262 ptg000018l:7886055-7895773 Q96AY4 5.36e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6209 FUN_013958 8 24 0 0 12 NA NA NA NA NA NA NA 6210 FUN_024525 352 308 118 164 182 NA NA NA NA NA NA NA 6211 FUN_000901 18 0 12 0 33 NA NA NA NA NA NA NA 6212 FUN_024527 2322 984 788 709 786 ptg000018l:7868431-7870037 Q29RI9 3.12e-51 Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0006556; GO:0006730; GO:0048269; GO:0048270 6213 FUN_024527 2322 984 788 709 786 ptg000018l:7868431-7870037 Q29RI9 5.18e-28 Methionine adenosyltransferase 2 subunit beta (Methionine adenosyltransferase II beta) (MAT II beta) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0006556; GO:0006730; GO:0048269; GO:0048270 6214 FUN_024526 732 472 272 410 452 NA NA NA NA NA NA NA 6215 FUN_024521 0 2 6 0 216 NA NA NA NA NA NA NA 6216 FUN_024520 38 41 19 140 56 NA NA NA NA NA NA NA 6217 FUN_029383 467 601 0 0 839 NA NA NA NA NA NA NA 6218 FUN_000903 10 0 13 0 23 NA NA NA NA NA NA NA 6219 FUN_014853 86 90 58 30 72 NA NA NA NA NA NA NA 6220 FUN_029381 0 322 0 0 189 NA NA NA NA NA NA NA 6221 FUN_015150 224 322 0 0 101 ptg000009l:6776905-6798348 P10394 1.72e-67 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 6222 FUN_015151 26 10 7 14 27 NA NA NA NA NA NA NA 6223 FUN_015152 820 412 497 587 414 NA NA NA NA NA NA NA 6224 FUN_015153 418 248 74 196 267 NA NA NA NA NA NA NA 6225 FUN_015154 2282 1630 1412 2180 1632 ptg000009l:6824025-6848876 Q5RIW8 4.19e-21 Mediator of RNA polymerase II transcription subunit 23 (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) Danio rerio (Zebrafish) (Brachydanio rerio) circulatory system development [GO:0072359]; negative regulation of neurogenesis [GO:0050768]; pigmentation [GO:0043473]; positive regulation of gene expression [GO:0010628]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005667; GO:0006357; GO:0010628; GO:0016592; GO:0043473; GO:0050768; GO:0072359 6226 FUN_015155 60 52 337 291 88 NA NA NA NA NA NA NA 6227 FUN_015156 1340 965 640 1217 1248 NA NA NA NA NA NA NA 6228 FUN_015157 4650 5433 56 57 1928 NA NA NA NA NA NA NA 6229 FUN_015158 2990 2540 1072 1826 1008 NA NA NA NA NA NA NA 6230 FUN_015159 33 8 0 32 31 NA NA NA NA NA NA NA 6231 FUN_014850 7 0 0 4 0 NA NA NA NA NA NA NA 6232 FUN_024297 8 20 16 7 0 NA NA NA NA NA NA NA 6233 FUN_024296 0 40 0 0 0 NA NA NA NA NA NA NA 6234 FUN_024295 71 130 7 103 13 ptg000018l:4472290-4475949 E9Q5R7 4.28e-48 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 6235 FUN_024294 0 24 0 0 0 NA NA NA NA NA NA NA 6236 FUN_024293 0 12 39 61 17 ptg000018l:4464018-4465213 Q66TN7 1.01e-21 Ovochymase-2 (EC 3.4.21.120) (Oviductal protease) (Oviductin) Rhinella arenarum (Argentine common toad) (Bufo arenarum) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508; GO:0046872 6237 FUN_024292 0 21 41 12 0 NA NA NA NA NA NA NA 6238 FUN_024291 44 11 0 0 0 NA NA NA NA NA NA NA 6239 FUN_024290 29 0 0 0 192 ptg000018l:4427908-4430521 Q9Y239 4.58e-23 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0006952; GO:0006954; GO:0007165; GO:0007249; GO:0007254; GO:0008656; GO:0009595; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042834; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 6240 FUN_038577 2799 1496 1272 2878 1856 NA NA NA NA NA NA NA 6241 FUN_038576 1480 726 824 1647 2119 NA NA NA NA NA NA NA 6242 FUN_038575 1102 1692 763 1168 782 NA NA NA NA NA NA NA 6243 FUN_038574 214 234 90 197 149 NA NA NA NA NA NA NA 6244 FUN_038573 3125 2682 1791 3244 1934 NA NA NA NA NA NA NA 6245 FUN_038572 336 154 206 198 312 NA NA NA NA NA NA NA 6246 FUN_038571 357 1257 351 365 214 ptg000027l:8849151-8855600 Q75V66 3.76e-119 Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) Homo sapiens (Human) chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; ion transmembrane transport [GO:0034220]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005789; GO:0005886; GO:0006821; GO:0031982; GO:0034220; GO:0046983; GO:0055085; GO:1902476 6247 FUN_038570 0 9 0 0 0 NA NA NA NA NA NA NA 6248 FUN_038579 26 17 29 0 24 ptg000027l:8966745-8967267 P84239 7.27e-94 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6249 FUN_038578 33 0 0 44 25 NA NA NA NA NA NA NA 6250 FUN_041599 584 369 96 414 168 NA NA NA NA NA NA NA 6251 FUN_041598 648 68 157 887 451 NA NA NA NA NA NA NA 6252 FUN_019815 4 0 19 0 44 NA NA NA NA NA NA NA 6253 FUN_013870 0 16 0 8 0 NA NA NA NA NA NA NA 6254 FUN_013872 191 134 51 169 152 NA NA NA NA NA NA NA 6255 FUN_041595 1477 1298 1105 2812 2052 NA NA NA NA NA NA NA 6256 FUN_041594 5479 3891 2567 4807 3266 NA NA NA NA NA NA NA 6257 FUN_020999 9 0 0 0 0 NA NA NA NA NA NA NA 6258 FUN_015844 0 0 0 33 0 NA NA NA NA NA NA NA 6259 FUN_020990 0 0 15 0 17 NA NA NA NA NA NA NA 6260 FUN_015849 15 6 4 17 3 NA NA NA NA NA NA NA 6261 FUN_039220 3 0 3 0 27 NA NA NA NA NA NA NA 6262 FUN_024537 10 57 36 503 82 ptg000018l:8053426-8056828 Q96AY4 5.65e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6263 FUN_024537 10 57 36 503 82 ptg000018l:8053426-8056828 Q96AY4 2.01e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6264 FUN_024537 10 57 36 503 82 ptg000018l:8053426-8056828 Q96AY4 5.23e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6265 FUN_029658 33 19 220 33 203 ptg000023l:4196890-4198825 E7FAM5 1.31e-41 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 6266 FUN_029659 0 0 10 0 11 NA NA NA NA NA NA NA 6267 FUN_027176 0 0 0 5 33 NA NA NA NA NA NA NA 6268 FUN_027179 0 0 40 17 49 NA NA NA NA NA NA NA 6269 FUN_012591 281 119 184 150 220 ptg000008l:10163618-10174744 Q08DI8 1.92e-36 Pseudouridylate synthase 7 homolog (EC 5.4.99.-) Bos taurus (Bovine) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mesoderm development [GO:2000380]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0003723; GO:0005634; GO:0006357; GO:0006397; GO:0008380; GO:0009982; GO:0017148; GO:0031119; GO:1902036; GO:1990481; GO:2000380 6270 FUN_012591 281 119 184 150 220 ptg000008l:10163618-10174744 Q08DI8 5.52e-22 Pseudouridylate synthase 7 homolog (EC 5.4.99.-) Bos taurus (Bovine) mRNA processing [GO:0006397]; mRNA pseudouridine synthesis [GO:1990481]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mesoderm development [GO:2000380]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA splicing [GO:0008380]; tRNA pseudouridine synthesis [GO:0031119] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0003723; GO:0005634; GO:0006357; GO:0006397; GO:0008380; GO:0009982; GO:0017148; GO:0031119; GO:1902036; GO:1990481; GO:2000380 6271 FUN_012590 1347 998 759 795 509 ptg000008l:10158328-10163416 Q53FA7 5.37e-36 Quinone oxidoreductase PIG3 (EC 1.6.5.5) (NADPH:quinone reductase PIG3) (Tumor protein p53-inducible protein 3) (Protein PIG3) (p53-induced gene 3 protein) Homo sapiens (Human) NADP metabolic process [GO:0006739] GO:0003960; GO:0005829; GO:0006739; GO:0016651; GO:0042803; GO:0048038; GO:0070402 6272 FUN_012593 170 52 19 116 116 NA NA NA NA NA NA NA 6273 FUN_012592 73 0 19 45 51 NA NA NA NA NA NA NA 6274 FUN_012595 2407 2436 1216 1904 1895 ptg000008l:10210325-10221408 Q9VT57 3.06e-21 Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (DmCdk8) (Mediator complex subunit Cdk8) (Mediator of RNA polymerase II transcription subunit Cdk8) Drosophila melanogaster (Fruit fly) chaeta development [GO:0022416]; G1/S transition of mitotic cell cycle [GO:0000082]; imaginal disc-derived leg segmentation [GO:0036011]; positive regulation of autophagy [GO:0010508]; protein phosphorylation [GO:0006468]; sex comb development [GO:0045498]; snRNA 3'-end processing [GO:0034472] GO:0000082; GO:0004693; GO:0005524; GO:0005634; GO:0006468; GO:0008353; GO:0010508; GO:0016301; GO:0016592; GO:0022416; GO:0034472; GO:0036011; GO:0045498; GO:0106310 6275 FUN_029655 185 95 37 81 131 ptg000023l:4155989-4166540 E7FAM5 4.38e-65 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 6276 FUN_029655 185 95 37 81 131 ptg000023l:4155989-4166540 E7FAM5 2.68e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 6277 FUN_012597 59 65 99 133 72 NA NA NA NA NA NA NA 6278 FUN_005345 80 3 25 47 136 NA NA NA NA NA NA NA 6279 FUN_023216 3599 3155 1146 2338 1690 ptg000017l:5124411-5125274 Q90XN9 6.71e-34 Homeobox protein HMX3-B (Homeobox protein H6 family member 3-B) (Homeobox protein Nkx-5.1.2) (OlNkx-5.1.2) Oryzias latipes (Japanese rice fish) (Japanese killifish) cell differentiation [GO:0030154]; nervous system development [GO:0007399]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007399; GO:0030154 6280 FUN_023217 6888 9062 3198 5707 3629 NA NA NA NA NA NA NA 6281 FUN_023214 32 27 25 22 41 NA NA NA NA NA NA NA 6282 FUN_023215 116 8 44 76 24 ptg000017l:5090604-5097540 Q75W95 2.22e-41 NK1 transcription factor-related protein 1 (Homeodomain protein Sax2) (NK1 transcription factor related 2-like,b) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030154 6283 FUN_023212 54 15 62 47 78 NA NA NA NA NA NA NA 6284 FUN_023213 2409 1978 1889 1912 2216 ptg000017l:5064379-5083126 Q3UV71 1.1e-21 Protein O-mannosyl-transferase TMTC1 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 1) Mus musculus (Mouse) protein O-linked mannosylation [GO:0035269]; RNA processing [GO:0006396] GO:0000030; GO:0004169; GO:0005739; GO:0005783; GO:0006396; GO:0016020; GO:0035269 6285 FUN_023210 1108 436 615 653 557 ptg000017l:5036817-5039497 Q9WYP5 8.08e-47 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 6286 FUN_023211 1719 1046 447 794 793 NA NA NA NA NA NA NA 6287 FUN_023218 19 0 12 1 4 NA NA NA NA NA NA NA 6288 FUN_023219 82 0 16 56 19 NA NA NA NA NA NA NA 6289 FUN_014003 1 0 2 7 0 NA NA NA NA NA NA NA 6290 FUN_014005 1 1 2 8 0 NA NA NA NA NA NA NA 6291 FUN_035088 3197 1022 1857 3190 2638 ptg000025l:3612574-3650279 Q9H5I5 1.09e-24 Piezo-type mechanosensitive ion channel component 2 (Protein FAM38B) Homo sapiens (Human) cation transport [GO:0006812]; cellular response to mechanical stimulus [GO:0071260]; detection of mechanical stimulus [GO:0050982]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; regulation of membrane potential [GO:0042391]; response to mechanical stimulus [GO:0009612] GO:0005261; GO:0005886; GO:0006812; GO:0008381; GO:0009612; GO:0016020; GO:0042391; GO:0050974; GO:0050982; GO:0071260 6292 FUN_010993 13 0 0 24 16 NA NA NA NA NA NA NA 6293 FUN_015740 0 0 11 0 0 NA NA NA NA NA NA NA 6294 FUN_010991 6 0 0 0 0 NA NA NA NA NA NA NA 6295 FUN_033907 2337 2127 1369 2749 1464 NA NA NA NA NA NA NA 6296 FUN_033906 698 519 483 845 1316 NA NA NA NA NA NA NA 6297 FUN_033905 15 4 10 4 0 NA NA NA NA NA NA NA 6298 FUN_015742 90 41 32 0 37 NA NA NA NA NA NA NA 6299 FUN_010997 3683 2989 1683 2714 1343 NA NA NA NA NA NA NA 6300 FUN_033909 527 402 116 291 348 NA NA NA NA NA NA NA 6301 FUN_033908 2514 3235 740 1844 2664 NA NA NA NA NA NA NA 6302 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 3.39e-110 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6303 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 5.65e-106 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6304 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 6.08e-103 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6305 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 1.21e-63 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6306 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 3.07e-58 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6307 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 4.27e-33 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6308 FUN_018805 373 331 443 420 633 ptg000012l:13784096-13790641 Q5R5U3 1.4e-25 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 6309 FUN_018804 22 30 302 46 351 NA NA NA NA NA NA NA 6310 FUN_024888 0 32 117 39 59 ptg000018l:12205561-12232187 Q9U6Y5 2.25e-36 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 6311 FUN_024888 0 32 117 39 59 ptg000018l:12205561-12232187 Q9U6Y5 1.51e-35 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 6312 FUN_024888 0 32 117 39 59 ptg000018l:12205561-12232187 Q9U6Y5 1.92e-34 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 6313 FUN_024888 0 32 117 39 59 ptg000018l:12205561-12232187 Q9U6Y5 3.41e-34 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 6314 FUN_018801 0 0 0 6 0 NA NA NA NA NA NA NA 6315 FUN_018800 14 17 0 22 0 NA NA NA NA NA NA NA 6316 FUN_018803 0 0 0 0 28 NA NA NA NA NA NA NA 6317 FUN_018802 390 269 191 270 163 NA NA NA NA NA NA NA 6318 FUN_024882 86 133 33 50 64 NA NA NA NA NA NA NA 6319 FUN_024883 12 12 59 17 11 NA NA NA NA NA NA NA 6320 FUN_024881 3192 1906 475 2621 1057 ptg000018l:12056639-12057482 P52046 9.15e-29 Short-chain-enoyl-CoA hydratase (EC 4.2.1.150) (3-hydroxybutyryl-CoA dehydratase) (Crotonase) Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) butyrate metabolic process [GO:0019605] GO:0016829; GO:0019605 6321 FUN_024886 28 9 0 42 8 NA NA NA NA NA NA NA 6322 FUN_024884 0 0 6 0 10 NA NA NA NA NA NA NA 6323 FUN_024885 173 206 60 586 237 ptg000018l:12097379-12149406 M9NDE3 2.31e-26 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 6324 FUN_040133 1833 1442 913 2088 1065 NA NA NA NA NA NA NA 6325 FUN_016618 20 10 27 16 110 NA NA NA NA NA NA NA 6326 FUN_030288 3 0 5 0 20 ptg000023l:10536915-10537678 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6327 FUN_030284 5 0 4 1 20 ptg000023l:10528811-10529574 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6328 FUN_030286 4 0 7 0 22 ptg000023l:10532863-10533626 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6329 FUN_030280 6 0 6 0 21 ptg000023l:10520707-10521470 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6330 FUN_030282 3 0 5 0 22 ptg000023l:10524759-10525522 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6331 FUN_021105 0 0 0 0 74 NA NA NA NA NA NA NA 6332 FUN_021107 5717 3219 2635 4429 2436 ptg000016l:792952-846316 Q5ZMC3 4.75e-36 WD repeat, SAM and U-box domain-containing protein 1 Gallus gallus (Chicken) NA GO:0004842 6333 FUN_031736 2253 2538 744 1593 1219 NA NA NA NA NA NA NA 6334 FUN_021108 2949 3577 1206 2271 2089 ptg000016l:846617-887385 Q95SX7 1.67e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 6335 FUN_021109 5 3 0 1 6 NA NA NA NA NA NA NA 6336 FUN_031888 1117 671 314 490 438 NA NA NA NA NA NA NA 6337 FUN_016133 9 11 0 0 2 NA NA NA NA NA NA NA 6338 FUN_016132 242 397 155 311 347 ptg000010l:1958821-1959979 Q8N4B1 2.95e-37 Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1) Homo sapiens (Human) endosome organization [GO:0007032]; receptor recycling [GO:0001881]; retrograde transport, endosome to Golgi [GO:0042147] GO:0001881; GO:0005769; GO:0005802; GO:0005829; GO:0007032; GO:0030136; GO:0042147; GO:0042803; GO:0055037 6339 FUN_031880 0 0 13 0 0 NA NA NA NA NA NA NA 6340 FUN_031881 32 0 0 0 0 NA NA NA NA NA NA NA 6341 FUN_031882 30 0 53 171 67 ptg000023l:26428033-26436902 Q9W0Y8 6.68e-84 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 6342 FUN_031882 30 0 53 171 67 ptg000023l:26428033-26436902 Q9W0Y8 2.49e-28 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 6343 FUN_031883 16 0 16 0 6 NA NA NA NA NA NA NA 6344 FUN_031884 9 0 0 13 0 NA NA NA NA NA NA NA 6345 FUN_031886 45 10 22 45 0 NA NA NA NA NA NA NA 6346 FUN_031887 557 319 104 266 244 NA NA NA NA NA NA NA 6347 FUN_042210 0 0 5 2 17 NA NA NA NA NA NA NA 6348 FUN_042217 4 0 0 0 13 NA NA NA NA NA NA NA 6349 FUN_030429 9 0 10 0 38 ptg000023l:10850012-10850775 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6350 FUN_043373 248 158 111 274 291 ptg000047l:7683971-7685063 P69478 4.15e-42 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 6351 FUN_002600 47 0 16 0 95 NA NA NA NA NA NA NA 6352 FUN_035418 1907 3934 2177 5858 4098 NA NA NA NA NA NA NA 6353 FUN_035417 338 160 129 351 212 NA NA NA NA NA NA NA 6354 FUN_030423 12 0 9 0 35 ptg000023l:10834412-10835175 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6355 FUN_016134 82 46 11 44 69 NA NA NA NA NA NA NA 6356 FUN_030425 0 0 0 0 7 ptg000023l:10840411-10842671 P84239 7.08e-87 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6357 FUN_035412 21 0 34 345 116 ptg000025l:7174663-7185587 Q9BVG8 1.05e-21 Kinesin-like protein KIFC3 Homo sapiens (Human) epithelial cell-cell adhesion [GO:0090136]; Golgi organization [GO:0007030]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017]; visual perception [GO:0007601]; zonula adherens maintenance [GO:0045218] GO:0003777; GO:0005524; GO:0005794; GO:0005813; GO:0005871; GO:0005874; GO:0005915; GO:0007017; GO:0007018; GO:0007030; GO:0007601; GO:0008017; GO:0015630; GO:0030659; GO:0042802; GO:0045218; GO:0070062; GO:0090136 6358 FUN_030427 11 0 12 0 32 ptg000023l:10845960-10846723 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6359 FUN_038638 1271 575 369 325 531 NA NA NA NA NA NA NA 6360 FUN_038639 20 0 0 0 0 ptg000027l:9600053-9604503 Q1LYL8 8.11e-32 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 6361 FUN_004959 0 0 16 0 4 NA NA NA NA NA NA NA 6362 FUN_038634 2738 2260 1917 3479 2127 ptg000027l:9525294-9548276 Q7ZXX2 2.74e-23 Kinesin-like protein KIF19 Xenopus laevis (African clawed frog) axonemal microtubule depolymerization [GO:0060404]; microtubule-based movement [GO:0007018]; plus-end specific microtubule depolymerization [GO:0070462] GO:0005524; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008017; GO:0008574; GO:0060404; GO:0070462 6363 FUN_004954 0 0 0 7 5 NA NA NA NA NA NA NA 6364 FUN_038630 216 387 65 278 166 NA NA NA NA NA NA NA 6365 FUN_016139 514 201 328 415 637 NA NA NA NA NA NA NA 6366 FUN_004950 21 0 35 0 88 NA NA NA NA NA NA NA 6367 FUN_038633 370 546 555 378 399 ptg000027l:9519580-9523458 Q5EAE5 2.05e-25 Josephin-1 (EC 3.4.19.12) (Josephin domain-containing protein 1) Bos taurus (Bovine) protein deubiquitination [GO:0016579] GO:0004843; GO:0005737; GO:0005886; GO:0016579 6368 FUN_016138 178 177 110 172 146 ptg000010l:2005169-2006333 Q8IV77 1.73e-55 Cyclic nucleotide-gated cation channel alpha-4 (Cyclic nucleotide-gated channel alpha-4) (CNG channel alpha-4) (CNG-4) (CNG4) Homo sapiens (Human) cation transmembrane transport [GO:0098655]; response to stimulus [GO:0050896]; sensory perception of smell [GO:0007608] GO:0005222; GO:0005223; GO:0005886; GO:0007608; GO:0017071; GO:0030552; GO:0030553; GO:0030660; GO:0044877; GO:0050896; GO:0060170; GO:0098655 6369 FUN_002601 107 1464 445 5331 9 NA NA NA NA NA NA NA 6370 FUN_008334 4 17 16 13 2 NA NA NA NA NA NA NA 6371 FUN_010170 42 0 0 0 0 NA NA NA NA NA NA NA 6372 FUN_010746 5350 5809 2983 3420 2129 NA NA NA NA NA NA NA 6373 FUN_020767 0 0 0 260 67 NA NA NA NA NA NA NA 6374 FUN_020765 0 0 0 0 12 NA NA NA NA NA NA NA 6375 FUN_020763 0 0 0 0 8 NA NA NA NA NA NA NA 6376 FUN_015996 152 130 146 96 78 NA NA NA NA NA NA NA 6377 FUN_010745 4796 2237 1518 3886 4588 NA NA NA NA NA NA NA 6378 FUN_015990 409 68 130 168 84 ptg000010l:202381-207077 F6QEU4 1.98e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 6379 FUN_015991 6812 3281 1092 2617 725 NA NA NA NA NA NA NA 6380 FUN_015992 4080 23 6 2443 17 NA NA NA NA NA NA NA 6381 FUN_015993 299 54 38 85 55 ptg000010l:224102-226007 Q08AE8 3.67e-48 Protein spire homolog 1 (Spir-1) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament network formation [GO:0051639]; actin filament polymerization [GO:0030041]; actin nucleation [GO:0045010]; cleavage furrow formation [GO:0036089]; establishment of meiotic spindle localization [GO:0051295]; formin-nucleated actin cable assembly [GO:0070649]; Golgi vesicle transport [GO:0048193]; innate immune response [GO:0045087]; intracellular transport [GO:0046907]; polar body extrusion after meiotic divisions [GO:0040038]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of mitochondrial fission [GO:0090141]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0003779; GO:0005654; GO:0005741; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0015031; GO:0016192; GO:0030036; GO:0030041; GO:0030659; GO:0036089; GO:0040038; GO:0045010; GO:0045087; GO:0046907; GO:0048193; GO:0048471; GO:0051295; GO:0051639; GO:0070649; GO:0090141; GO:2000781 6382 FUN_016761 32 14 405 68 244 ptg000011l:7124211-7144639 S8FIE4 2.17e-53 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 6383 FUN_036148 31959 22569 13761 27154 24315 ptg000025l:15707964-15711592 P18700 1.58e-110 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 6384 FUN_036148 31959 22569 13761 27154 24315 ptg000025l:15707964-15711592 P18700 5.81e-54 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 6385 FUN_036149 1181 1367 957 1170 1015 ptg000025l:15711848-15719659 Q503C8 5.89e-32 NudC domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737 6386 FUN_036144 795 1132 525 859 817 ptg000025l:15685397-15687178 P41386 2.53e-88 Tubulin beta chain (Beta-tubulin) Haliotis discus (Abalone) (Nordotis discus) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017 6387 FUN_036145 30489 21514 14607 19488 15200 ptg000025l:15689909-15693350 P32882 2.07e-114 Tubulin beta-2 chain (Beta-tubulin class-II) Gallus gallus (Chicken) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of microtubule polymerization [GO:0031115] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005509; GO:0005525; GO:0005737; GO:0005874; GO:0031115 6388 FUN_036145 30489 21514 14607 19488 15200 ptg000025l:15689909-15693350 P32882 2.07e-114 Tubulin beta-2 chain (Beta-tubulin class-II) Gallus gallus (Chicken) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of microtubule polymerization [GO:0031115] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005509; GO:0005525; GO:0005737; GO:0005874; GO:0031115 6389 FUN_036145 30489 21514 14607 19488 15200 ptg000025l:15689909-15693350 P32882 2.07e-114 Tubulin beta-2 chain (Beta-tubulin class-II) Gallus gallus (Chicken) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of microtubule polymerization [GO:0031115] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005509; GO:0005525; GO:0005737; GO:0005874; GO:0031115 6390 FUN_036145 30489 21514 14607 19488 15200 ptg000025l:15689909-15693350 P32882 4.05e-108 Tubulin beta-2 chain (Beta-tubulin class-II) Gallus gallus (Chicken) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278]; negative regulation of microtubule polymerization [GO:0031115] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005509; GO:0005525; GO:0005737; GO:0005874; GO:0031115 6391 FUN_036146 9132 10448 4701 9081 10041 ptg000025l:15695260-15698262 P18700 1.84e-111 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 6392 FUN_036147 157 1247 1184 1205 1444 ptg000025l:15699407-15700046 P36221 6.98e-76 Tubulin beta-1 chain (Beta-1-tubulin) Notothenia neglecta (Yellowbelly rockcod) (Notothenia coriiceps neglecta) microtubule-based process [GO:0007017] GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0046872 6393 FUN_036143 334 273 40 272 95 ptg000025l:15677553-15683248 P18700 4.47e-78 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 6394 FUN_036143 334 273 40 272 95 ptg000025l:15677553-15683248 P18700 2.1e-39 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 6395 FUN_037811 142 26 49 112 40 NA NA NA NA NA NA NA 6396 FUN_037810 1177 565 708 1586 916 NA NA NA NA NA NA NA 6397 FUN_037813 179 54 37 110 76 ptg000026l:13983756-13990688 Q28CH3 1.47e-31 UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0070569 6398 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 0 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6399 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.09e-94 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6400 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.02e-89 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6401 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.42e-78 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6402 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.42e-78 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6403 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.09e-60 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6404 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.9e-59 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6405 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.91e-55 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6406 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.11e-54 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6407 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.74e-52 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6408 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.03e-50 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6409 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.63e-47 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6410 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.59e-47 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6411 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.72e-47 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6412 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.28e-46 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6413 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.73e-46 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6414 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 8.52e-46 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6415 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1e-44 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6416 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.02e-44 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6417 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.08e-43 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6418 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.41e-43 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6419 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.77e-43 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6420 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.65e-43 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6421 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.68e-43 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6422 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.67e-42 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6423 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.17e-42 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6424 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.07e-41 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6425 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.62e-41 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6426 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.14e-41 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6427 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.02e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6428 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.19e-40 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6429 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.87e-39 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6430 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.79e-39 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6431 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.96e-39 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6432 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.64e-39 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6433 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.43e-38 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6434 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.89e-38 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6435 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.21e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6436 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.42e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6437 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.64e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6438 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.99e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6439 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.25e-37 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6440 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.03e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6441 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.88e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6442 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.1e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6443 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.8e-36 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6444 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.48e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6445 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.27e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6446 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.71e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6447 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.91e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6448 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.37e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6449 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.37e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6450 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 8.52e-35 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6451 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.86e-34 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6452 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.09e-34 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6453 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.94e-34 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6454 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.17e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6455 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.85e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6456 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.82e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6457 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.82e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6458 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.86e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6459 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.86e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6460 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.64e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6461 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 8.31e-33 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6462 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.16e-32 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6463 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.61e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6464 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.21e-31 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6465 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.11e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6466 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.27e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6467 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.72e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6468 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.27e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6469 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.47e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6470 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.54e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6471 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.54e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6472 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.5e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6473 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.95e-30 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6474 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.54e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6475 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.08e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6476 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.17e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6477 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.17e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6478 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.65e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6479 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.5e-29 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6480 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.67e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6481 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.67e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6482 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.72e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6483 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.29e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6484 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.21e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6485 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.21e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6486 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.79e-28 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6487 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.07e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6488 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.83e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6489 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.99e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6490 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.99e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6491 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.08e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6492 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 6.31e-27 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6493 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.99e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6494 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.32e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6495 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.08e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6496 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.08e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6497 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.27e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6498 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 8.64e-26 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6499 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.67e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6500 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.34e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6501 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.34e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6502 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.91e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6503 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 8.67e-25 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6504 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.05e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6505 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.33e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6506 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.04e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6507 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6508 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.05e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6509 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.05e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6510 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.55e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6511 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.88e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6512 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.47e-24 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6513 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6514 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.88e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6515 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.03e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6516 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.03e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6517 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.6e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6518 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.63e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6519 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.74e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6520 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.52e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6521 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.16e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6522 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.34e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6523 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.48e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6524 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.53e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6525 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.78e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6526 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.91e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6527 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.27e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6528 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.27e-23 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6529 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.39e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6530 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.47e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6531 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.72e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6532 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.51e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6533 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.51e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6534 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.65e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6535 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 5.1e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6536 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.43e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6537 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.88e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6538 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.95e-22 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6539 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.33e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6540 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.66e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6541 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.66e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6542 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 1.67e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6543 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.04e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6544 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.42e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6545 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.42e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6546 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 2.46e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6547 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.92e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6548 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 3.99e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6549 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 4.75e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6550 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.04e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6551 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 7.53e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6552 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.2e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6553 FUN_037812 25031 10288 37169 42154 26232 ptg000026l:13848976-13967201 B3EWZ5 9.75e-21 MAM and LDL-receptor class A domain-containing protein 1 (Skeletal organic matrix MAM and LDL-receptor 1) (SOM MAM and LDL-receptor 1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 6554 FUN_037815 1956 684 516 2182 641 NA NA NA NA NA NA NA 6555 FUN_037814 92 91 0 1 40 ptg000026l:14004516-14004999 Q91YN5 3.27e-30 UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)] Mus musculus (Mouse) UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0003977; GO:0005654; GO:0005829; GO:0005886; GO:0006047; GO:0006048; GO:0030246; GO:0042802; GO:0052630 6556 FUN_037816 0 0 4 45 19 NA NA NA NA NA NA NA 6557 FUN_037819 240 308 184 559 417 NA NA NA NA NA NA NA 6558 FUN_037818 174 224 288 315 259 NA NA NA NA NA NA NA 6559 FUN_000127 2 1 7 0 13 ntLink_4:186279-187042 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6560 FUN_005333 1120 805 461 828 823 NA NA NA NA NA NA NA 6561 FUN_005332 158 106 189 82 114 ntLink_8:34094381-34100005 A0JN62 4.21e-22 Centrosomal protein of 120 kDa (Cep120) (Coiled-coil domain-containing protein 100) Bos taurus (Bovine) astral microtubule organization [GO:0030953]; centrosome cycle [GO:0007098]; cerebral cortex development [GO:0021987]; interkinetic nuclear migration [GO:0022027]; neurogenesis [GO:0022008]; positive regulation of centriole elongation [GO:1903724]; positive regulation of centrosome duplication [GO:0010825]; positive regulation of cilium assembly [GO:0045724]; positive regulation of establishment of protein localization [GO:1904951] GO:0005737; GO:0005813; GO:0005814; GO:0007098; GO:0008022; GO:0010825; GO:0021987; GO:0022008; GO:0022027; GO:0030953; GO:0045724; GO:1903724; GO:1904951 6562 FUN_005335 3433 2801 2264 3106 3012 NA NA NA NA NA NA NA 6563 FUN_000122 10 3 21 3 37 ntLink_4:175566-177881 P35061 6.65e-78 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6564 FUN_000121 4 0 3 0 14 ntLink_4:169645-170426 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6565 FUN_005339 781 652 641 570 563 ntLink_8:34205027-34207053 Q9H1A7 1.03e-28 DNA-directed RNA polymerase II subunit RPB11-b2 (RNA polymerase II subunit B11-b2) (RPB11b2) (DNA-directed RNA polymerase II subunit J3) Homo sapiens (Human) NA GO:0001055; GO:0003677; GO:0005665; GO:0046983 6566 FUN_005338 1149 1339 287 852 1382 NA NA NA NA NA NA NA 6567 FUN_000129 3 0 8 0 16 ntLink_4:190345-191108 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6568 FUN_007791 529 206 340 179 549 ptg000002l:4814038-4824612 Q9UHC1 5.38e-88 DNA mismatch repair protein Mlh3 (MutL protein homolog 3) Homo sapiens (Human) female meiosis I [GO:0007144]; male meiotic nuclear division [GO:0007140]; mismatch repair [GO:0006298]; protein localization [GO:0008104]; reciprocal meiotic recombination [GO:0007131]; synaptonemal complex assembly [GO:0007130] GO:0000795; GO:0001673; GO:0003682; GO:0003696; GO:0005524; GO:0005634; GO:0005654; GO:0005712; GO:0006298; GO:0007130; GO:0007131; GO:0007140; GO:0007144; GO:0008104; GO:0016887; GO:0019237; GO:0030983; GO:0032300; GO:0140664 6569 FUN_007790 1460 848 674 928 917 NA NA NA NA NA NA NA 6570 FUN_007793 54 37 23 142 31 NA NA NA NA NA NA NA 6571 FUN_007792 513 281 208 223 223 NA NA NA NA NA NA NA 6572 FUN_007795 1995 1070 1312 2163 2220 NA NA NA NA NA NA NA 6573 FUN_007794 630 503 454 933 573 ptg000002l:4847658-4849083 O88738 2.02e-40 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Mus musculus (Mouse) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; placenta development [GO:0001890]; positive regulation of cell population proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0001890; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 6574 FUN_007794 630 503 454 933 573 ptg000002l:4847658-4849083 O88738 1.31e-31 Baculoviral IAP repeat-containing protein 6 (EC 2.3.2.27) (BIR repeat-containing ubiquitin-conjugating enzyme) (BRUCE) (RING-type E3 ubiquitin transferase BIRC6) (Ubiquitin-conjugating BIR domain enzyme apollon) (APOLLON) Mus musculus (Mouse) apoptotic process [GO:0006915]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; labyrinthine layer development [GO:0060711]; negative regulation of apoptotic process [GO:0043066]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of peptidase activity [GO:0010466]; placenta development [GO:0001890]; positive regulation of cell population proliferation [GO:0008284]; protein ubiquitination [GO:0016567]; regulation of cell population proliferation [GO:0042127]; regulation of cytokinesis [GO:0032465]; spongiotrophoblast layer development [GO:0060712] GO:0000922; GO:0001890; GO:0004842; GO:0004869; GO:0005634; GO:0005768; GO:0005802; GO:0005815; GO:0006915; GO:0007049; GO:0008283; GO:0008284; GO:0010466; GO:0016020; GO:0016567; GO:0030496; GO:0032465; GO:0042127; GO:0043066; GO:0051301; GO:0060711; GO:0060712; GO:0061631; GO:0090543; GO:2001237 6575 FUN_007797 1725 1181 533 1001 530 NA NA NA NA NA NA NA 6576 FUN_007796 87 45 71 25 122 NA NA NA NA NA NA NA 6577 FUN_007799 357 302 142 144 181 NA NA NA NA NA NA NA 6578 FUN_007798 2197 1754 1321 2032 1210 ptg000002l:4898456-4901019 A7MB28 1.23e-35 Protein NDRG3 (N-myc downstream-regulated gene 3 protein) Bos taurus (Bovine) signal transduction [GO:0007165] GO:0005737; GO:0007165 6579 FUN_007798 2197 1754 1321 2032 1210 ptg000002l:4898456-4901019 A7MB28 2.93e-24 Protein NDRG3 (N-myc downstream-regulated gene 3 protein) Bos taurus (Bovine) signal transduction [GO:0007165] GO:0005737; GO:0007165 6580 FUN_034346 350 337 201 483 236 NA NA NA NA NA NA NA 6581 FUN_018316 427 274 514 785 1613 NA NA NA NA NA NA NA 6582 FUN_027238 0 0 70 10 141 NA NA NA NA NA NA NA 6583 FUN_012671 3196 3179 1367 2972 2287 NA NA NA NA NA NA NA 6584 FUN_027234 1118 297 393 579 198 NA NA NA NA NA NA NA 6585 FUN_027235 189 44 19 192 0 NA NA NA NA NA NA NA 6586 FUN_027236 21 51 65 65 137 NA NA NA NA NA NA NA 6587 FUN_027230 547 104 172 549 263 NA NA NA NA NA NA NA 6588 FUN_027231 29 0 17 6 32 NA NA NA NA NA NA NA 6589 FUN_027232 0 15 0 17 9 NA NA NA NA NA NA NA 6590 FUN_031672 1020 256 379 824 673 NA NA NA NA NA NA NA 6591 FUN_012673 93 139 86 226 86 NA NA NA NA NA NA NA 6592 FUN_018313 683 426 409 487 1309 NA NA NA NA NA NA NA 6593 FUN_012674 2456 4379 2057 4832 3008 NA NA NA NA NA NA NA 6594 FUN_043603 36616 46957 16958 19127 15518 NA NA NA NA NA NA NA 6595 FUN_018312 4380 457 1854 1175 966 NA NA NA NA NA NA NA 6596 FUN_017283 0 6 0 0 16 NA NA NA NA NA NA NA 6597 FUN_018319 228 0 148 546 84 NA NA NA NA NA NA NA 6598 FUN_008310 119 104 86 85 194 NA NA NA NA NA NA NA 6599 FUN_008311 106 13 0 36 65 NA NA NA NA NA NA NA 6600 FUN_008312 0 0 0 0 19 NA NA NA NA NA NA NA 6601 FUN_008313 325 279 183 267 464 NA NA NA NA NA NA NA 6602 FUN_008314 50637 34618 15717 38440 37491 NA NA NA NA NA NA NA 6603 FUN_008315 955 51 346 808 45 NA NA NA NA NA NA NA 6604 FUN_008316 638 25 283 439 27 NA NA NA NA NA NA NA 6605 FUN_008317 33 28 0 0 0 NA NA NA NA NA NA NA 6606 FUN_008319 23 0 0 14 78 NA NA NA NA NA NA NA 6607 FUN_005189 2723 3305 1252 3507 2266 NA NA NA NA NA NA NA 6608 FUN_016959 147 28 4 145 17 ptg000011l:9402652-9409057 Q96AY4 9.54e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6609 FUN_016959 147 28 4 145 17 ptg000011l:9402652-9409057 Q96AY4 1.22e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6610 FUN_016959 147 28 4 145 17 ptg000011l:9402652-9409057 Q96AY4 7.69e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6611 FUN_016959 147 28 4 145 17 ptg000011l:9402652-9409057 Q96AY4 3.97e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6612 FUN_016957 102 60 21 189 56 NA NA NA NA NA NA NA 6613 FUN_016950 26 74 119 244 219 NA NA NA NA NA NA NA 6614 FUN_016952 37 0 0 0 0 NA NA NA NA NA NA NA 6615 FUN_003474 33 157 18 90 208 NA NA NA NA NA NA NA 6616 FUN_003477 3612 1735 2991 6155 8291 NA NA NA NA NA NA NA 6617 FUN_003471 96 351 44 131 270 NA NA NA NA NA NA NA 6618 FUN_003472 0 19 0 15 17 NA NA NA NA NA NA NA 6619 FUN_003473 38 148 15 60 123 NA NA NA NA NA NA NA 6620 FUN_003478 261 1551 1101 1574 1080 NA NA NA NA NA NA NA 6621 FUN_003479 101 30 22 42 128 NA NA NA NA NA NA NA 6622 FUN_014503 514 367 302 663 502 NA NA NA NA NA NA NA 6623 FUN_006446 38 112 76 21 72 NA NA NA NA NA NA NA 6624 FUN_006447 330 176 181 168 326 NA NA NA NA NA NA NA 6625 FUN_006444 642 255 303 639 543 ptg000001l:12484615-12486071 Q8IVH4 5.67e-50 Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0009235; GO:0042802; GO:0042803 6626 FUN_006444 642 255 303 639 543 ptg000001l:12484615-12486071 Q8IVH4 1.39e-40 Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0009235; GO:0042802; GO:0042803 6627 FUN_006445 6 35 0 18 21 NA NA NA NA NA NA NA 6628 FUN_006442 1759 1126 777 1244 1300 NA NA NA NA NA NA NA 6629 FUN_006443 281 152 140 306 418 ptg000001l:12484039-12484477 Q8IVH4 1.33e-22 Methylmalonic aciduria type A protein, mitochondrial (EC 3.6.-.-) Homo sapiens (Human) cobalamin metabolic process [GO:0009235] GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0005829; GO:0009235; GO:0042802; GO:0042803 6630 FUN_006440 450 236 219 884 229 NA NA NA NA NA NA NA 6631 FUN_006441 1469 1254 769 1265 1036 NA NA NA NA NA NA NA 6632 FUN_006448 992 662 456 669 348 NA NA NA NA NA NA NA 6633 FUN_006449 821 1053 635 1585 778 NA NA NA NA NA NA NA 6634 FUN_004178 24 0 11 0 37 NA NA NA NA NA NA NA 6635 FUN_004179 0 40 23 33 11 NA NA NA NA NA NA NA 6636 FUN_003788 569 9 31 392 531 NA NA NA NA NA NA NA 6637 FUN_003789 176 170 54 76 109 NA NA NA NA NA NA NA 6638 FUN_003786 280 85 33616 260 57 NA NA NA NA NA NA NA 6639 FUN_003787 36 34 19 3 5 NA NA NA NA NA NA NA 6640 FUN_004172 6145 5015 3515 5921 3908 NA NA NA NA NA NA NA 6641 FUN_004173 32 9 28 53 13 NA NA NA NA NA NA NA 6642 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 2.63e-36 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6643 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 3.33e-33 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6644 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 7.39e-26 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6645 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 1.76e-24 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6646 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 5.16e-24 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6647 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 7.03e-24 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6648 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 1.08e-23 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6649 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 1.4e-23 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6650 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 1.29e-22 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6651 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 4.78e-22 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6652 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 2.74e-21 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6653 FUN_004174 2440 1442 2456 6675 3198 ntLink_8:20158663-20340468 A4IFW2 7.74e-21 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) Danio rerio (Zebrafish) (Brachydanio rerio) peptidyl-tyrosine dephosphorylation [GO:0035335]; protein dephosphorylation [GO:0006470]; sensory neuron axon guidance [GO:0097374]; synaptic membrane adhesion [GO:0099560] GO:0004725; GO:0006470; GO:0008201; GO:0016020; GO:0035335; GO:0097374; GO:0099560 6654 FUN_003783 11 0 33 7 12 NA NA NA NA NA NA NA 6655 FUN_004176 1250 750 351 574 456 NA NA NA NA NA NA NA 6656 FUN_026545 149 102 89 70 36 ptg000020l:10334946-10335348 Q7ZSX3 3.18e-35 Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) Danio rerio (Zebrafish) (Brachydanio rerio) amacrine cell differentiation [GO:0035881]; animal organ morphogenesis [GO:0009887]; cell differentiation [GO:0030154]; developmental process [GO:0032502]; exocrine pancreas development [GO:0031017]; generation of neurons [GO:0048699]; hindbrain development [GO:0030902]; pancreas development [GO:0031016]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; tissue development [GO:0009888] GO:0000977; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0005737; GO:0006355; GO:0006357; GO:0009887; GO:0009888; GO:0030154; GO:0030902; GO:0031016; GO:0031017; GO:0032502; GO:0035881; GO:0043565; GO:0045893; GO:0046983; GO:0048384; GO:0048699 6657 FUN_026544 3 2 7 16 19 NA NA NA NA NA NA NA 6658 FUN_026547 411 466 372 120 53 NA NA NA NA NA NA NA 6659 FUN_043602 8488 6942 2819 11331 3697 NA NA NA NA NA NA NA 6660 FUN_034733 16 0 26 7 20 NA NA NA NA NA NA NA 6661 FUN_034735 0 21 3 19 3 NA NA NA NA NA NA NA 6662 FUN_015988 494 547 641 893 440 NA NA NA NA NA NA NA 6663 FUN_034739 5 0 7 2 6 NA NA NA NA NA NA NA 6664 FUN_034738 1803 2520 880 804 1350 NA NA NA NA NA NA NA 6665 FUN_005185 4537 2721 2580 4292 3359 ntLink_8:32336148-32364675 P30205 5.78e-28 Antigen WC1.1 Bos taurus (Bovine) NA GO:0005044; GO:0005576; GO:0009897 6666 FUN_026542 1014 740 651 824 1066 ptg000020l:10291297-10296483 Q8BHN5 1.22e-60 RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) Mus musculus (Mouse) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0007399; GO:0030154; GO:0042802; GO:1990904 6667 FUN_022049 2216 3471 1864 5973 2994 ptg000016l:5050517-5054136 Q9C098 3.01e-52 Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0018105; GO:0106310 6668 FUN_022049 2216 3471 1864 5973 2994 ptg000016l:5050517-5054136 Q9C098 4.64e-37 Serine/threonine-protein kinase DCLK3 (EC 2.7.11.1) (Doublecortin domain-containing protein 3C) (Doublecortin-like and CAM kinase-like 3) (Doublecortin-like kinase 3) Homo sapiens (Human) peptidyl-serine phosphorylation [GO:0018105] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0018105; GO:0106310 6669 FUN_004813 0 11 0 0 0 ntLink_8:27287773-27294596 Q54T82 1.02e-24 Putative leucine-rich repeat-containing protein DDB_G0281931 Dictyostelium discoideum (Social amoeba) NA GO:0016020 6670 FUN_031471 684 574 330 342 381 NA NA NA NA NA NA NA 6671 FUN_022046 2125 1022 812 1527 1445 NA NA NA NA NA NA NA 6672 FUN_031470 1648 693 812 2235 1889 ptg000023l:21824383-21841055 Q9JLC8 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 6673 FUN_031470 1648 693 812 2235 1889 ptg000023l:21824383-21841055 Q9JLC8 2.19e-47 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 6674 FUN_031470 1648 693 812 2235 1889 ptg000023l:21824383-21841055 Q9JLC8 6.07e-38 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 6675 FUN_031470 1648 693 812 2235 1889 ptg000023l:21824383-21841055 Q9JLC8 4.88e-24 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 6676 FUN_022047 5862 7393 6496 12769 9213 NA NA NA NA NA NA NA 6677 FUN_011729 1582 765 801 1014 989 NA NA NA NA NA NA NA 6678 FUN_011728 1245 859 493 1264 307 NA NA NA NA NA NA NA 6679 FUN_002439 5 29 123 0 34 NA NA NA NA NA NA NA 6680 FUN_002438 128 0 0 185 199 NA NA NA NA NA NA NA 6681 FUN_002437 0 0 55 7 48 NA NA NA NA NA NA NA 6682 FUN_011722 14 0 0 0 16 NA NA NA NA NA NA NA 6683 FUN_011721 7067 2126 2055 4271 697 NA NA NA NA NA NA NA 6684 FUN_002434 1397 238 134 574 16 NA NA NA NA NA NA NA 6685 FUN_002433 752 351 293 594 694 ntLink_8:1537514-1543906 F1LU71 1.19e-26 Methylglutaconyl-CoA hydratase, mitochondrial (3-MG-CoA hydratase) (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (Itaconyl-CoA hydratase) (EC 4.2.1.56) Rattus norvegicus (Rat) fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552] GO:0003723; GO:0003730; GO:0004300; GO:0004490; GO:0005739; GO:0006552; GO:0006635; GO:0050011 6686 FUN_002433 752 351 293 594 694 ntLink_8:1537514-1543906 F1LU71 4.67e-21 Methylglutaconyl-CoA hydratase, mitochondrial (3-MG-CoA hydratase) (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (Itaconyl-CoA hydratase) (EC 4.2.1.56) Rattus norvegicus (Rat) fatty acid beta-oxidation [GO:0006635]; leucine catabolic process [GO:0006552] GO:0003723; GO:0003730; GO:0004300; GO:0004490; GO:0005739; GO:0006552; GO:0006635; GO:0050011 6687 FUN_011726 497 343 200 418 488 ptg000008l:631054-631855 Q6GNS1 1.62e-31 Carbohydrate sulfotransferase 10 (EC 2.8.2.-) (HNK-1 sulfotransferase) (HNK-1ST) (HNK1ST) Xenopus laevis (African clawed frog) carbohydrate biosynthetic process [GO:0016051] GO:0000139; GO:0008146; GO:0016051 6688 FUN_011725 516 155 141 370 211 NA NA NA NA NA NA NA 6689 FUN_011724 358 201 144 338 251 NA NA NA NA NA NA NA 6690 FUN_000462 220 240 212 1456 1123 NA NA NA NA NA NA NA 6691 FUN_000463 5 11 0 4 5 NA NA NA NA NA NA NA 6692 FUN_000460 899 450 351 660 412 NA NA NA NA NA NA NA 6693 FUN_000461 11 300 199 567 549 NA NA NA NA NA NA NA 6694 FUN_000466 4774 2934 3036 5666 6086 NA NA NA NA NA NA NA 6695 FUN_000467 3923 3129 1836 3806 1991 NA NA NA NA NA NA NA 6696 FUN_000464 0 30 56 63 272 NA NA NA NA NA NA NA 6697 FUN_000465 232 185 258 369 937 NA NA NA NA NA NA NA 6698 FUN_000468 2168 1472 624 1980 1069 NA NA NA NA NA NA NA 6699 FUN_000469 282 517 127 190 157 NA NA NA NA NA NA NA 6700 FUN_029351 5 0 0 6 1 NA NA NA NA NA NA NA 6701 FUN_029350 15 5 15 0 4 NA NA NA NA NA NA NA 6702 FUN_029353 0 0 0 2 10 NA NA NA NA NA NA NA 6703 FUN_029352 21 47 11 9 31 NA NA NA NA NA NA NA 6704 FUN_029355 234 123 19 274 242 NA NA NA NA NA NA NA 6705 FUN_029354 0 0 0 0 9 NA NA NA NA NA NA NA 6706 FUN_029357 1063 924 694 984 863 ptg000023l:949591-953293 Q9UIJ7 1.31e-24 GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (Adenylate kinase 3 alpha-like 1) Homo sapiens (Human) ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; blood coagulation [GO:0007596]; GTP metabolic process [GO:0046039]; ITP metabolic process [GO:0046041]; nucleoside triphosphate biosynthetic process [GO:0009142]; phosphorylation [GO:0016310]; UTP metabolic process [GO:0046051] GO:0005524; GO:0005525; GO:0005737; GO:0005739; GO:0005759; GO:0006172; GO:0007596; GO:0009142; GO:0016310; GO:0046033; GO:0046039; GO:0046041; GO:0046051; GO:0046899 6707 FUN_029356 730 478 630 920 1263 ptg000023l:934190-948604 Q03650 1.55e-38 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 6708 FUN_029356 730 478 630 920 1263 ptg000023l:934190-948604 Q03650 1.66e-38 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 6709 FUN_029356 730 478 630 920 1263 ptg000023l:934190-948604 Q03650 2.72e-38 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 6710 FUN_029356 730 478 630 920 1263 ptg000023l:934190-948604 Q03650 1.48e-31 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 6711 FUN_029356 730 478 630 920 1263 ptg000023l:934190-948604 Q03650 3e-28 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 6712 FUN_029359 428 177 309 244 398 NA NA NA NA NA NA NA 6713 FUN_029358 90 35 19 103 57 ptg000023l:959320-961453 O93403 7.78e-25 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 6714 FUN_029689 7 0 0 0 30 NA NA NA NA NA NA NA 6715 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 4.34e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6716 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 1.06e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6717 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 2.33e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6718 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 1.18e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6719 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 3.58e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6720 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 8.29e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6721 FUN_029688 186 25 38 56 79 ptg000023l:4534150-4541622 Q96AY4 2.66e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6722 FUN_029683 0 0 0 0 7 NA NA NA NA NA NA NA 6723 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 4.58e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6724 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 1.68e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6725 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 7.14e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6726 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 1.2e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6727 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 1.14e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6728 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 6.32e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6729 FUN_029682 107 2 95 52 66 ptg000023l:4465466-4472953 Q96AY4 2.74e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6730 FUN_029681 205 0 8 18 58 ptg000023l:4451022-4456758 F6QEU4 7.75e-22 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 6731 FUN_029680 960 494 148 792 160 ptg000023l:4434652-4436250 Q1PSW8 2.18e-33 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 6732 FUN_029687 87 37 23 21 11 ptg000023l:4522649-4524868 E7FAM5 1.89e-50 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 6733 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 2.23e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6734 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 2.22e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6735 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 3.43e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6736 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 5.49e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6737 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 1.14e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6738 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 3.46e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6739 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 7.68e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6740 FUN_029686 121 6 128 73 0 ptg000023l:4506818-4520134 Q96AY4 6.63e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 6741 FUN_029685 0 23 0 0 4 NA NA NA NA NA NA NA 6742 FUN_029684 13 0 0 0 14 ptg000023l:4480911-4483218 D2GXS7 7.87e-27 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Ailuropoda melanoleuca (Giant panda) regulation of neuron apoptotic process [GO:0043523] GO:0004842; GO:0005737; GO:0008270; GO:0043523 6743 FUN_013478 0 43 6 42 0 ptg000008l:23140241-23140949 Q99570 5.15e-26 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 6744 FUN_013475 12 19 0 2 14 NA NA NA NA NA NA NA 6745 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 4.42e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6746 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 4.07e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6747 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 7.74e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6748 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 1.45e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6749 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 1.77e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6750 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 6.7e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6751 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 9.62e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6752 FUN_013474 110 306 112 903 12 ptg000008l:23056757-23069758 Q7RTR2 8.51e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6753 FUN_013477 434 380 283 688 314 ptg000008l:23109441-23117968 Q7RTR2 3.53e-76 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6754 FUN_013477 434 380 283 688 314 ptg000008l:23109441-23117968 Q7RTR2 2.47e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6755 FUN_013477 434 380 283 688 314 ptg000008l:23109441-23117968 Q7RTR2 8.85e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6756 FUN_013477 434 380 283 688 314 ptg000008l:23109441-23117968 Q7RTR2 6.41e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6757 FUN_013477 434 380 283 688 314 ptg000008l:23109441-23117968 Q7RTR2 1.34e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6758 FUN_013477 434 380 283 688 314 ptg000008l:23109441-23117968 Q7RTR2 6.04e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6759 FUN_013470 0 139 0 24 0 NA NA NA NA NA NA NA 6760 FUN_013473 48 54 40 74 0 NA NA NA NA NA NA NA 6761 FUN_013472 60 60 0 0 0 NA NA NA NA NA NA NA 6762 FUN_043719 0 14 15 1 13 NA NA NA NA NA NA NA 6763 FUN_010923 12583 1997 1444 892 32 NA NA NA NA NA NA NA 6764 FUN_043711 0 0 13 0 0 NA NA NA NA NA NA NA 6765 FUN_043710 0 0 0 0 10 NA NA NA NA NA NA NA 6766 FUN_043713 0 0 0 0 8 NA NA NA NA NA NA NA 6767 FUN_010929 2400 1542 905 1213 784 NA NA NA NA NA NA NA 6768 FUN_016182 190 122 14 68 66 NA NA NA NA NA NA NA 6769 FUN_016183 59 30 30 90 43 NA NA NA NA NA NA NA 6770 FUN_016180 1185 352 155 1675 906 NA NA NA NA NA NA NA 6771 FUN_016181 77 49 142 173 521 NA NA NA NA NA NA NA 6772 FUN_016186 16 0 2 47 48 NA NA NA NA NA NA NA 6773 FUN_016187 13 0 0 21 92 NA NA NA NA NA NA NA 6774 FUN_016184 230 174 225 369 217 NA NA NA NA NA NA NA 6775 FUN_016185 57 0 4 30 60 NA NA NA NA NA NA NA 6776 FUN_016188 30 4 23 152 116 NA NA NA NA NA NA NA 6777 FUN_016189 1146 71 702 207 330 NA NA NA NA NA NA NA 6778 FUN_023054 363 113 198 225 183 NA NA NA NA NA NA NA 6779 FUN_036808 319 1398 546 281 504 ptg000026l:2080789-2158658 Q9P215 2.03e-85 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 6780 FUN_023056 408 246 123 166 83 NA NA NA NA NA NA NA 6781 FUN_028085 19 31 11 64 6 NA NA NA NA NA NA NA 6782 FUN_028082 596 377 591 1582 1357 ptg000021l:15571438-15596336 B2RX12 7.01e-29 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multidrug resistance-associated protein 3) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; bile acid and bile salt transport [GO:0015721]; canalicular bile acid transport [GO:0015722]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006855; GO:0008559; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0015722; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0055085; GO:0071714; GO:0071716; GO:0098656 6783 FUN_028082 596 377 591 1582 1357 ptg000021l:15571438-15596336 B2RX12 1.28e-26 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multidrug resistance-associated protein 3) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; bile acid and bile salt transport [GO:0015721]; canalicular bile acid transport [GO:0015722]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006855; GO:0008559; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0015722; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0055085; GO:0071714; GO:0071716; GO:0098656 6784 FUN_028082 596 377 591 1582 1357 ptg000021l:15571438-15596336 B2RX12 1.28e-26 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multidrug resistance-associated protein 3) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; bile acid and bile salt transport [GO:0015721]; canalicular bile acid transport [GO:0015722]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006855; GO:0008559; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0015722; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0055085; GO:0071714; GO:0071716; GO:0098656 6785 FUN_028082 596 377 591 1582 1357 ptg000021l:15571438-15596336 B2RX12 6.39e-22 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multidrug resistance-associated protein 3) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; bile acid and bile salt transport [GO:0015721]; canalicular bile acid transport [GO:0015722]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006855; GO:0008559; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0015722; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0055085; GO:0071714; GO:0071716; GO:0098656 6786 FUN_023051 465 656 331 464 401 ptg000017l:3044554-3059587 A7Z052 2.76e-23 WD repeat-containing protein 6 Bos taurus (Bovine) cell cycle [GO:0007049]; tRNA methylation [GO:0030488] GO:0005737; GO:0007049; GO:0030488 6787 FUN_023052 0 48 74 66 125 NA NA NA NA NA NA NA 6788 FUN_023053 21 697 267 72 240 NA NA NA NA NA NA NA 6789 FUN_023059 202 704 274 279 351 NA NA NA NA NA NA NA 6790 FUN_028088 30910 20566 12661 31297 19874 ptg000021l:15674877-15692224 Q6RWA9 5e-44 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) (TNaK1-alpha) Taenia solium (Pork tapeworm) NA GO:0005391; GO:0005524; GO:0005886; GO:0016887; GO:0046872 6791 FUN_028088 30910 20566 12661 31297 19874 ptg000021l:15674877-15692224 Q6RWA9 2.54e-36 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) (TNaK1-alpha) Taenia solium (Pork tapeworm) NA GO:0005391; GO:0005524; GO:0005886; GO:0016887; GO:0046872 6792 FUN_028088 30910 20566 12661 31297 19874 ptg000021l:15674877-15692224 Q6RWA9 4.82e-34 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) (TNaK1-alpha) Taenia solium (Pork tapeworm) NA GO:0005391; GO:0005524; GO:0005886; GO:0016887; GO:0046872 6793 FUN_028088 30910 20566 12661 31297 19874 ptg000021l:15674877-15692224 Q6RWA9 1.23e-21 Sodium/potassium-transporting ATPase subunit alpha (Na(+)/K(+) ATPase alpha subunit) (EC 7.2.2.13) (Sodium pump subunit alpha) (TNaK1-alpha) Taenia solium (Pork tapeworm) NA GO:0005391; GO:0005524; GO:0005886; GO:0016887; GO:0046872 6794 FUN_028089 0 0 35 21 8 NA NA NA NA NA NA NA 6795 FUN_008879 1394 863 799 809 733 ptg000004l:225390-234473 Q3SWX9 6.39e-53 Double-strand-break repair protein rad21 homolog [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product)] Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromatin looping [GO:0140588]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of mitotic metaphase/anaphase transition [GO:0045841]; positive regulation of sister chromatid cohesion [GO:0045876]; protein localization to chromatin [GO:0071168]; regulation of transcription by RNA polymerase II [GO:0006357]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; sister chromatid cohesion [GO:0007062] GO:0000775; GO:0000785; GO:0000794; GO:0000922; GO:0003682; GO:0005654; GO:0005829; GO:0006357; GO:0006915; GO:0007062; GO:0008278; GO:0010972; GO:0016363; GO:0030496; GO:0045841; GO:0045876; GO:0051301; GO:0071168; GO:0140588; GO:1990414 6796 FUN_008879 1394 863 799 809 733 ptg000004l:225390-234473 Q3SWX9 6.39e-53 Double-strand-break repair protein rad21 homolog [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product)] Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; chromatin looping [GO:0140588]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of mitotic metaphase/anaphase transition [GO:0045841]; positive regulation of sister chromatid cohesion [GO:0045876]; protein localization to chromatin [GO:0071168]; regulation of transcription by RNA polymerase II [GO:0006357]; replication-born double-strand break repair via sister chromatid exchange [GO:1990414]; sister chromatid cohesion [GO:0007062] GO:0000775; GO:0000785; GO:0000794; GO:0000922; GO:0003682; GO:0005654; GO:0005829; GO:0006357; GO:0006915; GO:0007062; GO:0008278; GO:0010972; GO:0016363; GO:0030496; GO:0045841; GO:0045876; GO:0051301; GO:0071168; GO:0140588; GO:1990414 6797 FUN_008878 5950 4452 4343 5691 3575 NA NA NA NA NA NA NA 6798 FUN_008875 306 291 318 219 424 NA NA NA NA NA NA NA 6799 FUN_008874 91 102 187 118 109 ptg000004l:153907-157809 Q9BSF4 3.13e-27 Mitochondrial import inner membrane translocase subunit Tim29 (TIM29) Homo sapiens (Human) protein insertion into mitochondrial inner membrane [GO:0045039] GO:0005743; GO:0005758; GO:0042721; GO:0045039; GO:0140318 6800 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 3.26e-64 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6801 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 2.16e-48 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6802 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 8.67e-31 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6803 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 2.04e-30 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6804 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 3.43e-26 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6805 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 3.43e-26 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6806 FUN_008877 4319 2553 2582 4554 5189 ptg000004l:179479-220399 Q8IZQ1 3.43e-26 WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy) Homo sapiens (Human) aggrephagy [GO:0035973] GO:0000421; GO:0005545; GO:0005635; GO:0005654; GO:0005730; GO:0005737; GO:0005776; GO:0005829; GO:0005886; GO:0016020; GO:0016234; GO:0016605; GO:0030424; GO:0031965; GO:0035973; GO:0043204; GO:0046872 6807 FUN_008876 1393 1683 1158 1772 1720 ptg000004l:173643-178469 Q9QYC7 1.58e-43 Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) Mus musculus (Mouse) peptidyl-glutamic acid carboxylation [GO:0017187] GO:0005789; GO:0008488; GO:0017187; GO:0019842; GO:0043231 6808 FUN_008876 1393 1683 1158 1772 1720 ptg000004l:173643-178469 Q9QYC7 4.72e-36 Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) Mus musculus (Mouse) peptidyl-glutamic acid carboxylation [GO:0017187] GO:0005789; GO:0008488; GO:0017187; GO:0019842; GO:0043231 6809 FUN_008876 1393 1683 1158 1772 1720 ptg000004l:173643-178469 Q9QYC7 9.21e-29 Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) Mus musculus (Mouse) peptidyl-glutamic acid carboxylation [GO:0017187] GO:0005789; GO:0008488; GO:0017187; GO:0019842; GO:0043231 6810 FUN_008871 4871 2571 2438 3761 3187 NA NA NA NA NA NA NA 6811 FUN_008870 529 242 200 283 398 NA NA NA NA NA NA NA 6812 FUN_008873 3182 3981 1796 2632 1904 NA NA NA NA NA NA NA 6813 FUN_008872 3918 1666 2206 2584 3062 NA NA NA NA NA NA NA 6814 FUN_013298 52 338 335 113 59 NA NA NA NA NA NA NA 6815 FUN_028551 567 540 1395 2022 1137 ptg000022l:571060-571623 Q63ZK1 7.56e-44 Mitochondrial intermembrane space import and assembly protein 40-B (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4-B) Xenopus laevis (African clawed frog) 'de novo' post-translational protein folding [GO:0051084]; protein import into mitochondrial intermembrane space [GO:0045041]; protein maturation by protein folding [GO:0022417] GO:0005758; GO:0015035; GO:0022417; GO:0045041; GO:0051084 6816 FUN_013293 118 0 50 55 70 NA NA NA NA NA NA NA 6817 FUN_013295 27 20 0 39 5 NA NA NA NA NA NA NA 6818 FUN_028555 1 0 8 4 2 NA NA NA NA NA NA NA 6819 FUN_028556 314 338 160 294 163 NA NA NA NA NA NA NA 6820 FUN_028557 150 758 43 217 440 NA NA NA NA NA NA NA 6821 FUN_029657 31 92 169 116 195 ptg000023l:4183656-4189727 E7FAM5 9.12e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 6822 FUN_041623 490 116 139 549 161 NA NA NA NA NA NA NA 6823 FUN_041622 1683 54 2078 1583 1837 ptg000035l:5981570-5984716 P41247 1.94e-32 Patatin-like phospholipase domain-containing protein 4 (EC 3.1.1.3) (Calcium-independent phospholipase A2-eta) (iPLA2-eta) (EC 3.1.1.4) (Protein GS2) Homo sapiens (Human) lipid homeostasis [GO:0055088]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005737; GO:0005739; GO:0005811; GO:0005829; GO:0016020; GO:0016411; GO:0019433; GO:0047376; GO:0050253; GO:0051264; GO:0051265; GO:0055088 6824 FUN_041621 2413 2369 2339 3089 1590 NA NA NA NA NA NA NA 6825 FUN_041620 119 17 74 109 128 ptg000035l:5969923-5972209 P70579 3.69e-31 Metabotropic glutamate receptor 8 (mGluR8) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron death [GO:1901214]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001642; GO:0004930; GO:0005886; GO:0007193; GO:0007196; GO:0007216; GO:0007268; GO:0008066; GO:0019233; GO:0035249; GO:0042734; GO:0043005; GO:0043025; GO:0045211; GO:0046928; GO:0048787; GO:0050966; GO:0051966; GO:0098978; GO:0098982; GO:0099171; GO:1901214 6826 FUN_041627 50 0 63 9 263 NA NA NA NA NA NA NA 6827 FUN_041626 107 0 60 19 442 NA NA NA NA NA NA NA 6828 FUN_041625 39 0 56 9 471 NA NA NA NA NA NA NA 6829 FUN_041624 39 0 0 37 377 NA NA NA NA NA NA NA 6830 FUN_041629 30500 14015 13631 25353 24135 NA NA NA NA NA NA NA 6831 FUN_041628 1704 3580 952 1998 1358 NA NA NA NA NA NA NA 6832 FUN_014128 71 0 3 5 126 NA NA NA NA NA NA NA 6833 FUN_014129 4 0 26 0 33 NA NA NA NA NA NA NA 6834 FUN_014127 69 0 0 66 0 NA NA NA NA NA NA NA 6835 FUN_014124 299 15 15 45 7 NA NA NA NA NA NA NA 6836 FUN_014125 2 0 8 2 1 NA NA NA NA NA NA NA 6837 FUN_014122 88 87 92 89 57 NA NA NA NA NA NA NA 6838 FUN_014123 1646 1041 1139 1001 3243 ptg000008l:31971615-32032292 Q9NBX4 2.24e-21 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 6839 FUN_007074 336 408 78 212 230 NA NA NA NA NA NA NA 6840 FUN_025049 31 3 0 0 0 NA NA NA NA NA NA NA 6841 FUN_025048 184 91 3 0 0 NA NA NA NA NA NA NA 6842 FUN_043237 882 388 323 900 941 ptg000047l:5786946-5802004 Q8BKF1 1.01e-29 DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6) Mus musculus (Mouse) mitochondrial transcription [GO:0006390]; transcription initiation at mitochondrial promoter [GO:0006391] GO:0000175; GO:0001018; GO:0003896; GO:0003899; GO:0005739; GO:0005759; GO:0006390; GO:0006391; GO:0032991; GO:0034245; GO:0042645; GO:0043565 6843 FUN_043237 882 388 323 900 941 ptg000047l:5786946-5802004 Q8BKF1 4.28e-23 DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6) Mus musculus (Mouse) mitochondrial transcription [GO:0006390]; transcription initiation at mitochondrial promoter [GO:0006391] GO:0000175; GO:0001018; GO:0003896; GO:0003899; GO:0005739; GO:0005759; GO:0006390; GO:0006391; GO:0032991; GO:0034245; GO:0042645; GO:0043565 6844 FUN_025045 0 0 0 0 18 NA NA NA NA NA NA NA 6845 FUN_022016 10167 6669 5644 9058 5491 NA NA NA NA NA NA NA 6846 FUN_025046 387 156 61 0 0 NA NA NA NA NA NA NA 6847 FUN_022012 277 97 632 276 191 NA NA NA NA NA NA NA 6848 FUN_022010 0 0 9 0 0 NA NA NA NA NA NA NA 6849 FUN_024312 15 0 0 0 0 NA NA NA NA NA NA NA 6850 FUN_024310 25 14 0 0 24 ptg000018l:4763977-4767580 B0FPE9 9.98e-44 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Macaca mulatta (Rhesus macaque) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 6851 FUN_024311 0 5 20 0 27 NA NA NA NA NA NA NA 6852 FUN_024316 18 109 12 73 14 ptg000018l:4837086-4842084 Q8K3Z0 7.51e-36 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 6853 FUN_024317 0 0 54 9 0 NA NA NA NA NA NA NA 6854 FUN_024314 1 0 10 1 0 NA NA NA NA NA NA NA 6855 FUN_024315 10 0 4 5 4 ptg000018l:4807840-4815002 Q8K3Z0 3.27e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 6856 FUN_007070 40 20 7 27 31 NA NA NA NA NA NA NA 6857 FUN_024318 8 0 40 55 9 NA NA NA NA NA NA NA 6858 FUN_024319 51 69 24 164 30 ptg000018l:4867697-4871165 Q7RTR2 1.28e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6859 FUN_007071 23 105 44 122 54 NA NA NA NA NA NA NA 6860 FUN_007072 15 168 112 250 25 NA NA NA NA NA NA NA 6861 FUN_043231 4405 6185 2930 3864 1175 NA NA NA NA NA NA NA 6862 FUN_015298 7336 5601 3374 5537 2383 NA NA NA NA NA NA NA 6863 FUN_015297 102 105 143 101 152 ptg000009l:8569266-8572668 F1NZI4 1.06e-89 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 6864 FUN_015297 102 105 143 101 152 ptg000009l:8569266-8572668 F1NZI4 5.21e-37 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 6865 FUN_015297 102 105 143 101 152 ptg000009l:8569266-8572668 F1NZI4 5.21e-37 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 6866 FUN_015296 44 92 32 205 104 NA NA NA NA NA NA NA 6867 FUN_015295 24933 16373 14243 22011 16376 NA NA NA NA NA NA NA 6868 FUN_015294 1341 833 378 1546 957 NA NA NA NA NA NA NA 6869 FUN_015293 2926 1765 1595 2503 2504 NA NA NA NA NA NA NA 6870 FUN_015292 5567 4890 3386 3263 2941 ptg000009l:8493806-8497571 P22439 1.78e-31 Pyruvate dehydrogenase protein X component (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (proX) Bos taurus (Bovine) NA GO:0005739; GO:0005967; GO:0016746; GO:0034604; GO:0045254 6871 FUN_015292 5567 4890 3386 3263 2941 ptg000009l:8493806-8497571 P22439 7.87e-31 Pyruvate dehydrogenase protein X component (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (proX) Bos taurus (Bovine) NA GO:0005739; GO:0005967; GO:0016746; GO:0034604; GO:0045254 6872 FUN_015292 5567 4890 3386 3263 2941 ptg000009l:8493806-8497571 P22439 2.2e-30 Pyruvate dehydrogenase protein X component (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (proX) Bos taurus (Bovine) NA GO:0005739; GO:0005967; GO:0016746; GO:0034604; GO:0045254 6873 FUN_015291 1571 1866 864 1431 1237 NA NA NA NA NA NA NA 6874 FUN_015290 566 155 119 439 288 ptg000009l:8478585-8483900 O15439 2.67e-77 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 6875 FUN_015290 566 155 119 439 288 ptg000009l:8478585-8483900 O15439 1.8e-52 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 6876 FUN_015290 566 155 119 439 288 ptg000009l:8478585-8483900 O15439 4.18e-30 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 6877 FUN_022200 8875 11203 7842 7674 5487 NA NA NA NA NA NA NA 6878 FUN_041407 198 238 107 192 168 NA NA NA NA NA NA NA 6879 FUN_038432 2498 2015 924 1446 977 ptg000027l:7232528-7233182 P61214 5.65e-51 ADP-ribosylation factor-like protein 4A Rattus norvegicus (Rat) brown fat cell differentiation [GO:0050873]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005634; GO:0005730; GO:0005737; GO:0005886; GO:0006886; GO:0016192; GO:0050873 6880 FUN_014737 1528 869 1131 1500 1546 NA NA NA NA NA NA NA 6881 FUN_038430 2469 1547 1482 2609 2553 ptg000027l:7179345-7215499 Q6P4S8 5.49e-23 Integrator complex subunit 1 (Int1) Mus musculus (Mouse) blastocyst growth [GO:0001832]; inner cell mass cell proliferation [GO:0001833]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; snRNA processing [GO:0016180]; U2 snRNA 3'-end processing [GO:0034474] GO:0001832; GO:0001833; GO:0005634; GO:0016180; GO:0031965; GO:0032039; GO:0034474; GO:0043066; GO:0043154 6882 FUN_038431 1716 4257 629 1084 1161 ptg000027l:7217168-7231156 F4IE66 9e-22 Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH10 (EC 3.6.4.13) (DEAH RNA helicase homolog PRP22) (Protein ROOT INITIATION DEFECTIVE 1) Arabidopsis thaliana (Mouse-ear cress) mRNA processing [GO:0006397]; positive regulation of transcription by RNA polymerase I [GO:0045943]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0006397; GO:0008380; GO:0016887; GO:0043484; GO:0045943 6883 FUN_038436 1003 612 407 637 1159 NA NA NA NA NA NA NA 6884 FUN_038437 4639 5339 2631 8574 5064 NA NA NA NA NA NA NA 6885 FUN_038434 1043 654 734 829 550 NA NA NA NA NA NA NA 6886 FUN_038435 4737 3745 2156 3469 1927 NA NA NA NA NA NA NA 6887 FUN_038438 1101 658 710 1209 1090 ptg000027l:7300703-7306577 Q7ZXV8 1.76e-37 BUB3-interacting and GLEBS motif-containing protein ZNF207 (BuGZ) (xBuGZ) (Zinc finger protein 207) Xenopus laevis (African clawed frog) attachment of spindle microtubules to kinetochore [GO:0008608]; cell division [GO:0051301]; microtubule bundle formation [GO:0001578]; microtubule polymerization [GO:0046785]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; protein stabilization [GO:0050821]; regulation of chromosome segregation [GO:0051983] GO:0000070; GO:0000776; GO:0001578; GO:0005634; GO:0005737; GO:0005819; GO:0005874; GO:0007094; GO:0008017; GO:0008608; GO:0046785; GO:0046872; GO:0050821; GO:0051301; GO:0051983; GO:0090307; GO:1990047 6888 FUN_038439 1210 993 790 904 990 NA NA NA NA NA NA NA 6889 FUN_013103 0 0 6 0 0 NA NA NA NA NA NA NA 6890 FUN_031714 1306 1058 891 2054 1188 NA NA NA NA NA NA NA 6891 FUN_023830 0 0 2 0 11 NA NA NA NA NA NA NA 6892 FUN_023831 3 0 8 0 0 NA NA NA NA NA NA NA 6893 FUN_031718 253 186 121 406 336 NA NA NA NA NA NA NA 6894 FUN_031719 337 200 253 520 603 NA NA NA NA NA NA NA 6895 FUN_039522 38 0 32 0 157 ptg000030l:1007347-1010441 Q6LAF1 4.13e-41 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6896 FUN_039521 0 0 0 0 17 ptg000030l:1005288-1005827 P35067 1.73e-56 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6897 FUN_013106 24 17 19 4 20 NA NA NA NA NA NA NA 6898 FUN_015927 19 29 13 10 40 NA NA NA NA NA NA NA 6899 FUN_033682 5 0 0 38 4 NA NA NA NA NA NA NA 6900 FUN_033683 642 369 602 733 867 NA NA NA NA NA NA NA 6901 FUN_028171 852 270 422 622 523 NA NA NA NA NA NA NA 6902 FUN_026927 326 17 0 364 112 ptg000020l:15027026-15030542 O55171 1.44e-35 Acyl-coenzyme A thioesterase 2, mitochondrial (Acyl-CoA thioesterase 2) (EC 3.1.2.2) (ARTISt/p43) (Acyl coenzyme A thioester hydrolase) (MTE-I) (Very-long-chain acyl-CoA thioesterase) Rattus norvegicus (Rat) acyl-CoA metabolic process [GO:0006637]; fatty acid metabolic process [GO:0006631]; long-chain fatty acid metabolic process [GO:0001676]; response to epidermal growth factor [GO:0070849]; response to hormone [GO:0009725]; response to hypoxia [GO:0001666]; response to nutrient levels [GO:0031667]; response to xenobiotic stimulus [GO:0009410]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0001666; GO:0001676; GO:0005739; GO:0005759; GO:0006631; GO:0006637; GO:0009410; GO:0009725; GO:0016290; GO:0031667; GO:0042760; GO:0047617; GO:0070849; GO:0102991 6903 FUN_026922 0 2 0 0 95 NA NA NA NA NA NA NA 6904 FUN_026929 0 0 0 0 13 NA NA NA NA NA NA NA 6905 FUN_026928 230 0 37 13 364 NA NA NA NA NA NA NA 6906 FUN_039383 54 292 22 55 38 NA NA NA NA NA NA NA 6907 FUN_037738 724 351 275 905 662 ptg000026l:12986299-12990521 Q76KP1 9.84e-23 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 6908 FUN_039381 149 31 27 319 78 ptg000029c:997005-1006442 B9IUR6 1.31e-39 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain Q1) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 6909 FUN_039380 31 84 11 32 60 ptg000029c:903931-994707 P20825 1.75e-90 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 6910 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 8.63e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6911 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 9.23e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6912 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 3.64e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6913 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 9.58e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6914 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 4.82e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6915 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 1.03e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6916 FUN_039387 68 0 58 53 127 ptg000029c:1097765-1104505 Q7RTR2 4.71e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6917 FUN_039386 6 0 0 51 0 NA NA NA NA NA NA NA 6918 FUN_039384 921 421 435 425 462 ptg000029c:1035193-1040388 Q7RTR2 4.51e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6919 FUN_039384 921 421 435 425 462 ptg000029c:1035193-1040388 Q7RTR2 1.85e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6920 FUN_039384 921 421 435 425 462 ptg000029c:1035193-1040388 Q7RTR2 1.45e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6921 FUN_039384 921 421 435 425 462 ptg000029c:1035193-1040388 Q7RTR2 7.35e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 6922 FUN_027030 7 16 4 16 5 NA NA NA NA NA NA NA 6923 FUN_027037 0 0 0 0 8 NA NA NA NA NA NA NA 6924 FUN_027035 0 0 0 0 35 NA NA NA NA NA NA NA 6925 FUN_027038 0 0 0 0 19 NA NA NA NA NA NA NA 6926 FUN_037737 0 0 7 0 74 NA NA NA NA NA NA NA 6927 FUN_000066 3 0 3 0 7 ntLink_4:45175-47490 P35061 6.65e-78 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6928 FUN_000067 8 1 13 1 24 ntLink_4:47756-48519 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6929 FUN_005012 72 2 54 34 28 NA NA NA NA NA NA NA 6930 FUN_026075 56 42 39 45 57 NA NA NA NA NA NA NA 6931 FUN_019477 0 0 0 0 18 NA NA NA NA NA NA NA 6932 FUN_026077 563 176 104 308 279 NA NA NA NA NA NA NA 6933 FUN_000065 3 0 5 0 12 ntLink_4:39254-40035 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6934 FUN_026071 264 52 77 131 96 NA NA NA NA NA NA NA 6935 FUN_026070 629 637 425 604 601 NA NA NA NA NA NA NA 6936 FUN_026073 1939 1705 793 1294 1013 NA NA NA NA NA NA NA 6937 FUN_030011 55 0 4 130 40 NA NA NA NA NA NA NA 6938 FUN_026079 1752 1398 919 1482 1127 ptg000020l:4385668-4397688 Q562C6 1.45e-23 Leucine zipper transcription factor-like protein 1 Rattus norvegicus (Rat) flagellated sperm motility [GO:0030317]; negative regulation of protein localization to ciliary membrane [GO:1903568]; negative regulation of protein localization to cilium [GO:1903565]; spermatogenesis [GO:0007283] GO:0002177; GO:0005737; GO:0005829; GO:0005929; GO:0007283; GO:0030317; GO:0042802; GO:0044877; GO:0062063; GO:1903565; GO:1903568 6939 FUN_030012 0 0 32 20 0 NA NA NA NA NA NA NA 6940 FUN_000063 8 0 15 1 21 ntLink_4:35558-36321 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6941 FUN_035127 10 2 0 1 3 NA NA NA NA NA NA NA 6942 FUN_005016 0 0 0 0 19 NA NA NA NA NA NA NA 6943 FUN_019473 18 4 0 5 8 NA NA NA NA NA NA NA 6944 FUN_005017 29 148 63 79 88 NA NA NA NA NA NA NA 6945 FUN_035124 2077 174 25 73 87 ptg000025l:4221477-4225366 Q8BHB0 1.26e-40 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 6946 FUN_019471 0 0 15 24 81 NA NA NA NA NA NA NA 6947 FUN_035123 4 14 5 0 4 NA NA NA NA NA NA NA 6948 FUN_019470 3 0 10 0 35 NA NA NA NA NA NA NA 6949 FUN_030337 5 0 4 0 22 ptg000023l:10636889-10637652 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 6950 FUN_035120 6 11 1 0 12 NA NA NA NA NA NA NA 6951 FUN_022214 81 35 214 190 389 ptg000016l:6399631-6404129 Q0D2E8 4.05e-100 Protein RFT1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) carbohydrate transport [GO:0008643]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488] GO:0006488; GO:0008643; GO:0016020 6952 FUN_022214 81 35 214 190 389 ptg000016l:6399631-6404129 Q0D2E8 3.94e-21 Protein RFT1 homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) carbohydrate transport [GO:0008643]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488] GO:0006488; GO:0008643; GO:0016020 6953 FUN_004378 382 212 201 277 295 NA NA NA NA NA NA NA 6954 FUN_004379 776 571 350 1238 910 NA NA NA NA NA NA NA 6955 FUN_004376 3290 3950 2426 1434 908 ntLink_8:22529421-22530519 B0UYI1 1.7e-28 Transcription elongation factor A N-terminal and central domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) DNA-templated transcription [GO:0006351] GO:0005634; GO:0006351 6956 FUN_004376 3290 3950 2426 1434 908 ntLink_8:22529421-22530519 B0UYI1 1.7e-28 Transcription elongation factor A N-terminal and central domain-containing protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) DNA-templated transcription [GO:0006351] GO:0005634; GO:0006351 6957 FUN_004377 866 373 505 823 689 NA NA NA NA NA NA NA 6958 FUN_004375 1189 1438 678 1133 1039 ntLink_8:22526911-22528453 Q7KWX9 7.29e-21 Putative exosome complex component rrp40 (Exosome component 3) (Ribosomal RNA-processing protein 40) Dictyostelium discoideum (Social amoeba) CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005730; GO:0034427; GO:0034475; GO:0043928; GO:0071034; GO:0071035; GO:0071038; GO:0071051 6959 FUN_004375 1189 1438 678 1133 1039 ntLink_8:22526911-22528453 Q7KWX9 7.29e-21 Putative exosome complex component rrp40 (Exosome component 3) (Ribosomal RNA-processing protein 40) Dictyostelium discoideum (Social amoeba) CUT catabolic process [GO:0071034]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005730; GO:0034427; GO:0034475; GO:0043928; GO:0071034; GO:0071035; GO:0071038; GO:0071051 6960 FUN_004373 12365 7530 7090 15070 11047 ntLink_8:22489716-22520692 Q64604 5.91e-23 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Rattus norvegicus (Rat) cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560] GO:0001960; GO:0004725; GO:0005001; GO:0005158; GO:0005768; GO:0005886; GO:0006470; GO:0007156; GO:0007399; GO:0008201; GO:0008285; GO:0010975; GO:0016020; GO:0016477; GO:0030426; GO:0030971; GO:0031102; GO:0031345; GO:0035335; GO:0035373; GO:0042059; GO:0042301; GO:0043005; GO:0043025; GO:0043065; GO:0043231; GO:0043525; GO:0044877; GO:0046627; GO:0048679; GO:0050775; GO:0050803; GO:0050839; GO:0051387; GO:0060076; GO:0098839; GO:0099175; GO:0099560; GO:1900121 6961 FUN_004373 12365 7530 7090 15070 11047 ntLink_8:22489716-22520692 Q64604 5.91e-23 Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR) Rattus norvegicus (Rat) cell migration [GO:0016477]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell projection organization [GO:0031345]; negative regulation of cytokine-mediated signaling pathway [GO:0001960]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of neurotrophin TRK receptor signaling pathway [GO:0051387]; negative regulation of receptor binding [GO:1900121]; nervous system development [GO:0007399]; neuron projection regeneration [GO:0031102]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of neuron apoptotic process [GO:0043525]; protein dephosphorylation [GO:0006470]; regulation of axon regeneration [GO:0048679]; regulation of neuron projection development [GO:0010975]; regulation of postsynapse organization [GO:0099175]; regulation of synapse structure or activity [GO:0050803]; synaptic membrane adhesion [GO:0099560] GO:0001960; GO:0004725; GO:0005001; GO:0005158; GO:0005768; GO:0005886; GO:0006470; GO:0007156; GO:0007399; GO:0008201; GO:0008285; GO:0010975; GO:0016020; GO:0016477; GO:0030426; GO:0030971; GO:0031102; GO:0031345; GO:0035335; GO:0035373; GO:0042059; GO:0042301; GO:0043005; GO:0043025; GO:0043065; GO:0043231; GO:0043525; GO:0044877; GO:0046627; GO:0048679; GO:0050775; GO:0050803; GO:0050839; GO:0051387; GO:0060076; GO:0098839; GO:0099175; GO:0099560; GO:1900121 6962 FUN_004370 26 12 0 18 7 NA NA NA NA NA NA NA 6963 FUN_004371 191 377 118 260 136 NA NA NA NA NA NA NA 6964 FUN_018106 12 30 17 144 58 NA NA NA NA NA NA NA 6965 FUN_018107 12 26 13 67 34 NA NA NA NA NA NA NA 6966 FUN_018100 0 0 10 0 0 NA NA NA NA NA NA NA 6967 FUN_025528 2143 955 868 1629 1156 NA NA NA NA NA NA NA 6968 FUN_025529 1144 572 505 1137 990 NA NA NA NA NA NA NA 6969 FUN_025522 0 42 7 0 1 NA NA NA NA NA NA NA 6970 FUN_025520 3661 4600 2550 2433 1447 NA NA NA NA NA NA NA 6971 FUN_025521 0 19 5 0 38 NA NA NA NA NA NA NA 6972 FUN_025526 0 0 22 0 15 NA NA NA NA NA NA NA 6973 FUN_025527 3238 2199 1795 2194 1931 ptg000019l:3875137-3895365 O60941 4.65e-21 Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) Homo sapiens (Human) neuron differentiation [GO:0030182]; synaptic signaling [GO:0099536] GO:0005634; GO:0005737; GO:0005886; GO:0008270; GO:0009925; GO:0014069; GO:0030182; GO:0030425; GO:0045202; GO:0060077; GO:0099536 6974 FUN_005965 69 93 57 0 224 NA NA NA NA NA NA NA 6975 FUN_005966 13 0 0 0 21 NA NA NA NA NA NA NA 6976 FUN_005967 392 736 401 0 195 NA NA NA NA NA NA NA 6977 FUN_005960 83 0 55 114 15 NA NA NA NA NA NA NA 6978 FUN_005961 382 70 329 405 490 NA NA NA NA NA NA NA 6979 FUN_005962 355 224 296 326 132 NA NA NA NA NA NA NA 6980 FUN_005963 300 244 128 137 39 NA NA NA NA NA NA NA 6981 FUN_019767 7 75 9 25 41 NA NA NA NA NA NA NA 6982 FUN_019766 16 17 19 0 124 NA NA NA NA NA NA NA 6983 FUN_019765 0 10 21 3 21 NA NA NA NA NA NA NA 6984 FUN_019760 36 24 46 89 23 NA NA NA NA NA NA NA 6985 FUN_034979 235 681 338 54 431 NA NA NA NA NA NA NA 6986 FUN_034978 37 0 0 0 57 NA NA NA NA NA NA NA 6987 FUN_034977 329 38 24 111 1173 NA NA NA NA NA NA NA 6988 FUN_034976 0 0 0 0 179 NA NA NA NA NA NA NA 6989 FUN_034975 8 0 0 0 66 NA NA NA NA NA NA NA 6990 FUN_034974 374 271 155 133 235 NA NA NA NA NA NA NA 6991 FUN_034973 2191 2230 1323 1397 1512 NA NA NA NA NA NA NA 6992 FUN_034972 1355 563 281 516 952 ptg000025l:2236074-2240737 Q91820 6.12e-28 Aurora kinase A-A (EC 2.7.11.1) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 6-A) (Serine/threonine-protein kinase Eg2-A) (pEg2) (Serine/threonine-protein kinase aurora-A) (p46Eg265) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic spindle organization [GO:0000212]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] GO:0000212; GO:0000922; GO:0004674; GO:0005524; GO:0005737; GO:0005813; GO:0005876; GO:0007100; GO:0008017; GO:0018105; GO:0019894; GO:0046777; GO:0051301; GO:0090307; GO:0106310 6993 FUN_034972 1355 563 281 516 952 ptg000025l:2236074-2240737 Q91820 6.12e-28 Aurora kinase A-A (EC 2.7.11.1) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Serine/threonine-protein kinase 6-A) (Serine/threonine-protein kinase Eg2-A) (pEg2) (Serine/threonine-protein kinase aurora-A) (p46Eg265) Xenopus laevis (African clawed frog) cell division [GO:0051301]; meiotic spindle organization [GO:0000212]; mitotic centrosome separation [GO:0007100]; mitotic spindle assembly [GO:0090307]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] GO:0000212; GO:0000922; GO:0004674; GO:0005524; GO:0005737; GO:0005813; GO:0005876; GO:0007100; GO:0008017; GO:0018105; GO:0019894; GO:0046777; GO:0051301; GO:0090307; GO:0106310 6994 FUN_034971 321 55 42 111 144 NA NA NA NA NA NA NA 6995 FUN_034970 929 317 258 529 468 ptg000025l:2225942-2231567 P34059 6.01e-26 N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) Homo sapiens (Human) NA GO:0003943; GO:0004065; GO:0005576; GO:0008484; GO:0035578; GO:0043202; GO:0043890; GO:0046872; GO:0070062 6996 FUN_034970 929 317 258 529 468 ptg000025l:2225942-2231567 P34059 6.01e-26 N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) Homo sapiens (Human) NA GO:0003943; GO:0004065; GO:0005576; GO:0008484; GO:0035578; GO:0043202; GO:0043890; GO:0046872; GO:0070062 6997 FUN_035598 1184 1115 1196 2916 1150 ptg000025l:9684877-9706781 A1Z9L3 1.72e-31 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (Peanuts) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; mRNA splicing, via spliceosome [GO:0000398]; oogenesis [GO:0048477]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex disassembly [GO:0000390]; ventral cord development [GO:0007419] GO:0000381; GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0006325; GO:0007419; GO:0016887; GO:0030261; GO:0048477; GO:0071011; GO:0071013 6998 FUN_035598 1184 1115 1196 2916 1150 ptg000025l:9684877-9706781 A1Z9L3 1.72e-31 ATP-dependent RNA helicase DHX8 (EC 3.6.4.13) (Peanuts) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; mRNA splicing, via spliceosome [GO:0000398]; oogenesis [GO:0048477]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; spliceosomal complex disassembly [GO:0000390]; ventral cord development [GO:0007419] GO:0000381; GO:0000390; GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0006325; GO:0007419; GO:0016887; GO:0030261; GO:0048477; GO:0071011; GO:0071013 6999 FUN_035599 393 115 123 80 124 ptg000025l:9710866-9713213 Q9FWW9 6.16e-32 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 7000 FUN_035592 9 214 8 0 0 NA NA NA NA NA NA NA 7001 FUN_035593 0 210 0 0 0 NA NA NA NA NA NA NA 7002 FUN_035590 0 49 0 21 78 NA NA NA NA NA NA NA 7003 FUN_035591 22 13 6 11 33 NA NA NA NA NA NA NA 7004 FUN_035596 4 37 0 19 0 NA NA NA NA NA NA NA 7005 FUN_035597 404 209 120 503 66 NA NA NA NA NA NA NA 7006 FUN_035594 155 149 97 342 238 NA NA NA NA NA NA NA 7007 FUN_006266 2071 1758 1147 2303 2075 NA NA NA NA NA NA NA 7008 FUN_042021 5232 5466 2741 4174 3043 NA NA NA NA NA NA NA 7009 FUN_042022 556 628 702 904 1039 NA NA NA NA NA NA NA 7010 FUN_042023 3959 3093 2313 3813 3082 ptg000035l:9859193-9867650 Q0V9R4 8.47e-34 Coiled-coil domain-containing protein 39 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inner dynein arm assembly [GO:0036159] GO:0005576; GO:0005930; GO:0036159; GO:0060285; GO:0060287; GO:0070286 7011 FUN_006262 7890 3706 3747 1288 1860 NA NA NA NA NA NA NA 7012 FUN_006263 2134 660 852 228 290 NA NA NA NA NA NA NA 7013 FUN_006260 11 27 4 355 139 ptg000001l:9806220-9807399 Q9Y5X5 6.3e-42 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 7014 FUN_042027 1171 1147 872 957 811 NA NA NA NA NA NA NA 7015 FUN_042028 2123 1381 1296 1244 978 NA NA NA NA NA NA NA 7016 FUN_042029 1266 734 532 997 1085 NA NA NA NA NA NA NA 7017 FUN_006268 51 169 47 81 85 ptg000001l:9937845-9940315 Q96KE9 9.88e-56 BTB/POZ domain-containing protein 6 (Lens BTB domain protein) Homo sapiens (Human) neurogenesis [GO:0022008] GO:0005829; GO:0022008 7018 FUN_006269 1499 617 858 820 745 NA NA NA NA NA NA NA 7019 FUN_037998 168 316 173 267 271 ptg000027l:1274382-1277509 Q5HZT0 4.02e-30 Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-) Xenopus laevis (African clawed frog) mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; nuclear mRNA surveillance [GO:0071028]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] GO:0000166; GO:0000287; GO:0003729; GO:0005634; GO:0006402; GO:0008409; GO:0034353; GO:0050779; GO:0071028; GO:0090305; GO:0110152; GO:0110155 7020 FUN_037998 168 316 173 267 271 ptg000027l:1274382-1277509 Q5HZT0 8.65e-24 Decapping and exoribonuclease protein (DXO) (EC 3.6.1.-) (5'-3' exoribonuclease DXO) (EC 3.1.13.-) (Dom-3 homolog Z) (NAD-capped RNA hydrolase DXO) (DeNADding enzyme DXO) (EC 3.6.1.-) Xenopus laevis (African clawed frog) mRNA catabolic process [GO:0006402]; NAD-cap decapping [GO:0110155]; nuclear mRNA surveillance [GO:0071028]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; RNA destabilization [GO:0050779] GO:0000166; GO:0000287; GO:0003729; GO:0005634; GO:0006402; GO:0008409; GO:0034353; GO:0050779; GO:0071028; GO:0090305; GO:0110152; GO:0110155 7021 FUN_037999 923 847 549 1317 1384 NA NA NA NA NA NA NA 7022 FUN_037994 0 0 0 0 8 NA NA NA NA NA NA NA 7023 FUN_037996 1068 2038 1206 1685 1113 NA NA NA NA NA NA NA 7024 FUN_037997 73 41 52 58 167 ptg000027l:1272309-1273659 Q5BB35 9.96e-65 Pre-mRNA-splicing factor cwc2 Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) cell cycle [GO:0007049]; mRNA cis splicing, via spliceosome [GO:0045292]; positive regulation of cell cycle [GO:0045787]; positive regulation of RNA splicing [GO:0033120]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000974; GO:0007049; GO:0017070; GO:0033120; GO:0036002; GO:0045292; GO:0045787; GO:0046872; GO:0071006; GO:0071007; GO:0071014 7025 FUN_037990 1961 1222 643 2359 1263 ptg000027l:1208888-1214411 Q9NXV2 3.98e-31 BTB/POZ domain-containing protein KCTD5 Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein homooligomerization [GO:0051260] GO:0005634; GO:0005737; GO:0005829; GO:0031463; GO:0042802; GO:0043161; GO:0044877; GO:0051260; GO:0097602 7026 FUN_037992 1979 2948 1872 2222 1286 NA NA NA NA NA NA NA 7027 FUN_037993 1212 719 1094 1350 1146 NA NA NA NA NA NA NA 7028 FUN_035628 2953 1772 884 2216 1426 NA NA NA NA NA NA NA 7029 FUN_035629 1008 689 829 1128 708 NA NA NA NA NA NA NA 7030 FUN_035624 523 331 125 321 411 NA NA NA NA NA NA NA 7031 FUN_035625 791 528 420 1093 754 NA NA NA NA NA NA NA 7032 FUN_035626 5206 6948 4303 4883 3171 NA NA NA NA NA NA NA 7033 FUN_035627 77 63 24 29 93 NA NA NA NA NA NA NA 7034 FUN_035620 59 51 35 28 2 NA NA NA NA NA NA NA 7035 FUN_035621 62 74 33 29 47 NA NA NA NA NA NA NA 7036 FUN_035622 77 135 14 102 28 NA NA NA NA NA NA NA 7037 FUN_035623 0 4 10 0 26 NA NA NA NA NA NA NA 7038 FUN_032018 5458 8336 4170 4145 3718 NA NA NA NA NA NA NA 7039 FUN_032019 4438 3064 1858 2765 1792 NA NA NA NA NA NA NA 7040 FUN_032016 1781 993 1007 2457 2327 ptg000023l:27954553-27992866 Q8R3Y8 3.74e-47 Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000209; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0046872; GO:0061630 7041 FUN_032016 1781 993 1007 2457 2327 ptg000023l:27954553-27992866 Q8R3Y8 6.16e-29 Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; protein polyubiquitination [GO:0000209]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000209; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0046872; GO:0061630 7042 FUN_032017 4673 1246 1530 3984 1881 ptg000023l:27993217-27996247 F7AEX0 7e-67 UV-stimulated scaffold protein A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000993; GO:0005694; GO:0006283; GO:0009411; GO:0016567 7043 FUN_032017 4673 1246 1530 3984 1881 ptg000023l:27993217-27996247 F7AEX0 5.26e-34 UV-stimulated scaffold protein A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein ubiquitination [GO:0016567]; response to UV [GO:0009411]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000993; GO:0005694; GO:0006283; GO:0009411; GO:0016567 7044 FUN_032014 467 525 291 681 368 NA NA NA NA NA NA NA 7045 FUN_032015 438 710 400 954 562 NA NA NA NA NA NA NA 7046 FUN_032012 4690 1370 755 2887 2016 NA NA NA NA NA NA NA 7047 FUN_032013 974 645 519 1175 374 NA NA NA NA NA NA NA 7048 FUN_032010 1220 1473 1011 1299 1187 ptg000023l:27877960-27879511 P12394 5.22e-102 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] GO:0004508; GO:0005506; GO:0006694; GO:0008202; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 7049 FUN_032011 0 8 5 12 12 NA NA NA NA NA NA NA 7050 FUN_030661 8 59 34 23 96 NA NA NA NA NA NA NA 7051 FUN_043868 17 2 32 4 71 NA NA NA NA NA NA NA 7052 FUN_043867 0 0 0 3 16 NA NA NA NA NA NA NA 7053 FUN_043866 0 0 7 0 6 NA NA NA NA NA NA NA 7054 FUN_007610 0 0 0 209 26 NA NA NA NA NA NA NA 7055 FUN_007611 0 5 0 110 9 NA NA NA NA NA NA NA 7056 FUN_007612 0 0 0 12 0 NA NA NA NA NA NA NA 7057 FUN_008501 98 46 9 124 46 NA NA NA NA NA NA NA 7058 FUN_008500 10 8 0 2 0 NA NA NA NA NA NA NA 7059 FUN_008503 1 2 4 11 19 NA NA NA NA NA NA NA 7060 FUN_008502 3 2 46 23 220 NA NA NA NA NA NA NA 7061 FUN_008504 3 0 5 8 18 NA NA NA NA NA NA NA 7062 FUN_008507 4 2 7 9 24 NA NA NA NA NA NA NA 7063 FUN_008506 6 21 91 39 428 NA NA NA NA NA NA NA 7064 FUN_008509 2 2 8 8 18 NA NA NA NA NA NA NA 7065 FUN_008508 9 18 102 71 490 NA NA NA NA NA NA NA 7066 FUN_041700 2886 2197 1250 2126 1566 ptg000035l:6661337-6666912 Q9QZC4 3.23e-30 Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B) Rattus norvegicus (Rat) CDP-choline pathway [GO:0006657]; ovarian follicle development [GO:0001541]; phosphatidylcholine biosynthetic process [GO:0006656]; response to vasopressin [GO:1904116]; spermatogenesis [GO:0007283] GO:0001541; GO:0004105; GO:0005783; GO:0006656; GO:0006657; GO:0007283; GO:0031210; GO:1904116 7067 FUN_005107 117 44 99 111 48 NA NA NA NA NA NA NA 7068 FUN_041702 1803 1447 843 1392 935 NA NA NA NA NA NA NA 7069 FUN_005105 447 322 111 379 192 NA NA NA NA NA NA NA 7070 FUN_005102 78 20 103 145 140 ntLink_8:31067414-31070853 P13705 6.65e-23 DNA mismatch repair protein Msh3 (Protein repair-1) (REP-1) (Protein repair-3) (REP-3) Mus musculus (Mouse) DNA repair [GO:0006281]; maintenance of DNA repeat elements [GO:0043570]; mismatch repair [GO:0006298]; mitotic recombination [GO:0006312]; negative regulation of DNA recombination [GO:0045910]; positive regulation of helicase activity [GO:0051096]; somatic recombination of immunoglobulin gene segments [GO:0016447] GO:0003677; GO:0003684; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0006281; GO:0006298; GO:0006312; GO:0016447; GO:0019237; GO:0019899; GO:0030983; GO:0032139; GO:0032142; GO:0032181; GO:0032302; GO:0043570; GO:0045910; GO:0051096; GO:0140664 7071 FUN_041705 51846 74394 42595 60680 41561 NA NA NA NA NA NA NA 7072 FUN_005100 1464 1889 773 1614 1196 NA NA NA NA NA NA NA 7073 FUN_041707 100 0 67 142 84 NA NA NA NA NA NA NA 7074 FUN_041708 303 40 113 440 218 NA NA NA NA NA NA NA 7075 FUN_041709 376 201 281 413 613 NA NA NA NA NA NA NA 7076 FUN_005108 1780 398 427 680 775 ntLink_8:31130861-31132778 Q9N0A6 3.61e-25 Repulsive guidance molecule A (RGM domain family member A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005886 7077 FUN_005109 179 86 77 80 55 NA NA NA NA NA NA NA 7078 FUN_029467 0 137 70 21 0 NA NA NA NA NA NA NA 7079 FUN_029466 3 414 33 91 27 NA NA NA NA NA NA NA 7080 FUN_012746 0 0 9 0 0 NA NA NA NA NA NA NA 7081 FUN_029464 744 1231 363 640 339 NA NA NA NA NA NA NA 7082 FUN_012740 745 450 247 378 558 NA NA NA NA NA NA NA 7083 FUN_012741 1040 760 636 1258 700 NA NA NA NA NA NA NA 7084 FUN_032908 1237 1310 958 878 897 NA NA NA NA NA NA NA 7085 FUN_032909 91 38 36 133 169 NA NA NA NA NA NA NA 7086 FUN_032904 118 79 96 122 125 NA NA NA NA NA NA NA 7087 FUN_032905 61 51 65 74 121 NA NA NA NA NA NA NA 7088 FUN_032906 3183 1944 1807 3051 2469 ptg000023l:37504326-37525047 Q8TB72 7.84e-54 Pumilio homolog 2 (Pumilio-2) Homo sapiens (Human) adipose tissue development [GO:0060612]; chromosome organization [GO:0051276]; hair follicle development [GO:0001942]; miRNA processing [GO:0035196]; mitochondrion organization [GO:0007005]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; respiratory electron transport chain [GO:0022904]; skeletal system development [GO:0001501]; stress granule assembly [GO:0034063] GO:0001501; GO:0001942; GO:0003723; GO:0003729; GO:0003730; GO:0005737; GO:0005829; GO:0006417; GO:0007005; GO:0010494; GO:0010608; GO:0022904; GO:0031965; GO:0034063; GO:0035196; GO:0035198; GO:0043488; GO:0048471; GO:0051276; GO:0051983; GO:0060612; GO:0060964; GO:0062104; GO:0106222; GO:1900246; GO:2000637 7089 FUN_032906 3183 1944 1807 3051 2469 ptg000023l:37504326-37525047 Q8TB72 4e-32 Pumilio homolog 2 (Pumilio-2) Homo sapiens (Human) adipose tissue development [GO:0060612]; chromosome organization [GO:0051276]; hair follicle development [GO:0001942]; miRNA processing [GO:0035196]; mitochondrion organization [GO:0007005]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; respiratory electron transport chain [GO:0022904]; skeletal system development [GO:0001501]; stress granule assembly [GO:0034063] GO:0001501; GO:0001942; GO:0003723; GO:0003729; GO:0003730; GO:0005737; GO:0005829; GO:0006417; GO:0007005; GO:0010494; GO:0010608; GO:0022904; GO:0031965; GO:0034063; GO:0035196; GO:0035198; GO:0043488; GO:0048471; GO:0051276; GO:0051983; GO:0060612; GO:0060964; GO:0062104; GO:0106222; GO:1900246; GO:2000637 7090 FUN_032906 3183 1944 1807 3051 2469 ptg000023l:37504326-37525047 Q8TB72 7.57e-25 Pumilio homolog 2 (Pumilio-2) Homo sapiens (Human) adipose tissue development [GO:0060612]; chromosome organization [GO:0051276]; hair follicle development [GO:0001942]; miRNA processing [GO:0035196]; mitochondrion organization [GO:0007005]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of RIG-I signaling pathway [GO:1900246]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of chromosome segregation [GO:0051983]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of mRNA stability [GO:0043488]; regulation of translation [GO:0006417]; respiratory electron transport chain [GO:0022904]; skeletal system development [GO:0001501]; stress granule assembly [GO:0034063] GO:0001501; GO:0001942; GO:0003723; GO:0003729; GO:0003730; GO:0005737; GO:0005829; GO:0006417; GO:0007005; GO:0010494; GO:0010608; GO:0022904; GO:0031965; GO:0034063; GO:0035196; GO:0035198; GO:0043488; GO:0048471; GO:0051276; GO:0051983; GO:0060612; GO:0060964; GO:0062104; GO:0106222; GO:1900246; GO:2000637 7091 FUN_012743 0 0 7 10 44 NA NA NA NA NA NA NA 7092 FUN_032902 9 198 75 160 121 NA NA NA NA NA NA NA 7093 FUN_032903 1409 506 713 1111 1309 NA NA NA NA NA NA NA 7094 FUN_006976 155 103 1502 3869 457 ptg000001l:18925112-18938389 Q9U6Y6 7.12e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 7095 FUN_006976 155 103 1502 3869 457 ptg000001l:18925112-18938389 Q9U6Y6 2.01e-27 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 7096 FUN_006976 155 103 1502 3869 457 ptg000001l:18925112-18938389 Q9U6Y6 8.47e-26 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 7097 FUN_006976 155 103 1502 3869 457 ptg000001l:18925112-18938389 Q9U6Y6 8.95e-25 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 7098 FUN_012749 68 78 41 47 57 ptg000008l:12118398-12141406 P04323 5.08e-49 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 7099 FUN_012749 68 78 41 47 57 ptg000008l:12118398-12141406 P04323 5.08e-49 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 7100 FUN_006974 0 0 10 0 13 NA NA NA NA NA NA NA 7101 FUN_006975 370 653 1124 3372 639 ptg000001l:18916445-18924522 Q9U6Y6 1.19e-27 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 7102 FUN_006975 370 653 1124 3372 639 ptg000001l:18916445-18924522 Q9U6Y6 1.11e-25 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 7103 FUN_000200 109 0 0 20 61 NA NA NA NA NA NA NA 7104 FUN_040071 1253 896 925 1385 1174 ptg000031l:3847107-3854364 P17439 1.33e-50 Lysosomal acid glucosylceramidase (Lysosomal acid GCase) (EC 3.2.1.45) (Acid beta-glucosidase) (Beta-glucocerebrosidase) (Cholesterol glucosyltransferase) (SGTase) (EC 2.4.1.-) (Cholesteryl-beta-glucosidase) (EC 3.2.1.-) (D-glucosyl-N-acylsphingosine glucohydrolase) (Lysosomal cholesterol glycosyltransferase) (Lysosomal galactosylceramidase) (EC 3.2.1.46) (Lysosomal glycosylceramidase) Mus musculus (Mouse) antigen processing and presentation [GO:0019882]; autophagosome organization [GO:1905037]; autophagy [GO:0006914]; beta-glucoside catabolic process [GO:1901805]; brain morphogenesis [GO:0048854]; cell maturation [GO:0048469]; cellular response to starvation [GO:0009267]; cellular response to tumor necrosis factor [GO:0071356]; central nervous system development [GO:0007417]; ceramide biosynthetic process [GO:0046513]; cerebellar Purkinje cell layer formation [GO:0021694]; cholesterol metabolic process [GO:0008203]; determination of adult lifespan [GO:0008340]; glucosylceramide catabolic process [GO:0006680]; glucosylceramide metabolic process [GO:0006678]; hematopoietic stem cell proliferation [GO:0071425]; homeostasis of number of cells [GO:0048872]; lipid glycosylation [GO:0030259]; lipid storage [GO:0019915]; lymphocyte migration [GO:0072676]; lysosome organization [GO:0007040]; microglia differentiation [GO:0014004]; microglial cell proliferation [GO:0061518]; mitochondrion organization [GO:0007005]; mitophagy [GO:0000423]; motor behavior [GO:0061744]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of protein metabolic process [GO:0051248]; negative regulation of protein-containing complex assembly [GO:0031333]; nervous system process [GO:0050877]; neuromuscular process [GO:0050905]; neuron apoptotic process [GO:0051402]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of neuronal action potential [GO:1904457]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein lipidation [GO:1903061]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein-containing complex disassembly [GO:0043243]; positive regulation of proteolysis involved in protein catabolic process [GO:1903052]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; pyramidal neuron differentiation [GO:0021859]; regulation of membrane potential [GO:0042391]; regulation of protein metabolic process [GO:0051246]; regulation of TOR signaling [GO:0032006]; regulation of water loss via skin [GO:0033561]; respiratory electron transport chain [GO:0022904]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to pH [GO:0009268]; response to testosterone [GO:0033574]; response to thyroid hormone [GO:0097066]; skin morphogenesis [GO:0043589]; sphingosine biosynthetic process [GO:0046512]; T cell differentiation in thymus [GO:0033077]; termination of signal transduction [GO:0023021] GO:0000423; GO:0004336; GO:0004348; GO:0005102; GO:0005124; GO:0005615; GO:0005764; GO:0005765; GO:0005783; GO:0005794; GO:0005802; GO:0006678; GO:0006680; GO:0006914; GO:0007005; GO:0007040; GO:0007417; GO:0008203; GO:0008340; GO:0008422; GO:0009267; GO:0009268; GO:0014004; GO:0016787; GO:0019882; GO:0019915; GO:0021694; GO:0021859; GO:0022904; GO:0023021; GO:0030259; GO:0031333; GO:0032006; GO:0032436; GO:0032715; GO:0033077; GO:0033561; GO:0033574; GO:0035307; GO:0042391; GO:0043161; GO:0043202; GO:0043243; GO:0043407; GO:0043524; GO:0043589; GO:0043627; GO:0046512; GO:0046513; GO:0046527; GO:0048469; GO:0048854; GO:0048872; GO:0050295; GO:0050877; GO:0050905; GO:0051246; GO:0051247; GO:0051248; GO:0051402; GO:0061518; GO:0061744; GO:0071356; GO:0071425; GO:0071548; GO:0072676; GO:0097066; GO:1901215; GO:1901805; GO:1903052; GO:1903061; GO:1904457; GO:1904925; GO:1905037 7105 FUN_003624 104 28 67 42 51 NA NA NA NA NA NA NA 7106 FUN_003622 126 51 98 100 8 NA NA NA NA NA NA NA 7107 FUN_040078 61 45 51 182 164 NA NA NA NA NA NA NA 7108 FUN_003629 18 131 15 0 31 ntLink_8:13749031-13749346 Q15485 2.22e-29 Ficolin-2 (37 kDa elastin-binding protein) (Collagen/fibrinogen domain-containing protein 2) (EBP-37) (Ficolin-B) (Ficolin-beta) (Hucolin) (L-ficolin) (Serum lectin p35) Homo sapiens (Human) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; opsonization [GO:0008228]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005576; GO:0005581; GO:0005615; GO:0006508; GO:0008228; GO:0009897; GO:0042802; GO:0043394; GO:0043654; GO:0046872; GO:0048306; GO:0050829; GO:0050830; GO:0062023; GO:0070062; GO:0072562; GO:0097367; GO:1903028; GO:1905370; GO:2001065 7109 FUN_003628 16 23 0 4 4 NA NA NA NA NA NA NA 7110 FUN_004761 10960 2129 622 2542 2449 NA NA NA NA NA NA NA 7111 FUN_010689 3187 3742 1056 2310 1477 ptg000007l:1591570-1623502 E7FAM5 2.68e-87 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 7112 FUN_010689 3187 3742 1056 2310 1477 ptg000007l:1591570-1623502 E7FAM5 4.29e-87 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 7113 FUN_010689 3187 3742 1056 2310 1477 ptg000007l:1591570-1623502 E7FAM5 2.11e-80 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 7114 FUN_010688 1798 2405 1237 1488 956 ptg000007l:1580189-1581068 P40639 2.77e-31 SRY-related protein AES4 Alligator mississippiensis (American alligator) NA GO:0003677; GO:0005634 7115 FUN_004760 8290 1668 623 2843 1881 NA NA NA NA NA NA NA 7116 FUN_010683 1026 1024 813 933 1049 NA NA NA NA NA NA NA 7117 FUN_010682 7195 7221 3882 8359 6304 NA NA NA NA NA NA NA 7118 FUN_010681 2495 1850 1440 3407 2871 NA NA NA NA NA NA NA 7119 FUN_010680 779 231 263 453 307 NA NA NA NA NA NA NA 7120 FUN_028334 0 0 0 68 0 NA NA NA NA NA NA NA 7121 FUN_010685 553 410 783 502 359 ptg000007l:1549143-1550409 Q8HYJ7 9.61e-41 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 7122 FUN_004762 113 21 16 61 74 NA NA NA NA NA NA NA 7123 FUN_004767 1659 893 759 1476 992 NA NA NA NA NA NA NA 7124 FUN_002578 287 74 102 85 404 ntLink_8:3957184-3961903 P36423 9.2e-39 Thromboxane-A synthase (TS) (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) Mus musculus (Mouse) cellular chloride ion homeostasis [GO:0030644]; icosanoid metabolic process [GO:0006690]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542] GO:0001516; GO:0004497; GO:0004796; GO:0005506; GO:0005783; GO:0005789; GO:0005829; GO:0006690; GO:0016705; GO:0020037; GO:0030644; GO:0036134; GO:0045471; GO:0045907; GO:0070542; GO:0106256 7125 FUN_002579 387 49 104 241 388 ntLink_8:3966568-3976202 P36423 2.27e-40 Thromboxane-A synthase (TS) (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) Mus musculus (Mouse) cellular chloride ion homeostasis [GO:0030644]; icosanoid metabolic process [GO:0006690]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542] GO:0001516; GO:0004497; GO:0004796; GO:0005506; GO:0005783; GO:0005789; GO:0005829; GO:0006690; GO:0016705; GO:0020037; GO:0030644; GO:0036134; GO:0045471; GO:0045907; GO:0070542; GO:0106256 7126 FUN_002579 387 49 104 241 388 ntLink_8:3966568-3976202 P36423 1.27e-39 Thromboxane-A synthase (TS) (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) Mus musculus (Mouse) cellular chloride ion homeostasis [GO:0030644]; icosanoid metabolic process [GO:0006690]; positive regulation of vasoconstriction [GO:0045907]; prostaglandin biosynthetic process [GO:0001516]; response to ethanol [GO:0045471]; response to fatty acid [GO:0070542] GO:0001516; GO:0004497; GO:0004796; GO:0005506; GO:0005783; GO:0005789; GO:0005829; GO:0006690; GO:0016705; GO:0020037; GO:0030644; GO:0036134; GO:0045471; GO:0045907; GO:0070542; GO:0106256 7127 FUN_002572 426 23 23 63 60 NA NA NA NA NA NA NA 7128 FUN_002573 273 194 22 68 57 NA NA NA NA NA NA NA 7129 FUN_002570 0 6 3 54 5 NA NA NA NA NA NA NA 7130 FUN_002576 4813 4680 4675 7603 8953 NA NA NA NA NA NA NA 7131 FUN_002577 3015 1514 950 1260 768 NA NA NA NA NA NA NA 7132 FUN_002574 937 727 123 1476 862 ntLink_8:3880349-3905070 Q8R151 8.97e-89 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 7133 FUN_002574 937 727 123 1476 862 ntLink_8:3880349-3905070 Q8R151 1.86e-73 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 7134 FUN_002574 937 727 123 1476 862 ntLink_8:3880349-3905070 Q8R151 2.37e-42 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 7135 FUN_002574 937 727 123 1476 862 ntLink_8:3880349-3905070 Q8R151 2.33e-37 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 7136 FUN_002575 7 0 0 167 51 NA NA NA NA NA NA NA 7137 FUN_011086 63 5 8 88 3 NA NA NA NA NA NA NA 7138 FUN_011087 52 4 12 75 6 NA NA NA NA NA NA NA 7139 FUN_011082 0 0 0 0 33 NA NA NA NA NA NA NA 7140 FUN_011083 0 0 3 8 38 NA NA NA NA NA NA NA 7141 FUN_012263 7455 5041 4477 9847 4193 NA NA NA NA NA NA NA 7142 FUN_012262 871 540 479 496 520 NA NA NA NA NA NA NA 7143 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 2.18e-46 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7144 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 2.45e-40 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7145 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 1.38e-38 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7146 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 8.13e-31 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7147 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 3.51e-29 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7148 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 1.09e-28 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7149 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 1.45e-28 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7150 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 4.27e-28 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7151 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 5.64e-23 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7152 FUN_012261 1791 1098 1035 2516 2050 ptg000008l:6948375-6983698 E1BNG3 2.41e-21 Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) Bos taurus (Bovine) cell population proliferation [GO:0008283]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA duplex unwinding [GO:0032508]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0003676; GO:0005524; GO:0005634; GO:0005829; GO:0006307; GO:0008283; GO:0016607; GO:0016887; GO:0032508; GO:0043138; GO:0072344; GO:0099053; GO:1990116; GO:1990391 7153 FUN_012260 0 0 0 0 16 NA NA NA NA NA NA NA 7154 FUN_012266 4476 3325 2421 4953 3172 ptg000008l:7024741-7049732 Q921C3 1.92e-23 Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0007010; GO:0008360 7155 FUN_012266 4476 3325 2421 4953 3172 ptg000008l:7024741-7049732 Q921C3 1.92e-23 Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9) Mus musculus (Mouse) cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006357; GO:0007010; GO:0008360 7156 FUN_011088 0 0 0 0 19 NA NA NA NA NA NA NA 7157 FUN_010920 9422 12895 6111 13306 13623 ptg000007l:4258143-4271174 O35643 2.03e-36 AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; clathrin coat assembly [GO:0048268]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0001822; GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007368; GO:0007507; GO:0016192; GO:0019901; GO:0030121; GO:0030276; GO:0032588; GO:0043231; GO:0048268; GO:0060155; GO:0110010; GO:0120283; GO:1903232 7158 FUN_010920 9422 12895 6111 13306 13623 ptg000007l:4258143-4271174 O35643 1.03e-27 AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; clathrin coat assembly [GO:0048268]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0001822; GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007368; GO:0007507; GO:0016192; GO:0019901; GO:0030121; GO:0030276; GO:0032588; GO:0043231; GO:0048268; GO:0060155; GO:0110010; GO:0120283; GO:1903232 7159 FUN_010920 9422 12895 6111 13306 13623 ptg000007l:4258143-4271174 O35643 1.03e-27 AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; clathrin coat assembly [GO:0048268]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0001822; GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007368; GO:0007507; GO:0016192; GO:0019901; GO:0030121; GO:0030276; GO:0032588; GO:0043231; GO:0048268; GO:0060155; GO:0110010; GO:0120283; GO:1903232 7160 FUN_010920 9422 12895 6111 13306 13623 ptg000007l:4258143-4271174 O35643 1.03e-27 AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; clathrin coat assembly [GO:0048268]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0001822; GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007368; GO:0007507; GO:0016192; GO:0019901; GO:0030121; GO:0030276; GO:0032588; GO:0043231; GO:0048268; GO:0060155; GO:0110010; GO:0120283; GO:1903232 7161 FUN_010920 9422 12895 6111 13306 13623 ptg000007l:4258143-4271174 O35643 4.78e-25 AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit) Mus musculus (Mouse) basolateral protein secretion [GO:0110010]; clathrin coat assembly [GO:0048268]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; kidney development [GO:0001822]; melanosome assembly [GO:1903232]; platelet dense granule organization [GO:0060155]; vesicle-mediated transport [GO:0016192] GO:0001822; GO:0005765; GO:0005769; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007368; GO:0007507; GO:0016192; GO:0019901; GO:0030121; GO:0030276; GO:0032588; GO:0043231; GO:0048268; GO:0060155; GO:0110010; GO:0120283; GO:1903232 7162 FUN_043039 0 10 0 0 16 NA NA NA NA NA NA NA 7163 FUN_043031 900 447 227 779 765 NA NA NA NA NA NA NA 7164 FUN_043037 413 151 315 315 278 NA NA NA NA NA NA NA 7165 FUN_012199 63 0 194 296 14 NA NA NA NA NA NA NA 7166 FUN_012195 52 836 155 298 11 NA NA NA NA NA NA NA 7167 FUN_012194 3305 1604 1336 2072 825 NA NA NA NA NA NA NA 7168 FUN_012197 213 328 41 169 231 NA NA NA NA NA NA NA 7169 FUN_012196 0 219 10 91 0 NA NA NA NA NA NA NA 7170 FUN_012191 172 174 95 136 282 NA NA NA NA NA NA NA 7171 FUN_012190 905 473 456 958 906 NA NA NA NA NA NA NA 7172 FUN_012193 606 2271 526 689 460 NA NA NA NA NA NA NA 7173 FUN_012192 6404 5068 4748 7194 5915 NA NA NA NA NA NA NA 7174 FUN_014690 4421 2413 2654 4532 5319 ptg000009l:2136815-2157510 Q8NFA0 7.63e-24 Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.4.19.12) (Deubiquitinating enzyme 32) (Renal carcinoma antigen NY-REN-60) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005509; GO:0005794; GO:0005829; GO:0006511; GO:0016020; GO:0016579 7175 FUN_014691 9 0 16 0 159 NA NA NA NA NA NA NA 7176 FUN_014692 0 8 3 0 0 NA NA NA NA NA NA NA 7177 FUN_014693 1732 1154 795 1535 1316 ptg000009l:2212182-2216644 Q9NWM3 7.56e-34 CUE domain-containing protein 1 Homo sapiens (Human) NA GO:0043130 7178 FUN_014694 441 567 377 481 459 NA NA NA NA NA NA NA 7179 FUN_014695 206 74 57 117 144 NA NA NA NA NA NA NA 7180 FUN_014696 3830 2085 68 142 1052 NA NA NA NA NA NA NA 7181 FUN_014697 3 2 2 2 7 NA NA NA NA NA NA NA 7182 FUN_014698 460 767 254 274 109 NA NA NA NA NA NA NA 7183 FUN_014699 12 79 78 181 111 NA NA NA NA NA NA NA 7184 FUN_010926 118 29 56 203 128 ptg000007l:4356948-4363444 A4IGL7 3.15e-26 Peroxidasin (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0005576; GO:0005604; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0031012; GO:0042744; GO:0046872; GO:0051260; GO:0070207; GO:0070831; GO:0071711; GO:0140825 7185 FUN_041555 3313 1439 1377 2672 2706 NA NA NA NA NA NA NA 7186 FUN_009668 880 500 603 524 559 NA NA NA NA NA NA NA 7187 FUN_009663 35 0 19 4 81 NA NA NA NA NA NA NA 7188 FUN_009662 5 0 42 0 71 NA NA NA NA NA NA NA 7189 FUN_009661 2906 2764 2006 2958 2312 NA NA NA NA NA NA NA 7190 FUN_009660 1174 693 497 801 752 NA NA NA NA NA NA NA 7191 FUN_009667 194 263 153 70 29 NA NA NA NA NA NA NA 7192 FUN_009666 1769 2942 676 87 710 ptg000004l:10131514-10145229 P0CT39 5.5e-54 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 7193 FUN_009666 1769 2942 676 87 710 ptg000004l:10131514-10145229 P0CT39 5.5e-54 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 7194 FUN_010927 32 35 24 1 6 NA NA NA NA NA NA NA 7195 FUN_041554 1290 716 381 1098 770 NA NA NA NA NA NA NA 7196 FUN_029527 10 0 2 8 10 NA NA NA NA NA NA NA 7197 FUN_029524 5677 3062 1794 2305 2061 NA NA NA NA NA NA NA 7198 FUN_029525 719 442 260 485 377 NA NA NA NA NA NA NA 7199 FUN_029523 0 0 39 17 44 NA NA NA NA NA NA NA 7200 FUN_029520 536 1136 547 531 360 NA NA NA NA NA NA NA 7201 FUN_029521 1028 272 156 660 672 NA NA NA NA NA NA NA 7202 FUN_029528 45 7 14 75 9 NA NA NA NA NA NA NA 7203 FUN_029529 0 0 0 11 9 NA NA NA NA NA NA NA 7204 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 4.55e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7205 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 1.77e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7206 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 6.54e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7207 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 1.91e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7208 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 8e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7209 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 4.9e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7210 FUN_009598 357 0 7 85 211 ptg000004l:9119735-9123173 Q96AY4 8.94e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7211 FUN_009594 38 0 39 40 13 ptg000004l:9059407-9068684 Q96AY4 2.18e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7212 FUN_009594 38 0 39 40 13 ptg000004l:9059407-9068684 Q96AY4 1.01e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7213 FUN_009594 38 0 39 40 13 ptg000004l:9059407-9068684 Q96AY4 2.71e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7214 FUN_009594 38 0 39 40 13 ptg000004l:9059407-9068684 Q96AY4 1.44e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7215 FUN_009594 38 0 39 40 13 ptg000004l:9059407-9068684 Q96AY4 6.89e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7216 FUN_009597 15 10 2 2 3 NA NA NA NA NA NA NA 7217 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 2.13e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7218 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 4.96e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7219 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 1.07e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7220 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 5.63e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7221 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 3.27e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7222 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 3.27e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7223 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 4.42e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7224 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 3.24e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7225 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 2.48e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7226 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 1.4e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7227 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 5.77e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7228 FUN_009591 15 0 0 13 8 ptg000004l:9035227-9038659 Q96AY4 1.61e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7229 FUN_009590 179 110 81 40 74 NA NA NA NA NA NA NA 7230 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 4.25e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7231 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 1.06e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7232 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 4.96e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7233 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 3.18e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7234 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 2e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7235 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 1.23e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7236 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 9.54e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7237 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 1.08e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7238 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 8.88e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7239 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 6.12e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7240 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 3.21e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7241 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 4.41e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7242 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 3.17e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7243 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 3.4e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7244 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 2.49e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7245 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 3.34e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7246 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 2.07e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7247 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 1.49e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7248 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 5.92e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7249 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 1.78e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7250 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 2.46e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7251 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 5.33e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7252 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 6.39e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7253 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 4.79e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7254 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 8.24e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7255 FUN_009592 0 0 7 3 0 ptg000004l:9046012-9049467 Q96AY4 1.24e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7256 FUN_038994 0 8 6 0 0 NA NA NA NA NA NA NA 7257 FUN_016029 85 19 0 124 33 NA NA NA NA NA NA NA 7258 FUN_042348 6 0 0 0 0 NA NA NA NA NA NA NA 7259 FUN_042341 0 0 17 0 10 NA NA NA NA NA NA NA 7260 FUN_016023 6382 2769 2005 5924 3717 NA NA NA NA NA NA NA 7261 FUN_016022 32 42 32 332 169 NA NA NA NA NA NA NA 7262 FUN_016024 166 416 173 178 101 NA NA NA NA NA NA NA 7263 FUN_016585 2599 1300 1435 1958 1415 ptg000011l:5009312-5025148 Q11011 9.79e-27 Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006; GO:0071456 7264 FUN_016585 2599 1300 1435 1958 1415 ptg000011l:5009312-5025148 Q11011 9.79e-27 Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006; GO:0071456 7265 FUN_016585 2599 1300 1435 1958 1415 ptg000011l:5009312-5025148 Q11011 2.27e-25 Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008270; GO:0042277; GO:0043171; GO:0070006; GO:0071456 7266 FUN_026278 78 92 53 69 21 NA NA NA NA NA NA NA 7267 FUN_026273 304 60 134 170 69 NA NA NA NA NA NA NA 7268 FUN_026272 6 21 9 310 0 NA NA NA NA NA NA NA 7269 FUN_026271 12 20 0 65 0 NA NA NA NA NA NA NA 7270 FUN_026270 148 0 93 0 87 ptg000020l:6993389-7011221 Q60431 1.1e-29 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 7271 FUN_026277 57 6 44 26 28 ptg000020l:7098850-7101744 P16157 2.89e-53 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7272 FUN_026277 57 6 44 26 28 ptg000020l:7098850-7101744 P16157 6.6e-52 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7273 FUN_026277 57 6 44 26 28 ptg000020l:7098850-7101744 P16157 2.17e-50 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7274 FUN_026277 57 6 44 26 28 ptg000020l:7098850-7101744 P16157 1.65e-30 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7275 FUN_026276 3 59 0 98 10 NA NA NA NA NA NA NA 7276 FUN_026275 164 18 24 109 29 NA NA NA NA NA NA NA 7277 FUN_026274 558 55 105 166 0 ptg000020l:7055077-7057293 P16157 6.15e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7278 FUN_026274 558 55 105 166 0 ptg000020l:7055077-7057293 P16157 5.12e-36 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7279 FUN_026274 558 55 105 166 0 ptg000020l:7055077-7057293 P16157 7.29e-36 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7280 FUN_026274 558 55 105 166 0 ptg000020l:7055077-7057293 P16157 4.25e-31 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7281 FUN_026274 558 55 105 166 0 ptg000020l:7055077-7057293 P16157 2.94e-28 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7282 FUN_026274 558 55 105 166 0 ptg000020l:7055077-7057293 P16157 1.82e-27 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 7283 FUN_022198 352 145 333 168 326 NA NA NA NA NA NA NA 7284 FUN_022199 61955 21400 26140 102912 84048 NA NA NA NA NA NA NA 7285 FUN_022192 213 323 95 1013 166 NA NA NA NA NA NA NA 7286 FUN_022193 238 350 84 1077 155 NA NA NA NA NA NA NA 7287 FUN_022190 319 670 214 686 411 NA NA NA NA NA NA NA 7288 FUN_022191 204 195 97 125 118 ptg000016l:6139008-6144713 Q96PQ6 1.43e-22 Zinc finger protein 317 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 7289 FUN_022196 326 53 88 203 139 NA NA NA NA NA NA NA 7290 FUN_022197 2773 2026 1569 2237 1955 NA NA NA NA NA NA NA 7291 FUN_022194 552 671 243 2457 304 NA NA NA NA NA NA NA 7292 FUN_022195 21037 23788 12416 14052 9025 ptg000016l:6173744-6177800 P17220 3.38e-24 Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3) Rattus norvegicus (Rat) proteasomal protein catabolic process [GO:0010498]; response to virus [GO:0009615]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0005634; GO:0005737; GO:0005839; GO:0006511; GO:0009615; GO:0010498; GO:0019773 7293 FUN_040255 0 0 106 13 13 ptg000031l:5957541-5960459 P47970 3.23e-26 Neuronal pentraxin-2 (NP2) (Acrosomal pentaxin-like protein p50) (AM50) (Neuronal pentraxin II) (Apexin) (NP-II) Cavia porcellus (Guinea pig) NA GO:0043160; GO:0046872 7294 FUN_017646 0 0 0 9 8 NA NA NA NA NA NA NA 7295 FUN_041552 1552 585 374 772 671 ptg000035l:5080724-5087691 Q6DF08 3.92e-26 UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) D-xylose metabolic process [GO:0042732]; UDP-D-xylose biosynthetic process [GO:0033320] GO:0032580; GO:0033320; GO:0042732; GO:0048040; GO:0070403 7296 FUN_041552 1552 585 374 772 671 ptg000035l:5080724-5087691 Q6DF08 3.92e-26 UDP-glucuronic acid decarboxylase 1 (EC 4.1.1.35) (UDP-glucuronate decarboxylase 1) (UXS-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) D-xylose metabolic process [GO:0042732]; UDP-D-xylose biosynthetic process [GO:0033320] GO:0032580; GO:0033320; GO:0042732; GO:0048040; GO:0070403 7297 FUN_023579 1894 2327 1271 3319 2449 NA NA NA NA NA NA NA 7298 FUN_023578 2347 2447 2740 6455 2091 ptg000017l:9494807-9505864 O95786 6.34e-29 Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I) Homo sapiens (Human) antiviral innate immune response [GO:0140374]; cellular response to exogenous dsRNA [GO:0071360]; cytosolic pattern recognition receptor signaling pathway [GO:0002753]; defense response to virus [GO:0051607]; detection of virus [GO:0009597]; gene expression [GO:0010467]; innate immune response [GO:0045087]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte macrophage colony-stimulating factor production [GO:0032725]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of myeloid dendritic cell cytokine production [GO:0002735]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell migration [GO:0030334]; regulation of type III interferon production [GO:0034344]; response to exogenous dsRNA [GO:0043330]; response to virus [GO:0009615]; RIG-I signaling pathway [GO:0039529] GO:0002230; GO:0002735; GO:0002753; GO:0003690; GO:0003724; GO:0003725; GO:0003727; GO:0005524; GO:0005525; GO:0005737; GO:0005829; GO:0005923; GO:0008270; GO:0009597; GO:0009615; GO:0010467; GO:0010628; GO:0015629; GO:0016887; GO:0030334; GO:0031625; GO:0032587; GO:0032725; GO:0032727; GO:0032728; GO:0032755; GO:0032757; GO:0032760; GO:0034344; GO:0039529; GO:0042802; GO:0043330; GO:0045087; GO:0045944; GO:0051091; GO:0051607; GO:0060760; GO:0071360; GO:0140374; GO:1990904 7299 FUN_023577 432 355 266 380 342 ptg000017l:9478690-9493216 E1BGQ2 7.77e-21 rRNA N6-adenosine-methyltransferase ZCCHC4 (EC 2.1.1.-) (Zinc finger CCHC domain-containing protein 4) Bos taurus (Bovine) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167] GO:0003676; GO:0005730; GO:0005737; GO:0008270; GO:0008988; GO:0031167; GO:0045727; GO:1904047 7300 FUN_023576 409 634 518 380 419 NA NA NA NA NA NA NA 7301 FUN_023575 103 235 122 131 122 ptg000017l:9435097-9462693 B3LVW5 5.56e-31 cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) Drosophila ananassae (Fruit fly) cGMP metabolic process [GO:0046068]; signal transduction [GO:0007165] GO:0005634; GO:0005737; GO:0005886; GO:0007165; GO:0016020; GO:0046068; GO:0046872; GO:0047555 7302 FUN_023574 27 0 13 0 69 NA NA NA NA NA NA NA 7303 FUN_023573 27 0 0 0 31 NA NA NA NA NA NA NA 7304 FUN_023572 0 0 8 0 0 NA NA NA NA NA NA NA 7305 FUN_023571 18 0 0 57 20 NA NA NA NA NA NA NA 7306 FUN_023570 0 16 11 33 62 NA NA NA NA NA NA NA 7307 FUN_022228 0 13 17 67 39 NA NA NA NA NA NA NA 7308 FUN_022229 0 15 19 62 39 NA NA NA NA NA NA NA 7309 FUN_022224 827 875 202 497 546 NA NA NA NA NA NA NA 7310 FUN_022225 257 202 114 506 318 NA NA NA NA NA NA NA 7311 FUN_022226 49 10 18 0 0 NA NA NA NA NA NA NA 7312 FUN_022220 211 86 59 102 185 ptg000016l:6453466-6454381 A7SG73 1e-137 Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) Nematostella vectensis (Starlet sea anemone) NAD biosynthetic process [GO:0009435]; quinolinate catabolic process [GO:0034213] GO:0004514; GO:0005737; GO:0009435; GO:0034213 7313 FUN_022221 22 28 31 37 29 NA NA NA NA NA NA NA 7314 FUN_022222 51 52 59 66 21 ptg000016l:6461018-6465325 P16067 3.16e-42 Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Rattus norvegicus (Rat) activation of meiosis involved in egg activation [GO:0060466]; axonogenesis [GO:0007409]; axonogenesis involved in innervation [GO:0060385]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; bone development [GO:0060348]; bone growth [GO:0098868]; c-di-GMP signaling [GO:0061939]; cartilage development [GO:0051216]; cellular response to cGMP [GO:0071321]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to peptide [GO:1901653]; cGMP biosynthetic process [GO:0006182]; cGMP metabolic process [GO:0046068]; cGMP-mediated signaling [GO:0019934]; chemical synaptic transmission [GO:0007268]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; chromosome organization [GO:0051276]; collateral sprouting [GO:0048668]; cumulus cell differentiation [GO:0001549]; digestive tract development [GO:0048565]; digestive tract morphogenesis [GO:0048546]; endochondral ossification [GO:0001958]; epidermal growth factor receptor signaling pathway [GO:0007173]; execution phase of apoptosis [GO:0097194]; female genitalia development [GO:0030540]; gastric emptying [GO:0035483]; genitalia morphogenesis [GO:0035112]; germ cell development [GO:0007281]; growth plate cartilage development [GO:0003417]; limb development [GO:0060173]; limb morphogenesis [GO:0035108]; lymph vessel development [GO:0001945]; MAPK cascade [GO:0000165]; meiotic cell cycle [GO:0051321]; meiotic cell cycle process involved in oocyte maturation [GO:1903537]; multicellular organism growth [GO:0035264]; multicellular organism reproduction [GO:0032504]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of oocyte maturation [GO:1900194]; nerve development [GO:0021675]; neuron apoptotic process [GO:0051402]; neuronal action potential [GO:0019228]; oocyte development [GO:0048599]; ovarian follicle development [GO:0001541]; positive regulation of cGMP-mediated signaling [GO:0010753]; post-anal tail morphogenesis [GO:0036342]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; reproductive process [GO:0022414]; response to fibroblast growth factor [GO:0071774]; response to hormone [GO:0009725]; response to luteinizing hormone [GO:0034699]; response to salt [GO:1902074]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; single fertilization [GO:0007338]; smooth muscle tissue development [GO:0048745]; spermatogenesis [GO:0007283]; startle response [GO:0001964]; vacuole organization [GO:0007033]; vascular wound healing [GO:0061042]; vasculogenesis [GO:0001570]; vestibulocochlear nerve development [GO:0021562]; vestibulocochlear nerve maturation [GO:0021647]; white fat cell differentiation [GO:0050872] GO:0000165; GO:0001541; GO:0001549; GO:0001568; GO:0001570; GO:0001653; GO:0001945; GO:0001958; GO:0001964; GO:0001974; GO:0002062; GO:0003417; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005634; GO:0005737; GO:0005886; GO:0005929; GO:0006182; GO:0006468; GO:0007033; GO:0007165; GO:0007168; GO:0007173; GO:0007268; GO:0007281; GO:0007283; GO:0007338; GO:0007409; GO:0007605; GO:0008015; GO:0009611; GO:0009725; GO:0010753; GO:0016941; GO:0017046; GO:0019228; GO:0019934; GO:0021562; GO:0021647; GO:0021675; GO:0022414; GO:0030540; GO:0032504; GO:0034699; GO:0035108; GO:0035112; GO:0035264; GO:0035483; GO:0035988; GO:0036342; GO:0042562; GO:0042802; GO:0043005; GO:0045202; GO:0046068; GO:0048546; GO:0048565; GO:0048599; GO:0048668; GO:0048745; GO:0050872; GO:0051216; GO:0051276; GO:0051321; GO:0051402; GO:0051447; GO:0060173; GO:0060348; GO:0060385; GO:0060466; GO:0061042; GO:0061939; GO:0071321; GO:0071774; GO:0097011; GO:0097194; GO:0098868; GO:1900194; GO:1901653; GO:1902074; GO:1903537 7315 FUN_022223 335 243 136 200 281 NA NA NA NA NA NA NA 7316 FUN_039684 27 0 0 0 40 NA NA NA NA NA NA NA 7317 FUN_018145 85 33 86 251 93 NA NA NA NA NA NA NA 7318 FUN_018148 215 72 309 528 173 NA NA NA NA NA NA NA 7319 FUN_027925 18 6 34 2 40 ptg000021l:13379712-13380156 Q1JPS6 2.37e-26 Melanopsin-like (Melanopsin) (Opsin-4-like) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; light-induced release of internally sequestered calcium ion [GO:0008377]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0008377; GO:0009881; GO:0071482 7320 FUN_019566 0 0 0 0 6 NA NA NA NA NA NA NA 7321 FUN_019561 116 66 134 306 221 NA NA NA NA NA NA NA 7322 FUN_019560 1381 827 1197 1970 1937 NA NA NA NA NA NA NA 7323 FUN_019563 247 213 313 459 282 NA NA NA NA NA NA NA 7324 FUN_034729 0 0 0 0 26 NA NA NA NA NA NA NA 7325 FUN_024103 29 19 9 14 14 NA NA NA NA NA NA NA 7326 FUN_024102 4 19 40 0 36 NA NA NA NA NA NA NA 7327 FUN_024101 41 16 33 18 27 NA NA NA NA NA NA NA 7328 FUN_024107 7572 7014 6192 5115 5594 NA NA NA NA NA NA NA 7329 FUN_024106 20 18 8 67 19 NA NA NA NA NA NA NA 7330 FUN_024105 173 561 81 296 138 NA NA NA NA NA NA NA 7331 FUN_024104 49 74 19 66 22 NA NA NA NA NA NA NA 7332 FUN_024109 268 242 159 944 451 NA NA NA NA NA NA NA 7333 FUN_024108 733 942 867 960 513 NA NA NA NA NA NA NA 7334 FUN_030670 412 468 265 498 481 NA NA NA NA NA NA NA 7335 FUN_030671 858 396 300 603 541 NA NA NA NA NA NA NA 7336 FUN_030674 5698 3650 3895 5525 5429 NA NA NA NA NA NA NA 7337 FUN_030677 238 96 182 135 109 NA NA NA NA NA NA NA 7338 FUN_030678 194 247 129 124 117 NA NA NA NA NA NA NA 7339 FUN_030679 4093 4135 1747 3124 2422 ptg000023l:14660366-14670726 Q17RD7 7.1e-27 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 7340 FUN_030679 4093 4135 1747 3124 2422 ptg000023l:14660366-14670726 Q17RD7 3.78e-22 Synaptotagmin-16 (Chr14Syt) (Synaptotagmin 14-like protein) (Synaptotagmin XIV-related protein) Homo sapiens (Human) NA GO:0005543; GO:0042802 7341 FUN_038087 563 675 766 415 459 NA NA NA NA NA NA NA 7342 FUN_038086 596 317 217 501 438 NA NA NA NA NA NA NA 7343 FUN_038085 20 43 29 36 33 NA NA NA NA NA NA NA 7344 FUN_038084 35 9 16 26 52 NA NA NA NA NA NA NA 7345 FUN_038083 0 0 0 135 0 NA NA NA NA NA NA NA 7346 FUN_038082 393 265 308 803 814 NA NA NA NA NA NA NA 7347 FUN_038081 1710 1179 912 1679 822 NA NA NA NA NA NA NA 7348 FUN_038080 1477 767 531 889 786 NA NA NA NA NA NA NA 7349 FUN_038089 1153 188 300 669 434 ptg000027l:2252413-2253073 Q5PR73 5.81e-34 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Mus musculus (Mouse) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 7350 FUN_038088 674 177 155 405 225 ptg000027l:2242826-2247177 Q02589 4.6e-58 ADP-ribosylhydrolase ARH1 (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme) ([Protein ADP-ribosylarginine] hydrolase) (ADP-ribosylarginine hydrolase) Rattus norvegicus (Rat) protein de-ADP-ribosylation [GO:0051725]; protein modification process [GO:0036211] GO:0000287; GO:0003875; GO:0005615; GO:0005829; GO:0030955; GO:0036211; GO:0051725 7351 FUN_038088 674 177 155 405 225 ptg000027l:2242826-2247177 Q02589 2.47e-24 ADP-ribosylhydrolase ARH1 (EC 3.2.2.19) (ADP-ribose-L-arginine cleaving enzyme) ([Protein ADP-ribosylarginine] hydrolase) (ADP-ribosylarginine hydrolase) Rattus norvegicus (Rat) protein de-ADP-ribosylation [GO:0051725]; protein modification process [GO:0036211] GO:0000287; GO:0003875; GO:0005615; GO:0005829; GO:0030955; GO:0036211; GO:0051725 7352 FUN_032201 597 393 411 371 460 NA NA NA NA NA NA NA 7353 FUN_027486 125 654 23 137 49 NA NA NA NA NA NA NA 7354 FUN_027485 0 0 27 0 8 NA NA NA NA NA NA NA 7355 FUN_027483 0 0 0 229 0 NA NA NA NA NA NA NA 7356 FUN_028731 3 5 26 11 20 NA NA NA NA NA NA NA 7357 FUN_036738 0 0 22 7 9 NA NA NA NA NA NA NA 7358 FUN_037464 293 224 95 144 250 NA NA NA NA NA NA NA 7359 FUN_037465 281 248 208 298 140 NA NA NA NA NA NA NA 7360 FUN_037466 284 163 57 146 93 NA NA NA NA NA NA NA 7361 FUN_037467 673 204 110 792 533 NA NA NA NA NA NA NA 7362 FUN_037460 12 9 5 12 12 NA NA NA NA NA NA NA 7363 FUN_037461 4639 3996 2111 4002 3130 NA NA NA NA NA NA NA 7364 FUN_037462 445 161 152 649 280 NA NA NA NA NA NA NA 7365 FUN_037463 226 62 88 185 152 NA NA NA NA NA NA NA 7366 FUN_037468 201 128 111 204 110 NA NA NA NA NA NA NA 7367 FUN_037469 235 802 9 480 263 NA NA NA NA NA NA NA 7368 FUN_006107 1477 1310 924 1614 1161 ptg000001l:7831948-7835519 P49116 1.59e-26 Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4) Homo sapiens (Human) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of embryonic development [GO:0040019]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0004879; GO:0005654; GO:0006355; GO:0006357; GO:0007283; GO:0007399; GO:0008270; GO:0030154; GO:0040019; GO:0043565; GO:0045944; GO:0048856; GO:1990837 7369 FUN_006106 21 50 30 112 102 NA NA NA NA NA NA NA 7370 FUN_006105 296 296 137 248 190 NA NA NA NA NA NA NA 7371 FUN_006104 708 552 291 678 526 NA NA NA NA NA NA NA 7372 FUN_006103 5 24 6 0 17 NA NA NA NA NA NA NA 7373 FUN_006102 1 0 0 1 10 NA NA NA NA NA NA NA 7374 FUN_006101 0 0 0 0 9 NA NA NA NA NA NA NA 7375 FUN_006108 338 244 301 489 368 NA NA NA NA NA NA NA 7376 FUN_001554 1575 756 428 1697 1416 ntLink_6:13697004-13715873 Q9Y5X5 4.59e-21 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 7377 FUN_001557 170 3 36 6 38 ntLink_6:13734780-13735842 P35406 8.64e-22 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 7378 FUN_011190 0 0 0 0 7 NA NA NA NA NA NA NA 7379 FUN_002680 74 16 0 224 104 NA NA NA NA NA NA NA 7380 FUN_002681 55 0 16 229 93 NA NA NA NA NA NA NA 7381 FUN_005746 0 0 0 0 86 NA NA NA NA NA NA NA 7382 FUN_005740 713 1781 809 273 113 ptg000001l:3465741-3469633 A0A1L4BJ98 1.41e-28 Dermonecrotic toxin Hl-PLD1 (EC 4.6.1.-) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Hemiscorpius lepturus (Scorpion) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 7383 FUN_005740 713 1781 809 273 113 ptg000001l:3465741-3469633 A0A1L4BJ98 1.71e-28 Dermonecrotic toxin Hl-PLD1 (EC 4.6.1.-) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Hemiscorpius lepturus (Scorpion) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 7384 FUN_005742 256 735 332 206 101 ptg000001l:3474126-3475223 A0A1L4BJ98 9.18e-30 Dermonecrotic toxin Hl-PLD1 (EC 4.6.1.-) (Phospholipase D) (PLD) (Sphingomyelin phosphodiesterase D) (SMD) (SMase D) (Sphingomyelinase D) Hemiscorpius lepturus (Scorpion) hemolysis in another organism [GO:0044179]; lipid catabolic process [GO:0016042] GO:0005576; GO:0008081; GO:0016042; GO:0016829; GO:0044179; GO:0046872; GO:0090729 7385 FUN_005743 0 0 0 0 7 NA NA NA NA NA NA NA 7386 FUN_005748 1981 1415 923 1748 1242 ptg000001l:3551290-3618636 Q09575 1.89e-40 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 7387 FUN_005749 1215 833 685 1167 894 NA NA NA NA NA NA NA 7388 FUN_001454 107 34 39 42 134 NA NA NA NA NA NA NA 7389 FUN_001455 949 617 703 1137 1245 ntLink_6:12557209-12560645 O94844 9.24e-81 Rho-related BTB domain-containing protein 1 Homo sapiens (Human) actin filament organization [GO:0007015]; cortical cytoskeleton organization [GO:0030865]; engulfment of apoptotic cell [GO:0043652]; establishment or maintenance of cell polarity [GO:0007163]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0010008; GO:0019901; GO:0030865; GO:0031410; GO:0032956; GO:0042995; GO:0043652 7390 FUN_001456 488 452 180 264 248 NA NA NA NA NA NA NA 7391 FUN_001457 240 109 118 27 14 NA NA NA NA NA NA NA 7392 FUN_001450 5 33 6 56 21 NA NA NA NA NA NA NA 7393 FUN_001451 681 311 231 649 608 NA NA NA NA NA NA NA 7394 FUN_001452 1858 1088 835 1428 1096 NA NA NA NA NA NA NA 7395 FUN_001453 69247 53932 23549 53680 23140 ntLink_6:12545729-12550169 Q9UBR2 1.69e-43 Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) Homo sapiens (Human) angiotensin maturation [GO:0002003]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of protein binding [GO:0032091]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of neuron death [GO:1901214] GO:0002003; GO:0004180; GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0005783; GO:0005788; GO:0005886; GO:0005938; GO:0006508; GO:0008234; GO:0010757; GO:0030134; GO:0031410; GO:0032091; GO:0033116; GO:0035580; GO:0043231; GO:0051603; GO:0060441; GO:0062023; GO:0070062; GO:1901214; GO:1904813 7396 FUN_001453 69247 53932 23549 53680 23140 ntLink_6:12545729-12550169 Q9UBR2 4.49e-28 Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) Homo sapiens (Human) angiotensin maturation [GO:0002003]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of protein binding [GO:0032091]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of neuron death [GO:1901214] GO:0002003; GO:0004180; GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0005783; GO:0005788; GO:0005886; GO:0005938; GO:0006508; GO:0008234; GO:0010757; GO:0030134; GO:0031410; GO:0032091; GO:0033116; GO:0035580; GO:0043231; GO:0051603; GO:0060441; GO:0062023; GO:0070062; GO:1901214; GO:1904813 7397 FUN_001453 69247 53932 23549 53680 23140 ntLink_6:12545729-12550169 Q9UBR2 6.73e-21 Cathepsin Z (EC 3.4.18.1) (Cathepsin P) (Cathepsin X) Homo sapiens (Human) angiotensin maturation [GO:0002003]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; negative regulation of plasminogen activation [GO:0010757]; negative regulation of protein binding [GO:0032091]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of neuron death [GO:1901214] GO:0002003; GO:0004180; GO:0004197; GO:0005576; GO:0005615; GO:0005764; GO:0005783; GO:0005788; GO:0005886; GO:0005938; GO:0006508; GO:0008234; GO:0010757; GO:0030134; GO:0031410; GO:0032091; GO:0033116; GO:0035580; GO:0043231; GO:0051603; GO:0060441; GO:0062023; GO:0070062; GO:1901214; GO:1904813 7398 FUN_001458 414 356 304 467 224 NA NA NA NA NA NA NA 7399 FUN_001459 1371 964 794 947 642 ntLink_6:12586278-12604578 Q5D1E7 4.01e-78 Endoribonuclease ZC3H12A (EC 3.1.-.-) (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cellular response to chemokine [GO:1990869]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; cellular response to interleukin-1 [GO:0071347]; cellular response to ionomycin [GO:1904637]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cellular response to sodium arsenite [GO:1903936]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to virus [GO:0098586]; immune response-activating signaling pathway [GO:0002757]; inflammatory response [GO:0006954]; miRNA catabolic process [GO:0010587]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of cardiac muscle contraction [GO:0055118]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of muscle cell apoptotic process [GO:0010656]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; nervous system development [GO:0007399]; nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [GO:0000294]; positive regulation of angiogenesis [GO:0045766]; positive regulation of autophagy [GO:0010508]; positive regulation of cell death [GO:0010942]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of execution phase of apoptosis [GO:1900119]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of gene expression [GO:0010628]; positive regulation of lipid storage [GO:0010884]; positive regulation of miRNA catabolic process [GO:2000627]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein deubiquitination [GO:1903003]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein complex oligomerization [GO:0051259]; protein deubiquitination [GO:0016579]; regulation of gene expression [GO:0010468]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; T cell receptor signaling pathway [GO:0050852] GO:0000294; GO:0000932; GO:0001525; GO:0001933; GO:0002230; GO:0002757; GO:0003677; GO:0003682; GO:0003723; GO:0003729; GO:0003730; GO:0004518; GO:0004521; GO:0004532; GO:0004540; GO:0004843; GO:0005634; GO:0005654; GO:0005737; GO:0005791; GO:0005856; GO:0006915; GO:0006954; GO:0006974; GO:0007399; GO:0010468; GO:0010508; GO:0010587; GO:0010595; GO:0010628; GO:0010629; GO:0010656; GO:0010884; GO:0010942; GO:0016579; GO:0030154; GO:0030867; GO:0032088; GO:0032689; GO:0032691; GO:0032715; GO:0032720; GO:0032991; GO:0034599; GO:0035198; GO:0035613; GO:0035925; GO:0036464; GO:0042149; GO:0042307; GO:0042406; GO:0043022; GO:0043124; GO:0044828; GO:0045019; GO:0045600; GO:0045766; GO:0045944; GO:0046872; GO:0050852; GO:0051259; GO:0055118; GO:0061014; GO:0061158; GO:0071222; GO:0071347; GO:0071356; GO:0090501; GO:0090502; GO:0098586; GO:1900016; GO:1900119; GO:1900745; GO:1901223; GO:1903003; GO:1903936; GO:1904637; GO:1990869; GO:2000320; GO:2000379; GO:2000627 7400 FUN_031943 1453 906 1461 1147 797 NA NA NA NA NA NA NA 7401 FUN_031942 1786 651 782 1088 1121 NA NA NA NA NA NA NA 7402 FUN_033616 0 259 3 0 98 NA NA NA NA NA NA NA 7403 FUN_033613 3061 1841 535 1650 1828 NA NA NA NA NA NA NA 7404 FUN_033611 3571 1594 158 419 2817 ptg000023l:43733811-43789454 O95071 1.8e-28 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016020; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 7405 FUN_033611 3571 1594 158 419 2817 ptg000023l:43733811-43789454 O95071 4.02e-27 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779] GO:0000209; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016020; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 7406 FUN_001213 5045 3835 2070 4622 3534 NA NA NA NA NA NA NA 7407 FUN_033619 52 0 0 0 0 NA NA NA NA NA NA NA 7408 FUN_033618 16 63 15 34 41 NA NA NA NA NA NA NA 7409 FUN_040878 1743 1262 827 1145 1167 ptg000031l:13764564-13771446 Q9VH08 1.37e-36 NAD-dependent protein deacetylase Sirt6 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 6) (dSirt6) (SIR2-like protein 6) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; determination of adult lifespan [GO:0008340]; histone H3 deacetylation [GO:0070932]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000785; GO:0003714; GO:0004407; GO:0005634; GO:0006325; GO:0008340; GO:0016746; GO:0017136; GO:0019213; GO:0046872; GO:0046969; GO:0070403; GO:0070932; GO:0090310 7410 FUN_040878 1743 1262 827 1145 1167 ptg000031l:13764564-13771446 Q9VH08 1.37e-36 NAD-dependent protein deacetylase Sirt6 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 6) (dSirt6) (SIR2-like protein 6) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; determination of adult lifespan [GO:0008340]; histone H3 deacetylation [GO:0070932]; negative regulation of DNA methylation-dependent heterochromatin formation [GO:0090310]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000785; GO:0003714; GO:0004407; GO:0005634; GO:0006325; GO:0008340; GO:0016746; GO:0017136; GO:0019213; GO:0046872; GO:0046969; GO:0070403; GO:0070932; GO:0090310 7411 FUN_001210 423 502 333 584 702 NA NA NA NA NA NA NA 7412 FUN_031331 11 0 0 6 4 NA NA NA NA NA NA NA 7413 FUN_031923 22 18 0 16 39 NA NA NA NA NA NA NA 7414 FUN_031922 343 118 62 313 107 NA NA NA NA NA NA NA 7415 FUN_031921 168 201 226 211 121 NA NA NA NA NA NA NA 7416 FUN_031920 111 57 38 66 87 NA NA NA NA NA NA NA 7417 FUN_031927 31 22 26 7 33 ptg000023l:26850130-26850982 Q9C907 7.25e-47 Glycerophosphodiester phosphodiesterase GDPD5 (EC 3.1.4.46) (Glycerophosphodiester phosphodiesterase 5) (ATGDPD5) Arabidopsis thaliana (Mouse-ear cress) glycerol metabolic process [GO:0006071]; lipid metabolic process [GO:0006629] GO:0000325; GO:0005576; GO:0005829; GO:0006071; GO:0006629; GO:0008889 7418 FUN_031926 194 144 155 139 470 NA NA NA NA NA NA NA 7419 FUN_031925 65 32 27 90 134 NA NA NA NA NA NA NA 7420 FUN_031924 4 5 6 30 4 NA NA NA NA NA NA NA 7421 FUN_031929 460 369 287 256 366 ptg000023l:26854433-26862690 A0A061IR73 3.75e-35 Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal biogenesis factor 6) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335] GO:0001750; GO:0005524; GO:0005778; GO:0005829; GO:0008022; GO:0016558; GO:0016561; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0050821; GO:0140036; GO:0140318 7422 FUN_031929 460 369 287 256 366 ptg000023l:26854433-26862690 A0A061IR73 7.66e-23 Peroxisomal ATPase PEX6 (EC 3.6.4.-) (Peroxin-6) (Peroxisomal biogenesis factor 6) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, translocation [GO:0016561]; protein stabilization [GO:0050821]; protein unfolding [GO:0043335] GO:0001750; GO:0005524; GO:0005778; GO:0005829; GO:0008022; GO:0016558; GO:0016561; GO:0016562; GO:0016887; GO:0043335; GO:0044877; GO:0050821; GO:0140036; GO:0140318 7423 FUN_031928 0 23 19 6 27 NA NA NA NA NA NA NA 7424 FUN_028942 779 644 315 177 417 NA NA NA NA NA NA NA 7425 FUN_018314 186 50 47 102 112 NA NA NA NA NA NA NA 7426 FUN_018317 132 14 30 79 43 NA NA NA NA NA NA NA 7427 FUN_034347 6 0 4 0 0 NA NA NA NA NA NA NA 7428 FUN_034340 720 525 510 557 531 ptg000024l:7858766-7866099 Q8BH18 5.35e-40 Transmembrane protein 117 Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 7429 FUN_034340 720 525 510 557 531 ptg000024l:7858766-7866099 Q8BH18 1.12e-28 Transmembrane protein 117 Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 7430 FUN_034341 337 150 101 243 143 NA NA NA NA NA NA NA 7431 FUN_034343 25 26 11 38 53 NA NA NA NA NA NA NA 7432 FUN_018318 274 25 86 144 145 NA NA NA NA NA NA NA 7433 FUN_001811 3658 4379 1658 3095 1241 NA NA NA NA NA NA NA 7434 FUN_004580 619 318 503 573 964 NA NA NA NA NA NA NA 7435 FUN_031948 0 1 0 20 15 NA NA NA NA NA NA NA 7436 FUN_004839 0 0 0 12 0 NA NA NA NA NA NA NA 7437 FUN_007867 174 82 72 160 23 NA NA NA NA NA NA NA 7438 FUN_007078 109 35 76 141 73 NA NA NA NA NA NA NA 7439 FUN_006384 6 0 43 0 64 NA NA NA NA NA NA NA 7440 FUN_043238 1118 708 374 842 400 NA NA NA NA NA NA NA 7441 FUN_043239 3425 2718 1344 2199 601 NA NA NA NA NA NA NA 7442 FUN_043236 16376 6798 6603 29371 17456 NA NA NA NA NA NA NA 7443 FUN_007075 410 291 100 180 122 ptg000001l:20140745-20148078 Q9W5Y0 1.94e-28 Neprilysin-3 (EC 3.4.24.11) Drosophila melanogaster (Fruit fly) peptide hormone processing [GO:0016486]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0004222; GO:0005886; GO:0006508; GO:0008237; GO:0016020; GO:0016485; GO:0016486; GO:0046872 7444 FUN_043234 2429 2109 1210 1875 1882 NA NA NA NA NA NA NA 7445 FUN_007077 131 48 40 33 140 ptg000001l:20153875-20155297 Q0EEE2 1.03e-43 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 7446 FUN_043232 497 277 255 424 482 ptg000047l:5672914-5691867 P48053 5.92e-27 Uncharacterized protein C05D11.1 Caenorhabditis elegans NA GO:0004222; GO:0046872 7447 FUN_043232 497 277 255 424 482 ptg000047l:5672914-5691867 P48053 5.92e-27 Uncharacterized protein C05D11.1 Caenorhabditis elegans NA GO:0004222; GO:0046872 7448 FUN_043233 2470 875 1000 1648 1441 NA NA NA NA NA NA NA 7449 FUN_043230 11531 13113 5534 14253 8599 NA NA NA NA NA NA NA 7450 FUN_007073 196 66 90 316 295 NA NA NA NA NA NA NA 7451 FUN_019048 0 2 44 9 17 NA NA NA NA NA NA NA 7452 FUN_019043 168 63 0 0 27 NA NA NA NA NA NA NA 7453 FUN_019040 0 0 10 0 0 NA NA NA NA NA NA NA 7454 FUN_019046 7 0 0 0 13 NA NA NA NA NA NA NA 7455 FUN_034838 26 25 6 18 18 NA NA NA NA NA NA NA 7456 FUN_034839 397 324 181 441 232 NA NA NA NA NA NA NA 7457 FUN_026984 2227 1490 1294 2869 2679 NA NA NA NA NA NA NA 7458 FUN_034832 1692 698 981 1234 1505 NA NA NA NA NA NA NA 7459 FUN_034833 10374 7815 6678 13654 11880 NA NA NA NA NA NA NA 7460 FUN_034830 2414 4579 1643 2134 1887 NA NA NA NA NA NA NA 7461 FUN_034831 216 119 107 114 103 NA NA NA NA NA NA NA 7462 FUN_034836 4582 2115 1490 3536 3277 NA NA NA NA NA NA NA 7463 FUN_034837 1659 842 1500 1798 1454 ptg000025l:633268-635039 Q8BH75 1.05e-35 E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1) Mus musculus (Mouse) autophagy [GO:0006914]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitophagy [GO:1901525]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; proteasomal protein catabolic process [GO:0010498]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of lymphocyte differentiation [GO:0045619]; regulation of MAPK cascade [GO:0043408]; regulation of myeloid cell differentiation [GO:0045637]; regulation of protein kinase B signaling [GO:0051896]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0000209; GO:0004842; GO:0005128; GO:0005135; GO:0006914; GO:0008270; GO:0008285; GO:0010498; GO:0016567; GO:0019904; GO:0030336; GO:0030971; GO:0031267; GO:0042802; GO:0043408; GO:0045619; GO:0045637; GO:0045732; GO:0048471; GO:0051865; GO:0051896; GO:0061630; GO:0071782; GO:0097191; GO:1901525; GO:2000377; GO:2000379 7464 FUN_034834 3086 2273 1775 3484 3187 ptg000025l:585070-598360 Q3B6R3 8.27e-25 ATP-dependent zinc metalloprotease FtsH (EC 3.4.24.-) Chlorobium luteolum (strain DSM 273 / BCRC 81028 / 2530) (Pelodictyon luteolum) protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004176; GO:0004222; GO:0005524; GO:0005886; GO:0006508; GO:0008270; GO:0016887; GO:0030163 7465 FUN_034835 7708 6532 4472 7880 6014 NA NA NA NA NA NA NA 7466 FUN_043580 1971 876 1295 1772 2111 ptg000047l:10121193-10165350 Q2TL32 1.07e-47 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Zinc finger UBR1-type protein 1) Rattus norvegicus (Rat) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0006511; GO:0008270; GO:0016020; GO:0061630 7467 FUN_043580 1971 876 1295 1772 2111 ptg000047l:10121193-10165350 Q2TL32 3.87e-40 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Zinc finger UBR1-type protein 1) Rattus norvegicus (Rat) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0006511; GO:0008270; GO:0016020; GO:0061630 7468 FUN_043580 1971 876 1295 1772 2111 ptg000047l:10121193-10165350 Q2TL32 8.42e-35 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Zinc finger UBR1-type protein 1) Rattus norvegicus (Rat) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0006511; GO:0008270; GO:0016020; GO:0061630 7469 FUN_043580 1971 876 1295 1772 2111 ptg000047l:10121193-10165350 Q2TL32 1.17e-24 E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Zinc finger UBR1-type protein 1) Rattus norvegicus (Rat) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005516; GO:0005654; GO:0005813; GO:0005829; GO:0006511; GO:0008270; GO:0016020; GO:0061630 7470 FUN_043581 392 263 183 287 259 ptg000047l:10197616-10200262 Q28DV7 2.61e-116 Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; DNA-templated DNA replication [GO:0006261]; sister chromatid cohesion [GO:0007062] GO:0003682; GO:0005634; GO:0006261; GO:0007062; GO:0051301 7471 FUN_043581 392 263 183 287 259 ptg000047l:10197616-10200262 Q28DV7 3.49e-33 Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; DNA-templated DNA replication [GO:0006261]; sister chromatid cohesion [GO:0007062] GO:0003682; GO:0005634; GO:0006261; GO:0007062; GO:0051301 7472 FUN_043582 626 843 552 615 458 NA NA NA NA NA NA NA 7473 FUN_043583 1631 1157 447 1603 1276 NA NA NA NA NA NA NA 7474 FUN_043584 1396 567 203 916 966 NA NA NA NA NA NA NA 7475 FUN_043585 6762 6129 3566 7094 3153 NA NA NA NA NA NA NA 7476 FUN_043586 3038 1836 2238 3931 990 NA NA NA NA NA NA NA 7477 FUN_043587 588 439 327 633 360 NA NA NA NA NA NA NA 7478 FUN_043588 203 217 98 26 53 NA NA NA NA NA NA NA 7479 FUN_043589 0 0 0 0 8 NA NA NA NA NA NA NA 7480 FUN_044269 3 0 3 6 12 NA NA NA NA NA NA NA 7481 FUN_030339 6 1 10 1 25 ptg000023l:10640942-10641705 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7482 FUN_035129 6379 6316 2752 4194 1407 NA NA NA NA NA NA NA 7483 FUN_035128 160 103 7 115 109 NA NA NA NA NA NA NA 7484 FUN_030331 6 0 8 0 26 ptg000023l:10624732-10625495 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7485 FUN_030333 5 0 6 0 22 ptg000023l:10628784-10629547 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7486 FUN_030335 6 0 7 0 23 ptg000023l:10632837-10633600 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7487 FUN_035122 667 362 503 728 449 NA NA NA NA NA NA NA 7488 FUN_035121 669 421 380 555 520 NA NA NA NA NA NA NA 7489 FUN_000545 1300 1096 767 1181 607 ntLink_6:4226988-4232043 Q9Y315 5.16e-49 Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) Homo sapiens (Human) carbohydrate catabolic process [GO:0016052]; deoxyribonucleoside catabolic process [GO:0046121]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; pentose-phosphate shunt [GO:0006098] GO:0004139; GO:0005576; GO:0005654; GO:0005829; GO:0006098; GO:0009264; GO:0016052; GO:0034774; GO:0046121; GO:0046386; GO:1904813 7490 FUN_000545 1300 1096 767 1181 607 ntLink_6:4226988-4232043 Q9Y315 1.61e-26 Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) Homo sapiens (Human) carbohydrate catabolic process [GO:0016052]; deoxyribonucleoside catabolic process [GO:0046121]; deoxyribonucleotide catabolic process [GO:0009264]; deoxyribose phosphate catabolic process [GO:0046386]; pentose-phosphate shunt [GO:0006098] GO:0004139; GO:0005576; GO:0005654; GO:0005829; GO:0006098; GO:0009264; GO:0016052; GO:0034774; GO:0046121; GO:0046386; GO:1904813 7491 FUN_036478 797 449 338 874 794 ptg000025l:18578601-18619793 Q4G0P3 1.82e-30 Hydrocephalus-inducing protein homolog Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 7492 FUN_036479 50 51 37 98 119 NA NA NA NA NA NA NA 7493 FUN_000544 367 275 210 350 140 NA NA NA NA NA NA NA 7494 FUN_036474 81 211 133 40 198 NA NA NA NA NA NA NA 7495 FUN_036475 21 841 0 4 6 NA NA NA NA NA NA NA 7496 FUN_036470 29 14 0 0 0 NA NA NA NA NA NA NA 7497 FUN_041513 1279 794 591 1288 942 NA NA NA NA NA NA NA 7498 FUN_036472 189 109 111 159 63 NA NA NA NA NA NA NA 7499 FUN_036473 32 289 341 60 172 NA NA NA NA NA NA NA 7500 FUN_041512 2039 1413 901 1618 1479 NA NA NA NA NA NA NA 7501 FUN_002169 0 0 0 0 11 NA NA NA NA NA NA NA 7502 FUN_035544 1639 1234 1517 923 779 NA NA NA NA NA NA NA 7503 FUN_002165 17 5 6 13 3 NA NA NA NA NA NA NA 7504 FUN_041515 762 628 303 391 296 NA NA NA NA NA NA NA 7505 FUN_002167 9 12 11 0 87 NA NA NA NA NA NA NA 7506 FUN_002166 9 0 0 0 7 NA NA NA NA NA NA NA 7507 FUN_002162 10 0 21 3 112 NA NA NA NA NA NA NA 7508 FUN_000543 0 19 9 25 10 NA NA NA NA NA NA NA 7509 FUN_000542 78 44 121 44 29 ntLink_6:4197269-4198400 Q61473 6.89e-32 Transcription factor SOX-17 Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; angiogenesis [GO:0001525]; cardiac cell fate determination [GO:0060913]; cardiogenic plate morphogenesis [GO:0003142]; cell differentiation [GO:0030154]; cell migration involved in gastrulation [GO:0042074]; cellular response to leukemia inhibitory factor [GO:1990830]; common bile duct development [GO:0061009]; embryonic foregut morphogenesis [GO:0048617]; embryonic heart tube development [GO:0035050]; embryonic heart tube morphogenesis [GO:0003143]; embryonic organ development [GO:0048568]; endocardial cell differentiation [GO:0060956]; endocardium formation [GO:0060214]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; endodermal cell differentiation [GO:0035987]; endodermal cell fate determination [GO:0007493]; endodermal cell fate specification [GO:0001714]; endodermal digestive tract morphogenesis [GO:0061031]; gallbladder development [GO:0061010]; gastrulation [GO:0007369]; gene expression [GO:0010467]; heart development [GO:0007507]; heart looping [GO:0001947]; inner cell mass cellular morphogenesis [GO:0001828]; metanephros development [GO:0001656]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; negative regulation of Wnt signaling pathway [GO:0030178]; negative regulation of Wnt signaling pathway involved in heart development [GO:0003308]; outflow tract morphogenesis [GO:0003151]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endodermal cell differentiation [GO:1903226]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein destabilization [GO:0031648]; protein stabilization [GO:0050821]; regulation of cardiac cell fate specification [GO:2000043]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of stem cell division [GO:2000035]; regulation of stem cell proliferation [GO:0072091]; regulation of transcription by RNA polymerase II [GO:0006357]; rostrocaudal neural tube patterning [GO:0021903]; signal transduction involved in regulation of gene expression [GO:0023019]; spermatogenesis [GO:0007283]; stem cell differentiation [GO:0048863]; stem cell fate specification [GO:0048866]; ureter development [GO:0072189]; vasculogenesis [GO:0001570]; Wnt signaling pathway [GO:0016055] GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0001570; GO:0001656; GO:0001706; GO:0001714; GO:0001828; GO:0001947; GO:0003142; GO:0003143; GO:0003151; GO:0003308; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0007283; GO:0007369; GO:0007492; GO:0007493; GO:0007507; GO:0008013; GO:0009653; GO:0010467; GO:0010628; GO:0016055; GO:0021903; GO:0023019; GO:0030154; GO:0030178; GO:0030308; GO:0031648; GO:0035050; GO:0035987; GO:0042074; GO:0043565; GO:0045595; GO:0045732; GO:0045893; GO:0045944; GO:0045995; GO:0048568; GO:0048617; GO:0048863; GO:0048866; GO:0050821; GO:0060214; GO:0060913; GO:0060956; GO:0061009; GO:0061010; GO:0061031; GO:0061629; GO:0072091; GO:0072189; GO:0090090; GO:1903226; GO:1990830; GO:2000035; GO:2000043; GO:2000738 7510 FUN_042187 0 2 23 21 0 NA NA NA NA NA NA NA 7511 FUN_042185 155 105 0 71 189 NA NA NA NA NA NA NA 7512 FUN_035542 43 9 1 17 0 NA NA NA NA NA NA NA 7513 FUN_042183 30 108 3 15 15 NA NA NA NA NA NA NA 7514 FUN_042181 85 0 40 14 300 NA NA NA NA NA NA NA 7515 FUN_042180 30 0 10 11 117 NA NA NA NA NA NA NA 7516 FUN_011714 124 38 76 102 110 ptg000008l:461556-467744 Q00546 8.59e-58 Tenascin-R (TN-R) (Restrictin) Gallus gallus (Chicken) cell adhesion [GO:0007155]; neuron projection development [GO:0031175]; regulation of cell adhesion [GO:0030155] GO:0005615; GO:0007155; GO:0030155; GO:0031175; GO:0062023; GO:0098966 7517 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 4.32e-70 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7518 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 1.02e-65 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7519 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 1.22e-64 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7520 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 6.52e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7521 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 1.01e-62 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7522 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 1.66e-51 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7523 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 1.28e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7524 FUN_001507 265 177 218 174 123 ntLink_6:13083894-13091770 Q96RW7 3.14e-48 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 7525 FUN_031048 9 10 14 26 5 NA NA NA NA NA NA NA 7526 FUN_036017 49 41 0 63 34 ptg000025l:14534738-14535872 Q9N294 1.85e-34 Beta-1,3-galactosyltransferase 5 (Beta-1,3-GalTase 5) (Beta3Gal-T5) (Beta3GalT5) (b3Gal-T5) (EC 2.4.1.-) (Beta-3-Gx-T5) (UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5) (UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5) Pan paniscus (Pygmy chimpanzee) (Bonobo) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0016758 7527 FUN_040039 4171 2442 1195 2511 1748 NA NA NA NA NA NA NA 7528 FUN_004869 642 130 88 490 393 NA NA NA NA NA NA NA 7529 FUN_004862 252 286 251 142 317 ntLink_8:27927091-27931674 Q9JJQ0 1.4e-75 GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506]; GPI anchor metabolic process [GO:0006505]; mannosylation [GO:0097502] GO:0000026; GO:0000030; GO:0005789; GO:0006505; GO:0006506; GO:0097502 7530 FUN_004860 2411 1927 676 762 1100 ntLink_8:27915110-27920614 Q5U2Q4 2.46e-40 Protein mono-ADP-ribosyltransferase PARP16 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 15) (Poly [ADP-ribose] polymerase 16) (PARP-16) Rattus norvegicus (Rat) cellular response to leukemia inhibitory factor [GO:1990830]; endoplasmic reticulum unfolded protein response [GO:0030968]; IRE1-mediated unfolded protein response [GO:0036498]; negative regulation of cell death [GO:0060548]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005635; GO:0005783; GO:0005789; GO:0016779; GO:0019900; GO:0030968; GO:0036498; GO:0043539; GO:0060548; GO:0070213; GO:0071782; GO:0071902; GO:0140804; GO:0140806; GO:0140807; GO:1990404; GO:1990830 7531 FUN_004861 2242 1679 581 1235 1129 NA NA NA NA NA NA NA 7532 FUN_004866 5531 11099 6430 4485 3006 NA NA NA NA NA NA NA 7533 FUN_004867 299 384 249 87 34 ntLink_8:27968546-28042511 Q05609 4.36e-22 Serine/threonine-protein kinase CTR1 (EC 2.7.11.1) (Protein CONSTITUTIVE TRIPLE RESPONSE1) Arabidopsis thaliana (Mouse-ear cress) ethylene-activated signaling pathway [GO:0009873]; gibberellin biosynthetic process [GO:0009686]; negative regulation of ethylene-activated signaling pathway [GO:0010105]; protein autophosphorylation [GO:0046777]; regulation of post-embryonic root development [GO:2000069]; regulation of stem cell division [GO:2000035]; regulation of timing of transition from vegetative to reproductive phase [GO:0048510]; response to ethylene [GO:0009723]; response to fructose [GO:0009750]; response to hypoxia [GO:0001666]; response to sucrose [GO:0009744]; sugar mediated signaling pathway [GO:0010182] GO:0001666; GO:0004674; GO:0004712; GO:0005524; GO:0005789; GO:0009686; GO:0009723; GO:0009744; GO:0009750; GO:0009873; GO:0010105; GO:0010182; GO:0046777; GO:0048510; GO:0106310; GO:2000035; GO:2000069 7534 FUN_004864 4569 3395 1303 2838 2517 NA NA NA NA NA NA NA 7535 FUN_004865 181 154 104 81 140 NA NA NA NA NA NA NA 7536 FUN_031047 14 2 15 7 8 NA NA NA NA NA NA NA 7537 FUN_015343 0 0 22 10 51 NA NA NA NA NA NA NA 7538 FUN_012830 0 3 25 195 123 NA NA NA NA NA NA NA 7539 FUN_002831 7 0 0 2 36 NA NA NA NA NA NA NA 7540 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 2.62e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7541 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 4.7e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7542 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 1.12e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7543 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 4.44e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7544 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 4.61e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7545 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 5.21e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7546 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 8.9e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7547 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 4.49e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7548 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 8.65e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7549 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 1.05e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7550 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 5.94e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7551 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 8.95e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7552 FUN_002830 0 23 0 0 0 ntLink_8:6704079-6706944 Q96AY4 2.29e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7553 FUN_002836 126 43 57 31 215 NA NA NA NA NA NA NA 7554 FUN_002838 30 0 30 0 104 ntLink_8:6742783-6766371 P08548 1.24e-26 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 7555 FUN_002838 30 0 30 0 104 ntLink_8:6742783-6766371 P08548 1.24e-26 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 7556 FUN_032209 1 0 0 0 18 NA NA NA NA NA NA NA 7557 FUN_032208 0 2 9 34 0 NA NA NA NA NA NA NA 7558 FUN_032207 28 13 19 69 0 NA NA NA NA NA NA NA 7559 FUN_032206 76 106 141 181 65 NA NA NA NA NA NA NA 7560 FUN_032205 1767 1979 739 1163 678 NA NA NA NA NA NA NA 7561 FUN_032204 1006 1133 552 631 651 NA NA NA NA NA NA NA 7562 FUN_032203 1072 1174 569 1324 986 NA NA NA NA NA NA NA 7563 FUN_032202 1356 1152 625 1054 1063 NA NA NA NA NA NA NA 7564 FUN_023380 513 206 113 477 362 ptg000017l:6865085-6887070 Q6V0K7 1.4e-21 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 7565 FUN_032200 1360 999 733 1368 896 NA NA NA NA NA NA NA 7566 FUN_040037 47003 29995 34127 47022 11095 ptg000031l:3350940-3362056 P19615 2.59e-33 Major yolk protein (MYP) (Vitellogenin) Strongylocentrotus purpuratus (Purple sea urchin) iron ion homeostasis [GO:0055072]; iron ion transport [GO:0006826] GO:0005615; GO:0005769; GO:0005886; GO:0006826; GO:0045735; GO:0046872; GO:0055037; GO:0055072 7567 FUN_011332 0 0 0 0 6 NA NA NA NA NA NA NA 7568 FUN_000092 6 0 8 0 20 ntLink_4:106847-107610 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7569 FUN_000090 6 1 10 1 18 ntLink_4:102781-103544 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7570 FUN_000096 5 0 11 2 16 ntLink_4:114979-115742 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7571 FUN_000094 4 1 11 1 22 ntLink_4:110913-111676 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7572 FUN_000098 5 0 12 1 17 ntLink_4:119045-119808 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 7573 FUN_040036 909 858 609 729 364 NA NA NA NA NA NA NA 7574 FUN_008776 193 18 162 142 146 ptg000002l:15449003-15450299 P70031 6.24e-27 Cholecystokinin receptor (CCK-XLR) Xenopus laevis (African clawed frog) NA GO:0004930; GO:0005886 7575 FUN_008777 0 0 0 44 0 NA NA NA NA NA NA NA 7576 FUN_008774 0 7 0 39 44 ptg000002l:15439479-15441047 Q9TUP7 2.74e-25 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Canis lupus familiaris (Dog) (Canis familiaris) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 7577 FUN_008775 37 0 11 0 0 ptg000002l:15442440-15444116 P56719 4e-25 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Rattus norvegicus (Rat) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 7578 FUN_008772 157 0 62 93 99 ptg000002l:15430526-15433341 O62809 1.37e-25 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 7579 FUN_008773 23 6 12 2 70 NA NA NA NA NA NA NA 7580 FUN_008770 57 29 17 24 61 NA NA NA NA NA NA NA 7581 FUN_008771 2161 2278 1762 1893 1856 NA NA NA NA NA NA NA 7582 FUN_008778 213 134 183 343 211 ptg000002l:15457870-15459037 Q9Y5X5 1.3e-21 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 7583 FUN_008779 5 101 0 0 0 NA NA NA NA NA NA NA 7584 FUN_041511 22 16 32 53 31 NA NA NA NA NA NA NA 7585 FUN_014866 0 0 0 27 0 NA NA NA NA NA NA NA 7586 FUN_014865 2005 2200 1163 1914 1963 ptg000009l:3792753-3795996 Q02427 2.1e-21 RNA-binding protein 1 Drosophila melanogaster (Fruit fly) mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of gene expression [GO:0010468]; regulation of mRNA 3'-end processing [GO:0031440]; regulation of transcriptional start site selection at RNA polymerase II promoter [GO:0001178]; RNA splicing [GO:0008380] GO:0000381; GO:0000398; GO:0000791; GO:0001178; GO:0003723; GO:0003729; GO:0005634; GO:0008380; GO:0010468; GO:0016607; GO:0031440; GO:0045292 7587 FUN_000541 107 61 53 100 239 NA NA NA NA NA NA NA 7588 FUN_014862 85 78 130 311 78 ptg000009l:3780003-3783759 Q9NRP7 7.64e-25 Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog) Homo sapiens (Human) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium assembly [GO:0060271]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of smoothened signaling pathway [GO:0045880]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of DNA-binding transcription factor activity [GO:0051090]; smoothened signaling pathway [GO:0007224] GO:0001222; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0007228; GO:0007420; GO:0009791; GO:0035082; GO:0042995; GO:0045880; GO:0046872; GO:0051090; GO:0060271; GO:0106310 7589 FUN_041516 2092 2036 1113 1645 1306 NA NA NA NA NA NA NA 7590 FUN_041519 3098 1656 2269 4430 3390 ptg000035l:4646596-4677404 Q28084 1.06e-42 Collagen alpha-3(IV) chain Bos taurus (Bovine) cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198] GO:0005201; GO:0005581; GO:0005604; GO:0005615; GO:0007155; GO:0030198; GO:0031012 7591 FUN_041518 718 589 356 704 638 NA NA NA NA NA NA NA 7592 FUN_000549 2 0 0 161 12 ntLink_6:4250359-4251022 Q5FVH4 3.01e-25 AKT-interacting protein (Fused toes protein homolog) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; early endosome to late endosome transport [GO:0045022]; endosome organization [GO:0007032]; endosome to lysosome transport [GO:0008333]; lysosome organization [GO:0007040]; positive regulation of protein binding [GO:0032092]; positive regulation of protein phosphorylation [GO:0001934]; protein localization to perinuclear region of cytoplasm [GO:1905719]; protein polyubiquitination [GO:0000209]; protein transport [GO:0015031] GO:0000209; GO:0001934; GO:0005634; GO:0005829; GO:0005886; GO:0006915; GO:0007032; GO:0007040; GO:0008333; GO:0015031; GO:0032092; GO:0045022; GO:0061631; GO:0070695; GO:1905719 7593 FUN_000548 46 43 9 22 34 NA NA NA NA NA NA NA 7594 FUN_014869 225 246 217 274 425 NA NA NA NA NA NA NA 7595 FUN_014868 937 386 338 594 685 NA NA NA NA NA NA NA 7596 FUN_033159 2 7 18 2 0 ptg000023l:40525589-40531098 Q96AY4 8.46e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7597 FUN_033159 2 7 18 2 0 ptg000023l:40525589-40531098 Q96AY4 2.17e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7598 FUN_033159 2 7 18 2 0 ptg000023l:40525589-40531098 Q96AY4 2.66e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7599 FUN_033159 2 7 18 2 0 ptg000023l:40525589-40531098 Q96AY4 3.15e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7600 FUN_033156 0 8 2 12 6 ptg000023l:40495795-40498595 Q96AY4 6.86e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7601 FUN_033156 0 8 2 12 6 ptg000023l:40495795-40498595 Q96AY4 2.84e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7602 FUN_033156 0 8 2 12 6 ptg000023l:40495795-40498595 Q96AY4 4.83e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7603 FUN_033156 0 8 2 12 6 ptg000023l:40495795-40498595 Q96AY4 6.09e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7604 FUN_033156 0 8 2 12 6 ptg000023l:40495795-40498595 Q96AY4 4.4e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7605 FUN_033157 651 344 172 315 538 NA NA NA NA NA NA NA 7606 FUN_016649 357 318 378 337 308 ptg000011l:5861459-5863052 Q8BJQ9 2.15e-127 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1) (Beta4GalNAcT-1) Mus musculus (Mouse) cartilage development [GO:0051216]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; UDP-glucuronate metabolic process [GO:0046398]; UDP-N-acetylgalactosamine metabolic process [GO:0019276] GO:0001958; GO:0005794; GO:0008376; GO:0008955; GO:0015020; GO:0019276; GO:0030198; GO:0030204; GO:0030206; GO:0032580; GO:0046398; GO:0046872; GO:0047237; GO:0047238; GO:0050653; GO:0051216 7607 FUN_016648 1246 983 642 1111 968 NA NA NA NA NA NA NA 7608 FUN_004747 1044 510 298 751 678 NA NA NA NA NA NA NA 7609 FUN_042969 1125 844 700 649 747 NA NA NA NA NA NA NA 7610 FUN_042968 2452 2646 1921 1329 1182 ptg000047l:2546700-2547105 Q8R235 7.58e-25 Transmembrane protein 203 Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; spermatogenesis [GO:0007283] GO:0005783; GO:0005789; GO:0006874; GO:0007283 7611 FUN_042961 1806 1165 867 1523 1222 ptg000047l:2459921-2462455 Q66II5 4.31e-99 Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016836; GO:0050346 7612 FUN_042961 1806 1165 867 1523 1222 ptg000047l:2459921-2462455 Q66II5 2.06e-23 Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016836; GO:0050346 7613 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7614 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7615 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7616 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 1.5e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7617 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 4.4e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7618 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 3e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7619 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 7.09e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7620 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 1.27e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7621 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 6.14e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7622 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 6.14e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7623 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 1.09e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7624 FUN_016640 547 307 209 633 692 ptg000011l:5705188-5741959 Q96AY4 1.45e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7625 FUN_016643 127 129 95 220 238 ptg000011l:5753604-5759417 Q9CUX1 2.69e-24 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 7626 FUN_016642 53 186 60 93 206 NA NA NA NA NA NA NA 7627 FUN_042965 1411 615 775 1479 1424 NA NA NA NA NA NA NA 7628 FUN_042964 97 71 37 86 52 NA NA NA NA NA NA NA 7629 FUN_016647 1131 626 497 995 1088 NA NA NA NA NA NA NA 7630 FUN_016646 2545 1043 1465 2772 1945 ptg000011l:5802920-5812390 Q96483 5.15e-22 Actin-51 (EC 3.6.4.-) Solanum lycopersicum (Tomato) (Lycopersicon esculentum) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 7631 FUN_016641 5 6 4 2 0 NA NA NA NA NA NA NA 7632 FUN_042960 574 90 105 477 532 ptg000047l:2445002-2448629 Q66II5 6.02e-92 Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016836; GO:0050346 7633 FUN_042960 574 90 105 477 532 ptg000047l:2445002-2448629 Q66II5 5.49e-23 Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-L-proline dehydratase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016836; GO:0050346 7634 FUN_042963 17181 12524 7371 15084 12014 ptg000047l:2472213-2482224 Q5TC82 8.46e-84 Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; B cell homeostasis [GO:0001782]; cellular response to interleukin-1 [GO:0071347]; lymph node development [GO:0048535]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of germinal center formation [GO:0002635]; negative regulation of T-helper 17 cell differentiation [GO:2000320]; negative regulation of T-helper cell differentiation [GO:0045623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; P-body assembly [GO:0033962]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; post-transcriptional regulation of gene expression [GO:0010608]; protein polyubiquitination [GO:0000209]; regulation of germinal center formation [GO:0002634]; regulation of miRNA metabolic process [GO:2000628]; regulation of mRNA stability [GO:0043488]; regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900151]; regulation of T cell receptor signaling pathway [GO:0050856]; spleen development [GO:0048536]; T cell homeostasis [GO:0043029]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852]; T follicular helper cell differentiation [GO:0061470]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000288; GO:0000932; GO:0000956; GO:0001782; GO:0002634; GO:0002635; GO:0003723; GO:0003725; GO:0003729; GO:0003730; GO:0004842; GO:0006511; GO:0008270; GO:0010494; GO:0010608; GO:0030889; GO:0033962; GO:0035198; GO:0035613; GO:0042098; GO:0043029; GO:0043488; GO:0045623; GO:0046007; GO:0048535; GO:0048536; GO:0050852; GO:0050856; GO:0061014; GO:0061158; GO:0061470; GO:0061630; GO:0071347; GO:1900151; GO:1901224; GO:1905762; GO:2000320; GO:2000628 7635 FUN_042962 4052 2469 1965 3841 3248 NA NA NA NA NA NA NA 7636 FUN_016645 1390 875 768 1171 1046 NA NA NA NA NA NA NA 7637 FUN_016644 4003 2879 2310 4080 2914 NA NA NA NA NA NA NA 7638 FUN_042966 6 38 2 0 0 NA NA NA NA NA NA NA 7639 FUN_010526 44 0 0 0 25 NA NA NA NA NA NA NA 7640 FUN_010527 104 64 0 0 63 NA NA NA NA NA NA NA 7641 FUN_010524 0 0 0 0 47 NA NA NA NA NA NA NA 7642 FUN_010520 22 28 24 43 29 NA NA NA NA NA NA NA 7643 FUN_018327 55 0 25 27 20 NA NA NA NA NA NA NA 7644 FUN_010528 21 8 0 0 9 NA NA NA NA NA NA NA 7645 FUN_012018 30 0 0 47 96 ptg000008l:4113764-4117074 P48180 2.12e-26 Acetylcholine receptor subunit alpha-type acr-16 Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0042995; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1904315 7646 FUN_012010 351 71 78 56 88 NA NA NA NA NA NA NA 7647 FUN_012011 45 0 39 78 52 NA NA NA NA NA NA NA 7648 FUN_012012 772 1407 691 1455 1136 ptg000008l:4056172-4064843 O95935 3.06e-24 T-box transcription factor TBX18 (T-box protein 18) Homo sapiens (Human) cell fate specification [GO:0001708]; cochlea morphogenesis [GO:0090103]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation [GO:0060829]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of SA node cell action potential [GO:0098907]; regulation of transcription by RNA polymerase II [GO:0006357]; sinoatrial node cell development [GO:0060931]; sinoatrial node cell fate commitment [GO:0060930]; sinoatrial node development [GO:0003163]; smooth muscle cell differentiation [GO:0051145]; somitogenesis [GO:0001756]; ureter development [GO:0072189] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001227; GO:0001708; GO:0001756; GO:0003163; GO:0005634; GO:0005654; GO:0006357; GO:0016331; GO:0042803; GO:0045893; GO:0051145; GO:0060829; GO:0060930; GO:0060931; GO:0072189; GO:0090103; GO:0090571; GO:0098907; GO:1990837 7649 FUN_012013 0 0 0 0 12 NA NA NA NA NA NA NA 7650 FUN_012014 46 17 49 20 21 NA NA NA NA NA NA NA 7651 FUN_012016 32 29 27 135 228 ptg000008l:4087727-4094725 Q9I8C7 1.69e-34 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 7652 FUN_012017 28 9 16 54 58 NA NA NA NA NA NA NA 7653 FUN_022800 30 17 86 131 215 ptg000017l:103302-117046 Q80ZA4 7.27e-44 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86) Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0016020; GO:0032426; GO:0120234 7654 FUN_022800 30 17 86 131 215 ptg000017l:103302-117046 Q80ZA4 7.27e-44 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) (Protein D86) Mus musculus (Mouse) sensory perception of sound [GO:0007605] GO:0007605; GO:0016020; GO:0032426; GO:0120234 7655 FUN_022801 3 0 28 0 54 NA NA NA NA NA NA NA 7656 FUN_010074 98 64 0 132 97 NA NA NA NA NA NA NA 7657 FUN_020912 0 0 0 0 24 NA NA NA NA NA NA NA 7658 FUN_022803 1711 1602 994 1195 1426 NA NA NA NA NA NA NA 7659 FUN_020914 2 0 1 40 6 NA NA NA NA NA NA NA 7660 FUN_020915 6 10 0 0 33 NA NA NA NA NA NA NA 7661 FUN_009483 0 33 12 0 0 NA NA NA NA NA NA NA 7662 FUN_010076 0 0 13 17 23 NA NA NA NA NA NA NA 7663 FUN_022805 5050 1947 2381 3013 1931 NA NA NA NA NA NA NA 7664 FUN_022806 360 243 111 276 124 ptg000017l:160836-162432 A8WGA0 7.15e-93 Cytochrome P450 27C1 (EC 1.14.19.53) (All-trans retinol 3,4-desaturase) Danio rerio (Zebrafish) (Brachydanio rerio) lipid metabolic process [GO:0006629] GO:0001972; GO:0004497; GO:0005506; GO:0005739; GO:0006629; GO:0016020; GO:0020037; GO:0061896; GO:0061897; GO:0061898; GO:1904768 7665 FUN_022807 38 16 30 0 75 NA NA NA NA NA NA NA 7666 FUN_010071 0 0 0 0 10 NA NA NA NA NA NA NA 7667 FUN_013769 0 16 13 0 27 NA NA NA NA NA NA NA 7668 FUN_013768 1 3 2 4 31 NA NA NA NA NA NA NA 7669 FUN_023298 892 910 838 1360 1432 NA NA NA NA NA NA NA 7670 FUN_023299 390 469 128 138 337 NA NA NA NA NA NA NA 7671 FUN_023296 339 198 80 227 82 ptg000017l:6023436-6027839 A0A2B4SJA1 3.81e-90 NA NA NA NA 7672 FUN_023297 548 289 131 246 267 NA NA NA NA NA NA NA 7673 FUN_023294 2545 3152 383 1070 1140 ptg000017l:5996257-5999376 A0A2B4SES9 1.37e-62 NA NA NA NA 7674 FUN_023292 0 10 0 0 0 ptg000017l:5982453-5984241 A0A2B4SJA1 1.84e-87 NA NA NA NA 7675 FUN_023291 0 0 10 8 3 NA NA NA NA NA NA NA 7676 FUN_008562 141 90 102 186 133 NA NA NA NA NA NA NA 7677 FUN_014089 2387 1444 752 1259 2522 NA NA NA NA NA NA NA 7678 FUN_009418 0 11 0 6 0 NA NA NA NA NA NA NA 7679 FUN_040371 41 226 37 137 211 ptg000031l:7560440-7566979 Q5DU56 3.37e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7680 FUN_040371 41 226 37 137 211 ptg000031l:7560440-7566979 Q5DU56 7.34e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7681 FUN_009410 0 0 5 0 41 NA NA NA NA NA NA NA 7682 FUN_009411 24 0 19 152 29 NA NA NA NA NA NA NA 7683 FUN_009413 37 0 87 0 68 ptg000004l:6555187-6560755 B8VIU6 4.8e-29 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 7684 FUN_009414 54 0 39 90 111 NA NA NA NA NA NA NA 7685 FUN_009415 356 0 314 517 891 NA NA NA NA NA NA NA 7686 FUN_012044 1908 1538 1064 1266 1362 ptg000008l:4502565-4504942 Q3T022 6.26e-28 Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p18) Bos taurus (Bovine) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0003714; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0016607; GO:0043065; GO:0045892; GO:0048025; GO:0061574 7687 FUN_026408 1185 727 945 1120 577 NA NA NA NA NA NA NA 7688 FUN_026409 274 14 572 803 351 NA NA NA NA NA NA NA 7689 FUN_023438 1139 1333 490 1045 421 NA NA NA NA NA NA NA 7690 FUN_023439 676 895 438 1008 588 NA NA NA NA NA NA NA 7691 FUN_023432 103 70 23 74 104 NA NA NA NA NA NA NA 7692 FUN_026401 166 115 38 113 254 NA NA NA NA NA NA NA 7693 FUN_026402 224 163 15 71 118 NA NA NA NA NA NA NA 7694 FUN_026403 101 12 8 11 0 NA NA NA NA NA NA NA 7695 FUN_026404 150 0 5 7 24 NA NA NA NA NA NA NA 7696 FUN_023434 504 432 227 593 286 NA NA NA NA NA NA NA 7697 FUN_023435 677 248 338 698 475 NA NA NA NA NA NA NA 7698 FUN_039929 5588 3500 3764 7849 6079 ptg000031l:1792599-1839692 Q63HN8 3e-36 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 7699 FUN_039929 5588 3500 3764 7849 6079 ptg000031l:1792599-1839692 Q63HN8 4.55e-21 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 7700 FUN_039928 1279 424 658 957 310 NA NA NA NA NA NA NA 7701 FUN_039923 75556 53558 24689 41060 18055 NA NA NA NA NA NA NA 7702 FUN_039922 182 181 106 89 27 NA NA NA NA NA NA NA 7703 FUN_039921 1584 1775 892 2063 1071 NA NA NA NA NA NA NA 7704 FUN_039927 158 120 667 405 53 NA NA NA NA NA NA NA 7705 FUN_039926 59 15 38 29 14 NA NA NA NA NA NA NA 7706 FUN_039925 128 101 127 191 231 NA NA NA NA NA NA NA 7707 FUN_039924 4023 4041 1677 3140 2232 ptg000031l:1757732-1765194 P58389 5.11e-25 Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (PP2A, subunit B', PR53 isoform) (Phosphotyrosyl phosphatase activator) (PTPA) (Serine/threonine-protein phosphatase 2A regulatory subunit 4) (Serine/threonine-protein phosphatase 2A regulatory subunit B') Mus musculus (Mouse) mitotic spindle organization [GO:0007052]; negative regulation of phosphoprotein phosphatase activity [GO:0032515]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of apoptotic process [GO:0043065]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of phosphoprotein phosphatase activity [GO:0043666] GO:0000159; GO:0003755; GO:0004721; GO:0005102; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0007052; GO:0008160; GO:0019888; GO:0032515; GO:0032516; GO:0034704; GO:0035307; GO:0035308; GO:0042803; GO:0043065; GO:0043666; GO:0051721; GO:1904949 7708 FUN_022529 1004 1000 695 1276 449 ptg000016l:10144472-10164621 Q00808 1.27e-26 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 7709 FUN_022529 1004 1000 695 1276 449 ptg000016l:10144472-10164621 Q00808 1.5e-25 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 7710 FUN_022529 1004 1000 695 1276 449 ptg000016l:10144472-10164621 Q00808 6.64e-24 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 7711 FUN_022529 1004 1000 695 1276 449 ptg000016l:10144472-10164621 Q00808 1.74e-23 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 7712 FUN_022529 1004 1000 695 1276 449 ptg000016l:10144472-10164621 Q00808 2.63e-21 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 7713 FUN_022529 1004 1000 695 1276 449 ptg000016l:10144472-10164621 Q00808 7.78e-21 Vegetative incompatibility protein HET-E-1 Podospora anserina (Pleurage anserina) NA GO:0005525 7714 FUN_022528 990 1765 511 383 91 NA NA NA NA NA NA NA 7715 FUN_015685 12 21 0 126 24 NA NA NA NA NA NA NA 7716 FUN_022523 0 4 2 43 7 NA NA NA NA NA NA NA 7717 FUN_022522 6 17 2 7 9 NA NA NA NA NA NA NA 7718 FUN_022521 63 34 148 82 51 NA NA NA NA NA NA NA 7719 FUN_017269 119 8 72 2 79 NA NA NA NA NA NA NA 7720 FUN_037542 0 0 13 0 49 NA NA NA NA NA NA NA 7721 FUN_015356 50 123 93 48 28 ptg000009l:9161634-9168045 Q8K2A6 5.53e-34 Lipase member M (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 3) Mus musculus (Mouse) lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016788 7722 FUN_015357 0 0 50 0 198 NA NA NA NA NA NA NA 7723 FUN_018559 14 0 0 0 4 NA NA NA NA NA NA NA 7724 FUN_018558 14 0 0 0 3 NA NA NA NA NA NA NA 7725 FUN_015353 25 0 0 5 0 NA NA NA NA NA NA NA 7726 FUN_015350 545 408 129 288 308 NA NA NA NA NA NA NA 7727 FUN_015351 0 0 3 0 6 ptg000009l:9106962-9112379 Q4R4S5 1.81e-31 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 7728 FUN_018553 11796 4295 4831 11202 7877 NA NA NA NA NA NA NA 7729 FUN_018552 6235 3212 3343 7892 7256 ptg000012l:10739569-10831517 P21328 2.13e-38 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 7730 FUN_018552 6235 3212 3343 7892 7256 ptg000012l:10739569-10831517 P21328 5.04e-32 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 7731 FUN_018551 96 506 42 243 191 ptg000012l:10735470-10736373 F8J3H2 8.8e-23 NA NA NA NA 7732 FUN_018550 153 131 52 45 44 NA NA NA NA NA NA NA 7733 FUN_018557 11 0 0 0 3 NA NA NA NA NA NA NA 7734 FUN_015358 28 0 25 0 93 NA NA NA NA NA NA NA 7735 FUN_015359 214 53 34 122 31 NA NA NA NA NA NA NA 7736 FUN_040231 123 34 29 73 33 NA NA NA NA NA NA NA 7737 FUN_025171 0 0 0 3 87 NA NA NA NA NA NA NA 7738 FUN_025175 5 0 3 1 20 NA NA NA NA NA NA NA 7739 FUN_025177 8 0 1 0 0 NA NA NA NA NA NA NA 7740 FUN_025176 9 0 0 0 10 NA NA NA NA NA NA NA 7741 FUN_004667 336 266 80 24 26 NA NA NA NA NA NA NA 7742 FUN_017859 2941 1321 1375 2822 2474 NA NA NA NA NA NA NA 7743 FUN_017858 879 349 305 423 330 NA NA NA NA NA NA NA 7744 FUN_017855 0 57 39 87 19 ptg000012l:1131647-1134995 A0A1S4F2V5 2.12e-33 NA NA NA NA 7745 FUN_017855 0 57 39 87 19 ptg000012l:1131647-1134995 A0A1S4F2V5 2.33e-21 NA NA NA NA 7746 FUN_018886 0 6 0 0 40 NA NA NA NA NA NA NA 7747 FUN_017852 9787 15328 6725 10107 5613 ptg000012l:1116304-1116922 O73817 4.32e-125 Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005634; GO:0005737; GO:0005839; GO:0019774; GO:0043161 7748 FUN_017850 690 398 442 546 557 NA NA NA NA NA NA NA 7749 FUN_024802 42 75 5 285 106 NA NA NA NA NA NA NA 7750 FUN_024803 7 8 47 13 13 NA NA NA NA NA NA NA 7751 FUN_024800 126 34 7 44 106 ptg000018l:11204589-11205111 Q6NUT3 6.84e-36 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 7752 FUN_024801 364 497 384 503 536 NA NA NA NA NA NA NA 7753 FUN_024806 0 0 0 0 6 NA NA NA NA NA NA NA 7754 FUN_024807 0 0 0 4 30 NA NA NA NA NA NA NA 7755 FUN_024804 1000 974 687 1213 1202 NA NA NA NA NA NA NA 7756 FUN_024808 5 5 0 37 37 NA NA NA NA NA NA NA 7757 FUN_024809 0 4 15 0 0 NA NA NA NA NA NA NA 7758 FUN_004660 299 520 308 870 189 NA NA NA NA NA NA NA 7759 FUN_038322 135 62 53 159 153 NA NA NA NA NA NA NA 7760 FUN_038323 35 0 27 34 16 NA NA NA NA NA NA NA 7761 FUN_038320 347 38 194 420 425 NA NA NA NA NA NA NA 7762 FUN_038321 358 207 221 453 526 NA NA NA NA NA NA NA 7763 FUN_038326 345 206 211 389 486 NA NA NA NA NA NA NA 7764 FUN_038327 135 53 59 157 155 NA NA NA NA NA NA NA 7765 FUN_018441 774 605 201 633 360 ptg000012l:9379589-9385301 P20664 4.03e-24 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 7766 FUN_011557 59 30 65 26 257 NA NA NA NA NA NA NA 7767 FUN_038328 23 0 21 37 15 NA NA NA NA NA NA NA 7768 FUN_031800 365 406 223 305 233 NA NA NA NA NA NA NA 7769 FUN_031801 7539 7898 4578 6136 4704 ptg000023l:25612097-25623788 Q6P026 6.2e-40 Barrier-to-autointegration factor Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; chromosome condensation [GO:0030261]; chromosome segregation [GO:0007059]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of protein ADP-ribosylation [GO:0010836]; negative regulation of type I interferon production [GO:0032480]; response to oxidative stress [GO:0006979] GO:0000785; GO:0003677; GO:0005635; GO:0005654; GO:0005737; GO:0006325; GO:0006979; GO:0007059; GO:0007084; GO:0010836; GO:0030261; GO:0032480 7770 FUN_031802 2649 2263 2395 3420 1917 NA NA NA NA NA NA NA 7771 FUN_031809 268 115 594 262 277 NA NA NA NA NA NA NA 7772 FUN_018440 601 375 144 275 393 NA NA NA NA NA NA NA 7773 FUN_019688 18 57 0 4 466 NA NA NA NA NA NA NA 7774 FUN_019689 0 27 0 0 0 NA NA NA NA NA NA NA 7775 FUN_019682 2 5 6 2 9 NA NA NA NA NA NA NA 7776 FUN_019686 0 0 6 0 0 NA NA NA NA NA NA NA 7777 FUN_019687 168 110 76 0 1103 NA NA NA NA NA NA NA 7778 FUN_024538 321 1 2 37 2 NA NA NA NA NA NA NA 7779 FUN_024539 761 162 322 1001 377 NA NA NA NA NA NA NA 7780 FUN_012015 61 0 40 100 79 NA NA NA NA NA NA NA 7781 FUN_008127 29 7 38 0 263 NA NA NA NA NA NA NA 7782 FUN_001155 1601 956 1213 1367 718 ntLink_6:9192394-9194444 Q16611 1.59e-29 Bcl-2 homologous antagonist/killer (Apoptosis regulator BAK) (Bcl-2-like protein 7) (Bcl2-L-7) Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; animal organ regeneration [GO:0031100]; apoptotic process [GO:0006915]; apoptotic process involved in blood vessel morphogenesis [GO:1902262]; apoptotic signaling pathway [GO:0097190]; B cell apoptotic process [GO:0001783]; B cell homeostasis [GO:0001782]; B cell negative selection [GO:0002352]; blood vessel remodeling [GO:0001974]; brain development [GO:0007420]; calcium ion transport into cytosol [GO:0060402]; cellular response to mechanical stimulus [GO:0071260]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; endocrine pancreas development [GO:0031018]; endoplasmic reticulum calcium ion homeostasis [GO:0032469]; epithelial cell proliferation [GO:0050673]; establishment or maintenance of transmembrane electrochemical gradient [GO:0010248]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; fibroblast apoptotic process [GO:0044346]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; limb morphogenesis [GO:0035108]; mitochondrial fusion [GO:0008053]; myeloid cell homeostasis [GO:0002262]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of endoplasmic reticulum calcium ion concentration [GO:0032471]; negative regulation of gene expression [GO:0010629]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of endoplasmic reticulum unfolded protein response [GO:1900103]; positive regulation of IRE1-mediated unfolded protein response [GO:1903896]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of proteolysis [GO:0045862]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; post-embryonic camera-type eye morphogenesis [GO:0048597]; regulation of cell cycle [GO:0051726]; regulation of mitochondrial membrane permeability [GO:0046902]; regulation of mitochondrial membrane potential [GO:0051881]; release of cytochrome c from mitochondria [GO:0001836]; response to ethanol [GO:0045471]; response to fungus [GO:0009620]; response to gamma radiation [GO:0010332]; response to hydrogen peroxide [GO:0042542]; response to mycotoxin [GO:0010046]; response to organic cyclic compound [GO:0014070]; response to UV-C [GO:0010225]; response to xenobiotic stimulus [GO:0009410]; thymocyte apoptotic process [GO:0070242]; vagina development [GO:0060068] GO:0001782; GO:0001783; GO:0001836; GO:0001974; GO:0002262; GO:0002352; GO:0005739; GO:0005741; GO:0005783; GO:0005829; GO:0006915; GO:0007420; GO:0007568; GO:0008053; GO:0008285; GO:0008630; GO:0008635; GO:0009410; GO:0009620; GO:0010046; GO:0010225; GO:0010248; GO:0010332; GO:0010524; GO:0010629; GO:0014070; GO:0018105; GO:0031018; GO:0031072; GO:0031100; GO:0031334; GO:0032469; GO:0032471; GO:0033137; GO:0034620; GO:0034644; GO:0035108; GO:0042542; GO:0042802; GO:0042803; GO:0043065; GO:0044325; GO:0044346; GO:0044877; GO:0045471; GO:0045862; GO:0046872; GO:0046902; GO:0046930; GO:0046982; GO:0048597; GO:0050673; GO:0051087; GO:0051400; GO:0051726; GO:0051881; GO:0060068; GO:0060402; GO:0070059; GO:0070242; GO:0071260; GO:0090200; GO:0090201; GO:0097136; GO:0097145; GO:0097190; GO:0097192; GO:0097202; GO:1900103; GO:1901029; GO:1901030; GO:1902262; GO:1903896 7783 FUN_008124 2305 1672 979 2660 1721 ptg000002l:8279991-8301566 Q8BQZ4 4.77e-90 Ral GTPase-activating protein subunit beta (p170) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; Ral protein signal transduction [GO:0032484]; regulation of exocyst localization [GO:0060178]; regulation of protein localization [GO:0032880]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005829; GO:0032484; GO:0032880; GO:0046982; GO:0051056; GO:0060178; GO:0090630 7784 FUN_008122 4043 1983 1812 3540 2713 NA NA NA NA NA NA NA 7785 FUN_044268 2 2 16 5 66 NA NA NA NA NA NA NA 7786 FUN_035328 4609 1604 2308 2358 2188 NA NA NA NA NA NA NA 7787 FUN_044265 4 8 32 24 152 NA NA NA NA NA NA NA 7788 FUN_044267 5 2 7 7 6 NA NA NA NA NA NA NA 7789 FUN_035321 150 85 85 118 116 NA NA NA NA NA NA NA 7790 FUN_044261 0 1 1 2 7 NA NA NA NA NA NA NA 7791 FUN_035323 2814 1873 1417 1767 1406 NA NA NA NA NA NA NA 7792 FUN_044263 1 0 4 3 10 NA NA NA NA NA NA NA 7793 FUN_036672 0 0 1 0 34 NA NA NA NA NA NA NA 7794 FUN_001949 3 81 3 16 21 NA NA NA NA NA NA NA 7795 FUN_001946 37 90 18 154 129 NA NA NA NA NA NA NA 7796 FUN_001947 4085 2698 2227 7392 3283 ntLink_6:18142433-18167049 P40818 9.68e-21 Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to nerve growth factor stimulus [GO:1990090]; endosome organization [GO:0007032]; mitotic cytokinesis [GO:0000281]; negative regulation of lysosomal protein catabolic process [GO:1905166]; positive regulation of amyloid fibril formation [GO:1905908]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; Ras protein signal transduction [GO:0007265]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of protein localization [GO:0032880]; regulation of protein stability [GO:0031647]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000281; GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0006511; GO:0007032; GO:0007265; GO:0014069; GO:0016579; GO:0017124; GO:0019897; GO:0030496; GO:0031313; GO:0031647; GO:0032880; GO:0043197; GO:0045296; GO:0070536; GO:0071108; GO:0071549; GO:0090263; GO:0098978; GO:0099576; GO:1905166; GO:1905908; GO:1990090 7797 FUN_036678 19 69 47 41 16 NA NA NA NA NA NA NA 7798 FUN_001945 92 49 38 116 48 NA NA NA NA NA NA NA 7799 FUN_001942 10 0 4 0 26 NA NA NA NA NA NA NA 7800 FUN_001943 1884 803 963 1425 924 NA NA NA NA NA NA NA 7801 FUN_001940 18927 11597 6753 13357 6117 ntLink_6:18050778-18056608 Q87PP5 1.19e-79 Glycine betaine/proline/choline/ectoine transporter VP1456 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0022857 7802 FUN_001941 1969 1216 1025 1936 1848 NA NA NA NA NA NA NA 7803 FUN_039492 0 22 0 18 0 NA NA NA NA NA NA NA 7804 FUN_039491 0 0 8 0 0 NA NA NA NA NA NA NA 7805 FUN_039495 620 128 140 172 345 NA NA NA NA NA NA NA 7806 FUN_039499 10 0 21 0 81 NA NA NA NA NA NA NA 7807 FUN_035497 553 304 293 732 604 NA NA NA NA NA NA NA 7808 FUN_035494 2361 1442 780 1619 1330 NA NA NA NA NA NA NA 7809 FUN_035492 27 0 0 0 0 NA NA NA NA NA NA NA 7810 FUN_035491 6 51 16 30 15 NA NA NA NA NA NA NA 7811 FUN_035490 1404 1254 820 926 349 NA NA NA NA NA NA NA 7812 FUN_035499 399 175 178 346 176 NA NA NA NA NA NA NA 7813 FUN_035498 513 423 246 532 398 NA NA NA NA NA NA NA 7814 FUN_031376 0 0 2 20 2 NA NA NA NA NA NA NA 7815 FUN_031377 79 69 0 100 14 NA NA NA NA NA NA NA 7816 FUN_031374 256 42 90 182 151 NA NA NA NA NA NA NA 7817 FUN_031375 0 61 0 0 44 NA NA NA NA NA NA NA 7818 FUN_031373 0 36 36 5 40 ptg000023l:20215044-20234725 Q7RTR2 2.35e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7819 FUN_031373 0 36 36 5 40 ptg000023l:20215044-20234725 Q7RTR2 4.53e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7820 FUN_031373 0 36 36 5 40 ptg000023l:20215044-20234725 Q7RTR2 1.48e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7821 FUN_031373 0 36 36 5 40 ptg000023l:20215044-20234725 Q7RTR2 6.29e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 7822 FUN_031378 0 0 0 0 45 NA NA NA NA NA NA NA 7823 FUN_039145 8 0 12 10 54 NA NA NA NA NA NA NA 7824 FUN_026325 129 30 11 0 29 NA NA NA NA NA NA NA 7825 FUN_039147 12 0 0 0 26 NA NA NA NA NA NA NA 7826 FUN_039142 4 2 7 10 34 NA NA NA NA NA NA NA 7827 FUN_039149 8 0 0 0 0 NA NA NA NA NA NA NA 7828 FUN_028783 36 24 15 49 34 ptg000022l:3968378-3976702 Q96AY4 3.62e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7829 FUN_028783 36 24 15 49 34 ptg000022l:3968378-3976702 Q96AY4 3.31e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7830 FUN_028783 36 24 15 49 34 ptg000022l:3968378-3976702 Q96AY4 9.92e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7831 FUN_028783 36 24 15 49 34 ptg000022l:3968378-3976702 Q96AY4 3.49e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7832 FUN_028783 36 24 15 49 34 ptg000022l:3968378-3976702 Q96AY4 1.24e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7833 FUN_028783 36 24 15 49 34 ptg000022l:3968378-3976702 Q96AY4 8.4e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 7834 FUN_027722 40 45 0 55 28 NA NA NA NA NA NA NA 7835 FUN_027723 4 9 0 0 0 NA NA NA NA NA NA NA 7836 FUN_026321 85 5 5 0 2 NA NA NA NA NA NA NA 7837 FUN_013354 4011 2727 2725 4457 3808 ptg000008l:21593868-21642343 P42346 8.62e-32 Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; behavioral response to pain [GO:0048266]; brain development [GO:0007420]; calcineurin-NFAT signaling cascade [GO:0033173]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell projection organization [GO:0030030]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to nutrient levels [GO:0031669]; cellular response to starvation [GO:0009267]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; inflammatory response [GO:0006954]; long-term memory [GO:0007616]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; neuronal action potential [GO:0019228]; nucleus localization [GO:0051647]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of translation [GO:0045727]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of autophagy [GO:0010506]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of carbohydrate utilization [GO:0043610]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; regulation of circadian rhythm [GO:0042752]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of locomotor rhythm [GO:1904059]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; regulation of translation at synapse, modulating synaptic transmission [GO:0099547]; response to activity [GO:0014823]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; rhythmic process [GO:0048511]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T-helper 1 cell lineage commitment [GO:0002296]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] GO:0000139; GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001932; GO:0001933; GO:0001934; GO:0001938; GO:0002296; GO:0003007; GO:0003179; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005635; GO:0005737; GO:0005741; GO:0005764; GO:0005765; GO:0005789; GO:0005829; GO:0005979; GO:0006109; GO:0006112; GO:0006207; GO:0006468; GO:0006954; GO:0007040; GO:0007281; GO:0007420; GO:0007584; GO:0007616; GO:0008361; GO:0008542; GO:0009267; GO:0009408; GO:0009791; GO:0010506; GO:0010507; GO:0010592; GO:0010628; GO:0010718; GO:0010831; GO:0010942; GO:0010976; GO:0012505; GO:0014042; GO:0014736; GO:0014823; GO:0016020; GO:0016236; GO:0016242; GO:0016301; GO:0016310; GO:0016605; GO:0018105; GO:0018107; GO:0019228; GO:0019901; GO:0019904; GO:0021510; GO:0030030; GO:0030425; GO:0030838; GO:0031397; GO:0031529; GO:0031641; GO:0031667; GO:0031669; GO:0031929; GO:0031931; GO:0031932; GO:0031998; GO:0032095; GO:0032868; GO:0032956; GO:0032991; GO:0033173; GO:0034198; GO:0035176; GO:0035264; GO:0038202; GO:0042060; GO:0042220; GO:0042752; GO:0042802; GO:0043022; GO:0043087; GO:0043200; GO:0043278; GO:0043610; GO:0045182; GO:0045335; GO:0045429; GO:0045670; GO:0045727; GO:0045792; GO:0045859; GO:0045945; GO:0046777; GO:0046889; GO:0048255; GO:0048266; GO:0048511; GO:0048661; GO:0048709; GO:0048714; GO:0048738; GO:0050731; GO:0050769; GO:0050882; GO:0051219; GO:0051496; GO:0051549; GO:0051647; GO:0051896; GO:0051897; GO:0055006; GO:0055013; GO:0060048; GO:0060135; GO:0060252; GO:0060999; GO:0061051; GO:0070885; GO:0071230; GO:0071233; GO:0071456; GO:0090335; GO:0090559; GO:0098978; GO:0099524; GO:0099547; GO:0106310; GO:1901216; GO:1901838; GO:1903691; GO:1904000; GO:1904056; GO:1904058; GO:1904059; GO:1904193; GO:1904197; GO:1904206; GO:1904213; GO:1990253; GO:2000774 7838 FUN_013354 4011 2727 2725 4457 3808 ptg000008l:21593868-21642343 P42346 1.14e-29 Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; behavioral response to pain [GO:0048266]; brain development [GO:0007420]; calcineurin-NFAT signaling cascade [GO:0033173]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell projection organization [GO:0030030]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to nutrient levels [GO:0031669]; cellular response to starvation [GO:0009267]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; inflammatory response [GO:0006954]; long-term memory [GO:0007616]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; neuronal action potential [GO:0019228]; nucleus localization [GO:0051647]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of translation [GO:0045727]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of autophagy [GO:0010506]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of carbohydrate utilization [GO:0043610]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; regulation of circadian rhythm [GO:0042752]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of locomotor rhythm [GO:1904059]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; regulation of translation at synapse, modulating synaptic transmission [GO:0099547]; response to activity [GO:0014823]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; rhythmic process [GO:0048511]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T-helper 1 cell lineage commitment [GO:0002296]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] GO:0000139; GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001932; GO:0001933; GO:0001934; GO:0001938; GO:0002296; GO:0003007; GO:0003179; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005635; GO:0005737; GO:0005741; GO:0005764; GO:0005765; GO:0005789; GO:0005829; GO:0005979; GO:0006109; GO:0006112; GO:0006207; GO:0006468; GO:0006954; GO:0007040; GO:0007281; GO:0007420; GO:0007584; GO:0007616; GO:0008361; GO:0008542; GO:0009267; GO:0009408; GO:0009791; GO:0010506; GO:0010507; GO:0010592; GO:0010628; GO:0010718; GO:0010831; GO:0010942; GO:0010976; GO:0012505; GO:0014042; GO:0014736; GO:0014823; GO:0016020; GO:0016236; GO:0016242; GO:0016301; GO:0016310; GO:0016605; GO:0018105; GO:0018107; GO:0019228; GO:0019901; GO:0019904; GO:0021510; GO:0030030; GO:0030425; GO:0030838; GO:0031397; GO:0031529; GO:0031641; GO:0031667; GO:0031669; GO:0031929; GO:0031931; GO:0031932; GO:0031998; GO:0032095; GO:0032868; GO:0032956; GO:0032991; GO:0033173; GO:0034198; GO:0035176; GO:0035264; GO:0038202; GO:0042060; GO:0042220; GO:0042752; GO:0042802; GO:0043022; GO:0043087; GO:0043200; GO:0043278; GO:0043610; GO:0045182; GO:0045335; GO:0045429; GO:0045670; GO:0045727; GO:0045792; GO:0045859; GO:0045945; GO:0046777; GO:0046889; GO:0048255; GO:0048266; GO:0048511; GO:0048661; GO:0048709; GO:0048714; GO:0048738; GO:0050731; GO:0050769; GO:0050882; GO:0051219; GO:0051496; GO:0051549; GO:0051647; GO:0051896; GO:0051897; GO:0055006; GO:0055013; GO:0060048; GO:0060135; GO:0060252; GO:0060999; GO:0061051; GO:0070885; GO:0071230; GO:0071233; GO:0071456; GO:0090335; GO:0090559; GO:0098978; GO:0099524; GO:0099547; GO:0106310; GO:1901216; GO:1901838; GO:1903691; GO:1904000; GO:1904056; GO:1904058; GO:1904059; GO:1904193; GO:1904197; GO:1904206; GO:1904213; GO:1990253; GO:2000774 7839 FUN_013354 4011 2727 2725 4457 3808 ptg000008l:21593868-21642343 P42346 3.7e-26 Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; behavioral response to pain [GO:0048266]; brain development [GO:0007420]; calcineurin-NFAT signaling cascade [GO:0033173]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell projection organization [GO:0030030]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to nutrient levels [GO:0031669]; cellular response to starvation [GO:0009267]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; inflammatory response [GO:0006954]; long-term memory [GO:0007616]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; neuronal action potential [GO:0019228]; nucleus localization [GO:0051647]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of translation [GO:0045727]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of autophagy [GO:0010506]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of carbohydrate utilization [GO:0043610]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; regulation of circadian rhythm [GO:0042752]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of locomotor rhythm [GO:1904059]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; regulation of translation at synapse, modulating synaptic transmission [GO:0099547]; response to activity [GO:0014823]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; rhythmic process [GO:0048511]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T-helper 1 cell lineage commitment [GO:0002296]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] GO:0000139; GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001932; GO:0001933; GO:0001934; GO:0001938; GO:0002296; GO:0003007; GO:0003179; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005635; GO:0005737; GO:0005741; GO:0005764; GO:0005765; GO:0005789; GO:0005829; GO:0005979; GO:0006109; GO:0006112; GO:0006207; GO:0006468; GO:0006954; GO:0007040; GO:0007281; GO:0007420; GO:0007584; GO:0007616; GO:0008361; GO:0008542; GO:0009267; GO:0009408; GO:0009791; GO:0010506; GO:0010507; GO:0010592; GO:0010628; GO:0010718; GO:0010831; GO:0010942; GO:0010976; GO:0012505; GO:0014042; GO:0014736; GO:0014823; GO:0016020; GO:0016236; GO:0016242; GO:0016301; GO:0016310; GO:0016605; GO:0018105; GO:0018107; GO:0019228; GO:0019901; GO:0019904; GO:0021510; GO:0030030; GO:0030425; GO:0030838; GO:0031397; GO:0031529; GO:0031641; GO:0031667; GO:0031669; GO:0031929; GO:0031931; GO:0031932; GO:0031998; GO:0032095; GO:0032868; GO:0032956; GO:0032991; GO:0033173; GO:0034198; GO:0035176; GO:0035264; GO:0038202; GO:0042060; GO:0042220; GO:0042752; GO:0042802; GO:0043022; GO:0043087; GO:0043200; GO:0043278; GO:0043610; GO:0045182; GO:0045335; GO:0045429; GO:0045670; GO:0045727; GO:0045792; GO:0045859; GO:0045945; GO:0046777; GO:0046889; GO:0048255; GO:0048266; GO:0048511; GO:0048661; GO:0048709; GO:0048714; GO:0048738; GO:0050731; GO:0050769; GO:0050882; GO:0051219; GO:0051496; GO:0051549; GO:0051647; GO:0051896; GO:0051897; GO:0055006; GO:0055013; GO:0060048; GO:0060135; GO:0060252; GO:0060999; GO:0061051; GO:0070885; GO:0071230; GO:0071233; GO:0071456; GO:0090335; GO:0090559; GO:0098978; GO:0099524; GO:0099547; GO:0106310; GO:1901216; GO:1901838; GO:1903691; GO:1904000; GO:1904056; GO:1904058; GO:1904059; GO:1904193; GO:1904197; GO:1904206; GO:1904213; GO:1990253; GO:2000774 7840 FUN_013354 4011 2727 2725 4457 3808 ptg000008l:21593868-21642343 P42346 2.96e-22 Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; behavioral response to pain [GO:0048266]; brain development [GO:0007420]; calcineurin-NFAT signaling cascade [GO:0033173]; cardiac cell development [GO:0055006]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle tissue development [GO:0048738]; cell projection organization [GO:0030030]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to leucine starvation [GO:1990253]; cellular response to nutrient levels [GO:0031669]; cellular response to starvation [GO:0009267]; energy reserve metabolic process [GO:0006112]; germ cell development [GO:0007281]; heart morphogenesis [GO:0003007]; heart valve morphogenesis [GO:0003179]; inflammatory response [GO:0006954]; long-term memory [GO:0007616]; lysosome organization [GO:0007040]; macroautophagy [GO:0016236]; maternal process involved in female pregnancy [GO:0060135]; mRNA stabilization [GO:0048255]; multicellular organism growth [GO:0035264]; negative regulation of autophagy [GO:0010507]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of cell size [GO:0045792]; negative regulation of cholangiocyte apoptotic process [GO:1904193]; negative regulation of iodide transmembrane transport [GO:1904213]; negative regulation of macroautophagy [GO:0016242]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; neuronal action potential [GO:0019228]; nucleus localization [GO:0051647]; oligodendrocyte differentiation [GO:0048709]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell death [GO:0010942]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; positive regulation of cellular senescence [GO:2000774]; positive regulation of cholangiocyte proliferation [GO:1904056]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of eating behavior [GO:1904000]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of granulosa cell proliferation [GO:1904197]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of myotube differentiation [GO:0010831]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of skeletal muscle hypertrophy [GO:1904206]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of transcription by RNA polymerase III [GO:0045945]; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901838]; positive regulation of translation [GO:0045727]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of autophagy [GO:0010506]; regulation of brown fat cell differentiation [GO:0090335]; regulation of carbohydrate metabolic process [GO:0006109]; regulation of carbohydrate utilization [GO:0043610]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; regulation of circadian rhythm [GO:0042752]; regulation of fatty acid beta-oxidation [GO:0031998]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of GTPase activity [GO:0043087]; regulation of locomotor rhythm [GO:1904059]; regulation of membrane permeability [GO:0090559]; regulation of myelination [GO:0031641]; regulation of osteoclast differentiation [GO:0045670]; regulation of protein kinase activity [GO:0045859]; regulation of protein kinase B signaling [GO:0051896]; regulation of protein phosphorylation [GO:0001932]; regulation of response to food [GO:0032095]; regulation of translation at synapse, modulating synaptic transmission [GO:0099547]; response to activity [GO:0014823]; response to amino acid [GO:0043200]; response to cocaine [GO:0042220]; response to heat [GO:0009408]; response to insulin [GO:0032868]; response to morphine [GO:0043278]; response to nutrient [GO:0007584]; response to nutrient levels [GO:0031667]; rhythmic process [GO:0048511]; ruffle organization [GO:0031529]; social behavior [GO:0035176]; spinal cord development [GO:0021510]; T-helper 1 cell lineage commitment [GO:0002296]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202]; visual learning [GO:0008542]; voluntary musculoskeletal movement [GO:0050882]; wound healing [GO:0042060] GO:0000139; GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001932; GO:0001933; GO:0001934; GO:0001938; GO:0002296; GO:0003007; GO:0003179; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005635; GO:0005737; GO:0005741; GO:0005764; GO:0005765; GO:0005789; GO:0005829; GO:0005979; GO:0006109; GO:0006112; GO:0006207; GO:0006468; GO:0006954; GO:0007040; GO:0007281; GO:0007420; GO:0007584; GO:0007616; GO:0008361; GO:0008542; GO:0009267; GO:0009408; GO:0009791; GO:0010506; GO:0010507; GO:0010592; GO:0010628; GO:0010718; GO:0010831; GO:0010942; GO:0010976; GO:0012505; GO:0014042; GO:0014736; GO:0014823; GO:0016020; GO:0016236; GO:0016242; GO:0016301; GO:0016310; GO:0016605; GO:0018105; GO:0018107; GO:0019228; GO:0019901; GO:0019904; GO:0021510; GO:0030030; GO:0030425; GO:0030838; GO:0031397; GO:0031529; GO:0031641; GO:0031667; GO:0031669; GO:0031929; GO:0031931; GO:0031932; GO:0031998; GO:0032095; GO:0032868; GO:0032956; GO:0032991; GO:0033173; GO:0034198; GO:0035176; GO:0035264; GO:0038202; GO:0042060; GO:0042220; GO:0042752; GO:0042802; GO:0043022; GO:0043087; GO:0043200; GO:0043278; GO:0043610; GO:0045182; GO:0045335; GO:0045429; GO:0045670; GO:0045727; GO:0045792; GO:0045859; GO:0045945; GO:0046777; GO:0046889; GO:0048255; GO:0048266; GO:0048511; GO:0048661; GO:0048709; GO:0048714; GO:0048738; GO:0050731; GO:0050769; GO:0050882; GO:0051219; GO:0051496; GO:0051549; GO:0051647; GO:0051896; GO:0051897; GO:0055006; GO:0055013; GO:0060048; GO:0060135; GO:0060252; GO:0060999; GO:0061051; GO:0070885; GO:0071230; GO:0071233; GO:0071456; GO:0090335; GO:0090559; GO:0098978; GO:0099524; GO:0099547; GO:0106310; GO:1901216; GO:1901838; GO:1903691; GO:1904000; GO:1904056; GO:1904058; GO:1904059; GO:1904193; GO:1904197; GO:1904206; GO:1904213; GO:1990253; GO:2000774 7841 FUN_026320 42 3 5 0 4 NA NA NA NA NA NA NA 7842 FUN_026323 351 26 44 0 6 NA NA NA NA NA NA NA 7843 FUN_004103 284 228 87 232 269 NA NA NA NA NA NA NA 7844 FUN_027059 6 2 7 23 24 NA NA NA NA NA NA NA 7845 FUN_037235 94 446 120 122 170 NA NA NA NA NA NA NA 7846 FUN_037237 27 121 122 0 0 NA NA NA NA NA NA NA 7847 FUN_037236 884 1991 531 2610 1164 NA NA NA NA NA NA NA 7848 FUN_004104 63 39 0 31 1 NA NA NA NA NA NA NA 7849 FUN_037230 1054 777 510 693 555 NA NA NA NA NA NA NA 7850 FUN_037233 557 426 705 1906 557 ptg000026l:7367909-7369214 O96024 4.43e-28 Beta-1,3-galactosyltransferase 4 (Beta-1,3-GalTase 4) (Beta3Gal-T4) (Beta3GalT4) (GalT4) (b3Gal-T4) (EC 2.4.1.62) (Gal-T2) (Ganglioside galactosyltransferase) (UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase) Homo sapiens (Human) ganglioside biosynthetic process [GO:0001574]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0001574; GO:0006486; GO:0008499; GO:0009312; GO:0016757; GO:0019901; GO:0022627; GO:0047915 7851 FUN_037232 1893 959 562 1559 982 ptg000026l:7340774-7363014 Q9QXK7 3.98e-22 Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73) Mus musculus (Mouse) mRNA 3'-end processing [GO:0031124]; mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA polyadenylation [GO:0006378]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503] GO:0003723; GO:0004521; GO:0004534; GO:0005847; GO:0006378; GO:0006398; GO:0008409; GO:0031124; GO:0046872; GO:0090503; GO:1900087; GO:1990904 7852 FUN_037232 1893 959 562 1559 982 ptg000026l:7340774-7363014 Q9QXK7 3.98e-22 Cleavage and polyadenylation specificity factor subunit 3 (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit) (CPSF 73 kDa subunit) (mRNA 3'-end-processing endonuclease CPSF-73) Mus musculus (Mouse) mRNA 3'-end processing [GO:0031124]; mRNA 3'-end processing by stem-loop binding and cleavage [GO:0006398]; mRNA polyadenylation [GO:0006378]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503] GO:0003723; GO:0004521; GO:0004534; GO:0005847; GO:0006378; GO:0006398; GO:0008409; GO:0031124; GO:0046872; GO:0090503; GO:1900087; GO:1990904 7853 FUN_037239 104 67 32 211 86 NA NA NA NA NA NA NA 7854 FUN_037238 13916 8671 4616 7579 5145 NA NA NA NA NA NA NA 7855 FUN_006734 164 30 253 285 206 ptg000001l:16017723-16022930 Q9BZP6 1.29e-32 Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902) Homo sapiens (Human) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; chitin metabolic process [GO:0006030]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] GO:0000272; GO:0002376; GO:0002532; GO:0004568; GO:0005576; GO:0005615; GO:0005737; GO:0006030; GO:0006032; GO:0006915; GO:0008061; GO:0019900; GO:0032722; GO:0044245 7856 FUN_006734 164 30 253 285 206 ptg000001l:16017723-16022930 Q9BZP6 3.52e-25 Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Lung-specific protein TSA1902) Homo sapiens (Human) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; chitin metabolic process [GO:0006030]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; polysaccharide digestion [GO:0044245]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] GO:0000272; GO:0002376; GO:0002532; GO:0004568; GO:0005576; GO:0005615; GO:0005737; GO:0006030; GO:0006032; GO:0006915; GO:0008061; GO:0019900; GO:0032722; GO:0044245 7857 FUN_006735 20 15 18 112 28 ptg000001l:16039814-16040828 G3M4F8 2.43e-23 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 7858 FUN_006736 28 25 45 54 17 NA NA NA NA NA NA NA 7859 FUN_006737 482 486 257 369 392 NA NA NA NA NA NA NA 7860 FUN_006730 582 421 171 684 209 NA NA NA NA NA NA NA 7861 FUN_006731 2722 2407 1739 1515 2322 NA NA NA NA NA NA NA 7862 FUN_006732 926 527 464 536 549 NA NA NA NA NA NA NA 7863 FUN_006733 474 157 284 239 369 NA NA NA NA NA NA NA 7864 FUN_034079 353 5 333 492 266 NA NA NA NA NA NA NA 7865 FUN_006738 3617 2751 1527 3420 2684 NA NA NA NA NA NA NA 7866 FUN_006739 2419 2333 1420 1944 164 NA NA NA NA NA NA NA 7867 FUN_026893 0 0 0 0 8 NA NA NA NA NA NA NA 7868 FUN_018467 187 170 67 280 194 NA NA NA NA NA NA NA 7869 FUN_026890 0 35 0 9 0 NA NA NA NA NA NA NA 7870 FUN_026897 1460 1261 948 1542 686 ptg000020l:14705034-14715750 P34275 6.67e-33 Probable acyl-CoA dehydrogenase 6 (Probable isovaleryl-CoA dehydrogenase) (IVD) (EC 1.3.8.4) Caenorhabditis elegans fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539]; leucine catabolic process [GO:0006552] GO:0003995; GO:0005737; GO:0006552; GO:0008470; GO:0033539; GO:0050660 7871 FUN_026896 93 41 33 17 48 NA NA NA NA NA NA NA 7872 FUN_026895 446 437 117 298 163 ptg000020l:14695781-14696702 Q9QZS6 1.31e-90 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 7873 FUN_034077 0 0 0 0 6 NA NA NA NA NA NA NA 7874 FUN_026899 1081 394 584 939 988 NA NA NA NA NA NA NA 7875 FUN_026898 100 79 137 88 128 NA NA NA NA NA NA NA 7876 FUN_034074 28 10 14 7166 4563 NA NA NA NA NA NA NA 7877 FUN_034075 434 106 148 505 419 NA NA NA NA NA NA NA 7878 FUN_034072 12 24 9 267 221 NA NA NA NA NA NA NA 7879 FUN_034073 9 89 23 70 44 NA NA NA NA NA NA NA 7880 FUN_034070 7 5 0 703 557 NA NA NA NA NA NA NA 7881 FUN_034071 17 0 0 6 151 NA NA NA NA NA NA NA 7882 FUN_032777 71 6 16 93 34 ptg000023l:35863125-35865357 P49219 6.73e-23 Melatonin receptor type 1C (Mel-1C-R) (Mel1c (alpha) receptor) (Mel1c receptor) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0008502 7883 FUN_032776 110 108 66 91 30 NA NA NA NA NA NA NA 7884 FUN_032775 49 25 55 66 33 ptg000023l:35856408-35857575 P49288 7.62e-30 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 7885 FUN_032774 360 166 121 152 262 NA NA NA NA NA NA NA 7886 FUN_032773 2579 2072 1283 2332 2193 NA NA NA NA NA NA NA 7887 FUN_032772 2364 1160 684 982 1029 NA NA NA NA NA NA NA 7888 FUN_032771 31 21 48 10 132 NA NA NA NA NA NA NA 7889 FUN_032779 44 14 0 35 0 ptg000023l:35876808-35879641 P49219 1.19e-22 Melatonin receptor type 1C (Mel-1C-R) (Mel1c (alpha) receptor) (Mel1c receptor) Xenopus laevis (African clawed frog) NA GO:0005886; GO:0008502 7890 FUN_032778 4 15 0 20 0 ptg000023l:35872766-35875069 P48040 9.69e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 7891 FUN_011456 0 0 2 0 20 NA NA NA NA NA NA NA 7892 FUN_027159 0 0 37 0 82 NA NA NA NA NA NA NA 7893 FUN_035667 4951 5795 7003 5061 2220 NA NA NA NA NA NA NA 7894 FUN_032668 59 0 29 36 0 NA NA NA NA NA NA NA 7895 FUN_004468 3025 2053 1781 2622 2401 NA NA NA NA NA NA NA 7896 FUN_004469 16457 18979 6247 11022 5054 NA NA NA NA NA NA NA 7897 FUN_004466 5449 5034 2688 3444 2081 NA NA NA NA NA NA NA 7898 FUN_004467 459 400 488 514 601 ntLink_8:23503490-23505071 Q96BR5 2.58e-27 Cytochrome c oxidase assembly factor 7 (Beta-lactamase hcp-like protein) (Respiratory chain assembly factor 1) (Sel1 repeat-containing protein 1) Homo sapiens (Human) NA GO:0005654; GO:0005739; GO:0005758 7899 FUN_004464 2355 2220 1604 2602 2428 NA NA NA NA NA NA NA 7900 FUN_004465 343 342 179 407 351 ntLink_8:23487620-23496293 Q9R012 1.22e-25 Serine/threonine-protein kinase PLK2 (EC 2.7.11.21) (Polo-like kinase 2) (PLK-2) (Serine/threonine-protein kinase SNK) (Serum-inducible kinase) Rattus norvegicus (Rat) G1/S transition of mitotic cell cycle [GO:0000082]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; mitotic cell cycle [GO:0000278]; mitotic spindle organization [GO:0007052]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic process in bone marrow cell [GO:0071866]; negative regulation of cellular senescence [GO:2000773]; negative regulation of dendritic spine development [GO:0061000]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of protein binding [GO:0032091]; negative regulation of protein localization to cell surface [GO:2000009]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein binding [GO:0032092]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of receptor internalization [GO:0002092]; protein phosphorylation [GO:0006468]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of centriole replication [GO:0046599]; regulation of cytokinesis [GO:0032465]; regulation of synaptic plasticity [GO:0048167] GO:0000082; GO:0000278; GO:0000785; GO:0000922; GO:0002092; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0006468; GO:0007052; GO:0007265; GO:0007613; GO:0010508; GO:0016525; GO:0018105; GO:0019901; GO:0030425; GO:0032050; GO:0032091; GO:0032092; GO:0032436; GO:0032465; GO:0032486; GO:0043008; GO:0043066; GO:0044877; GO:0045202; GO:0045732; GO:0046599; GO:0048167; GO:0051020; GO:0051117; GO:0060291; GO:0060292; GO:0061000; GO:0071866; GO:0090050; GO:0090394; GO:0106310; GO:2000009; GO:2000773 7901 FUN_004462 41 0 24 31 30 NA NA NA NA NA NA NA 7902 FUN_004463 18 32 26 16 11 NA NA NA NA NA NA NA 7903 FUN_004460 49 67 47 308 94 NA NA NA NA NA NA NA 7904 FUN_004461 525 359 136 375 170 ntLink_8:23464619-23465303 E7FDB3 3e-21 Nanos homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of translation [GO:0017148]; oogenesis [GO:0048477] GO:0003729; GO:0005737; GO:0008270; GO:0017148; GO:0030371; GO:0048471; GO:0048477; GO:0060293 7905 FUN_000414 0 0 4 7 0 NA NA NA NA NA NA NA 7906 FUN_002708 0 3 0 8 1 NA NA NA NA NA NA NA 7907 FUN_002705 0 0 0 68 7 NA NA NA NA NA NA NA 7908 FUN_002704 321 551 246 387 100 NA NA NA NA NA NA NA 7909 FUN_002707 118 319 153 343 94 NA NA NA NA NA NA NA 7910 FUN_002706 666 865 276 952 120 NA NA NA NA NA NA NA 7911 FUN_002701 472 291 348 126 19 NA NA NA NA NA NA NA 7912 FUN_002700 605 335 364 564 574 NA NA NA NA NA NA NA 7913 FUN_002703 2 4 0 18 4 NA NA NA NA NA NA NA 7914 FUN_006599 170 93 148 213 373 NA NA NA NA NA NA NA 7915 FUN_028433 2 0 0 95 7 NA NA NA NA NA NA NA 7916 FUN_001179 142862 100373 69574 86925 30602 NA NA NA NA NA NA NA 7917 FUN_001178 737 367 230 339 341 NA NA NA NA NA NA NA 7918 FUN_001177 1401 950 692 1149 1224 NA NA NA NA NA NA NA 7919 FUN_001176 745 187 776 889 494 NA NA NA NA NA NA NA 7920 FUN_001175 1925 722 675 847 958 ntLink_6:9374790-9377313 B0UYT5 1.08e-22 Major facilitator superfamily domain-containing protein 6-B (Macrophage MHC class I receptor 2 homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 7921 FUN_001174 229 133 179 154 150 NA NA NA NA NA NA NA 7922 FUN_001173 1419 812 562 534 661 ntLink_6:9349825-9362418 Q6XPR3 2.92e-31 Repetin Homo sapiens (Human) NA GO:0001533; GO:0005509; GO:0005576; GO:0005829; GO:0046914 7923 FUN_001172 409 170 167 278 456 NA NA NA NA NA NA NA 7924 FUN_001171 93 60 92 108 159 NA NA NA NA NA NA NA 7925 FUN_001170 4386 19385 3287 8165 4767 NA NA NA NA NA NA NA 7926 FUN_025812 64 42 15 72 95 NA NA NA NA NA NA NA 7927 FUN_025810 517 201 272 411 470 NA NA NA NA NA NA NA 7928 FUN_025811 796 389 181 439 448 NA NA NA NA NA NA NA 7929 FUN_025817 41 6 38 39 133 ptg000020l:889249-889777 Q8VHC8 9.8e-45 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Cavia porcellus (Guinea pig) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 7930 FUN_025814 1302 2368 1059 1427 989 NA NA NA NA NA NA NA 7931 FUN_028436 0 0 0 385 0 NA NA NA NA NA NA NA 7932 FUN_028435 16 0 6 7413 6 NA NA NA NA NA NA NA 7933 FUN_028434 0 0 0 94 0 NA NA NA NA NA NA NA 7934 FUN_035868 320 294 96 236 194 NA NA NA NA NA NA NA 7935 FUN_035869 424 298 206 323 265 NA NA NA NA NA NA NA 7936 FUN_035866 979 1260 984 1073 679 NA NA NA NA NA NA NA 7937 FUN_035867 457 530 262 447 161 NA NA NA NA NA NA NA 7938 FUN_035864 1385 733 677 929 1146 ptg000025l:12684436-12712712 O60231 2.89e-46 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0008380; GO:0016887; GO:0071005 7939 FUN_035864 1385 733 677 929 1146 ptg000025l:12684436-12712712 O60231 3.71e-35 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0005681; GO:0008380; GO:0016887; GO:0071005 7940 FUN_035865 1096 1211 726 1022 929 NA NA NA NA NA NA NA 7941 FUN_035862 1886 1466 1037 1817 1581 NA NA NA NA NA NA NA 7942 FUN_035863 822 1288 686 1076 2594 NA NA NA NA NA NA NA 7943 FUN_035860 41 13 12 0 0 NA NA NA NA NA NA NA 7944 FUN_035861 896 234 243 292 298 NA NA NA NA NA NA NA 7945 FUN_004288 6798 6245 6109 14655 15162 NA NA NA NA NA NA NA 7946 FUN_004289 17125 11861 8790 28177 20775 NA NA NA NA NA NA NA 7947 FUN_004282 2850 2260 494 1734 1544 NA NA NA NA NA NA NA 7948 FUN_004283 2321 2022 1513 1655 1696 NA NA NA NA NA NA NA 7949 FUN_004280 748 873 439 756 481 NA NA NA NA NA NA NA 7950 FUN_004281 661 233 393 622 558 NA NA NA NA NA NA NA 7951 FUN_004286 280 202 187 331 415 ntLink_8:21530508-21533427 Q6NU91 4.95e-103 Nucleolar complex protein 4 homolog B (NOC4 protein homolog B) (NOC4-like protein B) (Nucleolar complex-associated protein 4-like protein B) Xenopus laevis (African clawed frog) ribosome biogenesis [GO:0042254] GO:0005730; GO:0031965; GO:0042254 7952 FUN_004287 304 294 76 154 80 NA NA NA NA NA NA NA 7953 FUN_004284 326 272 108 150 134 ntLink_8:21500897-21502480 Q9V576 2.36e-28 Putative phosphatidate phosphatase (EC 3.1.3.4) (Germ cell guidance factor) (Phosphatidic acid phosphatase type 2) (Protein wunen) Drosophila melanogaster (Fruit fly) defense response to Gram-negative bacterium [GO:0050829]; ectopic germ cell programmed cell death [GO:0035234]; germ cell migration [GO:0008354]; germ cell repulsion [GO:0035233]; negative regulation of innate immune response [GO:0045824]; open tracheal system development [GO:0007424]; phospholipid dephosphorylation [GO:0046839]; phospholipid metabolic process [GO:0006644]; pole cell migration [GO:0007280]; septate junction assembly [GO:0019991]; signal transduction [GO:0007165] GO:0005886; GO:0005918; GO:0006644; GO:0007165; GO:0007280; GO:0007424; GO:0008195; GO:0008354; GO:0016791; GO:0019991; GO:0035233; GO:0035234; GO:0042577; GO:0045177; GO:0045824; GO:0046839; GO:0050829 7954 FUN_004285 8031 5028 3648 22625 15672 NA NA NA NA NA NA NA 7955 FUN_022375 2988 2534 1189 4138 3297 NA NA NA NA NA NA NA 7956 FUN_040958 434 458 250 307 197 NA NA NA NA NA NA NA 7957 FUN_040959 20 0 16 23 10 NA NA NA NA NA NA NA 7958 FUN_040956 1956 950 549 780 744 ptg000033l:468543-478866 Q6PBT5 7.56e-98 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0016491; GO:0030017; GO:0050660 7959 FUN_040957 1005 564 577 716 456 ptg000033l:478958-480683 Q9CQ02 3.94e-66 COMM domain-containing protein 4 Mus musculus (Mouse) NA GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0043231 7960 FUN_040954 2509 1148 835 1813 1606 NA NA NA NA NA NA NA 7961 FUN_040955 6377 3447 2733 3516 3534 NA NA NA NA NA NA NA 7962 FUN_040952 915 1123 561 648 1190 NA NA NA NA NA NA NA 7963 FUN_040950 1303 1450 931 1694 868 NA NA NA NA NA NA NA 7964 FUN_040951 9 10 11 1 10 NA NA NA NA NA NA NA 7965 FUN_012560 5618 4623 2685 3613 2951 NA NA NA NA NA NA NA 7966 FUN_012561 1389 779 637 974 1063 ptg000008l:9920219-9932080 Q9R0X5 4.5e-35 X-linked retinitis pigmentosa GTPase regulator (mRpgr) Mus musculus (Mouse) cellular response to light stimulus [GO:0071482]; cilium assembly [GO:0060271]; eye photoreceptor cell development [GO:0042462]; intraciliary transport [GO:0042073]; retina morphogenesis in camera-type eye [GO:0060042]; visual perception [GO:0007601] GO:0001750; GO:0005085; GO:0005737; GO:0005794; GO:0005813; GO:0005929; GO:0007601; GO:0032391; GO:0036064; GO:0036126; GO:0042073; GO:0042462; GO:0042995; GO:0060042; GO:0060271; GO:0071482; GO:0120206 7967 FUN_012563 1464 495 545 877 681 NA NA NA NA NA NA NA 7968 FUN_012564 24 63 26 30 67 NA NA NA NA NA NA NA 7969 FUN_012565 57 0 41 21 126 NA NA NA NA NA NA NA 7970 FUN_012566 6 0 13 0 36 NA NA NA NA NA NA NA 7971 FUN_012567 5045 2317 2442 9709 2317 NA NA NA NA NA NA NA 7972 FUN_012568 84 33 0 51 0 NA NA NA NA NA NA NA 7973 FUN_016270 94 221 95 650 454 NA NA NA NA NA NA NA 7974 FUN_016271 86 36 18 268 363 NA NA NA NA NA NA NA 7975 FUN_016274 282 145 199 624 764 NA NA NA NA NA NA NA 7976 FUN_016275 105 28 108 199 472 NA NA NA NA NA NA NA 7977 FUN_016276 96 56 101 192 408 NA NA NA NA NA NA NA 7978 FUN_016277 46 115 77 133 279 NA NA NA NA NA NA NA 7979 FUN_003157 6 30 0 0 0 NA NA NA NA NA NA NA 7980 FUN_003156 47 18 0 6 39 NA NA NA NA NA NA NA 7981 FUN_007094 16 20 0 42 11 NA NA NA NA NA NA NA 7982 FUN_028008 650 426 429 564 558 ptg000021l:14536847-14545750 Q9WTS8 1.48e-52 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 7983 FUN_028009 0 0 0 8 0 NA NA NA NA NA NA NA 7984 FUN_028006 110 81 81 39 83 NA NA NA NA NA NA NA 7985 FUN_028007 544 473 257 434 489 NA NA NA NA NA NA NA 7986 FUN_028004 2295 2257 1399 1848 1065 NA NA NA NA NA NA NA 7987 FUN_028005 2340 5376 1100 1582 1424 ptg000021l:14495252-14504386 P04323 2.56e-74 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 7988 FUN_028002 457 912 275 788 1429 ptg000021l:14477565-14487386 Q92051 2.41e-57 Carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Danio rerio (Zebrafish) (Brachydanio rerio) carbon dioxide transport [GO:0015670]; hypotonic salinity response [GO:0042539]; one-carbon metabolic process [GO:0006730] GO:0004089; GO:0005737; GO:0006730; GO:0008270; GO:0015670; GO:0016836; GO:0042539 7989 FUN_028000 2530 2627 1720 2938 2122 NA NA NA NA NA NA NA 7990 FUN_028001 435 172 237 224 344 ptg000021l:14462921-14469707 Q9BRR8 4.1e-43 G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0071013 7991 FUN_028001 435 172 237 224 344 ptg000021l:14462921-14469707 Q9BRR8 6.3e-29 G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0005634; GO:0071013 7992 FUN_036881 3459 2339 1878 3567 3388 ptg000026l:3037172-3061474 Q8BGI4 9.25e-23 Protein FAM13A (Precm1 protein) Mus musculus (Mouse) NA NA 7993 FUN_036880 63 7 47 12 199 NA NA NA NA NA NA NA 7994 FUN_036882 1521 837 593 1043 614 NA NA NA NA NA NA NA 7995 FUN_036887 417 188 283 381 332 NA NA NA NA NA NA NA 7996 FUN_036886 52 253 37 89 113 NA NA NA NA NA NA NA 7997 FUN_036889 867 892 504 1126 658 ptg000026l:3128932-3131022 Q3SYV5 1.27e-65 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 7998 FUN_036888 5985 4434 3114 4947 3150 NA NA NA NA NA NA NA 7999 FUN_041588 476 1115 524 619 371 NA NA NA NA NA NA NA 8000 FUN_041589 2 588 0 6 65 ptg000035l:5544689-5545577 Q4SBY6 3.64e-21 Histamine N-methyltransferase (HMT) (EC 2.1.1.8) Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis) histamine catabolic process [GO:0001695]; methylation [GO:0032259] GO:0001695; GO:0005737; GO:0032259; GO:0046539 8001 FUN_041331 46 0 0 42 0 NA NA NA NA NA NA NA 8002 FUN_019804 0 0 11 0 18 NA NA NA NA NA NA NA 8003 FUN_002289 0 0 0 0 7 NA NA NA NA NA NA NA 8004 FUN_007093 10 10 78 21 47 NA NA NA NA NA NA NA 8005 FUN_019805 4 0 6 3 126 NA NA NA NA NA NA NA 8006 FUN_002280 13 1 33 1 150 ntLink_6:23138891-23139203 Q6LAF1 2.06e-51 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 8007 FUN_019802 0 0 1 0 25 ptg000015l:5969874-5978668 O00370 3.02e-42 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 8008 FUN_019802 0 0 1 0 25 ptg000015l:5969874-5978668 O00370 3.02e-42 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 8009 FUN_019802 0 0 1 0 25 ptg000015l:5969874-5978668 O00370 3.02e-42 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 8010 FUN_002282 0 0 0 0 9 NA NA NA NA NA NA NA 8011 FUN_041587 1994 2095 932 1859 1528 NA NA NA NA NA NA NA 8012 FUN_043790 0 0 0 18 0 ptg000049l:1073436-1074859 O22034 2.38e-26 Protein CfxQ homolog Cyanidium caldarium (Red alga) NA GO:0005524; GO:0009507; GO:0016887 8013 FUN_043795 0 23 48 0 31 NA NA NA NA NA NA NA 8014 FUN_043797 0 0 5 7 4 NA NA NA NA NA NA NA 8015 FUN_013865 0 0 1 7 6 NA NA NA NA NA NA NA 8016 FUN_042440 24 6 0 0 0 NA NA NA NA NA NA NA 8017 FUN_013761 30 0 0 0 13 NA NA NA NA NA NA NA 8018 FUN_013760 36 0 7 19 11 NA NA NA NA NA NA NA 8019 FUN_013763 9 0 3 0 183 NA NA NA NA NA NA NA 8020 FUN_013855 0 90 0 0 0 NA NA NA NA NA NA NA 8021 FUN_009161 12 22 1 22 35 NA NA NA NA NA NA NA 8022 FUN_009162 39 0 18 0 0 NA NA NA NA NA NA NA 8023 FUN_023295 29 624 337 312 333 ptg000017l:6006264-6018675 A0A2B4SJA1 2.13e-76 NA NA NA NA 8024 FUN_022729 127 22 65 44 62 ptg000016l:12688058-12690060 P25291 1.1e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 8025 FUN_022729 127 22 65 44 62 ptg000016l:12688058-12690060 P25291 1.1e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 8026 FUN_009166 1152 128 91 1076 267 ptg000004l:3418631-3423861 Q96AY4 3.72e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8027 FUN_009166 1152 128 91 1076 267 ptg000004l:3418631-3423861 Q96AY4 3.2e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8028 FUN_009166 1152 128 91 1076 267 ptg000004l:3418631-3423861 Q96AY4 2.68e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8029 FUN_009166 1152 128 91 1076 267 ptg000004l:3418631-3423861 Q96AY4 4.6e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8030 FUN_009166 1152 128 91 1076 267 ptg000004l:3418631-3423861 Q96AY4 2.5e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8031 FUN_022725 62 18 34 18 34 ptg000016l:12683584-12684470 P25291 1.07e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 8032 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 7.45e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8033 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 3.01e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8034 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 5.25e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8035 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 4.64e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8036 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 3e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8037 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 1.53e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8038 FUN_009169 170 223 155 123 113 ptg000004l:3479222-3490224 Q96AY4 1.89e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8039 FUN_022727 54 17 28 14 24 ptg000016l:12685820-12686706 Q6V0K7 4.97e-27 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 8040 FUN_022726 74 15 27 23 39 ptg000016l:12684702-12685588 P25291 1.07e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 8041 FUN_022721 19 48 15 38 21 NA NA NA NA NA NA NA 8042 FUN_022720 24 38 51 46 26 NA NA NA NA NA NA NA 8043 FUN_022722 3845 3215 1842 3298 2675 NA NA NA NA NA NA NA 8044 FUN_023290 1120 76 213 64 109 NA NA NA NA NA NA NA 8045 FUN_029841 31 0 4 17 28 NA NA NA NA NA NA NA 8046 FUN_029840 717 811 82 1005 1136 NA NA NA NA NA NA NA 8047 FUN_029847 0 0 6 0 13 NA NA NA NA NA NA NA 8048 FUN_029848 0 0 0 0 16 NA NA NA NA NA NA NA 8049 FUN_022097 1706 1269 650 1659 822 NA NA NA NA NA NA NA 8050 FUN_022096 135 256 123 166 115 NA NA NA NA NA NA NA 8051 FUN_022095 1509 398 518 2086 572 NA NA NA NA NA NA NA 8052 FUN_022094 3190 1915 1263 4494 1438 NA NA NA NA NA NA NA 8053 FUN_022093 1116 1214 661 779 480 NA NA NA NA NA NA NA 8054 FUN_022092 49 32 0 23 40 NA NA NA NA NA NA NA 8055 FUN_022091 8 0 20 0 47 NA NA NA NA NA NA NA 8056 FUN_022099 0 0 8 5 3 NA NA NA NA NA NA NA 8057 FUN_022098 383 189 223 303 284 ptg000016l:5402079-5411093 P19538 1.65e-25 Transcriptional activator cubitus interruptus (Transcriptional activator ci) (ci form of 155 kDa) (ci-155) (ci full-length protein) (ciFL) [Cleaved into: Transcriptional repressor cubitus interruptus (Transcriptional repressor ci) (ci C-terminally truncated form) (ci form of 75 kDa) (ci-75)] Drosophila melanogaster (Fruit fly) compound eye morphogenesis [GO:0001745]; cuticle pattern formation [GO:0035017]; dendrite morphogenesis [GO:0048813]; genital disc anterior/posterior pattern formation [GO:0035224]; heart formation [GO:0060914]; labial disc development [GO:0035217]; mucosal immune response [GO:0002385]; negative regulation of hippo signaling [GO:0035331]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell proliferation involved in compound eye morphogenesis [GO:2000495]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357]; segment polarity determination [GO:0007367]; smoothened signaling pathway [GO:0007224]; spiracle morphogenesis, open tracheal system [GO:0035277]; wing disc anterior/posterior pattern formation [GO:0048100] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001745; GO:0002385; GO:0003677; GO:0005634; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0007224; GO:0007346; GO:0007367; GO:0008140; GO:0019901; GO:0030858; GO:0032991; GO:0035017; GO:0035217; GO:0035224; GO:0035277; GO:0035301; GO:0035331; GO:0042802; GO:0042803; GO:0043565; GO:0045944; GO:0046872; GO:0048100; GO:0048813; GO:0060914; GO:1900087; GO:2000495 8058 FUN_040178 9 0 0 35 8 NA NA NA NA NA NA NA 8059 FUN_040179 0 165 21 0 0 NA NA NA NA NA NA NA 8060 FUN_040171 1494 909 733 1849 1602 NA NA NA NA NA NA NA 8061 FUN_040172 1005 729 759 1468 1211 NA NA NA NA NA NA NA 8062 FUN_040173 747 433 287 480 563 NA NA NA NA NA NA NA 8063 FUN_040174 86 0 0 0 0 NA NA NA NA NA NA NA 8064 FUN_040177 0 0 0 22 0 NA NA NA NA NA NA NA 8065 FUN_007166 299 128 249 793 476 NA NA NA NA NA NA NA 8066 FUN_043321 926 517 518 790 1199 ptg000047l:7043865-7069644 Q92072 3.05e-39 DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT) Gallus gallus (Chicken) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] GO:0003677; GO:0003886; GO:0005634; GO:0008270; GO:0090309; GO:1990841 8067 FUN_043321 926 517 518 790 1199 ptg000047l:7043865-7069644 Q92072 1.98e-22 DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT) Gallus gallus (Chicken) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] GO:0003677; GO:0003886; GO:0005634; GO:0008270; GO:0090309; GO:1990841 8068 FUN_043321 926 517 518 790 1199 ptg000047l:7043865-7069644 Q92072 8.16e-21 DNA (cytosine-5)-methyltransferase 1 (Dnmt1) (EC 2.1.1.37) (DNA methyltransferase GgaI) (DNA MTase GgaI) (M.GgaI) (MCMT) Gallus gallus (Chicken) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309] GO:0003677; GO:0003886; GO:0005634; GO:0008270; GO:0090309; GO:1990841 8069 FUN_007164 196 70 128 250 387 NA NA NA NA NA NA NA 8070 FUN_015217 456 300 212 231 240 NA NA NA NA NA NA NA 8071 FUN_015216 2168 2169 1376 2082 2136 ptg000009l:7566630-7583798 Q58DM4 1.96e-78 DNA oxidative demethylase ALKBH2 (EC 1.14.11.33) (Alkylated DNA repair protein alkB homolog 2) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2) Bos taurus (Bovine) DNA dealkylation involved in DNA repair [GO:0006307]; oxidative DNA demethylation [GO:0035511] GO:0000182; GO:0005654; GO:0005730; GO:0006307; GO:0008198; GO:0035511; GO:0035516; GO:0043734; GO:0051747 8072 FUN_015215 835 0 610 270 295 ptg000009l:7551836-7561173 Q8CG08 7.46e-30 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 8073 FUN_015215 835 0 610 270 295 ptg000009l:7551836-7561173 Q8CG08 2.09e-27 Collagen triple helix repeat-containing protein 1 Rattus norvegicus (Rat) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005581; GO:0005615; GO:0005737; GO:0016477; GO:0016528; GO:0017147; GO:0031012; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0090090; GO:0090103; GO:0090177 8074 FUN_015214 189 74 102 107 0 ptg000009l:7543116-7543835 Q96CG8 9.16e-28 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 8075 FUN_015213 31 341 225 591 20 ptg000009l:7524962-7537359 Q96CG8 1.76e-31 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 8076 FUN_015213 31 341 225 591 20 ptg000009l:7524962-7537359 Q96CG8 1.1e-30 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 8077 FUN_015212 10 0 0 0 0 NA NA NA NA NA NA NA 8078 FUN_015210 75 0 87 0 0 NA NA NA NA NA NA NA 8079 FUN_007162 271 180 358 500 263 NA NA NA NA NA NA NA 8080 FUN_015219 2274 971 880 974 1185 ptg000009l:7587314-7598674 B0JZ65 1.59e-23 Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin organization [GO:0006325]; DNA replication [GO:0006260]; establishment of protein localization to chromatin [GO:0071169] GO:0000776; GO:0000781; GO:0003682; GO:0005634; GO:0005664; GO:0005721; GO:0005737; GO:0005815; GO:0006260; GO:0006325; GO:0008327; GO:0035064; GO:0071169 8081 FUN_015218 85 165 74 116 116 ptg000009l:7585987-7586963 Q9NXW9 1.77e-58 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; chromatin organization [GO:0006325]; cleavage furrow ingression [GO:0036090]; DNA demethylation [GO:0080111]; oxidative demethylation [GO:0070989]; protein demethylation [GO:0006482]; regulation of chromatin organization [GO:1902275] GO:0003779; GO:0005730; GO:0005737; GO:0006325; GO:0006482; GO:0016491; GO:0016706; GO:0030496; GO:0031032; GO:0032451; GO:0035516; GO:0036090; GO:0046872; GO:0070938; GO:0070989; GO:0080111; GO:1902275 8082 FUN_007160 8586 10999 4797 9534 6057 NA NA NA NA NA NA NA 8083 FUN_043327 6199 2726 698 1424 1412 ptg000047l:7150573-7161895 Q99MQ3 1.19e-22 Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1) Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; catecholamine secretion [GO:0050432]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; dopamine secretion [GO:0014046]; establishment of localization in cell [GO:0051649]; establishment of protein localization to mitochondrion [GO:0072655]; hemopoiesis [GO:0030097]; intracellular signal transduction [GO:0035556]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of catecholamine secretion [GO:0033605]; positive regulation of cristae formation [GO:1903852]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neuron apoptotic process [GO:0043523]; regulation of oxidative phosphorylation [GO:0002082]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of protein-containing complex assembly [GO:0043254]; regulation of reactive oxygen species metabolic process [GO:2000377]; respiratory electron transport chain [GO:0022904]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979] GO:0000287; GO:0000422; GO:0000423; GO:0000785; GO:0001934; GO:0002020; GO:0002082; GO:0002931; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005758; GO:0005783; GO:0005829; GO:0005856; GO:0006468; GO:0006979; GO:0007005; GO:0010310; GO:0010629; GO:0010821; GO:0010857; GO:0014046; GO:0016020; GO:0016239; GO:0016242; GO:0016301; GO:0016567; GO:0018105; GO:0022904; GO:0030097; GO:0030424; GO:0030426; GO:0031396; GO:0031625; GO:0032226; GO:0033138; GO:0033603; GO:0033605; GO:0034599; GO:0035307; GO:0035556; GO:0036289; GO:0042981; GO:0043066; GO:0043123; GO:0043254; GO:0043422; GO:0043523; GO:0043524; GO:0044297; GO:0044877; GO:0045727; GO:0048471; GO:0050432; GO:0050821; GO:0051091; GO:0051649; GO:0051881; GO:0055131; GO:0071456; GO:0072655; GO:0072656; GO:0090141; GO:0090200; GO:0090258; GO:0097237; GO:0097449; GO:0098779; GO:0099074; GO:0106310; GO:1900407; GO:1901215; GO:1901525; GO:1901727; GO:1902902; GO:1902958; GO:1903202; GO:1903214; GO:1903298; GO:1903384; GO:1903751; GO:1903852; GO:1904783; GO:1904841; GO:1904881; GO:1904925; GO:2000377; GO:2000378; GO:2001243 8084 FUN_032438 0 90 74 88 88 NA NA NA NA NA NA NA 8085 FUN_032439 297 153 53 97 81 NA NA NA NA NA NA NA 8086 FUN_032434 18 20 48 28 159 NA NA NA NA NA NA NA 8087 FUN_032436 81 50 28 33 97 ptg000023l:31913276-31917027 Q6V0K7 2.54e-23 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 8088 FUN_032437 157 332 18 105 152 ptg000023l:31928954-31965332 P14381 9.95e-101 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 8089 FUN_032430 67 47 97 76 90 NA NA NA NA NA NA NA 8090 FUN_032431 436 321 412 617 676 ptg000023l:31865408-31871694 Q3T058 2.56e-37 Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) Bos taurus (Bovine) myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0001541; GO:0003743; GO:0005737; GO:0005851; GO:0006413; GO:0014003; GO:0042552; GO:0050852 8091 FUN_032431 436 321 412 617 676 ptg000023l:31865408-31871694 Q3T058 2.56e-37 Translation initiation factor eIF-2B subunit delta (eIF-2B GDP-GTP exchange factor subunit delta) Bos taurus (Bovine) myelination [GO:0042552]; oligodendrocyte development [GO:0014003]; ovarian follicle development [GO:0001541]; T cell receptor signaling pathway [GO:0050852]; translational initiation [GO:0006413] GO:0001541; GO:0003743; GO:0005737; GO:0005851; GO:0006413; GO:0014003; GO:0042552; GO:0050852 8092 FUN_032432 0 15 48 41 28 ptg000023l:31874274-31877857 Q7ZWG6 4.88e-45 Proton-coupled folate transporter (Solute carrier family 46 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005542; GO:0005768; GO:0005886; GO:0010008; GO:0015293; GO:0015350; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0055085 8093 FUN_032433 379 109 354 614 605 NA NA NA NA NA NA NA 8094 FUN_028828 28 0 0 0 0 NA NA NA NA NA NA NA 8095 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 1.48e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8096 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 1.92e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8097 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 7.25e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8098 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 5.4e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8099 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 2.3e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8100 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 2.34e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8101 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 4.2e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8102 FUN_028829 193 29 131 167 13 ptg000022l:4696661-4702958 Q96AY4 3.28e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8103 FUN_028820 44 0 22 0 67 NA NA NA NA NA NA NA 8104 FUN_028821 204 293 222 209 165 NA NA NA NA NA NA NA 8105 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8106 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 3.07e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8107 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 3.07e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8108 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 4.1e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8109 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 7.57e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8110 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 1.05e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8111 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 1.47e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8112 FUN_028824 395 268 187 357 153 ptg000022l:4618014-4642121 Q96AY4 4.12e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8113 FUN_028825 92 33 23 91 22 ptg000022l:4657937-4664021 Q96AY4 7.19e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8114 FUN_028825 92 33 23 91 22 ptg000022l:4657937-4664021 Q96AY4 5.16e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8115 FUN_028825 92 33 23 91 22 ptg000022l:4657937-4664021 Q96AY4 5.52e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8116 FUN_028825 92 33 23 91 22 ptg000022l:4657937-4664021 Q96AY4 2.69e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8117 FUN_028825 92 33 23 91 22 ptg000022l:4657937-4664021 Q96AY4 1.41e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8118 FUN_028825 92 33 23 91 22 ptg000022l:4657937-4664021 Q96AY4 1.51e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8119 FUN_028826 0 0 13 0 0 NA NA NA NA NA NA NA 8120 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 4.77e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8121 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 1.95e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8122 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 2.54e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8123 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 4.25e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8124 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 2.22e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8125 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 4.87e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8126 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 6.29e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8127 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 3.01e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8128 FUN_028827 796 125 658 1053 35 ptg000022l:4681298-4692488 Q96AY4 1.67e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8129 FUN_041498 7596 10892 5807 19117 8555 ptg000035l:4378556-4391777 Q6Q2B2 6.76e-23 Muscleblind-like protein 2a (Tmbnl2a) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0005634; GO:0005737; GO:0006397; GO:0008380; GO:0046872 8130 FUN_041499 506 357 185 312 228 NA NA NA NA NA NA NA 8131 FUN_041494 5289 3207 1989 3327 2345 NA NA NA NA NA NA NA 8132 FUN_041495 1373 736 926 1064 1445 ptg000035l:4325660-4340507 Q91WR3 1.51e-28 Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100) Mus musculus (Mouse) DNA repair [GO:0006281]; regulation of DNA-templated transcription [GO:0006355]; rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005634; GO:0006281; GO:0006355; GO:0016607; GO:0043130; GO:0072344; GO:0099053; GO:1990116; GO:1990391 8133 FUN_041496 13989 13232 8282 11387 12656 ptg000035l:4340850-4345562 Q8ISN9 6.76e-35 40S ribosomal protein S25 Branchiostoma belcheri (Amphioxus) NA GO:0005840; GO:1990904 8134 FUN_041497 5927 4366 3121 4457 3920 NA NA NA NA NA NA NA 8135 FUN_041490 1441 1193 949 1341 937 ptg000035l:4274791-4283821 G8XYX6 3.72e-23 Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; locomotion [GO:0040011]; neuron differentiation [GO:0030182]; oligodendrocyte differentiation [GO:0048709]; Schwann cell differentiation [GO:0014037]; spinal cord development [GO:0021510]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; thyroid gland development [GO:0030878] GO:0007417; GO:0007420; GO:0014037; GO:0015349; GO:0016324; GO:0021510; GO:0021529; GO:0030182; GO:0030878; GO:0040011; GO:0043009; GO:0048709; GO:0070324 8136 FUN_041491 14 6 25 88 18 NA NA NA NA NA NA NA 8137 FUN_041492 0 0 8 0 113 ptg000035l:4300206-4303668 A1L1W9 4.13e-29 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 8138 FUN_041493 32 0 15 5 31 ptg000035l:4307791-4309144 P16388 1.11e-70 Potassium voltage-gated channel subfamily A member 1 (MBK1) (MKI) (Voltage-gated potassium channel subunit Kv1.1) Mus musculus (Mouse) axon development [GO:0061564]; brain development [GO:0007420]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005783; GO:0005829; GO:0005886; GO:0006937; GO:0007405; GO:0007420; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030424; GO:0030425; GO:0031410; GO:0033270; GO:0034705; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 8139 FUN_014223 0 161 43 0 0 NA NA NA NA NA NA NA 8140 FUN_044142 0 0 0 0 21 NA NA NA NA NA NA NA 8141 FUN_044145 51 160 69 138 358 NA NA NA NA NA NA NA 8142 FUN_014224 17 0 13 26 23 NA NA NA NA NA NA NA 8143 FUN_019611 2 24 12 2 9 NA NA NA NA NA NA NA 8144 FUN_005998 260 43 149 277 123 ptg000001l:6612157-6614101 P23780 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Mus musculus (Mouse) cellular carbohydrate metabolic process [GO:0044262]; galactose catabolic process [GO:0019388]; response to cortisone [GO:0051413]; response to Thyroglobulin triiodothyronine [GO:1904016] GO:0004565; GO:0005615; GO:0005737; GO:0005764; GO:0005773; GO:0005794; GO:0016787; GO:0016936; GO:0019388; GO:0042803; GO:0043231; GO:0044262; GO:0051413; GO:1904016 8145 FUN_044149 14 20 19 25 64 NA NA NA NA NA NA NA 8146 FUN_014228 21 0 0 0 0 NA NA NA NA NA NA NA 8147 FUN_015965 0 0 7 0 21 NA NA NA NA NA NA NA 8148 FUN_015964 0 27 0 0 6 NA NA NA NA NA NA NA 8149 FUN_015966 0 0 0 0 10 NA NA NA NA NA NA NA 8150 FUN_015963 0 0 0 0 156 NA NA NA NA NA NA NA 8151 FUN_015962 0 0 0 9 0 NA NA NA NA NA NA NA 8152 FUN_039303 76 64 0 193 59 NA NA NA NA NA NA NA 8153 FUN_039302 210 850 220 234 139 NA NA NA NA NA NA NA 8154 FUN_039301 26 33 0 59 38 NA NA NA NA NA NA NA 8155 FUN_039305 0 17 0 0 0 NA NA NA NA NA NA NA 8156 FUN_039304 15 57 0 29 32 NA NA NA NA NA NA NA 8157 FUN_007987 0 0 0 3 12 NA NA NA NA NA NA NA 8158 FUN_001066 1255 615 267 350 491 NA NA NA NA NA NA NA 8159 FUN_001061 712 336 329 695 501 ntLink_6:8026406-8044201 P23606 4.15e-22 Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; keratinization [GO:0031424]; keratinocyte differentiation [GO:0030216]; peptide cross-linking [GO:0018149]; positive regulation of cell cycle [GO:0045787]; positive regulation of keratinocyte proliferation [GO:0010838] GO:0003810; GO:0005912; GO:0009887; GO:0010838; GO:0016020; GO:0018149; GO:0030216; GO:0031424; GO:0042802; GO:0045787; GO:0046872 8160 FUN_001060 15 1 2 0 13 NA NA NA NA NA NA NA 8161 FUN_033535 0 9 0 0 12 NA NA NA NA NA NA NA 8162 FUN_004684 25 18 3 6 33 NA NA NA NA NA NA NA 8163 FUN_017187 2 6 0 11 0 NA NA NA NA NA NA NA 8164 FUN_004685 2 0 0 0 28 NA NA NA NA NA NA NA 8165 FUN_001069 159 96 125 133 130 NA NA NA NA NA NA NA 8166 FUN_017189 13 1 38 4 11 NA NA NA NA NA NA NA 8167 FUN_017188 9 0 12 14 26 NA NA NA NA NA NA NA 8168 FUN_004683 2 19 25 31 11 NA NA NA NA NA NA NA 8169 FUN_009502 190 39 18 82 37 NA NA NA NA NA NA NA 8170 FUN_007655 41 9 20 0 207 NA NA NA NA NA NA NA 8171 FUN_012609 0 0 0 0 20 NA NA NA NA NA NA NA 8172 FUN_012608 778 638 557 526 541 NA NA NA NA NA NA NA 8173 FUN_017239 23 4 47 4 187 NA NA NA NA NA NA NA 8174 FUN_017238 0 0 0 0 23 NA NA NA NA NA NA NA 8175 FUN_017237 3 0 0 0 28 NA NA NA NA NA NA NA 8176 FUN_017236 229 295 204 491 688 NA NA NA NA NA NA NA 8177 FUN_017235 188 195 140 112 47 NA NA NA NA NA NA NA 8178 FUN_017234 0 0 5 0 48 NA NA NA NA NA NA NA 8179 FUN_012605 439 1499 950 2554 982 NA NA NA NA NA NA NA 8180 FUN_017231 25 0 9 10 9 NA NA NA NA NA NA NA 8181 FUN_009500 0 11 0 0 0 NA NA NA NA NA NA NA 8182 FUN_038950 8 4 0 0 8 NA NA NA NA NA NA NA 8183 FUN_038954 54 0 0 0 89 NA NA NA NA NA NA NA 8184 FUN_041795 16 0 0 0 0 NA NA NA NA NA NA NA 8185 FUN_027969 57 0 15 0 61 NA NA NA NA NA NA NA 8186 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8187 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 1.3e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8188 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 1.03e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8189 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 8.45e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8190 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 3.09e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8191 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 2.05e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8192 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 8.63e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8193 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 3.85e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8194 FUN_027960 2426 1223 850 1594 1352 ptg000021l:13877113-13966788 Q96AY4 1.17e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8195 FUN_027961 10692 5416 3795 10085 5574 ptg000021l:13971618-13985568 P70619 2.13e-32 Glutathione reductase (GR) (GRase) (EC 1.8.1.7) Rattus norvegicus (Rat) aging [GO:0007568]; cell redox homeostasis [GO:0045454]; cellular oxidant detoxification [GO:0098869]; cellular response to oxidative stress [GO:0034599]; glutathione metabolic process [GO:0006749]; response to activity [GO:0014823]; response to cadmium ion [GO:0046686]; response to ethanol [GO:0045471]; response to iron(III) ion [GO:0010041]; response to ischemia [GO:0002931]; response to nicotine [GO:0035094]; response to oxidative stress [GO:0006979]; response to vitamin A [GO:0033189]; spermatogenesis [GO:0007283] GO:0002931; GO:0004362; GO:0005739; GO:0005829; GO:0006749; GO:0006979; GO:0007283; GO:0007568; GO:0009897; GO:0010041; GO:0014823; GO:0033189; GO:0034599; GO:0035094; GO:0042802; GO:0043295; GO:0045454; GO:0045471; GO:0046686; GO:0050660; GO:0050661; GO:0098869 8196 FUN_027962 1276 1089 833 1452 1640 NA NA NA NA NA NA NA 8197 FUN_027963 5950 3139 2212 4029 1362 ptg000021l:14001360-14003673 Q99M51 5.38e-61 Cytoplasmic protein NCK1 (NCK adaptor protein 1) (Nck-1) Mus musculus (Mouse) actin filament organization [GO:0007015]; cell migration [GO:0016477]; ephrin receptor signaling pathway [GO:0048013]; lamellipodium assembly [GO:0030032]; negative regulation of cell death [GO:0060548]; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation [GO:1903912]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of PERK-mediated unfolded protein response [GO:1903898]; negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [GO:1990441]; peptidyl-serine dephosphorylation [GO:0070262]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cap-dependent translational initiation [GO:1903676]; positive regulation of cap-independent translational initiation [GO:1903679]; positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation in response to endoplasmic reticulum stress [GO:0036493]; regulation of cell migration [GO:0030334]; response to other organism [GO:0051707]; signal transduction [GO:0007165]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell activation [GO:0042110] GO:0000164; GO:0004860; GO:0005102; GO:0005634; GO:0005737; GO:0005783; GO:0005829; GO:0005840; GO:0005886; GO:0005911; GO:0006930; GO:0007015; GO:0007165; GO:0010976; GO:0012506; GO:0016477; GO:0019904; GO:0030032; GO:0030334; GO:0030674; GO:0030838; GO:0030971; GO:0033137; GO:0035591; GO:0036493; GO:0042102; GO:0042110; GO:0045944; GO:0046627; GO:0046875; GO:0048013; GO:0051707; GO:0060548; GO:0070262; GO:0071074; GO:0140693; GO:1902237; GO:1903676; GO:1903679; GO:1903898; GO:1903912; GO:1990441 8198 FUN_027964 0 0 23 18 0 NA NA NA NA NA NA NA 8199 FUN_027965 503 391 497 936 431 NA NA NA NA NA NA NA 8200 FUN_027966 323 478 110 298 108 NA NA NA NA NA NA NA 8201 FUN_027967 918 902 441 641 509 NA NA NA NA NA NA NA 8202 FUN_014768 767 914 703 744 626 NA NA NA NA NA NA NA 8203 FUN_014769 582 672 644 560 296 NA NA NA NA NA NA NA 8204 FUN_014764 2237 1761 1208 2247 2017 ptg000009l:2870937-2876191 P13019 3.48e-44 Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) Oryctolagus cuniculus (Rabbit) proteolysis [GO:0006508] GO:0004197; GO:0005737; GO:0006508 8205 FUN_014765 3641 1972 2029 3888 3255 NA NA NA NA NA NA NA 8206 FUN_014766 107 112 116 139 54 ptg000009l:2890574-2892507 O88199 1.15e-26 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005794; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 8207 FUN_014767 180 136 228 191 60 NA NA NA NA NA NA NA 8208 FUN_014760 198 166 16 141 208 NA NA NA NA NA NA NA 8209 FUN_014761 0 0 12 0 13 NA NA NA NA NA NA NA 8210 FUN_014762 21 9 2 16 18 NA NA NA NA NA NA NA 8211 FUN_014763 0 40 38 31 17 NA NA NA NA NA NA NA 8212 FUN_026400 1815 1451 574 1670 1337 NA NA NA NA NA NA NA 8213 FUN_023433 666 352 238 577 300 NA NA NA NA NA NA NA 8214 FUN_023430 40 0 19 59 11 NA NA NA NA NA NA NA 8215 FUN_023431 133 425 210 1829 197 NA NA NA NA NA NA NA 8216 FUN_023436 0 68 0 103 0 NA NA NA NA NA NA NA 8217 FUN_014661 3876 3281 2306 3600 3970 ptg000009l:1897202-1917223 Q9NBX4 4.78e-46 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 8218 FUN_026406 318 155 114 193 94 NA NA NA NA NA NA NA 8219 FUN_026407 75 15 1 39 5 NA NA NA NA NA NA NA 8220 FUN_009209 287 221 286 107 0 NA NA NA NA NA NA NA 8221 FUN_009208 163 72 106 47 0 NA NA NA NA NA NA NA 8222 FUN_009201 0 73 96 0 13 NA NA NA NA NA NA NA 8223 FUN_009200 0 10 16 0 31 NA NA NA NA NA NA NA 8224 FUN_009203 50 125 54 81 129 ptg000004l:3902545-3906748 Q96AY4 3.41e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8225 FUN_009203 50 125 54 81 129 ptg000004l:3902545-3906748 Q96AY4 6.95e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8226 FUN_009203 50 125 54 81 129 ptg000004l:3902545-3906748 Q96AY4 2.01e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8227 FUN_009203 50 125 54 81 129 ptg000004l:3902545-3906748 Q96AY4 2.23e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8228 FUN_009203 50 125 54 81 129 ptg000004l:3902545-3906748 Q96AY4 8.89e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8229 FUN_009202 100 14 87 28 69 NA NA NA NA NA NA NA 8230 FUN_009205 43 69 30 122 33 ptg000004l:3940267-3948060 Q96AY4 2.27e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8231 FUN_009205 43 69 30 122 33 ptg000004l:3940267-3948060 Q96AY4 6.5e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8232 FUN_009205 43 69 30 122 33 ptg000004l:3940267-3948060 Q96AY4 8.45e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8233 FUN_009205 43 69 30 122 33 ptg000004l:3940267-3948060 Q96AY4 1.11e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8234 FUN_009205 43 69 30 122 33 ptg000004l:3940267-3948060 Q96AY4 3.73e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8235 FUN_009205 43 69 30 122 33 ptg000004l:3940267-3948060 Q96AY4 2.55e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8236 FUN_009204 0 52 0 0 0 NA NA NA NA NA NA NA 8237 FUN_009207 454 668 473 217 235 ptg000004l:3977032-3987141 Q96AY4 6.33e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8238 FUN_009207 454 668 473 217 235 ptg000004l:3977032-3987141 Q96AY4 2.03e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8239 FUN_009207 454 668 473 217 235 ptg000004l:3977032-3987141 Q96AY4 9.8e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8240 FUN_009207 454 668 473 217 235 ptg000004l:3977032-3987141 Q96AY4 3.2e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8241 FUN_009207 454 668 473 217 235 ptg000004l:3977032-3987141 Q96AY4 2.22e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8242 FUN_009206 23 167 41 18 0 NA NA NA NA NA NA NA 8243 FUN_014663 2947 2591 1539 2716 2930 NA NA NA NA NA NA NA 8244 FUN_026619 2989 718 1805 797 476 NA NA NA NA NA NA NA 8245 FUN_026618 1829 969 948 1034 410 ptg000020l:11583623-11591749 Q76HN1 4.03e-28 Hyaluronidase-1 (Hyal-1) (EC 3.2.1.35) (Hyaluronoglucosaminidase-1) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; cartilage development [GO:0051216]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to interleukin-1 [GO:0071347]; cellular response to pH [GO:0071467]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to UV-B [GO:0071493]; chondroitin sulfate catabolic process [GO:0030207]; embryonic skeletal joint morphogenesis [GO:0060272]; hyaluronan biosynthetic process [GO:0030213]; hyaluronan catabolic process [GO:0030214]; hyaluronan metabolic process [GO:0030212]; inflammatory response [GO:0006954]; negative regulation of cell growth [GO:0030308]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell growth [GO:0030307]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of growth [GO:0045927]; positive regulation of hyaluranon cable assembly [GO:1900106]; response to antibiotic [GO:0046677]; response to reactive oxygen species [GO:0000302]; response to virus [GO:0009615] GO:0000302; GO:0004415; GO:0005615; GO:0005737; GO:0005764; GO:0005975; GO:0006954; GO:0009615; GO:0010634; GO:0030207; GO:0030212; GO:0030213; GO:0030214; GO:0030307; GO:0030308; GO:0031410; GO:0036117; GO:0036120; GO:0044344; GO:0045766; GO:0045785; GO:0045927; GO:0046677; GO:0050501; GO:0050679; GO:0051216; GO:0052757; GO:0060272; GO:0071347; GO:0071356; GO:0071467; GO:0071493; GO:1900087; GO:1900106 8246 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 2.17e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8247 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 1.16e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8248 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 2.36e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8249 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 2.47e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8250 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 2.22e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8251 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 7.16e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8252 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 3.56e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8253 FUN_026610 13 51 39 91 28 ptg000020l:11466810-11469264 Q96AY4 4.01e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8254 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 1.01e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8255 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 8.55e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8256 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 1.03e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8257 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 4.52e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8258 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 2.51e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8259 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 1.24e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8260 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 3.87e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8261 FUN_026613 52 63 23 87 29 ptg000020l:11512956-11519076 Q80XJ3 5.51e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 8262 FUN_026617 1318 713 879 735 718 NA NA NA NA NA NA NA 8263 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 1.31e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8264 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 3.97e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8265 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 4.33e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8266 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 8.7e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8267 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 2.98e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8268 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 7.79e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8269 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 3.51e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8270 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 8.07e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8271 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 1.47e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8272 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 2.18e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8273 FUN_043041 34 65 33 58 51 ptg000047l:3317527-3325595 Q96AY4 1.37e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8274 FUN_024613 0 0 0 0 48 NA NA NA NA NA NA NA 8275 FUN_024612 0 0 0 0 14 NA NA NA NA NA NA NA 8276 FUN_024617 235 92 120 104 143 NA NA NA NA NA NA NA 8277 FUN_024616 694 441 347 652 490 NA NA NA NA NA NA NA 8278 FUN_024615 986 725 531 1361 1160 ptg000018l:9040523-9045662 Q3SWX0 1.64e-52 Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog) Bos taurus (Bovine) magnesium ion transport [GO:0015693] GO:0005769; GO:0005886; GO:0015095; GO:0015693; GO:0016020 8279 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 4.2e-81 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8280 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 3.08e-57 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8281 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 6.76e-55 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8282 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 2.5e-53 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8283 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 1.16e-41 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8284 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 1.16e-40 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8285 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 3.25e-39 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8286 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 8.95e-37 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8287 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 1.48e-35 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8288 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 5.34e-35 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8289 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 1.11e-31 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8290 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 1.15e-27 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8291 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 3.27e-26 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8292 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 3.09e-24 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8293 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 9.84e-24 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8294 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 2.04e-23 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8295 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 6.26e-23 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8296 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 6.31e-23 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8297 FUN_024614 2317 1580 1527 3144 2303 ptg000018l:8997982-9038349 B3EWZ9 4.56e-22 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 8298 FUN_024619 0 0 5 11 10 NA NA NA NA NA NA NA 8299 FUN_024618 8603 7208 4150 6373 4161 ptg000018l:9084362-9107139 Q9VJ79 3.14e-29 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 (EC 3.1.4.35) (EC 3.1.4.53) (cAMP and cGMP phosphodiesterase 11) (PDE11) Drosophila melanogaster (Fruit fly) cAMP metabolic process [GO:0046058]; cGMP metabolic process [GO:0046068]; signal transduction [GO:0007165] GO:0004114; GO:0004115; GO:0005829; GO:0007165; GO:0046058; GO:0046068; GO:0046872; GO:0047555 8300 FUN_021069 9 0 0 0 23 NA NA NA NA NA NA NA 8301 FUN_021068 54 0 75 0 214 ptg000016l:411748-413699 Q6LAF1 1.6e-49 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 8302 FUN_021067 14 0 10 3 42 NA NA NA NA NA NA NA 8303 FUN_021065 0 0 0 0 37 NA NA NA NA NA NA NA 8304 FUN_021064 0 0 5 0 6 NA NA NA NA NA NA NA 8305 FUN_022527 1076 750 470 755 462 NA NA NA NA NA NA NA 8306 FUN_017958 180 253 253 242 217 ptg000012l:2394289-2404581 Q76KP1 2.33e-27 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 8307 FUN_017958 180 253 253 242 217 ptg000012l:2394289-2404581 Q76KP1 1.06e-21 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 8308 FUN_017959 6662 4278 3149 4522 3659 NA NA NA NA NA NA NA 8309 FUN_022526 790 474 255 782 625 NA NA NA NA NA NA NA 8310 FUN_017952 617 131 304 650 240 ptg000012l:2322023-2322911 O42097 4.32e-79 Hepatocyte nuclear factor 3-beta (HNF-3-beta) (HNF-3B) (Forkhead box protein A2) (Me-HNF3B) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357]; system development [GO:0048731] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0019904; GO:0030154; GO:0048731 8311 FUN_017950 2297 1585 935 2448 2575 NA NA NA NA NA NA NA 8312 FUN_017951 443 318 185 295 215 NA NA NA NA NA NA NA 8313 FUN_017956 178 153 152 273 301 ptg000012l:2373838-2375983 Q9DBA6 4.8e-42 Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 10 kDa form; Peroxisomal leader peptide-processing protease, 49 kDa form] Mus musculus (Mouse) protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of fatty acid beta-oxidation [GO:0031998] GO:0002020; GO:0004252; GO:0005777; GO:0005782; GO:0006508; GO:0016485; GO:0031998; GO:0042802 8314 FUN_017957 938 870 528 634 976 NA NA NA NA NA NA NA 8315 FUN_017954 138 45 44 46 336 ptg000012l:2347854-2361295 A7MB54 2.79e-22 H2.0-like homeobox protein (Homeobox protein HLX1) Bos taurus (Bovine) embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; epithelial cell proliferation [GO:0050673]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; organ growth [GO:0035265]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; skeletal muscle tissue development [GO:0007519]; T-helper 1 cell differentiation [GO:0045063]; T-helper 2 cell differentiation [GO:0045064] GO:0000981; GO:0001889; GO:0005634; GO:0007519; GO:0035265; GO:0043565; GO:0045063; GO:0045064; GO:0045627; GO:0045629; GO:0046622; GO:0048484; GO:0048557; GO:0050673; GO:0050679 8316 FUN_017955 486 158 145 288 375 ptg000012l:2364934-2372584 Q6GLK6 1.68e-28 Malonate--CoA ligase ACSF3, mitochondrial (EC 6.2.1.76) (Acyl-CoA synthetase family member 3) Xenopus laevis (African clawed frog) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005739; GO:0006631; GO:0090409 8317 FUN_019499 956 514 890 1380 1035 ptg000015l:2880475-2884601 Q96AY4 7.08e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8318 FUN_019499 956 514 890 1380 1035 ptg000015l:2880475-2884601 Q96AY4 9.64e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8319 FUN_019499 956 514 890 1380 1035 ptg000015l:2880475-2884601 Q96AY4 3.43e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8320 FUN_019499 956 514 890 1380 1035 ptg000015l:2880475-2884601 Q96AY4 1.51e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8321 FUN_019499 956 514 890 1380 1035 ptg000015l:2880475-2884601 Q96AY4 1.1e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8322 FUN_019499 956 514 890 1380 1035 ptg000015l:2880475-2884601 Q96AY4 2.35e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8323 FUN_019498 0 0 0 6 0 NA NA NA NA NA NA NA 8324 FUN_022524 403 616 466 492 321 NA NA NA NA NA NA NA 8325 FUN_019495 0 0 0 24 5 NA NA NA NA NA NA NA 8326 FUN_015681 0 0 0 0 35 NA NA NA NA NA NA NA 8327 FUN_035512 200 492 135 562 64 ptg000025l:8460460-8492318 P20825 4.99e-67 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 8328 FUN_035513 8354 8812 4320 6471 6306 NA NA NA NA NA NA NA 8329 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 6.58e-34 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8330 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 2.6e-29 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8331 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 1.56e-25 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8332 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 3.02e-25 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8333 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 7.79e-25 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8334 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 1.27e-23 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8335 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 2.2e-22 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8336 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 4.48e-22 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8337 FUN_035510 0 0 52 0 0 ptg000025l:8446531-8449932 Q9R0M0 6.16e-21 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 8338 FUN_035511 1095 1054 335 459 277 NA NA NA NA NA NA NA 8339 FUN_035516 0 0 0 17 0 NA NA NA NA NA NA NA 8340 FUN_035514 229 562 124 246 361 NA NA NA NA NA NA NA 8341 FUN_035518 0 0 0 64 0 NA NA NA NA NA NA NA 8342 FUN_035519 927 1451 1293 460 769 NA NA NA NA NA NA NA 8343 FUN_030740 74 65 28 88 81 NA NA NA NA NA NA NA 8344 FUN_030741 5 13 15 29 21 NA NA NA NA NA NA NA 8345 FUN_030742 639 394 309 675 671 ptg000023l:15479782-15501171 P16423 3.61e-21 Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM (Retrovirus-related Pol polyprotein from type II retrotransposable element R2DM) [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) proteolysis [GO:0006508] GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0046872 8346 FUN_038172 13353 6100 6024 10656 8292 ptg000027l:3415043-3421220 C3YWU0 2.67e-33 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 8347 FUN_038171 541 507 387 564 495 NA NA NA NA NA NA NA 8348 FUN_038177 100 93 113 43 65 NA NA NA NA NA NA NA 8349 FUN_038176 228 73 8 3 71 NA NA NA NA NA NA NA 8350 FUN_038175 27889 14836 8594 20803 13516 ptg000027l:3449951-3456072 C3YWU0 3.46e-34 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 8351 FUN_038174 4247 3012 2850 7254 4119 ptg000027l:3434440-3444462 C3YWU0 3.71e-35 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 8352 FUN_027164 0 13 4 310 283 NA NA NA NA NA NA NA 8353 FUN_038179 573 208 369 177 439 ptg000027l:3471258-3489077 E1BZ85 3.71e-25 Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1 homolog) Gallus gallus (Chicken) meiotic cell cycle [GO:0051321]; oogenesis [GO:0048477] GO:0004540; GO:0005737; GO:0005777; GO:0048477; GO:0051321; GO:1903231; GO:1905762 8354 FUN_038178 86 14 57 38 31 NA NA NA NA NA NA NA 8355 FUN_027165 0 0 0 0 30 NA NA NA NA NA NA NA 8356 FUN_021939 1867 601 778 1480 739 NA NA NA NA NA NA NA 8357 FUN_021938 2608 2281 1849 2386 1511 NA NA NA NA NA NA NA 8358 FUN_021931 141 91 221 328 133 NA NA NA NA NA NA NA 8359 FUN_021930 8 0 225 28 67 NA NA NA NA NA NA NA 8360 FUN_021933 30 0 6 1 81 NA NA NA NA NA NA NA 8361 FUN_021932 3303 3607 1611 2877 3224 ptg000016l:3489300-3515211 Q5R4G6 1.51e-26 Cullin-1 (CUL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005886; GO:0006513; GO:0006915; GO:0008283; GO:0009887; GO:0019005; GO:0031146; GO:0031625; GO:0070936; GO:1990452 8362 FUN_021932 3303 3607 1611 2877 3224 ptg000016l:3489300-3515211 Q5R4G6 2.42e-24 Cullin-1 (CUL-1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; cell population proliferation [GO:0008283]; protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005886; GO:0006513; GO:0006915; GO:0008283; GO:0009887; GO:0019005; GO:0031146; GO:0031625; GO:0070936; GO:1990452 8363 FUN_021934 596 465 281 348 331 ptg000016l:3519283-3520040 Q6VYA3 8.01e-27 Sclerostin domain-containing protein 1 (Wnt-signaling modulator) Gallus gallus (Chicken) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0016055; GO:0030178; GO:0030514; GO:0036122 8364 FUN_021937 525 339 493 900 592 ptg000016l:3554117-3563912 Q2KIC2 7.62e-56 ETS translocation variant 1 Bos taurus (Bovine) cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0030154 8365 FUN_028848 1201 699 605 824 960 ptg000022l:4973062-4996012 Q99315 1.06e-84 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 8366 FUN_001759 6 5 1 27 40 NA NA NA NA NA NA NA 8367 FUN_001755 0 0 0 98 46 ntLink_6:15712982-15720078 C5G6D7 1.81e-26 Chondroitin sulfate ABC exolyase (EC 4.2.2.21) (Chondroitin ABC exoeliminase) (Chondroitin ABC lyase II) (Chondroitin sulfate ABC lyase II) (ChS ABC lyase II) (Chondroitinase ABC II) (cABC II) (Exochondroitinase ABC) Bacteroides thetaiotaomicron carbohydrate metabolic process [GO:0005975]; dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027] GO:0000287; GO:0005509; GO:0005576; GO:0005975; GO:0006027; GO:0030209; GO:0030246; GO:0034000; GO:0034001; GO:0042597 8368 FUN_001750 1023 711 342 628 412 NA NA NA NA NA NA NA 8369 FUN_016076 71860 104915 53795 66889 54983 NA NA NA NA NA NA NA 8370 FUN_037914 42 0 47 0 196 NA NA NA NA NA NA NA 8371 FUN_037915 4007 2632 2130 3884 3975 NA NA NA NA NA NA NA 8372 FUN_037916 1886 1677 966 2133 1984 NA NA NA NA NA NA NA 8373 FUN_037917 8005 9105 3840 5779 2436 NA NA NA NA NA NA NA 8374 FUN_037910 3441 3074 1326 2328 2194 NA NA NA NA NA NA NA 8375 FUN_037911 567 454 251 552 420 ptg000027l:399149-402149 Q9H7B4 2.72e-27 Histone-lysine N-methyltransferase SMYD3 (EC 2.1.1.354) (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; establishment of protein localization [GO:0045184]; histone lysine methylation [GO:0034968]; myotube cell development [GO:0014904]; negative regulation of protein kinase activity [GO:0006469]; nucleosome assembly [GO:0006334]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000978; GO:0000993; GO:0001162; GO:0005634; GO:0005654; GO:0005829; GO:0006334; GO:0006469; GO:0014904; GO:0018024; GO:0033138; GO:0034968; GO:0042800; GO:0045184; GO:0045944; GO:0046872; GO:0071549 8376 FUN_037912 27 0 61 0 127 NA NA NA NA NA NA NA 8377 FUN_037913 21 0 16 0 66 NA NA NA NA NA NA NA 8378 FUN_037918 2428 4220 2467 3667 2287 NA NA NA NA NA NA NA 8379 FUN_037919 790 503 297 1058 704 NA NA NA NA NA NA NA 8380 FUN_005274 65 56 76 42 39 NA NA NA NA NA NA NA 8381 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 1.9e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8382 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 1.9e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8383 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 5.23e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8384 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 7.43e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8385 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 3.61e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8386 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 8.32e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8387 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 3.96e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8388 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 2.74e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8389 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 1.58e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8390 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 2.47e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8391 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 2.87e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8392 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 4.86e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8393 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 1.66e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8394 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 9.57e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8395 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 6.56e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8396 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 3.57e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8397 FUN_005276 275 67 390 1275 1742 ntLink_8:33375139-33379317 Q96AY4 2.3e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8398 FUN_027543 0 15 0 0 0 NA NA NA NA NA NA NA 8399 FUN_005270 1261 1052 888 1904 1365 NA NA NA NA NA NA NA 8400 FUN_005271 563 220 65 78 289 NA NA NA NA NA NA NA 8401 FUN_005272 696 646 541 547 438 NA NA NA NA NA NA NA 8402 FUN_005273 38839 38026 28467 45751 40928 NA NA NA NA NA NA NA 8403 FUN_014747 110 126 164 258 98 NA NA NA NA NA NA NA 8404 FUN_007694 2087 1224 1119 1771 1865 NA NA NA NA NA NA NA 8405 FUN_007695 773 787 491 494 701 NA NA NA NA NA NA NA 8406 FUN_007696 1749 1618 680 1519 1310 ptg000002l:3329353-3337000 O14772 3.6e-34 Fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) (GDP-L-fucose diphosphorylase) (GDP-L-fucose pyrophosphorylase) Homo sapiens (Human) fucose metabolic process [GO:0006004] GO:0003824; GO:0005525; GO:0005737; GO:0005829; GO:0006004; GO:0047341 8407 FUN_007696 1749 1618 680 1519 1310 ptg000002l:3329353-3337000 O14772 1.64e-31 Fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) (GDP-L-fucose diphosphorylase) (GDP-L-fucose pyrophosphorylase) Homo sapiens (Human) fucose metabolic process [GO:0006004] GO:0003824; GO:0005525; GO:0005737; GO:0005829; GO:0006004; GO:0047341 8408 FUN_007697 890 1210 358 700 553 NA NA NA NA NA NA NA 8409 FUN_007690 1216 1230 960 1079 671 NA NA NA NA NA NA NA 8410 FUN_007692 16 159 30 19 33 NA NA NA NA NA NA NA 8411 FUN_007693 90 52 79 113 63 ptg000002l:3310649-3312180 B0BM95 4.34e-22 Actin maturation protease (EC 3.4.11.-) (Actin aminopeptidase ACTMAP) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein initiator methionine removal involved in protein maturation [GO:0035551] GO:0004177; GO:0035551 8412 FUN_016818 17 34 13 0 0 NA NA NA NA NA NA NA 8413 FUN_007698 453 168 435 251 374 NA NA NA NA NA NA NA 8414 FUN_007699 0 0 7 40 17 ptg000002l:3369642-3373954 P11617 9.93e-24 Adenosine receptor A2a Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; eating behavior [GO:0042755]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of inflammatory response [GO:0050728]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; response to amphetamine [GO:0001975]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; synaptic transmission, dopaminergic [GO:0001963] GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0007626; GO:0008289; GO:0010035; GO:0014074; GO:0019899; GO:0032230; GO:0042755; GO:0042802; GO:0046636; GO:0050728; GO:0060080; GO:0097190; GO:0098794; GO:2001235 8415 FUN_027572 94 36 102 72 54 NA NA NA NA NA NA NA 8416 FUN_027570 0 0 13 0 21 NA NA NA NA NA NA NA 8417 FUN_027579 0 18 3 47 25 NA NA NA NA NA NA NA 8418 FUN_035988 86 40 42 48 12 NA NA NA NA NA NA NA 8419 FUN_015354 0 0 0 0 22 ptg000009l:9136191-9157636 Q4R4S5 3.03e-31 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 8420 FUN_015354 0 0 0 0 22 ptg000009l:9136191-9157636 Q4R4S5 7.89e-31 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 8421 FUN_015355 20 19 30 58 8 NA NA NA NA NA NA NA 8422 FUN_033322 0 0 0 15 0 NA NA NA NA NA NA NA 8423 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 3.64e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8424 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 6.75e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8425 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 2.82e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8426 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 2.26e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8427 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 9.72e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8428 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 2.57e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8429 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 4.4e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8430 FUN_033320 217 57 144 361 202 ptg000023l:41916253-41919736 Q96AY4 5.4e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8431 FUN_015352 660 211 364 471 403 ptg000009l:9116551-9124784 Q4R4S5 3.47e-36 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 8432 FUN_004101 36 6 0 144 116 NA NA NA NA NA NA NA 8433 FUN_033329 23 26 0 5 76 NA NA NA NA NA NA NA 8434 FUN_033328 3 0 7 0 11 NA NA NA NA NA NA NA 8435 FUN_016850 389 2954 95 1326 399 NA NA NA NA NA NA NA 8436 FUN_016851 1974 1556 998 2266 1425 NA NA NA NA NA NA NA 8437 FUN_016852 0 0 26 0 45 NA NA NA NA NA NA NA 8438 FUN_016854 14 0 0 0 5 NA NA NA NA NA NA NA 8439 FUN_016858 260 185 146 182 62 NA NA NA NA NA NA NA 8440 FUN_016859 0 149 0 0 44 NA NA NA NA NA NA NA 8441 FUN_004584 1052 3358 942 11332 16721 NA NA NA NA NA NA NA 8442 FUN_004587 0 6 16 45 22 NA NA NA NA NA NA NA 8443 FUN_004581 4580 3952 1862 3453 2656 ntLink_8:24550552-24562376 Q9D0R2 2.47e-37 Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase, cytoplasmic) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1) Mus musculus (Mouse) threonyl-tRNA aminoacylation [GO:0006435] GO:0004829; GO:0005524; GO:0005737; GO:0006435; GO:0008270; GO:0042802 8444 FUN_004581 4580 3952 1862 3453 2656 ntLink_8:24550552-24562376 Q9D0R2 2.47e-37 Threonine--tRNA ligase 1, cytoplasmic (EC 6.1.1.3) (Threonine--tRNA ligase, cytoplasmic) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase 1) Mus musculus (Mouse) threonyl-tRNA aminoacylation [GO:0006435] GO:0004829; GO:0005524; GO:0005737; GO:0006435; GO:0008270; GO:0042802 8445 FUN_004583 588 560 917 946 737 NA NA NA NA NA NA NA 8446 FUN_004582 3488 4358 3639 8348 6035 NA NA NA NA NA NA NA 8447 FUN_037002 0 5 14 3 0 NA NA NA NA NA NA NA 8448 FUN_037003 208 118 81 191 167 NA NA NA NA NA NA NA 8449 FUN_037000 27 10 4 19 8 NA NA NA NA NA NA NA 8450 FUN_037001 365 209 220 174 387 NA NA NA NA NA NA NA 8451 FUN_037006 1632 1282 913 1721 1335 NA NA NA NA NA NA NA 8452 FUN_004588 143 390 145 4379 1272 NA NA NA NA NA NA NA 8453 FUN_037004 2752 2729 2995 6892 4521 NA NA NA NA NA NA NA 8454 FUN_037005 894 367 426 693 887 NA NA NA NA NA NA NA 8455 FUN_012478 50 65 15 75 97 NA NA NA NA NA NA NA 8456 FUN_043392 7688 5706 3517 6523 5752 ptg000047l:7898020-7903256 P17130 1.55e-26 Heterogeneous nuclear ribonucleoproteins A1 homolog (hnRNP A1) (Helix-destabilizing protein) (Single-strand-binding protein) (hnRNP core protein A1) Xenopus laevis (African clawed frog) NA GO:0003723; GO:0005634; GO:0005737; GO:1990904 8457 FUN_006565 239 5 123 461 48 NA NA NA NA NA NA NA 8458 FUN_006567 1076 947 453 1323 779 NA NA NA NA NA NA NA 8459 FUN_032631 147 79 46 159 143 NA NA NA NA NA NA NA 8460 FUN_006561 3528 214 1420 2411 208 NA NA NA NA NA NA NA 8461 FUN_006560 6 0 1 3 1 NA NA NA NA NA NA NA 8462 FUN_006562 769 18 301 1419 437 ptg000001l:14100543-14139304 Q7RTR2 1.34e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8463 FUN_006562 769 18 301 1419 437 ptg000001l:14100543-14139304 Q7RTR2 1.01e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8464 FUN_006562 769 18 301 1419 437 ptg000001l:14100543-14139304 Q7RTR2 7.24e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8465 FUN_006562 769 18 301 1419 437 ptg000001l:14100543-14139304 Q7RTR2 7.45e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8466 FUN_005186 1300 1270 614 1076 922 NA NA NA NA NA NA NA 8467 FUN_005187 67 0 116 0 206 NA NA NA NA NA NA NA 8468 FUN_005184 37 43 25 41 63 NA NA NA NA NA NA NA 8469 FUN_032639 58 13 7 0 54 NA NA NA NA NA NA NA 8470 FUN_005182 9059 4541 3484 6030 4360 ntLink_8:32262418-32286974 P30205 1.21e-23 Antigen WC1.1 Bos taurus (Bovine) NA GO:0005044; GO:0005576; GO:0009897 8471 FUN_005183 728 400 373 340 700 NA NA NA NA NA NA NA 8472 FUN_005180 39 9 5 144 186 NA NA NA NA NA NA NA 8473 FUN_005181 2700 1662 824 1922 1513 NA NA NA NA NA NA NA 8474 FUN_004639 459 328 165 443 487 NA NA NA NA NA NA NA 8475 FUN_033584 0 0 6 0 19 NA NA NA NA NA NA NA 8476 FUN_004637 1314 372 208 702 955 NA NA NA NA NA NA NA 8477 FUN_004635 164 528 217 337 286 ntLink_8:25185106-25199287 O95395 1.58e-60 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 8478 FUN_004634 981 936 607 1018 649 ntLink_8:25157771-25170643 O95395 2.89e-61 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 8479 FUN_004633 515 414 353 352 250 ntLink_8:25131512-25134384 O95395 6.49e-63 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (EC 2.4.1.102) (EC 2.4.1.148) (EC 2.4.1.150) (C2GnT-mucin type) (C2GnT-M) (hC2GnT-M) (Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase) (C2/4GnT) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; intestinal absorption [GO:0050892]; kidney morphogenesis [GO:0060993]; O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493]; tissue morphogenesis [GO:0048729] GO:0000139; GO:0003829; GO:0005975; GO:0006493; GO:0008109; GO:0008375; GO:0016020; GO:0016266; GO:0048729; GO:0050892; GO:0060993; GO:0070062; GO:0106325; GO:0106326 8480 FUN_012473 68 244 158 155 368 ptg000008l:9225671-9226793 Q9XTR8 9.28e-36 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 8481 FUN_008545 4564 4008 1687 3773 2643 NA NA NA NA NA NA NA 8482 FUN_006520 200 1146 372 749 1111 NA NA NA NA NA NA NA 8483 FUN_008547 38 8 10 2 12 NA NA NA NA NA NA NA 8484 FUN_034675 1841 1711 1065 582 292 NA NA NA NA NA NA NA 8485 FUN_034676 274 39 5 210 97 NA NA NA NA NA NA NA 8486 FUN_008546 1210 1553 984 1228 945 NA NA NA NA NA NA NA 8487 FUN_034670 0 0 0 49 0 NA NA NA NA NA NA NA 8488 FUN_034672 4 13 9 0 0 NA NA NA NA NA NA NA 8489 FUN_034673 4475 4020 4831 3381 2131 NA NA NA NA NA NA NA 8490 FUN_008541 314 65 104 136 88 NA NA NA NA NA NA NA 8491 FUN_034678 0 0 0 13 18 NA NA NA NA NA NA NA 8492 FUN_034679 19 41 0 0 40 NA NA NA NA NA NA NA 8493 FUN_006524 987 415 491 1488 635 NA NA NA NA NA NA NA 8494 FUN_032984 2 19 16 116 180 NA NA NA NA NA NA NA 8495 FUN_032985 2719 1489 1557 2138 2298 NA NA NA NA NA NA NA 8496 FUN_032987 1082 557 522 787 608 NA NA NA NA NA NA NA 8497 FUN_032980 2044 1370 1560 3836 2507 ptg000023l:38402010-38441925 Q92538 6.38e-58 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) Homo sapiens (Human) cell activation involved in immune response [GO:0002263]; cellular response to virus [GO:0098586]; cilium assembly [GO:0060271]; COPI coating of Golgi vesicle [GO:0048205]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; endoplasmic reticulum-Golgi intermediate compartment organization [GO:0097111]; establishment of monopolar cell polarity [GO:0061162]; Golgi disassembly [GO:0090166]; Golgi organization [GO:0007030]; Golgi to endosome transport [GO:0006895]; neutrophil chemotaxis [GO:0030593]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein localization to endoplasmic reticulum tubular network [GO:1903420]; protein localization to Golgi apparatus [GO:0034067]; protein transport [GO:0015031]; reactive oxygen species biosynthetic process [GO:1903409]; regulation of ARF protein signal transduction [GO:0032012]; regulation of mitotic cell cycle [GO:0007346]; regulation of protein localization to cell surface [GO:2000008]; retrograde transport, endosome to Golgi [GO:0042147]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0002263; GO:0005085; GO:0005547; GO:0005793; GO:0005794; GO:0005801; GO:0005802; GO:0005811; GO:0005829; GO:0006888; GO:0006890; GO:0006892; GO:0006895; GO:0007030; GO:0007346; GO:0015031; GO:0016020; GO:0030593; GO:0031252; GO:0032012; GO:0034067; GO:0042147; GO:0048205; GO:0060271; GO:0061162; GO:0070973; GO:0080025; GO:0090166; GO:0097111; GO:0098586; GO:1903409; GO:1903420; GO:2000008 8498 FUN_032981 183 153 111 271 145 NA NA NA NA NA NA NA 8499 FUN_032982 62206 107570 36405 40024 33892 ptg000023l:38451426-38453940 P21568 4.54e-27 Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (Cyclosporin A-binding protein) (Rotamase) Solanum lycopersicum (Tomato) (Lycopersicon esculentum) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0006457; GO:0016018 8500 FUN_032983 433 235 167 815 901 ptg000023l:38465787-38469018 Q96AY4 4.03e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8501 FUN_032983 433 235 167 815 901 ptg000023l:38465787-38469018 Q96AY4 2.07e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8502 FUN_032983 433 235 167 815 901 ptg000023l:38465787-38469018 Q96AY4 5.8e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8503 FUN_032983 433 235 167 815 901 ptg000023l:38465787-38469018 Q96AY4 3.47e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8504 FUN_032983 433 235 167 815 901 ptg000023l:38465787-38469018 Q96AY4 2.3e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8505 FUN_032983 433 235 167 815 901 ptg000023l:38465787-38469018 Q96AY4 7.67e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8506 FUN_008542 1125 1018 869 1050 1182 NA NA NA NA NA NA NA 8507 FUN_032988 2271 722 1837 2528 2516 ptg000023l:38532921-38555410 Q21376 9.77e-31 Putative extracellular sulfatase Sulf-1 homolog (CeSulf-1) (EC 3.1.6.-) Caenorhabditis elegans heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015] GO:0005539; GO:0005783; GO:0005795; GO:0008449; GO:0009986; GO:0015015; GO:0017095; GO:0046872 8508 FUN_032988 2271 722 1837 2528 2516 ptg000023l:38532921-38555410 Q21376 5.75e-23 Putative extracellular sulfatase Sulf-1 homolog (CeSulf-1) (EC 3.1.6.-) Caenorhabditis elegans heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015] GO:0005539; GO:0005783; GO:0005795; GO:0008449; GO:0009986; GO:0015015; GO:0017095; GO:0046872 8509 FUN_032989 47 73 62 46 72 NA NA NA NA NA NA NA 8510 FUN_016506 315 66 62 142 71 ptg000011l:4178806-4180261 Q6AX80 1.39e-86 Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) Xenopus laevis (African clawed frog) blood coagulation [GO:0007596] GO:0005886; GO:0007596; GO:0046872; GO:0047710 8511 FUN_006865 761 438 456 1383 808 NA NA NA NA NA NA NA 8512 FUN_013645 1307 1029 603 2210 705 NA NA NA NA NA NA NA 8513 FUN_006867 247 368 298 564 333 NA NA NA NA NA NA NA 8514 FUN_016502 41 20 90 46 74 NA NA NA NA NA NA NA 8515 FUN_016503 0 0 0 0 15 NA NA NA NA NA NA NA 8516 FUN_041964 2789 2103 506 580 749 NA NA NA NA NA NA NA 8517 FUN_041965 17080 15754 7461 9041 7703 NA NA NA NA NA NA NA 8518 FUN_001038 67 132 14 33 20 NA NA NA NA NA NA NA 8519 FUN_041967 1804 1722 1032 1313 1279 ptg000035l:9394728-9400144 Q03123 7.34e-24 General transcription factor IIF subunit 2 (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30) Xenopus laevis (African clawed frog) transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0003677; GO:0005674; GO:0006366; GO:0006367 8520 FUN_041960 447 499 139 250 190 NA NA NA NA NA NA NA 8521 FUN_041961 1149 903 261 332 427 NA NA NA NA NA NA NA 8522 FUN_041962 6939 8716 2591 4715 2227 NA NA NA NA NA NA NA 8523 FUN_041963 12339 9454 5226 10089 6810 ptg000035l:9341535-9347647 Q5R668 1.09e-34 Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005789; GO:0031956; GO:0047676 8524 FUN_041963 12339 9454 5226 10089 6810 ptg000035l:9341535-9347647 Q5R668 1.09e-34 Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005789; GO:0031956; GO:0047676 8525 FUN_041963 12339 9454 5226 10089 6810 ptg000035l:9341535-9347647 Q5R668 1.09e-34 Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005789; GO:0031956; GO:0047676 8526 FUN_041963 12339 9454 5226 10089 6810 ptg000035l:9341535-9347647 Q5R668 6.16e-25 Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0004467; GO:0005524; GO:0005741; GO:0005778; GO:0005789; GO:0031956; GO:0047676 8527 FUN_001032 206 49 93 98 94 ntLink_6:7395864-7396959 F1R332 6.77e-23 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 8528 FUN_001033 665 397 132 737 347 NA NA NA NA NA NA NA 8529 FUN_001030 114 124 101 426 221 NA NA NA NA NA NA NA 8530 FUN_006863 874 524 466 873 610 NA NA NA NA NA NA NA 8531 FUN_001036 630 683 496 527 609 ntLink_6:7512606-7528027 P20825 1.47e-22 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 8532 FUN_001036 630 683 496 527 609 ntLink_6:7512606-7528027 P20825 1.47e-22 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 8533 FUN_001036 630 683 496 527 609 ntLink_6:7512606-7528027 P20825 1.47e-22 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 8534 FUN_001036 630 683 496 527 609 ntLink_6:7512606-7528027 P20825 1.47e-22 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 8535 FUN_001037 0 47 30 0 23 NA NA NA NA NA NA NA 8536 FUN_001034 2042 1262 653 2847 585 NA NA NA NA NA NA NA 8537 FUN_001035 268 454 387 399 372 NA NA NA NA NA NA NA 8538 FUN_044114 84 134 122 123 380 NA NA NA NA NA NA NA 8539 FUN_011000 791 857 554 682 446 ptg000007l:5468625-5477528 A7S8T5 4.64e-21 Coiled-coil domain-containing protein 42 homolog Nematostella vectensis (Starlet sea anemone) NA NA 8540 FUN_011000 791 857 554 682 446 ptg000007l:5468625-5477528 A7S8T5 4.64e-21 Coiled-coil domain-containing protein 42 homolog Nematostella vectensis (Starlet sea anemone) NA NA 8541 FUN_011001 287 150 106 178 248 NA NA NA NA NA NA NA 8542 FUN_035985 1181 195 559 619 561 NA NA NA NA NA NA NA 8543 FUN_035984 327 141 290 113 361 NA NA NA NA NA NA NA 8544 FUN_035987 4 10 8 0 1 NA NA NA NA NA NA NA 8545 FUN_035986 118 176 236 253 164 NA NA NA NA NA NA NA 8546 FUN_035981 3368 2313 2202 3369 2974 NA NA NA NA NA NA NA 8547 FUN_035980 18 7 28 20 34 NA NA NA NA NA NA NA 8548 FUN_035983 34 0 30 0 23 NA NA NA NA NA NA NA 8549 FUN_035982 986 514 773 759 649 ptg000025l:14228277-14243922 A3KG59 3.48e-48 Xaa-Arg dipeptidase (EC 3.4.13.4) Mus musculus (Mouse) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 8550 FUN_035982 986 514 773 759 649 ptg000025l:14228277-14243922 A3KG59 7.62e-22 Xaa-Arg dipeptidase (EC 3.4.13.4) Mus musculus (Mouse) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 8551 FUN_035989 2 0 8 17 2 NA NA NA NA NA NA NA 8552 FUN_023952 2298 2462 1475 1968 1361 NA NA NA NA NA NA NA 8553 FUN_016078 203 104 186 314 313 ptg000010l:1347026-1349213 Q09470 7.16e-105 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 8554 FUN_031677 381 209 141 307 265 ptg000023l:24300542-24322049 P14381 5.61e-112 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 8555 FUN_000639 2467 1780 1344 2461 1847 ntLink_6:5251118-5264372 Q8VIJ5 3.64e-35 Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (N-acetyl-beta-glucosaminidase) Rattus norvegicus (Rat) aging [GO:0007568]; dATP metabolic process [GO:0046060]; glycoprotein metabolic process [GO:0009100]; N-acetylglucosamine metabolic process [GO:0006044]; necrotic cell death [GO:0070265]; negative regulation of cardiac muscle adaptation [GO:0010616]; negative regulation of protein glycosylation [GO:0060051]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cell killing [GO:0031343]; positive regulation of DNA metabolic process [GO:0051054]; positive regulation of glucose import [GO:0046326]; positive regulation of growth hormone secretion [GO:0060124]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of protein-containing complex disassembly [GO:0043243]; positive regulation of proteolysis [GO:0045862]; protein deglycosylation [GO:0006517]; protein targeting to membrane [GO:0006612]; response to steroid hormone [GO:0048545] GO:0004402; GO:0005634; GO:0005739; GO:0006044; GO:0006517; GO:0006612; GO:0007568; GO:0009100; GO:0010524; GO:0010616; GO:0016231; GO:0031343; GO:0032024; GO:0042802; GO:0043243; GO:0045862; GO:0046060; GO:0046326; GO:0048545; GO:0051054; GO:0051901; GO:0051928; GO:0060051; GO:0060124; GO:0070265; GO:0102166; GO:0102167; GO:0102571 8556 FUN_031675 51 64 37 56 106 ptg000023l:24287539-24293032 Q90632 8.91e-22 Monocarboxylate transporter 3 (MCT 3) (Retinal epithelial membrane protein) (Solute carrier family 16 member 8) Gallus gallus (Chicken) monocarboxylic acid transport [GO:0015718] GO:0005886; GO:0008028; GO:0015293; GO:0015718; GO:0016020; GO:0016323 8557 FUN_000633 5 2949 5 15 1399 NA NA NA NA NA NA NA 8558 FUN_000632 30022 37346 6057 18860 12085 ntLink_6:5217131-5219121 O97125 0 Heat shock protein 68 Drosophila melanogaster (Fruit fly) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; determination of adult lifespan [GO:0008340]; protein refolding [GO:0042026]; response to starvation [GO:0042594]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0008340; GO:0016192; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0042594; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 8559 FUN_000631 0 51 15 0 0 NA NA NA NA NA NA NA 8560 FUN_023956 8091 5960 4194 6754 4796 ptg000018l:544271-552731 Q58A65 1.35e-25 C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9) Mus musculus (Mouse) lysosome localization [GO:0032418]; negative regulation of dendrite extension [GO:1903860]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192] GO:0001933; GO:0005078; GO:0005737; GO:0005765; GO:0005829; GO:0008432; GO:0016192; GO:0019894; GO:0030159; GO:0030335; GO:0032418; GO:0034451; GO:0042147; GO:0042802; GO:0043410; GO:0045665; GO:0045666; GO:0048471; GO:0051146; GO:1903860 8561 FUN_023956 8091 5960 4194 6754 4796 ptg000018l:544271-552731 Q58A65 4.71e-22 C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9) Mus musculus (Mouse) lysosome localization [GO:0032418]; negative regulation of dendrite extension [GO:1903860]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192] GO:0001933; GO:0005078; GO:0005737; GO:0005765; GO:0005829; GO:0008432; GO:0016192; GO:0019894; GO:0030159; GO:0030335; GO:0032418; GO:0034451; GO:0042147; GO:0042802; GO:0043410; GO:0045665; GO:0045666; GO:0048471; GO:0051146; GO:1903860 8562 FUN_000637 49053 39568 7169 30979 17170 ntLink_6:5244470-5246789 O97125 0 Heat shock protein 68 Drosophila melanogaster (Fruit fly) cellular response to unfolded protein [GO:0034620]; chaperone cofactor-dependent protein refolding [GO:0051085]; determination of adult lifespan [GO:0008340]; protein refolding [GO:0042026]; response to starvation [GO:0042594]; vesicle-mediated transport [GO:0016192] GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0008340; GO:0016192; GO:0016887; GO:0031072; GO:0034620; GO:0042026; GO:0042594; GO:0044183; GO:0051082; GO:0051085; GO:0051787; GO:0140662 8563 FUN_000636 989 344 7 44 94 NA NA NA NA NA NA NA 8564 FUN_000635 24 0 0 0 0 NA NA NA NA NA NA NA 8565 FUN_000634 0 0 0 0 18 NA NA NA NA NA NA NA 8566 FUN_029254 184 206 163 213 427 NA NA NA NA NA NA NA 8567 FUN_029255 55 52 79 189 276 NA NA NA NA NA NA NA 8568 FUN_029256 470 270 403 412 461 NA NA NA NA NA NA NA 8569 FUN_029257 177 233 0 0 167 NA NA NA NA NA NA NA 8570 FUN_029250 808 616 542 646 568 NA NA NA NA NA NA NA 8571 FUN_029251 254 155 118 243 327 NA NA NA NA NA NA NA 8572 FUN_029252 412 448 445 390 404 ptg000022l:9610907-9613035 Q5BKT4 4.94e-70 Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-A) (Asparagine-linked glycosylation protein 10 homolog A) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487] GO:0005783; GO:0005789; GO:0006487; GO:0006488; GO:0106073 8573 FUN_029253 42 44 15 0 32 NA NA NA NA NA NA NA 8574 FUN_029258 1508 1217 703 1197 934 ptg000022l:9641296-9645572 A7RX34 2.21e-26 THO complex subunit 7 homolog Nematostella vectensis (Starlet sea anemone) mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397] GO:0000445; GO:0005737; GO:0006397; GO:0006406; GO:0016607 8575 FUN_029259 2409 1568 986 1494 1048 NA NA NA NA NA NA NA 8576 FUN_040030 240 263 189 724 193 ptg000031l:3250301-3264297 Q8C1B2 1.5e-37 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 8577 FUN_040033 9 0 10 23 10 NA NA NA NA NA NA NA 8578 FUN_040694 1620 915 915 1662 1426 NA NA NA NA NA NA NA 8579 FUN_040032 4902 5227 3472 5960 2613 ptg000031l:3324909-3327131 O18405 9.75e-40 Surfeit locus protein 4 homolog Drosophila melanogaster (Fruit fly) Golgi organization [GO:0007030]; protein transport [GO:0015031] GO:0005783; GO:0005789; GO:0005793; GO:0007030; GO:0012505; GO:0015031; GO:0045169 8580 FUN_040032 4902 5227 3472 5960 2613 ptg000031l:3324909-3327131 O18405 1.44e-37 Surfeit locus protein 4 homolog Drosophila melanogaster (Fruit fly) Golgi organization [GO:0007030]; protein transport [GO:0015031] GO:0005783; GO:0005789; GO:0005793; GO:0007030; GO:0012505; GO:0015031; GO:0045169 8581 FUN_040692 2214 1647 1105 1985 1422 NA NA NA NA NA NA NA 8582 FUN_013530 0 27 13 0 0 NA NA NA NA NA NA NA 8583 FUN_017857 7896 6602 4512 7485 3829 ptg000012l:1146142-1149099 A0A1S4F2V5 2.5e-32 NA NA NA NA 8584 FUN_017857 7896 6602 4512 7485 3829 ptg000012l:1146142-1149099 A0A1S4F2V5 3.5e-24 NA NA NA NA 8585 FUN_013532 3 2 5 5 9 NA NA NA NA NA NA NA 8586 FUN_013533 0 87 25 13 0 NA NA NA NA NA NA NA 8587 FUN_013534 16 55 22 83 148 NA NA NA NA NA NA NA 8588 FUN_013535 61 46 40 13 234 NA NA NA NA NA NA NA 8589 FUN_013536 37 43 9 5 133 NA NA NA NA NA NA NA 8590 FUN_017856 1502 915 1498 1557 1499 ptg000012l:1139716-1143136 A0A1S4F2V5 4.12e-30 NA NA NA NA 8591 FUN_017856 1502 915 1498 1557 1499 ptg000012l:1139716-1143136 A0A1S4F2V5 9.31e-23 NA NA NA NA 8592 FUN_013538 0 39 41 0 0 NA NA NA NA NA NA NA 8593 FUN_013539 26 0 14 8 0 NA NA NA NA NA NA NA 8594 FUN_010841 147 107 88 152 488 ptg000007l:3485505-3496949 Q68EI3 1.48e-37 Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) Danio rerio (Zebrafish) (Brachydanio rerio) C-terminal protein deglutamylation [GO:0035609]; chordate embryonic development [GO:0043009]; cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005634; GO:0005829; GO:0006508; GO:0008270; GO:0015631; GO:0030496; GO:0035608; GO:0035609; GO:0035610; GO:0035611; GO:0043009; GO:0051607; GO:0060271; GO:0072686 8595 FUN_010841 147 107 88 152 488 ptg000007l:3485505-3496949 Q68EI3 1.86e-35 Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) Danio rerio (Zebrafish) (Brachydanio rerio) C-terminal protein deglutamylation [GO:0035609]; chordate embryonic development [GO:0043009]; cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005634; GO:0005829; GO:0006508; GO:0008270; GO:0015631; GO:0030496; GO:0035608; GO:0035609; GO:0035610; GO:0035611; GO:0043009; GO:0051607; GO:0060271; GO:0072686 8596 FUN_010841 147 107 88 152 488 ptg000007l:3485505-3496949 Q68EI3 1.34e-30 Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) Danio rerio (Zebrafish) (Brachydanio rerio) C-terminal protein deglutamylation [GO:0035609]; chordate embryonic development [GO:0043009]; cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005634; GO:0005829; GO:0006508; GO:0008270; GO:0015631; GO:0030496; GO:0035608; GO:0035609; GO:0035610; GO:0035611; GO:0043009; GO:0051607; GO:0060271; GO:0072686 8597 FUN_010841 147 107 88 152 488 ptg000007l:3485505-3496949 Q68EI3 3.4e-25 Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) Danio rerio (Zebrafish) (Brachydanio rerio) C-terminal protein deglutamylation [GO:0035609]; chordate embryonic development [GO:0043009]; cilium assembly [GO:0060271]; defense response to virus [GO:0051607]; protein branching point deglutamylation [GO:0035611]; protein deglutamylation [GO:0035608]; protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005634; GO:0005829; GO:0006508; GO:0008270; GO:0015631; GO:0030496; GO:0035608; GO:0035609; GO:0035610; GO:0035611; GO:0043009; GO:0051607; GO:0060271; GO:0072686 8598 FUN_010840 2000 1501 875 1994 1605 ptg000007l:3437354-3475289 Q922M5 3.03e-41 Cell division cycle-associated 7-like protein (Transcription factor RAM2) Mus musculus (Mouse) positive regulation of cell population proliferation [GO:0008284]; regulation of DNA-templated transcription [GO:0006355] GO:0001650; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006355; GO:0008284 8599 FUN_010843 0 40 0 29 8 NA NA NA NA NA NA NA 8600 FUN_017854 548 329 158 541 613 ptg000012l:1120816-1125804 Q3SY77 1.55e-22 UDP-glucuronosyltransferase 3A2 (UDPGT 3A2) (EC 2.4.1.17) Homo sapiens (Human) cellular response to genistein [GO:0071412] GO:0008194; GO:0015020; GO:0043541; GO:0071412 8601 FUN_010845 0 15 0 0 0 NA NA NA NA NA NA NA 8602 FUN_043619 2892 1729 1036 2440 1794 ptg000047l:10872837-10882525 Q6DJ06 4.63e-22 LIM domain transcription factor LMO4.2 (LIM domain only protein 4.2) (LMO-4.2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; gastrulation [GO:0007369]; mesoderm development [GO:0007498]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003712; GO:0007369; GO:0007399; GO:0007498; GO:0030154; GO:0045665; GO:0045944; GO:0046872 8603 FUN_010847 14 0 0 151 13 NA NA NA NA NA NA NA 8604 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8605 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 3.53e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8606 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 8.61e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8607 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 1.32e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8608 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 2.7e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8609 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 3.26e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8610 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 1.9e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8611 FUN_010846 106 33 37 127 0 ptg000007l:3552173-3557429 Q96AY4 5.16e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8612 FUN_043616 4101 4027 5637 6610 6646 NA NA NA NA NA NA NA 8613 FUN_043617 3826 2842 2093 4225 3233 NA NA NA NA NA NA NA 8614 FUN_043610 530 529 566 780 972 NA NA NA NA NA NA NA 8615 FUN_043611 1401 555 976 1374 1274 NA NA NA NA NA NA NA 8616 FUN_043612 87 15 4 32 44 ptg000047l:10773842-10774451 P35621 2.58e-26 Protein DVR-1 Danio rerio (Zebrafish) (Brachydanio rerio) axis specification [GO:0009798]; BMP signaling pathway [GO:0030509]; convergent extension involved in gastrulation [GO:0060027]; heart looping [GO:0001947]; left/right pattern formation [GO:0060972]; neuron development [GO:0048666]; nodal signaling pathway [GO:0038092]; positive regulation of cell division [GO:0051781]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; regulation of epiboly involved in gastrulation with mouth forming second [GO:1904086]; regulation of nodal signaling pathway involved in determination of left/right asymmetry [GO:1900145]; SMAD protein signal transduction [GO:0060395] GO:0001947; GO:0005125; GO:0005615; GO:0008083; GO:0009798; GO:0010862; GO:0030509; GO:0032991; GO:0038092; GO:0048666; GO:0051781; GO:0060027; GO:0060395; GO:0060972; GO:1900145; GO:1904086 8617 FUN_043613 882 432 383 1075 378 ptg000047l:10778098-10797865 F4JTS8 1.86e-24 Protein NO VEIN (Protein EMBRYO DEFECTIVE 2597) Arabidopsis thaliana (Mouse-ear cress) auxin polar transport [GO:0009926]; cell fate specification [GO:0001708]; embryo development ending in seed dormancy [GO:0009793]; leaf vascular tissue pattern formation [GO:0010305]; root development [GO:0048364]; stem cell population maintenance [GO:0019827] GO:0001708; GO:0005634; GO:0009793; GO:0009926; GO:0010305; GO:0019827; GO:0048364 8618 FUN_017851 9067 11906 7917 6271 3382 NA NA NA NA NA NA NA 8619 FUN_008930 143 77 48 78 83 ptg000004l:603398-607504 Q9H5Z1 0 Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35) Homo sapiens (Human) in utero embryonic development [GO:0001701]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0001701; GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0071013 8620 FUN_008931 2721 1880 1442 2130 1509 ptg000004l:607798-613967 Q8BSY0 4.01e-32 Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane transport [GO:0070588]; cell population proliferation [GO:0008283]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell population proliferation [GO:0008285]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteolysis [GO:0045862]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]; roof of mouth development [GO:0060021] GO:0005509; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0007389; GO:0008283; GO:0008285; GO:0010524; GO:0016020; GO:0031585; GO:0031647; GO:0032237; GO:0032541; GO:0033017; GO:0033198; GO:0035108; GO:0042264; GO:0045862; GO:0045893; GO:0051480; GO:0055074; GO:0060021; GO:0060325; GO:0062101; GO:0070588; GO:0071277; GO:0090316; GO:0097202; GO:1901879 8621 FUN_008931 2721 1880 1442 2130 1509 ptg000004l:607798-613967 Q8BSY0 3.66e-22 Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of store-operated calcium channel activity [GO:0032237]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane transport [GO:0070588]; cell population proliferation [GO:0008283]; cellular response to calcium ion [GO:0071277]; face morphogenesis [GO:0060325]; limb morphogenesis [GO:0035108]; negative regulation of cell population proliferation [GO:0008285]; pattern specification process [GO:0007389]; peptidyl-aspartic acid hydroxylation [GO:0042264]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of intracellular protein transport [GO:0090316]; positive regulation of proteolysis [GO:0045862]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of protein depolymerization [GO:1901879]; regulation of protein stability [GO:0031647]; response to ATP [GO:0033198]; roof of mouth development [GO:0060021] GO:0005509; GO:0005737; GO:0005783; GO:0005789; GO:0005886; GO:0007389; GO:0008283; GO:0008285; GO:0010524; GO:0016020; GO:0031585; GO:0031647; GO:0032237; GO:0032541; GO:0033017; GO:0033198; GO:0035108; GO:0042264; GO:0045862; GO:0045893; GO:0051480; GO:0055074; GO:0060021; GO:0060325; GO:0062101; GO:0070588; GO:0071277; GO:0090316; GO:0097202; GO:1901879 8622 FUN_008932 112 108 44 172 206 NA NA NA NA NA NA NA 8623 FUN_008933 1358 760 434 1117 1011 ptg000004l:615391-617211 Q5ZKD9 1.52e-26 Kelch-like protein 20 Gallus gallus (Chicken) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 8624 FUN_008933 1358 760 434 1117 1011 ptg000004l:615391-617211 Q5ZKD9 2.33e-23 Kelch-like protein 20 Gallus gallus (Chicken) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 8625 FUN_008933 1358 760 434 1117 1011 ptg000004l:615391-617211 Q5ZKD9 7.95e-21 Kelch-like protein 20 Gallus gallus (Chicken) Golgi to endosome transport [GO:0006895]; negative regulation of apoptotic process [GO:0043066]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K33-linked ubiquitination [GO:1990390]; protein transport [GO:0015031]; protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0005802; GO:0005829; GO:0006895; GO:0015031; GO:0016567; GO:0016605; GO:0019964; GO:0031463; GO:0043066; GO:0043161; GO:0048471; GO:1990390 8626 FUN_008934 6998 8406 3916 9244 6564 ptg000004l:622874-629747 A5D7I4 5.2e-82 Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog) Bos taurus (Bovine) antigen processing and presentation [GO:0019882]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; bone resorption [GO:0045453]; canonical Wnt signaling pathway [GO:0060070]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cell adhesion mediated by integrin [GO:0033627]; cell fate commitment [GO:0045165]; cellular response to virus [GO:0098586]; chondrocyte hypertrophy [GO:0003415]; chondrocyte proliferation [GO:0035988]; chondroitin sulfate metabolic process [GO:0030204]; collagen fibril organization [GO:0030199]; cranial skeletal system development [GO:1904888]; dendrite self-avoidance [GO:0070593]; dendritic cell migration [GO:0036336]; developmental growth involved in morphogenesis [GO:0060560]; embryonic skeletal joint development [GO:0072498]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; endoderm development [GO:0007492]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; fear response [GO:0042596]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fluid transport [GO:0042044]; gastrulation [GO:0007369]; gene expression [GO:0010467]; glandular epithelial cell differentiation [GO:0002067]; glomerular basement membrane development [GO:0032836]; hair follicle morphogenesis [GO:0031069]; heart contraction [GO:0060047]; heart field specification [GO:0003128]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell homeostasis [GO:0061484]; hematopoietic stem cell migration to bone marrow [GO:0097241]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; hypersensitivity [GO:0002524]; leukocyte tethering or rolling [GO:0050901]; limb joint morphogenesis [GO:0036022]; lymphocyte adhesion to endothelial cell of high endothelial venule [GO:0036339]; lymphocyte migration into lymphoid organs [GO:0097021]; mesenchymal cell differentiation involved in bone development [GO:1901706]; mesoderm development [GO:0007498]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; multicellular organismal water homeostasis [GO:0050891]; neural crest cell differentiation [GO:0014033]; olfactory bulb development [GO:0021772]; optic nerve development [GO:0021554]; ossification involved in bone maturation [GO:0043931]; perichondral bone morphogenesis [GO:0061974]; podocyte differentiation [GO:0072112]; protein catabolic process [GO:0030163]; protein glycosylation [GO:0006486]; protein-containing complex assembly [GO:0065003]; regulation of blood pressure [GO:0008217]; response to heparin [GO:0071503]; response to leukemia inhibitory factor [GO:1990823]; response to light intensity [GO:0009642]; sebaceous gland development [GO:0048733]; smoothened signaling pathway involved in lung development [GO:0060506]; social behavior [GO:0035176]; sodium ion homeostasis [GO:0055078]; stem cell division [GO:0017145]; stomach development [GO:0062094]; sulfation [GO:0051923]; sweat gland development [GO:0060792]; synaptic transmission, glutamatergic [GO:0035249]; tight junction organization [GO:0120193]; TNFSF11-mediated signaling pathway [GO:0071847]; vacuole organization [GO:0007033]; vasodilation [GO:0042311]; vocalization behavior [GO:0071625]; wound healing [GO:0042060] GO:0000139; GO:0001958; GO:0001974; GO:0002067; GO:0002524; GO:0003128; GO:0003415; GO:0003416; GO:0005789; GO:0005794; GO:0006486; GO:0007033; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0008217; GO:0008375; GO:0008543; GO:0009642; GO:0010467; GO:0014033; GO:0015014; GO:0015020; GO:0016757; GO:0017145; GO:0019882; GO:0021554; GO:0021772; GO:0030163; GO:0030199; GO:0030204; GO:0030210; GO:0030509; GO:0031069; GO:0032836; GO:0033627; GO:0035176; GO:0035249; GO:0035264; GO:0035988; GO:0036022; GO:0036336; GO:0036339; GO:0042044; GO:0042060; GO:0042311; GO:0042596; GO:0042803; GO:0043931; GO:0045165; GO:0045202; GO:0045453; GO:0046872; GO:0046982; GO:0048733; GO:0050508; GO:0050509; GO:0050891; GO:0050901; GO:0051923; GO:0055078; GO:0060047; GO:0060070; GO:0060218; GO:0060351; GO:0060441; GO:0060506; GO:0060560; GO:0060792; GO:0061484; GO:0061744; GO:0061974; GO:0062094; GO:0065003; GO:0070593; GO:0071503; GO:0071625; GO:0071711; GO:0071847; GO:0072112; GO:0072498; GO:0097021; GO:0097241; GO:0098586; GO:0120193; GO:1901706; GO:1904888; GO:1990823 8627 FUN_008934 6998 8406 3916 9244 6564 ptg000004l:622874-629747 A5D7I4 2.15e-43 Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog) Bos taurus (Bovine) antigen processing and presentation [GO:0019882]; axon guidance [GO:0007411]; basement membrane organization [GO:0071711]; blood vessel remodeling [GO:0001974]; BMP signaling pathway [GO:0030509]; bone resorption [GO:0045453]; canonical Wnt signaling pathway [GO:0060070]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cell adhesion mediated by integrin [GO:0033627]; cell fate commitment [GO:0045165]; cellular response to virus [GO:0098586]; chondrocyte hypertrophy [GO:0003415]; chondrocyte proliferation [GO:0035988]; chondroitin sulfate metabolic process [GO:0030204]; collagen fibril organization [GO:0030199]; cranial skeletal system development [GO:1904888]; dendrite self-avoidance [GO:0070593]; dendritic cell migration [GO:0036336]; developmental growth involved in morphogenesis [GO:0060560]; embryonic skeletal joint development [GO:0072498]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; endoderm development [GO:0007492]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; fear response [GO:0042596]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fluid transport [GO:0042044]; gastrulation [GO:0007369]; gene expression [GO:0010467]; glandular epithelial cell differentiation [GO:0002067]; glomerular basement membrane development [GO:0032836]; hair follicle morphogenesis [GO:0031069]; heart contraction [GO:0060047]; heart field specification [GO:0003128]; hematopoietic stem cell differentiation [GO:0060218]; hematopoietic stem cell homeostasis [GO:0061484]; hematopoietic stem cell migration to bone marrow [GO:0097241]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; hypersensitivity [GO:0002524]; leukocyte tethering or rolling [GO:0050901]; limb joint morphogenesis [GO:0036022]; lymphocyte adhesion to endothelial cell of high endothelial venule [GO:0036339]; lymphocyte migration into lymphoid organs [GO:0097021]; mesenchymal cell differentiation involved in bone development [GO:1901706]; mesoderm development [GO:0007498]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; multicellular organismal water homeostasis [GO:0050891]; neural crest cell differentiation [GO:0014033]; olfactory bulb development [GO:0021772]; optic nerve development [GO:0021554]; ossification involved in bone maturation [GO:0043931]; perichondral bone morphogenesis [GO:0061974]; podocyte differentiation [GO:0072112]; protein catabolic process [GO:0030163]; protein glycosylation [GO:0006486]; protein-containing complex assembly [GO:0065003]; regulation of blood pressure [GO:0008217]; response to heparin [GO:0071503]; response to leukemia inhibitory factor [GO:1990823]; response to light intensity [GO:0009642]; sebaceous gland development [GO:0048733]; smoothened signaling pathway involved in lung development [GO:0060506]; social behavior [GO:0035176]; sodium ion homeostasis [GO:0055078]; stem cell division [GO:0017145]; stomach development [GO:0062094]; sulfation [GO:0051923]; sweat gland development [GO:0060792]; synaptic transmission, glutamatergic [GO:0035249]; tight junction organization [GO:0120193]; TNFSF11-mediated signaling pathway [GO:0071847]; vacuole organization [GO:0007033]; vasodilation [GO:0042311]; vocalization behavior [GO:0071625]; wound healing [GO:0042060] GO:0000139; GO:0001958; GO:0001974; GO:0002067; GO:0002524; GO:0003128; GO:0003415; GO:0003416; GO:0005789; GO:0005794; GO:0006486; GO:0007033; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0008217; GO:0008375; GO:0008543; GO:0009642; GO:0010467; GO:0014033; GO:0015014; GO:0015020; GO:0016757; GO:0017145; GO:0019882; GO:0021554; GO:0021772; GO:0030163; GO:0030199; GO:0030204; GO:0030210; GO:0030509; GO:0031069; GO:0032836; GO:0033627; GO:0035176; GO:0035249; GO:0035264; GO:0035988; GO:0036022; GO:0036336; GO:0036339; GO:0042044; GO:0042060; GO:0042311; GO:0042596; GO:0042803; GO:0043931; GO:0045165; GO:0045202; GO:0045453; GO:0046872; GO:0046982; GO:0048733; GO:0050508; GO:0050509; GO:0050891; GO:0050901; GO:0051923; GO:0055078; GO:0060047; GO:0060070; GO:0060218; GO:0060351; GO:0060441; GO:0060506; GO:0060560; GO:0060792; GO:0061484; GO:0061744; GO:0061974; GO:0062094; GO:0065003; GO:0070593; GO:0071503; GO:0071625; GO:0071711; GO:0071847; GO:0072112; GO:0072498; GO:0097021; GO:0097241; GO:0098586; GO:0120193; GO:1901706; GO:1904888; GO:1990823 8628 FUN_008935 1736 830 748 1685 1490 NA NA NA NA NA NA NA 8629 FUN_008936 448 154 159 292 320 NA NA NA NA NA NA NA 8630 FUN_008937 833 507 380 453 204 NA NA NA NA NA NA NA 8631 FUN_008938 1290 814 313 700 656 NA NA NA NA NA NA NA 8632 FUN_008939 482 254 77 331 230 ptg000004l:666948-667812 Q09081 9.91e-46 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 8633 FUN_013398 11656 7866 2302 5344 4228 NA NA NA NA NA NA NA 8634 FUN_023648 1204 773 564 950 1494 NA NA NA NA NA NA NA 8635 FUN_028618 31 20 17 35 0 ptg000022l:1568834-1576830 Q96AY4 7.98e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8636 FUN_028618 31 20 17 35 0 ptg000022l:1568834-1576830 Q96AY4 9.6e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8637 FUN_028617 35 14 0 18 0 ptg000022l:1556095-1560472 Q96AY4 1.02e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8638 FUN_028617 35 14 0 18 0 ptg000022l:1556095-1560472 Q96AY4 4.47e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8639 FUN_028617 35 14 0 18 0 ptg000022l:1556095-1560472 Q96AY4 2.65e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 8640 FUN_023644 802 685 531 686 535 NA NA NA NA NA NA NA 8641 FUN_023646 269 498 269 141 83 NA NA NA NA NA NA NA 8642 FUN_013392 7506 7861 5552 4486 3296 NA NA NA NA NA NA NA 8643 FUN_013393 2237 1278 1637 2582 1257 ptg000008l:22006955-22037572 Q96DM1 1.67e-37 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 8644 FUN_041107 6 0 0 1 0 NA NA NA NA NA NA NA 8645 FUN_041104 0 0 0 0 6 NA NA NA NA NA NA NA 8646 FUN_038325 286 32 142 303 277 NA NA NA NA NA NA NA 8647 FUN_041109 2 0 0 0 37 ptg000034l:719157-720656 Q6LAF1 3.6e-40 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 8648 FUN_002099 15 2 40 23 38 NA NA NA NA NA NA NA 8649 FUN_002098 0 0 0 15 27 NA NA NA NA NA NA NA 8650 FUN_002091 518 630 169 1200 616 NA NA NA NA NA NA NA 8651 FUN_002090 0 0 8 0 0 NA NA NA NA NA NA NA 8652 FUN_002093 1758 1385 1495 3075 3314 NA NA NA NA NA NA NA 8653 FUN_002092 197 316 181 178 201 ntLink_6:19607616-19619698 H3BCW1 5.02e-30 ADP-ribosylhydrolase ARH3 (ADP-ribose glycohydrolase ARH3) (LchARH3) (ADP-ribosylhydrolase 3) (O-acetyl-ADP-ribose deacetylase ARH3) (EC 3.5.1.-) (Poly(ADP-ribose) glycohydrolase ARH3) (EC 3.2.1.143) ([Protein ADP-ribosylarginine] hydrolase-like protein 2) ([Protein ADP-ribosylserine] hydrolase) (EC 3.2.2.-) Latimeria chalumnae (Coelacanth) DNA repair [GO:0006281]; negative regulation of necroptotic process [GO:0060546]; peptidyl-serine ADP-deribosylation [GO:0140290] GO:0000287; GO:0004649; GO:0005634; GO:0005694; GO:0005759; GO:0006281; GO:0060546; GO:0140290 8654 FUN_002095 0 0 2 15 11 NA NA NA NA NA NA NA 8655 FUN_002094 27 6 51 4 241 NA NA NA NA NA NA NA 8656 FUN_002096 0 7 15 0 98 NA NA NA NA NA NA NA 8657 FUN_011820 258 3 101 140 122 NA NA NA NA NA NA NA 8658 FUN_011821 39 8 43 32 32 ptg000008l:1827496-1831777 Q7RTR2 4.39e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8659 FUN_011826 280 0 128 147 140 NA NA NA NA NA NA NA 8660 FUN_011827 59 18 78 50 44 ptg000008l:1859688-1863953 Q7RTR2 4.36e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8661 FUN_028153 415 335 73 495 163 NA NA NA NA NA NA NA 8662 FUN_025720 25 0 0 7 8 NA NA NA NA NA NA NA 8663 FUN_025722 45 65 105 64 394 NA NA NA NA NA NA NA 8664 FUN_022111 1569 969 743 1568 925 NA NA NA NA NA NA NA 8665 FUN_025724 80061 42011 33465 65316 34616 NA NA NA NA NA NA NA 8666 FUN_025725 4031 3848 2658 3493 3051 NA NA NA NA NA NA NA 8667 FUN_025727 469 256 425 658 593 NA NA NA NA NA NA NA 8668 FUN_025728 1419 989 1124 2455 1106 NA NA NA NA NA NA NA 8669 FUN_025729 172 197 84 278 83 NA NA NA NA NA NA NA 8670 FUN_024451 1263 1093 595 903 438 NA NA NA NA NA NA NA 8671 FUN_008067 2161 884 410 983 755 NA NA NA NA NA NA NA 8672 FUN_008064 0 3 0 12 0 NA NA NA NA NA NA NA 8673 FUN_008065 1128 994 784 1361 754 ptg000002l:7621689-7625076 Q75WE7 2.59e-81 von Willebrand factor A domain-containing protein 5A (Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog) (Mast cell surface antigen 1) (Masa-1) Rattus norvegicus (Rat) NA NA 8674 FUN_008062 47 59 33 390 0 NA NA NA NA NA NA NA 8675 FUN_024454 7636 5415 3056 5312 3464 NA NA NA NA NA NA NA 8676 FUN_024457 1264 1059 944 2139 1531 ptg000018l:6596523-6601046 Q9H8H3 8.22e-26 Putative methyltransferase-like protein 7A (EC 2.1.1.-) (Protein AAM-B) Homo sapiens (Human) methylation [GO:0032259] GO:0005576; GO:0005783; GO:0005811; GO:0008168; GO:0016020; GO:0032259; GO:1904724 8677 FUN_008061 7485 11685 5744 6538 3954 NA NA NA NA NA NA NA 8678 FUN_024459 16 44 51 90 110 ptg000018l:6615854-6617977 P30437 4.1e-81 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0042448; GO:0047442 8679 FUN_024458 831 2141 361 1035 709 NA NA NA NA NA NA NA 8680 FUN_008068 0 18 14 12 6 NA NA NA NA NA NA NA 8681 FUN_028159 833 595 450 629 594 NA NA NA NA NA NA NA 8682 FUN_044057 5 5 12 4 110 NA NA NA NA NA NA NA 8683 FUN_014376 48 7 7 9 19 NA NA NA NA NA NA NA 8684 FUN_014375 16 4 12 4 17 NA NA NA NA NA NA NA 8685 FUN_014374 2 37 8 14 31 NA NA NA NA NA NA NA 8686 FUN_014373 0 0 2 0 12 NA NA NA NA NA NA NA 8687 FUN_014371 37 15 2 8 3 NA NA NA NA NA NA NA 8688 FUN_014370 16 12 4 10 17 NA NA NA NA NA NA NA 8689 FUN_044059 6 14 11 15 39 NA NA NA NA NA NA NA 8690 FUN_044058 62 123 118 117 372 NA NA NA NA NA NA NA 8691 FUN_006677 196 0 0 485 4 NA NA NA NA NA NA NA 8692 FUN_014953 118 214 66 185 136 NA NA NA NA NA NA NA 8693 FUN_014952 2445 1044 1122 1874 1502 NA NA NA NA NA NA NA 8694 FUN_014951 2674 1697 1203 1455 1567 NA NA NA NA NA NA NA 8695 FUN_014950 582 869 340 417 234 NA NA NA NA NA NA NA 8696 FUN_014957 491 533 230 871 351 ptg000009l:4756702-4763243 Q9Y5Z4 8.88e-25 Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005576; GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035578; GO:0035794; GO:0070062 8697 FUN_014956 280 151 139 300 229 ptg000009l:4733834-4747251 Q2HH38 9.85e-48 Histone H2B Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 8698 FUN_014955 4682 4101 2352 2638 1529 NA NA NA NA NA NA NA 8699 FUN_014954 2486 2336 1345 1305 816 NA NA NA NA NA NA NA 8700 FUN_014959 0 8 0 6 0 NA NA NA NA NA NA NA 8701 FUN_014958 0 0 0 0 17 NA NA NA NA NA NA NA 8702 FUN_038771 167 171 57 97 87 NA NA NA NA NA NA NA 8703 FUN_038770 501 196 190 294 243 ptg000027l:11158545-11160905 B5X2B8 1.16e-44 GTPase Era, mitochondrial (ERA-like protein 1) Salmo salar (Atlantic salmon) ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0005525; GO:0005743; GO:0005759; GO:0019843; GO:0043024 8704 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 7.03e-87 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8705 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 7.83e-87 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8706 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 1.7e-86 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8707 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 1.04e-66 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8708 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 7.12e-66 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8709 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 1.04e-65 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8710 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 2.22e-32 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8711 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 4.99e-32 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8712 FUN_038773 6 25 10 78 27 ptg000027l:11194150-11264000 O15439 5.77e-31 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8713 FUN_038772 68 200 137 154 110 ptg000027l:11171945-11182759 O15439 9.22e-88 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8714 FUN_038772 68 200 137 154 110 ptg000027l:11171945-11182759 O15439 1.83e-67 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8715 FUN_038772 68 200 137 154 110 ptg000027l:11171945-11182759 O15439 3.05e-31 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8716 FUN_038775 0 0 0 0 23 ptg000027l:11281861-11282881 E9Q236 1.92e-30 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 8717 FUN_038774 7 16 5 20 15 ptg000027l:11274828-11275287 F1M3J4 4.94e-52 ATP-binding cassette subfamily C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Rattus norvegicus (Rat) bile acid and bile salt transport [GO:0015721]; bile acid signaling pathway [GO:0038183]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410]; transmembrane transport [GO:0055085]; urate transport [GO:0015747] GO:0001409; GO:0005524; GO:0005886; GO:0008559; GO:0009410; GO:0010033; GO:0010243; GO:0014070; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0038183; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115 8718 FUN_038777 0 0 54 0 24 ptg000027l:11296199-11301376 O15439 7.76e-89 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 8719 FUN_038776 99 91 37 82 68 ptg000027l:11283316-11288671 E9Q236 4.27e-70 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 8720 FUN_038779 4 0 172 109 194 NA NA NA NA NA NA NA 8721 FUN_015024 2140 2275 1140 3046 2622 NA NA NA NA NA NA NA 8722 FUN_015025 2656 2003 982 1816 1328 ptg000009l:5392788-5400291 Q9Y295 1.75e-31 Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic spindle assembly [GO:1901673] GO:0002181; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0008017; GO:0016020; GO:0016604; GO:0030955; GO:0031116; GO:0042802; GO:1901673 8723 FUN_015025 2656 2003 982 1816 1328 ptg000009l:5392788-5400291 Q9Y295 5.17e-24 Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) Homo sapiens (Human) cytoplasmic translation [GO:0002181]; positive regulation of microtubule polymerization [GO:0031116]; regulation of mitotic spindle assembly [GO:1901673] GO:0002181; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0008017; GO:0016020; GO:0016604; GO:0030955; GO:0031116; GO:0042802; GO:1901673 8724 FUN_015026 2187 1422 951 2118 1283 ptg000009l:5402682-5408796 A0JP43 2.11e-31 EF-hand calcium-binding domain-containing protein 5 Mus musculus (Mouse) NA GO:0005509 8725 FUN_015027 922 571 351 717 274 NA NA NA NA NA NA NA 8726 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.25e-92 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8727 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.25e-92 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8728 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 8.77e-88 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8729 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 2.96e-61 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8730 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 3.52e-45 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8731 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 4.19e-44 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8732 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 4.44e-44 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8733 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.15e-42 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8734 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 7.1e-41 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8735 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.07e-38 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8736 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 5.76e-38 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8737 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 4.88e-32 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8738 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.71e-28 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8739 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.84e-28 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8740 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 7.19e-27 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8741 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 9.16e-27 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8742 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 2.15e-26 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8743 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 3.99e-26 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8744 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.34e-24 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8745 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 6.95e-24 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8746 FUN_015021 5163 3360 2576 5010 4862 ptg000009l:5282981-5333096 Q8IVF4 1.4e-23 Dynein axonemal heavy chain 10 (Axonemal beta dynein heavy chain 10) (Ciliary dynein heavy chain 10) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959; GO:0097729 8747 FUN_015022 349 204 237 550 528 NA NA NA NA NA NA NA 8748 FUN_015023 600 305 461 366 945 NA NA NA NA NA NA NA 8749 FUN_015028 529 125 71 442 222 NA NA NA NA NA NA NA 8750 FUN_015029 943 496 596 1036 1253 NA NA NA NA NA NA NA 8751 FUN_024189 0 19 19 22 38 NA NA NA NA NA NA NA 8752 FUN_024188 1606 891 1303 1790 3101 NA NA NA NA NA NA NA 8753 FUN_024183 0 0 6 34 0 NA NA NA NA NA NA NA 8754 FUN_024182 2 0 5 2 72 NA NA NA NA NA NA NA 8755 FUN_024181 4 0 0 3 7 NA NA NA NA NA NA NA 8756 FUN_024187 4385 4412 3450 6980 5503 ptg000018l:3178349-3186610 P55931 3.26e-97 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) Sus scrofa (Pig) electron transport chain [GO:0022900]; response to oxidative stress [GO:0006979] GO:0004174; GO:0005739; GO:0005743; GO:0006979; GO:0009055; GO:0016020; GO:0016491; GO:0022900; GO:0046872; GO:0048039; GO:0050660; GO:0051536; GO:0051539 8757 FUN_024187 4385 4412 3450 6980 5503 ptg000018l:3178349-3186610 P55931 4.27e-22 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) Sus scrofa (Pig) electron transport chain [GO:0022900]; response to oxidative stress [GO:0006979] GO:0004174; GO:0005739; GO:0005743; GO:0006979; GO:0009055; GO:0016020; GO:0016491; GO:0022900; GO:0046872; GO:0048039; GO:0050660; GO:0051536; GO:0051539 8758 FUN_024187 4385 4412 3450 6980 5503 ptg000018l:3178349-3186610 P55931 4.27e-22 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETF-QO) (ETF-ubiquinone oxidoreductase) (EC 1.5.5.1) (Electron-transferring-flavoprotein dehydrogenase) (ETF dehydrogenase) Sus scrofa (Pig) electron transport chain [GO:0022900]; response to oxidative stress [GO:0006979] GO:0004174; GO:0005739; GO:0005743; GO:0006979; GO:0009055; GO:0016020; GO:0016491; GO:0022900; GO:0046872; GO:0048039; GO:0050660; GO:0051536; GO:0051539 8759 FUN_024186 896 286 521 603 1124 ptg000018l:3166095-3177474 Q3LSS0 2.27e-41 CWF19-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0071014 8760 FUN_024184 0 0 0 115 0 NA NA NA NA NA NA NA 8761 FUN_006532 13 0 0 13 0 NA NA NA NA NA NA NA 8762 FUN_029994 35 80 46 25 255 NA NA NA NA NA NA NA 8763 FUN_020601 138 152 70 114 295 NA NA NA NA NA NA NA 8764 FUN_020602 230 95 58 126 121 NA NA NA NA NA NA NA 8765 FUN_020603 0 0 0 23 10 NA NA NA NA NA NA NA 8766 FUN_020605 0 0 0 0 11 NA NA NA NA NA NA NA 8767 FUN_006530 0 0 7 29 4 NA NA NA NA NA NA NA 8768 FUN_040073 225 201 181 263 82 NA NA NA NA NA NA NA 8769 FUN_010639 2552 1734 1363 2137 2063 ptg000007l:1092947-1097408 Q92968 4.9e-35 Peroxisomal membrane protein PEX13 (Peroxin-13) Homo sapiens (Human) cerebral cortex cell migration [GO:0021795]; fatty acid alpha-oxidation [GO:0001561]; locomotory behavior [GO:0007626]; microtubule-based peroxisome localization [GO:0060152]; neuron migration [GO:0001764]; protein import into peroxisome matrix, docking [GO:0016560]; suckling behavior [GO:0001967] GO:0001561; GO:0001764; GO:0001967; GO:0005777; GO:0005778; GO:0005829; GO:0007626; GO:0008320; GO:0016020; GO:0016560; GO:0021795; GO:0060152; GO:1990429 8770 FUN_022938 1213 1209 786 894 509 NA NA NA NA NA NA NA 8771 FUN_022939 28164 28905 5640 20641 4383 NA NA NA NA NA NA NA 8772 FUN_022934 63 0 10 26 40 NA NA NA NA NA NA NA 8773 FUN_022935 0 0 0 18 22 NA NA NA NA NA NA NA 8774 FUN_022936 751 593 184 642 331 NA NA NA NA NA NA NA 8775 FUN_022937 1720 1173 610 1016 696 ptg000017l:1727524-1733884 P42168 2.1e-30 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Caenorhabditis elegans negative regulation of canonical Wnt signaling pathway [GO:0090090]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, regulating spindle positioning [GO:0060069] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0007165; GO:0016055; GO:0018105; GO:0032436; GO:0060069; GO:0090090; GO:0106310 8776 FUN_022937 1720 1173 610 1016 696 ptg000017l:1727524-1733884 P42168 3.84e-24 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Caenorhabditis elegans negative regulation of canonical Wnt signaling pathway [GO:0090090]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, regulating spindle positioning [GO:0060069] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0007165; GO:0016055; GO:0018105; GO:0032436; GO:0060069; GO:0090090; GO:0106310 8777 FUN_022930 316 224 97 230 176 NA NA NA NA NA NA NA 8778 FUN_022931 58 114 60 55 209 NA NA NA NA NA NA NA 8779 FUN_022932 15 56 0 56 16 ptg000017l:1678545-1680833 Q32LB9 1.19e-32 Nitric oxide-associated protein 1 Bos taurus (Bovine) apoptotic process [GO:0006915]; mitochondrial translation [GO:0032543]; regulation of cell death [GO:0010941]; regulation of cellular respiration [GO:0043457] GO:0005525; GO:0005743; GO:0006915; GO:0010941; GO:0032543; GO:0043457 8780 FUN_022933 582 196 148 1264 1832 NA NA NA NA NA NA NA 8781 FUN_027372 1 3 8 0 0 NA NA NA NA NA NA NA 8782 FUN_027375 0 0 12 0 0 NA NA NA NA NA NA NA 8783 FUN_027377 38 55 33 229 0 NA NA NA NA NA NA NA 8784 FUN_027379 3 9 4 2 0 NA NA NA NA NA NA NA 8785 FUN_006534 88 0 0 148 0 NA NA NA NA NA NA NA 8786 FUN_039281 0 1 0 10 0 NA NA NA NA NA NA NA 8787 FUN_035552 6445 6179 3267 5073 3395 NA NA NA NA NA NA NA 8788 FUN_004076 0 22 267 0 336 NA NA NA NA NA NA NA 8789 FUN_043649 0 17 64 0 21 NA NA NA NA NA NA NA 8790 FUN_043648 43 23 31 11 36 NA NA NA NA NA NA NA 8791 FUN_010838 531 467 305 340 403 ptg000007l:3425135-3433967 Q0P5E2 6.55e-30 GPN-loop GTPase 3 (ATP-binding domain 1 family member C) Bos taurus (Bovine) NA GO:0003924; GO:0005525; GO:0032991 8792 FUN_002535 1635 1599 390 1699 845 NA NA NA NA NA NA NA 8793 FUN_010839 375 365 229 110 131 NA NA NA NA NA NA NA 8794 FUN_002532 13 0 9 0 0 NA NA NA NA NA NA NA 8795 FUN_002533 39 0 11 0 0 NA NA NA NA NA NA NA 8796 FUN_043644 54 62 3 105 42 NA NA NA NA NA NA NA 8797 FUN_002531 2179 229 298 3391 560 NA NA NA NA NA NA NA 8798 FUN_004039 2932 2052 1016 1651 1048 NA NA NA NA NA NA NA 8799 FUN_004038 4616 3656 1950 2860 1640 ntLink_8:18514184-18525205 Q32Q06 6.74e-22 AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin) Rattus norvegicus (Rat) endosome to melanosome transport [GO:0035646]; intracellular protein transport [GO:0006886]; melanosome organization [GO:0032438]; vesicle-mediated transport [GO:0016192] GO:0005794; GO:0006886; GO:0016192; GO:0030131; GO:0030136; GO:0030665; GO:0031410; GO:0032438; GO:0035615; GO:0035646 8800 FUN_004035 67 0 75 108 13 NA NA NA NA NA NA NA 8801 FUN_004034 0 46 65 82 22 NA NA NA NA NA NA NA 8802 FUN_004037 50 55 72 78 97 NA NA NA NA NA NA NA 8803 FUN_004036 1771 925 1034 1912 223 NA NA NA NA NA NA NA 8804 FUN_004031 0 17 6 35 0 NA NA NA NA NA NA NA 8805 FUN_004030 258 1030 481 1122 668 NA NA NA NA NA NA NA 8806 FUN_004033 49 78 70 51 65 NA NA NA NA NA NA NA 8807 FUN_004032 1 14 96 60 9 NA NA NA NA NA NA NA 8808 FUN_018069 206 21 10 83 0 NA NA NA NA NA NA NA 8809 FUN_018068 75 71 24 143 102 NA NA NA NA NA NA NA 8810 FUN_018063 481 744 47 169 39 NA NA NA NA NA NA NA 8811 FUN_018062 7 4 2 0 4 NA NA NA NA NA NA NA 8812 FUN_018061 4551 669 4517 29 3078 NA NA NA NA NA NA NA 8813 FUN_018067 296 1374 10852 190 9730 ptg000012l:3910813-3974621 O60290 1.08e-60 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 8814 FUN_018067 296 1374 10852 190 9730 ptg000012l:3910813-3974621 O60290 1.08e-60 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 8815 FUN_018066 100 0 36 0 53 NA NA NA NA NA NA NA 8816 FUN_018065 986 20 1137 10 5 NA NA NA NA NA NA NA 8817 FUN_026138 133 112 110 229 113 NA NA NA NA NA NA NA 8818 FUN_026139 7 251 230 397 174 NA NA NA NA NA NA NA 8819 FUN_023328 466 177 54 549 1245 NA NA NA NA NA NA NA 8820 FUN_023329 167 709 52 538 92 NA NA NA NA NA NA NA 8821 FUN_026130 47 358 168 362 36 ptg000020l:5066786-5076500 Q60431 4.09e-32 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Mesocricetus auratus (Golden hamster) intracellular signal transduction [GO:0035556]; positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0035556; GO:0097153; GO:0097199; GO:0097200; GO:1902004 8822 FUN_023323 253 372 363 534 837 ptg000017l:6341274-6356631 Q80T41 8.61e-23 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0038039; GO:0042734; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 8823 FUN_026132 0 184 229 167 15 NA NA NA NA NA NA NA 8824 FUN_023321 5573 2582 1821 3048 3527 NA NA NA NA NA NA NA 8825 FUN_026134 0 0 9 12 14 NA NA NA NA NA NA NA 8826 FUN_026135 177 131 167 539 72 ptg000020l:5111514-5114194 P55866 2.45e-32 Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (xCPP32) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Xenopus laevis (African clawed frog) proteolysis [GO:0006508] GO:0004175; GO:0005737; GO:0006508; GO:0097200 8827 FUN_026136 38 221 112 262 70 NA NA NA NA NA NA NA 8828 FUN_025449 0 0 34 0 61 NA NA NA NA NA NA NA 8829 FUN_000325 35 18 0 0 17 NA NA NA NA NA NA NA 8830 FUN_000324 390 1308 1318 922 270 NA NA NA NA NA NA NA 8831 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 5.07e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8832 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 5.07e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8833 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 1.86e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8834 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 1.86e-30 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8835 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 6.97e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8836 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 6.97e-23 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8837 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 7.79e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8838 FUN_025441 158 77 61 171 220 ptg000019l:2694241-2724985 D3YXG0 6.04e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 8839 FUN_025440 0 0 0 21 0 NA NA NA NA NA NA NA 8840 FUN_025443 2271 1000 1164 1398 971 NA NA NA NA NA NA NA 8841 FUN_025442 478 248 207 571 439 NA NA NA NA NA NA NA 8842 FUN_025445 358 2566 11 14 6 NA NA NA NA NA NA NA 8843 FUN_041773 695 202 175 549 656 NA NA NA NA NA NA NA 8844 FUN_025447 242 0 0 0 405 ptg000019l:2816862-2822117 Q9UMR2 1.14e-25 ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; poly(A)+ mRNA export from nucleus [GO:0016973] GO:0003723; GO:0003724; GO:0004386; GO:0005524; GO:0005634; GO:0005635; GO:0005643; GO:0005654; GO:0005737; GO:0006406; GO:0010494; GO:0016020; GO:0016887; GO:0016973; GO:0070062 8845 FUN_035325 310 161 164 241 111 ptg000025l:6406733-6408022 A0A3M6TIF0 2.29e-149 NA NA NA NA 8846 FUN_035325 310 161 164 241 111 ptg000025l:6406733-6408022 A0A3M6TIF0 2.29e-149 NA NA NA NA 8847 FUN_041772 246 53 38 83 219 NA NA NA NA NA NA NA 8848 FUN_018399 432 139 0 0 134 NA NA NA NA NA NA NA 8849 FUN_018398 4477 2427 1716 1896 2802 NA NA NA NA NA NA NA 8850 FUN_035324 1251 573 305 265 222 NA NA NA NA NA NA NA 8851 FUN_018395 891 854 399 1465 1287 NA NA NA NA NA NA NA 8852 FUN_041775 4643 6552 4174 5770 5729 ptg000035l:7341499-7343073 P22232 7.58e-40 rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin) Xenopus laevis (African clawed frog) histone glutamine methylation [GO:1990258]; rRNA methylation [GO:0031167] GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0031167; GO:1990258; GO:1990259; GO:1990904 8853 FUN_041775 4643 6552 4174 5770 5729 ptg000035l:7341499-7343073 P22232 2.2e-21 rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin) Xenopus laevis (African clawed frog) histone glutamine methylation [GO:1990258]; rRNA methylation [GO:0031167] GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0031167; GO:1990258; GO:1990259; GO:1990904 8854 FUN_018397 688 655 537 747 671 ptg000012l:8828592-8829688 Q99JB0 3.16e-56 Krueppel-like factor 7 Mus musculus (Mouse) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dendrite morphogenesis [GO:0048813]; glucose homeostasis [GO:0042593]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0007409; GO:0007411; GO:0042593; GO:0045604; GO:0045893; GO:0045944; GO:0046872; GO:0048813; GO:0061179; GO:1904178 8855 FUN_018396 74 96 71 177 80 NA NA NA NA NA NA NA 8856 FUN_018391 1354 1252 354 1439 798 NA NA NA NA NA NA NA 8857 FUN_035327 172 100 74 183 123 NA NA NA NA NA NA NA 8858 FUN_018393 377 902 365 331 678 NA NA NA NA NA NA NA 8859 FUN_041774 21723 23241 16487 21078 15361 NA NA NA NA NA NA NA 8860 FUN_035326 43 31 17 30 99 NA NA NA NA NA NA NA 8861 FUN_000323 4606 3045 1897 3552 3370 ntLink_6:1516506-1542576 Q9QYF3 6.25e-29 Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; axo-dendritic protein transport [GO:0099640]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; developmental pigmentation [GO:0048066]; dopamine metabolic process [GO:0042417]; endoplasmic reticulum localization [GO:0051643]; establishment of endoplasmic reticulum localization to postsynapse [GO:0099089]; exocytosis [GO:0006887]; hair follicle maturation [GO:0048820]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; macroautophagy [GO:0016236]; melanin biosynthetic process [GO:0042438]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; myelination [GO:0042552]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuromuscular process controlling balance [GO:0050885]; odontogenesis [GO:0042476]; pigmentation [GO:0043473]; positive regulation of cellular response to insulin stimulus [GO:1900078]; positive regulation of cytochrome-c oxidase activity [GO:1904960]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; reactive gliosis [GO:0150103]; regulation of exocytosis [GO:0017157]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of postsynaptic cytosolic calcium ion concentration [GO:0099566]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192]; visual perception [GO:0007601] GO:0000146; GO:0000149; GO:0001726; GO:0001750; GO:0003774; GO:0003779; GO:0005509; GO:0005516; GO:0005524; GO:0005737; GO:0005790; GO:0005794; GO:0005829; GO:0005882; GO:0006582; GO:0006887; GO:0006892; GO:0007015; GO:0007268; GO:0007601; GO:0008021; GO:0015629; GO:0016020; GO:0016192; GO:0016236; GO:0016459; GO:0016461; GO:0017075; GO:0017157; GO:0019901; GO:0030048; GO:0030050; GO:0030073; GO:0030141; GO:0030318; GO:0030424; GO:0030425; GO:0031267; GO:0031585; GO:0031982; GO:0031987; GO:0032252; GO:0032400; GO:0032402; GO:0032433; GO:0032593; GO:0032869; GO:0033602; GO:0042417; GO:0042438; GO:0042470; GO:0042476; GO:0042552; GO:0042641; GO:0042642; GO:0042759; GO:0042802; GO:0043005; GO:0043008; GO:0043025; GO:0043473; GO:0044877; GO:0048066; GO:0048306; GO:0048820; GO:0050808; GO:0050885; GO:0051015; GO:0051643; GO:0051967; GO:0055037; GO:0065003; GO:0072659; GO:0097718; GO:0098685; GO:0098794; GO:0098871; GO:0098978; GO:0099089; GO:0099566; GO:0099640; GO:0150103; GO:1900078; GO:1903078; GO:1904754; GO:1904960; GO:1990904 8862 FUN_000323 4606 3045 1897 3552 3370 ntLink_6:1516506-1542576 Q9QYF3 1.42e-24 Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; actin filament-based movement [GO:0030048]; axo-dendritic protein transport [GO:0099640]; cellular response to insulin stimulus [GO:0032869]; chemical synaptic transmission [GO:0007268]; developmental pigmentation [GO:0048066]; dopamine metabolic process [GO:0042417]; endoplasmic reticulum localization [GO:0051643]; establishment of endoplasmic reticulum localization to postsynapse [GO:0099089]; exocytosis [GO:0006887]; hair follicle maturation [GO:0048820]; insulin secretion [GO:0030073]; locomotion involved in locomotory behavior [GO:0031987]; long-chain fatty acid biosynthetic process [GO:0042759]; macroautophagy [GO:0016236]; melanin biosynthetic process [GO:0042438]; melanin metabolic process [GO:0006582]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; myelination [GO:0042552]; negative regulation of dopamine secretion [GO:0033602]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; neuromuscular process controlling balance [GO:0050885]; odontogenesis [GO:0042476]; pigmentation [GO:0043473]; positive regulation of cellular response to insulin stimulus [GO:1900078]; positive regulation of cytochrome-c oxidase activity [GO:1904960]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; post-Golgi vesicle-mediated transport [GO:0006892]; protein localization to plasma membrane [GO:0072659]; protein-containing complex assembly [GO:0065003]; reactive gliosis [GO:0150103]; regulation of exocytosis [GO:0017157]; regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO:0031585]; regulation of postsynaptic cytosolic calcium ion concentration [GO:0099566]; secretory granule localization [GO:0032252]; synapse organization [GO:0050808]; vesicle transport along actin filament [GO:0030050]; vesicle-mediated transport [GO:0016192]; visual perception [GO:0007601] GO:0000146; GO:0000149; GO:0001726; GO:0001750; GO:0003774; GO:0003779; GO:0005509; GO:0005516; GO:0005524; GO:0005737; GO:0005790; GO:0005794; GO:0005829; GO:0005882; GO:0006582; GO:0006887; GO:0006892; GO:0007015; GO:0007268; GO:0007601; GO:0008021; GO:0015629; GO:0016020; GO:0016192; GO:0016236; GO:0016459; GO:0016461; GO:0017075; GO:0017157; GO:0019901; GO:0030048; GO:0030050; GO:0030073; GO:0030141; GO:0030318; GO:0030424; GO:0030425; GO:0031267; GO:0031585; GO:0031982; GO:0031987; GO:0032252; GO:0032400; GO:0032402; GO:0032433; GO:0032593; GO:0032869; GO:0033602; GO:0042417; GO:0042438; GO:0042470; GO:0042476; GO:0042552; GO:0042641; GO:0042642; GO:0042759; GO:0042802; GO:0043005; GO:0043008; GO:0043025; GO:0043473; GO:0044877; GO:0048066; GO:0048306; GO:0048820; GO:0050808; GO:0050885; GO:0051015; GO:0051643; GO:0051967; GO:0055037; GO:0065003; GO:0072659; GO:0097718; GO:0098685; GO:0098794; GO:0098871; GO:0098978; GO:0099089; GO:0099566; GO:0099640; GO:0150103; GO:1900078; GO:1903078; GO:1904754; GO:1904960; GO:1990904 8863 FUN_044260 2 2 13 9 67 NA NA NA NA NA NA NA 8864 FUN_000322 1055 866 640 723 543 NA NA NA NA NA NA NA 8865 FUN_035320 48 10 0 34 0 NA NA NA NA NA NA NA 8866 FUN_044262 4 11 27 33 99 NA NA NA NA NA NA NA 8867 FUN_035322 73 11 21 46 5 NA NA NA NA NA NA NA 8868 FUN_001948 1937 1210 1216 1812 2320 ntLink_6:18174033-18200319 Q6ZQB6 3.86e-37 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2) Mus musculus (Mouse) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; phosphorylation [GO:0016310]; sensory perception of sound [GO:0007605] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0005524; GO:0005829; GO:0006020; GO:0007605; GO:0016310; GO:0032958; GO:0033857; GO:0052723; GO:0052724 8869 FUN_001948 1937 1210 1216 1812 2320 ntLink_6:18174033-18200319 Q6ZQB6 4.41e-34 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2) Mus musculus (Mouse) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; phosphorylation [GO:0016310]; sensory perception of sound [GO:0007605] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0005524; GO:0005829; GO:0006020; GO:0007605; GO:0016310; GO:0032958; GO:0033857; GO:0052723; GO:0052724 8870 FUN_001948 1937 1210 1216 1812 2320 ntLink_6:18174033-18200319 Q6ZQB6 1.51e-24 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2) Mus musculus (Mouse) inositol metabolic process [GO:0006020]; inositol phosphate biosynthetic process [GO:0032958]; phosphorylation [GO:0016310]; sensory perception of sound [GO:0007605] GO:0000827; GO:0000828; GO:0000829; GO:0000832; GO:0005524; GO:0005829; GO:0006020; GO:0007605; GO:0016310; GO:0032958; GO:0033857; GO:0052723; GO:0052724 8871 FUN_028846 133 90 82 92 67 ptg000022l:4945675-4946797 Q99999 5.92e-61 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Homo sapiens (Human) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; myelination [GO:0042552]; protein N-linked glycosylation [GO:0006487]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0005886; GO:0006487; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0016020; GO:0042552; GO:0046486; GO:0050694 8872 FUN_036675 0 0 10 11 35 NA NA NA NA NA NA NA 8873 FUN_033879 1551 429 419 1244 1316 NA NA NA NA NA NA NA 8874 FUN_033878 1160 861 521 1073 842 NA NA NA NA NA NA NA 8875 FUN_033873 5359 3917 1681 3101 1769 ptg000024l:2119083-2128669 Q91853 6.72e-26 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0046872 8876 FUN_033873 5359 3917 1681 3101 1769 ptg000024l:2119083-2128669 Q91853 4.29e-24 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0046872 8877 FUN_033873 5359 3917 1681 3101 1769 ptg000024l:2119083-2128669 Q91853 7.45e-23 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Xenopus laevis (African clawed frog) NA GO:0003677; GO:0005634; GO:0046872 8878 FUN_033872 117 51 129 78 141 NA NA NA NA NA NA NA 8879 FUN_033871 1543 1060 732 1832 1738 NA NA NA NA NA NA NA 8880 FUN_033870 6 24 0 25 0 NA NA NA NA NA NA NA 8881 FUN_033877 40 25 195 246 452 NA NA NA NA NA NA NA 8882 FUN_033876 368 171 178 312 364 NA NA NA NA NA NA NA 8883 FUN_033875 1265 580 621 881 1624 NA NA NA NA NA NA NA 8884 FUN_033874 5165 3159 1253 2619 3910 NA NA NA NA NA NA NA 8885 FUN_018939 0 0 0 0 26 ptg000012l:15430519-15437969 Q01490 4.68e-24 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) Orpinomyces sp. (strain PC-2) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005788; GO:0006457 8886 FUN_036679 0 0 0 0 11 NA NA NA NA NA NA NA 8887 FUN_018930 0 0 0 0 44 NA NA NA NA NA NA NA 8888 FUN_018933 372 161 73 111 245 NA NA NA NA NA NA NA 8889 FUN_040074 315 420 283 335 375 NA NA NA NA NA NA NA 8890 FUN_018935 93 36 72 46 203 NA NA NA NA NA NA NA 8891 FUN_018934 45 29 16 36 82 NA NA NA NA NA NA NA 8892 FUN_018936 307 58 122 90 1199 NA NA NA NA NA NA NA 8893 FUN_005849 0 0 3 0 23 NA NA NA NA NA NA NA 8894 FUN_005848 0 0 0 0 18 NA NA NA NA NA NA NA 8895 FUN_005843 16 0 0 0 0 NA NA NA NA NA NA NA 8896 FUN_005841 0 0 0 0 54 NA NA NA NA NA NA NA 8897 FUN_005840 0 0 0 2 19 NA NA NA NA NA NA NA 8898 FUN_005846 4 29 47 2 0 NA NA NA NA NA NA NA 8899 FUN_005844 0 0 0 0 7 NA NA NA NA NA NA NA 8900 FUN_012778 836 1503 1010 657 848 ptg000008l:12707112-12708307 A7RL75 1.23e-25 Tetratricopeptide repeat protein 36 homolog (TPR repeat protein 36 homolog) Nematostella vectensis (Starlet sea anemone) cilium assembly [GO:0060271] GO:0060271 8901 FUN_026734 241 125 40 125 51 ptg000020l:12916638-12919091 Q8CBH5 2.73e-56 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 8902 FUN_037289 811 935 673 588 765 NA NA NA NA NA NA NA 8903 FUN_042107 477 830 617 345 453 ptg000036l:632871-634557 Q4QR62 3.37e-23 Mitochondrial import inner membrane translocase subunit Tim10-A Xenopus laevis (African clawed frog) protein transport [GO:0015031] GO:0005743; GO:0015031; GO:0046872 8904 FUN_042106 41 1909 38 1159 133 NA NA NA NA NA NA NA 8905 FUN_042104 1099 384 1546 796 2456 NA NA NA NA NA NA NA 8906 FUN_042103 364 4765 250 8304 216 NA NA NA NA NA NA NA 8907 FUN_042102 0 7 0 0 20 NA NA NA NA NA NA NA 8908 FUN_042101 46 28 21 0 98 NA NA NA NA NA NA NA 8909 FUN_006302 264 40 192 396 622 NA NA NA NA NA NA NA 8910 FUN_042109 323 429 495 312 443 NA NA NA NA NA NA NA 8911 FUN_036960 92 29 41 93 127 ptg000026l:3902089-3905909 Q68F72 3.5e-37 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 8912 FUN_036966 678 288 307 541 463 ptg000026l:3971988-3976124 Q68F72 2.52e-42 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 8913 FUN_036967 2148 1043 869 1382 1557 ptg000026l:3978640-3987071 Q5BJQ2 9.41e-34 Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (Protein FAM63A) Rattus norvegicus (Rat) protein K48-linked deubiquitination [GO:0071108] GO:0004843; GO:0016604; GO:0016807; GO:0036435; GO:0071108; GO:1990380 8914 FUN_036964 457 278 173 360 242 ptg000026l:3936923-3967063 Q68F72 3.6e-34 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 8915 FUN_036964 457 278 173 360 242 ptg000026l:3936923-3967063 Q68F72 3.73e-34 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 8916 FUN_036964 457 278 173 360 242 ptg000026l:3936923-3967063 Q68F72 2.61e-29 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 8917 FUN_036965 55 24 0 10 6 NA NA NA NA NA NA NA 8918 FUN_029294 87 128 42 164 100 NA NA NA NA NA NA NA 8919 FUN_029295 85 53 19 87 86 ptg000023l:174085-174682 A2VDD2 3e-29 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 8920 FUN_035703 0 0 10 0 21 NA NA NA NA NA NA NA 8921 FUN_035702 578 682 399 21 851 NA NA NA NA NA NA NA 8922 FUN_035701 714 432 631 435 704 ptg000025l:10791093-10805346 F4I7I0 1.08e-21 Alanine aminotransferase 1, mitochondrial (AtAlaAT1) (AtAlaATc) (EC 2.6.1.2) (Alanine-2-oxoglutarate aminotransferase 4) (EC 2.6.1.-) Arabidopsis thaliana (Mouse-ear cress) biosynthetic process [GO:0009058]; cellular response to hypoxia [GO:0071456]; L-alanine catabolic process, by transamination [GO:0019481]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666] GO:0001666; GO:0004021; GO:0005524; GO:0005634; GO:0005739; GO:0009058; GO:0019481; GO:0030170; GO:0046686; GO:0071456 8923 FUN_035700 128 0 35 33 510 NA NA NA NA NA NA NA 8924 FUN_035707 523 289 177 522 452 NA NA NA NA NA NA NA 8925 FUN_035706 998 847 898 950 388 NA NA NA NA NA NA NA 8926 FUN_035705 263 191 29 32 166 NA NA NA NA NA NA NA 8927 FUN_035709 621 1044 311 576 375 NA NA NA NA NA NA NA 8928 FUN_035708 982 1353 548 996 834 NA NA NA NA NA NA NA 8929 FUN_003871 1858 578 9430 1005 1760 ntLink_8:16350255-16359539 A0A0C2SRU0 3.3e-76 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 8930 FUN_003871 1858 578 9430 1005 1760 ntLink_8:16350255-16359539 A0A0C2SRU0 5.53e-75 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 8931 FUN_003872 107 43 677 45 71 NA NA NA NA NA NA NA 8932 FUN_003873 11 2 0 3 7 NA NA NA NA NA NA NA 8933 FUN_003874 0 0 0 0 26 ntLink_8:16378900-16380909 A0A0C2SRU0 2.71e-81 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 8934 FUN_003875 69 20 261 31 37 ntLink_8:16392614-16393700 A0A0C2SRU0 7.17e-81 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 8935 FUN_003876 137 176 54 154 87 ntLink_8:16411282-16412641 A0A0C2SRU0 1.4e-76 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 8936 FUN_003877 116 104 35 97 142 NA NA NA NA NA NA NA 8937 FUN_003878 587 396 200 398 504 NA NA NA NA NA NA NA 8938 FUN_003879 1 1 1 1 18 NA NA NA NA NA NA NA 8939 FUN_031464 1822 1571 1101 1471 1571 NA NA NA NA NA NA NA 8940 FUN_031465 629 733 470 586 599 ptg000023l:21767556-21771511 Q2TBI8 5.2e-25 Uridine diphosphate glucose pyrophosphatase NUDT22 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 22) (Nudix motif 22) Bos taurus (Bovine) NA GO:0008768; GO:0046872; GO:0052751 8941 FUN_031462 104 198 104 127 251 ptg000023l:21752904-21754096 Q8D3M4 4.93e-25 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 8942 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 5.66e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8943 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 4.2e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8944 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 1.24e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8945 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 1.06e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8946 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 1.22e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8947 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 3.78e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8948 FUN_031460 66 54 117 31 847 ptg000023l:21735044-21737109 Q7RTR2 2.56e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 8949 FUN_031461 2 1 197 0 448 NA NA NA NA NA NA NA 8950 FUN_037705 616 237 260 299 381 NA NA NA NA NA NA NA 8951 FUN_037704 2 0 0 43 9 NA NA NA NA NA NA NA 8952 FUN_037707 2746 651 295 1602 586 NA NA NA NA NA NA NA 8953 FUN_037706 446 73 71 74 157 NA NA NA NA NA NA NA 8954 FUN_037701 1850 1012 645 1386 1076 NA NA NA NA NA NA NA 8955 FUN_037700 896 748 676 782 986 ptg000026l:12552956-12558462 Q6DCC6 4.51e-27 Putative GTP-binding protein 6 Xenopus laevis (African clawed frog) NA GO:0005525; GO:0046872 8956 FUN_037703 265 263 155 291 187 NA NA NA NA NA NA NA 8957 FUN_037702 2952 2536 1864 2610 1926 NA NA NA NA NA NA NA 8958 FUN_037709 2476 1456 1395 2202 2356 ptg000026l:12652273-12669778 Q5HYK7 3.18e-21 SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; positive regulation of membrane protein ectodomain proteolysis [GO:0051044]; regulation of cell morphogenesis [GO:0022604] GO:0005654; GO:0005829; GO:0005886; GO:0007010; GO:0022604; GO:0051044; GO:0070064 8959 FUN_037708 687 154 140 299 207 NA NA NA NA NA NA NA 8960 FUN_025734 612 420 166 468 468 NA NA NA NA NA NA NA 8961 FUN_001658 6854 4881 4063 7898 6629 ntLink_6:14670179-14682227 P23591 1.3e-21 GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Transplantation antigen P35B) (Tum-P35B antigen) Mus musculus (Mouse) 'de novo' GDP-L-fucose biosynthetic process [GO:0042351]; GDP-mannose metabolic process [GO:0019673]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904906]; T cell mediated cytotoxicity [GO:0001913] GO:0001913; GO:0010595; GO:0019673; GO:0042351; GO:0042802; GO:0047918; GO:0050577; GO:1904906 8962 FUN_001659 6 0 14 10 88 NA NA NA NA NA NA NA 8963 FUN_028335 833 104 0 276 240 NA NA NA NA NA NA NA 8964 FUN_001653 3636 1290 2512 1971 2439 NA NA NA NA NA NA NA 8965 FUN_001650 929 25 661 39 2049 NA NA NA NA NA NA NA 8966 FUN_032630 2315 1231 1345 2993 1906 NA NA NA NA NA NA NA 8967 FUN_001656 2846 2958 1896 3588 3438 ntLink_6:14654564-14656646 A6QP05 8.85e-68 Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1) (Protein SDR40C1) Bos taurus (Bovine) NA GO:0016491 8968 FUN_001657 2015 1994 1165 1869 1842 NA NA NA NA NA NA NA 8969 FUN_001654 28632 24217 11954 18707 17787 ntLink_6:14624749-14629298 P63245 9.63e-46 Receptor of activated protein C kinase 1 (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell cycle [GO:0007049]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; gastrulation [GO:0007369]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of translation [GO:0017148]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; pigmentation [GO:0043473]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gastrulation [GO:2000543]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex assembly [GO:0031334]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; rescue of stalled ribosome [GO:0072344]; rhythmic process [GO:0048511]; translation [GO:0006412] GO:0001649; GO:0001891; GO:0001934; GO:0005080; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006412; GO:0006919; GO:0007049; GO:0007205; GO:0007369; GO:0008200; GO:0008656; GO:0010629; GO:0015935; GO:0016020; GO:0016567; GO:0017148; GO:0019899; GO:0019903; GO:0030178; GO:0030292; GO:0030308; GO:0030332; GO:0030335; GO:0030425; GO:0030496; GO:0030971; GO:0031334; GO:0032091; GO:0032436; GO:0032880; GO:0033137; GO:0035591; GO:0042169; GO:0042803; GO:0042998; GO:0043005; GO:0043022; GO:0043025; GO:0043065; GO:0043204; GO:0043473; GO:0043547; GO:0044297; GO:0045182; GO:0045879; GO:0048471; GO:0048511; GO:0050765; GO:0051302; GO:0051343; GO:0051434; GO:0051726; GO:0051898; GO:0051901; GO:0071333; GO:0071363; GO:0072344; GO:1903076; GO:1903208; GO:1990630; GO:2000114; GO:2000543; GO:2001244 8970 FUN_001654 28632 24217 11954 18707 17787 ntLink_6:14624749-14629298 P63245 4.86e-21 Receptor of activated protein C kinase 1 (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein kinase C 1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed] Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cell cycle [GO:0007049]; cellular response to glucose stimulus [GO:0071333]; cellular response to growth factor stimulus [GO:0071363]; gastrulation [GO:0007369]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron death [GO:1903208]; negative regulation of peptidyl-serine phosphorylation [GO:0033137]; negative regulation of phagocytosis [GO:0050765]; negative regulation of protein binding [GO:0032091]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of translation [GO:0017148]; negative regulation of Wnt signaling pathway [GO:0030178]; osteoblast differentiation [GO:0001649]; pigmentation [GO:0043473]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cell migration [GO:0030335]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; positive regulation of gastrulation [GO:2000543]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of GTPase activity [GO:0043547]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein-containing complex assembly [GO:0031334]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of establishment of cell polarity [GO:2000114]; regulation of protein localization [GO:0032880]; regulation of protein localization to plasma membrane [GO:1903076]; rescue of stalled ribosome [GO:0072344]; rhythmic process [GO:0048511]; translation [GO:0006412] GO:0001649; GO:0001891; GO:0001934; GO:0005080; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006412; GO:0006919; GO:0007049; GO:0007205; GO:0007369; GO:0008200; GO:0008656; GO:0010629; GO:0015935; GO:0016020; GO:0016567; GO:0017148; GO:0019899; GO:0019903; GO:0030178; GO:0030292; GO:0030308; GO:0030332; GO:0030335; GO:0030425; GO:0030496; GO:0030971; GO:0031334; GO:0032091; GO:0032436; GO:0032880; GO:0033137; GO:0035591; GO:0042169; GO:0042803; GO:0042998; GO:0043005; GO:0043022; GO:0043025; GO:0043065; GO:0043204; GO:0043473; GO:0043547; GO:0044297; GO:0045182; GO:0045879; GO:0048471; GO:0048511; GO:0050765; GO:0051302; GO:0051343; GO:0051434; GO:0051726; GO:0051898; GO:0051901; GO:0071333; GO:0071363; GO:0072344; GO:1903076; GO:1903208; GO:1990630; GO:2000114; GO:2000543; GO:2001244 8971 FUN_001655 13358 6558 5490 7620 8418 ntLink_6:14629652-14652118 Q27954 4.12e-30 Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005179; GO:0005198; GO:0005576; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126 8972 FUN_001655 13358 6558 5490 7620 8418 ntLink_6:14629652-14652118 Q27954 4.12e-30 Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005179; GO:0005198; GO:0005576; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126 8973 FUN_001655 13358 6558 5490 7620 8418 ntLink_6:14629652-14652118 Q27954 6.15e-29 Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005179; GO:0005198; GO:0005576; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126 8974 FUN_001655 13358 6558 5490 7620 8418 ntLink_6:14629652-14652118 Q27954 6.15e-29 Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin] Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005179; GO:0005198; GO:0005576; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126 8975 FUN_032287 3404 2456 1524 2305 1751 NA NA NA NA NA NA NA 8976 FUN_032286 605 727 767 541 663 ptg000023l:30503507-30504612 Q28HF8 3.25e-130 Sodium/bile acid cotransporter 7 (Na(+)/bile acid cotransporter 7) (Solute carrier family 10 member 7) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0000139; GO:0005789; GO:0005886; GO:0006814; GO:0015293 8977 FUN_032285 281 197 259 141 119 ptg000023l:30502755-30503307 P26186 2.09e-37 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) DNA modification [GO:0006304]; DNA repair [GO:0006281]; methylation [GO:0032259] GO:0003677; GO:0003908; GO:0005634; GO:0006281; GO:0006304; GO:0032259; GO:0046872 8978 FUN_032284 2132 1387 1121 1655 1647 ptg000023l:30492759-30502236 O15321 5.11e-25 Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70) Homo sapiens (Human) autophagy [GO:0006914]; protein localization to membrane [GO:0072657] GO:0000421; GO:0005765; GO:0006914; GO:0016020; GO:0031410; GO:0072657 8979 FUN_032284 2132 1387 1121 1655 1647 ptg000023l:30492759-30502236 O15321 1.69e-21 Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70) Homo sapiens (Human) autophagy [GO:0006914]; protein localization to membrane [GO:0072657] GO:0000421; GO:0005765; GO:0006914; GO:0016020; GO:0031410; GO:0072657 8980 FUN_032283 653 421 439 489 634 NA NA NA NA NA NA NA 8981 FUN_032282 144 72 63 72 114 ptg000023l:30484346-30486347 Q6IRM9 1.48e-38 Protein zwilch homolog Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic spindle assembly checkpoint signaling [GO:0007094] GO:0007094; GO:0051301; GO:1990423 8982 FUN_032281 338 288 161 286 273 NA NA NA NA NA NA NA 8983 FUN_032280 1556 1266 566 840 816 NA NA NA NA NA NA NA 8984 FUN_032289 3580 3679 2668 2340 1455 NA NA NA NA NA NA NA 8985 FUN_032288 3570 2393 1575 2444 2437 ptg000023l:30520825-30534786 P52824 3.45e-21 Diacylglycerol kinase theta (DAG kinase theta) (DGKtheta) (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) Homo sapiens (Human) cAMP-mediated signaling [GO:0019933]; diacylglycerol metabolic process [GO:0046339]; G protein-coupled receptor signaling pathway [GO:0007186]; glycerolipid metabolic process [GO:0046486]; intracellular signal transduction [GO:0035556]; lipid phosphorylation [GO:0046834]; negative regulation of gene expression [GO:0010629]; negative regulation of peptidyl-threonine phosphorylation [GO:0010801]; peptidyl-serine phosphorylation [GO:0018105]; phosphatidic acid biosynthetic process [GO:0006654]; platelet activation [GO:0030168]; positive regulation of gene expression [GO:0010628]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; protein kinase C signaling [GO:0070528]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of cholesterol metabolic process [GO:0090181]; regulation of cortisol biosynthetic process [GO:2000064]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of gluconeogenesis [GO:0006111]; regulation of progesterone biosynthetic process [GO:2000182]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of TORC1 signaling [GO:1903432]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ATP [GO:0033198]; response to cAMP [GO:0051591]; thrombin-activated receptor signaling pathway [GO:0070493] GO:0004143; GO:0005524; GO:0005634; GO:0005737; GO:0005768; GO:0005829; GO:0005856; GO:0005886; GO:0006111; GO:0006357; GO:0006654; GO:0007186; GO:0007205; GO:0008277; GO:0010628; GO:0010629; GO:0010801; GO:0012506; GO:0016363; GO:0016607; GO:0018105; GO:0019900; GO:0019933; GO:0030168; GO:0030297; GO:0033198; GO:0035556; GO:0043274; GO:0046339; GO:0046486; GO:0046834; GO:0046872; GO:0050731; GO:0051591; GO:0070493; GO:0070528; GO:0090181; GO:0098793; GO:0098794; GO:0098978; GO:0140297; GO:1900242; GO:1903432; GO:2000064; GO:2000182 8986 FUN_008264 180 62 21 209 198 ptg000002l:9791060-9792278 A4IHR5 6.48e-58 Insulinoma-associated protein 1 (Zinc finger protein IA-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endocrine pancreas development [GO:0031018]; endodermal cell differentiation [GO:0035987]; gland development [GO:0048732]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; pancreatic A cell differentiation [GO:0003310]; transdifferentiation [GO:0060290]; type B pancreatic cell differentiation [GO:0003309] GO:0000122; GO:0000978; GO:0003309; GO:0003310; GO:0003700; GO:0005634; GO:0007399; GO:0017053; GO:0031018; GO:0031490; GO:0035987; GO:0046872; GO:0048732; GO:0060290 8987 FUN_008265 188 39 88 414 208 NA NA NA NA NA NA NA 8988 FUN_008266 893 518 394 445 638 NA NA NA NA NA NA NA 8989 FUN_008260 8956 8347 4901 10791 12775 ptg000002l:9746006-9751661 P55010 1.6e-23 Eukaryotic translation initiation factor 5 (eIF-5) Homo sapiens (Human) formation of cytoplasmic translation initiation complex [GO:0001732]; formation of translation preinitiation complex [GO:0001731]; regulation of translational initiation [GO:0006446] GO:0001731; GO:0001732; GO:0003723; GO:0003743; GO:0005092; GO:0005525; GO:0005737; GO:0005829; GO:0005886; GO:0006446; GO:0045202; GO:0045296; GO:0071074 8990 FUN_008261 1151 734 617 905 1098 ptg000002l:9752413-9754192 A4IFM3 1.56e-35 Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) Bos taurus (Bovine) retinol metabolic process [GO:0042572]; steroid metabolic process [GO:0008202] GO:0004745; GO:0005737; GO:0008202; GO:0016491; GO:0042572; GO:0043231 8991 FUN_008262 940 592 590 837 942 ptg000002l:9761499-9773517 O96005 2.93e-23 Putative lipid scramblase CLPTM1 (Cleft lip and palate transmembrane protein 1) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; regulation of T cell differentiation in thymus [GO:0033081] GO:0005886; GO:0009897; GO:0012505; GO:0016020; GO:0030154; GO:0033081; GO:0050811; GO:0098982; GO:0099072 8992 FUN_008263 172 218 187 407 404 ptg000002l:9774679-9779544 Q3UN02 1.47e-52 Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (EC 2.3.1.51) (Acyl-CoA:lysocardiolipin acyltransferase 1) Mus musculus (Mouse) cardiolipin acyl-chain remodeling [GO:0035965]; CDP-diacylglycerol biosynthetic process [GO:0016024]; phosphatidylinositol acyl-chain remodeling [GO:0036149] GO:0003841; GO:0005783; GO:0005789; GO:0005829; GO:0012505; GO:0016024; GO:0016746; GO:0035965; GO:0036149 8993 FUN_005025 474 727 427 404 185 NA NA NA NA NA NA NA 8994 FUN_005024 1165 561 738 1138 786 NA NA NA NA NA NA NA 8995 FUN_005027 1465 1507 609 677 535 NA NA NA NA NA NA NA 8996 FUN_005026 1706 3182 637 1601 1484 NA NA NA NA NA NA NA 8997 FUN_005021 61 27 14 58 144 NA NA NA NA NA NA NA 8998 FUN_005023 548 350 357 316 255 NA NA NA NA NA NA NA 8999 FUN_005022 239 220 170 146 277 NA NA NA NA NA NA NA 9000 FUN_031379 359 137 270 23 275 ptg000023l:20326861-20335054 Q7RTR2 2.6e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9001 FUN_031379 359 137 270 23 275 ptg000023l:20326861-20335054 Q7RTR2 3.4e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9002 FUN_031379 359 137 270 23 275 ptg000023l:20326861-20335054 Q7RTR2 1.95e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9003 FUN_031379 359 137 270 23 275 ptg000023l:20326861-20335054 Q7RTR2 1.54e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9004 FUN_031379 359 137 270 23 275 ptg000023l:20326861-20335054 Q7RTR2 1.8e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9005 FUN_005029 645 349 212 423 310 NA NA NA NA NA NA NA 9006 FUN_005028 39 0 4 21 4 NA NA NA NA NA NA NA 9007 FUN_032634 6 2 10 2 5 NA NA NA NA NA NA NA 9008 FUN_039144 6 0 9 0 26 NA NA NA NA NA NA NA 9009 FUN_025951 1784 799 338 599 615 ptg000020l:2352820-2360416 E2RFJ3 1.73e-44 Solute carrier family 40 protein member 1 (Ferroportin-1) (Iron-regulated transporter 1) Canis lupus familiaris (Dog) (Canis familiaris) iron ion homeostasis [GO:0055072]; iron ion transmembrane transport [GO:0034755] GO:0005381; GO:0016323; GO:0017046; GO:0034755; GO:0046872; GO:0055072 9010 FUN_025951 1784 799 338 599 615 ptg000020l:2352820-2360416 E2RFJ3 1.09e-22 Solute carrier family 40 protein member 1 (Ferroportin-1) (Iron-regulated transporter 1) Canis lupus familiaris (Dog) (Canis familiaris) iron ion homeostasis [GO:0055072]; iron ion transmembrane transport [GO:0034755] GO:0005381; GO:0016323; GO:0017046; GO:0034755; GO:0046872; GO:0055072 9011 FUN_032863 13 0 0 8 33 NA NA NA NA NA NA NA 9012 FUN_032862 0 9 0 17 0 NA NA NA NA NA NA NA 9013 FUN_032861 26 6 9 8 2 NA NA NA NA NA NA NA 9014 FUN_032860 9 0 0 0 0 NA NA NA NA NA NA NA 9015 FUN_032867 0 0 0 0 7 NA NA NA NA NA NA NA 9016 FUN_032869 2 25 0 4 19 NA NA NA NA NA NA NA 9017 FUN_004778 50 22 0 0 24 NA NA NA NA NA NA NA 9018 FUN_004779 15274 11569 6565 8950 5058 NA NA NA NA NA NA NA 9019 FUN_004772 256 121 32 190 240 ntLink_8:26867299-26868103 P84239 2.19e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9020 FUN_004773 316 141 44 230 258 NA NA NA NA NA NA NA 9021 FUN_004770 519 275 103 256 305 ntLink_8:26863834-26864206 P69070 2.49e-59 Histone H2B Salmo trutta (Brown trout) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9022 FUN_004771 89 89 64 114 50 ntLink_8:26866329-26867166 Q6LAF1 5.78e-50 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9023 FUN_004776 6262 6397 2459 3969 2473 ntLink_8:26885367-26900563 Q9UDY8 4.14e-26 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; B cell activation [GO:0042113]; B-1 B cell differentiation [GO:0001923]; defense response [GO:0006952]; innate immune response [GO:0045087]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of apoptotic process [GO:0043066]; nuclear export [GO:0051168]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; regulation of apoptotic process [GO:0042981]; regulation of T cell receptor signaling pathway [GO:0050856]; response to fungus [GO:0009620]; T cell proliferation [GO:0042098]; T cell receptor signaling pathway [GO:0050852] GO:0001650; GO:0001923; GO:0002020; GO:0002096; GO:0002726; GO:0004175; GO:0004197; GO:0004842; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006952; GO:0007250; GO:0008233; GO:0009620; GO:0031398; GO:0031663; GO:0032449; GO:0032731; GO:0032743; GO:0032991; GO:0036094; GO:0042098; GO:0042113; GO:0042802; GO:0042981; GO:0043066; GO:0043123; GO:0043280; GO:0043621; GO:0045087; GO:0048471; GO:0050852; GO:0050856; GO:0051092; GO:0051168; GO:0051603; GO:2000321 9024 FUN_004777 2751 3086 2377 3129 2058 NA NA NA NA NA NA NA 9025 FUN_004774 713 455 177 433 357 NA NA NA NA NA NA NA 9026 FUN_004775 7 0 0 0 13 NA NA NA NA NA NA NA 9027 FUN_040249 45 38 120 42 0 ptg000031l:5885687-5892077 Q15818 5.96e-25 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 9028 FUN_040246 79 94 103 59 66 ptg000031l:5848729-5854299 Q15818 8.82e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 9029 FUN_040247 21 33 33 19 5 ptg000031l:5855072-5864143 Q15818 1.42e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 9030 FUN_040247 21 33 33 19 5 ptg000031l:5855072-5864143 Q15818 2.46e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 9031 FUN_040244 7865 6925 4592 5301 4045 ptg000031l:5830990-5836799 P19112 2.6e-25 Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; cellular hyperosmotic salinity response [GO:0071475]; cellular hypotonic salinity response [GO:0071477]; cellular response to cAMP [GO:0071320]; cellular response to insulin stimulus [GO:0032869]; cellular response to magnesium ion [GO:0071286]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; cellular response to raffinose [GO:0097403]; cellular response to xenobiotic stimulus [GO:0071466]; dephosphorylation [GO:0016311]; fructose 1,6-bisphosphate metabolic process [GO:0030388]; fructose 6-phosphate metabolic process [GO:0006002]; fructose metabolic process [GO:0006000]; gluconeogenesis [GO:0006094]; negative regulation of cell growth [GO:0030308]; negative regulation of glycolytic process [GO:0045820]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gluconeogenesis [GO:0006111]; response to cold [GO:0009409]; response to metformin [GO:1901558]; response to nutrient levels [GO:0031667]; sucrose biosynthetic process [GO:0005986] GO:0000122; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0005975; GO:0005986; GO:0006000; GO:0006002; GO:0006094; GO:0006111; GO:0009409; GO:0016208; GO:0016311; GO:0030308; GO:0030388; GO:0031667; GO:0032869; GO:0042132; GO:0042802; GO:0045820; GO:0046580; GO:0046872; GO:0048029; GO:0061629; GO:0071286; GO:0071320; GO:0071466; GO:0071475; GO:0071477; GO:0097403; GO:1901558; GO:1904628 9032 FUN_040242 1174 486 339 714 498 ptg000031l:5807489-5811562 Q5ZK21 8.88e-67 Integrator complex subunit 14 (von Willebrand factor A domain-containing protein 9) Gallus gallus (Chicken) snRNA 3'-end processing [GO:0034472] GO:0032039; GO:0034472 9033 FUN_040243 5167 4585 3801 4980 4063 NA NA NA NA NA NA NA 9034 FUN_040240 1655 1441 1130 2176 1218 NA NA NA NA NA NA NA 9035 FUN_040241 3023 2422 1451 3427 2147 ptg000031l:5802057-5805338 Q7ZVZ7 8.37e-114 Alpha/beta hydrolase domain-containing protein 17C (Abhydrolase domain-containing protein 17C) (EC 3.1.2.22) Danio rerio (Zebrafish) (Brachydanio rerio) protein depalmitoylation [GO:0002084]; regulation of postsynapse organization [GO:0099175] GO:0002084; GO:0005886; GO:0008474; GO:0010008; GO:0043197; GO:0055038; GO:0098839; GO:0099175 9036 FUN_040241 3023 2422 1451 3427 2147 ptg000031l:5802057-5805338 Q7ZVZ7 4.44e-32 Alpha/beta hydrolase domain-containing protein 17C (Abhydrolase domain-containing protein 17C) (EC 3.1.2.22) Danio rerio (Zebrafish) (Brachydanio rerio) protein depalmitoylation [GO:0002084]; regulation of postsynapse organization [GO:0099175] GO:0002084; GO:0005886; GO:0008474; GO:0010008; GO:0043197; GO:0055038; GO:0098839; GO:0099175 9037 FUN_034421 1742 2104 2073 1833 661 ptg000024l:8746973-8748842 Q3MHQ7 5.97e-54 Lysoplasmalogenase-like protein TMEM86A (Transmembrane protein 86A) Bos taurus (Bovine) NA GO:0016020; GO:0047408; GO:0047409 9038 FUN_034420 8998 6532 5140 9465 7970 ptg000024l:8725220-8739504 Q9Y6R1 2.91e-43 Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1) Homo sapiens (Human) bicarbonate transport [GO:0015701]; ion homeostasis [GO:0050801]; positive regulation of glycolytic process [GO:0045821]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0005452; GO:0005886; GO:0006814; GO:0008510; GO:0009986; GO:0015293; GO:0015701; GO:0016020; GO:0016323; GO:0022857; GO:0035725; GO:0036376; GO:0042391; GO:0042802; GO:0045821; GO:0050801; GO:0051453; GO:0055085; GO:0070062; GO:0150104 9039 FUN_034420 8998 6532 5140 9465 7970 ptg000024l:8725220-8739504 Q9Y6R1 1.72e-26 Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4) (kNBC1) Homo sapiens (Human) bicarbonate transport [GO:0015701]; ion homeostasis [GO:0050801]; positive regulation of glycolytic process [GO:0045821]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sodium ion export across plasma membrane [GO:0036376]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0005452; GO:0005886; GO:0006814; GO:0008510; GO:0009986; GO:0015293; GO:0015701; GO:0016020; GO:0016323; GO:0022857; GO:0035725; GO:0036376; GO:0042391; GO:0042802; GO:0045821; GO:0050801; GO:0051453; GO:0055085; GO:0070062; GO:0150104 9040 FUN_034423 1620 1060 653 1280 1426 NA NA NA NA NA NA NA 9041 FUN_034422 4060 2935 1940 3522 2868 ptg000024l:8750281-8772731 Q6DEU9 1.13e-45 RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000791; GO:0001711; GO:0006368; GO:0016593; GO:0016607; GO:0019827; GO:0045638; GO:0051571; GO:0080182; GO:2001162 9042 FUN_034422 4060 2935 1940 3522 2868 ptg000024l:8750281-8772731 Q6DEU9 2.05e-30 RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endodermal cell fate commitment [GO:0001711]; histone H3-K4 trimethylation [GO:0080182]; negative regulation of myeloid cell differentiation [GO:0045638]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K79 methylation [GO:2001162]; stem cell population maintenance [GO:0019827]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000122; GO:0000791; GO:0001711; GO:0006368; GO:0016593; GO:0016607; GO:0019827; GO:0045638; GO:0051571; GO:0080182; GO:2001162 9043 FUN_042873 1117 1162 435 1385 1017 NA NA NA NA NA NA NA 9044 FUN_042872 67 28 15 25 55 NA NA NA NA NA NA NA 9045 FUN_016711 32933 39952 20614 30838 17190 NA NA NA NA NA NA NA 9046 FUN_016717 298 377 325 333 176 NA NA NA NA NA NA NA 9047 FUN_016716 52 43 18 45 24 NA NA NA NA NA NA NA 9048 FUN_016715 188 184 81 173 164 NA NA NA NA NA NA NA 9049 FUN_042874 1250 496 548 511 795 ptg000047l:1177145-1185414 Q3MHZ7 7.11e-21 GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) Bos taurus (Bovine) attachment of GPI anchor to protein [GO:0016255]; proteolysis [GO:0006508] GO:0003923; GO:0006508; GO:0016255; GO:0042765 9050 FUN_042874 1250 496 548 511 795 ptg000047l:1177145-1185414 Q3MHZ7 7.11e-21 GPI-anchor transamidase (GPI transamidase) (EC 3.-.-.-) (Phosphatidylinositol-glycan biosynthesis class K protein) (PIG-K) Bos taurus (Bovine) attachment of GPI anchor to protein [GO:0016255]; proteolysis [GO:0006508] GO:0003923; GO:0006508; GO:0016255; GO:0042765 9051 FUN_016719 57 25 20 66 30 ptg000011l:6593035-6604563 P36898 5.04e-85 Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (Activin receptor-like kinase 6) (ALK-6) (Serine/threonine-protein kinase receptor R6) (SKR6) (CD antigen CDw293) Mus musculus (Mouse) BMP signaling pathway [GO:0030509]; bone development [GO:0060348]; camera-type eye development [GO:0043010]; cartilage condensation [GO:0001502]; cell differentiation [GO:0030154]; cellular response to BMP stimulus [GO:0071773]; cellular response to growth factor stimulus [GO:0071363]; central nervous system neuron differentiation [GO:0021953]; chondrocyte development [GO:0002063]; chondrocyte differentiation [GO:0002062]; dorsal/ventral pattern formation [GO:0009953]; endochondral bone morphogenesis [GO:0060350]; estrogen biosynthetic process [GO:0006703]; eye development [GO:0001654]; inflammatory response [GO:0006954]; negative regulation of chondrocyte proliferation [GO:1902731]; osteoblast differentiation [GO:0001649]; ovarian cumulus expansion [GO:0001550]; ovulation cycle [GO:0042698]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cartilage development [GO:0061036]; positive regulation of chondrocyte differentiation [GO:0032332]; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902043]; positive regulation of gene expression [GO:0010628]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein phosphorylation [GO:0006468]; proteoglycan biosynthetic process [GO:0030166]; retina development in camera-type eye [GO:0060041]; retinal ganglion cell axon guidance [GO:0031290]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] GO:0001502; GO:0001550; GO:0001649; GO:0001654; GO:0002062; GO:0002063; GO:0004674; GO:0004675; GO:0005024; GO:0005025; GO:0005524; GO:0005886; GO:0006468; GO:0006703; GO:0006954; GO:0007178; GO:0007179; GO:0009953; GO:0010628; GO:0019211; GO:0021953; GO:0030154; GO:0030166; GO:0030425; GO:0030501; GO:0030509; GO:0031290; GO:0032332; GO:0036122; GO:0042698; GO:0043010; GO:0043025; GO:0043235; GO:0043539; GO:0045669; GO:0045944; GO:0046332; GO:0046872; GO:0060041; GO:0060348; GO:0060350; GO:0061036; GO:0071363; GO:0071773; GO:0098821; GO:0140537; GO:1902043; GO:1902731 9052 FUN_040868 0 0 0 0 9 NA NA NA NA NA NA NA 9053 FUN_040869 0 0 0 0 16 NA NA NA NA NA NA NA 9054 FUN_040860 759 311 396 422 358 NA NA NA NA NA NA NA 9055 FUN_040861 5753 2694 4072 5085 5188 NA NA NA NA NA NA NA 9056 FUN_040866 1348 2162 533 1956 1366 ptg000031l:13641139-13655952 P24369 1.59e-24 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Mus musculus (Mouse) bone development [GO:0060348]; chaperone-mediated protein folding [GO:0061077]; neutrophil chemotaxis [GO:0030593]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation by host of viral process [GO:0044794]; positive regulation of multicellular organism growth [GO:0040018]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; protein stabilization [GO:0050821] GO:0000413; GO:0003755; GO:0005654; GO:0005737; GO:0005783; GO:0005788; GO:0005790; GO:0006457; GO:0016018; GO:0030593; GO:0032991; GO:0034663; GO:0040018; GO:0042470; GO:0043231; GO:0044794; GO:0044829; GO:0048471; GO:0050821; GO:0060348; GO:0061077; GO:0070063 9057 FUN_040867 67 430 155 225 80 NA NA NA NA NA NA NA 9058 FUN_002323 0 1 8 14 19 NA NA NA NA NA NA NA 9059 FUN_002322 2 14 106 92 242 NA NA NA NA NA NA NA 9060 FUN_002321 3 1 14 17 34 NA NA NA NA NA NA NA 9061 FUN_002320 7 16 75 77 347 NA NA NA NA NA NA NA 9062 FUN_002327 211 22 149 486 247 ntLink_8:40396-46759 Q96AY4 9.93e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9063 FUN_002327 211 22 149 486 247 ntLink_8:40396-46759 Q96AY4 1.08e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9064 FUN_002327 211 22 149 486 247 ntLink_8:40396-46759 Q96AY4 2.87e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9065 FUN_002327 211 22 149 486 247 ntLink_8:40396-46759 Q96AY4 7.07e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9066 FUN_002327 211 22 149 486 247 ntLink_8:40396-46759 Q96AY4 2.64e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9067 FUN_002327 211 22 149 486 247 ntLink_8:40396-46759 Q96AY4 5.14e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9068 FUN_002326 1 6 29 23 90 NA NA NA NA NA NA NA 9069 FUN_002325 3 4 20 53 95 NA NA NA NA NA NA NA 9070 FUN_011618 33 23 15 25 11 NA NA NA NA NA NA NA 9071 FUN_011617 7 0 52 0 121 ptg000007l:11819249-11822911 Q6LAF1 3.5e-46 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9072 FUN_011616 5 0 6 0 23 NA NA NA NA NA NA NA 9073 FUN_002329 700 58 96 335 268 ntLink_8:63466-69528 Q96AY4 3.23e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9074 FUN_002329 700 58 96 335 268 ntLink_8:63466-69528 Q96AY4 8.2e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9075 FUN_002329 700 58 96 335 268 ntLink_8:63466-69528 Q96AY4 5.8e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9076 FUN_002329 700 58 96 335 268 ntLink_8:63466-69528 Q96AY4 5.55e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9077 FUN_002329 700 58 96 335 268 ntLink_8:63466-69528 Q96AY4 1.22e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9078 FUN_002328 335 3 85 670 491 NA NA NA NA NA NA NA 9079 FUN_011612 0 0 0 0 7 NA NA NA NA NA NA NA 9080 FUN_012091 141 202 127 298 565 ptg000008l:5007435-5011651 Q95LU3 2.23e-61 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 9081 FUN_012092 326 452 55 132 4 ptg000008l:5021098-5024632 Q5DU56 2.18e-36 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9082 FUN_012093 94 24 33 21 0 NA NA NA NA NA NA NA 9083 FUN_012094 41 65 48 182 27 ptg000008l:5033082-5063749 D8VNS8 1.31e-61 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 9084 FUN_012094 41 65 48 182 27 ptg000008l:5033082-5063749 D8VNS8 2.1e-57 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 9085 FUN_012094 41 65 48 182 27 ptg000008l:5033082-5063749 D8VNS8 3.88e-56 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 9086 FUN_012094 41 65 48 182 27 ptg000008l:5033082-5063749 D8VNS8 7.11e-53 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 9087 FUN_012095 78 93 31 175 128 ptg000008l:5068122-5074224 Q95LU3 2.41e-62 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 9088 FUN_012096 202 143 0 199 51 ptg000008l:5076029-5080531 Q95LU3 4e-64 Fibrinogen C domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0008061; GO:0016020; GO:0046872 9089 FUN_012097 447 665 169 867 595 NA NA NA NA NA NA NA 9090 FUN_012098 37 15 6 0 52 NA NA NA NA NA NA NA 9091 FUN_012099 249 296 89 335 263 NA NA NA NA NA NA NA 9092 FUN_014557 2 0 3 0 9 NA NA NA NA NA NA NA 9093 FUN_014556 3760 3136 1911 2741 2597 NA NA NA NA NA NA NA 9094 FUN_014555 201 116 79 143 356 ptg000009l:1150989-1152816 Q8N3Y1 7.91e-21 F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29) Homo sapiens (Human) cell population proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription factor catabolic process [GO:1901485]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712] GO:0005794; GO:0005829; GO:0007030; GO:0008283; GO:0016567; GO:0019005; GO:0031467; GO:0048471; GO:0050775; GO:0060712; GO:0060716; GO:1901485 9095 FUN_014554 186 28 64 180 509 ptg000009l:1148019-1148562 P0DL28 7.16e-45 F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; Golgi organization [GO:0007030]; labyrinthine layer blood vessel development [GO:0060716]; positive regulation of dendrite morphogenesis [GO:0050775]; positive regulation of transcription factor catabolic process [GO:1901485]; protein ubiquitination [GO:0016567]; spongiotrophoblast layer development [GO:0060712] GO:0004842; GO:0005794; GO:0005829; GO:0007030; GO:0008283; GO:0016567; GO:0019005; GO:0031467; GO:0048471; GO:0050775; GO:0060712; GO:0060716; GO:1901485; GO:1990393 9096 FUN_014553 1407 1099 761 1167 767 ptg000009l:1132636-1135761 P29674 1.15e-84 LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (Xlim1) (x-Lhx1) (xLIM-1) Xenopus laevis (African clawed frog) anterior/posterior pattern specification [GO:0009952]; axis specification [GO:0009798]; cell migration involved in gastrulation [GO:0042074]; chordate embryonic development [GO:0043009]; muscle organ development [GO:0007517]; nephron tubule development [GO:0072080]; neurogenesis [GO:0022008]; notochord development [GO:0030903]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric field specification [GO:0039003]; pronephric nephron tubule development [GO:0039020]; pronephros development [GO:0048793]; regionalization [GO:0003002]; regulation of pronephros size [GO:0035565]; response to retinoic acid [GO:0032526] GO:0000981; GO:0001221; GO:0003002; GO:0005634; GO:0005667; GO:0007517; GO:0009798; GO:0009952; GO:0022008; GO:0030903; GO:0032526; GO:0035565; GO:0039003; GO:0039020; GO:0042074; GO:0043009; GO:0043565; GO:0045893; GO:0045944; GO:0046872; GO:0048793; GO:0072080 9097 FUN_014552 725 606 705 614 1197 ptg000009l:1120462-1128214 Q8R3C6 4.28e-77 Probable RNA-binding protein 19 (RNA-binding motif protein 19) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of embryonic development [GO:0040019] GO:0000398; GO:0003723; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0016607; GO:0040019 9098 FUN_014552 725 606 705 614 1197 ptg000009l:1120462-1128214 Q8R3C6 9.51e-22 Probable RNA-binding protein 19 (RNA-binding motif protein 19) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of embryonic development [GO:0040019] GO:0000398; GO:0003723; GO:0005654; GO:0005694; GO:0005730; GO:0005737; GO:0016607; GO:0040019 9099 FUN_014551 796 641 404 613 730 NA NA NA NA NA NA NA 9100 FUN_014550 384 198 208 218 442 ptg000009l:1115613-1118042 Q58728 7.97e-31 Uncharacterized GTP-binding protein MJ1332 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) NA GO:0005525; GO:0005737; GO:0016887 9101 FUN_014559 85919 108066 83631 80448 44331 NA NA NA NA NA NA NA 9102 FUN_014558 1626 1694 1104 1175 1369 NA NA NA NA NA NA NA 9103 FUN_009491 14 0 28 0 0 NA NA NA NA NA NA NA 9104 FUN_009492 46 0 2 0 0 NA NA NA NA NA NA NA 9105 FUN_009493 15 0 24 0 0 ptg000004l:7639093-7653776 P14381 2.24e-82 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 9106 FUN_009497 31 0 38 0 0 NA NA NA NA NA NA NA 9107 FUN_009498 24 3 14 0 0 NA NA NA NA NA NA NA 9108 FUN_022834 1520 1405 885 915 1257 NA NA NA NA NA NA NA 9109 FUN_022837 1544 1034 440 454 392 NA NA NA NA NA NA NA 9110 FUN_022830 3581 2574 1603 2619 1683 NA NA NA NA NA NA NA 9111 FUN_022833 4801 5601 2380 3106 2992 NA NA NA NA NA NA NA 9112 FUN_022832 25 70 70 99 165 ptg000017l:480172-482599 Q8WXB1 3.56e-51 Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A) Homo sapiens (Human) peptidyl-lysine methylation [GO:0018022]; protein methylation [GO:0006479] GO:0005654; GO:0005737; GO:0005829; GO:0006479; GO:0008276; GO:0016279; GO:0018022; GO:0018024; GO:0030544; GO:0031072; GO:0032991; GO:0051117 9113 FUN_026600 10 0 11 0 0 NA NA NA NA NA NA NA 9114 FUN_029779 0 0 0 24 0 NA NA NA NA NA NA NA 9115 FUN_029778 0 0 2 18 18 NA NA NA NA NA NA NA 9116 FUN_029776 0 15 0 23 8 NA NA NA NA NA NA NA 9117 FUN_029775 0 0 0 38 5 NA NA NA NA NA NA NA 9118 FUN_029774 27 0 32 73 48 NA NA NA NA NA NA NA 9119 FUN_029773 182 0 296 360 549 NA NA NA NA NA NA NA 9120 FUN_029772 254 399 331 511 543 NA NA NA NA NA NA NA 9121 FUN_029771 179 183 79 166 60 NA NA NA NA NA NA NA 9122 FUN_029770 431 327 251 569 585 NA NA NA NA NA NA NA 9123 FUN_016349 4600 2765 2315 3765 3521 NA NA NA NA NA NA NA 9124 FUN_016344 1252 1349 455 656 715 NA NA NA NA NA NA NA 9125 FUN_016345 1003 606 245 853 934 ptg000011l:1900622-1903380 P52189 5.53e-38 Inward rectifier potassium channel 4 (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4) Mus musculus (Mouse) potassium ion import across plasma membrane [GO:1990573]; regulation of ion transmembrane transport [GO:0034765] GO:0005242; GO:0005886; GO:0016323; GO:0030165; GO:0030425; GO:0030659; GO:0034765; GO:0043025; GO:0045211; GO:1990573 9126 FUN_016346 182 307 146 233 235 ptg000011l:1919277-1920441 Q6NW96 1.69e-80 Transcription factor Sp9 Danio rerio (Zebrafish) (Brachydanio rerio) embryonic limb morphogenesis [GO:0030326]; embryonic pectoral fin morphogenesis [GO:0035118]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0030326; GO:0035118; GO:0045743; GO:0046872 9127 FUN_016347 332 150 139 307 341 ptg000011l:1946283-1947626 Q6BEB4 2.01e-58 Transcription factor Sp5 Homo sapiens (Human) bone morphogenesis [GO:0060349]; cellular response to organic cyclic compound [GO:0071407]; post-anal tail morphogenesis [GO:0036342]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0036342; GO:0046872; GO:0060349; GO:0071407 9128 FUN_016340 3549 1866 2326 3950 1877 NA NA NA NA NA NA NA 9129 FUN_016341 3101 2449 2091 1860 959 NA NA NA NA NA NA NA 9130 FUN_016342 1591 1022 769 1175 1608 NA NA NA NA NA NA NA 9131 FUN_016343 839 1239 578 632 819 ptg000011l:1886173-1889539 Q8JGT5 2.89e-25 SUMO-activating enzyme subunit 1 (SUMO-activating enzyme E1 N subunit) (Ubiquitin-like 1-activating enzyme E1A) Xenopus laevis (African clawed frog) protein sumoylation [GO:0016925] GO:0008641; GO:0016925; GO:0031510 9132 FUN_010802 1302 810 1130 2316 1677 NA NA NA NA NA NA NA 9133 FUN_015607 117 0 34 10 3 NA NA NA NA NA NA NA 9134 FUN_028798 25 25 0 3 0 NA NA NA NA NA NA NA 9135 FUN_028799 120 64 109 112 0 NA NA NA NA NA NA NA 9136 FUN_026338 33 0 0 0 0 NA NA NA NA NA NA NA 9137 FUN_026339 33 0 4 3 0 NA NA NA NA NA NA NA 9138 FUN_026336 26 0 0 0 0 NA NA NA NA NA NA NA 9139 FUN_026337 46 0 4 0 0 NA NA NA NA NA NA NA 9140 FUN_026334 29 0 4 0 0 NA NA NA NA NA NA NA 9141 FUN_028791 0 0 3 0 17 NA NA NA NA NA NA NA 9142 FUN_026332 33 0 5 0 0 NA NA NA NA NA NA NA 9143 FUN_026333 37 0 2 0 0 NA NA NA NA NA NA NA 9144 FUN_028794 1170 203 213 227 190 NA NA NA NA NA NA NA 9145 FUN_026331 34 0 3 0 0 NA NA NA NA NA NA NA 9146 FUN_025689 1740 2037 663 1177 994 ptg000019l:5741234-5754809 P58058 6.46e-26 NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) Mus musculus (Mouse) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003951; GO:0005524; GO:0005829; GO:0006741; GO:0016310; GO:0019674; GO:0035774; GO:0046872 9147 FUN_025689 1740 2037 663 1177 994 ptg000019l:5741234-5754809 P58058 6.46e-26 NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase) Mus musculus (Mouse) NAD metabolic process [GO:0019674]; NADP biosynthetic process [GO:0006741]; phosphorylation [GO:0016310]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774] GO:0003951; GO:0005524; GO:0005829; GO:0006741; GO:0016310; GO:0019674; GO:0035774; GO:0046872 9148 FUN_025688 140 173 146 48 88 NA NA NA NA NA NA NA 9149 FUN_025687 997 1182 282 658 755 NA NA NA NA NA NA NA 9150 FUN_025686 1131 1227 580 1121 1182 NA NA NA NA NA NA NA 9151 FUN_025685 13121 19682 13312 13292 8017 NA NA NA NA NA NA NA 9152 FUN_025684 800 1044 422 752 714 NA NA NA NA NA NA NA 9153 FUN_025683 60 69 12 135 81 NA NA NA NA NA NA NA 9154 FUN_025682 206 119 254 158 416 ptg000019l:5664764-5674128 Q3UQ28 1.04e-86 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 9155 FUN_025681 6142 2855 2982 6912 5139 ptg000019l:5649140-5663105 P98064 3.44e-33 Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508] GO:0001867; GO:0002752; GO:0004252; GO:0005509; GO:0005615; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0042802; GO:0042803; GO:0045916; GO:0048306; GO:1903028; GO:1905370 9156 FUN_025681 6142 2855 2982 6912 5139 ptg000019l:5649140-5663105 P98064 3.44e-33 Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; negative regulation of complement activation [GO:0045916]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508] GO:0001867; GO:0002752; GO:0004252; GO:0005509; GO:0005615; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0042802; GO:0042803; GO:0045916; GO:0048306; GO:1903028; GO:1905370 9157 FUN_025680 83 66 17 39 62 ptg000019l:5644931-5647121 P47793 6.18e-66 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 9158 FUN_025680 83 66 17 39 62 ptg000019l:5644931-5647121 P47793 1.8e-25 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 9159 FUN_017769 5056 1667 300 2394 2047 NA NA NA NA NA NA NA 9160 FUN_017768 5340 5126 2524 4504 2803 ptg000012l:242012-247479 Q3ZBD0 2.47e-47 26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005838; GO:0008237; GO:0043161 9161 FUN_017765 2218 1011 984 1974 1370 ptg000012l:196325-206187 A0A096X8J7 6.9e-39 NA NA NA NA 9162 FUN_017765 2218 1011 984 1974 1370 ptg000012l:196325-206187 A0A096X8J7 6.65e-27 NA NA NA NA 9163 FUN_017764 125 91 198 83 203 ptg000012l:188246-190064 Q08DF7 1.12e-140 2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4) Bos taurus (Bovine) cellular response to dsRNA [GO:0071359]; cellular response to interferon-alpha [GO:0035457]; cellular response to type II interferon [GO:0071346]; mitochondrial mRNA catabolic process [GO:0000958]; mRNA processing [GO:0006397]; negative regulation of cell death [GO:0060548]; negative regulation of oxidative phosphorylation [GO:0090324]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of viral genome replication [GO:0045070]; regulation of mitochondrial mRNA stability [GO:0044528] GO:0000175; GO:0000288; GO:0000958; GO:0004527; GO:0004535; GO:0005739; GO:0005759; GO:0006397; GO:0035457; GO:0044528; GO:0045070; GO:0046872; GO:0060548; GO:0071346; GO:0071359; GO:0090324 9164 FUN_017767 1428 1350 489 693 1271 NA NA NA NA NA NA NA 9165 FUN_017766 3978 3018 1696 2989 2172 NA NA NA NA NA NA NA 9166 FUN_017761 2773 2178 1285 1406 1215 ptg000012l:159664-168235 P20825 1.15e-91 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 9167 FUN_017760 12719 10375 7897 13708 10746 NA NA NA NA NA NA NA 9168 FUN_017763 0 32 6 20 35 NA NA NA NA NA NA NA 9169 FUN_017762 4006 2910 2403 5425 3880 NA NA NA NA NA NA NA 9170 FUN_042305 0 0 0 0 11 NA NA NA NA NA NA NA 9171 FUN_016064 430 282 890 343 446 NA NA NA NA NA NA NA 9172 FUN_016067 28 51 92 110 18 NA NA NA NA NA NA NA 9173 FUN_026480 20 24 23 16 64 ptg000020l:9415092-9416562 Q6DIV6 1.89e-54 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 9174 FUN_026481 323 88 123 174 134 ptg000020l:9421176-9422622 Q6DIV6 3.76e-59 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 9175 FUN_026482 151 57 44 132 85 ptg000020l:9423854-9425360 Q6DIV6 3.96e-76 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 9176 FUN_026483 35 30 20 62 14 ptg000020l:9431041-9432727 Q6DIV6 7.24e-52 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 9177 FUN_026484 625 470 346 387 279 NA NA NA NA NA NA NA 9178 FUN_026485 5872 2716 3245 2545 2638 NA NA NA NA NA NA NA 9179 FUN_026486 7641 7648 6121 5792 2956 NA NA NA NA NA NA NA 9180 FUN_026487 18916 28014 10165 10764 11007 ptg000020l:9486247-9486763 Q5RBA4 1.42e-81 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005509; GO:0005938; GO:0016459 9181 FUN_026488 3708 1715 1687 3663 1360 NA NA NA NA NA NA NA 9182 FUN_026489 5285 10375 4064 2363 3558 NA NA NA NA NA NA NA 9183 FUN_028422 5 3 8 22 7 NA NA NA NA NA NA NA 9184 FUN_022303 242 102 47 0 0 NA NA NA NA NA NA NA 9185 FUN_022302 238 260 382 288 189 NA NA NA NA NA NA NA 9186 FUN_022301 1143 662 344 61 163 NA NA NA NA NA NA NA 9187 FUN_022307 1604 1764 698 1186 717 NA NA NA NA NA NA NA 9188 FUN_022306 11 2 13 74 29 NA NA NA NA NA NA NA 9189 FUN_022305 435 296 30 131 49 NA NA NA NA NA NA NA 9190 FUN_010659 105062 229670 129680 139006 87241 NA NA NA NA NA NA NA 9191 FUN_022309 4830 3905 3100 4043 3456 ptg000016l:7422828-7429240 Q29RV1 7.67e-48 Protein disulfide-isomerase A4 (EC 5.3.4.1) Bos taurus (Bovine) NA GO:0003756; GO:0005788; GO:0042470 9192 FUN_022309 4830 3905 3100 4043 3456 ptg000016l:7422828-7429240 Q29RV1 4.07e-21 Protein disulfide-isomerase A4 (EC 5.3.4.1) Bos taurus (Bovine) NA GO:0003756; GO:0005788; GO:0042470 9193 FUN_022308 35631 24011 19182 28338 17511 NA NA NA NA NA NA NA 9194 FUN_016068 452 309 306 550 266 NA NA NA NA NA NA NA 9195 FUN_028343 0 4 0 164 0 NA NA NA NA NA NA NA 9196 FUN_010653 23 0 0 8 123 NA NA NA NA NA NA NA 9197 FUN_008076 634447 585705 362834 658538 669740 NA NA NA NA NA NA NA 9198 FUN_028347 0 12 11 22 19 NA NA NA NA NA NA NA 9199 FUN_028346 0 0 0 512 0 NA NA NA NA NA NA NA 9200 FUN_044152 3 3 7 18 24 NA NA NA NA NA NA NA 9201 FUN_014233 74 0 54 0 0 NA NA NA NA NA NA NA 9202 FUN_014230 68 29 4 70 10 NA NA NA NA NA NA NA 9203 FUN_014231 0 0 7 0 0 NA NA NA NA NA NA NA 9204 FUN_044157 6 10 51 58 180 NA NA NA NA NA NA NA 9205 FUN_014234 0 0 0 34 0 NA NA NA NA NA NA NA 9206 FUN_044155 2 2 10 12 25 NA NA NA NA NA NA NA 9207 FUN_019609 194 15 72 205 9 NA NA NA NA NA NA NA 9208 FUN_014238 16 11 0 10 5 NA NA NA NA NA NA NA 9209 FUN_014239 2 9 0 12 18 NA NA NA NA NA NA NA 9210 FUN_024226 114 169 41 126 56 ptg000018l:3682607-3685947 Q8K3Z0 2.61e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 9211 FUN_024224 3661 1657 1494 2707 2111 ptg000018l:3638950-3656166 Q8BYJ6 2.55e-29 TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; cellular response to insulin stimulus [GO:0032869]; negative regulation of vesicle fusion [GO:0031339]; vesicle-mediated transport [GO:0016192] GO:0005096; GO:0005829; GO:0016192; GO:0030659; GO:0031339; GO:0031982; GO:0032869; GO:0090630 9212 FUN_024225 70 226 486 570 212 NA NA NA NA NA NA NA 9213 FUN_024222 26272 7973 5082 6969 3690 ptg000018l:3609652-3611183 Q13887 4.73e-53 Krueppel-like factor 5 (Basic transcription element-binding protein 2) (BTE-binding protein 2) (Colon krueppel-like factor) (GC-box-binding protein 2) (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) Homo sapiens (Human) angiogenesis [GO:0001525]; cell-cell signaling via exosome [GO:0099156]; cellular response to leukemia inhibitory factor [GO:1990830]; intestinal epithelial cell development [GO:0060576]; microvillus assembly [GO:0030033]; myotube differentiation involved in skeletal muscle regeneration [GO:0014908]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by transcription factor localization [GO:0061586]; regulation of microvillus assembly [GO:0032534]; regulation of transcription by RNA polymerase II [GO:0006357]; satellite cell activation involved in skeletal muscle regeneration [GO:0014901]; skeletal muscle satellite cell differentiation [GO:0014816] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001525; GO:0005654; GO:0005667; GO:0005794; GO:0006357; GO:0014816; GO:0014901; GO:0014908; GO:0030033; GO:0032534; GO:0043231; GO:0043426; GO:0045600; GO:0045944; GO:0046872; GO:0060576; GO:0061586; GO:0099156; GO:1902895; GO:1990830; GO:1990837 9214 FUN_024223 8558 8447 4583 7474 4649 NA NA NA NA NA NA NA 9215 FUN_024220 2419 2166 839 1727 1368 ptg000018l:3587542-3594669 O75840 4.21e-46 Krueppel-like factor 7 (Ubiquitous krueppel-like factor) Homo sapiens (Human) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; dendrite morphogenesis [GO:0048813]; glucose homeostasis [GO:0042593]; negative regulation of adipose tissue development [GO:1904178]; negative regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061179]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epidermal cell differentiation [GO:0045604]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0007409; GO:0007411; GO:0008270; GO:0042593; GO:0045604; GO:0045944; GO:0048813; GO:0061179; GO:1904178 9216 FUN_024221 22 16 0 0 0 NA NA NA NA NA NA NA 9217 FUN_024228 0 90 118 130 79 NA NA NA NA NA NA NA 9218 FUN_024229 24 64 39 83 9 NA NA NA NA NA NA NA 9219 FUN_030135 18 0 0 0 19 NA NA NA NA NA NA NA 9220 FUN_030134 0 0 0 0 46 NA NA NA NA NA NA NA 9221 FUN_030133 0 0 0 0 47 NA NA NA NA NA NA NA 9222 FUN_030132 0 0 60 0 140 NA NA NA NA NA NA NA 9223 FUN_018206 61 29 36 98 30 NA NA NA NA NA NA NA 9224 FUN_037231 459 469 425 569 744 ptg000026l:7335150-7336050 Q920M9 1.48e-172 E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a) Rattus norvegicus (Rat) canonical Wnt signaling pathway [GO:0060070]; cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; post-embryonic development [GO:0009791]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein catabolic process [GO:0030163]; protein destabilization [GO:0031648]; regulation of multicellular organism growth [GO:0040014]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005634; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006511; GO:0007141; GO:0007283; GO:0008022; GO:0008270; GO:0009791; GO:0019005; GO:0030154; GO:0030163; GO:0030877; GO:0031624; GO:0031648; GO:0040014; GO:0042802; GO:0042803; GO:0043065; GO:0043161; GO:0051402; GO:0060070; GO:0061630; GO:0097718; GO:2001244 9225 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 4.67e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9226 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 1.73e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9227 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 6.44e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9228 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 1.25e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9229 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 2.28e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9230 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 1.53e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9231 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 1.45e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9232 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 1.48e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9233 FUN_018202 320 469 206 101 331 ptg000012l:5869883-5884042 Q96AY4 5e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9234 FUN_032348 4702 4059 2550 3392 3181 NA NA NA NA NA NA NA 9235 FUN_015183 1421 1301 915 2347 1989 ptg000009l:7165968-7181771 A0A0R4IZ84 9.95e-27 Telomerase-binding protein EST1A (EC 3.1.-.-) (Ever shorter telomeres 1A) (Nonsense mediated mRNA decay factor SMG6) (Smg-6 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184] GO:0000184; GO:0000781; GO:0004519; GO:0005697; GO:0005730; GO:0005829; GO:0042162; GO:0043009; GO:0070034 9236 FUN_035400 11 0 0 0 14 NA NA NA NA NA NA NA 9237 FUN_015181 13 0 0 19 21 NA NA NA NA NA NA NA 9238 FUN_015180 0 0 0 35 0 NA NA NA NA NA NA NA 9239 FUN_015187 914 441 461 445 427 NA NA NA NA NA NA NA 9240 FUN_015186 1006 705 377 582 421 NA NA NA NA NA NA NA 9241 FUN_015185 242 514 299 231 263 NA NA NA NA NA NA NA 9242 FUN_030433 11 0 8 0 40 ptg000023l:10858116-10858879 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9243 FUN_015189 594 323 475 585 326 NA NA NA NA NA NA NA 9244 FUN_015188 2 14 27 62 55 NA NA NA NA NA NA NA 9245 FUN_035402 753 442 256 651 223 ptg000025l:7072246-7074718 Q11126 7.94e-43 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 9246 FUN_030431 8 0 10 0 43 ptg000023l:10854064-10854827 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9247 FUN_035404 2034 766 1048 1294 1121 NA NA NA NA NA NA NA 9248 FUN_030437 9 0 9 0 38 ptg000023l:10866220-10866983 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9249 FUN_032342 2785 3725 1958 4158 2800 NA NA NA NA NA NA NA 9250 FUN_032343 4531 9275 2862 8772 7547 NA NA NA NA NA NA NA 9251 FUN_035407 32 33 17 43 0 NA NA NA NA NA NA NA 9252 FUN_023948 2335 2420 795 1896 1882 NA NA NA NA NA NA NA 9253 FUN_032341 144 15 69 44 0 NA NA NA NA NA NA NA 9254 FUN_023942 146 95 179 39 53 ptg000018l:387128-388953 O15091 6.61e-24 Mitochondrial ribonuclease P catalytic subunit (EC 3.1.26.5) (Mitochondrial ribonuclease P protein 3) (Mitochondrial RNase P protein 3) (Protein only RNase P catalytic subunit) Homo sapiens (Human) mitochondrial tRNA 5'-end processing [GO:0097745]; tRNA 5'-leader removal [GO:0001682] GO:0001682; GO:0004526; GO:0005654; GO:0005739; GO:0005759; GO:0030678; GO:0042645; GO:0046872; GO:0097745 9255 FUN_023943 5338 2584 839 4852 4939 NA NA NA NA NA NA NA 9256 FUN_023940 0 0 10 0 9 NA NA NA NA NA NA NA 9257 FUN_023941 119 118 81 139 175 NA NA NA NA NA NA NA 9258 FUN_023946 3322 1697 1373 2075 1365 NA NA NA NA NA NA NA 9259 FUN_023947 2889 2227 1366 2301 1707 NA NA NA NA NA NA NA 9260 FUN_023945 962 931 843 817 434 ptg000018l:401519-404056 Q7PXY4 4.23e-22 Histone deacetylase complex subunit SAP30 homolog Anopheles gambiae (African malaria mosquito) regulation of DNA-templated transcription [GO:0006355] GO:0000118; GO:0003677; GO:0003712; GO:0006355; GO:0046872 9261 FUN_023945 962 931 843 817 434 ptg000018l:401519-404056 Q7PXY4 4.23e-22 Histone deacetylase complex subunit SAP30 homolog Anopheles gambiae (African malaria mosquito) regulation of DNA-templated transcription [GO:0006355] GO:0000118; GO:0003677; GO:0003712; GO:0006355; GO:0046872 9262 FUN_031664 260 66 229 966 1216 ptg000023l:24157003-24172428 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9263 FUN_031664 260 66 229 966 1216 ptg000023l:24157003-24172428 Q9NZJ4 4.54e-59 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9264 FUN_031664 260 66 229 966 1216 ptg000023l:24157003-24172428 Q9NZJ4 8.7e-46 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9265 FUN_031664 260 66 229 966 1216 ptg000023l:24157003-24172428 Q9NZJ4 6.05e-23 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9266 FUN_031665 1094 815 463 966 850 ptg000023l:24178119-24202898 P21328 5.94e-26 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 9267 FUN_039419 12 0 4 0 55 NA NA NA NA NA NA NA 9268 FUN_039418 131 12 0 168 0 NA NA NA NA NA NA NA 9269 FUN_031660 636 241 513 2175 1150 ptg000023l:24095756-24111774 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9270 FUN_031660 636 241 513 2175 1150 ptg000023l:24095756-24111774 Q9NZJ4 4.07e-56 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9271 FUN_031660 636 241 513 2175 1150 ptg000023l:24095756-24111774 Q9NZJ4 7.83e-53 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9272 FUN_031660 636 241 513 2175 1150 ptg000023l:24095756-24111774 Q9NZJ4 1.18e-22 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9273 FUN_031661 1584 708 913 1469 629 ptg000023l:24117273-24136462 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9274 FUN_031661 1584 708 913 1469 629 ptg000023l:24117273-24136462 Q9NZJ4 4.19e-62 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9275 FUN_031661 1584 708 913 1469 629 ptg000023l:24117273-24136462 Q9NZJ4 2.35e-58 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9276 FUN_031661 1584 708 913 1469 629 ptg000023l:24117273-24136462 Q9NZJ4 2.76e-22 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 9277 FUN_031662 13 7 0 11 27 NA NA NA NA NA NA NA 9278 FUN_039412 0 45 0 0 11 NA NA NA NA NA NA NA 9279 FUN_039411 0 30 0 0 0 NA NA NA NA NA NA NA 9280 FUN_031668 383 203 117 466 422 NA NA NA NA NA NA NA 9281 FUN_031669 5834 3450 2426 6027 6515 NA NA NA NA NA NA NA 9282 FUN_039415 734 146 80 729 80 NA NA NA NA NA NA NA 9283 FUN_039414 199 14 76 83 50 NA NA NA NA NA NA NA 9284 FUN_004921 42 72 71 15 168 ntLink_8:28775003-28780971 Q9BS34 2.1e-28 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 9285 FUN_004921 42 72 71 15 168 ntLink_8:28775003-28780971 Q9BS34 3.97e-27 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 9286 FUN_004921 42 72 71 15 168 ntLink_8:28775003-28780971 Q9BS34 2.49e-24 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 9287 FUN_004921 42 72 71 15 168 ntLink_8:28775003-28780971 Q9BS34 2.73e-24 Zinc finger protein 670 Homo sapiens (Human) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0006629; GO:0044255; GO:0046872 9288 FUN_004920 3591 1767 1586 3393 3782 NA NA NA NA NA NA NA 9289 FUN_026892 6 0 0 0 0 NA NA NA NA NA NA NA 9290 FUN_004927 39 0 42 72 58 ntLink_8:28884660-28887647 O42358 4.54e-22 Retinal homeobox protein Rx3 Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; camera-type eye morphogenesis [GO:0048593]; cell fate specification [GO:0001708]; embryonic camera-type eye morphogenesis [GO:0048596]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; hypothalamus development [GO:0021854]; neural crest cell migration [GO:0001755]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000978; GO:0000981; GO:0001654; GO:0001708; GO:0001755; GO:0005634; GO:0006357; GO:0021854; GO:0021984; GO:0030900; GO:0045944; GO:0048593; GO:0048596; GO:0060041; GO:0060898 9291 FUN_038604 0 0 0 59 17 NA NA NA NA NA NA NA 9292 FUN_004925 443 296 228 160 103 NA NA NA NA NA NA NA 9293 FUN_007946 432 244 231 101 3 ptg000002l:6429594-6431867 P36410 6.26e-33 Ras-related protein Rab-14 (Rab4-like GTPase) Dictyostelium discoideum (Social amoeba) contractile vacuole organization [GO:0033298]; defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; phagolysosome assembly involved in apoptotic cell clearance [GO:0090387]; regulation of endosomal vesicle fusion [GO:1905364]; regulation of pinocytosis [GO:0048548]; response to osmotic stress [GO:0006970] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005769; GO:0005802; GO:0005811; GO:0005829; GO:0006886; GO:0006895; GO:0006970; GO:0012505; GO:0031164; GO:0032456; GO:0033298; GO:0042742; GO:0045335; GO:0048548; GO:0055037; GO:0062160; GO:0090387; GO:0140220; GO:1905364 9294 FUN_038606 38 8 0 80 4 NA NA NA NA NA NA NA 9295 FUN_023604 182 275 107 49 59 ptg000017l:9806451-9811941 Q96AY4 7.12e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9296 FUN_023604 182 275 107 49 59 ptg000017l:9806451-9811941 Q96AY4 1.12e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9297 FUN_023604 182 275 107 49 59 ptg000017l:9806451-9811941 Q96AY4 7.12e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9298 FUN_023604 182 275 107 49 59 ptg000017l:9806451-9811941 Q96AY4 1.1e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9299 FUN_023604 182 275 107 49 59 ptg000017l:9806451-9811941 Q96AY4 1.09e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9300 FUN_023604 182 275 107 49 59 ptg000017l:9806451-9811941 Q96AY4 4.37e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9301 FUN_026894 0 0 0 0 37 NA NA NA NA NA NA NA 9302 FUN_026819 122 79 115 191 97 NA NA NA NA NA NA NA 9303 FUN_026818 49 23 37 36 75 NA NA NA NA NA NA NA 9304 FUN_023608 140 175 155 73 56 ptg000017l:9883938-9889734 Q96AY4 1.76e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9305 FUN_023608 140 175 155 73 56 ptg000017l:9883938-9889734 Q96AY4 7.37e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9306 FUN_023608 140 175 155 73 56 ptg000017l:9883938-9889734 Q96AY4 1.15e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9307 FUN_023608 140 175 155 73 56 ptg000017l:9883938-9889734 Q96AY4 1.92e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9308 FUN_023608 140 175 155 73 56 ptg000017l:9883938-9889734 Q96AY4 1.92e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9309 FUN_026813 3 15 0 0 7 NA NA NA NA NA NA NA 9310 FUN_026812 2 4 0 79 98 NA NA NA NA NA NA NA 9311 FUN_026811 0 0 7 0 0 NA NA NA NA NA NA NA 9312 FUN_026814 0 0 0 0 14 NA NA NA NA NA NA NA 9313 FUN_015077 68 105 73 90 65 NA NA NA NA NA NA NA 9314 FUN_015076 809 864 451 913 1136 ptg000009l:5919622-5921325 Q11126 1.41e-45 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 9315 FUN_028934 394 323 147 446 356 NA NA NA NA NA NA NA 9316 FUN_037549 9 1 4 27 6 NA NA NA NA NA NA NA 9317 FUN_015074 410 68 213 129 103 ptg000009l:5883067-5887154 Q11126 1.73e-40 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 9318 FUN_015074 410 68 213 129 103 ptg000009l:5883067-5887154 Q11126 2.23e-38 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 9319 FUN_037543 0 7 0 0 0 NA NA NA NA NA NA NA 9320 FUN_015073 1 36 55 48 40 NA NA NA NA NA NA NA 9321 FUN_037547 1267 2826 980 2466 946 NA NA NA NA NA NA NA 9322 FUN_037546 286 75 17 318 368 ptg000026l:11641668-11642409 O74549 4.53e-23 NEDD8-conjugating enzyme ubc12 (EC 2.3.2.34) (RUB1-conjugating enzyme) (Ubiquitin carrier protein 12) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) protein neddylation [GO:0045116] GO:0005524; GO:0005634; GO:0005829; GO:0019788; GO:0045116; GO:0061654 9323 FUN_037545 12297 10429 6174 27527 13843 NA NA NA NA NA NA NA 9324 FUN_015072 112 57 230 32 32 ptg000009l:5866627-5867809 Q11126 1.06e-44 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 9325 FUN_015071 1443 584 1122 1477 1147 NA NA NA NA NA NA NA 9326 FUN_015070 4370 6302 3754 3207 1638 NA NA NA NA NA NA NA 9327 FUN_040327 2488 1955 1760 1292 1612 NA NA NA NA NA NA NA 9328 FUN_028938 710 1194 1536 557 584 NA NA NA NA NA NA NA 9329 FUN_028939 173 237 322 217 184 NA NA NA NA NA NA NA 9330 FUN_005559 19 153 131 13 14 NA NA NA NA NA NA NA 9331 FUN_001249 9 12 80 90 46 NA NA NA NA NA NA NA 9332 FUN_001248 79 10 34 67 13 NA NA NA NA NA NA NA 9333 FUN_001245 659 466 265 508 517 NA NA NA NA NA NA NA 9334 FUN_001244 1660 1040 671 1287 1034 NA NA NA NA NA NA NA 9335 FUN_001247 540 301 607 526 464 NA NA NA NA NA NA NA 9336 FUN_001246 1724 2029 1221 1482 1157 NA NA NA NA NA NA NA 9337 FUN_001241 532 380 471 349 213 ntLink_6:10212858-10219897 A2BHJ4 8.36e-49 CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; RNA-mediated gene silencing [GO:0031047] GO:0000175; GO:0000289; GO:0004535; GO:0005634; GO:0005737; GO:0006397; GO:0030014; GO:0031047; GO:0046872 9338 FUN_001241 532 380 471 349 213 ntLink_6:10212858-10219897 A2BHJ4 2.51e-31 CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; RNA-mediated gene silencing [GO:0031047] GO:0000175; GO:0000289; GO:0004535; GO:0005634; GO:0005737; GO:0006397; GO:0030014; GO:0031047; GO:0046872 9339 FUN_001241 532 380 471 349 213 ntLink_6:10212858-10219897 A2BHJ4 2.52e-22 CCR4-NOT transcription complex subunit 6-like (EC 3.1.13.4) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; RNA-mediated gene silencing [GO:0031047] GO:0000175; GO:0000289; GO:0004535; GO:0005634; GO:0005737; GO:0006397; GO:0030014; GO:0031047; GO:0046872 9340 FUN_001240 480 495 269 545 324 NA NA NA NA NA NA NA 9341 FUN_001243 52 85 7 18 42 NA NA NA NA NA NA NA 9342 FUN_001242 0 0 5 6 24 NA NA NA NA NA NA NA 9343 FUN_034169 154 0 0 229 335 NA NA NA NA NA NA NA 9344 FUN_026605 20 0 0 0 6 NA NA NA NA NA NA NA 9345 FUN_025892 3 3 3 0 13 NA NA NA NA NA NA NA 9346 FUN_025893 0 103 0 0 0 NA NA NA NA NA NA NA 9347 FUN_025890 64 4 9 0 16 NA NA NA NA NA NA NA 9348 FUN_025891 40 0 18 0 0 NA NA NA NA NA NA NA 9349 FUN_025896 0 7 0 0 0 NA NA NA NA NA NA NA 9350 FUN_025897 41 61 0 0 52 ptg000020l:1702201-1705526 Q8BHB0 1.26e-27 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 9351 FUN_025895 23 121 73 0 30 NA NA NA NA NA NA NA 9352 FUN_025899 185 179 192 20 114 NA NA NA NA NA NA NA 9353 FUN_004202 5367 3291 2945 8144 5031 NA NA NA NA NA NA NA 9354 FUN_004203 685 719 567 626 756 NA NA NA NA NA NA NA 9355 FUN_004200 2518 3093 1712 2173 1603 NA NA NA NA NA NA NA 9356 FUN_004201 527 177 211 224 210 NA NA NA NA NA NA NA 9357 FUN_004206 1202 938 533 827 692 ntLink_8:20773007-20773760 F4INN2 1.3e-26 Gamma-glutamyl peptidase 4 (EC 3.4.19.-) Arabidopsis thaliana (Mouse-ear cress) proteolysis [GO:0006508] GO:0005829; GO:0006508; GO:0008233 9358 FUN_004207 707 627 407 851 688 ntLink_8:20776918-20778311 Q28FX0 3.63e-91 ELAV-like protein 3 (Protein ElrC) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0007399; GO:0030154; GO:1990904 9359 FUN_004204 7721 6718 5014 3966 4138 NA NA NA NA NA NA NA 9360 FUN_004205 24866 25939 16904 22699 15203 NA NA NA NA NA NA NA 9361 FUN_004208 1476 951 493 989 738 ntLink_8:20786057-20788587 P51688 4.01e-126 N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) Homo sapiens (Human) glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0005539; GO:0005764; GO:0006027; GO:0008484; GO:0016250; GO:0030200; GO:0043202; GO:0046872; GO:0070062 9362 FUN_004208 1476 951 493 989 738 ntLink_8:20786057-20788587 P51688 5.18e-22 N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) Homo sapiens (Human) glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0005539; GO:0005764; GO:0006027; GO:0008484; GO:0016250; GO:0030200; GO:0043202; GO:0046872; GO:0070062 9363 FUN_004208 1476 951 493 989 738 ntLink_8:20786057-20788587 P51688 4.13e-21 N-sulphoglucosamine sulphohydrolase (EC 3.10.1.1) (Sulfoglucosamine sulfamidase) (Sulphamidase) Homo sapiens (Human) glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0005539; GO:0005764; GO:0006027; GO:0008484; GO:0016250; GO:0030200; GO:0043202; GO:0046872; GO:0070062 9364 FUN_004209 1133 1463 821 915 1526 ntLink_8:20789480-20792880 A7SN31 5.47e-41 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase) Nematostella vectensis (Starlet sea anemone) L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166] GO:0005634; GO:0005829; GO:0006166; GO:0017061; GO:0019509 9365 FUN_004209 1133 1463 821 915 1526 ntLink_8:20789480-20792880 A7SN31 2.19e-32 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase) Nematostella vectensis (Starlet sea anemone) L-methionine salvage from methylthioadenosine [GO:0019509]; purine ribonucleoside salvage [GO:0006166] GO:0005634; GO:0005829; GO:0006166; GO:0017061; GO:0019509 9366 FUN_018219 169 237 97 124 109 NA NA NA NA NA NA NA 9367 FUN_018210 0 0 5 0 44 NA NA NA NA NA NA NA 9368 FUN_018211 127 69 98 352 200 NA NA NA NA NA NA NA 9369 FUN_018212 57 19 0 289 77 NA NA NA NA NA NA NA 9370 FUN_018214 185 0 34 93 0 NA NA NA NA NA NA NA 9371 FUN_018215 84 0 0 2 0 NA NA NA NA NA NA NA 9372 FUN_018216 18 24 19 25 20 NA NA NA NA NA NA NA 9373 FUN_018217 142827 168 151 826 2783 NA NA NA NA NA NA NA 9374 FUN_007957 599 410 598 566 637 ptg000002l:6539397-6541457 P25703 1.54e-65 Bone morphogenetic protein 2-A (BMP-2-I) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503] GO:0001503; GO:0005125; GO:0005615; GO:0008083; GO:0030154; GO:0051216 9375 FUN_007956 5 1 0 25 23 NA NA NA NA NA NA NA 9376 FUN_007955 2435 1178 683 1611 1459 NA NA NA NA NA NA NA 9377 FUN_007953 3514 2413 1934 2182 1150 NA NA NA NA NA NA NA 9378 FUN_007952 114 0 95 5 0 NA NA NA NA NA NA NA 9379 FUN_007951 36863 43334 28068 16050 21548 NA NA NA NA NA NA NA 9380 FUN_007950 765 893 418 483 521 NA NA NA NA NA NA NA 9381 FUN_007959 120 224 230 75 16 NA NA NA NA NA NA NA 9382 FUN_007958 0 12 0 16 15 NA NA NA NA NA NA NA 9383 FUN_034159 2922 2847 1967 2546 2123 ptg000024l:5551459-5568374 Q8CFE4 1.51e-22 SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa) Mus musculus (Mouse) brain development [GO:0007420]; endosome to lysosome transport [GO:0008333]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; positive regulation of clathrin-dependent endocytosis [GO:2000370]; positive regulation of receptor internalization [GO:0002092]; protein phosphorylation [GO:0006468]; pyramidal neuron development [GO:0021860]; receptor internalization involved in canonical Wnt signaling pathway [GO:2000286] GO:0002092; GO:0004672; GO:0005102; GO:0005524; GO:0005794; GO:0006468; GO:0007420; GO:0008333; GO:0010008; GO:0021860; GO:0030136; GO:0090090; GO:2000286; GO:2000370 9384 FUN_034158 1468 1050 907 836 1102 NA NA NA NA NA NA NA 9385 FUN_034155 27 0 35 198 14 NA NA NA NA NA NA NA 9386 FUN_034154 0 0 0 0 12 NA NA NA NA NA NA NA 9387 FUN_034157 0 16 11 47 4 NA NA NA NA NA NA NA 9388 FUN_034156 67 21 0 183 25 NA NA NA NA NA NA NA 9389 FUN_034151 2499 1989 1700 4815 3765 NA NA NA NA NA NA NA 9390 FUN_034150 97 93 29 130 228 NA NA NA NA NA NA NA 9391 FUN_034153 138 88 117 583 23 NA NA NA NA NA NA NA 9392 FUN_034152 0 0 9 0 14 NA NA NA NA NA NA NA 9393 FUN_009110 21 14 0 3 11 NA NA NA NA NA NA NA 9394 FUN_019161 59 0 1 106 0 NA NA NA NA NA NA NA 9395 FUN_043467 783 66 97 428 86 NA NA NA NA NA NA NA 9396 FUN_043466 484 99 59 266 8 NA NA NA NA NA NA NA 9397 FUN_043465 4575 13 9 1865 67 NA NA NA NA NA NA NA 9398 FUN_043464 444 0 5 111 0 NA NA NA NA NA NA NA 9399 FUN_043463 5826 368 303 4937 460 NA NA NA NA NA NA NA 9400 FUN_043462 121 2 0 110 0 NA NA NA NA NA NA NA 9401 FUN_043461 521 538 278 382 235 NA NA NA NA NA NA NA 9402 FUN_043460 2838 1736 1177 1710 1223 NA NA NA NA NA NA NA 9403 FUN_028673 15 0 0 0 15 NA NA NA NA NA NA NA 9404 FUN_043469 10 0 0 5 0 NA NA NA NA NA NA NA 9405 FUN_043468 482 379 117 93 257 NA NA NA NA NA NA NA 9406 FUN_030278 5 0 3 1 17 ptg000023l:10516655-10517418 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9407 FUN_030275 5 0 5 0 21 ptg000023l:10509876-10510639 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9408 FUN_030276 28 2 30 4 190 ptg000023l:10510903-10511890 Q6LAF1 6.31e-44 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9409 FUN_030271 2 0 4 0 18 ptg000023l:10501772-10502535 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9410 FUN_030273 3 0 6 0 19 ptg000023l:10505824-10506587 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9411 FUN_013099 976 812 280 2 578 ptg000008l:19569683-19571903 Q9Z2E3 1.57e-55 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 9412 FUN_041720 721 435 403 336 356 ptg000035l:6786981-6787997 Q568Q0 3.19e-31 8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18) Danio rerio (Zebrafish) (Brachydanio rerio) dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712] GO:0000287; GO:0044715; GO:0044716; GO:0044717; GO:0046057; GO:0046067; GO:0046712 9413 FUN_041720 721 435 403 336 356 ptg000035l:6786981-6787997 Q568Q0 3.19e-31 8-oxo-dGDP phosphatase NUDT18 (EC 3.6.1.58) (2-hydroxy-dADP phosphatase) (7,8-dihydro-8-oxoguanine phosphatase) (Nucleoside diphosphate-linked moiety X motif 18) (Nudix motif 18) Danio rerio (Zebrafish) (Brachydanio rerio) dADP catabolic process [GO:0046057]; dGDP catabolic process [GO:0046067]; GDP catabolic process [GO:0046712] GO:0000287; GO:0044715; GO:0044716; GO:0044717; GO:0046057; GO:0046067; GO:0046712 9414 FUN_002200 1047 1071 879 1511 1070 ntLink_6:22300812-22339007 P04323 1.48e-43 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 9415 FUN_002201 303 204 143 191 153 NA NA NA NA NA NA NA 9416 FUN_002202 403 722 278 365 221 NA NA NA NA NA NA NA 9417 FUN_002203 116 68 0 92 89 NA NA NA NA NA NA NA 9418 FUN_002206 21 327 64 0 182 NA NA NA NA NA NA NA 9419 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 4.18e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9420 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 1.55e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9421 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 1.25e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9422 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 1.98e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9423 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 1.81e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9424 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 9.6e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9425 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 2.13e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9426 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 1.85e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9427 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 3.95e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9428 FUN_043043 39 16 9 39 38 ptg000047l:3343034-3351385 Q96AY4 1.09e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9429 FUN_009116 275 253 148 96 48 ptg000004l:2876551-2885485 Q96AY4 2.21e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9430 FUN_009116 275 253 148 96 48 ptg000004l:2876551-2885485 Q96AY4 2.48e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9431 FUN_009116 275 253 148 96 48 ptg000004l:2876551-2885485 Q96AY4 9.53e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9432 FUN_031509 34 149 84 109 143 ptg000023l:22144905-22162998 A7SIM4 2.78e-22 Hapless 2 (Generative cell specific 1) Nematostella vectensis (Starlet sea anemone) single fertilization [GO:0007338] GO:0005886; GO:0007338; GO:0008289 9433 FUN_042279 0 23 86 35 335 NA NA NA NA NA NA NA 9434 FUN_042736 0 0 0 13 0 NA NA NA NA NA NA NA 9435 FUN_042737 4 0 5 0 11 ptg000040l:429061-430430 Q6LAF1 1.66e-46 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9436 FUN_004981 124 39 138 185 204 NA NA NA NA NA NA NA 9437 FUN_004980 59 12 44 64 96 NA NA NA NA NA NA NA 9438 FUN_004983 0 0 0 42 0 NA NA NA NA NA NA NA 9439 FUN_004982 528 293 244 315 393 NA NA NA NA NA NA NA 9440 FUN_004985 592 286 267 454 400 ntLink_8:29551049-29551955 Q6TGY8 4.77e-114 ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35) Danio rerio (Zebrafish) (Brachydanio rerio) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005737; GO:0005783; GO:0005789; GO:0042406; GO:0045050; GO:0071816; GO:0072546 9441 FUN_004987 0 27 17 2 0 NA NA NA NA NA NA NA 9442 FUN_004986 990 494 628 783 514 NA NA NA NA NA NA NA 9443 FUN_040468 2 137 0 0 153 NA NA NA NA NA NA NA 9444 FUN_040469 11 0 0 0 0 NA NA NA NA NA NA NA 9445 FUN_040466 0 65 0 25 11 NA NA NA NA NA NA NA 9446 FUN_040467 33 0 17 0 23 NA NA NA NA NA NA NA 9447 FUN_040464 4 0 0 0 128 NA NA NA NA NA NA NA 9448 FUN_040463 0 2 0 0 51 NA NA NA NA NA NA NA 9449 FUN_040461 3 14 2 4 8 NA NA NA NA NA NA NA 9450 FUN_013672 13 17 6 0 30 NA NA NA NA NA NA NA 9451 FUN_019413 6 250 189 131 158 NA NA NA NA NA NA NA 9452 FUN_002014 0 0 0 0 9 NA NA NA NA NA NA NA 9453 FUN_019412 10 239 195 101 189 NA NA NA NA NA NA NA 9454 FUN_032122 681 417 333 544 341 ptg000023l:29017088-29021517 Q66KE9 9.24e-36 Protein FAM161A Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0005737; GO:0005856; GO:0005929; GO:0030030 9455 FUN_032123 2003 1343 831 1808 1700 NA NA NA NA NA NA NA 9456 FUN_032120 17837 15830 13620 14808 10020 NA NA NA NA NA NA NA 9457 FUN_032121 279 237 182 235 197 NA NA NA NA NA NA NA 9458 FUN_032126 70 80 68 113 89 NA NA NA NA NA NA NA 9459 FUN_032127 2567 874 1424 2645 2039 NA NA NA NA NA NA NA 9460 FUN_032124 5427 3530 3393 8347 5705 NA NA NA NA NA NA NA 9461 FUN_032125 143 107 52 101 150 NA NA NA NA NA NA NA 9462 FUN_032128 452 362 306 258 579 NA NA NA NA NA NA NA 9463 FUN_032129 557 284 292 386 755 NA NA NA NA NA NA NA 9464 FUN_019415 2 2 3 2 27 NA NA NA NA NA NA NA 9465 FUN_019414 4 59 88 69 125 NA NA NA NA NA NA NA 9466 FUN_000196 350 271 150 432 799 NA NA NA NA NA NA NA 9467 FUN_000197 3031 1278 1458 2541 1699 NA NA NA NA NA NA NA 9468 FUN_000194 3290 2212 2263 3415 2141 NA NA NA NA NA NA NA 9469 FUN_000195 414 203 212 430 264 NA NA NA NA NA NA NA 9470 FUN_000192 1973 1489 730 1031 699 NA NA NA NA NA NA NA 9471 FUN_000193 656 599 429 718 477 NA NA NA NA NA NA NA 9472 FUN_000190 1849 1397 490 1297 1035 NA NA NA NA NA NA NA 9473 FUN_000191 8070 9711 4128 4633 5477 NA NA NA NA NA NA NA 9474 FUN_000198 3053 4687 3107 2653 1113 NA NA NA NA NA NA NA 9475 FUN_000199 0 0 0 91 36 NA NA NA NA NA NA NA 9476 FUN_006489 583 392 448 649 703 NA NA NA NA NA NA NA 9477 FUN_000228 699 726 387 496 531 ntLink_6:530517-538556 P51159 8.7e-22 Ras-related protein Rab-27A (Rab-27) (EC 3.6.5.2) (GTP-binding protein Ram) Homo sapiens (Human) antigen processing and presentation [GO:0019882]; blood coagulation [GO:0007596]; complement-dependent cytotoxicity [GO:0097278]; cytotoxic T cell degranulation [GO:0043316]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; melanocyte differentiation [GO:0030318]; melanosome localization [GO:0032400]; melanosome transport [GO:0032402]; multivesicular body organization [GO:0036257]; multivesicular body sorting pathway [GO:0071985]; natural killer cell degranulation [GO:0043320]; positive regulation of constitutive secretory pathway [GO:1903435]; positive regulation of exocytosis [GO:0045921]; positive regulation of gene expression [GO:0010628]; positive regulation of phagocytosis [GO:0050766]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of regulated secretory pathway [GO:1903307]; synaptic vesicle transport [GO:0048489]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0003924; GO:0003925; GO:0005525; GO:0005576; GO:0005764; GO:0005770; GO:0005794; GO:0005829; GO:0006887; GO:0007596; GO:0010628; GO:0016192; GO:0016324; GO:0019003; GO:0019882; GO:0019904; GO:0030141; GO:0030318; GO:0030425; GO:0030667; GO:0031489; GO:0032400; GO:0032402; GO:0032585; GO:0033093; GO:0033162; GO:0035580; GO:0036257; GO:0042470; GO:0043316; GO:0043320; GO:0045921; GO:0048489; GO:0050766; GO:0070062; GO:0070382; GO:0071985; GO:0097278; GO:1903307; GO:1903428; GO:1903435; GO:1990182 9478 FUN_008434 72 254 64 579 581 NA NA NA NA NA NA NA 9479 FUN_008437 4004 2234 1957 3596 3283 ptg000002l:11537411-11546910 Q62245 4.99e-32 Son of sevenless homolog 1 (SOS-1) (mSOS-1) Mus musculus (Mouse) B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; lymphocyte homeostasis [GO:0002260]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of biological quality [GO:0065008]; regulation of cell population proliferation [GO:0042127]; regulation of MAP kinase activity [GO:0043405]; regulation of pro-B cell differentiation [GO:2000973]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; small GTPase mediated signal transduction [GO:0007264]; vitellogenesis [GO:0007296] GO:0001782; GO:0001942; GO:0002260; GO:0003007; GO:0003209; GO:0003344; GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0007173; GO:0007264; GO:0007265; GO:0007296; GO:0008286; GO:0008543; GO:0014069; GO:0017124; GO:0033081; GO:0035264; GO:0042127; GO:0042129; GO:0043025; GO:0043405; GO:0043539; GO:0043547; GO:0045742; GO:0046579; GO:0046982; GO:0048009; GO:0048011; GO:0048514; GO:0050853; GO:0051057; GO:0060021; GO:0061029; GO:0061384; GO:0065008; GO:1904693; GO:1905360; GO:2000973 9480 FUN_008437 4004 2234 1957 3596 3283 ptg000002l:11537411-11546910 Q62245 4.99e-32 Son of sevenless homolog 1 (SOS-1) (mSOS-1) Mus musculus (Mouse) B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; lymphocyte homeostasis [GO:0002260]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of biological quality [GO:0065008]; regulation of cell population proliferation [GO:0042127]; regulation of MAP kinase activity [GO:0043405]; regulation of pro-B cell differentiation [GO:2000973]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; small GTPase mediated signal transduction [GO:0007264]; vitellogenesis [GO:0007296] GO:0001782; GO:0001942; GO:0002260; GO:0003007; GO:0003209; GO:0003344; GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0007173; GO:0007264; GO:0007265; GO:0007296; GO:0008286; GO:0008543; GO:0014069; GO:0017124; GO:0033081; GO:0035264; GO:0042127; GO:0042129; GO:0043025; GO:0043405; GO:0043539; GO:0043547; GO:0045742; GO:0046579; GO:0046982; GO:0048009; GO:0048011; GO:0048514; GO:0050853; GO:0051057; GO:0060021; GO:0061029; GO:0061384; GO:0065008; GO:1904693; GO:1905360; GO:2000973 9481 FUN_008436 2954 1709 1422 2212 1769 ptg000002l:11523001-11536864 Q07889 6.21e-27 Son of sevenless homolog 1 (SOS-1) Homo sapiens (Human) axon guidance [GO:0007411]; B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; blood vessel morphogenesis [GO:0048514]; cardiac atrium morphogenesis [GO:0003209]; cytokine-mediated signaling pathway [GO:0019221]; epidermal growth factor receptor signaling pathway [GO:0007173]; eyelid development in camera-type eye [GO:0061029]; Fc-epsilon receptor signaling pathway [GO:0038095]; fibroblast growth factor receptor signaling pathway [GO:0008543]; hair follicle development [GO:0001942]; heart trabecula morphogenesis [GO:0061384]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; leukocyte migration [GO:0050900]; midbrain morphogenesis [GO:1904693]; multicellular organism growth [GO:0035264]; neurotrophin TRK receptor signaling pathway [GO:0048011]; pericardium morphogenesis [GO:0003344]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of GTPase activity [GO:0043547]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; Ras protein signal transduction [GO:0007265]; regulation of cell population proliferation [GO:0042127]; regulation of MAP kinase activity [GO:0043405]; regulation of pro-B cell differentiation [GO:2000973]; regulation of T cell differentiation in thymus [GO:0033081]; regulation of T cell proliferation [GO:0042129]; regulation of transcription by RNA polymerase II [GO:0006357]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; vitellogenesis [GO:0007296] GO:0001782; GO:0001942; GO:0003209; GO:0003344; GO:0005085; GO:0005096; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0007165; GO:0007173; GO:0007265; GO:0007296; GO:0007411; GO:0008286; GO:0008543; GO:0014069; GO:0017124; GO:0019221; GO:0033081; GO:0035264; GO:0038095; GO:0042127; GO:0042129; GO:0043025; GO:0043405; GO:0043539; GO:0043547; GO:0045742; GO:0046982; GO:0048009; GO:0048011; GO:0048514; GO:0050853; GO:0050900; GO:0051057; GO:0060021; GO:0061029; GO:0061384; GO:1904693; GO:1905360; GO:2000973 9482 FUN_008431 143 99 73 118 142 NA NA NA NA NA NA NA 9483 FUN_008433 31 290 30 598 636 NA NA NA NA NA NA NA 9484 FUN_008432 6 0 0 0 0 NA NA NA NA NA NA NA 9485 FUN_008439 78 0 39 0 266 ptg000002l:11570381-11571632 P12804 2e-29 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 9486 FUN_013934 0 6 0 0 0 NA NA NA NA NA NA NA 9487 FUN_013935 71 14 0 0 0 NA NA NA NA NA NA NA 9488 FUN_041416 0 3 9 0 29 NA NA NA NA NA NA NA 9489 FUN_041417 962 2648 487 900 3636 ptg000035l:3477937-3480623 R1G6M4 8.56e-97 Dimethylsulfonioproprionate lyase 3 (DMSP lyase 3) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 3) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 9490 FUN_041410 17930 11713 6825 12292 9132 NA NA NA NA NA NA NA 9491 FUN_013931 0 10 8 0 0 NA NA NA NA NA NA NA 9492 FUN_013932 0 0 22 0 28 NA NA NA NA NA NA NA 9493 FUN_013933 7 2 0 11 1 NA NA NA NA NA NA NA 9494 FUN_041419 10 0 0 18 12 NA NA NA NA NA NA NA 9495 FUN_033292 5 370 47 839 8 NA NA NA NA NA NA NA 9496 FUN_033291 1 212 2 616 6 NA NA NA NA NA NA NA 9497 FUN_033290 0 290 274 422 0 NA NA NA NA NA NA NA 9498 FUN_033297 218 104 151 213 172 NA NA NA NA NA NA NA 9499 FUN_033296 33 14 11 41 50 NA NA NA NA NA NA NA 9500 FUN_033295 24 0 6 0 26 NA NA NA NA NA NA NA 9501 FUN_033294 23 0 21 0 19 NA NA NA NA NA NA NA 9502 FUN_033299 56 0 44 0 46 NA NA NA NA NA NA NA 9503 FUN_033298 729 370 522 868 587 NA NA NA NA NA NA NA 9504 FUN_043206 75 36 46 171 28 NA NA NA NA NA NA NA 9505 FUN_037805 695 559 420 611 330 NA NA NA NA NA NA NA 9506 FUN_029157 5 0 4 0 13 NA NA NA NA NA NA NA 9507 FUN_029156 1019 968 881 1166 956 ptg000022l:8778506-8796190 Q6DEZ2 3.48e-53 Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0005737; GO:0005886 9508 FUN_029156 1019 968 881 1166 956 ptg000022l:8778506-8796190 Q6DEZ2 2.06e-24 Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0005737; GO:0005886 9509 FUN_029156 1019 968 881 1166 956 ptg000022l:8778506-8796190 Q6DEZ2 3.91e-24 Constitutive coactivator of PPAR-gamma-like protein 1 homolog (Protein FAM120A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003723; GO:0005737; GO:0005886 9510 FUN_029155 4953 4261 1744 3036 2477 NA NA NA NA NA NA NA 9511 FUN_029153 187 47 88 389 71 NA NA NA NA NA NA NA 9512 FUN_029152 16 0 0 0 7 NA NA NA NA NA NA NA 9513 FUN_029151 18912 17245 9892 16625 8946 ptg000022l:8725670-8735964 P29401 1.91e-26 Transketolase (TK) (EC 2.2.1.1) Homo sapiens (Human) glyceraldehyde-3-phosphate biosynthetic process [GO:0046166]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; regulation of growth [GO:0040008]; ribose phosphate biosynthetic process [GO:0046390] GO:0000287; GO:0004802; GO:0005509; GO:0005654; GO:0005777; GO:0005789; GO:0005829; GO:0006098; GO:0009052; GO:0016604; GO:0030976; GO:0031982; GO:0040008; GO:0042803; GO:0046166; GO:0046390; GO:0070062 9514 FUN_029150 6620 6259 3808 6373 3712 ptg000022l:8712454-8722929 Q60HC7 5.56e-37 Transketolase (TK) (EC 2.2.1.1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0004802; GO:0046872 9515 FUN_024497 0 0 0 12 0 NA NA NA NA NA NA NA 9516 FUN_014315 116 13 0 17 0 NA NA NA NA NA NA NA 9517 FUN_033745 2156 2263 1542 1772 974 ptg000024l:915083-918049 Q6YGZ4 4.08e-62 Circadian locomoter output cycles protein kaput Tyto alba (Barn owl) cellular response to DNA damage stimulus [GO:0006974]; protein acetylation [GO:0006473]; response to redox state [GO:0051775]; rhythmic process [GO:0048511] GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0005829; GO:0006473; GO:0006974; GO:0046983; GO:0048511; GO:0051775 9518 FUN_033744 2561 3595 1961 3817 2381 ptg000024l:910116-911901 Q99743 5.56e-54 Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Basic-helix-loop-helix-PAS protein MOP4) (Class E basic helix-loop-helix protein 9) (bHLHe9) (Member of PAS protein 4) (PAS domain-containing protein 4) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; central nervous system development [GO:0007417]; circadian regulation of gene expression [GO:0032922]; negative regulation of cell death [GO:0060548]; positive regulation of behavioral fear response [GO:2000987]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of transcription by RNA polymerase II [GO:0006357]; response to redox state [GO:0051775]; response to xenobiotic stimulus [GO:0009410] GO:0000785; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0006974; GO:0007417; GO:0009410; GO:0032922; GO:0045739; GO:0045893; GO:0045944; GO:0046872; GO:0046983; GO:0051775; GO:0051879; GO:0060548; GO:1990513; GO:1990837; GO:2000987; GO:2001020 9519 FUN_033747 2623 2185 1312 1763 1455 NA NA NA NA NA NA NA 9520 FUN_033746 2568 3111 1592 1812 1229 NA NA NA NA NA NA NA 9521 FUN_033741 89 23 40 51 77 NA NA NA NA NA NA NA 9522 FUN_033740 248 355 229 211 349 NA NA NA NA NA NA NA 9523 FUN_033743 47 60 123 74 88 NA NA NA NA NA NA NA 9524 FUN_033742 59 24 23 24 11 NA NA NA NA NA NA NA 9525 FUN_022455 56 108 109 497 257 NA NA NA NA NA NA NA 9526 FUN_033748 11434 21844 10630 18806 15050 NA NA NA NA NA NA NA 9527 FUN_005323 14 0 36 34 0 ntLink_8:34033118-34036102 Q3UZD5 2.96e-39 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 9528 FUN_005323 14 0 36 34 0 ntLink_8:34033118-34036102 Q3UZD5 4.93e-22 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 9529 FUN_005320 1104 202 577 662 878 ntLink_8:33993755-34001214 Q3UZD5 3.91e-45 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 9530 FUN_005321 3947 4900 2062 3870 2763 NA NA NA NA NA NA NA 9531 FUN_000134 4 0 8 0 13 ntLink_4:198471-199234 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9532 FUN_000135 11 4 10 0 184 ntLink_4:199956-202267 P35061 6.42e-78 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9533 FUN_003759 0 0 0 0 13 NA NA NA NA NA NA NA 9534 FUN_044010 210 149 7 230 26 ptg000070l:16199-20617 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9535 FUN_044010 210 149 7 230 26 ptg000070l:16199-20617 Q96AY4 2.4e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9536 FUN_044010 210 149 7 230 26 ptg000070l:16199-20617 Q96AY4 4e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9537 FUN_044010 210 149 7 230 26 ptg000070l:16199-20617 Q96AY4 5.59e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9538 FUN_000136 2 0 9 0 14 ntLink_4:202531-203294 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9539 FUN_003750 0 31 0 0 0 NA NA NA NA NA NA NA 9540 FUN_003757 0 0 6 0 38 NA NA NA NA NA NA NA 9541 FUN_003756 0 0 7 0 48 NA NA NA NA NA NA NA 9542 FUN_044015 256 63 130 334 155 NA NA NA NA NA NA NA 9543 FUN_044014 20 0 24 0 11 NA NA NA NA NA NA NA 9544 FUN_022452 25 0 0 18 43 NA NA NA NA NA NA NA 9545 FUN_028208 0 13 0 0 0 NA NA NA NA NA NA NA 9546 FUN_028209 43 45 58 95 55 NA NA NA NA NA NA NA 9547 FUN_010779 1036 664 440 737 614 ptg000007l:2703000-2710932 Q9D1P2 2.71e-24 Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone H4-K16 acetylation [GO:0043984]; histone H4-K5 acetylation [GO:0043981]; histone H4-K8 acetylation [GO:0043982]; myeloid cell differentiation [GO:0030099]; negative regulation of DNA-templated transcription [GO:0045892]; neurogenesis [GO:0022008]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of autophagy [GO:0010506]; regulation of dosage compensation by inactivation of X chromosome [GO:1900095] GO:0000123; GO:0000776; GO:0003712; GO:0003713; GO:0005634; GO:0005654; GO:0006325; GO:0010506; GO:0016363; GO:0016407; GO:0019899; GO:0022008; GO:0030099; GO:0042393; GO:0043981; GO:0043982; GO:0043984; GO:0043995; GO:0043996; GO:0044545; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0046972; GO:0051571; GO:0061629; GO:0071339; GO:0072487; GO:1900095 9548 FUN_010778 52 24 12 40 156 NA NA NA NA NA NA NA 9549 FUN_010777 0 10 0 13 0 ptg000007l:2692262-2696932 A1L1W9 7.8e-21 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 9550 FUN_010776 556 101 162 181 185 NA NA NA NA NA NA NA 9551 FUN_010775 11542 6933 5234 7875 4612 ptg000007l:2677428-2685483 P20232 3.9e-25 Transcription elongation factor S-II (RNA polymerase II elongation factor DMS-II) (TFIIS) Drosophila melanogaster (Fruit fly) DNA-templated transcription [GO:0006351]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0003677; GO:0005634; GO:0006351; GO:0006368; GO:0008270 9552 FUN_028207 30 198 163 14 0 NA NA NA NA NA NA NA 9553 FUN_010773 572 839 593 676 337 NA NA NA NA NA NA NA 9554 FUN_010772 586 281 231 552 228 ptg000007l:2634498-2635542 A5A4K9 8.4e-21 Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasing peptide receptor) (GHRP) (Ghrelin receptor) Oryctolagus cuniculus (Rabbit) actin polymerization or depolymerization [GO:0008154]; adult feeding behavior [GO:0008343]; cellular response to insulin stimulus [GO:0032869]; decidualization [GO:0046697]; growth hormone secretion [GO:0030252]; hormone-mediated signaling pathway [GO:0009755]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of appetite [GO:0032100]; positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568]; positive regulation of multicellular organism growth [GO:0040018]; regulation of synapse assembly [GO:0051963]; response to food [GO:0032094] GO:0001616; GO:0005886; GO:0008154; GO:0008343; GO:0009755; GO:0009986; GO:0016520; GO:0030252; GO:0032094; GO:0032100; GO:0032691; GO:0032715; GO:0032720; GO:0032869; GO:0040018; GO:0043005; GO:0043568; GO:0045121; GO:0046697; GO:0048009; GO:0050728; GO:0051963 9555 FUN_010771 63 225 155 151 226 NA NA NA NA NA NA NA 9556 FUN_010770 183 505 440 373 197 NA NA NA NA NA NA NA 9557 FUN_034218 0 0 26 0 10 NA NA NA NA NA NA NA 9558 FUN_022451 801 1342 611 1048 1035 NA NA NA NA NA NA NA 9559 FUN_034212 0 49 34 85 76 NA NA NA NA NA NA NA 9560 FUN_034211 1741 927 846 1897 1444 NA NA NA NA NA NA NA 9561 FUN_034216 276 258 346 514 407 NA NA NA NA NA NA NA 9562 FUN_034217 951 697 405 671 439 NA NA NA NA NA NA NA 9563 FUN_034214 286 294 178 347 304 NA NA NA NA NA NA NA 9564 FUN_034215 0 6 0 0 0 NA NA NA NA NA NA NA 9565 FUN_012683 6 4 0 7 7 NA NA NA NA NA NA NA 9566 FUN_012682 5207 3199 3042 4180 2773 ptg000008l:11317044-11319055 O22943 1.38e-72 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 9567 FUN_012685 4991 6310 2470 4567 2310 NA NA NA NA NA NA NA 9568 FUN_012684 41053 33005 18082 15230 16367 NA NA NA NA NA NA NA 9569 FUN_012687 678 1277 655 1049 424 NA NA NA NA NA NA NA 9570 FUN_012686 5492 3880 2366 4647 3520 ptg000008l:11355613-11368213 Q06124 4.67e-25 Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3) Homo sapiens (Human) abortive mitotic cell cycle [GO:0033277]; atrioventricular canal development [GO:0036302]; axonogenesis [GO:0007409]; Bergmann glial cell differentiation [GO:0060020]; brain development [GO:0007420]; cellular response to epidermal growth factor stimulus [GO:0071364]; cerebellar cortex formation [GO:0021697]; cytokine-mediated signaling pathway [GO:0019221]; DNA damage checkpoint signaling [GO:0000077]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB signaling pathway [GO:0038127]; face morphogenesis [GO:0060325]; fibroblast growth factor receptor signaling pathway [GO:0008543]; genitalia development [GO:0048806]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; homeostasis of number of cells within a tissue [GO:0048873]; hormone metabolic process [GO:0042445]; hormone-mediated signaling pathway [GO:0009755]; inner ear development [GO:0048839]; integrin-mediated signaling pathway [GO:0007229]; intestinal epithelial cell migration [GO:0061582]; megakaryocyte development [GO:0035855]; microvillus organization [GO:0032528]; multicellular organism growth [GO:0035264]; multicellular organismal reproductive process [GO:0048609]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of cortisol secretion [GO:0051463]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of insulin secretion [GO:0046676]; neurotrophin TRK receptor signaling pathway [GO:0048011]; organ growth [GO:0035265]; peptidyl-tyrosine dephosphorylation [GO:0035335]; platelet formation [GO:0030220]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose import [GO:0046326]; positive regulation of hormone secretion [GO:0046887]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of ossification [GO:0045778]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of tumor necrosis factor production [GO:0032760]; protein dephosphorylation [GO:0006470]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of protein export from nucleus [GO:0046825]; regulation of protein-containing complex assembly [GO:0043254]; regulation of type I interferon-mediated signaling pathway [GO:0060338]; T cell costimulation [GO:0031295]; triglyceride metabolic process [GO:0006641] GO:0000077; GO:0001784; GO:0004721; GO:0004725; GO:0004726; GO:0005158; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006470; GO:0006641; GO:0007173; GO:0007229; GO:0007409; GO:0007420; GO:0007507; GO:0008543; GO:0009755; GO:0019221; GO:0019901; GO:0021697; GO:0030159; GO:0030220; GO:0030971; GO:0031295; GO:0032331; GO:0032528; GO:0032728; GO:0032755; GO:0032760; GO:0032991; GO:0033277; GO:0033628; GO:0033629; GO:0035264; GO:0035265; GO:0035335; GO:0035855; GO:0036302; GO:0038127; GO:0042445; GO:0042593; GO:0043254; GO:0045296; GO:0045778; GO:0045931; GO:0046326; GO:0046628; GO:0046676; GO:0046825; GO:0046887; GO:0048008; GO:0048011; GO:0048013; GO:0048609; GO:0048806; GO:0048839; GO:0048873; GO:0050731; GO:0050839; GO:0051428; GO:0051463; GO:0060020; GO:0060125; GO:0060325; GO:0060338; GO:0061582; GO:0070374; GO:0071364; GO:1990782 9571 FUN_012689 1371 859 620 1331 1855 NA NA NA NA NA NA NA 9572 FUN_025819 3305 1478 1530 2874 1927 ptg000020l:893250-899168 Q60HE9 5.72e-124 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 9573 FUN_025819 3305 1478 1530 2874 1927 ptg000020l:893250-899168 Q60HE9 1.98e-117 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 9574 FUN_011792 21 6 29 2 156 NA NA NA NA NA NA NA 9575 FUN_011793 90 70 178 145 492 NA NA NA NA NA NA NA 9576 FUN_011790 51 12 0 24 68 NA NA NA NA NA NA NA 9577 FUN_011796 20 82 79 126 0 NA NA NA NA NA NA NA 9578 FUN_011794 945 445 500 714 881 NA NA NA NA NA NA NA 9579 FUN_011795 44 58 15 175 49 ptg000008l:1569252-1571542 P48442 1.1e-33 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 9580 FUN_030357 7 0 9 0 23 ptg000023l:10689562-10690325 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9581 FUN_014452 1345 1082 1037 1481 1347 NA NA NA NA NA NA NA 9582 FUN_014453 28 27 106 234 409 NA NA NA NA NA NA NA 9583 FUN_014450 6320 6282 3778 5908 4289 ptg000009l:308923-313950 Q9QXN5 5.85e-40 Inositol oxygenase (EC 1.13.99.1) (Aldehyde reductase-like 6) (Myo-inositol oxygenase) (MI oxygenase) (Renal-specific oxidoreductase) Mus musculus (Mouse) inositol catabolic process [GO:0019310] GO:0004033; GO:0005737; GO:0008199; GO:0016234; GO:0016491; GO:0016651; GO:0016701; GO:0019310; GO:0050113; GO:0050661 9584 FUN_007781 1352 1347 554 1093 26 NA NA NA NA NA NA NA 9585 FUN_013488 108 0 35 22 444 NA NA NA NA NA NA NA 9586 FUN_013489 0 0 0 0 42 NA NA NA NA NA NA NA 9587 FUN_014454 341 431 984 1538 3506 ptg000009l:332491-334622 Q29RZ5 1.45e-26 Transport and Golgi organization protein 2 homolog Bos taurus (Bovine) Golgi organization [GO:0007030]; protein secretion [GO:0009306] GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0007030; GO:0009306 9588 FUN_025813 480 221 223 345 181 NA NA NA NA NA NA NA 9589 FUN_013484 1392 1289 923 2788 300 ptg000008l:23204136-23216276 Q7RTR2 1.45e-77 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9590 FUN_013484 1392 1289 923 2788 300 ptg000008l:23204136-23216276 Q7RTR2 2.53e-77 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9591 FUN_013484 1392 1289 923 2788 300 ptg000008l:23204136-23216276 Q7RTR2 3.36e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9592 FUN_013484 1392 1289 923 2788 300 ptg000008l:23204136-23216276 Q7RTR2 1.06e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9593 FUN_013484 1392 1289 923 2788 300 ptg000008l:23204136-23216276 Q7RTR2 5.63e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9594 FUN_013486 239 28 82 154 781 NA NA NA NA NA NA NA 9595 FUN_014459 540 662 611 655 694 ptg000009l:383312-384913 Q7YRC1 1.82e-51 AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) Bos taurus (Bovine) xenobiotic metabolic process [GO:0006805] GO:0003712; GO:0003755; GO:0005737; GO:0006805 9596 FUN_013480 1251 1062 725 1860 340 ptg000008l:23154675-23160252 Q7RTR2 3.58e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9597 FUN_013480 1251 1062 725 1860 340 ptg000008l:23154675-23160252 Q7RTR2 6.19e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 9598 FUN_013481 3 18 12 0 6 NA NA NA NA NA NA NA 9599 FUN_013482 17 117 34 3 0 NA NA NA NA NA NA NA 9600 FUN_013483 39 66 27 0 7 ptg000008l:23187640-23194146 Q8VD65 8.22e-23 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 9601 FUN_025816 5899 2497 1913 3909 3639 ptg000020l:882889-888478 Q60HE9 7.45e-122 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 9602 FUN_025816 5899 2497 1913 3909 3639 ptg000020l:882889-888478 Q60HE9 8.23e-120 Lysosomal alpha-mannosidase (Laman) (EC 3.2.1.24) (Lysosomal acid alpha-mannosidase) (Mannosidase alpha class 2B member 1) (Mannosidase alpha-B) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) mannose metabolic process [GO:0006013] GO:0004559; GO:0005764; GO:0006013; GO:0030246; GO:0046872 9603 FUN_043108 202 187 198 224 171 ptg000047l:4231803-4233717 O73853 7.86e-96 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 9604 FUN_011429 27 23 27 21 59 NA NA NA NA NA NA NA 9605 FUN_043104 1891 1613 773 1411 1146 NA NA NA NA NA NA NA 9606 FUN_043105 2794 4896 2748 3491 2185 NA NA NA NA NA NA NA 9607 FUN_011426 27 0 85 21 124 NA NA NA NA NA NA NA 9608 FUN_011427 54 14 39 5 118 NA NA NA NA NA NA NA 9609 FUN_043100 0 0 1 0 6 NA NA NA NA NA NA NA 9610 FUN_043102 47 94 59 12 58 NA NA NA NA NA NA NA 9611 FUN_013156 320 411 206 136 303 ptg000008l:20206557-20211231 Q6P3S6 5.54e-39 F-box only protein 42 (Just one F-box and Kelch domain-containing protein) Homo sapiens (Human) NA GO:0019005; GO:1990756 9612 FUN_013154 101 424 117 211 604 NA NA NA NA NA NA NA 9613 FUN_013155 1634 1833 1008 1967 1468 NA NA NA NA NA NA NA 9614 FUN_013153 4327 2229 2874 3865 3626 NA NA NA NA NA NA NA 9615 FUN_013151 57 183 12 49 0 NA NA NA NA NA NA NA 9616 FUN_013159 3524 3754 2090 2776 2510 ptg000008l:20216186-20217986 Q3SYV5 7.58e-56 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 9617 FUN_029638 342 161 12 432 108 NA NA NA NA NA NA NA 9618 FUN_029639 1733 1285 1005 1171 857 NA NA NA NA NA NA NA 9619 FUN_029632 20 9 14 6 11 ptg000023l:3944439-3947647 P79729 2.29e-26 Desert hedgehog protein (DHH) Danio rerio (Zebrafish) (Brachydanio rerio) cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; proteolysis [GO:0006508]; regulation of gene expression [GO:0010468]; smoothened signaling pathway [GO:0007224] GO:0001708; GO:0005113; GO:0005509; GO:0005615; GO:0005886; GO:0006508; GO:0007224; GO:0007267; GO:0008233; GO:0010468 9620 FUN_029633 12 29 29 0 10 NA NA NA NA NA NA NA 9621 FUN_029630 9 11 25 31 26 NA NA NA NA NA NA NA 9622 FUN_029631 6 1 2 2 1 NA NA NA NA NA NA NA 9623 FUN_029637 567 159 140 78 139 NA NA NA NA NA NA NA 9624 FUN_023779 0 9 42 0 0 NA NA NA NA NA NA NA 9625 FUN_023778 0 16 15 0 3 NA NA NA NA NA NA NA 9626 FUN_023771 8 0 2 2 0 NA NA NA NA NA NA NA 9627 FUN_023770 0 0 0 0 8 NA NA NA NA NA NA NA 9628 FUN_023772 935 779 586 984 812 NA NA NA NA NA NA NA 9629 FUN_023775 286 19 122 111 316 NA NA NA NA NA NA NA 9630 FUN_023774 1829 1927 1419 2961 1391 ptg000017l:11009702-11012011 Q8BXN7 1.06e-55 Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (Protein phosphatase 2C isoform kappa) (PP2C-kappa) Mus musculus (Mouse) peptidyl-threonine dephosphorylation [GO:0035970] GO:0004722; GO:0005739; GO:0005759; GO:0017018; GO:0035970; GO:0046872 9631 FUN_023777 9 0 0 0 44 NA NA NA NA NA NA NA 9632 FUN_009280 620 169 193 67 471 NA NA NA NA NA NA NA 9633 FUN_009283 0 4 0 34 8 NA NA NA NA NA NA NA 9634 FUN_009285 2845 2706 2085 626 1183 NA NA NA NA NA NA NA 9635 FUN_009284 9 0 0 16 27 NA NA NA NA NA NA NA 9636 FUN_009287 19 49 4 536 135 NA NA NA NA NA NA NA 9637 FUN_009286 0 6 0 0 0 NA NA NA NA NA NA NA 9638 FUN_009289 1192 2001 1541 411 398 NA NA NA NA NA NA NA 9639 FUN_009288 753 464 452 816 425 NA NA NA NA NA NA NA 9640 FUN_030351 7 0 8 0 24 ptg000023l:10677408-10678169 P84239 3.88e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9641 FUN_026690 0 7 0 0 0 NA NA NA NA NA NA NA 9642 FUN_026693 4 181 6 2 0 NA NA NA NA NA NA NA 9643 FUN_026692 0 7 15 0 32 NA NA NA NA NA NA NA 9644 FUN_026699 128 723 150 210 12 ptg000020l:12606837-12610863 Q96AY4 4.46e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9645 FUN_026699 128 723 150 210 12 ptg000020l:12606837-12610863 Q96AY4 6.81e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9646 FUN_026699 128 723 150 210 12 ptg000020l:12606837-12610863 Q96AY4 1.72e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9647 FUN_026699 128 723 150 210 12 ptg000020l:12606837-12610863 Q96AY4 7.37e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9648 FUN_015414 153 36 109 101 257 NA NA NA NA NA NA NA 9649 FUN_015417 0 30 12 0 34 NA NA NA NA NA NA NA 9650 FUN_015416 13 0 10 18 59 NA NA NA NA NA NA NA 9651 FUN_015411 4732 4250 2444 4457 3809 ptg000009l:9852835-9881318 Q7ZVM1 9.6e-26 WASH complex subunit 5 (WASH complex subunit strumpellin) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; axonogenesis [GO:0007409]; endosome fission [GO:0140285]; endosome organization [GO:0007032]; heart contraction [GO:0060047]; neuron development [GO:0048666]; protein transport [GO:0015031]; regulation of actin nucleation [GO:0051125] GO:0005768; GO:0005769; GO:0007032; GO:0007409; GO:0015031; GO:0030041; GO:0048666; GO:0051125; GO:0060047; GO:0071203; GO:0140285 9652 FUN_015411 4732 4250 2444 4457 3809 ptg000009l:9852835-9881318 Q7ZVM1 5.7e-22 WASH complex subunit 5 (WASH complex subunit strumpellin) Danio rerio (Zebrafish) (Brachydanio rerio) actin filament polymerization [GO:0030041]; axonogenesis [GO:0007409]; endosome fission [GO:0140285]; endosome organization [GO:0007032]; heart contraction [GO:0060047]; neuron development [GO:0048666]; protein transport [GO:0015031]; regulation of actin nucleation [GO:0051125] GO:0005768; GO:0005769; GO:0007032; GO:0007409; GO:0015031; GO:0030041; GO:0048666; GO:0051125; GO:0060047; GO:0071203; GO:0140285 9653 FUN_015410 529 338 287 523 724 NA NA NA NA NA NA NA 9654 FUN_015413 0 0 56 6 46 NA NA NA NA NA NA NA 9655 FUN_015412 34 43 28 0 43 ptg000009l:9883133-9884183 O15973 4.44e-21 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 9656 FUN_008888 1365 600 626 964 686 NA NA NA NA NA NA NA 9657 FUN_008889 2929 2073 1984 4106 3430 NA NA NA NA NA NA NA 9658 FUN_008884 2854 2092 1978 2881 2765 NA NA NA NA NA NA NA 9659 FUN_008885 1989 2859 1311 2192 1206 ptg000004l:277629-283152 Q8R4E0 1.1e-33 Interferon regulatory factor 2 (IRF-2) Sigmodon hispidus (Hispid cotton rat) NA GO:0000976; GO:0003700; GO:0005634 9660 FUN_008886 452 402 270 318 463 NA NA NA NA NA NA NA 9661 FUN_008887 29411 32939 15230 29375 10382 NA NA NA NA NA NA NA 9662 FUN_008880 993 1001 379 685 651 NA NA NA NA NA NA NA 9663 FUN_008881 1874 2472 1550 2396 1714 NA NA NA NA NA NA NA 9664 FUN_008882 3555 5168 3341 7758 5834 ptg000004l:249219-251903 Q96GY0 1.13e-21 Zinc finger C2HC domain-containing protein 1A Homo sapiens (Human) NA GO:0046872 9665 FUN_008883 22252 20759 12460 19765 12552 ptg000004l:252512-256398 Q15084 3.61e-92 Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) Homo sapiens (Human) protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0005615; GO:0005783; GO:0005788; GO:0005789; GO:0005793; GO:0005829; GO:0005886; GO:0006457; GO:0015035; GO:0034663; GO:0034976; GO:0042470; GO:0070062 9666 FUN_018762 15 5 3 36 1 NA NA NA NA NA NA NA 9667 FUN_018764 1839 1987 1041 0 2252 NA NA NA NA NA NA NA 9668 FUN_018765 11 32 5 12 33 NA NA NA NA NA NA NA 9669 FUN_018766 249 205 83 122 336 NA NA NA NA NA NA NA 9670 FUN_018767 0 0 0 18 21 NA NA NA NA NA NA NA 9671 FUN_018768 0 0 29 0 0 NA NA NA NA NA NA NA 9672 FUN_018769 0 6 36 17 3 NA NA NA NA NA NA NA 9673 FUN_024921 761 233 69 235 516 ptg000018l:12672360-12708080 P46023 4.14e-73 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 9674 FUN_024920 145 25 11 6 74 NA NA NA NA NA NA NA 9675 FUN_024923 573 928 117 247 717 ptg000018l:12772075-12794948 P46023 9.87e-70 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 9676 FUN_024922 390 77 0 0 121 ptg000018l:12712701-12759150 Q95SX7 1.62e-31 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 9677 FUN_024925 47 85 48 7 78 NA NA NA NA NA NA NA 9678 FUN_024924 0 60 0 0 78 NA NA NA NA NA NA NA 9679 FUN_024927 209 142 47 17 86 NA NA NA NA NA NA NA 9680 FUN_024929 2 11 2 0 17 NA NA NA NA NA NA NA 9681 FUN_038241 4111 1695 1895 4479 2529 NA NA NA NA NA NA NA 9682 FUN_038240 3116 1205 1288 1406 1354 NA NA NA NA NA NA NA 9683 FUN_038243 149 36 71 84 76 ptg000027l:4643905-4647884 P22770 6.21e-40 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 9684 FUN_038242 14 18 0 5 7 NA NA NA NA NA NA NA 9685 FUN_038245 28633 16124 14619 39315 34450 ptg000027l:4664402-4696130 Q91Z83 4.42e-27 Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta) Mus musculus (Mouse) adult heart development [GO:0007512]; ATP metabolic process [GO:0046034]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy in response to stress [GO:0014898]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; regulation of heart rate [GO:0002027]; regulation of slow-twitch skeletal muscle fiber contraction [GO:0031449]; regulation of the force of heart contraction [GO:0002026]; regulation of the force of skeletal muscle contraction [GO:0014728]; sarcomere organization [GO:0045214]; skeletal muscle contraction [GO:0003009]; striated muscle contraction [GO:0006941]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] GO:0000146; GO:0001725; GO:0002026; GO:0002027; GO:0003009; GO:0005516; GO:0005524; GO:0005737; GO:0005859; GO:0006936; GO:0006941; GO:0007512; GO:0014728; GO:0014883; GO:0014898; GO:0016459; GO:0016460; GO:0016887; GO:0030016; GO:0030017; GO:0030018; GO:0030049; GO:0031449; GO:0032982; GO:0042802; GO:0044877; GO:0045214; GO:0046034; GO:0051015; GO:0055010; GO:0060048 9686 FUN_038245 28633 16124 14619 39315 34450 ptg000027l:4664402-4696130 Q91Z83 1.37e-23 Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta) Mus musculus (Mouse) adult heart development [GO:0007512]; ATP metabolic process [GO:0046034]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy in response to stress [GO:0014898]; muscle contraction [GO:0006936]; muscle filament sliding [GO:0030049]; regulation of heart rate [GO:0002027]; regulation of slow-twitch skeletal muscle fiber contraction [GO:0031449]; regulation of the force of heart contraction [GO:0002026]; regulation of the force of skeletal muscle contraction [GO:0014728]; sarcomere organization [GO:0045214]; skeletal muscle contraction [GO:0003009]; striated muscle contraction [GO:0006941]; transition between fast and slow fiber [GO:0014883]; ventricular cardiac muscle tissue morphogenesis [GO:0055010] GO:0000146; GO:0001725; GO:0002026; GO:0002027; GO:0003009; GO:0005516; GO:0005524; GO:0005737; GO:0005859; GO:0006936; GO:0006941; GO:0007512; GO:0014728; GO:0014883; GO:0014898; GO:0016459; GO:0016460; GO:0016887; GO:0030016; GO:0030017; GO:0030018; GO:0030049; GO:0031449; GO:0032982; GO:0042802; GO:0044877; GO:0045214; GO:0046034; GO:0051015; GO:0055010; GO:0060048 9687 FUN_038244 285 212 126 453 99 ptg000027l:4652818-4658801 P18845 3.92e-56 Neuronal acetylcholine receptor subunit alpha-3 (GF-alpha-3) Carassius auratus (Goldfish) behavioral response to nicotine [GO:0035095]; nervous system development [GO:0007399]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084] GO:0005892; GO:0007165; GO:0007399; GO:0015464; GO:0022848; GO:0035095; GO:0045211; GO:0060084 9688 FUN_038247 1374 969 776 1770 2170 NA NA NA NA NA NA NA 9689 FUN_038246 1475 1006 1684 2243 2065 NA NA NA NA NA NA NA 9690 FUN_038249 27 59 41 390 198 NA NA NA NA NA NA NA 9691 FUN_038248 221 94 126 109 177 NA NA NA NA NA NA NA 9692 FUN_025346 325 78 342 605 2741 ptg000019l:1611115-1664316 Q9P2N4 1.04e-26 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 9693 FUN_025347 0 27 0 301 430 NA NA NA NA NA NA NA 9694 FUN_025344 5039 1913 2074 11926 11260 ptg000019l:1508351-1548391 Q9P2N4 8.28e-24 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 9695 FUN_025345 850 254 660 1771 4018 ptg000019l:1548774-1610344 B3EWZ3 2.47e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 9696 FUN_025345 850 254 660 1771 4018 ptg000019l:1548774-1610344 B3EWZ3 4.4e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 9697 FUN_025345 850 254 660 1771 4018 ptg000019l:1548774-1610344 B3EWZ3 4.89e-22 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 9698 FUN_025345 850 254 660 1771 4018 ptg000019l:1548774-1610344 B3EWZ3 4.03e-21 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 9699 FUN_025342 790 1890 2438 2218 1166 NA NA NA NA NA NA NA 9700 FUN_025343 21570 28280 13617 18095 15964 NA NA NA NA NA NA NA 9701 FUN_025340 0 259 274 738 487 NA NA NA NA NA NA NA 9702 FUN_025348 0 265 392 0 1114 NA NA NA NA NA NA NA 9703 FUN_025349 0 108 80 191 1057 ptg000019l:1687908-1705645 Q9P2N4 4.61e-27 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 9704 FUN_024699 11 0 5 12 20 NA NA NA NA NA NA NA 9705 FUN_024698 11 0 5 9 27 NA NA NA NA NA NA NA 9706 FUN_024692 302 243 255 69 171 NA NA NA NA NA NA NA 9707 FUN_024691 112 0 21 25 170 NA NA NA NA NA NA NA 9708 FUN_024690 0 0 32 0 22 NA NA NA NA NA NA NA 9709 FUN_024697 14 0 42 35 169 NA NA NA NA NA NA NA 9710 FUN_019410 0 0 13 0 84 NA NA NA NA NA NA NA 9711 FUN_030076 0 59 0 0 90 NA NA NA NA NA NA NA 9712 FUN_044346 7 0 8 5 21 NA NA NA NA NA NA NA 9713 FUN_030074 602 142 178 510 254 NA NA NA NA NA NA NA 9714 FUN_019419 4 64 122 69 116 NA NA NA NA NA NA NA 9715 FUN_019418 0 0 7 0 49 NA NA NA NA NA NA NA 9716 FUN_044348 7 0 6 11 21 NA NA NA NA NA NA NA 9717 FUN_001868 0 0 17 0 28 NA NA NA NA NA NA NA 9718 FUN_001865 1375 4785 2169 1667 2748 NA NA NA NA NA NA NA 9719 FUN_001867 1249 835 478 788 936 NA NA NA NA NA NA NA 9720 FUN_001866 13 0 13 0 1 NA NA NA NA NA NA NA 9721 FUN_001861 25 0 45 44 61 NA NA NA NA NA NA NA 9722 FUN_001860 444 239 219 398 328 ntLink_6:17128307-17128703 O14672 2.8e-28 Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) Homo sapiens (Human) adherens junction organization [GO:0034332]; amyloid precursor protein catabolic process [GO:0042987]; cell-cell signaling [GO:0007267]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; extracellular matrix disassembly [GO:0022617]; in utero embryonic development [GO:0001701]; integrin-mediated signaling pathway [GO:0007229]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; protein processing [GO:0016485]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] GO:0000139; GO:0001701; GO:0004175; GO:0004222; GO:0005102; GO:0005178; GO:0005634; GO:0005737; GO:0005788; GO:0005794; GO:0005798; GO:0005886; GO:0005912; GO:0005925; GO:0006468; GO:0006509; GO:0007162; GO:0007219; GO:0007229; GO:0007267; GO:0008237; GO:0008284; GO:0008593; GO:0009986; GO:0010629; GO:0010820; GO:0014069; GO:0016020; GO:0016485; GO:0017124; GO:0019901; GO:0022617; GO:0030136; GO:0030307; GO:0030335; GO:0030424; GO:0030425; GO:0034332; GO:0034612; GO:0035579; GO:0038004; GO:0042117; GO:0042803; GO:0042987; GO:0043231; GO:0046872; GO:0046930; GO:0046931; GO:0051089; GO:0060090; GO:0070062; GO:0070573; GO:0070821; GO:0090102; GO:0097038; GO:0097060; GO:0097197; GO:0098696; GO:0098978; GO:0099173; GO:0099175; GO:0140249; GO:1901342; GO:1901998; GO:1902945 9723 FUN_039596 0 0 0 0 18 NA NA NA NA NA NA NA 9724 FUN_039597 9 0 0 18 0 NA NA NA NA NA NA NA 9725 FUN_039594 46 27 139 0 128 NA NA NA NA NA NA NA 9726 FUN_039595 0 0 0 22 0 NA NA NA NA NA NA NA 9727 FUN_039592 0 0 0 0 8 NA NA NA NA NA NA NA 9728 FUN_039591 0 0 16 0 0 NA NA NA NA NA NA NA 9729 FUN_015539 15 0 0 0 40 NA NA NA NA NA NA NA 9730 FUN_039599 0 1 9 0 112 NA NA NA NA NA NA NA 9731 FUN_008245 167651 121265 116117 83927 30337 ptg000002l:9629656-9630166 Q9D119 6.85e-22 Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1) Mus musculus (Mouse) NA GO:0004864; GO:0019902 9732 FUN_020598 0 0 0 0 52 NA NA NA NA NA NA NA 9733 FUN_031033 0 0 0 0 49 NA NA NA NA NA NA NA 9734 FUN_031032 0 0 0 17 0 NA NA NA NA NA NA NA 9735 FUN_039622 0 66 47 0 49 NA NA NA NA NA NA NA 9736 FUN_039623 0 0 0 25 62 NA NA NA NA NA NA NA 9737 FUN_031039 0 0 0 0 9 NA NA NA NA NA NA NA 9738 FUN_031038 148 0 60 0 113 NA NA NA NA NA NA NA 9739 FUN_039626 0 0 0 0 6 NA NA NA NA NA NA NA 9740 FUN_008325 397 213 228 1118 618 ptg000002l:10312872-10331638 B3EWY9 5.56e-22 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 9741 FUN_008324 53 26 32 102 150 NA NA NA NA NA NA NA 9742 FUN_008327 49 9 23 0 36 NA NA NA NA NA NA NA 9743 FUN_027648 92 124 29 107 60 NA NA NA NA NA NA NA 9744 FUN_006784 28 1415 13 168 57 NA NA NA NA NA NA NA 9745 FUN_036029 5151 5441 1630 3529 2428 ptg000025l:14655129-14666587 P37879 1.59e-21 Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430] GO:0003676; GO:0003877; GO:0004824; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006430; GO:0015966; GO:0017101 9746 FUN_036029 5151 5441 1630 3529 2428 ptg000025l:14655129-14666587 P37879 1.59e-21 Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) diadenosine tetraphosphate biosynthetic process [GO:0015966]; lysyl-tRNA aminoacylation [GO:0006430] GO:0003676; GO:0003877; GO:0004824; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0005886; GO:0006430; GO:0015966; GO:0017101 9747 FUN_036028 1896 1498 436 903 1130 NA NA NA NA NA NA NA 9748 FUN_036023 0 25 12 11 19 NA NA NA NA NA NA NA 9749 FUN_036022 1133 368 478 1037 729 ptg000025l:14596023-14601256 O42430 5.23e-84 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 9750 FUN_036021 743 508 667 515 312 NA NA NA NA NA NA NA 9751 FUN_036020 378 110 172 112 209 NA NA NA NA NA NA NA 9752 FUN_036027 9328 7497 3941 5868 3657 NA NA NA NA NA NA NA 9753 FUN_036026 465 250 261 293 400 ptg000025l:14626566-14631249 Q28FE8 1.19e-35 tRNA-specific adenosine deaminase 1 (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA processing [GO:0008033] GO:0003723; GO:0008033; GO:0008251; GO:0046872 9754 FUN_036025 281 377 233 200 191 NA NA NA NA NA NA NA 9755 FUN_036024 181 168 143 246 201 NA NA NA NA NA NA NA 9756 FUN_006071 745 674 399 524 719 ptg000001l:7478890-7501780 P20825 2.57e-71 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 9757 FUN_006070 7 0 0 0 0 NA NA NA NA NA NA NA 9758 FUN_006074 0 35 0 0 40 NA NA NA NA NA NA NA 9759 FUN_004493 56 18 32 74 79 NA NA NA NA NA NA NA 9760 FUN_003440 8 2 1 4 4 NA NA NA NA NA NA NA 9761 FUN_003443 0 0 9 1 0 NA NA NA NA NA NA NA 9762 FUN_026996 99 294 36 11 89 NA NA NA NA NA NA NA 9763 FUN_026994 0 0 0 0 15 NA NA NA NA NA NA NA 9764 FUN_004490 0 42 26 20 23 NA NA NA NA NA NA NA 9765 FUN_026992 59 0 18 0 140 NA NA NA NA NA NA NA 9766 FUN_004497 26 62 14 30 28 NA NA NA NA NA NA NA 9767 FUN_026998 0 0 20 0 0 NA NA NA NA NA NA NA 9768 FUN_026999 0 0 0 16 0 NA NA NA NA NA NA NA 9769 FUN_037082 821 784 510 1180 1164 NA NA NA NA NA NA NA 9770 FUN_037083 1687 1701 934 1642 775 NA NA NA NA NA NA NA 9771 FUN_037080 428 235 132 255 220 ptg000026l:5454828-5456518 Q5I0J5 3.15e-44 MIT domain-containing protein 1 Rattus norvegicus (Rat) midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091] GO:0000281; GO:0019898; GO:0019904; GO:0030496; GO:0031902; GO:0032091; GO:0035091; GO:0042802; GO:0061952 9772 FUN_037080 428 235 132 255 220 ptg000026l:5454828-5456518 Q5I0J5 3.14e-27 MIT domain-containing protein 1 Rattus norvegicus (Rat) midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; negative regulation of protein binding [GO:0032091] GO:0000281; GO:0019898; GO:0019904; GO:0030496; GO:0031902; GO:0032091; GO:0035091; GO:0042802; GO:0061952 9773 FUN_037081 0 0 0 13 2 ptg000026l:5462998-5464264 Q7LGC8 3.68e-27 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 9774 FUN_037086 3797 1468 839 2968 850 NA NA NA NA NA NA NA 9775 FUN_037087 3108 1994 2071 3896 3303 NA NA NA NA NA NA NA 9776 FUN_037084 1382 1642 760 1799 1237 NA NA NA NA NA NA NA 9777 FUN_037085 314 233 206 360 422 NA NA NA NA NA NA NA 9778 FUN_024452 782 565 343 463 441 NA NA NA NA NA NA NA 9779 FUN_037088 1176 437 548 1129 835 NA NA NA NA NA NA NA 9780 FUN_037089 2484 889 1006 2687 1967 ptg000026l:5616705-5625109 A0A8M1NHK4 7.16e-92 RNA-binding protein 47 (RNA-binding motif protein 47) Danio rerio (Zebrafish) (Brachydanio rerio) antiviral innate immune response [GO:0140374]; lysosomal protein catabolic process [GO:1905146] GO:0003723; GO:0005634; GO:0005764; GO:0140374; GO:1905146 9781 FUN_040478 577 599 486 785 592 NA NA NA NA NA NA NA 9782 FUN_030854 0 0 0 0 9 NA NA NA NA NA NA NA 9783 FUN_030851 0 0 3 0 7 NA NA NA NA NA NA NA 9784 FUN_030852 0 3 3 0 30 NA NA NA NA NA NA NA 9785 FUN_004509 2452 2159 1247 2926 1668 NA NA NA NA NA NA NA 9786 FUN_004508 1302 783 442 920 410 ntLink_8:23866876-23871344 H9JW43 2.31e-34 Chitin deacetylase 8 (BmCDA8) (EC 3.5.1.41) (Chitin deacetylase 17) Bombyx mori (Silk moth) chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004099; GO:0005615; GO:0006032; GO:0008270 9787 FUN_004505 1698 1556 636 1713 2230 NA NA NA NA NA NA NA 9788 FUN_004504 40 29 27 13 190 NA NA NA NA NA NA NA 9789 FUN_004506 3779 2889 1209 1965 1020 ntLink_8:23863649-23864594 Q8BYK4 3.66e-94 Retinol dehydrogenase 12 (EC 1.1.1.300) Mus musculus (Mouse) cellular detoxification of aldehyde [GO:0110095]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0001917; GO:0004745; GO:0007601; GO:0042572; GO:0052650; GO:0102354; GO:0110095 9790 FUN_004501 368 194 153 228 226 ntLink_8:23803488-23817114 Q9H583 2.65e-71 HEAT repeat-containing protein 1 (Protein BAP28) (U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1, N-terminally processed] Homo sapiens (Human) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943] GO:0000462; GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005739; GO:0016020; GO:0030515; GO:0030686; GO:0032040; GO:0034455; GO:0045943; GO:2000234 9791 FUN_004500 2573 2057 1288 1396 1566 NA NA NA NA NA NA NA 9792 FUN_004503 18 3 36 20 46 NA NA NA NA NA NA NA 9793 FUN_004502 1725 1174 627 1251 1484 NA NA NA NA NA NA NA 9794 FUN_007852 543 302 309 358 312 ptg000002l:5473953-5476796 A5PJS2 7.33e-33 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (EC 1.3.1.22) (SR type 1) (Steroid 5-alpha-reductase 1) (S5AR 1) Bos taurus (Bovine) androgen biosynthetic process [GO:0006702]; cell differentiation [GO:0030154]; sex differentiation [GO:0007548]; steroid biosynthetic process [GO:0006694] GO:0003865; GO:0005789; GO:0006694; GO:0006702; GO:0007548; GO:0016491; GO:0030154; GO:0047751; GO:0050213 9795 FUN_007853 131 87 28 120 90 ptg000002l:5477635-5480635 A0A2B4RP11 4.84e-21 NA NA NA NA 9796 FUN_007850 100 54 30 133 54 NA NA NA NA NA NA NA 9797 FUN_007851 177 363 166 170 256 NA NA NA NA NA NA NA 9798 FUN_007856 1486 1212 637 1171 637 NA NA NA NA NA NA NA 9799 FUN_007857 5499 5477 2428 3557 2296 NA NA NA NA NA NA NA 9800 FUN_007854 1288 931 725 955 1042 NA NA NA NA NA NA NA 9801 FUN_007855 0 0 6 0 18 NA NA NA NA NA NA NA 9802 FUN_007858 545 872 454 442 230 NA NA NA NA NA NA NA 9803 FUN_007859 3324 4337 1858 3579 1081 ptg000002l:5512960-5515486 Q9BUX1 2.19e-22 Glutathione-specific gamma-glutamylcyclotransferase 1 (Gamma-GCG 1) (EC 4.3.2.7) (Blocks Notch protein) (Botch) (Cation transport regulator-like protein 1) Homo sapiens (Human) glutathione biosynthetic process [GO:0006750]; glutathione catabolic process [GO:0006751]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of protein processing [GO:0010955]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; response to unfolded protein [GO:0006986] GO:0003839; GO:0005112; GO:0005737; GO:0005802; GO:0005829; GO:0006750; GO:0006751; GO:0006986; GO:0007219; GO:0010955; GO:0022008; GO:0045746; GO:0061928; GO:0070059 9804 FUN_018662 847 87 388 3 897 NA NA NA NA NA NA NA 9805 FUN_006433 14885 3598 4724 3195 2220 ptg000001l:12392425-12393044 P35061 3.63e-64 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9806 FUN_033509 10039 11035 5482 9297 3496 NA NA NA NA NA NA NA 9807 FUN_033508 4698 5041 3309 5096 2364 NA NA NA NA NA NA NA 9808 FUN_008496 1068 1104 745 1833 949 ptg000002l:12222440-12223622 P58308 7.28e-23 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 9809 FUN_033503 0 0 0 0 11 ptg000023l:42664916-42667028 C0H692 1.29e-28 Small cysteine-rich protein 3 (Amil-SCRiP3) (SCRiP3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 9810 FUN_033503 0 0 0 0 11 ptg000023l:42664916-42667028 C0H692 1.29e-28 Small cysteine-rich protein 3 (Amil-SCRiP3) (SCRiP3) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 9811 FUN_033502 83 34 148 129 80 NA NA NA NA NA NA NA 9812 FUN_033507 1802 5076 7512 11431 988 NA NA NA NA NA NA NA 9813 FUN_006431 1387 419 797 508 329 NA NA NA NA NA NA NA 9814 FUN_033505 19 0 14 0 48 NA NA NA NA NA NA NA 9815 FUN_006437 10114 10476 3589 8477 9773 ptg000001l:12429565-12437245 P29145 3.91e-61 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 9816 FUN_006437 10114 10476 3589 8477 9773 ptg000001l:12429565-12437245 P29145 2.59e-25 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 9817 FUN_008492 34 11 0 20 13 ptg000002l:12185232-12185592 Q8K1T0 2.63e-29 Transmembrane protease serine 3 (EC 3.4.21.-) Mus musculus (Mouse) cellular sodium ion homeostasis [GO:0006883]; proteolysis [GO:0006508]; sensory perception of sound [GO:0007605] GO:0004252; GO:0005044; GO:0005783; GO:0005789; GO:0006508; GO:0006883; GO:0007605; GO:0017080; GO:0043025 9818 FUN_008491 0 0 0 0 54 NA NA NA NA NA NA NA 9819 FUN_008490 4118 2722 2596 3941 2944 ptg000002l:12159703-12181458 Q6A070 5.04e-85 TOG array regulator of axonemal microtubules protein 1 (Crescerin-1) (Protein FAM179B) Mus musculus (Mouse) axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle assembly [GO:0090307]; non-motile cilium assembly [GO:1905515]; positive regulation of microtubule polymerization [GO:0031116] GO:0000226; GO:0005815; GO:0005876; GO:0005881; GO:0005929; GO:0005930; GO:0008017; GO:0031116; GO:0035082; GO:0036064; GO:0060271; GO:0072686; GO:0090307; GO:1905515 9820 FUN_040006 0 0 0 0 6 NA NA NA NA NA NA NA 9821 FUN_035908 4156 2693 859 2072 1620 NA NA NA NA NA NA NA 9822 FUN_035905 372 535 657 724 534 NA NA NA NA NA NA NA 9823 FUN_035904 470 602 325 510 311 NA NA NA NA NA NA NA 9824 FUN_035907 3756 2630 1223 2838 2285 ptg000025l:13209526-13217729 Q62698 2.25e-27 Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55) Rattus norvegicus (Rat) cellular response to nerve growth factor stimulus [GO:1990090]; centrosome localization [GO:0051642]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based movement [GO:0007018] GO:0000226; GO:0000776; GO:0005524; GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0030286; GO:0042802; GO:0045504; GO:0051642; GO:1990090 9825 FUN_035907 3756 2630 1223 2838 2285 ptg000025l:13209526-13217729 Q62698 2.25e-27 Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55) Rattus norvegicus (Rat) cellular response to nerve growth factor stimulus [GO:1990090]; centrosome localization [GO:0051642]; microtubule cytoskeleton organization [GO:0000226]; microtubule-based movement [GO:0007018] GO:0000226; GO:0000776; GO:0005524; GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0030286; GO:0042802; GO:0045504; GO:0051642; GO:1990090 9826 FUN_035906 239 599 220 360 259 NA NA NA NA NA NA NA 9827 FUN_035901 2888 2470 1638 2114 1394 NA NA NA NA NA NA NA 9828 FUN_035900 910 683 410 683 947 NA NA NA NA NA NA NA 9829 FUN_035903 1198 671 940 1322 1702 ptg000025l:13123631-13143389 Q99315 1.24e-84 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 9830 FUN_035902 809 792 415 536 552 ptg000025l:13122233-13123356 Q9JJ94 4.4e-25 Microtubule nucleation factor SSNA1 (Sjoegren syndrome nuclear autoantigen 1 homolog) Mus musculus (Mouse) axon arborization [GO:0140060]; axon extension [GO:0048675]; axonogenesis [GO:0007409]; cell cycle [GO:0007049]; cell division [GO:0051301]; ciliary receptor clustering involved in smoothened signaling pathway [GO:0060830]; intraciliary transport [GO:0042073]; microtubule cytoskeleton organization [GO:0000226]; microtubule nucleation [GO:0007020] GO:0000226; GO:0005634; GO:0005813; GO:0005814; GO:0005930; GO:0007020; GO:0007049; GO:0007409; GO:0008017; GO:0030424; GO:0030496; GO:0031514; GO:0036064; GO:0042073; GO:0042802; GO:0043621; GO:0048675; GO:0051301; GO:0060830; GO:0099512; GO:0140060 9831 FUN_016272 4 0 5 4 17 NA NA NA NA NA NA NA 9832 FUN_016273 0 0 23 0 0 NA NA NA NA NA NA NA 9833 FUN_016279 1747 2054 1375 2905 2372 NA NA NA NA NA NA NA 9834 FUN_018409 112 115 35 272 258 NA NA NA NA NA NA NA 9835 FUN_018408 36 2 0 13 46 NA NA NA NA NA NA NA 9836 FUN_018401 187 179 82 133 541 NA NA NA NA NA NA NA 9837 FUN_018400 1050 1067 927 1414 1906 NA NA NA NA NA NA NA 9838 FUN_018403 2023 510 1225 824 1043 ptg000012l:8902796-8909366 Q28811 5.35e-30 Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) (DNA photolyase) (Photoreactivating enzyme) Potorous tridactylus (Potoroo) DNA repair [GO:0006281] GO:0003677; GO:0003904; GO:0006281 9839 FUN_018402 788 550 640 1432 1320 NA NA NA NA NA NA NA 9840 FUN_018405 1955 1655 1081 1974 1174 NA NA NA NA NA NA NA 9841 FUN_018404 1375 699 836 813 880 ptg000012l:8911572-8923841 Q9Y4C4 1.32e-33 Malignant fibrous histiocytoma-amplified sequence 1 (Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1) Homo sapiens (Human) erythrocyte differentiation [GO:0030218]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of inflammatory response [GO:0050728]; negative regulation of protein dephosphorylation [GO:0035308]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of JNK cascade [GO:0046330]; positive regulation of p38MAPK cascade [GO:1900745]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of toll-like receptor 2 signaling pathway [GO:0034137]; regulation of macrophage activation [GO:0043030]; regulation of toll-like receptor signaling pathway [GO:0034121] GO:0005525; GO:0005737; GO:0006954; GO:0030218; GO:0031625; GO:0034121; GO:0034136; GO:0034137; GO:0034144; GO:0035308; GO:0043030; GO:0045087; GO:0046330; GO:0050728; GO:0051721; GO:0051897; GO:0070374; GO:1900181; GO:1900745 9842 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 5e-52 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9843 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 1.04e-51 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9844 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 2.34e-51 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9845 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 1.29e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9846 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 1.63e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9847 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 2.85e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9848 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 5.63e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9849 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 7.85e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9850 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 2e-49 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9851 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 3.39e-49 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9852 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 4.99e-46 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9853 FUN_018407 1621 710 1092 897 785 ptg000012l:8961907-8983966 Q7Z494 4.16e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 9854 FUN_012445 335 25 242 136 92 ptg000008l:9018453-9023789 Q0EEE2 3.15e-35 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 9855 FUN_012445 335 25 242 136 92 ptg000008l:9018453-9023789 Q0EEE2 9.57e-21 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 9856 FUN_012444 0 18 0 19 0 NA NA NA NA NA NA NA 9857 FUN_012443 0 31 0 25 0 NA NA NA NA NA NA NA 9858 FUN_012442 10 843 0 1144 1006 ptg000008l:8976738-8990619 A0A0A2JW91 1.14e-130 Highly reducing polyketide synthase cnsI (EC 2.3.1.-) (Communesin biosynthesis cluster protein I) Penicillium expansum (Blue mold rot fungus) fatty acid biosynthetic process [GO:0006633]; heterocycle metabolic process [GO:0046483]; organic cyclic compound metabolic process [GO:1901360]; secondary metabolite biosynthetic process [GO:0044550] GO:0004315; GO:0006633; GO:0016491; GO:0031177; GO:0044550; GO:0046483; GO:1901360 9859 FUN_012441 4 579 0 443 363 NA NA NA NA NA NA NA 9860 FUN_012440 0 103 0 129 137 ptg000008l:8964560-8969422 Q0EEE2 4.23e-32 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 9861 FUN_012449 18 2 10 2 37 NA NA NA NA NA NA NA 9862 FUN_012448 23 35 29 10 92 NA NA NA NA NA NA NA 9863 FUN_016537 7 25 4 2 35 NA NA NA NA NA NA NA 9864 FUN_016536 3 5 15 0 54 NA NA NA NA NA NA NA 9865 FUN_016535 2 11 8 15 27 NA NA NA NA NA NA NA 9866 FUN_006810 45 26 2 80 13 NA NA NA NA NA NA NA 9867 FUN_016530 28 76 60 106 121 ptg000011l:4405540-4411555 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9868 FUN_016530 28 76 60 106 121 ptg000011l:4405540-4411555 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9869 FUN_016530 28 76 60 106 121 ptg000011l:4405540-4411555 Q96AY4 6.07e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9870 FUN_016530 28 76 60 106 121 ptg000011l:4405540-4411555 Q96AY4 1.94e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9871 FUN_006819 0 0 0 23 3 NA NA NA NA NA NA NA 9872 FUN_006818 33 49 23 368 58 NA NA NA NA NA NA NA 9873 FUN_016538 60 53 52 83 116 ptg000011l:4478692-4483849 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9874 FUN_016538 60 53 52 83 116 ptg000011l:4478692-4483849 Q96AY4 3.81e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9875 FUN_016538 60 53 52 83 116 ptg000011l:4478692-4483849 Q96AY4 3.46e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9876 FUN_016538 60 53 52 83 116 ptg000011l:4478692-4483849 Q96AY4 3.19e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9877 FUN_004145 3 19 7 37 1 NA NA NA NA NA NA NA 9878 FUN_004140 3381 2335 1571 2827 1941 NA NA NA NA NA NA NA 9879 FUN_035013 587 159 126 403 327 ptg000025l:2760177-2765085 Q9GV16 2.25e-172 Endoglycoceramidase (EGCase) (EC 3.2.1.123) (Glycosphingolipid-specific enzyme) (GSL-specific enzyme) Cyanea nozakii (Jellyfish) carbohydrate derivative catabolic process [GO:1901136]; cellulose catabolic process [GO:0030245]; lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0030245; GO:0042151; GO:0047876; GO:1901136 9880 FUN_035012 1773 2802 872 1423 1012 NA NA NA NA NA NA NA 9881 FUN_035011 2840 2561 2024 2459 1915 ptg000025l:2739221-2748188 Q9PTY5 1.37e-21 Ran-binding protein 9 (RanBP9) (Ran-binding protein M) (RanBPM) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:0005886 9882 FUN_035010 5532 7666 2125 3456 2104 NA NA NA NA NA NA NA 9883 FUN_035017 159 103 52 262 146 NA NA NA NA NA NA NA 9884 FUN_035015 224 588 146 502 456 NA NA NA NA NA NA NA 9885 FUN_035019 294 83 222 434 237 NA NA NA NA NA NA NA 9886 FUN_003365 35 0 17 0 91 NA NA NA NA NA NA NA 9887 FUN_003366 0 0 54 134 13 NA NA NA NA NA NA NA 9888 FUN_028127 0 0 6 0 0 NA NA NA NA NA NA NA 9889 FUN_028121 12 0 0 0 0 NA NA NA NA NA NA NA 9890 FUN_028120 315 130 75 276 177 NA NA NA NA NA NA NA 9891 FUN_028123 11 39 28 13 44 NA NA NA NA NA NA NA 9892 FUN_028122 8783 5214 5557 8010 6393 NA NA NA NA NA NA NA 9893 FUN_039790 2777 996 715 2741 1663 NA NA NA NA NA NA NA 9894 FUN_039791 2891 3289 1827 1048 1139 NA NA NA NA NA NA NA 9895 FUN_043342 252 461 47 144 208 NA NA NA NA NA NA NA 9896 FUN_043343 959 1212 164 385 271 ptg000047l:7291320-7298464 Q99MQ3 9.36e-23 Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1) Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; catecholamine secretion [GO:0050432]; cellular response to hydrogen sulfide [GO:1904881]; cellular response to hypoxia [GO:0071456]; cellular response to oxidative stress [GO:0034599]; cellular response to toxic substance [GO:0097237]; dopamine secretion [GO:0014046]; establishment of localization in cell [GO:0051649]; establishment of protein localization to mitochondrion [GO:0072655]; hemopoiesis [GO:0030097]; intracellular signal transduction [GO:0035556]; maintenance of protein location in mitochondrion [GO:0072656]; mitochondrion organization [GO:0007005]; mitochondrion to lysosome transport [GO:0099074]; mitophagy [GO:0000423]; negative regulation of apoptotic process [GO:0043066]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [GO:1903384]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide [GO:1903751]; negative regulation of macroautophagy [GO:0016242]; negative regulation of mitochondrial fission [GO:0090258]; negative regulation of mitophagy [GO:1901525]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of catecholamine secretion [GO:0033605]; positive regulation of cristae formation [GO:1903852]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; positive regulation of mitochondrial electron transport, NADH to ubiquinone [GO:1902958]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of NMDA glutamate receptor activity [GO:1904783]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to oxidative stress [GO:1900407]; regulation of hydrogen peroxide metabolic process [GO:0010310]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrion organization [GO:0010821]; regulation of neuron apoptotic process [GO:0043523]; regulation of oxidative phosphorylation [GO:0002082]; regulation of protein targeting to mitochondrion [GO:1903214]; regulation of protein ubiquitination [GO:0031396]; regulation of protein-containing complex assembly [GO:0043254]; regulation of reactive oxygen species metabolic process [GO:2000377]; respiratory electron transport chain [GO:0022904]; response to ischemia [GO:0002931]; response to oxidative stress [GO:0006979] GO:0000287; GO:0000422; GO:0000423; GO:0000785; GO:0001934; GO:0002020; GO:0002082; GO:0002931; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005758; GO:0005783; GO:0005829; GO:0005856; GO:0006468; GO:0006979; GO:0007005; GO:0010310; GO:0010629; GO:0010821; GO:0010857; GO:0014046; GO:0016020; GO:0016239; GO:0016242; GO:0016301; GO:0016567; GO:0018105; GO:0022904; GO:0030097; GO:0030424; GO:0030426; GO:0031396; GO:0031625; GO:0032226; GO:0033138; GO:0033603; GO:0033605; GO:0034599; GO:0035307; GO:0035556; GO:0036289; GO:0042981; GO:0043066; GO:0043123; GO:0043254; GO:0043422; GO:0043523; GO:0043524; GO:0044297; GO:0044877; GO:0045727; GO:0048471; GO:0050432; GO:0050821; GO:0051091; GO:0051649; GO:0051881; GO:0055131; GO:0071456; GO:0072655; GO:0072656; GO:0090141; GO:0090200; GO:0090258; GO:0097237; GO:0097449; GO:0098779; GO:0099074; GO:0106310; GO:1900407; GO:1901215; GO:1901525; GO:1901727; GO:1902902; GO:1902958; GO:1903202; GO:1903214; GO:1903298; GO:1903384; GO:1903751; GO:1903852; GO:1904783; GO:1904841; GO:1904881; GO:1904925; GO:2000377; GO:2000378; GO:2001243 9897 FUN_043340 45 3 0 5 0 NA NA NA NA NA NA NA 9898 FUN_043341 0 62 0 102 60 NA NA NA NA NA NA NA 9899 FUN_043346 1643 52 47 138 102 NA NA NA NA NA NA NA 9900 FUN_040349 0 0 0 0 10 NA NA NA NA NA NA NA 9901 FUN_043344 278 91 35 42 24 NA NA NA NA NA NA NA 9902 FUN_043345 467 197 178 574 780 NA NA NA NA NA NA NA 9903 FUN_039794 1118 739 378 935 731 NA NA NA NA NA NA NA 9904 FUN_043348 2359 1683 1693 2567 2543 NA NA NA NA NA NA NA 9905 FUN_043349 3304 1899 2191 6360 5808 NA NA NA NA NA NA NA 9906 FUN_039796 161 173 179 0 69 NA NA NA NA NA NA NA 9907 FUN_041274 86 108 130 123 197 NA NA NA NA NA NA NA 9908 FUN_041275 226 107 69 193 147 NA NA NA NA NA NA NA 9909 FUN_041277 284 84 64 433 206 NA NA NA NA NA NA NA 9910 FUN_028693 26 17 9 16 70 ptg000022l:2777302-2783722 Q96AY4 1.91e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9911 FUN_028693 26 17 9 16 70 ptg000022l:2777302-2783722 Q96AY4 1.92e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9912 FUN_028693 26 17 9 16 70 ptg000022l:2777302-2783722 Q96AY4 1.93e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9913 FUN_028693 26 17 9 16 70 ptg000022l:2777302-2783722 Q96AY4 8.76e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9914 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 4.04e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9915 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 2.33e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9916 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 2.41e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9917 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 2.45e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9918 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 6.06e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9919 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 2.51e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9920 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 1.31e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9921 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 2.36e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9922 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 3.04e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9923 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 6.14e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9924 FUN_028691 30 0 22 17 2 ptg000022l:2731184-2739905 Q96AY4 2.09e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 9925 FUN_041273 24 138 14 18 47 NA NA NA NA NA NA NA 9926 FUN_013318 2 0 0 8 0 NA NA NA NA NA NA NA 9927 FUN_013319 0 0 0 38 15 NA NA NA NA NA NA NA 9928 FUN_028698 2097 3957 9 6 1620 NA NA NA NA NA NA NA 9929 FUN_043146 750 619 470 1058 555 NA NA NA NA NA NA NA 9930 FUN_043692 0 0 8 0 0 NA NA NA NA NA NA NA 9931 FUN_043698 0 0 0 12 0 NA NA NA NA NA NA NA 9932 FUN_043699 8 0 13 0 17 NA NA NA NA NA NA NA 9933 FUN_003948 8 1 12 0 18 NA NA NA NA NA NA NA 9934 FUN_041188 3229 11289 2463 8180 6240 NA NA NA NA NA NA NA 9935 FUN_003944 27 0 42 16 155 NA NA NA NA NA NA NA 9936 FUN_003945 23 88 16 218 20 NA NA NA NA NA NA NA 9937 FUN_003946 3 0 24 1 78 NA NA NA NA NA NA NA 9938 FUN_041185 0 0 0 0 11 NA NA NA NA NA NA NA 9939 FUN_041182 7 6 0 0 2 NA NA NA NA NA NA NA 9940 FUN_003942 0 0 0 0 27 NA NA NA NA NA NA NA 9941 FUN_003943 0 15 4 34 13 NA NA NA NA NA NA NA 9942 FUN_009045 0 0 0 11 23 NA NA NA NA NA NA NA 9943 FUN_009044 3128 1149 914 2080 1408 ptg000004l:1915228-1942563 P56941 1.13e-65 NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) Sus scrofa (Pig) bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intestinal cholesterol absorption [GO:0030299]; intracellular cholesterol transport [GO:0032367]; lysosomal transport [GO:0007041]; negative regulation of TORC1 signaling [GO:1904262]; protein glycosylation [GO:0006486]; sterol transport [GO:0015918] GO:0005319; GO:0005576; GO:0005635; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0006486; GO:0007041; GO:0008203; GO:0008206; GO:0015485; GO:0015918; GO:0016020; GO:0030299; GO:0030301; GO:0031902; GO:0032367; GO:0032934; GO:0042632; GO:0048471; GO:1904262 9944 FUN_009044 3128 1149 914 2080 1408 ptg000004l:1915228-1942563 P56941 2.01e-32 NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) Sus scrofa (Pig) bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intestinal cholesterol absorption [GO:0030299]; intracellular cholesterol transport [GO:0032367]; lysosomal transport [GO:0007041]; negative regulation of TORC1 signaling [GO:1904262]; protein glycosylation [GO:0006486]; sterol transport [GO:0015918] GO:0005319; GO:0005576; GO:0005635; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0006486; GO:0007041; GO:0008203; GO:0008206; GO:0015485; GO:0015918; GO:0016020; GO:0030299; GO:0030301; GO:0031902; GO:0032367; GO:0032934; GO:0042632; GO:0048471; GO:1904262 9945 FUN_009044 3128 1149 914 2080 1408 ptg000004l:1915228-1942563 P56941 1.76e-26 NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein) Sus scrofa (Pig) bile acid metabolic process [GO:0008206]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; intestinal cholesterol absorption [GO:0030299]; intracellular cholesterol transport [GO:0032367]; lysosomal transport [GO:0007041]; negative regulation of TORC1 signaling [GO:1904262]; protein glycosylation [GO:0006486]; sterol transport [GO:0015918] GO:0005319; GO:0005576; GO:0005635; GO:0005764; GO:0005765; GO:0005783; GO:0005886; GO:0006486; GO:0007041; GO:0008203; GO:0008206; GO:0015485; GO:0015918; GO:0016020; GO:0030299; GO:0030301; GO:0031902; GO:0032367; GO:0032934; GO:0042632; GO:0048471; GO:1904262 9946 FUN_009043 4349 3813 1973 3020 1960 NA NA NA NA NA NA NA 9947 FUN_009042 568 652 71 355 428 ptg000004l:1898095-1901319 O95551 7.65e-47 Tyrosyl-DNA phosphodiesterase 2 (Tyr-DNA phosphodiesterase 2) (hTDP2) (EC 3.1.4.-) (5'-tyrosyl-DNA phosphodiesterase) (5'-Tyr-DNA phosphodiesterase) (ETS1-associated protein 2) (ETS1-associated protein II) (EAPII) (TRAF and TNF receptor-associated protein) (Tyrosyl-RNA phosphodiesterase) (VPg unlinkase) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; double-strand break repair [GO:0006302]; neuron development [GO:0048666] GO:0000287; GO:0003697; GO:0003714; GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0007166; GO:0016235; GO:0016604; GO:0016605; GO:0030145; GO:0036317; GO:0048666; GO:0070260 9948 FUN_009041 654 617 309 971 1419 NA NA NA NA NA NA NA 9949 FUN_009040 208 185 53 130 125 NA NA NA NA NA NA NA 9950 FUN_002019 0 0 0 0 11 NA NA NA NA NA NA NA 9951 FUN_009049 234 79 45 317 187 NA NA NA NA NA NA NA 9952 FUN_009048 45 39 11 24 65 NA NA NA NA NA NA NA 9953 FUN_032138 59 26 59 154 73 NA NA NA NA NA NA NA 9954 FUN_040637 7 3 2 8 6 NA NA NA NA NA NA NA 9955 FUN_012943 22 14 10 0 9 NA NA NA NA NA NA NA 9956 FUN_012946 0 0 5 2 11 NA NA NA NA NA NA NA 9957 FUN_012947 0 0 0 0 7 NA NA NA NA NA NA NA 9958 FUN_012944 0 0 9 0 5 NA NA NA NA NA NA NA 9959 FUN_012948 13 3 37 1 60 NA NA NA NA NA NA NA 9960 FUN_009955 0 22 8 0 0 NA NA NA NA NA NA NA 9961 FUN_009951 0 0 0 0 32 NA NA NA NA NA NA NA 9962 FUN_009959 33682 26613 12107 21549 12220 ptg000004l:13447203-13449129 Q5ZMD6 6.99e-21 Histone H2A.Z (H2A/z) Gallus gallus (Chicken) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 9963 FUN_032372 48 24 20 29 12 ptg000023l:31276655-31283818 Q04786 7.36e-36 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9964 FUN_032372 48 24 20 29 12 ptg000023l:31276655-31283818 Q04786 6.13e-26 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9965 FUN_032371 1681 363 502 690 523 ptg000023l:31255004-31264650 Q04786 2.73e-53 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9966 FUN_032371 1681 363 502 690 523 ptg000023l:31255004-31264650 Q04786 2.13e-28 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9967 FUN_032370 1457 976 644 1485 1035 ptg000023l:31244320-31253516 Q04786 2.09e-42 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9968 FUN_032370 1457 976 644 1485 1035 ptg000023l:31244320-31253516 Q04786 4.17e-22 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9969 FUN_032377 4799 4176 1016 3266 2896 NA NA NA NA NA NA NA 9970 FUN_032375 0 9 0 0 0 NA NA NA NA NA NA NA 9971 FUN_032374 0 0 0 7 0 ptg000023l:31287806-31291485 Q04786 4.52e-47 Beta-hexosaminidase (EC 3.2.1.52) (Beta-N-acetylhexosaminidase) (Chitobiase) (N-acetyl-beta-glucosaminidase) Vibrio vulnificus chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004563; GO:0006032; GO:0030247; GO:0102148 9972 FUN_032379 2295 2175 1622 2314 2471 ptg000023l:31319564-31329770 Q66I21 1.87e-25 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase family 8 member A1) Danio rerio (Zebrafish) (Brachydanio rerio) L-kynurenine catabolic process [GO:0097053]; liver development [GO:0001889]; retinoic acid metabolic process [GO:0042573] GO:0001758; GO:0001889; GO:0005737; GO:0016620; GO:0042573; GO:0047102; GO:0097053 9973 FUN_032378 8304 17491 7914 14289 10266 NA NA NA NA NA NA NA 9974 FUN_028909 17 49 45 71 105 NA NA NA NA NA NA NA 9975 FUN_028908 853 305 234 1105 521 NA NA NA NA NA NA NA 9976 FUN_028907 152 203 128 166 161 ptg000022l:5838007-5849508 Q54DD3 1.17e-44 Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT) Dictyostelium discoideum (Social amoeba) glycine decarboxylation via glycine cleavage system [GO:0019464] GO:0004047; GO:0005739; GO:0008483; GO:0019464 9977 FUN_028906 3409 2072 1406 2832 2226 NA NA NA NA NA NA NA 9978 FUN_028905 30 495 289 248 33 NA NA NA NA NA NA NA 9979 FUN_028904 21 16 9 5239 8 NA NA NA NA NA NA NA 9980 FUN_028903 281 665 409 653 180 NA NA NA NA NA NA NA 9981 FUN_028902 0 0 11 0 15 NA NA NA NA NA NA NA 9982 FUN_028901 24 0 0 9 16 NA NA NA NA NA NA NA 9983 FUN_028900 0 0 0 0 14 NA NA NA NA NA NA NA 9984 FUN_011209 2 3 0 0 12 NA NA NA NA NA NA NA 9985 FUN_011206 0 0 19 24 293 NA NA NA NA NA NA NA 9986 FUN_011207 0 0 19 0 80 NA NA NA NA NA NA NA 9987 FUN_011200 2 0 0 0 8 NA NA NA NA NA NA NA 9988 FUN_008608 0 0 0 0 33 NA NA NA NA NA NA NA 9989 FUN_008609 242 70 10 293 323 NA NA NA NA NA NA NA 9990 FUN_028762 73 51 75 56 193 ptg000022l:3627236-3633185 Q9Y6A2 2.57e-32 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 9991 FUN_008603 86 0 99 79 201 NA NA NA NA NA NA NA 9992 FUN_008601 83 34 65 237 109 NA NA NA NA NA NA NA 9993 FUN_008606 690 1702 152 610 509 NA NA NA NA NA NA NA 9994 FUN_008607 102 39 49 28 51 NA NA NA NA NA NA NA 9995 FUN_008604 3141 2280 2006 2621 1991 NA NA NA NA NA NA NA 9996 FUN_008605 3753 4639 1396 5620 3060 NA NA NA NA NA NA NA 9997 FUN_029058 57 301 187 410 315 NA NA NA NA NA NA NA 9998 FUN_029059 482 183 371 378 477 NA NA NA NA NA NA NA 9999 FUN_029052 320 10 121 276 529 NA NA NA NA NA NA NA 10000 FUN_029053 569 147 682 343 343 NA NA NA NA NA NA NA 10001 FUN_029050 1116 1544 639 882 790 NA NA NA NA NA NA NA 10002 FUN_029051 434 111 199 268 369 NA NA NA NA NA NA NA 10003 FUN_029056 1042 472 640 974 783 NA NA NA NA NA NA NA 10004 FUN_029057 3767 1689 2377 5498 3021 NA NA NA NA NA NA NA 10005 FUN_029054 1618 431 539 1521 1114 NA NA NA NA NA NA NA 10006 FUN_029055 66 33 94 66 63 NA NA NA NA NA NA NA 10007 FUN_039028 974 324 588 1180 21 NA NA NA NA NA NA NA 10008 FUN_039029 2026 941 824 1528 1621 NA NA NA NA NA NA NA 10009 FUN_039026 7 7 2 0 1 NA NA NA NA NA NA NA 10010 FUN_039027 0 0 0 0 14 NA NA NA NA NA NA NA 10011 FUN_039025 13 42 0 0 0 NA NA NA NA NA NA NA 10012 FUN_039022 0 0 19 2 6 NA NA NA NA NA NA NA 10013 FUN_036435 13 0 8 1 10 NA NA NA NA NA NA NA 10014 FUN_000292 1780 5174 378 6229 14874 NA NA NA NA NA NA NA 10015 FUN_020864 0 0 0 107 33 NA NA NA NA NA NA NA 10016 FUN_020865 9 0 17 0 97 NA NA NA NA NA NA NA 10017 FUN_020860 24 10 33 27 6 NA NA NA NA NA NA NA 10018 FUN_020861 109 28 132 69 585 NA NA NA NA NA NA NA 10019 FUN_020863 0 18 0 0 0 NA NA NA NA NA NA NA 10020 FUN_020868 0 12 0 0 0 NA NA NA NA NA NA NA 10021 FUN_020869 0 0 0 0 7 NA NA NA NA NA NA NA 10022 FUN_019538 0 0 4 3 65 NA NA NA NA NA NA NA 10023 FUN_010638 10224 17500 5013 10888 6762 ptg000007l:1080715-1084081 Q7LG56 1.35e-56 Ribonucleoside-diphosphate reductase subunit M2 B (EC 1.17.4.1) (TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2) Homo sapiens (Human) 2'-deoxyribonucleotide biosynthetic process [GO:0009265]; deoxyribonucleoside triphosphate metabolic process [GO:0009200]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA repair [GO:0006281]; DNA synthesis involved in DNA repair [GO:0000731]; kidney development [GO:0001822]; mitochondrial DNA replication [GO:0006264]; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator [GO:1902254]; positive regulation of G0 to G1 transition [GO:0070318]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; renal system process [GO:0003014]; response to amine [GO:0014075]; response to oxidative stress [GO:0006979]; ribonucleoside diphosphate metabolic process [GO:0009185] GO:0000731; GO:0001822; GO:0003014; GO:0004748; GO:0005654; GO:0005739; GO:0005829; GO:0005971; GO:0006264; GO:0006281; GO:0006979; GO:0009185; GO:0009200; GO:0009263; GO:0009265; GO:0010971; GO:0014075; GO:0042802; GO:0046872; GO:0070318; GO:1902254 10024 FUN_041332 0 1 0 14 0 NA NA NA NA NA NA NA 10025 FUN_010632 4736 2636 2374 4492 2012 NA NA NA NA NA NA NA 10026 FUN_010630 562 569 295 539 520 NA NA NA NA NA NA NA 10027 FUN_010631 1595 1506 760 960 829 NA NA NA NA NA NA NA 10028 FUN_010636 1148 675 421 792 1087 ptg000007l:1043102-1069020 P49746 8.28e-36 Thrombospondin-3 Homo sapiens (Human) bone trabecula formation [GO:0060346]; cell-matrix adhesion [GO:0007160]; growth plate cartilage development [GO:0003417]; ossification involved in bone maturation [GO:0043931] GO:0003417; GO:0005509; GO:0005576; GO:0007160; GO:0008201; GO:0043931; GO:0048471; GO:0060346; GO:0062023 10029 FUN_010637 7299 11958 7787 7758 3731 NA NA NA NA NA NA NA 10030 FUN_010634 493 199 355 506 274 NA NA NA NA NA NA NA 10031 FUN_010635 1922 664 824 1731 1645 ptg000007l:1014590-1035189 P49746 2e-31 Thrombospondin-3 Homo sapiens (Human) bone trabecula formation [GO:0060346]; cell-matrix adhesion [GO:0007160]; growth plate cartilage development [GO:0003417]; ossification involved in bone maturation [GO:0043931] GO:0003417; GO:0005509; GO:0005576; GO:0007160; GO:0008201; GO:0043931; GO:0048471; GO:0060346; GO:0062023 10032 FUN_008130 19 0 0 0 17 NA NA NA NA NA NA NA 10033 FUN_041339 0 0 0 45 0 NA NA NA NA NA NA NA 10034 FUN_012168 804 549 247 633 673 NA NA NA NA NA NA NA 10035 FUN_012169 4108 5046 2154 4087 2352 NA NA NA NA NA NA NA 10036 FUN_012164 66 27 41 123 92 NA NA NA NA NA NA NA 10037 FUN_012166 8324 5858 3519 5363 2495 NA NA NA NA NA NA NA 10038 FUN_012167 712 736 663 562 465 NA NA NA NA NA NA NA 10039 FUN_012160 885 1659 1113 1279 1666 NA NA NA NA NA NA NA 10040 FUN_012161 1126 924 728 1389 1489 NA NA NA NA NA NA NA 10041 FUN_038855 0 0 30 13 104 NA NA NA NA NA NA NA 10042 FUN_038856 0 0 0 0 30 NA NA NA NA NA NA NA 10043 FUN_038850 30 0 15 0 171 NA NA NA NA NA NA NA 10044 FUN_038851 0 1 0 9 8 NA NA NA NA NA NA NA 10045 FUN_038859 0 15 0 0 0 NA NA NA NA NA NA NA 10046 FUN_027849 3333 2316 1662 3118 2228 NA NA NA NA NA NA NA 10047 FUN_027848 88 62 0 0 0 NA NA NA NA NA NA NA 10048 FUN_027847 993 694 539 569 485 NA NA NA NA NA NA NA 10049 FUN_027845 4 40 4 0 153 NA NA NA NA NA NA NA 10050 FUN_027842 91 0 0 0 82 NA NA NA NA NA NA NA 10051 FUN_027841 3 15 1 8 1 NA NA NA NA NA NA NA 10052 FUN_027840 143 0 0 0 0 NA NA NA NA NA NA NA 10053 FUN_014643 1275 1006 603 1047 954 NA NA NA NA NA NA NA 10054 FUN_014642 90 115 30 53 98 ptg000009l:1787635-1789089 Q5XGY9 8.93e-26 Meiotic nuclear division protein 1 homolog Xenopus laevis (African clawed frog) reciprocal meiotic recombination [GO:0007131] GO:0003690; GO:0005634; GO:0007131 10055 FUN_014642 90 115 30 53 98 ptg000009l:1787635-1789089 Q5XGY9 1.16e-23 Meiotic nuclear division protein 1 homolog Xenopus laevis (African clawed frog) reciprocal meiotic recombination [GO:0007131] GO:0003690; GO:0005634; GO:0007131 10056 FUN_014641 1287 1301 872 1064 1010 NA NA NA NA NA NA NA 10057 FUN_014640 709 828 381 447 470 NA NA NA NA NA NA NA 10058 FUN_014647 3340 2437 1564 2107 1604 NA NA NA NA NA NA NA 10059 FUN_014646 5313 5814 3315 8855 9487 NA NA NA NA NA NA NA 10060 FUN_014645 1701 829 891 994 990 ptg000009l:1804536-1807215 A3KGZ2 4.41e-50 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005506; GO:0016705; GO:0031418; GO:0051213 10061 FUN_014645 1701 829 891 994 990 ptg000009l:1804536-1807215 A3KGZ2 4.09e-25 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 (EC 1.14.11.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005506; GO:0016705; GO:0031418; GO:0051213 10062 FUN_014644 726 325 415 513 558 NA NA NA NA NA NA NA 10063 FUN_014649 0 2 3 7 0 NA NA NA NA NA NA NA 10064 FUN_011732 0 0 18 0 26 NA NA NA NA NA NA NA 10065 FUN_000498 888 511 501 574 514 ntLink_6:3673365-3681443 Q58CW6 9.03e-30 Calcium-responsive transcription factor (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein) Bos taurus (Bovine) cellular response to calcium ion [GO:0071277]; positive regulation of transcription from RNA polymerase II promoter in response to calcium ion [GO:0061400] GO:0001228; GO:0003677; GO:0005634; GO:0061400; GO:0071277 10066 FUN_009568 0 13 0 0 32 NA NA NA NA NA NA NA 10067 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 7.35e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10068 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 1.58e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10069 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 3.6e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10070 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 4.86e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10071 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 3.6e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10072 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 8.98e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10073 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 8.98e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10074 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 2.86e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10075 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 3.02e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10076 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 1.26e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10077 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 1.34e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10078 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 2.36e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10079 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 2.75e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10080 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 3.87e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10081 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 9.17e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10082 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 9.31e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10083 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 1.9e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10084 FUN_009569 423 70 20 0 26 ptg000004l:8677642-8681346 Q96AY4 3.58e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10085 FUN_025999 269 100 78 218 175 ptg000020l:3129679-3132592 Q8BHB0 1.96e-24 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 10086 FUN_025998 658 199 283 257 316 ptg000020l:3104221-3107608 P59046 1.6e-39 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 10087 FUN_009564 43 0 0 0 0 ptg000004l:8619850-8625170 O00370 3.28e-27 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 10088 FUN_025996 143 90 54 88 79 ptg000020l:3034469-3036720 Q86W24 3.32e-32 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 10089 FUN_025996 143 90 54 88 79 ptg000020l:3034469-3036720 Q86W24 6.8e-25 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 10090 FUN_009566 70 238 164 182 182 NA NA NA NA NA NA NA 10091 FUN_025994 0 98 0 77 164 NA NA NA NA NA NA NA 10092 FUN_025993 51 13 36 176 47 ptg000020l:2974151-3014760 Q7RTR2 7.21e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10093 FUN_025992 697 108 111 508 81 ptg000020l:2969142-2973394 Q7RTR2 2.73e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10094 FUN_025991 545 204 222 346 86 ptg000020l:2949140-2955022 C3VPR6 6.38e-25 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 10095 FUN_025990 658 122 110 604 176 ptg000020l:2929602-2936609 Q7RTR2 1.15e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10096 FUN_000493 11 17 0 30 33 ntLink_6:3626920-3630476 Q9BWV3 1.03e-31 Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) (Testis development protein NYD-SP15) Homo sapiens (Human) cytidine deamination [GO:0009972]; DNA cytosine deamination [GO:0070383] GO:0004126; GO:0005634; GO:0005737; GO:0008270; GO:0009972; GO:0042803; GO:0061676; GO:0070383 10097 FUN_011739 850 747 366 980 462 NA NA NA NA NA NA NA 10098 FUN_019330 569 116 138 283 177 NA NA NA NA NA NA NA 10099 FUN_019331 4423 5887 2531 2921 2478 ptg000015l:1148112-1154016 Q8BH69 9.88e-53 Selenide, water dikinase 1 (EC 2.7.9.3) (Selenium donor protein 1) (Selenophosphate synthase 1) Mus musculus (Mouse) phosphorylation [GO:0016310]; selenocysteine biosynthetic process [GO:0016260] GO:0004756; GO:0005524; GO:0005737; GO:0005886; GO:0016260; GO:0016310; GO:0031965; GO:0042802; GO:0042803; GO:0046872; GO:0046982 10100 FUN_019331 4423 5887 2531 2921 2478 ptg000015l:1148112-1154016 Q8BH69 1.73e-33 Selenide, water dikinase 1 (EC 2.7.9.3) (Selenium donor protein 1) (Selenophosphate synthase 1) Mus musculus (Mouse) phosphorylation [GO:0016310]; selenocysteine biosynthetic process [GO:0016260] GO:0004756; GO:0005524; GO:0005737; GO:0005886; GO:0016260; GO:0016310; GO:0031965; GO:0042802; GO:0042803; GO:0046872; GO:0046982 10101 FUN_019332 214 116 313 743 295 ptg000015l:1160730-1164834 P06872 5.9e-30 Anionic trypsin (EC 3.4.21.4) Canis lupus familiaris (Dog) (Canis familiaris) collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0007586; GO:0030574 10102 FUN_019333 81 45 103 593 281 NA NA NA NA NA NA NA 10103 FUN_019334 1018 1224 1229 1895 1441 ptg000015l:1187106-1219583 P0CT39 7.92e-66 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 10104 FUN_019335 6570 3736 3072 4999 3696 NA NA NA NA NA NA NA 10105 FUN_019336 0 0 0 0 14 NA NA NA NA NA NA NA 10106 FUN_019337 0 185 44 217 37 NA NA NA NA NA NA NA 10107 FUN_026714 1167 1546 889 1670 1121 NA NA NA NA NA NA NA 10108 FUN_026715 14204 15886 10319 21594 11688 NA NA NA NA NA NA NA 10109 FUN_026716 27 0 0 0 0 NA NA NA NA NA NA NA 10110 FUN_026710 598 265 340 788 1100 NA NA NA NA NA NA NA 10111 FUN_026712 186 70 34 50 45 NA NA NA NA NA NA NA 10112 FUN_026713 6244 5453 3395 5268 3887 NA NA NA NA NA NA NA 10113 FUN_039819 2746 2149 1645 2980 3307 NA NA NA NA NA NA NA 10114 FUN_039818 1582 1717 416 553 351 ptg000031l:469151-472180 Q6DH69 9.02e-60 Fatty-acid amide hydrolase 2-A (EC 3.5.1.99) Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042] GO:0016020; GO:0016042; GO:0017064 10115 FUN_039818 1582 1717 416 553 351 ptg000031l:469151-472180 Q6DH69 2.72e-30 Fatty-acid amide hydrolase 2-A (EC 3.5.1.99) Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042] GO:0016020; GO:0016042; GO:0017064 10116 FUN_039817 2430 2092 1282 2522 1942 ptg000031l:451052-465083 P26640 1.98e-31 Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) Homo sapiens (Human) tRNA aminoacylation for protein translation [GO:0006418]; valyl-tRNA aminoacylation [GO:0006438] GO:0002161; GO:0004832; GO:0005524; GO:0005829; GO:0006418; GO:0006438 10117 FUN_039816 2856 1260 1575 3755 3891 ptg000031l:403748-448492 P41234 4.77e-37 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Mus musculus (Mouse) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to steroid hormone [GO:0048545]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512] GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0060049; GO:0061135; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 10118 FUN_039816 2856 1260 1575 3755 3891 ptg000031l:403748-448492 P41234 7.56e-31 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Mus musculus (Mouse) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to steroid hormone [GO:0048545]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512] GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0060049; GO:0061135; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 10119 FUN_039816 2856 1260 1575 3755 3891 ptg000031l:403748-448492 P41234 3.92e-24 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Mus musculus (Mouse) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to steroid hormone [GO:0048545]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512] GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0060049; GO:0061135; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 10120 FUN_039816 2856 1260 1575 3755 3891 ptg000031l:403748-448492 P41234 1.98e-21 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Mus musculus (Mouse) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to steroid hormone [GO:0048545]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512] GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0060049; GO:0061135; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 10121 FUN_039816 2856 1260 1575 3755 3891 ptg000031l:403748-448492 P41234 3.33e-21 ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2) Mus musculus (Mouse) cellular sphingolipid homeostasis [GO:0090156]; central nervous system myelin formation [GO:0032289]; ceramide translocation [GO:0099040]; cholesterol homeostasis [GO:0042632]; ganglioside metabolic process [GO:0001573]; glycosphingolipid metabolic process [GO:0006687]; lipid transport [GO:0006869]; locomotory behavior [GO:0007626]; negative regulation of cholesterol efflux [GO:0090370]; negative regulation of intracellular cholesterol transport [GO:0032384]; negative regulation of low-density lipoprotein receptor activity [GO:1905598]; negative regulation of phospholipid biosynthetic process [GO:0071072]; negative regulation of receptor-mediated endocytosis involved in cholesterol transport [GO:1905601]; negative regulation of sphingolipid biosynthetic process [GO:0090155]; negative regulation of steroid metabolic process [GO:0045939]; positive regulation of amyloid precursor protein biosynthetic process [GO:0042986]; positive regulation of amyloid precursor protein catabolic process [GO:1902993]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of low-density lipoprotein particle receptor catabolic process [GO:0032805]; regulation of intracellular cholesterol transport [GO:0032383]; regulation of post-translational protein modification [GO:1901873]; regulation of protein glycosylation [GO:0060049]; regulation of protein localization to cell periphery [GO:1904375]; regulation of protein localization to cell surface [GO:2000008]; regulation of steroid metabolic process [GO:0019218]; response to steroid hormone [GO:0048545]; sphingomyelin metabolic process [GO:0006684]; sphingosine biosynthetic process [GO:0046512] GO:0001573; GO:0005319; GO:0005524; GO:0005764; GO:0005765; GO:0005768; GO:0005815; GO:0005886; GO:0006684; GO:0006687; GO:0006869; GO:0007626; GO:0010008; GO:0016020; GO:0016887; GO:0019218; GO:0031410; GO:0032289; GO:0032383; GO:0032384; GO:0032805; GO:0042626; GO:0042632; GO:0042986; GO:0043231; GO:0045939; GO:0046512; GO:0048545; GO:0060049; GO:0061135; GO:0071072; GO:0090155; GO:0090156; GO:0090370; GO:0099038; GO:0099040; GO:0140359; GO:1901873; GO:1902004; GO:1902993; GO:1904375; GO:1905598; GO:1905601; GO:2000008 10122 FUN_039815 144 260 231 160 323 NA NA NA NA NA NA NA 10123 FUN_039814 2988 3442 1583 1952 2869 NA NA NA NA NA NA NA 10124 FUN_039813 0 37 0 24 38 ptg000031l:376648-378371 O60704 2.1e-61 Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 2) (TPST-2) Homo sapiens (Human) 3'-phosphoadenosine 5'-phosphosulfate metabolic process [GO:0050427]; peptidyl-tyrosine sulfation [GO:0006478] GO:0000139; GO:0005783; GO:0005794; GO:0006478; GO:0008146; GO:0008476; GO:0042803; GO:0050427 10125 FUN_035235 3203 2170 1820 2434 2595 NA NA NA NA NA NA NA 10126 FUN_039811 104 266 228 324 139 NA NA NA NA NA NA NA 10127 FUN_041406 19 79 52 228 0 NA NA NA NA NA NA NA 10128 FUN_022413 761 938 402 562 621 NA NA NA NA NA NA NA 10129 FUN_022412 5249 5008 2189 3565 2964 NA NA NA NA NA NA NA 10130 FUN_022411 933 484 380 492 628 NA NA NA NA NA NA NA 10131 FUN_022410 578 252 284 366 455 NA NA NA NA NA NA NA 10132 FUN_022417 16 5 0 10 0 NA NA NA NA NA NA NA 10133 FUN_022416 21 13 0 10 0 NA NA NA NA NA NA NA 10134 FUN_022415 308 746 294 241 64 NA NA NA NA NA NA NA 10135 FUN_022414 706 887 608 230 148 NA NA NA NA NA NA NA 10136 FUN_035233 175 63 32 148 79 NA NA NA NA NA NA NA 10137 FUN_022419 289 142 81 111 129 NA NA NA NA NA NA NA 10138 FUN_022418 867 633 623 904 765 NA NA NA NA NA NA NA 10139 FUN_035232 880 640 272 492 642 NA NA NA NA NA NA NA 10140 FUN_024717 33 58 21 86 96 ptg000018l:10235370-10237578 F6QEU4 7.99e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 10141 FUN_024714 0 0 0 7 11 NA NA NA NA NA NA NA 10142 FUN_024715 203 61 101 214 88 ptg000018l:10215185-10219492 F6QEU4 2.26e-51 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 10143 FUN_024712 5 10 0 0 0 NA NA NA NA NA NA NA 10144 FUN_024713 59 33 17 44 40 ptg000018l:10198303-10201938 E7FAM5 5.2e-52 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 10145 FUN_024710 0 0 17 0 0 NA NA NA NA NA NA NA 10146 FUN_024711 128 23 46 36 9 ptg000018l:10172882-10175203 F6QEU4 1.95e-52 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 10147 FUN_035230 0 0 0 17 0 NA NA NA NA NA NA NA 10148 FUN_024718 504 507 207 1154 1220 NA NA NA NA NA NA NA 10149 FUN_024719 831 437 520 573 781 NA NA NA NA NA NA NA 10150 FUN_017698 0 0 0 0 25 NA NA NA NA NA NA NA 10151 FUN_001413 2782 1753 1125 4568 2547 NA NA NA NA NA NA NA 10152 FUN_017691 0 0 0 0 29 ptg000011l:13249956-13264106 O00370 1.45e-84 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 10153 FUN_017691 0 0 0 0 29 ptg000011l:13249956-13264106 O00370 1.45e-84 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 10154 FUN_017691 0 0 0 0 29 ptg000011l:13249956-13264106 O00370 1.45e-84 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 10155 FUN_017693 1146 1551 8 1228 927 NA NA NA NA NA NA NA 10156 FUN_035238 11981 11189 7263 11199 11564 NA NA NA NA NA NA NA 10157 FUN_019598 222 38 0 203 125 NA NA NA NA NA NA NA 10158 FUN_019599 23 8 0 12 12 NA NA NA NA NA NA NA 10159 FUN_019595 2 0 0 0 48 NA NA NA NA NA NA NA 10160 FUN_019596 0 0 0 0 85 NA NA NA NA NA NA NA 10161 FUN_019597 28 13 0 16 5 NA NA NA NA NA NA NA 10162 FUN_019590 14 0 63 0 140 NA NA NA NA NA NA NA 10163 FUN_025438 344 354 146 305 223 NA NA NA NA NA NA NA 10164 FUN_044110 4 5 16 3 101 NA NA NA NA NA NA NA 10165 FUN_025439 290 223 221 195 249 NA NA NA NA NA NA NA 10166 FUN_039824 3768 3026 1339 2443 2066 ptg000031l:555513-560649 P42700 2.36e-73 RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0005737; GO:0030030; GO:0034336; GO:0046872; GO:1990904 10167 FUN_039824 3768 3026 1339 2443 2066 ptg000031l:555513-560649 P42700 5.41e-30 RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0005737; GO:0030030; GO:0034336; GO:0046872; GO:1990904 10168 FUN_039824 3768 3026 1339 2443 2066 ptg000031l:555513-560649 P42700 3.92e-28 RNA-binding protein RO60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Xenopus laevis (African clawed frog) cell projection organization [GO:0030030] GO:0005737; GO:0030030; GO:0034336; GO:0046872; GO:1990904 10169 FUN_022429 23503 30088 16340 22686 18023 NA NA NA NA NA NA NA 10170 FUN_035251 2474 2546 943 1329 613 NA NA NA NA NA NA NA 10171 FUN_035253 21 0 11 18 91 ptg000025l:5657043-5671767 Q96DM1 1.97e-38 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 10172 FUN_035252 207 206 109 214 103 NA NA NA NA NA NA NA 10173 FUN_035255 709 655 812 1340 1038 ptg000025l:5683492-5689449 O16025 3.25e-32 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10174 FUN_006388 0 0 22 0 45 NA NA NA NA NA NA NA 10175 FUN_035257 1586 963 839 1745 2214 ptg000025l:5695098-5705726 O16025 7.24e-29 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10176 FUN_035257 1586 963 839 1745 2214 ptg000025l:5695098-5705726 O16025 1.14e-28 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10177 FUN_035256 496 342 291 985 678 ptg000025l:5689970-5691064 O16025 3.4e-36 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10178 FUN_035259 4782 4084 2045 3143 1495 ptg000025l:5730593-5743367 O16025 1.25e-53 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10179 FUN_035258 0 0 15 54 82 ptg000025l:5712789-5728796 O16025 3.5e-28 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 10180 FUN_006387 23 0 13 0 55 NA NA NA NA NA NA NA 10181 FUN_006386 0 0 0 13 25 NA NA NA NA NA NA NA 10182 FUN_006383 7 0 0 0 16 NA NA NA NA NA NA NA 10183 FUN_006382 7 49 0 13 21 NA NA NA NA NA NA NA 10184 FUN_038036 1101 974 907 711 1148 NA NA NA NA NA NA NA 10185 FUN_038037 507 506 291 433 432 ptg000027l:1680559-1682039 Q3B8H3 1.22e-68 Transmembrane protein 11-B, mitochondrial Xenopus laevis (African clawed frog) mitochondrion organization [GO:0007005] GO:0005743; GO:0007005 10186 FUN_038034 1262 693 604 1026 1166 NA NA NA NA NA NA NA 10187 FUN_038032 413 219 228 129 1882 NA NA NA NA NA NA NA 10188 FUN_038033 2343 1533 939 1894 1619 NA NA NA NA NA NA NA 10189 FUN_038030 23 15 44 31 0 NA NA NA NA NA NA NA 10190 FUN_038031 0 7 0 17 0 ptg000027l:1643333-1644743 Q96P65 1.97e-30 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 10191 FUN_009164 12 21 6 12 0 NA NA NA NA NA NA NA 10192 FUN_025432 216 288 308 318 383 NA NA NA NA NA NA NA 10193 FUN_038038 3454 2891 1815 2933 2535 NA NA NA NA NA NA NA 10194 FUN_038039 11 0 18 3 24 NA NA NA NA NA NA NA 10195 FUN_025433 4 6 0 5 11 NA NA NA NA NA NA NA 10196 FUN_022426 7580 7785 6382 6894 6927 NA NA NA NA NA NA NA 10197 FUN_022427 1932 2205 1429 3863 1091 NA NA NA NA NA NA NA 10198 FUN_009168 5 10 33 3 0 NA NA NA NA NA NA NA 10199 FUN_039726 0 0 16 0 9 NA NA NA NA NA NA NA 10200 FUN_025436 425 308 178 384 251 NA NA NA NA NA NA NA 10201 FUN_022724 1717 1000 930 1209 1089 ptg000016l:12677961-12682946 P25291 4.69e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 10202 FUN_022724 1717 1000 930 1209 1089 ptg000016l:12677961-12682946 P25291 4.69e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 10203 FUN_007203 87 408 76 223 650 NA NA NA NA NA NA NA 10204 FUN_025437 234 116 86 305 489 NA NA NA NA NA NA NA 10205 FUN_030555 0 0 0 0 22 ptg000023l:11455982-11461220 P84239 2.66e-82 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10206 FUN_030555 0 0 0 0 22 ptg000023l:11455982-11461220 P84239 2.66e-82 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10207 FUN_030554 0 0 0 0 12 ptg000023l:11451152-11455023 P84239 1.12e-82 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10208 FUN_030556 0 0 0 0 27 NA NA NA NA NA NA NA 10209 FUN_030550 13 0 0 0 5 NA NA NA NA NA NA NA 10210 FUN_030552 244 2 28 11 137 NA NA NA NA NA NA NA 10211 FUN_007200 22 0 0 0 0 NA NA NA NA NA NA NA 10212 FUN_042004 497 367 392 587 378 ptg000035l:9744850-9748309 Q32KI9 1.29e-25 Arylsulfatase I (ASI) (EC 3.1.6.-) Mus musculus (Mouse) NA GO:0005576; GO:0005783; GO:0008484; GO:0046872 10213 FUN_042004 497 367 392 587 378 ptg000035l:9744850-9748309 Q32KI9 1.29e-25 Arylsulfatase I (ASI) (EC 3.1.6.-) Mus musculus (Mouse) NA GO:0005576; GO:0005783; GO:0008484; GO:0046872 10214 FUN_036780 0 0 18 6 32 NA NA NA NA NA NA NA 10215 FUN_007265 0 0 7 0 0 ptg000002l:669822-677079 Q95SX7 9.52e-35 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 10216 FUN_007264 13 1 19 1 24 NA NA NA NA NA NA NA 10217 FUN_044011 24 31 2 34 14 NA NA NA NA NA NA NA 10218 FUN_007266 0 0 4 5 14 ptg000002l:712774-721941 P35067 5.14e-72 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10219 FUN_007268 0 0 0 0 6 NA NA NA NA NA NA NA 10220 FUN_035789 8 0 0 0 29 NA NA NA NA NA NA NA 10221 FUN_035788 31 0 0 7 14 NA NA NA NA NA NA NA 10222 FUN_035781 24 0 0 7 13 NA NA NA NA NA NA NA 10223 FUN_035780 0 15 0 14 283 NA NA NA NA NA NA NA 10224 FUN_035786 7 0 0 0 7 NA NA NA NA NA NA NA 10225 FUN_035784 19 0 36 0 68 NA NA NA NA NA NA NA 10226 FUN_036258 741 305 147 544 531 NA NA NA NA NA NA NA 10227 FUN_036259 305 145 26 74 89 NA NA NA NA NA NA NA 10228 FUN_031208 0 0 0 12 102 NA NA NA NA NA NA NA 10229 FUN_031209 63 76 77 173 103 NA NA NA NA NA NA NA 10230 FUN_031202 5 9 0 2 30 NA NA NA NA NA NA NA 10231 FUN_031203 123 251 93 231 209 ptg000023l:17931395-17948745 Q94K49 1.64e-23 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 10232 FUN_031206 1155 712 533 1047 1147 NA NA NA NA NA NA NA 10233 FUN_031207 123 149 75 225 199 NA NA NA NA NA NA NA 10234 FUN_031204 48 59 0 29 11 NA NA NA NA NA NA NA 10235 FUN_031205 2305 2117 960 1805 1315 NA NA NA NA NA NA NA 10236 FUN_037789 1212 620 596 697 494 NA NA NA NA NA NA NA 10237 FUN_037788 0 12 0 0 22 NA NA NA NA NA NA NA 10238 FUN_037785 33 0 15 0 0 NA NA NA NA NA NA NA 10239 FUN_037784 1085 301 423 780 472 NA NA NA NA NA NA NA 10240 FUN_037787 601 486 353 493 486 NA NA NA NA NA NA NA 10241 FUN_037781 0 0 0 1 13 NA NA NA NA NA NA NA 10242 FUN_037780 0 0 0 0 11 NA NA NA NA NA NA NA 10243 FUN_037783 60 138 103 406 419 NA NA NA NA NA NA NA 10244 FUN_037782 3428 2613 1223 4108 2277 NA NA NA NA NA NA NA 10245 FUN_027436 0 5 22 37 23 NA NA NA NA NA NA NA 10246 FUN_027437 0 24 103 9 35 NA NA NA NA NA NA NA 10247 FUN_027435 221 7151 6196 21 19 ptg000021l:5087053-5089352 Q66KV4 5.07e-23 Barrier-to-autointegration factor B Xenopus laevis (African clawed frog) negative regulation of protein ADP-ribosylation [GO:0010836]; response to oxidative stress [GO:0006979] GO:0000785; GO:0003677; GO:0005635; GO:0005737; GO:0006979; GO:0010836 10248 FUN_027432 3 1 3 1 18 NA NA NA NA NA NA NA 10249 FUN_027430 9 1 18 4 70 NA NA NA NA NA NA NA 10250 FUN_027438 0 0 30 344 0 NA NA NA NA NA NA NA 10251 FUN_027439 0 4 21 0 0 NA NA NA NA NA NA NA 10252 FUN_028558 388 1289 139 539 1164 NA NA NA NA NA NA NA 10253 FUN_033775 2759 1703 1458 3126 2128 ptg000024l:1249228-1260516 Q6E2N3 8.56e-58 E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (Protein moonshine) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33) Danio rerio (Zebrafish) (Brachydanio rerio) developmental pigmentation [GO:0048066]; embryonic hemopoiesis [GO:0035162]; erythrocyte differentiation [GO:0030218]; fin development [GO:0033333]; macrophage chemotaxis [GO:0048246]; macrophage migration [GO:1905517]; neutrophil chemotaxis [GO:0030593]; neutrophil migration [GO:1990266]; post-embryonic hemopoiesis [GO:0035166]; primitive hemopoiesis [GO:0060215]; protein ubiquitination [GO:0016567]; regulation of transcription elongation by RNA polymerase II [GO:0034243] GO:0003677; GO:0005634; GO:0008270; GO:0016567; GO:0016740; GO:0030218; GO:0030593; GO:0033333; GO:0034243; GO:0035162; GO:0035166; GO:0048066; GO:0048246; GO:0060215; GO:1905517; GO:1990266 10254 FUN_037128 0 6 0 14 4 ptg000026l:6130233-6131514 Q7Z494 1.07e-47 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10255 FUN_037128 0 6 0 14 4 ptg000026l:6130233-6131514 Q7Z494 2.5e-38 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10256 FUN_037128 0 6 0 14 4 ptg000026l:6130233-6131514 Q7Z494 1.59e-31 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10257 FUN_037128 0 6 0 14 4 ptg000026l:6130233-6131514 Q7Z494 1.92e-24 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10258 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 1.62e-48 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10259 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 4.45e-48 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10260 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 1.5e-46 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10261 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 4.63e-40 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10262 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 4.24e-39 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10263 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 1.05e-38 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10264 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 1.35e-34 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10265 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 1.35e-34 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10266 FUN_037120 1665 23 62 174 124 ptg000026l:6057519-6061948 Q7TNH6 5.17e-34 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 10267 FUN_037123 299 0 34 3 43 NA NA NA NA NA NA NA 10268 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 1.71e-49 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10269 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 1.1e-46 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10270 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 1.74e-46 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10271 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 1.04e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10272 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 1.99e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10273 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 1.13e-43 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10274 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 5.42e-43 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10275 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 3.2e-40 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10276 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 4.86e-38 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10277 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 3e-34 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10278 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 3.12e-33 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10279 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 3.19e-24 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10280 FUN_037122 567 11 3 95 139 ptg000026l:6076961-6082285 Q7Z494 3.33e-24 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10281 FUN_037125 180 0 0 0 16 NA NA NA NA NA NA NA 10282 FUN_037124 86 109 0 49 356 NA NA NA NA NA NA NA 10283 FUN_037127 0 5 0 6 4 ptg000026l:6128850-6130131 Q7Z494 1.07e-47 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10284 FUN_037127 0 5 0 6 4 ptg000026l:6128850-6130131 Q7Z494 2.5e-38 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10285 FUN_037127 0 5 0 6 4 ptg000026l:6128850-6130131 Q7Z494 1.59e-31 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10286 FUN_037127 0 5 0 6 4 ptg000026l:6128850-6130131 Q7Z494 1.92e-24 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10287 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 1.4e-53 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10288 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 1.96e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10289 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 3.87e-49 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10290 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 2.13e-48 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10291 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 1.6e-46 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10292 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 1.88e-43 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10293 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 2.53e-40 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10294 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 3.56e-40 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10295 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 3.65e-40 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10296 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 1.23e-37 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10297 FUN_037126 349 107 266 336 681 ptg000026l:6123198-6128748 Q7Z494 9.53e-22 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 10298 FUN_006608 635 600 296 303 205 NA NA NA NA NA NA NA 10299 FUN_006609 54 0 1 0 2 NA NA NA NA NA NA NA 10300 FUN_006602 1511 951 739 1412 975 ptg000001l:14605987-14619181 P97819 2.53e-26 85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (2-lysophosphatidylcholine acylhydrolase) (EC 3.1.1.5) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9) Mus musculus (Mouse) antibacterial humoral response [GO:0019731]; cardiolipin acyl-chain remodeling [GO:0035965]; cardiolipin biosynthetic process [GO:0032049]; chemotaxis [GO:0006935]; maternal process involved in female pregnancy [GO:0060135]; memory [GO:0007613]; negative regulation of synaptic transmission, glutamatergic [GO:0051967]; phosphatidic acid metabolic process [GO:0046473]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylethanolamine catabolic process [GO:0046338]; platelet activating factor metabolic process [GO:0046469]; positive regulation of arachidonic acid secretion [GO:0090238]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of exocytosis [GO:0045921]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; regulation of store-operated calcium channel activity [GO:1901339]; response to endoplasmic reticulum stress [GO:0034976]; urinary bladder smooth muscle contraction [GO:0014832]; vasodilation [GO:0042311] GO:0001934; GO:0003847; GO:0004622; GO:0005516; GO:0005615; GO:0005739; GO:0005829; GO:0005886; GO:0006935; GO:0007204; GO:0007613; GO:0014832; GO:0016290; GO:0017171; GO:0019731; GO:0019901; GO:0031143; GO:0032049; GO:0034451; GO:0034638; GO:0034976; GO:0035774; GO:0035965; GO:0042311; GO:0042802; GO:0043008; GO:0045921; GO:0046338; GO:0046469; GO:0046473; GO:0047499; GO:0051967; GO:0060135; GO:0090037; GO:0090200; GO:0090238; GO:0102545; GO:0102991; GO:1901339; GO:2000304 10301 FUN_006603 441 490 206 534 191 NA NA NA NA NA NA NA 10302 FUN_006604 116 17 11 106 61 NA NA NA NA NA NA NA 10303 FUN_006605 246 710 155 357 565 NA NA NA NA NA NA NA 10304 FUN_006606 294 85 181 0 241 NA NA NA NA NA NA NA 10305 FUN_006607 1700 13 1058 362 577 NA NA NA NA NA NA NA 10306 FUN_032571 7949 562 1672 768 1807 ptg000023l:33316696-33318379 O95497 6.71e-138 Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Tiff66) (Vascular non-inflammatory molecule 1) (Vanin-1) Homo sapiens (Human) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089]; response to oxidative stress [GO:0006979] GO:0002526; GO:0002544; GO:0005576; GO:0005886; GO:0006954; GO:0006979; GO:0015939; GO:0016020; GO:0017159; GO:0033089; GO:0035577; GO:0045087; GO:0098609; GO:1902177 10307 FUN_032570 176 115 16 199 31 ptg000023l:33311722-33314371 Q5M7N9 3.87e-84 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 10308 FUN_032573 1062 286 582 476 152 ptg000023l:33325665-33330370 Q90876 2.29e-24 Interferon regulatory factor 1 (IRF-1) Gallus gallus (Chicken) immune system process [GO:0002376]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0002376; GO:0005634; GO:0005737; GO:0006357 10309 FUN_032572 200 46 175 86 115 NA NA NA NA NA NA NA 10310 FUN_032575 860 787 494 988 479 NA NA NA NA NA NA NA 10311 FUN_032574 9675 7998 4190 5594 3508 ptg000023l:33332586-33338586 Q8R4E0 3.51e-38 Interferon regulatory factor 2 (IRF-2) Sigmodon hispidus (Hispid cotton rat) NA GO:0000976; GO:0003700; GO:0005634 10312 FUN_032577 26 0 0 0 0 NA NA NA NA NA NA NA 10313 FUN_032576 25 0 34 16 12 NA NA NA NA NA NA NA 10314 FUN_032579 1064 916 806 1713 549 ptg000023l:33387681-33388017 B8UU74 3.43e-23 Uncharacterized skeletal organic matrix protein 4 (Uncharacterized SOMP-4) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 10315 FUN_032578 327 0 206 0 3 NA NA NA NA NA NA NA 10316 FUN_025601 94 40 21 48 42 NA NA NA NA NA NA NA 10317 FUN_003541 0 0 0 0 11 NA NA NA NA NA NA NA 10318 FUN_003542 0 28 1 0 21 NA NA NA NA NA NA NA 10319 FUN_003543 0 0 0 0 6 NA NA NA NA NA NA NA 10320 FUN_003544 0 0 0 0 9 NA NA NA NA NA NA NA 10321 FUN_003545 0 0 20 0 105 NA NA NA NA NA NA NA 10322 FUN_003547 0 0 5 4 13 NA NA NA NA NA NA NA 10323 FUN_003548 0 0 0 0 18 NA NA NA NA NA NA NA 10324 FUN_003549 33 0 51 22 67 NA NA NA NA NA NA NA 10325 FUN_028559 42 62 112 49 200 ptg000022l:697877-702270 Q9Y6A2 7.92e-33 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 10326 FUN_041849 81 29 24 10 30 NA NA NA NA NA NA NA 10327 FUN_041848 71651 73777 43638 29472 19178 ptg000035l:8218375-8219498 P34743 2.15e-22 Protein BTG1 (B-cell translocation gene 1 protein) Gallus gallus (Chicken) negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271] GO:0005634; GO:0005737; GO:0008285; GO:0019899; GO:0045603; GO:0045766; GO:0045930; GO:2000271 10328 FUN_041843 716 269 235 752 708 NA NA NA NA NA NA NA 10329 FUN_041842 2152 2000 1213 1373 1451 NA NA NA NA NA NA NA 10330 FUN_041841 1400 586 603 1008 574 NA NA NA NA NA NA NA 10331 FUN_041840 4596 3717 1675 1694 1871 ptg000035l:8178167-8181241 Q4R6I5 1.24e-43 Clathrin heavy chain linker domain-containing protein 1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 10332 FUN_041847 9 19 20 36 11 NA NA NA NA NA NA NA 10333 FUN_041846 3910 5175 2882 3145 2080 NA NA NA NA NA NA NA 10334 FUN_041845 19 0 7 75 53 ptg000035l:8207783-8209010 Q93126 8.44e-49 Probable G-protein coupled receptor No9 Amphibalanus amphitrite (Striped barnacle) (Balanus amphitrite) NA GO:0004935; GO:0005886 10335 FUN_041844 17 2 0 37 47 ptg000035l:8205896-8206892 P18130 4.84e-51 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 10336 FUN_001379 5 0 3 19 56 NA NA NA NA NA NA NA 10337 FUN_001378 570 281 119 897 618 NA NA NA NA NA NA NA 10338 FUN_001371 879 774 345 598 557 ntLink_6:11619732-11622074 P30975 2.45e-21 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 10339 FUN_001370 170 84 200 402 254 NA NA NA NA NA NA NA 10340 FUN_001373 17 58 7 105 39 NA NA NA NA NA NA NA 10341 FUN_001372 78 29 29 36 20 ntLink_6:11623979-11628068 Q924H0 3.23e-33 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 10342 FUN_001375 17 1 6 12 30 NA NA NA NA NA NA NA 10343 FUN_001374 0 0 0 0 9 NA NA NA NA NA NA NA 10344 FUN_001377 724 897 330 1437 985 NA NA NA NA NA NA NA 10345 FUN_001376 311 517 87 336 198 ntLink_6:11706205-11708939 P05363 1.04e-34 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Bos taurus (Bovine) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0016497; GO:0061827; GO:0070472; GO:0097225; GO:1902093 10346 FUN_035305 399 172 52 235 479 NA NA NA NA NA NA NA 10347 FUN_002630 0 0 18 124 25 NA NA NA NA NA NA NA 10348 FUN_002633 618 107 161 184 66 NA NA NA NA NA NA NA 10349 FUN_002632 181 2 37 27 19 NA NA NA NA NA NA NA 10350 FUN_002637 17 0 20 22 0 NA NA NA NA NA NA NA 10351 FUN_002636 1364 0 314 0 6 NA NA NA NA NA NA NA 10352 FUN_002639 301 2042 305 182 207 NA NA NA NA NA NA NA 10353 FUN_011121 0 0 16 7 0 NA NA NA NA NA NA NA 10354 FUN_011120 0 0 0 0 14 NA NA NA NA NA NA NA 10355 FUN_011122 148 0 88 0 12 NA NA NA NA NA NA NA 10356 FUN_035304 253 112 69 131 32 ptg000025l:6214312-6214999 A0A3M6TIF0 3.04e-98 NA NA NA NA 10357 FUN_042989 790 1015 340 455 451 NA NA NA NA NA NA NA 10358 FUN_004150 866 1730 246 73 120 NA NA NA NA NA NA NA 10359 FUN_011697 906 755 506 947 670 NA NA NA NA NA NA NA 10360 FUN_011696 2038 939 838 1343 1330 ptg000008l:282908-303035 Q95SX7 1.71e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 10361 FUN_011695 3623 3151 2075 3452 2612 ptg000008l:267054-281620 Q6EE31 1.3e-21 T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0005524; GO:0005815; GO:0005832; GO:0006457; GO:0016887; GO:0042995; GO:0051082; GO:0140662 10362 FUN_011694 520 463 357 634 440 ptg000008l:261191-264828 Q9UBI9 5.37e-53 Headcase protein homolog (hHDC) Homo sapiens (Human) negative regulation of mitotic cell cycle [GO:0045930]; respiratory tube development [GO:0030323] GO:0005634; GO:0005737; GO:0016020; GO:0030323; GO:0045930 10363 FUN_011694 520 463 357 634 440 ptg000008l:261191-264828 Q9UBI9 2.94e-22 Headcase protein homolog (hHDC) Homo sapiens (Human) negative regulation of mitotic cell cycle [GO:0045930]; respiratory tube development [GO:0030323] GO:0005634; GO:0005737; GO:0016020; GO:0030323; GO:0045930 10364 FUN_011693 8580 7559 4667 5675 4248 ptg000008l:247178-259683 Q96A49 3.83e-24 Synapse-associated protein 1 (BSD domain-containing signal transducer and Akt interactor protein) (BSTA) Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to insulin stimulus [GO:0032869]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; TORC2 signaling [GO:0038203] GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0030154; GO:0030424; GO:0030425; GO:0030426; GO:0031234; GO:0032869; GO:0036120; GO:0038203; GO:0042734; GO:0043204; GO:0045202; GO:0045211; GO:0045600; GO:0048172; GO:0048471; GO:0070062; GO:0071364; GO:0071902; GO:1990314 10365 FUN_011692 5 22 23 13 24 NA NA NA NA NA NA NA 10366 FUN_011691 835 299 212 559 469 ptg000008l:228685-242964 P29145 1.23e-31 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10367 FUN_011691 835 299 212 559 469 ptg000008l:228685-242964 P29145 2.14e-25 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10368 FUN_011691 835 299 212 559 469 ptg000008l:228685-242964 P29145 1.71e-24 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10369 FUN_011691 835 299 212 559 469 ptg000008l:228685-242964 P29145 2.96e-21 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10370 FUN_011690 87 128 25 116 159 ptg000008l:216877-226098 P29145 8.52e-33 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10371 FUN_011690 87 128 25 116 159 ptg000008l:216877-226098 P29145 2.59e-32 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10372 FUN_011690 87 128 25 116 159 ptg000008l:216877-226098 P29145 4.96e-22 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 10373 FUN_011698 2939 1829 1622 1858 1339 ptg000008l:319225-320404 P56222 2.21e-91 POU domain, class 3, transcription factor 2 (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2) (Nervous system-specific octamer-binding transcription factor N-Oct-3) (Octamer-binding protein 7) (Oct-7) (Octamer-binding transcription factor 7) (OTF-7) Rattus norvegicus (Rat) astrocyte development [GO:0014002]; cellular response to organic substance [GO:0071310]; cerebral cortex radially oriented cell migration [GO:0021799]; epidermis development [GO:0008544]; forebrain astrocyte development [GO:0021897]; forebrain ventricular zone progenitor cell division [GO:0021869]; hypothalamus cell differentiation [GO:0021979]; myelination in peripheral nervous system [GO:0022011]; negative regulation of gene expression [GO:0010629]; nervous system development [GO:0007399]; neuroendocrine cell differentiation [GO:0061101]; neurohypophysis development [GO:0021985]; neuron development [GO:0048666]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; neuron fate specification [GO:0048665]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of axonogenesis [GO:0050770]; regulation of cell differentiation [GO:0045595]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044] GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0006357; GO:0007399; GO:0008284; GO:0008544; GO:0010629; GO:0014002; GO:0014044; GO:0021799; GO:0021869; GO:0021897; GO:0021979; GO:0021985; GO:0022011; GO:0030182; GO:0040018; GO:0042802; GO:0043565; GO:0045595; GO:0045944; GO:0048663; GO:0048665; GO:0048666; GO:0050770; GO:0061101; GO:0071310; GO:0071837; GO:1990837 10374 FUN_014316 77 40 19 121 43 NA NA NA NA NA NA NA 10375 FUN_012762 361 163 116 201 196 NA NA NA NA NA NA NA 10376 FUN_012763 45 20 97 64 125 NA NA NA NA NA NA NA 10377 FUN_012761 2 3 39 3 101 NA NA NA NA NA NA NA 10378 FUN_012767 15152 10806 5609 18205 11773 NA NA NA NA NA NA NA 10379 FUN_012764 281 81 87 152 246 NA NA NA NA NA NA NA 10380 FUN_029445 734 426 203 408 426 NA NA NA NA NA NA NA 10381 FUN_029444 537 181 202 168 260 NA NA NA NA NA NA NA 10382 FUN_029447 505 176 137 402 838 NA NA NA NA NA NA NA 10383 FUN_029446 142 7 10 7 214 NA NA NA NA NA NA NA 10384 FUN_029441 1725 938 1991 1410 1544 NA NA NA NA NA NA NA 10385 FUN_029440 223 141 222 221 188 NA NA NA NA NA NA NA 10386 FUN_029443 0 33 0 0 0 NA NA NA NA NA NA NA 10387 FUN_029442 2914 3621 1332 2506 1583 NA NA NA NA NA NA NA 10388 FUN_016472 2466 947 1175 1860 1576 NA NA NA NA NA NA NA 10389 FUN_016473 29 26 44 129 76 ptg000011l:3530889-3536250 A7MB54 7.82e-23 H2.0-like homeobox protein (Homeobox protein HLX1) Bos taurus (Bovine) embryonic digestive tract morphogenesis [GO:0048557]; enteric nervous system development [GO:0048484]; epithelial cell proliferation [GO:0050673]; liver development [GO:0001889]; negative regulation of T-helper 2 cell differentiation [GO:0045629]; organ growth [GO:0035265]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of organ growth [GO:0046622]; positive regulation of T-helper 1 cell differentiation [GO:0045627]; skeletal muscle tissue development [GO:0007519]; T-helper 1 cell differentiation [GO:0045063]; T-helper 2 cell differentiation [GO:0045064] GO:0000981; GO:0001889; GO:0005634; GO:0007519; GO:0035265; GO:0043565; GO:0045063; GO:0045064; GO:0045627; GO:0045629; GO:0046622; GO:0048484; GO:0048557; GO:0050673; GO:0050679 10390 FUN_016470 347 233 124 112 202 NA NA NA NA NA NA NA 10391 FUN_016471 1381 548 412 670 612 NA NA NA NA NA NA NA 10392 FUN_016476 3343 2045 1377 3930 2933 NA NA NA NA NA NA NA 10393 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 9.66e-86 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10394 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 4.94e-58 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10395 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 6.49e-35 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10396 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 3.92e-27 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10397 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 7.97e-27 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10398 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 3.84e-26 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10399 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 5.41e-26 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10400 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 7.63e-26 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10401 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 2.19e-25 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10402 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 2.52e-24 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10403 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 4.26e-24 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10404 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 6.3e-23 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10405 FUN_016474 3589 1750 2074 4553 3092 ptg000011l:3538512-3598044 Q63170 7.14e-23 Dynein axonemal heavy chain 7 (Axonemal beta dynein heavy chain 7) (Axonemal dynein heavy chain b) (Ciliary dynein heavy chain 7) (Dynein-like protein 7) Rattus norvegicus (Rat) cilium movement [GO:0003341]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005509; GO:0005524; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0036159; GO:0045505; GO:0051959 10406 FUN_016475 1925 600 957 1178 1480 ptg000011l:3599779-3626302 Q920R0 4.85e-27 Alsin (Amyotrophic lateral sclerosis 2 protein homolog) Mus musculus (Mouse) axonogenesis [GO:0007409]; behavioral fear response [GO:0001662]; cell death [GO:0008219]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; in utero embryonic development [GO:0001701]; locomotory behavior [GO:0007626]; lysosomal transport [GO:0007041]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; positive regulation of GTPase activity [GO:0043547]; positive regulation of protein kinase activity [GO:0045860]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; Rac protein signal transduction [GO:0016601]; receptor recycling [GO:0001881]; regulation of endosome size [GO:0051036]; regulation of GTPase activity [GO:0043087]; response to oxidative stress [GO:0006979]; synaptic transmission, glutamatergic [GO:0035249]; vesicle organization [GO:0016050] GO:0001662; GO:0001701; GO:0001726; GO:0001881; GO:0005085; GO:0005096; GO:0005634; GO:0005737; GO:0005769; GO:0005813; GO:0005829; GO:0006979; GO:0007032; GO:0007041; GO:0007409; GO:0007528; GO:0007626; GO:0008104; GO:0008219; GO:0014069; GO:0016020; GO:0016050; GO:0016197; GO:0016601; GO:0030027; GO:0030424; GO:0030425; GO:0030426; GO:0031267; GO:0031982; GO:0032991; GO:0035249; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043087; GO:0043197; GO:0043231; GO:0043539; GO:0043547; GO:0045860; GO:0048812; GO:0051036; GO:0051260 10407 FUN_025726 4433 2627 2293 4591 2553 NA NA NA NA NA NA NA 10408 FUN_043553 2951 1340 1283 1988 1736 NA NA NA NA NA NA NA 10409 FUN_043552 69 11 9 105 34 NA NA NA NA NA NA NA 10410 FUN_043551 620 1404 919 1298 1078 NA NA NA NA NA NA NA 10411 FUN_043550 3998 1775 1312 2836 2162 NA NA NA NA NA NA NA 10412 FUN_043557 15 34 0 34 44 NA NA NA NA NA NA NA 10413 FUN_043556 1287 485 275 605 1205 NA NA NA NA NA NA NA 10414 FUN_043555 11372 9788 4384 4017 3974 NA NA NA NA NA NA NA 10415 FUN_043554 59 22 22 14 21 NA NA NA NA NA NA NA 10416 FUN_043559 1305 715 611 847 1051 NA NA NA NA NA NA NA 10417 FUN_043558 1303 1495 802 1639 2127 NA NA NA NA NA NA NA 10418 FUN_015704 313 216 10 298 54 NA NA NA NA NA NA NA 10419 FUN_043700 9 0 0 0 0 NA NA NA NA NA NA NA 10420 FUN_043701 12 2 51 0 197 NA NA NA NA NA NA NA 10421 FUN_006232 18 12 3 0 66 NA NA NA NA NA NA NA 10422 FUN_043707 11 0 0 0 0 NA NA NA NA NA NA NA 10423 FUN_043704 0 0 0 21 479 NA NA NA NA NA NA NA 10424 FUN_022623 1285 1826 1093 1501 2169 NA NA NA NA NA NA NA 10425 FUN_023120 1402 329 322 1007 781 NA NA NA NA NA NA NA 10426 FUN_023122 521 552 343 368 317 ptg000017l:3896337-3901426 Q9VY86 7.03e-29 TM2 domain-containing protein CG11103 Drosophila melanogaster (Fruit fly) positive regulation of Notch signaling pathway [GO:0045747] GO:0005886; GO:0045747 10427 FUN_028716 0 0 0 0 61 NA NA NA NA NA NA NA 10428 FUN_028717 20 5 0 5 0 NA NA NA NA NA NA NA 10429 FUN_023127 170 23 90 205 218 NA NA NA NA NA NA NA 10430 FUN_023128 6 0 0 1 1 NA NA NA NA NA NA NA 10431 FUN_023129 833 411 546 488 469 NA NA NA NA NA NA NA 10432 FUN_012322 0 0 0 6 62 NA NA NA NA NA NA NA 10433 FUN_012320 24 0 19 30 33 NA NA NA NA NA NA NA 10434 FUN_012321 43 0 71 173 116 NA NA NA NA NA NA NA 10435 FUN_012326 160 102 149 267 202 NA NA NA NA NA NA NA 10436 FUN_012327 820 644 446 1360 963 NA NA NA NA NA NA NA 10437 FUN_041023 21 7 11 0 89 NA NA NA NA NA NA NA 10438 FUN_012325 1665 1343 1236 1071 567 NA NA NA NA NA NA NA 10439 FUN_009362 113 71 0 0 95 NA NA NA NA NA NA NA 10440 FUN_009363 1453 798 823 1149 1676 NA NA NA NA NA NA NA 10441 FUN_009360 218 0 0 249 191 NA NA NA NA NA NA NA 10442 FUN_009361 669 636 113 2715 931 NA NA NA NA NA NA NA 10443 FUN_002198 0 0 2 1 48 NA NA NA NA NA NA NA 10444 FUN_009364 0 0 45 0 89 NA NA NA NA NA NA NA 10445 FUN_009365 5 0 22 0 260 NA NA NA NA NA NA NA 10446 FUN_002194 1644 18 1953 20 2171 NA NA NA NA NA NA NA 10447 FUN_002195 502 806 506 654 333 NA NA NA NA NA NA NA 10448 FUN_002196 0 0 0 0 8 NA NA NA NA NA NA NA 10449 FUN_009369 1819 634 961 1185 1155 NA NA NA NA NA NA NA 10450 FUN_002192 949 5 1021 5 518 NA NA NA NA NA NA NA 10451 FUN_002193 8 0 24 0 146 NA NA NA NA NA NA NA 10452 FUN_035224 491 495 335 599 507 NA NA NA NA NA NA NA 10453 FUN_011909 2095 1595 1318 2553 1668 NA NA NA NA NA NA NA 10454 FUN_011908 3672 2481 2135 3135 2176 ptg000008l:2748000-2770398 Q5R4G2 4.12e-31 Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid catabolic process [GO:0016042]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283] GO:0001650; GO:0003847; GO:0005829; GO:0005886; GO:0007283; GO:0008247; GO:0016042; GO:0016239; GO:0042803; GO:0046982 10455 FUN_011907 189 114 112 294 270 NA NA NA NA NA NA NA 10456 FUN_011906 2293 1923 1709 2900 2407 NA NA NA NA NA NA NA 10457 FUN_011905 275 487 77 378 596 NA NA NA NA NA NA NA 10458 FUN_011904 446 345 169 349 314 ptg000008l:2719327-2720677 Q8K2J9 2.52e-76 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 10459 FUN_011903 141 380 87 134 134 NA NA NA NA NA NA NA 10460 FUN_011902 1727 1250 892 1381 1580 ptg000008l:2672984-2690812 Q5JWR5 2.82e-54 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 10461 FUN_011902 1727 1250 892 1381 1580 ptg000008l:2672984-2690812 Q5JWR5 5.13e-40 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 10462 FUN_011902 1727 1250 892 1381 1580 ptg000008l:2672984-2690812 Q5JWR5 2.76e-36 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 10463 FUN_011902 1727 1250 892 1381 1580 ptg000008l:2672984-2690812 Q5JWR5 4.27e-30 Protein dopey-1 Homo sapiens (Human) Golgi to endosome transport [GO:0006895]; protein transport [GO:0015031] GO:0000139; GO:0005768; GO:0005802; GO:0005829; GO:0006895; GO:0015031 10464 FUN_011901 745 419 338 374 376 NA NA NA NA NA NA NA 10465 FUN_011900 433 534 206 719 198 ptg000008l:2660787-2661702 Q9GRC0 2.85e-78 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 10466 FUN_041794 176 164 82 421 246 NA NA NA NA NA NA NA 10467 FUN_035225 267 32 98 116 217 ptg000025l:5341150-5341645 Q8BFQ2 5.6e-35 Transmembrane protein 229B Mus musculus (Mouse) macrophage activation [GO:0042116]; response to bacterium [GO:0009617] GO:0009617; GO:0016020; GO:0042116 10468 FUN_016179 0 398 223 2075 887 NA NA NA NA NA NA NA 10469 FUN_016178 0 0 14 0 0 NA NA NA NA NA NA NA 10470 FUN_025607 33 50 25 27 228 ptg000019l:4898958-4905553 Q07496 2.65e-22 Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (cEK8) Gallus gallus (Chicken) axon guidance [GO:0007411]; cell adhesion [GO:0007155]; fasciculation of sensory neuron axon [GO:0097155]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of kinase activity [GO:0033674]; positive regulation of Rho guanyl-nucleotide exchange factor activity [GO:2001108]; protein autophosphorylation [GO:0046777]; regulation of GTPase activity [GO:0043087]; segmentation [GO:0035282]; somitogenesis [GO:0001756]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001756; GO:0004672; GO:0004714; GO:0005004; GO:0005005; GO:0005524; GO:0005737; GO:0005886; GO:0007155; GO:0007169; GO:0007411; GO:0018108; GO:0031901; GO:0033674; GO:0035282; GO:0043005; GO:0043087; GO:0043197; GO:0043235; GO:0046777; GO:0097155; GO:0097161; GO:2001108 10471 FUN_022650 0 0 0 0 31 ptg000016l:11941026-11941878 Q6NS09 1.21e-27 Transmembrane protein 45B Xenopus laevis (African clawed frog) NA GO:0016020 10472 FUN_025605 406 17 455 443 97 NA NA NA NA NA NA NA 10473 FUN_025604 661 401 258 476 532 NA NA NA NA NA NA NA 10474 FUN_025603 198 64 79 104 157 NA NA NA NA NA NA NA 10475 FUN_022654 259 69 330 208 120 ptg000016l:12009928-12015949 P36514 1.06e-22 UDP-glucuronosyltransferase 2C1 (UDPGT 2C1) (EC 2.4.1.17) Oryctolagus cuniculus (Rabbit) lipid metabolic process [GO:0006629] GO:0005789; GO:0006629; GO:0015020 10476 FUN_022657 0 9 9 16 11 NA NA NA NA NA NA NA 10477 FUN_025600 608 363 324 474 573 ptg000019l:4860092-4870604 Q8VE18 7.32e-26 Nonsense-mediated mRNA decay factor SMG8 (Protein smg-8 homolog) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; regulation of protein kinase activity [GO:0045859] GO:0000184; GO:0045859 10478 FUN_022659 567 367 174 273 444 NA NA NA NA NA NA NA 10479 FUN_022658 59 35 46 0 19 NA NA NA NA NA NA NA 10480 FUN_013820 6 0 0 0 0 NA NA NA NA NA NA NA 10481 FUN_025609 121 13 216 94 77 NA NA NA NA NA NA NA 10482 FUN_025608 145 0 397 341 16 NA NA NA NA NA NA NA 10483 FUN_008105 11 9 3 6 10 NA NA NA NA NA NA NA 10484 FUN_008104 122553 115377 58998 131286 85314 ptg000002l:8078693-8083516 O03986 8.1e-165 Heat shock protein 90-4 (AtHSP90.4) (AtHsp90-4) (Heat shock protein 81-4) (Hsp81-4) Arabidopsis thaliana (Mouse-ear cress) cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0000325; GO:0003729; GO:0005524; GO:0005794; GO:0005829; GO:0005886; GO:0006457; GO:0009505; GO:0009536; GO:0009570; GO:0016887; GO:0032991; GO:0034605; GO:0048046; GO:0048471; GO:0050821; GO:0051082; GO:0140662 10485 FUN_008104 122553 115377 58998 131286 85314 ptg000002l:8078693-8083516 O03986 8.1e-165 Heat shock protein 90-4 (AtHSP90.4) (AtHsp90-4) (Heat shock protein 81-4) (Hsp81-4) Arabidopsis thaliana (Mouse-ear cress) cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0000325; GO:0003729; GO:0005524; GO:0005794; GO:0005829; GO:0005886; GO:0006457; GO:0009505; GO:0009536; GO:0009570; GO:0016887; GO:0032991; GO:0034605; GO:0048046; GO:0048471; GO:0050821; GO:0051082; GO:0140662 10486 FUN_008104 122553 115377 58998 131286 85314 ptg000002l:8078693-8083516 O03986 6.6e-40 Heat shock protein 90-4 (AtHSP90.4) (AtHsp90-4) (Heat shock protein 81-4) (Hsp81-4) Arabidopsis thaliana (Mouse-ear cress) cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0000325; GO:0003729; GO:0005524; GO:0005794; GO:0005829; GO:0005886; GO:0006457; GO:0009505; GO:0009536; GO:0009570; GO:0016887; GO:0032991; GO:0034605; GO:0048046; GO:0048471; GO:0050821; GO:0051082; GO:0140662 10487 FUN_008104 122553 115377 58998 131286 85314 ptg000002l:8078693-8083516 O03986 1.79e-21 Heat shock protein 90-4 (AtHSP90.4) (AtHsp90-4) (Heat shock protein 81-4) (Hsp81-4) Arabidopsis thaliana (Mouse-ear cress) cellular response to heat [GO:0034605]; protein folding [GO:0006457]; protein stabilization [GO:0050821] GO:0000325; GO:0003729; GO:0005524; GO:0005794; GO:0005829; GO:0005886; GO:0006457; GO:0009505; GO:0009536; GO:0009570; GO:0016887; GO:0032991; GO:0034605; GO:0048046; GO:0048471; GO:0050821; GO:0051082; GO:0140662 10488 FUN_024556 3915 4882 3815 4034 4009 ptg000018l:8278934-8289276 Q96IV6 1.54e-34 Fatty acid hydroxylase domain-containing protein 2 Homo sapiens (Human) positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of protein phosphorylation [GO:0001934]; sterol biosynthetic process [GO:0016126] GO:0000254; GO:0001934; GO:0005506; GO:0005737; GO:0005789; GO:0016020; GO:0016126; GO:0016491; GO:0045654 10489 FUN_008106 217 182 150 147 134 NA NA NA NA NA NA NA 10490 FUN_008101 2386 1389 1097 1896 2171 ptg000002l:8025039-8035326 Q13573 1.52e-24 SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) Homo sapiens (Human) cellular response to retinoic acid [GO:0071300]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vitamin D receptor signaling pathway [GO:0070564]; regulation of retinoic acid receptor signaling pathway [GO:0048385]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of vitamin D receptor signaling pathway [GO:0070562]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000122; GO:0000398; GO:0003713; GO:0003714; GO:0003723; GO:0005112; GO:0005634; GO:0005654; GO:0005681; GO:0006357; GO:0016363; GO:0016604; GO:0016607; GO:0016922; GO:0019899; GO:0030511; GO:0042771; GO:0042809; GO:0042974; GO:0043923; GO:0045892; GO:0045944; GO:0046332; GO:0048026; GO:0048384; GO:0048385; GO:0050681; GO:0050769; GO:0051571; GO:0070562; GO:0070564; GO:0071007; GO:0071013; GO:0071300 10491 FUN_008100 1524 664 542 514 548 NA NA NA NA NA NA NA 10492 FUN_008103 1726 3410 1555 6642 3119 NA NA NA NA NA NA NA 10493 FUN_024553 7 0 12 0 66 NA NA NA NA NA NA NA 10494 FUN_008109 571 924 859 463 261 NA NA NA NA NA NA NA 10495 FUN_024559 4421 3342 2669 3648 3232 ptg000018l:8324432-8327998 Q56I99 2.94e-118 Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (SMAD family member 5) (SMAD 5) (Smad5) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0030509; GO:0046872; GO:0060395; GO:0070411; GO:0071144 10496 FUN_024559 4421 3342 2669 3648 3232 ptg000018l:8324432-8327998 Q56I99 1.39e-57 Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (SMAD family member 5) (SMAD 5) (Smad5) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0030509; GO:0046872; GO:0060395; GO:0070411; GO:0071144 10497 FUN_042252 12 0 22 4 125 NA NA NA NA NA NA NA 10498 FUN_022629 12292 6394 7200 13970 11618 ptg000016l:11573658-11620956 Q8NEZ4 2.4e-26 Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3) Homo sapiens (Human) chromatin organization [GO:0006325]; histone H3-K4 methylation [GO:0051568]; histone H3-K4 monomethylation [GO:0097692]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003677; GO:0003713; GO:0003723; GO:0005634; GO:0005654; GO:0006325; GO:0016746; GO:0035097; GO:0042054; GO:0042393; GO:0042800; GO:0044666; GO:0045944; GO:0046872; GO:0051568; GO:0097692; GO:0140945 10499 FUN_016171 69 156 147 153 401 NA NA NA NA NA NA NA 10500 FUN_016170 11 0 0 5 2 NA NA NA NA NA NA NA 10501 FUN_010058 0 0 0 0 18 NA NA NA NA NA NA NA 10502 FUN_010052 29 16 0 0 38 NA NA NA NA NA NA NA 10503 FUN_010053 0 0 22 0 10 NA NA NA NA NA NA NA 10504 FUN_022380 474 488 271 514 324 NA NA NA NA NA NA NA 10505 FUN_022387 77 35 84 32 11 NA NA NA NA NA NA NA 10506 FUN_022385 241 145 152 273 97 ptg000016l:8408288-8412740 P00765 4.7e-28 Trypsin-1 (EC 3.4.21.4) (Trypsin I) Astacus astacus (Noble crayfish) (Astacus fluviatilis) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872 10507 FUN_022384 10 73 29 11 70 NA NA NA NA NA NA NA 10508 FUN_010782 592 169 52 286 132 NA NA NA NA NA NA NA 10509 FUN_028212 21 21 8 0 43 NA NA NA NA NA NA NA 10510 FUN_028211 2358 2029 507 224 1537 NA NA NA NA NA NA NA 10511 FUN_028210 21 73 0 37 48 NA NA NA NA NA NA NA 10512 FUN_010786 4183 2181 1588 7854 4928 NA NA NA NA NA NA NA 10513 FUN_028215 49 20 3 0 11 NA NA NA NA NA NA NA 10514 FUN_028214 677 2225 393 958 2031 NA NA NA NA NA NA NA 10515 FUN_028219 0 29 0 34 75 NA NA NA NA NA NA NA 10516 FUN_019866 0 0 7 0 35 NA NA NA NA NA NA NA 10517 FUN_028218 0 0 0 0 22 NA NA NA NA NA NA NA 10518 FUN_019861 0 0 6 4 0 NA NA NA NA NA NA NA 10519 FUN_015109 49822 31472 32862 68071 67007 ptg000009l:6277209-6391926 D3ZHV2 1.6e-34 Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7) Rattus norvegicus (Rat) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006620; GO:0007163; GO:0008017; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 10520 FUN_015109 49822 31472 32862 68071 67007 ptg000009l:6277209-6391926 D3ZHV2 6.7e-23 Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7) Rattus norvegicus (Rat) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006620; GO:0007163; GO:0008017; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 10521 FUN_015109 49822 31472 32862 68071 67007 ptg000009l:6277209-6391926 D3ZHV2 3.96e-21 Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7) Rattus norvegicus (Rat) establishment or maintenance of cell polarity [GO:0007163]; Golgi to plasma membrane protein transport [GO:0043001]; intermediate filament cytoskeleton organization [GO:0045104]; mesoderm formation [GO:0001707]; positive regulation of axon extension [GO:0045773]; positive regulation of Wnt signaling pathway [GO:0030177]; post-translational protein targeting to endoplasmic reticulum membrane [GO:0006620]; regulation of cell migration [GO:0030334]; regulation of epithelial cell migration [GO:0010632]; regulation of focal adhesion assembly [GO:0051893]; regulation of microtubule-based process [GO:0032886]; regulation of neuron projection arborization [GO:0150011]; Wnt signaling pathway [GO:0016055]; wound healing [GO:0042060] GO:0001707; GO:0003779; GO:0005198; GO:0005509; GO:0005737; GO:0005794; GO:0005874; GO:0005886; GO:0006620; GO:0007163; GO:0008017; GO:0010632; GO:0014069; GO:0015629; GO:0015630; GO:0016020; GO:0016055; GO:0016887; GO:0030177; GO:0030334; GO:0032587; GO:0032886; GO:0042060; GO:0043001; GO:0045104; GO:0045773; GO:0051011; GO:0051015; GO:0051893; GO:0150011 10522 FUN_015108 1156 534 473 893 803 NA NA NA NA NA NA NA 10523 FUN_015103 1404 1065 734 1906 1742 ptg000009l:6182235-6183691 Q9CWK3 1.25e-51 CD2 antigen cytoplasmic tail-binding protein 2 (CD2 cytoplasmic domain-binding protein 2) (CD2 tail-binding protein 2) Mus musculus (Mouse) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0001650; GO:0005634; GO:0005654; GO:0005682; GO:0005829; GO:0006397; GO:0008380; GO:0016607; GO:0043021 10524 FUN_015101 3488 1725 1295 2827 1973 NA NA NA NA NA NA NA 10525 FUN_015100 7471 7290 2452 5063 3286 ptg000009l:6124223-6129444 Q6GR25 2.58e-22 Protein phosphatase PTC7 homolog (EC 3.1.3.16) Xenopus laevis (African clawed frog) NA GO:0005759; GO:0017018; GO:0046872 10526 FUN_015107 3300 1940 1389 2231 944 NA NA NA NA NA NA NA 10527 FUN_015106 53 0 31 9 106 NA NA NA NA NA NA NA 10528 FUN_015105 32 14 19 15 54 NA NA NA NA NA NA NA 10529 FUN_015104 1851 818 607 1314 978 NA NA NA NA NA NA NA 10530 FUN_031960 2 8 25 57 11 ptg000023l:27153148-27154159 P49285 1.58e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) (CKA) Gallus gallus (Chicken) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0045820; GO:0046325; GO:1904408 10531 FUN_038548 510 304 447 482 241 NA NA NA NA NA NA NA 10532 FUN_038549 95 258 178 263 177 NA NA NA NA NA NA NA 10533 FUN_038547 898 769 426 716 687 ptg000027l:8536257-8541834 Q5U4T9 3.35e-30 Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (Leukocyte receptor cluster member 4) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) Xenopus laevis (African clawed frog) phosphatidylcholine acyl-chain remodeling [GO:0036151]; phosphatidylinositol acyl-chain remodeling [GO:0036149]; phosphatidylinositol biosynthetic process [GO:0006661]; regulation of triglyceride metabolic process [GO:0090207] GO:0005789; GO:0006661; GO:0008374; GO:0036149; GO:0036151; GO:0090207 10534 FUN_038544 1788 2249 1113 846 1141 NA NA NA NA NA NA NA 10535 FUN_038545 1217 1033 722 907 874 NA NA NA NA NA NA NA 10536 FUN_038542 286 331 124 310 202 ptg000027l:8516230-8517328 O15973 7.5e-33 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 10537 FUN_038543 0 0 0 0 48 NA NA NA NA NA NA NA 10538 FUN_038540 1779 1854 1160 1035 767 NA NA NA NA NA NA NA 10539 FUN_038541 586 395 163 482 1526 NA NA NA NA NA NA NA 10540 FUN_023336 3031 4186 1654 2616 2113 NA NA NA NA NA NA NA 10541 FUN_015819 0 10 18 0 25 NA NA NA NA NA NA NA 10542 FUN_015818 0 0 0 10 0 NA NA NA NA NA NA NA 10543 FUN_007201 12 1 31 4 203 NA NA NA NA NA NA NA 10544 FUN_027145 0 0 6 5 3 NA NA NA NA NA NA NA 10545 FUN_027142 2 1 1 9 2 NA NA NA NA NA NA NA 10546 FUN_027143 17 148 8 38 49 NA NA NA NA NA NA NA 10547 FUN_027140 493 1996 481 1279 1245 NA NA NA NA NA NA NA 10548 FUN_027141 0 690 31 358 29 NA NA NA NA NA NA NA 10549 FUN_006621 8006 7093 5710 14245 8328 NA NA NA NA NA NA NA 10550 FUN_023399 220 187 252 401 354 NA NA NA NA NA NA NA 10551 FUN_023249 4410 3748 2554 2908 2351 NA NA NA NA NA NA NA 10552 FUN_023248 394 276 232 194 272 NA NA NA NA NA NA NA 10553 FUN_023241 654 485 320 347 457 NA NA NA NA NA NA NA 10554 FUN_023240 4105 2989 1580 2728 2505 NA NA NA NA NA NA NA 10555 FUN_023243 972 708 404 979 412 NA NA NA NA NA NA NA 10556 FUN_023242 544 944 692 881 845 NA NA NA NA NA NA NA 10557 FUN_023245 579 452 197 560 246 NA NA NA NA NA NA NA 10558 FUN_023247 391 114 93 266 160 NA NA NA NA NA NA NA 10559 FUN_023246 118 256 224 358 105 ptg000017l:5461687-5495197 Q14191 7.71e-28 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000287; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000731; GO:0000781; GO:0003677; GO:0003678; GO:0003682; GO:0004527; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005813; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006284; GO:0006302; GO:0006310; GO:0006974; GO:0006979; GO:0007420; GO:0007568; GO:0008408; GO:0009267; GO:0009378; GO:0010225; GO:0010259; GO:0016607; GO:0016887; GO:0030145; GO:0031297; GO:0032201; GO:0032405; GO:0032508; GO:0040009; GO:0042803; GO:0043005; GO:0043138; GO:0044806; GO:0044877; GO:0051345; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0070337; GO:0071480; GO:0090398; GO:0090399; GO:0090656; GO:0098530; GO:1902570; GO:1905773 10560 FUN_023246 118 256 224 358 105 ptg000017l:5461687-5495197 Q14191 7.71e-28 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 3.6.4.12)] Homo sapiens (Human) aging [GO:0007568]; base-excision repair [GO:0006284]; brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; cellular response to starvation [GO:0009267]; cellular senescence [GO:0090398]; DNA duplex unwinding [GO:0032508]; DNA metabolic process [GO:0006259]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; G-quadruplex DNA unwinding [GO:0044806]; multicellular organism aging [GO:0010259]; positive regulation of hydrolase activity [GO:0051345]; positive regulation of strand invasion [GO:0098530]; protein localization to nucleolus [GO:1902570]; regulation of growth rate [GO:0040009]; replication fork processing [GO:0031297]; replicative senescence [GO:0090399]; response to oxidative stress [GO:0006979]; response to UV-C [GO:0010225]; t-circle formation [GO:0090656]; telomere maintenance [GO:0000723]; telomere maintenance via semi-conservative replication [GO:0032201]; telomeric D-loop disassembly [GO:0061820] GO:0000287; GO:0000400; GO:0000403; GO:0000405; GO:0000723; GO:0000724; GO:0000731; GO:0000781; GO:0003677; GO:0003678; GO:0003682; GO:0004527; GO:0005524; GO:0005634; GO:0005654; GO:0005657; GO:0005694; GO:0005730; GO:0005737; GO:0005813; GO:0006259; GO:0006260; GO:0006268; GO:0006281; GO:0006284; GO:0006302; GO:0006310; GO:0006974; GO:0006979; GO:0007420; GO:0007568; GO:0008408; GO:0009267; GO:0009378; GO:0010225; GO:0010259; GO:0016607; GO:0016887; GO:0030145; GO:0031297; GO:0032201; GO:0032405; GO:0032508; GO:0040009; GO:0042803; GO:0043005; GO:0043138; GO:0044806; GO:0044877; GO:0051345; GO:0051880; GO:0061749; GO:0061820; GO:0061821; GO:0061849; GO:0070337; GO:0071480; GO:0090398; GO:0090399; GO:0090656; GO:0098530; GO:1902570; GO:1905773 10561 FUN_018290 379 176 117 518 174 NA NA NA NA NA NA NA 10562 FUN_018291 472 59 125 196 267 NA NA NA NA NA NA NA 10563 FUN_018292 1100 532 738 3991 1156 NA NA NA NA NA NA NA 10564 FUN_018294 81 98 175 21 4 NA NA NA NA NA NA NA 10565 FUN_018295 0 0 0 0 134 NA NA NA NA NA NA NA 10566 FUN_018296 197 15 48 133 60 NA NA NA NA NA NA NA 10567 FUN_018297 224 20 187 310 295 ptg000012l:7322826-7334750 O89026 8.99e-21 Roundabout homolog 1 Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; endocardial cushion formation [GO:0003272]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; kidney development [GO:0001822]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; regulation of dendrite morphogenesis [GO:0048814]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281]; ventricular septum morphogenesis [GO:0060412] GO:0001822; GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0003281; GO:0005737; GO:0005886; GO:0006919; GO:0007156; GO:0007411; GO:0007507; GO:0008046; GO:0008285; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0021891; GO:0030275; GO:0030336; GO:0030424; GO:0030673; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043025; GO:0043406; GO:0048814; GO:0050772; GO:0050925; GO:0060412; GO:0060763; GO:0060976; GO:0070100; GO:1900748 10568 FUN_018298 1020 46 1012 518 413 NA NA NA NA NA NA NA 10569 FUN_018299 817 104 1345 460 494 NA NA NA NA NA NA NA 10570 FUN_033938 1677 1412 947 1203 846 NA NA NA NA NA NA NA 10571 FUN_033939 296 309 228 435 537 NA NA NA NA NA NA NA 10572 FUN_033936 25 67 62 45 30 ptg000024l:2891700-2893092 A0JC51 5.22e-70 Zinc finger protein ZIC 4 (XlZic4) (Zinc finger protein of the cerebellum 4) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 10573 FUN_039993 48 0 59 0 161 NA NA NA NA NA NA NA 10574 FUN_039990 2489 1860 1138 2108 1349 NA NA NA NA NA NA NA 10575 FUN_039991 20 0 0 0 0 NA NA NA NA NA NA NA 10576 FUN_033932 45 5 19 23 25 NA NA NA NA NA NA NA 10577 FUN_033933 184 73 55 98 54 ptg000024l:2822291-2823584 Q15915 1.2e-92 Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1) Homo sapiens (Human) adult walking behavior [GO:0007628]; brain development [GO:0007420]; cell differentiation [GO:0030154]; central nervous system development [GO:0007417]; hippocampus development [GO:0021766]; inner ear morphogenesis [GO:0042472]; maintenance of cell number [GO:0098727]; olfactory bulb development [GO:0021772]; pattern specification process [GO:0007389]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein import into nucleus [GO:0042307]; regulation of smoothened signaling pathway [GO:0008589]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord development [GO:0021510] GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0007389; GO:0007417; GO:0007420; GO:0007628; GO:0008589; GO:0021510; GO:0021766; GO:0021772; GO:0030154; GO:0042307; GO:0042472; GO:0045893; GO:0046872; GO:0098727; GO:1990837 10578 FUN_033930 63 74 112 27 88 ptg000024l:2786229-2788380 E7FAM5 1.13e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 10579 FUN_039995 257 0 9 0 5 NA NA NA NA NA NA NA 10580 FUN_018874 52 636 348 380 9 NA NA NA NA NA NA NA 10581 FUN_018870 296 381 64 236 425 NA NA NA NA NA NA NA 10582 FUN_018873 101 16 49 39 50 NA NA NA NA NA NA NA 10583 FUN_014440 720 520 196 529 554 ptg000009l:216864-223918 Q692V3 9.28e-47 Tetratricopeptide repeat protein 41 (TPR repeat protein 41) (Grp94-neighboring nucleotidase) Mus musculus (Mouse) NA GO:0005737 10584 FUN_013490 719 574 1532 835 1992 NA NA NA NA NA NA NA 10585 FUN_014446 8 0 0 0 18 NA NA NA NA NA NA NA 10586 FUN_001605 1173 416 738 674 413 NA NA NA NA NA NA NA 10587 FUN_007299 9 4 15 4 31 NA NA NA NA NA NA NA 10588 FUN_007294 7 0 0 0 0 NA NA NA NA NA NA NA 10589 FUN_007295 0 0 2 1 15 NA NA NA NA NA NA NA 10590 FUN_035426 489 752 810 1843 1494 NA NA NA NA NA NA NA 10591 FUN_035427 0 0 0 0 7 NA NA NA NA NA NA NA 10592 FUN_035424 3 0 12 4 12 NA NA NA NA NA NA NA 10593 FUN_035425 353 189 126 392 350 NA NA NA NA NA NA NA 10594 FUN_035422 230 127 109 274 99 NA NA NA NA NA NA NA 10595 FUN_035423 3024 3116 1274 2708 1662 NA NA NA NA NA NA NA 10596 FUN_035420 674 240 190 398 459 NA NA NA NA NA NA NA 10597 FUN_035421 134 17 33 58 67 NA NA NA NA NA NA NA 10598 FUN_042489 10 12 0 11 16 NA NA NA NA NA NA NA 10599 FUN_035428 61 209 80 390 178 NA NA NA NA NA NA NA 10600 FUN_035429 0 46 36 44 20 NA NA NA NA NA NA NA 10601 FUN_004901 452 366 347 545 351 NA NA NA NA NA NA NA 10602 FUN_004900 723 471 367 589 589 ntLink_8:28514120-28530575 P54098 3.07e-24 DNA polymerase subunit gamma-1 (EC 2.7.7.7) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha) Homo sapiens (Human) base-excision repair, gap-filling [GO:0006287]; DNA metabolic process [GO:0006259]; DNA-templated DNA replication [GO:0006261]; mitochondrial DNA replication [GO:0006264] GO:0002020; GO:0003677; GO:0003682; GO:0003887; GO:0005739; GO:0005759; GO:0005760; GO:0006259; GO:0006261; GO:0006264; GO:0006287; GO:0008408; GO:0032991; GO:0042645 10603 FUN_004903 13884 38146 8418 24744 11152 NA NA NA NA NA NA NA 10604 FUN_004902 30 225 83 213 132 NA NA NA NA NA NA NA 10605 FUN_004905 785 430 478 1358 1503 NA NA NA NA NA NA NA 10606 FUN_004904 1935 1357 834 1655 2006 NA NA NA NA NA NA NA 10607 FUN_004907 229 147 140 129 244 NA NA NA NA NA NA NA 10608 FUN_004906 268 127 119 249 184 NA NA NA NA NA NA NA 10609 FUN_004909 922 480 304 356 591 NA NA NA NA NA NA NA 10610 FUN_004908 346 386 295 374 374 ntLink_8:28611481-28614758 P56380 5.66e-39 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2) Mus musculus (Mouse) AMP biosynthetic process [GO:0006167]; apoptotic process [GO:0006915]; ATP biosynthetic process [GO:0006754] GO:0004081; GO:0005525; GO:0005739; GO:0006167; GO:0006754; GO:0006915 10611 FUN_000958 11 3 40 4 55 NA NA NA NA NA NA NA 10612 FUN_031505 857 829 476 532 227 NA NA NA NA NA NA NA 10613 FUN_031504 919 1486 1577 1697 1686 NA NA NA NA NA NA NA 10614 FUN_031507 1485 779 961 856 528 ptg000023l:22129719-22130955 H3ZPL1 2.84e-55 Aromatic-amino-acid aminotransferase 1 (ARAT-I) (AROAT) (EC 2.6.1.57) Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) biosynthetic process [GO:0009058] GO:0009058; GO:0030170; GO:0080130 10615 FUN_031506 1615 1363 838 1912 698 NA NA NA NA NA NA NA 10616 FUN_031503 595 435 579 1107 472 NA NA NA NA NA NA NA 10617 FUN_031502 2242 880 936 2073 1156 NA NA NA NA NA NA NA 10618 FUN_007037 108 88 61 88 204 ptg000001l:19602915-19702038 Q96MB7 5.21e-33 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 10619 FUN_031508 894 411 434 505 437 NA NA NA NA NA NA NA 10620 FUN_011435 0 0 7 0 10 NA NA NA NA NA NA NA 10621 FUN_043114 1215 1179 921 1290 550 NA NA NA NA NA NA NA 10622 FUN_043119 2980 2871 2513 4178 3383 NA NA NA NA NA NA NA 10623 FUN_000951 9 34 30 97 102 NA NA NA NA NA NA NA 10624 FUN_001993 461 0 0 0 0 NA NA NA NA NA NA NA 10625 FUN_001992 11 0 0 0 0 NA NA NA NA NA NA NA 10626 FUN_001995 3 5 0 28 0 NA NA NA NA NA NA NA 10627 FUN_029247 2140 1628 1082 1707 2151 NA NA NA NA NA NA NA 10628 FUN_020754 22 0 0 0 26 NA NA NA NA NA NA NA 10629 FUN_020755 0 6 12 2 90 NA NA NA NA NA NA NA 10630 FUN_020753 0 3 0 8 0 NA NA NA NA NA NA NA 10631 FUN_029246 2846 1031 1100 1680 1651 ptg000022l:9541522-9548932 Q28C33 2.2e-41 TBC1 domain family member 30 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 10632 FUN_000119 3 0 9 1 20 ntLink_4:165949-166712 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10633 FUN_000117 3 0 11 0 19 ntLink_4:161883-162646 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10634 FUN_000114 1 1 4 0 18 ntLink_4:153756-156324 P84239 4.97e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10635 FUN_000115 2 0 7 0 16 ntLink_4:157817-158580 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10636 FUN_000112 1 0 4 0 10 ntLink_4:149339-150118 P84239 4.85e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10637 FUN_000113 0 0 1 0 8 ntLink_4:151074-152269 P35061 7.49e-82 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10638 FUN_000110 4 0 10 1 13 ntLink_4:145647-146410 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10639 FUN_000111 0 0 0 0 7 ntLink_4:147025-148220 P35061 7.49e-82 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 10640 FUN_007768 4618 2229 721 2021 348 NA NA NA NA NA NA NA 10641 FUN_007769 0 0 0 0 13 NA NA NA NA NA NA NA 10642 FUN_007760 23356 29120 8792 10851 8226 NA NA NA NA NA NA NA 10643 FUN_007761 2428 1566 901 2282 1803 NA NA NA NA NA NA NA 10644 FUN_007762 2043 1161 787 1657 1181 NA NA NA NA NA NA NA 10645 FUN_007763 0 0 0 0 235 NA NA NA NA NA NA NA 10646 FUN_007766 265 56 140 169 184 NA NA NA NA NA NA NA 10647 FUN_007767 632 148 306 392 243 NA NA NA NA NA NA NA 10648 FUN_014847 607 288 512 713 777 NA NA NA NA NA NA NA 10649 FUN_005692 0 0 0 0 9 NA NA NA NA NA NA NA 10650 FUN_005690 0 0 1 0 7 NA NA NA NA NA NA NA 10651 FUN_005697 2276 1892 1187 2437 2530 NA NA NA NA NA NA NA 10652 FUN_005695 0 0 4 2 28 NA NA NA NA NA NA NA 10653 FUN_005698 182 170 123 355 254 NA NA NA NA NA NA NA 10654 FUN_005699 617 1025 699 684 547 NA NA NA NA NA NA NA 10655 FUN_013949 156 896 51 100 405 NA NA NA NA NA NA NA 10656 FUN_039309 22 51 0 128 25 NA NA NA NA NA NA NA 10657 FUN_033219 0 0 9 0 13 NA NA NA NA NA NA NA 10658 FUN_033213 2 0 26 18 44 NA NA NA NA NA NA NA 10659 FUN_033212 48 39 38 135 57 ptg000023l:41170339-41173272 D2CLZ9 2.91e-22 Transcription factor atoh8 (Atonal bHLH transcription factor 8) (Protein atonal homolog 8) Danio rerio (Zebrafish) (Brachydanio rerio) heart development [GO:0007507]; heart looping [GO:0001947]; neuron differentiation [GO:0030182]; regulation of neural retina development [GO:0061074]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; swim bladder formation [GO:0048797] GO:0000978; GO:0000981; GO:0001947; GO:0005634; GO:0005737; GO:0006357; GO:0007507; GO:0016607; GO:0030182; GO:0046983; GO:0048797; GO:0061074; GO:2001014 10660 FUN_033211 21 0 6 29 22 NA NA NA NA NA NA NA 10661 FUN_033210 2887 1507 1232 2072 885 NA NA NA NA NA NA NA 10662 FUN_033217 14 9 55 9 21 NA NA NA NA NA NA NA 10663 FUN_033216 1145 1100 604 1083 1023 NA NA NA NA NA NA NA 10664 FUN_033215 174 154 146 154 159 NA NA NA NA NA NA NA 10665 FUN_033214 965 743 676 1564 1277 NA NA NA NA NA NA NA 10666 FUN_004790 6 14 46 64 171 NA NA NA NA NA NA NA 10667 FUN_004791 699 733 434 1078 878 ntLink_8:27061825-27075075 P56706 1.63e-29 Protein Wnt-7b Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular oxygen homeostasis [GO:0032364]; cellular response to retinoic acid [GO:0071300]; central nervous system vasculogenesis [GO:0022009]; chorio-allantoic fusion [GO:0060710]; developmental growth involved in morphogenesis [GO:0060560]; embryonic organ development [GO:0048568]; embryonic placenta morphogenesis [GO:0060669]; establishment or maintenance of polarity of embryonic epithelium [GO:0016332]; fibroblast proliferation [GO:0048144]; forebrain regionalization [GO:0021871]; homeostatic process [GO:0042592]; in utero embryonic development [GO:0001701]; inner medullary collecting duct development [GO:0072061]; lens fiber cell development [GO:0070307]; lobar bronchus development [GO:0060482]; lung development [GO:0030324]; lung epithelium development [GO:0060428]; lung morphogenesis [GO:0060425]; mammary gland epithelium development [GO:0061180]; metanephric collecting duct development [GO:0072205]; metanephric epithelium development [GO:0072207]; metanephric loop of Henle development [GO:0072236]; metanephros morphogenesis [GO:0003338]; neuron differentiation [GO:0030182]; neuron projection morphogenesis [GO:0048812]; outer medullary collecting duct development [GO:0072060]; positive regulation of JNK cascade [GO:0046330]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of cell projection size [GO:0032536]; renal inner medulla development [GO:0072053]; renal outer medulla development [GO:0072054]; response to glucocorticoid [GO:0051384]; stem cell proliferation [GO:0072089]; synapse organization [GO:0050808]; trachea cartilage morphogenesis [GO:0060535]; Wnt signaling pathway [GO:0016055] GO:0001701; GO:0003338; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005788; GO:0005796; GO:0005886; GO:0016055; GO:0016332; GO:0021871; GO:0022009; GO:0030182; GO:0030324; GO:0030666; GO:0032364; GO:0032536; GO:0042592; GO:0045165; GO:0045669; GO:0046330; GO:0048018; GO:0048144; GO:0048568; GO:0048812; GO:0050808; GO:0051384; GO:0060070; GO:0060425; GO:0060428; GO:0060482; GO:0060535; GO:0060560; GO:0060669; GO:0060710; GO:0061180; GO:0070062; GO:0070307; GO:0071300; GO:0072053; GO:0072054; GO:0072060; GO:0072061; GO:0072089; GO:0072205; GO:0072207; GO:0072236 10668 FUN_004792 214 259 48 142 121 NA NA NA NA NA NA NA 10669 FUN_008349 93 30 48 48 140 ptg000002l:10669350-10670854 B3EX02 1.82e-31 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 10670 FUN_033647 52 3 0 0 89 NA NA NA NA NA NA NA 10671 FUN_008343 457 0 251 7 510 NA NA NA NA NA NA NA 10672 FUN_008341 52 17 0 81 126 ptg000002l:10584843-10586410 B8V7S0 1.08e-21 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 10673 FUN_008340 64 31 61 99 222 ptg000002l:10568265-10576923 B3EX02 2.69e-28 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 10674 FUN_008347 257 55 44 171 382 ptg000002l:10640601-10642105 B3EX02 1.01e-31 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 10675 FUN_008346 234 23 64 138 256 ptg000002l:10637917-10640164 B8V7S0 6.55e-22 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 10676 FUN_008345 351 116 133 375 388 ptg000002l:10624030-10633893 B3EX02 2.01e-50 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 10677 FUN_008345 351 116 133 375 388 ptg000002l:10624030-10633893 B3EX02 1.39e-29 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 10678 FUN_008344 54 0 94 43 69 NA NA NA NA NA NA NA 10679 FUN_009722 34 0 6 70 8 ptg000004l:10777841-10779008 Q96AY4 9.04e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10680 FUN_004796 261 477 117 278 361 NA NA NA NA NA NA NA 10681 FUN_039307 5 55 34 14 54 NA NA NA NA NA NA NA 10682 FUN_022000 29 0 34 94 92 NA NA NA NA NA NA NA 10683 FUN_016926 75 94 0 2 0 NA NA NA NA NA NA NA 10684 FUN_016923 0 0 0 17 0 NA NA NA NA NA NA NA 10685 FUN_016928 2 13 0 0 6 NA NA NA NA NA NA NA 10686 FUN_006419 0 15 0 0 0 NA NA NA NA NA NA NA 10687 FUN_006418 104 23 40 78 34 ptg000001l:12251056-12251903 Q9H4S2 3.35e-22 GS homeobox 1 (Homeobox protein GSH-1) Homo sapiens (Human) adenohypophysis development [GO:0021984]; central nervous system development [GO:0007417]; hypothalamus development [GO:0021854]; neuron differentiation [GO:0030182]; neuron fate commitment [GO:0048663]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spinal cord association neuron differentiation [GO:0021527]; transcription by RNA polymerase II [GO:0006366] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0006366; GO:0007417; GO:0021527; GO:0021854; GO:0021984; GO:0030182; GO:0043565; GO:0045944; GO:0048663; GO:1990837 10688 FUN_006411 527 299 377 554 762 NA NA NA NA NA NA NA 10689 FUN_006410 221 110 103 52 103 NA NA NA NA NA NA NA 10690 FUN_006413 37 210 126 280 135 ptg000001l:12196961-12198146 O54799 3.05e-25 Neuromedin-B receptor (NMB-R) (Neuromedin-B-preferring bombesin receptor) Mus musculus (Mouse) antiviral innate immune response [GO:0140374]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of interleukin-6 production [GO:0032715]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of osteoclast proliferation [GO:0090290]; positive regulation of respiratory gaseous exchange [GO:1903942]; sneeze reflex [GO:0160023] GO:0004930; GO:0004946; GO:0005829; GO:0005886; GO:0007186; GO:0008188; GO:0032715; GO:0032727; GO:0090290; GO:0140374; GO:0160023; GO:1903942 10691 FUN_006412 241 40 128 98 211 NA NA NA NA NA NA NA 10692 FUN_006415 7 4 29 3 68 NA NA NA NA NA NA NA 10693 FUN_006414 240 172 109 424 277 ptg000001l:12210392-12211193 Q0ZDF7 3.81e-50 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (OHCU decarboxylase) (EC 4.1.1.97) (Parahox neighbor) (Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase) Amia calva (Bowfin) allantoin metabolic process [GO:0000255]; purine nucleobase metabolic process [GO:0006144]; urate catabolic process [GO:0019628] GO:0000255; GO:0005777; GO:0006144; GO:0019628; GO:0051997 10694 FUN_006417 2518 2539 1327 2325 1680 NA NA NA NA NA NA NA 10695 FUN_006416 1156 898 832 1738 1681 ptg000001l:12221771-12236189 Q5BL81 7.2e-23 Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0006814; GO:0015293; GO:0016020 10696 FUN_004123 530 192 184 470 197 NA NA NA NA NA NA NA 10697 FUN_004122 1401 1990 984 2907 1642 ntLink_8:19540073-19559997 Q9D180 1.35e-44 Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65) Mus musculus (Mouse) NA NA 10698 FUN_004122 1401 1990 984 2907 1642 ntLink_8:19540073-19559997 Q9D180 2.66e-35 Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65) Mus musculus (Mouse) NA NA 10699 FUN_004122 1401 1990 984 2907 1642 ntLink_8:19540073-19559997 Q9D180 2.66e-35 Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65) Mus musculus (Mouse) NA NA 10700 FUN_004122 1401 1990 984 2907 1642 ntLink_8:19540073-19559997 Q9D180 7.15e-21 Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65) Mus musculus (Mouse) NA NA 10701 FUN_004121 4767 2424 1849 3892 2660 ntLink_8:19525772-19536749 Q7TNK7 2.74e-53 Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (CD antigen CD241) Rattus norvegicus (Rat) ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488]; carbon dioxide transport [GO:0015670]; cellular ion homeostasis [GO:0006873]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; multicellular organismal iron ion homeostasis [GO:0060586] GO:0005886; GO:0006873; GO:0008519; GO:0015670; GO:0016020; GO:0022840; GO:0030506; GO:0048821; GO:0060586; GO:0072488; GO:0097272; GO:0098662 10702 FUN_004121 4767 2424 1849 3892 2660 ntLink_8:19525772-19536749 Q7TNK7 2.74e-53 Ammonium transporter Rh type A (Erythrocyte membrane glycoprotein Rh50) (Rhesus blood group family type A glycoprotein) (Rh family type A glycoprotein) (Rh type A glycoprotein) (CD antigen CD241) Rattus norvegicus (Rat) ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488]; carbon dioxide transport [GO:0015670]; cellular ion homeostasis [GO:0006873]; erythrocyte development [GO:0048821]; inorganic cation transmembrane transport [GO:0098662]; multicellular organismal iron ion homeostasis [GO:0060586] GO:0005886; GO:0006873; GO:0008519; GO:0015670; GO:0016020; GO:0022840; GO:0030506; GO:0048821; GO:0060586; GO:0072488; GO:0097272; GO:0098662 10703 FUN_004120 22 0 15 40 43 ntLink_8:19520812-19521343 Q66IC8 3.75e-27 Dynein light chain Tctex-type 5 (Tctex1 domain-containing protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; microtubule-based movement [GO:0007018] GO:0005737; GO:0005868; GO:0007018; GO:0045505; GO:0060271 10704 FUN_004125 0 0 14 0 12 NA NA NA NA NA NA NA 10705 FUN_004124 132 154 86 152 124 NA NA NA NA NA NA NA 10706 FUN_004129 259 133 53 163 40 NA NA NA NA NA NA NA 10707 FUN_040366 4 65 0 0 0 NA NA NA NA NA NA NA 10708 FUN_028284 0 0 21 23 0 NA NA NA NA NA NA NA 10709 FUN_028286 326 102 605 461 589 NA NA NA NA NA NA NA 10710 FUN_028287 817 400 393 661 570 ptg000021l:17687326-17693728 Q8K1K9 1.15e-26 Histone H4 transcription factor (Histone nuclear factor P) (HiNF-P) (MBD2-interacting zinc finger protein) (Methyl-CpG-binding protein 2-interacting zinc finger protein) Mus musculus (Mouse) anatomical structure development [GO:0048856]; DNA damage checkpoint signaling [GO:0000077]; DNA repair [GO:0006281]; DNA-templated transcription [GO:0006351]; establishment of protein localization [GO:0045184]; G1/S transition of mitotic cell cycle [GO:0000082]; in utero embryonic development [GO:0001701]; myoblast differentiation [GO:0045445]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription involved in G1/S transition of mitotic cell cycle [GO:0000083] GO:0000077; GO:0000082; GO:0000083; GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001228; GO:0001701; GO:0003677; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006281; GO:0006351; GO:0006355; GO:0006357; GO:0010468; GO:0010628; GO:0010629; GO:0015030; GO:0019899; GO:0042393; GO:0045184; GO:0045445; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0048856 10711 FUN_028280 8 7 1121 2724 0 NA NA NA NA NA NA NA 10712 FUN_028281 46 28 30 93 59 NA NA NA NA NA NA NA 10713 FUN_028282 0 5 1072 2263 4 NA NA NA NA NA NA NA 10714 FUN_028283 0 19 0 11 0 ptg000021l:17632714-17643691 P04323 2.15e-63 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 10715 FUN_028288 1384 713 518 1666 1479 NA NA NA NA NA NA NA 10716 FUN_028289 23 28 6 13 18 NA NA NA NA NA NA NA 10717 FUN_034292 524 677 170 337 214 NA NA NA NA NA NA NA 10718 FUN_034293 124 81 121 196 74 NA NA NA NA NA NA NA 10719 FUN_034290 72 58 30 91 36 NA NA NA NA NA NA NA 10720 FUN_034291 371 503 152 349 232 NA NA NA NA NA NA NA 10721 FUN_034296 102 14 71 49 219 NA NA NA NA NA NA NA 10722 FUN_034297 749 1675 120 450 116 NA NA NA NA NA NA NA 10723 FUN_034294 532 280 183 266 209 NA NA NA NA NA NA NA 10724 FUN_034295 276 319 101 175 108 NA NA NA NA NA NA NA 10725 FUN_034298 883 592 407 874 596 NA NA NA NA NA NA NA 10726 FUN_034299 463 508 331 403 546 ptg000024l:7304635-7307206 Q6GPP1 5.35e-146 Telomere length regulation protein TEL2 homolog Xenopus laevis (African clawed frog) NA GO:0000781; GO:0005634; GO:0005737; GO:0016020 10727 FUN_001652 1073 664 445 888 845 NA NA NA NA NA NA NA 10728 FUN_013941 0 27 1 0 0 NA NA NA NA NA NA NA 10729 FUN_040989 0 10 7 0 15 NA NA NA NA NA NA NA 10730 FUN_040988 256 661 208 207 513 NA NA NA NA NA NA NA 10731 FUN_040981 0 0 0 0 15 NA NA NA NA NA NA NA 10732 FUN_040985 0 0 0 10 0 NA NA NA NA NA NA NA 10733 FUN_040987 2475 5097 1313 1947 2374 ptg000033l:910093-949627 Q9NBX4 3.09e-35 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 10734 FUN_040987 2475 5097 1313 1947 2374 ptg000033l:910093-949627 Q9NBX4 3.09e-35 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 10735 FUN_040986 167 42 21 69 79 NA NA NA NA NA NA NA 10736 FUN_026516 0 0 4 0 9 NA NA NA NA NA NA NA 10737 FUN_026517 37 29 44 151 139 ptg000020l:9992509-9993391 U3NEE3 6.91e-22 Carnosine N-methyltransferase 2 (EC 2.1.1.22) (Histamine N-methyltransferase-like) (HNMT-like) Gallus gallus (Chicken) carnosine metabolic process [GO:0035498]; methylation [GO:0032259] GO:0008170; GO:0030735; GO:0032259; GO:0035498 10738 FUN_011712 6 22 0 0 13 NA NA NA NA NA NA NA 10739 FUN_002407 90 7 149 54 3 NA NA NA NA NA NA NA 10740 FUN_002404 660 419 423 623 531 NA NA NA NA NA NA NA 10741 FUN_011711 477 511 301 352 455 ptg000008l:455673-457212 Q8C0L6 2.68e-76 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (EC 1.5.3.13) (Polyamine oxidase) Mus musculus (Mouse) polyamine catabolic process [GO:0006598]; positive regulation of spermidine biosynthetic process [GO:1901307]; putrescine biosynthetic process [GO:0009446]; putrescine catabolic process [GO:0009447]; spermidine catabolic process [GO:0046203]; spermine catabolic process [GO:0046208] GO:0005782; GO:0006598; GO:0009446; GO:0009447; GO:0016491; GO:0046203; GO:0046208; GO:0046592; GO:0052899; GO:0052901; GO:0052902; GO:0052903; GO:0052904; GO:1901307 10742 FUN_011716 135 29 109 149 88 NA NA NA NA NA NA NA 10743 FUN_002403 0 18 11 32 4 NA NA NA NA NA NA NA 10744 FUN_002400 247 0 0 0 0 NA NA NA NA NA NA NA 10745 FUN_011715 108 72 13 133 0 ptg000008l:471125-476771 P47742 8.7e-26 Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) Rattus norvegicus (Rat) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0004890; GO:0005231; GO:0005237; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007601; GO:0019904; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0098982; GO:1902476; GO:1902711; GO:1904315 10746 FUN_011718 57 105 66 69 309 ptg000008l:557452-558580 Q9EQD2 1.01e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 10747 FUN_011719 4 57 10 80 52 ptg000008l:562354-563581 F1R332 7.95e-29 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 10748 FUN_002408 630 54 871 183 99 NA NA NA NA NA NA NA 10749 FUN_002409 215 14 338 124 58 NA NA NA NA NA NA NA 10750 FUN_012357 13366 44508 12949 44912 15193 ptg000008l:8237328-8244387 O89114 7.81e-69 DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40) Mus musculus (Mouse) chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0005634; GO:0005829; GO:0051082; GO:0051085; GO:0051087 10751 FUN_012357 13366 44508 12949 44912 15193 ptg000008l:8237328-8244387 O89114 7.81e-69 DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40) Mus musculus (Mouse) chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0005634; GO:0005829; GO:0051082; GO:0051085; GO:0051087 10752 FUN_012356 1058 1077 518 1472 1940 NA NA NA NA NA NA NA 10753 FUN_012355 3486 2791 2171 3500 2788 NA NA NA NA NA NA NA 10754 FUN_012354 5 4 18 0 20 NA NA NA NA NA NA NA 10755 FUN_012353 3856 2862 2366 4431 3930 ptg000008l:8192109-8208063 O60341 1.47e-38 Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; DNA repair-dependent chromatin remodeling [GO:0140861]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992] GO:0000122; GO:0000380; GO:0000781; GO:0000785; GO:0002039; GO:0002052; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0006482; GO:0010569; GO:0010976; GO:0016491; GO:0019899; GO:0021987; GO:0030374; GO:0031398; GO:0032091; GO:0032451; GO:0032452; GO:0032453; GO:0032454; GO:0032880; GO:0032991; GO:0034644; GO:0034720; GO:0035563; GO:0042551; GO:0043392; GO:0043426; GO:0043433; GO:0043518; GO:0045793; GO:0045892; GO:0045944; GO:0046098; GO:0050660; GO:0050681; GO:0051091; GO:0051572; GO:0051573; GO:0055001; GO:0060765; GO:0060992; GO:0061629; GO:0061752; GO:0071320; GO:0071480; GO:0090308; GO:0120162; GO:0140297; GO:0140682; GO:0140861; GO:1902166; GO:1990391; GO:1990841; GO:2000179; GO:2000648 10756 FUN_012353 3856 2862 2366 4431 3930 ptg000008l:8192109-8208063 O60341 4.71e-37 Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; DNA repair-dependent chromatin remodeling [GO:0140861]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992] GO:0000122; GO:0000380; GO:0000781; GO:0000785; GO:0002039; GO:0002052; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0006482; GO:0010569; GO:0010976; GO:0016491; GO:0019899; GO:0021987; GO:0030374; GO:0031398; GO:0032091; GO:0032451; GO:0032452; GO:0032453; GO:0032454; GO:0032880; GO:0032991; GO:0034644; GO:0034720; GO:0035563; GO:0042551; GO:0043392; GO:0043426; GO:0043433; GO:0043518; GO:0045793; GO:0045892; GO:0045944; GO:0046098; GO:0050660; GO:0050681; GO:0051091; GO:0051572; GO:0051573; GO:0055001; GO:0060765; GO:0060992; GO:0061629; GO:0061752; GO:0071320; GO:0071480; GO:0090308; GO:0120162; GO:0140297; GO:0140682; GO:0140861; GO:1902166; GO:1990391; GO:1990841; GO:2000179; GO:2000648 10757 FUN_012353 3856 2862 2366 4431 3930 ptg000008l:8192109-8208063 O60341 2.24e-33 Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) Homo sapiens (Human) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to cAMP [GO:0071320]; cellular response to gamma radiation [GO:0071480]; cellular response to UV [GO:0034644]; cerebral cortex development [GO:0021987]; DNA repair-dependent chromatin remodeling [GO:0140861]; guanine metabolic process [GO:0046098]; histone H3-K4 demethylation [GO:0034720]; muscle cell development [GO:0055001]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K4 methylation [GO:0051572]; negative regulation of histone H3-K9 methylation [GO:0051573]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:1902166]; negative regulation of protein binding [GO:0032091]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron maturation [GO:0042551]; positive regulation of cell size [GO:0045793]; positive regulation of chromatin binding [GO:0035563]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron projection development [GO:0010976]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein demethylation [GO:0006482]; regulation of androgen receptor signaling pathway [GO:0060765]; regulation of DNA methylation-dependent heterochromatin formation [GO:0090308]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of protein localization [GO:0032880]; regulation of transcription by RNA polymerase II [GO:0006357]; response to fungicide [GO:0060992] GO:0000122; GO:0000380; GO:0000781; GO:0000785; GO:0002039; GO:0002052; GO:0003682; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0006482; GO:0010569; GO:0010976; GO:0016491; GO:0019899; GO:0021987; GO:0030374; GO:0031398; GO:0032091; GO:0032451; GO:0032452; GO:0032453; GO:0032454; GO:0032880; GO:0032991; GO:0034644; GO:0034720; GO:0035563; GO:0042551; GO:0043392; GO:0043426; GO:0043433; GO:0043518; GO:0045793; GO:0045892; GO:0045944; GO:0046098; GO:0050660; GO:0050681; GO:0051091; GO:0051572; GO:0051573; GO:0055001; GO:0060765; GO:0060992; GO:0061629; GO:0061752; GO:0071320; GO:0071480; GO:0090308; GO:0120162; GO:0140297; GO:0140682; GO:0140861; GO:1902166; GO:1990391; GO:1990841; GO:2000179; GO:2000648 10758 FUN_012352 18996 24352 10225 16882 13123 ptg000008l:8184297-8187338 O75953 9.05e-50 DnaJ homolog subfamily B member 5 (Heat shock protein Hsp40-2) (Heat shock protein Hsp40-3) (Heat shock protein cognate 40) (Hsc40) Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; response to unfolded protein [GO:0006986] GO:0005829; GO:0006986; GO:0051082; GO:0051085; GO:0051087 10759 FUN_012351 5857 5519 2091 1210 857 NA NA NA NA NA NA NA 10760 FUN_012350 6228 5857 2545 3067 1663 ptg000008l:8176270-8178667 Q5ZI57 2.06e-24 Trafficking protein particle complex subunit 3 Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891] GO:0005783; GO:0005829; GO:0006888; GO:0006891; GO:0030008; GO:0033106 10761 FUN_012359 19078 21215 14718 24119 15032 ptg000008l:8249586-8252261 Q9UDY4 1.42e-57 DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein) Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986] GO:0001671; GO:0005654; GO:0005829; GO:0005886; GO:0006986; GO:0009408; GO:0051082; GO:0051085; GO:0051087 10762 FUN_012359 19078 21215 14718 24119 15032 ptg000008l:8249586-8252261 Q9UDY4 1.15e-23 DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein) Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; response to heat [GO:0009408]; response to unfolded protein [GO:0006986] GO:0001671; GO:0005654; GO:0005829; GO:0005886; GO:0006986; GO:0009408; GO:0051082; GO:0051085; GO:0051087 10763 FUN_012358 113135 73170 29989 42798 17919 ptg000008l:8244896-8246283 Q24133 4.83e-102 DnaJ protein homolog 1 (DROJ1) Drosophila melanogaster (Fruit fly) chaperone cofactor-dependent protein refolding [GO:0051085]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of crystal cell differentiation [GO:0042691]; protein folding [GO:0006457]; protein stabilization [GO:0050821]; response to heat [GO:0009408] GO:0000122; GO:0005829; GO:0006457; GO:0009408; GO:0042691; GO:0050821; GO:0051082; GO:0051085; GO:0051087; GO:0140297 10764 FUN_013404 745 467 252 584 463 NA NA NA NA NA NA NA 10765 FUN_013405 1911 1373 1570 1013 1108 ptg000008l:22154206-22160944 O89110 1.34e-37 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to ethanol [GO:0045471]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0048738; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 10766 FUN_013406 647 965 489 811 709 NA NA NA NA NA NA NA 10767 FUN_013407 11 33 10 18 7 NA NA NA NA NA NA NA 10768 FUN_013400 21692 23130 11200 19864 15584 NA NA NA NA NA NA NA 10769 FUN_013401 10 27 0 13 0 ptg000008l:22102521-22105254 Q9NPF2 1.43e-62 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Homo sapiens (Human) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016020; GO:0016051; GO:0030166; GO:0030206; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0050659 10770 FUN_013402 1444 575 177 1228 850 NA NA NA NA NA NA NA 10771 FUN_013403 82 45 24 174 171 NA NA NA NA NA NA NA 10772 FUN_013408 191 92 128 89 105 NA NA NA NA NA NA NA 10773 FUN_013409 383 105 223 309 343 NA NA NA NA NA NA NA 10774 FUN_043180 2116 1745 1023 1462 1247 NA NA NA NA NA NA NA 10775 FUN_043181 912 1032 330 1063 720 NA NA NA NA NA NA NA 10776 FUN_043182 5188 3540 2466 3652 3758 NA NA NA NA NA NA NA 10777 FUN_000927 2736 4156 1527 2538 1525 NA NA NA NA NA NA NA 10778 FUN_000926 391 550 197 281 521 NA NA NA NA NA NA NA 10779 FUN_000925 704 508 330 358 225 NA NA NA NA NA NA NA 10780 FUN_000924 74 41 1 22 12 NA NA NA NA NA NA NA 10781 FUN_000922 2912 1922 1020 1828 1685 ntLink_6:6073546-6087614 P57769 1.18e-39 Sorting nexin-16 Rattus norvegicus (Rat) early endosome to late endosome transport [GO:0045022]; endosome to lysosome transport [GO:0008333]; protein targeting to lysosome [GO:0006622] GO:0005764; GO:0005769; GO:0005770; GO:0005829; GO:0006622; GO:0008333; GO:0031313; GO:0031901; GO:0031902; GO:0035091; GO:0042802; GO:0045022 10782 FUN_000921 286 167 84 304 174 NA NA NA NA NA NA NA 10783 FUN_000920 112 167 191 221 207 NA NA NA NA NA NA NA 10784 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.46e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10785 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 3.82e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10786 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 3.31e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10787 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 9.65e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10788 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.08e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10789 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 7.39e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10790 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.31e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10791 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.15e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10792 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 2.11e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10793 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.42e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10794 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.57e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10795 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 1.13e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10796 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 3.62e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10797 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 2.37e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10798 FUN_009757 0 102 0 142 125 ptg000004l:11195502-11204239 Q96AY4 7.36e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 10799 FUN_009756 0 30 0 28 57 NA NA NA NA NA NA NA 10800 FUN_009751 0 24 0 0 4 NA NA NA NA NA NA NA 10801 FUN_004838 544 145 109 206 293 ntLink_8:27707678-27715709 Q05941 1.36e-52 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 10802 FUN_015769 0 0 0 8 0 NA NA NA NA NA NA NA 10803 FUN_015766 8 0 0 0 28 NA NA NA NA NA NA NA 10804 FUN_015765 548 290 102 206 262 NA NA NA NA NA NA NA 10805 FUN_039793 3714 3131 1863 3490 2313 NA NA NA NA NA NA NA 10806 FUN_042275 21 0 9 0 31 NA NA NA NA NA NA NA 10807 FUN_042274 138 116 145 117 179 NA NA NA NA NA NA NA 10808 FUN_042277 16 22 6 10 3 NA NA NA NA NA NA NA 10809 FUN_042276 9 1 6 4 29 NA NA NA NA NA NA NA 10810 FUN_016151 3319 1787 2079 2991 2638 NA NA NA NA NA NA NA 10811 FUN_042270 548 652 581 693 1275 NA NA NA NA NA NA NA 10812 FUN_042273 121 53 99 64 117 NA NA NA NA NA NA NA 10813 FUN_023087 82 79 46 1 209 NA NA NA NA NA NA NA 10814 FUN_023086 603 256 447 570 737 NA NA NA NA NA NA NA 10815 FUN_023085 277 182 276 474 305 ptg000017l:3440535-3445425 O62809 8.34e-36 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Sus scrofa (Pig) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 10816 FUN_023084 21 0 24 0 55 NA NA NA NA NA NA NA 10817 FUN_016159 87 0 30 70 57 NA NA NA NA NA NA NA 10818 FUN_023082 815 586 681 536 293 ptg000017l:3415256-3418301 Q9WU47 1.32e-34 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005801; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0072542; GO:0090316 10819 FUN_023082 815 586 681 536 293 ptg000017l:3415256-3418301 Q9WU47 2.99e-30 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005801; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0072542; GO:0090316 10820 FUN_023081 457 715 377 244 274 NA NA NA NA NA NA NA 10821 FUN_023080 1305 1102 827 898 815 NA NA NA NA NA NA NA 10822 FUN_015495 194 189 135 158 89 NA NA NA NA NA NA NA 10823 FUN_015494 0 34 19 0 0 NA NA NA NA NA NA NA 10824 FUN_015497 0 0 0 17 2 NA NA NA NA NA NA NA 10825 FUN_015490 1312 642 417 777 433 NA NA NA NA NA NA NA 10826 FUN_008805 25 10 23 35 20 NA NA NA NA NA NA NA 10827 FUN_008807 26 0 10 15 25 NA NA NA NA NA NA NA 10828 FUN_008800 95 286 58 82 106 NA NA NA NA NA NA NA 10829 FUN_008801 99 143 128 320 159 NA NA NA NA NA NA NA 10830 FUN_008802 1492 690 169 875 590 NA NA NA NA NA NA NA 10831 FUN_008803 638 562 181 737 371 NA NA NA NA NA NA NA 10832 FUN_008808 0 0 0 0 10 NA NA NA NA NA NA NA 10833 FUN_008809 0 0 20 0 0 NA NA NA NA NA NA NA 10834 FUN_028503 2773 3120 2637 2476 1274 ptg000021l:20769053-20770053 Q923G2 3.85e-43 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (RPB17) (RPB8 homolog) Mus musculus (Mouse) transcription by RNA polymerase II [GO:0006366] GO:0003697; GO:0005634; GO:0005654; GO:0005665; GO:0005666; GO:0005736; GO:0006366; GO:0032993 10835 FUN_028501 25 23 0 577 50 NA NA NA NA NA NA NA 10836 FUN_026563 43 0 46 17 447 NA NA NA NA NA NA NA 10837 FUN_028506 2769 1577 1060 2372 2116 NA NA NA NA NA NA NA 10838 FUN_028505 349 271 196 375 281 ptg000021l:20794717-20798103 P97292 2.69e-22 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 10839 FUN_026560 0 0 38 0 43 NA NA NA NA NA NA NA 10840 FUN_028509 3281 2497 2209 2830 2424 NA NA NA NA NA NA NA 10841 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 4.58e-90 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10842 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 4.58e-90 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10843 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 4.58e-90 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10844 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 4.58e-90 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10845 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 5.11e-42 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10846 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 5.11e-42 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10847 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 5.11e-42 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10848 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 5.11e-42 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10849 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 1.83e-29 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10850 FUN_028508 15532 8636 5810 9310 8288 ptg000021l:20824940-20829890 Q66HB3 1.83e-29 Intraflagellar transport protein 80 homolog (WD repeat-containing protein 56) Rattus norvegicus (Rat) articular cartilage development [GO:0061975]; bone mineralization involved in bone maturation [GO:0035630]; bone morphogenesis [GO:0060349]; chondrocyte differentiation [GO:0002062]; cilium assembly [GO:0060271]; endochondral ossification [GO:0001958]; growth plate cartilage chondrocyte differentiation [GO:0003418]; growth plate cartilage development [GO:0003417]; keratinocyte proliferation [GO:0043616]; limb development [GO:0060173]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; non-canonical Wnt signaling pathway [GO:0035567]; non-motile cilium assembly [GO:1905515]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; receptor localization to non-motile cilium [GO:0097500]; skeletal system development [GO:0001501]; smoothened signaling pathway [GO:0007224] GO:0001501; GO:0001649; GO:0001958; GO:0002062; GO:0003417; GO:0003418; GO:0005737; GO:0005813; GO:0005929; GO:0007224; GO:0010839; GO:0030992; GO:0033687; GO:0035567; GO:0035630; GO:0036064; GO:0043616; GO:0050680; GO:0060173; GO:0060271; GO:0060349; GO:0061975; GO:0097500; GO:0097731; GO:1905515; GO:2000051 10851 FUN_026568 147 0 59 154 317 ptg000020l:10851752-10927725 P14381 2.71e-91 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 10852 FUN_025034 24 9 2 85 12 NA NA NA NA NA NA NA 10853 FUN_025036 8 0 0 0 12 NA NA NA NA NA NA NA 10854 FUN_025031 3173 3041 1716 1870 1786 NA NA NA NA NA NA NA 10855 FUN_022021 0 0 25 125 4 NA NA NA NA NA NA NA 10856 FUN_025039 0 0 0 0 29 NA NA NA NA NA NA NA 10857 FUN_017186 0 0 0 0 10 NA NA NA NA NA NA NA 10858 FUN_041618 603 500 144 429 446 ptg000035l:5949920-5956811 O15484 9.12e-31 Calpain-5 (EC 3.4.22.-) (Calpain htra-3) (New calpain 3) (nCL-3) Homo sapiens (Human) proteolysis [GO:0006508]; signal transduction [GO:0007165] GO:0004198; GO:0005737; GO:0005925; GO:0006508; GO:0007165; GO:0009986; GO:0045202; GO:0070062 10859 FUN_041619 84 29 17 42 7 NA NA NA NA NA NA NA 10860 FUN_041612 14 12 70 19 49 NA NA NA NA NA NA NA 10861 FUN_041613 34 0 5 40 0 NA NA NA NA NA NA NA 10862 FUN_041610 0 4 24 0 103 NA NA NA NA NA NA NA 10863 FUN_041611 1453 1013 673 1206 685 NA NA NA NA NA NA NA 10864 FUN_041616 3601 3751 1227 3177 1845 NA NA NA NA NA NA NA 10865 FUN_041617 7272 7308 2686 6625 5058 NA NA NA NA NA NA NA 10866 FUN_041614 0 0 0 2 35 NA NA NA NA NA NA NA 10867 FUN_042143 0 0 0 6 18 NA NA NA NA NA NA NA 10868 FUN_006340 0 0 0 0 76 NA NA NA NA NA NA NA 10869 FUN_031729 1082 391 451 712 774 NA NA NA NA NA NA NA 10870 FUN_006345 0 0 0 9 0 NA NA NA NA NA NA NA 10871 FUN_042146 0 0 0 0 12 NA NA NA NA NA NA NA 10872 FUN_006347 14 0 0 0 9 NA NA NA NA NA NA NA 10873 FUN_014171 44 17 68 5 326 NA NA NA NA NA NA NA 10874 FUN_014170 2523 1384 1631 2662 1481 NA NA NA NA NA NA NA 10875 FUN_014172 12 73 9 14 39 NA NA NA NA NA NA NA 10876 FUN_014175 7 0 2 0 1 NA NA NA NA NA NA NA 10877 FUN_014174 27 0 51 0 171 NA NA NA NA NA NA NA 10878 FUN_014177 0 0 1 0 26 NA NA NA NA NA NA NA 10879 FUN_014176 21 5 14 5 55 NA NA NA NA NA NA NA 10880 FUN_014179 838 644 45 44 5 NA NA NA NA NA NA NA 10881 FUN_014178 0 0 0 0 10 NA NA NA NA NA NA NA 10882 FUN_009499 21 0 0 0 0 NA NA NA NA NA NA NA 10883 FUN_011508 0 0 0 0 7 NA NA NA NA NA NA NA 10884 FUN_024403 300 72 80 275 121 ptg000018l:5862478-5866684 Q8JZQ5 1.13e-142 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Mus musculus (Mouse) amiloride transport [GO:0015898]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0015898; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097159; GO:0097185 10885 FUN_024077 0 0 0 18 19 ptg000018l:1977147-1978448 Q96P65 1.77e-21 Pyroglutamylated RF-amide peptide receptor (AQ27) (G-protein coupled receptor 103) (Orexigenic neuropeptide QRFP receptor) (SP9155) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0016020 10886 FUN_024076 100 60 128 200 51 NA NA NA NA NA NA NA 10887 FUN_024075 3047 2564 1543 3124 1532 NA NA NA NA NA NA NA 10888 FUN_024074 2433 1102 708 1897 1363 NA NA NA NA NA NA NA 10889 FUN_024073 30 53 22 27 4 NA NA NA NA NA NA NA 10890 FUN_024072 180 32 38 56 117 NA NA NA NA NA NA NA 10891 FUN_024071 79 35 13 55 24 NA NA NA NA NA NA NA 10892 FUN_024070 0 0 5 25 5 NA NA NA NA NA NA NA 10893 FUN_029406 3807 2198 1020 1903 4619 ptg000023l:1562745-1564332 P15870 1.96e-21 Histone H1-delta Strongylocentrotus purpuratus (Purple sea urchin) chromosome condensation [GO:0030261]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334] GO:0000786; GO:0003690; GO:0005634; GO:0006334; GO:0030261; GO:0030527; GO:0031492; GO:0045910 10894 FUN_011430 18 20 10 4 31 NA NA NA NA NA NA NA 10895 FUN_023869 104 3 10 94 47 NA NA NA NA NA NA NA 10896 FUN_023868 304 51 63 149 221 NA NA NA NA NA NA NA 10897 FUN_031749 71 0 0 64 60 ptg000023l:24974130-24977057 Q5TZE1 1.86e-59 BTB/POZ domain-containing protein 6-B Danio rerio (Zebrafish) (Brachydanio rerio) neurogenesis [GO:0022008] GO:0005634; GO:0005829; GO:0022008 10898 FUN_031748 2072 2740 883 3321 2248 NA NA NA NA NA NA NA 10899 FUN_031742 392 339 139 174 104 NA NA NA NA NA NA NA 10900 FUN_023863 0 0 0 0 6 NA NA NA NA NA NA NA 10901 FUN_031740 86 110 16 112 66 NA NA NA NA NA NA NA 10902 FUN_023864 0 0 8 0 3 NA NA NA NA NA NA NA 10903 FUN_031745 0 0 7 22 5 ptg000023l:24940796-24941785 G3M4F8 3.8e-23 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 10904 FUN_039516 0 22 3 0 47 ptg000030l:949321-969540 P14381 6.46e-101 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 10905 FUN_039517 0 0 0 0 42 NA NA NA NA NA NA NA 10906 FUN_039512 35 0 69 68 6 NA NA NA NA NA NA NA 10907 FUN_039513 23 109 49 56 80 NA NA NA NA NA NA NA 10908 FUN_039510 18 0 14 0 71 NA NA NA NA NA NA NA 10909 FUN_039511 9 1 57 0 310 NA NA NA NA NA NA NA 10910 FUN_012603 0 19 0 0 0 NA NA NA NA NA NA NA 10911 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 3.85e-42 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10912 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 1.36e-39 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10913 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 2.87e-34 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10914 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 8.69e-30 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10915 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 2.47e-24 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10916 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 3.67e-22 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10917 FUN_008237 3470 3044 1968 4173 3403 ptg000002l:9549733-9562655 Q29RK2 8.55e-22 Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB) Bos taurus (Bovine) gluconeogenesis [GO:0006094]; lipid metabolic process [GO:0006629]; NADH metabolic process [GO:0006734]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral process [GO:0044794]; pyruvate metabolic process [GO:0006090]; viral release from host cell [GO:0019076]; viral RNA genome packaging [GO:0019074] GO:0004736; GO:0005524; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0006090; GO:0006094; GO:0006629; GO:0006734; GO:0006739; GO:0010629; GO:0019074; GO:0019076; GO:0042802; GO:0044794; GO:0046872 10918 FUN_032589 41 32 0 0 156 NA NA NA NA NA NA NA 10919 FUN_039695 0 3 9 0 10 ptg000030l:2535953-2543644 P0CT43 1.12e-74 Transposon Tf2-8 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 10920 FUN_006651 212 166 90 190 430 NA NA NA NA NA NA NA 10921 FUN_017232 9 0 14 11 22 NA NA NA NA NA NA NA 10922 FUN_006657 898 487 575 534 710 NA NA NA NA NA NA NA 10923 FUN_017230 62 0 0 0 0 NA NA NA NA NA NA NA 10924 FUN_008232 2276 2789 1210 2279 1418 ptg000002l:9517273-9519034 Q7SYS9 6.88e-25 Histamine N-methyltransferase B (HMT B) (EC 2.1.1.8) Xenopus laevis (African clawed frog) histamine catabolic process [GO:0001695]; methylation [GO:0032259] GO:0001695; GO:0005737; GO:0032259; GO:0046539 10925 FUN_006655 392 339 176 278 251 NA NA NA NA NA NA NA 10926 FUN_006654 1387 942 698 911 1153 ptg000001l:15207455-15228273 Q8IZU2 1.65e-67 WD repeat-containing protein 17 Homo sapiens (Human) NA NA 10927 FUN_026918 612 298 278 731 567 NA NA NA NA NA NA NA 10928 FUN_026916 314 347 384 369 355 NA NA NA NA NA NA NA 10929 FUN_026917 4145 2785 1871 1961 1760 ptg000020l:14877432-14898841 Q9N0E7 6.41e-73 Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] GO:0006777; GO:0008265; GO:0016829; GO:0030151; GO:0030170; GO:0043545; GO:0102867 10930 FUN_026917 4145 2785 1871 1961 1760 ptg000020l:14877432-14898841 Q9N0E7 1.38e-31 Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] GO:0006777; GO:0008265; GO:0016829; GO:0030151; GO:0030170; GO:0043545; GO:0102867 10931 FUN_026917 4145 2785 1871 1961 1760 ptg000020l:14877432-14898841 Q9N0E7 1.92e-22 Molybdenum cofactor sulfurase (MCS) (MOS) (MoCo sulfurase) (EC 2.8.1.9) (Molybdenum cofactor sulfurtransferase) Bos taurus (Bovine) Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdopterin cofactor metabolic process [GO:0043545] GO:0006777; GO:0008265; GO:0016829; GO:0030151; GO:0030170; GO:0043545; GO:0102867 10932 FUN_026912 13 0 0 0 0 NA NA NA NA NA NA NA 10933 FUN_026913 1995 1732 1002 1452 1383 NA NA NA NA NA NA NA 10934 FUN_033660 0 1 3 2 12 NA NA NA NA NA NA NA 10935 FUN_006936 1297 1169 471 898 1275 NA NA NA NA NA NA NA 10936 FUN_006658 3859 1069 1296 2057 2545 ptg000001l:15261471-15305365 P14381 1.83e-145 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 10937 FUN_006658 3859 1069 1296 2057 2545 ptg000001l:15261471-15305365 P14381 1.83e-145 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 10938 FUN_016411 232 269 120 326 238 NA NA NA NA NA NA NA 10939 FUN_006934 664 493 406 660 361 ptg000001l:18489819-18491094 Q6DBY9 9.57e-31 Carbohydrate sulfotransferase 1 (EC 2.8.2.21) (Keratan sulfate Gal-6 sulfotransferase) (KS6ST) (KSGal6ST) (KSST) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate metabolic process [GO:0005975]; keratan sulfate metabolic process [GO:0042339]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0042339; GO:0045130 10940 FUN_011437 3 0 12 6 13 NA NA NA NA NA NA NA 10941 FUN_006935 2438 4541 1312 1759 1275 NA NA NA NA NA NA NA 10942 FUN_008239 2248 1516 1679 1418 1393 NA NA NA NA NA NA NA 10943 FUN_006932 0 50 14 116 106 NA NA NA NA NA NA NA 10944 FUN_032587 16 20 6 112 446 NA NA NA NA NA NA NA 10945 FUN_006933 71 105 124 144 173 NA NA NA NA NA NA NA 10946 FUN_006930 295 210 172 438 517 ptg000001l:18432732-18469418 P0C6B8 1.51e-39 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10947 FUN_006930 295 210 172 438 517 ptg000001l:18432732-18469418 P0C6B8 1.16e-30 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10948 FUN_006930 295 210 172 438 517 ptg000001l:18432732-18469418 P0C6B8 2.53e-25 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 10949 FUN_006931 69 73 26 199 112 NA NA NA NA NA NA NA 10950 FUN_003519 18 0 14 0 0 NA NA NA NA NA NA NA 10951 FUN_003834 0 23 0 18 0 NA NA NA NA NA NA NA 10952 FUN_003835 0 8 0 18 0 NA NA NA NA NA NA NA 10953 FUN_031428 26 84 11 0 19 NA NA NA NA NA NA NA 10954 FUN_037370 6 3 0 16 2 NA NA NA NA NA NA NA 10955 FUN_037371 6 0 36 0 10 NA NA NA NA NA NA NA 10956 FUN_004825 5 21 0 37 0 NA NA NA NA NA NA NA 10957 FUN_037374 65 34 66 74 43 NA NA NA NA NA NA NA 10958 FUN_037376 117 50 63 45 124 NA NA NA NA NA NA NA 10959 FUN_042999 197 29 85 154 89 NA NA NA NA NA NA NA 10960 FUN_037378 208 118 87 73 74 NA NA NA NA NA NA NA 10961 FUN_003830 23 0 0 21 7 NA NA NA NA NA NA NA 10962 FUN_003831 23 0 0 25 5 NA NA NA NA NA NA NA 10963 FUN_005450 13 17 0 0 29 NA NA NA NA NA NA NA 10964 FUN_005452 14 1 4 0 160 NA NA NA NA NA NA NA 10965 FUN_005453 34 12 0 13 46 NA NA NA NA NA NA NA 10966 FUN_005454 16130 7674 8489 9155 7812 ntLink_8:35465147-35470674 P24367 3.26e-31 Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) Gallus gallus (Chicken) chaperone-mediated protein folding [GO:0061077]; negative regulation of collagen fibril organization [GO:1904027]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005737; GO:0005788; GO:0006457; GO:0016018; GO:0032991; GO:0042470; GO:0043231; GO:0061077; GO:1904027 10967 FUN_003832 16 110 0 89 0 NA NA NA NA NA NA NA 10968 FUN_005457 5 5 0 0 8 NA NA NA NA NA NA NA 10969 FUN_003833 0 37 0 20 0 NA NA NA NA NA NA NA 10970 FUN_001520 0 37 19 0 49 NA NA NA NA NA NA NA 10971 FUN_001521 306 252 131 321 165 ntLink_6:13199811-13200801 O88854 6.02e-23 Galanin receptor type 2 (GAL2-R) (GALR-2) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; G protein-coupled receptor signaling pathway [GO:0007186]; galanin-activated signaling pathway [GO:0090663]; inositol phosphate metabolic process [GO:0043647]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron projection development [GO:0031175]; neuropeptide signaling pathway [GO:0007218]; phosphatidylinositol metabolic process [GO:0046488]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of large conductance calcium-activated potassium channel activity [GO:1902608]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0004966; GO:0005886; GO:0005929; GO:0007186; GO:0007188; GO:0007189; GO:0007194; GO:0007200; GO:0007204; GO:0007218; GO:0008528; GO:0017046; GO:0031175; GO:0042923; GO:0043647; GO:0045944; GO:0046488; GO:0090663; GO:1902608 10972 FUN_001522 3117 2955 1815 1775 962 NA NA NA NA NA NA NA 10973 FUN_001523 515 1986 549 776 655 NA NA NA NA NA NA NA 10974 FUN_001524 323 615 502 1022 866 NA NA NA NA NA NA NA 10975 FUN_001525 174 190 67 141 304 NA NA NA NA NA NA NA 10976 FUN_031423 264 63 154 186 386 ptg000023l:21053352-21064751 Q7RTR2 1.77e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10977 FUN_031423 264 63 154 186 386 ptg000023l:21053352-21064751 Q7RTR2 3.86e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10978 FUN_031423 264 63 154 186 386 ptg000023l:21053352-21064751 Q7RTR2 7.97e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10979 FUN_031423 264 63 154 186 386 ptg000023l:21053352-21064751 Q7RTR2 2.72e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10980 FUN_001528 62 229 83 91 27 ntLink_6:13268616-13269735 Q9EQD2 1.87e-26 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 10981 FUN_001529 2319 1972 1574 2674 1843 NA NA NA NA NA NA NA 10982 FUN_031420 0 0 8 0 24 NA NA NA NA NA NA NA 10983 FUN_031728 1424 4 0 3 0 NA NA NA NA NA NA NA 10984 FUN_004725 470 405 305 119 155 NA NA NA NA NA NA NA 10985 FUN_031421 7 4 4 4 2 NA NA NA NA NA NA NA 10986 FUN_003838 1303 397 465 712 159 NA NA NA NA NA NA NA 10987 FUN_004727 9 19 0 19 36 NA NA NA NA NA NA NA 10988 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 2.39e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10989 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 5.54e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10990 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 3.07e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10991 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 7.55e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10992 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 7.82e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10993 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 7.48e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10994 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 9.63e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10995 FUN_031427 112 499 50 11 139 ptg000023l:21234269-21247113 Q7RTR2 1.12e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 10996 FUN_004721 1689 1145 929 2602 1703 NA NA NA NA NA NA NA 10997 FUN_004829 86 1058 1258 1321 563 NA NA NA NA NA NA NA 10998 FUN_023849 0 0 0 0 7 NA NA NA NA NA NA NA 10999 FUN_004720 666 512 407 664 668 ntLink_8:26228988-26229525 B1WB17 8.33e-29 Partner of Y14 and mago (PYM homolog 1 exon junction complex-associated factor) (Protein wibg homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) exon-exon junction complex disassembly [GO:1903259]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of translation [GO:0045727] GO:0000184; GO:0005654; GO:0005730; GO:0005737; GO:0035145; GO:0043022; GO:0045727; GO:1903259 11000 FUN_037749 178 143 126 196 161 NA NA NA NA NA NA NA 11001 FUN_023848 7 0 13 4 16 NA NA NA NA NA NA NA 11002 FUN_026008 3089 1014 1370 4759 4116 NA NA NA NA NA NA NA 11003 FUN_026009 2760 4582 4390 23657 16672 NA NA NA NA NA NA NA 11004 FUN_037748 80 10 67 90 199 NA NA NA NA NA NA NA 11005 FUN_026004 104 157 1104 54 64 ptg000020l:3192756-3200197 P59046 8.53e-29 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 11006 FUN_026005 0 0 7 0 0 NA NA NA NA NA NA NA 11007 FUN_026006 0 75 47 83 9 NA NA NA NA NA NA NA 11008 FUN_026007 20302 8517 657 12390 12400 NA NA NA NA NA NA NA 11009 FUN_026000 0 0 0 6 0 NA NA NA NA NA NA NA 11010 FUN_026001 103 27 61 75 48 ptg000020l:3148023-3150968 Q86WI3 7.14e-25 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 11011 FUN_026002 478 160 139 209 213 ptg000020l:3169012-3173383 Q8K3Z0 1.66e-34 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 11012 FUN_026003 0 0 53 0 0 NA NA NA NA NA NA NA 11013 FUN_004321 1107 281 326 1451 1791 ntLink_8:21895100-21895553 P54357 1.17e-29 Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain) Drosophila melanogaster (Fruit fly) actin filament-based movement [GO:0030048] GO:0005509; GO:0005829; GO:0016460; GO:0017022; GO:0030048; GO:0031475; GO:0031476; GO:0031477; GO:0032036 11014 FUN_004320 23 0 0 22 0 NA NA NA NA NA NA NA 11015 FUN_004323 177 103 56 465 163 NA NA NA NA NA NA NA 11016 FUN_018774 76 35 21 73 1151 ptg000012l:13280443-13295961 Q09575 4.96e-65 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11017 FUN_018774 76 35 21 73 1151 ptg000012l:13280443-13295961 Q09575 4.09e-43 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11018 FUN_018774 76 35 21 73 1151 ptg000012l:13280443-13295961 Q09575 4.09e-43 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11019 FUN_004325 15 3 12 0 7 NA NA NA NA NA NA NA 11020 FUN_004324 5233 4780 2745 4632 3338 NA NA NA NA NA NA NA 11021 FUN_004327 10 0 0 0 0 NA NA NA NA NA NA NA 11022 FUN_004326 33 25 12 31 33 NA NA NA NA NA NA NA 11023 FUN_004329 250 186 242 432 684 NA NA NA NA NA NA NA 11024 FUN_004328 0 0 0 8 21 NA NA NA NA NA NA NA 11025 FUN_040788 0 0 0 1 23 NA NA NA NA NA NA NA 11026 FUN_034050 4781 2981 2371 2647 2324 NA NA NA NA NA NA NA 11027 FUN_034051 956 1263 551 1214 1133 NA NA NA NA NA NA NA 11028 FUN_018483 72 69 77 125 48 NA NA NA NA NA NA NA 11029 FUN_034053 883 640 272 564 681 NA NA NA NA NA NA NA 11030 FUN_034056 40 0 20 44 39 NA NA NA NA NA NA NA 11031 FUN_034057 2593 1567 1134 2909 1448 NA NA NA NA NA NA NA 11032 FUN_034059 1012 1068 400 444 449 ptg000024l:4283507-4294313 Q3MV19 6.64e-39 TNF receptor-associated factor 6-A (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6-A) Xenopus laevis (African clawed frog) activation of NF-kappaB-inducing kinase activity [GO:0007250]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005938; GO:0007250; GO:0008270; GO:0042981; GO:0043122; GO:0070534 11033 FUN_000987 35 0 23 75 46 NA NA NA NA NA NA NA 11034 FUN_019285 9 7 14 4 14 NA NA NA NA NA NA NA 11035 FUN_019282 11 0 48 0 26 NA NA NA NA NA NA NA 11036 FUN_019283 0 0 7 4 15 NA NA NA NA NA NA NA 11037 FUN_007148 4064 2722 1900 3920 2768 ptg000001l:21008594-21017846 Q8NA54 8.24e-31 IQ and ubiquitin-like domain-containing protein Homo sapiens (Human) cilium assembly [GO:0060271]; smoothened signaling pathway [GO:0007224] GO:0001669; GO:0007224; GO:0031514; GO:0060271 11038 FUN_007149 92 74 37 41 74 NA NA NA NA NA NA NA 11039 FUN_007140 1468 1334 587 2064 1194 NA NA NA NA NA NA NA 11040 FUN_007141 1078 670 627 794 926 NA NA NA NA NA NA NA 11041 FUN_007142 148 82 103 161 127 NA NA NA NA NA NA NA 11042 FUN_007143 1919 1030 869 1596 1257 NA NA NA NA NA NA NA 11043 FUN_007144 1124 915 405 1079 658 NA NA NA NA NA NA NA 11044 FUN_007147 6558 4871 3770 7385 7938 NA NA NA NA NA NA NA 11045 FUN_006895 3 0 26 24 25 NA NA NA NA NA NA NA 11046 FUN_006894 127 672 550 596 652 NA NA NA NA NA NA NA 11047 FUN_006897 0 0 116 287 289 NA NA NA NA NA NA NA 11048 FUN_006896 26 19 104 168 204 NA NA NA NA NA NA NA 11049 FUN_006890 151 721 750 414 339 NA NA NA NA NA NA NA 11050 FUN_006893 30 34 0 27 0 NA NA NA NA NA NA NA 11051 FUN_034946 869 302 368 388 622 NA NA NA NA NA NA NA 11052 FUN_034947 496 258 212 268 297 NA NA NA NA NA NA NA 11053 FUN_034944 54 26 50 28 80 NA NA NA NA NA NA NA 11054 FUN_034945 2232 1084 847 1355 1306 NA NA NA NA NA NA NA 11055 FUN_034942 642 489 430 329 494 NA NA NA NA NA NA NA 11056 FUN_034943 201 290 230 215 196 NA NA NA NA NA NA NA 11057 FUN_034940 1960 1668 1245 1440 1214 NA NA NA NA NA NA NA 11058 FUN_034941 236 82 109 134 241 NA NA NA NA NA NA NA 11059 FUN_034948 638 567 524 502 375 ptg000025l:2025005-2027598 F6QEU4 3.54e-118 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 11060 FUN_034949 91 102 44 35 18 ptg000025l:2028581-2030351 Q5BIM1 1.57e-37 Tripartite motif-containing protein 45 Bos taurus (Bovine) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 11061 FUN_035099 1405 552 537 82 534 ptg000025l:3820019-3830510 Q9EQN5 6.57e-27 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Antifreeze enhancer-binding protein ortholog) (AEP) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process [GO:0050905]; RNA secondary structure unwinding [GO:0010501]; spinal cord motor neuron differentiation [GO:0021522] GO:0000049; GO:0000122; GO:0003677; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005737; GO:0008094; GO:0008186; GO:0008270; GO:0010501; GO:0016887; GO:0021522; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043025; GO:0043139; GO:0043621; GO:0048471; GO:0050905; GO:1990904; GO:1990955 11062 FUN_035099 1405 552 537 82 534 ptg000025l:3820019-3830510 Q9EQN5 7.2e-24 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Antifreeze enhancer-binding protein ortholog) (AEP) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process [GO:0050905]; RNA secondary structure unwinding [GO:0010501]; spinal cord motor neuron differentiation [GO:0021522] GO:0000049; GO:0000122; GO:0003677; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005737; GO:0008094; GO:0008186; GO:0008270; GO:0010501; GO:0016887; GO:0021522; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043025; GO:0043139; GO:0043621; GO:0048471; GO:0050905; GO:1990904; GO:1990955 11063 FUN_035093 2820 2068 1539 3058 2402 ptg000025l:3703178-3718576 Q5JWF2 4.85e-23 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas) Homo sapiens (Human) adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; bone development [GO:0060348]; developmental growth [GO:0048589]; platelet aggregation [GO:0070527]; positive regulation of cold-induced thermogenesis [GO:0120162]; sensory perception of chemical stimulus [GO:0007606] GO:0001664; GO:0003924; GO:0005159; GO:0005525; GO:0005829; GO:0005834; GO:0007188; GO:0007189; GO:0007191; GO:0007606; GO:0010856; GO:0016020; GO:0016324; GO:0031683; GO:0031698; GO:0031748; GO:0031852; GO:0035255; GO:0046872; GO:0048589; GO:0051430; GO:0060348; GO:0070062; GO:0070527; GO:0120162 11064 FUN_035092 61 188 47 165 108 ptg000025l:3690874-3695607 Q96CG8 6.46e-28 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 11065 FUN_035091 400 497 117 96 261 ptg000025l:3676948-3682551 Q9CPW0 1.74e-76 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Mus musculus (Mouse) action potential initiation [GO:0099610]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; central nervous system myelination [GO:0022010]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle [GO:0042745]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite arborization [GO:0140059]; dendritic spine development [GO:0060996]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; embryonic brain development [GO:1990403]; ERK1 and ERK2 cascade [GO:0070371]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; glial cell proliferation [GO:0014009]; glutamatergic neuron differentiation [GO:1905962]; grooming behavior [GO:0007625]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; inhibitory chemical synaptic transmission [GO:0098977]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; limbic system development [GO:0021761]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; maintenance of synapse structure [GO:0099558]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; myelination [GO:0042552]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neural precursor cell proliferation [GO:0061351]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; neuronal action potential [GO:0019228]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuronal action potential [GO:1904457]; postsynaptic density organization [GO:0097106]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein localization to juxtaparanode region of axon [GO:0071205]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to dietary excess [GO:0002021]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to interleukin-17 [GO:0097396]; response to light intensity [GO:0009642]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to odorant [GO:1990834]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; rhythmic behavior [GO:0007622]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]; walking behavior [GO:0090659] GO:0000902; GO:0001701; GO:0002021; GO:0005769; GO:0005794; GO:0006954; GO:0007005; GO:0007155; GO:0007268; GO:0007409; GO:0007612; GO:0007622; GO:0007625; GO:0007626; GO:0008038; GO:0008076; GO:0008104; GO:0008283; GO:0008306; GO:0009408; GO:0009410; GO:0009612; GO:0009642; GO:0009725; GO:0009986; GO:0010033; GO:0010467; GO:0014009; GO:0016020; GO:0019226; GO:0019228; GO:0019899; GO:0021549; GO:0021692; GO:0021761; GO:0022010; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0031929; GO:0032229; GO:0033010; GO:0035176; GO:0035264; GO:0035556; GO:0042297; GO:0042552; GO:0042734; GO:0042745; GO:0043005; GO:0043025; GO:0043194; GO:0043491; GO:0044224; GO:0044309; GO:0044853; GO:0045163; GO:0045202; GO:0045444; GO:0045475; GO:0048265; GO:0048266; GO:0048787; GO:0048812; GO:0050884; GO:0050905; GO:0060076; GO:0060079; GO:0060996; GO:0061351; GO:0061744; GO:0070371; GO:0071205; GO:0071625; GO:0090659; GO:0097061; GO:0097062; GO:0097106; GO:0097396; GO:0098529; GO:0098793; GO:0098794; GO:0098976; GO:0098977; GO:0098978; GO:0098982; GO:0099072; GO:0099558; GO:0099610; GO:0140059; GO:0150048; GO:1901558; GO:1903598; GO:1904456; GO:1904457; GO:1904861; GO:1904862; GO:1905962; GO:1990403; GO:1990834 11066 FUN_035090 135 178 59 60 32 ptg000025l:3667472-3672910 Q9CPW0 1.05e-68 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Mus musculus (Mouse) action potential initiation [GO:0099610]; adult behavior [GO:0030534]; associative learning [GO:0008306]; axonogenesis [GO:0007409]; behavioral response to pain [GO:0048266]; cell adhesion [GO:0007155]; cell morphogenesis [GO:0000902]; cell population proliferation [GO:0008283]; central nervous system myelination [GO:0022010]; cerebellar Purkinje cell layer morphogenesis [GO:0021692]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; circadian sleep/wake cycle [GO:0042745]; clustering of voltage-gated potassium channels [GO:0045163]; dendrite arborization [GO:0140059]; dendritic spine development [GO:0060996]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; embryonic brain development [GO:1990403]; ERK1 and ERK2 cascade [GO:0070371]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; excitatory synapse assembly [GO:1904861]; fat cell differentiation [GO:0045444]; gene expression [GO:0010467]; glial cell proliferation [GO:0014009]; glutamatergic neuron differentiation [GO:1905962]; grooming behavior [GO:0007625]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; inhibitory chemical synaptic transmission [GO:0098977]; inhibitory synapse assembly [GO:1904862]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; limbic system development [GO:0021761]; locomotor rhythm [GO:0045475]; locomotory behavior [GO:0007626]; maintenance of synapse structure [GO:0099558]; mitochondrion organization [GO:0007005]; motor behavior [GO:0061744]; multicellular organism growth [GO:0035264]; myelination [GO:0042552]; negative regulation of neuronal action potential [GO:1904456]; negative regulation of synaptic transmission, GABAergic [GO:0032229]; neural precursor cell proliferation [GO:0061351]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; neuronal action potential [GO:0019228]; positive regulation of gap junction assembly [GO:1903598]; positive regulation of neuronal action potential [GO:1904457]; postsynaptic density organization [GO:0097106]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; protein localization to juxtaparanode region of axon [GO:0071205]; regulation of postsynaptic membrane neurotransmitter receptor levels [GO:0099072]; response to dietary excess [GO:0002021]; response to heat [GO:0009408]; response to hormone [GO:0009725]; response to interleukin-17 [GO:0097396]; response to light intensity [GO:0009642]; response to mechanical stimulus [GO:0009612]; response to metformin [GO:1901558]; response to odorant [GO:1990834]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; rhythmic behavior [GO:0007622]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625]; walking behavior [GO:0090659] GO:0000902; GO:0001701; GO:0002021; GO:0005769; GO:0005794; GO:0006954; GO:0007005; GO:0007155; GO:0007268; GO:0007409; GO:0007612; GO:0007622; GO:0007625; GO:0007626; GO:0008038; GO:0008076; GO:0008104; GO:0008283; GO:0008306; GO:0009408; GO:0009410; GO:0009612; GO:0009642; GO:0009725; GO:0009986; GO:0010033; GO:0010467; GO:0014009; GO:0016020; GO:0019226; GO:0019228; GO:0019899; GO:0021549; GO:0021692; GO:0021761; GO:0022010; GO:0030165; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0031929; GO:0032229; GO:0033010; GO:0035176; GO:0035264; GO:0035556; GO:0042297; GO:0042552; GO:0042734; GO:0042745; GO:0043005; GO:0043025; GO:0043194; GO:0043491; GO:0044224; GO:0044309; GO:0044853; GO:0045163; GO:0045202; GO:0045444; GO:0045475; GO:0048265; GO:0048266; GO:0048787; GO:0048812; GO:0050884; GO:0050905; GO:0060076; GO:0060079; GO:0060996; GO:0061351; GO:0061744; GO:0070371; GO:0071205; GO:0071625; GO:0090659; GO:0097061; GO:0097062; GO:0097106; GO:0097396; GO:0098529; GO:0098793; GO:0098794; GO:0098976; GO:0098977; GO:0098978; GO:0098982; GO:0099072; GO:0099558; GO:0099610; GO:0140059; GO:0150048; GO:1901558; GO:1903598; GO:1904456; GO:1904457; GO:1904861; GO:1904862; GO:1905962; GO:1990403; GO:1990834 11067 FUN_035097 1425 966 541 0 25 NA NA NA NA NA NA NA 11068 FUN_035096 1048 659 574 399 339 NA NA NA NA NA NA NA 11069 FUN_035095 7268 3285 1098 3250 2509 NA NA NA NA NA NA NA 11070 FUN_035094 7729 5537 5250 7474 6273 NA NA NA NA NA NA NA 11071 FUN_006239 11 10 1 48 54 NA NA NA NA NA NA NA 11072 FUN_006238 1031 1246 1027 909 451 ptg000001l:9631597-9638111 Q9HC07 1.05e-36 Transmembrane protein 165 (Transmembrane protein PT27) (Transmembrane protein TPARL) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; Golgi calcium ion homeostasis [GO:0032468]; Golgi calcium ion transport [GO:0032472]; manganese ion transmembrane transport [GO:0071421]; protein N-linked glycosylation [GO:0006487]; regulation of lysosomal lumen pH [GO:0035751] GO:0000139; GO:0005384; GO:0005765; GO:0005794; GO:0006487; GO:0006874; GO:0010008; GO:0015085; GO:0031901; GO:0031902; GO:0032468; GO:0032472; GO:0032588; GO:0035751; GO:0043231; GO:0046873; GO:0070588; GO:0071421 11073 FUN_042078 0 58 0 0 0 NA NA NA NA NA NA NA 11074 FUN_006230 2025 939 863 1613 1650 ptg000001l:9547701-9559453 Q6NVD0 3.02e-100 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) (NV domain-containing protein 1) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023 11075 FUN_006233 78 23 62 56 109 ptg000001l:9570354-9573807 Q6NVD0 8.75e-173 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) (NV domain-containing protein 1) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023 11076 FUN_006233 78 23 62 56 109 ptg000001l:9570354-9573807 Q6NVD0 1.84e-33 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) (NV domain-containing protein 1) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023 11077 FUN_042070 0 144 0 0 0 NA NA NA NA NA NA NA 11078 FUN_006237 7290 11296 3474 8245 7311 NA NA NA NA NA NA NA 11079 FUN_006236 11862 8229 6180 9731 10307 NA NA NA NA NA NA NA 11080 FUN_040509 49 0 4 44 18 NA NA NA NA NA NA NA 11081 FUN_040508 220 181 37 67 79 ptg000031l:9580394-9593380 Q5DU56 6.19e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11082 FUN_040508 220 181 37 67 79 ptg000031l:9580394-9593380 Q5DU56 3.67e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11083 FUN_040508 220 181 37 67 79 ptg000031l:9580394-9593380 Q5DU56 3.89e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11084 FUN_040507 0 0 0 0 176 NA NA NA NA NA NA NA 11085 FUN_040506 0 0 0 0 149 NA NA NA NA NA NA NA 11086 FUN_040500 178 79 21 45 81 ptg000031l:9431472-9488015 Q5DU56 1.14e-29 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11087 FUN_040500 178 79 21 45 81 ptg000031l:9431472-9488015 Q5DU56 1.34e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11088 FUN_040500 178 79 21 45 81 ptg000031l:9431472-9488015 Q5DU56 1.35e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11089 FUN_040500 178 79 21 45 81 ptg000031l:9431472-9488015 Q5DU56 2.59e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11090 FUN_040500 178 79 21 45 81 ptg000031l:9431472-9488015 Q5DU56 7.02e-24 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11091 FUN_040500 178 79 21 45 81 ptg000031l:9431472-9488015 Q5DU56 1.02e-22 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11092 FUN_040502 15 16 0 0 169 ptg000031l:9506034-9512280 Q7RTR2 2.05e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11093 FUN_043282 6385 21 5390 96 52 NA NA NA NA NA NA NA 11094 FUN_036548 0 0 19 0 0 NA NA NA NA NA NA NA 11095 FUN_036541 416 125 220 351 143 NA NA NA NA NA NA NA 11096 FUN_036542 15 0 28 11 0 NA NA NA NA NA NA NA 11097 FUN_036543 20 0 17 17 0 NA NA NA NA NA NA NA 11098 FUN_036544 1329 1229 1191 1599 0 ptg000025l:19536767-19568002 Q09575 2.66e-35 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11099 FUN_036544 1329 1229 1191 1599 0 ptg000025l:19536767-19568002 Q09575 3.83e-22 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 11100 FUN_036545 251 174 223 344 0 NA NA NA NA NA NA NA 11101 FUN_036546 46 9 9 10 20 NA NA NA NA NA NA NA 11102 FUN_036547 0 6 0 0 0 NA NA NA NA NA NA NA 11103 FUN_032041 15 144 68 16 129 ptg000023l:28318060-28328286 B8VIU6 1.56e-36 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11104 FUN_032040 2831 2099 1505 3334 2326 ptg000023l:28304627-28313957 Q6PA06 4.85e-33 Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2) Mus musculus (Mouse) endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260] GO:0003924; GO:0005525; GO:0005783; GO:0007029; GO:0007030; GO:0016020; GO:0042802; GO:0051260; GO:0098826; GO:1990809 11105 FUN_032040 2831 2099 1505 3334 2326 ptg000023l:28304627-28313957 Q6PA06 4.02e-27 Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2) Mus musculus (Mouse) endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network membrane organization [GO:1990809]; Golgi organization [GO:0007030]; protein homooligomerization [GO:0051260] GO:0003924; GO:0005525; GO:0005783; GO:0007029; GO:0007030; GO:0016020; GO:0042802; GO:0051260; GO:0098826; GO:1990809 11106 FUN_032043 928 716 409 593 533 NA NA NA NA NA NA NA 11107 FUN_032042 126 47 24 37 110 ptg000023l:28332496-28335366 B8VIU6 2.95e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11108 FUN_032045 269 362 202 297 298 ptg000023l:28356523-28358407 Q4JL91 9.31e-38 Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase) Danio rerio (Zebrafish) (Brachydanio rerio) determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; inositol phosphate biosynthetic process [GO:0032958]; inositol phosphorylation [GO:0052746]; melanosome transport [GO:0032402] GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005813; GO:0007368; GO:0032402; GO:0032958; GO:0035299; GO:0036064; GO:0052746; GO:0060287 11109 FUN_032044 4 37 8 19 132 NA NA NA NA NA NA NA 11110 FUN_032047 121 55 25 188 137 NA NA NA NA NA NA NA 11111 FUN_032046 527 408 507 810 984 NA NA NA NA NA NA NA 11112 FUN_032049 1847 1037 803 1329 1120 NA NA NA NA NA NA NA 11113 FUN_032048 14811 11143 6973 9657 7890 ptg000023l:28397280-28415136 Q96DM1 9.16e-45 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 11114 FUN_043852 12 0 3 0 11 NA NA NA NA NA NA NA 11115 FUN_043855 5 0 0 0 8 NA NA NA NA NA NA NA 11116 FUN_043858 5 0 0 0 8 NA NA NA NA NA NA NA 11117 FUN_028772 0 0 0 18 0 NA NA NA NA NA NA NA 11118 FUN_000159 2 0 5 0 13 ntLink_4:260158-260921 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11119 FUN_013075 14 0 5 0 8 NA NA NA NA NA NA NA 11120 FUN_028775 20 2 3 0 10 NA NA NA NA NA NA NA 11121 FUN_028776 92 10 2 0 1 NA NA NA NA NA NA NA 11122 FUN_005159 22 5 17 19 3 ntLink_8:31949542-31950535 Q12950 2.91e-28 Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead-related transcription factor 5) (FREAC-5) (Myeloid factor-alpha) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008301; GO:0009653; GO:0030154; GO:0043565 11123 FUN_005158 1384 628 657 871 1683 NA NA NA NA NA NA NA 11124 FUN_011286 227 170 223 106 334 ptg000007l:8619102-8621727 Q54KA7 5.2e-23 Ankyrin repeat, PH and SEC7 domain containing protein secG Dictyostelium discoideum (Social amoeba) actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005764; GO:0005829; GO:0006935; GO:0030036; GO:0031154; GO:0031589; GO:0032012; GO:0043327 11125 FUN_041758 2891 2373 1168 2058 1448 ptg000035l:7186039-7191284 P18516 9.3e-25 Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3) (Retinoic acid receptor delta) (RAR-delta) Notophthalmus viridescens (Eastern newt) (Triturus viridescens) retinoic acid receptor signaling pathway [GO:0048384] GO:0004879; GO:0005634; GO:0008270; GO:0043565; GO:0048384 11126 FUN_011280 280 494 239 463 353 NA NA NA NA NA NA NA 11127 FUN_011281 102 94 20 251 41 ptg000007l:8537745-8540213 P12804 1.36e-36 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 11128 FUN_011283 2237 2091 1281 2578 1888 NA NA NA NA NA NA NA 11129 FUN_005151 3727 1491 223 4737 1382 NA NA NA NA NA NA NA 11130 FUN_005150 2326 835 23 2398 274 NA NA NA NA NA NA NA 11131 FUN_005153 4052 1401 172 3936 2540 NA NA NA NA NA NA NA 11132 FUN_041750 1495 1351 816 1210 1341 ptg000035l:7128527-7134383 Q9ESX5 2.96e-37 H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1) Mus musculus (Mouse) box H/ACA RNA 3'-end processing [GO:0000495]; box H/ACA RNA metabolic process [GO:0033979]; enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; rRNA pseudouridine synthesis [GO:0031118]; scaRNA localization to Cajal body [GO:0090666]; snoRNA guided rRNA pseudouridine synthesis [GO:0000454]; snRNA pseudouridine synthesis [GO:0031120]; telomerase RNA stabilization [GO:0090669]; telomere maintenance via telomerase [GO:0007004] GO:0000454; GO:0000455; GO:0000495; GO:0001650; GO:0003720; GO:0003723; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0007004; GO:0008284; GO:0009982; GO:0015030; GO:0031118; GO:0031120; GO:0031429; GO:0032212; GO:0033979; GO:0034513; GO:0051973; GO:0070034; GO:0090661; GO:0090666; GO:0090669; GO:1904851; GO:1904872; GO:1904874; GO:1990481 11133 FUN_041750 1495 1351 816 1210 1341 ptg000035l:7128527-7134383 Q9ESX5 2.96e-37 H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1) Mus musculus (Mouse) box H/ACA RNA 3'-end processing [GO:0000495]; box H/ACA RNA metabolic process [GO:0033979]; enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; mRNA pseudouridine synthesis [GO:1990481]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; rRNA pseudouridine synthesis [GO:0031118]; scaRNA localization to Cajal body [GO:0090666]; snoRNA guided rRNA pseudouridine synthesis [GO:0000454]; snRNA pseudouridine synthesis [GO:0031120]; telomerase RNA stabilization [GO:0090669]; telomere maintenance via telomerase [GO:0007004] GO:0000454; GO:0000455; GO:0000495; GO:0001650; GO:0003720; GO:0003723; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0007004; GO:0008284; GO:0009982; GO:0015030; GO:0031118; GO:0031120; GO:0031429; GO:0032212; GO:0033979; GO:0034513; GO:0051973; GO:0070034; GO:0090661; GO:0090666; GO:0090669; GO:1904851; GO:1904872; GO:1904874; GO:1990481 11134 FUN_041757 232 310 116 215 169 NA NA NA NA NA NA NA 11135 FUN_005157 701 618 289 858 651 NA NA NA NA NA NA NA 11136 FUN_000300 158 70 49 171 209 NA NA NA NA NA NA NA 11137 FUN_033398 4 0 2 0 6 NA NA NA NA NA NA NA 11138 FUN_008683 18 0 24 0 0 NA NA NA NA NA NA NA 11139 FUN_008681 17 12 6 0 21 NA NA NA NA NA NA NA 11140 FUN_008686 22 0 0 0 0 NA NA NA NA NA NA NA 11141 FUN_008687 19 52 25 192 66 NA NA NA NA NA NA NA 11142 FUN_008684 0 0 28 0 0 NA NA NA NA NA NA NA 11143 FUN_008685 99 19 9 0 47 NA NA NA NA NA NA NA 11144 FUN_008688 0 0 21 55 152 NA NA NA NA NA NA NA 11145 FUN_008689 0 0 0 14 0 NA NA NA NA NA NA NA 11146 FUN_016883 7 0 0 0 130 NA NA NA NA NA NA NA 11147 FUN_016882 0 0 0 0 591 NA NA NA NA NA NA NA 11148 FUN_016881 0 0 0 0 14 NA NA NA NA NA NA NA 11149 FUN_016887 1747 544 1695 1065 301 NA NA NA NA NA NA NA 11150 FUN_016886 136 37 0 40 73 NA NA NA NA NA NA NA 11151 FUN_033020 626 211 542 612 441 NA NA NA NA NA NA NA 11152 FUN_033021 1893 1153 1238 1920 1240 NA NA NA NA NA NA NA 11153 FUN_033022 1678 1287 693 2020 1029 ptg000023l:38992158-39002764 P97698 5.05e-25 Smoothened homolog (SMO) Rattus norvegicus (Rat) alpha-tubulin acetylation [GO:0071929]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; astrocyte activation [GO:0048143]; atrial septum morphogenesis [GO:0060413]; axon extension involved in axon guidance [GO:0048846]; cell development [GO:0048468]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to cholesterol [GO:0071397]; central nervous system development [GO:0007417]; central nervous system neuron differentiation [GO:0021953]; cerebellar cortex morphogenesis [GO:0021696]; cerebral cortex development [GO:0021987]; commissural neuron axon guidance [GO:0071679]; contact inhibition [GO:0060242]; dentate gyrus development [GO:0021542]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; developmental growth [GO:0048589]; digestive tract development [GO:0048565]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; dorsal/ventral pattern formation [GO:0009953]; embryonic organ development [GO:0048568]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; epithelial-mesenchymal cell signaling [GO:0060684]; facial nerve development [GO:0021561]; forebrain morphogenesis [GO:0048853]; hair follicle development [GO:0001942]; hair follicle morphogenesis [GO:0031069]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; homeostasis of number of cells within a tissue [GO:0048873]; in utero embryonic development [GO:0001701]; left/right axis specification [GO:0070986]; mammary gland epithelial cell differentiation [GO:0060644]; mesenchymal to epithelial transition [GO:0060231]; mesenchymal to epithelial transition involved in metanephric renal vesicle formation [GO:0072285]; midgut development [GO:0007494]; multicellular organism growth [GO:0035264]; myoblast migration [GO:0051451]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell differentiation [GO:0030857]; negative regulation of gene expression [GO:0010629]; negative regulation of hair follicle development [GO:0051799]; negative regulation of hepatocyte proliferation [GO:2000346]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neuron death [GO:1901215]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neuroblast proliferation [GO:0007405]; neuron projection regeneration [GO:0031102]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; pancreas morphogenesis [GO:0061113]; pattern specification process [GO:0007389]; positive regulation of autophagy [GO:0010508]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of hh target transcription factor activity [GO:0007228]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of organ growth [GO:0046622]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein import into nucleus [GO:0006606]; protein localization to nucleus [GO:0034504]; protein stabilization [GO:0050821]; regulation of gene expression [GO:0010468]; regulation of heart morphogenesis [GO:2000826]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of stem cell population maintenance [GO:2000036]; response to organic substance [GO:0010033]; response to wounding [GO:0009611]; skeletal muscle fiber development [GO:0048741]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation [GO:0021938]; smoothened signaling pathway involved in ventral spinal cord patterning [GO:0021910]; somite development [GO:0061053]; spermatogenesis [GO:0007283]; thalamus development [GO:0021794]; type B pancreatic cell development [GO:0003323]; vasculogenesis [GO:0001570]; ventral midline determination [GO:0007371] GO:0000122; GO:0001503; GO:0001570; GO:0001649; GO:0001701; GO:0001708; GO:0001755; GO:0001942; GO:0001947; GO:0002052; GO:0002053; GO:0003007; GO:0003140; GO:0003323; GO:0004930; GO:0005113; GO:0005634; GO:0005737; GO:0005814; GO:0005886; GO:0005929; GO:0006606; GO:0006915; GO:0007224; GO:0007228; GO:0007283; GO:0007368; GO:0007371; GO:0007389; GO:0007405; GO:0007417; GO:0007494; GO:0008283; GO:0008284; GO:0009611; GO:0009952; GO:0009953; GO:0010033; GO:0010468; GO:0010508; GO:0010628; GO:0010629; GO:0014069; GO:0016020; GO:0021542; GO:0021561; GO:0021696; GO:0021794; GO:0021904; GO:0021910; GO:0021938; GO:0021953; GO:0021987; GO:0030335; GO:0030425; GO:0030855; GO:0030857; GO:0031069; GO:0031102; GO:0033687; GO:0034504; GO:0035264; GO:0040018; GO:0042307; GO:0042475; GO:0043025; GO:0043066; GO:0043231; GO:0043392; GO:0043524; GO:0044294; GO:0044295; GO:0045880; GO:0045892; GO:0045893; GO:0045944; GO:0046622; GO:0048143; GO:0048468; GO:0048565; GO:0048568; GO:0048589; GO:0048741; GO:0048745; GO:0048846; GO:0048853; GO:0048873; GO:0050673; GO:0050679; GO:0050821; GO:0051451; GO:0051799; GO:0060170; GO:0060231; GO:0060242; GO:0060413; GO:0060644; GO:0060684; GO:0061053; GO:0061113; GO:0070986; GO:0071397; GO:0071542; GO:0071679; GO:0071929; GO:0072285; GO:0090190; GO:0097731; GO:1901215; GO:1904672; GO:1904754; GO:2000036; GO:2000179; GO:2000346; GO:2000491; GO:2000826 11154 FUN_033023 207 80 56 174 211 ptg000023l:39004736-39006782 Q4R7I0 7.08e-26 Centrosomal protein of 44 kDa (Cep44) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) centriole replication [GO:0007099]; centriole-centriole cohesion [GO:0010457]; centrosome cycle [GO:0007098] GO:0000922; GO:0005737; GO:0005813; GO:0005814; GO:0007098; GO:0007099; GO:0008017; GO:0010457; GO:0030496 11155 FUN_033024 486 300 338 452 420 NA NA NA NA NA NA NA 11156 FUN_033025 1989 1411 574 1182 1096 NA NA NA NA NA NA NA 11157 FUN_033026 0 0 6 9 0 NA NA NA NA NA NA NA 11158 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 3.76e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11159 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 2.2e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11160 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 2.51e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11161 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 3.06e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11162 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 1.77e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11163 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 5.35e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11164 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 8.11e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11165 FUN_033027 24 22 111 79 0 ptg000023l:39026175-39030882 Q96AY4 3.28e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11166 FUN_028987 1859 1918 1130 1935 1589 NA NA NA NA NA NA NA 11167 FUN_028986 280 182 72 473 150 NA NA NA NA NA NA NA 11168 FUN_028985 4705 2552 1560 4306 2245 NA NA NA NA NA NA NA 11169 FUN_028984 3076 3371 1638 2220 1445 NA NA NA NA NA NA NA 11170 FUN_028983 5324 5167 1963 3680 3970 ptg000022l:6770869-6776690 Q99JI4 6.14e-32 26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (p42A) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005838; GO:0022624; GO:0043161 11171 FUN_028982 1051 1492 501 1149 722 NA NA NA NA NA NA NA 11172 FUN_028981 1186 516 537 654 1000 NA NA NA NA NA NA NA 11173 FUN_028980 2823 3042 1202 2597 2286 NA NA NA NA NA NA NA 11174 FUN_028989 1236 673 543 984 585 ptg000022l:6852372-6863603 B8VIU6 1.24e-46 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11175 FUN_028989 1236 673 543 984 585 ptg000022l:6852372-6863603 B8VIU6 2.78e-44 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11176 FUN_028988 893 379 381 735 362 ptg000022l:6819270-6846681 B8VIU6 1.51e-51 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11177 FUN_028988 893 379 381 735 362 ptg000022l:6819270-6846681 B8VIU6 8.53e-51 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11178 FUN_028988 893 379 381 735 362 ptg000022l:6819270-6846681 B8VIU6 6.52e-49 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11179 FUN_028988 893 379 381 735 362 ptg000022l:6819270-6846681 B8VIU6 1.88e-42 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11180 FUN_028988 893 379 381 735 362 ptg000022l:6819270-6846681 B8VIU6 3.47e-23 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 11181 FUN_029765 225 111 104 365 124 NA NA NA NA NA NA NA 11182 FUN_016775 381 232 340 69 116 NA NA NA NA NA NA NA 11183 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 1.28e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11184 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 9.58e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11185 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 1.26e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11186 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 1.78e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11187 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 1.13e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11188 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 1.6e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11189 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 4.13e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11190 FUN_016774 58 141 60 20 65 ptg000011l:7328017-7331790 Q96AY4 3.13e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11191 FUN_016777 1899 1608 1461 2228 1541 ptg000011l:7365050-7376685 Q6P9S7 9.72e-27 Polypeptide N-acetylgalactosaminyltransferase 10 (EC 2.4.1.41) (Polypeptide GalNAc transferase 10) (GalNAc-T10) (pp-GaNTase 10) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10) Mus musculus (Mouse) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0016266; GO:0030246; GO:0046872 11192 FUN_016777 1899 1608 1461 2228 1541 ptg000011l:7365050-7376685 Q6P9S7 1.13e-24 Polypeptide N-acetylgalactosaminyltransferase 10 (EC 2.4.1.41) (Polypeptide GalNAc transferase 10) (GalNAc-T10) (pp-GaNTase 10) (Protein-UDP acetylgalactosaminyltransferase 10) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10) Mus musculus (Mouse) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0016266; GO:0030246; GO:0046872 11193 FUN_028161 4394 1210 2902 711 764 NA NA NA NA NA NA NA 11194 FUN_016770 38 6 0 58 7 ptg000011l:7263148-7269996 Q96AY4 5.79e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11195 FUN_016770 38 6 0 58 7 ptg000011l:7263148-7269996 Q96AY4 1.22e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11196 FUN_016770 38 6 0 58 7 ptg000011l:7263148-7269996 Q96AY4 4.05e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11197 FUN_016770 38 6 0 58 7 ptg000011l:7263148-7269996 Q96AY4 5.06e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11198 FUN_016770 38 6 0 58 7 ptg000011l:7263148-7269996 Q96AY4 1.01e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11199 FUN_016770 38 6 0 58 7 ptg000011l:7263148-7269996 Q96AY4 5.4e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11200 FUN_016773 697 16 1122 67 19 NA NA NA NA NA NA NA 11201 FUN_042812 20 0 0 5 0 NA NA NA NA NA NA NA 11202 FUN_003654 0 14 36 5 128 NA NA NA NA NA NA NA 11203 FUN_040082 143 256 73 232 201 ptg000031l:3974125-3979600 Q8CGQ8 3.2e-30 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Mus musculus (Mouse) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005432; GO:0005516; GO:0005737; GO:0005886; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 11204 FUN_040082 143 256 73 232 201 ptg000031l:3974125-3979600 Q8CGQ8 1.08e-24 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Mus musculus (Mouse) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005432; GO:0005516; GO:0005737; GO:0005886; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 11205 FUN_040083 77 67 32 2 10 NA NA NA NA NA NA NA 11206 FUN_040084 43 71 0 157 41 NA NA NA NA NA NA NA 11207 FUN_040085 695 508 365 557 436 NA NA NA NA NA NA NA 11208 FUN_040086 362 193 562 570 818 NA NA NA NA NA NA NA 11209 FUN_040087 517 520 125 681 355 NA NA NA NA NA NA NA 11210 FUN_012252 1625 1370 1123 2015 1915 ptg000008l:6825562-6842891 Q7LHG5 5.52e-73 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 11211 FUN_012253 2 0 0 44 82 NA NA NA NA NA NA NA 11212 FUN_012250 3898 2615 1836 3197 2649 NA NA NA NA NA NA NA 11213 FUN_012251 1953 1916 1124 2925 2011 NA NA NA NA NA NA NA 11214 FUN_012256 502 639 401 492 549 NA NA NA NA NA NA NA 11215 FUN_012257 2699 1261 810 1199 1484 NA NA NA NA NA NA NA 11216 FUN_012254 521 173 202 388 142 NA NA NA NA NA NA NA 11217 FUN_012255 224 419 297 139 160 NA NA NA NA NA NA NA 11218 FUN_012258 210 195 75 245 310 NA NA NA NA NA NA NA 11219 FUN_012259 262 242 227 541 686 NA NA NA NA NA NA NA 11220 FUN_028363 10 16 10 10 3 NA NA NA NA NA NA NA 11221 FUN_028362 94 173 139 645 89 NA NA NA NA NA NA NA 11222 FUN_028361 0 0 0 475 0 NA NA NA NA NA NA NA 11223 FUN_028360 0 0 0 696 77 NA NA NA NA NA NA NA 11224 FUN_028367 0 12 4 93 0 NA NA NA NA NA NA NA 11225 FUN_028366 73 150 306 622 37 NA NA NA NA NA NA NA 11226 FUN_028365 1013 703 401 2119 216 NA NA NA NA NA NA NA 11227 FUN_028364 0 19 0 59 0 NA NA NA NA NA NA NA 11228 FUN_028369 247 291 399 685 657 NA NA NA NA NA NA NA 11229 FUN_028368 0 0 0 0 18 NA NA NA NA NA NA NA 11230 FUN_042626 602 596 906 256 376 NA NA NA NA NA NA NA 11231 FUN_003888 0 32 30 65 0 NA NA NA NA NA NA NA 11232 FUN_043008 9177 13191 7457 9119 4096 ptg000047l:2921097-2929245 Q5R6Q2 3.3e-35 Syntaxin-6 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endocytic recycling [GO:0032456]; endosome organization [GO:0007032]; Golgi vesicle transport [GO:0048193]; intracellular protein transport [GO:0006886]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147]; vesicle fusion [GO:0006906] GO:0000139; GO:0005484; GO:0005654; GO:0005769; GO:0005829; GO:0006886; GO:0006906; GO:0007032; GO:0019905; GO:0031201; GO:0032456; GO:0032588; GO:0032880; GO:0042147; GO:0045335; GO:0048193; GO:0048471; GO:0055037; GO:0055038 11233 FUN_030061 390 768 212 611 751 ptg000023l:8908286-8911061 Q4UMH6 4.51e-42 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 11234 FUN_030061 390 768 212 611 751 ptg000023l:8908286-8911061 Q4UMH6 2.09e-31 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 11235 FUN_030061 390 768 212 611 751 ptg000023l:8908286-8911061 Q4UMH6 5.29e-31 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 11236 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 1.53e-66 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11237 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 1.44e-53 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11238 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 1.35e-49 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11239 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 1.49e-49 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11240 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 1.92e-44 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11241 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 2.84e-42 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11242 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 2.79e-41 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11243 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 8.07e-38 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11244 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 9.42e-27 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11245 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 2.71e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11246 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 2.86e-21 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11247 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 3.32e-21 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11248 FUN_030063 783 89 691 1061 341 ptg000023l:8978391-9007674 P98133 3.93e-21 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 11249 FUN_019427 0 0 0 0 25 NA NA NA NA NA NA NA 11250 FUN_023143 278 30 138 396 382 NA NA NA NA NA NA NA 11251 FUN_019420 7 132 112 74 135 NA NA NA NA NA NA NA 11252 FUN_019422 6 79 115 76 128 NA NA NA NA NA NA NA 11253 FUN_003887 3975 2868 2499 3755 2945 ntLink_8:16512679-16526038 Q8MJ44 3.53e-23 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Canis lupus familiaris (Dog) (Canis familiaris) cellular response to heat [GO:0034605]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468] GO:0001669; GO:0004674; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0006468; GO:0010737; GO:0034237; GO:0034605; GO:0036126; GO:0048471; GO:0106310 11254 FUN_042629 244 139 479 171 246 ptg000039l:543053-544487 Q98TB4 1.2e-28 Growth/differentiation factor 8 (Myostatin) (MSTN) Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) NA GO:0005125; GO:0005615; GO:0008083 11255 FUN_043062 0 0 0 0 16 NA NA NA NA NA NA NA 11256 FUN_043061 59 26 25 72 162 ptg000047l:3579914-3587520 Q96AY4 5.55e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11257 FUN_043061 59 26 25 72 162 ptg000047l:3579914-3587520 Q96AY4 2.4e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11258 FUN_043061 59 26 25 72 162 ptg000047l:3579914-3587520 Q96AY4 7.92e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11259 FUN_043061 59 26 25 72 162 ptg000047l:3579914-3587520 Q96AY4 2.13e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11260 FUN_043061 59 26 25 72 162 ptg000047l:3579914-3587520 Q96AY4 3.88e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11261 FUN_043061 59 26 25 72 162 ptg000047l:3579914-3587520 Q96AY4 4.55e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11262 FUN_011500 0 0 0 0 18 NA NA NA NA NA NA NA 11263 FUN_011507 0 0 0 0 7 NA NA NA NA NA NA NA 11264 FUN_011506 0 0 8 0 0 NA NA NA NA NA NA NA 11265 FUN_043065 104 68 53 157 184 ptg000047l:3615739-3622134 Q96AY4 6.05e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11266 FUN_043065 104 68 53 157 184 ptg000047l:3615739-3622134 Q96AY4 2.73e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11267 FUN_043065 104 68 53 157 184 ptg000047l:3615739-3622134 Q96AY4 6.81e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11268 FUN_043065 104 68 53 157 184 ptg000047l:3615739-3622134 Q96AY4 1.04e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11269 FUN_043065 104 68 53 157 184 ptg000047l:3615739-3622134 Q96AY4 6.3e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11270 FUN_043065 104 68 53 157 184 ptg000047l:3615739-3622134 Q96AY4 5.73e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11271 FUN_043069 25 0 21 16 218 NA NA NA NA NA NA NA 11272 FUN_013615 5390 3010 2938 4840 3966 NA NA NA NA NA NA NA 11273 FUN_013614 0 2 11 13 78 NA NA NA NA NA NA NA 11274 FUN_013617 496 834 439 434 456 NA NA NA NA NA NA NA 11275 FUN_013616 353 160 370 259 702 NA NA NA NA NA NA NA 11276 FUN_013611 951 659 490 1291 440 ptg000008l:24498966-24500142 Q8NFJ9 4.52e-171 Bardet-Biedl syndrome 1 protein (BBS2-like protein 2) Homo sapiens (Human) adult behavior [GO:0030534]; brain morphogenesis [GO:0048854]; cartilage development [GO:0051216]; cellular lipid metabolic process [GO:0044255]; cerebral cortex development [GO:0021987]; cilium assembly [GO:0060271]; dendrite development [GO:0016358]; fat cell differentiation [GO:0045444]; fertilization [GO:0009566]; Golgi to plasma membrane protein transport [GO:0043001]; hippocampus development [GO:0021766]; hormone metabolic process [GO:0042445]; microtubule cytoskeleton organization [GO:0000226]; neural precursor cell proliferation [GO:0061351]; neuron migration [GO:0001764]; non-motile cilium assembly [GO:1905515]; olfactory behavior [GO:0042048]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell morphogenesis [GO:0008594]; protein localization to cilium [GO:0061512]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296]; sensory perception of smell [GO:0007608]; striatum development [GO:0021756]; ventricular system development [GO:0021591]; visual perception [GO:0007601] GO:0000226; GO:0001764; GO:0005113; GO:0005119; GO:0005813; GO:0005829; GO:0005930; GO:0007601; GO:0007608; GO:0008594; GO:0009566; GO:0016358; GO:0021591; GO:0021756; GO:0021766; GO:0021987; GO:0030534; GO:0031514; GO:0034451; GO:0034464; GO:0042048; GO:0042445; GO:0043001; GO:0044255; GO:0045444; GO:0045494; GO:0048854; GO:0051216; GO:0051219; GO:0060170; GO:0060271; GO:0060296; GO:0061351; GO:0061512; GO:0061629; GO:1905515 11277 FUN_013610 1201 915 534 629 739 ptg000008l:24476657-24479596 Q9D7M8 5.66e-24 DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) Mus musculus (Mouse) mRNA export from nucleus in response to heat stress [GO:0031990]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of translational initiation [GO:0045948]; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [GO:0034402]; transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000166; GO:0000288; GO:0000932; GO:0005634; GO:0005654; GO:0005665; GO:0005829; GO:0006366; GO:0006367; GO:0016607; GO:0031369; GO:0031990; GO:0034402; GO:0045948 11278 FUN_013613 13950 8730 8620 12978 9492 ptg000008l:24507296-24520403 Q9P2K9 1.15e-22 Protein dispatched homolog 3 (Patched domain-containing protein 2) Homo sapiens (Human) cell differentiation [GO:0030154]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of lipid metabolic process [GO:0045834]; positive regulation of neural precursor cell proliferation [GO:2000179]; regulation of lipid transport [GO:0032368]; smoothened signaling pathway [GO:0007224] GO:0005737; GO:0005783; GO:0005789; GO:0007224; GO:0008203; GO:0016020; GO:0030154; GO:0030659; GO:0031965; GO:0032368; GO:0042632; GO:0045665; GO:0045834; GO:2000179 11279 FUN_013612 240 358 293 826 440 ptg000008l:24501567-24504861 Q5TDH0 1.41e-97 Protein DDI1 homolog 2 (EC 3.4.23.-) Homo sapiens (Human) cellular response to hydroxyurea [GO:0072711]; proteasomal protein catabolic process [GO:0010498]; protein processing [GO:0016485]; regulation of DNA stability [GO:0097752]; regulation of protein stability [GO:0031647] GO:0004190; GO:0005654; GO:0005694; GO:0005829; GO:0010498; GO:0016485; GO:0031647; GO:0042802; GO:0043130; GO:0072711; GO:0097752 11280 FUN_013619 200 129 206 342 306 NA NA NA NA NA NA NA 11281 FUN_013618 23 134 15 34 78 ptg000008l:24579674-24581913 Q9WUU9 4.14e-49 Germinal-center associated nuclear protein (GANP) (EC 2.3.1.48) (GC-associated DNA primase) Mus musculus (Mouse) mRNA export from nucleus [GO:0006406]; nucleosome organization [GO:0034728]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003676; GO:0003682; GO:0004402; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0006406; GO:0010484; GO:0015031; GO:0016446; GO:0016973; GO:0031965; GO:0034728; GO:0042393; GO:0044615; GO:0070390 11282 FUN_009652 1003 932 541 703 598 ptg000004l:9973356-9983817 Q5ZLK1 7.34e-43 DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) Gallus gallus (Chicken) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; protein ubiquitination [GO:0016567] GO:0000462; GO:0005730; GO:0016567; GO:0032040; GO:0080008 11283 FUN_009652 1003 932 541 703 598 ptg000004l:9973356-9983817 Q5ZLK1 2.76e-35 DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) Gallus gallus (Chicken) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; protein ubiquitination [GO:0016567] GO:0000462; GO:0005730; GO:0016567; GO:0032040; GO:0080008 11284 FUN_009653 4152 4747 2805 3219 2100 NA NA NA NA NA NA NA 11285 FUN_009650 0 32 0 79 4 ptg000004l:9960852-9965525 O62714 5.51e-43 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) Sus scrofa (Pig) cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of calcium ion transport [GO:0051924] GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006874; GO:0007186; GO:0016597; GO:0042803; GO:0051924 11286 FUN_009656 12955 11079 6580 10634 7438 ptg000004l:10021768-10028643 P41932 7.78e-32 14-3-3-like protein 1 (Partitioning defective protein 5) Caenorhabditis elegans asymmetric protein localization involved in cell fate determination [GO:0045167]; cell fate specification [GO:0001708]; cytoplasmic sequestering of transcription factor [GO:0042994]; determination of adult lifespan [GO:0008340]; embryo development ending in birth or egg hatching [GO:0009792]; establishment of mitotic spindle orientation [GO:0000132]; first cell cycle pseudocleavage [GO:0030590]; heat acclimation [GO:0010286]; maintenance of protein location in nucleus [GO:0051457]; meiotic cell cycle [GO:0051321]; negative regulation of gene expression [GO:0010629]; polarity specification of anterior/posterior axis [GO:0009949]; pronuclear migration [GO:0035046]; protein export from nucleus [GO:0006611]; regulation of gene expression [GO:0010468]; regulation of mitotic cell cycle [GO:0007346]; reproduction [GO:0000003]; signal transduction [GO:0007165]; zygote asymmetric cell division [GO:0010070] GO:0000003; GO:0000132; GO:0001708; GO:0005634; GO:0005737; GO:0005938; GO:0006611; GO:0007165; GO:0007346; GO:0008340; GO:0009792; GO:0009949; GO:0010070; GO:0010286; GO:0010468; GO:0010629; GO:0030590; GO:0035046; GO:0042994; GO:0045167; GO:0051321; GO:0051457 11287 FUN_009657 527 535 134 338 377 NA NA NA NA NA NA NA 11288 FUN_009654 3375 2185 834 2476 1634 NA NA NA NA NA NA NA 11289 FUN_009655 2 42 2 0 18 NA NA NA NA NA NA NA 11290 FUN_029579 9 16 7 10 8 NA NA NA NA NA NA NA 11291 FUN_029578 632 216 191 143 178 ptg000023l:3478671-3486624 E7FAM5 1.42e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 11292 FUN_029578 632 216 191 143 178 ptg000023l:3478671-3486624 E7FAM5 4.48e-51 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 11293 FUN_029571 144 71 25 30 125 NA NA NA NA NA NA NA 11294 FUN_029570 2219 1047 945 1500 1259 NA NA NA NA NA NA NA 11295 FUN_029573 164 592 363 522 273 NA NA NA NA NA NA NA 11296 FUN_029572 601 0 283 299 192 NA NA NA NA NA NA NA 11297 FUN_029575 1137 392 275 345 185 ptg000023l:3470486-3472703 E7FAM5 8.87e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 11298 FUN_029574 117 66 151 86 73 ptg000023l:3462650-3466011 E7FAM5 4.18e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 11299 FUN_029577 81 31 42 17 31 NA NA NA NA NA NA NA 11300 FUN_029576 77 20 9 8 22 NA NA NA NA NA NA NA 11301 FUN_026242 1062 485 763 66 899 ptg000020l:6660284-6680489 P16157 1.36e-56 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11302 FUN_026242 1062 485 763 66 899 ptg000020l:6660284-6680489 P16157 7.58e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11303 FUN_026242 1062 485 763 66 899 ptg000020l:6660284-6680489 P16157 7.64e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11304 FUN_026242 1062 485 763 66 899 ptg000020l:6660284-6680489 P16157 5.66e-34 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11305 FUN_026242 1062 485 763 66 899 ptg000020l:6660284-6680489 P16157 9.33e-23 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11306 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 4.21e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11307 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 4.21e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11308 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 1.45e-39 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11309 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 1.45e-39 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11310 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 2.19e-37 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11311 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 1.46e-32 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11312 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 6.23e-30 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11313 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 8.37e-30 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11314 FUN_026240 723 1589 342 0 363 ptg000020l:6597154-6609975 P16157 2.91e-24 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11315 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 2.18e-71 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11316 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 1.09e-67 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11317 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 7.14e-63 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11318 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 2.38e-56 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11319 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 5.4e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11320 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 1.1e-49 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11321 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 5.6e-43 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11322 FUN_026241 510 167 240 203 133 ptg000020l:6622863-6639781 P16157 3.4e-22 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11323 FUN_026247 0 10 0 0 11 NA NA NA NA NA NA NA 11324 FUN_026244 0 0 56 72 9 NA NA NA NA NA NA NA 11325 FUN_026245 404 28 201 289 98 ptg000020l:6714793-6719686 P16157 2.22e-93 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11326 FUN_026245 404 28 201 289 98 ptg000020l:6714793-6719686 P16157 8.41e-75 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11327 FUN_026245 404 28 201 289 98 ptg000020l:6714793-6719686 P16157 9.52e-65 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11328 FUN_026245 404 28 201 289 98 ptg000020l:6714793-6719686 P16157 3.05e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 11329 FUN_026248 8 956 0 0 0 NA NA NA NA NA NA NA 11330 FUN_009302 89 95 128 147 139 NA NA NA NA NA NA NA 11331 FUN_002131 0 0 13 0 0 NA NA NA NA NA NA NA 11332 FUN_009304 2207 1332 1024 1510 1017 ptg000004l:5132724-5137584 Q99JT9 8.96e-26 Acireductone dioxygenase (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD') (Fe-ARD) (EC 1.13.11.54) (Acireductone dioxygenase (Ni(2+)-requiring)) (ARD) (Ni-ARD) (EC 1.13.11.53) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1) Mus musculus (Mouse) L-methionine salvage from methylthioadenosine [GO:0019509]; methionine metabolic process [GO:0006555] GO:0005506; GO:0005634; GO:0005737; GO:0005886; GO:0006555; GO:0010308; GO:0010309; GO:0016151; GO:0016491; GO:0019509 11333 FUN_009305 0 0 18 0 0 NA NA NA NA NA NA NA 11334 FUN_025917 948 689 411 768 770 NA NA NA NA NA NA NA 11335 FUN_025916 0 5 18 17 2 NA NA NA NA NA NA NA 11336 FUN_025915 1154 1309 458 870 1243 NA NA NA NA NA NA NA 11337 FUN_025914 4033 3554 1500 4050 3082 NA NA NA NA NA NA NA 11338 FUN_025913 704 693 437 1165 518 NA NA NA NA NA NA NA 11339 FUN_002134 0 0 0 0 8 NA NA NA NA NA NA NA 11340 FUN_025911 4377 2605 2967 3831 4323 NA NA NA NA NA NA NA 11341 FUN_025910 149 26 32 117 146 ptg000020l:1860387-1869394 A0A0R4ITC5 4.36e-26 Transformation/transcription domain-associated protein Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; neuromast hair cell development [GO:0035675]; regulation of DNA-templated transcription [GO:0006355] GO:0000124; GO:0005634; GO:0006281; GO:0006325; GO:0006355; GO:0035267; GO:0035675 11342 FUN_025910 149 26 32 117 146 ptg000020l:1860387-1869394 A0A0R4ITC5 4.12e-23 Transformation/transcription domain-associated protein Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; DNA repair [GO:0006281]; neuromast hair cell development [GO:0035675]; regulation of DNA-templated transcription [GO:0006355] GO:0000124; GO:0005634; GO:0006281; GO:0006325; GO:0006355; GO:0035267; GO:0035675 11343 FUN_025919 210 960 0 957 54 NA NA NA NA NA NA NA 11344 FUN_025918 101 45 203 14 43 NA NA NA NA NA NA NA 11345 FUN_028043 625 366 231 602 323 NA NA NA NA NA NA NA 11346 FUN_023547 136 0 0 6 4 NA NA NA NA NA NA NA 11347 FUN_023545 0 20 20 64 0 NA NA NA NA NA NA NA 11348 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 2.35e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11349 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 4.05e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11350 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 6.79e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11351 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 7.19e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11352 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 4.03e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11353 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 2.5e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11354 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 3.53e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11355 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 2.93e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11356 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 1.81e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11357 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 5.03e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11358 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 1.41e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11359 FUN_023542 64 8 25 26 18 ptg000017l:8913725-8915000 Q96AY4 3.63e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11360 FUN_023549 305 50 104 447 367 ptg000017l:8954191-8959551 Q96RS0 2.98e-95 Trimethylguanosine synthase (EC 2.1.1.-) (CLL-associated antigen KW-2) (Cap-specific guanine-N2 methyltransferase) (Hepatocellular carcinoma-associated antigen 137) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT) Homo sapiens (Human) 7-methylguanosine cap hypermethylation [GO:0036261]; 7-methylguanosine RNA capping [GO:0009452]; ribonucleoprotein complex biogenesis [GO:0022613]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0005615; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0008173; GO:0009452; GO:0015030; GO:0022613; GO:0030532; GO:0036261; GO:0071164 11361 FUN_015519 38 60 13 17 46 NA NA NA NA NA NA NA 11362 FUN_022499 1742 785 538 1152 829 NA NA NA NA NA NA NA 11363 FUN_039894 14 0 0 22 0 ptg000031l:1480616-1482446 P16389 2.12e-72 Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2) Homo sapiens (Human) cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion export across plasma membrane [GO:0097623]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005267; GO:0005789; GO:0005886; GO:0006813; GO:0008076; GO:0014059; GO:0015271; GO:0016020; GO:0019228; GO:0019233; GO:0019894; GO:0021633; GO:0021987; GO:0022038; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045188; GO:0045211; GO:0051260; GO:0071805; GO:0097623; GO:0098978; GO:0099508; GO:1905030 11364 FUN_039893 2145 1440 1005 1662 1224 ptg000031l:1464649-1478925 Q802W2 1.17e-33 4-trimethylaminobutyraldehyde dehydrogenase B (TMABA-DH) (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1-B) (EC 1.2.1.3) Danio rerio (Zebrafish) (Brachydanio rerio) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; protein homotetramerization [GO:0051289] GO:0004029; GO:0005829; GO:0006081; GO:0019145; GO:0043878; GO:0045329; GO:0047105; GO:0051289 11365 FUN_039893 2145 1440 1005 1662 1224 ptg000031l:1464649-1478925 Q802W2 3.96e-24 4-trimethylaminobutyraldehyde dehydrogenase B (TMABA-DH) (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1-B) (EC 1.2.1.3) Danio rerio (Zebrafish) (Brachydanio rerio) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; protein homotetramerization [GO:0051289] GO:0004029; GO:0005829; GO:0006081; GO:0019145; GO:0043878; GO:0045329; GO:0047105; GO:0051289 11366 FUN_039893 2145 1440 1005 1662 1224 ptg000031l:1464649-1478925 Q802W2 2.23e-22 4-trimethylaminobutyraldehyde dehydrogenase B (TMABA-DH) (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase family 9 member A1-B) (EC 1.2.1.3) Danio rerio (Zebrafish) (Brachydanio rerio) carnitine biosynthetic process [GO:0045329]; cellular aldehyde metabolic process [GO:0006081]; protein homotetramerization [GO:0051289] GO:0004029; GO:0005829; GO:0006081; GO:0019145; GO:0043878; GO:0045329; GO:0047105; GO:0051289 11367 FUN_039892 2005 1649 908 3108 1186 NA NA NA NA NA NA NA 11368 FUN_039891 0 44 0 21 19 NA NA NA NA NA NA NA 11369 FUN_039890 0 17 0 61 17 NA NA NA NA NA NA NA 11370 FUN_022492 0 70 0 230 20 NA NA NA NA NA NA NA 11371 FUN_022491 87 33 65 45 62 ptg000016l:9574588-9578109 Q07998 6.49e-40 T-box transcription factor T-A (Brachyury protein homolog-A) (No tail protein A-A) (No tail protein-A) (Protein T homolog-A) (T-box protein ZfT-A) (Zf-T-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell fate specification [GO:0001708]; convergent extension involved in axis elongation [GO:0060028]; convergent extension involved in nephron morphogenesis [GO:0072045]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right asymmetry in diencephalon [GO:0035462]; determination of left/right asymmetry in lateral mesoderm [GO:0003140]; determination of left/right symmetry [GO:0007368]; digestive tract development [GO:0048565]; embryonic heart tube morphogenesis [GO:0003143]; heart looping [GO:0001947]; heart morphogenesis [GO:0003007]; Kupffer's vesicle development [GO:0070121]; liver development [GO:0001889]; mesoderm development [GO:0007498]; mesoderm formation [GO:0001707]; notochord cell differentiation [GO:0060034]; notochord development [GO:0030903]; notochord formation [GO:0014028]; pancreas development [GO:0031016]; positive regulation of DNA-templated transcription [GO:0045893]; post-anal tail morphogenesis [GO:0036342]; pronephric glomerulus morphogenesis [GO:0035775]; regulation of BMP signaling pathway involved in heart jogging [GO:2000223]; regulation of endodermal cell fate specification [GO:0042663]; regulation of transcription by RNA polymerase II [GO:0006357]; somite development [GO:0061053]; somitogenesis [GO:0001756]; specification of animal organ position [GO:0010159]; Wnt signaling pathway [GO:0016055] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001707; GO:0001708; GO:0001756; GO:0001889; GO:0001947; GO:0003007; GO:0003140; GO:0003143; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007498; GO:0010159; GO:0014028; GO:0016055; GO:0030903; GO:0031016; GO:0035462; GO:0035775; GO:0036342; GO:0042663; GO:0043565; GO:0045893; GO:0048565; GO:0060028; GO:0060034; GO:0061053; GO:0061371; GO:0070121; GO:0072045; GO:2000223 11372 FUN_015514 101 36 0 32 85 NA NA NA NA NA NA NA 11373 FUN_022496 40 0 30 10 177 NA NA NA NA NA NA NA 11374 FUN_022494 694 1001 377 453 522 NA NA NA NA NA NA NA 11375 FUN_000311 9 0 7 15 6 NA NA NA NA NA NA NA 11376 FUN_017611 0 0 0 0 12 NA NA NA NA NA NA NA 11377 FUN_018646 0 109 0 0 0 NA NA NA NA NA NA NA 11378 FUN_018645 0 80 0 141 49 NA NA NA NA NA NA NA 11379 FUN_017615 4 0 7 16 0 NA NA NA NA NA NA NA 11380 FUN_017617 0 0 0 0 7 NA NA NA NA NA NA NA 11381 FUN_017618 187 178 18 1 9 NA NA NA NA NA NA NA 11382 FUN_018648 0 0 0 19 39 NA NA NA NA NA NA NA 11383 FUN_000582 49 54 25 18 6 NA NA NA NA NA NA NA 11384 FUN_014746 0 11 31 21 40 ptg000009l:2698175-2699315 P97292 1.74e-28 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 11385 FUN_000585 611 386 180 421 473 NA NA NA NA NA NA NA 11386 FUN_000584 0 0 12 14 12 NA NA NA NA NA NA NA 11387 FUN_025265 0 33 31 18 8 NA NA NA NA NA NA NA 11388 FUN_019275 6 0 0 0 26 NA NA NA NA NA NA NA 11389 FUN_025267 0 0 12 0 93 NA NA NA NA NA NA NA 11390 FUN_025266 1567 1069 831 815 835 ptg000019l:590113-599089 O70475 3.7e-31 UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (UDP-GlcDH) (UDPGDH) (EC 1.1.1.22) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; gastrulation with mouth forming second [GO:0001702]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; neuron development [GO:0048666]; protein hexamerization [GO:0034214]; UDP-glucuronate biosynthetic process [GO:0006065] GO:0001702; GO:0003979; GO:0005634; GO:0005654; GO:0005829; GO:0005975; GO:0006024; GO:0006065; GO:0015012; GO:0030206; GO:0034214; GO:0042802; GO:0048666; GO:0051287 11391 FUN_025261 46 109 83 16 17 NA NA NA NA NA NA NA 11392 FUN_025260 1656 683 420 935 777 NA NA NA NA NA NA NA 11393 FUN_025263 2627 2167 941 1305 1104 NA NA NA NA NA NA NA 11394 FUN_025262 0 34 0 19 8 ptg000019l:543566-553971 O54991 2e-29 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 11395 FUN_019277 0 0 0 0 29 NA NA NA NA NA NA NA 11396 FUN_024798 654 570 399 570 512 ptg000018l:11189400-11199962 Q3U481 1.4e-31 Major facilitator superfamily domain-containing protein 12 (Protein grizzled) Mus musculus (Mouse) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 11397 FUN_024796 0 0 12 0 22 NA NA NA NA NA NA NA 11398 FUN_019271 0 0 0 0 22 NA NA NA NA NA NA NA 11399 FUN_024794 1493 1382 736 769 2521 NA NA NA NA NA NA NA 11400 FUN_024795 8 0 0 0 0 NA NA NA NA NA NA NA 11401 FUN_024793 0 0 0 16 0 NA NA NA NA NA NA NA 11402 FUN_019273 22 2 0 3 90 NA NA NA NA NA NA NA 11403 FUN_026616 0 0 0 0 28 NA NA NA NA NA NA NA 11404 FUN_038189 112 22 71 223 199 NA NA NA NA NA NA NA 11405 FUN_038184 42315 44875 19172 25548 14301 ptg000027l:3541302-3542430 A0A0R4IVA4 5.44e-87 Dual specificity protein phosphatase CDC14AB (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog AB) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096] GO:0000226; GO:0000922; GO:0004722; GO:0004725; GO:0005730; GO:0005737; GO:0005813; GO:0006470; GO:0007049; GO:0007096; GO:0008138; GO:0017018; GO:0032467; GO:0051301; GO:0060271; GO:0072686; GO:1902636 11406 FUN_038185 931 511 148 595 590 NA NA NA NA NA NA NA 11407 FUN_019515 0 0 0 12 0 NA NA NA NA NA NA NA 11408 FUN_019518 7 0 27 51 4 NA NA NA NA NA NA NA 11409 FUN_033113 74 0 23 59 57 ptg000023l:40014179-40029651 P21328 4.58e-28 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 11410 FUN_033113 74 0 23 59 57 ptg000023l:40014179-40029651 P21328 4.58e-28 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 11411 FUN_024138 1088 606 672 1217 712 ptg000018l:2604201-2623096 A1ZAX0 1.34e-21 Neuropeptide CCHamide-1 receptor Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008261; GO:0016020 11412 FUN_024139 2211 1934 682 1379 764 NA NA NA NA NA NA NA 11413 FUN_024132 312 190 122 86 203 ptg000018l:2547036-2549445 Q9ET55 1.11e-60 Nocturnin (EC 3.1.3.108) (Carbon catabolite repression 4-like protein) Rattus norvegicus (Rat) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; mRNA stabilization [GO:0048255]; NADP metabolic process [GO:0006739]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; P-body assembly [GO:0033962]; positive regulation of fat cell differentiation [GO:0045600]; regulation of circadian rhythm [GO:0042752]; regulation of embryonic development [GO:0045995]; response to extracellular stimulus [GO:0009991]; response to lipopolysaccharide [GO:0032496] GO:0000175; GO:0000290; GO:0000932; GO:0003729; GO:0004535; GO:0005634; GO:0005737; GO:0005739; GO:0006739; GO:0007623; GO:0009991; GO:0010629; GO:0019178; GO:0032496; GO:0032922; GO:0033962; GO:0042752; GO:0045600; GO:0045668; GO:0045995; GO:0046872; GO:0048255; GO:0048471; GO:0102757 11414 FUN_024133 728 211 357 516 486 ptg000018l:2549723-2565077 Q9NBX4 1.46e-37 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 11415 FUN_024130 542 397 335 505 439 ptg000018l:2541318-2542626 Q6ZWB6 9.07e-67 BTB/POZ domain-containing protein KCTD8 Homo sapiens (Human) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0008277; GO:0042734; GO:0042995; GO:0043235; GO:0045211; GO:0051260 11416 FUN_024131 28 23 14 64 27 NA NA NA NA NA NA NA 11417 FUN_024136 1612 909 502 1206 961 ptg000018l:2575679-2588070 A7SNN5 2.93e-44 Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) Nematostella vectensis (Starlet sea anemone) mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of cytokinesis [GO:0032465] GO:0000278; GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0006468; GO:0032465; GO:0106310 11418 FUN_024136 1612 909 502 1206 961 ptg000018l:2575679-2588070 A7SNN5 2.47e-28 Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) Nematostella vectensis (Starlet sea anemone) mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of cytokinesis [GO:0032465] GO:0000278; GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0006468; GO:0032465; GO:0106310 11419 FUN_024137 1638 743 1581 2322 896 NA NA NA NA NA NA NA 11420 FUN_024134 199 137 185 152 216 ptg000018l:2566780-2570260 O54991 1.39e-27 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 11421 FUN_024135 154 273 338 310 493 NA NA NA NA NA NA NA 11422 FUN_030629 14 0 0 21 0 NA NA NA NA NA NA NA 11423 FUN_030628 0 4 0 4 21 NA NA NA NA NA NA NA 11424 FUN_039639 0 0 0 84 85 NA NA NA NA NA NA NA 11425 FUN_030623 0 0 0 0 12 NA NA NA NA NA NA NA 11426 FUN_030621 16 0 12 0 13 NA NA NA NA NA NA NA 11427 FUN_030627 0 7 50 511 0 NA NA NA NA NA NA NA 11428 FUN_030626 0 7 44 598 0 NA NA NA NA NA NA NA 11429 FUN_030625 34 37 30 45 26 NA NA NA NA NA NA NA 11430 FUN_039706 0 59 30 0 21 NA NA NA NA NA NA NA 11431 FUN_039703 7 7 15 0 61 NA NA NA NA NA NA NA 11432 FUN_039702 436 197 358 530 288 NA NA NA NA NA NA NA 11433 FUN_039701 6428 6347 4236 4672 4967 NA NA NA NA NA NA NA 11434 FUN_014744 6 0 6 0 0 NA NA NA NA NA NA NA 11435 FUN_041447 38 28 2 55 21 NA NA NA NA NA NA NA 11436 FUN_036704 0 0 0 0 8 NA NA NA NA NA NA NA 11437 FUN_036705 38 3 0 5 8 NA NA NA NA NA NA NA 11438 FUN_036702 44 3 34 0 70 NA NA NA NA NA NA NA 11439 FUN_006134 7 0 0 0 0 NA NA NA NA NA NA NA 11440 FUN_006135 122 234 53 12 64 ptg000001l:8176204-8256938 B8V7S0 5.19e-89 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 11441 FUN_006135 122 234 53 12 64 ptg000001l:8176204-8256938 B8V7S0 1.85e-86 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 11442 FUN_006135 122 234 53 12 64 ptg000001l:8176204-8256938 B8V7S0 6.82e-22 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 11443 FUN_006132 132 39 22 129 19 NA NA NA NA NA NA NA 11444 FUN_006133 26 0 0 15 0 NA NA NA NA NA NA NA 11445 FUN_006130 38 1115 11 149 943 NA NA NA NA NA NA NA 11446 FUN_006131 40 643 32 1058 351 NA NA NA NA NA NA NA 11447 FUN_031282 20 132 23 110 34 ptg000023l:18850295-18864417 Q6ITT3 6.76e-64 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 11448 FUN_031283 23 0 0 0 15 NA NA NA NA NA NA NA 11449 FUN_031286 1011 719 537 1052 1141 NA NA NA NA NA NA NA 11450 FUN_031287 2012 1167 955 1492 1396 ptg000023l:18949194-18962307 Q9Y597 1.74e-45 BTB/POZ domain-containing protein KCTD3 (Renal carcinoma antigen NY-REN-45) Homo sapiens (Human) protein homooligomerization [GO:0051260] GO:0005886; GO:0051260 11451 FUN_031285 0 7 2 5 8 NA NA NA NA NA NA NA 11452 FUN_031288 5851 4682 2738 3998 2111 NA NA NA NA NA NA NA 11453 FUN_031289 2511 1081 974 2920 2895 NA NA NA NA NA NA NA 11454 FUN_006680 0 5 5 11 5 NA NA NA NA NA NA NA 11455 FUN_006681 65 86 23 53 24 NA NA NA NA NA NA NA 11456 FUN_006682 0 11 7 4 9 NA NA NA NA NA NA NA 11457 FUN_006683 2 0 0 22 3 NA NA NA NA NA NA NA 11458 FUN_006684 36 84 0 49 0 NA NA NA NA NA NA NA 11459 FUN_006685 1864 698 335 1705 274 NA NA NA NA NA NA NA 11460 FUN_006686 0 0 0 345 23 NA NA NA NA NA NA NA 11461 FUN_006687 17 26 28 577 0 NA NA NA NA NA NA NA 11462 FUN_006688 4310 2018 1002 2767 1001 NA NA NA NA NA NA NA 11463 FUN_006689 156 111 0 196 15 NA NA NA NA NA NA NA 11464 FUN_041443 146 86 61 53 141 NA NA NA NA NA NA NA 11465 FUN_042925 217 978 538 0 270 NA NA NA NA NA NA NA 11466 FUN_016607 3788 3918 4200 3870 4977 NA NA NA NA NA NA NA 11467 FUN_016606 97 130 125 104 135 NA NA NA NA NA NA NA 11468 FUN_042921 6 22 10 3 13 NA NA NA NA NA NA NA 11469 FUN_016600 43 0 69 18 84 NA NA NA NA NA NA NA 11470 FUN_042923 3432 3023 1904 804 3467 ptg000047l:1808115-1843997 P0CT40 6.63e-64 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 11471 FUN_042923 3432 3023 1904 804 3467 ptg000047l:1808115-1843997 P0CT40 6.63e-64 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 11472 FUN_042923 3432 3023 1904 804 3467 ptg000047l:1808115-1843997 P0CT40 6.63e-64 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 11473 FUN_001489 22 42 39 21 12 NA NA NA NA NA NA NA 11474 FUN_001488 0 0 0 9 0 ntLink_6:12830445-12862163 Q96DM1 6.51e-29 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 11475 FUN_001487 12 2 4 16 21 NA NA NA NA NA NA NA 11476 FUN_001486 27 12 5 21 41 NA NA NA NA NA NA NA 11477 FUN_001485 4 106 60 51 56 NA NA NA NA NA NA NA 11478 FUN_042922 57 200 169 3 64 NA NA NA NA NA NA NA 11479 FUN_001483 10208 6405 3898 6679 3999 ntLink_6:12793848-12803001 P31409 3.05e-27 V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 55 kDa subunit) (Vacuolar proton pump subunit B) Drosophila melanogaster (Fruit fly) ATP metabolic process [GO:0046034]; proton transmembrane transport [GO:1902600]; vacuolar acidification [GO:0007035] GO:0000221; GO:0005524; GO:0005769; GO:0005829; GO:0005886; GO:0005903; GO:0007035; GO:0033181; GO:0046034; GO:0046961; GO:0048471; GO:1902600 11480 FUN_001483 10208 6405 3898 6679 3999 ntLink_6:12793848-12803001 P31409 3.05e-27 V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 55 kDa subunit) (Vacuolar proton pump subunit B) Drosophila melanogaster (Fruit fly) ATP metabolic process [GO:0046034]; proton transmembrane transport [GO:1902600]; vacuolar acidification [GO:0007035] GO:0000221; GO:0005524; GO:0005769; GO:0005829; GO:0005886; GO:0005903; GO:0007035; GO:0033181; GO:0046034; GO:0046961; GO:0048471; GO:1902600 11481 FUN_001481 619 253 209 349 315 NA NA NA NA NA NA NA 11482 FUN_001480 26 15 11 6 23 ntLink_6:12781403-12782921 Q91770 3.82e-25 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 11483 FUN_003584 10 0 0 0 33 NA NA NA NA NA NA NA 11484 FUN_023700 3211 1142 2088 3041 3798 NA NA NA NA NA NA NA 11485 FUN_003587 98 42 60 108 158 NA NA NA NA NA NA NA 11486 FUN_041440 206 188 90 136 87 NA NA NA NA NA NA NA 11487 FUN_042928 57 20 8 12 7 NA NA NA NA NA NA NA 11488 FUN_010030 12 0 0 21 0 NA NA NA NA NA NA NA 11489 FUN_010031 16 9 23 2 179 NA NA NA NA NA NA NA 11490 FUN_003583 26 0 0 0 32 NA NA NA NA NA NA NA 11491 FUN_040713 975 843 489 546 767 ptg000031l:12292241-12299727 Q9Z2E1 8.17e-35 Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) Mus musculus (Mouse) aging [GO:0007568]; cellular response to organic cyclic compound [GO:0071407]; chromatin remodeling [GO:0006338]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic organ development [GO:0048568]; heart development [GO:0007507]; histone deacetylation [GO:0016575]; maternal behavior [GO:0042711]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of chromatin binding [GO:0035563]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of Wnt signaling pathway [GO:0030177]; protein-containing complex assembly [GO:0065003]; regulation of cell population proliferation [GO:0042127]; regulation of DNA methylation [GO:0044030]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; response to nutrient levels [GO:0031667]; Wnt signaling pathway [GO:0016055] GO:0000118; GO:0000122; GO:0000785; GO:0000792; GO:0003677; GO:0003682; GO:0003729; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006338; GO:0006346; GO:0007507; GO:0007568; GO:0008327; GO:0009612; GO:0016055; GO:0016575; GO:0016581; GO:0019904; GO:0030177; GO:0031667; GO:0032355; GO:0035197; GO:0035563; GO:0042127; GO:0042711; GO:0044030; GO:0045893; GO:0048568; GO:0060090; GO:0065003; GO:0070742; GO:0071407 11492 FUN_033628 8 0 0 0 0 NA NA NA NA NA NA NA 11493 FUN_033627 1 0 3 6 4 NA NA NA NA NA NA NA 11494 FUN_033625 2 3 2 4 99 NA NA NA NA NA NA NA 11495 FUN_033622 0 25 0 0 0 NA NA NA NA NA NA NA 11496 FUN_033620 18 0 0 0 0 NA NA NA NA NA NA NA 11497 FUN_033621 411 311 247 0 0 NA NA NA NA NA NA NA 11498 FUN_040716 735 641 400 1051 639 NA NA NA NA NA NA NA 11499 FUN_040717 964 623 217 491 258 NA NA NA NA NA NA NA 11500 FUN_000210 4894 1833 1929 4098 3810 ntLink_6:299039-313127 Q9NZ08 2.82e-21 Endoplasmic reticulum aminopeptidase 1 (EC 3.4.11.-) (ARTS-1) (Adipocyte-derived leucine aminopeptidase) (A-LAP) (Aminopeptidase PILS) (Puromycin-insensitive leucyl-specific aminopeptidase) (PILS-AP) (Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator) Homo sapiens (Human) adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; antigen processing and presentation of peptide antigen via MHC class I [GO:0002474]; fat cell differentiation [GO:0045444]; membrane protein ectodomain proteolysis [GO:0006509]; peptide catabolic process [GO:0043171]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; regulation of innate immune response [GO:0045088]; response to bacterium [GO:0009617]; signal transduction [GO:0007165] GO:0001525; GO:0002250; GO:0002474; GO:0004175; GO:0004177; GO:0005138; GO:0005151; GO:0005576; GO:0005615; GO:0005737; GO:0005783; GO:0005788; GO:0005789; GO:0005829; GO:0005886; GO:0006508; GO:0006509; GO:0007165; GO:0008217; GO:0008235; GO:0008270; GO:0009617; GO:0016020; GO:0019885; GO:0042277; GO:0043171; GO:0045088; GO:0045444; GO:0045766; GO:0070006; GO:0070062 11501 FUN_023703 487 198 352 542 556 NA NA NA NA NA NA NA 11502 FUN_000212 2151 1521 943 2273 1007 ntLink_6:321936-332803 Q6K4E7 1.62e-28 Aminopeptidase M1-D (EC 3.4.11.2) (Alpha-aminoacylpeptide hydrolase) Oryza sativa subsp. japonica (Rice) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0005737; GO:0005783; GO:0006508; GO:0008270; GO:0016020; GO:0042277; GO:0043171; GO:0070006 11503 FUN_031918 0 0 0 10 0 ptg000023l:26737450-26738743 A9C3R8 2.86e-39 Retinal Mueller cells isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl ester 13-cis isomerohydrolase C) (EC 3.1.1.90) (All-trans-retinylester 11-cis isomerohydrolase C) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog C) (RPE56c) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005829; GO:0005886; GO:0016020; GO:0016702; GO:0046872; GO:0050251; GO:0052884; GO:0052885; GO:1901827 11504 FUN_031919 354 239 23 187 589 ptg000023l:26744457-26747304 A9C3R9 1.34e-44 All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005886; GO:0016702; GO:0016787; GO:0046872; GO:0050251; GO:1901827 11505 FUN_031919 354 239 23 187 589 ptg000023l:26744457-26747304 A9C3R9 6.41e-28 All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005886; GO:0016702; GO:0016787; GO:0046872; GO:0050251; GO:1901827 11506 FUN_031912 7 0 14 670 0 NA NA NA NA NA NA NA 11507 FUN_031913 1100 348 556 388 427 NA NA NA NA NA NA NA 11508 FUN_031910 71 0 28 102 172 NA NA NA NA NA NA NA 11509 FUN_031916 2520 1099 959 2433 1323 ptg000023l:26730568-26733504 A9C3R9 2.16e-44 All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005886; GO:0016702; GO:0016787; GO:0046872; GO:0050251; GO:1901827 11510 FUN_031916 2520 1099 959 2433 1323 ptg000023l:26730568-26733504 A9C3R9 1.69e-22 All-trans-retinyl ester 13-cis isomerohydrolase (13cIMH) (EC 3.1.1.90) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein homolog B) (RPE56b) Danio rerio (Zebrafish) (Brachydanio rerio) retinoid metabolic process [GO:0001523]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0005789; GO:0005886; GO:0016702; GO:0016787; GO:0046872; GO:0050251; GO:1901827 11511 FUN_031917 47 23 48 58 17 ptg000023l:26735804-26737111 Q8HXG8 3.07e-25 Carotenoid-cleaving dioxygenase, mitochondrial (EC 1.13.11.-) (EC 1.13.11.71) (Beta-carotene dioxygenase 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) carotene catabolic process [GO:0016121]; carotene metabolic process [GO:0016119]; lutein catabolic process [GO:0062172]; lycopene catabolic process [GO:1901176]; xanthophyll catabolic process [GO:0016124]; zeaxanthin catabolic process [GO:1901826] GO:0005739; GO:0010437; GO:0016119; GO:0016121; GO:0016124; GO:0016702; GO:0046872; GO:0062172; GO:0102076; GO:1901176; GO:1901826 11512 FUN_031914 1122 108 92 1177 328 NA NA NA NA NA NA NA 11513 FUN_031915 75 53 88 117 142 ptg000023l:26725907-26728433 O00222 6.17e-145 Metabotropic glutamate receptor 8 (mGluR8) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; regulation of synaptic transmission, glutamatergic [GO:0051966]; visual perception [GO:0007601] GO:0001640; GO:0001642; GO:0004930; GO:0005886; GO:0007193; GO:0007196; GO:0007216; GO:0007601; GO:0008066; GO:0051966 11514 FUN_018369 15 6 2 1 0 NA NA NA NA NA NA NA 11515 FUN_034399 3748 5663 4839 2322 4522 NA NA NA NA NA NA NA 11516 FUN_034398 140 61 51 46 143 NA NA NA NA NA NA NA 11517 FUN_018364 75 0 11 141 16 NA NA NA NA NA NA NA 11518 FUN_018365 19 0 3 2 5 NA NA NA NA NA NA NA 11519 FUN_034395 3493 3108 2152 4438 3269 NA NA NA NA NA NA NA 11520 FUN_034394 93 33 12 55 36 NA NA NA NA NA NA NA 11521 FUN_018360 3493 317 678 1777 1273 NA NA NA NA NA NA NA 11522 FUN_018361 348 422 398 864 498 ptg000012l:8397510-8420546 P14381 1.63e-36 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 11523 FUN_018361 348 422 398 864 498 ptg000012l:8397510-8420546 P14381 1.63e-36 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 11524 FUN_018362 4123 397 486 210 272 ptg000012l:8450396-8466933 Q96AY4 1.15e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11525 FUN_018362 4123 397 486 210 272 ptg000012l:8450396-8466933 Q96AY4 2.65e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11526 FUN_018362 4123 397 486 210 272 ptg000012l:8450396-8466933 Q96AY4 1.18e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11527 FUN_018362 4123 397 486 210 272 ptg000012l:8450396-8466933 Q96AY4 1.1e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11528 FUN_018362 4123 397 486 210 272 ptg000012l:8450396-8466933 Q96AY4 5.51e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11529 FUN_018362 4123 397 486 210 272 ptg000012l:8450396-8466933 Q96AY4 1.77e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11530 FUN_018363 25 0 8 122 14 NA NA NA NA NA NA NA 11531 FUN_006918 212 205 170 317 392 NA NA NA NA NA NA NA 11532 FUN_006919 3167 1498 2432 3661 3563 ptg000001l:18304901-18326764 Q61687 1.31e-22 Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (HP1 alpha-interacting protein) (HP1-BP38 protein) (Heterochromatin protein 2) (X-linked nuclear protein) Mus musculus (Mouse) cellular response to hydroxyurea [GO:0072711]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; chromosome organization involved in meiotic cell cycle [GO:0070192]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA repair [GO:0006281]; forebrain development [GO:0030900]; meiotic spindle organization [GO:0000212]; multicellular organism growth [GO:0035264]; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric [GO:1904908]; nucleosome assembly [GO:0006334]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomeric RNA transcription from RNA pol II promoter [GO:1901582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic forelimb morphogenesis [GO:0035128]; protein localization to chromosome, telomeric region [GO:0070198]; regulation of histone H3-K9 trimethylation [GO:1900112]; replication fork processing [GO:0031297]; seminiferous tubule development [GO:0072520]; Sertoli cell development [GO:0060009]; spermatogenesis [GO:0007283]; subtelomeric heterochromatin formation [GO:0031509]; transcription by RNA polymerase II [GO:0006366] GO:0000212; GO:0000228; GO:0000779; GO:0000781; GO:0000792; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005721; GO:0005737; GO:0006281; GO:0006325; GO:0006334; GO:0006338; GO:0006366; GO:0007283; GO:0010571; GO:0015616; GO:0016604; GO:0016605; GO:0016887; GO:0030330; GO:0030900; GO:0031297; GO:0031490; GO:0031509; GO:0032206; GO:0035064; GO:0035128; GO:0035264; GO:0042393; GO:0045944; GO:0046872; GO:0060009; GO:0070087; GO:0070192; GO:0070198; GO:0072520; GO:0072711; GO:0099115; GO:0140658; GO:1900112; GO:1901582; GO:1904908 11533 FUN_031681 1580 1523 1064 2042 1237 NA NA NA NA NA NA NA 11534 FUN_006911 74 232 30 96 41 NA NA NA NA NA NA NA 11535 FUN_006912 24 392 43 124 13 NA NA NA NA NA NA NA 11536 FUN_006913 39 121 20 0 7 NA NA NA NA NA NA NA 11537 FUN_006915 77 1076 63 237 64 NA NA NA NA NA NA NA 11538 FUN_006916 44 216 24 338 18 NA NA NA NA NA NA NA 11539 FUN_006917 8710 6704 4715 5003 4734 ptg000001l:18290248-18298010 E2RQ08 1.69e-35 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Ribophorin I) (RPN-I) (Ribophorin-1) Canis lupus familiaris (Dog) (Canis familiaris) protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0005791; GO:0005829; GO:0006486; GO:0008250; GO:0018279 11540 FUN_006917 8710 6704 4715 5003 4734 ptg000001l:18290248-18298010 E2RQ08 5.08e-29 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Ribophorin I) (RPN-I) (Ribophorin-1) Canis lupus familiaris (Dog) (Canis familiaris) protein glycosylation [GO:0006486]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0005791; GO:0005829; GO:0006486; GO:0008250; GO:0018279 11541 FUN_000556 102 54 33 50 52 NA NA NA NA NA NA NA 11542 FUN_028602 0 0 0 0 64 ptg000022l:1308266-1319466 Q9NBX4 2.31e-22 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 11543 FUN_028602 0 0 0 0 64 ptg000022l:1308266-1319466 Q9NBX4 2.31e-22 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 11544 FUN_035116 197 94 81 0 0 NA NA NA NA NA NA NA 11545 FUN_035117 753 312 209 46 0 NA NA NA NA NA NA NA 11546 FUN_035114 1111 408 48 252 331 NA NA NA NA NA NA NA 11547 FUN_000557 36 49 46 77 51 NA NA NA NA NA NA NA 11548 FUN_005110 299 129 103 137 240 NA NA NA NA NA NA NA 11549 FUN_035113 313 174 355 513 444 NA NA NA NA NA NA NA 11550 FUN_035110 7 0 0 0 0 NA NA NA NA NA NA NA 11551 FUN_035119 537 1188 27 93 203 NA NA NA NA NA NA NA 11552 FUN_000554 770 1655 1049 1025 889 NA NA NA NA NA NA NA 11553 FUN_041566 1643 1396 1005 1077 1471 ptg000035l:5314716-5331604 P57080 5.34e-33 Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (mUSP25) Mus musculus (Mouse) I-kappaB phosphorylation [GO:0007252]; immune response [GO:0006955]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA metabolic process [GO:0016071]; negative regulation of ERAD pathway [GO:1904293]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536]; response to oxidative stress [GO:0006979]; stress-activated protein kinase signaling cascade [GO:0031098]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0004197; GO:0004843; GO:0005634; GO:0005783; GO:0005829; GO:0006511; GO:0006955; GO:0006979; GO:0007252; GO:0016071; GO:0016579; GO:0031098; GO:0031625; GO:0032183; GO:0051117; GO:0070536; GO:0071108; GO:0097400; GO:1904293 11554 FUN_043261 1914 713 1233 2412 1830 ptg000047l:6118615-6158504 Q7Z7G8 1.23e-69 Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) Homo sapiens (Human) acrosome assembly [GO:0001675]; adipose tissue development [GO:0060612]; central nervous system development [GO:0007417]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; lipid transport [GO:0006869]; maintenance of lens transparency [GO:0036438]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; slow endocytic recycling [GO:0032458]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001675; GO:0002080; GO:0005765; GO:0006869; GO:0007030; GO:0007399; GO:0007417; GO:0016192; GO:0031175; GO:0031901; GO:0032266; GO:0032458; GO:0032588; GO:0033106; GO:0033116; GO:0036438; GO:0055038; GO:0060612; GO:0090168 11555 FUN_043261 1914 713 1233 2412 1830 ptg000047l:6118615-6158504 Q7Z7G8 1.14e-67 Intermembrane lipid transfer protein VPS13B (Cohen syndrome protein 1) (Vacuolar protein sorting-associated protein 13B) Homo sapiens (Human) acrosome assembly [GO:0001675]; adipose tissue development [GO:0060612]; central nervous system development [GO:0007417]; Golgi organization [GO:0007030]; Golgi reassembly [GO:0090168]; lipid transport [GO:0006869]; maintenance of lens transparency [GO:0036438]; nervous system development [GO:0007399]; neuron projection development [GO:0031175]; slow endocytic recycling [GO:0032458]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0001675; GO:0002080; GO:0005765; GO:0006869; GO:0007030; GO:0007399; GO:0007417; GO:0016192; GO:0031175; GO:0031901; GO:0032266; GO:0032458; GO:0032588; GO:0033106; GO:0033116; GO:0036438; GO:0055038; GO:0060612; GO:0090168 11556 FUN_043260 1876 1433 719 1439 870 NA NA NA NA NA NA NA 11557 FUN_043263 319 341 87 267 128 NA NA NA NA NA NA NA 11558 FUN_043262 49 21 42 0 169 ptg000047l:6159494-6164504 O00311 5.88e-23 Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) (EC 2.7.11.1) Homo sapiens (Human) cell cycle phase transition [GO:0044770]; cell division [GO:0051301]; double-strand break repair via break-induced replication [GO:0000727]; G1/S transition of mitotic cell cycle [GO:0000082]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of nuclear cell cycle DNA replication [GO:0010571]; signal transduction [GO:0007165] GO:0000082; GO:0000727; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0007165; GO:0008284; GO:0010571; GO:0010971; GO:0016301; GO:0018105; GO:0044770; GO:0045171; GO:0046872; GO:0051301; GO:0072686; GO:0106310 11559 FUN_043265 116 104 91 127 125 NA NA NA NA NA NA NA 11560 FUN_043264 318 818 547 771 232 NA NA NA NA NA NA NA 11561 FUN_043267 145 221 72 61 112 NA NA NA NA NA NA NA 11562 FUN_043266 135 119 110 131 110 NA NA NA NA NA NA NA 11563 FUN_043269 23 64 59 8 52 NA NA NA NA NA NA NA 11564 FUN_043268 102 88 62 97 138 NA NA NA NA NA NA NA 11565 FUN_013051 493 32 111 11 175 NA NA NA NA NA NA NA 11566 FUN_013057 347 460 363 290 342 NA NA NA NA NA NA NA 11567 FUN_013056 25053 8078 6027 5205 3575 NA NA NA NA NA NA NA 11568 FUN_013055 45 0 2 40 0 NA NA NA NA NA NA NA 11569 FUN_013054 0 0 20 0 3 NA NA NA NA NA NA NA 11570 FUN_036056 75 19 25 50 20 NA NA NA NA NA NA NA 11571 FUN_031001 0 0 71 0 0 NA NA NA NA NA NA NA 11572 FUN_031002 151 35 47 53 257 NA NA NA NA NA NA NA 11573 FUN_036055 603 371 485 338 910 ptg000025l:14921346-14933470 O43422 4.37e-30 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 11574 FUN_031004 16 0 23 43 83 NA NA NA NA NA NA NA 11575 FUN_040205 5161 5303 2009 3847 3589 NA NA NA NA NA NA NA 11576 FUN_031005 15 0 18 0 33 NA NA NA NA NA NA NA 11577 FUN_036050 0 0 14 0 16 NA NA NA NA NA NA NA 11578 FUN_031007 0 0 0 8 0 NA NA NA NA NA NA NA 11579 FUN_000550 233 344 174 932 414 NA NA NA NA NA NA NA 11580 FUN_002114 15 36 13 40 43 NA NA NA NA NA NA NA 11581 FUN_002115 2039 779 699 1372 1497 ntLink_6:20130251-20184735 P14381 1.6e-21 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 11582 FUN_002116 72 39 26 35 72 NA NA NA NA NA NA NA 11583 FUN_002117 192 30 80 43 73 NA NA NA NA NA NA NA 11584 FUN_002110 0 0 41 0 90 NA NA NA NA NA NA NA 11585 FUN_002111 7 4 5 10 21 NA NA NA NA NA NA NA 11586 FUN_002112 9 0 0 0 15 ntLink_6:20106852-20110394 P04323 4.6e-24 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 11587 FUN_002112 9 0 0 0 15 ntLink_6:20106852-20110394 P04323 4.6e-24 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 11588 FUN_002119 20 0 17 30 15 NA NA NA NA NA NA NA 11589 FUN_010936 128 1773 62 203 522 ptg000007l:4462496-4474844 A0ZSK3 1.5e-78 Neoverrucotoxin subunit alpha (NeoVTX subunit alpha) Synanceia verrucosa (Reef stonefish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 11590 FUN_018134 149 67 0 169 176 NA NA NA NA NA NA NA 11591 FUN_042609 258 294 254 264 143 NA NA NA NA NA NA NA 11592 FUN_042600 101 45 8 21 0 NA NA NA NA NA NA NA 11593 FUN_042601 73 50 131 127 177 NA NA NA NA NA NA NA 11594 FUN_042602 2205 1043 1233 2134 1765 NA NA NA NA NA NA NA 11595 FUN_042603 0 0 8 3 4 NA NA NA NA NA NA NA 11596 FUN_042604 3970 6341 1972 1677 1089 ptg000039l:249497-254646 Q95KD9 2.81e-30 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165 11597 FUN_042605 166 117 77 216 361 ptg000039l:255031-276806 Q6MG62 4.46e-24 MutS protein homolog 5 Rattus norvegicus (Rat) chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; meiosis I [GO:0007127]; mismatch repair [GO:0006298] GO:0000795; GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0007127; GO:0007129; GO:0007292; GO:0030983; GO:0051026; GO:0140664 11598 FUN_042605 166 117 77 216 361 ptg000039l:255031-276806 Q6MG62 4.46e-24 MutS protein homolog 5 Rattus norvegicus (Rat) chiasma assembly [GO:0051026]; female gamete generation [GO:0007292]; homologous chromosome pairing at meiosis [GO:0007129]; meiosis I [GO:0007127]; mismatch repair [GO:0006298] GO:0000795; GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0007127; GO:0007129; GO:0007292; GO:0030983; GO:0051026; GO:0140664 11599 FUN_042606 63639 80854 34793 63621 29968 ptg000039l:279096-284788 Q6VTH5 2.26e-44 Radial spoke head 1 homolog (Meichroacidin homolog) (Meichroacidin-like sperm-specific axonemal protein) (Testis-specific gene A2-like protein) Cyprinus carpio (Common carp) cell differentiation [GO:0030154]; meiotic cell cycle [GO:0051321]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0007283; GO:0030154; GO:0031514; GO:0051321 11600 FUN_042607 1398 24 308 947 615 NA NA NA NA NA NA NA 11601 FUN_044195 1 0 4 3 9 NA NA NA NA NA NA NA 11602 FUN_035517 0 0 7 21 46 NA NA NA NA NA NA NA 11603 FUN_012861 0 0 0 0 21 NA NA NA NA NA NA NA 11604 FUN_012869 0 2 0 8 59 NA NA NA NA NA NA NA 11605 FUN_035515 0 0 10 4 12 NA NA NA NA NA NA NA 11606 FUN_011987 1914 1594 1215 3138 2185 NA NA NA NA NA NA NA 11607 FUN_011986 937 1117 427 741 1357 NA NA NA NA NA NA NA 11608 FUN_011985 932 657 760 905 1212 ptg000008l:3827367-3838841 P21872 3.69e-50 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084]; purine nucleotide biosynthetic process [GO:0006164] GO:0004637; GO:0004641; GO:0004644; GO:0005524; GO:0005829; GO:0006164; GO:0006189; GO:0046084; GO:0046872 11609 FUN_011985 932 657 760 905 1212 ptg000008l:3827367-3838841 P21872 1.03e-33 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084]; purine nucleotide biosynthetic process [GO:0006164] GO:0004637; GO:0004641; GO:0004644; GO:0005524; GO:0005829; GO:0006164; GO:0006189; GO:0046084; GO:0046872 11610 FUN_011985 932 657 760 905 1212 ptg000008l:3827367-3838841 P21872 1.96e-30 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084]; purine nucleotide biosynthetic process [GO:0006164] GO:0004637; GO:0004641; GO:0004644; GO:0005524; GO:0005829; GO:0006164; GO:0006189; GO:0046084; GO:0046872 11611 FUN_011985 932 657 760 905 1212 ptg000008l:3827367-3838841 P21872 6.03e-30 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084]; purine nucleotide biosynthetic process [GO:0006164] GO:0004637; GO:0004641; GO:0004644; GO:0005524; GO:0005829; GO:0006164; GO:0006189; GO:0046084; GO:0046872 11612 FUN_011985 932 657 760 905 1212 ptg000008l:3827367-3838841 P21872 6.93e-25 Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189]; adenine biosynthetic process [GO:0046084]; purine nucleotide biosynthetic process [GO:0006164] GO:0004637; GO:0004641; GO:0004644; GO:0005524; GO:0005829; GO:0006164; GO:0006189; GO:0046084; GO:0046872 11613 FUN_011984 5688 3912 2498 6079 4788 NA NA NA NA NA NA NA 11614 FUN_011983 2114 1008 1849 1172 177 NA NA NA NA NA NA NA 11615 FUN_011982 1555 865 1257 1174 80 NA NA NA NA NA NA NA 11616 FUN_011981 1744 1657 1030 1498 1070 NA NA NA NA NA NA NA 11617 FUN_011980 0 0 0 0 8 NA NA NA NA NA NA NA 11618 FUN_011989 1841 1647 1006 1718 1916 NA NA NA NA NA NA NA 11619 FUN_009858 940 866 575 784 438 NA NA NA NA NA NA NA 11620 FUN_009859 374 339 119 537 187 NA NA NA NA NA NA NA 11621 FUN_002808 866 508 224 663 462 NA NA NA NA NA NA NA 11622 FUN_002802 31 0 0 110 49 NA NA NA NA NA NA NA 11623 FUN_002801 1413 766 812 1612 7107 NA NA NA NA NA NA NA 11624 FUN_002807 923 624 584 906 944 NA NA NA NA NA NA NA 11625 FUN_002804 71 0 0 24 38 NA NA NA NA NA NA NA 11626 FUN_002805 771 462 380 613 609 NA NA NA NA NA NA NA 11627 FUN_029913 10 0 0 0 0 NA NA NA NA NA NA NA 11628 FUN_032255 426 233 160 278 221 ptg000023l:30264724-30271354 O43909 6.73e-106 Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3) Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of cell growth [GO:0030307]; protein glycosylation [GO:0006486] GO:0000287; GO:0001888; GO:0005783; GO:0005789; GO:0005794; GO:0006486; GO:0015012; GO:0016757; GO:0030307 11629 FUN_032255 426 233 160 278 221 ptg000023l:30264724-30271354 O43909 2.75e-23 Exostosin-like 3 (EC 2.4.1.223) (EXT-related protein 1) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Hereditary multiple exostoses gene isolog) (Multiple exostosis-like protein 3) (Putative tumor suppressor protein EXTL3) Homo sapiens (Human) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of cell growth [GO:0030307]; protein glycosylation [GO:0006486] GO:0000287; GO:0001888; GO:0005783; GO:0005789; GO:0005794; GO:0006486; GO:0015012; GO:0016757; GO:0030307 11630 FUN_005650 0 0 6 0 30 NA NA NA NA NA NA NA 11631 FUN_032256 8 4 0 1 3 NA NA NA NA NA NA NA 11632 FUN_029910 18 2 9 4 32 NA NA NA NA NA NA NA 11633 FUN_008189 248 86 88 205 170 NA NA NA NA NA NA NA 11634 FUN_008188 2260 789 730 1912 908 ptg000002l:9099024-9108546 Q99NB1 9.2e-39 Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) (Propionate--CoA ligase) (EC 6.2.1.17) Mus musculus (Mouse) acetate biosynthetic process [GO:0019413]; acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; propionate biosynthetic process [GO:0019542] GO:0003987; GO:0005524; GO:0005739; GO:0005759; GO:0006085; GO:0016208; GO:0019413; GO:0019427; GO:0019542; GO:0050218 11635 FUN_008185 1700 1442 2015 1972 560 ptg000002l:9060131-9062072 Q8BQH6 8.17e-51 CUB domain-containing protein 2 Mus musculus (Mouse) NA GO:0005576 11636 FUN_008184 13 8 0 15 16 NA NA NA NA NA NA NA 11637 FUN_008187 1607 1265 698 1078 842 ptg000002l:9082758-9094618 O75582 1.02e-31 Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) Homo sapiens (Human) axon guidance [GO:0007411]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; regulation of postsynapse organization [GO:0099175] GO:0000287; GO:0001818; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006355; GO:0006468; GO:0006954; GO:0007411; GO:0018105; GO:0032793; GO:0035175; GO:0035556; GO:0043687; GO:0044022; GO:0044024; GO:0045892; GO:0045944; GO:0051092; GO:0070498; GO:0099175; GO:0106310 11638 FUN_008187 1607 1265 698 1078 842 ptg000002l:9082758-9094618 O75582 1.02e-31 Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL) Homo sapiens (Human) axon guidance [GO:0007411]; inflammatory response [GO:0006954]; interleukin-1-mediated signaling pathway [GO:0070498]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production [GO:0001818]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-translational protein modification [GO:0043687]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; regulation of postsynapse organization [GO:0099175] GO:0000287; GO:0001818; GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006355; GO:0006468; GO:0006954; GO:0007411; GO:0018105; GO:0032793; GO:0035175; GO:0035556; GO:0043687; GO:0044022; GO:0044024; GO:0045892; GO:0045944; GO:0051092; GO:0070498; GO:0099175; GO:0106310 11639 FUN_008186 2355 1257 1244 1687 2044 NA NA NA NA NA NA NA 11640 FUN_008181 21 0 0 0 0 NA NA NA NA NA NA NA 11641 FUN_008180 0 0 0 9 8 NA NA NA NA NA NA NA 11642 FUN_008183 593 488 356 589 586 NA NA NA NA NA NA NA 11643 FUN_008182 422 903 258 932 449 NA NA NA NA NA NA NA 11644 FUN_032236 103 55 60 62 126 NA NA NA NA NA NA NA 11645 FUN_032237 158 156 290 292 378 ptg000023l:30020933-30026514 P51029 2.02e-24 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 11646 FUN_032237 158 156 290 292 378 ptg000023l:30020933-30026514 P51029 1.59e-23 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 11647 FUN_032234 308 311 312 358 608 NA NA NA NA NA NA NA 11648 FUN_038170 112 70 152 66 54 ptg000027l:3387568-3391893 Q49SH1 7.23e-97 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 11649 FUN_038170 112 70 152 66 54 ptg000027l:3387568-3391893 Q49SH1 1.03e-79 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 11650 FUN_032232 853 1778 639 707 1762 NA NA NA NA NA NA NA 11651 FUN_032230 0 5 0 2 8 NA NA NA NA NA NA NA 11652 FUN_032231 163 1618 269 1552 868 ptg000023l:29916022-29923351 Q2KIN6 8.87e-34 Protein Mpv17 Bos taurus (Bovine) regulation of mitochondrial DNA metabolic process [GO:1901858] GO:0005737; GO:0005743; GO:0015267; GO:1901858 11653 FUN_029974 6 0 0 0 0 NA NA NA NA NA NA NA 11654 FUN_032238 711 627 377 737 563 NA NA NA NA NA NA NA 11655 FUN_034345 887 751 375 657 430 ptg000024l:7907741-7912628 P19477 1.92e-39 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 11656 FUN_011362 47 0 0 0 14 NA NA NA NA NA NA NA 11657 FUN_016069 3813 4728 2066 4725 3120 ptg000010l:1268613-1271133 P42653 9.2e-41 14-3-3-like protein A (VFA-1433A) Vicia faba (Broad bean) (Faba vulgaris) NA NA 11658 FUN_016069 3813 4728 2066 4725 3120 ptg000010l:1268613-1271133 P42653 2.86e-25 14-3-3-like protein A (VFA-1433A) Vicia faba (Broad bean) (Faba vulgaris) NA NA 11659 FUN_011367 19 0 4 10 5 NA NA NA NA NA NA NA 11660 FUN_011366 0 0 15 0 36 NA NA NA NA NA NA NA 11661 FUN_011365 0 3 48 6 0 NA NA NA NA NA NA NA 11662 FUN_011364 36 0 0 0 0 NA NA NA NA NA NA NA 11663 FUN_026982 4876 4068 2182 2869 1963 ptg000020l:15472250-15483293 P31939 1.02e-32 Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Cleaved into: Bifunctional purine biosynthesis protein ATIC, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)] Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; GMP biosynthetic process [GO:0006177]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654] GO:0003360; GO:0003937; GO:0004643; GO:0005829; GO:0005886; GO:0006139; GO:0006177; GO:0006189; GO:0009116; GO:0010035; GO:0016020; GO:0021549; GO:0021987; GO:0031100; GO:0042803; GO:0044208; GO:0045296; GO:0046452; GO:0046654; GO:0070062; GO:0097294; GO:0098761 11664 FUN_026982 4876 4068 2182 2869 1963 ptg000020l:15472250-15483293 P31939 4.34e-32 Bifunctional purine biosynthesis protein ATIC (AICAR transformylase/inosine monophosphate cyclohydrolase) (ATIC) [Cleaved into: Bifunctional purine biosynthesis protein ATIC, N-terminally processed] [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) (AICAR formyltransferase) (AICAR transformylase); Inosine 5'-monophosphate cyclohydrolase (IMP cyclohydrolase) (EC 3.5.4.10) (IMP synthase) (Inosinicase)] Homo sapiens (Human) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; animal organ regeneration [GO:0031100]; brainstem development [GO:0003360]; cellular response to interleukin-7 [GO:0098761]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; dihydrofolate metabolic process [GO:0046452]; GMP biosynthetic process [GO:0006177]; nucleobase-containing compound metabolic process [GO:0006139]; nucleoside metabolic process [GO:0009116]; response to inorganic substance [GO:0010035]; tetrahydrofolate biosynthetic process [GO:0046654] GO:0003360; GO:0003937; GO:0004643; GO:0005829; GO:0005886; GO:0006139; GO:0006177; GO:0006189; GO:0009116; GO:0010035; GO:0016020; GO:0021549; GO:0021987; GO:0031100; GO:0042803; GO:0044208; GO:0045296; GO:0046452; GO:0046654; GO:0070062; GO:0097294; GO:0098761 11665 FUN_008729 1238 609 726 1040 1159 ptg000002l:14881042-14901023 Q80TR8 3.9e-25 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 11666 FUN_008728 126 201 194 248 98 NA NA NA NA NA NA NA 11667 FUN_008721 0 25 0 10 38 NA NA NA NA NA NA NA 11668 FUN_008720 158 74 19 122 82 NA NA NA NA NA NA NA 11669 FUN_008723 6145 3925 7367 5396 3193 NA NA NA NA NA NA NA 11670 FUN_008722 1117 1099 767 1558 904 NA NA NA NA NA NA NA 11671 FUN_008725 1058 2118 800 1434 1104 NA NA NA NA NA NA NA 11672 FUN_008724 75 16 27 21 11 NA NA NA NA NA NA NA 11673 FUN_008727 4 0 4 11 27 NA NA NA NA NA NA NA 11674 FUN_008726 586 585 194 446 119 NA NA NA NA NA NA NA 11675 FUN_000538 8 1 8 50 14 NA NA NA NA NA NA NA 11676 FUN_000539 0 0 4 7 11 NA NA NA NA NA NA NA 11677 FUN_014858 1606 807 820 2418 805 NA NA NA NA NA NA NA 11678 FUN_014859 819 920 652 1007 1193 ptg000009l:3754815-3757623 O55192 8.9e-33 Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2) Mus musculus (Mouse) dopamine uptake involved in synaptic transmission [GO:0051583]; monoamine transport [GO:0015844]; neurotransmitter reuptake [GO:0098810]; neurotransmitter transport [GO:0006836]; norepinephrine transport [GO:0015874]; norepinephrine uptake [GO:0051620]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sodium ion transmembrane transport [GO:0035725] GO:0003779; GO:0005326; GO:0005328; GO:0005330; GO:0005334; GO:0005886; GO:0006836; GO:0008504; GO:0009410; GO:0009986; GO:0015844; GO:0015874; GO:0032809; GO:0035725; GO:0042734; GO:0043005; GO:0043014; GO:0045121; GO:0046872; GO:0048265; GO:0048487; GO:0051583; GO:0051620; GO:0098810 11679 FUN_000534 2538 1970 1233 1728 1627 NA NA NA NA NA NA NA 11680 FUN_000535 186 221 309 287 295 ntLink_6:4129074-4130763 Q9Z2D7 2.62e-25 Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; response to radiation [GO:0009314] GO:0000785; GO:0003677; GO:0005634; GO:0005737; GO:0006281; GO:0006306; GO:0006974; GO:0007095; GO:0008263; GO:0008630; GO:0009314; GO:0016607 11681 FUN_000535 186 221 309 287 295 ntLink_6:4129074-4130763 Q9Z2D7 1.62e-24 Methyl-CpG-binding domain protein 4 (EC 3.2.2.-) (Methyl-CpG-binding protein MBD4) (Mismatch-specific DNA N-glycosylase) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; response to radiation [GO:0009314] GO:0000785; GO:0003677; GO:0005634; GO:0005737; GO:0006281; GO:0006306; GO:0006974; GO:0007095; GO:0008263; GO:0008630; GO:0009314; GO:0016607 11682 FUN_000536 1757 840 686 1405 1074 NA NA NA NA NA NA NA 11683 FUN_000537 1582 1212 865 1667 966 ntLink_6:4155754-4169754 Q6DCD5 2.15e-42 Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 2) Xenopus laevis (African clawed frog) protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005783; GO:0016020; GO:0035269 11684 FUN_000537 1582 1212 865 1667 966 ntLink_6:4155754-4169754 Q6DCD5 1.89e-29 Protein O-mannosyl-transferase TMTC2 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 2) Xenopus laevis (African clawed frog) protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0004169; GO:0005783; GO:0016020; GO:0035269 11685 FUN_014852 1966 1629 1033 1551 1160 ptg000009l:3691609-3696389 Q8BVU5 1.23e-21 ADP-ribose pyrophosphatase, mitochondrial (EC 3.6.1.13) (ADP-ribose diphosphatase) (ADP-ribose phosphohydrolase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (Nucleoside diphosphate-linked moiety X motif 9) (Nudix motif 9) Mus musculus (Mouse) ADP catabolic process [GO:0046032]; IDP catabolic process [GO:0046709] GO:0005739; GO:0016604; GO:0030054; GO:0031965; GO:0046032; GO:0046709; GO:0047631 11686 FUN_000532 43 36 18 52 70 NA NA NA NA NA NA NA 11687 FUN_013807 70 7 0 0 0 NA NA NA NA NA NA NA 11688 FUN_044091 14 5 35 5 203 NA NA NA NA NA NA NA 11689 FUN_039277 26 15 9 9 34 NA NA NA NA NA NA NA 11690 FUN_039275 1156 639 180 646 389 ptg000028l:174174-182484 Q96AY4 9.64e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11691 FUN_039275 1156 639 180 646 389 ptg000028l:174174-182484 Q96AY4 2.4e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11692 FUN_039275 1156 639 180 646 389 ptg000028l:174174-182484 Q96AY4 3.03e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11693 FUN_039274 1316 603 455 633 792 NA NA NA NA NA NA NA 11694 FUN_039273 270 201 103 64 0 NA NA NA NA NA NA NA 11695 FUN_039272 113 301 74 122 146 ptg000028l:116149-120252 Q8K4H1 2.65e-66 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 11696 FUN_039272 113 301 74 122 146 ptg000028l:116149-120252 Q8K4H1 1.4e-60 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 11697 FUN_039271 576 327 102 292 198 ptg000028l:110855-113252 Q8K4H1 1.08e-63 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 11698 FUN_039270 32 60 136 153 120 NA NA NA NA NA NA NA 11699 FUN_039279 88 42 116 276 262 NA NA NA NA NA NA NA 11700 FUN_039278 34 8 0 23 41 NA NA NA NA NA NA NA 11701 FUN_000331 1739 1265 873 1010 748 NA NA NA NA NA NA NA 11702 FUN_010579 386 219 205 605 267 NA NA NA NA NA NA NA 11703 FUN_010570 12 0 4 0 2 NA NA NA NA NA NA NA 11704 FUN_010573 0 14 0 0 21 NA NA NA NA NA NA NA 11705 FUN_010572 0 0 15 12 0 NA NA NA NA NA NA NA 11706 FUN_040295 36 0 0 0 0 NA NA NA NA NA NA NA 11707 FUN_040294 77 10 26 217 14 ptg000031l:6539590-6540574 Q76DT2 1.02e-62 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 11708 FUN_010577 13 12 22 18 31 ptg000007l:350652-353867 Q96KE9 3.35e-53 BTB/POZ domain-containing protein 6 (Lens BTB domain protein) Homo sapiens (Human) neurogenesis [GO:0022008] GO:0005829; GO:0022008 11709 FUN_010576 3991 2629 1456 4683 2049 NA NA NA NA NA NA NA 11710 FUN_031046 0 0 0 10 0 NA NA NA NA NA NA NA 11711 FUN_017031 0 0 0 0 11 NA NA NA NA NA NA NA 11712 FUN_012042 384 643 427 1011 376 NA NA NA NA NA NA NA 11713 FUN_012041 872 647 692 1691 1133 ptg000008l:4477014-4484431 G3UYQ4 1.06e-30 NA NA NA NA 11714 FUN_012040 66 33 103 241 324 NA NA NA NA NA NA NA 11715 FUN_012046 1512 923 620 1010 1241 ptg000008l:4512472-4524157 P58501 7.9e-21 PAX3- and PAX7-binding protein 1 (PAX3/7BP) (GC-rich sequence DNA-binding factor 1) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; muscle organ development [GO:0007517]; positive regulation of histone methylation [GO:0031062]; positive regulation of myoblast proliferation [GO:2000288]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of skeletal muscle satellite cell proliferation [GO:0014842]; transcription by RNA polymerase II [GO:0006366] GO:0000398; GO:0003677; GO:0005634; GO:0006366; GO:0007517; GO:0014842; GO:0031062; GO:0045944; GO:1990226; GO:2000288 11716 FUN_012049 3682 2275 1967 4357 3441 ptg000008l:4529727-4567996 Q8C170 6.42e-34 Unconventional myosin-IXa (Unconventional myosin-9a) Mus musculus (Mouse) cell junction assembly [GO:0034329]; establishment of epithelial cell apical/basal polarity [GO:0045198]; intracellular signal transduction [GO:0035556]; positive regulation of GTPase activity [GO:0043547]; postsynaptic specialization organization [GO:0099084]; regulation of neuron projection arborization [GO:0150011] GO:0000146; GO:0005096; GO:0005524; GO:0005737; GO:0005884; GO:0016020; GO:0016459; GO:0034329; GO:0035556; GO:0043547; GO:0044295; GO:0045198; GO:0046872; GO:0051015; GO:0098685; GO:0098794; GO:0098978; GO:0099084; GO:0150011 11717 FUN_015891 0 0 3 0 6 NA NA NA NA NA NA NA 11718 FUN_020949 144 365 659 323 771 NA NA NA NA NA NA NA 11719 FUN_015895 187 0 8 0 45 NA NA NA NA NA NA NA 11720 FUN_015894 348 3 327 422 81 NA NA NA NA NA NA NA 11721 FUN_015897 0 4 36 9 43 NA NA NA NA NA NA NA 11722 FUN_015896 29 0 11 2 0 NA NA NA NA NA NA NA 11723 FUN_020943 0 0 33 9 181 NA NA NA NA NA NA NA 11724 FUN_015898 0 0 17 28 64 NA NA NA NA NA NA NA 11725 FUN_020947 0 0 12 0 2 NA NA NA NA NA NA NA 11726 FUN_020944 0 0 6 28 44 NA NA NA NA NA NA NA 11727 FUN_016150 1224 759 569 958 979 NA NA NA NA NA NA NA 11728 FUN_028476 232 2 20 20 65 NA NA NA NA NA NA NA 11729 FUN_028471 2356 1722 959 2827 2161 NA NA NA NA NA NA NA 11730 FUN_028470 2910 1865 1375 2493 1851 ptg000021l:20431664-20454776 Q17LW0 6.4e-35 Myosin-VIIa (Protein crinkled) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0007605; GO:0008407; GO:0016459; GO:0030048; GO:0032027; GO:0035317; GO:0048800; GO:0071944; GO:0120025 11731 FUN_028470 2910 1865 1375 2493 1851 ptg000021l:20431664-20454776 Q17LW0 2.14e-28 Myosin-VIIa (Protein crinkled) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0007605; GO:0008407; GO:0016459; GO:0030048; GO:0032027; GO:0035317; GO:0048800; GO:0071944; GO:0120025 11732 FUN_028470 2910 1865 1375 2493 1851 ptg000021l:20431664-20454776 Q17LW0 1.99e-27 Myosin-VIIa (Protein crinkled) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0007605; GO:0008407; GO:0016459; GO:0030048; GO:0032027; GO:0035317; GO:0048800; GO:0071944; GO:0120025 11733 FUN_028470 2910 1865 1375 2493 1851 ptg000021l:20431664-20454776 Q17LW0 3.12e-22 Myosin-VIIa (Protein crinkled) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) actin filament-based movement [GO:0030048]; antennal morphogenesis [GO:0048800]; chaeta morphogenesis [GO:0008407]; imaginal disc-derived wing hair organization [GO:0035317]; sensory perception of sound [GO:0007605] GO:0000146; GO:0003779; GO:0005524; GO:0005737; GO:0007605; GO:0008407; GO:0016459; GO:0030048; GO:0032027; GO:0035317; GO:0048800; GO:0071944; GO:0120025 11734 FUN_043998 0 0 11 0 0 NA NA NA NA NA NA NA 11735 FUN_014075 0 0 0 0 13 NA NA NA NA NA NA NA 11736 FUN_014076 0 0 0 0 12 NA NA NA NA NA NA NA 11737 FUN_001201 1171 2097 335 1014 600 ntLink_6:9717132-9724304 Q4R4S5 1.08e-27 Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) lipid catabolic process [GO:0016042] GO:0004771; GO:0005764; GO:0016042 11738 FUN_009443 0 37 0 0 0 NA NA NA NA NA NA NA 11739 FUN_009442 1627 1157 603 1175 833 NA NA NA NA NA NA NA 11740 FUN_009441 29692 37139 11307 11227 9658 NA NA NA NA NA NA NA 11741 FUN_009440 2247 1405 1688 1320 1057 NA NA NA NA NA NA NA 11742 FUN_009447 13 0 0 0 101 NA NA NA NA NA NA NA 11743 FUN_009446 0 0 0 58 21 NA NA NA NA NA NA NA 11744 FUN_009445 0 0 0 0 43 NA NA NA NA NA NA NA 11745 FUN_009444 33 25 2 20 0 NA NA NA NA NA NA NA 11746 FUN_009449 738 535 221 943 775 NA NA NA NA NA NA NA 11747 FUN_009448 0 0 4 31 80 NA NA NA NA NA NA NA 11748 FUN_001200 861 723 550 741 775 NA NA NA NA NA NA NA 11749 FUN_026453 81 347 9 909 529 NA NA NA NA NA NA NA 11750 FUN_026452 0 0 0 0 10 NA NA NA NA NA NA NA 11751 FUN_026451 3 10 0 75 33 NA NA NA NA NA NA NA 11752 FUN_026450 55 122 13 138 217 NA NA NA NA NA NA NA 11753 FUN_026457 19 0 0 60 0 NA NA NA NA NA NA NA 11754 FUN_026456 0 0 0 67 21 NA NA NA NA NA NA NA 11755 FUN_026455 8 1 0 88 136 NA NA NA NA NA NA NA 11756 FUN_026454 0 0 0 10 25 NA NA NA NA NA NA NA 11757 FUN_026458 28 2 41 11 201 NA NA NA NA NA NA NA 11758 FUN_039912 10 0 3 0 62 NA NA NA NA NA NA NA 11759 FUN_039913 20 3 0 0 0 NA NA NA NA NA NA NA 11760 FUN_039919 5 0 0 1428 0 NA NA NA NA NA NA NA 11761 FUN_022516 185 191 145 303 260 ptg000016l:9903652-9906829 Q8K3Z0 1.26e-38 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 11762 FUN_022517 1121 663 624 656 774 NA NA NA NA NA NA NA 11763 FUN_022514 10 0 0 0 0 NA NA NA NA NA NA NA 11764 FUN_022512 6532 3279 1596 4554 3553 NA NA NA NA NA NA NA 11765 FUN_022513 236 36 97 100 145 NA NA NA NA NA NA NA 11766 FUN_022510 38 0 5 15 4 NA NA NA NA NA NA NA 11767 FUN_022511 170 19 0 57 17 NA NA NA NA NA NA NA 11768 FUN_022518 7682 4216 4357 9507 6727 NA NA NA NA NA NA NA 11769 FUN_022519 1960 1629 1306 1838 1437 NA NA NA NA NA NA NA 11770 FUN_015309 0 0 0 10 0 NA NA NA NA NA NA NA 11771 FUN_015308 5889 2996 3578 5053 4579 NA NA NA NA NA NA NA 11772 FUN_015301 0 0 49 0 9 NA NA NA NA NA NA NA 11773 FUN_015300 2045 1257 1128 1783 1417 NA NA NA NA NA NA NA 11774 FUN_015303 2535 1808 1202 1947 2205 NA NA NA NA NA NA NA 11775 FUN_015302 0 0 0 18 0 NA NA NA NA NA NA NA 11776 FUN_015304 724 425 196 362 348 NA NA NA NA NA NA NA 11777 FUN_015307 496 226 321 651 736 NA NA NA NA NA NA NA 11778 FUN_015306 0 0 0 0 8 NA NA NA NA NA NA NA 11779 FUN_018562 6 0 1 0 6 NA NA NA NA NA NA NA 11780 FUN_018560 0 0 7 0 3 NA NA NA NA NA NA NA 11781 FUN_018561 97 0 37 78 60 NA NA NA NA NA NA NA 11782 FUN_017799 1591 4689 3010 2988 2431 NA NA NA NA NA NA NA 11783 FUN_018565 8 0 0 6 4 NA NA NA NA NA NA NA 11784 FUN_017794 294 177 192 438 386 NA NA NA NA NA NA NA 11785 FUN_017795 1022 552 798 1047 804 NA NA NA NA NA NA NA 11786 FUN_018568 0 0 0 8 2 NA NA NA NA NA NA NA 11787 FUN_017797 3483 297 178 3408 2465 NA NA NA NA NA NA NA 11788 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 1.3e-91 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11789 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 1.21e-85 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11790 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 5.65e-79 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11791 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 1.22e-76 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11792 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 8.28e-73 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11793 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 6.53e-66 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11794 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 1.06e-57 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11795 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 1.87e-43 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11796 FUN_017790 211 474 172 262 729 ptg000012l:492629-504317 P07207 2.71e-38 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 11797 FUN_017791 15 11 52 6 58 NA NA NA NA NA NA NA 11798 FUN_017792 29 51 0 77 99 NA NA NA NA NA NA NA 11799 FUN_017793 265 159 81 144 131 NA NA NA NA NA NA NA 11800 FUN_021155 0 0 0 0 18 NA NA NA NA NA NA NA 11801 FUN_021154 0 0 0 0 33 NA NA NA NA NA NA NA 11802 FUN_021153 0 0 8 0 0 NA NA NA NA NA NA NA 11803 FUN_021152 13 16 15 16 19 NA NA NA NA NA NA NA 11804 FUN_000207 232 90 85 82 321 NA NA NA NA NA NA NA 11805 FUN_017866 1004 717 542 847 509 NA NA NA NA NA NA NA 11806 FUN_017867 540 347 605 770 672 NA NA NA NA NA NA NA 11807 FUN_017864 2248 212 2049 1845 1464 ptg000012l:1248819-1319395 Q86TJ5 1.13e-39 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11808 FUN_017864 2248 212 2049 1845 1464 ptg000012l:1248819-1319395 Q86TJ5 5.17e-31 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11809 FUN_017864 2248 212 2049 1845 1464 ptg000012l:1248819-1319395 Q86TJ5 3.53e-27 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11810 FUN_017864 2248 212 2049 1845 1464 ptg000012l:1248819-1319395 Q86TJ5 1.01e-26 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11811 FUN_017865 168 26 110 139 133 NA NA NA NA NA NA NA 11812 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 1.72e-44 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11813 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 7.13e-44 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11814 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 7.37e-37 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11815 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 1.91e-35 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11816 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 8.37e-35 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11817 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 8.4e-32 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11818 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 1.99e-28 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11819 FUN_017862 1031 461 922 576 737 ptg000012l:1214365-1222022 Q86TJ5 7.62e-25 Zinc finger protein 554 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005654; GO:0005730; GO:0006357; GO:0046872 11820 FUN_017863 459 381 269 288 317 NA NA NA NA NA NA NA 11821 FUN_017860 396 331 167 236 124 NA NA NA NA NA NA NA 11822 FUN_017861 1642 667 1083 1707 1093 NA NA NA NA NA NA NA 11823 FUN_017868 574 259 2818 415 382 NA NA NA NA NA NA NA 11824 FUN_017869 551 254 330 623 363 NA NA NA NA NA NA NA 11825 FUN_030186 108 271 114 222 107 NA NA NA NA NA NA NA 11826 FUN_035355 840 505 867 279 1183 ptg000025l:6669570-6680304 Q9WYX8 2.22e-28 Uncharacterized protein TM_0508 Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) DNA recombination [GO:0006310]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261] GO:0000731; GO:0003677; GO:0005524; GO:0006261; GO:0006310; GO:0008047; GO:0009378; GO:0017116 11827 FUN_035356 63 741 19 161 91 ptg000025l:6684049-6694617 Q5REG4 8.8e-31 Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007219; GO:0016567; GO:0016740; GO:0046872 11828 FUN_035357 61 57 41 58 28 ptg000025l:6697830-6741113 Q5REG4 8.15e-27 Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007219; GO:0016567; GO:0016740; GO:0046872 11829 FUN_030182 1512 581 968 811 483 NA NA NA NA NA NA NA 11830 FUN_035351 860 612 340 229 513 ptg000025l:6625092-6630717 Q6XPZ3 6.52e-23 Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) Canis lupus familiaris (Dog) (Canis familiaris) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; lipid metabolic process [GO:0006629]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol metabolic process [GO:0046471]; phosphatidylserine metabolic process [GO:0006658] GO:0004622; GO:0005615; GO:0005654; GO:0005764; GO:0006629; GO:0006631; GO:0006650; GO:0006651; GO:0006658; GO:0006672; GO:0008270; GO:0008374; GO:0008970; GO:0016020; GO:0016411; GO:0034638; GO:0046338; GO:0046470; GO:0046471; GO:0047499; GO:0052739; GO:0052740; GO:0102545 11831 FUN_013821 2 3 7 4 3 NA NA NA NA NA NA NA 11832 FUN_035358 53 118 134 347 110 ptg000025l:6742359-6747147 Q5REG4 5.93e-31 Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007219; GO:0016567; GO:0016740; GO:0046872 11833 FUN_035359 508 947 696 611 859 ptg000025l:6751247-6762388 Q2EMV9 4.32e-41 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6) (Poly [ADP-ribose] polymerase 14) (PARP-14) Mus musculus (Mouse) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 11834 FUN_035359 508 947 696 611 859 ptg000025l:6751247-6762388 Q2EMV9 1.93e-32 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6) (Poly [ADP-ribose] polymerase 14) (PARP-14) Mus musculus (Mouse) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 11835 FUN_035359 508 947 696 611 859 ptg000025l:6751247-6762388 Q2EMV9 1.05e-30 Protein mono-ADP-ribosyltransferase PARP14 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 8) (ARTD8) (Collaborator of STAT6) (CoaSt6) (Poly [ADP-ribose] polymerase 14) (PARP-14) Mus musculus (Mouse) innate immune response [GO:0045087]; negative regulation of gene expression [GO:0010629]; negative regulation of type II interferon-mediated signaling pathway [GO:0060336]; negative regulation of tyrosine phosphorylation of STAT protein [GO:0042532]; positive regulation of interleukin-4-mediated signaling pathway [GO:1902216]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein poly-ADP-ribosylation [GO:0070212] GO:0003714; GO:0003950; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0010629; GO:0016779; GO:0019899; GO:0042531; GO:0042532; GO:0045087; GO:0060336; GO:0070212; GO:0070403; GO:1902216; GO:1990404 11836 FUN_030188 426 200 70 229 120 ptg000023l:10185961-10186432 Q92752 6.15e-34 Tenascin-R (TN-R) (Janusin) (Restrictin) Homo sapiens (Human) associative learning [GO:0008306]; axon extension involved in regeneration [GO:0048677]; axon guidance [GO:0007411]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005576; GO:0005615; GO:0007155; GO:0007158; GO:0007411; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0048677; GO:0048692; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098978 11837 FUN_030189 856 634 100 509 256 NA NA NA NA NA NA NA 11838 FUN_031859 199 64 462 106 175 ptg000023l:26117634-26123755 Q29513 1.46e-23 Glycine N-methyltransferase (EC 2.1.1.20) Oryctolagus cuniculus (Rabbit) methylation [GO:0032259]; S-adenosylmethionine metabolic process [GO:0046500] GO:0005542; GO:0005829; GO:0016594; GO:0017174; GO:0032259; GO:0046500 11839 FUN_031858 280 0 0 83 89 NA NA NA NA NA NA NA 11840 FUN_007815 2320 2068 1950 1578 2290 ptg000002l:5032790-5035494 Q9Y6A2 2.3e-35 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 11841 FUN_007815 2320 2068 1950 1578 2290 ptg000002l:5032790-5035494 Q9Y6A2 1.95e-24 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 11842 FUN_031853 201 129 85 51 152 NA NA NA NA NA NA NA 11843 FUN_031852 27218 42437 12184 17047 19217 NA NA NA NA NA NA NA 11844 FUN_031851 1200 1043 527 877 578 NA NA NA NA NA NA NA 11845 FUN_031850 628 366 520 625 819 NA NA NA NA NA NA NA 11846 FUN_031857 75 0 0 0 0 NA NA NA NA NA NA NA 11847 FUN_031856 2369 865 2170 796 1648 ptg000023l:26080844-26086739 P13255 2.35e-22 Glycine N-methyltransferase (EC 2.1.1.20) (Folate-binding protein) Rattus norvegicus (Rat) folic acid metabolic process [GO:0046655]; glycine metabolic process [GO:0006544]; glycogen metabolic process [GO:0005977]; methionine metabolic process [GO:0006555]; methylation [GO:0032259]; one-carbon metabolic process [GO:0006730]; protein homotetramerization [GO:0051289]; regulation of gluconeogenesis [GO:0006111]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethionine metabolic process [GO:0046500]; sarcosine metabolic process [GO:1901052] GO:0005542; GO:0005634; GO:0005829; GO:0005977; GO:0006111; GO:0006544; GO:0006555; GO:0006730; GO:0008757; GO:0016594; GO:0017174; GO:0032259; GO:0034708; GO:0042802; GO:0046498; GO:0046500; GO:0046655; GO:0051289; GO:0098603; GO:1901052; GO:1904047 11848 FUN_031855 97 34 26 22 7 NA NA NA NA NA NA NA 11849 FUN_031854 1599 1540 865 1093 546 NA NA NA NA NA NA NA 11850 FUN_011701 1810 1120 833 1242 1214 NA NA NA NA NA NA NA 11851 FUN_038668 29 0 0 0 17 NA NA NA NA NA NA NA 11852 FUN_038667 28 0 2 0 26 NA NA NA NA NA NA NA 11853 FUN_038665 51 42 9 44 52 ptg000027l:9951328-9959572 Q96AY4 2.12e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11854 FUN_038665 51 42 9 44 52 ptg000027l:9951328-9959572 Q96AY4 8.05e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11855 FUN_038665 51 42 9 44 52 ptg000027l:9951328-9959572 Q96AY4 9e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11856 FUN_038665 51 42 9 44 52 ptg000027l:9951328-9959572 Q96AY4 6.97e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11857 FUN_038664 0 14 0 0 14 NA NA NA NA NA NA NA 11858 FUN_038662 99 96 9 0 121 ptg000027l:9912815-9936294 Q5RCY5 8.96e-36 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 11859 FUN_038661 14 0 0 0 0 NA NA NA NA NA NA NA 11860 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 3.79e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11861 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 7.59e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11862 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 1.33e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11863 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 8.07e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11864 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 1.38e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11865 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 2.04e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11866 FUN_038660 116 68 158 94 134 ptg000027l:9893145-9900924 Q96AY4 5.28e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 11867 FUN_031589 1109 799 503 890 515 NA NA NA NA NA NA NA 11868 FUN_031588 710 618 382 554 671 NA NA NA NA NA NA NA 11869 FUN_031585 42 0 319 495 177 NA NA NA NA NA NA NA 11870 FUN_031584 0 32 0 41 33 NA NA NA NA NA NA NA 11871 FUN_031587 21 0 13 338 18 NA NA NA NA NA NA NA 11872 FUN_031586 27 65 90 312 395 NA NA NA NA NA NA NA 11873 FUN_031581 4 0 0 11 6 NA NA NA NA NA NA NA 11874 FUN_031580 0 0 15 0 0 NA NA NA NA NA NA NA 11875 FUN_031583 0 0 0 0 8 NA NA NA NA NA NA NA 11876 FUN_031582 31 0 10 0 0 NA NA NA NA NA NA NA 11877 FUN_030082 19 0 23 6 165 NA NA NA NA NA NA NA 11878 FUN_007343 3 0 0 1 6 NA NA NA NA NA NA NA 11879 FUN_001910 133 0 37 682 410 ntLink_6:17663360-17672263 Q96CG8 4.15e-26 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 11880 FUN_001912 43 87 74 34 6788 NA NA NA NA NA NA NA 11881 FUN_001914 0 0 4 0 18 NA NA NA NA NA NA NA 11882 FUN_001917 32 81 26 38 0 NA NA NA NA NA NA NA 11883 FUN_001918 5 0 0 0 7 NA NA NA NA NA NA NA 11884 FUN_013519 67 9 13 98 41 ptg000008l:23645611-23646787 P0C0R5 6.21e-38 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 11885 FUN_030451 9 0 8 1 36 ptg000023l:10894583-10895346 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11886 FUN_025631 65 0 62 3 139 NA NA NA NA NA NA NA 11887 FUN_030455 7 0 9 1 43 ptg000023l:10902686-10903449 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11888 FUN_030457 14 0 8 0 32 ptg000023l:10906738-10907501 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 11889 FUN_031329 0 0 0 0 87 NA NA NA NA NA NA NA 11890 FUN_036119 157 62 95 86 242 NA NA NA NA NA NA NA 11891 FUN_036118 445 162 201 298 204 NA NA NA NA NA NA NA 11892 FUN_036117 363 165 223 341 285 NA NA NA NA NA NA NA 11893 FUN_036116 977 1055 908 1230 2002 NA NA NA NA NA NA NA 11894 FUN_031323 18 15 20 0 14 ptg000023l:19585327-19598898 Q7RTR2 1.68e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11895 FUN_031323 18 15 20 0 14 ptg000023l:19585327-19598898 Q7RTR2 4.94e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11896 FUN_031323 18 15 20 0 14 ptg000023l:19585327-19598898 Q7RTR2 6.03e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11897 FUN_031323 18 15 20 0 14 ptg000023l:19585327-19598898 Q7RTR2 8.38e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11898 FUN_031323 18 15 20 0 14 ptg000023l:19585327-19598898 Q7RTR2 3.16e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11899 FUN_031322 174 42 68 0 42 ptg000023l:19492047-19585304 Q7RTR2 1.18e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11900 FUN_031322 174 42 68 0 42 ptg000023l:19492047-19585304 Q7RTR2 8.08e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11901 FUN_031322 174 42 68 0 42 ptg000023l:19492047-19585304 Q7RTR2 7.46e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11902 FUN_031322 174 42 68 0 42 ptg000023l:19492047-19585304 Q7RTR2 1.19e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11903 FUN_036110 1186 851 392 1063 729 ptg000025l:15480778-15486267 Q5E9W3 3e-24 Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) Bos taurus (Bovine) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] GO:0004152; GO:0005743; GO:0006207; GO:0009220; GO:0044205; GO:0106430 11904 FUN_036110 1186 851 392 1063 729 ptg000025l:15480778-15486267 Q5E9W3 1.58e-21 Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) Bos taurus (Bovine) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; 'de novo' UMP biosynthetic process [GO:0044205]; pyrimidine ribonucleotide biosynthetic process [GO:0009220] GO:0004152; GO:0005743; GO:0006207; GO:0009220; GO:0044205; GO:0106430 11905 FUN_037861 15 0 27 0 71 NA NA NA NA NA NA NA 11906 FUN_037862 4328 2595 2936 3837 3381 NA NA NA NA NA NA NA 11907 FUN_037863 14 54 0 0 0 NA NA NA NA NA NA NA 11908 FUN_037865 2623 2911 1221 2016 1507 NA NA NA NA NA NA NA 11909 FUN_037866 1295 1193 716 1028 619 NA NA NA NA NA NA NA 11910 FUN_037867 1740 923 865 1722 1069 ptg000026l:14530033-14539212 P59281 3.7e-25 Rho GTPase-activating protein 39 Mus musculus (Mouse) postsynapse organization [GO:0099173]; signal transduction [GO:0007165] GO:0005096; GO:0005634; GO:0005737; GO:0005856; GO:0007165; GO:0098794; GO:0098978; GO:0099173 11911 FUN_037868 0 0 0 0 31 NA NA NA NA NA NA NA 11912 FUN_037869 35 32 8 8 8 NA NA NA NA NA NA NA 11913 FUN_003636 6 0 0 0 0 NA NA NA NA NA NA NA 11914 FUN_024587 181 122 142 900 472 NA NA NA NA NA NA NA 11915 FUN_008175 0 61 0 19 93 NA NA NA NA NA NA NA 11916 FUN_024585 661 155 305 670 319 NA NA NA NA NA NA NA 11917 FUN_024584 251 85 202 111 70 NA NA NA NA NA NA NA 11918 FUN_005950 980 912 302 273 1043 NA NA NA NA NA NA NA 11919 FUN_024583 345 401 221 536 419 NA NA NA NA NA NA NA 11920 FUN_003637 19 0 22 8 0 NA NA NA NA NA NA NA 11921 FUN_024582 0 13 3 31 21 NA NA NA NA NA NA NA 11922 FUN_040005 41 0 67 0 79 NA NA NA NA NA NA NA 11923 FUN_029481 35 18 84 23 284 NA NA NA NA NA NA NA 11924 FUN_024581 273 293 164 602 344 NA NA NA NA NA NA NA 11925 FUN_008173 141 0 0 0 0 NA NA NA NA NA NA NA 11926 FUN_029482 0 13 16 0 0 NA NA NA NA NA NA NA 11927 FUN_040611 193 231 43 216 175 NA NA NA NA NA NA NA 11928 FUN_027269 7 21 2931 14 198 NA NA NA NA NA NA NA 11929 FUN_027268 0 12 207 0 0 NA NA NA NA NA NA NA 11930 FUN_027267 0 16 28 0 78 NA NA NA NA NA NA NA 11931 FUN_027266 0 0 23 0 38 NA NA NA NA NA NA NA 11932 FUN_027265 0 43 0 0 29 NA NA NA NA NA NA NA 11933 FUN_027264 55 15 62 13 18 NA NA NA NA NA NA NA 11934 FUN_027262 914 715 205 62 385 NA NA NA NA NA NA NA 11935 FUN_027261 28 17 0 42 32 NA NA NA NA NA NA NA 11936 FUN_027260 536 469 512 745 453 NA NA NA NA NA NA NA 11937 FUN_005958 12313 17519 6031 2910 3308 NA NA NA NA NA NA NA 11938 FUN_044108 41 179 74 131 383 NA NA NA NA NA NA NA 11939 FUN_044253 0 9 16 7 38 NA NA NA NA NA NA NA 11940 FUN_014265 4104 4186 3466 3060 2209 ptg000008l:34261219-34261771 P61227 1.18e-82 Ras-related protein Rap-2b (EC 3.6.5.2) Rattus norvegicus (Rat) negative regulation of cell migration [GO:0030336]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of protein autophosphorylation [GO:0031954]; Rap protein signal transduction [GO:0032486]; regulation of protein tyrosine kinase activity [GO:0061097] GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0005923; GO:0016020; GO:0019003; GO:0019904; GO:0030168; GO:0030336; GO:0031954; GO:0032486; GO:0044291; GO:0045121; GO:0055037; GO:0055038; GO:0061097; GO:0070062; GO:0070527 11941 FUN_026371 59 2239 584 85 1109 NA NA NA NA NA NA NA 11942 FUN_037249 0 10 6 7 0 NA NA NA NA NA NA NA 11943 FUN_044104 6 7 15 2 123 NA NA NA NA NA NA NA 11944 FUN_037244 16990 13946 79 6414 60 NA NA NA NA NA NA NA 11945 FUN_037245 0 0 0 26 0 NA NA NA NA NA NA NA 11946 FUN_037247 279 142 104 91 5 NA NA NA NA NA NA NA 11947 FUN_037240 1116 789 497 1098 727 NA NA NA NA NA NA NA 11948 FUN_014266 9 0 0 0 0 NA NA NA NA NA NA NA 11949 FUN_044252 2 6 9 10 26 NA NA NA NA NA NA NA 11950 FUN_026375 5505 4515 2939 4855 3585 NA NA NA NA NA NA NA 11951 FUN_044100 3 3 7 0 36 NA NA NA NA NA NA NA 11952 FUN_005340 69 49 54 94 72 NA NA NA NA NA NA NA 11953 FUN_005341 1212 497 597 2382 3072 NA NA NA NA NA NA NA 11954 FUN_005343 60508 54318 23384 36253 27144 NA NA NA NA NA NA NA 11955 FUN_044103 47 77 96 131 309 NA NA NA NA NA NA NA 11956 FUN_005346 89 23 32 81 174 NA NA NA NA NA NA NA 11957 FUN_005347 701 905 1054 2049 1410 NA NA NA NA NA NA NA 11958 FUN_005348 2379 1926 1389 3420 2153 NA NA NA NA NA NA NA 11959 FUN_005349 2031 2331 1615 2196 1194 NA NA NA NA NA NA NA 11960 FUN_014262 1930 905 788 328 460 NA NA NA NA NA NA NA 11961 FUN_004431 1016 980 588 459 705 ntLink_8:23179623-23186501 Q7ZW46 3.82e-28 UDP-xylose and UDP-N-acetylglucosamine transporter (Solute carrier family 35 member B4) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate transport [GO:0008643] GO:0000139; GO:0005462; GO:0005464; GO:0005789; GO:0008643; GO:0022857 11962 FUN_004430 59 25 48 52 105 NA NA NA NA NA NA NA 11963 FUN_004433 6806 6029 3580 3563 3316 NA NA NA NA NA NA NA 11964 FUN_004432 1542 1380 926 1368 1051 ntLink_8:23187024-23190853 Q9Y2D2 2.99e-26 UDP-N-acetylglucosamine transporter (Golgi UDP-GlcNAc transporter) (Solute carrier family 35 member A3) Homo sapiens (Human) carbohydrate transport [GO:0008643]; UDP-N-acetylglucosamine metabolic process [GO:0006047]; UDP-N-acetylglucosamine transmembrane transport [GO:1990569] GO:0000139; GO:0005459; GO:0005462; GO:0005794; GO:0006047; GO:0008643; GO:1990569 11965 FUN_004435 1066 433 521 905 568 NA NA NA NA NA NA NA 11966 FUN_004437 2805 2449 1653 2056 1798 NA NA NA NA NA NA NA 11967 FUN_004436 1575 1016 933 1210 990 ntLink_8:23220936-23230056 Q8BW72 2.76e-55 Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A) Mus musculus (Mouse) cardiac muscle hypertrophy in response to stress [GO:0014898]; chromatin remodeling [GO:0006338]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; response to nutrient levels [GO:0031667] GO:0001650; GO:0005634; GO:0005654; GO:0005721; GO:0005737; GO:0005829; GO:0006338; GO:0008270; GO:0010507; GO:0010628; GO:0010629; GO:0014898; GO:0031625; GO:0031667; GO:0032452; GO:0032454; GO:0035064; GO:0045666; GO:0045892; GO:0048712; GO:0051864; GO:0060548; GO:0140681; GO:0140684 11968 FUN_004436 1575 1016 933 1210 990 ntLink_8:23220936-23230056 Q8BW72 2.76e-55 Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A) Mus musculus (Mouse) cardiac muscle hypertrophy in response to stress [GO:0014898]; chromatin remodeling [GO:0006338]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; response to nutrient levels [GO:0031667] GO:0001650; GO:0005634; GO:0005654; GO:0005721; GO:0005737; GO:0005829; GO:0006338; GO:0008270; GO:0010507; GO:0010628; GO:0010629; GO:0014898; GO:0031625; GO:0031667; GO:0032452; GO:0032454; GO:0035064; GO:0045666; GO:0045892; GO:0048712; GO:0051864; GO:0060548; GO:0140681; GO:0140684 11969 FUN_004436 1575 1016 933 1210 990 ntLink_8:23220936-23230056 Q8BW72 2.76e-55 Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A) Mus musculus (Mouse) cardiac muscle hypertrophy in response to stress [GO:0014898]; chromatin remodeling [GO:0006338]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of autophagy [GO:0010507]; negative regulation of cell death [GO:0060548]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; response to nutrient levels [GO:0031667] GO:0001650; GO:0005634; GO:0005654; GO:0005721; GO:0005737; GO:0005829; GO:0006338; GO:0008270; GO:0010507; GO:0010628; GO:0010629; GO:0014898; GO:0031625; GO:0031667; GO:0032452; GO:0032454; GO:0035064; GO:0045666; GO:0045892; GO:0048712; GO:0051864; GO:0060548; GO:0140681; GO:0140684 11970 FUN_004439 387 231 225 358 320 NA NA NA NA NA NA NA 11971 FUN_004438 194 125 100 180 179 NA NA NA NA NA NA NA 11972 FUN_018338 71 12 93 357 81 NA NA NA NA NA NA NA 11973 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 4.96e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11974 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 5.79e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11975 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 1.16e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11976 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 3.36e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11977 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 1.15e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11978 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 3.13e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11979 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 3.91e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11980 FUN_006491 625 416 56 977 806 ptg000001l:13152667-13223215 Q7RTR2 1.82e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11981 FUN_006490 49 11 40 6 6 NA NA NA NA NA NA NA 11982 FUN_006492 686 0 1331 149 12 ptg000001l:13249399-13257781 Q7RTR2 2.3e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11983 FUN_006492 686 0 1331 149 12 ptg000001l:13249399-13257781 Q7RTR2 9.41e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 11984 FUN_006494 230 318 267 2062 470 NA NA NA NA NA NA NA 11985 FUN_032748 817 647 437 314 601 ptg000023l:35560010-35568181 Q9UKV8 3.95e-70 Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer) Homo sapiens (Human) miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of amyloid precursor protein biosynthetic process [GO:0042985]; negative regulation of translational initiation [GO:0045947]; positive regulation of angiogenesis [GO:0045766]; positive regulation of gene expression [GO:0010628]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of trophoblast cell migration [GO:1901165]; post-embryonic development [GO:0009791]; pre-miRNA processing [GO:0031054]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501]; RNA-mediated gene silencing [GO:0031047]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422]; siRNA-mediated gene silencing by mRNA destabilization [GO:0090625]; translation [GO:0006412] GO:0000340; GO:0000932; GO:0000993; GO:0001046; GO:0003723; GO:0003725; GO:0003727; GO:0003743; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005844; GO:0005845; GO:0006412; GO:0008022; GO:0009791; GO:0010501; GO:0010586; GO:0010628; GO:0016020; GO:0016442; GO:0030422; GO:0030425; GO:0031047; GO:0031054; GO:0035194; GO:0035196; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0036464; GO:0042985; GO:0045766; GO:0045944; GO:0045947; GO:0046872; GO:0060213; GO:0070062; GO:0070551; GO:0070578; GO:0070922; GO:0090624; GO:0090625; GO:0098808; GO:1900153; GO:1901165; GO:1990904 11986 FUN_006496 0 10 0 0 0 NA NA NA NA NA NA NA 11987 FUN_032747 1538 327 449 1113 1324 ptg000023l:35540269-35555892 Q6QME8 8.79e-85 Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) Bos taurus (Bovine) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of translational initiation [GO:0045947]; pre-miRNA processing [GO:0031054]; regulation of DNA-templated transcription [GO:0006355] GO:0000340; GO:0000932; GO:0005634; GO:0005844; GO:0005845; GO:0006355; GO:0016442; GO:0031054; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0045947; GO:0046872; GO:0070551; GO:0070578; GO:1990904 11988 FUN_032747 1538 327 449 1113 1324 ptg000023l:35540269-35555892 Q6QME8 5.21e-23 Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) Bos taurus (Bovine) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of translational initiation [GO:0045947]; pre-miRNA processing [GO:0031054]; regulation of DNA-templated transcription [GO:0006355] GO:0000340; GO:0000932; GO:0005634; GO:0005844; GO:0005845; GO:0006355; GO:0016442; GO:0031054; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0045947; GO:0046872; GO:0070551; GO:0070578; GO:1990904 11989 FUN_032745 140 88 97 224 459 NA NA NA NA NA NA NA 11990 FUN_032742 67 3 233 45 24 NA NA NA NA NA NA NA 11991 FUN_032743 0 0 0 1 56 NA NA NA NA NA NA NA 11992 FUN_032740 4 0 2 3 115 NA NA NA NA NA NA NA 11993 FUN_004736 4854 4387 2864 4003 2932 NA NA NA NA NA NA NA 11994 FUN_030083 13 15 11 9 17 NA NA NA NA NA NA NA 11995 FUN_004737 3952 3302 3210 4117 2135 ntLink_8:26362923-26386308 P41413 2.21e-28 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 11996 FUN_004737 3952 3302 3210 4117 2135 ntLink_8:26362923-26386308 P41413 1.78e-27 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 11997 FUN_004737 3952 3302 3210 4117 2135 ntLink_8:26362923-26386308 P41413 4.14e-25 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 11998 FUN_004737 3952 3302 3210 4117 2135 ntLink_8:26362923-26386308 P41413 1.42e-24 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 11999 FUN_004737 3952 3302 3210 4117 2135 ntLink_8:26362923-26386308 P41413 3.85e-21 Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (Subtilisin/kexin-like protease PC5) (rPC5) Rattus norvegicus (Rat) anterior/posterior pattern specification [GO:0009952]; cardiac septum development [GO:0003279]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; coronary vasculature development [GO:0060976]; cytokine precursor processing [GO:0140447]; determination of left/right symmetry [GO:0007368]; embryo implantation [GO:0007566]; embryonic digestive tract development [GO:0048566]; embryonic skeletal system development [GO:0048706]; heart development [GO:0007507]; kidney development [GO:0001822]; limb morphogenesis [GO:0035108]; peptide biosynthetic process [GO:0043043]; peptide hormone processing [GO:0016486]; positive regulation of integrin activation [GO:0033625]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of smooth muscle cell-matrix adhesion [GO:1905609]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; protein processing [GO:0016485]; renin secretion into blood stream [GO:0002001]; respiratory tube development [GO:0030323]; response to gonadotropin [GO:0034698]; response to luteinizing hormone [GO:0034699]; signal peptide processing [GO:0006465]; vascular associated smooth muscle cell proliferation [GO:1990874]; viral life cycle [GO:0019058] GO:0000139; GO:0001822; GO:0002001; GO:0003279; GO:0004175; GO:0004252; GO:0005615; GO:0005794; GO:0005797; GO:0005802; GO:0005886; GO:0006465; GO:0007368; GO:0007507; GO:0007566; GO:0008233; GO:0009952; GO:0016020; GO:0016485; GO:0016486; GO:0019058; GO:0030323; GO:0033625; GO:0034698; GO:0034699; GO:0035108; GO:0036120; GO:0042277; GO:0043043; GO:0043204; GO:0048566; GO:0048706; GO:0060976; GO:0140447; GO:1904754; GO:1905609; GO:1990635; GO:1990874; GO:2001046 12000 FUN_034740 0 0 21 0 0 ptg000024l:11059422-11061379 Q09575 2.05e-29 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 12001 FUN_034744 0 0 0 2 57 NA NA NA NA NA NA NA 12002 FUN_034746 0 0 0 21 0 NA NA NA NA NA NA NA 12003 FUN_034747 0 14 0 9 0 NA NA NA NA NA NA NA 12004 FUN_034748 0 14 0 24 33 NA NA NA NA NA NA NA 12005 FUN_034749 3 0 0 0 41 NA NA NA NA NA NA NA 12006 FUN_020969 4 0 0 7 73 NA NA NA NA NA NA NA 12007 FUN_002774 1148 498 425 909 651 NA NA NA NA NA NA NA 12008 FUN_002775 0 0 0 0 38 NA NA NA NA NA NA NA 12009 FUN_002770 34 14 61 15 8 NA NA NA NA NA NA NA 12010 FUN_002773 0 0 0 0 12 NA NA NA NA NA NA NA 12011 FUN_040369 13 42 0 8 52 NA NA NA NA NA NA NA 12012 FUN_001146 67 67 115 209 99 NA NA NA NA NA NA NA 12013 FUN_001147 340 145 428 375 326 ntLink_6:9141532-9145634 Q6GQ29 2.05e-67 Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase) Xenopus laevis (African clawed frog) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0005737; GO:0005764; GO:0005783; GO:0005794; GO:0006508; GO:0042803; GO:0043171; GO:0046872; GO:0070573 12014 FUN_001147 340 145 428 375 326 ntLink_6:9141532-9145634 Q6GQ29 4.45e-29 Carboxypeptidase Q (EC 3.4.17.-) (Plasma glutamate carboxypeptidase) Xenopus laevis (African clawed frog) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0005737; GO:0005764; GO:0005783; GO:0005794; GO:0006508; GO:0042803; GO:0043171; GO:0046872; GO:0070573 12015 FUN_001144 3306 1953 1545 2540 1079 NA NA NA NA NA NA NA 12016 FUN_001145 1070 664 609 493 934 NA NA NA NA NA NA NA 12017 FUN_001142 14175 33802 19539 27996 16346 ntLink_6:9111644-9113966 Q45T69 6.97e-28 Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W) Canis lupus familiaris (Dog) (Canis familiaris) extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243] GO:0005634; GO:0005741; GO:0008630; GO:0016607; GO:0042803; GO:0046982; GO:0097192; GO:2001243 12018 FUN_001143 393 272 245 424 253 NA NA NA NA NA NA NA 12019 FUN_001140 1580 710 811 1721 1474 NA NA NA NA NA NA NA 12020 FUN_001141 1890 955 799 1161 1826 ntLink_6:9084454-9095030 Q8WML3 3.34e-32 Histone acetyltransferase KAT6B (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) histone acetylation [GO:0016573]; negative regulation of DNA-templated transcription [GO:0045892]; nucleosome assembly [GO:0006334]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000786; GO:0003677; GO:0003713; GO:0004402; GO:0005634; GO:0006334; GO:0016573; GO:0045892; GO:0045893; GO:0046872; GO:0061733; GO:0070776 12021 FUN_001148 3124 2302 2720 2931 2639 NA NA NA NA NA NA NA 12022 FUN_001149 4708 3084 2919 3712 2333 NA NA NA NA NA NA NA 12023 FUN_002489 207 189 130 21 1 NA NA NA NA NA NA NA 12024 FUN_002484 412 460 227 945 244 NA NA NA NA NA NA NA 12025 FUN_002480 1424 10 459 188 0 NA NA NA NA NA NA NA 12026 FUN_002481 950 917 1469 495 225 NA NA NA NA NA NA NA 12027 FUN_000439 215 184 88 228 178 NA NA NA NA NA NA NA 12028 FUN_000438 26 0 0 0 0 NA NA NA NA NA NA NA 12029 FUN_000435 32 5 14 15 0 NA NA NA NA NA NA NA 12030 FUN_000434 12 4 0 25 0 NA NA NA NA NA NA NA 12031 FUN_000437 947 1272 693 1041 1218 NA NA NA NA NA NA NA 12032 FUN_000436 414 661 371 261 134 NA NA NA NA NA NA NA 12033 FUN_000431 0 4 0 18 0 NA NA NA NA NA NA NA 12034 FUN_000430 7 136 72 372 0 NA NA NA NA NA NA NA 12035 FUN_000432 1317 1125 559 2241 11 ntLink_6:2968883-2971063 A0A1D5NSM8 1.53e-22 NA NA NA NA 12036 FUN_035831 716 336 357 760 429 NA NA NA NA NA NA NA 12037 FUN_035830 1061 704 821 946 693 NA NA NA NA NA NA NA 12038 FUN_035833 8690 5989 3932 8562 5201 NA NA NA NA NA NA NA 12039 FUN_035832 12 35 13 161 40 NA NA NA NA NA NA NA 12040 FUN_035835 0 29 39 0 9 NA NA NA NA NA NA NA 12041 FUN_035837 41 32 28 13 55 NA NA NA NA NA NA NA 12042 FUN_035836 76 122 19 88 44 NA NA NA NA NA NA NA 12043 FUN_035839 722 888 566 4161 2491 NA NA NA NA NA NA NA 12044 FUN_035838 1040 665 410 2464 1848 NA NA NA NA NA NA NA 12045 FUN_029320 90 40 53 24 42 NA NA NA NA NA NA NA 12046 FUN_029321 201 913 77 141 290 NA NA NA NA NA NA NA 12047 FUN_029322 0 501 195 0 53 NA NA NA NA NA NA NA 12048 FUN_029323 24 1635 1296 1029 360 NA NA NA NA NA NA NA 12049 FUN_029324 21 0 0 7 22 ptg000023l:514871-515738 Q90WN4 5.2e-56 Forkhead box protein D2 (FoxD2) (xFoxD2) (Fork head domain-related protein 9) (xFD-9) (Forkhead protein 3) (FKH-3) (xFKH3) Xenopus laevis (African clawed frog) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0043565 12050 FUN_029325 0 0 0 11 15 ptg000023l:519663-520953 Q63245 4.52e-28 Forkhead box protein D3 (HNF3/FH transcription factor genesis) (Hepatocyte nuclear factor 3 forkhead homolog 2) (HFH-2) Rattus norvegicus (Rat) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; cellular response to leukemia inhibitory factor [GO:1990830]; embryonic placenta development [GO:0001892]; in utero embryonic development [GO:0001701]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001701; GO:0001829; GO:0001892; GO:0003677; GO:0003690; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0009653; GO:0030154; GO:0045944; GO:1990830; GO:1990837 12051 FUN_029326 937 786 540 1098 951 NA NA NA NA NA NA NA 12052 FUN_029327 1662 1606 890 3318 1740 NA NA NA NA NA NA NA 12053 FUN_029328 1439 1473 528 1391 987 NA NA NA NA NA NA NA 12054 FUN_029329 3 0 0 28 13 NA NA NA NA NA NA NA 12055 FUN_040365 18 60 0 0 15 NA NA NA NA NA NA NA 12056 FUN_040901 611 2333 252 750 379 ptg000031l:13981515-14018469 Q8I7P9 2.47e-42 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 12057 FUN_040900 0 9 7 0 155 NA NA NA NA NA NA NA 12058 FUN_040903 4 17 7 63 29 NA NA NA NA NA NA NA 12059 FUN_040905 0 11 29 24 29 ptg000031l:14026984-14031587 Q9NBX4 8.45e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 12060 FUN_040905 0 11 29 24 29 ptg000031l:14026984-14031587 Q9NBX4 8.45e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 12061 FUN_040905 0 11 29 24 29 ptg000031l:14026984-14031587 Q9NBX4 8.45e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 12062 FUN_040904 10 7 31 80 96 NA NA NA NA NA NA NA 12063 FUN_040906 6 0 1 0 1 NA NA NA NA NA NA NA 12064 FUN_040909 0 0 8 0 0 NA NA NA NA NA NA NA 12065 FUN_040908 0 0 17 0 7 NA NA NA NA NA NA NA 12066 FUN_012539 0 0 0 6 5 NA NA NA NA NA NA NA 12067 FUN_012538 95 0 21 149 82 NA NA NA NA NA NA NA 12068 FUN_012533 688 1064 499 958 67 NA NA NA NA NA NA NA 12069 FUN_012532 56 99 67 197 116 NA NA NA NA NA NA NA 12070 FUN_012531 20532 13628 10492 25489 23947 ptg000008l:9676622-9690916 P26042 2.04e-22 Moesin (Membrane-organizing extension spike protein) Sus scrofa (Pig) immunological synapse formation [GO:0001771]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098] GO:0001771; GO:0003779; GO:0005737; GO:0005856; GO:0005886; GO:0005902; GO:0005912; GO:0008360; GO:0016324; GO:0030175; GO:0031528; GO:0042098; GO:0045177; GO:0050839; GO:0070489; GO:0072678; GO:1902115; GO:1902966; GO:2000643 12071 FUN_012531 20532 13628 10492 25489 23947 ptg000008l:9676622-9690916 P26042 2.04e-22 Moesin (Membrane-organizing extension spike protein) Sus scrofa (Pig) immunological synapse formation [GO:0001771]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of protein localization to early endosome [GO:1902966]; regulation of cell shape [GO:0008360]; regulation of organelle assembly [GO:1902115]; T cell aggregation [GO:0070489]; T cell migration [GO:0072678]; T cell proliferation [GO:0042098] GO:0001771; GO:0003779; GO:0005737; GO:0005856; GO:0005886; GO:0005902; GO:0005912; GO:0008360; GO:0016324; GO:0030175; GO:0031528; GO:0042098; GO:0045177; GO:0050839; GO:0070489; GO:0072678; GO:1902115; GO:1902966; GO:2000643 12072 FUN_012530 5572 4483 2112 5984 5158 ptg000008l:9665370-9674365 F1QGW6 1.09e-41 Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma) Danio rerio (Zebrafish) (Brachydanio rerio) formation of translation preinitiation complex [GO:0001731] GO:0000049; GO:0001731; GO:0003743; GO:0003924; GO:0005525; GO:0005850 12073 FUN_012530 5572 4483 2112 5984 5158 ptg000008l:9665370-9674365 F1QGW6 5.7e-22 Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma) (eIF-2-gamma) Danio rerio (Zebrafish) (Brachydanio rerio) formation of translation preinitiation complex [GO:0001731] GO:0000049; GO:0001731; GO:0003743; GO:0003924; GO:0005525; GO:0005850 12074 FUN_012537 89 99 65 87 93 NA NA NA NA NA NA NA 12075 FUN_012536 564 567 354 245 287 NA NA NA NA NA NA NA 12076 FUN_012535 615 761 503 717 697 NA NA NA NA NA NA NA 12077 FUN_012534 9532 13396 8446 8575 7544 NA NA NA NA NA NA NA 12078 FUN_016223 491 399 326 1129 1320 NA NA NA NA NA NA NA 12079 FUN_016222 8 0 10 0 17 NA NA NA NA NA NA NA 12080 FUN_016221 29 38 15 0 4 NA NA NA NA NA NA NA 12081 FUN_016220 67 2 12 0 18 NA NA NA NA NA NA NA 12082 FUN_016224 36 25 22 23 46 NA NA NA NA NA NA NA 12083 FUN_003163 20662 17778 8924 13653 9265 NA NA NA NA NA NA NA 12084 FUN_003166 2360 1556 1290 2075 1440 NA NA NA NA NA NA NA 12085 FUN_003167 22 4 11 7 113 NA NA NA NA NA NA NA 12086 FUN_003164 1033 1067 663 691 514 NA NA NA NA NA NA NA 12087 FUN_003165 6949 3814 2212 3569 1876 ntLink_8:8344824-8346546 Q5U4C9 0 Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) Mus musculus (Mouse) intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of glycogen biosynthetic process [GO:0045725]; protein phosphorylation [GO:0006468]; smoothened signaling pathway [GO:0007224] GO:0000151; GO:0000287; GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0006468; GO:0007224; GO:0018105; GO:0018107; GO:0018108; GO:0030145; GO:0042771; GO:0045725; GO:0070885; GO:0106310; GO:1990904 12088 FUN_003169 1046 329 316 907 280 NA NA NA NA NA NA NA 12089 FUN_023007 900 713 583 1066 1166 NA NA NA NA NA NA NA 12090 FUN_023006 3802 2435 1748 3168 2283 ptg000017l:2574737-2587946 Q9Y297 1.93e-24 F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit) Homo sapiens (Human) branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0000209; GO:0005654; GO:0005829; GO:0006470; GO:0006511; GO:0007165; GO:0008013; GO:0016055; GO:0016567; GO:0016874; GO:0019005; GO:0031146; GO:0031648; GO:0033598; GO:0042752; GO:0042753; GO:0043122; GO:0043161; GO:0043433; GO:0045309; GO:0045862; GO:0045879; GO:0045892; GO:0045893; GO:0046983; GO:0048511; GO:0051726; GO:0060444; GO:0060828; GO:0061136; GO:0061630; GO:0070936; GO:0071407; GO:1904668; GO:1990756; GO:1990757 12091 FUN_023006 3802 2435 1748 3168 2283 ptg000017l:2574737-2587946 Q9Y297 2.3e-21 F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit) Homo sapiens (Human) branching involved in mammary gland duct morphogenesis [GO:0060444]; cellular response to organic cyclic compound [GO:0071407]; mammary gland epithelial cell proliferation [GO:0033598]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of proteolysis [GO:0045862]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein destabilization [GO:0031648]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of cell cycle [GO:0051726]; regulation of circadian rhythm [GO:0042752]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of proteasomal protein catabolic process [GO:0061136]; rhythmic process [GO:0048511]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; signal transduction [GO:0007165]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0000209; GO:0005654; GO:0005829; GO:0006470; GO:0006511; GO:0007165; GO:0008013; GO:0016055; GO:0016567; GO:0016874; GO:0019005; GO:0031146; GO:0031648; GO:0033598; GO:0042752; GO:0042753; GO:0043122; GO:0043161; GO:0043433; GO:0045309; GO:0045862; GO:0045879; GO:0045892; GO:0045893; GO:0046983; GO:0048511; GO:0051726; GO:0060444; GO:0060828; GO:0061136; GO:0061630; GO:0070936; GO:0071407; GO:1904668; GO:1990756; GO:1990757 12092 FUN_028053 93 18 34 112 6 NA NA NA NA NA NA NA 12093 FUN_023004 50 53 75 133 125 NA NA NA NA NA NA NA 12094 FUN_028055 0 3 20 75 16 NA NA NA NA NA NA NA 12095 FUN_028056 49 27 9 63 52 NA NA NA NA NA NA NA 12096 FUN_036870 0 0 29 0 6 NA NA NA NA NA NA NA 12097 FUN_023140 8156 10107 3956 5300 5361 NA NA NA NA NA NA NA 12098 FUN_036872 2832 1213 2615 3178 4198 NA NA NA NA NA NA NA 12099 FUN_036873 8 0 55 35 68 NA NA NA NA NA NA NA 12100 FUN_036874 8 8 4 62 2 NA NA NA NA NA NA NA 12101 FUN_036875 10 13 0 0 14 NA NA NA NA NA NA NA 12102 FUN_036876 5291 2603 4355 15501 15161 ptg000026l:2891264-2938585 P14381 1.05e-111 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 12103 FUN_023008 697 532 142 495 524 NA NA NA NA NA NA NA 12104 FUN_033324 0 0 69 0 0 NA NA NA NA NA NA NA 12105 FUN_028588 28 7 5 37 37 NA NA NA NA NA NA NA 12106 FUN_040363 0 0 0 0 29 NA NA NA NA NA NA NA 12107 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.13e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12108 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.13e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12109 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.13e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12110 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.99e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12111 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.99e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12112 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.99e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12113 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.58e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12114 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.58e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12115 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.58e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12116 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.48e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12117 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.48e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12118 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.48e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12119 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.93e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12120 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.93e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12121 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.58e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12122 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 2.58e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12123 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.47e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12124 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.47e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12125 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.47e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12126 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.08e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12127 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.08e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12128 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.37e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12129 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.37e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12130 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.7e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12131 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.7e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12132 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 7.71e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12133 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 7.71e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12134 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 1.29e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12135 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 3.51e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12136 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 3.51e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12137 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.18e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12138 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 4.18e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12139 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 5.32e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12140 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 5.32e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12141 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 6.41e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12142 FUN_028583 0 0 0 0 11 ptg000022l:1078101-1080498 Q96AY4 6.41e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12143 FUN_028581 0 0 0 0 17 NA NA NA NA NA NA NA 12144 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 1.09e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12145 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 4.88e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12146 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 2.76e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12147 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 6.11e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12148 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 4.96e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12149 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 6.68e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12150 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 4.19e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12151 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 2.67e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12152 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 1.47e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12153 FUN_028587 53 0 0 0 82 ptg000022l:1150789-1152019 Q96AY4 1.01e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12154 FUN_028586 6 33 25 11 29 NA NA NA NA NA NA NA 12155 FUN_000201 6443 5633 2437 4037 2764 NA NA NA NA NA NA NA 12156 FUN_043768 166 213 214 347 93 NA NA NA NA NA NA NA 12157 FUN_043769 206 157 151 289 135 NA NA NA NA NA NA NA 12158 FUN_010979 698 492 365 461 681 NA NA NA NA NA NA NA 12159 FUN_010978 6110 4823 3843 4850 4134 ptg000007l:5156801-5171656 A6N7Y9 5.25e-25 Piwi-like protein 1 (EC 3.1.26.-) Gallus gallus (Chicken) meiotic cell cycle [GO:0051321]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of translation [GO:0006417]; RNA-mediated gene silencing [GO:0031047]; sperm DNA condensation [GO:0035092]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0003723; GO:0003727; GO:0003729; GO:0004521; GO:0005634; GO:0005737; GO:0006417; GO:0007283; GO:0007286; GO:0010529; GO:0019901; GO:0031047; GO:0033391; GO:0034584; GO:0034587; GO:0035092; GO:0043186; GO:0046872; GO:0051321; GO:0097433; GO:0140262; GO:1905538 12160 FUN_043760 0 31 20 70 63 NA NA NA NA NA NA NA 12161 FUN_043761 12 0 0 0 4 NA NA NA NA NA NA NA 12162 FUN_043762 655 1172 971 1371 569 NA NA NA NA NA NA NA 12163 FUN_043764 232 286 262 663 205 ptg000049l:884447-885111 Q62671 3.2e-24 E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (100 kDa protein) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) Rattus norvegicus (Rat) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; negative regulation of interleukin-17 production [GO:0032700]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of gene expression [GO:0010628]; positive regulation of protein import into nucleus [GO:0042307]; progesterone receptor signaling pathway [GO:0050847]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of double-strand break repair [GO:2000779]; regulation of protein stability [GO:0031647] GO:0000209; GO:0003723; GO:0005634; GO:0005737; GO:0005829; GO:0006281; GO:0006974; GO:0008270; GO:0010628; GO:0016567; GO:0019904; GO:0031647; GO:0032700; GO:0032991; GO:0034450; GO:0042307; GO:0043130; GO:0048471; GO:0050847; GO:0061630; GO:0070936; GO:0090263; GO:0140861; GO:1901315; GO:2000779; GO:2000780 12164 FUN_010970 0 20 52 45 21 NA NA NA NA NA NA NA 12165 FUN_043766 64 75 145 296 55 NA NA NA NA NA NA NA 12166 FUN_010972 0 0 52 12 42 NA NA NA NA NA NA NA 12167 FUN_042411 0 0 13 6 0 NA NA NA NA NA NA NA 12168 FUN_042413 0 0 5 14 13 NA NA NA NA NA NA NA 12169 FUN_042412 0 20 0 6 27 NA NA NA NA NA NA NA 12170 FUN_042415 0 0 0 0 39 NA NA NA NA NA NA NA 12171 FUN_042416 1 0 2 3 34 NA NA NA NA NA NA NA 12172 FUN_041692 1209 1726 523 930 691 NA NA NA NA NA NA NA 12173 FUN_041693 567 606 957 1531 1327 NA NA NA NA NA NA NA 12174 FUN_041690 266 124 78 456 404 NA NA NA NA NA NA NA 12175 FUN_041691 24824 38690 20456 30796 25625 NA NA NA NA NA NA NA 12176 FUN_041696 38597 49789 21793 31528 10916 NA NA NA NA NA NA NA 12177 FUN_041697 10 0 0 23 48 NA NA NA NA NA NA NA 12178 FUN_041694 638 570 583 972 966 NA NA NA NA NA NA NA 12179 FUN_041695 499 502 397 997 1102 NA NA NA NA NA NA NA 12180 FUN_041698 2587 2174 1598 2235 1913 ptg000035l:6616950-6656225 A8I1Q0 1.19e-24 Calmodulin (CaM) Heterocapsa triquetra (Dinoflagellate) (Glenodinium triquetrum) NA GO:0005509 12181 FUN_041699 411 152 237 195 235 ptg000035l:6657084-6658753 P49326 1.47e-69 Flavin-containing monooxygenase 5 (FMO 5) (Baeyer-Villiger monooxygenase 1) (hBVMO1) (EC 1.14.13.-) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (NADPH oxidase) (EC 1.6.3.1) Homo sapiens (Human) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005783; GO:0005789; GO:0005829; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 12182 FUN_009138 0 31 20 0 193 NA NA NA NA NA NA NA 12183 FUN_017277 0 0 0 0 9 NA NA NA NA NA NA NA 12184 FUN_009133 129 164 89 59 74 ptg000004l:3077370-3081813 Q96AY4 5.36e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12185 FUN_009133 129 164 89 59 74 ptg000004l:3077370-3081813 Q96AY4 1.74e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12186 FUN_009133 129 164 89 59 74 ptg000004l:3077370-3081813 Q96AY4 8.47e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12187 FUN_009133 129 164 89 59 74 ptg000004l:3077370-3081813 Q96AY4 5.41e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12188 FUN_009133 129 164 89 59 74 ptg000004l:3077370-3081813 Q96AY4 2.87e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12189 FUN_009133 129 164 89 59 74 ptg000004l:3077370-3081813 Q96AY4 4.46e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12190 FUN_009132 11 0 0 13 52 NA NA NA NA NA NA NA 12191 FUN_009131 21 0 11 53 167 NA NA NA NA NA NA NA 12192 FUN_009130 47 279 19 42 122 ptg000004l:3055314-3059509 Q96AY4 2.43e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12193 FUN_009130 47 279 19 42 122 ptg000004l:3055314-3059509 Q96AY4 3.38e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12194 FUN_009130 47 279 19 42 122 ptg000004l:3055314-3059509 Q96AY4 3.69e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12195 FUN_009130 47 279 19 42 122 ptg000004l:3055314-3059509 Q96AY4 5.03e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12196 FUN_009130 47 279 19 42 122 ptg000004l:3055314-3059509 Q96AY4 8.49e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12197 FUN_009137 97 135 43 20 155 ptg000004l:3116108-3120911 Q80XJ3 3.55e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12198 FUN_009137 97 135 43 20 155 ptg000004l:3116108-3120911 Q80XJ3 9.48e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12199 FUN_009137 97 135 43 20 155 ptg000004l:3116108-3120911 Q80XJ3 2.28e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12200 FUN_009137 97 135 43 20 155 ptg000004l:3116108-3120911 Q80XJ3 8.62e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12201 FUN_009137 97 135 43 20 155 ptg000004l:3116108-3120911 Q80XJ3 4.63e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12202 FUN_009137 97 135 43 20 155 ptg000004l:3116108-3120911 Q80XJ3 5.55e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 12203 FUN_009136 7 21 6 8 3 NA NA NA NA NA NA NA 12204 FUN_009135 15 31 43 0 20 NA NA NA NA NA NA NA 12205 FUN_009134 6 2 5 3 144 NA NA NA NA NA NA NA 12206 FUN_022754 97 17 33 25 27 ptg000016l:12720457-12722459 P25291 7.79e-26 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12207 FUN_022754 97 17 33 25 27 ptg000016l:12720457-12722459 P25291 1.03e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12208 FUN_022755 55 10 22 17 28 ptg000016l:12722691-12723711 P25291 4.37e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12209 FUN_022756 24 207 15 89 52 NA NA NA NA NA NA NA 12210 FUN_022757 0 0 2 1 7 NA NA NA NA NA NA NA 12211 FUN_022750 42 6 20 9 13 ptg000016l:12715989-12716469 P25291 1.09e-29 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12212 FUN_022751 51 14 30 18 24 ptg000016l:12717108-12717991 P25291 1.23e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12213 FUN_022752 36 3 12 8 15 ptg000016l:12718223-12718703 P25291 1.51e-29 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12214 FUN_022753 54 11 37 17 26 ptg000016l:12719342-12720225 P25291 1.23e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 12215 FUN_022758 2988 3737 2410 4895 4386 NA NA NA NA NA NA NA 12216 FUN_022759 173 271 131 312 179 NA NA NA NA NA NA NA 12217 FUN_042019 9031 13811 6086 9785 7987 NA NA NA NA NA NA NA 12218 FUN_042018 2641 2028 1965 2585 3120 ptg000035l:9833764-9846959 Q95SX7 8.13e-37 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 12219 FUN_040123 404 0 271 184 217 NA NA NA NA NA NA NA 12220 FUN_040122 45 10 12 0 177 NA NA NA NA NA NA NA 12221 FUN_040121 927 8334 1349 1385 1734 NA NA NA NA NA NA NA 12222 FUN_040120 350 679 232 935 198 ptg000031l:4446197-4470475 P10394 2.22e-26 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 12223 FUN_040120 350 679 232 935 198 ptg000031l:4446197-4470475 P10394 2.22e-26 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 12224 FUN_040120 350 679 232 935 198 ptg000031l:4446197-4470475 P10394 2.22e-26 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 12225 FUN_040125 0 0 6 7 0 NA NA NA NA NA NA NA 12226 FUN_040124 44 18 58 110 89 NA NA NA NA NA NA NA 12227 FUN_040129 594 713 468 279 163 NA NA NA NA NA NA NA 12228 FUN_040128 500 373 598 204 907 NA NA NA NA NA NA NA 12229 FUN_042017 1953 1290 895 1343 1017 NA NA NA NA NA NA NA 12230 FUN_042016 74 2 0 6 0 NA NA NA NA NA NA NA 12231 FUN_015228 333 293 144 609 706 ptg000009l:7689899-7692193 Q1JQC6 4.56e-52 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 2.3.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein biotinylase sirtuin-4) (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; glutamine metabolic process [GO:0006541]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of insulin secretion [GO:0046676]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of lipid biosynthetic process [GO:0046889]; protein deacetylation [GO:0006476]; regulation of pyruvate dehydrogenase activity [GO:1904182]; tricarboxylic acid metabolic process [GO:0072350] GO:0003950; GO:0005739; GO:0005759; GO:0006476; GO:0006541; GO:0006974; GO:0008270; GO:0016779; GO:0019213; GO:0034979; GO:0034983; GO:0046322; GO:0046676; GO:0046889; GO:0070403; GO:0072350; GO:0106419; GO:0106420; GO:0140803; GO:1904182 12232 FUN_015228 333 293 144 609 706 ptg000009l:7689899-7692193 Q1JQC6 4.71e-46 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (EC 2.3.1.-) (NAD-dependent ADP-ribosyltransferase sirtuin-4) (EC 2.4.2.-) (NAD-dependent protein biotinylase sirtuin-4) (EC 2.3.1.-) (NAD-dependent protein deacetylase sirtuin-4) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; glutamine metabolic process [GO:0006541]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of insulin secretion [GO:0046676]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of lipid biosynthetic process [GO:0046889]; protein deacetylation [GO:0006476]; regulation of pyruvate dehydrogenase activity [GO:1904182]; tricarboxylic acid metabolic process [GO:0072350] GO:0003950; GO:0005739; GO:0005759; GO:0006476; GO:0006541; GO:0006974; GO:0008270; GO:0016779; GO:0019213; GO:0034979; GO:0034983; GO:0046322; GO:0046676; GO:0046889; GO:0070403; GO:0072350; GO:0106419; GO:0106420; GO:0140803; GO:1904182 12233 FUN_015229 212 134 62 113 82 NA NA NA NA NA NA NA 12234 FUN_015226 694 141 261 161 463 NA NA NA NA NA NA NA 12235 FUN_015227 170 111 149 209 216 NA NA NA NA NA NA NA 12236 FUN_015225 1035 1860 838 2052 3229 ptg000009l:7659599-7665405 Q6IRI9 9e-65 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Rattus norvegicus (Rat) energy homeostasis [GO:0097009]; NADP metabolic process [GO:0006739]; NADPH oxidation [GO:0070995]; negative regulation of fatty acid oxidation [GO:0046322]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] GO:0004497; GO:0004499; GO:0005789; GO:0006082; GO:0006739; GO:0006805; GO:0009404; GO:0016020; GO:0046322; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0072592; GO:0097009 12237 FUN_015225 1035 1860 838 2052 3229 ptg000009l:7659599-7665405 Q6IRI9 5.35e-56 Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) Rattus norvegicus (Rat) energy homeostasis [GO:0097009]; NADP metabolic process [GO:0006739]; NADPH oxidation [GO:0070995]; negative regulation of fatty acid oxidation [GO:0046322]; organic acid metabolic process [GO:0006082]; oxygen metabolic process [GO:0072592]; toxin metabolic process [GO:0009404]; xenobiotic metabolic process [GO:0006805] GO:0004497; GO:0004499; GO:0005789; GO:0006082; GO:0006739; GO:0006805; GO:0009404; GO:0016020; GO:0046322; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0072592; GO:0097009 12238 FUN_015222 314 184 122 94 408 ptg000009l:7635019-7638792 Q9D5J6 6.08e-44 Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; cellular response to interleukin-13 [GO:0035963]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; glycerol metabolic process [GO:0006071]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; phosphorylation [GO:0016310]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030] GO:0005524; GO:0005737; GO:0005829; GO:0005975; GO:0006071; GO:0009052; GO:0016310; GO:0016773; GO:0035963; GO:0043030; GO:0050277; GO:0050727; GO:0071222; GO:0071353 12239 FUN_015222 314 184 122 94 408 ptg000009l:7635019-7638792 Q9D5J6 5.04e-27 Sedoheptulokinase (SHK) (EC 2.7.1.14) (Carbohydrate kinase-like protein) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; cellular response to interleukin-13 [GO:0035963]; cellular response to interleukin-4 [GO:0071353]; cellular response to lipopolysaccharide [GO:0071222]; glycerol metabolic process [GO:0006071]; pentose-phosphate shunt, non-oxidative branch [GO:0009052]; phosphorylation [GO:0016310]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030] GO:0005524; GO:0005737; GO:0005829; GO:0005975; GO:0006071; GO:0009052; GO:0016310; GO:0016773; GO:0035963; GO:0043030; GO:0050277; GO:0050727; GO:0071222; GO:0071353 12240 FUN_015223 768 625 295 815 322 ptg000009l:7638986-7642249 Q8K4C0 4.85e-75 Flavin-containing monooxygenase 5 (FMO 5) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (NADPH oxidase) (EC 1.6.3.1) Rattus norvegicus (Rat) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005789; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 12241 FUN_015223 768 625 295 815 322 ptg000009l:7638986-7642249 Q8K4C0 1.12e-59 Flavin-containing monooxygenase 5 (FMO 5) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (NADPH oxidase) (EC 1.6.3.1) Rattus norvegicus (Rat) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005789; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 12242 FUN_015220 1560 1067 453 1134 1490 ptg000009l:7603989-7608215 Q9CPV4 4.92e-36 Glyoxalase domain-containing protein 4 Mus musculus (Mouse) NA GO:0005739 12243 FUN_015221 117 0 0 0 0 NA NA NA NA NA NA NA 12244 FUN_024349 0 0 2 22 37 NA NA NA NA NA NA NA 12245 FUN_024348 233 308 236 386 314 NA NA NA NA NA NA NA 12246 FUN_024345 1420 306 394 695 425 NA NA NA NA NA NA NA 12247 FUN_024344 1122 961 455 1149 588 NA NA NA NA NA NA NA 12248 FUN_024347 101 9 35 44 52 NA NA NA NA NA NA NA 12249 FUN_024346 17156 20867 17786 44561 36868 NA NA NA NA NA NA NA 12250 FUN_024341 102 110 46 152 19 NA NA NA NA NA NA NA 12251 FUN_024340 316 157 57 284 287 NA NA NA NA NA NA NA 12252 FUN_024343 8062 6824 3750 5324 4427 NA NA NA NA NA NA NA 12253 FUN_024342 21772 23263 10056 16677 8995 ptg000018l:5084584-5085082 Q63073 4.98e-40 Protein BTG1 (Anti-proliferative factor) (B-cell translocation gene 1 protein) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of mitotic cell cycle [GO:0045930]; positive regulation of angiogenesis [GO:0045766]; positive regulation of endothelial cell differentiation [GO:0045603]; positive regulation of fibroblast apoptotic process [GO:2000271]; positive regulation of myoblast differentiation [GO:0045663]; protein methylation [GO:0006479]; response to oxidative stress [GO:0006979]; response to peptide hormone [GO:0043434]; spermatid development [GO:0007286]; spermatogenesis [GO:0007283] GO:0005634; GO:0005737; GO:0006479; GO:0006979; GO:0007283; GO:0007286; GO:0008283; GO:0008285; GO:0019899; GO:0043434; GO:0045603; GO:0045663; GO:0045766; GO:0045930; GO:2000271 12254 FUN_015133 16 2 32 0 154 NA NA NA NA NA NA NA 12255 FUN_038465 866 490 476 698 890 ptg000027l:7607803-7610743 Q6NUH3 1.14e-56 Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:0061630 12256 FUN_038465 866 490 476 698 890 ptg000027l:7607803-7610743 Q6NUH3 2.14e-36 Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:0061630 12257 FUN_038464 4864 3349 2914 2687 2385 ptg000027l:7601510-7607425 Q58DM8 1.88e-29 Enoyl-CoA hydratase, mitochondrial (mECH) (mECH1) (EC 4.2.1.17) (EC 5.3.3.8) (Enoyl-CoA hydratase 1) (ECHS1) (Short-chain enoyl-CoA hydratase) (SCEH) Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0004165; GO:0004300; GO:0005739; GO:0005759; GO:0006635; GO:0043956; GO:0120092 12258 FUN_038466 235 121 117 256 290 NA NA NA NA NA NA NA 12259 FUN_038461 8 0 0 0 18 NA NA NA NA NA NA NA 12260 FUN_038460 18 0 0 26 28 NA NA NA NA NA NA NA 12261 FUN_038463 108 49 77 74 92 NA NA NA NA NA NA NA 12262 FUN_038462 0 0 0 11 3 NA NA NA NA NA NA NA 12263 FUN_028873 3977 8920 6689 45 4686 NA NA NA NA NA NA NA 12264 FUN_028872 0 32 0 0 65 NA NA NA NA NA NA NA 12265 FUN_028871 6955 8870 9340 48 4404 NA NA NA NA NA NA NA 12266 FUN_028870 0 0 90 0 282 NA NA NA NA NA NA NA 12267 FUN_028877 1365 1211 776 1250 712 NA NA NA NA NA NA NA 12268 FUN_028876 206 172 70 183 105 NA NA NA NA NA NA NA 12269 FUN_028875 106 57 258 94 70 NA NA NA NA NA NA NA 12270 FUN_028874 500 189 897 154 335 NA NA NA NA NA NA NA 12271 FUN_037008 10 1 1 10 9 NA NA NA NA NA NA NA 12272 FUN_004589 8646 6976 1609 4110 1990 NA NA NA NA NA NA NA 12273 FUN_037007 1857 1258 729 1836 1088 NA NA NA NA NA NA NA 12274 FUN_019353 0 0 17 16 24 NA NA NA NA NA NA NA 12275 FUN_015918 0 26 0 25 0 NA NA NA NA NA NA NA 12276 FUN_015915 36 38 20 40 19 NA NA NA NA NA NA NA 12277 FUN_039332 19 38 0 15 0 NA NA NA NA NA NA NA 12278 FUN_039333 55 45 9 15 103 NA NA NA NA NA NA NA 12279 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 1.14e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12280 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 3.48e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12281 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 5.08e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12282 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 4.85e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12283 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 5.45e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12284 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 2.23e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12285 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 8.3e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12286 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 4.05e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12287 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 1.56e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12288 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 3.97e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12289 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 6.87e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12290 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 7.18e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12291 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 1.35e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12292 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 8.63e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12293 FUN_039330 1594 332 789 491 110 ptg000029c:55336-74602 Q7RTR2 6.68e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12294 FUN_039331 237 69 50 51 0 NA NA NA NA NA NA NA 12295 FUN_039336 435 0 0 203 2 NA NA NA NA NA NA NA 12296 FUN_039337 9 7 5 17 7 NA NA NA NA NA NA NA 12297 FUN_039334 175 20 0 48 0 NA NA NA NA NA NA NA 12298 FUN_039335 4 4 0 6 11 NA NA NA NA NA NA NA 12299 FUN_039338 1360 125 232 761 534 ptg000029c:167186-179552 Q7RTR2 2.43e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12300 FUN_039338 1360 125 232 761 534 ptg000029c:167186-179552 Q7RTR2 4.33e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12301 FUN_039338 1360 125 232 761 534 ptg000029c:167186-179552 Q7RTR2 6.69e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12302 FUN_039338 1360 125 232 761 534 ptg000029c:167186-179552 Q7RTR2 4.77e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12303 FUN_039339 44 0 9 0 10 NA NA NA NA NA NA NA 12304 FUN_032239 862 1994 863 3418 2128 ptg000023l:30051120-30054033 Q108U2 5.48e-27 Protein Wnt-2 Loxodonta africana (African elephant) atrial cardiac muscle tissue morphogenesis [GO:0055009]; canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904954]; cardiac epithelial to mesenchymal transition [GO:0060317]; cardiac muscle cell proliferation [GO:0060038]; cell proliferation in midbrain [GO:0033278]; cellular response to transforming growth factor beta stimulus [GO:0071560]; epithelial cell proliferation involved in lung morphogenesis [GO:0060502]; labyrinthine layer blood vessel development [GO:0060716]; lung induction [GO:0060492]; mammary gland epithelium development [GO:0061180]; mesenchymal cell proliferation [GO:0010463]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of neurogenesis [GO:0050769]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0002053; GO:0005109; GO:0005125; GO:0005576; GO:0005737; GO:0010463; GO:0031232; GO:0033278; GO:0045944; GO:0048146; GO:0050769; GO:0051091; GO:0055009; GO:0060038; GO:0060045; GO:0060317; GO:0060492; GO:0060501; GO:0060502; GO:0060716; GO:0061180; GO:0062023; GO:0071560; GO:1904954 12305 FUN_018511 303 26 91 27 141 NA NA NA NA NA NA NA 12306 FUN_032632 1496 940 701 1607 1297 NA NA NA NA NA NA NA 12307 FUN_032633 20 37 19 61 59 NA NA NA NA NA NA NA 12308 FUN_027065 1594 899 703 1454 1046 NA NA NA NA NA NA NA 12309 FUN_027067 1341 958 1000 1529 863 NA NA NA NA NA NA NA 12310 FUN_027066 2951 3170 3220 2266 1838 ptg000020l:16435366-16437459 Q504M2 3.56e-50 NA NA NA NA 12311 FUN_027060 15 0 0 17 0 NA NA NA NA NA NA NA 12312 FUN_027063 0 0 4 15 17 NA NA NA NA NA NA NA 12313 FUN_006566 70 65 0 145 64 ptg000001l:14173265-14182402 Q7RTR2 2.84e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12314 FUN_006566 70 65 0 145 64 ptg000001l:14173265-14182402 Q7RTR2 2.65e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12315 FUN_006566 70 65 0 145 64 ptg000001l:14173265-14182402 Q7RTR2 6.22e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12316 FUN_006566 70 65 0 145 64 ptg000001l:14173265-14182402 Q7RTR2 1.52e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12317 FUN_006566 70 65 0 145 64 ptg000001l:14173265-14182402 Q7RTR2 1.84e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12318 FUN_032636 118 0 68 71 52 NA NA NA NA NA NA NA 12319 FUN_032637 1013 631 525 538 683 ptg000023l:34155413-34171391 Q6RUV5 2e-33 Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament polymerization [GO:0030041]; anatomical structure arrangement [GO:0048532]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; auditory receptor cell morphogenesis [GO:0002093]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; cell motility [GO:0048870]; cell population proliferation [GO:0008283]; cell projection assembly [GO:0030031]; cell-cell junction organization [GO:0045216]; cellular response to mechanical stimulus [GO:0071260]; cerebral cortex GABAergic interneuron development [GO:0021894]; cerebral cortex radially oriented cell migration [GO:0021799]; chemotaxis [GO:0006935]; cochlea morphogenesis [GO:0090103]; cortical cytoskeleton organization [GO:0030865]; cytoskeleton organization [GO:0007010]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dopaminergic neuron differentiation [GO:0071542]; embryonic olfactory bulb interneuron precursor migration [GO:0021831]; endocytosis [GO:0006897]; engulfment of apoptotic cell [GO:0043652]; epithelial cell morphogenesis [GO:0003382]; establishment or maintenance of cell polarity [GO:0007163]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; homeostasis of number of cells within a tissue [GO:0048873]; hyperosmotic response [GO:0006972]; interneuron migration [GO:1904936]; lamellipodium assembly [GO:0030032]; localization [GO:0051179]; localization within membrane [GO:0051668]; mast cell chemotaxis [GO:0002551]; midbrain dopaminergic neuron differentiation [GO:1904948]; motor neuron axon guidance [GO:0008045]; negative regulation of fibroblast migration [GO:0010764]; negative regulation of interleukin-23 production [GO:0032707]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; non-canonical Wnt signaling pathway [GO:0035567]; phagocytosis, engulfment [GO:0006911]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA replication [GO:0045740]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of lamellipodium assembly [GO:0010592]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neutrophil chemotaxis [GO:0090023]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynaptic actin cytoskeleton organization [GO:0098974]; protein localization to plasma membrane [GO:0072659]; Rac protein signal transduction [GO:0016601]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell adhesion involved in heart morphogenesis [GO:0061344]; regulation of cell migration [GO:0030334]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of cell size [GO:0008361]; regulation of ERK5 cascade [GO:0070376]; regulation of fibroblast migration [GO:0010762]; regulation of lamellipodium assembly [GO:0010591]; regulation of neuron maturation [GO:0014041]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neutrophil migration [GO:1902622]; regulation of nitric oxide biosynthetic process [GO:0045428]; regulation of receptor signaling pathway via JAK-STAT [GO:0046425]; regulation of respiratory burst [GO:0060263]; regulation of stress fiber assembly [GO:0051492]; ruffle assembly [GO:0097178]; ruffle organization [GO:0031529]; semaphorin-plexin signaling pathway [GO:0071526]; small GTPase mediated signal transduction [GO:0007264]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0000139; GO:0000242; GO:0001764; GO:0001891; GO:0001934; GO:0002093; GO:0002551; GO:0003376; GO:0003382; GO:0003924; GO:0003925; GO:0005525; GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0006897; GO:0006911; GO:0006935; GO:0006972; GO:0007010; GO:0007015; GO:0007155; GO:0007163; GO:0007186; GO:0007264; GO:0007411; GO:0008045; GO:0008283; GO:0008360; GO:0008361; GO:0010591; GO:0010592; GO:0010595; GO:0010762; GO:0010764; GO:0010811; GO:0014041; GO:0016020; GO:0016358; GO:0016477; GO:0016601; GO:0019897; GO:0019899; GO:0019901; GO:0021799; GO:0021831; GO:0021894; GO:0022604; GO:0030027; GO:0030031; GO:0030032; GO:0030036; GO:0030041; GO:0030334; GO:0030742; GO:0030838; GO:0030865; GO:0030900; GO:0031116; GO:0031234; GO:0031267; GO:0031410; GO:0031529; GO:0031901; GO:0031996; GO:0032587; GO:0032707; GO:0032956; GO:0034446; GO:0035567; GO:0035774; GO:0036464; GO:0042470; GO:0042826; GO:0042995; GO:0043197; GO:0043552; GO:0043652; GO:0044877; GO:0045216; GO:0045428; GO:0045453; GO:0045740; GO:0046425; GO:0048012; GO:0048168; GO:0048532; GO:0048812; GO:0048813; GO:0048870; GO:0048873; GO:0051022; GO:0051117; GO:0051179; GO:0051491; GO:0051492; GO:0051496; GO:0051668; GO:0051894; GO:0051932; GO:0055038; GO:0060071; GO:0060090; GO:0060091; GO:0060263; GO:0060999; GO:0061344; GO:0070376; GO:0071260; GO:0071526; GO:0071542; GO:0072659; GO:0086098; GO:0090023; GO:0090103; GO:0097178; GO:0098794; GO:0098974; GO:0098978; GO:0098982; GO:1900026; GO:1902622; GO:1904936; GO:1904948; GO:2000386; GO:2001222 12320 FUN_006823 13 0 0 61 6 ptg000001l:17072281-17078599 P32114 1.74e-58 Paired box protein Pax-2 Mus musculus (Mouse) anatomical structure development [GO:0048856]; brain morphogenesis [GO:0048854]; branching involved in ureteric bud morphogenesis [GO:0001658]; camera-type eye development [GO:0043010]; cell fate determination [GO:0001709]; cellular response to glucose stimulus [GO:0071333]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to mechanical stimulus [GO:0071260]; cellular response to retinoic acid [GO:0071300]; central nervous system development [GO:0007417]; cochlea development [GO:0090102]; cochlea morphogenesis [GO:0090103]; dopaminergic neuron differentiation [GO:0071542]; glial cell differentiation [GO:0010001]; inner ear morphogenesis [GO:0042472]; kidney development [GO:0001822]; mesenchymal to epithelial transition [GO:0060231]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; mesodermal cell fate specification [GO:0007501]; mesonephric duct development [GO:0072177]; mesonephric tubule development [GO:0072164]; mesonephric tubule formation [GO:0072172]; mesonephros development [GO:0001823]; metanephric collecting duct development [GO:0072205]; metanephric distal convoluted tubule development [GO:0072221]; metanephric epithelium development [GO:0072207]; metanephric mesenchymal cell differentiation [GO:0072162]; metanephric mesenchyme development [GO:0072075]; metanephric nephron tubule formation [GO:0072289]; metanephros development [GO:0001656]; negative regulation of apoptotic process [GO:0043066]; negative regulation of apoptotic process involved in metanephric collecting duct development [GO:1900215]; negative regulation of apoptotic process involved in metanephric nephron tubule development [GO:1900218]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis [GO:0072305]; negative regulation of mesenchymal cell apoptotic process involved in metanephros development [GO:1900212]; negative regulation of programmed cell death [GO:0043069]; negative regulation of reactive oxygen species metabolic process [GO:2000378]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephric duct formation [GO:0072179]; neural tube closure [GO:0001843]; optic chiasma development [GO:0061360]; optic cup morphogenesis involved in camera-type eye development [GO:0002072]; optic nerve development [GO:0021554]; optic nerve morphogenesis [GO:0021631]; optic nerve structural organization [GO:0021633]; pancreas development [GO:0031016]; paramesonephric duct development [GO:0061205]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0072108]; positive regulation of metanephric DCT cell differentiation [GO:2000594]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of optic nerve formation [GO:2000597]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pronephric field specification [GO:0039003]; pronephros development [GO:0048793]; protein kinase B signaling [GO:0043491]; reactive oxygen species metabolic process [GO:0072593]; regulation of apoptotic process [GO:0042981]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307]; regulation of metanephros size [GO:0035566]; regulation of programmed cell death [GO:0043067]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal pigment epithelium development [GO:0003406]; stem cell differentiation [GO:0048863]; ureter development [GO:0072189]; ureter maturation [GO:0035799]; ureter morphogenesis [GO:0072197]; ureteric bud development [GO:0001657]; urogenital system development [GO:0001655]; vestibulocochlear nerve formation [GO:0021650] GO:0000122; GO:0000976; GO:0000978; GO:0000981; GO:0000987; GO:0001655; GO:0001656; GO:0001657; GO:0001658; GO:0001709; GO:0001822; GO:0001823; GO:0001843; GO:0002072; GO:0003337; GO:0003406; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005764; GO:0005815; GO:0006357; GO:0007417; GO:0007501; GO:0008284; GO:0010001; GO:0021554; GO:0021631; GO:0021633; GO:0021650; GO:0031016; GO:0032991; GO:0032993; GO:0034451; GO:0035566; GO:0035799; GO:0039003; GO:0042472; GO:0042981; GO:0043010; GO:0043066; GO:0043067; GO:0043069; GO:0043154; GO:0043491; GO:0045892; GO:0045893; GO:0045944; GO:0048793; GO:0048854; GO:0048856; GO:0048863; GO:0050679; GO:0060231; GO:0061205; GO:0061360; GO:0070301; GO:0070742; GO:0071260; GO:0071300; GO:0071333; GO:0071542; GO:0072075; GO:0072108; GO:0072162; GO:0072164; GO:0072172; GO:0072177; GO:0072179; GO:0072189; GO:0072197; GO:0072205; GO:0072207; GO:0072221; GO:0072289; GO:0072300; GO:0072305; GO:0072307; GO:0072593; GO:0090102; GO:0090103; GO:0090190; GO:1900212; GO:1900215; GO:1900218; GO:1990837; GO:2000378; GO:2000594; GO:2000597 12321 FUN_005188 272 93 185 152 555 NA NA NA NA NA NA NA 12322 FUN_032638 505 228 88 6 346 NA NA NA NA NA NA NA 12323 FUN_017204 0 0 0 23 0 NA NA NA NA NA NA NA 12324 FUN_017202 3 0 0 26 19 NA NA NA NA NA NA NA 12325 FUN_017203 21 0 0 0 16 NA NA NA NA NA NA NA 12326 FUN_006569 23 0 24 0 113 NA NA NA NA NA NA NA 12327 FUN_004132 39 93 22 39 30 NA NA NA NA NA NA NA 12328 FUN_033585 18 23 0 0 11 NA NA NA NA NA NA NA 12329 FUN_004638 5202 3649 2455 4422 2197 NA NA NA NA NA NA NA 12330 FUN_004636 1325 448 538 1842 1555 NA NA NA NA NA NA NA 12331 FUN_031635 510 411 698 736 867 ptg000023l:23690479-23703712 O15381 9.87e-26 Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of telomerase activity [GO:0051973]; regulation of protein localization to nucleolus [GO:1904749]; ribosomal large subunit biogenesis [GO:0042273]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] GO:0003723; GO:0005524; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0006364; GO:0016020; GO:0016887; GO:0032092; GO:0042254; GO:0042273; GO:0051973; GO:1904749; GO:1990275 12332 FUN_031635 510 411 698 736 867 ptg000023l:23690479-23703712 O15381 9.87e-26 Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) Homo sapiens (Human) positive regulation of protein binding [GO:0032092]; positive regulation of telomerase activity [GO:0051973]; regulation of protein localization to nucleolus [GO:1904749]; ribosomal large subunit biogenesis [GO:0042273]; ribosome biogenesis [GO:0042254]; rRNA processing [GO:0006364] GO:0003723; GO:0005524; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0006364; GO:0016020; GO:0016887; GO:0032092; GO:0042254; GO:0042273; GO:0051973; GO:1904749; GO:1990275 12333 FUN_027933 2448 1136 1175 1913 1460 NA NA NA NA NA NA NA 12334 FUN_027932 2830 1390 1297 1833 1364 NA NA NA NA NA NA NA 12335 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 9.61e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12336 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 1.87e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12337 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 4.56e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12338 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 2.17e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12339 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 2.58e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12340 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 6.37e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12341 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 2.03e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12342 FUN_018155 648 213 230 566 961 ptg000012l:5048748-5066234 Q96AY4 3.63e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12343 FUN_031634 185 290 293 349 442 NA NA NA NA NA NA NA 12344 FUN_027937 905 494 830 1822 1117 NA NA NA NA NA NA NA 12345 FUN_018152 38 35 10 73 17 ptg000012l:4968848-4978241 Q9UEW3 1.53e-24 Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898] GO:0001540; GO:0001664; GO:0001934; GO:0004888; GO:0005044; GO:0005581; GO:0005737; GO:0005886; GO:0006897; GO:0006898; GO:0006911; GO:0007166; GO:0007193; GO:0030666; GO:0038024; GO:0038187; GO:0043277; GO:0045087; GO:0070374; GO:0097242 12346 FUN_018151 1 0 8 0 10 NA NA NA NA NA NA NA 12347 FUN_027934 2056 2261 1192 2842 1519 NA NA NA NA NA NA NA 12348 FUN_031633 1134 1009 716 698 550 NA NA NA NA NA NA NA 12349 FUN_027939 704 720 260 591 281 NA NA NA NA NA NA NA 12350 FUN_027938 3685 12113 5088 12483 7824 NA NA NA NA NA NA NA 12351 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 4.41e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12352 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 1.25e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12353 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 6.9e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12354 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 2.36e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12355 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 2.8e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12356 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 2.15e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12357 FUN_018159 231 63 127 225 88 ptg000012l:5134282-5145916 Q96AY4 5.45e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12358 FUN_018158 1 0 0 0 9 NA NA NA NA NA NA NA 12359 FUN_031631 21 25 97 51 46 NA NA NA NA NA NA NA 12360 FUN_017899 2603 2157 1143 2442 1498 ptg000012l:1697336-1705300 A0JMY4 6.13e-22 Basal body-orientation factor 1 (Coiled-coil domain-containing protein 176) Xenopus laevis (African clawed frog) motile cilium assembly [GO:0044458] GO:0005737; GO:0036064; GO:0044458 12361 FUN_026084 73 5 48 3 488 NA NA NA NA NA NA NA 12362 FUN_026085 60 8 27 3 316 NA NA NA NA NA NA NA 12363 FUN_026086 206 119 22 153 366 NA NA NA NA NA NA NA 12364 FUN_026087 972 163 147 676 202 NA NA NA NA NA NA NA 12365 FUN_026080 9416 15683 13965 3041 4361 NA NA NA NA NA NA NA 12366 FUN_026081 8299 19793 8563 8405 5879 NA NA NA NA NA NA NA 12367 FUN_026082 3 9 11 15 2 NA NA NA NA NA NA NA 12368 FUN_026083 584 903 600 635 393 NA NA NA NA NA NA NA 12369 FUN_026088 2843 4116 2261 3524 2774 NA NA NA NA NA NA NA 12370 FUN_025575 294 137 118 166 182 ptg000019l:4611585-4615761 Q92113 2.73e-66 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 12371 FUN_025574 41 17 34 0 64 ptg000019l:4609582-4610651 O57525 4.39e-33 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 12372 FUN_025577 50 100 28 86 149 ptg000019l:4623203-4624304 P30437 9.76e-69 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0042448; GO:0047442 12373 FUN_025576 232 339 100 837 355 ptg000019l:4618283-4619015 P02752 7.08e-52 Riboflavin-binding protein (RBP) [Cleaved into: Riboflavin-binding protein, plasma form; Riboflavin-binding protein, yolk major form; Riboflavin-binding protein, yolk minor form] Gallus gallus (Chicken) negative regulation of sensory perception of bitter taste [GO:1904661]; negative regulation of sensory perception of sweet taste [GO:1904657]; riboflavin transport [GO:0032218] GO:0009897; GO:0032217; GO:0032218; GO:0038023; GO:1902444; GO:1904657; GO:1904661 12374 FUN_025571 494 314 313 540 404 NA NA NA NA NA NA NA 12375 FUN_025570 87 11 0 52 57 NA NA NA NA NA NA NA 12376 FUN_025573 255 241 118 243 211 NA NA NA NA NA NA NA 12377 FUN_025572 803 527 471 469 681 NA NA NA NA NA NA NA 12378 FUN_025579 1261 2193 733 1792 995 NA NA NA NA NA NA NA 12379 FUN_025578 3542 1950 1203 1643 1730 ptg000019l:4630416-4634817 Q8N2K1 2.61e-24 Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2) Homo sapiens (Human) positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000151; GO:0000209; GO:0005524; GO:0005634; GO:0005783; GO:0005789; GO:0005829; GO:0006986; GO:0030433; GO:0031625; GO:0061631; GO:1903955 12380 FUN_025578 3542 1950 1203 1643 1730 ptg000019l:4630416-4634817 Q8N2K1 2.61e-24 Ubiquitin-conjugating enzyme E2 J2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J2) (Non-canonical ubiquitin-conjugating enzyme 2) (NCUBE-2) Homo sapiens (Human) positive regulation of protein targeting to mitochondrion [GO:1903955]; protein polyubiquitination [GO:0000209]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000151; GO:0000209; GO:0005524; GO:0005634; GO:0005783; GO:0005789; GO:0005829; GO:0006986; GO:0030433; GO:0031625; GO:0061631; GO:1903955 12381 FUN_013263 141 99 65 28 222 ptg000008l:20384173-20386228 Q0V8L6 1.97e-132 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 12382 FUN_025139 10 25 6 20 56 NA NA NA NA NA NA NA 12383 FUN_017896 127 281 76 120 55 NA NA NA NA NA NA NA 12384 FUN_017894 74 64 102 78 67 NA NA NA NA NA NA NA 12385 FUN_019204 65 58 35 25 67 NA NA NA NA NA NA NA 12386 FUN_019205 55 67 18 25 83 NA NA NA NA NA NA NA 12387 FUN_019206 0 0 0 0 9 NA NA NA NA NA NA NA 12388 FUN_019200 0 0 0 0 9 NA NA NA NA NA NA NA 12389 FUN_019201 8 0 1 0 0 NA NA NA NA NA NA NA 12390 FUN_019202 19 0 0 0 21 NA NA NA NA NA NA NA 12391 FUN_019203 12 0 0 0 0 NA NA NA NA NA NA NA 12392 FUN_002628 812 28 331 40 34 NA NA NA NA NA NA NA 12393 FUN_024628 2524 2547 1627 2474 2661 NA NA NA NA NA NA NA 12394 FUN_024629 2162 1780 1233 1964 1721 NA NA NA NA NA NA NA 12395 FUN_024622 1929 509 1034 540 426 NA NA NA NA NA NA NA 12396 FUN_024623 0 0 0 0 16 NA NA NA NA NA NA NA 12397 FUN_024620 2778 2409 1492 1703 1512 NA NA NA NA NA NA NA 12398 FUN_024621 39 43 33 50 96 NA NA NA NA NA NA NA 12399 FUN_024626 173 271 256 344 124 NA NA NA NA NA NA NA 12400 FUN_024627 25 106 41 63 26 NA NA NA NA NA NA NA 12401 FUN_024624 59 17 77 31 92 NA NA NA NA NA NA NA 12402 FUN_024625 293 116 522 510 235 NA NA NA NA NA NA NA 12403 FUN_005934 0 0 0 0 90 NA NA NA NA NA NA NA 12404 FUN_005931 296 148 490 0 183 NA NA NA NA NA NA NA 12405 FUN_005930 0 0 27 0 0 NA NA NA NA NA NA NA 12406 FUN_005939 5 51 48 14 1 NA NA NA NA NA NA NA 12407 FUN_005938 0 22 17 4 8 NA NA NA NA NA NA NA 12408 FUN_021052 3 173 164 0 18 NA NA NA NA NA NA NA 12409 FUN_021053 0 0 0 4 15 NA NA NA NA NA NA NA 12410 FUN_021050 0 0 17 3 0 NA NA NA NA NA NA NA 12411 FUN_021054 36 0 26 0 0 ptg000016l:301966-305968 P35067 1.29e-71 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 12412 FUN_021055 108 1 69 10 490 ptg000016l:308655-308967 Q6LAF1 8.99e-56 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 12413 FUN_028377 163 186 74 163 80 NA NA NA NA NA NA NA 12414 FUN_028110 13 19 0 0 36 NA NA NA NA NA NA NA 12415 FUN_028111 331 70 57 137 244 NA NA NA NA NA NA NA 12416 FUN_023227 1407 1237 1001 2098 1622 NA NA NA NA NA NA NA 12417 FUN_028113 135 91 70 245 50 NA NA NA NA NA NA NA 12418 FUN_023226 411 213 176 192 413 NA NA NA NA NA NA NA 12419 FUN_028114 965 683 694 1237 1374 NA NA NA NA NA NA NA 12420 FUN_023225 2165 1618 729 1990 1981 ptg000017l:5232246-5241423 Q9DBT4 4.29e-21 Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (EC 3.6.1.15) (EC 3.6.1.6) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase) (EC 3.6.1.42) Mus musculus (Mouse) CTP metabolic process [GO:0046036]; GDP catabolic process [GO:0046712]; nucleobase-containing small molecule catabolic process [GO:0034656]; nucleoside diphosphate catabolic process [GO:0009134]; UDP catabolic process [GO:0006256] GO:0000139; GO:0000421; GO:0004382; GO:0005765; GO:0005794; GO:0006256; GO:0009134; GO:0016020; GO:0017110; GO:0017111; GO:0031410; GO:0034656; GO:0036384; GO:0043273; GO:0045134; GO:0046036; GO:0046712 12421 FUN_023224 7589 6035 3492 6770 6202 ptg000017l:5217905-5231680 Q5ZJK8 1.18e-59 T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0005524; GO:0005832; GO:0006457; GO:0016887; GO:0051082; GO:0140662 12422 FUN_023224 7589 6035 3492 6770 6202 ptg000017l:5217905-5231680 Q5ZJK8 1.49e-47 T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0005524; GO:0005832; GO:0006457; GO:0016887; GO:0051082; GO:0140662 12423 FUN_023224 7589 6035 3492 6770 6202 ptg000017l:5217905-5231680 Q5ZJK8 2.38e-22 T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) Gallus gallus (Chicken) protein folding [GO:0006457] GO:0005524; GO:0005832; GO:0006457; GO:0016887; GO:0051082; GO:0140662 12424 FUN_028116 1330 726 337 797 596 NA NA NA NA NA NA NA 12425 FUN_023223 854 615 332 870 608 NA NA NA NA NA NA NA 12426 FUN_023222 18 0 0 3 14 NA NA NA NA NA NA NA 12427 FUN_038148 477 287 219 323 536 NA NA NA NA NA NA NA 12428 FUN_038149 3 0 8 47 23 NA NA NA NA NA NA NA 12429 FUN_014582 160 78 35 75 169 NA NA NA NA NA NA NA 12430 FUN_038142 1620 859 701 1360 1027 NA NA NA NA NA NA NA 12431 FUN_038143 13433 15027 8277 15750 11094 NA NA NA NA NA NA NA 12432 FUN_038140 3237 3253 2638 3355 1802 ptg000027l:2977453-2989102 A6NH52 3.13e-31 Golgi apparatus membrane protein TVP23 homolog A Homo sapiens (Human) protein secretion [GO:0009306]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0009306; GO:0016192 12433 FUN_038141 756 570 312 569 620 ptg000027l:2989294-2995937 A7RUD5 7.09e-26 Cytosolic Fe-S cluster assembly factor NUBP1 homolog Nematostella vectensis (Starlet sea anemone) iron-sulfur cluster assembly [GO:0016226] GO:0005524; GO:0005829; GO:0016226; GO:0046872; GO:0051536; GO:0051539; GO:0140663 12434 FUN_038146 620 715 435 492 526 NA NA NA NA NA NA NA 12435 FUN_038147 671 432 248 627 646 NA NA NA NA NA NA NA 12436 FUN_038144 2234 1549 1334 3459 2528 ptg000027l:3024701-3048279 P10978 5.81e-123 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 12437 FUN_038145 908 334 397 381 461 NA NA NA NA NA NA NA 12438 FUN_035679 2624 2880 2148 1931 1508 ptg000025l:10576545-10581848 Q9D0M0 1.12e-23 Exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) Mus musculus (Mouse) exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000467]; nuclear mRNA surveillance [GO:0071028]; nuclear polyadenylation-dependent mRNA catabolic process [GO:0071042]; nuclear polyadenylation-dependent rRNA catabolic process [GO:0071035]; nuclear polyadenylation-dependent tRNA catabolic process [GO:0071038]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; U1 snRNA 3'-end processing [GO:0034473]; U4 snRNA 3'-end processing [GO:0034475]; U5 snRNA 3'-end processing [GO:0034476] GO:0000176; GO:0000177; GO:0000178; GO:0000467; GO:0003723; GO:0005634; GO:0005730; GO:0005829; GO:0006396; GO:0006401; GO:0016075; GO:0034427; GO:0034473; GO:0034475; GO:0034476; GO:0043928; GO:0071028; GO:0071035; GO:0071038; GO:0071042; GO:0101019 12439 FUN_035678 3284 2975 1495 2635 1747 ptg000025l:10568499-10575058 Q0VCI1 5.07e-44 tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP) Bos taurus (Bovine) tRNA threonylcarbamoyladenosine modification [GO:0002949] GO:0000408; GO:0002949; GO:0005634; GO:0005737; GO:0005886; GO:0016607; GO:0046872; GO:0061711 12440 FUN_035677 2199 1552 1358 1830 1702 NA NA NA NA NA NA NA 12441 FUN_035676 2017 1401 1113 1573 1700 ptg000025l:10550289-10551036 A0PJN4 5.14e-68 Ubiquitin-conjugating enzyme E2Q-like protein 1 (EC 2.3.2.23) (E2Q-like ubiquitin-conjugating enzyme 1) Mus musculus (Mouse) protein polyubiquitination [GO:0000209] GO:0000209; GO:0005524; GO:0005634; GO:0005654; GO:0005886; GO:0061631 12442 FUN_035675 937 648 464 728 885 NA NA NA NA NA NA NA 12443 FUN_035674 195 253 100 197 181 NA NA NA NA NA NA NA 12444 FUN_035673 758 534 509 732 663 ptg000025l:10526894-10529638 Q8BID8 6.88e-30 F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14) Mus musculus (Mouse) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0006511; GO:0019005; GO:0031146 12445 FUN_035672 2823 3586 1617 2016 1531 NA NA NA NA NA NA NA 12446 FUN_035671 602 660 429 436 782 NA NA NA NA NA NA NA 12447 FUN_035670 2881 2908 1936 2509 1908 ptg000025l:10512654-10517308 Q9PV94 1.02e-42 Small nuclear ribonucleoprotein-associated protein B' (snRNP-B') (snRPB') (Sm protein B') (Sm-B') (SmB') Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; protein methylation [GO:0006479]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0005634; GO:0005654; GO:0005682; GO:0005683; GO:0005685; GO:0005686; GO:0005687; GO:0005689; GO:0005697; GO:0005737; GO:0005829; GO:0006479; GO:0034709; GO:0034719; GO:0046540; GO:0070034; GO:0071004; GO:0071005; GO:0071007; GO:0071013 12448 FUN_001898 9944 11750 6714 7224 4626 NA NA NA NA NA NA NA 12449 FUN_001899 6876 9089 3174 4759 5019 NA NA NA NA NA NA NA 12450 FUN_001894 21 3 27 9 59 NA NA NA NA NA NA NA 12451 FUN_001896 14 0 10 3 60 NA NA NA NA NA NA NA 12452 FUN_001897 25 5 5 4 13 NA NA NA NA NA NA NA 12453 FUN_001890 85 3 9 174 12 NA NA NA NA NA NA NA 12454 FUN_001891 36 0 0 0 10 NA NA NA NA NA NA NA 12455 FUN_001893 66 0 0 0 0 NA NA NA NA NA NA NA 12456 FUN_020010 0 0 0 0 60 NA NA NA NA NA NA NA 12457 FUN_036099 3902 1562 1369 2686 1047 NA NA NA NA NA NA NA 12458 FUN_036092 3442 2664 1794 2646 1503 NA NA NA NA NA NA NA 12459 FUN_036090 44 13 37 21 16 NA NA NA NA NA NA NA 12460 FUN_036091 206 85 122 202 39 NA NA NA NA NA NA NA 12461 FUN_036096 877 340 224 345 373 ptg000025l:15365036-15367493 Q9NP78 0 ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) Homo sapiens (Human) antigen processing and presentation of endogenous peptide antigen via MHC class I [GO:0019885]; peptide metabolic process [GO:0006518]; peptide transport [GO:0015833]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] GO:0005524; GO:0005764; GO:0005765; GO:0005789; GO:0006518; GO:0015031; GO:0015421; GO:0015433; GO:0015440; GO:0015833; GO:0016020; GO:0016887; GO:0019885; GO:0022857; GO:0042626; GO:0042803; GO:0042824; GO:0043231; GO:0046978; GO:0055085 12462 FUN_036097 1566 531 268 538 357 NA NA NA NA NA NA NA 12463 FUN_036094 184 67 99 323 196 NA NA NA NA NA NA NA 12464 FUN_036095 7719 4399 2859 4960 3231 ptg000025l:15352324-15364882 Q2HJG5 6.36e-33 Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) Bos taurus (Bovine) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion to lysosome transport [GO:0099074]; negative regulation of inflammatory response [GO:0050728]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of neuron death [GO:1901215]; neurotransmitter receptor transport, endosome to plasma membrane [GO:0099639]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of gene expression [GO:0010628]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein catabolic process [GO:0045732]; protein localization to endosome [GO:0036010]; regulation of dendritic spine maintenance [GO:1902950]; regulation of protein stability [GO:0031647]; regulation of terminal button organization [GO:2000331]; retrograde transport, endosome to Golgi [GO:0042147]; transcytosis [GO:0045056] GO:0005739; GO:0005764; GO:0005768; GO:0005769; GO:0005770; GO:0005829; GO:0006886; GO:0010008; GO:0010628; GO:0030904; GO:0030906; GO:0031647; GO:0031748; GO:0032456; GO:0036010; GO:0042147; GO:0043653; GO:0045056; GO:0045732; GO:0050728; GO:0060161; GO:0090141; GO:0097422; GO:0099073; GO:0099074; GO:0099639; GO:1901215; GO:1902823; GO:1902950; GO:2000331 12465 FUN_036095 7719 4399 2859 4960 3231 ptg000025l:15352324-15364882 Q2HJG5 1.71e-30 Vacuolar protein sorting-associated protein 35 (Vesicle protein sorting 35) Bos taurus (Bovine) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrion to lysosome transport [GO:0099074]; negative regulation of inflammatory response [GO:0050728]; negative regulation of late endosome to lysosome transport [GO:1902823]; negative regulation of neuron death [GO:1901215]; neurotransmitter receptor transport, endosome to plasma membrane [GO:0099639]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of gene expression [GO:0010628]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein catabolic process [GO:0045732]; protein localization to endosome [GO:0036010]; regulation of dendritic spine maintenance [GO:1902950]; regulation of protein stability [GO:0031647]; regulation of terminal button organization [GO:2000331]; retrograde transport, endosome to Golgi [GO:0042147]; transcytosis [GO:0045056] GO:0005739; GO:0005764; GO:0005768; GO:0005769; GO:0005770; GO:0005829; GO:0006886; GO:0010008; GO:0010628; GO:0030904; GO:0030906; GO:0031647; GO:0031748; GO:0032456; GO:0036010; GO:0042147; GO:0043653; GO:0045056; GO:0045732; GO:0050728; GO:0060161; GO:0090141; GO:0097422; GO:0099073; GO:0099074; GO:0099639; GO:1901215; GO:1902823; GO:1902950; GO:2000331 12466 FUN_001766 28392 49419 20757 17631 10246 NA NA NA NA NA NA NA 12467 FUN_001767 0 0 0 7 0 NA NA NA NA NA NA NA 12468 FUN_001764 0 63 14 0 0 ntLink_6:15826430-15827954 P49582 4.11e-34 Neuronal acetylcholine receptor subunit alpha-7 Mus musculus (Mouse) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; chemical synaptic transmission [GO:0007268]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of acetylcholine biosynthetic process [GO:1905923]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synapse structural plasticity [GO:0051823]; regulation of synaptic transmission, cholinergic [GO:0032222]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032222; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051823; GO:0051899; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098690; GO:0098793; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:1905923; GO:2000463; GO:2001023 12469 FUN_001765 2646 2125 1010 1939 1285 NA NA NA NA NA NA NA 12470 FUN_001762 0 0 0 28 46 ntLink_6:15755427-15766066 C5G6D7 2.14e-27 Chondroitin sulfate ABC exolyase (EC 4.2.2.21) (Chondroitin ABC exoeliminase) (Chondroitin ABC lyase II) (Chondroitin sulfate ABC lyase II) (ChS ABC lyase II) (Chondroitinase ABC II) (cABC II) (Exochondroitinase ABC) Bacteroides thetaiotaomicron carbohydrate metabolic process [GO:0005975]; dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027] GO:0000287; GO:0005509; GO:0005576; GO:0005975; GO:0006027; GO:0030209; GO:0030246; GO:0034000; GO:0034001; GO:0042597 12471 FUN_001768 56 46 19 91 0 NA NA NA NA NA NA NA 12472 FUN_001769 379 790 316 848 643 NA NA NA NA NA NA NA 12473 FUN_036325 0 13 0 0 0 NA NA NA NA NA NA NA 12474 FUN_007648 0 11 0 0 0 NA NA NA NA NA NA NA 12475 FUN_007646 3010 1366 1317 3000 2967 NA NA NA NA NA NA NA 12476 FUN_007645 27923 24153 14549 23883 12291 ptg000002l:2829633-2833327 Q9Z3R8 7.85e-60 Probable alpha-glucosidase (EC 3.2.1.20) Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) NA GO:0032450 12477 FUN_007642 0 0 0 0 30 NA NA NA NA NA NA NA 12478 FUN_027548 6 3 0 0 0 NA NA NA NA NA NA NA 12479 FUN_027549 45 64 20 67 38 NA NA NA NA NA NA NA 12480 FUN_032399 31 0 0 0 15 NA NA NA NA NA NA NA 12481 FUN_027541 62 13 20 8 117 NA NA NA NA NA NA NA 12482 FUN_000387 2142 936 1092 1750 1283 NA NA NA NA NA NA NA 12483 FUN_000385 172 422 380 661 424 NA NA NA NA NA NA NA 12484 FUN_000384 2445 1481 960 2358 1572 NA NA NA NA NA NA NA 12485 FUN_000383 6573 2609 10148 6871 6226 NA NA NA NA NA NA NA 12486 FUN_000382 0 14 0 6 175 ntLink_6:2254349-2255441 Q8NHM4 2.96e-28 Putative trypsin-6 (EC 3.4.21.4) (Serine protease 3 pseudogene 2) (Trypsinogen C) Homo sapiens (Human) endothelial cell migration [GO:0043542]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0043542; GO:0046872 12487 FUN_000381 0 10 9 0 7 NA NA NA NA NA NA NA 12488 FUN_041269 48 15 24 14 76 NA NA NA NA NA NA NA 12489 FUN_000389 20 37 35 16 42 NA NA NA NA NA NA NA 12490 FUN_000388 29 51 6 49 13 NA NA NA NA NA NA NA 12491 FUN_033318 6 0 0 15 11 NA NA NA NA NA NA NA 12492 FUN_033319 0 0 0 0 7 NA NA NA NA NA NA NA 12493 FUN_033316 54 0 9 42 65 ptg000023l:41882281-41883766 Q96AY4 1.55e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12494 FUN_033317 0 0 0 6 2 NA NA NA NA NA NA NA 12495 FUN_033312 0 13 0 0 1 NA NA NA NA NA NA NA 12496 FUN_033313 228 261 25 129 170 NA NA NA NA NA NA NA 12497 FUN_033310 3 44 0 0 7 NA NA NA NA NA NA NA 12498 FUN_033311 0 23 0 0 18 NA NA NA NA NA NA NA 12499 FUN_044196 0 0 11 10 23 NA NA NA NA NA NA NA 12500 FUN_043878 90 182 166 199 493 NA NA NA NA NA NA NA 12501 FUN_041966 18 0 11 27 47 NA NA NA NA NA NA NA 12502 FUN_032390 2816 2486 1352 2029 1609 NA NA NA NA NA NA NA 12503 FUN_013303 16 320 0 0 0 NA NA NA NA NA NA NA 12504 FUN_001039 38 633 93 328 171 NA NA NA NA NA NA NA 12505 FUN_013302 0 0 0 42 67 NA NA NA NA NA NA NA 12506 FUN_019641 0 27 0 0 5 NA NA NA NA NA NA NA 12507 FUN_016809 26 0 0 16 0 ptg000011l:7743177-7750500 Q9WTS8 1.49e-42 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 12508 FUN_016803 0 0 12 0 0 NA NA NA NA NA NA NA 12509 FUN_016802 0 0 0 17 12 NA NA NA NA NA NA NA 12510 FUN_016801 7 0 0 66 0 NA NA NA NA NA NA NA 12511 FUN_016800 84 61 38 113 77 NA NA NA NA NA NA NA 12512 FUN_016807 0 0 20 0 0 NA NA NA NA NA NA NA 12513 FUN_016804 0 17 0 13 227 NA NA NA NA NA NA NA 12514 FUN_002699 220 223 121 344 387 NA NA NA NA NA NA NA 12515 FUN_001031 687 1014 512 721 598 NA NA NA NA NA NA NA 12516 FUN_041968 522 325 339 395 362 ptg000035l:9423979-9433786 Q58DZ6 9.03e-25 Zinc finger protein 143 (Selenocysteine tRNA gene transcription-activating factor) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0003677; GO:0005634; GO:0046872 12517 FUN_041969 894 910 640 377 816 ptg000035l:9434320-9437088 Q66JG5 3.38e-97 Transcriptional adapter 3 (ADA3 homolog) (Transcriptional adapter 3-like) (ADA3-like protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005634 12518 FUN_008572 0 0 19 0 0 NA NA NA NA NA NA NA 12519 FUN_008573 0 51 0 59 0 ptg000002l:13011507-13014216 Q12955 1.26e-95 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 12520 FUN_008573 0 51 0 59 0 ptg000002l:13011507-13014216 Q12955 6.88e-83 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 12521 FUN_008573 0 51 0 59 0 ptg000002l:13011507-13014216 Q12955 7.63e-67 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 12522 FUN_008573 0 51 0 59 0 ptg000002l:13011507-13014216 Q12955 2e-44 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 12523 FUN_006518 354 145 59 535 120 NA NA NA NA NA NA NA 12524 FUN_006519 358 352 139 777 325 NA NA NA NA NA NA NA 12525 FUN_008576 3911 71 301 566 1159 NA NA NA NA NA NA NA 12526 FUN_008577 403 308 257 313 572 NA NA NA NA NA NA NA 12527 FUN_008578 688 427 246 555 434 NA NA NA NA NA NA NA 12528 FUN_008579 581 459 366 191 281 NA NA NA NA NA NA NA 12529 FUN_006512 640 74 162 376 43 NA NA NA NA NA NA NA 12530 FUN_006513 0 0 2 13 142 NA NA NA NA NA NA NA 12531 FUN_042899 31 0 0 0 0 ptg000047l:1464273-1464751 A0A0R4IBK5 3.29e-27 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 12532 FUN_042898 716 4939 382 2153 2617 NA NA NA NA NA NA NA 12533 FUN_042897 282 1767 99 1175 1076 NA NA NA NA NA NA NA 12534 FUN_042896 44 1223 0 526 689 NA NA NA NA NA NA NA 12535 FUN_042891 65 319 12 283 639 ptg000047l:1364811-1376253 A0A0R4IBK5 1.97e-26 E3 ubiquitin-protein ligase rnf213-alpha (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-alpha) (EC 2.3.2.-) (Mysterin-A) (Mysterin-alpha) (RING finger protein 213-A) (RING finger protein 213-alpha) Danio rerio (Zebrafish) (Brachydanio rerio) blood circulation [GO:0008015]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0008015; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 12536 FUN_042890 4 208 0 181 202 NA NA NA NA NA NA NA 12537 FUN_042892 137 2450 25 956 1449 ptg000047l:1377506-1407366 Q63HN8 2.35e-39 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 12538 FUN_040002 0 355 17 0 99 ptg000031l:2783094-2807561 Q04721 1.8e-25 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 12539 FUN_040002 0 355 17 0 99 ptg000031l:2783094-2807561 Q04721 1.8e-25 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 12540 FUN_040002 0 355 17 0 99 ptg000031l:2783094-2807561 Q04721 1.8e-25 Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)] Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; atrioventricular node development [GO:0003162]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cellular response to tumor cell [GO:0071228]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of apoptotic process [GO:0043066]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; wound healing [GO:0042060] GO:0000122; GO:0000139; GO:0001701; GO:0001709; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003162; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005789; GO:0005886; GO:0005929; GO:0006915; GO:0006959; GO:0007219; GO:0007399; GO:0007411; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0016020; GO:0019899; GO:0030097; GO:0030326; GO:0030509; GO:0030513; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043066; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0061314; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:1990705; GO:2000249; GO:2001204 12541 FUN_040004 4662 2852 1771 3102 1287 NA NA NA NA NA NA NA 12542 FUN_004603 109 220 488 851 316 ntLink_8:24773240-24789550 M9NDE3 8.44e-25 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 12543 FUN_004603 109 220 488 851 316 ntLink_8:24773240-24789550 M9NDE3 5.86e-22 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 12544 FUN_004601 1664 645 258 1146 709 ntLink_8:24746384-24753049 Q96AY4 1.09e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12545 FUN_004601 1664 645 258 1146 709 ntLink_8:24746384-24753049 Q96AY4 7.71e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12546 FUN_004601 1664 645 258 1146 709 ntLink_8:24746384-24753049 Q96AY4 1.65e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12547 FUN_004601 1664 645 258 1146 709 ntLink_8:24746384-24753049 Q96AY4 2.54e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12548 FUN_004601 1664 645 258 1146 709 ntLink_8:24746384-24753049 Q96AY4 2.23e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12549 FUN_004601 1664 645 258 1146 709 ntLink_8:24746384-24753049 Q96AY4 2.78e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12550 FUN_040008 6 0 0 12 10 NA NA NA NA NA NA NA 12551 FUN_040009 27 9 0 35 32 ptg000031l:2867441-2871182 P97633 1.8e-51 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Rattus norvegicus (Rat) cell cycle [GO:0007049]; cell division [GO:0051301]; cell morphogenesis [GO:0000902]; Golgi organization [GO:0007030]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein phosphorylation [GO:0006468]; regulation of GTP binding [GO:1904424]; response to morphine [GO:0043278]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0000287; GO:0000776; GO:0000902; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005829; GO:0006468; GO:0007030; GO:0007049; GO:0007165; GO:0016055; GO:0016607; GO:0018105; GO:0030877; GO:0032436; GO:0036064; GO:0042277; GO:0043278; GO:0045104; GO:0051219; GO:0051301; GO:0090090; GO:0106310; GO:1900226; GO:1904424; GO:1990904 12552 FUN_004608 478 498 708 1045 563 NA NA NA NA NA NA NA 12553 FUN_004609 328 6 22 4 81 NA NA NA NA NA NA NA 12554 FUN_007995 12533 7601 4692 10241 7203 ptg000002l:6975803-6993734 Q91048 4.38e-47 Inactive tyrosine-protein kinase 7 (Kinase-like protein) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7) Gallus gallus (Chicken) cell adhesion [GO:0007155]; regulation of canonical Wnt signaling pathway [GO:0060828]; Wnt signaling pathway [GO:0016055] GO:0004713; GO:0005524; GO:0005886; GO:0005911; GO:0007155; GO:0016055; GO:0050839; GO:0060828 12555 FUN_032958 1371 731 514 1004 664 NA NA NA NA NA NA NA 12556 FUN_032957 0 0 2 48 80 NA NA NA NA NA NA NA 12557 FUN_032956 12 2 33 83 13 ptg000023l:38093226-38096453 Q96AY4 1.6e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12558 FUN_032956 12 2 33 83 13 ptg000023l:38093226-38096453 Q96AY4 1.21e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12559 FUN_032956 12 2 33 83 13 ptg000023l:38093226-38096453 Q96AY4 1.1e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12560 FUN_032956 12 2 33 83 13 ptg000023l:38093226-38096453 Q96AY4 8.67e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12561 FUN_032956 12 2 33 83 13 ptg000023l:38093226-38096453 Q96AY4 1.67e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12562 FUN_032956 12 2 33 83 13 ptg000023l:38093226-38096453 Q96AY4 2.02e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12563 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 1.12e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12564 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 1.21e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12565 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 3.78e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12566 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 9.3e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12567 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 2.13e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12568 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 1.56e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12569 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 1.23e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12570 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 5.44e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12571 FUN_032955 4 0 0 98 92 ptg000023l:38078508-38085364 Q96AY4 5.55e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12572 FUN_032954 69 26 9 204 52 NA NA NA NA NA NA NA 12573 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 1.75e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12574 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 5.36e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12575 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 8.24e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12576 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 6.01e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12577 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 1.76e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12578 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 1.43e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12579 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 3.34e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12580 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 6.11e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12581 FUN_032953 125 17 12 427 299 ptg000023l:38056622-38067559 Q96AY4 1.19e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12582 FUN_032952 15 0 0 78 17 ptg000023l:38023643-38028838 Q96AY4 1.14e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12583 FUN_032952 15 0 0 78 17 ptg000023l:38023643-38028838 Q96AY4 5.1e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12584 FUN_032952 15 0 0 78 17 ptg000023l:38023643-38028838 Q96AY4 3.5e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12585 FUN_032952 15 0 0 78 17 ptg000023l:38023643-38028838 Q96AY4 4.51e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12586 FUN_032952 15 0 0 78 17 ptg000023l:38023643-38028838 Q96AY4 1.41e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12587 FUN_043228 640 359 150 108 200 ptg000047l:5642643-5646645 Q96AY4 1.29e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12588 FUN_043228 640 359 150 108 200 ptg000047l:5642643-5646645 Q96AY4 2.6e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12589 FUN_043228 640 359 150 108 200 ptg000047l:5642643-5646645 Q96AY4 1.55e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12590 FUN_043228 640 359 150 108 200 ptg000047l:5642643-5646645 Q96AY4 7.76e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12591 FUN_014596 230 176 83 265 201 ptg000009l:1389064-1391289 Q05B89 1.14e-47 NIF3-like protein 1 Bos taurus (Bovine) negative regulation of nucleic acid-templated transcription [GO:1903507]; neuron differentiation [GO:0030182] GO:0005634; GO:0005737; GO:0005739; GO:0030182; GO:1903507 12592 FUN_014596 230 176 83 265 201 ptg000009l:1389064-1391289 Q05B89 1.55e-43 NIF3-like protein 1 Bos taurus (Bovine) negative regulation of nucleic acid-templated transcription [GO:1903507]; neuron differentiation [GO:0030182] GO:0005634; GO:0005737; GO:0005739; GO:0030182; GO:1903507 12593 FUN_009515 1520 2288 663 1454 799 NA NA NA NA NA NA NA 12594 FUN_008517 4847 3406 2318 4316 3690 NA NA NA NA NA NA NA 12595 FUN_002525 495 36 228 188 168 NA NA NA NA NA NA NA 12596 FUN_002524 346 172 72 141 103 NA NA NA NA NA NA NA 12597 FUN_002527 3332 226 353 3231 1244 NA NA NA NA NA NA NA 12598 FUN_002521 0 0 6 0 0 NA NA NA NA NA NA NA 12599 FUN_011056 755 1284 864 1491 967 ptg000007l:5941642-5943223 P54965 5.21e-30 Conjugated bile acid hydrolase (CBAH) (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (CBAH-1) (Choloylglycine hydrolase) (EC 3.5.1.24) Clostridium perfringens (strain 13 / Type A) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 12600 FUN_011059 8771 3501 6045 2346 1834 NA NA NA NA NA NA NA 12601 FUN_011058 441 172 295 208 173 ptg000007l:5951766-5954187 P57772 2.63e-149 Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) Homo sapiens (Human) selenocysteine incorporation [GO:0001514]; translational elongation [GO:0006414] GO:0000049; GO:0001514; GO:0003746; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0006414; GO:0035368; GO:0043021; GO:1990904 12602 FUN_011058 441 172 295 208 173 ptg000007l:5951766-5954187 P57772 3.15e-53 Selenocysteine-specific elongation factor (Elongation factor sec) (Eukaryotic elongation factor, selenocysteine-tRNA-specific) Homo sapiens (Human) selenocysteine incorporation [GO:0001514]; translational elongation [GO:0006414] GO:0000049; GO:0001514; GO:0003746; GO:0003924; GO:0005525; GO:0005634; GO:0005737; GO:0006414; GO:0035368; GO:0043021; GO:1990904 12603 FUN_002529 2019 107 668 470 405 NA NA NA NA NA NA NA 12604 FUN_009514 14115 8384 6866 14937 9697 ptg000004l:7924735-7930200 B7W112 1.64e-99 Aspartic and glutamic acid-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 12605 FUN_009514 14115 8384 6866 14937 9697 ptg000004l:7924735-7930200 B7W112 2.85e-35 Aspartic and glutamic acid-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 12606 FUN_009514 14115 8384 6866 14937 9697 ptg000004l:7924735-7930200 B7W112 2.85e-35 Aspartic and glutamic acid-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 12607 FUN_011580 942 769 8 722 628 NA NA NA NA NA NA NA 12608 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 9.44e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12609 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 1.33e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12610 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 1.01e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12611 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 1.28e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12612 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 6.08e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12613 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 1.03e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12614 FUN_000602 379 304 1118 1924 271 ntLink_6:4865185-4869264 Q7RTR2 7.9e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12615 FUN_000603 577 0 0 132 0 ntLink_6:4895883-4900196 Q7RTR2 8.26e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12616 FUN_000603 577 0 0 132 0 ntLink_6:4895883-4900196 Q7RTR2 7.07e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12617 FUN_000603 577 0 0 132 0 ntLink_6:4895883-4900196 Q7RTR2 2.31e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12618 FUN_000600 383 0 488 78 5 ntLink_6:4834719-4841203 Q7RTR2 3.32e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12619 FUN_000600 383 0 488 78 5 ntLink_6:4834719-4841203 Q7RTR2 4.53e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12620 FUN_000600 383 0 488 78 5 ntLink_6:4834719-4841203 Q7RTR2 4.57e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12621 FUN_000600 383 0 488 78 5 ntLink_6:4834719-4841203 Q7RTR2 8.71e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12622 FUN_000600 383 0 488 78 5 ntLink_6:4834719-4841203 Q7RTR2 6.92e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 12623 FUN_000606 238 340 177 532 292 ntLink_6:4938182-4940713 Q96LT4 1.51e-51 Sphingomyelin synthase-related protein 1 (SMSr) (EC 2.7.8.-) (Ceramide phosphoethanolamine synthase) (CPE synthase) (Sterile alpha motif domain-containing protein 8) (SAM domain-containing protein 8) Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; ceramide phosphoethanolamine biosynthetic process [GO:1905373]; regulation of ceramide biosynthetic process [GO:2000303]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686] GO:0000139; GO:0002950; GO:0005783; GO:0005789; GO:0005829; GO:0005886; GO:0006686; GO:0016020; GO:0030148; GO:0033188; GO:0046513; GO:0047493; GO:1905373; GO:2000303 12624 FUN_000607 2533 2423 1591 2493 3001 NA NA NA NA NA NA NA 12625 FUN_029289 149 65 55 33 47 NA NA NA NA NA NA NA 12626 FUN_000605 13 964 304 612 669 NA NA NA NA NA NA NA 12627 FUN_029287 0 0 0 25 0 NA NA NA NA NA NA NA 12628 FUN_029286 582 816 434 331 243 NA NA NA NA NA NA NA 12629 FUN_029285 5 9 8 0 3 NA NA NA NA NA NA NA 12630 FUN_029284 150 30 59 89 113 NA NA NA NA NA NA NA 12631 FUN_029283 968 527 542 2319 776 ptg000023l:36127-38159 P22770 1.24e-22 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 12632 FUN_029282 94 70 125 386 129 NA NA NA NA NA NA NA 12633 FUN_029281 0 0 17 7 5 NA NA NA NA NA NA NA 12634 FUN_002555 1033 0 133 1067 51 ntLink_8:3573903-3607962 Q8R151 1.93e-89 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 12635 FUN_002555 1033 0 133 1067 51 ntLink_8:3573903-3607962 Q8R151 1.85e-68 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 12636 FUN_002555 1033 0 133 1067 51 ntLink_8:3573903-3607962 Q8R151 5.12e-42 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 12637 FUN_002555 1033 0 133 1067 51 ntLink_8:3573903-3607962 Q8R151 1.62e-33 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 12638 FUN_005177 3798 2396 1412 3285 2560 ntLink_8:32200567-32227875 A6H8H2 6.91e-21 DENN domain-containing protein 4C Mus musculus (Mouse) cellular response to insulin stimulus [GO:0032869]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005794; GO:0005829; GO:0005886; GO:0015031; GO:0030659; GO:0030904; GO:0031410; GO:0032483; GO:0032593; GO:0032869; GO:0043231; GO:0072659 12639 FUN_044222 7 5 14 3 115 NA NA NA NA NA NA NA 12640 FUN_041738 4715 2609 2177 3068 2353 ptg000035l:6973644-6977545 Q6L9W6 1.16e-39 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 12641 FUN_041738 4715 2609 2177 3068 2353 ptg000035l:6973644-6977545 Q6L9W6 1.79e-28 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 12642 FUN_030177 36 2082 47 5809 1837 NA NA NA NA NA NA NA 12643 FUN_005174 1289 997 495 742 855 NA NA NA NA NA NA NA 12644 FUN_044225 0 0 3 0 22 NA NA NA NA NA NA NA 12645 FUN_044226 41 145 69 115 380 NA NA NA NA NA NA NA 12646 FUN_044227 4 2 13 2 104 NA NA NA NA NA NA NA 12647 FUN_041737 769 551 378 504 468 NA NA NA NA NA NA NA 12648 FUN_003956 0 0 0 0 18 NA NA NA NA NA NA NA 12649 FUN_041736 58 73 15 63 93 ptg000035l:6948653-6952706 Q8K0U4 1.68e-58 Heat shock 70 kDa protein 12A Mus musculus (Mouse) NA GO:0005524; GO:0005634; GO:0005737 12650 FUN_016586 1158 734 663 866 759 NA NA NA NA NA NA NA 12651 FUN_016587 599 367 355 536 354 ptg000011l:5040886-5050166 Q0DXS3 1.87e-67 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 12652 FUN_016582 19 45 52 19 50 ptg000011l:4974221-4981402 Q8IZU8 2.7e-179 Dermatan-sulfate epimerase-like protein (EC 5.1.-.-) Homo sapiens (Human) chondroitin sulfate metabolic process [GO:0030204]; dermatan sulfate biosynthetic process [GO:0030208]; dermatan sulfate metabolic process [GO:0030205] GO:0000139; GO:0008146; GO:0030204; GO:0030205; GO:0030208; GO:0047757 12653 FUN_016583 240 196 197 307 153 NA NA NA NA NA NA NA 12654 FUN_016580 1436 628 362 580 984 NA NA NA NA NA NA NA 12655 FUN_016581 7 31 4 12 0 ptg000011l:4968518-4970730 Q9JME2 6.01e-34 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 12656 FUN_013563 0 0 0 24 56 NA NA NA NA NA NA NA 12657 FUN_013562 10 8 23 55 17 NA NA NA NA NA NA NA 12658 FUN_013561 2096 1244 676 1379 1136 NA NA NA NA NA NA NA 12659 FUN_013560 2277 3448 1326 2080 1790 NA NA NA NA NA NA NA 12660 FUN_013567 13 0 0 15 83 NA NA NA NA NA NA NA 12661 FUN_016588 3305 2204 1936 1237 1422 NA NA NA NA NA NA NA 12662 FUN_016589 1335 876 502 1077 1023 NA NA NA NA NA NA NA 12663 FUN_018506 3713 489 590 1298 1890 NA NA NA NA NA NA NA 12664 FUN_041196 5 1 9 0 16 NA NA NA NA NA NA NA 12665 FUN_038369 0 8 0 0 6 NA NA NA NA NA NA NA 12666 FUN_016059 5 5 29 0 31 NA NA NA NA NA NA NA 12667 FUN_016050 36 270 218 320 0 ptg000010l:1049619-1051001 Q9WU63 7.81e-21 Heme-binding protein 2 (Protein SOUL) Mus musculus (Mouse) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035794 12668 FUN_042331 42 9 42 87 127 NA NA NA NA NA NA NA 12669 FUN_016052 37 56 42 61 20 NA NA NA NA NA NA NA 12670 FUN_042333 103 40 67 58 108 ptg000036l:3940989-3954573 O00370 3.43e-23 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 12671 FUN_016054 92 70 29 66 76 NA NA NA NA NA NA NA 12672 FUN_016055 2914 1706 1201 3397 2364 NA NA NA NA NA NA NA 12673 FUN_042336 37 0 136 19 334 NA NA NA NA NA NA NA 12674 FUN_042337 0 25 53 0 14 NA NA NA NA NA NA NA 12675 FUN_013698 0 0 0 0 38 NA NA NA NA NA NA NA 12676 FUN_013695 0 0 0 19 0 NA NA NA NA NA NA NA 12677 FUN_013694 33 0 0 31 0 NA NA NA NA NA NA NA 12678 FUN_013697 0 20 0 7 5 NA NA NA NA NA NA NA 12679 FUN_013691 0 0 43 0 178 NA NA NA NA NA NA NA 12680 FUN_013693 0 0 8 2 68 NA NA NA NA NA NA NA 12681 FUN_015592 7 0 0 0 4 NA NA NA NA NA NA NA 12682 FUN_015599 3 8 0 0 4 NA NA NA NA NA NA NA 12683 FUN_008969 730 617 318 817 646 ptg000004l:966030-968107 Q54SR7 4.72e-24 FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Dictyostelium discoideum (Social amoeba) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005783; GO:0061077 12684 FUN_008968 1104 643 405 638 571 NA NA NA NA NA NA NA 12685 FUN_008963 237 228 66 188 272 ptg000004l:919000-919969 P49286 1.81e-25 Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Homo sapiens (Human) camera-type eye development [GO:0043010]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transmission of nerve impulse [GO:0051970]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of insulin secretion [GO:0050796]; regulation of neuronal action potential [GO:0098908] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007268; GO:0008502; GO:0010754; GO:0042593; GO:0043010; GO:0043524; GO:0045202; GO:0045906; GO:0046010; GO:0046676; GO:0050796; GO:0051481; GO:0051970; GO:0051971; GO:0098908; GO:1902260 12686 FUN_008962 1890 911 1517 2509 1981 NA NA NA NA NA NA NA 12687 FUN_008961 953 1181 544 1373 975 NA NA NA NA NA NA NA 12688 FUN_008960 1148 665 473 983 866 NA NA NA NA NA NA NA 12689 FUN_008967 934 705 453 554 692 NA NA NA NA NA NA NA 12690 FUN_008966 51 26 17 58 13 NA NA NA NA NA NA NA 12691 FUN_008965 1624 1572 645 699 571 NA NA NA NA NA NA NA 12692 FUN_008964 1122 786 667 940 890 NA NA NA NA NA NA NA 12693 FUN_023634 7727 4434 3567 5868 5041 NA NA NA NA NA NA NA 12694 FUN_028627 0 0 7 30 79 NA NA NA NA NA NA NA 12695 FUN_023636 6319 6552 3610 3474 1973 NA NA NA NA NA NA NA 12696 FUN_028622 36 0 200 128 43 NA NA NA NA NA NA NA 12697 FUN_028623 37 12 0 33 23 ptg000022l:1631830-1636863 Q96AY4 3.18e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12698 FUN_028623 37 12 0 33 23 ptg000022l:1631830-1636863 Q96AY4 2.44e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12699 FUN_028623 37 12 0 33 23 ptg000022l:1631830-1636863 Q96AY4 6.93e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12700 FUN_028623 37 12 0 33 23 ptg000022l:1631830-1636863 Q96AY4 1.75e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12701 FUN_028623 37 12 0 33 23 ptg000022l:1631830-1636863 Q96AY4 3.87e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12702 FUN_023632 5401 3670 2384 2465 1522 NA NA NA NA NA NA NA 12703 FUN_028621 14 12 22 16 19 NA NA NA NA NA NA NA 12704 FUN_023638 501 331 268 1337 462 NA NA NA NA NA NA NA 12705 FUN_023639 39922 43852 15865 27721 16852 NA NA NA NA NA NA NA 12706 FUN_028629 0 75 47 3 172 NA NA NA NA NA NA NA 12707 FUN_039866 87 63 62 108 100 NA NA NA NA NA NA NA 12708 FUN_018507 111 47 50 201 315 NA NA NA NA NA NA NA 12709 FUN_019017 849 311 165 407 191 ptg000012l:16317129-16339064 P08548 1.83e-37 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 12710 FUN_041159 471 20 141 373 39 NA NA NA NA NA NA NA 12711 FUN_041158 1853 214 1593 805 742 ptg000034l:2890146-2905526 A0A1B4XBH3 1.98e-148 Highly reducing polyketide synthase sdnO (EC 2.3.1.-) (Sordarin/hypoxysordarin biosynthesis cluster protein O) Sordaria araneosa (Pleurage araneosa) antibiotic biosynthetic process [GO:0017000]; organic substance biosynthetic process [GO:1901576] GO:0016491; GO:0016746; GO:0017000; GO:0031177; GO:1901576 12712 FUN_041150 2 0 15 0 107 NA NA NA NA NA NA NA 12713 FUN_041155 123 35 415 159 92 ptg000034l:2855304-2859965 Q0EEE2 5.55e-56 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 12714 FUN_041157 20 3 4 13 18 NA NA NA NA NA NA NA 12715 FUN_041156 9 0 0 4 0 NA NA NA NA NA NA NA 12716 FUN_014655 211 183 95 312 300 NA NA NA NA NA NA NA 12717 FUN_009519 6689 5991 4272 4371 4458 ptg000004l:7953386-7964783 P13630 4.81e-30 Histone H2A Paracentrotus lividus (Common sea urchin) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 12718 FUN_011873 785 176 240 375 645 ptg000008l:2299772-2317143 Q9ESJ0 1.42e-23 Exportin-4 (Exp4) Mus musculus (Mouse) positive regulation of protein export from nucleus [GO:0046827]; protein export from nucleus [GO:0006611] GO:0005049; GO:0005643; GO:0005654; GO:0005737; GO:0005829; GO:0006611; GO:0046827 12719 FUN_011872 145 365 297 210 364 NA NA NA NA NA NA NA 12720 FUN_011871 821 721 652 874 1051 ptg000008l:2283694-2289622 E9PXX9 1.68e-33 Sodium/nucleoside cotransporter 1 (Concentrative nucleoside transporter 1) (CNT 1) (Na(+)/nucleoside cotransporter 1) (Sodium-coupled nucleoside transporter 1) (Solute carrier family 28 member 1) Mus musculus (Mouse) azole transmembrane transport [GO:0045117]; cytidine transport [GO:0015861]; nucleoside transmembrane transport [GO:1901642]; pyrimidine nucleobase transport [GO:0015855]; pyrimidine-containing compound transmembrane transport [GO:0072531]; uridine transport [GO:0015862] GO:0005337; GO:0005350; GO:0005415; GO:0005829; GO:0005886; GO:0015212; GO:0015213; GO:0015293; GO:0015389; GO:0015855; GO:0015861; GO:0015862; GO:0016020; GO:0016324; GO:0016607; GO:0031526; GO:0045117; GO:0072531; GO:1901474; GO:1901642 12721 FUN_011870 5995 4134 2108 3707 1982 ptg000008l:2270240-2282397 Q9QXE2 7.38e-137 DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase kappa) Mus musculus (Mouse) base-excision repair, gap-filling [GO:0006287]; DNA biosynthetic process [GO:0071897]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; nucleotide-excision repair [GO:0006289] GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005654; GO:0006260; GO:0006287; GO:0006289; GO:0006303; GO:0035861; GO:0046872; GO:0051575; GO:0071897 12722 FUN_011877 7 95 32 0 0 NA NA NA NA NA NA NA 12723 FUN_011876 1310 1404 937 1099 647 ptg000008l:2333313-2338233 Q9C0D7 2.99e-64 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 12724 FUN_011875 1677 1809 897 1406 1071 NA NA NA NA NA NA NA 12725 FUN_011874 580 621 435 751 519 NA NA NA NA NA NA NA 12726 FUN_011879 390 35 55 126 0 NA NA NA NA NA NA NA 12727 FUN_011878 219 310 74 229 3 ptg000008l:2380157-2381099 Q5ZID0 1.06e-27 NmrA-like family domain-containing protein 1 Gallus gallus (Chicken) NA GO:0005634; GO:0048471 12728 FUN_032998 133 19 14 179 40 ptg000023l:38685146-38694033 P0C6B8 2.24e-22 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 Rattus norvegicus (Rat) cell adhesion [GO:0007155]; epidermis development [GO:0008544]; gene expression [GO:0010467]; lymph circulation [GO:0003017]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; Tie signaling pathway [GO:0048014]; tight junction organization [GO:0120193] GO:0001945; GO:0003017; GO:0003682; GO:0005509; GO:0005615; GO:0005634; GO:0005737; GO:0007155; GO:0008544; GO:0010467; GO:0016020; GO:0031012; GO:0036303; GO:0048014; GO:0120193 12729 FUN_009518 506 294 211 483 497 NA NA NA NA NA NA NA 12730 FUN_000630 49 85 237 69 25 NA NA NA NA NA NA NA 12731 FUN_025779 2701 3041 1766 2855 2710 NA NA NA NA NA NA NA 12732 FUN_025778 1364 1797 1755 1765 1353 NA NA NA NA NA NA NA 12733 FUN_025773 118 30 54 89 149 ptg000020l:610061-611387 O94323 4.57e-24 Uncharacterized pyrophosphatase/phosphodiesterase C725.05c (EC 3.-.-.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) nucleoside triphosphate metabolic process [GO:0009141] GO:0004551; GO:0009141; GO:0016020; GO:0017111; GO:0047429 12734 FUN_025773 118 30 54 89 149 ptg000020l:610061-611387 O94323 4.57e-24 Uncharacterized pyrophosphatase/phosphodiesterase C725.05c (EC 3.-.-.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) nucleoside triphosphate metabolic process [GO:0009141] GO:0004551; GO:0009141; GO:0016020; GO:0017111; GO:0047429 12735 FUN_025772 128 75 70 115 196 NA NA NA NA NA NA NA 12736 FUN_025771 165 275 211 172 159 NA NA NA NA NA NA NA 12737 FUN_025770 300 190 166 361 315 NA NA NA NA NA NA NA 12738 FUN_025777 5753 6296 2122 4342 2158 NA NA NA NA NA NA NA 12739 FUN_025776 1202 340 380 631 457 NA NA NA NA NA NA NA 12740 FUN_025775 24087 22343 11325 21620 11427 NA NA NA NA NA NA NA 12741 FUN_025774 433 218 720 554 254 NA NA NA NA NA NA NA 12742 FUN_008039 106 73 46 42 52 NA NA NA NA NA NA NA 12743 FUN_008038 230 176 68 156 217 NA NA NA NA NA NA NA 12744 FUN_008031 563 557 36 613 474 NA NA NA NA NA NA NA 12745 FUN_008030 90 179 84 206 114 NA NA NA NA NA NA NA 12746 FUN_008033 222 499 20 274 381 NA NA NA NA NA NA NA 12747 FUN_008032 276 151 89 271 227 NA NA NA NA NA NA NA 12748 FUN_008035 1540 986 760 932 800 NA NA NA NA NA NA NA 12749 FUN_008034 57 43 8 141 71 NA NA NA NA NA NA NA 12750 FUN_008037 221 164 192 155 352 ptg000002l:7415407-7420863 Q9NVM6 1.46e-23 DnaJ homolog subfamily C member 17 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; spliceosomal complex disassembly [GO:0000390]; toxin transport [GO:1901998] GO:0000122; GO:0000390; GO:0003723; GO:0005681; GO:0005737; GO:1901998 12751 FUN_008036 46 48 106 78 142 ptg000002l:7412717-7415329 Q9Z186 1.21e-23 Glucose-6-phosphatase 2 (G-6-Pase 2) (G6Pase 2) (EC 3.1.3.9) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein) Mus musculus (Mouse) gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; regulation of insulin secretion [GO:0050796] GO:0005783; GO:0005789; GO:0006094; GO:0016020; GO:0016787; GO:0042593; GO:0050796; GO:0051156 12752 FUN_014344 0 16 0 0 0 NA NA NA NA NA NA NA 12753 FUN_044060 22 14 6 2 35 NA NA NA NA NA NA NA 12754 FUN_022279 1585 1403 1272 1356 826 ptg000016l:7123131-7136994 Q7ZWS1 3.09e-28 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like (EC 1.3.1.89) (mRNA-dihydrouridine synthase DUS3L) (EC 1.3.1.-) (tRNA-dihydrouridine synthase 3-like) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; regulation of translation [GO:0006417]; tRNA dihydrouridine synthesis [GO:0002943] GO:0002943; GO:0006397; GO:0006417; GO:0017150; GO:0046872; GO:0050660 12755 FUN_022278 4611 3352 1841 3946 3255 NA NA NA NA NA NA NA 12756 FUN_022277 0 0 2 24 8 NA NA NA NA NA NA NA 12757 FUN_022276 378 471 329 386 718 NA NA NA NA NA NA NA 12758 FUN_022275 1096 960 586 1129 886 NA NA NA NA NA NA NA 12759 FUN_022274 149 125 62 170 99 NA NA NA NA NA NA NA 12760 FUN_022273 0 0 0 0 6 NA NA NA NA NA NA NA 12761 FUN_022272 1861 1990 101 421 2302 ptg000016l:7078718-7089800 Q8K3Z0 1.32e-40 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 12762 FUN_022271 1563 1450 1263 1769 2059 NA NA NA NA NA NA NA 12763 FUN_022270 1245 1248 544 799 879 NA NA NA NA NA NA NA 12764 FUN_014968 561 483 308 479 365 NA NA NA NA NA NA NA 12765 FUN_014969 1449 1249 838 1431 1347 NA NA NA NA NA NA NA 12766 FUN_014962 813 875 581 811 672 NA NA NA NA NA NA NA 12767 FUN_014963 880 712 552 598 486 NA NA NA NA NA NA NA 12768 FUN_014960 9 62 46 31 31 NA NA NA NA NA NA NA 12769 FUN_014961 105 1223 333 460 144 ptg000009l:4779669-4780308 Q9Y5Z4 4.96e-27 Heme-binding protein 2 (Placental protein 23) (PP23) (Protein SOUL) Homo sapiens (Human) negative regulation of mitochondrial membrane potential [GO:0010917]; positive regulation of mitochondrial membrane permeability [GO:0035794]; positive regulation of necrotic cell death [GO:0010940] GO:0005576; GO:0005737; GO:0005739; GO:0010917; GO:0010940; GO:0020037; GO:0035578; GO:0035794; GO:0070062 12770 FUN_014966 1692 993 1267 2144 1334 NA NA NA NA NA NA NA 12771 FUN_014967 2070 1681 902 1580 1740 NA NA NA NA NA NA NA 12772 FUN_014964 7073 4732 3827 6496 6649 ptg000009l:4793854-4800096 A7S338 3.67e-47 Lissencephaly-1 homolog Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; microtubule sliding [GO:0051012]; nuclear migration [GO:0007097]; vesicle transport along microtubule [GO:0047496] GO:0000132; GO:0000776; GO:0005635; GO:0005815; GO:0005875; GO:0005881; GO:0007097; GO:0031023; GO:0047496; GO:0051010; GO:0051012; GO:0051301; GO:0070840 12773 FUN_014964 7073 4732 3827 6496 6649 ptg000009l:4793854-4800096 A7S338 3.67e-47 Lissencephaly-1 homolog Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; microtubule sliding [GO:0051012]; nuclear migration [GO:0007097]; vesicle transport along microtubule [GO:0047496] GO:0000132; GO:0000776; GO:0005635; GO:0005815; GO:0005875; GO:0005881; GO:0007097; GO:0031023; GO:0047496; GO:0051010; GO:0051012; GO:0051301; GO:0070840 12774 FUN_014964 7073 4732 3827 6496 6649 ptg000009l:4793854-4800096 A7S338 1.99e-23 Lissencephaly-1 homolog Nematostella vectensis (Starlet sea anemone) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; microtubule organizing center organization [GO:0031023]; microtubule sliding [GO:0051012]; nuclear migration [GO:0007097]; vesicle transport along microtubule [GO:0047496] GO:0000132; GO:0000776; GO:0005635; GO:0005815; GO:0005875; GO:0005881; GO:0007097; GO:0031023; GO:0047496; GO:0051010; GO:0051012; GO:0051301; GO:0070840 12775 FUN_014965 1758 2369 1307 2884 1488 ptg000009l:4802267-4829446 P14381 4.42e-97 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 12776 FUN_014965 1758 2369 1307 2884 1488 ptg000009l:4802267-4829446 P14381 4.42e-97 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 12777 FUN_038788 83 51 87 173 79 NA NA NA NA NA NA NA 12778 FUN_038789 112 55 83 144 134 NA NA NA NA NA NA NA 12779 FUN_038780 0 0 29 6 136 ptg000027l:11324219-11356005 O15439 8.51e-90 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12780 FUN_038780 0 0 29 6 136 ptg000027l:11324219-11356005 O15439 2.3e-89 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12781 FUN_038780 0 0 29 6 136 ptg000027l:11324219-11356005 O15439 1.22e-67 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12782 FUN_038780 0 0 29 6 136 ptg000027l:11324219-11356005 O15439 4.17e-32 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12783 FUN_038780 0 0 29 6 136 ptg000027l:11324219-11356005 O15439 4.21e-29 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12784 FUN_038782 23 29 22 12 15 ptg000027l:11367637-11377499 O15439 5.7e-89 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12785 FUN_038782 23 29 22 12 15 ptg000027l:11367637-11377499 O15439 2.46e-68 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12786 FUN_038782 23 29 22 12 15 ptg000027l:11367637-11377499 O15439 1.99e-33 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12787 FUN_038783 177 182 144 291 140 ptg000027l:11391264-11392308 F1R332 5.29e-28 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 12788 FUN_038784 8419 9181 6162 6991 5098 ptg000027l:11403144-11407678 O70454 3.56e-27 Protein BUD31 homolog (Protein EDG-2) (Protein G10 homolog) Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of androgen receptor activity [GO:2000825] GO:0000398; GO:0000785; GO:0005634; GO:0005681; GO:0016922; GO:0030374; GO:0071007; GO:2000825 12789 FUN_038785 9 0 6 0 16 NA NA NA NA NA NA NA 12790 FUN_038786 2330 1460 1112 1919 1741 NA NA NA NA NA NA NA 12791 FUN_038787 1190 2227 634 973 910 NA NA NA NA NA NA NA 12792 FUN_036905 132 81 76 317 151 ptg000026l:3290015-3297734 O15439 2.86e-68 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12793 FUN_036905 132 81 76 317 151 ptg000026l:3290015-3297734 O15439 2.23e-62 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12794 FUN_036905 132 81 76 317 151 ptg000026l:3290015-3297734 O15439 8.45e-34 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 12795 FUN_031175 0 0 0 0 8 NA NA NA NA NA NA NA 12796 FUN_031176 2266 807 1014 2107 2178 NA NA NA NA NA NA NA 12797 FUN_031177 20 0 1 0 38 NA NA NA NA NA NA NA 12798 FUN_031179 3428 3462 2162 3681 2789 NA NA NA NA NA NA NA 12799 FUN_039787 487 581 64 63 48 ptg000031l:159468-161755 Q7L1S5 7.17e-41 Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2) Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan metabolic process [GO:0030203]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001537; GO:0005576; GO:0006790; GO:0008146; GO:0016020; GO:0016051; GO:0030166; GO:0030203; GO:0030206; GO:0042446; GO:0047756 12800 FUN_039786 559 853 177 84 23 ptg000031l:143225-151113 Q7L1S5 5.76e-40 Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2) Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan metabolic process [GO:0030203]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001537; GO:0005576; GO:0006790; GO:0008146; GO:0016020; GO:0016051; GO:0030166; GO:0030203; GO:0030206; GO:0042446; GO:0047756 12801 FUN_039786 559 853 177 84 23 ptg000031l:143225-151113 Q7L1S5 8.21e-39 Carbohydrate sulfotransferase 9 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 2) (GalNAc-4-ST2) (GalNAc4ST-2) (N-acetylgalactosamine-4-O-sulfotransferase 2) Homo sapiens (Human) carbohydrate biosynthetic process [GO:0016051]; chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan metabolic process [GO:0030203]; hormone biosynthetic process [GO:0042446]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001537; GO:0005576; GO:0006790; GO:0008146; GO:0016020; GO:0016051; GO:0030166; GO:0030203; GO:0030206; GO:0042446; GO:0047756 12802 FUN_039783 397 531 124 51 35 ptg000031l:134254-138222 Q8BQ86 1.82e-39 Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1) (N-acetylgalactosamine-4-O-sulfotransferase 1) Mus musculus (Mouse) carbohydrate biosynthetic process [GO:0016051]; hormone biosynthetic process [GO:0042446]; peptide hormone processing [GO:0016486]; proteoglycan biosynthetic process [GO:0030166]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001537; GO:0006790; GO:0008146; GO:0016051; GO:0016486; GO:0030166; GO:0042446 12803 FUN_039782 739 1076 278 42 28 ptg000031l:124199-128954 Q805E5 1.93e-34 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 12804 FUN_039781 59 45 0 0 60 NA NA NA NA NA NA NA 12805 FUN_039780 13 207 95 55 258 ptg000031l:102141-104232 P69478 4.38e-40 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 12806 FUN_039789 1375 1268 1085 1976 1502 NA NA NA NA NA NA NA 12807 FUN_039788 0 0 0 13 39 NA NA NA NA NA NA NA 12808 FUN_037435 46 172 121 162 60 NA NA NA NA NA NA NA 12809 FUN_037433 132 59 0 93 27 NA NA NA NA NA NA NA 12810 FUN_037432 0 0 3 13 19 NA NA NA NA NA NA NA 12811 FUN_037431 74 12 38 67 60 NA NA NA NA NA NA NA 12812 FUN_037430 2411 1777 2040 5055 2893 NA NA NA NA NA NA NA 12813 FUN_027380 0 0 9 1 0 NA NA NA NA NA NA NA 12814 FUN_027381 20 133 16 0 6 NA NA NA NA NA NA NA 12815 FUN_027382 0 0 0 24 3 NA NA NA NA NA NA NA 12816 FUN_027383 0 342 12 2 2 NA NA NA NA NA NA NA 12817 FUN_027385 0 188 12 0 2 NA NA NA NA NA NA NA 12818 FUN_037439 6128 4409 4159 6067 4658 ptg000026l:10422558-10454748 P97393 1.82e-129 Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B) Mus musculus (Mouse) cell migration [GO:0016477]; epithelial cell migration [GO:0010631]; mammary gland development [GO:0030879]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of mesenchymal cell proliferation [GO:0002053]; regulation of cell size [GO:0008361]; Rho protein signal transduction [GO:0007266] GO:0002053; GO:0003924; GO:0005096; GO:0005525; GO:0005783; GO:0005829; GO:0005886; GO:0007266; GO:0008361; GO:0010631; GO:0010634; GO:0016477; GO:0030879; GO:0042169 12819 FUN_027387 0 7 13 5 0 NA NA NA NA NA NA NA 12820 FUN_005716 0 0 19 25 0 NA NA NA NA NA NA NA 12821 FUN_005714 0 6 14 0 6 NA NA NA NA NA NA NA 12822 FUN_005710 15 0 0 0 79 NA NA NA NA NA NA NA 12823 FUN_016066 27 18 10 41 0 NA NA NA NA NA NA NA 12824 FUN_005718 527 611 482 485 566 ptg000001l:3021906-3028590 P14381 1.03e-48 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 12825 FUN_001407 1370 1716 904 997 1138 NA NA NA NA NA NA NA 12826 FUN_001406 711 757 399 796 598 ntLink_6:11989523-11992102 Q91584 5.32e-70 ELAV-like protein 3 (Protein ElrC) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003723; GO:0007399; GO:0030154; GO:1990904 12827 FUN_001405 1384 817 634 742 575 NA NA NA NA NA NA NA 12828 FUN_001404 616 280 265 342 269 ntLink_6:11977149-11978610 Q556Y8 7.57e-33 Probable rhodanese domain-containing dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48) Dictyostelium discoideum (Social amoeba) negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470]; response to cisplatin [GO:0072718]; sorocarp development [GO:0030587] GO:0004721; GO:0004725; GO:0005737; GO:0006470; GO:0008330; GO:0017017; GO:0017018; GO:0030587; GO:0043409; GO:0072718 12829 FUN_001403 796 692 265 1155 1141 NA NA NA NA NA NA NA 12830 FUN_001402 3234 4324 2070 2175 2259 NA NA NA NA NA NA NA 12831 FUN_001401 289 217 217 310 156 ntLink_6:11949603-11951748 Q8C8M1 3.47e-22 SIN3-HDAC complex-associated factor (Protein FAM60A) (Tera protein) Mus musculus (Mouse) negative regulation of cell differentiation [GO:0045596]; negative regulation of cell migration [GO:0030336]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of stem cell population maintenance [GO:1902459] GO:0000122; GO:0005634; GO:0008284; GO:0016580; GO:0030336; GO:0030512; GO:0045596; GO:1902455; GO:1902459 12832 FUN_001400 32 5 55 43 95 NA NA NA NA NA NA NA 12833 FUN_001409 11 10 36 38 14 NA NA NA NA NA NA NA 12834 FUN_001408 33 33 42 39 32 NA NA NA NA NA NA NA 12835 FUN_016061 789 693 671 115 624 NA NA NA NA NA NA NA 12836 FUN_026162 2016 5186 1493 1677 1513 NA NA NA NA NA NA NA 12837 FUN_026161 957 835 500 1227 1053 ptg000020l:5397419-5399195 Q8N0W4 1.55e-84 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 12838 FUN_026160 6 7 57 3 12 ptg000020l:5393038-5393974 Q8N0W4 2.23e-24 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 12839 FUN_026167 1207 431 513 1107 1250 NA NA NA NA NA NA NA 12840 FUN_026166 6801 6669 3093 5440 4505 ptg000020l:5453518-5462857 P62198 3.31e-41 26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG) Rattus norvegicus (Rat) modulation of chemical synaptic transmission [GO:0050804]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of inclusion body assembly [GO:0090261]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000502; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005838; GO:0006357; GO:0008540; GO:0016234; GO:0016887; GO:0017025; GO:0022624; GO:0031410; GO:0031531; GO:0031595; GO:0031597; GO:0036402; GO:0043161; GO:0045892; GO:0050804; GO:0090261; GO:0098794; GO:0099576; GO:0140296; GO:0140297 12841 FUN_026166 6801 6669 3093 5440 4505 ptg000020l:5453518-5462857 P62198 6.41e-26 26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG) Rattus norvegicus (Rat) modulation of chemical synaptic transmission [GO:0050804]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of inclusion body assembly [GO:0090261]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000502; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005838; GO:0006357; GO:0008540; GO:0016234; GO:0016887; GO:0017025; GO:0022624; GO:0031410; GO:0031531; GO:0031595; GO:0031597; GO:0036402; GO:0043161; GO:0045892; GO:0050804; GO:0090261; GO:0098794; GO:0099576; GO:0140296; GO:0140297 12842 FUN_026165 4728 2750 1537 1999 2572 NA NA NA NA NA NA NA 12843 FUN_026164 266 142 53 50 290 NA NA NA NA NA NA NA 12844 FUN_016060 287 207 208 19 477 NA NA NA NA NA NA NA 12845 FUN_026169 12 15 0 0 12 NA NA NA NA NA NA NA 12846 FUN_026168 42 107 40 39 4 NA NA NA NA NA NA NA 12847 FUN_042837 5822 4348 3547 8497 6147 ptg000047l:734342-749928 F1R5H6 6.76e-25 Bromodomain-containing protein 4 Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of DNA-templated transcription [GO:0006355]; regulation of inflammatory response [GO:0050727]; thrombocyte differentiation [GO:0002574] GO:0000785; GO:0000793; GO:0002039; GO:0002574; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0032968; GO:0042393; GO:0043123; GO:0045944; GO:0050727; GO:0070577 12848 FUN_042837 5822 4348 3547 8497 6147 ptg000047l:734342-749928 F1R5H6 6.76e-25 Bromodomain-containing protein 4 Danio rerio (Zebrafish) (Brachydanio rerio) chromatin remodeling [GO:0006338]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; regulation of DNA-templated transcription [GO:0006355]; regulation of inflammatory response [GO:0050727]; thrombocyte differentiation [GO:0002574] GO:0000785; GO:0000793; GO:0002039; GO:0002574; GO:0003682; GO:0005634; GO:0006338; GO:0006355; GO:0032968; GO:0042393; GO:0043123; GO:0045944; GO:0050727; GO:0070577 12849 FUN_042835 1582 1222 1500 2880 1749 NA NA NA NA NA NA NA 12850 FUN_016063 652 465 660 517 496 NA NA NA NA NA NA NA 12851 FUN_042833 1822 1282 930 1546 687 NA NA NA NA NA NA NA 12852 FUN_042832 11 20 47 66 63 NA NA NA NA NA NA NA 12853 FUN_016751 36 45 0 58 6 ptg000011l:6963243-6969988 Q96AY4 2.68e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12854 FUN_016751 36 45 0 58 6 ptg000011l:6963243-6969988 Q96AY4 1.08e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12855 FUN_016751 36 45 0 58 6 ptg000011l:6963243-6969988 Q96AY4 1.59e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12856 FUN_016751 36 45 0 58 6 ptg000011l:6963243-6969988 Q96AY4 9.29e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12857 FUN_042830 721 652 314 789 688 NA NA NA NA NA NA NA 12858 FUN_016062 609 346 260 282 289 NA NA NA NA NA NA NA 12859 FUN_040063 909 788 592 463 539 NA NA NA NA NA NA NA 12860 FUN_004044 0 11 0 0 21 NA NA NA NA NA NA NA 12861 FUN_004045 196 221 175 275 126 NA NA NA NA NA NA NA 12862 FUN_004046 52 54 39 49 54 NA NA NA NA NA NA NA 12863 FUN_040061 16829 28636 15832 19570 12847 NA NA NA NA NA NA NA 12864 FUN_004040 2865 1661 1564 2792 2194 ntLink_8:18540497-18564651 Q5TAX3 1.77e-21 Terminal uridylyltransferase 4 (TUTase 4) (EC 2.7.7.52) (Zinc finger CCHC domain-containing protein 11) Homo sapiens (Human) miRNA catabolic process [GO:0010587]; miRNA metabolic process [GO:0010586]; negative regulation of transposition, RNA-mediated [GO:0010526]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oocyte maturation [GO:0001556]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; pre-miRNA processing [GO:0031054]; RNA 3' uridylation [GO:0071076]; RNA 3'-end processing [GO:0031123]; stem cell population maintenance [GO:0019827] GO:0000289; GO:0001556; GO:0003723; GO:0005615; GO:0005730; GO:0005737; GO:0005829; GO:0008270; GO:0010526; GO:0010586; GO:0010587; GO:0016779; GO:0019827; GO:0031054; GO:0031123; GO:0035198; GO:0036464; GO:0050265; GO:0070062; GO:0071076; GO:1990074 12865 FUN_004041 90 60 42 70 53 NA NA NA NA NA NA NA 12866 FUN_004042 5122 4889 2660 4862 3005 NA NA NA NA NA NA NA 12867 FUN_004043 29 0 0 14 7 NA NA NA NA NA NA NA 12868 FUN_003632 0 0 36 0 11 NA NA NA NA NA NA NA 12869 FUN_004048 10 50 9 0 37 NA NA NA NA NA NA NA 12870 FUN_004049 0 0 0 0 9 NA NA NA NA NA NA NA 12871 FUN_018053 4957 233 2961 49 2061 NA NA NA NA NA NA NA 12872 FUN_018050 23 62 55 64 0 NA NA NA NA NA NA NA 12873 FUN_018051 17 147 50 42 27 NA NA NA NA NA NA NA 12874 FUN_018054 30 288 295 349 302 NA NA NA NA NA NA NA 12875 FUN_018055 12010 2958 1494 1624 518 NA NA NA NA NA NA NA 12876 FUN_018058 17 44 20 22 1 NA NA NA NA NA NA NA 12877 FUN_040065 319 186 225 199 363 NA NA NA NA NA NA NA 12878 FUN_040068 2156 1853 1359 1412 1308 NA NA NA NA NA NA NA 12879 FUN_033842 133 85 78 121 71 NA NA NA NA NA NA NA 12880 FUN_033843 1527 1052 1079 1459 2174 ptg000024l:1801980-1824221 Q6P6Z0 2.64e-23 DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) Xenopus laevis (African clawed frog) DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0003677; GO:0005634; GO:0005737; GO:0006281; GO:0016567; GO:0031464; GO:0031465; GO:0042752; GO:0043161; GO:0048511; GO:0080008 12881 FUN_033843 1527 1052 1079 1459 2174 ptg000024l:1801980-1824221 Q6P6Z0 7.86e-23 DNA damage-binding protein 1 (Damage-specific DNA-binding protein 1) Xenopus laevis (African clawed frog) DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0003677; GO:0005634; GO:0005737; GO:0006281; GO:0016567; GO:0031464; GO:0031465; GO:0042752; GO:0043161; GO:0048511; GO:0080008 12882 FUN_033840 185 59 62 37 251 NA NA NA NA NA NA NA 12883 FUN_033841 67 36 69 64 92 NA NA NA NA NA NA NA 12884 FUN_033847 36 0 0 0 84 NA NA NA NA NA NA NA 12885 FUN_033844 2093 941 1173 1798 1258 ptg000024l:1825865-1832252 Q5FYB1 9.05e-21 Arylsulfatase I (ASI) (EC 3.1.6.-) Homo sapiens (Human) NA GO:0004065; GO:0005576; GO:0005788; GO:0046872 12886 FUN_033845 2950 690 1008 1852 1040 NA NA NA NA NA NA NA 12887 FUN_033849 10 0 41 0 151 NA NA NA NA NA NA NA 12888 FUN_031992 0 0 0 27 54 NA NA NA NA NA NA NA 12889 FUN_031993 25 0 0 23 37 NA NA NA NA NA NA NA 12890 FUN_031990 0 0 0 29 27 NA NA NA NA NA NA NA 12891 FUN_010842 254 372 221 404 635 ptg000007l:3499148-3500287 Q8NEA4 5.03e-45 F-box only protein 36 Homo sapiens (Human) NA NA 12892 FUN_031996 2 10 5 9 47 NA NA NA NA NA NA NA 12893 FUN_031997 0 23 0 0 0 NA NA NA NA NA NA NA 12894 FUN_031994 0 0 0 4 9 NA NA NA NA NA NA NA 12895 FUN_031995 0 0 0 0 17 NA NA NA NA NA NA NA 12896 FUN_043618 827 342 430 1004 393 ptg000047l:10855518-10856777 P34821 9.5e-37 Bone morphogenetic protein 8A (BMP-8A) (Osteogenic protein 2) (OP-2) Mus musculus (Mouse) BMP signaling pathway [GO:0030509]; cartilage development [GO:0051216]; germ cell development [GO:0007281]; osteoblast differentiation [GO:0001649]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395]; spermatogenesis [GO:0007283]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001649; GO:0005125; GO:0005615; GO:0007179; GO:0007281; GO:0007283; GO:0008083; GO:0010862; GO:0030509; GO:0051216; GO:0060395; GO:0070700 12897 FUN_031998 30 9 0 75 85 NA NA NA NA NA NA NA 12898 FUN_031999 0 0 0 22 19 NA NA NA NA NA NA NA 12899 FUN_010844 20 51 22 41 24 ptg000007l:3514091-3520686 Q96AY4 4.47e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12900 FUN_010844 20 51 22 41 24 ptg000007l:3514091-3520686 Q96AY4 6.55e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12901 FUN_010844 20 51 22 41 24 ptg000007l:3514091-3520686 Q96AY4 1.05e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 12902 FUN_034317 68 88 146 91 143 NA NA NA NA NA NA NA 12903 FUN_034316 916 623 409 508 413 NA NA NA NA NA NA NA 12904 FUN_034315 396 388 141 291 363 ptg000024l:7549437-7564267 Q91WD7 1.26e-38 Kinesin-like protein KIF18A Mus musculus (Mouse) cellular response to estradiol stimulus [GO:0071392]; male meiotic nuclear division [GO:0007140]; microtubule depolymerization [GO:0007019]; microtubule-based movement [GO:0007018]; mitotic metaphase plate congression [GO:0007080]; mitotic sister chromatid segregation [GO:0000070]; protein transport [GO:0015031]; regulation of microtubule cytoskeleton organization [GO:0070507]; seminiferous tubule development [GO:0072520] GO:0000070; GO:0000776; GO:0001726; GO:0003777; GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005815; GO:0005828; GO:0005871; GO:0005874; GO:0005901; GO:0007018; GO:0007019; GO:0007080; GO:0007140; GO:0008017; GO:0008574; GO:0015031; GO:0015630; GO:0016887; GO:0051010; GO:0061673; GO:0070463; GO:0070507; GO:0071392; GO:0072520; GO:1990023 12905 FUN_034314 14 0 0 31 0 ptg000024l:7529983-7532234 Q91YB0 2.27e-32 Circadian locomoter output cycles protein kaput (EC 2.3.1.48) Nannospalax galili (Northern Israeli blind subterranean mole rat) (Spalax galili) cellular response to DNA damage stimulus [GO:0006974]; circadian regulation of gene expression [GO:0032922]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein acetylation [GO:0006473]; regulation of circadian rhythm [GO:0042752]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283] GO:0000978; GO:0003677; GO:0003700; GO:0004402; GO:0005634; GO:0005667; GO:0005829; GO:0006355; GO:0006473; GO:0006974; GO:0007283; GO:0032922; GO:0033391; GO:0042634; GO:0042752; GO:0043161; GO:0045893; GO:0046983; GO:0050796; GO:0051092; GO:0051775; GO:0070888; GO:2000074 12906 FUN_034313 2218 1804 1531 2337 2148 NA NA NA NA NA NA NA 12907 FUN_034312 1979 1198 649 1280 590 NA NA NA NA NA NA NA 12908 FUN_034311 17 0 15 0 37 NA NA NA NA NA NA NA 12909 FUN_034310 59 0 57 0 0 NA NA NA NA NA NA NA 12910 FUN_034319 188 187 102 335 244 NA NA NA NA NA NA NA 12911 FUN_043614 2498 1477 1584 3272 3072 NA NA NA NA NA NA NA 12912 FUN_043615 200 162 137 323 310 NA NA NA NA NA NA NA 12913 FUN_030034 0 0 0 8 0 NA NA NA NA NA NA NA 12914 FUN_007029 175 67 93 289 193 ptg000001l:19546241-19546931 Q9GMB8 1.9e-21 Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) Bos taurus (Bovine) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0097056; GO:0098619; GO:1904046 12915 FUN_007028 195 74 104 333 251 ptg000001l:19541661-19542351 Q9GMB8 1.9e-21 Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) Bos taurus (Bovine) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0097056; GO:0098619; GO:1904046 12916 FUN_007027 309 99 174 488 365 ptg000001l:19537081-19537771 Q9GMB8 1.9e-21 Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) Bos taurus (Bovine) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0097056; GO:0098619; GO:1904046 12917 FUN_007026 5273 4385 2360 2549 5343 ptg000001l:19524021-19531086 Q6P799 1.07e-25 Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase) Rattus norvegicus (Rat) cytoplasmic translation [GO:0002181]; negative regulation of angiogenesis [GO:0016525]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular endothelial growth factor production [GO:1904046]; selenocysteine incorporation [GO:0001514]; selenocysteinyl-tRNA(Sec) biosynthetic process [GO:0097056]; seryl-tRNA aminoacylation [GO:0006434] GO:0000049; GO:0000122; GO:0000978; GO:0001514; GO:0002181; GO:0004828; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006434; GO:0016525; GO:0019899; GO:0042803; GO:0097056; GO:0098619; GO:1904046 12918 FUN_007025 4082 3681 1955 1147 3010 ptg000001l:19432370-19519571 P14381 4.45e-54 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 12919 FUN_007025 4082 3681 1955 1147 3010 ptg000001l:19432370-19519571 P14381 4.45e-54 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 12920 FUN_007024 89951 46673 44102 70639 25639 ptg000001l:19427968-19432123 P27080 5.66e-83 ADP,ATP carrier protein (ADP/ATP translocase) (Adenine nucleotide translocator) (ANT) Chlamydomonas reinhardtii (Chlamydomonas smithii) mitochondrial ADP transmembrane transport [GO:0140021]; mitochondrial ATP transmembrane transport [GO:1990544] GO:0005471; GO:0005743; GO:0140021; GO:1990544 12921 FUN_007023 1054 485 465 558 745 NA NA NA NA NA NA NA 12922 FUN_007022 18072 8750 9775 11463 6246 ptg000001l:19386902-19398415 Q8WP19 4.93e-57 Cryptochrome-1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein ubiquitination [GO:0031398]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to activity [GO:0014823]; response to glucagon [GO:0033762]; response to light stimulus [GO:0009416]; signal transduction in response to DNA damage [GO:0042770] GO:0000122; GO:0000166; GO:0005634; GO:0005737; GO:0006094; GO:0007623; GO:0009416; GO:0009881; GO:0014823; GO:0031397; GO:0031398; GO:0032922; GO:0033762; GO:0042593; GO:0042752; GO:0042754; GO:0042770; GO:0043153; GO:0045721; GO:0045744; GO:0045892; GO:2000001; GO:2000323 12923 FUN_007022 18072 8750 9775 11463 6246 ptg000001l:19386902-19398415 Q8WP19 8.51e-41 Cryptochrome-1 Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of protein ubiquitination [GO:0031398]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; response to activity [GO:0014823]; response to glucagon [GO:0033762]; response to light stimulus [GO:0009416]; signal transduction in response to DNA damage [GO:0042770] GO:0000122; GO:0000166; GO:0005634; GO:0005737; GO:0006094; GO:0007623; GO:0009416; GO:0009881; GO:0014823; GO:0031397; GO:0031398; GO:0032922; GO:0033762; GO:0042593; GO:0042752; GO:0042754; GO:0042770; GO:0043153; GO:0045721; GO:0045744; GO:0045892; GO:2000001; GO:2000323 12924 FUN_007021 3008 3365 2130 2218 3148 NA NA NA NA NA NA NA 12925 FUN_007020 26854 17053 14292 23332 17022 ptg000001l:19366430-19381367 Q32Q86 5.4e-55 Cryptochrome-1 Rattus norvegicus (Rat) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein ubiquitination [GO:0031398]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; regulation of gluconeogenesis [GO:0006111]; response to activity [GO:0014823]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]; selective autophagy [GO:0061912]; signal transduction in response to DNA damage [GO:0042770] GO:0000122; GO:0003677; GO:0003690; GO:0005634; GO:0005737; GO:0005739; GO:0006094; GO:0006111; GO:0007623; GO:0009416; GO:0009881; GO:0014823; GO:0016922; GO:0019900; GO:0019901; GO:0019902; GO:0019915; GO:0031397; GO:0031398; GO:0032868; GO:0032922; GO:0033762; GO:0042593; GO:0042752; GO:0042754; GO:0042770; GO:0042826; GO:0043153; GO:0045721; GO:0045722; GO:0045744; GO:0045892; GO:0061912; GO:0070888; GO:0071949; GO:0140297; GO:2000001; GO:2000323; GO:2000850 12926 FUN_007020 26854 17053 14292 23332 17022 ptg000001l:19366430-19381367 Q32Q86 2.84e-53 Cryptochrome-1 Rattus norvegicus (Rat) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein ubiquitination [GO:0031398]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; regulation of gluconeogenesis [GO:0006111]; response to activity [GO:0014823]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]; selective autophagy [GO:0061912]; signal transduction in response to DNA damage [GO:0042770] GO:0000122; GO:0003677; GO:0003690; GO:0005634; GO:0005737; GO:0005739; GO:0006094; GO:0006111; GO:0007623; GO:0009416; GO:0009881; GO:0014823; GO:0016922; GO:0019900; GO:0019901; GO:0019902; GO:0019915; GO:0031397; GO:0031398; GO:0032868; GO:0032922; GO:0033762; GO:0042593; GO:0042752; GO:0042754; GO:0042770; GO:0042826; GO:0043153; GO:0045721; GO:0045722; GO:0045744; GO:0045892; GO:0061912; GO:0070888; GO:0071949; GO:0140297; GO:2000001; GO:2000323; GO:2000850 12927 FUN_007020 26854 17053 14292 23332 17022 ptg000001l:19366430-19381367 Q32Q86 4.32e-48 Cryptochrome-1 Rattus norvegicus (Rat) circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; entrainment of circadian clock by photoperiod [GO:0043153]; gluconeogenesis [GO:0006094]; glucose homeostasis [GO:0042593]; lipid storage [GO:0019915]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of glucocorticoid receptor signaling pathway [GO:2000323]; negative regulation of glucocorticoid secretion [GO:2000850]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gluconeogenesis [GO:0045722]; positive regulation of protein ubiquitination [GO:0031398]; regulation of circadian rhythm [GO:0042752]; regulation of DNA damage checkpoint [GO:2000001]; regulation of gluconeogenesis [GO:0006111]; response to activity [GO:0014823]; response to glucagon [GO:0033762]; response to insulin [GO:0032868]; response to light stimulus [GO:0009416]; selective autophagy [GO:0061912]; signal transduction in response to DNA damage [GO:0042770] GO:0000122; GO:0003677; GO:0003690; GO:0005634; GO:0005737; GO:0005739; GO:0006094; GO:0006111; GO:0007623; GO:0009416; GO:0009881; GO:0014823; GO:0016922; GO:0019900; GO:0019901; GO:0019902; GO:0019915; GO:0031397; GO:0031398; GO:0032868; GO:0032922; GO:0033762; GO:0042593; GO:0042752; GO:0042754; GO:0042770; GO:0042826; GO:0043153; GO:0045721; GO:0045722; GO:0045744; GO:0045892; GO:0061912; GO:0070888; GO:0071949; GO:0140297; GO:2000001; GO:2000323; GO:2000850 12928 FUN_005873 5135 2607 2215 4670 3071 NA NA NA NA NA NA NA 12929 FUN_005876 14 0 0 0 8 NA NA NA NA NA NA NA 12930 FUN_005877 1120 34 787 34 22 NA NA NA NA NA NA NA 12931 FUN_005874 0 46 20 36 42 NA NA NA NA NA NA NA 12932 FUN_005875 7 0 13 14 57 NA NA NA NA NA NA NA 12933 FUN_005878 1536 2245 824 870 666 ptg000001l:5173365-5177393 Q9WVD5 4.46e-39 Mitochondrial ornithine transporter 1 (Solute carrier family 25 member 15) Mus musculus (Mouse) L-arginine transmembrane transport [GO:1903826]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575] GO:0000064; GO:0005739; GO:0005743; GO:0015189; GO:0015297; GO:0022857; GO:0061459; GO:1903401; GO:1903826; GO:1990575 12934 FUN_005879 229 156 98 200 83 ptg000001l:5179785-5181233 Q58DT4 6.59e-68 Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561] GO:0004735; GO:0005739; GO:0006561; GO:0034599; GO:0055129 12935 FUN_019015 398 345 306 381 523 NA NA NA NA NA NA NA 12936 FUN_006992 173 149 202 449 178 NA NA NA NA NA NA NA 12937 FUN_019016 20 25 12 86 71 NA NA NA NA NA NA NA 12938 FUN_006994 7 2104 663 3 738 NA NA NA NA NA NA NA 12939 FUN_019010 0 0 0 16 19 NA NA NA NA NA NA NA 12940 FUN_006996 1569 1178 996 1559 1368 NA NA NA NA NA NA NA 12941 FUN_006997 297 137 157 308 191 NA NA NA NA NA NA NA 12942 FUN_006998 30 0 0 18 31 ptg000001l:19178150-19180476 P49287 3.33e-23 Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Rattus norvegicus (Rat) camera-type eye development [GO:0043010]; G protein-coupled receptor signaling pathway [GO:0007186]; glucose homeostasis [GO:0042593]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transmission of nerve impulse [GO:0051970]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of insulin secretion [GO:0050796]; regulation of neuronal action potential [GO:0098908] GO:0004930; GO:0005886; GO:0007186; GO:0008502; GO:0010754; GO:0042593; GO:0042753; GO:0043010; GO:0043524; GO:0045906; GO:0046010; GO:0046676; GO:0050796; GO:0051481; GO:0051970; GO:0051971; GO:0098908; GO:1902260 12943 FUN_006999 1282 629 613 1170 933 NA NA NA NA NA NA NA 12944 FUN_019019 87 27 35 134 44 NA NA NA NA NA NA NA 12945 FUN_019018 14 0 0 7 0 NA NA NA NA NA NA NA 12946 FUN_034865 19077 20023 13270 16433 8678 ptg000025l:1016976-1017483 Q641G7 1.29e-107 Actin-related protein 2/3 complex subunit 4 Xenopus laevis (African clawed frog) actin filament polymerization [GO:0030041]; Arp2/3 complex-mediated actin nucleation [GO:0034314] GO:0003779; GO:0005634; GO:0005737; GO:0005885; GO:0030041; GO:0034314; GO:0035861; GO:0042995 12947 FUN_034864 6377 5276 4014 7585 5769 ptg000025l:978080-1016621 Q6ZQ08 4.26e-40 CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) Mus musculus (Mouse) miRNA-mediated gene silencing [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000288; GO:0000932; GO:0001829; GO:0004535; GO:0005634; GO:0005829; GO:0010606; GO:0017148; GO:0019904; GO:0030014; GO:0030015; GO:0030331; GO:0033147; GO:0035195; GO:0042974; GO:0048387; GO:0060090; GO:0060213; GO:0061014; GO:0070016; GO:1900153; GO:2000036 12948 FUN_034864 6377 5276 4014 7585 5769 ptg000025l:978080-1016621 Q6ZQ08 4.26e-40 CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) Mus musculus (Mouse) miRNA-mediated gene silencing [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000288; GO:0000932; GO:0001829; GO:0004535; GO:0005634; GO:0005829; GO:0010606; GO:0017148; GO:0019904; GO:0030014; GO:0030015; GO:0030331; GO:0033147; GO:0035195; GO:0042974; GO:0048387; GO:0060090; GO:0060213; GO:0061014; GO:0070016; GO:1900153; GO:2000036 12949 FUN_034864 6377 5276 4014 7585 5769 ptg000025l:978080-1016621 Q6ZQ08 2.01e-26 CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) Mus musculus (Mouse) miRNA-mediated gene silencing [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000288; GO:0000932; GO:0001829; GO:0004535; GO:0005634; GO:0005829; GO:0010606; GO:0017148; GO:0019904; GO:0030014; GO:0030015; GO:0030331; GO:0033147; GO:0035195; GO:0042974; GO:0048387; GO:0060090; GO:0060213; GO:0061014; GO:0070016; GO:1900153; GO:2000036 12950 FUN_034864 6377 5276 4014 7585 5769 ptg000025l:978080-1016621 Q6ZQ08 1.26e-21 CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) Mus musculus (Mouse) miRNA-mediated gene silencing [GO:0035195]; negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of translation [GO:0017148]; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:0000288]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of stem cell population maintenance [GO:2000036]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000288; GO:0000932; GO:0001829; GO:0004535; GO:0005634; GO:0005829; GO:0010606; GO:0017148; GO:0019904; GO:0030014; GO:0030015; GO:0030331; GO:0033147; GO:0035195; GO:0042974; GO:0048387; GO:0060090; GO:0060213; GO:0061014; GO:0070016; GO:1900153; GO:2000036 12951 FUN_034867 5251 2733 1864 4664 2914 ptg000025l:1021583-1030474 Q28193 1.81e-47 Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Trans Golgi network protease furin) Bos taurus (Bovine) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0008201; GO:0010008; GO:0046872; GO:1901394; GO:1904399 12952 FUN_034867 5251 2733 1864 4664 2914 ptg000025l:1021583-1030474 Q28193 8.87e-32 Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Trans Golgi network protease furin) Bos taurus (Bovine) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0008201; GO:0010008; GO:0046872; GO:1901394; GO:1904399 12953 FUN_034867 5251 2733 1864 4664 2914 ptg000025l:1021583-1030474 Q28193 6.53e-26 Furin (EC 3.4.21.75) (Dibasic-processing enzyme) (Paired basic amino acid residue-cleaving enzyme) (PACE) (Trans Golgi network protease furin) Bos taurus (Bovine) positive regulation of transforming growth factor beta1 activation [GO:1901394]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005794; GO:0005886; GO:0006508; GO:0008201; GO:0010008; GO:0046872; GO:1901394; GO:1904399 12954 FUN_034866 1236 329 287 1284 684 NA NA NA NA NA NA NA 12955 FUN_034861 12 0 0 0 13 NA NA NA NA NA NA NA 12956 FUN_034860 105 33 50 85 138 NA NA NA NA NA NA NA 12957 FUN_034863 25779 31654 13208 16383 15199 ptg000025l:972685-973114 Q4AEI3 4.66e-56 Glutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) Pongo pygmaeus (Bornean orangutan) arachidonic acid metabolic process [GO:0019369]; lipoxygenase pathway [GO:0019372]; response to oxidative stress [GO:0006979] GO:0004602; GO:0005737; GO:0006979; GO:0019369; GO:0019372; GO:0047066 12958 FUN_034862 2449 1496 1489 2484 3012 NA NA NA NA NA NA NA 12959 FUN_034869 812 236 239 298 446 ptg000025l:1039410-1040775 D3ZR10 5.33e-27 Doublecortin domain-containing protein 2 Rattus norvegicus (Rat) cilium assembly [GO:0060271]; dendrite morphogenesis [GO:0048813]; intracellular signal transduction [GO:0035556]; neuron migration [GO:0001764]; neuronal action potential [GO:0019228]; positive regulation of smoothened signaling pathway [GO:0045880]; regulation of cilium assembly [GO:1902017]; regulation of Wnt signaling pathway [GO:0030111]; sensory perception of sound [GO:0007605]; synaptic transmission, glutamatergic [GO:0035249]; visual learning [GO:0008542] GO:0001764; GO:0005737; GO:0005815; GO:0005829; GO:0005856; GO:0005874; GO:0005929; GO:0005930; GO:0007605; GO:0008542; GO:0019228; GO:0019894; GO:0030111; GO:0034451; GO:0035249; GO:0035556; GO:0045202; GO:0045880; GO:0048813; GO:0060091; GO:0060271; GO:0072686; GO:1902017 12960 FUN_034868 0 8 0 51 22 NA NA NA NA NA NA NA 12961 FUN_016140 6203 3393 3216 6407 5330 NA NA NA NA NA NA NA 12962 FUN_030349 6 0 7 0 27 ptg000023l:10673356-10674119 P84239 1.64e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 12963 FUN_035199 2361 4521 1443 1687 2009 NA NA NA NA NA NA NA 12964 FUN_035196 22 0 26 27 35 NA NA NA NA NA NA NA 12965 FUN_035197 0 0 0 9 15 NA NA NA NA NA NA NA 12966 FUN_035194 2150 2662 2105 2087 1279 NA NA NA NA NA NA NA 12967 FUN_030343 5 1 6 0 23 ptg000023l:10649046-10649809 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 12968 FUN_035192 15 31 18 76 64 NA NA NA NA NA NA NA 12969 FUN_013116 129 116 94 73 77 ptg000008l:19719664-19756746 P0CT39 1.43e-65 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 12970 FUN_013116 129 116 94 73 77 ptg000008l:19719664-19756746 P0CT39 1.43e-65 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 12971 FUN_013116 129 116 94 73 77 ptg000008l:19719664-19756746 P0CT39 1.43e-65 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 12972 FUN_004259 0 0 0 17 57 NA NA NA NA NA NA NA 12973 FUN_033964 6 0 8 45 2 ptg000024l:3187456-3194146 Q6DIL6 6.71e-29 Protein FAM124A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA NA 12974 FUN_006378 61 8 18 26 27 NA NA NA NA NA NA NA 12975 FUN_006379 4 235 64 77 146 NA NA NA NA NA NA NA 12976 FUN_042136 2241 1349 686 1972 2543 NA NA NA NA NA NA NA 12977 FUN_042135 5 0 0 10 4 NA NA NA NA NA NA NA 12978 FUN_042132 177586 103367 38424 78459 31076 NA NA NA NA NA NA NA 12979 FUN_042133 0 0 48 0 109 NA NA NA NA NA NA NA 12980 FUN_042130 89 40 20 57 13 ptg000036l:975693-986259 E9Q236 6.02e-64 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 12981 FUN_042130 89 40 20 57 13 ptg000036l:975693-986259 E9Q236 1.05e-25 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 12982 FUN_042130 89 40 20 57 13 ptg000036l:975693-986259 E9Q236 1.14e-24 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 12983 FUN_042131 11 0 0 0 0 NA NA NA NA NA NA NA 12984 FUN_033969 999 1086 793 862 558 NA NA NA NA NA NA NA 12985 FUN_033968 3473 2206 1430 2373 1342 NA NA NA NA NA NA NA 12986 FUN_010694 146 137 17 43 173 ptg000007l:1736778-1741481 E7FAM5 2.22e-76 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 12987 FUN_010694 146 137 17 43 173 ptg000007l:1736778-1741481 E7FAM5 1.78e-30 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 12988 FUN_010696 1513 1039 763 1410 791 ptg000007l:1748209-1774812 F4JTS8 1.11e-26 Protein NO VEIN (Protein EMBRYO DEFECTIVE 2597) Arabidopsis thaliana (Mouse-ear cress) auxin polar transport [GO:0009926]; cell fate specification [GO:0001708]; embryo development ending in seed dormancy [GO:0009793]; leaf vascular tissue pattern formation [GO:0010305]; root development [GO:0048364]; stem cell population maintenance [GO:0019827] GO:0001708; GO:0005634; GO:0009793; GO:0009926; GO:0010305; GO:0019827; GO:0048364 12989 FUN_035738 11050 8821 3350 8161 3352 NA NA NA NA NA NA NA 12990 FUN_035739 29 0 7 0 7 NA NA NA NA NA NA NA 12991 FUN_035732 124 124 167 163 141 ptg000025l:11065761-11068422 Q5ZLC8 1.08e-27 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 12992 FUN_028301 3436 1842 2293 4012 3688 NA NA NA NA NA NA NA 12993 FUN_035730 3331 1969 1781 2749 1492 ptg000025l:11059677-11062901 Q26636 3.7e-39 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 12994 FUN_035736 3892 1868 1870 4184 3987 ptg000025l:11115026-11124811 Q8JFV8 8.28e-25 Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of mitochondrial fusion [GO:0010637] GO:0005741; GO:0008270; GO:0010637; GO:0016491 12995 FUN_035737 5492 3349 3048 4877 4858 ptg000025l:11132074-11162519 A2AJK6 4.7e-116 Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7) Mus musculus (Mouse) adult heart development [GO:0007512]; adult walking behavior [GO:0007628]; aorta development [GO:0035904]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; atrioventricular canal development [GO:0036302]; blood circulation [GO:0008015]; blood vessel development [GO:0001568]; blood vessel remodeling [GO:0001974]; camera-type eye development [GO:0043010]; cardiac septum morphogenesis [GO:0060411]; central nervous system development [GO:0007417]; chordate embryonic development [GO:0043009]; chromatin remodeling [GO:0006338]; cognition [GO:0050890]; cranial nerve development [GO:0021545]; ear morphogenesis [GO:0042471]; embryonic hindlimb morphogenesis [GO:0035116]; epithelium development [GO:0060429]; face development [GO:0060324]; female genitalia development [GO:0030540]; genitalia development [GO:0048806]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; innervation [GO:0060384]; limb development [GO:0060173]; locomotory behavior [GO:0007626]; nose development [GO:0043584]; olfactory behavior [GO:0042048]; olfactory bulb development [GO:0021772]; olfactory nerve development [GO:0021553]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of growth hormone secretion [GO:0060123]; regulation of neurogenesis [GO:0050767]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880]; response to bacterium [GO:0009617]; retina development in camera-type eye [GO:0060041]; right ventricular compact myocardium morphogenesis [GO:0003226]; roof of mouth development [GO:0060021]; rRNA processing [GO:0006364]; secondary palate development [GO:0062009]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; T cell differentiation [GO:0030217]; tissue remodeling [GO:0048771]; transcription by RNA polymerase II [GO:0006366]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0000785; GO:0000978; GO:0001501; GO:0001568; GO:0001701; GO:0001974; GO:0003007; GO:0003222; GO:0003226; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006338; GO:0006364; GO:0006366; GO:0007417; GO:0007512; GO:0007605; GO:0007626; GO:0007628; GO:0008015; GO:0009617; GO:0010468; GO:0010880; GO:0016887; GO:0021545; GO:0021553; GO:0021772; GO:0030217; GO:0030540; GO:0035116; GO:0035904; GO:0035909; GO:0036302; GO:0040018; GO:0042048; GO:0042393; GO:0042471; GO:0042472; GO:0043009; GO:0043010; GO:0043584; GO:0045944; GO:0048752; GO:0048771; GO:0048806; GO:0048844; GO:0050767; GO:0050890; GO:0060021; GO:0060041; GO:0060123; GO:0060173; GO:0060324; GO:0060384; GO:0060411; GO:0060429; GO:0062009; GO:0140658; GO:1990841 12996 FUN_035734 3101 3107 3516 4106 3433 NA NA NA NA NA NA NA 12997 FUN_035735 2133 1481 1197 1771 1246 NA NA NA NA NA NA NA 12998 FUN_042680 0 0 2 7 6 NA NA NA NA NA NA NA 12999 FUN_042681 2 7 53 17 258 NA NA NA NA NA NA NA 13000 FUN_003829 24 1 3 25 20 NA NA NA NA NA NA NA 13001 FUN_003828 11 11 3 4 6 NA NA NA NA NA NA NA 13002 FUN_013115 22 11 26 21 12 NA NA NA NA NA NA NA 13003 FUN_042685 4 5 54 42 148 NA NA NA NA NA NA NA 13004 FUN_042687 7 7 60 18 374 NA NA NA NA NA NA NA 13005 FUN_042688 3 2 6 20 30 NA NA NA NA NA NA NA 13006 FUN_042689 0 4 1 6 5 NA NA NA NA NA NA NA 13007 FUN_003821 8 19 6 40 0 NA NA NA NA NA NA NA 13008 FUN_003820 0 0 0 20 0 NA NA NA NA NA NA NA 13009 FUN_003827 0 0 0 40 0 NA NA NA NA NA NA NA 13010 FUN_003824 0 8 8 0 34 NA NA NA NA NA NA NA 13011 FUN_004835 3056 2590 1436 2722 1464 NA NA NA NA NA NA NA 13012 FUN_004834 431 200 146 354 332 NA NA NA NA NA NA NA 13013 FUN_004837 547 427 187 508 553 NA NA NA NA NA NA NA 13014 FUN_004836 2189 1605 1581 2150 2113 NA NA NA NA NA NA NA 13015 FUN_004831 233 1879 1800 3750 973 NA NA NA NA NA NA NA 13016 FUN_004830 8 0 52 5 30 NA NA NA NA NA NA NA 13017 FUN_036425 0 0 20 0 11 NA NA NA NA NA NA NA 13018 FUN_031432 264 277 23 0 0 NA NA NA NA NA NA NA 13019 FUN_036423 0 0 0 0 8 NA NA NA NA NA NA NA 13020 FUN_031437 105 10 47 5 129 NA NA NA NA NA NA NA 13021 FUN_037778 2427 987 917 1605 1016 NA NA NA NA NA NA NA 13022 FUN_037779 14777 7078 3796 11183 5727 NA NA NA NA NA NA NA 13023 FUN_037774 4186 2984 1817 3509 1033 NA NA NA NA NA NA NA 13024 FUN_010698 5195 5331 2844 3442 2680 NA NA NA NA NA NA NA 13025 FUN_037776 601 149 295 336 76 NA NA NA NA NA NA NA 13026 FUN_037777 5999 3702 4295 6397 3866 ptg000026l:13449397-13500355 Q24JV9 4.43e-29 Galectin-3-binding protein A (Lectin galactoside-binding soluble 3-binding protein A) Danio rerio (Zebrafish) (Brachydanio rerio) cell adhesion [GO:0007155] GO:0005044; GO:0005576; GO:0007155; GO:0016020 13027 FUN_037777 5999 3702 4295 6397 3866 ptg000026l:13449397-13500355 Q24JV9 8.09e-22 Galectin-3-binding protein A (Lectin galactoside-binding soluble 3-binding protein A) Danio rerio (Zebrafish) (Brachydanio rerio) cell adhesion [GO:0007155] GO:0005044; GO:0005576; GO:0007155; GO:0016020 13028 FUN_037770 57258 74792 52592 49451 43560 NA NA NA NA NA NA NA 13029 FUN_037771 7 0 9 0 4 NA NA NA NA NA NA NA 13030 FUN_037772 4445 3928 3031 3422 5921 NA NA NA NA NA NA NA 13031 FUN_037773 105 82 66 272 22 NA NA NA NA NA NA NA 13032 FUN_016149 63 83 27 177 24 NA NA NA NA NA NA NA 13033 FUN_007562 256 237 105 236 52 NA NA NA NA NA NA NA 13034 FUN_007563 0 35 0 0 12 NA NA NA NA NA NA NA 13035 FUN_021799 0 0 0 12 0 NA NA NA NA NA NA NA 13036 FUN_021798 0 0 43 0 114 NA NA NA NA NA NA NA 13037 FUN_005058 158 68 66 290 164 NA NA NA NA NA NA NA 13038 FUN_000024 0 0 0 1 17 NA NA NA NA NA NA NA 13039 FUN_000025 0 0 0 0 6 NA NA NA NA NA NA NA 13040 FUN_005054 604 591 350 435 414 NA NA NA NA NA NA NA 13041 FUN_005055 95 84 0 28 25 NA NA NA NA NA NA NA 13042 FUN_000028 0 0 0 0 6 NA NA NA NA NA NA NA 13043 FUN_005057 2434 2007 1922 3740 2289 ntLink_8:30503288-30525216 P48765 1.27e-43 Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of calcium ion transport [GO:0051924]; regulation of sodium ion transport [GO:0002028]; regulation of the force of heart contraction [GO:0002026]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0002026; GO:0002028; GO:0005432; GO:0005509; GO:0005516; GO:0005886; GO:0005901; GO:0006814; GO:0006816; GO:0006874; GO:0007154; GO:0007204; GO:0035725; GO:0042383; GO:0051924; GO:0070588 13044 FUN_005050 1453 1268 861 1758 1343 NA NA NA NA NA NA NA 13045 FUN_005051 188 139 26 135 183 ntLink_8:30443315-30443747 A6NNL5 4.96e-57 Uncharacterized protein C15orf61 Homo sapiens (Human) NA GO:0005576 13046 FUN_005052 256 88 170 246 309 NA NA NA NA NA NA NA 13047 FUN_005053 5051 8540 4389 7119 2868 ntLink_8:30457027-30458404 Q8BN59 2.5e-38 La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6) Mus musculus (Mouse) positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of mRNA binding [GO:1902416]; positive regulation of translation [GO:0045727]; RNA processing [GO:0006396] GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0005844; GO:0006396; GO:0017022; GO:0032967; GO:0035613; GO:0045727; GO:0048027; GO:1902416; GO:1990825; GO:1990904 13048 FUN_002883 7 0 0 0 13 NA NA NA NA NA NA NA 13049 FUN_002880 0 0 0 0 8 NA NA NA NA NA NA NA 13050 FUN_002886 0 0 0 0 10 NA NA NA NA NA NA NA 13051 FUN_002887 136 53 86 317 467 NA NA NA NA NA NA NA 13052 FUN_002885 8 2 0 4 2 NA NA NA NA NA NA NA 13053 FUN_002888 3 0 0 3 54 NA NA NA NA NA NA NA 13054 FUN_002889 48 0 15 0 80 NA NA NA NA NA NA NA 13055 FUN_032858 8 0 11 20 26 NA NA NA NA NA NA NA 13056 FUN_032859 14 0 0 0 0 NA NA NA NA NA NA NA 13057 FUN_032852 26 9 49 23 20 NA NA NA NA NA NA NA 13058 FUN_032853 10 2 4 6 3 NA NA NA NA NA NA NA 13059 FUN_032856 0 7 0 0 0 NA NA NA NA NA NA NA 13060 FUN_032857 0 15 2 0 4 NA NA NA NA NA NA NA 13061 FUN_032854 4 2 7 0 11 NA NA NA NA NA NA NA 13062 FUN_032855 0 0 0 10 0 NA NA NA NA NA NA NA 13063 FUN_041560 954 801 554 660 345 NA NA NA NA NA NA NA 13064 FUN_013881 24 11 0 0 53 NA NA NA NA NA NA NA 13065 FUN_041563 0 0 0 11 0 NA NA NA NA NA NA NA 13066 FUN_041564 0 0 13 0 0 NA NA NA NA NA NA NA 13067 FUN_013885 4 39 31 0 12 NA NA NA NA NA NA NA 13068 FUN_041567 564 279 178 428 477 ptg000035l:5356211-5367276 Q924A2 1.63e-24 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 13069 FUN_041567 564 279 178 428 477 ptg000035l:5356211-5367276 Q924A2 1.51e-21 Protein capicua homolog Mus musculus (Mouse) brain development [GO:0007420]; learning [GO:0007612]; lung alveolus development [GO:0048286]; memory [GO:0007613]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357]; social behavior [GO:0035176]; transcription by RNA polymerase II [GO:0006366] GO:0000122; GO:0000977; GO:0000981; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0006366; GO:0007420; GO:0007612; GO:0007613; GO:0032991; GO:0035176; GO:0043231; GO:0045892; GO:0048286 13070 FUN_041568 19 0 0 0 0 NA NA NA NA NA NA NA 13071 FUN_041569 2538 1665 1641 2678 1532 NA NA NA NA NA NA NA 13072 FUN_021796 0 0 0 0 17 NA NA NA NA NA NA NA 13073 FUN_013399 1458 1893 1344 1672 1595 NA NA NA NA NA NA NA 13074 FUN_004967 0 0 19 58 0 NA NA NA NA NA NA NA 13075 FUN_033108 0 0 16 0 13 NA NA NA NA NA NA NA 13076 FUN_033107 0 1 0 13 7 NA NA NA NA NA NA NA 13077 FUN_033106 0 8 11 28 35 NA NA NA NA NA NA NA 13078 FUN_033105 0 0 0 35 20 NA NA NA NA NA NA NA 13079 FUN_033104 18 0 0 8 9 NA NA NA NA NA NA NA 13080 FUN_033103 6 0 4 16 61 NA NA NA NA NA NA NA 13081 FUN_033102 1 0 0 5 8 NA NA NA NA NA NA NA 13082 FUN_033100 0 0 7 0 4 NA NA NA NA NA NA NA 13083 FUN_038646 444 302 185 305 475 NA NA NA NA NA NA NA 13084 FUN_013395 46 42 13 69 44 NA NA NA NA NA NA NA 13085 FUN_013396 2177 3610 1912 1973 1902 NA NA NA NA NA NA NA 13086 FUN_038640 0 8 0 0 34 NA NA NA NA NA NA NA 13087 FUN_013397 637 272 417 619 418 NA NA NA NA NA NA NA 13088 FUN_004961 0 8 0 1 0 NA NA NA NA NA NA NA 13089 FUN_013390 1980 1131 676 1665 1508 NA NA NA NA NA NA NA 13090 FUN_023640 269 350 620 263 709 NA NA NA NA NA NA NA 13091 FUN_042919 315 228 537 1694 609 ptg000047l:1772928-1778879 Q12933 2.78e-66 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 13092 FUN_042910 8492 3730 2941 7123 4446 NA NA NA NA NA NA NA 13093 FUN_042912 2116 2206 918 1058 925 NA NA NA NA NA NA NA 13094 FUN_042913 1021 1142 632 657 503 NA NA NA NA NA NA NA 13095 FUN_016634 5 529 1 369 460 NA NA NA NA NA NA NA 13096 FUN_042915 16 0 0 0 32 NA NA NA NA NA NA NA 13097 FUN_016636 1863 843 764 1709 1016 ptg000011l:5653147-5665199 O46680 9.66e-45 TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) Bos taurus (Bovine) activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epicardium morphogenesis [GO:1905223]; filopodium assembly [GO:0046847]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001822; GO:0001824; GO:0001935; GO:0001937; GO:0001938; GO:0002088; GO:0003222; GO:0003223; GO:0004674; GO:0005025; GO:0005114; GO:0005524; GO:0005634; GO:0005768; GO:0005886; GO:0005923; GO:0006468; GO:0006915; GO:0007179; GO:0007399; GO:0007507; GO:0008354; GO:0008584; GO:0009791; GO:0009952; GO:0009986; GO:0010468; GO:0010628; GO:0010717; GO:0010862; GO:0016020; GO:0016361; GO:0018105; GO:0018107; GO:0030199; GO:0030307; GO:0030335; GO:0031396; GO:0032331; GO:0032924; GO:0035556; GO:0042118; GO:0043235; GO:0043393; GO:0043410; GO:0043542; GO:0045121; GO:0045893; GO:0046332; GO:0046847; GO:0046872; GO:0048179; GO:0048185; GO:0048538; GO:0048663; GO:0048701; GO:0048762; GO:0050431; GO:0051491; GO:0051496; GO:0051897; GO:0060017; GO:0060021; GO:0060037; GO:0060043; GO:0060317; GO:0060389; GO:0060391; GO:0060412; GO:0060978; GO:0060982; GO:0070021; GO:0070411; GO:0070723; GO:0071363; GO:0071560; GO:1905007; GO:1905075; GO:1905223; GO:2001235; GO:2001237 13098 FUN_016636 1863 843 764 1709 1016 ptg000011l:5653147-5665199 O46680 1e-32 TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) Bos taurus (Bovine) activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epicardium morphogenesis [GO:1905223]; filopodium assembly [GO:0046847]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001822; GO:0001824; GO:0001935; GO:0001937; GO:0001938; GO:0002088; GO:0003222; GO:0003223; GO:0004674; GO:0005025; GO:0005114; GO:0005524; GO:0005634; GO:0005768; GO:0005886; GO:0005923; GO:0006468; GO:0006915; GO:0007179; GO:0007399; GO:0007507; GO:0008354; GO:0008584; GO:0009791; GO:0009952; GO:0009986; GO:0010468; GO:0010628; GO:0010717; GO:0010862; GO:0016020; GO:0016361; GO:0018105; GO:0018107; GO:0030199; GO:0030307; GO:0030335; GO:0031396; GO:0032331; GO:0032924; GO:0035556; GO:0042118; GO:0043235; GO:0043393; GO:0043410; GO:0043542; GO:0045121; GO:0045893; GO:0046332; GO:0046847; GO:0046872; GO:0048179; GO:0048185; GO:0048538; GO:0048663; GO:0048701; GO:0048762; GO:0050431; GO:0051491; GO:0051496; GO:0051897; GO:0060017; GO:0060021; GO:0060037; GO:0060043; GO:0060317; GO:0060389; GO:0060391; GO:0060412; GO:0060978; GO:0060982; GO:0070021; GO:0070411; GO:0070723; GO:0071363; GO:0071560; GO:1905007; GO:1905075; GO:1905223; GO:2001235; GO:2001237 13099 FUN_016636 1863 843 764 1709 1016 ptg000011l:5653147-5665199 O46680 1.16e-27 TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) Bos taurus (Bovine) activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epicardium morphogenesis [GO:1905223]; filopodium assembly [GO:0046847]; germ cell migration [GO:0008354]; heart development [GO:0007507]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222] GO:0001822; GO:0001824; GO:0001935; GO:0001937; GO:0001938; GO:0002088; GO:0003222; GO:0003223; GO:0004674; GO:0005025; GO:0005114; GO:0005524; GO:0005634; GO:0005768; GO:0005886; GO:0005923; GO:0006468; GO:0006915; GO:0007179; GO:0007399; GO:0007507; GO:0008354; GO:0008584; GO:0009791; GO:0009952; GO:0009986; GO:0010468; GO:0010628; GO:0010717; GO:0010862; GO:0016020; GO:0016361; GO:0018105; GO:0018107; GO:0030199; GO:0030307; GO:0030335; GO:0031396; GO:0032331; GO:0032924; GO:0035556; GO:0042118; GO:0043235; GO:0043393; GO:0043410; GO:0043542; GO:0045121; GO:0045893; GO:0046332; GO:0046847; GO:0046872; GO:0048179; GO:0048185; GO:0048538; GO:0048663; GO:0048701; GO:0048762; GO:0050431; GO:0051491; GO:0051496; GO:0051897; GO:0060017; GO:0060021; GO:0060037; GO:0060043; GO:0060317; GO:0060389; GO:0060391; GO:0060412; GO:0060978; GO:0060982; GO:0070021; GO:0070411; GO:0070723; GO:0071363; GO:0071560; GO:1905007; GO:1905075; GO:1905223; GO:2001235; GO:2001237 13100 FUN_016637 10 0 0 0 0 NA NA NA NA NA NA NA 13101 FUN_003593 0 0 27 0 0 NA NA NA NA NA NA NA 13102 FUN_003592 0 0 0 0 7 NA NA NA NA NA NA NA 13103 FUN_003591 83 0 40 62 47 NA NA NA NA NA NA NA 13104 FUN_003596 0 0 9 0 0 NA NA NA NA NA NA NA 13105 FUN_003594 0 0 28 0 1 NA NA NA NA NA NA NA 13106 FUN_003598 0 0 21 0 0 NA NA NA NA NA NA NA 13107 FUN_040215 625 361 391 627 591 NA NA NA NA NA NA NA 13108 FUN_040217 1321 1030 932 1616 1709 NA NA NA NA NA NA NA 13109 FUN_040216 276 248 122 96 213 NA NA NA NA NA NA NA 13110 FUN_040219 0 0 0 12 0 NA NA NA NA NA NA NA 13111 FUN_040218 89 0 41 68 259 NA NA NA NA NA NA NA 13112 FUN_034458 349 362 177 839 670 ptg000024l:9021434-9037181 Q9DEI1 2.91e-48 DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) Xenopus laevis (African clawed frog) double-strand break repair via nonhomologous end joining [GO:0006303]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; phosphorylation [GO:0016310]; ribosome biogenesis [GO:0042254] GO:0004674; GO:0004677; GO:0005524; GO:0005730; GO:0006303; GO:0016310; GO:0031571; GO:0042254; GO:0070419; GO:0106310 13113 FUN_034458 349 362 177 839 670 ptg000024l:9021434-9037181 Q9DEI1 2.91e-48 DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) Xenopus laevis (African clawed frog) double-strand break repair via nonhomologous end joining [GO:0006303]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; phosphorylation [GO:0016310]; ribosome biogenesis [GO:0042254] GO:0004674; GO:0004677; GO:0005524; GO:0005730; GO:0006303; GO:0016310; GO:0031571; GO:0042254; GO:0070419; GO:0106310 13114 FUN_034459 48 0 50 86 36 NA NA NA NA NA NA NA 13115 FUN_034455 118 15 46 35 93 NA NA NA NA NA NA NA 13116 FUN_034456 14 0 33 0 59 NA NA NA NA NA NA NA 13117 FUN_034457 0 17 29 0 0 NA NA NA NA NA NA NA 13118 FUN_034450 420 15 227 20 494 ptg000024l:8975657-8986599 Q9DEI1 6.74e-46 DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) Xenopus laevis (African clawed frog) double-strand break repair via nonhomologous end joining [GO:0006303]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; phosphorylation [GO:0016310]; ribosome biogenesis [GO:0042254] GO:0004674; GO:0004677; GO:0005524; GO:0005730; GO:0006303; GO:0016310; GO:0031571; GO:0042254; GO:0070419; GO:0106310 13119 FUN_034450 420 15 227 20 494 ptg000024l:8975657-8986599 Q9DEI1 6.74e-46 DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) Xenopus laevis (African clawed frog) double-strand break repair via nonhomologous end joining [GO:0006303]; mitotic G1 DNA damage checkpoint signaling [GO:0031571]; phosphorylation [GO:0016310]; ribosome biogenesis [GO:0042254] GO:0004674; GO:0004677; GO:0005524; GO:0005730; GO:0006303; GO:0016310; GO:0031571; GO:0042254; GO:0070419; GO:0106310 13120 FUN_034451 30 0 41 0 84 NA NA NA NA NA NA NA 13121 FUN_000378 8010 4737 2307 5995 3703 ntLink_6:2235884-2242485 O57478 3.9e-22 Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase) Xenopus laevis (African clawed frog) heme biosynthetic process [GO:0006783] GO:0004325; GO:0005743; GO:0006783; GO:0046872; GO:0051537 13122 FUN_011210 0 0 0 0 122 NA NA NA NA NA NA NA 13123 FUN_002318 0 5 29 36 112 NA NA NA NA NA NA NA 13124 FUN_002319 2 2 6 16 23 NA NA NA NA NA NA NA 13125 FUN_002312 2 1 11 34 31 NA NA NA NA NA NA NA 13126 FUN_002313 4 8 14 33 41 NA NA NA NA NA NA NA 13127 FUN_002310 5 2 13 15 27 NA NA NA NA NA NA NA 13128 FUN_002311 7 13 121 112 432 NA NA NA NA NA NA NA 13129 FUN_002317 2 3 10 18 24 NA NA NA NA NA NA NA 13130 FUN_002314 8 12 96 25 318 NA NA NA NA NA NA NA 13131 FUN_000371 606 422 251 558 199 NA NA NA NA NA NA NA 13132 FUN_014568 12 0 20 0 81 NA NA NA NA NA NA NA 13133 FUN_014569 192 276 523 306 173 NA NA NA NA NA NA NA 13134 FUN_014567 2068 2330 1185 1806 1289 ptg000009l:1200262-1201878 P62323 2.45e-48 Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) Xenopus laevis (African clawed frog) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal snRNP assembly [GO:0000387] GO:0000387; GO:0000398; GO:0005634; GO:0005685; GO:0005687; GO:0005829; GO:0034709; GO:0034715; GO:0034719; GO:0046540; GO:0071005; GO:0071007; GO:0071208 13135 FUN_014564 2219 1538 1222 2064 1722 ptg000009l:1193405-1194769 P28344 3.79e-29 Malate synthase, glyoxysomal (EC 2.3.3.9) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) acetate catabolic process [GO:0045733]; carbon utilization [GO:0015976]; fatty acid catabolic process [GO:0009062]; glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004474; GO:0005737; GO:0005777; GO:0005782; GO:0006097; GO:0006099; GO:0009062; GO:0009514; GO:0015976; GO:0045733 13136 FUN_014563 7643 9255 6174 13357 13941 ptg000009l:1184306-1186616 Q9K9H0 5.03e-123 Isocitrate lyase (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004451; GO:0006097; GO:0006099; GO:0046872 13137 FUN_014563 7643 9255 6174 13357 13941 ptg000009l:1184306-1186616 Q9K9H0 3.6e-39 Isocitrate lyase (ICL) (EC 4.1.3.1) (Isocitrase) (Isocitratase) Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) glyoxylate cycle [GO:0006097]; tricarboxylic acid cycle [GO:0006099] GO:0004451; GO:0006097; GO:0006099; GO:0046872 13138 FUN_026361 55 0 52 132 86 NA NA NA NA NA NA NA 13139 FUN_026363 809 410 204 976 536 ptg000020l:8063686-8080058 Q9HBA9 3.32e-72 Putative N-acetylated-alpha-linked acidic dipeptidase (NAALADase) (EC 3.4.-.-) (Cell growth-inhibiting gene 26 protein) (Prostate-specific membrane antigen-like protein) (Putative folate hydrolase 1B) Homo sapiens (Human) C-terminal protein deglutamylation [GO:0035609]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005737; GO:0005886; GO:0006508; GO:0016805; GO:0035609; GO:0046872; GO:0070062 13140 FUN_026362 4689 924 1740 3716 1723 ptg000020l:8044146-8055133 Q9Y3Q0 3.76e-67 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 13141 FUN_026365 51 12 19 0 149 NA NA NA NA NA NA NA 13142 FUN_026364 28 31 0 0 27 NA NA NA NA NA NA NA 13143 FUN_026367 530 691 258 429 653 ptg000020l:8090958-8103614 P54277 8.1e-56 PMS1 protein homolog 1 (DNA mismatch repair protein PMS1) Homo sapiens (Human) mismatch repair [GO:0006298]; response to xenobiotic stimulus [GO:0009410] GO:0003677; GO:0005524; GO:0005634; GO:0006298; GO:0009410; GO:0016887; GO:0019899; GO:0030983; GO:0032300; GO:0140664 13144 FUN_026366 2508 1727 1184 1998 1019 NA NA NA NA NA NA NA 13145 FUN_026369 500 390 401 376 541 NA NA NA NA NA NA NA 13146 FUN_026368 16 0 18 15 22 NA NA NA NA NA NA NA 13147 FUN_022844 164 289 103 351 382 NA NA NA NA NA NA NA 13148 FUN_022845 0 0 0 0 49 NA NA NA NA NA NA NA 13149 FUN_022846 0 0 0 0 48 NA NA NA NA NA NA NA 13150 FUN_022847 424 333 1265 1014 245 NA NA NA NA NA NA NA 13151 FUN_022840 1482 124 0 151 5 NA NA NA NA NA NA NA 13152 FUN_022842 22 18 0 0 0 NA NA NA NA NA NA NA 13153 FUN_022843 128 87 208 223 100 NA NA NA NA NA NA NA 13154 FUN_022848 398 353 96 302 24 NA NA NA NA NA NA NA 13155 FUN_022849 0 101 54 95 70 NA NA NA NA NA NA NA 13156 FUN_029746 26 17 107 34 230 NA NA NA NA NA NA NA 13157 FUN_029744 0 0 84 79 2 NA NA NA NA NA NA NA 13158 FUN_029745 30 29 38 58 0 NA NA NA NA NA NA NA 13159 FUN_029742 800 395 113 308 475 NA NA NA NA NA NA NA 13160 FUN_029740 0 53 0 144 113 NA NA NA NA NA NA NA 13161 FUN_029741 59 6 0 0 0 NA NA NA NA NA NA NA 13162 FUN_029748 0 0 0 0 13 NA NA NA NA NA NA NA 13163 FUN_029749 12 15 0 0 0 NA NA NA NA NA NA NA 13164 FUN_023465 7 24 0 5 10 ptg000017l:7796434-7797415 Q4LBB9 4.85e-40 Octopamine receptor beta-2R (DmOct-beta-12) (DmOct-beta-2R) Drosophila melanogaster (Fruit fly) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; fertilization [GO:0009566]; G protein-coupled receptor signaling pathway [GO:0007186]; ovulation [GO:0030728]; positive regulation of synaptic assembly at neuromuscular junction [GO:0045887] GO:0003700; GO:0004930; GO:0004989; GO:0005886; GO:0007186; GO:0007189; GO:0008227; GO:0009566; GO:0016020; GO:0030728; GO:0045887; GO:0071880 13165 FUN_023464 22 0 13 9 204 NA NA NA NA NA NA NA 13166 FUN_023467 8 0 0 85 91 NA NA NA NA NA NA NA 13167 FUN_023466 0 12 0 0 135 NA NA NA NA NA NA NA 13168 FUN_023461 0 0 17 0 0 ptg000017l:7751663-7753827 Q91175 8.13e-34 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 13169 FUN_023460 14 0 3 0 15 ptg000017l:7746220-7750553 P56719 6e-23 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Rattus norvegicus (Rat) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 13170 FUN_023462 25 9 16 0 20 ptg000017l:7762826-7763843 P35368 3.53e-36 Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; neuron-glial cell signaling [GO:0150099]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007186; GO:0007188; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0035556; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880; GO:0150099 13171 FUN_023468 2 23 22 52 30 NA NA NA NA NA NA NA 13172 FUN_022598 46 23 36 210 110 ptg000016l:11183674-11184871 Q28997 3.99e-29 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Sus scrofa (Pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle contraction [GO:0006940] GO:0002032; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0006940; GO:0007189; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0051380; GO:0097746; GO:1901098; GO:1904504 13173 FUN_022599 7055 4799 3292 5578 3964 NA NA NA NA NA NA NA 13174 FUN_022596 734 539 405 529 426 ptg000016l:11118629-11123193 P47800 4.53e-42 D(1)-like dopamine receptor Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 13175 FUN_022594 780 339 404 375 463 NA NA NA NA NA NA NA 13176 FUN_022595 189 187 168 105 289 NA NA NA NA NA NA NA 13177 FUN_022593 1111 652 470 914 635 NA NA NA NA NA NA NA 13178 FUN_022590 0 11 0 6 0 NA NA NA NA NA NA NA 13179 FUN_022591 1839 594 645 1000 1052 ptg000016l:11058136-11074162 E2RG47 2.3e-23 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) Canis lupus familiaris (Dog) (Canis familiaris) co-translational protein modification [GO:0043686]; glycoprotein catabolic process [GO:0006516]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation via asparagine [GO:0018279]; response to unfolded protein [GO:0006986]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004579; GO:0006516; GO:0006986; GO:0018279; GO:0030433; GO:0034998; GO:0034999; GO:0043686; GO:0043687; GO:0046872 13180 FUN_006978 509 585 422 779 583 NA NA NA NA NA NA NA 13181 FUN_012747 86 30 56 70 155 NA NA NA NA NA NA NA 13182 FUN_004244 290 213 114 239 189 NA NA NA NA NA NA NA 13183 FUN_015381 559 179 166 608 156 NA NA NA NA NA NA NA 13184 FUN_015380 72 47 46 28 18 NA NA NA NA NA NA NA 13185 FUN_015383 187 561 249 152 308 NA NA NA NA NA NA NA 13186 FUN_015382 205 68 176 308 73 NA NA NA NA NA NA NA 13187 FUN_015385 21 0 0 33 0 NA NA NA NA NA NA NA 13188 FUN_015384 82 92 42 125 40 NA NA NA NA NA NA NA 13189 FUN_015387 1189 6087 2485 2610 4782 NA NA NA NA NA NA NA 13190 FUN_015389 290 116 7217 339 152 NA NA NA NA NA NA NA 13191 FUN_015388 585 438 301 427 494 ptg000009l:9626103-9632275 Q5ZKT8 2.7e-21 39S ribosomal protein L15, mitochondrial (L15mt) (MRP-L15) Gallus gallus (Chicken) translation [GO:0006412] GO:0003735; GO:0005762; GO:0006412 13192 FUN_017714 0 0 6 0 26 NA NA NA NA NA NA NA 13193 FUN_017715 12 7 35 4 186 NA NA NA NA NA NA NA 13194 FUN_017717 0 0 0 0 8 NA NA NA NA NA NA NA 13195 FUN_017710 145 715 105 251 216 ptg000011l:13505373-13509081 P0DXC0 2.51e-77 NA NA NA NA 13196 FUN_017711 3602 4846 3395 3598 2101 NA NA NA NA NA NA NA 13197 FUN_017712 2781 3406 1857 2392 1784 ptg000011l:13515978-13530487 Q5RF84 4.58e-22 Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to interferon-beta [GO:0035458]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004842; GO:0005524; GO:0005783; GO:0005811; GO:0030433; GO:0035458; GO:0061631; GO:0070936; GO:1904153 13198 FUN_017713 0 10 12 27 0 NA NA NA NA NA NA NA 13199 FUN_004322 25 14 27 29 23 NA NA NA NA NA NA NA 13200 FUN_025108 6281 4295 3076 5528 5292 NA NA NA NA NA NA NA 13201 FUN_025109 14487 20755 8424 7798 6101 NA NA NA NA NA NA NA 13202 FUN_022338 17 9 8 15 46 NA NA NA NA NA NA NA 13203 FUN_022339 21 17 4 5 38 NA NA NA NA NA NA NA 13204 FUN_022332 1212 724 600 1201 977 NA NA NA NA NA NA NA 13205 FUN_022330 2833 835 1012 2200 1841 NA NA NA NA NA NA NA 13206 FUN_025104 0 0 17 0 0 NA NA NA NA NA NA NA 13207 FUN_022337 39 10 0 6 29 NA NA NA NA NA NA NA 13208 FUN_022334 227 107 169 67 216 NA NA NA NA NA NA NA 13209 FUN_022335 22 14 19 12 8 NA NA NA NA NA NA NA 13210 FUN_024859 0 29 0 18 3 NA NA NA NA NA NA NA 13211 FUN_011564 1 0 3 11 0 NA NA NA NA NA NA NA 13212 FUN_024855 0 0 0 0 16 NA NA NA NA NA NA NA 13213 FUN_024856 5 0 14 0 0 NA NA NA NA NA NA NA 13214 FUN_043001 481 396 324 548 319 NA NA NA NA NA NA NA 13215 FUN_043000 244 72 129 171 134 NA NA NA NA NA NA NA 13216 FUN_043002 288 58 500 209 510 NA NA NA NA NA NA NA 13217 FUN_019653 0 0 0 16 0 NA NA NA NA NA NA NA 13218 FUN_019650 0 0 23 0 84 NA NA NA NA NA NA NA 13219 FUN_044185 3 23 41 35 105 NA NA NA NA NA NA NA 13220 FUN_044186 1 0 4 4 11 NA NA NA NA NA NA NA 13221 FUN_044181 3 0 5 6 16 NA NA NA NA NA NA NA 13222 FUN_044180 7 8 72 23 136 NA NA NA NA NA NA NA 13223 FUN_044183 2 2 10 8 11 NA NA NA NA NA NA NA 13224 FUN_044182 4 4 59 41 120 NA NA NA NA NA NA NA 13225 FUN_044189 0 1 4 3 9 NA NA NA NA NA NA NA 13226 FUN_044188 5 10 53 32 168 NA NA NA NA NA NA NA 13227 FUN_024278 0 0 0 0 6 NA NA NA NA NA NA NA 13228 FUN_024271 19 141 209 165 69 NA NA NA NA NA NA NA 13229 FUN_024270 16 40 12 50 12 ptg000018l:4211305-4219120 P59046 2.27e-47 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 13230 FUN_024273 15 205 143 234 156 NA NA NA NA NA NA NA 13231 FUN_024272 85 78 38 40 44 ptg000018l:4243762-4248568 Q8R4B8 2.04e-41 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002221; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006919; GO:0006954; GO:0007231; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070269; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 13232 FUN_024275 0 25 38 0 70 NA NA NA NA NA NA NA 13233 FUN_024274 29 25 20 12 24 ptg000018l:4269165-4272768 B0FPE9 9.98e-44 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Macaca mulatta (Rhesus macaque) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 13234 FUN_024277 26 32 13 101 14 NA NA NA NA NA NA NA 13235 FUN_044239 2 4 11 2 97 NA NA NA NA NA NA NA 13236 FUN_030109 1 0 0 9 2 NA NA NA NA NA NA NA 13237 FUN_044236 12 28 29 37 89 NA NA NA NA NA NA NA 13238 FUN_044235 7 14 15 18 42 NA NA NA NA NA NA NA 13239 FUN_044234 0 0 1 0 9 NA NA NA NA NA NA NA 13240 FUN_030102 0 7 0 0 0 NA NA NA NA NA NA NA 13241 FUN_030103 38 39 54 61 93 NA NA NA NA NA NA NA 13242 FUN_030100 0 0 0 0 19 NA NA NA NA NA NA NA 13243 FUN_044230 0 34 0 0 36 NA NA NA NA NA NA NA 13244 FUN_038378 1707 1097 557 1278 1340 NA NA NA NA NA NA NA 13245 FUN_038375 1971 1004 779 1535 1588 NA NA NA NA NA NA NA 13246 FUN_038374 166 162 184 307 252 ptg000027l:6372700-6373423 Q9YHV3 4.35e-37 Noggin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cartilage development [GO:0051216]; cloaca development [GO:0035844]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic viscerocranium morphogenesis [GO:0048703]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell differentiation [GO:0045596]; osteoblast differentiation [GO:0001649]; pronephros development [GO:0048793] GO:0001649; GO:0005615; GO:0007368; GO:0009953; GO:0030514; GO:0035844; GO:0045596; GO:0048703; GO:0048793; GO:0051216 13247 FUN_038377 2897 3331 1233 1791 1324 NA NA NA NA NA NA NA 13248 FUN_038376 1128 612 536 875 733 NA NA NA NA NA NA NA 13249 FUN_038371 301 183 280 385 339 NA NA NA NA NA NA NA 13250 FUN_038370 712 427 375 807 883 NA NA NA NA NA NA NA 13251 FUN_038373 2320 2936 1656 2001 1171 NA NA NA NA NA NA NA 13252 FUN_038372 251 158 209 320 132 NA NA NA NA NA NA NA 13253 FUN_039423 10 0 4 28 5 NA NA NA NA NA NA NA 13254 FUN_039420 1807 574 145 1681 439 ptg000029c:1654926-1668206 Q7RTR2 2.96e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13255 FUN_039420 1807 574 145 1681 439 ptg000029c:1654926-1668206 Q7RTR2 4.21e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13256 FUN_039420 1807 574 145 1681 439 ptg000029c:1654926-1668206 Q7RTR2 3.37e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13257 FUN_039420 1807 574 145 1681 439 ptg000029c:1654926-1668206 Q7RTR2 7.21e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13258 FUN_039420 1807 574 145 1681 439 ptg000029c:1654926-1668206 Q7RTR2 8.16e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 13259 FUN_039427 41 16 0 35 8 NA NA NA NA NA NA NA 13260 FUN_039428 55 105 248 5 227 NA NA NA NA NA NA NA 13261 FUN_039429 67 359 37 0 16 NA NA NA NA NA NA NA 13262 FUN_001202 13 0 18 0 73 ntLink_6:9727048-9732833 Q8BM14 7.47e-28 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Mus musculus (Mouse) lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016788; GO:0043231 13263 FUN_001205 107 34 0 60 13 ntLink_6:9770394-9775062 Q5VXJ0 1.93e-48 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 13264 FUN_001205 107 34 0 60 13 ntLink_6:9770394-9775062 Q5VXJ0 1.93e-48 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 13265 FUN_001204 8267 4179 7449 4750 5337 ntLink_6:9760494-9764836 Q5VXJ0 2.66e-28 Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2) Homo sapiens (Human) cornification [GO:0070268]; lipid catabolic process [GO:0016042] GO:0004465; GO:0005576; GO:0016042; GO:0043231; GO:0070268 13266 FUN_001207 3889 2707 1697 2802 2804 ntLink_6:9781305-9804024 Q4R6F8 3.01e-23 T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005524; GO:0005832; GO:0016887; GO:0051082; GO:0140662 13267 FUN_036136 0 2 13 0 0 ptg000025l:15660704-15661487 P84239 1.37e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13268 FUN_026235 318 59 102 133 36 ptg000020l:6539940-6568660 Q54KA7 1.7e-26 Ankyrin repeat, PH and SEC7 domain containing protein secG Dictyostelium discoideum (Social amoeba) actin cytoskeleton organization [GO:0030036]; cell-substrate adhesion [GO:0031589]; chemotaxis [GO:0006935]; chemotaxis to cAMP [GO:0043327]; culmination involved in sorocarp development [GO:0031154]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005764; GO:0005829; GO:0006935; GO:0030036; GO:0031154; GO:0031589; GO:0032012; GO:0043327 13269 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.57e-99 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13270 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.25e-97 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13271 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 3.97e-96 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13272 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.16e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13273 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.42e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13274 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 3.76e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13275 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 4.44e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13276 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 8.72e-93 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13277 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.76e-90 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13278 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.39e-85 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13279 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.92e-84 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13280 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.25e-74 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13281 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.12e-64 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13282 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 3.97e-63 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13283 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 6.71e-63 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13284 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.62e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13285 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.91e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13286 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 5.86e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13287 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 6.33e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13288 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.05e-58 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13289 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 6.09e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13290 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.83e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13291 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.54e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13292 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.14e-51 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13293 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 7.34e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13294 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 3.35e-37 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13295 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 9.96e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13296 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.33e-35 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13297 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 3.6e-35 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13298 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.35e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13299 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 9.22e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13300 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 9.3e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13301 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 5.01e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13302 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 4.12e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13303 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 7.21e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13304 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.08e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13305 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 4.78e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13306 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.2e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13307 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 2.52e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13308 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 1.16e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13309 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 4.96e-27 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13310 FUN_027779 332 96 126 534 570 ptg000021l:10683757-10722181 P10079 3.36e-26 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13311 FUN_027778 88 68 95 148 188 ptg000021l:10648385-10672367 C0HL13 1.91e-27 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 13312 FUN_027778 88 68 95 148 188 ptg000021l:10648385-10672367 C0HL13 6.81e-26 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 13313 FUN_027778 88 68 95 148 188 ptg000021l:10648385-10672367 C0HL13 1.2e-24 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 13314 FUN_027777 6 0 8 0 0 NA NA NA NA NA NA NA 13315 FUN_038598 11 0 0 0 0 NA NA NA NA NA NA NA 13316 FUN_025721 0 0 0 14 0 NA NA NA NA NA NA NA 13317 FUN_038591 0 0 9 0 51 NA NA NA NA NA NA NA 13318 FUN_038593 0 0 0 0 17 NA NA NA NA NA NA NA 13319 FUN_038592 0 0 0 4 14 NA NA NA NA NA NA NA 13320 FUN_038595 15 0 14 5 38 NA NA NA NA NA NA NA 13321 FUN_022110 3046 2341 1115 4655 3552 NA NA NA NA NA NA NA 13322 FUN_038597 0 27 21 0 0 NA NA NA NA NA NA NA 13323 FUN_036138 93 94 48 55 29 ptg000025l:15665957-15668871 Q6PC60 6.51e-53 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 13324 FUN_025723 7973 9536 4788 12254 3885 ptg000020l:108871-124486 Q14566 5.82e-32 DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM) Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication [GO:1902969]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0006260; GO:0006268; GO:0006270; GO:0016887; GO:0030174; GO:0042555; GO:0042802; GO:0071162; GO:1902969 13325 FUN_025723 7973 9536 4788 12254 3885 ptg000020l:108871-124486 Q14566 5.82e-32 DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM) Homo sapiens (Human) DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication [GO:1902969]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0006260; GO:0006268; GO:0006270; GO:0016887; GO:0030174; GO:0042555; GO:0042802; GO:0071162; GO:1902969 13326 FUN_036628 37 5 0 5 10 NA NA NA NA NA NA NA 13327 FUN_036627 11 0 19 0 12 NA NA NA NA NA NA NA 13328 FUN_037573 4598 2566 2747 3634 3247 ptg000026l:11925692-11934635 O42586 5.35e-24 26S proteasome regulatory subunit 6A-B (26S proteasome AAA-ATPase subunit RPT5-B) (Proteasome 26S subunit ATPase 3-B) (Tat-binding protein 10) (TBP-10) Xenopus laevis (African clawed frog) protein catabolic process [GO:0030163] GO:0005524; GO:0005634; GO:0005737; GO:0016887; GO:0022624; GO:0030163; GO:0036402 13329 FUN_037570 692 432 311 666 370 NA NA NA NA NA NA NA 13330 FUN_037571 4 7 0 27 0 NA NA NA NA NA NA NA 13331 FUN_037576 39 37 5 42 50 NA NA NA NA NA NA NA 13332 FUN_037577 57 16 8 26 69 NA NA NA NA NA NA NA 13333 FUN_037574 249 236 161 595 289 NA NA NA NA NA NA NA 13334 FUN_037575 214 297 65 277 101 ptg000026l:11946484-11951868 O64411 4.18e-30 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 13335 FUN_037578 301 0 185 0 181 NA NA NA NA NA NA NA 13336 FUN_022115 18 3 17 7 0 ptg000016l:5639249-5647210 B8UU78 4.24e-161 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13337 FUN_022115 18 3 17 7 0 ptg000016l:5639249-5647210 B8UU78 8.46e-161 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13338 FUN_022115 18 3 17 7 0 ptg000016l:5639249-5647210 B8UU78 2.59e-28 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13339 FUN_022115 18 3 17 7 0 ptg000016l:5639249-5647210 B8UU78 1.42e-24 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13340 FUN_037848 548 257 344 431 232 ptg000026l:14363378-14365452 Q6N075 1.35e-122 Molybdate-anion transporter (Major facilitator superfamily domain-containing protein 5) (Molybdate transporter 2 homolog) (hsMOT2) Homo sapiens (Human) NA GO:0005886; GO:0015098; GO:0016020 13341 FUN_036197 0 1 1 0 8 NA NA NA NA NA NA NA 13342 FUN_036196 612 227 269 376 355 ptg000025l:16390202-16393261 Q2TBL8 1.77e-73 Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) Bos taurus (Bovine) cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of mitotic cell cycle [GO:0007346] GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0007346; GO:0018107; GO:0030030; GO:0032956; GO:0036064; GO:0043410; GO:0106310; GO:1902018 13343 FUN_036196 612 227 269 376 355 ptg000025l:16390202-16393261 Q2TBL8 1.34e-66 Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) Bos taurus (Bovine) cell projection organization [GO:0030030]; negative regulation of cilium assembly [GO:1902018]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of MAPK cascade [GO:0043410]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of mitotic cell cycle [GO:0007346] GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0007346; GO:0018107; GO:0030030; GO:0032956; GO:0036064; GO:0043410; GO:0106310; GO:1902018 13344 FUN_036195 5470 3097 2540 5326 4109 ptg000025l:16349926-16386123 P04323 2.19e-21 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 13345 FUN_036195 5470 3097 2540 5326 4109 ptg000025l:16349926-16386123 P04323 2.19e-21 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 13346 FUN_036194 118 66 38 154 81 NA NA NA NA NA NA NA 13347 FUN_036193 1453 509 660 904 703 NA NA NA NA NA NA NA 13348 FUN_036192 72 48 140 818 302 ptg000025l:16331395-16334283 E7FAM5 0 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 13349 FUN_036190 19 11 0 0 14 NA NA NA NA NA NA NA 13350 FUN_036199 2 2 0 1 6 NA NA NA NA NA NA NA 13351 FUN_027198 61 7 14 15 187 NA NA NA NA NA NA NA 13352 FUN_024450 1489 793 459 950 789 ptg000018l:6512105-6523052 Q9TTU3 9.85e-43 H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) Oryctolagus cuniculus (Rabbit) NA GO:0000139; GO:0005247; GO:0005524; GO:0005886; GO:0010008; GO:0015297 13353 FUN_024450 1489 793 459 950 789 ptg000018l:6512105-6523052 Q9TTU3 4.28e-25 H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) Oryctolagus cuniculus (Rabbit) NA GO:0000139; GO:0005247; GO:0005524; GO:0005886; GO:0010008; GO:0015297 13354 FUN_024450 1489 793 459 950 789 ptg000018l:6512105-6523052 Q9TTU3 1.27e-23 H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5) Oryctolagus cuniculus (Rabbit) NA GO:0000139; GO:0005247; GO:0005524; GO:0005886; GO:0010008; GO:0015297 13355 FUN_027192 0 0 0 0 39 NA NA NA NA NA NA NA 13356 FUN_027197 14 0 0 0 0 NA NA NA NA NA NA NA 13357 FUN_006767 30 0 0 109 93 NA NA NA NA NA NA NA 13358 FUN_006766 68 46 53 50 74 NA NA NA NA NA NA NA 13359 FUN_006764 0 0 12 0 75 NA NA NA NA NA NA NA 13360 FUN_006763 58 137 137 74 79 NA NA NA NA NA NA NA 13361 FUN_006762 218 400 796 198 342 NA NA NA NA NA NA NA 13362 FUN_006761 0 0 0 0 21 NA NA NA NA NA NA NA 13363 FUN_006760 0 0 0 0 6 NA NA NA NA NA NA NA 13364 FUN_024455 268 234 186 753 349 NA NA NA NA NA NA NA 13365 FUN_006769 2810 6229 2528 9393 6514 NA NA NA NA NA NA NA 13366 FUN_008063 95 42 45 75 18 NA NA NA NA NA NA NA 13367 FUN_026822 0 0 14 0 11 NA NA NA NA NA NA NA 13368 FUN_026820 0 49 0 0 0 ptg000020l:13816873-13817893 Q8BSL4 3.25e-83 Heparan sulfate glucosamine 3-O-sulfotransferase 5 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5) (Heparan sulfate 3-O-sulfotransferase 5) Mus musculus (Mouse) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015]; negative regulation of coagulation [GO:0050819]; protein sulfation [GO:0006477]; regulation of viral entry into host cell [GO:0046596] GO:0000139; GO:0006477; GO:0008467; GO:0015012; GO:0015015; GO:0046596; GO:0050819 13369 FUN_026821 313 132 182 205 348 NA NA NA NA NA NA NA 13370 FUN_026826 1255 1594 760 1191 884 ptg000020l:13915059-13943611 P35061 4.65e-39 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13371 FUN_008060 2567 1566 1219 1484 967 NA NA NA NA NA NA NA 13372 FUN_026824 0 4 0 0 25 NA NA NA NA NA NA NA 13373 FUN_026828 41 80 0 0 8 NA NA NA NA NA NA NA 13374 FUN_026829 0 0 0 0 18 NA NA NA NA NA NA NA 13375 FUN_032625 50 29 29 0 99 NA NA NA NA NA NA NA 13376 FUN_029554 1644 920 530 1269 1108 NA NA NA NA NA NA NA 13377 FUN_032624 86 78 67 8 20 NA NA NA NA NA NA NA 13378 FUN_008069 12 2016 52 157 58 NA NA NA NA NA NA NA 13379 FUN_031712 415 113 254 788 353 ptg000023l:24652561-24655320 E7FAM5 3.16e-96 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 13380 FUN_014377 40 0 0 21 0 NA NA NA NA NA NA NA 13381 FUN_029558 86 0 0 0 18 NA NA NA NA NA NA NA 13382 FUN_044055 2 0 9 1 49 NA NA NA NA NA NA NA 13383 FUN_044053 4 5 17 2 106 NA NA NA NA NA NA NA 13384 FUN_044052 57 106 117 103 281 NA NA NA NA NA NA NA 13385 FUN_044051 237 803 1403 675 498 NA NA NA NA NA NA NA 13386 FUN_044050 252 1072 2594 595 545 NA NA NA NA NA NA NA 13387 FUN_026267 0 0 0 43 0 NA NA NA NA NA NA NA 13388 FUN_005529 927 299 283 376 305 NA NA NA NA NA NA NA 13389 FUN_001234 4001 8323 2622 4213 2745 ntLink_6:10091673-10102030 Q5R9C7 8.89e-34 Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) signal peptide processing [GO:0006465] GO:0004252; GO:0005787; GO:0006465 13390 FUN_001234 4001 8323 2622 4213 2745 ntLink_6:10091673-10102030 Q5R9C7 8.89e-34 Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) signal peptide processing [GO:0006465] GO:0004252; GO:0005787; GO:0006465 13391 FUN_001235 4391 3390 2248 4697 4066 ntLink_6:10104556-10114024 Q60520 2.41e-24 Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a) Mus musculus (Mouse) activation of innate immune response [GO:0002218]; aging [GO:0007568]; cellular response to dopamine [GO:1903351]; cellular response to glucose stimulus [GO:0071333]; cerebral cortex neuron differentiation [GO:0021895]; DNA replication [GO:0006260]; hematopoietic progenitor cell differentiation [GO:0002244]; histone deacetylation [GO:0016575]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell migration [GO:0030336]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of histone H3-K27 acetylation [GO:1901675]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of heterochromatin formation [GO:0031453]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; protein localization [GO:0008104]; regulation of axon extension [GO:0030516]; regulation of DNA-templated transcription [GO:0006355]; regulation of hormone levels [GO:0010817]; regulation of transcription from RNA polymerase II promoter in response to oxidative stress [GO:0043619]; response to methylglyoxal [GO:0051595]; response to organonitrogen compound [GO:0010243]; rhythmic process [GO:0048511] GO:0000118; GO:0000122; GO:0000776; GO:0000785; GO:0001701; GO:0002218; GO:0002230; GO:0002244; GO:0003677; GO:0003682; GO:0003713; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005730; GO:0006260; GO:0006355; GO:0006476; GO:0007568; GO:0008104; GO:0010243; GO:0010817; GO:0010971; GO:0016575; GO:0016580; GO:0017053; GO:0021895; GO:0030336; GO:0030512; GO:0030516; GO:0031453; GO:0032991; GO:0042754; GO:0043066; GO:0043619; GO:0044877; GO:0045666; GO:0045892; GO:0045944; GO:0048511; GO:0051595; GO:0061629; GO:0071333; GO:0140416; GO:1900181; GO:1901675; GO:1902455; GO:1902459; GO:1903351; GO:2000678 13392 FUN_001236 1404 1515 985 1149 857 NA NA NA NA NA NA NA 13393 FUN_001237 401 157 275 222 175 NA NA NA NA NA NA NA 13394 FUN_001230 4006 2354 2091 3399 3264 NA NA NA NA NA NA NA 13395 FUN_001231 37 11 41 3 104 NA NA NA NA NA NA NA 13396 FUN_001232 669 529 553 657 715 NA NA NA NA NA NA NA 13397 FUN_001233 971 736 461 664 455 ntLink_6:10083265-10087755 Q5ZKF4 2.14e-21 High mobility group protein 20A (HMG box-containing protein 20A) Gallus gallus (Chicken) regulation of gene expression [GO:0010468] GO:0003677; GO:0005634; GO:0010468 13398 FUN_001238 2241 571 457 1239 949 NA NA NA NA NA NA NA 13399 FUN_001239 95 26 0 125 77 NA NA NA NA NA NA NA 13400 FUN_033476 6 0 3 1 38 NA NA NA NA NA NA NA 13401 FUN_033474 34 0 15 1 140 NA NA NA NA NA NA NA 13402 FUN_033478 2 0 2 0 7 NA NA NA NA NA NA NA 13403 FUN_025845 2967 1531 1839 2903 1816 NA NA NA NA NA NA NA 13404 FUN_025844 4623 2224 1995 2937 4595 NA NA NA NA NA NA NA 13405 FUN_025847 351 248 138 211 260 ptg000020l:1263423-1264204 Q8BXK9 5.21e-24 Chloride intracellular channel protein 5 Mus musculus (Mouse) auditory receptor cell stereocilium organization [GO:0060088]; chloride transport [GO:0006821]; diet induced thermogenesis [GO:0002024]; neuromuscular process controlling balance [GO:0050885]; protein localization [GO:0008104]; regulation of ion transmembrane transport [GO:0034765]; response to dietary excess [GO:0002021]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0002021; GO:0002024; GO:0005244; GO:0005254; GO:0005737; GO:0005794; GO:0005815; GO:0005886; GO:0005938; GO:0006821; GO:0007601; GO:0007605; GO:0008104; GO:0015629; GO:0016020; GO:0016324; GO:0032420; GO:0032421; GO:0034707; GO:0034765; GO:0050885; GO:0060088 13406 FUN_025846 539 12 988 769 368 NA NA NA NA NA NA NA 13407 FUN_025841 1726 1390 845 1370 1028 ptg000020l:1193764-1200261 Q6DJR8 3.15e-66 Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593] GO:0000139; GO:0004653; GO:0005112; GO:0007220; GO:0007368; GO:0008593; GO:0018243; GO:0030246; GO:0060271; GO:0061314 13408 FUN_025841 1726 1390 845 1370 1028 ptg000020l:1193764-1200261 Q6DJR8 1.25e-30 Polypeptide N-acetylgalactosaminyltransferase 11 (EC 2.4.1.41) (Polypeptide GalNAc transferase 11) (GalNAc-T11) (pp-GaNTase 11) (Protein-UDP acetylgalactosaminyltransferase 11) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; Notch receptor processing [GO:0007220]; Notch signaling involved in heart development [GO:0061314]; protein O-linked glycosylation via threonine [GO:0018243]; regulation of Notch signaling pathway [GO:0008593] GO:0000139; GO:0004653; GO:0005112; GO:0007220; GO:0007368; GO:0008593; GO:0018243; GO:0030246; GO:0060271; GO:0061314 13409 FUN_025840 68135 49244 25161 36944 28885 ptg000020l:1185253-1192978 Q0QEP2 5.94e-56 ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) Mesocricetus auratus (Golden hamster) NA GO:0005524; GO:0005739; GO:0005753; GO:0045261; GO:0046933; GO:0046961 13410 FUN_025840 68135 49244 25161 36944 28885 ptg000020l:1185253-1192978 Q0QEP2 1.88e-34 ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) Mesocricetus auratus (Golden hamster) NA GO:0005524; GO:0005739; GO:0005753; GO:0045261; GO:0046933; GO:0046961 13411 FUN_025840 68135 49244 25161 36944 28885 ptg000020l:1185253-1192978 Q0QEP2 2.14e-24 ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) Mesocricetus auratus (Golden hamster) NA GO:0005524; GO:0005739; GO:0005753; GO:0045261; GO:0046933; GO:0046961 13412 FUN_025843 2917 3428 4189 5802 2106 NA NA NA NA NA NA NA 13413 FUN_025842 2830 2083 1863 2032 1718 NA NA NA NA NA NA NA 13414 FUN_025848 114 120 135 111 161 ptg000020l:1267021-1268359 Q8K2J9 6.37e-112 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 13415 FUN_009585 35 12 21 2 58 NA NA NA NA NA NA NA 13416 FUN_038418 10021 9940 6883 16106 16948 ptg000027l:6975267-6989103 Q501J6 8.71e-51 Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; defense response to virus [GO:0051607]; epithelial to mesenchymal transition [GO:0001837]; gene expression [GO:0010467]; immune system process [GO:0002376]; intracellular estrogen receptor signaling pathway [GO:0030520]; miRNA metabolic process [GO:0010586]; miRNA transcription [GO:0061614]; myoblast differentiation [GO:0045445]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA-mediated gene silencing [GO:0031047]; rRNA processing [GO:0006364] GO:0000380; GO:0000381; GO:0001837; GO:0002376; GO:0003713; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0005829; GO:0006357; GO:0006364; GO:0010467; GO:0010586; GO:0016607; GO:0016887; GO:0030520; GO:0030521; GO:0031047; GO:0031490; GO:0045445; GO:0045944; GO:0051607; GO:0061614; GO:0106222; GO:1990904; GO:2001014 13417 FUN_038418 10021 9940 6883 16106 16948 ptg000027l:6975267-6989103 Q501J6 5.33e-24 Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; androgen receptor signaling pathway [GO:0030521]; defense response to virus [GO:0051607]; epithelial to mesenchymal transition [GO:0001837]; gene expression [GO:0010467]; immune system process [GO:0002376]; intracellular estrogen receptor signaling pathway [GO:0030520]; miRNA metabolic process [GO:0010586]; miRNA transcription [GO:0061614]; myoblast differentiation [GO:0045445]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of skeletal muscle cell differentiation [GO:2001014]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA-mediated gene silencing [GO:0031047]; rRNA processing [GO:0006364] GO:0000380; GO:0000381; GO:0001837; GO:0002376; GO:0003713; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0005829; GO:0006357; GO:0006364; GO:0010467; GO:0010586; GO:0016607; GO:0016887; GO:0030520; GO:0030521; GO:0031047; GO:0031490; GO:0045445; GO:0045944; GO:0051607; GO:0061614; GO:0106222; GO:1990904; GO:2001014 13418 FUN_018243 40 0 0 2 3 NA NA NA NA NA NA NA 13419 FUN_018242 697 246 18 313 273 ptg000012l:6547181-6547970 Q8IZH2 3.85e-45 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 13420 FUN_018242 697 246 18 313 273 ptg000012l:6547181-6547970 Q8IZH2 7.61e-34 5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog) Homo sapiens (Human) cellular response to cycloheximide [GO:0071409]; cellular response to puromycin [GO:1905795]; histone mRNA catabolic process [GO:0071044]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of translation [GO:0017148]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; response to testosterone [GO:0033574]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; rRNA catabolic process [GO:0016075] GO:0000932; GO:0000956; GO:0002151; GO:0003723; GO:0004534; GO:0005634; GO:0005829; GO:0005886; GO:0016020; GO:0016075; GO:0017148; GO:0030425; GO:0032211; GO:0033574; GO:0043025; GO:0045202; GO:0051880; GO:0070034; GO:0071028; GO:0071044; GO:0071409; GO:0090503; GO:1905795 13421 FUN_018241 46 11 0 112 44 NA NA NA NA NA NA NA 13422 FUN_018240 36 17 0 60 26 NA NA NA NA NA NA NA 13423 FUN_018246 4 0 1 25 22 NA NA NA NA NA NA NA 13424 FUN_007968 30 3 20 39 4 NA NA NA NA NA NA NA 13425 FUN_007969 131 32 49 48 47 NA NA NA NA NA NA NA 13426 FUN_007966 0 41 11 63 0 NA NA NA NA NA NA NA 13427 FUN_007967 896 1122 446 628 502 NA NA NA NA NA NA NA 13428 FUN_007964 3612 4294 2964 3094 1741 ptg000002l:6623713-6628250 Q9GKX6 1.15e-22 Galactose mutarotase (EC 5.1.3.3) (Aldose 1-epimerase) Sus scrofa (Pig) galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006] GO:0004034; GO:0005737; GO:0006006; GO:0030246; GO:0033499 13429 FUN_007964 3612 4294 2964 3094 1741 ptg000002l:6623713-6628250 Q9GKX6 1.15e-22 Galactose mutarotase (EC 5.1.3.3) (Aldose 1-epimerase) Sus scrofa (Pig) galactose catabolic process via UDP-galactose [GO:0033499]; glucose metabolic process [GO:0006006] GO:0004034; GO:0005737; GO:0006006; GO:0030246; GO:0033499 13430 FUN_018248 0 0 3 0 35 NA NA NA NA NA NA NA 13431 FUN_007962 42 37 81 185 59 NA NA NA NA NA NA NA 13432 FUN_007963 2284 3747 1375 2622 1295 NA NA NA NA NA NA NA 13433 FUN_007960 2316 1467 999 2604 1785 NA NA NA NA NA NA NA 13434 FUN_007961 140 76 93 232 176 ptg000002l:6596827-6599120 P11275 1.42e-38 Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17) Rattus norvegicus (Rat) angiotensin-activated signaling pathway [GO:0038166]; calcium ion transport [GO:0006816]; calmodulin dependent kinase signaling pathway [GO:0099004]; cellular response to interferon-beta [GO:0035458]; dendrite morphogenesis [GO:0048813]; dendritic spine development [GO:0060996]; G1/S transition of mitotic cell cycle [GO:0000082]; ionotropic glutamate receptor signaling pathway [GO:0035235]; negative regulation of hydrolase activity [GO:0051346]; NMDA selective glutamate receptor signaling pathway [GO:0098989]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of endocannabinoid signaling pathway [GO:2000124]; regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902108]; regulation of neuron migration [GO:2001222]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of neurotransmitter secretion [GO:0046928]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of synaptic vesicle docking [GO:0099148]; response to ischemia [GO:0002931] GO:0000082; GO:0002931; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005954; GO:0006468; GO:0006816; GO:0009931; GO:0010666; GO:0014069; GO:0016020; GO:0016301; GO:0018105; GO:0030424; GO:0030425; GO:0032794; GO:0032839; GO:0035235; GO:0035254; GO:0035458; GO:0038166; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0045202; GO:0046427; GO:0046777; GO:0046872; GO:0046928; GO:0048168; GO:0048813; GO:0051092; GO:0051346; GO:0051928; GO:0060996; GO:0098685; GO:0098696; GO:0098970; GO:0098978; GO:0098989; GO:0099004; GO:0099148; GO:0099523; GO:0099524; GO:0099573; GO:0099634; GO:0106310; GO:1902108; GO:1903076; GO:1990443; GO:2000124; GO:2001222 13435 FUN_034124 420 322 403 898 341 ptg000024l:5143044-5148459 Q9NZV8 1.45e-39 Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2) Homo sapiens (Human) action potential [GO:0001508]; cellular response to hypoxia [GO:0071456]; chemical synaptic transmission [GO:0007268]; locomotor rhythm [GO:0045475]; neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0001508; GO:0005249; GO:0005250; GO:0005886; GO:0007268; GO:0008076; GO:0014069; GO:0016020; GO:0019228; GO:0019233; GO:0032809; GO:0034765; GO:0043197; GO:0043204; GO:0044853; GO:0045211; GO:0045475; GO:0046872; GO:0051260; GO:0070161; GO:0071456; GO:0071805; GO:0098978; GO:0098982; GO:0099634; GO:1905030 13436 FUN_034125 290 223 296 536 320 NA NA NA NA NA NA NA 13437 FUN_034126 50 60 19 73 29 NA NA NA NA NA NA NA 13438 FUN_034127 848 354 222 248 419 ptg000024l:5182044-5192787 Q9NBX4 3.76e-39 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 13439 FUN_034120 1459 861 807 1080 1093 ptg000024l:5093121-5109230 P28812 5.07e-33 Uncharacterized protein PA3568 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) NA GO:0050218 13440 FUN_034120 1459 861 807 1080 1093 ptg000024l:5093121-5109230 P28812 5.07e-33 Uncharacterized protein PA3568 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) NA GO:0050218 13441 FUN_034120 1459 861 807 1080 1093 ptg000024l:5093121-5109230 P28812 5.07e-33 Uncharacterized protein PA3568 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) NA GO:0050218 13442 FUN_034121 2151 1277 985 1316 1348 NA NA NA NA NA NA NA 13443 FUN_034122 78 65 50 122 95 NA NA NA NA NA NA NA 13444 FUN_034123 215 83 239 494 320 ptg000024l:5131536-5138404 Q9NSA2 3.92e-67 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 13445 FUN_034128 156 141 200 204 232 ptg000024l:5201506-5205143 Q9JJK4 1.86e-57 Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3) Rattus norvegicus (Rat) peroxisome membrane biogenesis [GO:0016557]; peroxisome organization [GO:0007031]; protein import into peroxisome membrane [GO:0045046] GO:0005777; GO:0005778; GO:0005783; GO:0005829; GO:0007031; GO:0008289; GO:0016020; GO:0016557; GO:0030674; GO:0032991; GO:0032994; GO:0045046 13446 FUN_034129 6434 4523 2795 2501 1698 NA NA NA NA NA NA NA 13447 FUN_042359 242 15 27 196 14 NA NA NA NA NA NA NA 13448 FUN_038419 1301 1395 916 1388 546 NA NA NA NA NA NA NA 13449 FUN_032705 0 0 0 0 19 NA NA NA NA NA NA NA 13450 FUN_042352 0 0 6 0 10 NA NA NA NA NA NA NA 13451 FUN_016030 78 49 143 406 287 NA NA NA NA NA NA NA 13452 FUN_016031 2460 1861 2227 3867 2389 NA NA NA NA NA NA NA 13453 FUN_043458 179 6 0 9 0 NA NA NA NA NA NA NA 13454 FUN_043459 3202 1908 1033 1542 891 NA NA NA NA NA NA NA 13455 FUN_043456 1667 2197 1531 1689 659 NA NA NA NA NA NA NA 13456 FUN_043457 39 3 16 6 0 NA NA NA NA NA NA NA 13457 FUN_043454 61 0 0 31 0 NA NA NA NA NA NA NA 13458 FUN_043455 839 438 558 533 411 NA NA NA NA NA NA NA 13459 FUN_043452 915 250 106 784 95 NA NA NA NA NA NA NA 13460 FUN_043453 0 0 44 0 0 NA NA NA NA NA NA NA 13461 FUN_016037 4679 3766 2766 5621 5917 NA NA NA NA NA NA NA 13462 FUN_016035 0 0 29 3 2 ptg000010l:923106-923886 Q2Q1W2 7.37e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 13463 FUN_016035 0 0 29 3 2 ptg000010l:923106-923886 Q2Q1W2 3.4e-37 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 13464 FUN_016035 0 0 29 3 2 ptg000010l:923106-923886 Q2Q1W2 1.01e-36 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Homo sapiens (Human) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 13465 FUN_013260 76 127 70 231 180 NA NA NA NA NA NA NA 13466 FUN_041342 0 47 51 40 29 NA NA NA NA NA NA NA 13467 FUN_041343 30 124 118 51 43 NA NA NA NA NA NA NA 13468 FUN_013264 4 0 0 89 29 NA NA NA NA NA NA NA 13469 FUN_041347 0 0 0 0 17 NA NA NA NA NA NA NA 13470 FUN_041348 98 112 200 19 133 NA NA NA NA NA NA NA 13471 FUN_041349 28 139 99 142 4 NA NA NA NA NA NA NA 13472 FUN_002258 0 0 0 0 8 NA NA NA NA NA NA NA 13473 FUN_002253 0 0 11 0 40 NA NA NA NA NA NA NA 13474 FUN_002250 0 0 0 6 10 ntLink_6:22885390-22890758 Q9J569 3.5e-22 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 13475 FUN_002257 9 0 0 2 41 NA NA NA NA NA NA NA 13476 FUN_002256 108 586 83 118 84 NA NA NA NA NA NA NA 13477 FUN_002254 65 0 32 0 85 ntLink_6:22897596-22900614 Q6LAF1 5.07e-47 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13478 FUN_013866 0 0 11 70 0 NA NA NA NA NA NA NA 13479 FUN_040088 32 23 0 80 64 ptg000031l:4032741-4035063 E7FAM5 7.39e-88 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 13480 FUN_040430 1 46 2 0 34 NA NA NA NA NA NA NA 13481 FUN_040433 34 5 45 3 144 NA NA NA NA NA NA NA 13482 FUN_040432 0 0 0 0 19 NA NA NA NA NA NA NA 13483 FUN_040435 200 134 151 91 35 NA NA NA NA NA NA NA 13484 FUN_040434 13 8 7 4 6 NA NA NA NA NA NA NA 13485 FUN_040437 419 1439 1424 443 280 NA NA NA NA NA NA NA 13486 FUN_040436 12 13 20 25 0 NA NA NA NA NA NA NA 13487 FUN_040439 372 808 782 590 376 NA NA NA NA NA NA NA 13488 FUN_040438 188 537 444 280 120 NA NA NA NA NA NA NA 13489 FUN_040089 1976 1358 781 2597 895 NA NA NA NA NA NA NA 13490 FUN_042491 35 1 54 3 281 NA NA NA NA NA NA NA 13491 FUN_042490 1 0 0 3 16 NA NA NA NA NA NA NA 13492 FUN_042493 34 4 41 3 234 NA NA NA NA NA NA NA 13493 FUN_042492 42 5 82 8 289 NA NA NA NA NA NA NA 13494 FUN_042495 0 0 0 12 0 NA NA NA NA NA NA NA 13495 FUN_042494 148 9 73 5 233 NA NA NA NA NA NA NA 13496 FUN_042496 4 0 5 0 12 ptg000037l:6342-8456 Q6LAF1 5.15e-45 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13497 FUN_042499 0 0 0 0 6 NA NA NA NA NA NA NA 13498 FUN_002929 12 13 7 6 1 NA NA NA NA NA NA NA 13499 FUN_002925 3 13 16 11 71 NA NA NA NA NA NA NA 13500 FUN_002927 0 0 14 0 21 NA NA NA NA NA NA NA 13501 FUN_002926 8 13 13 0 57 NA NA NA NA NA NA NA 13502 FUN_007913 352 179 188 193 151 NA NA NA NA NA NA NA 13503 FUN_018255 1885 918 1082 1787 1545 NA NA NA NA NA NA NA 13504 FUN_018256 72 233 6 39 90 NA NA NA NA NA NA NA 13505 FUN_007910 271 411 45 139 147 NA NA NA NA NA NA NA 13506 FUN_035478 7144 6363 3705 5543 5716 NA NA NA NA NA NA NA 13507 FUN_007917 20 38 0 0 37 NA NA NA NA NA NA NA 13508 FUN_007916 33 31 4 4 4 NA NA NA NA NA NA NA 13509 FUN_007915 315 130 57 54 98 NA NA NA NA NA NA NA 13510 FUN_029839 168 115 123 452 710 NA NA NA NA NA NA NA 13511 FUN_018253 153 57 31 936 242 NA NA NA NA NA NA NA 13512 FUN_035470 1123 988 781 1073 1127 NA NA NA NA NA NA NA 13513 FUN_032469 36 170 51 67 53 NA NA NA NA NA NA NA 13514 FUN_032468 11 37 37 15 15 NA NA NA NA NA NA NA 13515 FUN_032467 80 28 15 107 43 NA NA NA NA NA NA NA 13516 FUN_032466 62 91 17 118 68 ptg000023l:32259364-32266218 E9Q236 3.77e-77 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 13517 FUN_032466 62 91 17 118 68 ptg000023l:32259364-32266218 E9Q236 3.18e-54 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 13518 FUN_032466 62 91 17 118 68 ptg000023l:32259364-32266218 E9Q236 7.56e-33 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 13519 FUN_032465 81 89 53 220 92 NA NA NA NA NA NA NA 13520 FUN_032464 17 2 86 33 149 NA NA NA NA NA NA NA 13521 FUN_032463 0 0 0 0 13 NA NA NA NA NA NA NA 13522 FUN_032462 178 53 62 130 35 NA NA NA NA NA NA NA 13523 FUN_032461 821 288 421 632 508 ptg000023l:32162906-32207951 Q99315 1.19e-82 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 13524 FUN_032461 821 288 421 632 508 ptg000023l:32162906-32207951 Q99315 1.19e-82 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 13525 FUN_032460 5755 5773 3944 4248 3548 ptg000023l:32153538-32161081 Q5REI7 9.97e-22 Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ADP biosynthetic process [GO:0006172]; AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; phosphorylation [GO:0016310] GO:0004017; GO:0005524; GO:0005758; GO:0006172; GO:0016310; GO:0046033; GO:0046034; GO:0097226 13526 FUN_008448 1665 794 628 1471 797 NA NA NA NA NA NA NA 13527 FUN_008449 242 67 80 127 71 NA NA NA NA NA NA NA 13528 FUN_008444 1307 1310 853 1773 1505 ptg000002l:11626413-11627745 Q6IR75 0 COP9 signalosome complex subunit 2 (Signalosome subunit 2) Xenopus laevis (African clawed frog) NA GO:0005737; GO:0008180 13529 FUN_008445 246 67 68 130 169 ptg000002l:11632761-11634186 Q8BH16 1.72e-24 F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) Mus musculus (Mouse) modulation by host of viral RNA genome replication [GO:0044830]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of inflammatory response [GO:0050727]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005516; GO:0006511; GO:0006513; GO:0010506; GO:0014066; GO:0016020; GO:0016567; GO:0019005; GO:0019903; GO:0031146; GO:0036312; GO:0044830; GO:0050727; GO:1900226; GO:1990756 13530 FUN_008446 8791 9522 5345 8299 7501 ptg000002l:11637456-11645571 Q9VHS8 6.7e-31 Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; exon-exon junction complex assembly [GO:1903040]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of gene expression [GO:0010628]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0003724; GO:0003729; GO:0005524; GO:0005634; GO:0005730; GO:0006325; GO:0008380; GO:0010628; GO:0016887; GO:0045451; GO:0045495; GO:0051028; GO:0071011; GO:0071013; GO:1903040 13531 FUN_008446 8791 9522 5345 8299 7501 ptg000002l:11637456-11645571 Q9VHS8 6.7e-31 Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; exon-exon junction complex assembly [GO:1903040]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of gene expression [GO:0010628]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0003724; GO:0003729; GO:0005524; GO:0005634; GO:0005730; GO:0006325; GO:0008380; GO:0010628; GO:0016887; GO:0045451; GO:0045495; GO:0051028; GO:0071011; GO:0071013; GO:1903040 13532 FUN_008446 8791 9522 5345 8299 7501 ptg000002l:11637456-11645571 Q9VHS8 5.7e-21 Eukaryotic initiation factor 4A-III (eIF-4A-III) (eIF4A-III) (EC 3.6.4.13) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; exon-exon junction complex assembly [GO:1903040]; mRNA splicing, via spliceosome [GO:0000398]; mRNA transport [GO:0051028]; pole plasm oskar mRNA localization [GO:0045451]; positive regulation of gene expression [GO:0010628]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0003724; GO:0003729; GO:0005524; GO:0005634; GO:0005730; GO:0006325; GO:0008380; GO:0010628; GO:0016887; GO:0045451; GO:0045495; GO:0051028; GO:0071011; GO:0071013; GO:1903040 13533 FUN_008447 3273 3738 1382 2629 2688 NA NA NA NA NA NA NA 13534 FUN_008440 485 567 323 786 630 ptg000002l:11589731-11596722 O08759 1.76e-31 Ubiquitin-protein ligase E3A (EC 2.3.2.26) (HECT-type ubiquitin transferase E3A) (Oncogenic protein-associated protein E6-AP) Mus musculus (Mouse) androgen receptor signaling pathway [GO:0030521]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; locomotory exploration behavior [GO:0035641]; modulation of chemical synaptic transmission [GO:0050804]; motor learning [GO:0061743]; negative regulation of dendritic spine morphogenesis [GO:0061002]; ovarian follicle development [GO:0001541]; positive regulation of Golgi lumen acidification [GO:1905528]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to cocaine [GO:0042220]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; rhythmic process [GO:0048511]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000502; GO:0001541; GO:0003713; GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0014068; GO:0016567; GO:0030521; GO:0031398; GO:0032570; GO:0035037; GO:0035641; GO:0042220; GO:0042542; GO:0042752; GO:0045944; GO:0046872; GO:0048511; GO:0050804; GO:0050847; GO:0051865; GO:0060736; GO:0061002; GO:0061630; GO:0061743; GO:0070936; GO:0098978; GO:1905528; GO:1990416; GO:2000058 13535 FUN_008441 2284 2366 1997 2308 1584 NA NA NA NA NA NA NA 13536 FUN_008442 168 111 140 205 112 ptg000002l:11603437-11609397 Q29RQ5 5.39e-51 E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005737; GO:0005856; GO:0008021; GO:0008270; GO:0030425; GO:0043161; GO:0061630 13537 FUN_008442 168 111 140 205 112 ptg000002l:11603437-11609397 Q29RQ5 3.65e-46 E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0005737; GO:0005856; GO:0008021; GO:0008270; GO:0030425; GO:0043161; GO:0061630 13538 FUN_008443 22 76 30 40 72 NA NA NA NA NA NA NA 13539 FUN_000273 443 121 29 25 8 NA NA NA NA NA NA NA 13540 FUN_000272 20 0 5 0 113 NA NA NA NA NA NA NA 13541 FUN_000271 7063 6239 3743 8883 5182 NA NA NA NA NA NA NA 13542 FUN_000277 1830 380 443 976 891 NA NA NA NA NA NA NA 13543 FUN_000276 1270 1401 946 1129 672 NA NA NA NA NA NA NA 13544 FUN_000275 1755 2154 1239 1519 803 NA NA NA NA NA NA NA 13545 FUN_000274 0 0 40 48 69 NA NA NA NA NA NA NA 13546 FUN_000279 73 161 70 39 90 NA NA NA NA NA NA NA 13547 FUN_000278 0 14 28 0 0 NA NA NA NA NA NA NA 13548 FUN_042248 0 0 3 1 7 NA NA NA NA NA NA NA 13549 FUN_000588 2786 2502 1462 3651 2421 ntLink_6:4739575-4750644 Q25214 1.5e-31 Protein scalloped Junonia coenia (Peacock butterfly) (Precis coenia) NA GO:0003677; GO:0005634; GO:0046872 13550 FUN_029166 17056 15116 8583 12844 7891 ptg000022l:8889965-8900991 Q8HXX7 1.17e-24 Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) negative regulation of axonogenesis [GO:0050771]; negative regulation of protein targeting to membrane [GO:0090315]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482] GO:0005093; GO:0005096; GO:0005794; GO:0015031; GO:0032482; GO:0050771; GO:0090315 13551 FUN_029167 724 351 340 398 390 NA NA NA NA NA NA NA 13552 FUN_029164 4 0 2 2 25 NA NA NA NA NA NA NA 13553 FUN_029165 1121 356 477 1003 443 ptg000022l:8880018-8883529 Q91035 2.38e-37 Sonic hedgehog protein (SHH) (EC 3.1.-.-) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp)] Gallus gallus (Chicken) anterior/posterior pattern specification [GO:0009952]; apoptotic signaling pathway [GO:0097190]; cell fate determination [GO:0001709]; cell fate specification involved in pattern specification [GO:0060573]; cell-cell signaling [GO:0007267]; chondroblast differentiation [GO:0060591]; commissural neuron axon guidance [GO:0071679]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; fibroblast growth factor production [GO:0090269]; floor plate formation [GO:0021508]; growth plate cartilage chondrocyte growth [GO:0003430]; homeostasis of number of retina cells [GO:0048877]; intein-mediated protein splicing [GO:0016539]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; optic cup formation involved in camera-type eye development [GO:0003408]; optic nerve morphogenesis [GO:0021631]; polarity specification of anterior/posterior axis [GO:0009949]; polarity specification of dorsal/ventral axis [GO:0009951]; positive regulation of alkaline phosphatase activity [GO:0010694]; positive regulation of cell morphogenesis involved in differentiation [GO:0010770]; positive regulation of gene expression [GO:0010628]; positive regulation of neural retina development [GO:0061075]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; proteoglycan biosynthetic process [GO:0030166]; regulation of apoptosis involved in tissue homeostasis [GO:0060785]; regulation of cell differentiation involved in tissue homeostasis [GO:0060786]; regulation of gene expression [GO:0010468]; regulation of neural precursor cell proliferation [GO:2000177]; response to retinoic acid [GO:0032526]; retina homeostasis [GO:0001895]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; signaling [GO:0023052]; spinal cord dorsal/ventral patterning [GO:0021513]; tissue development [GO:0009888] GO:0000139; GO:0001709; GO:0001895; GO:0003406; GO:0003408; GO:0003430; GO:0005509; GO:0005576; GO:0005615; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0007267; GO:0008233; GO:0008270; GO:0009880; GO:0009888; GO:0009949; GO:0009951; GO:0009952; GO:0010468; GO:0010628; GO:0010694; GO:0010770; GO:0016015; GO:0016539; GO:0016540; GO:0021508; GO:0021513; GO:0021631; GO:0023052; GO:0030166; GO:0030326; GO:0030514; GO:0032526; GO:0042733; GO:0043066; GO:0045669; GO:0045880; GO:0048877; GO:0060059; GO:0060573; GO:0060591; GO:0060785; GO:0060786; GO:0061075; GO:0071679; GO:0090269; GO:0097190; GO:0097264; GO:0140853; GO:2000177 13554 FUN_029163 0 0 0 33 0 NA NA NA NA NA NA NA 13555 FUN_029160 3 0 0 0 14 NA NA NA NA NA NA NA 13556 FUN_029161 47 27 0 9 82 NA NA NA NA NA NA NA 13557 FUN_029168 552 455 294 424 443 NA NA NA NA NA NA NA 13558 FUN_029169 2115 1473 699 1371 1235 NA NA NA NA NA NA NA 13559 FUN_033738 2825 1961 1392 2082 1521 NA NA NA NA NA NA NA 13560 FUN_033739 0 49 13 44 37 NA NA NA NA NA NA NA 13561 FUN_033734 1902 2918 1227 7239 9864 NA NA NA NA NA NA NA 13562 FUN_033735 327 129 246 327 351 NA NA NA NA NA NA NA 13563 FUN_033736 2504 4632 1169 2091 1417 NA NA NA NA NA NA NA 13564 FUN_033730 992 212 397 450 751 NA NA NA NA NA NA NA 13565 FUN_033731 166 144 138 164 219 ptg000024l:760374-761744 Q6PHG8 3.59e-33 DNA-directed RNA polymerase I subunit RPA43 (DNA-directed RNA polymerase I subunit F) (Twist neighbor protein) Danio rerio (Zebrafish) (Brachydanio rerio) DNA-templated transcription initiation [GO:0006352] GO:0005736; GO:0006352 13566 FUN_033732 707 312 304 850 438 ptg000024l:765599-768973 B3EWY8 2.37e-68 Skeletal aspartic acid-rich protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13567 FUN_033732 707 312 304 850 438 ptg000024l:765599-768973 B3EWY8 2.79e-44 Skeletal aspartic acid-rich protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13568 FUN_033732 707 312 304 850 438 ptg000024l:765599-768973 B3EWY8 3.47e-31 Skeletal aspartic acid-rich protein 2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 13569 FUN_033733 1918 2922 1598 7772 9028 NA NA NA NA NA NA NA 13570 FUN_025797 336 2274 3872 6058 1934 NA NA NA NA NA NA NA 13571 FUN_017638 38 0 0 0 190 NA NA NA NA NA NA NA 13572 FUN_014825 0 0 6 0 86 NA NA NA NA NA NA NA 13573 FUN_040394 39 46 15 2 0 NA NA NA NA NA NA NA 13574 FUN_040395 60 26 45 7 99 NA NA NA NA NA NA NA 13575 FUN_040396 445 302 295 383 276 ptg000031l:7802002-7807320 Q6L8S8 3.72e-27 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 13576 FUN_040390 15 31 5 54 35 NA NA NA NA NA NA NA 13577 FUN_040391 15 0 0 0 0 NA NA NA NA NA NA NA 13578 FUN_015994 4079 4212 2820 3320 1962 NA NA NA NA NA NA NA 13579 FUN_010747 89 60 39 259 295 ptg000007l:2331486-2332887 Q8IYB1 1.32e-21 Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2) Homo sapiens (Human) NA GO:0016779; GO:0044877; GO:0045296 13580 FUN_010744 0 0 1 40 11 NA NA NA NA NA NA NA 13581 FUN_015997 868 741 467 1112 654 NA NA NA NA NA NA NA 13582 FUN_010742 8380 6950 3501 5860 4322 NA NA NA NA NA NA NA 13583 FUN_010743 36 15 0 11 71 NA NA NA NA NA NA NA 13584 FUN_010740 1242 818 423 996 746 NA NA NA NA NA NA NA 13585 FUN_010741 61 34 21 40 35 NA NA NA NA NA NA NA 13586 FUN_015998 3453 2357 1763 3197 3217 ptg000010l:295597-317704 Q91738 4.6e-27 Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Protein-tyrosine kinase 2) (pp125FAK) Xenopus laevis (African clawed frog) positive regulation of cell population proliferation [GO:0008284]; regulation of cellular component organization [GO:0051128]; response to stimulus [GO:0050896]; signal complex assembly [GO:0007172] GO:0004715; GO:0005524; GO:0005737; GO:0005886; GO:0005925; GO:0007172; GO:0008284; GO:0036064; GO:0050896; GO:0051128 13587 FUN_015999 128 83 42 105 75 NA NA NA NA NA NA NA 13588 FUN_010748 1630 219 35 1032 246 NA NA NA NA NA NA NA 13589 FUN_010749 991 149 7 646 187 NA NA NA NA NA NA NA 13590 FUN_012678 3244 2877 1817 2123 1267 ptg000008l:11265895-11269299 O22943 1.94e-70 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 13591 FUN_012679 2253 4327 1927 1298 681 ptg000008l:11276734-11279245 O22943 1.12e-71 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 13592 FUN_012670 16175 20728 10311 16875 10328 NA NA NA NA NA NA NA 13593 FUN_017287 19 0 0 0 0 NA NA NA NA NA NA NA 13594 FUN_012672 1777 2139 1428 2320 1795 ptg000008l:11174396-11174768 Q9CY97 2.16e-27 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (CTD phosphatase SSU72) (EC 3.1.3.16) Mus musculus (Mouse) dephosphorylation of RNA polymerase II C-terminal domain [GO:0070940]; mRNA polyadenylation [GO:0006378]; termination of RNA polymerase II transcription [GO:0006369] GO:0005654; GO:0005829; GO:0005847; GO:0006369; GO:0006378; GO:0008420; GO:0017018; GO:0070940 13595 FUN_017285 0 0 0 0 11 NA NA NA NA NA NA NA 13596 FUN_017282 0 0 0 0 35 NA NA NA NA NA NA NA 13597 FUN_012675 59802 84960 61218 66086 40450 NA NA NA NA NA NA NA 13598 FUN_017280 0 9 15 6 0 NA NA NA NA NA NA NA 13599 FUN_012677 1592 1836 871 1518 1385 NA NA NA NA NA NA NA 13600 FUN_038920 791 349 398 328 389 ptg000027l:12851955-12855261 A4IH75 2.97e-95 Autophagy-related protein 101 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagy [GO:0006914] GO:0000407; GO:0006914 13601 FUN_038921 3672 5535 2048 2942 1997 NA NA NA NA NA NA NA 13602 FUN_038923 0 11 0 0 0 NA NA NA NA NA NA NA 13603 FUN_038925 0 6 0 0 0 NA NA NA NA NA NA NA 13604 FUN_038926 7 2 9 1 1 NA NA NA NA NA NA NA 13605 FUN_038927 389 297 175 330 261 ptg000027l:12958266-12964000 P56213 3.81e-21 FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) Mus musculus (Mouse) cellular response to actinomycin D [GO:0072717]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to toxic substance [GO:0097237]; cellular response to tumor necrosis factor [GO:0071356]; liver development [GO:0001889]; liver regeneration [GO:0097421]; negative regulation of apoptotic process [GO:0043066]; negative regulation of natural killer cell mediated cytotoxicity [GO:0045953]; negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of DNA biosynthetic process [GO:2000573] GO:0001889; GO:0005615; GO:0005739; GO:0005758; GO:0005829; GO:0008083; GO:0015035; GO:0016971; GO:0043066; GO:0045953; GO:0050660; GO:0071222; GO:0071356; GO:0072717; GO:0097237; GO:0097421; GO:1903204; GO:2000573 13606 FUN_038928 61 0 0 2 0 NA NA NA NA NA NA NA 13607 FUN_038929 0 0 0 11 0 NA NA NA NA NA NA NA 13608 FUN_006470 73 111 55 0 11 NA NA NA NA NA NA NA 13609 FUN_014485 700 441 232 678 366 NA NA NA NA NA NA NA 13610 FUN_014484 254 256 76 119 159 ptg000009l:586472-589028 Q9SR22 2.72e-65 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 13611 FUN_014487 5734 5010 2991 4727 5809 ptg000009l:605577-608371 Q9D4H7 3.28e-57 LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127) Mus musculus (Mouse) NA GO:0005737; GO:0046872; GO:0061630 13612 FUN_014487 5734 5010 2991 4727 5809 ptg000009l:605577-608371 Q9D4H7 3.85e-31 LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127) Mus musculus (Mouse) NA GO:0005737; GO:0046872; GO:0061630 13613 FUN_014486 3115 2250 2177 3150 2845 ptg000009l:595222-601967 O09106 8.47e-32 Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) Mus musculus (Mouse) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; hippocampus development [GO:0021766]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell fate specification [GO:0042659]; regulation of endopeptidase activity [GO:0052548]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000122; GO:0000785; GO:0000792; GO:0000976; GO:0000978; GO:0000979; GO:0001046; GO:0001222; GO:0002039; GO:0003677; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006325; GO:0006338; GO:0006346; GO:0006357; GO:0006476; GO:0007492; GO:0007623; GO:0008284; GO:0009913; GO:0010629; GO:0016575; GO:0016580; GO:0016581; GO:0017053; GO:0019213; GO:0019899; GO:0021766; GO:0030182; GO:0030336; GO:0030512; GO:0032922; GO:0032991; GO:0033558; GO:0035851; GO:0042475; GO:0042659; GO:0042733; GO:0042826; GO:0043005; GO:0043025; GO:0043066; GO:0043124; GO:0043922; GO:0044877; GO:0045892; GO:0045893; GO:0045944; GO:0047485; GO:0048471; GO:0048709; GO:0048714; GO:0051059; GO:0052548; GO:0060766; GO:0060789; GO:0061029; GO:0061198; GO:0061629; GO:0070888; GO:0070932; GO:0070933; GO:0090090; GO:0140297; GO:0160009; GO:1902455; GO:1902459; GO:1990841; GO:2000273; GO:2000736; GO:2001243 13614 FUN_014486 3115 2250 2177 3150 2845 ptg000009l:595222-601967 O09106 8.47e-32 Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) Mus musculus (Mouse) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; hippocampus development [GO:0021766]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell fate specification [GO:0042659]; regulation of endopeptidase activity [GO:0052548]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000122; GO:0000785; GO:0000792; GO:0000976; GO:0000978; GO:0000979; GO:0001046; GO:0001222; GO:0002039; GO:0003677; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006325; GO:0006338; GO:0006346; GO:0006357; GO:0006476; GO:0007492; GO:0007623; GO:0008284; GO:0009913; GO:0010629; GO:0016575; GO:0016580; GO:0016581; GO:0017053; GO:0019213; GO:0019899; GO:0021766; GO:0030182; GO:0030336; GO:0030512; GO:0032922; GO:0032991; GO:0033558; GO:0035851; GO:0042475; GO:0042659; GO:0042733; GO:0042826; GO:0043005; GO:0043025; GO:0043066; GO:0043124; GO:0043922; GO:0044877; GO:0045892; GO:0045893; GO:0045944; GO:0047485; GO:0048471; GO:0048709; GO:0048714; GO:0051059; GO:0052548; GO:0060766; GO:0060789; GO:0061029; GO:0061198; GO:0061629; GO:0070888; GO:0070932; GO:0070933; GO:0090090; GO:0140297; GO:0160009; GO:1902455; GO:1902459; GO:1990841; GO:2000273; GO:2000736; GO:2001243 13615 FUN_014486 3115 2250 2177 3150 2845 ptg000009l:595222-601967 O09106 1.21e-21 Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-) Mus musculus (Mouse) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; circadian rhythm [GO:0007623]; DNA methylation-dependent heterochromatin formation [GO:0006346]; embryonic digit morphogenesis [GO:0042733]; endoderm development [GO:0007492]; epidermal cell differentiation [GO:0009913]; eyelid development in camera-type eye [GO:0061029]; fungiform papilla formation [GO:0061198]; hair follicle placode formation [GO:0060789]; hippocampus development [GO:0021766]; histone deacetylation [GO:0016575]; histone H3 deacetylation [GO:0070932]; histone H4 deacetylation [GO:0070933]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of androgen receptor signaling pathway [GO:0060766]; negative regulation of apoptotic process [GO:0043066]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell migration [GO:0030336]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of stem cell population maintenance [GO:1902455]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; odontogenesis of dentin-containing tooth [GO:0042475]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein deacetylation [GO:0006476]; regulation of cell fate specification [GO:0042659]; regulation of endopeptidase activity [GO:0052548]; regulation of stem cell differentiation [GO:2000736]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000118; GO:0000122; GO:0000785; GO:0000792; GO:0000976; GO:0000978; GO:0000979; GO:0001046; GO:0001222; GO:0002039; GO:0003677; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005829; GO:0006325; GO:0006338; GO:0006346; GO:0006357; GO:0006476; GO:0007492; GO:0007623; GO:0008284; GO:0009913; GO:0010629; GO:0016575; GO:0016580; GO:0016581; GO:0017053; GO:0019213; GO:0019899; GO:0021766; GO:0030182; GO:0030336; GO:0030512; GO:0032922; GO:0032991; GO:0033558; GO:0035851; GO:0042475; GO:0042659; GO:0042733; GO:0042826; GO:0043005; GO:0043025; GO:0043066; GO:0043124; GO:0043922; GO:0044877; GO:0045892; GO:0045893; GO:0045944; GO:0047485; GO:0048471; GO:0048709; GO:0048714; GO:0051059; GO:0052548; GO:0060766; GO:0060789; GO:0061029; GO:0061198; GO:0061629; GO:0070888; GO:0070932; GO:0070933; GO:0090090; GO:0140297; GO:0160009; GO:1902455; GO:1902459; GO:1990841; GO:2000273; GO:2000736; GO:2001243 13616 FUN_014481 2153 2804 1146 2045 1349 NA NA NA NA NA NA NA 13617 FUN_014480 54928 68094 55296 63168 43197 NA NA NA NA NA NA NA 13618 FUN_014483 1709 1061 750 1896 1302 ptg000009l:577309-584457 Q5HZM6 2.15e-37 Elongator complex protein 3 (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) Xenopus laevis (African clawed frog) negative regulation of protein ubiquitination [GO:0031397]; neural crest cell migration [GO:0001755]; protein stabilization [GO:0050821]; regulation of transcription by RNA polymerase II [GO:0006357]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0001755; GO:0002098; GO:0005634; GO:0005737; GO:0006357; GO:0008607; GO:0031397; GO:0046872; GO:0050821; GO:0051539; GO:0106261 13619 FUN_014483 1709 1061 750 1896 1302 ptg000009l:577309-584457 Q5HZM6 2.15e-37 Elongator complex protein 3 (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) Xenopus laevis (African clawed frog) negative regulation of protein ubiquitination [GO:0031397]; neural crest cell migration [GO:0001755]; protein stabilization [GO:0050821]; regulation of transcription by RNA polymerase II [GO:0006357]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0001755; GO:0002098; GO:0005634; GO:0005737; GO:0006357; GO:0008607; GO:0031397; GO:0046872; GO:0050821; GO:0051539; GO:0106261 13620 FUN_014482 13 21 0 17 47 NA NA NA NA NA NA NA 13621 FUN_014489 1637 1808 869 1333 797 NA NA NA NA NA NA NA 13622 FUN_014488 4756 3290 2469 3999 3561 NA NA NA NA NA NA NA 13623 FUN_006275 4385 2183 2519 3777 4099 NA NA NA NA NA NA NA 13624 FUN_013109 0 0 27 0 0 NA NA NA NA NA NA NA 13625 FUN_014739 1226 1082 787 1476 2000 NA NA NA NA NA NA NA 13626 FUN_014738 3028 1797 1722 2095 2762 ptg000009l:2614651-2627196 A1A5R8 2.42e-22 SANT and BTB domain regulator of class switch recombination (SANT and BTB domain regulator of CSR) Rattus norvegicus (Rat) isotype switching [GO:0045190] GO:0042802; GO:0045190 13627 FUN_013101 0 0 13 0 0 NA NA NA NA NA NA NA 13628 FUN_013100 0 8 30 0 0 ptg000008l:19588574-19589866 Q8C8H8 3.62e-21 Kyphoscoliosis peptidase (EC 3.4.-.-) Mus musculus (Mouse) muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; proteolysis [GO:0006508] GO:0005737; GO:0005856; GO:0006508; GO:0007517; GO:0007528; GO:0008233; GO:0030018 13629 FUN_014735 2809 2290 1502 2552 2073 NA NA NA NA NA NA NA 13630 FUN_014733 1666 1474 1024 1612 1161 NA NA NA NA NA NA NA 13631 FUN_014731 864 654 442 621 676 NA NA NA NA NA NA NA 13632 FUN_014730 3163 2541 1461 2279 1769 NA NA NA NA NA NA NA 13633 FUN_005090 297 1046 656 2542 290 ntLink_8:30954464-30978183 P08548 2.81e-95 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 13634 FUN_009278 115 63 113 85 196 NA NA NA NA NA NA NA 13635 FUN_009279 302 118 100 52 85 NA NA NA NA NA NA NA 13636 FUN_009270 1721 969 1023 1212 1502 NA NA NA NA NA NA NA 13637 FUN_009271 1416 449 488 1315 802 NA NA NA NA NA NA NA 13638 FUN_009272 28 9 0 22 28 NA NA NA NA NA NA NA 13639 FUN_009273 41 42 22 20 85 NA NA NA NA NA NA NA 13640 FUN_009274 201 129 23 113 197 ptg000004l:4766959-4772362 Q96AY4 1.15e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13641 FUN_009274 201 129 23 113 197 ptg000004l:4766959-4772362 Q96AY4 1.41e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13642 FUN_009274 201 129 23 113 197 ptg000004l:4766959-4772362 Q96AY4 2.65e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13643 FUN_009274 201 129 23 113 197 ptg000004l:4766959-4772362 Q96AY4 1.13e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13644 FUN_009274 201 129 23 113 197 ptg000004l:4766959-4772362 Q96AY4 2.04e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13645 FUN_009274 201 129 23 113 197 ptg000004l:4766959-4772362 Q96AY4 1.41e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13646 FUN_009275 1754 46 374 2655 615 NA NA NA NA NA NA NA 13647 FUN_009276 2030 2201 1164 1301 842 NA NA NA NA NA NA NA 13648 FUN_009277 0 34 27 290 173 NA NA NA NA NA NA NA 13649 FUN_025247 0 24 0 0 3 NA NA NA NA NA NA NA 13650 FUN_022213 306 144 159 150 161 NA NA NA NA NA NA NA 13651 FUN_026668 1153 1052 4 6 0 ptg000020l:12146233-12150787 C5NSL2 1.2e-24 DELTA-actitoxin-Aas1a (DELTA-AITX-Aas1a) (Bandaporin) (Cytolysin bp-1) Anthopleura asiatica (Sea anemone) cation transport [GO:0006812]; cytolysis in another organism [GO:0051715]; pore complex assembly [GO:0046931] GO:0005576; GO:0006812; GO:0015267; GO:0042151; GO:0044218; GO:0046930; GO:0046931; GO:0051715; GO:0090729 13652 FUN_026669 18 45 55 39 152 NA NA NA NA NA NA NA 13653 FUN_025244 28 0 0 0 0 NA NA NA NA NA NA NA 13654 FUN_022215 40 45 33 123 105 NA NA NA NA NA NA NA 13655 FUN_026667 28 21 0 0 0 NA NA NA NA NA NA NA 13656 FUN_015468 336 76 142 122 221 NA NA NA NA NA NA NA 13657 FUN_015469 577 529 132 496 129 NA NA NA NA NA NA NA 13658 FUN_015464 35 17 9 38 3 NA NA NA NA NA NA NA 13659 FUN_015465 317 381 228 360 159 NA NA NA NA NA NA NA 13660 FUN_015466 732 618 293 991 582 ptg000009l:10532196-10535367 Q09143 3.37e-103 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor) (Ecotropic retrovirus receptor) (ERR) (EcoR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Mus musculus (Mouse) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; regulation of TOR signaling [GO:0032006] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032006; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:1903352; GO:1903810; GO:1903826 13661 FUN_015467 1225 582 424 952 574 NA NA NA NA NA NA NA 13662 FUN_015460 102 43 35 11 33 ptg000009l:10451008-10452187 Q5ZM55 2.69e-84 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Gallus gallus (Chicken) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 13663 FUN_015461 1591 368 1134 482 1536 ptg000009l:10458722-10489114 Q6GPE5 1.97e-126 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 13664 FUN_015461 1591 368 1134 482 1536 ptg000009l:10458722-10489114 Q6GPE5 1.64e-100 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 13665 FUN_015461 1591 368 1134 482 1536 ptg000009l:10458722-10489114 Q6GPE5 3.71e-44 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 13666 FUN_015462 182 85 92 132 140 NA NA NA NA NA NA NA 13667 FUN_015463 608 818 122 1629 91 ptg000009l:10519146-10522881 Q96CG8 3.68e-29 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 13668 FUN_018739 0 139 0 184 48 NA NA NA NA NA NA NA 13669 FUN_018738 86 108 55 46 76 NA NA NA NA NA NA NA 13670 FUN_018733 0 0 0 66 0 NA NA NA NA NA NA NA 13671 FUN_018737 4 16 0 31 34 NA NA NA NA NA NA NA 13672 FUN_018736 0 0 0 0 124 ptg000012l:12660059-12689760 P10978 1.7e-48 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 13673 FUN_018735 0 0 0 0 37 ptg000012l:12643049-12658327 P10394 3.26e-76 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 13674 FUN_018735 0 0 0 0 37 ptg000012l:12643049-12658327 P10394 3.26e-76 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 13675 FUN_018734 0 0 0 0 26 NA NA NA NA NA NA NA 13676 FUN_017905 64 64 41 46 62 NA NA NA NA NA NA NA 13677 FUN_017904 31 48 21 36 27 NA NA NA NA NA NA NA 13678 FUN_017907 53 66 38 46 55 NA NA NA NA NA NA NA 13679 FUN_017901 1432 516 619 1179 686 ptg000012l:1715563-1721516 Q1HKZ5 8.53e-24 Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) Mus musculus (Mouse) JNK cascade [GO:0007254]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon extension [GO:0045773]; positive regulation of branching morphogenesis of a nerve [GO:1905492]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase activity [GO:0045860]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403] GO:0004674; GO:0004706; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0007254; GO:0014042; GO:0016020; GO:0018105; GO:0019899; GO:0042802; GO:0042803; GO:0043507; GO:0043539; GO:0045773; GO:0045860; GO:0046777; GO:0046872; GO:0051092; GO:0051403; GO:0106137; GO:0106310; GO:0150012; GO:1905492 13680 FUN_017901 1432 516 619 1179 686 ptg000012l:1715563-1721516 Q1HKZ5 5.46e-22 Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) Mus musculus (Mouse) JNK cascade [GO:0007254]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of axon extension [GO:0045773]; positive regulation of branching morphogenesis of a nerve [GO:1905492]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection arborization [GO:0150012]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein kinase activity [GO:0045860]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; stress-activated MAPK cascade [GO:0051403] GO:0004674; GO:0004706; GO:0004709; GO:0005524; GO:0005737; GO:0006468; GO:0007254; GO:0014042; GO:0016020; GO:0018105; GO:0019899; GO:0042802; GO:0042803; GO:0043507; GO:0043539; GO:0045773; GO:0045860; GO:0046777; GO:0046872; GO:0051092; GO:0051403; GO:0106137; GO:0106310; GO:0150012; GO:1905492 13681 FUN_017900 3409 3585 1620 3388 2407 NA NA NA NA NA NA NA 13682 FUN_017903 25 8 0 10 80 NA NA NA NA NA NA NA 13683 FUN_017902 273 54 81 168 235 NA NA NA NA NA NA NA 13684 FUN_017909 100 108 68 90 87 NA NA NA NA NA NA NA 13685 FUN_017908 61 79 45 61 85 NA NA NA NA NA NA NA 13686 FUN_025319 6502 3179 2440 3482 2954 ptg000019l:1230353-1232020 P67963 0 Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; intermediate filament cytoskeleton organization [GO:0045104]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0000776; GO:0004674; GO:0005524; GO:0005737; GO:0005819; GO:0006468; GO:0007049; GO:0016055; GO:0016607; GO:0036064; GO:0045104; GO:0051301; GO:0106310; GO:1900226 13687 FUN_025318 122 104 57 131 71 NA NA NA NA NA NA NA 13688 FUN_025311 145 151 98 226 125 NA NA NA NA NA NA NA 13689 FUN_025310 100 111 169 165 172 NA NA NA NA NA NA NA 13690 FUN_025313 13 27 0 0 15 NA NA NA NA NA NA NA 13691 FUN_025312 40 10 9 4 107 NA NA NA NA NA NA NA 13692 FUN_025315 1066 726 486 902 1854 NA NA NA NA NA NA NA 13693 FUN_025314 1786 728 661 1201 931 NA NA NA NA NA NA NA 13694 FUN_025317 304 71 166 142 243 NA NA NA NA NA NA NA 13695 FUN_025316 77 4 29 138 26 NA NA NA NA NA NA NA 13696 FUN_006277 4306 1689 1577 2655 1159 ptg000001l:10082453-10083972 P14207 2.28e-46 Folate receptor beta (FR-beta) (Folate receptor 2) (Folate receptor, fetal/placental) (Placental folate-binding protein) (FBP) Homo sapiens (Human) cell adhesion [GO:0007155]; folic acid transport [GO:0015884]; fusion of sperm to egg plasma membrane involved in single fertilization [GO:0007342]; inflammatory response [GO:0006954]; positive regulation of cell population proliferation [GO:0008284]; sperm-egg recognition [GO:0035036] GO:0005542; GO:0005576; GO:0005886; GO:0006954; GO:0007155; GO:0007342; GO:0008284; GO:0009897; GO:0009986; GO:0015884; GO:0035036; GO:0038023; GO:0061714 13697 FUN_036251 4855 4927 3205 6992 6851 ptg000025l:17150778-17158438 P41035 5.35e-21 Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta) Oryctolagus cuniculus (Rabbit) in utero embryonic development [GO:0001701]; male germ cell proliferation [GO:0002176]; male gonad development [GO:0008584] GO:0001701; GO:0002176; GO:0003743; GO:0005850; GO:0008584; GO:0045202; GO:0046872 13698 FUN_044371 10 0 0 0 8 NA NA NA NA NA NA NA 13699 FUN_001814 9 0 0 43 31 NA NA NA NA NA NA NA 13700 FUN_001815 0 0 0 16 10 NA NA NA NA NA NA NA 13701 FUN_001817 846 499 287 529 628 NA NA NA NA NA NA NA 13702 FUN_001812 1158 1903 561 1382 813 NA NA NA NA NA NA NA 13703 FUN_001813 0 0 0 56 0 NA NA NA NA NA NA NA 13704 FUN_020095 30 0 47 25 176 NA NA NA NA NA NA NA 13705 FUN_020094 24 0 0 0 179 NA NA NA NA NA NA NA 13706 FUN_020093 0 0 0 0 7 NA NA NA NA NA NA NA 13707 FUN_035549 2026 2010 1303 1413 675 NA NA NA NA NA NA NA 13708 FUN_035548 14 26 0 24 14 NA NA NA NA NA NA NA 13709 FUN_030719 0 0 0 0 6 NA NA NA NA NA NA NA 13710 FUN_030717 273 51 6 227 101 NA NA NA NA NA NA NA 13711 FUN_030716 1830 1580 730 579 296 NA NA NA NA NA NA NA 13712 FUN_035547 161 86 76 262 61 NA NA NA NA NA NA NA 13713 FUN_035541 2647 1260 1517 2532 777 NA NA NA NA NA NA NA 13714 FUN_035543 1315 768 1191 2138 1103 NA NA NA NA NA NA NA 13715 FUN_030710 17 2 17 2 11 NA NA NA NA NA NA NA 13716 FUN_036012 13 22 0 12 16 NA NA NA NA NA NA NA 13717 FUN_036013 48 0 65 0 17 ptg000025l:14485383-14488177 Q9QZ85 8.64e-27 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 13718 FUN_036010 0 22 114 0 0 ptg000025l:14444915-14451009 Q9QZ85 1.6e-37 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 13719 FUN_036011 25 16 3217 3949 2771 ptg000025l:14457655-14480075 Q6NXR0 4.95e-30 Interferon-inducible GTPase 5 (EC 3.6.5.-) (Immunity-related GTPase cinema 1) Homo sapiens (Human) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952] GO:0003924; GO:0005525; GO:0005789; GO:0006952; GO:0035458 13720 FUN_036016 394 254 187 326 253 ptg000025l:14528598-14532140 Q9BYG0 1.74e-32 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) Homo sapiens (Human) brain development [GO:0007420]; central nervous system development [GO:0007417]; glycolipid biosynthetic process [GO:0009247]; O-glycan processing [GO:0016266]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0007417; GO:0007420; GO:0008457; GO:0008499; GO:0009247; GO:0016266; GO:0016757; GO:0047256 13721 FUN_036014 0 12 0 0 0 NA NA NA NA NA NA NA 13722 FUN_036015 538 429 474 431 343 ptg000025l:14492540-14521754 Q9QZ85 1.86e-35 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 13723 FUN_031044 0 0 0 49 0 NA NA NA NA NA NA NA 13724 FUN_031045 0 0 27 0 0 NA NA NA NA NA NA NA 13725 FUN_036018 3260 2200 1234 3126 2380 NA NA NA NA NA NA NA 13726 FUN_036019 456 562 272 343 479 ptg000025l:14555137-14557207 Q5R8P3 1.54e-33 Bardet-Biedl syndrome 10 protein homolog Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) chaperone-mediated protein complex assembly [GO:0051131] GO:0005524; GO:0005929; GO:0051131 13727 FUN_031040 1 0 13 4 38 NA NA NA NA NA NA NA 13728 FUN_031042 0 0 0 9 30 NA NA NA NA NA NA NA 13729 FUN_031043 20 2 62 3 65 NA NA NA NA NA NA NA 13730 FUN_039670 0 0 0 0 39 NA NA NA NA NA NA NA 13731 FUN_039679 0 0 0 0 12 NA NA NA NA NA NA NA 13732 FUN_007311 0 0 0 0 9 NA NA NA NA NA NA NA 13733 FUN_037945 593 937 632 1233 306 NA NA NA NA NA NA NA 13734 FUN_037944 10880 10242 6839 7488 3306 ptg000027l:730675-731652 A4F4L4 9.53e-27 Dynein axonemal light chain 4 Sus scrofa (Pig) microtubule-based process [GO:0007017] GO:0005737; GO:0005874; GO:0005929; GO:0007017; GO:0030286; GO:0042802 13735 FUN_037943 1912 1771 1272 1540 1286 NA NA NA NA NA NA NA 13736 FUN_037942 253 451 512 369 844 NA NA NA NA NA NA NA 13737 FUN_037941 4071 2939 2153 3340 3409 NA NA NA NA NA NA NA 13738 FUN_037940 62109 24144 36216 76777 54810 ptg000027l:707061-708889 Q964E3 2.29e-175 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 13739 FUN_037940 62109 24144 36216 76777 54810 ptg000027l:707061-708889 Q964E3 5.06e-76 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 13740 FUN_040449 0 0 10 9 19 NA NA NA NA NA NA NA 13741 FUN_037949 14 0 0 0 21 NA NA NA NA NA NA NA 13742 FUN_037948 1530 1036 512 513 615 NA NA NA NA NA NA NA 13743 FUN_021949 170 86 0 159 157 NA NA NA NA NA NA NA 13744 FUN_021940 9112 5943 3129 9812 14198 NA NA NA NA NA NA NA 13745 FUN_021941 29 1 8 34 25 NA NA NA NA NA NA NA 13746 FUN_021945 0 0 9 0 0 NA NA NA NA NA NA NA 13747 FUN_007988 2237 2588 2551 3663 1727 NA NA NA NA NA NA NA 13748 FUN_006042 7127 4864 4006 4434 3850 NA NA NA NA NA NA NA 13749 FUN_006043 0 0 32 0 0 NA NA NA NA NA NA NA 13750 FUN_006040 2771 1989 1618 3124 2837 ptg000001l:7164705-7210554 P97292 6.67e-22 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 13751 FUN_006041 812 762 280 560 162 NA NA NA NA NA NA NA 13752 FUN_006046 0 8 0 0 0 NA NA NA NA NA NA NA 13753 FUN_008374 22 0 0 18 12 NA NA NA NA NA NA NA 13754 FUN_006044 1 0 0 7 2 NA NA NA NA NA NA NA 13755 FUN_005227 2163 1402 1027 2024 1869 NA NA NA NA NA NA NA 13756 FUN_005226 3267 3802 1401 2656 1949 NA NA NA NA NA NA NA 13757 FUN_005225 1755 1352 1506 2231 1005 NA NA NA NA NA NA NA 13758 FUN_005224 0 16 0 18 13 NA NA NA NA NA NA NA 13759 FUN_005223 1950 1456 924 2283 688 ntLink_8:32929480-32930104 P22125 3.94e-93 Ras-related protein ORAB-1 Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005886; GO:0015031 13760 FUN_005222 1922 3022 1044 949 1773 NA NA NA NA NA NA NA 13761 FUN_005221 10 6 1 16 18 NA NA NA NA NA NA NA 13762 FUN_005220 14490 12446 7584 12009 9666 ntLink_8:32908147-32909244 Q06725 1.01e-85 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 13763 FUN_005220 14490 12446 7584 12009 9666 ntLink_8:32908147-32909244 Q06725 7.91e-41 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 13764 FUN_035112 0 0 0 15 0 NA NA NA NA NA NA NA 13765 FUN_008378 15628 557 12364 15203 5054 NA NA NA NA NA NA NA 13766 FUN_005229 5177 7333 3244 6621 3554 NA NA NA NA NA NA NA 13767 FUN_005228 62 162 246 0 0 NA NA NA NA NA NA NA 13768 FUN_004574 3887 2033 1677 2183 2495 NA NA NA NA NA NA NA 13769 FUN_004575 144 248 183 94 66 ntLink_8:24501994-24503138 B5DF45 6.13e-41 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 13770 FUN_004576 2881 2158 1311 2364 2373 ntLink_8:24503920-24508579 Q29503 2.48e-43 Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2) Oryctolagus cuniculus (Rabbit) protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513] GO:0004842; GO:0005524; GO:0006513; GO:0061631; GO:0070936 13771 FUN_004576 2881 2158 1311 2364 2373 ntLink_8:24503920-24508579 Q29503 2.48e-43 Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2) Oryctolagus cuniculus (Rabbit) protein K48-linked ubiquitination [GO:0070936]; protein monoubiquitination [GO:0006513] GO:0004842; GO:0005524; GO:0006513; GO:0061631; GO:0070936 13772 FUN_004577 895 959 766 1402 1499 NA NA NA NA NA NA NA 13773 FUN_004570 3986 2475 2045 4006 2702 NA NA NA NA NA NA NA 13774 FUN_004573 88 80 52 47 88 ntLink_8:24477262-24478819 O73853 7.89e-89 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 13775 FUN_004578 10 5 0 6 12 NA NA NA NA NA NA NA 13776 FUN_004579 631 850 59 229 228 NA NA NA NA NA NA NA 13777 FUN_037055 1475 817 1103 1691 1466 NA NA NA NA NA NA NA 13778 FUN_037054 648 445 335 502 512 ptg000026l:5058300-5066162 Q6NZ22 7.95e-33 N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) Danio rerio (Zebrafish) (Brachydanio rerio) forebrain radial glial cell differentiation [GO:0021861]; gliogenesis [GO:0042063]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; mRNA splicing, via spliceosome [GO:0000398]; RNA methylation [GO:0001510]; spermatogenesis [GO:0007283]; stem cell population maintenance [GO:0019827] GO:0000398; GO:0001510; GO:0001734; GO:0003729; GO:0005634; GO:0007283; GO:0016422; GO:0019827; GO:0021861; GO:0036396; GO:0042063; GO:0061157; GO:0080009 13779 FUN_037057 2150 1204 800 1465 1315 ptg000026l:5081554-5084039 Q62189 1.17e-25 U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A) Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398]; regulation of mRNA polyadenylation [GO:1900363] GO:0000398; GO:0003677; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005685; GO:0030619; GO:0042802; GO:0046540; GO:1900363; GO:1990446 13780 FUN_037056 53031 159039 62675 37320 33835 ptg000026l:5077125-5079732 P35979 1.27e-27 60S ribosomal protein L12 Mus musculus (Mouse) cytoplasmic translation [GO:0002181]; translation [GO:0006412]; translation at postsynapse [GO:0140242]; translation at presynapse [GO:0140236] GO:0002181; GO:0003735; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005840; GO:0006412; GO:0014069; GO:0015934; GO:0022625; GO:0022626; GO:0045202; GO:0070180; GO:0098793; GO:0098794; GO:0140236; GO:0140242 13781 FUN_037051 1881 2216 842 1439 1219 NA NA NA NA NA NA NA 13782 FUN_037050 114 67 63 18 27 NA NA NA NA NA NA NA 13783 FUN_037053 2949 2012 1387 2243 2029 NA NA NA NA NA NA NA 13784 FUN_037052 2099 1567 1527 2422 3021 NA NA NA NA NA NA NA 13785 FUN_037059 1643 666 511 738 190 NA NA NA NA NA NA NA 13786 FUN_037058 709 178 383 458 1010 NA NA NA NA NA NA NA 13787 FUN_006597 103 39 61 79 71 NA NA NA NA NA NA NA 13788 FUN_032669 32 16 74 5 0 NA NA NA NA NA NA NA 13789 FUN_006591 33 76 2 20 138 NA NA NA NA NA NA NA 13790 FUN_006592 32 12 90 0 54 NA NA NA NA NA NA NA 13791 FUN_000140 2 0 4 0 13 ntLink_4:210640-213208 P84239 4.97e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13792 FUN_032666 0 0 0 14 0 NA NA NA NA NA NA NA 13793 FUN_006598 0 0 0 22 10 NA NA NA NA NA NA NA 13794 FUN_032660 0 0 32 0 0 NA NA NA NA NA NA NA 13795 FUN_032663 29 9 13 0 0 NA NA NA NA NA NA NA 13796 FUN_032662 88 73 67 0 0 NA NA NA NA NA NA NA 13797 FUN_000142 29 0 48 7 258 ntLink_4:216959-220111 P35061 2.57e-76 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13798 FUN_005396 0 0 10 0 9 NA NA NA NA NA NA NA 13799 FUN_034626 0 23 0 0 26 NA NA NA NA NA NA NA 13800 FUN_034625 0 9 0 17 0 NA NA NA NA NA NA NA 13801 FUN_034623 0 10 0 22 105 NA NA NA NA NA NA NA 13802 FUN_034622 0 0 7 0 30 NA NA NA NA NA NA NA 13803 FUN_034621 0 6 3 0 28 NA NA NA NA NA NA NA 13804 FUN_019423 3 0 7 44 60 NA NA NA NA NA NA NA 13805 FUN_034628 0 0 0 0 10 NA NA NA NA NA NA NA 13806 FUN_005483 44 2 0 0 4 NA NA NA NA NA NA NA 13807 FUN_005482 0 0 0 0 17 NA NA NA NA NA NA NA 13808 FUN_005481 206 67 237 241 304 NA NA NA NA NA NA NA 13809 FUN_005480 180 55 58 190 131 NA NA NA NA NA NA NA 13810 FUN_005487 4 0 0 2 17 NA NA NA NA NA NA NA 13811 FUN_005486 165 59 27 157 180 NA NA NA NA NA NA NA 13812 FUN_005485 18 0 36 0 0 NA NA NA NA NA NA NA 13813 FUN_005484 7 0 4 20 64 NA NA NA NA NA NA NA 13814 FUN_005488 1 1 5 0 16 NA NA NA NA NA NA NA 13815 FUN_041374 60 0 4 13 13 NA NA NA NA NA NA NA 13816 FUN_007885 0 0 24 0 49 NA NA NA NA NA NA NA 13817 FUN_007884 0 0 0 43 68 NA NA NA NA NA NA NA 13818 FUN_007887 247 0 64 89 103 NA NA NA NA NA NA NA 13819 FUN_007886 3 0 0 0 31 NA NA NA NA NA NA NA 13820 FUN_007881 0 0 0 73 0 NA NA NA NA NA NA NA 13821 FUN_007880 52 35 9 35 92 NA NA NA NA NA NA NA 13822 FUN_007883 96 48 14 116 229 NA NA NA NA NA NA NA 13823 FUN_007882 0 34 0 0 0 NA NA NA NA NA NA NA 13824 FUN_041372 96 72 91 143 179 NA NA NA NA NA NA NA 13825 FUN_007889 25 0 47 0 24 NA NA NA NA NA NA NA 13826 FUN_007888 1676 594 826 1865 2127 NA NA NA NA NA NA NA 13827 FUN_041937 3597 10 6 9 0 NA NA NA NA NA NA NA 13828 FUN_041936 1069 0 0 4 0 NA NA NA NA NA NA NA 13829 FUN_041935 6000 4681 3707 5390 5811 NA NA NA NA NA NA NA 13830 FUN_041934 78 16 6 21 91 NA NA NA NA NA NA NA 13831 FUN_041933 2351 1904 1314 2173 1611 NA NA NA NA NA NA NA 13832 FUN_041932 2585 1821 1196 1887 1769 ptg000035l:9013640-9026011 P53356 1.66e-36 Tyrosine-protein kinase HTK16 (EC 2.7.10.2) Hydra vulgaris (Hydra) (Hydra attenuata) NA GO:0004715; GO:0005524 13833 FUN_041930 2052 1966 1399 1697 730 NA NA NA NA NA NA NA 13834 FUN_041939 628 275 270 379 593 NA NA NA NA NA NA NA 13835 FUN_041938 1498 1001 501 858 689 ptg000035l:9104029-9105615 Q5I0S8 2.09e-72 Leukocyte elastase inhibitor (Serpin B1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005615; GO:0005737; GO:0010466 13836 FUN_001065 5723 3718 3566 6718 5403 NA NA NA NA NA NA NA 13837 FUN_001064 11038 8042 4513 9240 7125 NA NA NA NA NA NA NA 13838 FUN_001067 507 185 172 313 459 NA NA NA NA NA NA NA 13839 FUN_004688 30 0 13 21 26 NA NA NA NA NA NA NA 13840 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 6.04e-111 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13841 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.02e-106 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13842 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.8e-105 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13843 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.61e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13844 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.08e-88 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13845 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.96e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13846 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 7.69e-51 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13847 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13848 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 2.76e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13849 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 6.02e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13850 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 2.09e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13851 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 3.48e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13852 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 5.62e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13853 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 7.18e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13854 FUN_004686 2877 885 1121 1786 1791 ntLink_8:25693830-25713375 P10079 1.62e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 13855 FUN_004687 1514 654 646 1459 835 NA NA NA NA NA NA NA 13856 FUN_004682 534 569 190 385 204 NA NA NA NA NA NA NA 13857 FUN_001068 1815 1519 1044 1708 1627 ntLink_6:8169959-8198441 Q92621 8.37e-51 Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205) Homo sapiens (Human) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0005635; GO:0005643; GO:0005829; GO:0006913; GO:0006999; GO:0015031; GO:0016020; GO:0017056; GO:0031965; GO:0034399; GO:0044611; GO:0051028; GO:0051292 13858 FUN_001068 1815 1519 1044 1708 1627 ntLink_6:8169959-8198441 Q92621 9.75e-33 Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205) Homo sapiens (Human) mRNA transport [GO:0051028]; nuclear pore complex assembly [GO:0051292]; nuclear pore organization [GO:0006999]; nucleocytoplasmic transport [GO:0006913]; protein transport [GO:0015031] GO:0005635; GO:0005643; GO:0005829; GO:0006913; GO:0006999; GO:0015031; GO:0016020; GO:0017056; GO:0031965; GO:0034399; GO:0044611; GO:0051028; GO:0051292 13859 FUN_004681 8 11 14 7 16 NA NA NA NA NA NA NA 13860 FUN_034083 932 707 346 800 439 NA NA NA NA NA NA NA 13861 FUN_034082 684 412 421 1067 414 ptg000024l:4656104-4678094 Q3MV19 1.49e-37 TNF receptor-associated factor 6-A (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6-A) Xenopus laevis (African clawed frog) activation of NF-kappaB-inducing kinase activity [GO:0007250]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122] GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005938; GO:0007250; GO:0008270; GO:0042981; GO:0043122; GO:0070534 13862 FUN_034087 190 192 224 285 239 ptg000024l:4705345-4711591 Q2S1V4 4.38e-152 Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase) Salinibacter ruber (strain DSM 13855 / M31) NA GO:0009034 13863 FUN_034086 0 20 0 69 10 ptg000024l:4700186-4702859 Q0C406 7.11e-139 Tryptophanase (EC 4.1.99.1) (L-tryptophan indole-lyase) (TNase) Hyphomonas neptunium (strain ATCC 15444) NA GO:0009034 13864 FUN_034085 1688 1576 1052 1222 1491 NA NA NA NA NA NA NA 13865 FUN_034084 658 800 401 772 689 ptg000024l:4684338-4691005 P07607 2.09e-27 Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) Mus musculus (Mouse) aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; methylation [GO:0032259]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860] GO:0000900; GO:0003729; GO:0004799; GO:0005542; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006231; GO:0006235; GO:0006417; GO:0007568; GO:0007623; GO:0009410; GO:0009636; GO:0017148; GO:0019860; GO:0032259; GO:0032570; GO:0033189; GO:0034097; GO:0035999; GO:0042803; GO:0045471; GO:0046683; GO:0048589; GO:0051216; GO:0051384; GO:0051593; GO:0060574; GO:0097421; GO:1901363; GO:1990825 13866 FUN_034084 658 800 401 772 689 ptg000024l:4684338-4691005 P07607 1.56e-23 Thymidylate synthase (TS) (TSase) (EC 2.1.1.45) Mus musculus (Mouse) aging [GO:0007568]; cartilage development [GO:0051216]; circadian rhythm [GO:0007623]; developmental growth [GO:0048589]; dTMP biosynthetic process [GO:0006231]; dTTP biosynthetic process [GO:0006235]; intestinal epithelial cell maturation [GO:0060574]; liver regeneration [GO:0097421]; methylation [GO:0032259]; negative regulation of translation [GO:0017148]; regulation of translation [GO:0006417]; response to cytokine [GO:0034097]; response to ethanol [GO:0045471]; response to folic acid [GO:0051593]; response to glucocorticoid [GO:0051384]; response to organophosphorus [GO:0046683]; response to progesterone [GO:0032570]; response to toxic substance [GO:0009636]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; tetrahydrofolate interconversion [GO:0035999]; uracil metabolic process [GO:0019860] GO:0000900; GO:0003729; GO:0004799; GO:0005542; GO:0005634; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006231; GO:0006235; GO:0006417; GO:0007568; GO:0007623; GO:0009410; GO:0009636; GO:0017148; GO:0019860; GO:0032259; GO:0032570; GO:0033189; GO:0034097; GO:0035999; GO:0042803; GO:0045471; GO:0046683; GO:0048589; GO:0051216; GO:0051384; GO:0051593; GO:0060574; GO:0097421; GO:1901363; GO:1990825 13867 FUN_034089 1909 1183 810 1041 691 NA NA NA NA NA NA NA 13868 FUN_034088 4530 2537 1893 2584 1911 ptg000024l:4712778-4720981 Q9DDA9 3.68e-63 Protein kinase C and casein kinase substrate in neurons protein 2 (x-PACSIN2) Xenopus laevis (African clawed frog) actin cytoskeleton organization [GO:0030036]; caveola assembly [GO:0070836]; endocytosis [GO:0006897]; plasma membrane tubulation [GO:0097320] GO:0005769; GO:0005856; GO:0005901; GO:0006897; GO:0030036; GO:0032587; GO:0055038; GO:0070300; GO:0070836; GO:0097320 13869 FUN_043706 0 0 0 0 105 NA NA NA NA NA NA NA 13870 FUN_035974 22 176 43 128 125 NA NA NA NA NA NA NA 13871 FUN_035975 915 419 668 1827 1460 ptg000025l:14127563-14137126 Q7TNH6 3.48e-48 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13872 FUN_035975 915 419 668 1827 1460 ptg000025l:14127563-14137126 Q7TNH6 1.82e-45 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13873 FUN_035975 915 419 668 1827 1460 ptg000025l:14127563-14137126 Q7TNH6 1.19e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13874 FUN_035975 915 419 668 1827 1460 ptg000025l:14127563-14137126 Q7TNH6 4.16e-43 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13875 FUN_035975 915 419 668 1827 1460 ptg000025l:14127563-14137126 Q7TNH6 7.47e-41 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13876 FUN_035975 915 419 668 1827 1460 ptg000025l:14127563-14137126 Q7TNH6 1.07e-39 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 13877 FUN_035976 5355 4099 1422 2597 1405 NA NA NA NA NA NA NA 13878 FUN_035977 684 314 371 486 377 NA NA NA NA NA NA NA 13879 FUN_035970 50 4 3 10 4 NA NA NA NA NA NA NA 13880 FUN_035971 976 568 352 1008 741 ptg000025l:14094431-14095370 Q864U8 9.25e-33 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) Sus scrofa (Pig) brain development [GO:0007420]; central nervous system development [GO:0007417]; lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0007417; GO:0007420; GO:0008457; GO:0016757; GO:0047256 13881 FUN_035972 452 268 297 271 458 NA NA NA NA NA NA NA 13882 FUN_035973 6176 5562 2353 5734 3014 NA NA NA NA NA NA NA 13883 FUN_035978 2160 1770 1376 1942 1310 NA NA NA NA NA NA NA 13884 FUN_035979 194 204 124 289 318 NA NA NA NA NA NA NA 13885 FUN_009570 221 11 66 21 0 NA NA NA NA NA NA NA 13886 FUN_009577 1 0 0 0 6 NA NA NA NA NA NA NA 13887 FUN_025967 62 5 0 8 33 NA NA NA NA NA NA NA 13888 FUN_009575 239 157 9 340 36 ptg000004l:8775185-8779603 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13889 FUN_009575 239 157 9 340 36 ptg000004l:8775185-8779603 Q96AY4 2.4e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13890 FUN_009575 239 157 9 340 36 ptg000004l:8775185-8779603 Q96AY4 4e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13891 FUN_009575 239 157 9 340 36 ptg000004l:8775185-8779603 Q96AY4 5.59e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13892 FUN_029207 1553 708 685 1419 1086 NA NA NA NA NA NA NA 13893 FUN_029206 312 95 192 259 281 NA NA NA NA NA NA NA 13894 FUN_029205 743 489 413 667 605 NA NA NA NA NA NA NA 13895 FUN_029204 859 583 369 589 178 NA NA NA NA NA NA NA 13896 FUN_029203 653 278 201 527 393 NA NA NA NA NA NA NA 13897 FUN_029202 305 62 105 210 156 NA NA NA NA NA NA NA 13898 FUN_029201 2746 1540 1616 3501 3014 ptg000022l:9202326-9237064 Q8C6S9 8.8e-32 Cilia- and flagella-associated protein 54 Mus musculus (Mouse) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0005576; GO:0005930; GO:0007283; GO:0051649; GO:0060271; GO:0060294; GO:0090660; GO:0120197; GO:0120316 13899 FUN_029201 2746 1540 1616 3501 3014 ptg000022l:9202326-9237064 Q8C6S9 1.07e-24 Cilia- and flagella-associated protein 54 Mus musculus (Mouse) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0005576; GO:0005930; GO:0007283; GO:0051649; GO:0060271; GO:0060294; GO:0090660; GO:0120197; GO:0120316 13900 FUN_029201 2746 1540 1616 3501 3014 ptg000022l:9202326-9237064 Q8C6S9 1.07e-24 Cilia- and flagella-associated protein 54 Mus musculus (Mouse) cerebrospinal fluid circulation [GO:0090660]; cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; establishment of localization in cell [GO:0051649]; mucociliary clearance [GO:0120197]; sperm flagellum assembly [GO:0120316]; spermatogenesis [GO:0007283] GO:0005576; GO:0005930; GO:0007283; GO:0051649; GO:0060271; GO:0060294; GO:0090660; GO:0120197; GO:0120316 13901 FUN_029200 861 921 988 1217 1378 ptg000022l:9190358-9201394 Q0DXS3 5.01e-42 Probable RNA-dependent RNA polymerase 1 (OsRDR1) (EC 2.7.7.48) Oryza sativa subsp. japonica (Rice) positive regulation of post-transcriptional gene silencing [GO:0060148]; response to salicylic acid [GO:0009751]; response to virus [GO:0009615]; siRNA processing [GO:0030422]; wax biosynthetic process [GO:0010025] GO:0003723; GO:0003968; GO:0009615; GO:0009751; GO:0010025; GO:0030422; GO:0031380; GO:0060148 13902 FUN_025968 2473 1831 847 2422 1527 ptg000020l:2635284-2643804 Q70JA7 6.6e-39 Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0008376; GO:0030206; GO:0032580; GO:0046872; GO:0047238; GO:0050510 13903 FUN_029209 145 354 200 594 443 NA NA NA NA NA NA NA 13904 FUN_029208 435 169 267 345 518 NA NA NA NA NA NA NA 13905 FUN_000459 142 44 37 65 454 NA NA NA NA NA NA NA 13906 FUN_000458 0 23 18 0 24 NA NA NA NA NA NA NA 13907 FUN_043395 26 0 33 34 13 NA NA NA NA NA NA NA 13908 FUN_043394 13 0 23 11 11 NA NA NA NA NA NA NA 13909 FUN_043397 1117 545 452 904 237 NA NA NA NA NA NA NA 13910 FUN_043396 7008 3843 3279 4495 1561 NA NA NA NA NA NA NA 13911 FUN_043391 4904 4340 2323 4582 3640 ptg000047l:7888876-7891168 Q9VVE5 3.08e-28 RNA-binding protein Musashi homolog Rbp6 Drosophila melanogaster (Fruit fly) regulation of translation [GO:0006417]; stem cell development [GO:0048864] GO:0003727; GO:0003729; GO:0005737; GO:0005844; GO:0006417; GO:0008266; GO:0048864 13912 FUN_043390 3466 979 1197 1967 1876 NA NA NA NA NA NA NA 13913 FUN_012479 4306 3070 2675 3984 2959 NA NA NA NA NA NA NA 13914 FUN_012476 2284 4475 936 2073 1781 ptg000008l:9247906-9249551 Q5M883 5.4e-22 Chloride intracellular channel protein 2 Rattus norvegicus (Rat) chloride transport [GO:0006821]; negative regulation of ryanodine-sensitive calcium-release channel activity [GO:0060315]; positive regulation of binding [GO:0051099]; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0010880] GO:0004602; GO:0005244; GO:0005254; GO:0005737; GO:0006821; GO:0010880; GO:0016020; GO:0034707; GO:0051099; GO:0060315 13915 FUN_012477 4725 4418 2483 3518 3356 NA NA NA NA NA NA NA 13916 FUN_012474 2425 589 821 1578 625 ptg000008l:9228493-9235608 Q9XTR8 4.55e-32 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 13917 FUN_012475 939 482 428 726 515 NA NA NA NA NA NA NA 13918 FUN_043399 2051 1697 1302 1983 1982 NA NA NA NA NA NA NA 13919 FUN_012470 397 734 119 387 372 ptg000008l:9209811-9214981 Q9XTR8 5.77e-25 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 13920 FUN_012471 137 153 192 236 300 ptg000008l:9215306-9216413 Q9XTR8 3.11e-34 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 13921 FUN_000453 14 0 18 10 53 NA NA NA NA NA NA NA 13922 FUN_006868 1500 1079 922 1789 1072 NA NA NA NA NA NA NA 13923 FUN_006869 590 390 280 1645 434 NA NA NA NA NA NA NA 13924 FUN_016508 720 569 263 324 181 ptg000011l:4184387-4186441 A4IGM4 1.22e-28 Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005576; GO:0016491 13925 FUN_016509 212 110 266 170 255 ptg000011l:4186643-4189160 Q09325 2.32e-84 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049] GO:0000139; GO:0001701; GO:0003827; GO:0005794; GO:0006049; GO:0006486; GO:0006487; GO:0008375; GO:0018279; GO:0030145; GO:0048471 13926 FUN_016509 212 110 266 170 255 ptg000011l:4186643-4189160 Q09325 2.78e-40 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049] GO:0000139; GO:0001701; GO:0003827; GO:0005794; GO:0006049; GO:0006486; GO:0006487; GO:0008375; GO:0018279; GO:0030145; GO:0048471 13927 FUN_006864 16498 9305 5770 10778 5497 ptg000001l:17540160-17582910 P14381 1.03e-80 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 13928 FUN_006864 16498 9305 5770 10778 5497 ptg000001l:17540160-17582910 P14381 1.03e-80 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 13929 FUN_006864 16498 9305 5770 10778 5497 ptg000001l:17540160-17582910 P14381 1.03e-80 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 13930 FUN_016507 357 263 206 198 313 ptg000011l:4181742-4184097 A4IGM4 8.32e-28 Hydroxysteroid 11-beta-dehydrogenase 1-like protein (EC 1.1.1.-) (11-beta-hydroxysteroid dehydrogenase type 3) (11-DH3) (11-beta-HSD3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005576; GO:0016491 13931 FUN_006866 172 198 153 1124 751 NA NA NA NA NA NA NA 13932 FUN_016505 12 108 152 36 100 NA NA NA NA NA NA NA 13933 FUN_016500 1710 374 611 467 585 ptg000011l:3870864-3903403 Q5I597 6.1e-34 Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) Bos taurus (Bovine) amino-acid betaine catabolic process [GO:0006579]; L-methionine salvage [GO:0071267]; methionine biosynthetic process [GO:0009086]; methylation [GO:0032259] GO:0005634; GO:0005829; GO:0006579; GO:0008270; GO:0009086; GO:0032259; GO:0047150; GO:0071267 13934 FUN_016501 117 106 75 74 114 NA NA NA NA NA NA NA 13935 FUN_000450 17 20 0 104 94 NA NA NA NA NA NA NA 13936 FUN_035028 40 36 41 32 125 NA NA NA NA NA NA NA 13937 FUN_035029 29 27 0 47 36 NA NA NA NA NA NA NA 13938 FUN_035020 68 7 24 86 0 NA NA NA NA NA NA NA 13939 FUN_035021 42 136 13 78 66 NA NA NA NA NA NA NA 13940 FUN_035026 490 774 192 417 209 NA NA NA NA NA NA NA 13941 FUN_035027 222 45 0 0 31 NA NA NA NA NA NA NA 13942 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 2.27e-31 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13943 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 7.42e-30 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13944 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 3.39e-29 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13945 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 8.53e-29 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13946 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 2.44e-28 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13947 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 3.61e-22 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13948 FUN_035024 95 129 28 163 52 ptg000025l:2956916-3049968 P30974 3.61e-22 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13949 FUN_035025 2594 5460 1977 1730 2020 NA NA NA NA NA NA NA 13950 FUN_003339 0 0 0 0 59 NA NA NA NA NA NA NA 13951 FUN_027378 1 16 71 31 1 NA NA NA NA NA NA NA 13952 FUN_028154 6047 5750 4740 11098 5931 NA NA NA NA NA NA NA 13953 FUN_028155 25 59 2 128 81 NA NA NA NA NA NA NA 13954 FUN_028156 420 385 126 755 441 NA NA NA NA NA NA NA 13955 FUN_028157 1132 589 593 1093 769 NA NA NA NA NA NA NA 13956 FUN_028150 846 552 844 1403 1332 NA NA NA NA NA NA NA 13957 FUN_028151 188 298 219 245 172 ptg000021l:16267530-16272576 Q9YGL3 6.95e-31 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 13958 FUN_028151 188 298 219 245 172 ptg000021l:16267530-16272576 Q9YGL3 4.83e-25 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 13959 FUN_028152 238 267 205 254 113 NA NA NA NA NA NA NA 13960 FUN_028158 2481 1500 1374 1625 1034 NA NA NA NA NA NA NA 13961 FUN_041444 363 1636 170 390 264 NA NA NA NA NA NA NA 13962 FUN_041442 107 135 86 73 138 ptg000035l:3746108-3748809 Q08623 3.68e-38 Pseudouridine-5'-phosphatase (EC 3.1.3.96) (Haloacid dehalogenase-like hydrolase domain-containing protein 1) (Haloacid dehalogenase-like hydrolase domain-containing protein 1A) (Protein GS1) (Pseudouridine-5'-monophosphatase) (5'-PsiMPase) Homo sapiens (Human) nucleotide metabolic process [GO:0009117] GO:0005829; GO:0009117; GO:0016791; GO:0046872; GO:1990738 13963 FUN_005642 0 0 3 0 18 NA NA NA NA NA NA NA 13964 FUN_038091 133247 330602 167040 125031 96467 ptg000027l:2259030-2260561 B4PEU8 1.35e-74 40S ribosomal protein S9 Drosophila yakuba (Fruit fly) translation [GO:0006412] GO:0000228; GO:0003735; GO:0005730; GO:0006412; GO:0015935; GO:0019843; GO:0022626 13965 FUN_038092 1406 1742 1211 1063 987 NA NA NA NA NA NA NA 13966 FUN_010830 2914 2732 2089 3263 2330 NA NA NA NA NA NA NA 13967 FUN_010831 2282 2158 1674 3434 3245 NA NA NA NA NA NA NA 13968 FUN_010832 13821 10123 7251 10865 6969 ptg000007l:3362088-3366359 Q13118 3.93e-35 Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1) Homo sapiens (Human) bone mineralization [GO:0030282]; cell-cell signaling [GO:0007267]; cellular response to starvation [GO:0009267]; circadian rhythm [GO:0007623]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of circadian rhythm [GO:0042752]; regulation of transcription by RNA polymerase II [GO:0006357]; somatic stem cell population maintenance [GO:0035019] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001046; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0007267; GO:0007623; GO:0008285; GO:0009267; GO:0030282; GO:0035019; GO:0042752; GO:0045672; GO:0045892; GO:0045944; GO:0046872; GO:1990837 13969 FUN_010833 37 1 1 77 38 NA NA NA NA NA NA NA 13970 FUN_010834 81 77 173 232 135 ptg000007l:3378844-3389405 P30974 5.29e-22 Tachykinin-like peptides receptor 86C (NKD) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; inter-male aggressive behavior [GO:0002121]; neuropeptide signaling pathway [GO:0007218]; tachykinin receptor signaling pathway [GO:0007217] GO:0002121; GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020 13971 FUN_010835 656 142 238 558 1048 NA NA NA NA NA NA NA 13972 FUN_010836 178 135 100 403 245 NA NA NA NA NA NA NA 13973 FUN_010837 5355 5656 2256 3648 2508 NA NA NA NA NA NA NA 13974 FUN_043647 3976 1890 969 1896 627 NA NA NA NA NA NA NA 13975 FUN_043646 39 33 21 16 25 NA NA NA NA NA NA NA 13976 FUN_043645 110 171 79 124 9 NA NA NA NA NA NA NA 13977 FUN_043643 967 1594 563 10365 841 NA NA NA NA NA NA NA 13978 FUN_043642 2112 1728 1250 3045 1900 NA NA NA NA NA NA NA 13979 FUN_043641 956 476 467 640 1084 NA NA NA NA NA NA NA 13980 FUN_038097 64 487 488 404 88 NA NA NA NA NA NA NA 13981 FUN_042512 26 1 39 1 86 ptg000037l:189773-190085 Q6LAF1 2.64e-53 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 13982 FUN_009078 71 96 58 36 41 ptg000004l:2457203-2462006 Q96AY4 1.59e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13983 FUN_009078 71 96 58 36 41 ptg000004l:2457203-2462006 Q96AY4 2.87e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13984 FUN_009078 71 96 58 36 41 ptg000004l:2457203-2462006 Q96AY4 8.2e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13985 FUN_009077 4 4 2 13 150 NA NA NA NA NA NA NA 13986 FUN_009074 7 30 17 0 0 NA NA NA NA NA NA NA 13987 FUN_009075 170 177 66 56 92 NA NA NA NA NA NA NA 13988 FUN_009072 64 11 0 2 27 NA NA NA NA NA NA NA 13989 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 5.45e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13990 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 1.36e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13991 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 2.1e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13992 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 9.5e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13993 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 4.8e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13994 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 2.7e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13995 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 9.18e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13996 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 1.37e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13997 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 3.25e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13998 FUN_009073 229 352 64 18 149 ptg000004l:2411039-2414450 Q96AY4 1.41e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 13999 FUN_009070 36 45 75 57 398 NA NA NA NA NA NA NA 14000 FUN_009071 41 104 44 20 129 ptg000004l:2376222-2379093 Q96AY4 2.12e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14001 FUN_009071 41 104 44 20 129 ptg000004l:2376222-2379093 Q96AY4 3.29e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14002 FUN_009071 41 104 44 20 129 ptg000004l:2376222-2379093 Q96AY4 3.33e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14003 FUN_009071 41 104 44 20 129 ptg000004l:2376222-2379093 Q96AY4 1.75e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14004 FUN_009071 41 104 44 20 129 ptg000004l:2376222-2379093 Q96AY4 4.31e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14005 FUN_022149 28 28 19 72 28 NA NA NA NA NA NA NA 14006 FUN_022145 71 44 37 127 27 ptg000016l:5735815-5746404 B8UU78 1.57e-155 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14007 FUN_022145 71 44 37 127 27 ptg000016l:5735815-5746404 B8UU78 2.5e-103 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14008 FUN_022145 71 44 37 127 27 ptg000016l:5735815-5746404 B8UU78 4.68e-80 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14009 FUN_022145 71 44 37 127 27 ptg000016l:5735815-5746404 B8UU78 3.22e-24 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14010 FUN_022144 878 53 0 0 90 NA NA NA NA NA NA NA 14011 FUN_022147 26 0 24 0 16 ptg000016l:5753871-5756634 B8UU78 7.05e-169 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14012 FUN_022147 26 0 24 0 16 ptg000016l:5753871-5756634 B8UU78 1.03e-28 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14013 FUN_022142 8 0 0 0 0 NA NA NA NA NA NA NA 14014 FUN_023642 2265 1706 1054 1096 1062 ptg000017l:10229824-10231022 P81192 8.2e-25 Homeobox protein Hox-A4 (LsHox 4) Lineus sanguineus (Ribbon worm) NA GO:0000981; GO:0003677; GO:0005634 14015 FUN_040606 0 0 0 13 4 NA NA NA NA NA NA NA 14016 FUN_010167 22 0 0 0 19 NA NA NA NA NA NA NA 14017 FUN_040605 2 0 50 0 13 NA NA NA NA NA NA NA 14018 FUN_040603 10 32 45 0 3 NA NA NA NA NA NA NA 14019 FUN_040600 0 0 0 0 26 NA NA NA NA NA NA NA 14020 FUN_040601 0 0 63 0 0 NA NA NA NA NA NA NA 14021 FUN_010168 19 0 0 0 0 NA NA NA NA NA NA NA 14022 FUN_012995 22 2 19 5 85 NA NA NA NA NA NA NA 14023 FUN_012994 7 5 11 0 8 NA NA NA NA NA NA NA 14024 FUN_012991 35 4 1 85 7 NA NA NA NA NA NA NA 14025 FUN_012990 59 20 22 34 15 NA NA NA NA NA NA NA 14026 FUN_012993 0 0 0 0 22 NA NA NA NA NA NA NA 14027 FUN_012992 0 0 0 0 7 NA NA NA NA NA NA NA 14028 FUN_000985 206 79 113 77 203 NA NA NA NA NA NA NA 14029 FUN_009929 0 0 0 0 9 NA NA NA NA NA NA NA 14030 FUN_029307 343 271 96 298 306 NA NA NA NA NA NA NA 14031 FUN_000986 26 17 20 2 18 NA NA NA NA NA NA NA 14032 FUN_029302 3 81 22 189 149 NA NA NA NA NA NA NA 14033 FUN_024420 144 3115 218 8499 4356 NA NA NA NA NA NA NA 14034 FUN_024421 0 0 0 11 4 NA NA NA NA NA NA NA 14035 FUN_024422 0 0 1036 31 31 NA NA NA NA NA NA NA 14036 FUN_024423 0 22 0 12 13 NA NA NA NA NA NA NA 14037 FUN_024424 483 3478 43260 9513 4201 ptg000018l:6133148-6193465 P08548 7.65e-21 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 14038 FUN_029300 35 46 58 55 158 NA NA NA NA NA NA NA 14039 FUN_024426 76 21 15892 297 369 NA NA NA NA NA NA NA 14040 FUN_024427 7714 2602 36853 7665 3958 NA NA NA NA NA NA NA 14041 FUN_024428 864 1474 38435 4162 2274 NA NA NA NA NA NA NA 14042 FUN_024429 165000 63995 165445 154454 78110 NA NA NA NA NA NA NA 14043 FUN_032340 41 41 37 31 63 NA NA NA NA NA NA NA 14044 FUN_032346 1900 2284 2007 1412 1065 NA NA NA NA NA NA NA 14045 FUN_032347 2394 1858 1060 1410 1227 NA NA NA NA NA NA NA 14046 FUN_032344 1428 1146 818 1576 1576 NA NA NA NA NA NA NA 14047 FUN_032345 1933 763 828 865 825 ptg000023l:31041463-31051515 Q9V3L1 1.28e-37 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)] Drosophila melanogaster (Fruit fly) epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; mesoderm migration involved in gastrulation [GO:0007509]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; Wnt signaling pathway [GO:0016055] GO:0000137; GO:0000139; GO:0005783; GO:0005794; GO:0006024; GO:0006790; GO:0007283; GO:0007367; GO:0007427; GO:0007474; GO:0007509; GO:0008146; GO:0008543; GO:0008587; GO:0015012; GO:0015014; GO:0015016; GO:0016055; GO:0019213; GO:0030210; GO:0045570; GO:0102140 14048 FUN_032345 1933 763 828 865 825 ptg000023l:31041463-31051515 Q9V3L1 6.81e-23 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase) (Sulfateless) [Includes: Heparan sulfate N-deacetylase (EC 3.-.-.-); Heparan sulfate N-sulfotransferase (EC 2.8.2.-)] Drosophila melanogaster (Fruit fly) epithelial cell migration, open tracheal system [GO:0007427]; fibroblast growth factor receptor signaling pathway [GO:0008543]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing vein specification [GO:0007474]; mesoderm migration involved in gastrulation [GO:0007509]; regulation of imaginal disc growth [GO:0045570]; segment polarity determination [GO:0007367]; spermatogenesis [GO:0007283]; sulfur compound metabolic process [GO:0006790]; Wnt signaling pathway [GO:0016055] GO:0000137; GO:0000139; GO:0005783; GO:0005794; GO:0006024; GO:0006790; GO:0007283; GO:0007367; GO:0007427; GO:0007474; GO:0007509; GO:0008146; GO:0008543; GO:0008587; GO:0015012; GO:0015014; GO:0015016; GO:0016055; GO:0019213; GO:0030210; GO:0045570; GO:0102140 14049 FUN_038700 71 37 33 12 2 ptg000027l:10316010-10317522 Q49SH1 9.66e-100 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 14050 FUN_038701 0 0 0 16 0 ptg000027l:10320587-10321976 Q8C261 2.32e-88 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5) Mus musculus (Mouse) calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; negative regulation of melanin biosynthetic process [GO:0048022]; response to stimulus [GO:0050896] GO:0005262; GO:0005802; GO:0006874; GO:0008273; GO:0015085; GO:0015293; GO:0016020; GO:0030318; GO:0034220; GO:0042438; GO:0042470; GO:0048022; GO:0050896; GO:0070509; GO:0070588 14051 FUN_038702 24 22 13 21 24 NA NA NA NA NA NA NA 14052 FUN_038703 116 75 43 32 11 ptg000027l:10327537-10327981 Q9HC58 6.97e-49 Sodium/potassium/calcium exchanger 3 (Na(+)/K(+)/Ca(2+)-exchange protein 3) (Solute carrier family 24 member 3) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transport [GO:0006811]; negative regulation of gene expression [GO:0010629]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725]; transport across blood-brain barrier [GO:0150104] GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0008273; GO:0010628; GO:0010629; GO:0015293; GO:0030282; GO:0035725; GO:0070588; GO:0071805; GO:0071944; GO:0150104 14053 FUN_038705 17 21 9 94 104 NA NA NA NA NA NA NA 14054 FUN_038706 199 122 140 619 180 ptg000027l:10338633-10341781 Q71RS6 1.29e-113 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Solute carrier family 24 member 5) Homo sapiens (Human) calcium ion import [GO:0070509]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; melanin biosynthetic process [GO:0042438]; melanocyte differentiation [GO:0030318]; negative regulation of melanin biosynthetic process [GO:0048022]; response to stimulus [GO:0050896] GO:0005262; GO:0005802; GO:0006811; GO:0006874; GO:0008273; GO:0015293; GO:0030318; GO:0032588; GO:0034220; GO:0042438; GO:0042470; GO:0048022; GO:0050896; GO:0070509; GO:0070588 14055 FUN_038707 269 136 128 402 174 NA NA NA NA NA NA NA 14056 FUN_038708 497 168 218 72 266 ptg000027l:10353304-10371611 B3NDN0 1.99e-79 Kelch-like protein diablo Drosophila erecta (Fruit fly) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein autoubiquitination [GO:0051865] GO:0003779; GO:0042803; GO:0045886; GO:0051865 14057 FUN_038708 497 168 218 72 266 ptg000027l:10353304-10371611 B3NDN0 8.51e-26 Kelch-like protein diablo Drosophila erecta (Fruit fly) negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; protein autoubiquitination [GO:0051865] GO:0003779; GO:0042803; GO:0045886; GO:0051865 14058 FUN_024708 0 59 62 47 28 NA NA NA NA NA NA NA 14059 FUN_028936 0 0 52 0 0 NA NA NA NA NA NA NA 14060 FUN_028937 297 327 71 269 122 ptg000022l:6188303-6194442 P26714 2.92e-21 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004890; GO:0005230; GO:0005254; GO:0034707; GO:0045211 14061 FUN_015075 142 50 21 66 53 ptg000009l:5911808-5912663 P56433 6.11e-44 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 14062 FUN_028935 6 0 0 0 0 NA NA NA NA NA NA NA 14063 FUN_028932 3 3 2 6 56 NA NA NA NA NA NA NA 14064 FUN_028933 22 40 33 51 9 NA NA NA NA NA NA NA 14065 FUN_028930 4 9 0 0 0 NA NA NA NA NA NA NA 14066 FUN_028931 0 18 0 16 53 ptg000022l:6136058-6145012 Q95SX7 8.12e-27 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 14067 FUN_015079 10 0 0 8 0 NA NA NA NA NA NA NA 14068 FUN_015078 271 101 90 186 169 ptg000009l:5933707-5935375 Q8HYJ7 2.24e-45 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 14069 FUN_039382 3 2 14 0 2 NA NA NA NA NA NA NA 14070 FUN_039072 14 0 6 0 46 NA NA NA NA NA NA NA 14071 FUN_039075 22 1 20 6 113 NA NA NA NA NA NA NA 14072 FUN_039079 0 0 0 28 0 NA NA NA NA NA NA NA 14073 FUN_039078 4 26 0 0 0 NA NA NA NA NA NA NA 14074 FUN_040421 40 24 83 114 67 NA NA NA NA NA NA NA 14075 FUN_022969 1055 755 781 2450 1015 NA NA NA NA NA NA NA 14076 FUN_022968 8793 4818 4052 8083 5587 NA NA NA NA NA NA NA 14077 FUN_022967 24 40 7 103 60 NA NA NA NA NA NA NA 14078 FUN_022966 720 437 361 959 764 NA NA NA NA NA NA NA 14079 FUN_022965 1970 2736 1417 3228 2298 NA NA NA NA NA NA NA 14080 FUN_022964 2544 1402 329 1471 782 NA NA NA NA NA NA NA 14081 FUN_022963 39 31 22 59 78 NA NA NA NA NA NA NA 14082 FUN_022962 17030 13836 7651 8317 5604 NA NA NA NA NA NA NA 14083 FUN_022961 30 0 0 71 14 NA NA NA NA NA NA NA 14084 FUN_022960 34 25 65 173 29 NA NA NA NA NA NA NA 14085 FUN_027301 5 42 31 0 14 NA NA NA NA NA NA NA 14086 FUN_027304 12 0 1 0 1 NA NA NA NA NA NA NA 14087 FUN_027305 0 0 6 0 0 NA NA NA NA NA NA NA 14088 FUN_027306 10 0 12 0 0 NA NA NA NA NA NA NA 14089 FUN_027309 30 0 0 0 0 NA NA NA NA NA NA NA 14090 FUN_016744 2458 1204 843 1276 1115 NA NA NA NA NA NA NA 14091 FUN_017325 0 0 0 0 6 NA NA NA NA NA NA NA 14092 FUN_017327 0 0 0 0 8 NA NA NA NA NA NA NA 14093 FUN_017326 0 0 0 0 12 NA NA NA NA NA NA NA 14094 FUN_017329 0 4 5 0 11 NA NA NA NA NA NA NA 14095 FUN_038889 523 705 715 598 973 ptg000027l:12467102-12468491 A4IF63 1.11e-30 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 14096 FUN_038888 22 0 7 0 9 NA NA NA NA NA NA NA 14097 FUN_038887 1593 1451 360 1287 666 NA NA NA NA NA NA NA 14098 FUN_038886 1799 718 667 949 1188 NA NA NA NA NA NA NA 14099 FUN_038883 2266 5280 3466 18296 9391 NA NA NA NA NA NA NA 14100 FUN_038882 2 7 44 0 9 NA NA NA NA NA NA NA 14101 FUN_007165 51 3 84 22 239 NA NA NA NA NA NA NA 14102 FUN_003189 2 8 0 5 69 NA NA NA NA NA NA NA 14103 FUN_042485 13 0 35 1 171 NA NA NA NA NA NA NA 14104 FUN_027876 0 9 0 0 18 NA NA NA NA NA NA NA 14105 FUN_027874 0 0 0 26 2 NA NA NA NA NA NA NA 14106 FUN_027875 0 0 0 10 14 NA NA NA NA NA NA NA 14107 FUN_027872 26 54 27 13 0 NA NA NA NA NA NA NA 14108 FUN_027878 15 33 0 0 7 NA NA NA NA NA NA NA 14109 FUN_014678 0 1 3 6 0 NA NA NA NA NA NA NA 14110 FUN_014679 806 543 465 586 769 NA NA NA NA NA NA NA 14111 FUN_003729 0 2 4 3 27 NA NA NA NA NA NA NA 14112 FUN_014672 619 634 576 607 670 NA NA NA NA NA NA NA 14113 FUN_014673 3800 2005 1536 2530 2009 ptg000009l:2001792-2025171 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14114 FUN_014670 1122 532 876 902 1200 NA NA NA NA NA NA NA 14115 FUN_014671 1738 1308 933 1288 898 NA NA NA NA NA NA NA 14116 FUN_014676 0 6 5 24 7 NA NA NA NA NA NA NA 14117 FUN_014677 82 77 34 119 58 ptg000009l:2056880-2059422 Q9SAL0 9.61e-79 E3 ubiquitin-protein ligase RGLG4 (EC 2.3.2.27) (RING domain ligase 4) Arabidopsis thaliana (Mouse-ear cress) defense response to bacterium [GO:0042742]; jasmonic acid mediated signaling pathway [GO:0009867]; protein K63-linked ubiquitination [GO:0070534]; response to wounding [GO:0009611] GO:0004842; GO:0005634; GO:0005737; GO:0005739; GO:0009611; GO:0009867; GO:0042742; GO:0046872; GO:0061630; GO:0070534 14118 FUN_014674 11481 8984 4406 7467 6061 ptg000009l:2039841-2049694 Q9JKV2 5.66e-24 Serine/threonine-protein kinase ICK (EC 2.7.11.1) (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Mus musculus (Mouse) cilium assembly [GO:0060271]; intracellular signal transduction [GO:0035556]; intraciliary anterograde transport [GO:0035720]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0000287; GO:0001650; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0006468; GO:0007165; GO:0035556; GO:0035720; GO:0035721; GO:0036064; GO:0042073; GO:0060271; GO:0097542; GO:0097546; GO:0106310 14119 FUN_014675 28 0 4 9 16 NA NA NA NA NA NA NA 14120 FUN_023375 28 20 9 44 43 ptg000017l:6802315-6804362 Q804S6 2.87e-23 Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) brain development [GO:0007420]; central nervous system development [GO:0007417]; neuron differentiation [GO:0030182]; pronephric distal tubule development [GO:0035777]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007417; GO:0007420; GO:0030182; GO:0035777 14121 FUN_023374 255 150 145 149 209 NA NA NA NA NA NA NA 14122 FUN_023377 559 370 421 231 237 NA NA NA NA NA NA NA 14123 FUN_023376 761 311 307 375 536 NA NA NA NA NA NA NA 14124 FUN_023371 247 202 124 178 235 ptg000017l:6761871-6774304 Q95SX7 2.91e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 14125 FUN_023370 0 0 0 12 28 NA NA NA NA NA NA NA 14126 FUN_023373 148 72 45 104 95 NA NA NA NA NA NA NA 14127 FUN_023372 2689 3023 1792 2173 1732 NA NA NA NA NA NA NA 14128 FUN_023379 428 259 178 445 194 ptg000017l:6855646-6857814 Q29496 4.53e-70 Cytochrome P450 3A24 (EC 1.14.14.1) (CYPIIIA24) Ovis aries (Sheep) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0070330 14129 FUN_023378 49 26 81 68 70 ptg000017l:6843802-6844768 Q6GLB9 2.09e-26 Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000981; GO:0003677; GO:0005634 14130 FUN_003720 0 0 0 16 0 ntLink_8:14729795-14733312 Q9WTS8 3.87e-43 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 14131 FUN_003720 0 0 0 16 0 ntLink_8:14729795-14733312 Q9WTS8 1.59e-21 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 14132 FUN_004113 13 12 6 7 0 NA NA NA NA NA NA NA 14133 FUN_004110 766 460 394 898 302 ntLink_8:19358399-19359897 Q5ZL21 7.07e-69 Cyanocobalamin reductase / alkylcobalamin dealkylase (Alkylcobalamin:glutathione S-alkyltransferase) (EC 2.5.1.151) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) (EC 1.16.1.6) (Methylmalonic aciduria and homocystinuria type C protein) (MMACHC) Gallus gallus (Chicken) cobalamin metabolic process [GO:0009235]; demethylation [GO:0070988]; glutathione metabolic process [GO:0006749] GO:0005737; GO:0005829; GO:0006749; GO:0009235; GO:0016491; GO:0016740; GO:0031419; GO:0032451; GO:0033787; GO:0043295; GO:0070988; GO:0071949 14134 FUN_004111 1265 1149 1634 1099 646 NA NA NA NA NA NA NA 14135 FUN_036721 0 0 0 0 19 NA NA NA NA NA NA NA 14136 FUN_003724 0 159 39 0 0 NA NA NA NA NA NA NA 14137 FUN_003725 4 0 0 2 53 NA NA NA NA NA NA NA 14138 FUN_003726 0 0 0 0 9 NA NA NA NA NA NA NA 14139 FUN_004115 1461 1006 1222 1073 2665 NA NA NA NA NA NA NA 14140 FUN_019369 48 59 0 0 0 NA NA NA NA NA NA NA 14141 FUN_019368 109 39 40 5 16 NA NA NA NA NA NA NA 14142 FUN_019363 0 90 0 0 60 NA NA NA NA NA NA NA 14143 FUN_019367 0 26 0 14 0 NA NA NA NA NA NA NA 14144 FUN_019366 0 104 0 0 87 NA NA NA NA NA NA NA 14145 FUN_019365 0 0 16 0 19 NA NA NA NA NA NA NA 14146 FUN_019364 0 0 0 0 26 NA NA NA NA NA NA NA 14147 FUN_039826 1056 775 816 876 638 ptg000031l:591171-608654 Q27084 5.61e-72 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 14148 FUN_039826 1056 775 816 876 638 ptg000031l:591171-608654 Q27084 2.76e-71 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 14149 FUN_039826 1056 775 816 876 638 ptg000031l:591171-608654 Q27084 4.21e-58 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 14150 FUN_039826 1056 775 816 876 638 ptg000031l:591171-608654 Q27084 5.62e-58 Tachylectin-2 (Lectin L10c) Tachypleus tridentatus (Japanese horseshoe crab) innate immune response [GO:0045087] GO:0005576; GO:0030246; GO:0045087 14151 FUN_039827 2703 1941 1211 2309 1719 ptg000031l:613605-625300 P10447 2.13e-83 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Feline sarcoma virus (strain Hardy-Zuckerman 2) cell communication [GO:0007154]; signaling [GO:0023052] GO:0004715; GO:0005524; GO:0007154; GO:0023052 14152 FUN_039827 2703 1941 1211 2309 1719 ptg000031l:613605-625300 P10447 5.67e-37 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Feline sarcoma virus (strain Hardy-Zuckerman 2) cell communication [GO:0007154]; signaling [GO:0023052] GO:0004715; GO:0005524; GO:0007154; GO:0023052 14153 FUN_039827 2703 1941 1211 2309 1719 ptg000031l:613605-625300 P10447 9.07e-26 Tyrosine-protein kinase transforming protein Abl (EC 2.7.10.2) (V-abl) Feline sarcoma virus (strain Hardy-Zuckerman 2) cell communication [GO:0007154]; signaling [GO:0023052] GO:0004715; GO:0005524; GO:0007154; GO:0023052 14154 FUN_022428 811 965 442 1073 1158 NA NA NA NA NA NA NA 14155 FUN_039825 0 1 5 13 59 NA NA NA NA NA NA NA 14156 FUN_039822 970 684 590 793 330 ptg000031l:545932-551326 O08848 1.71e-70 RNA-binding protein Ro60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Mus musculus (Mouse) cellular response to interferon-alpha [GO:0035457]; cilium assembly [GO:0060271]; immune system development [GO:0002520]; regulation of gene expression [GO:0010468]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224] GO:0002520; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007224; GO:0009411; GO:0010468; GO:0016604; GO:0030620; GO:0034336; GO:0035457; GO:0046872; GO:0060271; GO:1990904 14157 FUN_039822 970 684 590 793 330 ptg000031l:545932-551326 O08848 1.61e-31 RNA-binding protein Ro60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Mus musculus (Mouse) cellular response to interferon-alpha [GO:0035457]; cilium assembly [GO:0060271]; immune system development [GO:0002520]; regulation of gene expression [GO:0010468]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224] GO:0002520; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007224; GO:0009411; GO:0010468; GO:0016604; GO:0030620; GO:0034336; GO:0035457; GO:0046872; GO:0060271; GO:1990904 14158 FUN_039822 970 684 590 793 330 ptg000031l:545932-551326 O08848 1.49e-23 RNA-binding protein Ro60 (60 kDa SS-A/Ro ribonucleoprotein) (60 kDa Ro protein) (60 kDa ribonucleoprotein Ro) (RoRNP) (TROVE domain family member 2) Mus musculus (Mouse) cellular response to interferon-alpha [GO:0035457]; cilium assembly [GO:0060271]; immune system development [GO:0002520]; regulation of gene expression [GO:0010468]; response to UV [GO:0009411]; smoothened signaling pathway [GO:0007224] GO:0002520; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007224; GO:0009411; GO:0010468; GO:0016604; GO:0030620; GO:0034336; GO:0035457; GO:0046872; GO:0060271; GO:1990904 14159 FUN_039823 0 11 0 24 100 NA NA NA NA NA NA NA 14160 FUN_039820 658 399 488 655 929 NA NA NA NA NA NA NA 14161 FUN_039821 422 557 318 236 154 ptg000031l:532588-534246 Q9I8I2 1.79e-21 Bcl-2-related ovarian killer protein Gallus gallus (Chicken) extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; regulation of apoptotic process [GO:0042981] GO:0005741; GO:0008630; GO:0042803; GO:0042981; GO:0046982; GO:0097192 14162 FUN_022423 953 1441 958 2087 2553 NA NA NA NA NA NA NA 14163 FUN_025434 0 28 25 0 16 NA NA NA NA NA NA NA 14164 FUN_025435 150 115 47 98 100 NA NA NA NA NA NA NA 14165 FUN_039828 1693 1332 904 1163 1256 NA NA NA NA NA NA NA 14166 FUN_022425 378 246 271 298 220 NA NA NA NA NA NA NA 14167 FUN_024749 720 1219 223 978 258 NA NA NA NA NA NA NA 14168 FUN_024748 306 161 136 116 216 NA NA NA NA NA NA NA 14169 FUN_024741 265 308 71 183 161 NA NA NA NA NA NA NA 14170 FUN_024740 1291 1034 761 1149 1169 ptg000018l:10504498-10516875 Q5SUR0 6.25e-138 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005737; GO:0006177; GO:0006189; GO:0006541; GO:0009410; GO:0044208; GO:0046872; GO:0097065; GO:0097294 14171 FUN_024740 1291 1034 761 1149 1169 ptg000018l:10504498-10516875 Q5SUR0 2.82e-58 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005737; GO:0006177; GO:0006189; GO:0006541; GO:0009410; GO:0044208; GO:0046872; GO:0097065; GO:0097294 14172 FUN_024740 1291 1034 761 1149 1169 ptg000018l:10504498-10516875 Q5SUR0 8.47e-45 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005737; GO:0006177; GO:0006189; GO:0006541; GO:0009410; GO:0044208; GO:0046872; GO:0097065; GO:0097294 14173 FUN_024740 1291 1034 761 1149 1169 ptg000018l:10504498-10516875 Q5SUR0 3.81e-30 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005737; GO:0006177; GO:0006189; GO:0006541; GO:0009410; GO:0044208; GO:0046872; GO:0097065; GO:0097294 14174 FUN_024740 1291 1034 761 1149 1169 ptg000018l:10504498-10516875 Q5SUR0 5.65e-23 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005737; GO:0006177; GO:0006189; GO:0006541; GO:0009410; GO:0044208; GO:0046872; GO:0097065; GO:0097294 14175 FUN_024740 1291 1034 761 1149 1169 ptg000018l:10504498-10516875 Q5SUR0 4.56e-21 Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT) (Formylglycinamide ribotide amidotransferase) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; anterior head development [GO:0097065]; glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; response to xenobiotic stimulus [GO:0009410] GO:0004642; GO:0005524; GO:0005737; GO:0006177; GO:0006189; GO:0006541; GO:0009410; GO:0044208; GO:0046872; GO:0097065; GO:0097294 14176 FUN_024743 155 47 32 109 119 NA NA NA NA NA NA NA 14177 FUN_024742 2614 1474 833 919 978 NA NA NA NA NA NA NA 14178 FUN_024745 0 1 0 17 0 NA NA NA NA NA NA NA 14179 FUN_024744 106 321 58 594 336 NA NA NA NA NA NA NA 14180 FUN_024747 4 11 2 11 13 NA NA NA NA NA NA NA 14181 FUN_024746 114 1534 143 134 3 NA NA NA NA NA NA NA 14182 FUN_019098 34 0 5 2 278 NA NA NA NA NA NA NA 14183 FUN_019091 22 0 0 0 0 NA NA NA NA NA NA NA 14184 FUN_019090 0 0 0 44 52 NA NA NA NA NA NA NA 14185 FUN_019093 0 6 3 2 0 NA NA NA NA NA NA NA 14186 FUN_019092 0 0 13 0 41 NA NA NA NA NA NA NA 14187 FUN_018064 59 111 33 55 46 NA NA NA NA NA NA NA 14188 FUN_034796 3487 2413 1703 3202 2180 ptg000025l:255146-261866 O95995 3.84e-38 Dynein regulatory complex subunit 4 (Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8) Homo sapiens (Human) axoneme assembly [GO:0035082]; brain development [GO:0007420]; cilium movement involved in cell motility [GO:0060294]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of protein localization to cilium [GO:1903566]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization [GO:0008104]; regulation of microtubule binding [GO:1904526] GO:0003351; GO:0005576; GO:0005794; GO:0005829; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007420; GO:0008017; GO:0008104; GO:0008285; GO:0030317; GO:0031267; GO:0031514; GO:0035082; GO:0036064; GO:0036126; GO:0045880; GO:0051649; GO:0060294; GO:1903566; GO:1904526 14189 FUN_018948 0 25 0 110 0 NA NA NA NA NA NA NA 14190 FUN_018940 9 0 25 12 31 NA NA NA NA NA NA NA 14191 FUN_018941 7 0 64 0 86 NA NA NA NA NA NA NA 14192 FUN_018943 162 22 10 5 66 ptg000012l:15483704-15492959 P04323 4.51e-57 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14193 FUN_018943 162 22 10 5 66 ptg000012l:15483704-15492959 P04323 4.51e-57 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14194 FUN_018944 4 0 0 16 0 NA NA NA NA NA NA NA 14195 FUN_018945 0 0 0 10 33 NA NA NA NA NA NA NA 14196 FUN_018946 0 0 0 46 0 NA NA NA NA NA NA NA 14197 FUN_030699 12 0 0 0 0 NA NA NA NA NA NA NA 14198 FUN_030692 24 0 4 0 8 NA NA NA NA NA NA NA 14199 FUN_030693 16 0 32 28 16 NA NA NA NA NA NA NA 14200 FUN_030690 9 0 0 25 0 NA NA NA NA NA NA NA 14201 FUN_030691 26 0 0 42 6 NA NA NA NA NA NA NA 14202 FUN_030696 57 42 81 134 186 NA NA NA NA NA NA NA 14203 FUN_030697 6 0 0 15 0 NA NA NA NA NA NA NA 14204 FUN_030695 6 0 0 0 7 NA NA NA NA NA NA NA 14205 FUN_038069 2263 3690 1099 455 1736 NA NA NA NA NA NA NA 14206 FUN_038068 324 536 177 214 280 ptg000027l:2046797-2050993 Q5HZH2 1.35e-51 18S rRNA aminocarboxypropyltransferase (EC 2.5.1.-) (20S S rRNA accumulation protein 3 homolog) Mus musculus (Mouse) enzyme-directed rRNA pseudouridine synthesis [GO:0000455]; maturation of SSU-rRNA [GO:0030490] GO:0000455; GO:0005737; GO:0016740; GO:0030490; GO:0106388; GO:1904047 14207 FUN_035267 4441 3863 1979 3545 3340 NA NA NA NA NA NA NA 14208 FUN_038061 437 281 160 181 102 ptg000027l:1964091-1965212 Q70CQ4 4.73e-38 Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005634; GO:0006511; GO:0016579 14209 FUN_038060 1497 1012 458 862 584 ptg000027l:1953408-1962906 Q70CQ4 4.44e-36 Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005634; GO:0006511; GO:0016579 14210 FUN_038060 1497 1012 458 862 584 ptg000027l:1953408-1962906 Q70CQ4 7.66e-26 Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.4.19.12) (Deubiquitinating enzyme 31) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004843; GO:0005634; GO:0006511; GO:0016579 14211 FUN_038063 2370 785 1641 1425 2130 NA NA NA NA NA NA NA 14212 FUN_038062 3729 5115 3860 3833 1956 NA NA NA NA NA NA NA 14213 FUN_038065 555 94 217 381 241 NA NA NA NA NA NA NA 14214 FUN_038064 2288 2034 784 949 1159 NA NA NA NA NA NA NA 14215 FUN_038067 22938 32482 14972 14923 14691 NA NA NA NA NA NA NA 14216 FUN_038066 69 33 59 63 39 ptg000027l:2020796-2024511 O43184 8.57e-121 Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha) Homo sapiens (Human) cell adhesion [GO:0007155]; myoblast fusion [GO:0007520]; positive regulation of angiogenesis [GO:0045766]; proteolysis [GO:0006508] GO:0004222; GO:0005576; GO:0005654; GO:0005886; GO:0006508; GO:0007155; GO:0007520; GO:0008237; GO:0017124; GO:0045766; GO:0046872 14217 FUN_036939 0 0 8 0 52 ptg000026l:3593288-3602867 P42262 6.14e-30 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249] GO:0001540; GO:0004970; GO:0004971; GO:0005789; GO:0005886; GO:0007165; GO:0007268; GO:0009897; GO:0014069; GO:0015276; GO:0030425; GO:0030666; GO:0032279; GO:0032281; GO:0035235; GO:0035249; GO:0038023; GO:0043025; GO:0043197; GO:0060076; GO:0098794; GO:0098839; GO:0098843 14218 FUN_036938 5 0 7 9 0 NA NA NA NA NA NA NA 14219 FUN_036934 2216 430 826 1444 1212 NA NA NA NA NA NA NA 14220 FUN_036937 42 50 30 56 18 NA NA NA NA NA NA NA 14221 FUN_036936 0 0 0 10 0 ptg000026l:3583306-3586200 P42262 2.88e-25 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; ionotropic glutamate receptor signaling pathway [GO:0035235]; signal transduction [GO:0007165]; synaptic transmission, glutamatergic [GO:0035249] GO:0001540; GO:0004970; GO:0004971; GO:0005789; GO:0005886; GO:0007165; GO:0007268; GO:0009897; GO:0014069; GO:0015276; GO:0030425; GO:0030666; GO:0032279; GO:0032281; GO:0035235; GO:0035249; GO:0038023; GO:0043025; GO:0043197; GO:0060076; GO:0098794; GO:0098839; GO:0098843 14222 FUN_036931 86 79 83 95 17 NA NA NA NA NA NA NA 14223 FUN_036930 0 0 0 0 89 NA NA NA NA NA NA NA 14224 FUN_036933 0 13 4 2 39 NA NA NA NA NA NA NA 14225 FUN_036932 121 178 163 130 43 NA NA NA NA NA NA NA 14226 FUN_030528 1 0 0 1 43 NA NA NA NA NA NA NA 14227 FUN_030529 0 0 0 0 20 ptg000023l:11224382-11225849 P35067 1.23e-79 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14228 FUN_030520 26 0 29 3 179 NA NA NA NA NA NA NA 14229 FUN_030522 10 0 0 0 0 NA NA NA NA NA NA NA 14230 FUN_023322 2828 1712 1578 2049 2112 NA NA NA NA NA NA NA 14231 FUN_026131 0 0 0 40 0 NA NA NA NA NA NA NA 14232 FUN_023320 1627 487 893 1518 1578 NA NA NA NA NA NA NA 14233 FUN_026133 0 216 71 63 5 NA NA NA NA NA NA NA 14234 FUN_020110 0 0 0 0 26 NA NA NA NA NA NA NA 14235 FUN_023326 44 96 14 77 98 NA NA NA NA NA NA NA 14236 FUN_023324 2643 1490 1097 1284 1359 NA NA NA NA NA NA NA 14237 FUN_025448 0 0 11 17 0 NA NA NA NA NA NA NA 14238 FUN_001600 0 0 0 0 11 NA NA NA NA NA NA NA 14239 FUN_001603 1642 1334 814 1610 1254 NA NA NA NA NA NA NA 14240 FUN_007293 0 0 15 4 84 NA NA NA NA NA NA NA 14241 FUN_001609 80 110 8 60 58 NA NA NA NA NA NA NA 14242 FUN_001608 373 209 177 253 164 NA NA NA NA NA NA NA 14243 FUN_036203 0 0 10 0 23 NA NA NA NA NA NA NA 14244 FUN_036202 264 633 98 642 284 NA NA NA NA NA NA NA 14245 FUN_036201 184 1847 324 127 623 NA NA NA NA NA NA NA 14246 FUN_036200 42 65 0 66 144 NA NA NA NA NA NA NA 14247 FUN_036207 2849 1381 1368 963 1147 NA NA NA NA NA NA NA 14248 FUN_036206 108 74 81 110 239 NA NA NA NA NA NA NA 14249 FUN_036205 709 577 475 758 692 ptg000025l:16500022-16512101 O88554 1.07e-22 Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-) Mus musculus (Mouse) base-excision repair [GO:0006284]; decidualization [GO:0046697]; DNA ADP-ribosylation [GO:0030592]; DNA repair [GO:0006281]; double-strand break repair [GO:0006302]; extrinsic apoptotic signaling pathway [GO:0097191]; histone modification [GO:0016570]; negative regulation of neuron death [GO:1901215]; positive regulation of cell growth involved in cardiac muscle cell development [GO:0061051]; protein auto-ADP-ribosylation [GO:0070213]; protein poly-ADP-ribosylation [GO:0070212] GO:0003682; GO:0003684; GO:0003950; GO:0005634; GO:0005654; GO:0005730; GO:0006281; GO:0006284; GO:0006302; GO:0016570; GO:0016779; GO:0030592; GO:0031491; GO:0046697; GO:0061051; GO:0070212; GO:0070213; GO:0072572; GO:0090734; GO:0097191; GO:0140294; GO:0140805; GO:0140806; GO:0140807; GO:1901215; GO:1990404 14250 FUN_036204 3113 1404 2008 2210 2569 ptg000025l:16486530-16498566 Q5RKH1 7.32e-31 Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre-mRNA-processing factor 4 homolog) Rattus norvegicus (Rat) mRNA cis splicing, via spliceosome [GO:0045292]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0005694; GO:0006468; GO:0016607; GO:0045292; GO:0071013; GO:0106310 14251 FUN_036209 0 11 1 1 6 NA NA NA NA NA NA NA 14252 FUN_036208 2414 1426 1032 2345 2242 NA NA NA NA NA NA NA 14253 FUN_027469 6 2 15 2 38 NA NA NA NA NA NA NA 14254 FUN_027468 74 0 6 0 0 NA NA NA NA NA NA NA 14255 FUN_027461 3 0 0 6 0 NA NA NA NA NA NA NA 14256 FUN_027465 39 0 14 0 0 NA NA NA NA NA NA NA 14257 FUN_027467 70 115 41 31 63 NA NA NA NA NA NA NA 14258 FUN_027466 42 0 16 0 14 NA NA NA NA NA NA NA 14259 FUN_018394 1163 458 886 976 380 NA NA NA NA NA NA NA 14260 FUN_026496 150 8 37 0 57 NA NA NA NA NA NA NA 14261 FUN_018390 300 60 197 219 8 NA NA NA NA NA NA NA 14262 FUN_018392 1206 1245 609 1464 1000 ptg000012l:8769357-8780752 F1MMV1 2.54e-30 EF-hand domain-containing family member B (Cilia- and flagella-associated protein 21) Bos taurus (Bovine) calcium ion transport [GO:0006816]; negative regulation of protein binding [GO:0032091]; regulation of calcineurin-NFAT signaling cascade [GO:0070884]; regulation of store-operated calcium entry [GO:2001256] GO:0005879; GO:0006816; GO:0032091; GO:0061891; GO:0070884; GO:2001256 14263 FUN_016748 32 54 0 14 5 ptg000011l:6935351-6951707 Q96AY4 1.85e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14264 FUN_016748 32 54 0 14 5 ptg000011l:6935351-6951707 Q96AY4 8.19e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14265 FUN_016748 32 54 0 14 5 ptg000011l:6935351-6951707 Q96AY4 7.6e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14266 FUN_016748 32 54 0 14 5 ptg000011l:6935351-6951707 Q96AY4 2.99e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14267 FUN_016748 32 54 0 14 5 ptg000011l:6935351-6951707 Q96AY4 2.34e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14268 FUN_016748 32 54 0 14 5 ptg000011l:6935351-6951707 Q96AY4 1.49e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14269 FUN_034240 1481 617 848 1982 963 NA NA NA NA NA NA NA 14270 FUN_032478 658 450 366 478 519 NA NA NA NA NA NA NA 14271 FUN_026495 48 117 16 70 28 NA NA NA NA NA NA NA 14272 FUN_032479 89 64 33 72 95 NA NA NA NA NA NA NA 14273 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 2.12e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14274 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 3.28e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14275 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.69e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14276 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 8.33e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14277 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 2.05e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14278 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 6.48e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14279 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 3.42e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14280 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.49e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14281 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 2.34e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14282 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 2.34e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14283 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 2.4e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14284 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 2.4e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14285 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 3.8e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14286 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 3.8e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14287 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 9.46e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14288 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.02e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14289 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 4.11e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14290 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 3.15e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14291 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.11e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14292 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 3.47e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14293 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.67e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14294 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.67e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14295 FUN_033187 116 42 16 71 89 ptg000023l:40817287-40822193 Q96AY4 1.77e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14296 FUN_033186 12 24 0 31 56 NA NA NA NA NA NA NA 14297 FUN_033183 0 62 44 38 43 NA NA NA NA NA NA NA 14298 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14299 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14300 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14301 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 1.04e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14302 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 9.02e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14303 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 6.68e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14304 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 1.15e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14305 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 1.75e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14306 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 2.49e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14307 FUN_033182 1 17 0 35 1 ptg000023l:40781509-40785173 Q96AY4 4.46e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14308 FUN_033181 21 18 0 0 63 NA NA NA NA NA NA NA 14309 FUN_033180 0 0 14 0 58 NA NA NA NA NA NA NA 14310 FUN_016749 0 16 0 0 47 NA NA NA NA NA NA NA 14311 FUN_033189 19 35 3 181 24 ptg000023l:40837993-40843172 Q96AY4 2.16e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14312 FUN_033189 19 35 3 181 24 ptg000023l:40837993-40843172 Q96AY4 2.14e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14313 FUN_033189 19 35 3 181 24 ptg000023l:40837993-40843172 Q96AY4 4.49e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14314 FUN_033189 19 35 3 181 24 ptg000023l:40837993-40843172 Q96AY4 1.1e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14315 FUN_033189 19 35 3 181 24 ptg000023l:40837993-40843172 Q96AY4 2.13e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14316 FUN_033189 19 35 3 181 24 ptg000023l:40837993-40843172 Q96AY4 3.49e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14317 FUN_033188 0 0 0 23 23 NA NA NA NA NA NA NA 14318 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 0 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14319 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 2.42e-108 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14320 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 2.76e-102 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14321 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 1.95e-101 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14322 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 1.06e-99 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14323 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 2.51e-96 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14324 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 4.04e-74 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14325 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 4.1e-64 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14326 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 8.54e-64 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14327 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 6.47e-45 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14328 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 7.89e-42 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14329 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 1.31e-37 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14330 FUN_006653 373 235 136 209 183 ptg000001l:15192565-15198362 Q24292 1.02e-32 Protein dachsous (Adherin) Drosophila melanogaster (Fruit fly) cell-cell adhesion [GO:0098609]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; imaginal disc morphogenesis [GO:0007560]; negative regulation of hippo signaling [GO:0035331]; positive regulation of hippo signaling [GO:0035332]; protein localization involved in establishment of planar polarity [GO:0090251] GO:0001736; GO:0005509; GO:0005886; GO:0007156; GO:0007560; GO:0016327; GO:0035331; GO:0035332; GO:0042067; GO:0070161; GO:0090251; GO:0098609 14331 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 0 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14332 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 2.13e-119 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14333 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 2.9e-117 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14334 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 3.79e-116 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14335 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 5.56e-104 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14336 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 1.06e-95 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14337 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 8.91e-95 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14338 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 9.8e-68 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14339 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 1.04e-58 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14340 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 5.48e-27 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14341 FUN_006652 3160 1368 1472 2266 2086 ptg000001l:15184182-15191498 Q6V1P9 4.7e-22 Protocadherin-23 (Cadherin-27) (Cadherin-like protein CDHJ) (Cadherin-like protein VR8) (Protein dachsous homolog 2) (Protocadherin PCDHJ) Homo sapiens (Human) condensed mesenchymal cell proliferation [GO:0072137]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; nephron development [GO:0072006] GO:0005509; GO:0005886; GO:0007156; GO:0072006; GO:0072137 14342 FUN_008235 387 267 145 260 281 ptg000002l:9540769-9543886 P46718 3.12e-43 Programmed cell death protein 2 (Zinc finger protein Rp-8) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of hematopoietic stem cell proliferation [GO:1902035]; regulation of hematopoietic progenitor cell differentiation [GO:1901532] GO:0003677; GO:0005634; GO:0005737; GO:0006915; GO:0006919; GO:0019899; GO:0043065; GO:0046872; GO:1901532; GO:1902035 14343 FUN_006650 611 194 121 425 429 ptg000001l:15153983-15161389 Q9QYB2 3.12e-27 Dachshund homolog 1 (Dach1) Mus musculus (Mouse) development of primary female sexual characteristics [GO:0046545]; epithelial cell proliferation [GO:0050673]; negative regulation of cell migration [GO:0030336]; negative regulation of cell proliferation involved in contact inhibition [GO:0060244]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of transcription by competitive promoter binding [GO:0010944]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of nuclear cell cycle DNA replication [GO:0033262]; regulation of transcription by RNA polymerase II [GO:0006357]; respiratory gaseous exchange by respiratory system [GO:0007585]; suckling behavior [GO:0001967]; type B pancreatic cell proliferation [GO:0044342] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001967; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005794; GO:0005829; GO:0006355; GO:0006357; GO:0007585; GO:0010944; GO:0016607; GO:0030336; GO:0033262; GO:0044342; GO:0045892; GO:0046545; GO:0048147; GO:0050673; GO:0060244; GO:2000279 14344 FUN_008233 0 0 0 0 9 ptg000002l:9525649-9527084 Q90964 7.1e-34 Forkhead box protein G1 (FoxG1) (Brain factor 1) (BF-1) (BF1) (cBF-1) (CEQ 3-1) (Forkhead-related protein FKHL1) (N-62-5) (Proto-oncogene C-QIN) Gallus gallus (Chicken) axon midline choice point recognition [GO:0016199]; dorsal/ventral pattern formation [GO:0009953]; inner ear morphogenesis [GO:0042472]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; positive regulation of cell cycle [GO:0045787]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron differentiation [GO:0045666]; pyramidal neuron migration to cerebral cortex [GO:0021852]; regulation of mitotic cell cycle [GO:0007346]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0002052; GO:0003700; GO:0005634; GO:0006357; GO:0007346; GO:0007405; GO:0009953; GO:0016199; GO:0021852; GO:0042472; GO:0045665; GO:0045666; GO:0045787; GO:0048664; GO:1990837 14345 FUN_006656 2432 1308 985 2042 1387 ptg000001l:15238995-15246021 A7MB46 1.3e-45 Protocadherin-18 Bos taurus (Bovine) brain development [GO:0007420]; cell adhesion [GO:0007155]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007155; GO:0007156; GO:0007420 14346 FUN_008231 22 47 10 95 33 NA NA NA NA NA NA NA 14347 FUN_008230 44 26 0 24 47 NA NA NA NA NA NA NA 14348 FUN_032580 902 1239 591 1260 1234 NA NA NA NA NA NA NA 14349 FUN_032581 2101 2460 1413 2182 1670 NA NA NA NA NA NA NA 14350 FUN_032583 431 225 232 315 324 NA NA NA NA NA NA NA 14351 FUN_032584 3407 4082 2474 2472 1722 NA NA NA NA NA NA NA 14352 FUN_032585 79 38 168 30 572 NA NA NA NA NA NA NA 14353 FUN_032586 31 0 144 17 872 NA NA NA NA NA NA NA 14354 FUN_008238 1017 539 762 1320 1000 NA NA NA NA NA NA NA 14355 FUN_042990 242 410 163 255 260 NA NA NA NA NA NA NA 14356 FUN_042991 8008 6122 5185 8258 6262 ptg000047l:2788913-2792206 Q6IP82 5.84e-28 Calumenin Xenopus laevis (African clawed frog) NA GO:0005509; GO:0005576; GO:0005789; GO:0005794; GO:0033018; GO:0042470 14357 FUN_042992 23 0 87 33 21 NA NA NA NA NA NA NA 14358 FUN_042993 1296 588 526 1046 984 ptg000047l:2798636-2809833 Q96AY4 6.64e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14359 FUN_042994 949 982 1384 626 905 NA NA NA NA NA NA NA 14360 FUN_042995 0 0 0 0 14 NA NA NA NA NA NA NA 14361 FUN_042996 0 11 0 0 0 NA NA NA NA NA NA NA 14362 FUN_042997 1205 1110 680 805 764 NA NA NA NA NA NA NA 14363 FUN_042998 51722 66115 25826 33706 22835 ptg000047l:2824740-2829038 G1SIT5 1.84e-24 NA NA NA NA 14364 FUN_003512 5 0 13 0 55 NA NA NA NA NA NA NA 14365 FUN_003510 0 0 14 0 11 NA NA NA NA NA NA NA 14366 FUN_003517 2 0 112 0 3 NA NA NA NA NA NA NA 14367 FUN_003516 0 0 0 0 13 NA NA NA NA NA NA NA 14368 FUN_003514 0 0 31 107 58 NA NA NA NA NA NA NA 14369 FUN_010207 19 0 0 64 46 NA NA NA NA NA NA NA 14370 FUN_004724 26 12 17 92 68 NA NA NA NA NA NA NA 14371 FUN_004726 909 795 421 65 87 NA NA NA NA NA NA NA 14372 FUN_004729 224 273 91 84 156 NA NA NA NA NA NA NA 14373 FUN_004728 218 139 147 32 38 NA NA NA NA NA NA NA 14374 FUN_015126 0 0 0 7 9 NA NA NA NA NA NA NA 14375 FUN_041872 1102 645 602 635 561 NA NA NA NA NA NA NA 14376 FUN_041873 4722 4030 2604 4298 2901 NA NA NA NA NA NA NA 14377 FUN_041870 993 421 233 673 416 NA NA NA NA NA NA NA 14378 FUN_041871 11 28 4 13 12 ptg000035l:8464159-8465677 Q9IB89 8.22e-83 Zinc finger protein ZIC 5 (XZic5) (XlZic5) (Zinc finger protein of the cerebellum 5) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 14379 FUN_041876 90 0 288 0 43 NA NA NA NA NA NA NA 14380 FUN_041877 4466 2885 1908 3304 3515 NA NA NA NA NA NA NA 14381 FUN_041874 772 658 480 873 609 ptg000035l:8484240-8497238 P49959 1.14e-30 Double-strand break repair protein MRE11 (EC 3.1.-.-) (Double-strand break repair protein MRE11A) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A) Homo sapiens (Human) cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; DNA double-strand break processing [GO:0000729]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA strand resection involved in replication fork processing [GO:0110025]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via nonhomologous end joining [GO:0006303]; homologous chromosome pairing at meiosis [GO:0007129]; homologous recombination [GO:0035825]; meiotic DNA double-strand break formation [GO:0042138]; mitochondrial double-strand break repair via homologous recombination [GO:0097552]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic G2/M transition checkpoint [GO:0044818]; mitotic intra-S DNA damage checkpoint signaling [GO:0031573]; negative regulation of apoptotic process [GO:0043066]; positive regulation of kinase activity [GO:0033674]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of telomere maintenance [GO:0032206]; reciprocal meiotic recombination [GO:0007131]; regulation of mitotic recombination [GO:0000019]; sister chromatid cohesion [GO:0007062]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004]; telomeric 3' overhang formation [GO:0031860] GO:0000014; GO:0000019; GO:0000723; GO:0000724; GO:0000729; GO:0000781; GO:0003690; GO:0004518; GO:0004520; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005829; GO:0006281; GO:0006302; GO:0006303; GO:0006310; GO:0006974; GO:0007004; GO:0007062; GO:0007095; GO:0007129; GO:0007131; GO:0008022; GO:0008283; GO:0008296; GO:0008408; GO:0008409; GO:0016605; GO:0030145; GO:0030870; GO:0031573; GO:0031860; GO:0031954; GO:0032206; GO:0032508; GO:0033674; GO:0035825; GO:0035861; GO:0042138; GO:0042802; GO:0043066; GO:0044818; GO:0045296; GO:0070533; GO:0097552; GO:0098687; GO:0110025 14382 FUN_041875 2801 2329 1354 2654 2107 ptg000035l:8497867-8502390 Q5YJC2 4.05e-32 Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) Spermophilus citellus (European suslik) (Citellus citellus) cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; epithelial to mesenchymal transition [GO:0001837]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of developmental process [GO:0051093]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of cilium assembly [GO:0045724]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cilium [GO:1903566]; protein phosphorylation [GO:0006468]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055] GO:0001837; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0005977; GO:0006468; GO:0007399; GO:0007623; GO:0010508; GO:0016020; GO:0016055; GO:0016301; GO:0018105; GO:0032092; GO:0032886; GO:0036016; GO:0045724; GO:0050321; GO:0051093; GO:0070885; GO:0097192; GO:0106310; GO:1901030; GO:1902042; GO:1903566 14383 FUN_041875 2801 2329 1354 2654 2107 ptg000035l:8497867-8502390 Q5YJC2 1.88e-25 Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1) Spermophilus citellus (European suslik) (Citellus citellus) cellular response to interleukin-3 [GO:0036016]; circadian rhythm [GO:0007623]; epithelial to mesenchymal transition [GO:0001837]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; glycogen metabolic process [GO:0005977]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of developmental process [GO:0051093]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; nervous system development [GO:0007399]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of autophagy [GO:0010508]; positive regulation of cilium assembly [GO:0045724]; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901030]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cilium [GO:1903566]; protein phosphorylation [GO:0006468]; regulation of microtubule-based process [GO:0032886]; Wnt signaling pathway [GO:0016055] GO:0001837; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005886; GO:0005977; GO:0006468; GO:0007399; GO:0007623; GO:0010508; GO:0016020; GO:0016055; GO:0016301; GO:0018105; GO:0032092; GO:0032886; GO:0036016; GO:0045724; GO:0050321; GO:0051093; GO:0070885; GO:0097192; GO:0106310; GO:1901030; GO:1902042; GO:1903566 14384 FUN_041878 310 299 159 300 187 NA NA NA NA NA NA NA 14385 FUN_041879 310 280 283 318 200 NA NA NA NA NA NA NA 14386 FUN_034381 611 555 437 513 444 NA NA NA NA NA NA NA 14387 FUN_011152 0 0 33 0 30 NA NA NA NA NA NA NA 14388 FUN_011153 3 0 24 0 241 NA NA NA NA NA NA NA 14389 FUN_011158 0 0 0 0 7 NA NA NA NA NA NA NA 14390 FUN_040835 3 0 2 12 2 NA NA NA NA NA NA NA 14391 FUN_040839 5 0 39 0 76 NA NA NA NA NA NA NA 14392 FUN_040838 0 0 8 0 63 NA NA NA NA NA NA NA 14393 FUN_002397 383 55 125 312 288 NA NA NA NA NA NA NA 14394 FUN_002394 0 0 7 0 52 NA NA NA NA NA NA NA 14395 FUN_002395 0 148 0 555 0 NA NA NA NA NA NA NA 14396 FUN_020919 0 30 23 0 0 NA NA NA NA NA NA NA 14397 FUN_000899 2156 2023 1317 1793 1129 NA NA NA NA NA NA NA 14398 FUN_000898 559 206 297 213 217 ntLink_6:5823168-5826268 O43903 6.69e-45 Growth arrest-specific protein 2 (GAS-2) Homo sapiens (Human) actin crosslink formation [GO:0051764]; antral ovarian follicle growth [GO:0001547]; apoptotic process [GO:0006915]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; initiation of primordial ovarian follicle growth [GO:0001544]; ovulation [GO:0030728]; regulation of cell cycle [GO:0051726]; regulation of cell shape [GO:0008360]; regulation of Notch signaling pathway [GO:0008593] GO:0001544; GO:0001547; GO:0005829; GO:0005884; GO:0006915; GO:0007049; GO:0008017; GO:0008093; GO:0008360; GO:0008593; GO:0016020; GO:0030728; GO:0051015; GO:0051726; GO:0051764; GO:0071711 14399 FUN_000893 87 64 30 326 147 NA NA NA NA NA NA NA 14400 FUN_000892 177 146 36 93 138 NA NA NA NA NA NA NA 14401 FUN_000891 1779 1779 608 1031 1196 ntLink_6:5743473-5751461 P47937 1.66e-28 Neuromedin-K receptor (NKR) (NK-3 receptor) (NK-3R) (Neurokinin B receptor) (Tachykinin receptor 3) Mus musculus (Mouse) aging [GO:0007568]; hyperosmotic salinity response [GO:0042538]; positive regulation of blood pressure [GO:0045777]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of heart rate [GO:0010460]; positive regulation of uterine smooth muscle contraction [GO:0070474]; regulation of dopamine metabolic process [GO:0042053]; regulation of feeding behavior [GO:0060259]; response to cocaine [GO:0042220]; response to estradiol [GO:0032355]; response to morphine [GO:0043278] GO:0004995; GO:0005634; GO:0005737; GO:0005886; GO:0007568; GO:0010460; GO:0016020; GO:0032355; GO:0032590; GO:0032809; GO:0042053; GO:0042220; GO:0042538; GO:0043278; GO:0045777; GO:0060259; GO:0070474; GO:0097225; GO:1902093 14402 FUN_000897 276 80 35 159 91 NA NA NA NA NA NA NA 14403 FUN_000896 3578 2393 2843 3760 2039 NA NA NA NA NA NA NA 14404 FUN_000895 1213 1377 832 1121 1232 ntLink_6:5778589-5779462 Q96K80 1.64e-34 Zinc finger CCCH domain-containing protein 10 Homo sapiens (Human) negative regulation of miRNA maturation [GO:1903799]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003723; GO:0005654; GO:0005737; GO:0010608; GO:0035198; GO:0046872; GO:1903799 14405 FUN_000894 166 199 119 618 379 ntLink_6:5773088-5777017 Q7SXV2 2.57e-26 Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2 homolog) (AE-binding protein 2 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0006325; GO:0006357; GO:0035098; GO:0046872 14406 FUN_029434 7235 8038 3105 4492 2610 NA NA NA NA NA NA NA 14407 FUN_029435 46 0 25 27 23 ptg000023l:1857625-1859416 O93403 7.88e-26 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 14408 FUN_029436 26 8 27 72 13 ptg000023l:1869135-1870461 O93403 8.18e-28 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 14409 FUN_029437 75 103 85 169 62 ptg000023l:1876285-1881129 O93403 7.81e-25 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Nervous system involved sulfotransferase) Tetronarce californica (Pacific electric ray) (Torpedo californica) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0005975; GO:0008459; GO:0030206 14410 FUN_029430 76 204 118 271 70 NA NA NA NA NA NA NA 14411 FUN_029431 63 213 96 279 64 NA NA NA NA NA NA NA 14412 FUN_029432 0 0 0 11 12 NA NA NA NA NA NA NA 14413 FUN_029433 233 11 0 223 360 NA NA NA NA NA NA NA 14414 FUN_029438 1024 507 473 557 704 ptg000023l:1899273-1904550 Q8IZF0 0 Sodium leak channel NALCN (CanIon) (Sodium leak channel non-selective protein) (Voltage gated channel-like protein 1) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; ion transmembrane transport [GO:0034220]; positive regulation of synaptic transmission, cholinergic [GO:0032224]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of resting membrane potential [GO:0060075]; sodium ion transmembrane transport [GO:0035725] GO:0005244; GO:0005248; GO:0005261; GO:0005272; GO:0005886; GO:0022840; GO:0032224; GO:0032230; GO:0034220; GO:0034765; GO:0035725; GO:0060075; GO:0070588; GO:0071805 14415 FUN_029439 1059 299 329 819 479 ptg000023l:1904991-1906248 P18298 0 S-adenosylmethionine synthase isoform type-2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2) (Methionine adenosyltransferase II) (MAT-II) Rattus norvegicus (Rat) cellular response to leukemia inhibitory factor [GO:1990830]; circadian rhythm [GO:0007623]; one-carbon metabolic process [GO:0006730]; protein heterooligomerization [GO:0051291]; protein hexamerization [GO:0034214]; response to cAMP [GO:0051591]; response to hormone [GO:0009725]; response to light stimulus [GO:0009416]; response to xenobiotic stimulus [GO:0009410]; S-adenosylmethionine biosynthetic process [GO:0006556] GO:0004478; GO:0005524; GO:0005829; GO:0006556; GO:0006730; GO:0007623; GO:0009410; GO:0009416; GO:0009725; GO:0016597; GO:0034214; GO:0036094; GO:0042802; GO:0046872; GO:0048269; GO:0051291; GO:0051591; GO:1990830 14416 FUN_020942 0 0 27 0 146 NA NA NA NA NA NA NA 14417 FUN_043568 1949 1805 1964 2550 1426 NA NA NA NA NA NA NA 14418 FUN_043569 1350 1071 1353 1586 1450 NA NA NA NA NA NA NA 14419 FUN_022160 0 0 6 48 13 ptg000016l:5837178-5840963 B8UU78 4.46e-168 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14420 FUN_022160 0 0 6 48 13 ptg000016l:5837178-5840963 B8UU78 4.53e-28 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 14421 FUN_043562 1133 869 389 733 813 ptg000047l:9922234-9927269 Q6DHJ3 1.66e-71 Cholesterol 7-desaturase nvd (EC 1.14.19.21) (Protein neverland) (Nvd protein) (nvd-Dr) Danio rerio (Zebrafish) (Brachydanio rerio) cholesterol metabolic process [GO:0008203] GO:0005737; GO:0008203; GO:0016020; GO:0016491; GO:0046872; GO:0051537 14422 FUN_043563 15497 12449 6313 13139 12571 ptg000047l:9930996-9933407 P53812 6.77e-90 Phosphatidylinositol transfer protein beta isoform (PI-TP-beta) (PtdIns transfer protein beta) (PtdInsTP beta) Rattus norvegicus (Rat) in utero embryonic development [GO:0001701]; phospholipid transport [GO:0015914]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0001701; GO:0005737; GO:0005789; GO:0005794; GO:0006890; GO:0008525; GO:0008526; GO:0015914; GO:0031210; GO:0035091; GO:0120019; GO:0140338 14423 FUN_043560 8973 7087 4485 7495 6771 ptg000047l:9901597-9909479 Q27433 5.22e-24 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 14424 FUN_043561 6558 3929 1732 2645 3394 ptg000047l:9913035-9919722 Q27433 1.3e-22 Mechanosensory protein 2 Caenorhabditis elegans detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; mechanosensory behavior [GO:0007638]; positive regulation of detection of mechanical stimulus involved in sensory perception of touch [GO:1905789]; positive regulation of mechanosensory behavior [GO:1905792]; potassium ion transport [GO:0006813]; response to mechanical stimulus [GO:0009612] GO:0005272; GO:0005886; GO:0006813; GO:0007638; GO:0009612; GO:0015485; GO:0032589; GO:0043005; GO:0050976; GO:1905789; GO:1905792 14425 FUN_043566 245 258 96 114 302 NA NA NA NA NA NA NA 14426 FUN_043567 1003 528 424 744 671 NA NA NA NA NA NA NA 14427 FUN_043564 8429 11277 3519 5276 5767 NA NA NA NA NA NA NA 14428 FUN_043565 2161 1310 959 1580 1916 NA NA NA NA NA NA NA 14429 FUN_008125 1156 1568 405 695 1102 NA NA NA NA NA NA NA 14430 FUN_016319 17 95 24 92 21 NA NA NA NA NA NA NA 14431 FUN_016318 2448 1594 1697 2644 1932 NA NA NA NA NA NA NA 14432 FUN_016317 1887 1839 1327 1344 997 NA NA NA NA NA NA NA 14433 FUN_016316 3645 3437 1828 2609 2169 NA NA NA NA NA NA NA 14434 FUN_016315 1395 1340 88 402 301 NA NA NA NA NA NA NA 14435 FUN_016314 4541 5033 4355 5250 4384 ptg000011l:1502879-1507256 P81999 1.79e-24 DnaJ homolog subfamily B member 11 (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) Canis lupus familiaris (Dog) (Canis familiaris) protein folding [GO:0006457]; protein maturation [GO:0051604] GO:0005788; GO:0006457; GO:0051082; GO:0051604 14436 FUN_016313 232 115 167 157 417 ptg000011l:1497231-1500987 B0S5Y3 1.99e-61 Solute carrier family 52, riboflavin transporter, member 3-A (Riboflavin transporter 2-A) (RFT2-A) Danio rerio (Zebrafish) (Brachydanio rerio) riboflavin transport [GO:0032218] GO:0005886; GO:0032217; GO:0032218 14437 FUN_016312 1273 943 565 1640 1260 NA NA NA NA NA NA NA 14438 FUN_016311 2631 1614 1313 3233 1887 ptg000011l:1492791-1494319 Q801F8 2.83e-23 Doublesex- and mab-3-related transcription factor 1 Oryzias latipes (Japanese rice fish) (Japanese killifish) germ cell development [GO:0007281]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007281; GO:0007548; GO:0046872 14439 FUN_016310 0 24 0 67 34 NA NA NA NA NA NA NA 14440 FUN_013792 0 6 0 0 13 NA NA NA NA NA NA NA 14441 FUN_013793 56 9 0 6 5 NA NA NA NA NA NA NA 14442 FUN_013794 34 0 0 0 58 NA NA NA NA NA NA NA 14443 FUN_013797 7 294 441 56 457 NA NA NA NA NA NA NA 14444 FUN_013799 1 6 0 1 13 NA NA NA NA NA NA NA 14445 FUN_015656 0 0 12 0 0 NA NA NA NA NA NA NA 14446 FUN_015654 10 65 0 0 44 NA NA NA NA NA NA NA 14447 FUN_015653 0 0 0 99 0 NA NA NA NA NA NA NA 14448 FUN_015652 0 0 0 0 8 NA NA NA NA NA NA NA 14449 FUN_015651 146 72 0 68 121 NA NA NA NA NA NA NA 14450 FUN_015650 0 0 7 0 10 NA NA NA NA NA NA NA 14451 FUN_023179 23225 41414 22975 26661 20817 ptg000017l:4608234-4610589 P47832 7.18e-22 60S ribosomal protein L26 Gallus gallus (Chicken) cytoplasmic translation [GO:0002181]; ribosomal large subunit biogenesis [GO:0042273] GO:0002181; GO:0003723; GO:0003735; GO:0022625; GO:0042273 14452 FUN_023178 7000 4419 3289 5098 3866 NA NA NA NA NA NA NA 14453 FUN_023173 1019 492 291 1012 1106 ptg000017l:4526854-4539163 O93309 3.33e-23 Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) Xenopus laevis (African clawed frog) cell division [GO:0051301]; chromosome organization [GO:0051276]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; regulation of DNA replication [GO:0006275] GO:0000775; GO:0000785; GO:0005524; GO:0005634; GO:0006275; GO:0006281; GO:0016887; GO:0030893; GO:0051276; GO:0051301; GO:0051321 14454 FUN_023172 340 554 152 362 272 NA NA NA NA NA NA NA 14455 FUN_023171 210 16 177 646 175 NA NA NA NA NA NA NA 14456 FUN_023170 5112 4284 3447 5936 3449 NA NA NA NA NA NA NA 14457 FUN_023177 1311 598 491 491 684 NA NA NA NA NA NA NA 14458 FUN_023176 0 0 46 14 36 NA NA NA NA NA NA NA 14459 FUN_023175 283 353 135 174 139 NA NA NA NA NA NA NA 14460 FUN_023174 503 266 240 473 414 NA NA NA NA NA NA NA 14461 FUN_008121 2249 1462 1163 2118 1648 ptg000002l:8244484-8256892 Q5TCY1 4.48e-24 Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase) Homo sapiens (Human) learning or memory [GO:0007611]; negative regulation of gene expression [GO:0010629]; negative regulation of protein binding [GO:0032091]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of astrocyte activation [GO:0061890]; positive regulation of cyclin-dependent protein kinase activity [GO:1904031]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of gene expression [GO:0010628]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of protein polymerization [GO:0032273]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; substantia nigra development [GO:0021762] GO:0004674; GO:0004713; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005875; GO:0006468; GO:0007165; GO:0007611; GO:0010628; GO:0010629; GO:0018105; GO:0018107; GO:0018108; GO:0021762; GO:0032091; GO:0032273; GO:0043025; GO:0048156; GO:0048471; GO:0050321; GO:0061890; GO:0106310; GO:1903980; GO:1904031; GO:2001056 14462 FUN_028477 2612 718 804 1134 1069 ptg000021l:20506814-20519574 Q86NP2 4.54e-22 Negative elongation factor A Drosophila melanogaster (Fruit fly) negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244] GO:0000122; GO:0003723; GO:0005634; GO:0005694; GO:0017053; GO:0032021; GO:0034244 14463 FUN_028474 33 105 32 0 56 NA NA NA NA NA NA NA 14464 FUN_028473 8434 6885 5681 5039 3976 NA NA NA NA NA NA NA 14465 FUN_028472 476 399 263 680 169 NA NA NA NA NA NA NA 14466 FUN_041052 6 0 10 0 43 NA NA NA NA NA NA NA 14467 FUN_039779 2393 1312 1245 2414 1411 ptg000031l:68982-91215 O60658 1.51e-24 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53) Homo sapiens (Human) cAMP catabolic process [GO:0006198]; cellular response to epidermal growth factor stimulus [GO:0071364]; negative regulation of cell death [GO:0060548]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; regulation of DNA-templated transcription [GO:0006355]; signal transduction [GO:0007165] GO:0001934; GO:0004114; GO:0004115; GO:0005829; GO:0006198; GO:0006355; GO:0007165; GO:0019900; GO:0046872; GO:0047555; GO:0060548; GO:0070062; GO:0070374; GO:0071364; GO:1903206 14468 FUN_011936 189 127 48 243 68 NA NA NA NA NA NA NA 14469 FUN_011934 6688 5694 3605 5093 3338 NA NA NA NA NA NA NA 14470 FUN_011935 102 78 88 181 84 NA NA NA NA NA NA NA 14471 FUN_011932 1823 877 1517 1763 1487 NA NA NA NA NA NA NA 14472 FUN_011933 2139 1384 1224 2148 1356 ptg000008l:3254938-3289041 Q9TZM3 5.46e-31 Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) (Leucine-rich repeats, ras-like domain, kinase protein 1) (PARK8-related kinase) Caenorhabditis elegans axon extension involved in axon guidance [GO:0048846]; negative regulation of neuron death [GO:1901215]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; response to endoplasmic reticulum stress [GO:0034976]; response to oxidative stress [GO:0006979]; synaptic vesicle transport [GO:0048489] GO:0004674; GO:0005524; GO:0005525; GO:0005737; GO:0005794; GO:0006468; GO:0006979; GO:0008104; GO:0034976; GO:0043025; GO:0046872; GO:0048489; GO:0048846; GO:0106310; GO:1901215 14473 FUN_011930 183 276 123 203 203 NA NA NA NA NA NA NA 14474 FUN_011931 908 613 445 495 561 ptg000008l:3236245-3243922 Q9BWD1 3.87e-32 Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; lipid metabolic process [GO:0006629] GO:0003985; GO:0005737; GO:0005739; GO:0005829; GO:0006629; GO:0006635; GO:0070062 14475 FUN_011938 28 0 0 11 46 NA NA NA NA NA NA NA 14476 FUN_022773 4 15 1 1 1 NA NA NA NA NA NA NA 14477 FUN_039776 2632 2159 1589 1266 904 NA NA NA NA NA NA NA 14478 FUN_009113 55 106 55 22 41 ptg000004l:2853949-2862172 Q96AY4 9.91e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14479 FUN_009113 55 106 55 22 41 ptg000004l:2853949-2862172 Q96AY4 9.49e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14480 FUN_009113 55 106 55 22 41 ptg000004l:2853949-2862172 Q96AY4 1.82e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14481 FUN_009112 52 39 42 24 37 ptg000004l:2833903-2838166 Q96AY4 2.43e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14482 FUN_009112 52 39 42 24 37 ptg000004l:2833903-2838166 Q96AY4 1.35e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14483 FUN_009112 52 39 42 24 37 ptg000004l:2833903-2838166 Q96AY4 2.78e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14484 FUN_009112 52 39 42 24 37 ptg000004l:2833903-2838166 Q96AY4 1.35e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14485 FUN_009112 52 39 42 24 37 ptg000004l:2833903-2838166 Q96AY4 1.02e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14486 FUN_025637 123 63 128 63 175 NA NA NA NA NA NA NA 14487 FUN_025634 0 0 42 26 4 NA NA NA NA NA NA NA 14488 FUN_025632 257 156 155 230 186 NA NA NA NA NA NA NA 14489 FUN_025633 9 0 10 21 51 NA NA NA NA NA NA NA 14490 FUN_025630 128 106 47 406 255 NA NA NA NA NA NA NA 14491 FUN_022777 4089 1926 1654 2138 2320 NA NA NA NA NA NA NA 14492 FUN_018932 127 122 47 91 128 ptg000012l:15376982-15388167 P0CT39 1.81e-71 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 14493 FUN_008178 0 0 0 14 0 NA NA NA NA NA NA NA 14494 FUN_022774 0 12 0 0 14 NA NA NA NA NA NA NA 14495 FUN_024589 3277 1470 1356 2251 1439 NA NA NA NA NA NA NA 14496 FUN_024588 1302 490 525 1110 694 NA NA NA NA NA NA NA 14497 FUN_008174 7 60 9 16 132 NA NA NA NA NA NA NA 14498 FUN_008176 6 0 0 0 0 NA NA NA NA NA NA NA 14499 FUN_008177 0 0 0 9 57 NA NA NA NA NA NA NA 14500 FUN_008170 69 0 0 0 0 NA NA NA NA NA NA NA 14501 FUN_008171 18 8 4 0 0 NA NA NA NA NA NA NA 14502 FUN_008172 168 2 2 3 0 NA NA NA NA NA NA NA 14503 FUN_029988 14 0 0 0 0 NA NA NA NA NA NA NA 14504 FUN_014268 1845 501 783 727 147 NA NA NA NA NA NA NA 14505 FUN_044105 102 229 275 237 648 NA NA NA NA NA NA NA 14506 FUN_014264 4251 4095 2457 554 196 NA NA NA NA NA NA NA 14507 FUN_044107 3 4 10 2 101 NA NA NA NA NA NA NA 14508 FUN_014261 43 43 15 32 23 NA NA NA NA NA NA NA 14509 FUN_014260 118 6 13 3 4 NA NA NA NA NA NA NA 14510 FUN_014263 9 61 9 48 87 NA NA NA NA NA NA NA 14511 FUN_044102 54 117 93 66 209 NA NA NA NA NA NA NA 14512 FUN_043159 1342 1946 710 1514 1374 NA NA NA NA NA NA NA 14513 FUN_011478 0 47 3 11 10 NA NA NA NA NA NA NA 14514 FUN_025183 0 0 0 0 30 NA NA NA NA NA NA NA 14515 FUN_025184 1 0 0 3 35 ptg000018l:15593837-15600047 Q9J569 1.75e-22 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 14516 FUN_025185 10 0 1 0 10 NA NA NA NA NA NA NA 14517 FUN_025187 5 0 1 0 33 NA NA NA NA NA NA NA 14518 FUN_044101 9 9 18 1 138 NA NA NA NA NA NA NA 14519 FUN_011475 4 21 7 20 53 NA NA NA NA NA NA NA 14520 FUN_015050 5513 11325 3261 12332 5876 NA NA NA NA NA NA NA 14521 FUN_043154 168 251 206 221 109 NA NA NA NA NA NA NA 14522 FUN_043152 107 32 21 42 81 NA NA NA NA NA NA NA 14523 FUN_008042 752 1335 1120 740 522 NA NA NA NA NA NA NA 14524 FUN_043042 0 3 9 0 2 NA NA NA NA NA NA NA 14525 FUN_011470 8 0 26 0 124 NA NA NA NA NA NA NA 14526 FUN_026350 97 189 105 441 623 NA NA NA NA NA NA NA 14527 FUN_014889 261 207 96 156 188 NA NA NA NA NA NA NA 14528 FUN_014881 482 1512 718 870 722 ptg000009l:3878591-3888027 Q08DY9 7.27e-29 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 14529 FUN_014881 482 1512 718 870 722 ptg000009l:3878591-3888027 Q08DY9 5.04e-28 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Bos taurus (Bovine) positive regulation of amyloid-beta formation [GO:1902004]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647] GO:0004175; GO:0005737; GO:0006508; GO:0031647; GO:0097153; GO:0097199; GO:0097200; GO:1902004 14530 FUN_014880 15674 14470 14052 23263 12861 ptg000009l:3870949-3877585 Q8WPW2 1.63e-21 Pyridoxal 5'-phosphate synthase subunit SNZERR (PLP synthase subunit SNZERR) (EC 4.3.3.6) (Ethylene response protein) (PDX1) Suberites domuncula (Sponge) pyridoxal phosphate biosynthetic process [GO:0042823] GO:0036381; GO:0042823 14531 FUN_014883 5033 6642 1555 3001 3058 NA NA NA NA NA NA NA 14532 FUN_014882 933 441 672 976 516 ptg000009l:3890673-3900519 P11862 5.19e-34 Growth arrest-specific protein 2 (GAS-2) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; antral ovarian follicle growth [GO:0001547]; apoptotic process [GO:0006915]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; initiation of primordial ovarian follicle growth [GO:0001544]; ovulation [GO:0030728]; regulation of cell cycle [GO:0051726]; regulation of cell shape [GO:0008360]; regulation of Notch signaling pathway [GO:0008593] GO:0001544; GO:0001547; GO:0005737; GO:0005884; GO:0006915; GO:0007049; GO:0008017; GO:0008093; GO:0008360; GO:0008593; GO:0016020; GO:0030728; GO:0051015; GO:0051726; GO:0051764; GO:0071711 14533 FUN_014885 683 899 659 620 429 NA NA NA NA NA NA NA 14534 FUN_014884 2672 6370 157 3766 3174 NA NA NA NA NA NA NA 14535 FUN_014887 349 184 111 232 92 NA NA NA NA NA NA NA 14536 FUN_014886 2487 850 999 1223 951 NA NA NA NA NA NA NA 14537 FUN_015132 0 0 0 32 14 NA NA NA NA NA NA NA 14538 FUN_029896 24 3 10 5 46 NA NA NA NA NA NA NA 14539 FUN_015130 0 0 0 0 7 NA NA NA NA NA NA NA 14540 FUN_015131 0 43 0 0 0 NA NA NA NA NA NA NA 14541 FUN_015136 1172 502 785 1402 916 NA NA NA NA NA NA NA 14542 FUN_015137 430 168 72 139 99 NA NA NA NA NA NA NA 14543 FUN_015134 10 9 29 5 60 NA NA NA NA NA NA NA 14544 FUN_015135 30 0 41 76 185 NA NA NA NA NA NA NA 14545 FUN_015138 412 401 357 436 488 ptg000009l:6672532-6675092 Q8BIY1 1.03e-27 G patch domain-containing protein 3 Mus musculus (Mouse) negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; positive regulation of DNA-templated transcription [GO:0045893] GO:0003676; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0032480; GO:0039536; GO:0045893 14546 FUN_015139 1382 581 856 1260 737 NA NA NA NA NA NA NA 14547 FUN_014114 1575 2221 1534 1020 1605 ptg000008l:31868992-31875839 P43004 1.25e-22 Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2) Homo sapiens (Human) adult behavior [GO:0030534]; cellular response to cocaine [GO:0071314]; cellular response to extracellular stimulus [GO:0031668]; chemical synaptic transmission [GO:0007268]; D-aspartate import across plasma membrane [GO:0070779]; glutathione biosynthetic process [GO:0006750]; ion transport [GO:0006811]; L-aspartate import across plasma membrane [GO:0140009]; L-aspartate transmembrane transport [GO:0070778]; L-glutamate import across plasma membrane [GO:0098712]; L-glutamate transmembrane transport [GO:0015813]; multicellular organism aging [GO:0010259]; multicellular organism growth [GO:0035264]; neurotransmitter reuptake [GO:0098810]; neurotransmitter transport [GO:0006836]; positive regulation of glucose import [GO:0046326]; protein homotrimerization [GO:0070207]; response to amino acid [GO:0043200]; response to wounding [GO:0009611]; response to xenobiotic stimulus [GO:0009410]; telencephalon development [GO:0021537]; transepithelial transport [GO:0070633]; transport across blood-brain barrier [GO:0150104]; visual behavior [GO:0007632] GO:0005313; GO:0005314; GO:0005886; GO:0006750; GO:0006811; GO:0006836; GO:0007268; GO:0007632; GO:0009410; GO:0009611; GO:0009986; GO:0010259; GO:0015175; GO:0015501; GO:0015813; GO:0016020; GO:0021537; GO:0030534; GO:0030673; GO:0031668; GO:0031982; GO:0033229; GO:0035264; GO:0042734; GO:0043200; GO:0044297; GO:0044306; GO:0045121; GO:0046326; GO:0046872; GO:0070207; GO:0070633; GO:0070778; GO:0070779; GO:0071314; GO:0097449; GO:0098712; GO:0098796; GO:0098810; GO:0098978; GO:0140009; GO:0150104 14548 FUN_014112 3039 2187 1358 2084 1524 ptg000008l:31847994-31859126 O57321 6.74e-22 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 14549 FUN_029890 1529 1121 765 1254 1451 NA NA NA NA NA NA NA 14550 FUN_014110 3037 1281 1414 2607 2285 ptg000008l:31828129-31839621 O57321 8.75e-23 Excitatory amino acid transporter 1 (SEAAT1) (Sodium-dependent glutamate/aspartate transporter) (GLAST) Ambystoma tigrinum (Eastern tiger salamander) chloride transmembrane transport [GO:1902476]; D-aspartate import across plasma membrane [GO:0070779]; L-aspartate import across plasma membrane [GO:0140009]; L-glutamate import across plasma membrane [GO:0098712]; potassium ion transmembrane transport [GO:0071805] GO:0005314; GO:0005886; GO:0015501; GO:0046872; GO:0070779; GO:0071805; GO:0098712; GO:0140009; GO:1902476 14551 FUN_038511 3885 2887 2354 3008 3706 NA NA NA NA NA NA NA 14552 FUN_038510 911 585 345 378 472 ptg000027l:8174807-8177438 Q4UMH6 4.8e-47 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 14553 FUN_038510 911 585 345 378 472 ptg000027l:8174807-8177438 Q4UMH6 1.96e-44 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 14554 FUN_038510 911 585 345 378 472 ptg000027l:8174807-8177438 Q4UMH6 1.75e-42 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 14555 FUN_038510 911 585 345 378 472 ptg000027l:8174807-8177438 Q4UMH6 2.44e-41 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 14556 FUN_038510 911 585 345 378 472 ptg000027l:8174807-8177438 Q4UMH6 2.06e-36 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 14557 FUN_038510 911 585 345 378 472 ptg000027l:8174807-8177438 Q4UMH6 5.61e-28 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 14558 FUN_038513 2327 2552 1193 2264 1347 NA NA NA NA NA NA NA 14559 FUN_038512 29409 19647 12075 21658 18706 ptg000027l:8180010-8197620 Q8K4K5 2.42e-27 Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; maintenance of apical/basal cell polarity [GO:0035090]; protein-containing complex assembly [GO:0065003]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] GO:0000137; GO:0000139; GO:0005096; GO:0005737; GO:0005856; GO:0005886; GO:0006887; GO:0006893; GO:0007409; GO:0008593; GO:0016323; GO:0019901; GO:0030424; GO:0030864; GO:0030866; GO:0031267; GO:0031901; GO:0032588; GO:0032878; GO:0035090; GO:0035748; GO:0045159; GO:0050708; GO:0051294; GO:0065003 14560 FUN_038512 29409 19647 12075 21658 18706 ptg000027l:8180010-8197620 Q8K4K5 2.07e-24 Lethal(2) giant larvae protein homolog 1 (LLGL) (Rgl-1) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cortical actin cytoskeleton organization [GO:0030866]; establishment of spindle orientation [GO:0051294]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; maintenance of apical/basal cell polarity [GO:0035090]; protein-containing complex assembly [GO:0065003]; regulation of establishment or maintenance of cell polarity [GO:0032878]; regulation of Notch signaling pathway [GO:0008593]; regulation of protein secretion [GO:0050708] GO:0000137; GO:0000139; GO:0005096; GO:0005737; GO:0005856; GO:0005886; GO:0006887; GO:0006893; GO:0007409; GO:0008593; GO:0016323; GO:0019901; GO:0030424; GO:0030864; GO:0030866; GO:0031267; GO:0031901; GO:0032588; GO:0032878; GO:0035090; GO:0035748; GO:0045159; GO:0050708; GO:0051294; GO:0065003 14561 FUN_038515 57 24 37 39 0 NA NA NA NA NA NA NA 14562 FUN_038514 2154 1387 227 1885 1411 NA NA NA NA NA NA NA 14563 FUN_038516 114 647 0 0 0 NA NA NA NA NA NA NA 14564 FUN_038519 0 0 0 26 0 NA NA NA NA NA NA NA 14565 FUN_038518 781 1147 108 412 280 NA NA NA NA NA NA NA 14566 FUN_031637 1432 1317 1022 785 495 ptg000023l:23710436-23714478 Q08DK7 7.11e-69 Mitochondrial basic amino acids transporter (Carnitine/acylcarnitine translocase-like) (CACT-like) (Mitochondrial carnitine/acylcarnitine carrier protein CACL) (Mitochondrial ornithine transporter 3) (Solute carrier family 25 member 29) Bos taurus (Bovine) acyl carnitine transport [GO:0006844]; L-arginine transmembrane transport [GO:1903826]; L-histidine transmembrane transport [GO:0089709]; L-lysine transmembrane transport [GO:1903401]; mitochondrial L-ornithine transmembrane transport [GO:1990575]; ornithine transport [GO:0015822] GO:0005289; GO:0005292; GO:0005739; GO:0005743; GO:0006844; GO:0015174; GO:0015822; GO:0022857; GO:0089709; GO:1903401; GO:1903826; GO:1990575 14567 FUN_031636 93 87 98 120 258 NA NA NA NA NA NA NA 14568 FUN_023910 11 1 9 0 0 NA NA NA NA NA NA NA 14569 FUN_023913 9 7 8 12 5 NA NA NA NA NA NA NA 14570 FUN_031630 1105 876 425 838 356 NA NA NA NA NA NA NA 14571 FUN_023919 0 0 0 0 6 NA NA NA NA NA NA NA 14572 FUN_023918 38 0 18 22 44 NA NA NA NA NA NA NA 14573 FUN_031639 509 358 184 350 517 NA NA NA NA NA NA NA 14574 FUN_031638 6442 4699 2719 3666 2715 ptg000023l:23717978-23722458 P25490 4.81e-28 Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; B cell differentiation [GO:0030183]; camera-type eye morphogenesis [GO:0048593]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to interleukin-1 [GO:0071347]; cellular response to UV [GO:0034644]; chromatin remodeling [GO:0006338]; double-strand break repair via homologous recombination [GO:0000724]; immunoglobulin heavy chain V-D-J recombination [GO:0071707]; negative regulation of cell growth involved in cardiac muscle cell development [GO:0061052]; negative regulation of gene expression [GO:0010629]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; regulation of transcription by RNA polymerase II [GO:0006357]; response to prostaglandin F [GO:0034696]; response to UV-C [GO:0010225]; RNA localization [GO:0006403]; spermatogenesis [GO:0007283]; telomere maintenance [GO:0000723] GO:0000122; GO:0000400; GO:0000723; GO:0000724; GO:0000976; GO:0000978; GO:0000981; GO:0000987; GO:0001217; GO:0001227; GO:0001228; GO:0003677; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005667; GO:0005677; GO:0005737; GO:0006275; GO:0006282; GO:0006338; GO:0006357; GO:0006403; GO:0006974; GO:0007283; GO:0009952; GO:0010225; GO:0010628; GO:0010629; GO:0016363; GO:0030183; GO:0031011; GO:0031519; GO:0032688; GO:0033044; GO:0034644; GO:0034696; GO:0045739; GO:0045893; GO:0045944; GO:0045995; GO:0046332; GO:0046872; GO:0048593; GO:0051726; GO:0060382; GO:0061052; GO:0071347; GO:0071707; GO:0140297; GO:1902894; GO:1904507; GO:1990837 14575 FUN_031211 4 14 19 0 0 NA NA NA NA NA NA NA 14576 FUN_014119 45 147 46 77 38 NA NA NA NA NA NA NA 14577 FUN_031210 1205 525 892 1737 1312 NA NA NA NA NA NA NA 14578 FUN_014118 667 76 209 359 190 NA NA NA NA NA NA NA 14579 FUN_036245 0 0 0 9 0 NA NA NA NA NA NA NA 14580 FUN_031212 1279 1366 804 918 798 NA NA NA NA NA NA NA 14581 FUN_031214 27 16 29 7 45 ptg000023l:18087025-18088153 Q9GZX3 2.5e-26 Carbohydrate sulfotransferase 6 (Corneal N-acetylglucosamine-6-O-sulfotransferase) (C-GlcNAc6ST) (hCGn6ST) (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta) (GST4-beta) (N-acetylglucosamine 6-O-sulfotransferase 5) (GlcNAc6ST-5) (Gn6st-5) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005794; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0018146; GO:0045130 14582 FUN_031217 97 35 69 72 17 ptg000023l:18104786-18106061 Q9GZX3 2.46e-26 Carbohydrate sulfotransferase 6 (Corneal N-acetylglucosamine-6-O-sulfotransferase) (C-GlcNAc6ST) (hCGn6ST) (EC 2.8.2.21) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta) (GST4-beta) (N-acetylglucosamine 6-O-sulfotransferase 5) (GlcNAc6ST-5) (Gn6st-5) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; keratan sulfate biosynthetic process [GO:0018146]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005794; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0018146; GO:0045130 14583 FUN_036240 724 411 330 1269 917 ptg000025l:16980698-16984023 P97846 2.4e-34 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 14584 FUN_003423 0 0 0 0 7 NA NA NA NA NA NA NA 14585 FUN_012589 1368 1360 492 1221 850 NA NA NA NA NA NA NA 14586 FUN_022312 1276 1110 905 801 1415 NA NA NA NA NA NA NA 14587 FUN_027111 0 0 0 0 22 NA NA NA NA NA NA NA 14588 FUN_027110 0 0 0 0 21 NA NA NA NA NA NA NA 14589 FUN_027113 0 0 0 0 25 NA NA NA NA NA NA NA 14590 FUN_027112 0 0 0 0 21 NA NA NA NA NA NA NA 14591 FUN_027115 0 0 0 0 26 NA NA NA NA NA NA NA 14592 FUN_027114 0 0 0 0 24 NA NA NA NA NA NA NA 14593 FUN_027117 0 0 0 0 18 NA NA NA NA NA NA NA 14594 FUN_027116 0 0 3 0 18 NA NA NA NA NA NA NA 14595 FUN_027119 0 2 2 0 73 NA NA NA NA NA NA NA 14596 FUN_027118 0 0 1 0 7 NA NA NA NA NA NA NA 14597 FUN_043127 3396 3062 1974 3528 2534 NA NA NA NA NA NA NA 14598 FUN_029667 1219 371 1134 25 895 NA NA NA NA NA NA NA 14599 FUN_029666 817 296 161 231 360 ptg000023l:4251503-4253499 F7H9X2 4.61e-41 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Callithrix jacchus (White-tufted-ear marmoset) regulation of neuron apoptotic process [GO:0043523] GO:0004842; GO:0005737; GO:0008270; GO:0043523 14600 FUN_027420 0 0 32 0 0 NA NA NA NA NA NA NA 14601 FUN_041246 13 40 1 37 8 NA NA NA NA NA NA NA 14602 FUN_016296 10766 8628 7022 14050 14532 ptg000011l:1239280-1272054 P41233 3.48e-31 Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; cholesterol transport [GO:0030301]; endosomal transport [GO:0016197]; establishment of localization in cell [GO:0051649]; export across plasma membrane [GO:0140115]; G protein-coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; intracellular cholesterol transport [GO:0032367]; lipid transport [GO:0006869]; lipoprotein biosynthetic process [GO:0042158]; lipoprotein metabolic process [GO:0042157]; lysosome organization [GO:0007040]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; phospholipid transport [GO:0015914]; platelet dense granule organization [GO:0060155]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of high-density lipoprotein particle assembly [GO:0090108]; protein lipidation [GO:0006497]; protein secretion [GO:0009306]; protein transmembrane transport [GO:0071806]; regulation of Cdc42 protein signal transduction [GO:0032489]; response to laminar fluid shear stress [GO:0034616]; reverse cholesterol transport [GO:0043691]; signal release [GO:0023061] GO:0002790; GO:0005102; GO:0005319; GO:0005524; GO:0005548; GO:0005768; GO:0005794; GO:0005886; GO:0006497; GO:0006869; GO:0006911; GO:0007040; GO:0007186; GO:0007189; GO:0008035; GO:0008203; GO:0008320; GO:0009306; GO:0009897; GO:0009986; GO:0010875; GO:0015914; GO:0016020; GO:0016197; GO:0016323; GO:0016887; GO:0019905; GO:0023061; GO:0030139; GO:0030301; GO:0031210; GO:0031267; GO:0032367; GO:0032489; GO:0033344; GO:0033700; GO:0034185; GO:0034186; GO:0034188; GO:0034380; GO:0034616; GO:0042157; GO:0042158; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0045121; GO:0045332; GO:0045335; GO:0046623; GO:0048471; GO:0051117; GO:0051649; GO:0055091; GO:0060155; GO:0071222; GO:0071300; GO:0071806; GO:0090108; GO:0090554; GO:0090556; GO:0097708; GO:0120020; GO:0140115; GO:0140328; GO:0140359 14603 FUN_029668 45 0 47 1 35 NA NA NA NA NA NA NA 14604 FUN_033960 47 34 23 39 32 NA NA NA NA NA NA NA 14605 FUN_033963 81 38 36 61 31 NA NA NA NA NA NA NA 14606 FUN_033962 157 84 122 217 440 NA NA NA NA NA NA NA 14607 FUN_033965 46 82 73 79 90 NA NA NA NA NA NA NA 14608 FUN_004258 1527 688 284 594 450 NA NA NA NA NA NA NA 14609 FUN_033967 168 65 152 159 484 NA NA NA NA NA NA NA 14610 FUN_033966 710 496 547 786 749 ptg000024l:3211951-3219616 Q9I830 2.81e-60 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 14611 FUN_041248 78 74 154 40 70 NA NA NA NA NA NA NA 14612 FUN_004254 847 513 630 680 648 ntLink_8:21303075-21311088 Q4V890 6.34e-37 Protein fem-1 homolog A (FEM1a) (FEM1-alpha) Rattus norvegicus (Rat) negative regulation of inflammatory response [GO:0050728]; negative regulation of MAP kinase activity [GO:0043407]; positive regulation of inflammatory response [GO:0050729]; protein ubiquitination [GO:0016567]; regulation of ubiquitin-protein transferase activity [GO:0051438]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0000151; GO:0005739; GO:0006511; GO:0016567; GO:0031462; GO:0031867; GO:0043407; GO:0050728; GO:0050729; GO:0051438; GO:0140627; GO:1990756 14613 FUN_004254 847 513 630 680 648 ntLink_8:21303075-21311088 Q4V890 4.29e-22 Protein fem-1 homolog A (FEM1a) (FEM1-alpha) Rattus norvegicus (Rat) negative regulation of inflammatory response [GO:0050728]; negative regulation of MAP kinase activity [GO:0043407]; positive regulation of inflammatory response [GO:0050729]; protein ubiquitination [GO:0016567]; regulation of ubiquitin-protein transferase activity [GO:0051438]; ubiquitin-dependent protein catabolic process [GO:0006511]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0000151; GO:0005739; GO:0006511; GO:0016567; GO:0031462; GO:0031867; GO:0043407; GO:0050728; GO:0050729; GO:0051438; GO:0140627; GO:1990756 14614 FUN_004257 38 0 12 10 155 NA NA NA NA NA NA NA 14615 FUN_004256 376 318 176 343 115 NA NA NA NA NA NA NA 14616 FUN_004251 1928 1114 721 1446 1135 ntLink_8:21262209-21271605 P34385 6.04e-38 Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) Caenorhabditis elegans leucine catabolic process [GO:0006552] GO:0004485; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0006552; GO:1905202 14617 FUN_004250 192 52 85 27 255 NA NA NA NA NA NA NA 14618 FUN_004253 767 616 259 435 546 NA NA NA NA NA NA NA 14619 FUN_004252 1446 1392 618 1254 1277 NA NA NA NA NA NA NA 14620 FUN_024887 0 24 47 69 137 ptg000018l:12193361-12198133 Q9U6Y5 7.43e-37 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 14621 FUN_024887 0 24 47 69 137 ptg000018l:12193361-12198133 Q9U6Y5 2.24e-34 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 14622 FUN_015756 12 119 2 262 76 NA NA NA NA NA NA NA 14623 FUN_015757 12 0 8 11 22 NA NA NA NA NA NA NA 14624 FUN_040106 1331 591 802 882 842 NA NA NA NA NA NA NA 14625 FUN_010986 638 469 296 614 540 NA NA NA NA NA NA NA 14626 FUN_019118 0 0 0 217 10 NA NA NA NA NA NA NA 14627 FUN_019119 0 11 0 2 0 NA NA NA NA NA NA NA 14628 FUN_019110 11 4 0 7 20 NA NA NA NA NA NA NA 14629 FUN_019112 0 0 1 0 72 NA NA NA NA NA NA NA 14630 FUN_019116 0 0 0 84 42 NA NA NA NA NA NA NA 14631 FUN_019117 0 0 0 0 93 NA NA NA NA NA NA NA 14632 FUN_025733 865 1167 1031 1795 2415 NA NA NA NA NA NA NA 14633 FUN_030229 2 0 2 0 16 ptg000023l:10413954-10414717 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14634 FUN_030227 1 0 2 1 10 ptg000023l:10409902-10410665 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14635 FUN_030225 3 0 2 0 15 ptg000023l:10405850-10406613 P84239 1.5e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14636 FUN_030223 2 0 3 0 8 ptg000023l:10401798-10402561 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14637 FUN_012391 561 656 325 249 282 NA NA NA NA NA NA NA 14638 FUN_030221 3 0 2 0 8 ptg000023l:10397750-10398513 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14639 FUN_012397 279 49 98 84 204 NA NA NA NA NA NA NA 14640 FUN_021478 255 566 59 196 173 ptg000016l:2406597-2409395 P48039 1.52e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; mating behavior [GO:0007617] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007193; GO:0007617; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0097159 14641 FUN_021479 1626 1332 621 1462 1286 NA NA NA NA NA NA NA 14642 FUN_021470 913 243 391 694 526 NA NA NA NA NA NA NA 14643 FUN_021473 2208 1029 1296 1857 1586 NA NA NA NA NA NA NA 14644 FUN_021474 45 20 23 78 3 NA NA NA NA NA NA NA 14645 FUN_021475 0 0 0 0 7 NA NA NA NA NA NA NA 14646 FUN_021477 0 36 0 13 0 NA NA NA NA NA NA NA 14647 FUN_042208 33 19 14 239 0 NA NA NA NA NA NA NA 14648 FUN_016129 3186 2128 1830 2988 2424 NA NA NA NA NA NA NA 14649 FUN_006304 0 0 11 0 0 NA NA NA NA NA NA NA 14650 FUN_042105 331 358 260 143 281 NA NA NA NA NA NA NA 14651 FUN_035479 1443 1194 678 1447 1384 NA NA NA NA NA NA NA 14652 FUN_016124 97 121 114 64 81 ptg000010l:1863284-1864175 Q5XGD7 4.66e-31 Transmembrane protein 45B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 14653 FUN_016125 6743 4363 4565 10057 5846 ptg000010l:1870272-1878232 Q8VI36 1.8e-38 Paxillin Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endothelial cell migration [GO:0043542]; focal adhesion assembly [GO:0048041]; growth hormone receptor signaling pathway [GO:0060396]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell shape [GO:0008360]; response to peptide [GO:1901652]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001725; GO:0003712; GO:0005078; GO:0005178; GO:0005829; GO:0005886; GO:0005911; GO:0005925; GO:0005938; GO:0007010; GO:0007179; GO:0007229; GO:0008013; GO:0008360; GO:0016477; GO:0017166; GO:0018108; GO:0019901; GO:0019903; GO:0030027; GO:0030032; GO:0030159; GO:0031252; GO:0034446; GO:0038191; GO:0043542; GO:0044877; GO:0045766; GO:0045860; GO:0046872; GO:0048041; GO:0048754; GO:0051435; GO:0051496; GO:0060396; GO:1901652 14654 FUN_016125 6743 4363 4565 10057 5846 ptg000010l:1870272-1878232 Q8VI36 1.34e-35 Paxillin Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endothelial cell migration [GO:0043542]; focal adhesion assembly [GO:0048041]; growth hormone receptor signaling pathway [GO:0060396]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell shape [GO:0008360]; response to peptide [GO:1901652]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001725; GO:0003712; GO:0005078; GO:0005178; GO:0005829; GO:0005886; GO:0005911; GO:0005925; GO:0005938; GO:0007010; GO:0007179; GO:0007229; GO:0008013; GO:0008360; GO:0016477; GO:0017166; GO:0018108; GO:0019901; GO:0019903; GO:0030027; GO:0030032; GO:0030159; GO:0031252; GO:0034446; GO:0038191; GO:0043542; GO:0044877; GO:0045766; GO:0045860; GO:0046872; GO:0048041; GO:0048754; GO:0051435; GO:0051496; GO:0060396; GO:1901652 14655 FUN_016125 6743 4363 4565 10057 5846 ptg000010l:1870272-1878232 Q8VI36 1.8e-26 Paxillin Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cell migration [GO:0016477]; cytoskeleton organization [GO:0007010]; endothelial cell migration [GO:0043542]; focal adhesion assembly [GO:0048041]; growth hormone receptor signaling pathway [GO:0060396]; integrin-mediated signaling pathway [GO:0007229]; lamellipodium assembly [GO:0030032]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of angiogenesis [GO:0045766]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of stress fiber assembly [GO:0051496]; regulation of cell shape [GO:0008360]; response to peptide [GO:1901652]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001725; GO:0003712; GO:0005078; GO:0005178; GO:0005829; GO:0005886; GO:0005911; GO:0005925; GO:0005938; GO:0007010; GO:0007179; GO:0007229; GO:0008013; GO:0008360; GO:0016477; GO:0017166; GO:0018108; GO:0019901; GO:0019903; GO:0030027; GO:0030032; GO:0030159; GO:0031252; GO:0034446; GO:0038191; GO:0043542; GO:0044877; GO:0045766; GO:0045860; GO:0046872; GO:0048041; GO:0048754; GO:0051435; GO:0051496; GO:0060396; GO:1901652 14656 FUN_006301 0 0 0 20 34 NA NA NA NA NA NA NA 14657 FUN_035473 1822 845 630 818 596 NA NA NA NA NA NA NA 14658 FUN_035472 0 0 0 41 66 NA NA NA NA NA NA NA 14659 FUN_042206 0 0 3 46 2 NA NA NA NA NA NA NA 14660 FUN_035477 1480 949 715 802 801 NA NA NA NA NA NA NA 14661 FUN_035476 4010 2018 1877 3834 2907 NA NA NA NA NA NA NA 14662 FUN_042207 0 0 0 13 0 NA NA NA NA NA NA NA 14663 FUN_026519 62 0 0 116 88 NA NA NA NA NA NA NA 14664 FUN_016120 0 89 31 0 42 NA NA NA NA NA NA NA 14665 FUN_042100 276 492 193 238 412 NA NA NA NA NA NA NA 14666 FUN_031575 0 0 28 54 0 NA NA NA NA NA NA NA 14667 FUN_031576 25 27 34 484 68 NA NA NA NA NA NA NA 14668 FUN_031577 18 65 49 105 22 NA NA NA NA NA NA NA 14669 FUN_031570 0 28 122 67 119 ptg000023l:23002669-23005059 Q5UU75 9.28e-22 Doublesex- and mab-3-related transcription factor A2 (Doublesex- and mab-3-related transcription factor 5) Danio rerio (Zebrafish) (Brachydanio rerio) corticotropin hormone secreting cell differentiation [GO:0060128]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548]; telencephalon development [GO:0021537] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007548; GO:0021537; GO:0046872; GO:0060128 14670 FUN_031571 1208 149 284 129 108 NA NA NA NA NA NA NA 14671 FUN_031573 206 161 92 228 0 NA NA NA NA NA NA NA 14672 FUN_035234 84 39 75 23 135 ptg000025l:5431834-5432902 O35214 1.23e-28 Visual pigment-like receptor peropsin Mus musculus (Mouse) cellular response to light stimulus [GO:0071482]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0001750; GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0071482 14673 FUN_032179 1082 648 636 649 487 NA NA NA NA NA NA NA 14674 FUN_032178 0 2 8 8 11 NA NA NA NA NA NA NA 14675 FUN_032175 2 0 6 14 11 NA NA NA NA NA NA NA 14676 FUN_032174 12 11 90 52 454 NA NA NA NA NA NA NA 14677 FUN_032177 12 9 126 84 614 NA NA NA NA NA NA NA 14678 FUN_032176 1 1 3 1 9 NA NA NA NA NA NA NA 14679 FUN_032171 6 4 34 14 143 NA NA NA NA NA NA NA 14680 FUN_032170 2 2 2 7 13 NA NA NA NA NA NA NA 14681 FUN_032173 2 2 4 15 12 NA NA NA NA NA NA NA 14682 FUN_032172 4 2 18 26 63 NA NA NA NA NA NA NA 14683 FUN_015243 3718 3617 2034 12742 8154 ptg000009l:7859596-7865915 B3EX00 4.92e-122 Uncharacterized skeletal organic matrix protein 1 (Uncharacterized SOMP-1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 14684 FUN_015243 3718 3617 2034 12742 8154 ptg000009l:7859596-7865915 B3EX00 3.41e-52 Uncharacterized skeletal organic matrix protein 1 (Uncharacterized SOMP-1) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 14685 FUN_008372 5437 5622 1802 3826 1612 NA NA NA NA NA NA NA 14686 FUN_008373 890 307 261 832 1436 NA NA NA NA NA NA NA 14687 FUN_008370 3535 3489 2363 3191 2632 NA NA NA NA NA NA NA 14688 FUN_008371 1447 921 703 1614 1832 NA NA NA NA NA NA NA 14689 FUN_008376 378 220 749 1015 226 ptg000002l:10896257-10900432 Q8N0P0 5.19e-26 Octopine dehydrogenase (OcDH) (EC 1.5.1.11) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) NA GO:0047830 14690 FUN_008377 2849 63 13356 7351 399 NA NA NA NA NA NA NA 14691 FUN_005393 3 159 26 112 0 NA NA NA NA NA NA NA 14692 FUN_005392 4 59 39 61 0 NA NA NA NA NA NA NA 14693 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.37e-63 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14694 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.37e-63 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14695 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.37e-63 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14696 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.05e-47 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14697 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.05e-47 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14698 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.05e-47 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14699 FUN_005390 445 295 331 297 237 ntLink_8:34818085-34896627 P20825 1.05e-47 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 14700 FUN_000145 2 0 3 0 19 ntLink_4:224073-224854 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14701 FUN_005395 1 88 0 234 94 NA NA NA NA NA NA NA 14702 FUN_000146 2 0 3 0 24 ntLink_4:228139-228918 P84239 4.85e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14703 FUN_000149 18 2 34 6 190 ntLink_4:235183-237625 P35067 3.94e-76 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 14704 FUN_018306 805 41 491 121 53 ptg000012l:7410660-7414709 Q96AY4 1.02e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14705 FUN_018306 805 41 491 121 53 ptg000012l:7410660-7414709 Q96AY4 2.12e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14706 FUN_018306 805 41 491 121 53 ptg000012l:7410660-7414709 Q96AY4 1.09e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14707 FUN_018306 805 41 491 121 53 ptg000012l:7410660-7414709 Q96AY4 2.6e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14708 FUN_018306 805 41 491 121 53 ptg000012l:7410660-7414709 Q96AY4 6.86e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14709 FUN_018307 238 55 112 163 42 NA NA NA NA NA NA NA 14710 FUN_018304 542 230 372 287 0 NA NA NA NA NA NA NA 14711 FUN_007731 14 222 2 0 34 NA NA NA NA NA NA NA 14712 FUN_007730 0 292 0 0 0 NA NA NA NA NA NA NA 14713 FUN_007735 0 48 0 0 0 NA NA NA NA NA NA NA 14714 FUN_007734 4 71 0 25 8 NA NA NA NA NA NA NA 14715 FUN_007739 0 43 0 0 0 NA NA NA NA NA NA NA 14716 FUN_007738 0 0 7 7 10 NA NA NA NA NA NA NA 14717 FUN_034374 14 2 14 4 19 NA NA NA NA NA NA NA 14718 FUN_032799 0 0 5 12 41 ptg000023l:36050491-36052088 O42574 2.14e-30 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 14719 FUN_032791 5185 4243 2233 3420 2220 NA NA NA NA NA NA NA 14720 FUN_032790 1909 1319 1268 1568 1888 NA NA NA NA NA NA NA 14721 FUN_034376 3323 2435 1695 3317 2580 NA NA NA NA NA NA NA 14722 FUN_032795 0 6 28 2 68 ptg000023l:36041058-36042060 P53454 5.84e-26 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 14723 FUN_032794 66 60 40 61 17 NA NA NA NA NA NA NA 14724 FUN_032796 3907 1192 427 3745 762 NA NA NA NA NA NA NA 14725 FUN_041446 39 7 41 90 143 NA NA NA NA NA NA NA 14726 FUN_013965 0 0 0 0 12 NA NA NA NA NA NA NA 14727 FUN_013964 41 0 7 0 180 NA NA NA NA NA NA NA 14728 FUN_005641 0 0 3 0 10 NA NA NA NA NA NA NA 14729 FUN_005640 0 0 9 0 4 NA NA NA NA NA NA NA 14730 FUN_013960 326 0 130 7 49 NA NA NA NA NA NA NA 14731 FUN_005648 0 0 4 0 19 NA NA NA NA NA NA NA 14732 FUN_033222 1919 1470 1045 1440 1950 NA NA NA NA NA NA NA 14733 FUN_033223 1276 1403 759 1175 1253 NA NA NA NA NA NA NA 14734 FUN_033220 15 0 0 0 8 NA NA NA NA NA NA NA 14735 FUN_033221 802 622 388 821 648 NA NA NA NA NA NA NA 14736 FUN_033224 154 148 3 580 158 NA NA NA NA NA NA NA 14737 FUN_033225 0 6 6 0 64 NA NA NA NA NA NA NA 14738 FUN_006614 467 617 185 574 702 NA NA NA NA NA NA NA 14739 FUN_035704 263 213 206 6 264 NA NA NA NA NA NA NA 14740 FUN_003494 0 0 32 91 156 NA NA NA NA NA NA NA 14741 FUN_005092 409 130 154 262 176 NA NA NA NA NA NA NA 14742 FUN_003498 0 0 33 14 49 NA NA NA NA NA NA NA 14743 FUN_005093 729 258 183 477 216 NA NA NA NA NA NA NA 14744 FUN_005094 225 105 53 71 75 NA NA NA NA NA NA NA 14745 FUN_032541 0 704 7 6 187 NA NA NA NA NA NA NA 14746 FUN_005096 32 0 1 16 0 NA NA NA NA NA NA NA 14747 FUN_005097 128 77 27 647 43 NA NA NA NA NA NA NA 14748 FUN_003728 9 0 35 0 32 NA NA NA NA NA NA NA 14749 FUN_004118 647 491 399 398 452 NA NA NA NA NA NA NA 14750 FUN_004119 448 282 159 106 354 NA NA NA NA NA NA NA 14751 FUN_026557 15 11 4 14 1 NA NA NA NA NA NA NA 14752 FUN_004112 515 976 1121 390 251 NA NA NA NA NA NA NA 14753 FUN_003721 119 36 13 39 9 ntLink_8:14744466-14761734 Q5I2E5 6.38e-42 Ficolin-2 (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin-beta) (L-ficolin) Bos taurus (Bovine) complement activation, lectin pathway [GO:0001867] GO:0001867; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0030246; GO:0046872; GO:0062023; GO:0097367 14754 FUN_003721 119 36 13 39 9 ntLink_8:14744466-14761734 Q5I2E5 1.1e-37 Ficolin-2 (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin-beta) (L-ficolin) Bos taurus (Bovine) complement activation, lectin pathway [GO:0001867] GO:0001867; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0030246; GO:0046872; GO:0062023; GO:0097367 14755 FUN_003722 19 0 0 40 7 NA NA NA NA NA NA NA 14756 FUN_003723 0 0 4 9 1 NA NA NA NA NA NA NA 14757 FUN_004116 1072 368 296 359 382 NA NA NA NA NA NA NA 14758 FUN_004117 698 836 1149 957 687 ntLink_8:19494670-19508677 P70270 2.67e-22 DNA repair and recombination protein RAD54-like (EC 3.6.4.12) (RAD54 homolog) (mHR54) (mRAD54) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212]; response to xenobiotic stimulus [GO:0009410] GO:0000724; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0006302; GO:0006974; GO:0007131; GO:0008340; GO:0009410; GO:0010212; GO:0015616; GO:0016887; GO:0032991; GO:0036310; GO:0045003; GO:0046872; GO:0051276; GO:0140658 14759 FUN_004114 1196 656 187 628 412 ntLink_8:19388816-19423938 P93804 3.45e-22 Phosphoglucomutase, cytoplasmic 1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) Zea mays (Maize) carbohydrate metabolic process [GO:0005975]; glucose metabolic process [GO:0006006] GO:0000287; GO:0004614; GO:0005829; GO:0005975; GO:0006006 14760 FUN_003727 126 0 87 61 0 NA NA NA NA NA NA NA 14761 FUN_040311 201 792 104 487 423 ptg000031l:6831713-6844128 Q7RTR2 2.8e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14762 FUN_040311 201 792 104 487 423 ptg000031l:6831713-6844128 Q7RTR2 4.49e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14763 FUN_040311 201 792 104 487 423 ptg000031l:6831713-6844128 Q7RTR2 9.79e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14764 FUN_040311 201 792 104 487 423 ptg000031l:6831713-6844128 Q7RTR2 6.69e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14765 FUN_040313 203 95 81 470 427 ptg000031l:6881944-6888434 Q7RTR2 6.17e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14766 FUN_040313 203 95 81 470 427 ptg000031l:6881944-6888434 Q7RTR2 2.13e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14767 FUN_040313 203 95 81 470 427 ptg000031l:6881944-6888434 Q7RTR2 6.84e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14768 FUN_040313 203 95 81 470 427 ptg000031l:6881944-6888434 Q7RTR2 1.29e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14769 FUN_040313 203 95 81 470 427 ptg000031l:6881944-6888434 Q7RTR2 9.62e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 14770 FUN_028536 0 0 0 0 19 NA NA NA NA NA NA NA 14771 FUN_040318 42 5 12 0 19 NA NA NA NA NA NA NA 14772 FUN_026553 8159 3535 2320 3390 1325 NA NA NA NA NA NA NA 14773 FUN_034793 36 34 15 6 0 NA NA NA NA NA NA NA 14774 FUN_034792 81 62 22 98 63 NA NA NA NA NA NA NA 14775 FUN_034791 6070 4079 2259 5205 3911 NA NA NA NA NA NA NA 14776 FUN_034790 364 192 115 796 304 NA NA NA NA NA NA NA 14777 FUN_034797 7081 5195 3778 6826 2928 ptg000025l:265148-268387 Q8BM54 1.09e-46 E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain-interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) Mus musculus (Mouse) cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630; GO:0071404 14778 FUN_034797 7081 5195 3778 6826 2928 ptg000025l:265148-268387 Q8BM54 1.56e-37 E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain-interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) Mus musculus (Mouse) cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630; GO:0071404 14779 FUN_034795 1513 668 454 698 677 NA NA NA NA NA NA NA 14780 FUN_034794 82 173 64 118 128 NA NA NA NA NA NA NA 14781 FUN_034799 2434 1598 1509 2404 2402 NA NA NA NA NA NA NA 14782 FUN_034798 184 100 26 72 122 ptg000025l:274012-275332 P16388 4.48e-87 Potassium voltage-gated channel subfamily A member 1 (MBK1) (MKI) (Voltage-gated potassium channel subunit Kv1.1) Mus musculus (Mouse) axon development [GO:0061564]; brain development [GO:0007420]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005783; GO:0005829; GO:0005886; GO:0006937; GO:0007405; GO:0007420; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030424; GO:0030425; GO:0031410; GO:0033270; GO:0034705; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 14783 FUN_022079 4703 2889 2371 3779 1597 NA NA NA NA NA NA NA 14784 FUN_028258 3 0 0 12 0 NA NA NA NA NA NA NA 14785 FUN_028256 0 0 0 13 0 NA NA NA NA NA NA NA 14786 FUN_028255 0 0 0 17 0 NA NA NA NA NA NA NA 14787 FUN_028254 0 0 0 8 0 NA NA NA NA NA NA NA 14788 FUN_028253 4 7 0 84 0 NA NA NA NA NA NA NA 14789 FUN_028252 11 4 37 67 36 NA NA NA NA NA NA NA 14790 FUN_028251 1359 1741 783 570 689 ptg000021l:17350812-17369810 Q9JHW2 3.75e-27 Omega-amidase NIT2 (EC 3.5.1.3) (Nitrilase homolog 2) Mus musculus (Mouse) asparagine metabolic process [GO:0006528]; glutamine metabolic process [GO:0006541]; oxaloacetate metabolic process [GO:0006107] GO:0005739; GO:0005813; GO:0005829; GO:0006107; GO:0006528; GO:0006541; GO:0050152; GO:0106008 14791 FUN_028250 772 488 197 628 279 ptg000021l:17342614-17346195 Q6ITT3 2.28e-39 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 14792 FUN_031466 2905 2948 1587 2319 1311 ptg000023l:21771791-21775855 Q5TYW6 3.93e-22 Radial spoke head protein 9 homolog Danio rerio (Zebrafish) (Brachydanio rerio) axonemal central apparatus assembly [GO:1904158]; axoneme assembly [GO:0035082]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; cilium movement involved in cell motility [GO:0060294]; motile cilium assembly [GO:0044458]; radial spoke assembly [GO:0062177] GO:0001534; GO:0003341; GO:0005929; GO:0005930; GO:0031514; GO:0035082; GO:0044458; GO:0060091; GO:0060271; GO:0060294; GO:0062177; GO:1904158 14793 FUN_023804 18 9 9 0 45 NA NA NA NA NA NA NA 14794 FUN_031467 4136 2229 2124 3744 2934 ptg000023l:21777295-21802126 Q5RDQ2 3.85e-32 Protein PALS1 (MAGUK p55 subfamily member 5) (Protein associated with Lin-7 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) central nervous system neuron development [GO:0021954]; cerebral cortex development [GO:0021987]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015] GO:0005524; GO:0005794; GO:0005912; GO:0005923; GO:0016324; GO:0017015; GO:0021954; GO:0021987; GO:0030424; GO:0043204 14795 FUN_028855 4 0 0 0 21 NA NA NA NA NA NA NA 14796 FUN_028854 0 25 35 0 196 NA NA NA NA NA NA NA 14797 FUN_034245 230 177 150 600 183 ptg000024l:6488096-6519163 Q9NBX4 7.55e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 14798 FUN_034245 230 177 150 600 183 ptg000024l:6488096-6519163 Q9NBX4 7.55e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 14799 FUN_034244 721 458 646 635 209 NA NA NA NA NA NA NA 14800 FUN_034246 1349 698 207 976 1141 NA NA NA NA NA NA NA 14801 FUN_034241 154 213 111 326 64 NA NA NA NA NA NA NA 14802 FUN_023801 1189 473 1274 1655 1741 ptg000017l:11486899-11668400 Q96DM1 6.61e-94 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 14803 FUN_034243 112 153 246 124 0 NA NA NA NA NA NA NA 14804 FUN_034242 1642 516 222 1280 1993 NA NA NA NA NA NA NA 14805 FUN_028856 15 9 11 1 150 NA NA NA NA NA NA NA 14806 FUN_034249 442 2564 182 266 557 NA NA NA NA NA NA NA 14807 FUN_034248 43 24 0 0 41 NA NA NA NA NA NA NA 14808 FUN_031463 232 261 120 203 315 ptg000023l:21754107-21756922 B9IUR6 9.75e-45 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain Q1) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 14809 FUN_002459 0 0 59 0 55 NA NA NA NA NA NA NA 14810 FUN_002458 19 0 12 0 27 NA NA NA NA NA NA NA 14811 FUN_002451 6544 4892 3351 4927 3972 NA NA NA NA NA NA NA 14812 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 7.49e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14813 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 7.43e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14814 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 3.86e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14815 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 4.68e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14816 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 6.65e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14817 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 7.61e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14818 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 8.46e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14819 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 7.01e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14820 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 1.95e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14821 FUN_002450 314 128 270 408 95 ntLink_8:1695469-1725412 Q96AY4 2.28e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14822 FUN_002453 3465 3036 2540 4692 3408 NA NA NA NA NA NA NA 14823 FUN_002452 6303 5508 2994 6072 2576 NA NA NA NA NA NA NA 14824 FUN_002455 172 92 78 232 83 NA NA NA NA NA NA NA 14825 FUN_002454 1113 742 608 838 832 ntLink_8:1786802-1795604 Q62070 6.61e-33 Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; G1/S transition of mitotic cell cycle [GO:0000082]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of mitotic cell cycle [GO:0007346] GO:0000082; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0006915; GO:0007346; GO:0008285; GO:0008637; GO:0010508; GO:0016236; GO:0016239; GO:0032091; GO:0043066; GO:0043123; GO:0045893; GO:0046777; GO:0050821; GO:0106310 14826 FUN_002457 355 87 124 221 85 ntLink_8:1803380-1819565 Q3UHK1 4.39e-69 Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) Mus musculus (Mouse) myo-inositol transport [GO:0015798]; positive regulation of amyloid-beta formation [GO:1902004]; transmembrane transport [GO:0055085] GO:0002020; GO:0005365; GO:0005366; GO:0005737; GO:0005886; GO:0015798; GO:0016020; GO:0016324; GO:0022857; GO:0030426; GO:0031090; GO:0042995; GO:0043231; GO:0044297; GO:0051117; GO:0055085; GO:0071944; GO:0097450; GO:1902004 14827 FUN_017962 0 0 0 0 92 ptg000012l:2431310-2437219 A0A0D3QS97 2.94e-28 Palmitoleoyl-protein carboxylesterase notum2 (EC 3.1.1.98) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0005576; GO:0016055; GO:0016787 14828 FUN_012366 1251 1341 819 1936 1910 ptg000008l:8284900-8324894 Q6TCH4 3.06e-32 Membrane progestin receptor delta (mPR delta) (Membrane progesterone P4 receptor delta) (Membrane progesterone receptor delta) (Progesterone and adipoQ receptor family member 6) (Progestin and adipoQ receptor family member 6) Homo sapiens (Human) NA GO:0005496; GO:0005886; GO:0038023 14829 FUN_012367 12 0 1 33 30 NA NA NA NA NA NA NA 14830 FUN_012364 82 91 17 76 19 NA NA NA NA NA NA NA 14831 FUN_012365 78 78 108 77 142 NA NA NA NA NA NA NA 14832 FUN_012362 31 88 10 106 122 ptg000008l:8268897-8269843 Q9YGL7 2.71e-68 Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1) Gallus gallus (Chicken) positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0045944 14833 FUN_012363 523 328 260 749 636 ptg000008l:8272182-8275723 Q5BK81 7.85e-27 Prostaglandin reductase 2 (PRG-2) (EC 1.3.1.48) (15-oxoprostaglandin 13-reductase) (Zinc-binding alcohol dehydrogenase domain-containing protein 1) Rattus norvegicus (Rat) prostaglandin metabolic process [GO:0006693] GO:0005737; GO:0006693; GO:0036132; GO:0047522 14834 FUN_012360 7050 5722 5295 6462 3962 NA NA NA NA NA NA NA 14835 FUN_012361 9098 12005 3918 11982 5068 NA NA NA NA NA NA NA 14836 FUN_014401 0 0 12 0 2 NA NA NA NA NA NA NA 14837 FUN_014403 13 0 12 0 5 NA NA NA NA NA NA NA 14838 FUN_043158 2483 1316 1186 2221 1559 NA NA NA NA NA NA NA 14839 FUN_043156 6139 4463 2546 5101 4875 ptg000047l:4711773-4737575 Q16513 1.19e-21 Serine/threonine-protein kinase N2 (EC 2.7.11.13) (PKN gamma) (Protein kinase C-like 2) (Protein-kinase C-related kinase 2) Homo sapiens (Human) apical junction assembly [GO:0043297]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell projection organization [GO:0030030]; epithelial cell migration [GO:0010631]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cytokinesis [GO:0032467]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of viral genome replication [GO:0045070]; protein phosphorylation [GO:0006468]; regulation of cell motility [GO:2000145]; signal transduction [GO:0007165] GO:0003723; GO:0004672; GO:0004674; GO:0004698; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0006468; GO:0006915; GO:0007049; GO:0007155; GO:0007165; GO:0010631; GO:0016301; GO:0016604; GO:0018105; GO:0030027; GO:0030030; GO:0030496; GO:0031267; GO:0032154; GO:0032467; GO:0032991; GO:0035556; GO:0042826; GO:0043296; GO:0043297; GO:0045070; GO:0045111; GO:0045296; GO:0045931; GO:0048471; GO:0051301; GO:0070063; GO:0106310; GO:2000145 14840 FUN_043155 73 41 22 0 57 NA NA NA NA NA NA NA 14841 FUN_011474 91 12 83 11 405 NA NA NA NA NA NA NA 14842 FUN_043153 152 62 110 120 71 ptg000047l:4700084-4701315 O88796 2.45e-52 Ribonuclease P protein subunit p30 (RNaseP protein p30) (RNase P subunit 2) Mus musculus (Mouse) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; rRNA processing [GO:0006364]; tRNA 5'-leader removal [GO:0001682]; tRNA processing [GO:0008033] GO:0000172; GO:0001682; GO:0003723; GO:0004526; GO:0005655; GO:0006364; GO:0008033; GO:0030681; GO:0033204; GO:0090502 14843 FUN_043151 3406 2657 1607 3045 2276 NA NA NA NA NA NA NA 14844 FUN_043150 20 8 0 14 20 NA NA NA NA NA NA NA 14845 FUN_000916 2003 1521 1124 2025 1587 ntLink_6:6017725-6025267 O43581 7.42e-48 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 14846 FUN_000916 2003 1521 1124 2025 1587 ntLink_6:6017725-6025267 O43581 1.45e-24 Synaptotagmin-7 (IPCA-7) (Prostate cancer-associated protein 7) (Synaptotagmin VII) (SytVII) Homo sapiens (Human) calcium ion regulated lysosome exocytosis [GO:1990927]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; phagocytosis [GO:0006909]; phagosome-lysosome fusion [GO:0090385]; plasma membrane repair [GO:0001778]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of bone remodeling [GO:0046850]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of glucagon secretion [GO:0070092]; regulation of insulin secretion [GO:0050796]; regulation of phagocytosis [GO:0050764]; regulation of synaptic vesicle endocytosis [GO:1900242]; short-term synaptic potentiation [GO:1990926]; synaptic vesicle recycling [GO:0036465]; vesicle-mediated cholesterol transport [GO:0090119]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001778; GO:0001786; GO:0005509; GO:0005516; GO:0005544; GO:0005546; GO:0005764; GO:0005765; GO:0005777; GO:0005778; GO:0005829; GO:0005886; GO:0006909; GO:0008021; GO:0014059; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030670; GO:0030672; GO:0031045; GO:0032009; GO:0036465; GO:0042734; GO:0042995; GO:0045956; GO:0046850; GO:0048791; GO:0050764; GO:0050796; GO:0070062; GO:0070092; GO:0070382; GO:0071277; GO:0090119; GO:0090385; GO:0098686; GO:1900242; GO:1990926; GO:1990927 14847 FUN_000917 0 13 0 29 27 NA NA NA NA NA NA NA 14848 FUN_000914 2318 1441 886 611 633 NA NA NA NA NA NA NA 14849 FUN_000915 1630 1482 500 733 299 NA NA NA NA NA NA NA 14850 FUN_000912 826 325 408 474 589 ntLink_6:5966537-5973579 Q5RCQ9 1.49e-32 Kelch-like protein 23 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 14851 FUN_000913 613 327 137 119 45 NA NA NA NA NA NA NA 14852 FUN_000910 730 424 418 757 848 ntLink_6:5950688-5955408 P21521 1.03e-27 Synaptotagmin 1 (p65) Drosophila melanogaster (Fruit fly) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; larval locomotory behavior [GO:0008345]; neurotransmitter secretion [GO:0007269]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of pole plasm oskar mRNA localization [GO:0007317]; regulation of synapse structure or activity [GO:0050803]; rhythmic synaptic transmission [GO:0060024]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0007268; GO:0007269; GO:0007317; GO:0008021; GO:0008345; GO:0014059; GO:0016020; GO:0016079; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030424; GO:0030672; GO:0031045; GO:0031340; GO:0031594; GO:0042803; GO:0043195; GO:0048488; GO:0048791; GO:0050803; GO:0060024; GO:0070382; GO:0071277; GO:0150007; GO:1900073 14853 FUN_000910 730 424 418 757 848 ntLink_6:5950688-5955408 P21521 2.27e-22 Synaptotagmin 1 (p65) Drosophila melanogaster (Fruit fly) calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cellular response to calcium ion [GO:0071277]; chemical synaptic transmission [GO:0007268]; clathrin-dependent synaptic vesicle endocytosis [GO:0150007]; larval locomotory behavior [GO:0008345]; neurotransmitter secretion [GO:0007269]; positive regulation of vesicle fusion [GO:0031340]; regulation of calcium ion-dependent exocytosis [GO:0017158]; regulation of dopamine secretion [GO:0014059]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of pole plasm oskar mRNA localization [GO:0007317]; regulation of synapse structure or activity [GO:0050803]; rhythmic synaptic transmission [GO:0060024]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle exocytosis [GO:0016079]; vesicle-mediated transport [GO:0016192] GO:0000149; GO:0001786; GO:0005509; GO:0005544; GO:0005886; GO:0007268; GO:0007269; GO:0007317; GO:0008021; GO:0008345; GO:0014059; GO:0016020; GO:0016079; GO:0016192; GO:0017156; GO:0017158; GO:0019905; GO:0030276; GO:0030424; GO:0030672; GO:0031045; GO:0031340; GO:0031594; GO:0042803; GO:0043195; GO:0048488; GO:0048791; GO:0050803; GO:0060024; GO:0070382; GO:0071277; GO:0150007; GO:1900073 14854 FUN_000911 33 23 40 41 51 NA NA NA NA NA NA NA 14855 FUN_000918 353 753 292 1154 212 NA NA NA NA NA NA NA 14856 FUN_000919 78 298 186 40 36 NA NA NA NA NA NA NA 14857 FUN_009768 25 34 16 25 29 NA NA NA NA NA NA NA 14858 FUN_009769 263 87 227 237 172 ptg000004l:11330280-11332281 O15973 2.19e-46 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 14859 FUN_009766 394 288 258 259 342 NA NA NA NA NA NA NA 14860 FUN_009767 718 417 253 286 250 NA NA NA NA NA NA NA 14861 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 3.89e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14862 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 4.62e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14863 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 5.42e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14864 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 5.78e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14865 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 3.89e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14866 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 4.37e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14867 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 8.86e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14868 FUN_009764 793 673 483 1540 1063 ptg000004l:11280773-11314629 Q96AY4 1.15e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14869 FUN_009765 1906 3363 1620 1755 1349 NA NA NA NA NA NA NA 14870 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.28e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14871 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.71e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14872 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 5.21e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14873 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.59e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14874 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.17e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14875 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 5.6e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14876 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.67e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14877 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.47e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14878 FUN_009762 261 104 423 367 365 ptg000004l:11234576-11262865 Q96AY4 1.5e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14879 FUN_009763 152 217 88 179 205 ptg000004l:11274024-11278146 Q96AY4 3.43e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14880 FUN_009763 152 217 88 179 205 ptg000004l:11274024-11278146 Q96AY4 5.53e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14881 FUN_009763 152 217 88 179 205 ptg000004l:11274024-11278146 Q96AY4 3.82e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14882 FUN_009763 152 217 88 179 205 ptg000004l:11274024-11278146 Q96AY4 4.14e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14883 FUN_009763 152 217 88 179 205 ptg000004l:11274024-11278146 Q96AY4 6.6e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14884 FUN_009763 152 217 88 179 205 ptg000004l:11274024-11278146 Q96AY4 6.93e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14885 FUN_012588 542 347 351 373 420 NA NA NA NA NA NA NA 14886 FUN_007337 2019 3407 1042 2436 2052 ptg000002l:1504774-1542867 P34457 1.24e-28 Putative uncharacterized transposon-derived protein F54H12.3 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0015074 14887 FUN_012583 31 0 0 0 0 NA NA NA NA NA NA NA 14888 FUN_012580 50 0 26 63 0 ptg000008l:10085016-10088197 Q7Z442 1.58e-32 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 14889 FUN_012586 99 10 30 62 54 NA NA NA NA NA NA NA 14890 FUN_012587 123 204 60 248 81 NA NA NA NA NA NA NA 14891 FUN_012585 303 59 72 241 81 NA NA NA NA NA NA NA 14892 FUN_029665 4753 4103 3011 6254 3882 ptg000023l:4227354-4249983 Q6DIC0 9.32e-27 Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2) Mus musculus (Mouse) aortic smooth muscle cell differentiation [GO:0035887]; cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; fibroblast proliferation [GO:0048144]; hematopoietic stem cell homeostasis [GO:0061484]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast proliferation [GO:0048147]; nervous system development [GO:0007399]; nucleosome assembly [GO:0006334]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000976; GO:0003677; GO:0003682; GO:0003713; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0006325; GO:0006334; GO:0006338; GO:0006357; GO:0007399; GO:0008094; GO:0008283; GO:0008284; GO:0008285; GO:0016514; GO:0016787; GO:0030071; GO:0030308; GO:0035060; GO:0035887; GO:0042393; GO:0043231; GO:0045111; GO:0045582; GO:0045596; GO:0045597; GO:0045663; GO:0045892; GO:0045893; GO:0045944; GO:0048144; GO:0048147; GO:0061484; GO:0070316; GO:0071564; GO:0071565; GO:0140092; GO:0140288; GO:0140658; GO:1902459; GO:2000045; GO:2000781; GO:2000819 14893 FUN_029665 4753 4103 3011 6254 3882 ptg000023l:4227354-4249983 Q6DIC0 2.31e-22 Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2) Mus musculus (Mouse) aortic smooth muscle cell differentiation [GO:0035887]; cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; fibroblast proliferation [GO:0048144]; hematopoietic stem cell homeostasis [GO:0061484]; negative regulation of cell differentiation [GO:0045596]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fibroblast proliferation [GO:0048147]; nervous system development [GO:0007399]; nucleosome assembly [GO:0006334]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair [GO:2000781]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of stem cell population maintenance [GO:1902459]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of G0 to G1 transition [GO:0070316]; regulation of G1/S transition of mitotic cell cycle [GO:2000045]; regulation of mitotic metaphase/anaphase transition [GO:0030071]; regulation of nucleotide-excision repair [GO:2000819]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000976; GO:0003677; GO:0003682; GO:0003713; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0006325; GO:0006334; GO:0006338; GO:0006357; GO:0007399; GO:0008094; GO:0008283; GO:0008284; GO:0008285; GO:0016514; GO:0016787; GO:0030071; GO:0030308; GO:0035060; GO:0035887; GO:0042393; GO:0043231; GO:0045111; GO:0045582; GO:0045596; GO:0045597; GO:0045663; GO:0045892; GO:0045893; GO:0045944; GO:0048144; GO:0048147; GO:0061484; GO:0070316; GO:0071564; GO:0071565; GO:0140092; GO:0140288; GO:0140658; GO:1902459; GO:2000045; GO:2000781; GO:2000819 14894 FUN_029664 3201 1821 1584 2869 2374 NA NA NA NA NA NA NA 14895 FUN_016298 548 304 375 349 608 NA NA NA NA NA NA NA 14896 FUN_016299 5434 2602 2063 4737 2762 NA NA NA NA NA NA NA 14897 FUN_029660 24 28 29 65 152 ptg000023l:4207915-4211065 E7FAM5 6.36e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 14898 FUN_029662 90 183 87 58 68 NA NA NA NA NA NA NA 14899 FUN_016292 6159 4251 3454 5544 6420 NA NA NA NA NA NA NA 14900 FUN_016293 0 0 6 0 0 NA NA NA NA NA NA NA 14901 FUN_016290 1338 1019 453 900 1052 NA NA NA NA NA NA NA 14902 FUN_029669 268 1071 401 121 726 NA NA NA NA NA NA NA 14903 FUN_016297 9022 7269 4509 8433 6003 ptg000011l:1279654-1290374 P35224 4.24e-56 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 14904 FUN_016297 9022 7269 4509 8433 6003 ptg000011l:1279654-1290374 P35224 3.82e-35 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 14905 FUN_016297 9022 7269 4509 8433 6003 ptg000011l:1279654-1290374 P35224 2.28e-31 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 14906 FUN_016297 9022 7269 4509 8433 6003 ptg000011l:1279654-1290374 P35224 3.69e-29 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 14907 FUN_016297 9022 7269 4509 8433 6003 ptg000011l:1279654-1290374 P35224 6.74e-22 Catenin beta (Beta-catenin) Urechis caupo (Innkeeper worm) (Spoonworm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0007155; GO:0045296 14908 FUN_016294 452 216 237 258 250 NA NA NA NA NA NA NA 14909 FUN_016295 65 0 0 24 40 NA NA NA NA NA NA NA 14910 FUN_007336 30 87 28 56 39 NA NA NA NA NA NA NA 14911 FUN_015753 0 8 11 16 30 NA NA NA NA NA NA NA 14912 FUN_010988 3700 2215 1767 2895 2823 NA NA NA NA NA NA NA 14913 FUN_010989 27 28 15 22 17 NA NA NA NA NA NA NA 14914 FUN_015754 0 6 5 34 8 NA NA NA NA NA NA NA 14915 FUN_010984 1474 442 557 1126 954 NA NA NA NA NA NA NA 14916 FUN_010985 525 409 289 545 723 ptg000007l:5246992-5259537 E1C2V1 1.38e-25 Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog) Gallus gallus (Chicken) chromatin organization [GO:0006325]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003682; GO:0005634; GO:0006325; GO:0008270; GO:0035064; GO:0042393; GO:0045892 14917 FUN_010987 864 350 311 469 411 NA NA NA NA NA NA NA 14918 FUN_010980 292 166 143 101 99 NA NA NA NA NA NA NA 14919 FUN_010981 692 1378 584 773 1006 NA NA NA NA NA NA NA 14920 FUN_010982 6336 9180 3283 4508 3627 NA NA NA NA NA NA NA 14921 FUN_010983 1825 2976 932 1363 805 NA NA NA NA NA NA NA 14922 FUN_016128 387 189 196 157 586 NA NA NA NA NA NA NA 14923 FUN_016126 112 267 219 360 327 ptg000010l:1881816-1885829 Q90W33 4.5e-23 Hypermethylated in cancer 2 protein Danio rerio (Zebrafish) (Brachydanio rerio) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 14924 FUN_016127 5736 6792 4200 7215 3555 NA NA NA NA NA NA NA 14925 FUN_016121 3249 1460 722 2384 796 NA NA NA NA NA NA NA 14926 FUN_016122 2849 2549 1571 3807 4826 NA NA NA NA NA NA NA 14927 FUN_016123 325 167 97 193 427 NA NA NA NA NA NA NA 14928 FUN_009188 187 282 106 106 80 ptg000004l:3713204-3718490 Q96AY4 1.28e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14929 FUN_009188 187 282 106 106 80 ptg000004l:3713204-3718490 Q96AY4 6.19e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14930 FUN_009188 187 282 106 106 80 ptg000004l:3713204-3718490 Q96AY4 3.16e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14931 FUN_009188 187 282 106 106 80 ptg000004l:3713204-3718490 Q96AY4 7.14e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14932 FUN_009189 46 91 72 33 82 NA NA NA NA NA NA NA 14933 FUN_009183 42 40 69 34 3 ptg000004l:3645882-3652680 Q96AY4 6.2e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14934 FUN_009183 42 40 69 34 3 ptg000004l:3645882-3652680 Q96AY4 9.73e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14935 FUN_009183 42 40 69 34 3 ptg000004l:3645882-3652680 Q96AY4 5.53e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14936 FUN_009183 42 40 69 34 3 ptg000004l:3645882-3652680 Q96AY4 1.19e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14937 FUN_009183 42 40 69 34 3 ptg000004l:3645882-3652680 Q96AY4 4.07e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14938 FUN_009180 6 1 3 3 1 NA NA NA NA NA NA NA 14939 FUN_009186 30 84 40 11 13 NA NA NA NA NA NA NA 14940 FUN_009187 40 180 91 22 17 ptg000004l:3690399-3694392 Q96AY4 1.26e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14941 FUN_009187 40 180 91 22 17 ptg000004l:3690399-3694392 Q96AY4 1.46e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14942 FUN_009187 40 180 91 22 17 ptg000004l:3690399-3694392 Q96AY4 2.82e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14943 FUN_009187 40 180 91 22 17 ptg000004l:3690399-3694392 Q96AY4 2.5e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14944 FUN_009187 40 180 91 22 17 ptg000004l:3690399-3694392 Q96AY4 1.97e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 14945 FUN_009184 33 12 35 0 26 NA NA NA NA NA NA NA 14946 FUN_009185 0 20 24 34 66 NA NA NA NA NA NA NA 14947 FUN_026559 0 1 7 0 16 NA NA NA NA NA NA NA 14948 FUN_026556 1256 629 563 1128 1072 NA NA NA NA NA NA NA 14949 FUN_023701 3867 3643 2775 3583 2039 ptg000017l:10764044-10772917 Q8BQB6 4.77e-29 Stabilizer of axonemal microtubules 2 Mus musculus (Mouse) NA GO:0005634; GO:0005814; GO:0005856; GO:0005879; GO:0008017; GO:0036064; GO:0036126 14950 FUN_017284 0 0 0 0 6 NA NA NA NA NA NA NA 14951 FUN_023706 3 0 7 22 7 NA NA NA NA NA NA NA 14952 FUN_022078 225 186 129 212 63 NA NA NA NA NA NA NA 14953 FUN_001651 884 686 900 858 615 ntLink_6:14603029-14605920 P19971 1.25e-34 Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase) Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; dTMP catabolic process [GO:0046074]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969] GO:0000002; GO:0001525; GO:0004645; GO:0005829; GO:0006206; GO:0006213; GO:0006935; GO:0008083; GO:0009032; GO:0016154; GO:0030154; GO:0031641; GO:0042803; GO:0046074; GO:0051969; GO:1905333 14954 FUN_022071 494 153 219 413 412 ptg000016l:5217482-5221642 P18700 1.29e-49 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 14955 FUN_022071 494 153 219 413 412 ptg000016l:5217482-5221642 P18700 7.79e-41 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 14956 FUN_022071 494 153 219 413 412 ptg000016l:5217482-5221642 P18700 6.29e-40 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 14957 FUN_022070 121 85 102 151 310 NA NA NA NA NA NA NA 14958 FUN_022073 399 256 116 151 203 NA NA NA NA NA NA NA 14959 FUN_022072 1240 1210 733 1255 1115 NA NA NA NA NA NA NA 14960 FUN_022075 3638 1967 1128 2224 1370 NA NA NA NA NA NA NA 14961 FUN_022074 157 239 70 19 158 NA NA NA NA NA NA NA 14962 FUN_022076 4348 3689 2114 3615 3576 NA NA NA NA NA NA NA 14963 FUN_017989 441 572 454 1260 491 ptg000012l:2817190-2826177 Q8R151 4.92e-176 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 14964 FUN_017989 441 572 454 1260 491 ptg000012l:2817190-2826177 Q8R151 1.99e-76 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 14965 FUN_017989 441 572 454 1260 491 ptg000012l:2817190-2826177 Q8R151 3.29e-26 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 14966 FUN_017988 148 471 225 243 61 ptg000012l:2804503-2810210 Q8R151 1.7e-179 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 14967 FUN_017988 148 471 225 243 61 ptg000012l:2804503-2810210 Q8R151 1.44e-25 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 14968 FUN_017985 123 128 26 134 156 NA NA NA NA NA NA NA 14969 FUN_017984 34 0 0 30 9 NA NA NA NA NA NA NA 14970 FUN_017987 41 177 46 84 7 ptg000012l:2800379-2803383 Q8R151 6.74e-76 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 14971 FUN_017986 2429 2744 1529 1898 1544 NA NA NA NA NA NA NA 14972 FUN_017981 159 39 25 19 37 NA NA NA NA NA NA NA 14973 FUN_017980 0 0 41 0 11 NA NA NA NA NA NA NA 14974 FUN_024950 3 0 0 0 12 NA NA NA NA NA NA NA 14975 FUN_042599 26 8 0 23 45 NA NA NA NA NA NA NA 14976 FUN_025391 0 0 45 0 32 ptg000019l:2182266-2186061 O00370 2.73e-28 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 14977 FUN_025390 0 3 0 0 27 NA NA NA NA NA NA NA 14978 FUN_025393 754 533 673 822 713 ptg000019l:2192573-2194340 P98070 1.48e-40 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 14979 FUN_025393 754 533 673 822 713 ptg000019l:2192573-2194340 P98070 3.47e-28 Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.-) Xenopus laevis (African clawed frog) cartilage development [GO:0051216]; cell differentiation [GO:0030154]; ossification [GO:0001503]; proteolysis [GO:0006508] GO:0001503; GO:0004222; GO:0005125; GO:0005509; GO:0005615; GO:0005794; GO:0006508; GO:0008083; GO:0008270; GO:0030154; GO:0051216 14980 FUN_025392 2126 2611 1401 1265 2345 ptg000019l:2187635-2190134 P97864 3.53e-51 Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11] Mus musculus (Mouse) apoptotic process [GO:0006915]; cellular response to staurosporine [GO:0072734]; defense response to bacterium [GO:0042742]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; fibroblast apoptotic process [GO:0044346]; heart development [GO:0007507]; inflammatory response [GO:0006954]; intracellular signal transduction [GO:0035556]; intrinsic apoptotic signaling pathway [GO:0097193]; lymphocyte apoptotic process [GO:0070227]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of plasma membrane repair [GO:1905686]; protein catabolic process [GO:0030163]; protein processing [GO:0016485]; proteolysis [GO:0006508]; response to UV [GO:0009411] GO:0003723; GO:0004190; GO:0004197; GO:0005615; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006954; GO:0007507; GO:0008233; GO:0008234; GO:0008303; GO:0009411; GO:0016485; GO:0030163; GO:0035556; GO:0042742; GO:0043065; GO:0043231; GO:0044346; GO:0051402; GO:0070227; GO:0072734; GO:0097153; GO:0097191; GO:0097193; GO:0097194; GO:0097200; GO:1905686 14981 FUN_025395 65 135 113 181 151 NA NA NA NA NA NA NA 14982 FUN_025394 564 446 319 1349 479 NA NA NA NA NA NA NA 14983 FUN_025397 56 183 334 216 333 ptg000019l:2227964-2229302 Q2LE78 3.19e-89 BTB/POZ domain-containing protein 6 Xenopus laevis (African clawed frog) NA GO:0005737 14984 FUN_025399 29 66 26 138 67 NA NA NA NA NA NA NA 14985 FUN_014188 0 0 14 0 6 NA NA NA NA NA NA NA 14986 FUN_014189 0 21 0 0 0 NA NA NA NA NA NA NA 14987 FUN_014180 1170 899 73 44 0 NA NA NA NA NA NA NA 14988 FUN_014181 104 6 0 128 2 NA NA NA NA NA NA NA 14989 FUN_014184 332 280 128 46 205 NA NA NA NA NA NA NA 14990 FUN_014185 447 12 20 585 6 NA NA NA NA NA NA NA 14991 FUN_014186 0 0 0 6 0 NA NA NA NA NA NA NA 14992 FUN_014187 35 41 43 62 67 NA NA NA NA NA NA NA 14993 FUN_043242 21696 11008 13423 23826 19461 NA NA NA NA NA NA NA 14994 FUN_007043 0 0 0 21 12 NA NA NA NA NA NA NA 14995 FUN_044334 6 0 0 1 0 NA NA NA NA NA NA NA 14996 FUN_043240 2244 2093 662 1061 452 NA NA NA NA NA NA NA 14997 FUN_007045 11 0 9 51 15 NA NA NA NA NA NA NA 14998 FUN_007044 89 17 65 101 17 NA NA NA NA NA NA NA 14999 FUN_007047 554 227 172 234 281 NA NA NA NA NA NA NA 15000 FUN_007046 0 0 11 0 0 NA NA NA NA NA NA NA 15001 FUN_019463 4 0 25 82 48 NA NA NA NA NA NA NA 15002 FUN_019465 8 0 55 0 78 NA NA NA NA NA NA NA 15003 FUN_030025 13 1 0 41 6 NA NA NA NA NA NA NA 15004 FUN_019469 4 0 2 62 22 NA NA NA NA NA NA NA 15005 FUN_030026 7 0 0 0 0 NA NA NA NA NA NA NA 15006 FUN_038230 135 47 40 68 246 ptg000027l:4499595-4502268 Q6IVV8 4.22e-47 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 15007 FUN_038231 0 0 65 25 10 NA NA NA NA NA NA NA 15008 FUN_038232 0 71 68 102 58 NA NA NA NA NA NA NA 15009 FUN_038233 42 44 82 69 174 NA NA NA NA NA NA NA 15010 FUN_038234 1228 691 418 828 771 NA NA NA NA NA NA NA 15011 FUN_038235 453 242 302 246 253 NA NA NA NA NA NA NA 15012 FUN_038236 919 851 313 949 884 NA NA NA NA NA NA NA 15013 FUN_038237 74 0 29 32 12 NA NA NA NA NA NA NA 15014 FUN_038238 1743 1118 772 925 770 NA NA NA NA NA NA NA 15015 FUN_038239 42 0 0 0 0 NA NA NA NA NA NA NA 15016 FUN_039541 0 0 0 16 20 NA NA NA NA NA NA NA 15017 FUN_039540 0 0 8 0 10 NA NA NA NA NA NA NA 15018 FUN_039543 0 0 10 0 130 NA NA NA NA NA NA NA 15019 FUN_039542 0 0 6 0 4 NA NA NA NA NA NA NA 15020 FUN_039546 7 0 22 0 12 NA NA NA NA NA NA NA 15021 FUN_024046 380 183 160 184 72 NA NA NA NA NA NA NA 15022 FUN_024047 339 380 157 81 84 ptg000018l:1696879-1701512 Q99MB5 5.79e-24 LIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) Rattus norvegicus (Rat) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of T cell homeostatic proliferation [GO:0046013] GO:0000122; GO:0003713; GO:0005634; GO:0045944; GO:0046013; GO:0046872; GO:0140297 15023 FUN_024044 287 231 205 334 252 ptg000018l:1674613-1690016 P04274 3.47e-25 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mesocricetus auratus (Golden hamster) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 15024 FUN_024042 2 51 36 34 73 NA NA NA NA NA NA NA 15025 FUN_024043 3786 2847 2014 2676 1895 ptg000018l:1660997-1665241 Q5T0T0 1.73e-45 E3 ubiquitin-protein ligase MARCHF8 (EC 2.3.2.27) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING finger protein 178) (RING-type E3 ubiquitin transferase MARCHF8) Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; immune response [GO:0006955]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0002250; GO:0002495; GO:0004842; GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0006955; GO:0008270; GO:0031901; GO:0031902; GO:0042287; GO:0061630 15026 FUN_024043 3786 2847 2014 2676 1895 ptg000018l:1660997-1665241 Q5T0T0 2.72e-23 E3 ubiquitin-protein ligase MARCHF8 (EC 2.3.2.27) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING finger protein 178) (RING-type E3 ubiquitin transferase MARCHF8) Homo sapiens (Human) adaptive immune response [GO:0002250]; antigen processing and presentation of peptide antigen via MHC class II [GO:0002495]; immune response [GO:0006955]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0002250; GO:0002495; GO:0004842; GO:0005737; GO:0005764; GO:0005765; GO:0005768; GO:0006955; GO:0008270; GO:0031901; GO:0031902; GO:0042287; GO:0061630 15027 FUN_024040 152 61 112 214 227 NA NA NA NA NA NA NA 15028 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 2.07e-35 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15029 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 3.73e-33 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15030 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 4.17e-33 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15031 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 1.33e-28 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15032 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 3.06e-28 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15033 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 8.64e-25 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15034 FUN_024041 11666 10803 5160 10144 9117 ptg000018l:1612731-1626879 P11024 9.96e-24 NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase) Bos taurus (Bovine) NADPH regeneration [GO:0006740]; proton transmembrane transport [GO:1902600]; reactive oxygen species metabolic process [GO:0072593] GO:0005743; GO:0006740; GO:0008746; GO:0050661; GO:0051287; GO:0072593; GO:1902600 15035 FUN_024048 2394 2769 1122 856 617 NA NA NA NA NA NA NA 15036 FUN_014871 4653 6058 4187 6558 2907 NA NA NA NA NA NA NA 15037 FUN_027632 0 0 0 28 0 NA NA NA NA NA NA NA 15038 FUN_027634 72 262 56 187 9 NA NA NA NA NA NA NA 15039 FUN_027635 0 8 2 0 0 NA NA NA NA NA NA NA 15040 FUN_013110 9 10 12 11 8 NA NA NA NA NA NA NA 15041 FUN_013111 123 275 43 227 45 NA NA NA NA NA NA NA 15042 FUN_038498 2248 2246 1570 1741 1812 NA NA NA NA NA NA NA 15043 FUN_038499 102 108 55 76 90 NA NA NA NA NA NA NA 15044 FUN_038494 0 99 0 42 0 NA NA NA NA NA NA NA 15045 FUN_038496 1054 1341 1002 1363 916 NA NA NA NA NA NA NA 15046 FUN_038497 5104 4537 3001 1402 2366 NA NA NA NA NA NA NA 15047 FUN_038490 1216 1384 1417 212 3149 NA NA NA NA NA NA NA 15048 FUN_038491 295 162 70 160 297 NA NA NA NA NA NA NA 15049 FUN_038492 9 15 24 21 18 NA NA NA NA NA NA NA 15050 FUN_013117 27 42 25 40 45 NA NA NA NA NA NA NA 15051 FUN_031772 0 0 8 0 0 NA NA NA NA NA NA NA 15052 FUN_031773 0 0 82 0 0 NA NA NA NA NA NA NA 15053 FUN_031771 0 0 78 0 0 NA NA NA NA NA NA NA 15054 FUN_031777 0 0 1636 4 0 NA NA NA NA NA NA NA 15055 FUN_031774 0 0 111 0 0 NA NA NA NA NA NA NA 15056 FUN_031778 0 25 12 0 0 NA NA NA NA NA NA NA 15057 FUN_031779 0 97 46 0 0 NA NA NA NA NA NA NA 15058 FUN_029234 176 262 245 483 192 NA NA NA NA NA NA NA 15059 FUN_014874 12 0 21 20 35 NA NA NA NA NA NA NA 15060 FUN_014875 2408 2293 1224 2371 1302 NA NA NA NA NA NA NA 15061 FUN_027098 5 0 0 21 26 NA NA NA NA NA NA NA 15062 FUN_027099 2 0 0 0 68 NA NA NA NA NA NA NA 15063 FUN_027094 0 19 4 0 0 NA NA NA NA NA NA NA 15064 FUN_027095 0 0 0 0 88 NA NA NA NA NA NA NA 15065 FUN_027096 0 0 0 0 53 NA NA NA NA NA NA NA 15066 FUN_027097 0 10 0 0 15 NA NA NA NA NA NA NA 15067 FUN_014876 892 926 744 1051 747 ptg000009l:3859448-3861457 Q5F3N1 5.93e-27 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) Gallus gallus (Chicken) protein methylation [GO:0006479] GO:0004719; GO:0005737; GO:0005829; GO:0006479 15068 FUN_014876 892 926 744 1051 747 ptg000009l:3859448-3861457 Q5F3N1 1.34e-23 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT) (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl/D-aspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) Gallus gallus (Chicken) protein methylation [GO:0006479] GO:0004719; GO:0005737; GO:0005829; GO:0006479 15069 FUN_026940 165 32 8 125 41 NA NA NA NA NA NA NA 15070 FUN_026949 0 0 0 0 16 NA NA NA NA NA NA NA 15071 FUN_029231 3 0 26 0 0 NA NA NA NA NA NA NA 15072 FUN_011111 0 0 14 19 51 NA NA NA NA NA NA NA 15073 FUN_011112 1 0 0 0 68 NA NA NA NA NA NA NA 15074 FUN_037329 28137 37719 12589 20488 13065 NA NA NA NA NA NA NA 15075 FUN_002607 3 0 53 8 0 NA NA NA NA NA NA NA 15076 FUN_037323 1419 334 476 1400 574 NA NA NA NA NA NA NA 15077 FUN_037322 103 111 119 197 195 NA NA NA NA NA NA NA 15078 FUN_037321 2036 1811 1104 1628 1369 NA NA NA NA NA NA NA 15079 FUN_037320 1684 1062 1047 1801 1044 NA NA NA NA NA NA NA 15080 FUN_037327 3947 2814 1070 2536 3212 NA NA NA NA NA NA NA 15081 FUN_037325 2687 2134 1503 3041 2894 NA NA NA NA NA NA NA 15082 FUN_037324 1272 522 589 875 1028 ptg000026l:8759761-8773587 Q96JH7 8.42e-152 Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; endoplasmic reticulum membrane fusion [GO:0016320]; Golgi reassembly [GO:0090168]; mitotic cell cycle [GO:0000278]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; regulation of protein localization to chromatin [GO:1905634] GO:0000278; GO:0004843; GO:0005634; GO:0005737; GO:0005788; GO:0005795; GO:0006974; GO:0016320; GO:0016567; GO:0016579; GO:0035871; GO:0071108; GO:0090168; GO:0106300; GO:1905634 15083 FUN_037324 1272 522 589 875 1028 ptg000026l:8759761-8773587 Q96JH7 7.85e-22 Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; endoplasmic reticulum membrane fusion [GO:0016320]; Golgi reassembly [GO:0090168]; mitotic cell cycle [GO:0000278]; protein deubiquitination [GO:0016579]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein ubiquitination [GO:0016567]; protein-DNA covalent cross-linking repair [GO:0106300]; regulation of protein localization to chromatin [GO:1905634] GO:0000278; GO:0004843; GO:0005634; GO:0005737; GO:0005788; GO:0005795; GO:0006974; GO:0016320; GO:0016567; GO:0016579; GO:0035871; GO:0071108; GO:0090168; GO:0106300; GO:1905634 15084 FUN_011116 20 10 5 4 0 NA NA NA NA NA NA NA 15085 FUN_011117 5 11 5 0 5 NA NA NA NA NA NA NA 15086 FUN_001579 146 59 58 188 29 NA NA NA NA NA NA NA 15087 FUN_001578 1813 1693 1137 2023 1977 ntLink_6:13948005-13976407 Q75WS4 0 Cryptochrome DASH Xenopus laevis (African clawed frog) DNA repair [GO:0006281] GO:0003913; GO:0006281 15088 FUN_001577 1510 742 544 812 761 NA NA NA NA NA NA NA 15089 FUN_008268 190 109 62 104 87 NA NA NA NA NA NA NA 15090 FUN_008269 1389 585 721 1325 1388 NA NA NA NA NA NA NA 15091 FUN_035131 882 413 373 1012 448 ptg000025l:4329351-4338994 Q149M9 1.6e-48 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 15092 FUN_019464 0 0 6 0 16 NA NA NA NA NA NA NA 15093 FUN_035132 16 23 17 41 36 ptg000025l:4340207-4342641 Q4GZT3 5.33e-21 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 15094 FUN_030321 5 0 7 0 22 ptg000023l:10604472-10605235 P84239 1.14e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15095 FUN_035136 1 4 0 17 0 NA NA NA NA NA NA NA 15096 FUN_035137 1515 126 122 173 148 ptg000025l:4389751-4391713 Q8K3Z0 5.66e-29 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 15097 FUN_005020 631 427 313 608 471 NA NA NA NA NA NA NA 15098 FUN_041086 36 4 5 3 16 NA NA NA NA NA NA NA 15099 FUN_007809 6 0 0 0 11 NA NA NA NA NA NA NA 15100 FUN_007808 431 347 280 519 536 NA NA NA NA NA NA NA 15101 FUN_007805 0 6 0 8 0 NA NA NA NA NA NA NA 15102 FUN_007804 71 102 42 112 41 NA NA NA NA NA NA NA 15103 FUN_007807 449 406 291 151 269 ptg000002l:4963627-4965293 Q9UNW1 1.01e-55 Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) Homo sapiens (Human) bone mineralization [GO:0030282]; inositol phosphate metabolic process [GO:0043647]; ossification [GO:0001503]; polyphosphate metabolic process [GO:0006797] GO:0001503; GO:0003993; GO:0005783; GO:0005788; GO:0006797; GO:0030282; GO:0030351; GO:0034417; GO:0043647; GO:0051717; GO:0052745; GO:0052826; GO:0070062; GO:0101006 15104 FUN_007806 133 44 133 53 179 NA NA NA NA NA NA NA 15105 FUN_007801 3951 2977 2986 3737 4065 NA NA NA NA NA NA NA 15106 FUN_007800 1314 1662 685 1074 1178 NA NA NA NA NA NA NA 15107 FUN_007803 715 683 422 1001 283 ptg000002l:4934316-4951853 Q9Y468 1.38e-23 Lethal(3)malignant brain tumor-like protein 1 (H-l(3)mbt) (H-l(3)mbt protein) (L(3)mbt-like) (L(3)mbt protein homolog) (L3MBTL1) Homo sapiens (Human) chromatin organization [GO:0006325]; hemopoiesis [GO:0030097]; heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892]; regulation of cell cycle [GO:0051726]; regulation of megakaryocyte differentiation [GO:0045652]; regulation of mitotic nuclear division [GO:0007088] GO:0000785; GO:0000793; GO:0003682; GO:0005634; GO:0005654; GO:0006325; GO:0007088; GO:0008270; GO:0030097; GO:0031491; GO:0031507; GO:0032093; GO:0035064; GO:0042393; GO:0042802; GO:0045652; GO:0045892; GO:0051726; GO:0061793 15108 FUN_007802 201 349 132 425 165 NA NA NA NA NA NA NA 15109 FUN_041648 683 486 220 725 317 ptg000035l:6180239-6181589 Q504A5 1.21e-22 Probable thiopurine S-methyltransferase (Thiopurine methyltransferase) (EC 2.1.1.67) Danio rerio (Zebrafish) (Brachydanio rerio) methylation [GO:0032259] GO:0005737; GO:0008119; GO:0032259 15110 FUN_019058 13 26 13 7 32 NA NA NA NA NA NA NA 15111 FUN_018478 326 284 178 508 368 NA NA NA NA NA NA NA 15112 FUN_034009 97 47 104 168 45 ptg000024l:3659619-3663808 P46023 4.61e-82 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 15113 FUN_034008 33 28 14 109 62 NA NA NA NA NA NA NA 15114 FUN_018470 977 645 182 582 627 NA NA NA NA NA NA NA 15115 FUN_034000 6843 4936 3140 2989 4641 NA NA NA NA NA NA NA 15116 FUN_018474 159 206 137 389 255 NA NA NA NA NA NA NA 15117 FUN_018475 1781 1339 299 2831 1780 NA NA NA NA NA NA NA 15118 FUN_018476 2462 4339 1924 6703 3496 NA NA NA NA NA NA NA 15119 FUN_018477 1315 1638 350 1103 811 ptg000012l:9909035-9925106 P04323 1.52e-58 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 15120 FUN_044143 0 0 0 0 6 NA NA NA NA NA NA NA 15121 FUN_007113 55 0 0 38 164 NA NA NA NA NA NA NA 15122 FUN_007112 992 124 75 466 1163 NA NA NA NA NA NA NA 15123 FUN_007111 1366 633 323 676 923 NA NA NA NA NA NA NA 15124 FUN_007117 1012 562 387 738 770 NA NA NA NA NA NA NA 15125 FUN_043318 1027 323 738 1297 1110 NA NA NA NA NA NA NA 15126 FUN_007115 2387 1081 1072 1535 2146 NA NA NA NA NA NA NA 15127 FUN_007114 0 0 0 23 0 NA NA NA NA NA NA NA 15128 FUN_043315 201 81 28 153 34 NA NA NA NA NA NA NA 15129 FUN_043314 479 118 124 335 576 NA NA NA NA NA NA NA 15130 FUN_043317 2513 1157 974 2815 2516 NA NA NA NA NA NA NA 15131 FUN_043316 151 108 54 186 123 ptg000047l:6947333-6949725 Q5U3Y0 8.61e-70 Kelch domain-containing protein 10 Rattus norvegicus (Rat) positive regulation of stress-activated MAPK cascade [GO:0032874]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0016567; GO:0031462; GO:0032874; GO:0140627; GO:1990756 15132 FUN_043311 1136 979 470 1324 743 ptg000047l:6891345-6895730 A9JS51 3.96e-24 Protein FAM166B Xenopus laevis (African clawed frog) NA GO:0005879 15133 FUN_043310 1028 538 494 695 921 NA NA NA NA NA NA NA 15134 FUN_043313 940 881 584 677 683 NA NA NA NA NA NA NA 15135 FUN_043312 900 443 716 617 964 NA NA NA NA NA NA NA 15136 FUN_005984 1 0 0 6 7 NA NA NA NA NA NA NA 15137 FUN_005985 359 244 52 319 105 NA NA NA NA NA NA NA 15138 FUN_005982 59 163 38 105 19 ptg000001l:6419359-6420367 C3ZQF9 1.46e-32 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 15139 FUN_005980 49 43 60 98 9 NA NA NA NA NA NA NA 15140 FUN_005989 119 199 186 0 239 ptg000001l:6497965-6505354 O16025 2.54e-37 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 15141 FUN_005989 119 199 186 0 239 ptg000001l:6497965-6505354 O16025 2.47e-35 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 15142 FUN_005989 119 199 186 0 239 ptg000001l:6497965-6505354 O16025 2.87e-31 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 15143 FUN_005989 119 199 186 0 239 ptg000001l:6497965-6505354 O16025 3.03e-31 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 15144 FUN_013347 110 59 128 75 125 NA NA NA NA NA NA NA 15145 FUN_013346 10 109 89 166 365 NA NA NA NA NA NA NA 15146 FUN_013345 0 0 0 0 11 NA NA NA NA NA NA NA 15147 FUN_041224 3 103 44 16 1 NA NA NA NA NA NA NA 15148 FUN_013342 465 368 173 496 1442 NA NA NA NA NA NA NA 15149 FUN_013340 1660 953 1032 1428 1270 NA NA NA NA NA NA NA 15150 FUN_041229 15 36 16 24 53 NA NA NA NA NA NA NA 15151 FUN_034919 2244 1476 1176 1986 2620 NA NA NA NA NA NA NA 15152 FUN_034918 145 468 277 295 394 ptg000025l:1775513-1777079 Q15650 4.18e-145 Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4) Homo sapiens (Human) intracellular estrogen receptor signaling pathway [GO:0030520]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of myoblast differentiation [GO:0045661]; rescue of stalled ribosome [GO:0072344]; ribosome disassembly [GO:0032790]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116]; toxin transport [GO:1901998] GO:0002020; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0006355; GO:0008270; GO:0016604; GO:0016922; GO:0019901; GO:0030331; GO:0030520; GO:0031594; GO:0032790; GO:0032991; GO:0035035; GO:0044389; GO:0045661; GO:0045893; GO:0072344; GO:0099053; GO:1901998; GO:1990116 15153 FUN_034911 1165 809 468 397 405 NA NA NA NA NA NA NA 15154 FUN_034910 644 1441 1538 2119 1265 NA NA NA NA NA NA NA 15155 FUN_034913 2027 1634 803 1653 1202 ptg000025l:1718729-1719566 Q21305 8.08e-33 Transcription factor sox-2 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron fate specification [GO:0048665]; regulation of DNA-templated transcription [GO:0006355] GO:0000977; GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0048665 15156 FUN_034912 2099 271 181 783 231 NA NA NA NA NA NA NA 15157 FUN_034914 4972 3209 2474 4311 2698 ptg000025l:1737013-1739281 B5X4H8 5.65e-87 Riboflavin transporter 2 (RFT2) Salmo salar (Atlantic salmon) NA GO:0005886; GO:0032217 15158 FUN_034917 3246 2303 2333 5888 2736 NA NA NA NA NA NA NA 15159 FUN_036513 795 1344 978 3231 2736 ptg000025l:19106385-19121628 Q61140 6.7e-26 Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; actin filament reorganization [GO:0090527]; antigen receptor-mediated signaling pathway [GO:0050851]; B cell receptor signaling pathway [GO:0050853]; cell adhesion [GO:0007155]; cell chemotaxis [GO:0060326]; cell migration [GO:0016477]; cellular response to endothelin [GO:1990859]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to nitric oxide [GO:0071732]; endothelin receptor signaling pathway [GO:0086100]; epidermal growth factor receptor signaling pathway [GO:0007173]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatocyte growth factor receptor signaling pathway [GO:0048012]; insulin receptor signaling pathway [GO:0008286]; integrin-mediated signaling pathway [GO:0007229]; negative regulation of substrate adhesion-dependent cell spreading [GO:1900025]; neurotrophin TRK receptor signaling pathway [GO:0048011]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of cell migration [GO:0030335]; positive regulation of endothelial cell migration [GO:0010595]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0001726; GO:0005737; GO:0005829; GO:0005886; GO:0005925; GO:0007015; GO:0007155; GO:0007169; GO:0007173; GO:0007186; GO:0007229; GO:0008286; GO:0010595; GO:0015629; GO:0016020; GO:0016477; GO:0017124; GO:0019901; GO:0019904; GO:0030027; GO:0030036; GO:0030335; GO:0030424; GO:0035729; GO:0045202; GO:0048008; GO:0048010; GO:0048011; GO:0048012; GO:0050851; GO:0050853; GO:0060326; GO:0071732; GO:0086100; GO:0090527; GO:1900025; GO:1990859 15160 FUN_036512 377 373 205 239 18 NA NA NA NA NA NA NA 15161 FUN_036511 943 579 619 714 480 ptg000025l:19088378-19090190 Q9CQ02 7.27e-66 COMM domain-containing protein 4 Mus musculus (Mouse) NA GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0043231 15162 FUN_032868 24 81 46 54 31 NA NA NA NA NA NA NA 15163 FUN_036516 31 0 0 0 4 NA NA NA NA NA NA NA 15164 FUN_036519 394 75 146 452 46 ptg000025l:19175388-19204272 P21328 2.33e-30 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 15165 FUN_002061 15 0 0 7 36 NA NA NA NA NA NA NA 15166 FUN_002062 37 0 9 8 29 NA NA NA NA NA NA NA 15167 FUN_002063 3 11 0 2 11 NA NA NA NA NA NA NA 15168 FUN_002064 0 0 10 0 0 NA NA NA NA NA NA NA 15169 FUN_002068 51 0 0 0 0 NA NA NA NA NA NA NA 15170 FUN_002069 21 14 15 0 11 NA NA NA NA NA NA NA 15171 FUN_042042 791 793 679 934 957 ptg000035l:10038967-10042911 Q28C88 2.24e-22 2-acylglycerol O-acyltransferase 1 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 1) (MGAT1) (Monoacylglycerol O-acyltransferase 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) glycerol metabolic process [GO:0006071]; triglyceride biosynthetic process [GO:0019432] GO:0003846; GO:0005789; GO:0006071; GO:0019432 15172 FUN_042043 1026 974 784 1176 1278 ptg000035l:10043053-10045629 Q5M8H5 6.08e-36 2-acylglycerol O-acyltransferase 2 (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 2) (MGAT2) (Monoacylglycerol O-acyltransferase 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) glycerol metabolic process [GO:0006071]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432] GO:0003846; GO:0005789; GO:0006071; GO:0006640; GO:0019432; GO:1990578 15173 FUN_042040 1406 435 703 1089 705 NA NA NA NA NA NA NA 15174 FUN_042041 1023 532 401 1079 708 NA NA NA NA NA NA NA 15175 FUN_042046 25 30 55 70 50 NA NA NA NA NA NA NA 15176 FUN_042047 799 396 325 673 712 NA NA NA NA NA NA NA 15177 FUN_042044 3938 5338 3342 3187 1375 ptg000035l:10046764-10048495 Q6P342 6.8e-27 Diacylglycerol O-acyltransferase 2 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) diacylglycerol biosynthetic process [GO:0006651]; glycerol metabolic process [GO:0006071]; monoacylglycerol biosynthetic process [GO:0006640]; triglyceride biosynthetic process [GO:0019432] GO:0004144; GO:0005789; GO:0005811; GO:0006071; GO:0006640; GO:0006651; GO:0019432; GO:0050252; GO:1990578 15178 FUN_042045 3093 5935 3468 3283 3185 NA NA NA NA NA NA NA 15179 FUN_042048 2032 1641 1060 1582 1229 ptg000035l:10065500-10072194 Q6UWJ1 1.76e-35 Transmembrane and coiled-coil domain-containing protein 3 (Putative LAG1-interacting protein) Homo sapiens (Human) NA GO:0015386; GO:0016020 15180 FUN_042049 8938 10480 5508 5615 4588 NA NA NA NA NA NA NA 15181 FUN_040576 0 0 0 0 14 NA NA NA NA NA NA NA 15182 FUN_040577 0 0 17 0 0 NA NA NA NA NA NA NA 15183 FUN_014283 0 0 0 0 6 NA NA NA NA NA NA NA 15184 FUN_042594 3548 4196 2790 2138 1463 ptg000039l:124057-124894 Q9D531 1.9e-43 Nucleoredoxin-like protein 2 (Rod-derived cone viability factor 2) (RdCVF2) Mus musculus (Mouse) photoreceptor cell maintenance [GO:0045494]; sensory perception of smell [GO:0007608]; visual perception [GO:0007601] GO:0007601; GO:0007608; GO:0045494 15185 FUN_042595 3089 2861 2424 2794 1656 ptg000039l:125025-126576 Q8T3X9 8.87e-22 Iron-sulfur cluster assembly 1 homolog, mitochondrial (Lethal (1) G0136) (Putative magnetoreceptor subunit MagR) Drosophila melanogaster (Fruit fly) iron-sulfur cluster assembly [GO:0016226]; protein maturation by iron-sulfur cluster transfer [GO:0097428]; response to magnetism [GO:0071000] GO:0005737; GO:0005739; GO:0016226; GO:0046872; GO:0051537; GO:0071000; GO:0097428 15186 FUN_042596 1263 750 658 1255 1129 ptg000039l:129638-138111 Q0DB53 1.19e-32 DEAD-box ATP-dependent RNA helicase 52A (EC 3.6.4.13) Oryza sativa subsp. japonica (Rice) NA GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0016887 15187 FUN_042596 1263 750 658 1255 1129 ptg000039l:129638-138111 Q0DB53 3.57e-24 DEAD-box ATP-dependent RNA helicase 52A (EC 3.6.4.13) Oryza sativa subsp. japonica (Rice) NA GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0016887 15188 FUN_042597 1088 399 478 561 671 NA NA NA NA NA NA NA 15189 FUN_042590 238 68 139 180 62 ptg000039l:78110-81437 P17972 5.21e-47 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 15190 FUN_042590 238 68 139 180 62 ptg000039l:78110-81437 P17972 5.1e-26 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 15191 FUN_042591 10899 6447 3978 8155 3105 ptg000039l:84072-88925 Q87NG3 5.49e-75 Glycine betaine transporter 1 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0022857 15192 FUN_003919 67 9 16 13 3 NA NA NA NA NA NA NA 15193 FUN_003918 23 23 17 17 8 NA NA NA NA NA NA NA 15194 FUN_003917 135 31 63 49 18 NA NA NA NA NA NA NA 15195 FUN_003916 55 88 41 89 123 NA NA NA NA NA NA NA 15196 FUN_003914 0 0 0 25 16 NA NA NA NA NA NA NA 15197 FUN_042598 1715 527 753 1013 599 NA NA NA NA NA NA NA 15198 FUN_003911 159 27 16 106 38 NA NA NA NA NA NA NA 15199 FUN_003910 0 0 14 0 0 NA NA NA NA NA NA NA 15200 FUN_040688 424 254 198 272 310 ptg000031l:11936285-11939328 Q9DBN9 7.15e-55 Probable ATP-dependent RNA helicase DDX59 (EC 3.6.4.13) (DEAD box protein 59) (Zinc finger HIT domain-containing protein 5) Mus musculus (Mouse) NA GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0016887; GO:0046872 15201 FUN_040688 424 254 198 272 310 ptg000031l:11936285-11939328 Q9DBN9 8.74e-25 Probable ATP-dependent RNA helicase DDX59 (EC 3.6.4.13) (DEAD box protein 59) (Zinc finger HIT domain-containing protein 5) Mus musculus (Mouse) NA GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0016887; GO:0046872 15202 FUN_040688 424 254 198 272 310 ptg000031l:11936285-11939328 Q9DBN9 5.78e-22 Probable ATP-dependent RNA helicase DDX59 (EC 3.6.4.13) (DEAD box protein 59) (Zinc finger HIT domain-containing protein 5) Mus musculus (Mouse) NA GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0016887; GO:0046872 15203 FUN_040689 136 50 24 54 37 NA NA NA NA NA NA NA 15204 FUN_040686 20714 21722 9764 16855 12178 NA NA NA NA NA NA NA 15205 FUN_040687 2585 2255 1386 1779 2004 NA NA NA NA NA NA NA 15206 FUN_040684 9294 8692 5191 7903 7405 NA NA NA NA NA NA NA 15207 FUN_040685 542 311 262 465 508 NA NA NA NA NA NA NA 15208 FUN_040682 1728 1072 1332 2046 1987 NA NA NA NA NA NA NA 15209 FUN_040683 299 97 231 266 250 NA NA NA NA NA NA NA 15210 FUN_040680 960 569 859 1285 1032 ptg000031l:11806719-11840102 P27671 4.46e-29 Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1) (CDC25Mm) (Guanine nucleotide-releasing protein) (GNRP) (Ras-specific nucleotide exchange factor CDC25) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; neuron projection development [GO:0031175]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of GTPase activity [GO:0043547]; positive regulation of Ras protein signal transduction [GO:0046579]; Ras protein signal transduction [GO:0007265]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of NMDA receptor activity [GO:2000310]; regulation of Rac protein signal transduction [GO:0035020]; regulation of Ras protein signal transduction [GO:0046578]; regulation of synaptic plasticity [GO:0048167]; response to endoplasmic reticulum stress [GO:0034976]; type B pancreatic cell proliferation [GO:0044342] GO:0005085; GO:0005737; GO:0005829; GO:0005886; GO:0007265; GO:0008022; GO:0016323; GO:0016327; GO:0019901; GO:0030426; GO:0030971; GO:0031175; GO:0031267; GO:0034976; GO:0035020; GO:0035254; GO:0043025; GO:0043547; GO:0044342; GO:0046578; GO:0046579; GO:0048146; GO:0048167; GO:0048168; GO:0090630; GO:0097440; GO:2000310 15211 FUN_012919 3 0 13 0 0 NA NA NA NA NA NA NA 15212 FUN_012915 0 4 17 0 0 NA NA NA NA NA NA NA 15213 FUN_012914 2 15 4 3 0 NA NA NA NA NA NA NA 15214 FUN_012911 56 0 16 32 35 NA NA NA NA NA NA NA 15215 FUN_012910 0 18 0 3 10 NA NA NA NA NA NA NA 15216 FUN_012913 499 126 344 1014 0 NA NA NA NA NA NA NA 15217 FUN_012912 0 0 9 0 0 NA NA NA NA NA NA NA 15218 FUN_043885 51 91 92 103 271 NA NA NA NA NA NA NA 15219 FUN_043884 48 127 92 107 284 NA NA NA NA NA NA NA 15220 FUN_043887 8 0 18 3 119 NA NA NA NA NA NA NA 15221 FUN_043886 2 3 5 1 36 NA NA NA NA NA NA NA 15222 FUN_043881 30 78 55 46 146 NA NA NA NA NA NA NA 15223 FUN_043880 33 70 71 97 233 NA NA NA NA NA NA NA 15224 FUN_043883 7 2 18 2 120 NA NA NA NA NA NA NA 15225 FUN_043882 9 6 20 3 151 NA NA NA NA NA NA NA 15226 FUN_043889 57 217 81 174 464 NA NA NA NA NA NA NA 15227 FUN_043888 8 24 16 24 62 NA NA NA NA NA NA NA 15228 FUN_011259 782 1399 445 1175 965 NA NA NA NA NA NA NA 15229 FUN_011258 2344 2738 1119 3503 2580 NA NA NA NA NA NA NA 15230 FUN_011256 13947 21804 7503 16999 11521 NA NA NA NA NA NA NA 15231 FUN_011255 168 402 152 499 391 NA NA NA NA NA NA NA 15232 FUN_011254 0 5 9 59 8 NA NA NA NA NA NA NA 15233 FUN_011253 4 100 37 411 267 NA NA NA NA NA NA NA 15234 FUN_011252 20 392 37 423 388 NA NA NA NA NA NA NA 15235 FUN_011251 0 0 25 0 124 NA NA NA NA NA NA NA 15236 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 4.94e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15237 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 4.14e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15238 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 1.75e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15239 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 1.97e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15240 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 2.7e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15241 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 2.88e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15242 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 1.37e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15243 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 3.7e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15244 FUN_000336 234 158 129 341 123 ntLink_6:1693813-1696428 Q96AY4 3.72e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15245 FUN_000337 937 713 522 1453 325 NA NA NA NA NA NA NA 15246 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 8.11e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15247 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 1.51e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15248 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 2.41e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15249 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 1.18e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15250 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 8.07e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15251 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 2.78e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15252 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 3.49e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15253 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 1.79e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15254 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 1.53e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15255 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 1.09e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15256 FUN_000334 1777 2079 1524 2722 2872 ntLink_6:1662954-1669239 Q96AY4 2.07e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15257 FUN_000335 1135 577 424 789 929 ntLink_6:1677469-1683274 Q80XJ3 2.68e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15258 FUN_000335 1135 577 424 789 929 ntLink_6:1677469-1683274 Q80XJ3 2.48e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15259 FUN_000335 1135 577 424 789 929 ntLink_6:1677469-1683274 Q80XJ3 2.17e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15260 FUN_000335 1135 577 424 789 929 ntLink_6:1677469-1683274 Q80XJ3 8.92e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15261 FUN_041766 116 88 36 81 49 NA NA NA NA NA NA NA 15262 FUN_041767 4438 2013 1972 4516 3459 NA NA NA NA NA NA NA 15263 FUN_000330 15899 7780 9809 15838 8969 ntLink_6:1595482-1639314 Q71LX4 1.33e-23 Talin-2 Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001726; GO:0005178; GO:0005200; GO:0005737; GO:0005856; GO:0005886; GO:0005916; GO:0005925; GO:0045202; GO:0051015; GO:0098609 15264 FUN_000330 15899 7780 9809 15838 8969 ntLink_6:1595482-1639314 Q71LX4 1.33e-23 Talin-2 Mus musculus (Mouse) cell-cell adhesion [GO:0098609] GO:0001726; GO:0005178; GO:0005200; GO:0005737; GO:0005856; GO:0005886; GO:0005916; GO:0005925; GO:0045202; GO:0051015; GO:0098609 15265 FUN_029471 11 5 0 23 20 NA NA NA NA NA NA NA 15266 FUN_041768 5143 3953 2855 5377 4336 NA NA NA NA NA NA NA 15267 FUN_041769 2587 1865 815 774 480 NA NA NA NA NA NA NA 15268 FUN_042659 156 73 191 124 248 NA NA NA NA NA NA NA 15269 FUN_012773 101 94 83 144 62 NA NA NA NA NA NA NA 15270 FUN_000338 212 128 76 111 236 NA NA NA NA NA NA NA 15271 FUN_000339 148 12 75 35 73 ntLink_6:1715233-1717327 Q80XJ3 1.79e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15272 FUN_000339 148 12 75 35 73 ntLink_6:1715233-1717327 Q80XJ3 2.8e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15273 FUN_000339 148 12 75 35 73 ntLink_6:1715233-1717327 Q80XJ3 4.04e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15274 FUN_000339 148 12 75 35 73 ntLink_6:1715233-1717327 Q80XJ3 8.05e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15275 FUN_000339 148 12 75 35 73 ntLink_6:1715233-1717327 Q80XJ3 3.93e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15276 FUN_000339 148 12 75 35 73 ntLink_6:1715233-1717327 Q80XJ3 7.18e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 15277 FUN_012772 25201 31744 15746 21285 19183 ptg000008l:12630232-12636384 Q8JGR4 1.92e-34 60S ribosomal protein L24 Danio rerio (Zebrafish) (Brachydanio rerio) chordate embryonic development [GO:0043009]; cytoplasmic translation [GO:0002181] GO:0002181; GO:0003729; GO:0003735; GO:0022625; GO:0043009 15278 FUN_017265 0 0 0 13 0 NA NA NA NA NA NA NA 15279 FUN_012775 9 1 3 0 6 NA NA NA NA NA NA NA 15280 FUN_029475 1766 1205 504 1064 890 NA NA NA NA NA NA NA 15281 FUN_012777 4920 4728 2707 3216 2936 ptg000008l:12698576-12701655 A7RL75 1.34e-31 Tetratricopeptide repeat protein 36 homolog (TPR repeat protein 36 homolog) Nematostella vectensis (Starlet sea anemone) cilium assembly [GO:0060271] GO:0060271 15282 FUN_012777 4920 4728 2707 3216 2936 ptg000008l:12698576-12701655 A7RL75 2.29e-24 Tetratricopeptide repeat protein 36 homolog (TPR repeat protein 36 homolog) Nematostella vectensis (Starlet sea anemone) cilium assembly [GO:0060271] GO:0060271 15283 FUN_029477 1236 973 551 1448 1158 ptg000023l:2339472-2345963 P53702 6.32e-25 Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) Mus musculus (Mouse) cytochrome c-heme linkage [GO:0018063] GO:0004408; GO:0005739; GO:0005743; GO:0005829; GO:0016020; GO:0018063; GO:0020037; GO:0046872 15284 FUN_008655 12 0 0 0 0 NA NA NA NA NA NA NA 15285 FUN_008657 41 9 19 23 19 ptg000002l:14073020-14098488 Q94K49 1.18e-23 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 15286 FUN_008656 0 0 81 0 0 NA NA NA NA NA NA NA 15287 FUN_008651 317 230 174 269 149 NA NA NA NA NA NA NA 15288 FUN_008650 424 325 209 561 241 NA NA NA NA NA NA NA 15289 FUN_008653 403 495 153 367 246 ptg000002l:14053116-14054813 Q1JQ66 2.66e-24 Solute carrier family 35 member E3 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005338; GO:0005794; GO:0015297; GO:0016020 15290 FUN_008652 6467 7939 3518 6030 4432 NA NA NA NA NA NA NA 15291 FUN_017263 23 73 0 38 74 NA NA NA NA NA NA NA 15292 FUN_008659 814 549 543 446 376 NA NA NA NA NA NA NA 15293 FUN_008658 70 24 7 58 36 NA NA NA NA NA NA NA 15294 FUN_029007 299 128 228 607 696 NA NA NA NA NA NA NA 15295 FUN_029006 85 110 97 174 181 NA NA NA NA NA NA NA 15296 FUN_029001 30 43 8 69 39 NA NA NA NA NA NA NA 15297 FUN_029000 110 63 89 179 141 NA NA NA NA NA NA NA 15298 FUN_029003 2 0 8 0 0 ptg000022l:7038400-7043625 C5NSL2 4.18e-25 DELTA-actitoxin-Aas1a (DELTA-AITX-Aas1a) (Bandaporin) (Cytolysin bp-1) Anthopleura asiatica (Sea anemone) cation transport [GO:0006812]; cytolysis in another organism [GO:0051715]; pore complex assembly [GO:0046931] GO:0005576; GO:0006812; GO:0015267; GO:0042151; GO:0044218; GO:0046930; GO:0046931; GO:0051715; GO:0090729 15299 FUN_029002 0 0 0 0 6 NA NA NA NA NA NA NA 15300 FUN_033072 0 2 2 212 0 NA NA NA NA NA NA NA 15301 FUN_033070 0 0 5 101 15 NA NA NA NA NA NA NA 15302 FUN_033076 8 0 16 7 11 NA NA NA NA NA NA NA 15303 FUN_033075 7 0 0 0 0 NA NA NA NA NA NA NA 15304 FUN_033074 0 0 0 0 25 NA NA NA NA NA NA NA 15305 FUN_033079 0 7 0 0 0 NA NA NA NA NA NA NA 15306 FUN_033078 5 0 0 0 12 NA NA NA NA NA NA NA 15307 FUN_042868 13 0 0 17 13 NA NA NA NA NA NA NA 15308 FUN_042869 60 30 9 54 12 NA NA NA NA NA NA NA 15309 FUN_042864 2 586 2 10 266 NA NA NA NA NA NA NA 15310 FUN_016705 479 134 358 412 237 NA NA NA NA NA NA NA 15311 FUN_016706 14825 10277 9275 13553 13467 NA NA NA NA NA NA NA 15312 FUN_016707 1503 1540 1431 1054 1948 NA NA NA NA NA NA NA 15313 FUN_042860 17 61 0 36 62 NA NA NA NA NA NA NA 15314 FUN_016701 451 271 118 166 195 NA NA NA NA NA NA NA 15315 FUN_016703 41 29 16 51 65 NA NA NA NA NA NA NA 15316 FUN_012285 304 385 235 248 118 ptg000008l:7324614-7358308 P04323 1.3e-50 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 15317 FUN_012285 304 385 235 248 118 ptg000008l:7324614-7358308 P04323 1.3e-50 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 15318 FUN_012284 287 91 129 182 147 ptg000008l:7306790-7308482 P35406 1.05e-27 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 15319 FUN_012287 2512 1161 1626 2556 2477 NA NA NA NA NA NA NA 15320 FUN_012286 0 19 0 9 12 NA NA NA NA NA NA NA 15321 FUN_012281 693 457 369 402 1003 ptg000008l:7270769-7284680 E7F5E1 5.06e-28 Centrosomal protein of 162 kDa (Cep162) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; heart looping [GO:0001947] GO:0001947; GO:0005813; GO:0005814; GO:0005879; GO:0060271 15322 FUN_012280 2070 1405 1273 1260 1386 NA NA NA NA NA NA NA 15323 FUN_012283 2966 3301 2071 2532 2398 NA NA NA NA NA NA NA 15324 FUN_012282 2946 2230 1880 2830 2199 NA NA NA NA NA NA NA 15325 FUN_038493 23 237 96 57 57 ptg000027l:7960029-7961005 Q8K2J9 1.01e-46 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 15326 FUN_038493 23 237 96 57 57 ptg000027l:7960029-7961005 Q8K2J9 1.01e-46 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 15327 FUN_012289 69 0 16 9 0 NA NA NA NA NA NA NA 15328 FUN_012288 111 19 27 33 8 NA NA NA NA NA NA NA 15329 FUN_028358 0 0 0 54 0 NA NA NA NA NA NA NA 15330 FUN_028359 0 0 0 160 0 NA NA NA NA NA NA NA 15331 FUN_028352 0 203 355 77 448 NA NA NA NA NA NA NA 15332 FUN_028353 0 0 11 0 0 NA NA NA NA NA NA NA 15333 FUN_028350 1204 152 316 482 545 NA NA NA NA NA NA NA 15334 FUN_028351 910 878 694 1895 893 NA NA NA NA NA NA NA 15335 FUN_028356 0 0 0 75 0 NA NA NA NA NA NA NA 15336 FUN_028357 0 0 0 846 0 NA NA NA NA NA NA NA 15337 FUN_028354 1970 2714 1757 2758 1736 ptg000021l:18695057-18802949 P14381 1.89e-43 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 15338 FUN_028355 0 0 0 342 0 NA NA NA NA NA NA NA 15339 FUN_010665 2494 1755 1731 1974 900 NA NA NA NA NA NA NA 15340 FUN_010664 7846 6040 3221 7219 6052 ptg000007l:1335315-1347675 O46629 7.21e-37 Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.155) (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)] Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0003988; GO:0005739; GO:0005741; GO:0005743; GO:0005783; GO:0006635; GO:0050633 15341 FUN_010664 7846 6040 3221 7219 6052 ptg000007l:1335315-1347675 O46629 7.21e-37 Trifunctional enzyme subunit beta, mitochondrial (TP-beta) [Includes: 3-ketoacyl-CoA thiolase (EC 2.3.1.155) (EC 2.3.1.16) (Acetyl-CoA acyltransferase) (Beta-ketothiolase)] Bos taurus (Bovine) fatty acid beta-oxidation [GO:0006635] GO:0003988; GO:0005739; GO:0005741; GO:0005743; GO:0005783; GO:0006635; GO:0050633 15342 FUN_010667 17799 17236 14340 10577 8651 NA NA NA NA NA NA NA 15343 FUN_010666 0 0 0 0 9 NA NA NA NA NA NA NA 15344 FUN_010661 8260 5283 3776 7033 5370 NA NA NA NA NA NA NA 15345 FUN_010660 1971 1028 632 1360 1370 NA NA NA NA NA NA NA 15346 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 5.4e-44 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15347 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 9.26e-37 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15348 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 1.73e-36 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15349 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 1.65e-34 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15350 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 8.19e-32 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15351 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 2.42e-30 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15352 FUN_010663 2849 2709 1780 3086 2753 ptg000007l:1308922-1335047 Q99MV1 2.79e-29 Tudor domain-containing protein 1 Mus musculus (Mouse) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0005829; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0045202; GO:0046872; GO:0051321; GO:0071546; GO:1990904 15353 FUN_010662 1111 701 713 814 443 ptg000007l:1301616-1305355 Q8IV20 2.94e-23 Purine nucleoside phosphorylase LACC1 (EC 2.4.2.1) (Adenosine deaminase LACC1) (EC 3.5.4.4) (Fatty acid metabolism-immunity nexus) (Guanosine phosphorylase LACC1) (Laccase domain-containing protein 1) (S-methyl-5'-thioadenosine phosphorylase LACC1) (EC 2.4.2.28) Homo sapiens (Human) inflammatory response [GO:0006954]; innate immune response [GO:0045087]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cytokine production involved in immune response [GO:0002720]; regulation of cellular pH [GO:0030641]; regulation of inflammatory response [GO:0050727]; regulation of purine nucleotide metabolic process [GO:1900542] GO:0002221; GO:0002720; GO:0004000; GO:0004731; GO:0005507; GO:0005634; GO:0005777; GO:0005783; GO:0006954; GO:0017061; GO:0030641; GO:0045087; GO:0046936; GO:0047975; GO:0050727; GO:0070431; GO:1900542 15354 FUN_010669 366 483 331 425 329 NA NA NA NA NA NA NA 15355 FUN_010668 224 142 76 160 339 NA NA NA NA NA NA NA 15356 FUN_012139 2084 1240 1077 2339 1805 NA NA NA NA NA NA NA 15357 FUN_012138 1960 1601 827 1414 1578 NA NA NA NA NA NA NA 15358 FUN_012137 2467 1197 1490 1311 1990 NA NA NA NA NA NA NA 15359 FUN_012136 23572 22159 15355 23855 16905 NA NA NA NA NA NA NA 15360 FUN_012135 2192 1293 652 3203 2568 NA NA NA NA NA NA NA 15361 FUN_012134 1989 1860 1816 1743 1459 NA NA NA NA NA NA NA 15362 FUN_012133 0 0 0 10 10 NA NA NA NA NA NA NA 15363 FUN_012132 2663 752 1606 1908 2312 ptg000008l:5488610-5529269 Q07113 6.4e-37 Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222) Mus musculus (Mouse) animal organ regeneration [GO:0031100]; G protein-coupled receptor signaling pathway [GO:0007186]; liver development [GO:0001889]; lysosomal transport [GO:0007041]; positive regulation by host of viral process [GO:0044794]; positive regulation of apoptotic process [GO:0043065]; post-embryonic development [GO:0009791]; regulation of apoptotic process [GO:0042981]; response to retinoic acid [GO:0032526]; response to tetrachloromethane [GO:1904772]; spermatogenesis [GO:0007283] GO:0000139; GO:0001889; GO:0001965; GO:0001972; GO:0005520; GO:0005537; GO:0005615; GO:0005634; GO:0005641; GO:0005768; GO:0005769; GO:0005770; GO:0005794; GO:0005802; GO:0005886; GO:0007041; GO:0007186; GO:0007283; GO:0009791; GO:0009986; GO:0010008; GO:0016020; GO:0019899; GO:0030118; GO:0030139; GO:0030140; GO:0031100; GO:0031995; GO:0032526; GO:0038023; GO:0042802; GO:0042981; GO:0043065; GO:0044794; GO:0048471; GO:0051219; GO:1904772; GO:1905394 15364 FUN_012131 359 71 34 519 121 NA NA NA NA NA NA NA 15365 FUN_012130 825 1129 108 1888 638 NA NA NA NA NA NA NA 15366 FUN_020837 0 0 0 35 26 NA NA NA NA NA NA NA 15367 FUN_020836 93 51 16 115 155 NA NA NA NA NA NA NA 15368 FUN_020835 1395 1006 369 1363 874 NA NA NA NA NA NA NA 15369 FUN_020833 0 0 0 36 54 NA NA NA NA NA NA NA 15370 FUN_020832 0 6 2 5 25 NA NA NA NA NA NA NA 15371 FUN_020831 0 0 0 16 33 NA NA NA NA NA NA NA 15372 FUN_020838 351 80 100 390 648 NA NA NA NA NA NA NA 15373 FUN_038807 1091 1307 738 876 547 ptg000027l:11607372-11608098 P51824 1.57e-89 ADP-ribosylation factor 1 (EC 3.6.5.2) Solanum tuberosum (Potato) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0006886; GO:0016192 15374 FUN_038806 290 335 164 254 174 ptg000027l:11602564-11607062 P28606 9.97e-21 Uncharacterized protein SYNPCC7002_A1628 Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) histone deacetylation [GO:0016575] GO:0004407; GO:0016575 15375 FUN_038805 1559 799 722 1395 1161 ptg000027l:11581037-11599732 Q6GMF8 2.23e-29 Inactive rhomboid protein 1 (iRhom1) (Rhomboid family member 1) Danio rerio (Zebrafish) (Brachydanio rerio) cell migration [GO:0016477]; cell population proliferation [GO:0008283]; negative regulation of protein secretion [GO:0050709]; protein transport [GO:0015031]; regulation of epidermal growth factor receptor signaling pathway [GO:0042058]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein secretion [GO:0050708] GO:0000139; GO:0005789; GO:0008283; GO:0015031; GO:0016477; GO:0019838; GO:0042058; GO:0050708; GO:0050709; GO:0061136 15376 FUN_038804 76080 101937 35214 60015 49741 ptg000027l:11573858-11578044 Q90YS3 2.65e-53 40S ribosomal protein S2 Ictalurus punctatus (Channel catfish) (Silurus punctatus) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015935 15377 FUN_038804 76080 101937 35214 60015 49741 ptg000027l:11573858-11578044 Q90YS3 8.84e-22 40S ribosomal protein S2 Ictalurus punctatus (Channel catfish) (Silurus punctatus) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015935 15378 FUN_038803 1449 675 711 888 864 ptg000027l:11554856-11572499 Q9H9P5 4.02e-58 Putative E3 ubiquitin-protein ligase UNKL (EC 2.3.2.-) (RING finger protein unkempt-like) (Zinc finger CCCH domain-containing protein 5-like) Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0005634; GO:0005829; GO:0016567; GO:0016740; GO:0046872 15379 FUN_038802 381 269 251 272 311 NA NA NA NA NA NA NA 15380 FUN_038801 505 241 169 140 296 ptg000027l:11540145-11541494 Q9SKT4 8.9e-21 Formiminotransferase cyclodeaminase-like protein (AtFTCD-L) (EC 2.1.2.5) Arabidopsis thaliana (Mouse-ear cress) root development [GO:0048364]; secretion [GO:0046903] GO:0005542; GO:0016740; GO:0046903; GO:0048364 15381 FUN_038800 94 128 105 105 149 ptg000027l:11536859-11539612 Q22875 1.23e-41 Leucine-rich repeat protein soc-2 (Suppressor of Clr protein 2) (Suppressor of activated let-60 Ras protein 8) Caenorhabditis elegans fibroblast growth factor receptor signaling pathway [GO:0008543]; muscle organ development [GO:0007517]; positive regulation of Ras protein signal transduction [GO:0046579]; regulation of cell projection organization [GO:0031344]; signal transduction [GO:0007165]; vulval development [GO:0040025] GO:0007165; GO:0007517; GO:0008543; GO:0031267; GO:0031344; GO:0040025; GO:0046579 15382 FUN_038809 1124 410 583 836 1201 NA NA NA NA NA NA NA 15383 FUN_038808 885 628 415 726 752 NA NA NA NA NA NA NA 15384 FUN_017917 47 24 0 0 0 ptg000012l:1860488-1861480 Q9DAJ5 1.9e-25 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0007018; GO:0045505 15385 FUN_018726 0 0 0 11 0 NA NA NA NA NA NA NA 15386 FUN_017915 6601 5274 4653 7702 5901 ptg000012l:1827935-1853042 Q7SIA2 3.14e-38 Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase) (ProRS)] Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) cellular response to insulin stimulus [GO:0032869]; cellular response to type II interferon [GO:0071346]; glutamyl-tRNA aminoacylation [GO:0006424]; negative regulation of translation [GO:0017148]; prolyl-tRNA aminoacylation [GO:0006433]; regulation of long-chain fatty acid import into cell [GO:0140212] GO:0004818; GO:0004827; GO:0005524; GO:0005829; GO:0005886; GO:0006424; GO:0006433; GO:0008270; GO:0017101; GO:0017148; GO:0032869; GO:0035613; GO:0042803; GO:0051020; GO:0071346; GO:0097452; GO:0140212; GO:1990904 15387 FUN_043052 31 20 17 54 27 ptg000047l:3465050-3471758 Q96AY4 6.76e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15388 FUN_043052 31 20 17 54 27 ptg000047l:3465050-3471758 Q96AY4 1.79e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15389 FUN_043052 31 20 17 54 27 ptg000047l:3465050-3471758 Q96AY4 4.24e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15390 FUN_043052 31 20 17 54 27 ptg000047l:3465050-3471758 Q96AY4 8.44e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15391 FUN_043052 31 20 17 54 27 ptg000047l:3465050-3471758 Q96AY4 5.89e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15392 FUN_043052 31 20 17 54 27 ptg000047l:3465050-3471758 Q96AY4 2.77e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15393 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 4.45e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15394 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 1.2e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15395 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 2.6e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15396 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 7.42e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15397 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 9.35e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15398 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 5.74e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15399 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 1.54e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15400 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 2.25e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15401 FUN_043053 36 25 7 44 20 ptg000047l:3485571-3496051 Q96AY4 4.78e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15402 FUN_011530 32 0 130 8 426 NA NA NA NA NA NA NA 15403 FUN_043051 40 41 11 91 52 ptg000047l:3433772-3440441 Q96AY4 5.34e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15404 FUN_043051 40 41 11 91 52 ptg000047l:3433772-3440441 Q96AY4 9.97e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15405 FUN_043051 40 41 11 91 52 ptg000047l:3433772-3440441 Q96AY4 2.59e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15406 FUN_043051 40 41 11 91 52 ptg000047l:3433772-3440441 Q96AY4 5.81e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15407 FUN_043051 40 41 11 91 52 ptg000047l:3433772-3440441 Q96AY4 3.54e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15408 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 4.16e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15409 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 1.25e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15410 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 1.68e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15411 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 4.96e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15412 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 1.28e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15413 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 2.21e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15414 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 3.1e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15415 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 6.74e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15416 FUN_043056 58 39 16 57 44 ptg000047l:3540326-3548584 Q96AY4 5.94e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15417 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 3.92e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15418 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 3.92e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15419 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.61e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15420 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.61e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15421 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.89e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15422 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.89e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15423 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.31e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15424 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 2.67e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15425 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 2.01e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15426 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.92e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15427 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 8.36e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15428 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.03e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15429 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.54e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15430 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 1.63e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15431 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 6.66e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15432 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 8.7e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15433 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 2.35e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15434 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 2.62e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15435 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 2.76e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15436 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 3.47e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15437 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 6.39e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15438 FUN_043055 23 0 13 50 36 ptg000047l:3520831-3523112 Q96AY4 9.61e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15439 FUN_018722 54 16 29 57 3 NA NA NA NA NA NA NA 15440 FUN_017911 132 255 79 391 560 NA NA NA NA NA NA NA 15441 FUN_013668 36 8 0 42 4 NA NA NA NA NA NA NA 15442 FUN_013667 12 0 0 0 0 NA NA NA NA NA NA NA 15443 FUN_013660 1292 597 123 1090 674 NA NA NA NA NA NA NA 15444 FUN_013661 591 531 378 430 301 NA NA NA NA NA NA NA 15445 FUN_013662 44 54 19 39 80 NA NA NA NA NA NA NA 15446 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 1.01e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15447 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 1.51e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15448 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 1.58e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15449 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 5.17e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15450 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 1.29e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15451 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 4.87e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15452 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 9.07e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15453 FUN_009685 0 0 7 9 39 ptg000004l:10353904-10362263 Q96AY4 1.02e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15454 FUN_009681 36 29 47 0 72 NA NA NA NA NA NA NA 15455 FUN_009680 54 80 35 38 85 NA NA NA NA NA NA NA 15456 FUN_009683 0 36 0 0 73 NA NA NA NA NA NA NA 15457 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 3.83e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15458 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 1.75e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15459 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 1.87e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15460 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 2.5e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15461 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 4.19e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15462 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 4.01e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15463 FUN_009682 215 954 0 476 110 ptg000004l:10305249-10314656 Q96AY4 5.77e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15464 FUN_009688 54 314 127 148 12 NA NA NA NA NA NA NA 15465 FUN_026295 205 0 112 29 13 NA NA NA NA NA NA NA 15466 FUN_026294 367 83 209 137 122 ptg000020l:7417240-7461937 P16157 6.35e-68 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15467 FUN_026294 367 83 209 137 122 ptg000020l:7417240-7461937 P16157 7.12e-60 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15468 FUN_026294 367 83 209 137 122 ptg000020l:7417240-7461937 P16157 9.81e-60 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15469 FUN_026294 367 83 209 137 122 ptg000020l:7417240-7461937 P16157 5.56e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15470 FUN_026294 367 83 209 137 122 ptg000020l:7417240-7461937 P16157 7.29e-45 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15471 FUN_026297 1001 550 614 1084 948 NA NA NA NA NA NA NA 15472 FUN_026296 224 110 254 185 102 ptg000020l:7486562-7498662 P16157 3.25e-75 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15473 FUN_026296 224 110 254 185 102 ptg000020l:7486562-7498662 P16157 7.69e-66 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15474 FUN_026296 224 110 254 185 102 ptg000020l:7486562-7498662 P16157 2e-48 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15475 FUN_026296 224 110 254 185 102 ptg000020l:7486562-7498662 P16157 1.55e-45 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 15476 FUN_026291 16 0 0 142 49 NA NA NA NA NA NA NA 15477 FUN_026290 519 9 22 23 15 ptg000020l:7386839-7393491 Q4UMH6 7.08e-43 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15478 FUN_026290 519 9 22 23 15 ptg000020l:7386839-7393491 Q4UMH6 1.95e-40 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15479 FUN_026290 519 9 22 23 15 ptg000020l:7386839-7393491 Q4UMH6 7.4e-39 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15480 FUN_026290 519 9 22 23 15 ptg000020l:7386839-7393491 Q4UMH6 2.15e-38 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15481 FUN_026290 519 9 22 23 15 ptg000020l:7386839-7393491 Q4UMH6 1.83e-32 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 15482 FUN_026299 657 247 119 177 258 NA NA NA NA NA NA NA 15483 FUN_026298 1599 1299 1164 1595 961 NA NA NA NA NA NA NA 15484 FUN_009539 0 8 0 0 12 NA NA NA NA NA NA NA 15485 FUN_025929 2068 2914 926 5038 1828 ptg000020l:2130307-2135865 Q6NUT3 3.14e-33 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 15486 FUN_025926 198 134 188 92 48 NA NA NA NA NA NA NA 15487 FUN_025927 670 184 382 593 245 NA NA NA NA NA NA NA 15488 FUN_009535 432 91 73 516 247 NA NA NA NA NA NA NA 15489 FUN_025925 24709 42370 23531 21257 19689 ptg000020l:2074353-2077394 Q4R3D4 2.87e-29 Elongation factor 1-delta (EF-1-delta) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0003677; GO:0003746; GO:0005634; GO:0005853 15490 FUN_025922 23 270 82 115 129 NA NA NA NA NA NA NA 15491 FUN_009532 27766 21290 17694 32046 28243 ptg000004l:8124143-8148796 D3ZQD3 1.99e-31 2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like) Rattus norvegicus (Rat) 2-oxoglutarate metabolic process [GO:0006103]; glycolytic process [GO:0006096]; tricarboxylic acid cycle [GO:0006099] GO:0004591; GO:0005739; GO:0005759; GO:0006096; GO:0006099; GO:0006103; GO:0030976; GO:0045252; GO:0046872 15492 FUN_025920 449 983 13 779 269 NA NA NA NA NA NA NA 15493 FUN_025921 3120 5867 1268 2480 2327 NA NA NA NA NA NA NA 15494 FUN_023518 44 7 1 10 50 NA NA NA NA NA NA NA 15495 FUN_026747 9 0 0 7 0 NA NA NA NA NA NA NA 15496 FUN_026746 17 0 11 97 38 NA NA NA NA NA NA NA 15497 FUN_026745 82 0 101 58 86 NA NA NA NA NA NA NA 15498 FUN_023515 1413 1064 269 1826 1299 NA NA NA NA NA NA NA 15499 FUN_023517 297 1603 262 522 129 NA NA NA NA NA NA NA 15500 FUN_026740 5 0 7 10 92 NA NA NA NA NA NA NA 15501 FUN_015542 3 0 7 0 17 NA NA NA NA NA NA NA 15502 FUN_015541 400 135 142 275 318 NA NA NA NA NA NA NA 15503 FUN_025308 1912 1001 699 1435 713 NA NA NA NA NA NA NA 15504 FUN_025309 19915 24536 15280 13010 5755 NA NA NA NA NA NA NA 15505 FUN_040248 352 177 178 341 415 NA NA NA NA NA NA NA 15506 FUN_040245 17 23 0 1 2 NA NA NA NA NA NA NA 15507 FUN_018676 2 0 2 14 12 NA NA NA NA NA NA NA 15508 FUN_018674 32 1 25 14 12 NA NA NA NA NA NA NA 15509 FUN_018671 11 89 25 24 43 NA NA NA NA NA NA NA 15510 FUN_010213 0 0 0 6 0 NA NA NA NA NA NA NA 15511 FUN_016391 136 155 294 226 127 NA NA NA NA NA NA NA 15512 FUN_025218 353 0 0 120 16 NA NA NA NA NA NA NA 15513 FUN_025219 521 193 56 175 255 NA NA NA NA NA NA NA 15514 FUN_025214 601 533 387 450 316 NA NA NA NA NA NA NA 15515 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 1.14e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15516 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 6.81e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15517 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 6.4e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15518 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 2.38e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15519 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 9.11e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15520 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 1.37e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15521 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 7.73e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15522 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 1.39e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15523 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 9e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15524 FUN_025216 329 245 29 144 268 ptg000019l:32523-37937 Q96AY4 9.38e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15525 FUN_025217 450 0 45 153 0 NA NA NA NA NA NA NA 15526 FUN_025211 0 0 0 0 9 NA NA NA NA NA NA NA 15527 FUN_025212 0 0 15 0 0 NA NA NA NA NA NA NA 15528 FUN_025213 1075 536 111 930 594 NA NA NA NA NA NA NA 15529 FUN_018175 0 0 0 45 0 NA NA NA NA NA NA NA 15530 FUN_027913 13 20 0 12 26 NA NA NA NA NA NA NA 15531 FUN_027912 93 0 85 29 0 NA NA NA NA NA NA NA 15532 FUN_018171 15 1 0 0 0 NA NA NA NA NA NA NA 15533 FUN_018170 164 95 153 102 74 NA NA NA NA NA NA NA 15534 FUN_014398 0 0 0 28 25 NA NA NA NA NA NA NA 15535 FUN_018173 34 0 0 35 40 NA NA NA NA NA NA NA 15536 FUN_000141 15 4 28 4 78 ntLink_4:214123-215334 P35067 9.96e-81 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15537 FUN_014390 0 0 9 0 0 NA NA NA NA NA NA NA 15538 FUN_014393 88 0 63 0 90 NA NA NA NA NA NA NA 15539 FUN_014395 19 5 8 7 12 NA NA NA NA NA NA NA 15540 FUN_014394 0 35 5 10 24 NA NA NA NA NA NA NA 15541 FUN_014397 0 0 21 0 8 NA NA NA NA NA NA NA 15542 FUN_014396 56 9 6 16 20 NA NA NA NA NA NA NA 15543 FUN_040607 0 0 19 0 80 NA NA NA NA NA NA NA 15544 FUN_035220 5537 5687 3557 6163 3330 ptg000025l:5259515-5283244 Q9NGQ2 1.85e-30 Kinesin-related protein 1 (Kinesin family member 1) (Kinesin-3) Dictyostelium discoideum (Social amoeba) cytoskeleton-dependent intracellular transport [GO:0030705]; microtubule-based movement [GO:0007018]; plus-end-directed organelle transport along microtubule [GO:0072386]; plus-end-directed vesicle transport along microtubule [GO:0072383]; vesicle transport along microtubule [GO:0047496] GO:0003777; GO:0005524; GO:0005546; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0008574; GO:0016887; GO:0030659; GO:0030705; GO:0042802; GO:0047496; GO:0072383; GO:0072386 15545 FUN_035221 1520 1142 521 774 835 ptg000025l:5288512-5294883 Q6DE14 2.63e-24 Transcription factor E2F4 (E2F-4) Xenopus laevis (African clawed frog) centriole assembly [GO:0098534]; motile cilium assembly [GO:0044458]; multi-ciliated epithelial cell differentiation [GO:1903251]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000978; GO:0003700; GO:0005634; GO:0005667; GO:0044458; GO:0045944; GO:0046983; GO:0098534; GO:1903251 15546 FUN_000143 2 0 4 1 12 ntLink_4:220377-221140 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15547 FUN_035226 878 594 453 1082 504 ptg000025l:5344474-5348418 Q5PR73 3.17e-25 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Mus musculus (Mouse) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 15548 FUN_035226 878 594 453 1082 504 ptg000025l:5344474-5348418 Q5PR73 1.6e-22 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Mus musculus (Mouse) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 15549 FUN_035228 203 239 170 250 346 NA NA NA NA NA NA NA 15550 FUN_035229 920 750 406 835 722 NA NA NA NA NA NA NA 15551 FUN_036750 1938 1301 814 1290 1069 NA NA NA NA NA NA NA 15552 FUN_036753 3058 1453 1294 2272 2603 ptg000026l:1502439-1525825 Q2V2M9 4.31e-21 FH1/FH2 domain-containing protein 3 (Formactin-2) (Formin homolog overexpressed in spleen 2) (hFHOS2) Homo sapiens (Human) cardiac myofibril assembly [GO:0055003]; cortical actin cytoskeleton organization [GO:0030866]; negative regulation of actin filament polymerization [GO:0030837]; sarcomere organization [GO:0045214] GO:0005737; GO:0005856; GO:0030018; GO:0030837; GO:0030866; GO:0045214; GO:0051015; GO:0055003 15553 FUN_036752 488 204 163 358 533 NA NA NA NA NA NA NA 15554 FUN_001689 0 0 11 5 0 NA NA NA NA NA NA NA 15555 FUN_036754 172 182 174 90 188 NA NA NA NA NA NA NA 15556 FUN_036757 4438 4318 3935 3102 1770 ptg000026l:1589139-1598172 Q09575 4.5e-26 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15557 FUN_036757 4438 4318 3935 3102 1770 ptg000026l:1589139-1598172 Q09575 4.5e-26 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15558 FUN_036757 4438 4318 3935 3102 1770 ptg000026l:1589139-1598172 Q09575 4.5e-26 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 15559 FUN_036756 3525 1933 1288 3179 1591 ptg000026l:1581485-1588196 Q08CH8 6.53e-29 Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872; GO:0048471 15560 FUN_036756 3525 1933 1288 3179 1591 ptg000026l:1581485-1588196 Q08CH8 2.02e-27 Zinc finger TRAF-type-containing protein 1 (Cysteine and histidine-rich protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872; GO:0048471 15561 FUN_001685 18 14 0 0 0 ntLink_6:15009388-15011123 P79218 5.91e-40 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 15562 FUN_001684 7 1 7 7 7 NA NA NA NA NA NA NA 15563 FUN_001687 216 130 149 299 302 NA NA NA NA NA NA NA 15564 FUN_001686 0 0 0 0 7 NA NA NA NA NA NA NA 15565 FUN_001681 23 0 5 32 5 ntLink_6:14975841-14977164 Q8IN35 1.95e-37 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 15566 FUN_001680 0 0 0 15 0 NA NA NA NA NA NA NA 15567 FUN_001683 2559 3861 913 2080 1323 ntLink_6:14998860-14999793 Q02974 5.28e-102 Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase) Rattus norvegicus (Rat) carbohydrate catabolic process [GO:0016052]; carbohydrate phosphorylation [GO:0046835]; fructose catabolic process [GO:0006001]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; fructose metabolic process [GO:0006000]; regulation of glycogen metabolic process [GO:0070873]; response to fructose [GO:0009750]; response to glucose [GO:0009749]; response to insulin [GO:0032868]; response to sucrose [GO:0009744]; response to zinc ion [GO:0010043] GO:0004454; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006000; GO:0006001; GO:0009744; GO:0009749; GO:0009750; GO:0010043; GO:0016052; GO:0032868; GO:0046835; GO:0061624; GO:0070873 15568 FUN_001682 155 57 164 211 71 ntLink_6:14978890-14980096 Q8IN35 9.16e-39 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 15569 FUN_039732 0 8 18 0 0 NA NA NA NA NA NA NA 15570 FUN_039733 0 0 0 3 58 NA NA NA NA NA NA NA 15571 FUN_039730 0 43 0 2 0 NA NA NA NA NA NA NA 15572 FUN_039731 0 90 6 0 0 NA NA NA NA NA NA NA 15573 FUN_039739 0 11 41 0 16 NA NA NA NA NA NA NA 15574 FUN_021829 0 0 0 9 0 NA NA NA NA NA NA NA 15575 FUN_021821 18 0 40 13 114 NA NA NA NA NA NA NA 15576 FUN_021820 9 0 7 7 13 NA NA NA NA NA NA NA 15577 FUN_031255 648 597 0 443 3 NA NA NA NA NA NA NA 15578 FUN_031254 0 0 0 0 6 NA NA NA NA NA NA NA 15579 FUN_031257 32 63 9 72 53 NA NA NA NA NA NA NA 15580 FUN_038134 133 235 152 244 235 ptg000027l:2929421-2935371 Q8L7C8 5.46e-25 Protein REDUCED WALL ACETYLATION 1 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; plant-type secondary cell wall biogenesis [GO:0009834]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000139; GO:0005794; GO:0005975; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:1990937 15581 FUN_031251 440 269 286 518 446 ptg000023l:18550580-18558388 Q5ZMT7 6.17e-37 AarF domain-containing protein kinase 1 (EC 2.7.-.-) Gallus gallus (Chicken) lipid homeostasis [GO:0055088]; mitochondrion organization [GO:0007005]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005576; GO:0005743; GO:0006468; GO:0007005; GO:0031966; GO:0055088 15582 FUN_031253 9 12 0 4 0 NA NA NA NA NA NA NA 15583 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 5.64e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15584 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 1.49e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15585 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 5.59e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15586 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 6.96e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15587 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 1e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15588 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 1.5e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15589 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 5.4e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15590 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 7.07e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15591 FUN_028700 0 21 0 9 0 ptg000022l:2852910-2862283 Q96AY4 4.85e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15592 FUN_031259 330 54 45 116 14 NA NA NA NA NA NA NA 15593 FUN_023135 82 60 0 18 41 NA NA NA NA NA NA NA 15594 FUN_028702 0 0 0 6 0 ptg000022l:2895806-2900303 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15595 FUN_028702 0 0 0 6 0 ptg000022l:2895806-2900303 Q96AY4 1.09e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15596 FUN_028702 0 0 0 6 0 ptg000022l:2895806-2900303 Q96AY4 8.64e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15597 FUN_028702 0 0 0 6 0 ptg000022l:2895806-2900303 Q96AY4 1.44e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15598 FUN_028702 0 0 0 6 0 ptg000022l:2895806-2900303 Q96AY4 2.53e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15599 FUN_023133 1462 653 519 717 394 ptg000017l:4024905-4028394 Q9EPZ8 1.54e-93 E3 ubiquitin-protein ligase RNF103 (EC 2.3.2.27) (Protein ADRG34) (RING finger protein 103) (RING-type E3 ubiquitin transferase RNF103) (Zinc finger protein 103) (Zfp-103) Rattus norvegicus (Rat) protein ubiquitination [GO:0016567]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004842; GO:0005783; GO:0005789; GO:0016567; GO:0030433; GO:0046872 15600 FUN_023132 2292 2276 2167 3833 2835 NA NA NA NA NA NA NA 15601 FUN_023130 2 3 1 7 9 NA NA NA NA NA NA NA 15602 FUN_037486 1632 1281 823 1152 696 NA NA NA NA NA NA NA 15603 FUN_037487 19 14 13 27 101 NA NA NA NA NA NA NA 15604 FUN_037484 196 90 159 132 68 ptg000026l:10973241-10975519 Q5KR61 1.07e-34 GPI mannosyltransferase 2 (EC 2.4.1.-) (GPI mannosyltransferase II) (GPI-MT-II) (Phosphatidylinositol-glycan biosynthesis class V protein) (PIG-V) Rattus norvegicus (Rat) GPI anchor biosynthetic process [GO:0006506] GO:0000009; GO:0000030; GO:0004376; GO:0005789; GO:0006506; GO:0031501 15605 FUN_037485 1042 503 391 661 545 ptg000026l:10977767-10998342 Q62910 5.27e-33 Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) Rattus norvegicus (Rat) brain development [GO:0007420]; inositol phosphate dephosphorylation [GO:0046855]; learning [GO:0007612]; neurotransmitter transport [GO:0006836]; phosphatidylinositol dephosphorylation [GO:0046856]; phosphatidylinositol metabolic process [GO:0046488]; positive regulation of endosome organization [GO:1904980]; positive regulation of gliogenesis [GO:0014015]; positive regulation of receptor-mediated endocytosis [GO:0048260]; postsynaptic neurotransmitter receptor internalization [GO:0098884]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; response to cytokine [GO:0034097]; response to retinoic acid [GO:0032526]; synaptic vesicle endocytosis [GO:0048488]; synaptic vesicle priming [GO:0016082]; synaptic vesicle transport [GO:0048489]; synaptic vesicle uncoating [GO:0016191] GO:0003723; GO:0004438; GO:0004439; GO:0005737; GO:0006836; GO:0007420; GO:0007612; GO:0008022; GO:0012506; GO:0014015; GO:0016082; GO:0016191; GO:0017124; GO:0030117; GO:0030132; GO:0032526; GO:0032991; GO:0034097; GO:0034595; GO:0043005; GO:0043195; GO:0043812; GO:0044877; GO:0046488; GO:0046855; GO:0046856; GO:0048260; GO:0048471; GO:0048488; GO:0048489; GO:0052658; GO:0097060; GO:0098685; GO:0098688; GO:0098793; GO:0098794; GO:0098884; GO:0098978; GO:0099149; GO:1904980; GO:1990175 15606 FUN_037482 10 0 20 0 114 NA NA NA NA NA NA NA 15607 FUN_037483 755 600 308 807 353 NA NA NA NA NA NA NA 15608 FUN_037480 38 255 54 72 53 NA NA NA NA NA NA NA 15609 FUN_037481 0 0 16 0 43 NA NA NA NA NA NA NA 15610 FUN_037488 3665 3215 1859 3144 1920 ptg000026l:11022325-11029266 Q08BI9 2.85e-30 Calcium uniporter protein, mitochondrial Danio rerio (Zebrafish) (Brachydanio rerio) actin filament organization [GO:0007015]; calcium import into the mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0051259]; regulation of heart contraction [GO:0008016] GO:0005262; GO:0005743; GO:0006851; GO:0007015; GO:0008016; GO:0015292; GO:0019722; GO:0032024; GO:0034704; GO:0036444; GO:0042593; GO:0042802; GO:0043009; GO:0051259; GO:0051560; GO:0051561; GO:0060027; GO:1990246 15611 FUN_037488 3665 3215 1859 3144 1920 ptg000026l:11022325-11029266 Q08BI9 2.41e-24 Calcium uniporter protein, mitochondrial Danio rerio (Zebrafish) (Brachydanio rerio) actin filament organization [GO:0007015]; calcium import into the mitochondrion [GO:0036444]; calcium-mediated signaling [GO:0019722]; chordate embryonic development [GO:0043009]; convergent extension involved in gastrulation [GO:0060027]; glucose homeostasis [GO:0042593]; mitochondrial calcium ion homeostasis [GO:0051560]; mitochondrial calcium ion transmembrane transport [GO:0006851]; positive regulation of insulin secretion [GO:0032024]; positive regulation of mitochondrial calcium ion concentration [GO:0051561]; protein complex oligomerization [GO:0051259]; regulation of heart contraction [GO:0008016] GO:0005262; GO:0005743; GO:0006851; GO:0007015; GO:0008016; GO:0015292; GO:0019722; GO:0032024; GO:0034704; GO:0036444; GO:0042593; GO:0042802; GO:0043009; GO:0051259; GO:0051560; GO:0051561; GO:0060027; GO:1990246 15612 FUN_037489 2581 2317 1320 1808 1505 NA NA NA NA NA NA NA 15613 FUN_006161 18 1388 7 52 3289 NA NA NA NA NA NA NA 15614 FUN_006163 6689 4050 2688 7229 6301 ptg000001l:8590823-8626415 Q8NI27 3.7e-25 THO complex subunit 2 (Tho2) (hTREX120) Homo sapiens (Human) generation of neurons [GO:0048699]; mRNA export from nucleus [GO:0006406]; mRNA processing [GO:0006397]; neuron development [GO:0048666]; poly(A)+ mRNA export from nucleus [GO:0016973]; RNA splicing [GO:0008380]; viral mRNA export from host cell nucleus [GO:0046784] GO:0000346; GO:0000347; GO:0000445; GO:0003729; GO:0005654; GO:0006397; GO:0006406; GO:0008380; GO:0016607; GO:0016973; GO:0046784; GO:0048666; GO:0048699 15615 FUN_006162 8217 11265 8741 18579 8025 NA NA NA NA NA NA NA 15616 FUN_006165 6044 1773 2376 4886 3196 ptg000001l:8634606-8651336 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 15617 FUN_006165 6044 1773 2376 4886 3196 ptg000001l:8634606-8651336 Q6V0I7 0 Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; neurogenesis [GO:0022008] GO:0005509; GO:0005886; GO:0007156; GO:0007157; GO:0021987; GO:0022008; GO:0035329; GO:0070062; GO:0098609 15618 FUN_006164 718 637 446 835 502 NA NA NA NA NA NA NA 15619 FUN_006167 329 152 228 218 224 NA NA NA NA NA NA NA 15620 FUN_006166 2741 1330 1136 1831 1324 ptg000001l:8667131-8673905 Q6DG32 3.89e-41 Solute carrier family 25 member 36-A Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleotide import into mitochondrion [GO:1990519] GO:0000002; GO:0005739; GO:0005743; GO:0015218; GO:1990519 15621 FUN_006169 2817 2464 1738 4253 4574 NA NA NA NA NA NA NA 15622 FUN_006168 176 124 116 253 350 ptg000001l:8684194-8690468 Q07G10 1.61e-42 Alkylated DNA repair protein alkB homolog 8 (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.-, EC 2.1.1.229) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005506; GO:0005634; GO:0005829; GO:0008270; GO:0016300; GO:0030488; GO:0106335 15623 FUN_006168 176 124 116 253 350 ptg000001l:8684194-8690468 Q07G10 1.64e-25 Alkylated DNA repair protein alkB homolog 8 (Probable alpha-ketoglutarate-dependent dioxygenase ABH8) (S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8) (tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8) (EC 2.1.1.-, EC 2.1.1.229) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) tRNA methylation [GO:0030488]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005506; GO:0005634; GO:0005829; GO:0008270; GO:0016300; GO:0030488; GO:0106335 15624 FUN_036281 0 0 0 0 17 NA NA NA NA NA NA NA 15625 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 2.41e-52 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15626 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 3.78e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15627 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 2.1e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15628 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 3.99e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15629 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 4.55e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15630 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 3.51e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15631 FUN_037150 222 122 21 335 61 ptg000026l:6410191-6414028 P0CI65 4.71e-34 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15632 FUN_037151 0 15 0 0 4 NA NA NA NA NA NA NA 15633 FUN_037153 106 0 0 0 0 NA NA NA NA NA NA NA 15634 FUN_037154 51 0 128 16 0 NA NA NA NA NA NA NA 15635 FUN_037155 272 17 0 23 47 ptg000026l:6468704-6471809 P0CI65 8.1e-36 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15636 FUN_037155 272 17 0 23 47 ptg000026l:6468704-6471809 P0CI65 4.17e-34 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15637 FUN_037155 272 17 0 23 47 ptg000026l:6468704-6471809 P0CI65 8.32e-30 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 15638 FUN_037156 153 61 26 42 90 ptg000026l:6486577-6492695 Q7TNH6 7.54e-44 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15639 FUN_037156 153 61 26 42 90 ptg000026l:6486577-6492695 Q7TNH6 5.7e-34 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15640 FUN_037156 153 61 26 42 90 ptg000026l:6486577-6492695 Q7TNH6 2.9e-33 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15641 FUN_037156 153 61 26 42 90 ptg000026l:6486577-6492695 Q7TNH6 2.91e-24 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 15642 FUN_030730 0 0 0 0 11 NA NA NA NA NA NA NA 15643 FUN_032500 609 591 175 1720 1722 NA NA NA NA NA NA NA 15644 FUN_032501 452 399 398 760 841 NA NA NA NA NA NA NA 15645 FUN_032502 293 114 0 98 235 NA NA NA NA NA NA NA 15646 FUN_032503 993 181 1204 1290 386 NA NA NA NA NA NA NA 15647 FUN_032504 54 11 32 79 12 NA NA NA NA NA NA NA 15648 FUN_032505 45 0 0 0 14 NA NA NA NA NA NA NA 15649 FUN_032506 0 8 0 0 43 NA NA NA NA NA NA NA 15650 FUN_032507 23 53 0 30 112 NA NA NA NA NA NA NA 15651 FUN_032508 3 0 0 0 21 NA NA NA NA NA NA NA 15652 FUN_032509 10 0 14 0 4 NA NA NA NA NA NA NA 15653 FUN_023055 84 57 37 131 46 NA NA NA NA NA NA NA 15654 FUN_000088 5 0 16 1 17 ntLink_4:98715-99478 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15655 FUN_001308 833 1099 350 887 862 NA NA NA NA NA NA NA 15656 FUN_001309 1216 746 667 1698 911 NA NA NA NA NA NA NA 15657 FUN_001300 2613 1297 879 2778 2106 NA NA NA NA NA NA NA 15658 FUN_001301 183 67 32 217 131 NA NA NA NA NA NA NA 15659 FUN_001302 3172 2024 1109 3300 2448 NA NA NA NA NA NA NA 15660 FUN_001303 102 58 12 50 35 NA NA NA NA NA NA NA 15661 FUN_001304 31 27 0 0 31 NA NA NA NA NA NA NA 15662 FUN_001305 62 50 25 61 17 NA NA NA NA NA NA NA 15663 FUN_001306 28 21 43 101 98 NA NA NA NA NA NA NA 15664 FUN_001307 127 123 60 100 162 NA NA NA NA NA NA NA 15665 FUN_033671 4465 1900 3244 5671 4235 NA NA NA NA NA NA NA 15666 FUN_033670 3132 1232 2132 4730 2364 NA NA NA NA NA NA NA 15667 FUN_033673 4956 6328 2066 4097 4007 NA NA NA NA NA NA NA 15668 FUN_033672 935 702 463 730 541 ptg000024l:192788-205729 P25100 9.39e-27 Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a) Homo sapiens (Human) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; neuron-glial cell signaling [GO:0150099]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007186; GO:0007188; GO:0007200; GO:0007204; GO:0007267; GO:0008284; GO:0042802; GO:0043410; GO:0045907; GO:0071880; GO:0150099 15669 FUN_033675 2255 1802 1170 1124 1100 NA NA NA NA NA NA NA 15670 FUN_033674 455 305 437 480 516 ptg000024l:218594-220002 A1VBA6 1.24e-22 FMN-dependent NADH:quinone oxidoreductase (EC 1.6.5.-) (Azo-dye reductase) (FMN-dependent NADH-azo compound oxidoreductase) (FMN-dependent NADH-azoreductase) (EC 1.7.1.17) Desulfovibrio vulgaris subsp. vulgaris (strain DP4) NA GO:0009055; GO:0010181; GO:0016652; GO:0016655 15671 FUN_033677 140 49 0 122 85 NA NA NA NA NA NA NA 15672 FUN_033679 24 0 12 14 138 NA NA NA NA NA NA NA 15673 FUN_033678 26 0 0 0 0 ptg000024l:249408-256310 P49013 8.61e-40 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 15674 FUN_033678 26 0 0 0 0 ptg000024l:249408-256310 P49013 1.28e-34 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 15675 FUN_033678 26 0 0 0 0 ptg000024l:249408-256310 P49013 5.86e-34 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 15676 FUN_033678 26 0 0 0 0 ptg000024l:249408-256310 P49013 9.18e-32 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 15677 FUN_033678 26 0 0 0 0 ptg000024l:249408-256310 P49013 4.39e-23 Fibropellin-3 (Epidermal growth factor-related protein 3) (Fibropellin III) (Fibropellin-c) (SpEGF III) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374 15678 FUN_002640 590 50 136 265 220 NA NA NA NA NA NA NA 15679 FUN_002641 334 135 56 409 177 NA NA NA NA NA NA NA 15680 FUN_002642 41 0 0 1 0 NA NA NA NA NA NA NA 15681 FUN_002643 644 32 11 10 7 NA NA NA NA NA NA NA 15682 FUN_002644 720 148 267 1050 602 ntLink_8:4628756-4683967 P14381 1.36e-72 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 15683 FUN_002644 720 148 267 1050 602 ntLink_8:4628756-4683967 P14381 1.36e-72 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 15684 FUN_002644 720 148 267 1050 602 ntLink_8:4628756-4683967 P14381 1.36e-72 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 15685 FUN_002645 191 0 100 75 79 NA NA NA NA NA NA NA 15686 FUN_002646 20 49 37 56 79 NA NA NA NA NA NA NA 15687 FUN_002648 309 420 228 163 148 NA NA NA NA NA NA NA 15688 FUN_002649 241 72 98 225 333 NA NA NA NA NA NA NA 15689 FUN_000081 2 1 4 0 15 ntLink_4:82456-85024 P84239 4.97e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15690 FUN_030739 19 0 11 13 0 NA NA NA NA NA NA NA 15691 FUN_030738 16 0 14 21 8 NA NA NA NA NA NA NA 15692 FUN_019455 31 0 65 28 87 ptg000015l:2449686-2450049 P35061 1.52e-49 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15693 FUN_012739 7529 9083 5464 6388 3700 NA NA NA NA NA NA NA 15694 FUN_001827 9 5 12 4 131 NA NA NA NA NA NA NA 15695 FUN_012737 908 1439 1212 1378 266 ptg000008l:11959043-11972283 P08548 1.53e-28 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 15696 FUN_012731 0 0 15 0 35 NA NA NA NA NA NA NA 15697 FUN_012733 86 111 114 244 182 NA NA NA NA NA NA NA 15698 FUN_006943 2063 2771 2188 2890 2509 NA NA NA NA NA NA NA 15699 FUN_006942 1666 874 994 1523 994 ptg000001l:18596134-18601327 Q91428 3.47e-22 Transcription factor GATA-3 (GATA-binding factor 3) Danio rerio (Zebrafish) (Brachydanio rerio) cardiac muscle tissue regeneration [GO:0061026]; cell fate commitment [GO:0045165]; ectodermal placode development [GO:0071696]; ectodermal placode formation [GO:0060788]; embryonic neurocranium morphogenesis [GO:0048702]; embryonic organ development [GO:0048568]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fin regeneration [GO:0031101]; immune system development [GO:0002520]; negative regulation of transcription by RNA polymerase II [GO:0000122]; otic placode formation [GO:0043049]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neurogenesis [GO:0050769]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of epithelial cell differentiation [GO:0030856]; tissue regeneration [GO:0042246]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000122; GO:0000978; GO:0000981; GO:0002520; GO:0005634; GO:0008270; GO:0008284; GO:0008543; GO:0021514; GO:0030856; GO:0031101; GO:0042246; GO:0043049; GO:0045165; GO:0045944; GO:0048568; GO:0048702; GO:0050769; GO:0060788; GO:0061026; GO:0071696; GO:2001224 15700 FUN_006941 3603 2654 1837 3928 2902 NA NA NA NA NA NA NA 15701 FUN_006940 2477 1328 1081 1785 1564 NA NA NA NA NA NA NA 15702 FUN_016429 4209 2185 1280 4156 1659 ptg000011l:2969514-2971809 Q642M9 3.65e-36 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) (D-xylose 1-dehydrogenase) (D-xylose-NADP dehydrogenase) (EC 1.1.1.179) (Dimeric dihydrodiol dehydrogenase) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0000166; GO:0047115; GO:0047837 15703 FUN_006946 8 14 22 6 59 NA NA NA NA NA NA NA 15704 FUN_006945 0 0 5 0 51 NA NA NA NA NA NA NA 15705 FUN_016425 13916 10941 6619 10780 8506 NA NA NA NA NA NA NA 15706 FUN_016424 10 6 0 0 0 NA NA NA NA NA NA NA 15707 FUN_006949 1540 1655 776 2716 2500 NA NA NA NA NA NA NA 15708 FUN_006948 3812 16056 4890 8520 4833 NA NA NA NA NA NA NA 15709 FUN_016421 2794 1598 1496 1714 1974 NA NA NA NA NA NA NA 15710 FUN_016420 1253 1452 2010 1534 1084 NA NA NA NA NA NA NA 15711 FUN_016423 753 419 471 884 974 NA NA NA NA NA NA NA 15712 FUN_016422 2933 2536 1332 1901 828 ptg000011l:2872837-2874852 P62494 1.11e-49 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 15713 FUN_016422 2933 2536 1332 1901 828 ptg000011l:2872837-2874852 P62494 7.4e-26 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 15714 FUN_009371 65 25 0 42 54 NA NA NA NA NA NA NA 15715 FUN_037328 645 564 774 760 528 NA NA NA NA NA NA NA 15716 FUN_009375 11 0 0 0 37 NA NA NA NA NA NA NA 15717 FUN_004524 221 146 112 300 334 NA NA NA NA NA NA NA 15718 FUN_035149 703 314 4 385 20 ptg000025l:4485557-4487489 Q86W24 1.07e-37 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 15719 FUN_035149 703 314 4 385 20 ptg000025l:4485557-4487489 Q86W24 9.04e-33 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 15720 FUN_035149 703 314 4 385 20 ptg000025l:4485557-4487489 Q86W24 2.6e-32 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 15721 FUN_035149 703 314 4 385 20 ptg000025l:4485557-4487489 Q86W24 6.52e-29 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 15722 FUN_035149 703 314 4 385 20 ptg000025l:4485557-4487489 Q86W24 2.02e-28 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 15723 FUN_035148 1622 396 52 386 387 NA NA NA NA NA NA NA 15724 FUN_009377 210 74 132 150 680 NA NA NA NA NA NA NA 15725 FUN_035141 0 3 10 2 6 NA NA NA NA NA NA NA 15726 FUN_035140 0 3 8 5 5 NA NA NA NA NA NA NA 15727 FUN_035143 248 33 18 102 136 ptg000025l:4429972-4445881 G1T469 4.11e-32 NA NA NA NA 15728 FUN_035142 0 5 0 0 24 NA NA NA NA NA NA NA 15729 FUN_035144 39 12 57 4 39 NA NA NA NA NA NA NA 15730 FUN_035147 117 61 0 0 39 NA NA NA NA NA NA NA 15731 FUN_016396 1197 609 534 884 1433 NA NA NA NA NA NA NA 15732 FUN_016395 1554 891 502 1593 823 NA NA NA NA NA NA NA 15733 FUN_016393 41153 40440 27615 34498 30949 ptg000011l:2604286-2607680 P46222 7.22e-37 60S ribosomal protein L11 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0005730; GO:0005737; GO:0019843; GO:0022625; GO:0022626 15734 FUN_016392 4077 3566 2350 3801 4105 NA NA NA NA NA NA NA 15735 FUN_016399 254 38 204 463 404 NA NA NA NA NA NA NA 15736 FUN_011619 15 0 28 1 80 NA NA NA NA NA NA NA 15737 FUN_002324 0 2 12 8 24 NA NA NA NA NA NA NA 15738 FUN_043298 2805 2162 852 1383 1395 NA NA NA NA NA NA NA 15739 FUN_043299 3092 1523 1661 3837 3022 NA NA NA NA NA NA NA 15740 FUN_043290 6092 4195 2670 4796 3882 ptg000047l:6429301-6465181 A0A1B0GUU1 4.15e-47 Uncharacterized protein C17orf113 Homo sapiens (Human) NA NA 15741 FUN_043290 6092 4195 2670 4796 3882 ptg000047l:6429301-6465181 A0A1B0GUU1 4.15e-47 Uncharacterized protein C17orf113 Homo sapiens (Human) NA NA 15742 FUN_043291 770 335 46 2639 8 NA NA NA NA NA NA NA 15743 FUN_043292 0 0 0 0 6 ptg000047l:6496014-6496905 P49285 3.94e-31 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) (CKA) Gallus gallus (Chicken) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043235; GO:0045820; GO:0046325; GO:1904408 15744 FUN_043293 0 0 43 0 0 NA NA NA NA NA NA NA 15745 FUN_011615 7 1 7 0 30 NA NA NA NA NA NA NA 15746 FUN_043296 194 12 0 0 0 NA NA NA NA NA NA NA 15747 FUN_043297 105 187 264 273 235 NA NA NA NA NA NA NA 15748 FUN_035317 0 26 33 19 44 NA NA NA NA NA NA NA 15749 FUN_011614 0 0 0 7 21 NA NA NA NA NA NA NA 15750 FUN_014937 3567 1904 2044 2750 3392 NA NA NA NA NA NA NA 15751 FUN_013063 0 0 9 25 0 NA NA NA NA NA NA NA 15752 FUN_013060 0 0 0 1 9 NA NA NA NA NA NA NA 15753 FUN_028748 12 4 0 17 20 NA NA NA NA NA NA NA 15754 FUN_013064 0 40 28 7 71 NA NA NA NA NA NA NA 15755 FUN_028744 21 7 0 23 18 NA NA NA NA NA NA NA 15756 FUN_028747 0 0 0 0 71 NA NA NA NA NA NA NA 15757 FUN_028741 41 0 0 0 46 NA NA NA NA NA NA NA 15758 FUN_028740 18 0 0 11 0 NA NA NA NA NA NA NA 15759 FUN_028743 18 0 0 0 0 NA NA NA NA NA NA NA 15760 FUN_028742 6 0 0 0 6 NA NA NA NA NA NA NA 15761 FUN_042653 3780 3630 1806 3450 2866 ptg000039l:799630-807416 Q8TDD5 8.17e-22 Mucolipin-3 (Transient receptor potential channel mucolipin 3) (TRPML3) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; inner ear auditory receptor cell differentiation [GO:0042491]; locomotory behavior [GO:0007626] GO:0000421; GO:0005262; GO:0005765; GO:0005886; GO:0007626; GO:0008289; GO:0016020; GO:0031901; GO:0031902; GO:0042491; GO:0070588; GO:0072345 15762 FUN_042652 1101 483 552 863 981 ptg000039l:790628-797014 Q5ZMV2 1.87e-23 Spindle assembly abnormal protein 6 homolog Gallus gallus (Chicken) centriole replication [GO:0007099] GO:0005737; GO:0005813; GO:0005814; GO:0007099; GO:0098536 15763 FUN_003898 608 350 215 533 316 NA NA NA NA NA NA NA 15764 FUN_042650 59 66 0 149 152 NA NA NA NA NA NA NA 15765 FUN_042657 756 931 612 955 870 ptg000039l:886479-887247 Q66KA5 4.82e-70 Protein YIPF5 (YIP1 family member 5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0005789; GO:0005794; GO:0006888; GO:0015031 15766 FUN_042656 4702 3681 2775 6987 6043 NA NA NA NA NA NA NA 15767 FUN_042655 1716 1108 821 1006 928 NA NA NA NA NA NA NA 15768 FUN_042654 3344 2753 1829 2984 1542 NA NA NA NA NA NA NA 15769 FUN_003892 6535 1458 386 8445 11109 ntLink_8:16559333-16560666 B8VIU6 3.12e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 15770 FUN_003893 1236 651 646 713 739 NA NA NA NA NA NA NA 15771 FUN_003890 334 626 136 32 77 ntLink_8:16539612-16540505 B8VIU6 4.94e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 15772 FUN_003891 227 180 76 192 2111 ntLink_8:16547006-16548353 B8VIU6 1.58e-35 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 15773 FUN_003896 1797 1862 1100 1424 1556 ntLink_8:16600653-16623135 Q61496 1.54e-29 ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Mvh) (Vasa homolog) Mus musculus (Mouse) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; flagellated sperm motility [GO:0030317]; gamete generation [GO:0007276]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of protein localization [GO:0032880]; spermatogenesis [GO:0007283] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0007140; GO:0007141; GO:0007276; GO:0007283; GO:0010529; GO:0016887; GO:0030154; GO:0030317; GO:0032880; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0048471; GO:0071546; GO:0071547; GO:0140693; GO:1990904 15774 FUN_003896 1797 1862 1100 1424 1556 ntLink_8:16600653-16623135 Q61496 2.85e-29 ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Mvh) (Vasa homolog) Mus musculus (Mouse) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; flagellated sperm motility [GO:0030317]; gamete generation [GO:0007276]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of protein localization [GO:0032880]; spermatogenesis [GO:0007283] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0007140; GO:0007141; GO:0007276; GO:0007283; GO:0010529; GO:0016887; GO:0030154; GO:0030317; GO:0032880; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0048471; GO:0071546; GO:0071547; GO:0140693; GO:1990904 15775 FUN_003896 1797 1862 1100 1424 1556 ntLink_8:16600653-16623135 Q61496 1.33e-21 ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Mvh) (Vasa homolog) Mus musculus (Mouse) cell differentiation [GO:0030154]; DNA methylation involved in gamete generation [GO:0043046]; flagellated sperm motility [GO:0030317]; gamete generation [GO:0007276]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of transposition [GO:0010529]; piRNA processing [GO:0034587]; regulation of protein localization [GO:0032880]; spermatogenesis [GO:0007283] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0007140; GO:0007141; GO:0007276; GO:0007283; GO:0010529; GO:0016887; GO:0030154; GO:0030317; GO:0032880; GO:0033391; GO:0034587; GO:0043046; GO:0043186; GO:0048471; GO:0071546; GO:0071547; GO:0140693; GO:1990904 15776 FUN_041500 867 477 166 447 311 NA NA NA NA NA NA NA 15777 FUN_003894 2258 1007 1278 2246 1564 ntLink_8:16573461-16595062 Q2PQH8 1.06e-28 Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)] Canis lupus familiaris (Dog) (Canis familiaris) glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980] GO:0004134; GO:0004135; GO:0005737; GO:0005978; GO:0005980; GO:0102500 15778 FUN_003894 2258 1007 1278 2246 1564 ntLink_8:16573461-16595062 Q2PQH8 1.74e-23 Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)] Canis lupus familiaris (Dog) (Canis familiaris) glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980] GO:0004134; GO:0004135; GO:0005737; GO:0005978; GO:0005980; GO:0102500 15779 FUN_003894 2258 1007 1278 2246 1564 ntLink_8:16573461-16595062 Q2PQH8 3.49e-23 Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)] Canis lupus familiaris (Dog) (Canis familiaris) glycogen biosynthetic process [GO:0005978]; glycogen catabolic process [GO:0005980] GO:0004134; GO:0004135; GO:0005737; GO:0005978; GO:0005980; GO:0102500 15780 FUN_003895 12 21 39 21 0 NA NA NA NA NA NA NA 15781 FUN_030700 17 0 0 0 0 NA NA NA NA NA NA NA 15782 FUN_014873 21 5 61 8 99 NA NA NA NA NA NA NA 15783 FUN_041506 680 584 392 740 327 NA NA NA NA NA NA NA 15784 FUN_041507 1209 1203 710 1246 1006 NA NA NA NA NA NA NA 15785 FUN_035555 237 313 146 229 257 ptg000025l:9046668-9047181 Q96JB1 3.21e-68 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 15786 FUN_009339 0 0 30 13 165 NA NA NA NA NA NA NA 15787 FUN_009338 74 0 95 32 164 NA NA NA NA NA NA NA 15788 FUN_009335 157 120 78 187 307 ptg000004l:5446546-5450297 P25291 6.91e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 15789 FUN_009334 33 23 26 48 39 ptg000004l:5437121-5440131 Q6V0K7 3.86e-22 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 15790 FUN_009337 68 0 17 54 41 NA NA NA NA NA NA NA 15791 FUN_009331 30 13 13 15 73 NA NA NA NA NA NA NA 15792 FUN_009333 0 32 0 0 0 NA NA NA NA NA NA NA 15793 FUN_009332 28 0 0 29 28 NA NA NA NA NA NA NA 15794 FUN_035550 0 0 0 18 41 NA NA NA NA NA NA NA 15795 FUN_035551 92 296 206 57 47 ptg000025l:8977337-8978333 P46616 3.76e-21 Adenosine receptor A2a Cavia porcellus (Guinea pig) regulation of cell communication [GO:0010646]; regulation of signaling [GO:0023051] GO:0001609; GO:0005886; GO:0010646; GO:0023051 15796 FUN_028050 153 15 16 44 29 NA NA NA NA NA NA NA 15797 FUN_001573 1558 410 513 707 1756 NA NA NA NA NA NA NA 15798 FUN_030478 9 0 9 2 40 ptg000023l:10962606-10963369 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15799 FUN_001572 53 1 28 6 15 NA NA NA NA NA NA NA 15800 FUN_001571 24 120 34 0 23 NA NA NA NA NA NA NA 15801 FUN_038202 26 229 0 215 32 NA NA NA NA NA NA NA 15802 FUN_022620 0 7 5 5 6 NA NA NA NA NA NA NA 15803 FUN_022621 20812 14552 7614 11942 9113 NA NA NA NA NA NA NA 15804 FUN_022622 1739 2012 1284 1613 1168 NA NA NA NA NA NA NA 15805 FUN_001570 0 6 32 12 3 NA NA NA NA NA NA NA 15806 FUN_022624 151 102 72 221 200 NA NA NA NA NA NA NA 15807 FUN_022625 5215 4460 2094 3564 3272 NA NA NA NA NA NA NA 15808 FUN_022626 2006 1335 1048 1219 882 NA NA NA NA NA NA NA 15809 FUN_022627 479 147 136 395 174 ptg000016l:11544645-11559554 Q13485 5.12e-42 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4) Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac conduction system development [GO:0003161]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to BMP stimulus [GO:0071773]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [GO:1901522]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of hair follicle development [GO:0051797]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001837; GO:0003148; GO:0003161; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003360; GO:0003682; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0009653; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032924; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0046881; GO:0048589; GO:0048663; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0071773; GO:0072133; GO:0072134; GO:0072520; GO:1901522; GO:1902895; GO:1905305; GO:2000617 15810 FUN_022628 105 54 28 206 151 ptg000016l:11567158-11567650 O70437 2.04e-57 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4) Rattus norvegicus (Rat) adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesendoderm development [GO:0048382]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001822; GO:0001837; GO:0003148; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003279; GO:0003360; GO:0003677; GO:0003682; GO:0003700; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006355; GO:0006357; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0008584; GO:0008585; GO:0009653; GO:0009952; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032991; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042127; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0046881; GO:0048382; GO:0048589; GO:0048663; GO:0048729; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0072133; GO:0072134; GO:0072520; GO:0090575; GO:0140537; GO:1902895; GO:1905305; GO:2000617 15811 FUN_001793 6525 2250 4289 8382 6417 NA NA NA NA NA NA NA 15812 FUN_000306 44 0 20 0 6 NA NA NA NA NA NA NA 15813 FUN_001574 45 19 0 0 174 NA NA NA NA NA NA NA 15814 FUN_001791 426 280 211 882 397 NA NA NA NA NA NA NA 15815 FUN_029905 12 1 7 3 37 NA NA NA NA NA NA NA 15816 FUN_029906 9 3 9 3 44 NA NA NA NA NA NA NA 15817 FUN_001790 50 23 61 51 47 NA NA NA NA NA NA NA 15818 FUN_029900 21 2 8 3 37 NA NA NA NA NA NA NA 15819 FUN_029901 27 3 8 2 18 NA NA NA NA NA NA NA 15820 FUN_029902 12 7 3 2 33 NA NA NA NA NA NA NA 15821 FUN_029903 359 23 219 466 390 NA NA NA NA NA NA NA 15822 FUN_001797 659 708 354 1424 398 NA NA NA NA NA NA NA 15823 FUN_029908 10 3 6 3 36 NA NA NA NA NA NA NA 15824 FUN_029909 8 0 6 6 43 NA NA NA NA NA NA NA 15825 FUN_001796 1056 750 356 875 437 ntLink_6:16184915-16189432 P05183 1.44e-30 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 15826 FUN_001796 1056 750 356 875 437 ntLink_6:16184915-16189432 P05183 8.09e-22 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 15827 FUN_000305 166 128 169 257 91 NA NA NA NA NA NA NA 15828 FUN_001795 79 1 69 294 149 NA NA NA NA NA NA NA 15829 FUN_033160 0 73 0 0 25 NA NA NA NA NA NA NA 15830 FUN_001794 214 93 61 368 227 ntLink_6:16176589-16181925 P05183 4.86e-30 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 15831 FUN_001794 214 93 61 368 227 ntLink_6:16176589-16181925 P05183 4.9e-24 Cytochrome P450 3A2 (EC 1.14.14.1) (CYPIIIA2) (Cytochrome P450-PCN2) (Cytochrome P450/6-beta-A) (Testosterone 6-beta-hydroxylase) Rattus norvegicus (Rat) alkaloid catabolic process [GO:0009822]; estrogen metabolic process [GO:0008210]; heterocycle metabolic process [GO:0046483]; lipid hydroxylation [GO:0002933]; monoterpenoid metabolic process [GO:0016098]; oxidative demethylation [GO:0070989]; retinoic acid metabolic process [GO:0042573]; retinol metabolic process [GO:0042572]; steroid catabolic process [GO:0006706]; steroid metabolic process [GO:0008202]; vitamin D catabolic process [GO:0042369]; xenobiotic catabolic process [GO:0042178]; xenobiotic metabolic process [GO:0006805] GO:0002933; GO:0004497; GO:0005496; GO:0005506; GO:0005737; GO:0005789; GO:0006706; GO:0006805; GO:0008202; GO:0008210; GO:0008395; GO:0008401; GO:0009822; GO:0016098; GO:0016491; GO:0019899; GO:0020037; GO:0030343; GO:0032451; GO:0034875; GO:0042178; GO:0042369; GO:0042572; GO:0042573; GO:0046483; GO:0050649; GO:0062181; GO:0070330; GO:0070576; GO:0070989; GO:0101020; GO:0101021 15832 FUN_040721 0 0 6 0 0 NA NA NA NA NA NA NA 15833 FUN_040723 894 563 253 259 93 ptg000031l:12432949-12433893 Q0IH87 2.09e-57 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 15834 FUN_000304 121 210 496 194 181 NA NA NA NA NA NA NA 15835 FUN_033166 134 0 23 0 48 NA NA NA NA NA NA NA 15836 FUN_009802 0 0 28 0 0 NA NA NA NA NA NA NA 15837 FUN_009800 517 551 384 1039 630 ptg000004l:11743106-11750004 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15838 FUN_009800 517 551 384 1039 630 ptg000004l:11743106-11750004 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15839 FUN_009800 517 551 384 1039 630 ptg000004l:11743106-11750004 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15840 FUN_009800 517 551 384 1039 630 ptg000004l:11743106-11750004 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15841 FUN_009800 517 551 384 1039 630 ptg000004l:11743106-11750004 Q96AY4 5.57e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15842 FUN_009806 12 0 0 0 0 NA NA NA NA NA NA NA 15843 FUN_009805 508 444 415 640 942 ptg000004l:11854789-11860556 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15844 FUN_009805 508 444 415 640 942 ptg000004l:11854789-11860556 Q96AY4 4.76e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15845 FUN_009805 508 444 415 640 942 ptg000004l:11854789-11860556 Q96AY4 2.38e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15846 FUN_009805 508 444 415 640 942 ptg000004l:11854789-11860556 Q96AY4 1.39e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15847 FUN_009804 55 50 40 214 54 ptg000004l:11805410-11811078 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15848 FUN_009804 55 50 40 214 54 ptg000004l:11805410-11811078 Q96AY4 4.24e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15849 FUN_009804 55 50 40 214 54 ptg000004l:11805410-11811078 Q96AY4 3.28e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15850 FUN_009804 55 50 40 214 54 ptg000004l:11805410-11811078 Q96AY4 1.14e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15851 FUN_009804 55 50 40 214 54 ptg000004l:11805410-11811078 Q96AY4 1.66e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 15852 FUN_009809 0 4 29 3 0 NA NA NA NA NA NA NA 15853 FUN_000302 0 60 128 143 73 NA NA NA NA NA NA NA 15854 FUN_024507 122 104 141 201 577 ptg000018l:7320235-7340948 P46023 4.98e-80 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 15855 FUN_024506 0 0 31 0 0 NA NA NA NA NA NA NA 15856 FUN_024503 5 3 6 3 3 NA NA NA NA NA NA NA 15857 FUN_024502 4 0 7 2 0 NA NA NA NA NA NA NA 15858 FUN_024501 155 62 603 72 85 NA NA NA NA NA NA NA 15859 FUN_032261 33 33 18 22 17 NA NA NA NA NA NA NA 15860 FUN_032260 11 58 30 18 65 ptg000023l:30289372-30290407 Q9MYM7 4.45e-29 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 15861 FUN_032263 45 105 123 53 111 ptg000023l:30308839-30310562 Q9MYM7 1.55e-27 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 15862 FUN_032265 25 0 79 22 32 ptg000023l:30328839-30330491 Q9MYM7 7.25e-27 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 15863 FUN_032264 55 260 693 38 82 ptg000023l:30315028-30317572 Q9MYM7 8.33e-27 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 15864 FUN_032267 0 0 0 0 9 NA NA NA NA NA NA NA 15865 FUN_024508 157 131 101 108 93 NA NA NA NA NA NA NA 15866 FUN_000301 39 107 85 68 95 NA NA NA NA NA NA NA 15867 FUN_028059 0 64 11 13 34 NA NA NA NA NA NA NA 15868 FUN_011359 21 0 0 0 20 NA NA NA NA NA NA NA 15869 FUN_011352 57 50 7 7 12 NA NA NA NA NA NA NA 15870 FUN_011353 445 443 153 73 331 NA NA NA NA NA NA NA 15871 FUN_011356 14 68 6 33 0 NA NA NA NA NA NA NA 15872 FUN_011357 4 10 43 730 93 NA NA NA NA NA NA NA 15873 FUN_011354 11 0 0 249 6 NA NA NA NA NA NA NA 15874 FUN_011355 18 0 11 24 23 NA NA NA NA NA NA NA 15875 FUN_028058 0 42 0 14 0 NA NA NA NA NA NA NA 15876 FUN_023999 871 357 301 608 386 NA NA NA NA NA NA NA 15877 FUN_023998 22 2 4 3 11 NA NA NA NA NA NA NA 15878 FUN_023995 44 71 34 105 56 NA NA NA NA NA NA NA 15879 FUN_023994 92 58 47 112 84 NA NA NA NA NA NA NA 15880 FUN_023997 27 4 20 25 76 NA NA NA NA NA NA NA 15881 FUN_023996 130 196 160 68 168 NA NA NA NA NA NA NA 15882 FUN_023991 0 36 0 0 0 NA NA NA NA NA NA NA 15883 FUN_023993 232 118 89 119 95 NA NA NA NA NA NA NA 15884 FUN_023992 147 500 137 440 363 NA NA NA NA NA NA NA 15885 FUN_014801 135 127 69 138 73 NA NA NA NA NA NA NA 15886 FUN_014805 223 262 221 290 226 NA NA NA NA NA NA NA 15887 FUN_014804 74 61 35 43 23 NA NA NA NA NA NA NA 15888 FUN_014807 1499 1035 480 1243 1363 NA NA NA NA NA NA NA 15889 FUN_019830 620 508 562 949 2838 NA NA NA NA NA NA NA 15890 FUN_014809 722 244 440 470 539 ptg000009l:3284827-3295083 Q6JZS3 4.32e-71 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Oryzias latipes (Japanese rice fish) (Japanese killifish) NA GO:0004497; GO:0005506; GO:0005789; GO:0020037; GO:0043231; GO:0070330 15891 FUN_014808 4736 2737 1774 3493 3197 ptg000009l:3268047-3283127 Q6GNY1 5.67e-29 E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase mib1) Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0004842; GO:0005737; GO:0005815; GO:0007219; GO:0008270 15892 FUN_014808 4736 2737 1774 3493 3197 ptg000009l:3268047-3283127 Q6GNY1 5.67e-29 E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase mib1) Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0004842; GO:0005737; GO:0005815; GO:0007219; GO:0008270 15893 FUN_014808 4736 2737 1774 3493 3197 ptg000009l:3268047-3283127 Q6GNY1 1.99e-26 E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase mib1) Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0004842; GO:0005737; GO:0005815; GO:0007219; GO:0008270 15894 FUN_014808 4736 2737 1774 3493 3197 ptg000009l:3268047-3283127 Q6GNY1 1.3e-24 E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase mib1) Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0004842; GO:0005737; GO:0005815; GO:0007219; GO:0008270 15895 FUN_014808 4736 2737 1774 3493 3197 ptg000009l:3268047-3283127 Q6GNY1 3.47e-22 E3 ubiquitin-protein ligase mib1 (EC 2.3.2.27) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase mib1) Xenopus laevis (African clawed frog) Notch signaling pathway [GO:0007219] GO:0004842; GO:0005737; GO:0005815; GO:0007219; GO:0008270 15896 FUN_029802 0 0 0 0 125 NA NA NA NA NA NA NA 15897 FUN_042978 26 49 0 34 39 NA NA NA NA NA NA NA 15898 FUN_016659 89 21 82 40 41 NA NA NA NA NA NA NA 15899 FUN_042972 4717 3038 1908 3219 3187 NA NA NA NA NA NA NA 15900 FUN_016653 552 403 406 865 533 ptg000011l:5903579-5955606 P08953 4.91e-65 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 15901 FUN_016653 552 403 406 865 533 ptg000011l:5903579-5955606 P08953 1.57e-62 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 15902 FUN_016653 552 403 406 865 533 ptg000011l:5903579-5955606 P08953 3.54e-62 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 15903 FUN_016653 552 403 406 865 533 ptg000011l:5903579-5955606 P08953 5.66e-61 Protein toll Drosophila melanogaster (Fruit fly) antifungal innate immune response [GO:0061760]; cell adhesion [GO:0007155]; cell competition in a multicellular organism [GO:0035212]; defense response to Gram-positive bacterium [GO:0050830]; defense response to oomycetes [GO:0002229]; detection of virus [GO:0009597]; dorsal/ventral axis specification [GO:0009950]; heart development [GO:0007507]; innate immune response [GO:0045087]; larval somatic muscle development [GO:0007526]; negative regulation of cell growth [GO:0030308]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of multicellular organism growth [GO:0040015]; positive regulation of antifungal peptide production [GO:0002804]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of hemocyte proliferation [GO:0035208]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of embryonic pattern specification [GO:1902875]; response to tumor cell [GO:0002347]; response to wounding [GO:0009611]; synapse assembly [GO:0007416]; synaptic target inhibition [GO:0016201]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224] GO:0002224; GO:0002225; GO:0002229; GO:0002347; GO:0002804; GO:0004888; GO:0004896; GO:0005769; GO:0005886; GO:0007155; GO:0007416; GO:0007507; GO:0007526; GO:0008063; GO:0009597; GO:0009611; GO:0009897; GO:0009950; GO:0009986; GO:0016201; GO:0019955; GO:0030308; GO:0032154; GO:0035208; GO:0035212; GO:0038023; GO:0040015; GO:0042802; GO:0045087; GO:0045944; GO:0046627; GO:0046790; GO:0050135; GO:0050830; GO:0061760; GO:0061809; GO:0070976; GO:1902875 15904 FUN_016650 95 40 52 63 309 NA NA NA NA NA NA NA 15905 FUN_020976 7 0 44 3 193 NA NA NA NA NA NA NA 15906 FUN_020975 8 0 1186 89 713 NA NA NA NA NA NA NA 15907 FUN_039246 8 0 15 7 69 ptg000027l:15936433-15939278 P35061 5.67e-76 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15908 FUN_039247 2 0 0 0 20 NA NA NA NA NA NA NA 15909 FUN_039245 0 0 17 0 0 NA NA NA NA NA NA NA 15910 FUN_039240 0 0 6 0 10 NA NA NA NA NA NA NA 15911 FUN_039241 6 0 0 0 48 NA NA NA NA NA NA NA 15912 FUN_042974 504 354 230 335 409 NA NA NA NA NA NA NA 15913 FUN_016655 17 0 11 5 99 NA NA NA NA NA NA NA 15914 FUN_039625 15 0 41 2 129 ptg000030l:1891146-1897085 Q6LAF1 3.06e-40 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15915 FUN_012078 164 149 55 151 149 ptg000008l:4857166-4899396 D8VNS8 5.14e-60 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 15916 FUN_012079 2330 777 786 70 15 ptg000008l:4910184-4914293 Q5DU56 8.22e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 15917 FUN_012072 537 444 332 559 306 NA NA NA NA NA NA NA 15918 FUN_012073 149 256 75 249 193 ptg000008l:4822635-4826984 Q3U3W5 1.77e-126 Protein arginine N-methyltransferase 9 (Protein arginine N-methyltransferase 10) (EC 2.1.1.320) Mus musculus (Mouse) mRNA processing [GO:0006397]; peptidyl-arginine methylation [GO:0018216] GO:0005737; GO:0006397; GO:0016274; GO:0018216; GO:0035241; GO:0035243 15919 FUN_012070 64 193 49 110 89 NA NA NA NA NA NA NA 15920 FUN_012071 1544 748 1819 1922 921 NA NA NA NA NA NA NA 15921 FUN_012076 85 27 70 159 44 ptg000008l:4841272-4845092 D8VNS8 4.3e-61 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 15922 FUN_012077 0 4 14 22 2 ptg000008l:4855637-4856306 D8VNS7 5.47e-64 Ryncolin-1 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 15923 FUN_012074 4738 3208 2529 5812 2783 ptg000008l:4827106-4833515 P09139 4.41e-32 Alanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase, mitochondrial) (SPT) (EC 2.6.1.51) Rattus norvegicus (Rat) glycine biosynthetic process, by transamination of glyoxylate [GO:0019265]; glyoxylate catabolic process [GO:0009436]; glyoxylate metabolic process [GO:0046487]; L-alanine catabolic process [GO:0042853]; L-cysteine catabolic process [GO:0019448]; L-serine metabolic process [GO:0006563]; Notch signaling pathway [GO:0007219]; oxalic acid secretion [GO:0046724]; pyruvate biosynthetic process [GO:0042866]; response to cAMP [GO:0051591]; response to glucocorticoid [GO:0051384] GO:0004760; GO:0005739; GO:0005759; GO:0005777; GO:0005782; GO:0006563; GO:0007219; GO:0008453; GO:0008483; GO:0009436; GO:0016597; GO:0019265; GO:0019448; GO:0030170; GO:0042802; GO:0042803; GO:0042853; GO:0042866; GO:0043621; GO:0046487; GO:0046724; GO:0051384; GO:0051591 15924 FUN_012075 2256 1640 1270 3782 1777 NA NA NA NA NA NA NA 15925 FUN_015867 3462 935 237 4456 100 NA NA NA NA NA NA NA 15926 FUN_000226 416 238 217 230 462 NA NA NA NA NA NA NA 15927 FUN_010042 0 22 0 0 31 NA NA NA NA NA NA NA 15928 FUN_015995 101757 135393 77138 101820 64296 NA NA NA NA NA NA NA 15929 FUN_005120 100235 142748 67242 92698 53542 ntLink_8:31312188-31316766 P24049 1.01e-30 60S ribosomal protein L17 (Amino acid starvation-induced protein) (ASI) (L23) Rattus norvegicus (Rat) cellular response to amino acid starvation [GO:0034198]; cytoplasmic translation [GO:0002181]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; response to amino acid starvation [GO:1990928] GO:0002181; GO:0003735; GO:0005634; GO:0005844; GO:0022625; GO:0022626; GO:0031672; GO:0034198; GO:0045202; GO:0070180; GO:1900087; GO:1990928 15930 FUN_022835 84 77 159 127 3 NA NA NA NA NA NA NA 15931 FUN_000227 393 179 237 433 445 NA NA NA NA NA NA NA 15932 FUN_022836 26 0 0 12 5 NA NA NA NA NA NA NA 15933 FUN_038268 723 325 418 553 479 ptg000027l:4916384-4940602 Q9NBX4 1.75e-25 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 15934 FUN_024498 101 0 116 72 351 NA NA NA NA NA NA NA 15935 FUN_023238 329 167 274 327 413 NA NA NA NA NA NA NA 15936 FUN_023239 762 542 331 643 840 NA NA NA NA NA NA NA 15937 FUN_023230 1030 1220 530 1145 1310 NA NA NA NA NA NA NA 15938 FUN_023231 1870 1248 928 1938 1530 NA NA NA NA NA NA NA 15939 FUN_023233 1034 782 253 879 815 ptg000017l:5317941-5320980 Q7KZN9 6.13e-23 Cytochrome c oxidase assembly protein COX15 homolog Homo sapiens (Human) cellular respiration [GO:0045333]; heme A biosynthetic process [GO:0006784]; heme biosynthetic process [GO:0006783]; mitochondrial electron transport, cytochrome c to oxygen [GO:0006123]; proton transmembrane transport [GO:1902600]; respiratory chain complex IV assembly [GO:0008535]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0004129; GO:0005654; GO:0005739; GO:0005743; GO:0005746; GO:0006123; GO:0006783; GO:0006784; GO:0007585; GO:0008535; GO:0016627; GO:0016653; GO:0020037; GO:0045333; GO:0060090; GO:0070069; GO:1902600 15940 FUN_023234 0 25 55 81 72 NA NA NA NA NA NA NA 15941 FUN_023235 34 194 179 310 1144 NA NA NA NA NA NA NA 15942 FUN_023236 17567 20101 10361 13511 7647 ptg000017l:5333265-5348870 O43422 2.91e-72 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 15943 FUN_023237 4957 2941 3016 4404 3731 NA NA NA NA NA NA NA 15944 FUN_020756 10 3 3 76 38 NA NA NA NA NA NA NA 15945 FUN_006593 4 0 2 8 8 NA NA NA NA NA NA NA 15946 FUN_014020 25 0 0 44 7 NA NA NA NA NA NA NA 15947 FUN_014027 0 0 0 0 8 NA NA NA NA NA NA NA 15948 FUN_014026 0 0 0 0 66 NA NA NA NA NA NA NA 15949 FUN_014025 130 150 67 0 0 NA NA NA NA NA NA NA 15950 FUN_014029 810 537 405 742 873 NA NA NA NA NA NA NA 15951 FUN_009479 0 0 0 0 8 NA NA NA NA NA NA NA 15952 FUN_009472 13 0 18 16 283 NA NA NA NA NA NA NA 15953 FUN_009473 13 0 0 6 67 NA NA NA NA NA NA NA 15954 FUN_009470 0 0 0 15 0 NA NA NA NA NA NA NA 15955 FUN_009471 0 0 30 0 49 NA NA NA NA NA NA NA 15956 FUN_009477 0 0 37 8 123 ptg000004l:7378900-7454423 P14381 1.63e-98 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 15957 FUN_009474 25 0 0 18 0 NA NA NA NA NA NA NA 15958 FUN_031697 229 194 79 72 252 NA NA NA NA NA NA NA 15959 FUN_026469 1976 701 1649 1186 1129 ptg000020l:9259447-9292279 P0CT40 3.44e-55 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 15960 FUN_026469 1976 701 1649 1186 1129 ptg000020l:9259447-9292279 P0CT40 3.44e-55 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 15961 FUN_026462 19 590 0 3069 10 NA NA NA NA NA NA NA 15962 FUN_026463 0 0 0 0 48 NA NA NA NA NA NA NA 15963 FUN_026461 0 0 0 33 0 NA NA NA NA NA NA NA 15964 FUN_026466 78 40 20 63 0 NA NA NA NA NA NA NA 15965 FUN_026467 0 24 113 186 70 NA NA NA NA NA NA NA 15966 FUN_026464 0 6 2 8 0 NA NA NA NA NA NA NA 15967 FUN_026465 0 0 0 586 0 NA NA NA NA NA NA NA 15968 FUN_022549 79 197 36 223 75 NA NA NA NA NA NA NA 15969 FUN_022548 157 122 37 62 72 NA NA NA NA NA NA NA 15970 FUN_022541 373 198 252 331 339 NA NA NA NA NA NA NA 15971 FUN_022540 6641 4651 3346 4858 4343 NA NA NA NA NA NA NA 15972 FUN_022543 215 294 120 159 184 NA NA NA NA NA NA NA 15973 FUN_022542 408 163 236 273 425 NA NA NA NA NA NA NA 15974 FUN_022545 307 281 141 393 165 NA NA NA NA NA NA NA 15975 FUN_022544 1419 523 492 760 924 NA NA NA NA NA NA NA 15976 FUN_022547 173 67 68 95 31 NA NA NA NA NA NA NA 15977 FUN_022546 196 71 246 376 290 NA NA NA NA NA NA NA 15978 FUN_010697 1576 1508 722 480 766 ptg000007l:1779076-1780318 P27808 3.8e-142 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I) Mus musculus (Mouse) in utero embryonic development [GO:0001701]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279]; UDP-N-acetylglucosamine catabolic process [GO:0006049] GO:0000139; GO:0001701; GO:0003827; GO:0005794; GO:0006049; GO:0006486; GO:0006487; GO:0008375; GO:0018279; GO:0030145; GO:0048471 15979 FUN_019193 0 0 0 1 11 NA NA NA NA NA NA NA 15980 FUN_019194 88 1 3 0 0 NA NA NA NA NA NA NA 15981 FUN_019195 15 0 16 4 159 ptg000012l:18198887-18199204 Q6LAF1 3.5e-53 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15982 FUN_019197 60 1 58 2 244 ptg000012l:18209381-18209810 P84239 1.09e-88 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15983 FUN_019198 16 9 21 49 91 ptg000012l:18210687-18212230 P35067 2.37e-56 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 15984 FUN_041576 299 181 154 105 148 NA NA NA NA NA NA NA 15985 FUN_004913 477 442 181 284 279 ntLink_8:28660251-28662972 Q99M01 5.18e-58 Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033] GO:0000049; GO:0004826; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0006432; GO:0008033 15986 FUN_004913 477 442 181 284 279 ntLink_8:28660251-28662972 Q99M01 9.29e-27 Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033] GO:0000049; GO:0004826; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0006432; GO:0008033 15987 FUN_004913 477 442 181 284 279 ntLink_8:28660251-28662972 Q99M01 2.64e-25 Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) Mus musculus (Mouse) phenylalanyl-tRNA aminoacylation [GO:0006432]; tRNA processing [GO:0008033] GO:0000049; GO:0004826; GO:0005524; GO:0005737; GO:0005739; GO:0005759; GO:0006432; GO:0008033 15988 FUN_021168 0 32 0 0 0 NA NA NA NA NA NA NA 15989 FUN_021169 28 1 17 28 15 NA NA NA NA NA NA NA 15990 FUN_021166 1 2 0 6 0 NA NA NA NA NA NA NA 15991 FUN_021167 17 28 36 41 61 NA NA NA NA NA NA NA 15992 FUN_021165 0 0 0 59 44 NA NA NA NA NA NA NA 15993 FUN_021161 0 16 0 0 0 NA NA NA NA NA NA NA 15994 FUN_017839 2029 1353 1162 3573 2372 NA NA NA NA NA NA NA 15995 FUN_017838 3870 1909 1978 3377 3319 NA NA NA NA NA NA NA 15996 FUN_018829 259 20 12 24 4 NA NA NA NA NA NA NA 15997 FUN_018828 16 0 21 21 0 NA NA NA NA NA NA NA 15998 FUN_018827 4 0 2 20 0 NA NA NA NA NA NA NA 15999 FUN_018826 539 239 261 516 234 ptg000012l:14046873-14051395 D2GXS7 8.05e-65 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Ailuropoda melanoleuca (Giant panda) regulation of neuron apoptotic process [GO:0043523] GO:0004842; GO:0005737; GO:0008270; GO:0043523 16000 FUN_018826 539 239 261 516 234 ptg000012l:14046873-14051395 D2GXS7 1.15e-23 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Ailuropoda melanoleuca (Giant panda) regulation of neuron apoptotic process [GO:0043523] GO:0004842; GO:0005737; GO:0008270; GO:0043523 16001 FUN_017833 4157 2982 1767 3109 3421 NA NA NA NA NA NA NA 16002 FUN_017832 3281 2958 3115 4325 3932 NA NA NA NA NA NA NA 16003 FUN_017835 3300 1609 967 1552 1521 NA NA NA NA NA NA NA 16004 FUN_018822 232 395 233 681 229 NA NA NA NA NA NA NA 16005 FUN_018821 194 342 118 136 15 NA NA NA NA NA NA NA 16006 FUN_017836 0 0 0 0 17 NA NA NA NA NA NA NA 16007 FUN_035389 462 383 211 529 464 NA NA NA NA NA NA NA 16008 FUN_035388 384 215 187 540 503 NA NA NA NA NA NA NA 16009 FUN_035387 62 0 0 52 57 NA NA NA NA NA NA NA 16010 FUN_035386 111 23 34 62 64 NA NA NA NA NA NA NA 16011 FUN_035385 108 69 92 163 204 NA NA NA NA NA NA NA 16012 FUN_035384 31 0 0 27 15 NA NA NA NA NA NA NA 16013 FUN_035383 58 0 68 95 146 NA NA NA NA NA NA NA 16014 FUN_035382 11 3 12 3 26 NA NA NA NA NA NA NA 16015 FUN_035381 13 24 11 0 0 NA NA NA NA NA NA NA 16016 FUN_038388 265 203 165 321 300 NA NA NA NA NA NA NA 16017 FUN_038389 1460 832 954 1442 1308 NA NA NA NA NA NA NA 16018 FUN_038384 9 0 0 0 0 NA NA NA NA NA NA NA 16019 FUN_038385 525 220 269 630 632 ptg000027l:6492905-6518297 P16065 1.9e-44 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 16020 FUN_038385 525 220 269 630 632 ptg000027l:6492905-6518297 P16065 1.9e-44 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 16021 FUN_038385 525 220 269 630 632 ptg000027l:6492905-6518297 P16065 1.9e-44 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 16022 FUN_038385 525 220 269 630 632 ptg000027l:6492905-6518297 P16065 1.9e-44 Speract receptor (EC 4.6.1.2) (Guanylate cyclase) Strongylocentrotus purpuratus (Purple sea urchin) cGMP biosynthetic process [GO:0006182]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0007165; GO:0007168; GO:0035556 16023 FUN_038386 3555 4371 2338 15405 7488 NA NA NA NA NA NA NA 16024 FUN_038387 1134 608 827 1207 1105 NA NA NA NA NA NA NA 16025 FUN_038380 615 261 214 904 489 NA NA NA NA NA NA NA 16026 FUN_038381 2647 1871 960 1428 820 NA NA NA NA NA NA NA 16027 FUN_038382 132 103 74 79 52 ptg000027l:6456245-6463845 Q90922 1.36e-101 Netrin-1 Gallus gallus (Chicken) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005829; GO:0006930; GO:0007097; GO:0007265; GO:0008045; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030517; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0061643; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 16028 FUN_038382 132 103 74 79 52 ptg000027l:6456245-6463845 Q90922 4.41e-21 Netrin-1 Gallus gallus (Chicken) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005654; GO:0005829; GO:0006930; GO:0007097; GO:0007265; GO:0008045; GO:0009887; GO:0009888; GO:0014009; GO:0015629; GO:0016358; GO:0019724; GO:0030517; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0061643; GO:0071944; GO:0097475; GO:0098609; GO:1903975; GO:2000147 16029 FUN_038383 100 71 51 61 289 NA NA NA NA NA NA NA 16030 FUN_031862 167 164 97 142 121 NA NA NA NA NA NA NA 16031 FUN_031863 228 121 248 252 258 NA NA NA NA NA NA NA 16032 FUN_031860 5632 3098 2657 4720 6201 ptg000023l:26124814-26135590 Q86UA1 4.96e-51 Pre-mRNA-processing factor 39 (PRP39 homolog) Homo sapiens (Human) mRNA 5'-splice site recognition [GO:0000395] GO:0000243; GO:0000395; GO:0005685; GO:0071004 16033 FUN_031861 666 809 780 442 275 NA NA NA NA NA NA NA 16034 FUN_031866 106 220 44 79 1223 NA NA NA NA NA NA NA 16035 FUN_031867 505 240 149 461 454 NA NA NA NA NA NA NA 16036 FUN_031864 1241 44 564 533 1008 NA NA NA NA NA NA NA 16037 FUN_031865 17 0 16 0 51 NA NA NA NA NA NA NA 16038 FUN_039141 0 7 0 6 4 NA NA NA NA NA NA NA 16039 FUN_031868 456 143 154 298 591 NA NA NA NA NA NA NA 16040 FUN_031869 672 434 313 478 575 NA NA NA NA NA NA NA 16041 FUN_010906 11545 1629 2053 977 5990 ptg000007l:4100576-4101413 R1CW23 9.46e-105 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 16042 FUN_000547 254 253 173 275 89 ntLink_6:4240200-4241886 Q54WT7 4.27e-22 Cystinosin homolog Dictyostelium discoideum (Social amoeba) L-cystine transport [GO:0015811] GO:0005765; GO:0005774; GO:0015184; GO:0015293; GO:0015811 16043 FUN_030403 8 0 9 0 27 ptg000023l:10782761-10783524 P84239 1.65e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16044 FUN_030406 5 0 11 1 34 ptg000023l:10790864-10791627 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16045 FUN_030405 4 0 3 0 16 ptg000023l:10786812-10787575 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16046 FUN_021782 8 0 0 0 25 NA NA NA NA NA NA NA 16047 FUN_021785 0 0 7 0 17 NA NA NA NA NA NA NA 16048 FUN_038656 9 0 0 0 0 NA NA NA NA NA NA NA 16049 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 7.6e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16050 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 2.88e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16051 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 1.29e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16052 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 6.49e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16053 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 2.42e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16054 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 7.35e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16055 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 6.36e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16056 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 2.35e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16057 FUN_038657 154 66 14 33 74 ptg000027l:9846370-9854206 Q96AY4 1.12e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16058 FUN_004972 0 0 0 8 9 NA NA NA NA NA NA NA 16059 FUN_038655 32 18 20 0 67 ptg000027l:9821827-9826664 Q1LYL8 2.75e-38 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 16060 FUN_038652 136 19 0 68 0 NA NA NA NA NA NA NA 16061 FUN_038651 97 59 62 52 127 ptg000027l:9798473-9803202 Q96AY4 1.65e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16062 FUN_038651 97 59 62 52 127 ptg000027l:9798473-9803202 Q96AY4 1.57e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16063 FUN_038651 97 59 62 52 127 ptg000027l:9798473-9803202 Q96AY4 6.03e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16064 FUN_038651 97 59 62 52 127 ptg000027l:9798473-9803202 Q96AY4 1.43e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16065 FUN_038651 97 59 62 52 127 ptg000027l:9798473-9803202 Q96AY4 1.59e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16066 FUN_004978 250 105 386 210 153 NA NA NA NA NA NA NA 16067 FUN_004979 426 117 383 504 644 NA NA NA NA NA NA NA 16068 FUN_038658 138 36 15 75 99 ptg000027l:9855429-9863640 Q5RCY5 1.21e-36 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 16069 FUN_038659 1245 1091 372 1548 879 ptg000027l:9864130-9888433 Q5RCY5 3.04e-30 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 16070 FUN_039143 0 1 6 0 0 NA NA NA NA NA NA NA 16071 FUN_024547 0 216 0 289 4 NA NA NA NA NA NA NA 16072 FUN_024546 499 897 215 1075 394 NA NA NA NA NA NA NA 16073 FUN_009506 2 0 1 0 9 NA NA NA NA NA NA NA 16074 FUN_008136 27 0 0 4 3 NA NA NA NA NA NA NA 16075 FUN_000540 8 0 1 11 0 NA NA NA NA NA NA NA 16076 FUN_020781 21 0 39 0 51 NA NA NA NA NA NA NA 16077 FUN_006848 0 14 44 0 9 NA NA NA NA NA NA NA 16078 FUN_020785 0 8 0 4 7 NA NA NA NA NA NA NA 16079 FUN_020787 5 2 5 26 23 NA NA NA NA NA NA NA 16080 FUN_020786 11 7 3 13 19 NA NA NA NA NA NA NA 16081 FUN_020789 0 0 0 0 28 NA NA NA NA NA NA NA 16082 FUN_020788 14 1 1 0 89 NA NA NA NA NA NA NA 16083 FUN_010699 831 444 602 1584 1734 NA NA NA NA NA NA NA 16084 FUN_005645 1417 39 108 39 57 NA NA NA NA NA NA NA 16085 FUN_006660 176 107 61 421 570 NA NA NA NA NA NA NA 16086 FUN_036126 0 0 0 0 47 NA NA NA NA NA NA NA 16087 FUN_028792 0 0 0 0 10 NA NA NA NA NA NA NA 16088 FUN_036124 1073 535 548 954 1290 ptg000025l:15588500-15596741 Q9UK23 8.98e-64 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC 3.1.4.45) (Mannose 6-phosphate-uncovering enzyme) (Phosphodiester alpha-GlcNAcase) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; lysosome organization [GO:0007040]; protein glycosylation [GO:0006486]; protein modification process [GO:0036211]; protein targeting to lysosome [GO:0006622]; secretion of lysosomal enzymes [GO:0033299] GO:0003944; GO:0005975; GO:0006486; GO:0006622; GO:0007040; GO:0016020; GO:0032580; GO:0033299; GO:0036211 16089 FUN_036125 106 362 190 212 763 NA NA NA NA NA NA NA 16090 FUN_036122 61 22 21 30 14 ptg000025l:15572313-15572969 Q6LAF1 8.04e-51 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16091 FUN_036123 334 181 93 258 244 ptg000025l:15575934-15588376 P35061 1e-57 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16092 FUN_005644 125 0 23 16 4 NA NA NA NA NA NA NA 16093 FUN_036121 0 2 5 0 30 ptg000025l:15571383-15572228 P84239 2.86e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16094 FUN_036128 441 539 154 287 332 NA NA NA NA NA NA NA 16095 FUN_036129 2033 1557 376 1234 1158 NA NA NA NA NA NA NA 16096 FUN_037839 1538 449 1135 1287 928 ptg000026l:14222795-14236399 A7E305 3.8e-69 Zinc finger SWIM domain-containing protein 8 Bos taurus (Bovine) positive regulation of miRNA catabolic process [GO:2000627]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005829; GO:0008270; GO:0016567; GO:0031462; GO:0031463; GO:0043161; GO:1990756; GO:2000627 16097 FUN_037839 1538 449 1135 1287 928 ptg000026l:14222795-14236399 A7E305 1.05e-38 Zinc finger SWIM domain-containing protein 8 Bos taurus (Bovine) positive regulation of miRNA catabolic process [GO:2000627]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005829; GO:0008270; GO:0016567; GO:0031462; GO:0031463; GO:0043161; GO:1990756; GO:2000627 16098 FUN_037839 1538 449 1135 1287 928 ptg000026l:14222795-14236399 A7E305 1.24e-31 Zinc finger SWIM domain-containing protein 8 Bos taurus (Bovine) positive regulation of miRNA catabolic process [GO:2000627]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005829; GO:0008270; GO:0016567; GO:0031462; GO:0031463; GO:0043161; GO:1990756; GO:2000627 16099 FUN_037839 1538 449 1135 1287 928 ptg000026l:14222795-14236399 A7E305 3.05e-31 Zinc finger SWIM domain-containing protein 8 Bos taurus (Bovine) positive regulation of miRNA catabolic process [GO:2000627]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567] GO:0005829; GO:0008270; GO:0016567; GO:0031462; GO:0031463; GO:0043161; GO:1990756; GO:2000627 16100 FUN_026335 30 0 3 0 0 NA NA NA NA NA NA NA 16101 FUN_012189 506 31 230 796 658 NA NA NA NA NA NA NA 16102 FUN_037833 33 51 53 90 26 NA NA NA NA NA NA NA 16103 FUN_037832 6 2 0 0 17 NA NA NA NA NA NA NA 16104 FUN_037831 378 292 544 1099 713 NA NA NA NA NA NA NA 16105 FUN_037830 168 159 235 501 318 NA NA NA NA NA NA NA 16106 FUN_037837 1054 606 339 823 678 NA NA NA NA NA NA NA 16107 FUN_037836 7125 8744 2970 4686 4175 ptg000026l:14199692-14202762 P53358 1.12e-22 Proliferating cell nuclear antigen (PCNA) (Cyclin) Styela clava (Sea squirt) DNA replication [GO:0006260]; regulation of DNA replication [GO:0006275] GO:0003677; GO:0005634; GO:0006260; GO:0006275; GO:0030337 16108 FUN_037835 3449 2297 1546 2690 2252 NA NA NA NA NA NA NA 16109 FUN_028797 0 0 0 8 6 NA NA NA NA NA NA NA 16110 FUN_027788 29 0 0 0 0 ptg000021l:10853303-10886734 P14381 5.89e-104 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 16111 FUN_027788 29 0 0 0 0 ptg000021l:10853303-10886734 P14381 5.89e-104 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 16112 FUN_027789 14 25 26 0 0 NA NA NA NA NA NA NA 16113 FUN_028795 8426 4029 3947 8698 8159 NA NA NA NA NA NA NA 16114 FUN_027780 1488 628 222 1204 291 NA NA NA NA NA NA NA 16115 FUN_027781 143 17 0 194 64 NA NA NA NA NA NA NA 16116 FUN_027782 0 0 0 10 16 NA NA NA NA NA NA NA 16117 FUN_027783 100 0 0 0 19 NA NA NA NA NA NA NA 16118 FUN_009507 18 0 0 0 31 NA NA NA NA NA NA NA 16119 FUN_027256 1111 505 531 1337 488 ptg000021l:2494404-2506187 Q7RTR2 6.66e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16120 FUN_027256 1111 505 531 1337 488 ptg000021l:2494404-2506187 Q7RTR2 2.04e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16121 FUN_027256 1111 505 531 1337 488 ptg000021l:2494404-2506187 Q7RTR2 6.12e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16122 FUN_027256 1111 505 531 1337 488 ptg000021l:2494404-2506187 Q7RTR2 3.41e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16123 FUN_027256 1111 505 531 1337 488 ptg000021l:2494404-2506187 Q7RTR2 5.12e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16124 FUN_027256 1111 505 531 1337 488 ptg000021l:2494404-2506187 Q7RTR2 5.29e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16125 FUN_027257 600 21 323 36 6 NA NA NA NA NA NA NA 16126 FUN_027254 4211 2118 1359 5821 2564 ptg000021l:2358073-2477837 Q7RTR2 3.84e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16127 FUN_027254 4211 2118 1359 5821 2564 ptg000021l:2358073-2477837 Q7RTR2 1.81e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16128 FUN_027252 217 557 285 715 635 ptg000021l:2288513-2339621 P04323 2.55e-62 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 16129 FUN_027251 23 0 22 0 59 NA NA NA NA NA NA NA 16130 FUN_035227 3472 2459 1495 3917 3209 NA NA NA NA NA NA NA 16131 FUN_037047 62 73 70 23 70 NA NA NA NA NA NA NA 16132 FUN_034003 29 20 22 25 21 NA NA NA NA NA NA NA 16133 FUN_005318 2 0 3 0 6 NA NA NA NA NA NA NA 16134 FUN_034002 30 0 152 0 206 NA NA NA NA NA NA NA 16135 FUN_005313 4816 3651 2365 3959 3290 ntLink_8:33904629-33913098 Q9JIT3 7.26e-56 Transducin-like enhancer protein 3 (rTLE3) Rattus norvegicus (Rat) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of DNA-templated transcription [GO:0006355]; Wnt signaling pathway [GO:0016055] GO:0003714; GO:0005634; GO:0005667; GO:0006355; GO:0016055; GO:0090090; GO:0120163; GO:1990907 16136 FUN_005313 4816 3651 2365 3959 3290 ntLink_8:33904629-33913098 Q9JIT3 1.43e-26 Transducin-like enhancer protein 3 (rTLE3) Rattus norvegicus (Rat) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of DNA-templated transcription [GO:0006355]; Wnt signaling pathway [GO:0016055] GO:0003714; GO:0005634; GO:0005667; GO:0006355; GO:0016055; GO:0090090; GO:0120163; GO:1990907 16137 FUN_005313 4816 3651 2365 3959 3290 ntLink_8:33904629-33913098 Q9JIT3 1.69e-21 Transducin-like enhancer protein 3 (rTLE3) Rattus norvegicus (Rat) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cold-induced thermogenesis [GO:0120163]; regulation of DNA-templated transcription [GO:0006355]; Wnt signaling pathway [GO:0016055] GO:0003714; GO:0005634; GO:0005667; GO:0006355; GO:0016055; GO:0090090; GO:0120163; GO:1990907 16138 FUN_005312 73 88 138 113 186 NA NA NA NA NA NA NA 16139 FUN_005311 0 0 0 6 7 NA NA NA NA NA NA NA 16140 FUN_005317 4235 6938 3403 5394 4931 NA NA NA NA NA NA NA 16141 FUN_034001 42 0 271 66 591 NA NA NA NA NA NA NA 16142 FUN_005315 2768 1632 1348 2760 3366 NA NA NA NA NA NA NA 16143 FUN_005314 780 329 365 488 469 NA NA NA NA NA NA NA 16144 FUN_016977 224 72 229 181 75 NA NA NA NA NA NA NA 16145 FUN_016976 3362 4346 1308 2365 1330 NA NA NA NA NA NA NA 16146 FUN_016975 1408 4998 1164 2704 2249 NA NA NA NA NA NA NA 16147 FUN_018473 116 156 0 40 65 NA NA NA NA NA NA NA 16148 FUN_016973 316 430 381 136 259 NA NA NA NA NA NA NA 16149 FUN_016972 1280 1496 1202 1102 493 NA NA NA NA NA NA NA 16150 FUN_016971 137 101 347 123 185 NA NA NA NA NA NA NA 16151 FUN_016970 479 671 339 933 232 NA NA NA NA NA NA NA 16152 FUN_034007 662 347 351 751 562 ptg000024l:3623580-3633261 Q9EPL0 2.16e-39 Xylosyltransferase 2 (EC 2.4.2.26) (Peptide O-xylosyltransferase 2) (Xylosyltransferase II) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0000287; GO:0005615; GO:0005794; GO:0006024; GO:0015012; GO:0030145; GO:0030158; GO:0030166; GO:0030206; GO:0030210; GO:0050650 16153 FUN_034007 662 347 351 751 562 ptg000024l:3623580-3633261 Q9EPL0 1.55e-21 Xylosyltransferase 2 (EC 2.4.2.26) (Peptide O-xylosyltransferase 2) (Xylosyltransferase II) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0000287; GO:0005615; GO:0005794; GO:0006024; GO:0015012; GO:0030145; GO:0030158; GO:0030166; GO:0030206; GO:0030210; GO:0050650 16154 FUN_034007 662 347 351 751 562 ptg000024l:3623580-3633261 Q9EPL0 4.61e-21 Xylosyltransferase 2 (EC 2.4.2.26) (Peptide O-xylosyltransferase 2) (Xylosyltransferase II) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0000287; GO:0005615; GO:0005794; GO:0006024; GO:0015012; GO:0030145; GO:0030158; GO:0030166; GO:0030206; GO:0030210; GO:0050650 16155 FUN_003412 0 0 0 0 10 NA NA NA NA NA NA NA 16156 FUN_016978 277 245 241 305 266 NA NA NA NA NA NA NA 16157 FUN_034005 19 21 24 31 25 NA NA NA NA NA NA NA 16158 FUN_034004 2847 2910 1332 1113 893 NA NA NA NA NA NA NA 16159 FUN_006469 43 77 2 144 136 NA NA NA NA NA NA NA 16160 FUN_006460 2642 79 0 244 153 NA NA NA NA NA NA NA 16161 FUN_006461 234 1866 460 978 1487 NA NA NA NA NA NA NA 16162 FUN_006464 95 68 131 450 142 NA NA NA NA NA NA NA 16163 FUN_006465 44 16 43 71 17 NA NA NA NA NA NA NA 16164 FUN_006466 32 0 105 78 0 NA NA NA NA NA NA NA 16165 FUN_006467 208 0 0 135 71 NA NA NA NA NA NA NA 16166 FUN_032711 0 218 219 111 1254 ptg000023l:35132347-35134646 Q6DEY7 7.15e-25 Embryonic polyadenylate-binding protein (Embryonic poly(A)-binding protein) (ePABP) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chordate embryonic development [GO:0043009]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; translation [GO:0006412] GO:0005737; GO:0006397; GO:0006412; GO:0008143; GO:0031370; GO:0043009; GO:0043621; GO:0048255; GO:0060212 16167 FUN_032710 107 47 385 109 1057 ptg000023l:35125004-35131665 P29341 9.92e-23 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 16168 FUN_032710 107 47 385 109 1057 ptg000023l:35125004-35131665 P29341 1.23e-21 Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) Mus musculus (Mouse) CRD-mediated mRNA stabilization [GO:0070934]; mRNA processing [GO:0006397]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA splicing [GO:0008380]; RNA-mediated gene silencing [GO:0031047] GO:0000184; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0006397; GO:0008022; GO:0008143; GO:0008266; GO:0008380; GO:0010494; GO:0030027; GO:0030425; GO:0031047; GO:0031252; GO:0036464; GO:0045202; GO:0060213; GO:0070934; GO:0071013; GO:0106002; GO:1900152; GO:1900153; GO:1990124; GO:1990904; GO:2000623; GO:2000767 16169 FUN_032713 39 0 50 0 26 NA NA NA NA NA NA NA 16170 FUN_032712 250 454 237 964 449 ptg000023l:35140456-35160149 P11369 4.57e-40 LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Mus musculus (Mouse) DNA recombination [GO:0006310] GO:0003964; GO:0004519; GO:0006310; GO:0046872 16171 FUN_032715 1740 1780 742 1769 4340 ptg000023l:35177399-35186047 P21187 2.09e-31 Polyadenylate-binding protein (PABP) (Poly(A)-binding protein) Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; dorsal/ventral pattern formation [GO:0009953]; male meiosis cytokinesis [GO:0007112]; male meiotic nuclear division [GO:0007140]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of neuron death [GO:1901215]; oocyte development [GO:0048599]; oogenesis [GO:0048477]; positive regulation of translation [GO:0045727]; regulation of compound eye photoreceptor development [GO:0045314]; spermatid nucleus differentiation [GO:0007289]; spermatogenesis [GO:0007283] GO:0000398; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0007112; GO:0007140; GO:0007268; GO:0007283; GO:0007289; GO:0008143; GO:0008266; GO:0009953; GO:0010494; GO:0045202; GO:0045314; GO:0045727; GO:0048477; GO:0048599; GO:0071011; GO:0071013; GO:1901215; GO:1990904 16172 FUN_032714 3932 2337 1408 3534 1391 ptg000023l:35166827-35175770 P20965 3.66e-67 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 16173 FUN_032714 3932 2337 1408 3534 1391 ptg000023l:35166827-35175770 P20965 3.66e-67 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 16174 FUN_032714 3932 2337 1408 3534 1391 ptg000023l:35166827-35175770 P20965 1.26e-24 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 16175 FUN_032714 3932 2337 1408 3534 1391 ptg000023l:35166827-35175770 P20965 2.06e-24 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 16176 FUN_032717 0 0 0 28 0 NA NA NA NA NA NA NA 16177 FUN_032716 0 0 0 0 8 NA NA NA NA NA NA NA 16178 FUN_032718 0 28 0 14 28 NA NA NA NA NA NA NA 16179 FUN_004192 35 51 96 81 33 NA NA NA NA NA NA NA 16180 FUN_004193 514 707 40 190 0 NA NA NA NA NA NA NA 16181 FUN_004190 1 0 14 4 103 NA NA NA NA NA NA NA 16182 FUN_004196 523 222 265 441 507 NA NA NA NA NA NA NA 16183 FUN_004197 578 1124 233 767 516 NA NA NA NA NA NA NA 16184 FUN_004194 678 337 270 620 231 NA NA NA NA NA NA NA 16185 FUN_004195 270 163 135 129 79 NA NA NA NA NA NA NA 16186 FUN_004198 335 517 125 538 362 ntLink_8:20711739-20713334 A2VDD2 9.58e-47 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 16187 FUN_004199 74 46 22 0 18 NA NA NA NA NA NA NA 16188 FUN_034719 1075 528 179 959 769 NA NA NA NA NA NA NA 16189 FUN_034718 1058 964 725 949 872 NA NA NA NA NA NA NA 16190 FUN_034713 617 183 243 382 584 NA NA NA NA NA NA NA 16191 FUN_034712 3089 1821 1456 3524 3312 NA NA NA NA NA NA NA 16192 FUN_034711 0 3 0 31 40 NA NA NA NA NA NA NA 16193 FUN_034710 13 11 0 0 25 NA NA NA NA NA NA NA 16194 FUN_034717 903 694 682 506 309 ptg000024l:10690333-10694469 Q91754 1.92e-59 Glucokinase regulatory protein (GKRP) (Glucokinase regulator) Xenopus laevis (African clawed frog) carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132] GO:0005654; GO:0005737; GO:0005739; GO:0005975; GO:0033132; GO:0070095; GO:1901135 16195 FUN_034717 903 694 682 506 309 ptg000024l:10690333-10694469 Q91754 2.12e-50 Glucokinase regulatory protein (GKRP) (Glucokinase regulator) Xenopus laevis (African clawed frog) carbohydrate derivative metabolic process [GO:1901135]; carbohydrate metabolic process [GO:0005975]; negative regulation of glucokinase activity [GO:0033132] GO:0005654; GO:0005737; GO:0005739; GO:0005975; GO:0033132; GO:0070095; GO:1901135 16196 FUN_034715 10189 17352 6288 11899 7449 NA NA NA NA NA NA NA 16197 FUN_034714 0 14 0 29 28 NA NA NA NA NA NA NA 16198 FUN_001119 152 142 91 142 162 NA NA NA NA NA NA NA 16199 FUN_001118 19622 43556 19235 18239 12830 NA NA NA NA NA NA NA 16200 FUN_001111 55 35 26 0 72 NA NA NA NA NA NA NA 16201 FUN_001110 2213 456 812 1533 1054 ntLink_6:8665284-8679029 Q28293 6.34e-82 Potassium voltage-gated channel subfamily A member 2 (CSMK1) (Voltage-gated potassium channel subunit Kv1.2) Canis lupus familiaris (Dog) (Canis familiaris) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0016020; GO:0019228; GO:0019233; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043204; GO:0043679; GO:0044224; GO:0051260; GO:0071805 16202 FUN_001113 135 80 132 242 192 NA NA NA NA NA NA NA 16203 FUN_001112 0 120 57 27 155 NA NA NA NA NA NA NA 16204 FUN_001115 2525 3859 2084 2534 1771 NA NA NA NA NA NA NA 16205 FUN_001114 2820 1903 1098 1590 886 ntLink_6:8711625-8715698 Q99MH5 8.46e-22 Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (Rsph23) (nm23-M5) Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; CTP biosynthetic process [GO:0006241]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; GTP biosynthetic process [GO:0006183]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; nucleoside diphosphate phosphorylation [GO:0006165]; response to reactive oxygen species [GO:0000302]; spermatid development [GO:0007286]; UTP biosynthetic process [GO:0006228]; ventricular system development [GO:0021591] GO:0000302; GO:0003341; GO:0003351; GO:0004550; GO:0005576; GO:0005929; GO:0006165; GO:0006183; GO:0006228; GO:0006241; GO:0007286; GO:0021591; GO:0036126; GO:0051649; GO:0060271; GO:1902176 16206 FUN_001117 109 363 225 800 276 NA NA NA NA NA NA NA 16207 FUN_001116 3299 1274 1702 2900 1576 NA NA NA NA NA NA NA 16208 FUN_011749 2862 3036 1409 1866 1883 NA NA NA NA NA NA NA 16209 FUN_011748 512 638 495 308 760 NA NA NA NA NA NA NA 16210 FUN_011745 1545 1216 659 843 417 NA NA NA NA NA NA NA 16211 FUN_011744 10 0 0 0 0 NA NA NA NA NA NA NA 16212 FUN_011747 240 113 248 206 246 NA NA NA NA NA NA NA 16213 FUN_011746 1319 1039 753 1358 1298 ptg000008l:860203-871791 A7SD85 3.44e-35 Cell division cycle 5-related protein (Cdc5-like protein) Nematostella vectensis (Starlet sea anemone) cell cycle [GO:0007049]; DNA repair [GO:0006281]; mRNA splicing, via spliceosome [GO:0000398]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000398; GO:0000974; GO:0000977; GO:0000981; GO:0003723; GO:0005681; GO:0005737; GO:0006281; GO:0006357; GO:0007049 16214 FUN_011741 2264 1038 752 1569 1518 NA NA NA NA NA NA NA 16215 FUN_011740 9239 12529 5980 7579 5509 NA NA NA NA NA NA NA 16216 FUN_011743 158 133 98 101 172 ptg000008l:829441-833827 B3DM66 5.2e-21 G-protein coupled receptor 161 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007189; GO:0055037; GO:0060170; GO:1901621 16217 FUN_011742 404 215 297 425 415 NA NA NA NA NA NA NA 16218 FUN_000444 0 0 9 0 0 NA NA NA NA NA NA NA 16219 FUN_000445 788 1770 1542 1644 450 NA NA NA NA NA NA NA 16220 FUN_000446 588 896 916 1107 261 NA NA NA NA NA NA NA 16221 FUN_000447 1468 1592 1443 2109 624 NA NA NA NA NA NA NA 16222 FUN_000440 4898 1665 2514 4758 3016 ntLink_6:3033453-3073750 E9Q4Z2 4.71e-25 Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta) Mus musculus (Mouse) acetyl-CoA metabolic process [GO:0006084]; energy homeostasis [GO:0097009]; fatty acid biosynthetic process [GO:0006633]; malonyl-CoA biosynthetic process [GO:2001295]; negative regulation of catalytic activity [GO:0043086]; negative regulation of fatty acid beta-oxidation [GO:0031999]; negative regulation of fatty acid oxidation [GO:0046322]; negative regulation of gene expression [GO:0010629]; negative regulation of lipid catabolic process [GO:0050995]; positive regulation of heart growth [GO:0060421]; positive regulation of lipid storage [GO:0010884]; protein homotetramerization [GO:0051289]; regulation of glucose metabolic process [GO:0010906]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410] GO:0003989; GO:0005524; GO:0005634; GO:0005739; GO:0006084; GO:0006633; GO:0009374; GO:0009410; GO:0010629; GO:0010884; GO:0010906; GO:0014070; GO:0031667; GO:0031999; GO:0042802; GO:0043086; GO:0046322; GO:0046872; GO:0050995; GO:0051289; GO:0060421; GO:0097009; GO:2001295 16223 FUN_000441 362 354 261 444 489 NA NA NA NA NA NA NA 16224 FUN_000442 120 0 28 57 91 NA NA NA NA NA NA NA 16225 FUN_000443 62 64 6 0 15 NA NA NA NA NA NA NA 16226 FUN_000448 978 448 201 788 717 NA NA NA NA NA NA NA 16227 FUN_000449 688 460 315 412 466 NA NA NA NA NA NA NA 16228 FUN_029379 364 324 355 407 253 NA NA NA NA NA NA NA 16229 FUN_000998 795 1510 448 2993 899 NA NA NA NA NA NA NA 16230 FUN_000999 74 75 43 41 30 NA NA NA NA NA NA NA 16231 FUN_000996 390 1506 1388 2018 717 NA NA NA NA NA NA NA 16232 FUN_000997 136 66 73 108 104 NA NA NA NA NA NA NA 16233 FUN_029371 1 0 0 4 6 NA NA NA NA NA NA NA 16234 FUN_000995 75 105 121 75 17 NA NA NA NA NA NA NA 16235 FUN_000992 5918 3917 3027 5033 3324 ntLink_6:6963176-6968999 P29992 3.99e-31 Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha) Homo sapiens (Human) action potential [GO:0001508]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to pH [GO:0071467]; cranial skeletal system development [GO:1904888]; developmental pigmentation [GO:0048066]; endothelin receptor signaling pathway [GO:0086100]; entrainment of circadian clock [GO:0009649]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; heart development [GO:0007507]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; multicellular organism aging [GO:0010259]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; phototransduction, visible light [GO:0007603]; positive regulation of insulin secretion [GO:0032024]; regulation of blood pressure [GO:0008217]; regulation of melanocyte differentiation [GO:0045634]; signal transduction [GO:0007165]; skeletal system development [GO:0001501] GO:0001501; GO:0001508; GO:0001664; GO:0001750; GO:0003924; GO:0003925; GO:0005246; GO:0005525; GO:0005737; GO:0005765; GO:0005834; GO:0005886; GO:0007165; GO:0007188; GO:0007207; GO:0007213; GO:0007507; GO:0007603; GO:0008217; GO:0009649; GO:0010259; GO:0016004; GO:0031683; GO:0032024; GO:0045202; GO:0045634; GO:0046872; GO:0048066; GO:0060158; GO:0070062; GO:0071467; GO:0086100; GO:0099103; GO:0099105; GO:0099107; GO:1904888; GO:1990806 16236 FUN_000992 5918 3917 3027 5033 3324 ntLink_6:6963176-6968999 P29992 2.55e-22 Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11) (Guanine nucleotide-binding protein G(y) subunit alpha) Homo sapiens (Human) action potential [GO:0001508]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cellular response to pH [GO:0071467]; cranial skeletal system development [GO:1904888]; developmental pigmentation [GO:0048066]; endothelin receptor signaling pathway [GO:0086100]; entrainment of circadian clock [GO:0009649]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; heart development [GO:0007507]; ion channel modulating, G protein-coupled receptor signaling pathway [GO:0099105]; ligand-gated ion channel signaling pathway [GO:1990806]; multicellular organism aging [GO:0010259]; phospholipase C-activating dopamine receptor signaling pathway [GO:0060158]; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway [GO:0007207]; phototransduction, visible light [GO:0007603]; positive regulation of insulin secretion [GO:0032024]; regulation of blood pressure [GO:0008217]; regulation of melanocyte differentiation [GO:0045634]; signal transduction [GO:0007165]; skeletal system development [GO:0001501] GO:0001501; GO:0001508; GO:0001664; GO:0001750; GO:0003924; GO:0003925; GO:0005246; GO:0005525; GO:0005737; GO:0005765; GO:0005834; GO:0005886; GO:0007165; GO:0007188; GO:0007207; GO:0007213; GO:0007507; GO:0007603; GO:0008217; GO:0009649; GO:0010259; GO:0016004; GO:0031683; GO:0032024; GO:0045202; GO:0045634; GO:0046872; GO:0048066; GO:0060158; GO:0070062; GO:0071467; GO:0086100; GO:0099103; GO:0099105; GO:0099107; GO:1904888; GO:1990806 16237 FUN_029376 1834 314 169 1196 288 NA NA NA NA NA NA NA 16238 FUN_000990 6972 9634 5650 5599 3900 NA NA NA NA NA NA NA 16239 FUN_000991 0 0 7 20 31 NA NA NA NA NA NA NA 16240 FUN_022776 1058 1319 436 724 1292 NA NA NA NA NA NA NA 16241 FUN_026231 1291 80 120 37 201 ptg000020l:6490181-6504386 Q4UMH6 1.13e-44 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 16242 FUN_026231 1291 80 120 37 201 ptg000020l:6490181-6504386 Q4UMH6 4.68e-43 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 16243 FUN_026231 1291 80 120 37 201 ptg000020l:6490181-6504386 Q4UMH6 6.79e-40 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 16244 FUN_026231 1291 80 120 37 201 ptg000020l:6490181-6504386 Q4UMH6 7.66e-39 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 16245 FUN_026231 1291 80 120 37 201 ptg000020l:6490181-6504386 Q4UMH6 2.52e-38 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 16246 FUN_022304 77 22 0 2 2 NA NA NA NA NA NA NA 16247 FUN_043489 1234 968 554 855 426 NA NA NA NA NA NA NA 16248 FUN_043488 310 245 157 417 327 NA NA NA NA NA NA NA 16249 FUN_043481 1231 1178 1146 1624 1929 NA NA NA NA NA NA NA 16250 FUN_043480 277 99 183 298 104 NA NA NA NA NA NA NA 16251 FUN_043483 3423 12545 4640 10267 3322 NA NA NA NA NA NA NA 16252 FUN_043482 941 433 313 365 588 NA NA NA NA NA NA NA 16253 FUN_043485 105150 89238 54918 100700 14710 NA NA NA NA NA NA NA 16254 FUN_043484 1470 858 508 1752 440 ptg000047l:9183906-9185001 Q861W0 1.25e-27 NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1) Pan troglodytes (Chimpanzee) cellular response to lipopolysaccharide [GO:0071222]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of lipopolysaccharide-mediated signaling pathway [GO:0031665]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; negative regulation of tumor necrosis factor production [GO:0032720] GO:0005634; GO:0007249; GO:0031665; GO:0032088; GO:0032720; GO:0034122; GO:0071222 16255 FUN_043487 267 105 73 128 274 NA NA NA NA NA NA NA 16256 FUN_043486 651 389 255 464 1267 NA NA NA NA NA NA NA 16257 FUN_012502 230 50 157 115 95 NA NA NA NA NA NA NA 16258 FUN_012503 4202 135 2059 2128 1866 NA NA NA NA NA NA NA 16259 FUN_012500 729 226 525 244 332 NA NA NA NA NA NA NA 16260 FUN_012501 1072 461 536 505 445 NA NA NA NA NA NA NA 16261 FUN_012506 3272 403 1885 1266 1115 NA NA NA NA NA NA NA 16262 FUN_012507 1225 614 538 612 418 NA NA NA NA NA NA NA 16263 FUN_012504 73 7 48 15 23 NA NA NA NA NA NA NA 16264 FUN_012505 4062 109 2062 2026 1625 NA NA NA NA NA NA NA 16265 FUN_012508 289 101 210 132 116 NA NA NA NA NA NA NA 16266 FUN_012509 107 25 73 85 44 NA NA NA NA NA NA NA 16267 FUN_016212 0 0 0 0 49 NA NA NA NA NA NA NA 16268 FUN_016213 110 139 174 107 213 NA NA NA NA NA NA NA 16269 FUN_016210 0 12 0 0 0 NA NA NA NA NA NA NA 16270 FUN_016211 13 0 5 2 297 ptg000011l:421880-422411 O35516 5.82e-33 Neurogenic locus notch homolog protein 2 (Notch 2) (Motch B) [Cleaved into: Notch 2 extracellular truncation; Notch 2 intracellular domain] Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; atrial septum morphogenesis [GO:0060413]; BMP signaling pathway [GO:0030509]; bone remodeling [GO:0046849]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to tumor cell [GO:0071228]; central nervous system development [GO:0007417]; cholangiocyte proliferation [GO:1990705]; ciliary body morphogenesis [GO:0061073]; defense response to bacterium [GO:0042742]; determination of left/right symmetry [GO:0007368]; embryonic limb morphogenesis [GO:0030326]; glomerular capillary formation [GO:0072104]; heart looping [GO:0001947]; hepatocyte proliferation [GO:0072574]; humoral immune response [GO:0006959]; in utero embryonic development [GO:0001701]; inflammatory response to antigenic stimulus [GO:0002437]; intrahepatic bile duct development [GO:0035622]; left/right axis specification [GO:0070986]; liver development [GO:0001889]; liver morphogenesis [GO:0072576]; marginal zone B cell differentiation [GO:0002315]; morphogenesis of an epithelial sheet [GO:0002011]; multicellular organism growth [GO:0035264]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of gene expression [GO:0010629]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; placenta blood vessel development [GO:0060674]; placenta development [GO:0001890]; podocyte development [GO:0072015]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of keratinocyte proliferation [GO:0010838]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of Ras protein signal transduction [GO:0046579]; proximal tubule development [GO:0072014]; pulmonary valve morphogenesis [GO:0003184]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of osteoclast development [GO:2001204]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; wound healing [GO:0042060] GO:0000122; GO:0001501; GO:0001701; GO:0001709; GO:0001889; GO:0001890; GO:0001947; GO:0002011; GO:0002315; GO:0002437; GO:0003184; GO:0005509; GO:0005576; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0005929; GO:0006357; GO:0006915; GO:0006959; GO:0007219; GO:0007368; GO:0007417; GO:0008283; GO:0008284; GO:0009887; GO:0009986; GO:0010629; GO:0010838; GO:0019899; GO:0030326; GO:0030509; GO:0030513; GO:0031012; GO:0035264; GO:0035622; GO:0038023; GO:0042060; GO:0042742; GO:0043011; GO:0043065; GO:0043235; GO:0045672; GO:0046579; GO:0046849; GO:0051059; GO:0060413; GO:0060674; GO:0061073; GO:0070374; GO:0070986; GO:0071228; GO:0072014; GO:0072015; GO:0072104; GO:0072574; GO:0072576; GO:1990705; GO:2000249; GO:2001204 16271 FUN_016216 49 58 31 100 79 NA NA NA NA NA NA NA 16272 FUN_016217 127 49 65 47 144 NA NA NA NA NA NA NA 16273 FUN_016215 0 0 0 34 0 NA NA NA NA NA NA NA 16274 FUN_016218 2 1 10 4 11 NA NA NA NA NA NA NA 16275 FUN_016219 77 84 56 207 167 NA NA NA NA NA NA NA 16276 FUN_013457 735 367 359 811 119 ptg000008l:22789987-22799429 Q99570 3.81e-45 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16277 FUN_013457 735 367 359 811 119 ptg000008l:22789987-22799429 Q99570 5e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16278 FUN_013456 47 14 35 60 10 ptg000008l:22788809-22789217 P0C0R5 1.58e-27 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16279 FUN_013455 142 164 75 84 106 NA NA NA NA NA NA NA 16280 FUN_013454 992 1213 634 503 98 ptg000008l:22757144-22766102 Q7RTR2 2.21e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16281 FUN_013454 992 1213 634 503 98 ptg000008l:22757144-22766102 Q7RTR2 2.07e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16282 FUN_013454 992 1213 634 503 98 ptg000008l:22757144-22766102 Q7RTR2 3.48e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16283 FUN_013454 992 1213 634 503 98 ptg000008l:22757144-22766102 Q7RTR2 2.5e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16284 FUN_013451 404 526 236 98 59 ptg000008l:22725358-22733933 Q7RTR2 1.28e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16285 FUN_013451 404 526 236 98 59 ptg000008l:22725358-22733933 Q7RTR2 3.06e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16286 FUN_013451 404 526 236 98 59 ptg000008l:22725358-22733933 Q7RTR2 2.9e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16287 FUN_013450 203 515 173 341 185 ptg000008l:22692803-22699999 Q7RTR2 1.73e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16288 FUN_013450 203 515 173 341 185 ptg000008l:22692803-22699999 Q7RTR2 1.09e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16289 FUN_013450 203 515 173 341 185 ptg000008l:22692803-22699999 Q7RTR2 3.4e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16290 FUN_013459 0 0 16 0 0 ptg000008l:22832408-22840214 P21328 5.65e-34 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 16291 FUN_013458 1235 425 693 762 273 ptg000008l:22810033-22817494 Q7RTR2 2.35e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16292 FUN_013458 1235 425 693 762 273 ptg000008l:22810033-22817494 Q7RTR2 1.07e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16293 FUN_013458 1235 425 693 762 273 ptg000008l:22810033-22817494 Q7RTR2 3.11e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16294 FUN_013458 1235 425 693 762 273 ptg000008l:22810033-22817494 Q7RTR2 8.14e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16295 FUN_010904 1 0 2 2 22 NA NA NA NA NA NA NA 16296 FUN_010900 63736 72772 38979 50578 30392 ptg000007l:4076238-4077141 R1CW23 2.38e-119 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 16297 FUN_043736 0 0 44 0 14 NA NA NA NA NA NA NA 16298 FUN_043734 0 0 19 0 0 NA NA NA NA NA NA NA 16299 FUN_010908 24610 21116 15369 23707 3549 ptg000007l:4124166-4125003 R1CW23 1.38e-112 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 16300 FUN_010909 40747 19959 17639 19038 20464 ptg000007l:4134003-4134840 R1CW23 2.96e-108 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 16301 FUN_042284 150 52 97 79 2 NA NA NA NA NA NA NA 16302 FUN_042285 31 25 0 29 0 NA NA NA NA NA NA NA 16303 FUN_023038 1099 980 464 1055 859 NA NA NA NA NA NA NA 16304 FUN_023039 2087 1818 981 1658 1394 ptg000017l:2919699-2924109 Q5RCQ6 3.77e-21 ADP-ribosylation factor-like protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; kidney development [GO:0001822]; mitotic cytokinesis [GO:0000281]; photoreceptor cell development [GO:0042461]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] GO:0000139; GO:0000281; GO:0001822; GO:0003924; GO:0005525; GO:0005634; GO:0005794; GO:0005813; GO:0005876; GO:0005881; GO:0005929; GO:0006893; GO:0007264; GO:0008017; GO:0015031; GO:0019003; GO:0030496; GO:0032391; GO:0042461; GO:0060271; GO:1903441 16305 FUN_023039 2087 1818 981 1658 1394 ptg000017l:2919699-2924109 Q5RCQ6 3.77e-21 ADP-ribosylation factor-like protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cilium assembly [GO:0060271]; Golgi to plasma membrane transport [GO:0006893]; kidney development [GO:0001822]; mitotic cytokinesis [GO:0000281]; photoreceptor cell development [GO:0042461]; protein localization to ciliary membrane [GO:1903441]; protein transport [GO:0015031]; small GTPase mediated signal transduction [GO:0007264] GO:0000139; GO:0000281; GO:0001822; GO:0003924; GO:0005525; GO:0005634; GO:0005794; GO:0005813; GO:0005876; GO:0005881; GO:0005929; GO:0006893; GO:0007264; GO:0008017; GO:0015031; GO:0019003; GO:0030496; GO:0032391; GO:0042461; GO:0060271; GO:1903441 16306 FUN_023036 19 52 0 6 29 NA NA NA NA NA NA NA 16307 FUN_023037 544 359 382 667 938 NA NA NA NA NA NA NA 16308 FUN_023034 11 20 2 0 0 ptg000017l:2908178-2908541 Q9PSW9 1.73e-60 Histone H2B 8 (H2B VIII) Gallus gallus (Chicken) nucleosome assembly [GO:0006334] GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 16309 FUN_023035 103 13 0 0 0 ptg000017l:2908885-2910209 P35061 2.34e-60 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16310 FUN_023030 16 7 9 0 22 NA NA NA NA NA NA NA 16311 FUN_023031 184 168 53 206 14 NA NA NA NA NA NA NA 16312 FUN_036821 35 3145 165 2303 0 ptg000026l:2287994-2345814 B8V7S0 1.31e-95 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 16313 FUN_036821 35 3145 165 2303 0 ptg000026l:2287994-2345814 B8V7S0 3.79e-21 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 16314 FUN_036827 870 369 329 500 828 NA NA NA NA NA NA NA 16315 FUN_036826 5600 4007 2320 4055 3544 NA NA NA NA NA NA NA 16316 FUN_036829 2846 2387 1937 2859 2765 NA NA NA NA NA NA NA 16317 FUN_036828 33 2 27 0 274 NA NA NA NA NA NA NA 16318 FUN_008857 58 573 554 580 70 NA NA NA NA NA NA NA 16319 FUN_008856 0 0 0 7 0 NA NA NA NA NA NA NA 16320 FUN_008855 22 26 39 60 42 NA NA NA NA NA NA NA 16321 FUN_008852 432 326 129 161 333 NA NA NA NA NA NA NA 16322 FUN_008851 47 98 75 22 0 NA NA NA NA NA NA NA 16323 FUN_008850 811 404 0 194 220 NA NA NA NA NA NA NA 16324 FUN_008859 14 33 92 38 8 NA NA NA NA NA NA NA 16325 FUN_008858 104 76 74 194 54 NA NA NA NA NA NA NA 16326 FUN_041393 302 590 412 3835 2173 NA NA NA NA NA NA NA 16327 FUN_041392 119 225 115 1614 728 NA NA NA NA NA NA NA 16328 FUN_023783 0 0 0 0 7 NA NA NA NA NA NA NA 16329 FUN_023784 1 0 22 0 5 NA NA NA NA NA NA NA 16330 FUN_041396 45 15 35 24 8 NA NA NA NA NA NA NA 16331 FUN_041394 0 0 0 9 0 NA NA NA NA NA NA NA 16332 FUN_041399 26 5 0 0 6 NA NA NA NA NA NA NA 16333 FUN_041645 5232 2086 1918 7659 4850 ptg000035l:6158427-6163755 Q6Q4G4 7.68e-78 Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE) Theromyzon tessulatum (Duck leech) proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0006508; GO:0008237; GO:0008241; GO:0016020; GO:0046872 16334 FUN_041645 5232 2086 1918 7659 4850 ptg000035l:6158427-6163755 Q6Q4G4 3.78e-25 Angiotensin-converting enzyme (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (TtACE) Theromyzon tessulatum (Duck leech) proteolysis [GO:0006508] GO:0004180; GO:0005615; GO:0006508; GO:0008237; GO:0008241; GO:0016020; GO:0046872 16335 FUN_041644 639 392 286 782 659 ptg000035l:6151397-6156909 Q58DD0 1.15e-52 Angiotensin-converting enzyme 2 (EC 3.4.17.23) (ACE-related carboxypeptidase) (EC 3.4.17.-) [Cleaved into: Processed angiotensin-converting enzyme 2] Bos taurus (Bovine) proteolysis [GO:0006508] GO:0001618; GO:0004180; GO:0005615; GO:0005737; GO:0005886; GO:0005929; GO:0006508; GO:0008237; GO:0008241; GO:0009986; GO:0016324; GO:0046872 16336 FUN_041647 1223 869 539 1316 1155 ptg000035l:6169430-6180050 A7RR04 9.05e-22 Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) Nematostella vectensis (Starlet sea anemone) mitochondrial translational elongation [GO:0070125] GO:0003746; GO:0003924; GO:0005525; GO:0005739; GO:0070125 16337 FUN_041647 1223 869 539 1316 1155 ptg000035l:6169430-6180050 A7RR04 9.05e-22 Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) Nematostella vectensis (Starlet sea anemone) mitochondrial translational elongation [GO:0070125] GO:0003746; GO:0003924; GO:0005525; GO:0005739; GO:0070125 16338 FUN_041647 1223 869 539 1316 1155 ptg000035l:6169430-6180050 A7RR04 9.05e-22 Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) Nematostella vectensis (Starlet sea anemone) mitochondrial translational elongation [GO:0070125] GO:0003746; GO:0003924; GO:0005525; GO:0005739; GO:0070125 16339 FUN_041646 0 0 0 12 20 NA NA NA NA NA NA NA 16340 FUN_041641 628 392 265 386 172 NA NA NA NA NA NA NA 16341 FUN_041640 7189 3823 2544 3961 4412 NA NA NA NA NA NA NA 16342 FUN_041643 439 349 255 343 430 NA NA NA NA NA NA NA 16343 FUN_041642 3036 1838 1278 2112 1779 ptg000035l:6136983-6146817 Q3TCH7 1.03e-28 Cullin-4A (CUL-4A) Mus musculus (Mouse) cell population proliferation [GO:0008283]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; hemopoiesis [GO:0030097]; in utero embryonic development [GO:0001701]; negative regulation of granulocyte differentiation [GO:0030853]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of protein catabolic process [GO:0045732]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; regulation of nucleotide-excision repair [GO:2000819]; regulation of protein metabolic process [GO:0051246]; rhythmic process [GO:0048511]; ribosome biogenesis [GO:0042254]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; somatic stem cell population maintenance [GO:0035019]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001701; GO:0005634; GO:0006281; GO:0006511; GO:0006974; GO:0008283; GO:0008284; GO:0016567; GO:0030097; GO:0030674; GO:0030853; GO:0031146; GO:0031461; GO:0031464; GO:0031625; GO:0034644; GO:0035019; GO:0042254; GO:0043161; GO:0045732; GO:0048511; GO:0051246; GO:0080008; GO:1900087; GO:2000001; GO:2000819 16344 FUN_023821 0 0 0 1 20 NA NA NA NA NA NA NA 16345 FUN_041649 379 315 164 469 696 NA NA NA NA NA NA NA 16346 FUN_009103 0 0 17 0 0 NA NA NA NA NA NA NA 16347 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 4.5e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16348 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 1.8e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16349 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 1.54e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16350 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 2.87e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16351 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 1.13e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16352 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 1.68e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16353 FUN_009100 21 100 183 18 15 ptg000004l:2728871-2735160 Q96AY4 5.98e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16354 FUN_009101 384 648 329 7 16 NA NA NA NA NA NA NA 16355 FUN_009107 49 67 17 53 48 ptg000004l:2764582-2769156 Q96AY4 3.43e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16356 FUN_009107 49 67 17 53 48 ptg000004l:2764582-2769156 Q96AY4 1.42e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16357 FUN_009107 49 67 17 53 48 ptg000004l:2764582-2769156 Q96AY4 1.78e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16358 FUN_009104 0 0 4 2 8 NA NA NA NA NA NA NA 16359 FUN_022788 0 14 0 1 27 NA NA NA NA NA NA NA 16360 FUN_022787 220 561 125 618 295 NA NA NA NA NA NA NA 16361 FUN_022780 6466 4522 2947 3814 5150 ptg000016l:12895570-12900267 Q8K3P4 9.42e-42 RNA-binding protein Musashi homolog 1 (Musashi-1) Rattus norvegicus (Rat) central nervous system development [GO:0007417]; epithelial cell differentiation [GO:0030855]; regulation of translation [GO:0006417]; response to hormone [GO:0009725] GO:0003723; GO:0003727; GO:0003729; GO:0005634; GO:0005737; GO:0005844; GO:0006417; GO:0007417; GO:0008266; GO:0009725; GO:0030855; GO:0042802 16362 FUN_030077 0 37 0 2 38 NA NA NA NA NA NA NA 16363 FUN_014101 4 4 8 35 18 ptg000008l:31641427-31642465 Q9EQD2 1.34e-26 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 16364 FUN_014102 1381 988 784 1290 1398 NA NA NA NA NA NA NA 16365 FUN_014103 2284 1172 823 1581 1673 ptg000008l:31660854-31706637 Q6P5E4 3.37e-23 UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0003980; GO:0005783; GO:0005788; GO:0005793; GO:0018279; GO:0032991; GO:0051082; GO:0071712 16366 FUN_014104 21 0 0 0 34 NA NA NA NA NA NA NA 16367 FUN_014105 0 0 18 0 0 NA NA NA NA NA NA NA 16368 FUN_014108 52 0 77 18 191 NA NA NA NA NA NA NA 16369 FUN_014109 13 0 0 0 9 NA NA NA NA NA NA NA 16370 FUN_044345 0 0 0 8 0 NA NA NA NA NA NA NA 16371 FUN_025067 0 0 0 0 11 NA NA NA NA NA NA NA 16372 FUN_025066 18 15 27 8 14 NA NA NA NA NA NA NA 16373 FUN_025065 0 32 42 9 88 NA NA NA NA NA NA NA 16374 FUN_025064 32 33 39 5 8 NA NA NA NA NA NA NA 16375 FUN_025063 89 142 62 168 116 NA NA NA NA NA NA NA 16376 FUN_025062 119 188 399 900 480 ptg000018l:13441404-13442292 Q6DHN0 7.86e-25 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 16377 FUN_025068 44 0 38 0 102 NA NA NA NA NA NA NA 16378 FUN_024334 3944 2916 1937 2483 1621 NA NA NA NA NA NA NA 16379 FUN_024335 4510 5079 4948 4065 2035 NA NA NA NA NA NA NA 16380 FUN_024336 926 503 698 1009 1187 NA NA NA NA NA NA NA 16381 FUN_024337 882 558 806 472 427 ptg000018l:5037810-5040544 O14059 2.15e-35 Probable histidinol-phosphatase (HolPase) (EC 3.1.3.15) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) histidine biosynthetic process [GO:0000105] GO:0000105; GO:0004401; GO:0005634; GO:0005829 16382 FUN_024330 6802 2899 1850 4138 2161 ptg000018l:4988974-4990687 F8W2M8 0 Tripeptidyl-peptidase 1 (TPP-1) (EC 3.4.14.9) (Tripeptidyl aminopeptidase) (Tripeptidyl-peptidase I) (TPP-I) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; locomotory behavior [GO:0007626]; neurogenesis [GO:0022008]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005764; GO:0006508; GO:0007417; GO:0007626; GO:0008240; GO:0022008; GO:0046872 16383 FUN_024331 1366 1124 534 1365 1260 NA NA NA NA NA NA NA 16384 FUN_024332 47501 43606 30300 39183 30317 ptg000018l:4995571-4999284 A7S3J7 6.79e-31 40S ribosomal protein S3a Nematostella vectensis (Starlet sea anemone) translation [GO:0006412] GO:0003735; GO:0005829; GO:0006412; GO:0022627 16385 FUN_024332 47501 43606 30300 39183 30317 ptg000018l:4995571-4999284 A7S3J7 6.07e-28 40S ribosomal protein S3a Nematostella vectensis (Starlet sea anemone) translation [GO:0006412] GO:0003735; GO:0005829; GO:0006412; GO:0022627 16386 FUN_024333 1505 461 884 934 605 ptg000018l:5001942-5009749 Q8BFR4 1.17e-33 N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S) Mus musculus (Mouse) keratan sulfate catabolic process [GO:0042340] GO:0005539; GO:0005764; GO:0008449; GO:0008484; GO:0042340; GO:0043199; GO:0046872 16387 FUN_024338 4139 3226 2174 4245 2831 NA NA NA NA NA NA NA 16388 FUN_024339 53 20 53 101 68 ptg000018l:5062605-5066348 Q96H96 8.29e-22 4-hydroxybenzoate polyprenyltransferase, mitochondrial (4-HB polyprenyltransferase) (EC 2.5.1.39) (4-hydroxybenzoate decaprenyltransferase) (COQ2 homolog) (hCOQ2) (Para-hydroxybenzoate--polyprenyltransferase) (PHB:PPT) (PHB:polyprenyltransferase) Homo sapiens (Human) glycerol metabolic process [GO:0006071]; isoprenoid biosynthetic process [GO:0008299]; ubiquinone biosynthetic process [GO:0006744] GO:0002083; GO:0004659; GO:0005743; GO:0006071; GO:0006744; GO:0008299; GO:0008412; GO:0016765; GO:0047293 16389 FUN_040118 5000 3761 5561 12458 6103 ptg000031l:4409714-4435371 P27590 2.55e-21 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 16390 FUN_040112 19 2 72 30 0 NA NA NA NA NA NA NA 16391 FUN_040113 288 406 194 262 278 NA NA NA NA NA NA NA 16392 FUN_040110 2691 2280 872 2301 1137 NA NA NA NA NA NA NA 16393 FUN_040111 2237 1358 780 1034 879 NA NA NA NA NA NA NA 16394 FUN_040116 1531 807 266 734 832 ptg000031l:4368735-4375156 Q12933 4.6e-62 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 16395 FUN_040117 175 57 122 278 115 NA NA NA NA NA NA NA 16396 FUN_040114 217 292 167 214 468 NA NA NA NA NA NA NA 16397 FUN_043319 1778 1125 862 2144 1282 ptg000047l:6992893-7018182 Q9CYL5 1.55e-32 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 16398 FUN_043319 1778 1125 862 2144 1282 ptg000047l:6992893-7018182 Q9CYL5 3.14e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 16399 FUN_022424 2480 1795 1311 2433 2174 ptg000016l:8925419-8939288 Q5I0G4 2.42e-21 Glycine--tRNA ligase (EC 6.1.1.14) (Diadenosine tetraphosphate synthetase) (Ap4A synthetase) (EC 2.7.7.-) (Glycyl-tRNA synthetase) (GlyRS) (Glycyl-tRNA synthetase 1) Rattus norvegicus (Rat) diadenosine tetraphosphate biosynthetic process [GO:0015966]; glycyl-tRNA aminoacylation [GO:0006426]; tRNA aminoacylation for protein translation [GO:0006418] GO:0004081; GO:0004820; GO:0005524; GO:0005739; GO:0005829; GO:0006418; GO:0006426; GO:0015966; GO:0016740; GO:0030141; GO:0030424; GO:0042802; GO:0046983; GO:0070062 16400 FUN_007116 2316 1350 1067 1719 1116 NA NA NA NA NA NA NA 16401 FUN_015271 600 1400 1014 1181 2089 NA NA NA NA NA NA NA 16402 FUN_015270 984 617 678 1124 1573 NA NA NA NA NA NA NA 16403 FUN_015273 4819 8790 2626 4355 2287 NA NA NA NA NA NA NA 16404 FUN_015272 2118 1606 661 1097 709 ptg000009l:8137616-8147705 Q5ZIA0 3.72e-27 RNA N6-adenosine-methyltransferase METTL16 (Methyltransferase 10 domain-containing protein) (Methyltransferase-like protein 16) (N6-adenosine-methyltransferase METTL16) (EC 2.1.1.348) (U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase) (EC 2.1.1.346) Gallus gallus (Chicken) mRNA catabolic process [GO:0006402]; mRNA destabilization [GO:0061157]; mRNA methylation [GO:0080009]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of mRNA splicing, via spliceosome [GO:0048024]; rRNA base methylation [GO:0070475]; S-adenosylmethionine biosynthetic process [GO:0006556]; snRNA (adenine-N6)-methylation [GO:0120049] GO:0001734; GO:0003723; GO:0005634; GO:0005737; GO:0006402; GO:0006556; GO:0010608; GO:0030629; GO:0035613; GO:0048024; GO:0052907; GO:0061157; GO:0070475; GO:0080009; GO:0120048; GO:0120049 16405 FUN_015275 933 1189 372 800 513 ptg000009l:8181802-8252428 Q90703 1.62e-30 Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2) Gallus gallus (Chicken) arginine catabolic process [GO:0006527]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of blood pressure [GO:0045776]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; prostaglandin secretion [GO:0032310]; regulation of cytokine production involved in inflammatory response [GO:1900015]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496] GO:0004517; GO:0005516; GO:0005634; GO:0005829; GO:0005886; GO:0006527; GO:0006809; GO:0006954; GO:0007263; GO:0009725; GO:0010181; GO:0012506; GO:0016491; GO:0018119; GO:0020037; GO:0031284; GO:0032310; GO:0032496; GO:0032755; GO:0032757; GO:0042742; GO:0045776; GO:0046872; GO:0050660; GO:0050661; GO:1900015 16406 FUN_015275 933 1189 372 800 513 ptg000009l:8181802-8252428 Q90703 2.26e-25 Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2) Gallus gallus (Chicken) arginine catabolic process [GO:0006527]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of blood pressure [GO:0045776]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; prostaglandin secretion [GO:0032310]; regulation of cytokine production involved in inflammatory response [GO:1900015]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496] GO:0004517; GO:0005516; GO:0005634; GO:0005829; GO:0005886; GO:0006527; GO:0006809; GO:0006954; GO:0007263; GO:0009725; GO:0010181; GO:0012506; GO:0016491; GO:0018119; GO:0020037; GO:0031284; GO:0032310; GO:0032496; GO:0032755; GO:0032757; GO:0042742; GO:0045776; GO:0046872; GO:0050660; GO:0050661; GO:1900015 16407 FUN_015274 220 687 337 469 905 NA NA NA NA NA NA NA 16408 FUN_015277 0 0 6 0 0 NA NA NA NA NA NA NA 16409 FUN_015276 1152 1054 1029 343 640 ptg000009l:8263484-8288008 Q90703 1.82e-31 Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2) Gallus gallus (Chicken) arginine catabolic process [GO:0006527]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of blood pressure [GO:0045776]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; prostaglandin secretion [GO:0032310]; regulation of cytokine production involved in inflammatory response [GO:1900015]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496] GO:0004517; GO:0005516; GO:0005634; GO:0005829; GO:0005886; GO:0006527; GO:0006809; GO:0006954; GO:0007263; GO:0009725; GO:0010181; GO:0012506; GO:0016491; GO:0018119; GO:0020037; GO:0031284; GO:0032310; GO:0032496; GO:0032755; GO:0032757; GO:0042742; GO:0045776; GO:0046872; GO:0050660; GO:0050661; GO:1900015 16410 FUN_015276 1152 1054 1029 343 640 ptg000009l:8263484-8288008 Q90703 3.28e-26 Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2) Gallus gallus (Chicken) arginine catabolic process [GO:0006527]; defense response to bacterium [GO:0042742]; inflammatory response [GO:0006954]; negative regulation of blood pressure [GO:0045776]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide mediated signal transduction [GO:0007263]; peptidyl-cysteine S-nitrosylation [GO:0018119]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; prostaglandin secretion [GO:0032310]; regulation of cytokine production involved in inflammatory response [GO:1900015]; response to hormone [GO:0009725]; response to lipopolysaccharide [GO:0032496] GO:0004517; GO:0005516; GO:0005634; GO:0005829; GO:0005886; GO:0006527; GO:0006809; GO:0006954; GO:0007263; GO:0009725; GO:0010181; GO:0012506; GO:0016491; GO:0018119; GO:0020037; GO:0031284; GO:0032310; GO:0032496; GO:0032755; GO:0032757; GO:0042742; GO:0045776; GO:0046872; GO:0050660; GO:0050661; GO:1900015 16411 FUN_015279 4 0 5 5 8 NA NA NA NA NA NA NA 16412 FUN_007119 217 174 85 234 206 ptg000001l:20723805-20724911 Q498J9 1.1e-54 Metallo-beta-lactamase domain-containing protein 1 (EC 3.1.27.-) (Endoribonuclease MBLAC1) Xenopus laevis (African clawed frog) histone mRNA metabolic process [GO:0008334]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087] GO:0004521; GO:0005634; GO:0005737; GO:0005829; GO:0008334; GO:0046872; GO:1900087 16413 FUN_007118 3026 4031 1838 2413 2248 ptg000001l:20719461-20721872 Q9XVI9 6.55e-30 Myosin-2 essential light chain Caenorhabditis elegans mitotic cytokinesis [GO:0000281] GO:0000281; GO:0005509; GO:0005737; GO:0015629; GO:0016460 16414 FUN_007891 1233 962 332 917 1251 NA NA NA NA NA NA NA 16415 FUN_038414 10 49 0 16 0 NA NA NA NA NA NA NA 16416 FUN_038416 2312 2089 949 1459 1203 ptg000027l:6966933-6967644 Q8L7C9 5.09e-33 Glutathione S-transferase U20 (AtGSTU20) (EC 2.5.1.18) (FIN219-interacting protein 1) (GST class-tau member 20) Arabidopsis thaliana (Mouse-ear cress) glutathione metabolic process [GO:0006749]; regulation of response to red or far red light [GO:2000030]; response to gravity [GO:0009629]; toxin catabolic process [GO:0009407] GO:0004364; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006749; GO:0009407; GO:0009507; GO:0009629; GO:0019899; GO:0043295; GO:0048046; GO:2000030 16417 FUN_028849 2385 6675 1681 82 6904 NA NA NA NA NA NA NA 16418 FUN_038410 4812 8500 4019 5681 3509 NA NA NA NA NA NA NA 16419 FUN_038411 3959 1509 4194 5250 2811 NA NA NA NA NA NA NA 16420 FUN_038412 0 0 31 74 9 NA NA NA NA NA NA NA 16421 FUN_038413 0 0 0 8 0 NA NA NA NA NA NA NA 16422 FUN_028842 2914 2399 951 1995 1433 NA NA NA NA NA NA NA 16423 FUN_023811 0 0 21 7 0 NA NA NA NA NA NA NA 16424 FUN_028840 539 662 463 808 892 NA NA NA NA NA NA NA 16425 FUN_028841 524 477 316 392 524 NA NA NA NA NA NA NA 16426 FUN_023817 0 0 0 0 7 NA NA NA NA NA NA NA 16427 FUN_005987 64 106 48 43 4 ptg000001l:6479809-6480670 P35346 1.83e-24 Somatostatin receptor type 5 (SS-5-R) (SS5-R) (SS5R) (SST5) Homo sapiens (Human) cellular response to glucocorticoid stimulus [GO:0071385]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cell population proliferation [GO:0008285]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytokinesis [GO:0032467]; regulation of insulin secretion [GO:0050796] GO:0004930; GO:0004994; GO:0005886; GO:0007186; GO:0007187; GO:0007218; GO:0008285; GO:0032467; GO:0042277; GO:0042593; GO:0042923; GO:0043005; GO:0050796; GO:0071385 16428 FUN_019601 3 0 0 7 0 NA NA NA NA NA NA NA 16429 FUN_019603 15 0 0 0 7 NA NA NA NA NA NA NA 16430 FUN_005287 8 1 3 17 7 NA NA NA NA NA NA NA 16431 FUN_005988 30 22 23 10 0 NA NA NA NA NA NA NA 16432 FUN_044158 1 5 10 9 21 NA NA NA NA NA NA NA 16433 FUN_041227 0 7 0 9 7 NA NA NA NA NA NA NA 16434 FUN_044159 7 11 61 54 227 NA NA NA NA NA NA NA 16435 FUN_041226 4 19 6 24 0 NA NA NA NA NA NA NA 16436 FUN_013344 65 895 895 385 989 NA NA NA NA NA NA NA 16437 FUN_003625 64 142 18 0 28 ntLink_8:13667611-13669268 P19477 1.46e-37 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 16438 FUN_013646 121 43 121 134 144 ptg000008l:25007649-25010754 Q9I830 1.4e-64 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 16439 FUN_013349 0 0 0 0 6 NA NA NA NA NA NA NA 16440 FUN_013348 139 0 0 53 94 NA NA NA NA NA NA NA 16441 FUN_027015 0 0 0 2 16 NA NA NA NA NA NA NA 16442 FUN_027010 0 0 1 0 70 NA NA NA NA NA NA NA 16443 FUN_027018 0 5 51 0 24 NA NA NA NA NA NA NA 16444 FUN_030883 0 0 7 30 3 NA NA NA NA NA NA NA 16445 FUN_030881 1935 1448 848 1455 1057 NA NA NA NA NA NA NA 16446 FUN_030880 518 576 269 331 336 NA NA NA NA NA NA NA 16447 FUN_003899 1779 1315 657 1130 981 NA NA NA NA NA NA NA 16448 FUN_017250 11 32 26 16 164 NA NA NA NA NA NA NA 16449 FUN_017255 0 1 73 91 3 NA NA NA NA NA NA NA 16450 FUN_017257 9 0 133 0 304 NA NA NA NA NA NA NA 16451 FUN_017256 0 0 21 59 3 NA NA NA NA NA NA NA 16452 FUN_003621 409 755 489 13 322 NA NA NA NA NA NA NA 16453 FUN_007663 0 0 17 0 99 NA NA NA NA NA NA NA 16454 FUN_026719 1050 396 270 675 657 NA NA NA NA NA NA NA 16455 FUN_003620 114 329 203 0 206 NA NA NA NA NA NA NA 16456 FUN_031469 1935 1617 1230 3222 1972 NA NA NA NA NA NA NA 16457 FUN_007668 1922 1364 701 1638 328 NA NA NA NA NA NA NA 16458 FUN_003623 6 2 3 0 0 NA NA NA NA NA NA NA 16459 FUN_004350 1784 1300 758 1342 1667 NA NA NA NA NA NA NA 16460 FUN_004351 5639 5589 3772 4385 1476 NA NA NA NA NA NA NA 16461 FUN_004352 0 0 14 0 0 NA NA NA NA NA NA NA 16462 FUN_004353 0 0 16 8 0 NA NA NA NA NA NA NA 16463 FUN_004355 1458 1983 861 1049 716 NA NA NA NA NA NA NA 16464 FUN_004356 1225 731 556 810 610 ntLink_8:22286402-22286576 Q9UM11 3.64e-23 Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; DNA repair [GO:0006281]; lens fiber cell differentiation [GO:0070306]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of cellular senescence [GO:2000773]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein K11-linked ubiquitination [GO:0070979]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005829; GO:0006281; GO:0007095; GO:0007346; GO:0008284; GO:0010997; GO:0031145; GO:0031965; GO:0040020; GO:0051301; GO:0051445; GO:0070306; GO:0070979; GO:1904668; GO:1905786; GO:1990757; GO:2000773 16465 FUN_004357 3376 2107 1613 2156 1544 NA NA NA NA NA NA NA 16466 FUN_004358 1880 2454 1145 1253 1150 NA NA NA NA NA NA NA 16467 FUN_004359 8400 8390 4657 7314 3839 ntLink_8:22313999-22324173 Q4IQ08 3.6e-33 GPI-anchored wall transfer protein 1 (EC 2.3.-.-) Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0006506; GO:0008374 16468 FUN_027908 966 329 667 462 252 ptg000021l:12992969-13021122 P10978 2.41e-26 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 16469 FUN_027908 966 329 667 462 252 ptg000021l:12992969-13021122 P10978 2.41e-26 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 16470 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 7.84e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16471 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 1.38e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16472 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 3.57e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16473 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 4.24e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16474 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 1.68e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16475 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 7.58e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16476 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 2.48e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16477 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 4.53e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16478 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 7.15e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16479 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 3.59e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16480 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 5.29e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16481 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 1.96e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16482 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 2.44e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16483 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 8.14e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16484 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 1.18e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16485 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 5.57e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16486 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 1.17e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16487 FUN_018169 256 74 251 145 498 ptg000012l:5274172-5278970 Q96AY4 8.31e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16488 FUN_018166 0 18 4 0 19 NA NA NA NA NA NA NA 16489 FUN_027903 9447 5780 4577 8058 5736 ptg000021l:12901234-12912999 P51655 2.1e-49 Glypican-4 (K-glypican) [Cleaved into: Secreted glypican-4] Mus musculus (Mouse) cell migration [GO:0016477]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of presynapse assembly [GO:1905606]; regulation of protein localization to membrane [GO:1905475]; regulation of signal transduction [GO:0009966]; synaptic membrane adhesion [GO:0099560]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005796; GO:0009897; GO:0009966; GO:0009986; GO:0016055; GO:0016477; GO:0042734; GO:0045202; GO:0062023; GO:0098696; GO:0098978; GO:0099560; GO:1905475; GO:1905606 16490 FUN_018164 36 0 22 51 67 NA NA NA NA NA NA NA 16491 FUN_027901 367 694 271 574 346 NA NA NA NA NA NA NA 16492 FUN_027906 11 2 27 0 0 NA NA NA NA NA NA NA 16493 FUN_027904 0 13 8 0 145 NA NA NA NA NA NA NA 16494 FUN_018161 258 409 229 579 409 NA NA NA NA NA NA NA 16495 FUN_032685 3071 2204 1289 3823 2372 NA NA NA NA NA NA NA 16496 FUN_032684 97 0 0 10 5 NA NA NA NA NA NA NA 16497 FUN_026059 689 423 436 747 1253 NA NA NA NA NA NA NA 16498 FUN_026058 918 813 673 1324 1177 NA NA NA NA NA NA NA 16499 FUN_026057 1945 886 1051 1273 1368 NA NA NA NA NA NA NA 16500 FUN_026056 347 592 394 311 1348 NA NA NA NA NA NA NA 16501 FUN_026055 0 79 234 426 0 NA NA NA NA NA NA NA 16502 FUN_026054 1511 1645 700 1413 1159 NA NA NA NA NA NA NA 16503 FUN_026053 1327 1108 738 1493 1354 NA NA NA NA NA NA NA 16504 FUN_026052 2336 2949 858 2930 2006 NA NA NA NA NA NA NA 16505 FUN_026051 18 52 14 71 63 ptg000020l:4110184-4112029 Q8N0W4 1.24e-98 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 16506 FUN_026050 0 0 1 0 23 NA NA NA NA NA NA NA 16507 FUN_040352 0 0 0 0 13 ptg000031l:7339527-7341349 Q7RTR2 3.98e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16508 FUN_040352 0 0 0 0 13 ptg000031l:7339527-7341349 Q7RTR2 3.98e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16509 FUN_040352 0 0 0 0 13 ptg000031l:7339527-7341349 Q7RTR2 2.37e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16510 FUN_040352 0 0 0 0 13 ptg000031l:7339527-7341349 Q7RTR2 2.37e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16511 FUN_005134 246 292 340 224 1636 NA NA NA NA NA NA NA 16512 FUN_025508 9 14 5 1 4 NA NA NA NA NA NA NA 16513 FUN_025509 169 94 131 130 103 NA NA NA NA NA NA NA 16514 FUN_025504 138 75 69 178 80 ptg000019l:3632899-3634882 Q2YDN1 2.63e-30 G protein-coupled receptor 161 Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0055037; GO:0060170; GO:1901621 16515 FUN_025505 78 19 47 15 30 NA NA NA NA NA NA NA 16516 FUN_025506 55 27 74 83 98 NA NA NA NA NA NA NA 16517 FUN_025500 450 348 47 269 54 NA NA NA NA NA NA NA 16518 FUN_025501 61 93 37 106 19 NA NA NA NA NA NA NA 16519 FUN_025502 151 123 108 172 215 ptg000019l:3620626-3626212 P23795 1.16e-31 Acetylcholinesterase (AChE) (EC 3.1.1.7) Bos taurus (Bovine) acetylcholine catabolic process [GO:0006581]; choline metabolic process [GO:0019695] GO:0001540; GO:0003990; GO:0005615; GO:0005886; GO:0006581; GO:0019695; GO:0045202 16520 FUN_025503 306 305 219 406 214 NA NA NA NA NA NA NA 16521 FUN_040354 0 0 0 0 19 NA NA NA NA NA NA NA 16522 FUN_018788 0 0 0 23 0 NA NA NA NA NA NA NA 16523 FUN_018781 130 32 22 13 544 NA NA NA NA NA NA NA 16524 FUN_018787 4 0 0 2 10 NA NA NA NA NA NA NA 16525 FUN_018784 0 0 0 8 0 NA NA NA NA NA NA NA 16526 FUN_036510 417 561 367 508 733 ptg000025l:19078381-19083042 Q6PBT5 1.28e-98 Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 (EC 1.8.1.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0016491; GO:0030017; GO:0050660 16527 FUN_003707 4218 2344 4352 5533 1282 NA NA NA NA NA NA NA 16528 FUN_003704 42905 17969 4247 9092 3888 NA NA NA NA NA NA NA 16529 FUN_004723 663 305 467 782 816 NA NA NA NA NA NA NA 16530 FUN_022538 1105 1140 375 849 912 NA NA NA NA NA NA NA 16531 FUN_007199 0 271 0 0 0 NA NA NA NA NA NA NA 16532 FUN_007198 96 386 71 193 618 NA NA NA NA NA NA NA 16533 FUN_039935 9592 5133 4744 9166 7284 NA NA NA NA NA NA NA 16534 FUN_007193 97 348 80 195 594 NA NA NA NA NA NA NA 16535 FUN_007192 6 8 11 3 88 NA NA NA NA NA NA NA 16536 FUN_007191 0 252 0 0 0 NA NA NA NA NA NA NA 16537 FUN_007190 90 360 76 201 578 NA NA NA NA NA NA NA 16538 FUN_007197 5 11 10 3 69 NA NA NA NA NA NA NA 16539 FUN_007196 10 3 35 6 202 NA NA NA NA NA NA NA 16540 FUN_007194 0 247 0 0 0 NA NA NA NA NA NA NA 16541 FUN_003705 33834 19974 4704 7348 4606 NA NA NA NA NA NA NA 16542 FUN_004722 20018 21859 14332 23845 14477 ntLink_8:26245501-26245920 B0VYY5 4.09e-36 Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) Notamacropus parma (Parma wallaby) (Macropus parma) mitochondrial electron transport, cytochrome c to oxygen [GO:0006123] GO:0005751; GO:0006123; GO:0046872 16543 FUN_005908 8948 4547 3928 6195 5043 ptg000001l:5565845-5579335 Q16720 1.93e-136 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16544 FUN_005908 8948 4547 3928 6195 5043 ptg000001l:5565845-5579335 Q16720 2.05e-42 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16545 FUN_005908 8948 4547 3928 6195 5043 ptg000001l:5565845-5579335 Q16720 1.25e-37 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16546 FUN_005908 8948 4547 3928 6195 5043 ptg000001l:5565845-5579335 Q16720 1.69e-23 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16547 FUN_005909 749 1282 466 629 576 ptg000001l:5579931-5580898 A7S3I2 1.05e-32 BBSome-interacting protein 1 (BBSome-interacting protein of 10 kDa) Nematostella vectensis (Starlet sea anemone) cilium assembly [GO:0060271]; receptor localization to non-motile cilium [GO:0097500] GO:0005737; GO:0034464; GO:0060271; GO:0097500 16548 FUN_005906 4039 1730 1562 2299 1637 ptg000001l:5532519-5542596 Q16720 1.36e-48 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16549 FUN_005906 4039 1730 1562 2299 1637 ptg000001l:5532519-5542596 Q16720 8.7e-28 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16550 FUN_005907 5315 4657 2064 3352 2233 ptg000001l:5545919-5558853 Q16720 2.76e-56 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16551 FUN_005907 5315 4657 2064 3352 2233 ptg000001l:5545919-5558853 Q16720 3.98e-37 Plasma membrane calcium-transporting ATPase 3 (PMCA3) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005388; GO:0005516; GO:0005524; GO:0005886; GO:0006874; GO:0015085; GO:0016887; GO:0019829; GO:0030165; GO:0034220; GO:0042734; GO:0043231; GO:0046872; GO:0051480; GO:0098688; GO:0098978; GO:0098982; GO:1903561; GO:1903779; GO:1905056; GO:1990032; GO:1990034 16552 FUN_005904 254 212 241 154 145 NA NA NA NA NA NA NA 16553 FUN_005905 497 447 241 339 393 NA NA NA NA NA NA NA 16554 FUN_005900 27 90 15 60 36 NA NA NA NA NA NA NA 16555 FUN_005901 6755 3830 3412 6247 5400 ptg000001l:5458941-5493698 O94915 2.25e-26 Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein) Homo sapiens (Human) cell morphogenesis [GO:0000902]; neuron projection development [GO:0031175] GO:0000902; GO:0005938; GO:0030427; GO:0031175 16556 FUN_021084 2 0 8 3 15 NA NA NA NA NA NA NA 16557 FUN_021086 7 0 0 3 68 NA NA NA NA NA NA NA 16558 FUN_021089 3 0 4 0 10 NA NA NA NA NA NA NA 16559 FUN_021088 184 0 133 0 481 ptg000016l:651271-653376 Q6LAF1 2.83e-49 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 16560 FUN_034991 2460 1306 1269 1805 1474 NA NA NA NA NA NA NA 16561 FUN_034990 1260 982 669 920 929 NA NA NA NA NA NA NA 16562 FUN_034993 262 152 407 250 312 ptg000025l:2599456-2600992 P43140 2.8e-30 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Rattus norvegicus (Rat) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adrenergic receptor signaling pathway [GO:0071875]; adult heart development [GO:0007512]; aging [GO:0007568]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; organ growth [GO:0035265]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate [GO:0010460]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of blood pressure [GO:0008217]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008217; GO:0009410; GO:0009725; GO:0010259; GO:0010460; GO:0010507; GO:0010613; GO:0016020; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035265; GO:0042734; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071875; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 16563 FUN_034992 0 0 13 0 5 NA NA NA NA NA NA NA 16564 FUN_034995 0 6 129 42 4 NA NA NA NA NA NA NA 16565 FUN_034994 1345 1365 1175 1341 2033 ptg000025l:2602204-2603323 P43141 1.31e-30 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 16566 FUN_034997 967 766 602 1064 798 ptg000025l:2633436-2634510 P18762 8.98e-27 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Mus musculus (Mouse) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adrenergic receptor signaling pathway [GO:0071875]; associative learning [GO:0008306]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; cellular response to hypoxia [GO:0071456]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diaphragm contraction [GO:0002086]; diet induced thermogenesis [GO:0002024]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled receptor signaling pathway [GO:0007186]; heat generation [GO:0031649]; negative regulation of angiogenesis [GO:0016525]; negative regulation of inflammatory response [GO:0050728]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of ossification [GO:0030279]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of urine volume [GO:0035811]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of heart contraction [GO:0045823]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of the force of heart contraction by epinephrine [GO:0003059]; positive regulation of transcription by RNA polymerase II [GO:0045944]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; receptor-mediated endocytosis [GO:0006898]; regulation of calcium ion transport [GO:0051924]; regulation of sensory perception of pain [GO:0051930]; regulation of sodium ion transport [GO:0002028]; regulation of systemic arterial blood pressure by norepinephrine-epinephrine [GO:0001993]; response to catecholamine [GO:0071869]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; vasodilation [GO:0042311]; wound healing [GO:0042060] GO:0001540; GO:0001965; GO:0001993; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0002086; GO:0003059; GO:0004930; GO:0004941; GO:0005634; GO:0005737; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0005901; GO:0006366; GO:0006898; GO:0006939; GO:0007186; GO:0007189; GO:0007190; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0010739; GO:0010765; GO:0015459; GO:0016020; GO:0016324; GO:0016525; GO:0019899; GO:0030279; GO:0030424; GO:0030425; GO:0030501; GO:0031649; GO:0031713; GO:0032781; GO:0032809; GO:0035249; GO:0035255; GO:0035811; GO:0040015; GO:0042060; GO:0042311; GO:0042383; GO:0042802; GO:0042803; GO:0043065; GO:0043197; GO:0043231; GO:0043235; GO:0043268; GO:0043410; GO:0044877; GO:0045211; GO:0045453; GO:0045823; GO:0045944; GO:0045986; GO:0048633; GO:0050728; GO:0050873; GO:0051380; GO:0051721; GO:0051924; GO:0051930; GO:0060079; GO:0061885; GO:0071456; GO:0071869; GO:0071875; GO:0071880; GO:0071902; GO:0090331; GO:0090722; GO:0098685; GO:0098793; GO:0098978; GO:0098992; GO:0099171; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1905665; GO:2000969 16567 FUN_018469 129 108 197 121 166 NA NA NA NA NA NA NA 16568 FUN_034999 736 498 125 203 24 ptg000025l:2652418-2656247 Q02556 8.02e-27 Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP) Homo sapiens (Human) autophagy [GO:0006914]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to type II interferon [GO:0071346]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; dendritic cell differentiation [GO:0097028]; follicular B cell differentiation [GO:0002316]; germinal center B cell differentiation [GO:0002314]; immune response [GO:0006955]; immune system process [GO:0002376]; myeloid cell differentiation [GO:0030099]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phagocytosis [GO:0006909]; plasmacytoid dendritic cell differentiation [GO:0002273]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type II interferon production [GO:0032729]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type I interferon production [GO:0032479] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0002273; GO:0002314; GO:0002316; GO:0002376; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0006909; GO:0006914; GO:0006955; GO:0030099; GO:0032479; GO:0032729; GO:0032735; GO:0042742; GO:0042832; GO:0045944; GO:0071222; GO:0071346; GO:0097028; GO:1990837 16569 FUN_034998 788 502 226 582 326 ptg000025l:2639397-2649479 Q15306 5.48e-27 Interferon regulatory factor 4 (IRF-4) (Lymphocyte-specific interferon regulatory factor) (LSIRF) (Multiple myeloma oncogene 1) (NF-EM5) Homo sapiens (Human) defense response to protozoan [GO:0042832]; histone H3 acetylation [GO:0043966]; histone H4 acetylation [GO:0043967]; immune system process [GO:0002376]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of toll-like receptor signaling pathway [GO:0034122]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of DNA binding [GO:0043388]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of T-helper cell differentiation [GO:0045622]; regulation of transcription by RNA polymerase II [GO:0006357]; T cell activation [GO:0042110]; T-helper 17 cell lineage commitment [GO:0072540] GO:0000785; GO:0000786; GO:0000978; GO:0000981; GO:0001228; GO:0002376; GO:0003700; GO:0003713; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0016020; GO:0032733; GO:0032736; GO:0032743; GO:0032753; GO:0034122; GO:0042110; GO:0042832; GO:0043011; GO:0043388; GO:0043565; GO:0043966; GO:0043967; GO:0045622; GO:0045893; GO:0045944; GO:0072540; GO:0120162; GO:1990837 16570 FUN_022535 18279 10057 5719 17260 10341 ptg000016l:10244648-10246155 B8UU51 1.36e-164 Galaxin-2 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16571 FUN_004606 43 0 86 217 250 NA NA NA NA NA NA NA 16572 FUN_006267 5 0 19 0 14 NA NA NA NA NA NA NA 16573 FUN_006248 3670 2504 1761 3412 3295 ptg000001l:9708285-9724426 Q9Z0X1 6.91e-34 Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; cellular response to aldosterone [GO:1904045]; cellular response to estradiol stimulus [GO:0071392]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nitric oxide [GO:0071732]; cellular response to oxygen-glucose deprivation [GO:0090650]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mitochondrial respiratory chain complex assembly [GO:0033108]; mitochondrial respiratory chain complex I assembly [GO:0032981]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; positive regulation of apoptotic process [GO:0043065]; positive regulation of necroptotic process [GO:0060545]; positive regulation of neuron apoptotic process [GO:0043525]; programmed cell death [GO:0012501]; protein import into mitochondrial intermembrane space [GO:0045041]; regulation of apoptotic DNA fragmentation [GO:1902510]; response to ischemia [GO:0002931]; response to L-glutamate [GO:1902065]; response to oxidative stress [GO:0006979]; response to toxic substance [GO:0009636] GO:0002931; GO:0003677; GO:0003954; GO:0004174; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005758; GO:0005829; GO:0006915; GO:0006919; GO:0006979; GO:0008637; GO:0009636; GO:0012501; GO:0016174; GO:0016651; GO:0030182; GO:0032981; GO:0033108; GO:0043065; GO:0043525; GO:0045041; GO:0046983; GO:0048471; GO:0051402; GO:0060545; GO:0070059; GO:0070301; GO:0071392; GO:0071732; GO:0071949; GO:0072572; GO:0090650; GO:1902065; GO:1902510; GO:1904045 16574 FUN_006249 113 131 74 126 149 NA NA NA NA NA NA NA 16575 FUN_035190 1041 924 692 1166 1055 NA NA NA NA NA NA NA 16576 FUN_006240 1772 512 6 1880 1324 NA NA NA NA NA NA NA 16577 FUN_006241 443 158 0 522 266 NA NA NA NA NA NA NA 16578 FUN_006242 4640 2914 2041 3064 3229 NA NA NA NA NA NA NA 16579 FUN_006243 416 510 530 783 715 ptg000001l:9672291-9686016 Q805E5 1.65e-73 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 16580 FUN_006243 416 510 530 783 715 ptg000001l:9672291-9686016 Q805E5 1.15e-70 Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase 1) (D4ST-1) (zD4ST-1) Danio rerio (Zebrafish) (Brachydanio rerio) carbohydrate biosynthetic process [GO:0016051]; dermatan sulfate proteoglycan metabolic process [GO:0050655] GO:0000139; GO:0001537; GO:0008146; GO:0016051; GO:0050655 16581 FUN_006244 0 0 0 0 19 NA NA NA NA NA NA NA 16582 FUN_006245 235 81 48 133 130 NA NA NA NA NA NA NA 16583 FUN_006246 605 805 231 1191 711 NA NA NA NA NA NA NA 16584 FUN_006247 0 1 3 26 0 NA NA NA NA NA NA NA 16585 FUN_029211 308 112 165 128 362 ptg000022l:9341537-9346451 Q9BYN7 3.5e-36 Zinc finger protein 341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0001216; GO:0003677; GO:0005634; GO:0006355; GO:0046872 16586 FUN_004604 0 0 53 8 25 NA NA NA NA NA NA NA 16587 FUN_027157 0 0 19 0 44 NA NA NA NA NA NA NA 16588 FUN_029215 386 208 83 144 86 NA NA NA NA NA NA NA 16589 FUN_035646 269 139 169 160 163 ptg000025l:10286435-10290258 Q9FWW9 6.51e-42 Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832] GO:0004499; GO:0050660; GO:0050661; GO:0050832 16590 FUN_035647 159 157 169 123 198 NA NA NA NA NA NA NA 16591 FUN_035644 134 74 28 150 73 NA NA NA NA NA NA NA 16592 FUN_035645 1507 846 654 1809 1273 ptg000025l:10272429-10285856 Q94BV5 5.56e-44 Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0004499; GO:0050660; GO:0050661 16593 FUN_035645 1507 846 654 1809 1273 ptg000025l:10272429-10285856 Q94BV5 1.75e-31 Flavin-containing monooxygenase FMO GS-OX-like 4 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0000325; GO:0004499; GO:0050660; GO:0050661 16594 FUN_004605 452 174 732 914 822 ntLink_8:24797367-24824832 Q95SX7 2.47e-29 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 16595 FUN_035640 178 47 47 103 65 NA NA NA NA NA NA NA 16596 FUN_035641 317 180 254 474 141 NA NA NA NA NA NA NA 16597 FUN_035648 52 142 225 270 129 ptg000025l:10300191-10306835 Q8N165 5.76e-24 Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1-interacting kinase 1-like) Homo sapiens (Human) meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0006468; GO:0051321; GO:0106310 16598 FUN_035648 52 142 225 270 129 ptg000025l:10300191-10306835 Q8N165 1.57e-23 Serine/threonine-protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1-interacting kinase 1-like) Homo sapiens (Human) meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0006468; GO:0051321; GO:0106310 16599 FUN_035649 82 15 1 11 0 NA NA NA NA NA NA NA 16600 FUN_003997 47 21 33 113 37 ntLink_8:17844447-17845545 P51049 9.36e-25 Melatonin receptor type 1B-B (Mel-1B-R-B) (Mel1b receptor B) (Melatonin receptor Mel1b Z2.6-4) (zMel1b-1) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186]; rhythmic process [GO:0048511] GO:0004930; GO:0005886; GO:0007186; GO:0008502; GO:0048511 16601 FUN_003996 210 344 274 594 319 NA NA NA NA NA NA NA 16602 FUN_003993 146 133 593 0 603 NA NA NA NA NA NA NA 16603 FUN_003992 3957 7697 2577 6594 3527 NA NA NA NA NA NA NA 16604 FUN_003991 2623 5374 1665 4116 2104 ntLink_8:17800083-17800698 Q0GGW5 3.04e-23 Serine/threonine-protein kinase STK11 (EC 2.7.11.1) (Liver kinase B1 homolog) (LKB1) Gallus gallus (Chicken) activation of protein kinase activity [GO:0032147]; cell cycle [GO:0007049]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to starvation [GO:0009267]; establishment of cell polarity [GO:0030010]; glucose homeostasis [GO:0042593]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell growth [GO:0030308]; positive regulation of vesicle transport along microtubule [GO:1901610]; protein autophosphorylation [GO:0046777]; protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; regulation of cell growth [GO:0001558]; regulation of Wnt signaling pathway [GO:0030111]; response to ionizing radiation [GO:0010212]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; vasculature development [GO:0001944] GO:0000287; GO:0001558; GO:0001944; GO:0002039; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0006468; GO:0006470; GO:0006974; GO:0007049; GO:0007165; GO:0009267; GO:0009410; GO:0010212; GO:0016020; GO:0019901; GO:0030010; GO:0030111; GO:0030295; GO:0030308; GO:0032147; GO:0042593; GO:0046777; GO:0072332; GO:0090090; GO:0106310; GO:1901610 16605 FUN_003990 1013 788 862 1195 1074 ntLink_8:17788584-17798029 Q8LB54 6.97e-22 Pre-mRNA-splicing factor 38 Arabidopsis thaliana (Mouse-ear cress) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0006397; GO:0008380; GO:0071011 16606 FUN_003999 110 170 49 155 83 NA NA NA NA NA NA NA 16607 FUN_004602 5 0 0 16 2 NA NA NA NA NA NA NA 16608 FUN_032030 245 126 104 61 132 ptg000023l:28091710-28101003 B8VIU6 1.26e-32 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16609 FUN_032031 0 0 9 0 27 NA NA NA NA NA NA NA 16610 FUN_032032 6 7 7 0 13 ptg000023l:28102218-28104112 B8VIU6 7.16e-26 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16611 FUN_032033 68 0 14 31 26 ptg000023l:28108139-28138351 B8VIU6 2.99e-29 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16612 FUN_032033 68 0 14 31 26 ptg000023l:28108139-28138351 B8VIU6 1.04e-28 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16613 FUN_032034 34 0 7 5 34 ptg000023l:28140281-28140764 B8VIU6 2.96e-31 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 16614 FUN_032035 1355 1659 725 838 655 ptg000023l:28145796-28278448 P21328 9.23e-44 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 16615 FUN_032036 12 140 41 7 171 NA NA NA NA NA NA NA 16616 FUN_032037 242 2519 853 1100 1542 NA NA NA NA NA NA NA 16617 FUN_032038 1245 969 779 542 905 NA NA NA NA NA NA NA 16618 FUN_032039 2603 4010 1969 2267 3023 NA NA NA NA NA NA NA 16619 FUN_001739 48 17 101 141 133 ntLink_6:15468967-15470497 A7S4N4 8.68e-56 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 16620 FUN_001738 9 17 17 2 0 NA NA NA NA NA NA NA 16621 FUN_001731 2630 2443 841 1602 1620 ntLink_6:15413379-15420351 Q9Y6N5 4e-22 Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.8) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase) Homo sapiens (Human) sulfide oxidation, using sulfide:quinone oxidoreductase [GO:0070221] GO:0005739; GO:0005743; GO:0048038; GO:0070221; GO:0070224; GO:0071949; GO:0106436 16622 FUN_001730 260 169 69 131 196 NA NA NA NA NA NA NA 16623 FUN_001733 684 366 543 450 389 NA NA NA NA NA NA NA 16624 FUN_001732 0 0 17 24 3 NA NA NA NA NA NA NA 16625 FUN_001735 2330 3101 1289 1958 1167 NA NA NA NA NA NA NA 16626 FUN_001734 4542 6751 6223 6158 1183 NA NA NA NA NA NA NA 16627 FUN_001737 0 5 14 16 0 NA NA NA NA NA NA NA 16628 FUN_001736 0 0 16 53 104 NA NA NA NA NA NA NA 16629 FUN_043809 11 3 237 14 8 NA NA NA NA NA NA NA 16630 FUN_033088 4 0 0 0 15 NA NA NA NA NA NA NA 16631 FUN_043805 0 25 3 0 0 NA NA NA NA NA NA NA 16632 FUN_043807 29 8 0 44 30 NA NA NA NA NA NA NA 16633 FUN_043806 0 17 0 2 0 NA NA NA NA NA NA NA 16634 FUN_043803 0 1 6 0 0 NA NA NA NA NA NA NA 16635 FUN_043802 1 0 7 0 1 NA NA NA NA NA NA NA 16636 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16637 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16638 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16639 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16640 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16641 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16642 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16643 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16644 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 2.16e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16645 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 1.15e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16646 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 2.11e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16647 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 4.46e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16648 FUN_005296 335 208 96 419 274 ntLink_8:33738534-33748629 Q96AY4 1.94e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16649 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 3.58e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16650 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 6.46e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16651 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 8.28e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16652 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 8.31e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16653 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 1.79e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16654 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 1.22e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16655 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 1.39e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16656 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 2.41e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16657 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 2.43e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16658 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 2.4e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16659 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 4.61e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16660 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 7.36e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16661 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 3.94e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16662 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 6.66e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16663 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 6.63e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16664 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 1.95e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16665 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 6.17e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16666 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 5.54e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16667 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 2e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16668 FUN_005292 321 128 364 678 362 ntLink_8:33656656-33663627 Q96AY4 5.8e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16669 FUN_005290 0 0 12 34 0 NA NA NA NA NA NA NA 16670 FUN_005291 0 13 0 0 0 NA NA NA NA NA NA NA 16671 FUN_005298 0 0 0 0 6 NA NA NA NA NA NA NA 16672 FUN_007676 4743 2144 1358 2022 2106 NA NA NA NA NA NA NA 16673 FUN_007674 410 407 281 663 1167 ptg000002l:3105025-3106752 Q5DU56 4.13e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16674 FUN_007674 410 407 281 663 1167 ptg000002l:3105025-3106752 Q5DU56 4.82e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16675 FUN_007674 410 407 281 663 1167 ptg000002l:3105025-3106752 Q5DU56 1.36e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16676 FUN_007674 410 407 281 663 1167 ptg000002l:3105025-3106752 Q5DU56 1.4e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16677 FUN_007674 410 407 281 663 1167 ptg000002l:3105025-3106752 Q5DU56 1.61e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16678 FUN_007674 410 407 281 663 1167 ptg000002l:3105025-3106752 Q5DU56 8.29e-27 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16679 FUN_007675 57 0 73 20 472 NA NA NA NA NA NA NA 16680 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 1.41e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16681 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 8.14e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16682 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 9e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16683 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 3.02e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16684 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 5.38e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16685 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 5.71e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16686 FUN_007672 12 88 74 79 72 ptg000002l:3054520-3059581 Q96AY4 1.63e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16687 FUN_007673 780 770 611 1483 1599 NA NA NA NA NA NA NA 16688 FUN_007671 627 324 253 680 445 NA NA NA NA NA NA NA 16689 FUN_007678 2924 3351 1766 2475 2387 NA NA NA NA NA NA NA 16690 FUN_007679 219 306 0 0 121 NA NA NA NA NA NA NA 16691 FUN_005128 77 57 0 41 47 NA NA NA NA NA NA NA 16692 FUN_005129 0 1 6 12 0 ntLink_8:31387590-31388736 P12256 5.56e-44 Penicillin acylase (EC 3.5.1.11) (Penicillin V amidase) (PVA) Lysinibacillus sphaericus (Bacillus sphaericus) response to antibiotic [GO:0046677] GO:0008953; GO:0046677 16693 FUN_032698 700 273 197 816 680 NA NA NA NA NA NA NA 16694 FUN_032699 5268 2652 1859 1412 2062 ptg000023l:35025734-35046194 Q5ZMW0 6.59e-32 Protein argonaute-4 (Argonaute4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) Gallus gallus (Chicken) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA catabolic process [GO:0006402] GO:0000932; GO:0003723; GO:0003727; GO:0004521; GO:0006402; GO:0016442; GO:0035198; GO:0035278 16695 FUN_032699 5268 2652 1859 1412 2062 ptg000023l:35025734-35046194 Q5ZMW0 1.82e-27 Protein argonaute-4 (Argonaute4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) Gallus gallus (Chicken) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA catabolic process [GO:0006402] GO:0000932; GO:0003723; GO:0003727; GO:0004521; GO:0006402; GO:0016442; GO:0035198; GO:0035278 16696 FUN_032699 5268 2652 1859 1412 2062 ptg000023l:35025734-35046194 Q5ZMW0 9.28e-24 Protein argonaute-4 (Argonaute4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) Gallus gallus (Chicken) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA catabolic process [GO:0006402] GO:0000932; GO:0003723; GO:0003727; GO:0004521; GO:0006402; GO:0016442; GO:0035198; GO:0035278 16697 FUN_032699 5268 2652 1859 1412 2062 ptg000023l:35025734-35046194 Q5ZMW0 3.91e-23 Protein argonaute-4 (Argonaute4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4) Gallus gallus (Chicken) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; mRNA catabolic process [GO:0006402] GO:0000932; GO:0003723; GO:0003727; GO:0004521; GO:0006402; GO:0016442; GO:0035198; GO:0035278 16698 FUN_032694 505 150 25 573 271 NA NA NA NA NA NA NA 16699 FUN_005121 1288 678 675 1197 1263 NA NA NA NA NA NA NA 16700 FUN_005122 2213 790 423 2622 891 NA NA NA NA NA NA NA 16701 FUN_032697 9 2 8 0 0 NA NA NA NA NA NA NA 16702 FUN_032690 1209 1791 1083 1891 1956 NA NA NA NA NA NA NA 16703 FUN_032691 214 241 150 232 259 NA NA NA NA NA NA NA 16704 FUN_032692 1858 1694 839 1377 986 NA NA NA NA NA NA NA 16705 FUN_032693 537 309 51 1039 420 NA NA NA NA NA NA NA 16706 FUN_033341 0 0 0 10 7 NA NA NA NA NA NA NA 16707 FUN_033340 208 10 147 1207 221 ptg000023l:42099365-42104311 Q96AY4 1.15e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16708 FUN_033340 208 10 147 1207 221 ptg000023l:42099365-42104311 Q96AY4 4.2e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16709 FUN_033340 208 10 147 1207 221 ptg000023l:42099365-42104311 Q96AY4 8.08e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16710 FUN_033340 208 10 147 1207 221 ptg000023l:42099365-42104311 Q96AY4 6.82e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16711 FUN_033340 208 10 147 1207 221 ptg000023l:42099365-42104311 Q96AY4 2.56e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16712 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 3.58e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16713 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 3.24e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16714 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 3.64e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16715 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 1.1e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16716 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 6.09e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16717 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 1.05e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16718 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 1.74e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16719 FUN_033343 0 0 6 0 27 ptg000023l:42144159-42147394 Q96AY4 6.62e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16720 FUN_033344 3 6 3 9 11 NA NA NA NA NA NA NA 16721 FUN_033349 31 33 33 22 35 NA NA NA NA NA NA NA 16722 FUN_033348 7 0 0 0 8 NA NA NA NA NA NA NA 16723 FUN_040571 0 0 0 26 0 NA NA NA NA NA NA NA 16724 FUN_032966 741 41 76 188 73 NA NA NA NA NA NA NA 16725 FUN_032967 0 0 0 0 21 NA NA NA NA NA NA NA 16726 FUN_032964 0 0 46 0 0 NA NA NA NA NA NA NA 16727 FUN_032965 0 0 0 0 24 NA NA NA NA NA NA NA 16728 FUN_032962 139 350 189 170 171 ptg000023l:38157479-38161479 P07687 2.85e-59 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Rattus norvegicus (Rat) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; cellular aromatic compound metabolic process [GO:0006725]; cellular response to glucocorticoid stimulus [GO:0071385]; cellular response to organic substance [GO:0071310]; diol biosynthetic process [GO:0034312]; epoxide metabolic process [GO:0097176]; liver development [GO:0001889]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636] GO:0001889; GO:0004301; GO:0005789; GO:0005886; GO:0006725; GO:0009636; GO:0014070; GO:0016020; GO:0019369; GO:0019439; GO:0019899; GO:0033961; GO:0034312; GO:0043231; GO:0071310; GO:0071385; GO:0097176 16729 FUN_029088 0 0 76 0 40 NA NA NA NA NA NA NA 16730 FUN_032960 1341 1462 1028 1558 1442 ptg000023l:38130780-38137415 Q9D379 4.96e-60 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Mus musculus (Mouse) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; cellular aromatic compound metabolic process [GO:0006725]; cellular response to glucocorticoid stimulus [GO:0071385]; diol biosynthetic process [GO:0034312]; epoxide metabolic process [GO:0097176]; liver development [GO:0001889]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636] GO:0001889; GO:0004301; GO:0005789; GO:0005886; GO:0006725; GO:0009636; GO:0014070; GO:0016020; GO:0019369; GO:0019439; GO:0019899; GO:0033961; GO:0034312; GO:0043231; GO:0071385; GO:0097176 16731 FUN_032961 81 141 81 98 86 ptg000023l:38141181-38153021 Q9D379 5e-60 Epoxide hydrolase 1 (EC 3.3.2.9) (Epoxide hydratase) (Microsomal epoxide hydrolase) (mEH) Mus musculus (Mouse) arachidonic acid metabolic process [GO:0019369]; aromatic compound catabolic process [GO:0019439]; cellular aromatic compound metabolic process [GO:0006725]; cellular response to glucocorticoid stimulus [GO:0071385]; diol biosynthetic process [GO:0034312]; epoxide metabolic process [GO:0097176]; liver development [GO:0001889]; response to organic cyclic compound [GO:0014070]; response to toxic substance [GO:0009636] GO:0001889; GO:0004301; GO:0005789; GO:0005886; GO:0006725; GO:0009636; GO:0014070; GO:0016020; GO:0019369; GO:0019439; GO:0019899; GO:0033961; GO:0034312; GO:0043231; GO:0071385; GO:0097176 16732 FUN_029085 513 139 178 584 864 NA NA NA NA NA NA NA 16733 FUN_029084 2008 1651 924 1427 837 NA NA NA NA NA NA NA 16734 FUN_029087 0 0 0 0 23 NA NA NA NA NA NA NA 16735 FUN_029086 25 0 47 35 49 NA NA NA NA NA NA NA 16736 FUN_029081 105 31 120 76 22 NA NA NA NA NA NA NA 16737 FUN_043384 5722 3066 1964 4367 3696 NA NA NA NA NA NA NA 16738 FUN_016836 0 0 0 0 29 NA NA NA NA NA NA NA 16739 FUN_016834 0 0 0 0 42 ptg000011l:7938622-7954924 O70165 9.72e-41 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 16740 FUN_016838 0 0 0 0 15 NA NA NA NA NA NA NA 16741 FUN_008529 744 541 470 782 616 NA NA NA NA NA NA NA 16742 FUN_008528 17 0 0 14 20 NA NA NA NA NA NA NA 16743 FUN_008523 755 513 464 598 679 ptg000002l:12477714-12482930 B0X1Q4 8.21e-22 O-glucosyltransferase rumi homolog (EC 2.4.1.-) Culex quinquefasciatus (Southern house mosquito) (Culex pungens) protein O-linked glycosylation via serine [GO:0018242] GO:0005576; GO:0005788; GO:0018242; GO:0035251 16744 FUN_008523 755 513 464 598 679 ptg000002l:12477714-12482930 B0X1Q4 8.21e-22 O-glucosyltransferase rumi homolog (EC 2.4.1.-) Culex quinquefasciatus (Southern house mosquito) (Culex pungens) protein O-linked glycosylation via serine [GO:0018242] GO:0005576; GO:0005788; GO:0018242; GO:0035251 16745 FUN_008522 4672 2438 3216 3557 3291 NA NA NA NA NA NA NA 16746 FUN_008521 6503 4972 3704 4921 3073 NA NA NA NA NA NA NA 16747 FUN_008520 1192 927 424 580 1038 NA NA NA NA NA NA NA 16748 FUN_008527 38 0 0 0 28 NA NA NA NA NA NA NA 16749 FUN_008525 2051 853 894 2090 1742 ptg000002l:12490950-12524892 Q9P2N4 1.48e-21 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 16750 FUN_008525 2051 853 894 2090 1742 ptg000002l:12490950-12524892 Q9P2N4 1.48e-21 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 16751 FUN_008525 2051 853 894 2090 1742 ptg000002l:12490950-12524892 Q9P2N4 1.48e-21 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 16752 FUN_008525 2051 853 894 2090 1742 ptg000002l:12490950-12524892 Q9P2N4 1.48e-21 A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-) Homo sapiens (Human) aorta morphogenesis [GO:0035909]; endothelial cell-matrix adhesion [GO:0090673]; extracellular matrix organization [GO:0030198]; heart valve morphogenesis [GO:0003179]; melanocyte differentiation [GO:0030318]; negative regulation of endothelial cell migration [GO:0010596]; negative regulation of sprouting angiogenesis [GO:1903671]; positive regulation of melanocyte differentiation [GO:0045636]; protein transport [GO:0015031]; proteolysis [GO:0006508]; response to bacterium [GO:0009617]; ventricular cardiac muscle tissue development [GO:0003229]; vesicle-mediated transport [GO:0016192] GO:0003179; GO:0003229; GO:0004222; GO:0005615; GO:0005783; GO:0006508; GO:0008237; GO:0008270; GO:0009617; GO:0009986; GO:0010596; GO:0015031; GO:0016192; GO:0030198; GO:0030318; GO:0031012; GO:0035909; GO:0043231; GO:0045636; GO:0090673; GO:1903671 16753 FUN_008524 5276 4154 1969 3020 1458 ptg000002l:12483462-12487933 P20107 3.43e-30 Vacuolar zinc transporter ZRC1 (Zinc resistance conferring protein 1) (Zinc/cadmium resistance protein ZRC1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) cellular zinc ion homeostasis [GO:0006882]; response to cadmium ion [GO:0046686]; zinc ion transmembrane transport [GO:0071577] GO:0000324; GO:0000329; GO:0005385; GO:0006882; GO:0016020; GO:0046686; GO:0071577 16754 FUN_041986 1901 1238 1491 2828 2798 NA NA NA NA NA NA NA 16755 FUN_041987 822 811 529 1118 1140 NA NA NA NA NA NA NA 16756 FUN_041984 35 9 12 48 76 NA NA NA NA NA NA NA 16757 FUN_041985 69 128 112 346 365 NA NA NA NA NA NA NA 16758 FUN_041982 5 26 93 88 397 NA NA NA NA NA NA NA 16759 FUN_041983 0 0 0 7 17 NA NA NA NA NA NA NA 16760 FUN_041980 2802 1036 1055 1543 1059 NA NA NA NA NA NA NA 16761 FUN_041981 4197 5217 1880 2264 2861 NA NA NA NA NA NA NA 16762 FUN_041988 3360 2190 1627 3026 1961 NA NA NA NA NA NA NA 16763 FUN_041989 1708 1088 1235 1602 1694 NA NA NA NA NA NA NA 16764 FUN_004659 0 0 12 64 10 NA NA NA NA NA NA NA 16765 FUN_016785 0 0 0 0 9 NA NA NA NA NA NA NA 16766 FUN_016786 729 481 332 572 459 ptg000011l:7487750-7494373 Q7RTR2 9.31e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16767 FUN_016786 729 481 332 572 459 ptg000011l:7487750-7494373 Q7RTR2 1.96e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16768 FUN_016786 729 481 332 572 459 ptg000011l:7487750-7494373 Q7RTR2 2.06e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 16769 FUN_016787 713 443 214 299 320 NA NA NA NA NA NA NA 16770 FUN_016780 860 1634 639 800 745 NA NA NA NA NA NA NA 16771 FUN_012405 177 304 0 0 443 NA NA NA NA NA NA NA 16772 FUN_016782 6 3 2 1 10 NA NA NA NA NA NA NA 16773 FUN_016783 801 509 258 360 278 NA NA NA NA NA NA NA 16774 FUN_040053 3487 554 894 667 660 NA NA NA NA NA NA NA 16775 FUN_016789 0 0 0 1 14 NA NA NA NA NA NA NA 16776 FUN_040055 707 176 171 391 338 ptg000031l:3628904-3640153 P25291 4.29e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 16777 FUN_040055 707 176 171 391 338 ptg000031l:3628904-3640153 P25291 7.49e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 16778 FUN_040055 707 176 171 391 338 ptg000031l:3628904-3640153 P25291 4.18e-22 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 16779 FUN_003600 0 0 0 22 0 NA NA NA NA NA NA NA 16780 FUN_008555 354 179 68 141 101 NA NA NA NA NA NA NA 16781 FUN_006536 0 290 154 343 229 NA NA NA NA NA NA NA 16782 FUN_006537 115 122 200 356 316 NA NA NA NA NA NA NA 16783 FUN_034696 13 32 0 0 0 NA NA NA NA NA NA NA 16784 FUN_034697 65 65 26 2 0 NA NA NA NA NA NA NA 16785 FUN_034695 10 1 0 23 11 NA NA NA NA NA NA NA 16786 FUN_034692 25 5 0 867 34 NA NA NA NA NA NA NA 16787 FUN_034693 0 7 6 1481 50 NA NA NA NA NA NA NA 16788 FUN_034690 199 16 0 0 173 NA NA NA NA NA NA NA 16789 FUN_034691 0 0 0 0 35 NA NA NA NA NA NA NA 16790 FUN_008551 861 731 646 691 863 NA NA NA NA NA NA NA 16791 FUN_004126 3 0 0 4 27 NA NA NA NA NA NA NA 16792 FUN_016799 82 14 23 103 67 NA NA NA NA NA NA NA 16793 FUN_006851 4 0 1 1 82 NA NA NA NA NA NA NA 16794 FUN_016798 3234 2871 2027 4017 2776 ptg000011l:7649416-7688125 Q9P265 4.24e-30 Disco-interacting protein 2 homolog B (DIP2 homolog B) Homo sapiens (Human) negative regulation of axon extension [GO:0030517]; nervous system development [GO:0007399]; positive regulation of peptidyl-lysine acetylation [GO:2000758] GO:0005634; GO:0005737; GO:0007399; GO:0016020; GO:0030424; GO:0030425; GO:0030517; GO:0043014; GO:0043204; GO:0070062; GO:2000758 16795 FUN_006850 4342 3488 2260 2839 1737 NA NA NA NA NA NA NA 16796 FUN_016571 3723 3888 2122 4225 2616 ptg000011l:4882069-4895013 Q7ZU45 4.34e-27 Outer dynein arm-docking complex subunit 4 (Tetratricopeptide repeat protein 25) (TPR repeat protein 25) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005737; GO:0005856; GO:0032474; GO:0036158; GO:0042995; GO:0060271; GO:0061371 16797 FUN_016571 3723 3888 2122 4225 2616 ptg000011l:4882069-4895013 Q7ZU45 3.04e-25 Outer dynein arm-docking complex subunit 4 (Tetratricopeptide repeat protein 25) (TPR repeat protein 25) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of heart left/right asymmetry [GO:0061371]; otolith morphogenesis [GO:0032474]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0005737; GO:0005856; GO:0032474; GO:0036158; GO:0042995; GO:0060271; GO:0061371 16798 FUN_006852 49 66 62 68 35 NA NA NA NA NA NA NA 16799 FUN_006857 1741 721 638 1005 966 NA NA NA NA NA NA NA 16800 FUN_016574 2 0 6 2 13 NA NA NA NA NA NA NA 16801 FUN_042592 815 435 499 523 549 NA NA NA NA NA NA NA 16802 FUN_016797 94 62 77 48 33 ptg000011l:7643004-7647239 Q8TF09 9.27e-30 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0003777; GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0005929; GO:0007018; GO:0045505; GO:0097542 16803 FUN_042593 1956 929 995 1380 1476 ptg000039l:98549-105336 Q9HCJ5 0 Zinc finger SWIM domain-containing protein 6 Homo sapiens (Human) striatal medium spiny neuron differentiation [GO:0021773] GO:0008270; GO:0021773; GO:0031462 16804 FUN_042593 1956 929 995 1380 1476 ptg000039l:98549-105336 Q9HCJ5 1.4e-64 Zinc finger SWIM domain-containing protein 6 Homo sapiens (Human) striatal medium spiny neuron differentiation [GO:0021773] GO:0008270; GO:0021773; GO:0031462 16805 FUN_042593 1956 929 995 1380 1476 ptg000039l:98549-105336 Q9HCJ5 1.14e-34 Zinc finger SWIM domain-containing protein 6 Homo sapiens (Human) striatal medium spiny neuron differentiation [GO:0021773] GO:0008270; GO:0021773; GO:0031462 16806 FUN_016796 10707 8533 5988 12658 5351 NA NA NA NA NA NA NA 16807 FUN_023949 8001 7020 4444 10629 6506 ptg000018l:467807-473900 Q9DGG6 0 Adenylate cyclase type 9 (EC 4.6.1.1) (ATP pyrophosphate-lyase 9) (Adenylate cyclase type IX) (Adenylyl cyclase 9) Gallus gallus (Chicken) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cAMP biosynthetic process [GO:0006171]; intracellular signal transduction [GO:0035556] GO:0004016; GO:0005524; GO:0005886; GO:0006171; GO:0007189; GO:0016020; GO:0035556; GO:0046872; GO:0071880 16808 FUN_002558 105 114 145 311 175 NA NA NA NA NA NA NA 16809 FUN_002559 13 42 60 58 0 NA NA NA NA NA NA NA 16810 FUN_002554 23 206 221 321 200 NA NA NA NA NA NA NA 16811 FUN_003913 325 255 300 283 667 NA NA NA NA NA NA NA 16812 FUN_002556 235 0 7 233 3 NA NA NA NA NA NA NA 16813 FUN_002553 74 45 93 732 55 NA NA NA NA NA NA NA 16814 FUN_012208 0 0 0 10 0 NA NA NA NA NA NA NA 16815 FUN_012207 114 18 63 104 118 NA NA NA NA NA NA NA 16816 FUN_012201 5 32 17 14 7 NA NA NA NA NA NA NA 16817 FUN_012200 2 10 293 438 15 NA NA NA NA NA NA NA 16818 FUN_012203 5 0 9 4 7 NA NA NA NA NA NA NA 16819 FUN_013552 2722 2211 2216 4816 1650 ptg000008l:23974276-23990569 Q99570 7.81e-45 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16820 FUN_013552 2722 2211 2216 4816 1650 ptg000008l:23974276-23990569 Q99570 2.47e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16821 FUN_013553 1535 2265 1456 2145 1971 NA NA NA NA NA NA NA 16822 FUN_013550 119 279 528 165 155 NA NA NA NA NA NA NA 16823 FUN_013551 404 306 483 403 156 ptg000008l:23966703-23969714 P0C0R5 9.79e-30 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 16824 FUN_013556 4841 1521 918 18651 7049 NA NA NA NA NA NA NA 16825 FUN_040028 312 91 176 216 350 ptg000031l:3146246-3190383 Q8C1B2 6.82e-33 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16826 FUN_040028 312 91 176 216 350 ptg000031l:3146246-3190383 Q8C1B2 4.89e-28 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16827 FUN_013554 328 292 279 609 557 NA NA NA NA NA NA NA 16828 FUN_013555 61939 55025 44479 72773 59451 NA NA NA NA NA NA NA 16829 FUN_013558 108 126 113 22 45 NA NA NA NA NA NA NA 16830 FUN_040029 2048 2947 481 2217 603 ptg000031l:3196931-3247512 Q8C1B2 1.01e-42 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16831 FUN_040029 2048 2947 481 2217 603 ptg000031l:3196931-3247512 Q8C1B2 6.06e-41 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16832 FUN_040029 2048 2947 481 2217 603 ptg000031l:3196931-3247512 Q8C1B2 7.98e-37 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16833 FUN_040029 2048 2947 481 2217 603 ptg000031l:3196931-3247512 Q8C1B2 4.03e-36 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16834 FUN_004664 685 1900 885 1225 746 NA NA NA NA NA NA NA 16835 FUN_004666 1458 679 725 609 448 NA NA NA NA NA NA NA 16836 FUN_040025 0 0 37 74 0 ptg000031l:3112446-3123618 Q8C1B2 2.2e-35 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16837 FUN_040022 49 40 0 59 15 ptg000031l:3096010-3101894 Q8C1B2 1e-34 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 16838 FUN_031666 120 262 202 250 131 ptg000023l:24205467-24209571 P05419 1.37e-23 Neo-calmodulin (NeoCaM) Gallus gallus (Chicken) NA GO:0005509; GO:0030234 16839 FUN_004661 2210 777 1400 942 1386 NA NA NA NA NA NA NA 16840 FUN_031667 141 202 118 217 193 ptg000023l:24214276-24217687 P02594 1.28e-25 Calmodulin (CaM) Electrophorus electricus (Electric eel) (Gymnotus electricus) NA GO:0005509 16841 FUN_004662 94 37 4 82 112 NA NA NA NA NA NA NA 16842 FUN_004663 49 62 43 49 66 NA NA NA NA NA NA NA 16843 FUN_004128 259 383 320 310 405 NA NA NA NA NA NA NA 16844 FUN_017849 484 176 157 455 297 ptg000012l:1096632-1104039 O35910 9.15e-28 Monocarboxylate transporter 4 (MCT 4) (Monocarboxylate transporter 3) (MCT 3) (Solute carrier family 16 member 3) Rattus norvegicus (Rat) lactate transmembrane transport [GO:0035873]; monocarboxylic acid transport [GO:0015718]; plasma membrane lactate transport [GO:0035879]; protein catabolic process [GO:0030163]; pyruvate catabolic process [GO:0042867]; pyruvate transmembrane transport [GO:1901475] GO:0005886; GO:0008028; GO:0015129; GO:0015650; GO:0015718; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0030163; GO:0031965; GO:0035873; GO:0035879; GO:0042867; GO:0045202; GO:0050833; GO:0098688; GO:0098839; GO:1901475 16845 FUN_009609 0 34 0 0 0 NA NA NA NA NA NA NA 16846 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 4.06e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16847 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 8.89e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16848 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 3.89e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16849 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 9.28e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16850 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 2.63e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16851 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 1.36e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16852 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 1.45e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16853 FUN_009608 135 11 46 160 79 ptg000004l:9246480-9252073 Q80XJ3 1.72e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 16854 FUN_009605 0 0 0 11 0 NA NA NA NA NA NA NA 16855 FUN_009604 21 30 6 84 2 NA NA NA NA NA NA NA 16856 FUN_009607 39 5 0 49 35 NA NA NA NA NA NA NA 16857 FUN_009601 24 0 11 0 18 NA NA NA NA NA NA NA 16858 FUN_009603 34 8 5 749 191 ptg000004l:9190037-9193454 Q96AY4 1.2e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16859 FUN_009603 34 8 5 749 191 ptg000004l:9190037-9193454 Q96AY4 1.2e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16860 FUN_009603 34 8 5 749 191 ptg000004l:9190037-9193454 Q96AY4 4.89e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16861 FUN_009603 34 8 5 749 191 ptg000004l:9190037-9193454 Q96AY4 4.68e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16862 FUN_009602 15 0 2 0 4 NA NA NA NA NA NA NA 16863 FUN_029508 0 0 0 9 45 NA NA NA NA NA NA NA 16864 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 1.27e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16865 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 1.19e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16866 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 4.59e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16867 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 3.77e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16868 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 5.11e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16869 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 1.39e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16870 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 3.7e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16871 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 1.77e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16872 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 9.8e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16873 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 1.06e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16874 FUN_029509 1270 552 580 675 566 ptg000023l:2585645-2592292 Q96AY4 1.22e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16875 FUN_029501 0 0 0 22 0 NA NA NA NA NA NA NA 16876 FUN_029502 53 0 26 0 74 NA NA NA NA NA NA NA 16877 FUN_029505 0 0 26 0 75 NA NA NA NA NA NA NA 16878 FUN_029506 9 0 0 0 64 NA NA NA NA NA NA NA 16879 FUN_029507 11 0 0 0 0 NA NA NA NA NA NA NA 16880 FUN_017840 2361 2916 1375 2218 1842 NA NA NA NA NA NA NA 16881 FUN_017842 297 105 110 925 332 ptg000012l:1019975-1024192 Q29RY7 5.76e-27 Fibroleukin (Fibrinogen-like protein 2) Bos taurus (Bovine) negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0009986; GO:0016504; GO:0043381; GO:0050687; GO:0062023 16882 FUN_018893 0 0 67 20 0 NA NA NA NA NA NA NA 16883 FUN_018890 0 64 17 207 2 NA NA NA NA NA NA NA 16884 FUN_017847 42 14 16 0 12 NA NA NA NA NA NA NA 16885 FUN_003388 0 0 27 0 29 NA NA NA NA NA NA NA 16886 FUN_016006 312 166 91 388 35 NA NA NA NA NA NA NA 16887 FUN_042365 0 0 0 0 43 NA NA NA NA NA NA NA 16888 FUN_016004 1050 808 950 3610 1874 ptg000010l:355670-397908 Q9P2E3 6.26e-21 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 16889 FUN_016004 1050 808 950 3610 1874 ptg000010l:355670-397908 Q9P2E3 6.26e-21 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 16890 FUN_003382 51 0 0 24 72 NA NA NA NA NA NA NA 16891 FUN_003383 0 6 0 0 28 NA NA NA NA NA NA NA 16892 FUN_003380 2 11 39 0 107 NA NA NA NA NA NA NA 16893 FUN_003381 0 41 0 24 4 NA NA NA NA NA NA NA 16894 FUN_003386 20 0 1 1 29 NA NA NA NA NA NA NA 16895 FUN_003387 5 67 6 0 30 NA NA NA NA NA NA NA 16896 FUN_003384 393 320 321 374 403 NA NA NA NA NA NA NA 16897 FUN_008952 7290 3924 3684 5763 4899 NA NA NA NA NA NA NA 16898 FUN_008953 12000 8989 6656 13366 7975 NA NA NA NA NA NA NA 16899 FUN_008950 1675 1409 1322 1823 1407 ptg000004l:733618-742143 Q5XI65 1.12e-23 Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) Rattus norvegicus (Rat) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; regulation of cilium movement [GO:0003352] GO:0003352; GO:0005829; GO:0005858; GO:0005930; GO:0007368; GO:0007507; GO:0031514; GO:0060285; GO:0070286 16900 FUN_008950 1675 1409 1322 1823 1407 ptg000004l:733618-742143 Q5XI65 1.12e-23 Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) Rattus norvegicus (Rat) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; regulation of cilium movement [GO:0003352] GO:0003352; GO:0005829; GO:0005858; GO:0005930; GO:0007368; GO:0007507; GO:0031514; GO:0060285; GO:0070286 16901 FUN_008950 1675 1409 1322 1823 1407 ptg000004l:733618-742143 Q5XI65 1.12e-23 Dynein regulatory complex protein 1 (Coiled-coil domain-containing protein 164) Rattus norvegicus (Rat) axonemal dynein complex assembly [GO:0070286]; cilium-dependent cell motility [GO:0060285]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; regulation of cilium movement [GO:0003352] GO:0003352; GO:0005829; GO:0005858; GO:0005930; GO:0007368; GO:0007507; GO:0031514; GO:0060285; GO:0070286 16902 FUN_008951 1913 1489 1772 1675 1600 ptg000004l:742527-745841 Q6IRP4 4.77e-37 Protein ABHD13 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 13) (Abhydrolase domain-containing protein 13) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0016787 16903 FUN_008956 4813 4910 2683 6420 4062 ptg000004l:820473-823699 Q2VJ60 3.58e-96 E3 ubiquitin-protein ligase RNF19A (EC 2.3.2.31) (Double ring-finger protein) (Dorfin) (RING finger protein 19A) Sus scrofa (Pig) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; regulation of protein catabolic process at postsynapse, modulating synaptic transmission [GO:0099576]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0005737; GO:0005815; GO:0006511; GO:0016020; GO:0031624; GO:0032436; GO:0046872; GO:0061630; GO:0098686; GO:0098794; GO:0098978; GO:0099576 16904 FUN_008957 1712 1457 1204 1406 482 NA NA NA NA NA NA NA 16905 FUN_008954 1243 1209 777 1247 1785 NA NA NA NA NA NA NA 16906 FUN_008955 2783 853 1122 2121 2294 ptg000004l:801976-818002 Q7TPQ3 7.98e-23 E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000786; GO:0003677; GO:0004386; GO:0004842; GO:0005524; GO:0005634; GO:0006281; GO:0006334; GO:0006974; GO:0016787; GO:0031625; GO:0046872; GO:0061630; GO:0140658 16907 FUN_008955 2783 853 1122 2121 2294 ptg000004l:801976-818002 Q7TPQ3 7.98e-23 E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; nucleosome assembly [GO:0006334]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0000786; GO:0003677; GO:0004386; GO:0004842; GO:0005524; GO:0005634; GO:0006281; GO:0006334; GO:0006974; GO:0016787; GO:0031625; GO:0046872; GO:0061630; GO:0140658 16908 FUN_008958 54376 109295 94610 26807 67586 NA NA NA NA NA NA NA 16909 FUN_008959 1118 929 643 694 921 NA NA NA NA NA NA NA 16910 FUN_028679 47 12 7 8 34 ptg000022l:2584942-2594744 Q96AY4 1.43e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16911 FUN_028679 47 12 7 8 34 ptg000022l:2584942-2594744 Q96AY4 5.94e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16912 FUN_028679 47 12 7 8 34 ptg000022l:2584942-2594744 Q96AY4 2.13e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16913 FUN_028679 47 12 7 8 34 ptg000022l:2584942-2594744 Q96AY4 3.18e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 16914 FUN_028678 2 4 2 11 12 NA NA NA NA NA NA NA 16915 FUN_026219 180 325 105 0 206 NA NA NA NA NA NA NA 16916 FUN_026218 33 0 7 0 14 NA NA NA NA NA NA NA 16917 FUN_026215 1254 622 496 3279 548 ptg000020l:6200731-6210941 P16157 8.27e-44 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16918 FUN_026215 1254 622 496 3279 548 ptg000020l:6200731-6210941 P16157 1.05e-40 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16919 FUN_026215 1254 622 496 3279 548 ptg000020l:6200731-6210941 P16157 2.29e-35 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16920 FUN_026215 1254 622 496 3279 548 ptg000020l:6200731-6210941 P16157 2.89e-30 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16921 FUN_026214 537 450 1071 1522 3912 NA NA NA NA NA NA NA 16922 FUN_026217 50 31 44 771 54 ptg000020l:6242557-6244756 P16157 1.25e-63 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16923 FUN_026217 50 31 44 771 54 ptg000020l:6242557-6244756 P16157 4.57e-61 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16924 FUN_026217 50 31 44 771 54 ptg000020l:6242557-6244756 P16157 3.76e-60 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16925 FUN_026217 50 31 44 771 54 ptg000020l:6242557-6244756 P16157 2.88e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16926 FUN_026217 50 31 44 771 54 ptg000020l:6242557-6244756 P16157 6.13e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16927 FUN_026217 50 31 44 771 54 ptg000020l:6242557-6244756 P16157 2e-43 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 16928 FUN_026216 521 187 197 252 392 NA NA NA NA NA NA NA 16929 FUN_028674 9 0 0 0 0 NA NA NA NA NA NA NA 16930 FUN_028677 18 18 10 10 46 NA NA NA NA NA NA NA 16931 FUN_026212 2423 1031 950 4796 3582 NA NA NA NA NA NA NA 16932 FUN_025742 207 235 240 381 151 NA NA NA NA NA NA NA 16933 FUN_025741 2248 5291 2921 2831 1342 NA NA NA NA NA NA NA 16934 FUN_025746 10983 14099 9748 22840 13740 ptg000020l:328493-332791 Q6P132 7.03e-37 Tax1-binding protein 1 homolog B Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic process [GO:0006915] GO:0006915; GO:0046872 16935 FUN_025747 14501 17191 8094 15831 6288 ptg000020l:337988-342681 Q80ZQ5 1.81e-31 Juxtaposed with another zinc finger protein 1 Mus musculus (Mouse) lipid metabolic process [GO:0006629]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0001650; GO:0003714; GO:0005634; GO:0005654; GO:0005829; GO:0006629; GO:0017053; GO:0046872 16936 FUN_025744 198 2114 2055 257 492 ptg000020l:294329-312378 P21328 2.47e-27 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 16937 FUN_025745 604 290 228 512 937 ptg000020l:315566-324306 Q86XL3 8.1e-22 Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4) Homo sapiens (Human) cell division [GO:0051301]; central nervous system development [GO:0007417]; mitotic nuclear membrane reassembly [GO:0007084]; negative regulation of apoptotic process [GO:0043066]; negative regulation of phosphorylation [GO:0042326]; positive regulation of protein dephosphorylation [GO:0035307]; regulation of catalytic activity [GO:0050790] GO:0005783; GO:0005789; GO:0007084; GO:0007417; GO:0016020; GO:0019888; GO:0035307; GO:0042326; GO:0043066; GO:0050790; GO:0051301; GO:0051721 16938 FUN_025748 3381 3425 2367 3906 2421 ptg000020l:342979-347875 Q6PCF7 1.49e-28 Ubiquitin-conjugating enzyme E2 Z (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Z) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915] GO:0005524; GO:0005634; GO:0005737; GO:0006915; GO:0061631 16939 FUN_025749 348 191 278 216 311 NA NA NA NA NA NA NA 16940 FUN_023591 2988 2086 1842 3971 3006 ptg000017l:9637425-9646983 A7Z035 2.24e-25 Clathrin interactor 1 (Epsin-4) Bos taurus (Bovine) endocytosis [GO:0006897] GO:0005543; GO:0005654; GO:0005768; GO:0005798; GO:0005802; GO:0005886; GO:0006897; GO:0030125; GO:0030276; GO:0048471 16941 FUN_023590 561 539 393 407 500 NA NA NA NA NA NA NA 16942 FUN_023593 886 295 375 494 538 NA NA NA NA NA NA NA 16943 FUN_023592 4342 2290 1305 2798 2826 NA NA NA NA NA NA NA 16944 FUN_023595 39 38 42 101 35 NA NA NA NA NA NA NA 16945 FUN_023594 2067 2321 1455 1944 1850 ptg000017l:9692022-9694696 Q9CQ52 1.99e-24 Chymotrypsin-like elastase family member 3B (EC 3.4.21.70) (Elastase IIIB) (Elastase-3B) (Protease E) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0062023 16946 FUN_023597 658 610 604 777 786 ptg000017l:9704034-9704776 P80646 6.22e-27 Chymotrypsin B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B] Gadus morhua (Atlantic cod) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 16947 FUN_023597 658 610 604 777 786 ptg000017l:9704034-9704776 P80646 6.22e-27 Chymotrypsin B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B] Gadus morhua (Atlantic cod) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 16948 FUN_023596 1411 2347 1222 2394 1230 ptg000017l:9699993-9702655 Q9Y5Y6 6.15e-24 Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein) Homo sapiens (Human) epithelial cell morphogenesis involved in placental branching [GO:0060672]; keratinocyte differentiation [GO:0030216]; neural tube closure [GO:0001843]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0001843; GO:0004252; GO:0005615; GO:0005886; GO:0006508; GO:0008236; GO:0009897; GO:0016323; GO:0030163; GO:0030216; GO:0060672 16949 FUN_023599 0 0 18 0 30 ptg000017l:9723971-9726380 Q640T1 2.48e-25 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 16950 FUN_023598 403 406 338 473 486 ptg000017l:9708978-9718156 Q640T1 7.44e-25 Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) allantoin catabolic process [GO:0000256]; purine nucleobase metabolic process [GO:0006144] GO:0000256; GO:0004037; GO:0006144 16951 FUN_022246 0 5 24 40 9 NA NA NA NA NA NA NA 16952 FUN_022247 594 181 233 441 205 NA NA NA NA NA NA NA 16953 FUN_022244 2456 2983 1921 1382 927 NA NA NA NA NA NA NA 16954 FUN_022245 816 364 476 782 1026 NA NA NA NA NA NA NA 16955 FUN_022242 3224 2089 1991 2476 1941 NA NA NA NA NA NA NA 16956 FUN_025291 74 0 0 0 21 NA NA NA NA NA NA NA 16957 FUN_025292 52 8 0 20 20 NA NA NA NA NA NA NA 16958 FUN_022241 847 455 670 788 822 NA NA NA NA NA NA NA 16959 FUN_025298 51 34 19 332 4 NA NA NA NA NA NA NA 16960 FUN_028163 341 170 80 231 308 NA NA NA NA NA NA NA 16961 FUN_022248 557 1007 866 404 404 NA NA NA NA NA NA NA 16962 FUN_022249 2153 1330 1181 2130 1555 NA NA NA NA NA NA NA 16963 FUN_011848 1083 904 686 2324 1811 NA NA NA NA NA NA NA 16964 FUN_011849 257 214 238 391 187 NA NA NA NA NA NA NA 16965 FUN_011842 1025 704 599 1313 869 NA NA NA NA NA NA NA 16966 FUN_011840 209 316 271 154 316 NA NA NA NA NA NA NA 16967 FUN_011841 4129 6648 2644 4161 1791 NA NA NA NA NA NA NA 16968 FUN_011846 2529 1764 1216 1613 1002 NA NA NA NA NA NA NA 16969 FUN_011847 2012 1969 808 1801 1483 NA NA NA NA NA NA NA 16970 FUN_011844 3748 2437 2097 3140 2877 ptg000008l:2035045-2039296 Q9UPY6 4.69e-25 Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; actin filament polymerization [GO:0030041]; cytoskeleton organization [GO:0007010]; lamellipodium assembly [GO:0030032]; modification of postsynaptic actin cytoskeleton [GO:0098885]; oligodendrocyte development [GO:0014003]; positive regulation of Arp2/3 complex-mediated actin nucleation [GO:2000601]; positive regulation of myelination [GO:0031643]; protein-containing complex assembly [GO:0065003]; regulation of cell shape [GO:0008360] GO:0003779; GO:0005856; GO:0007010; GO:0008360; GO:0014003; GO:0030027; GO:0030032; GO:0030036; GO:0030041; GO:0031209; GO:0031643; GO:0034237; GO:0065003; GO:0070062; GO:0071933; GO:0097386; GO:0098794; GO:0098885; GO:0098978; GO:2000601 16971 FUN_028164 1423 989 321 483 272 NA NA NA NA NA NA NA 16972 FUN_044030 91 481 1229 324 629 NA NA NA NA NA NA NA 16973 FUN_019544 0 0 0 0 19 NA NA NA NA NA NA NA 16974 FUN_044035 170 467 702 242 208 NA NA NA NA NA NA NA 16975 FUN_014314 0 0 0 21 10 NA NA NA NA NA NA NA 16976 FUN_044036 637 6384 10911 4263 3534 NA NA NA NA NA NA NA 16977 FUN_044039 637 6525 11565 4315 3709 NA NA NA NA NA NA NA 16978 FUN_019549 0 0 7 9 9 NA NA NA NA NA NA NA 16979 FUN_019548 0 4 140 12 257 NA NA NA NA NA NA NA 16980 FUN_018033 3237 1427 1176 1995 2402 NA NA NA NA NA NA NA 16981 FUN_024165 129 86 89 66 67 NA NA NA NA NA NA NA 16982 FUN_024164 19 11 0 0 0 NA NA NA NA NA NA NA 16983 FUN_024167 0 9 6 0 13 NA NA NA NA NA NA NA 16984 FUN_024166 92 124 37 96 46 NA NA NA NA NA NA NA 16985 FUN_024161 59 10 15 18 98 NA NA NA NA NA NA NA 16986 FUN_024160 12748 8105 4497 12406 5453 NA NA NA NA NA NA NA 16987 FUN_024163 4322 2168 1949 3751 2743 NA NA NA NA NA NA NA 16988 FUN_024162 79 81 58 187 95 ptg000018l:2921110-2921863 Q20201 2.24e-22 Transcription factor sox-3 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0030182; GO:0043565 16989 FUN_024169 87 37 54 20 90 NA NA NA NA NA NA NA 16990 FUN_024168 160 270 233 114 93 NA NA NA NA NA NA NA 16991 FUN_009407 128 0 72 118 228 NA NA NA NA NA NA NA 16992 FUN_023314 49 47 67 93 136 NA NA NA NA NA NA NA 16993 FUN_037408 415 518 241 301 499 NA NA NA NA NA NA NA 16994 FUN_037409 1242 847 725 1286 1570 NA NA NA NA NA NA NA 16995 FUN_037406 99 166 301 117 174 NA NA NA NA NA NA NA 16996 FUN_037407 51 10 4 9 55 NA NA NA NA NA NA NA 16997 FUN_037404 409 156 209 389 504 NA NA NA NA NA NA NA 16998 FUN_037405 61 15 36 88 54 NA NA NA NA NA NA NA 16999 FUN_037402 848 348 739 981 1215 NA NA NA NA NA NA NA 17000 FUN_037403 13 0 0 57 54 NA NA NA NA NA NA NA 17001 FUN_037400 290 471 124 148 134 NA NA NA NA NA NA NA 17002 FUN_037401 1285 637 1612 1136 960 ptg000026l:9940229-9942398 Q9SZJ2 2.99e-29 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 17003 FUN_005728 14 0 0 57 17 NA NA NA NA NA NA NA 17004 FUN_005729 26 9 4 12 25 NA NA NA NA NA NA NA 17005 FUN_005727 0 0 0 0 9 NA NA NA NA NA NA NA 17006 FUN_005724 890 695 318 724 776 NA NA NA NA NA NA NA 17007 FUN_005725 1973 1099 885 1704 2408 ptg000001l:3207766-3261322 O60290 9.14e-31 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 17008 FUN_005722 243 83 47 212 221 ptg000001l:3134645-3135773 Q08DG4 1.06e-27 F-box/LRR-repeat protein 8 (F-box and leucine-rich repeat protein 8) Bos taurus (Bovine) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005634; GO:0005829; GO:0019005; GO:0031146; GO:0043153; GO:0051726 17009 FUN_005720 285 161 136 115 189 ptg000001l:3056632-3125058 Q7LHG5 6.83e-66 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17010 FUN_005720 285 161 136 115 189 ptg000001l:3056632-3125058 Q7LHG5 6.83e-66 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17011 FUN_005720 285 161 136 115 189 ptg000001l:3056632-3125058 Q7LHG5 6.83e-66 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17012 FUN_005720 285 161 136 115 189 ptg000001l:3056632-3125058 Q7LHG5 7.77e-49 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17013 FUN_005720 285 161 136 115 189 ptg000001l:3056632-3125058 Q7LHG5 3.08e-42 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17014 FUN_005720 285 161 136 115 189 ptg000001l:3056632-3125058 Q7LHG5 3.08e-42 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17015 FUN_001438 8 11 0 1 5 NA NA NA NA NA NA NA 17016 FUN_001439 8 122 0 0 43 ntLink_6:12432040-12434625 P58912 1.14e-82 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17017 FUN_001436 0 26 0 0 0 NA NA NA NA NA NA NA 17018 FUN_001437 20 6 0 0 0 ntLink_6:12424679-12426218 P58912 2.99e-66 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17019 FUN_001434 18 27 0 0 0 ntLink_6:12412159-12413929 P58912 1.73e-71 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17020 FUN_001435 0 31 0 0 0 ntLink_6:12414004-12417799 P58912 8.84e-30 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17021 FUN_001432 0 14 0 0 2 ntLink_6:12398132-12399902 Q76DT2 4.75e-62 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17022 FUN_001433 0 16 4 0 48 ntLink_6:12401696-12403334 P58912 3.06e-86 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17023 FUN_001430 3 29 114 3 198 ntLink_6:12389727-12391206 P58912 1.96e-84 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 17024 FUN_001431 7 0 0 0 0 NA NA NA NA NA NA NA 17025 FUN_037548 590 228 395 397 643 NA NA NA NA NA NA NA 17026 FUN_026158 929 955 404 1015 812 NA NA NA NA NA NA NA 17027 FUN_026159 669 118 722 657 662 ptg000020l:5371127-5385224 Q8N0W4 8.8e-59 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 17028 FUN_026159 669 118 722 657 662 ptg000020l:5371127-5385224 Q8N0W4 7.04e-57 Neuroligin-4, X-linked (Neuroligin X) (HNLX) Homo sapiens (Human) adult behavior [GO:0030534]; brainstem development [GO:0003360]; cell-cell junction organization [GO:0045216]; cerebellum development [GO:0021549]; chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of excitatory postsynaptic potential [GO:0090394]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; organ growth [GO:0035265]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synapse organization [GO:0050808]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0003360; GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0021549; GO:0030182; GO:0030425; GO:0030534; GO:0031404; GO:0035176; GO:0035265; GO:0038023; GO:0042043; GO:0042803; GO:0045202; GO:0045216; GO:0048488; GO:0050804; GO:0050808; GO:0050839; GO:0060076; GO:0071625; GO:0090394; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 17029 FUN_026150 796 135 304 448 854 NA NA NA NA NA NA NA 17030 FUN_026151 338 110 82 143 217 ptg000020l:5327006-5328110 Q9SE95 1.29e-27 FH protein interacting protein FIP2 (BTB/POZ domain-containing protein At5g55000) Arabidopsis thaliana (Mouse-ear cress) protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567] GO:0016567; GO:0051260 17031 FUN_026156 6465 5906 3892 8637 7179 NA NA NA NA NA NA NA 17032 FUN_026157 95 6 89 109 167 NA NA NA NA NA NA NA 17033 FUN_026154 717 683 311 481 277 NA NA NA NA NA NA NA 17034 FUN_026155 9134 5264 2898 5985 4072 NA NA NA NA NA NA NA 17035 FUN_001380 137 101 19 67 320 NA NA NA NA NA NA NA 17036 FUN_043650 344 321 206 739 362 NA NA NA NA NA NA NA 17037 FUN_001383 328 237 280 347 249 ntLink_6:11808568-11819005 Q64077 5.36e-24 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Cavia porcellus (Guinea pig) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 17038 FUN_001384 839 516 597 1527 2078 NA NA NA NA NA NA NA 17039 FUN_001385 3810 3225 2274 3777 4543 NA NA NA NA NA NA NA 17040 FUN_001386 18214 15167 9842 14459 11208 ntLink_6:11837002-11843219 P63696 4.08e-40 Uncharacterized transporter Mb0941 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) nitrogen compound transport [GO:0071705] GO:0005886; GO:0022857; GO:0071705 17041 FUN_001387 119 67 151 59 263 ntLink_6:11848247-11849207 Q8BZL4 5.88e-26 G-protein coupled receptor 22 Mus musculus (Mouse) cell projection organization [GO:0030030]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186; GO:0030030; GO:0042277 17042 FUN_001388 1056 607 707 911 792 NA NA NA NA NA NA NA 17043 FUN_001389 192 1719 38 177 128 NA NA NA NA NA NA NA 17044 FUN_010807 15427 10056 5468 9533 3846 ptg000007l:3014667-3038015 Q9VP61 3.21e-23 Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-activating enzyme) Drosophila melanogaster (Fruit fly) acetyl-CoA biosynthetic process [GO:0006085]; acetyl-CoA biosynthetic process from acetate [GO:0019427]; behavioral response to ethanol [GO:0048149]; fatty acid biosynthetic process [GO:0006633]; photoreceptor cell maintenance [GO:0045494] GO:0003987; GO:0005524; GO:0005737; GO:0006085; GO:0006633; GO:0016208; GO:0019427; GO:0031955; GO:0045494; GO:0048149 17045 FUN_010801 85 37 89 75 151 NA NA NA NA NA NA NA 17046 FUN_002544 32 460 201 1659 277 NA NA NA NA NA NA NA 17047 FUN_019029 700 236 138 0 73 NA NA NA NA NA NA NA 17048 FUN_010803 584 355 311 530 517 NA NA NA NA NA NA NA 17049 FUN_037544 1775 1242 1104 1081 1384 NA NA NA NA NA NA NA 17050 FUN_004099 13053 12185 7989 14253 14908 NA NA NA NA NA NA NA 17051 FUN_004098 919 872 761 855 762 NA NA NA NA NA NA NA 17052 FUN_004097 270 122 123 166 236 NA NA NA NA NA NA NA 17053 FUN_004096 43 110 55 83 96 ntLink_8:19243170-19248026 Q9NQX0 7.27e-42 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 17054 FUN_004096 43 110 55 83 96 ntLink_8:19243170-19248026 Q9NQX0 7.27e-42 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 17055 FUN_004095 1180 318 421 737 613 NA NA NA NA NA NA NA 17056 FUN_004094 52379 14858 13982 73313 56731 NA NA NA NA NA NA NA 17057 FUN_004093 213 192 84 194 275 ntLink_8:19194501-19197203 O60235 5.01e-32 Transmembrane protease serine 11D (EC 3.4.21.-) (Airway trypsin-like protease) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain] Homo sapiens (Human) proteolysis [GO:0006508]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0007585; GO:0008233; GO:0070062 17058 FUN_004092 1073 1100 502 925 899 NA NA NA NA NA NA NA 17059 FUN_004091 2501 797 1245 435 517 ntLink_8:19156550-19169189 Q9JHA8 1.41e-25 von Willebrand factor A domain-containing protein 7 (Protein G7c) Mus musculus (Mouse) NA GO:0005576 17060 FUN_004090 614 9 69 160 30 ntLink_8:19127929-19142564 Q9JHA8 2.43e-27 von Willebrand factor A domain-containing protein 7 (Protein G7c) Mus musculus (Mouse) NA GO:0005576 17061 FUN_018085 218 100 571 1018 534 NA NA NA NA NA NA NA 17062 FUN_018087 678 716 644 690 640 NA NA NA NA NA NA NA 17063 FUN_018086 1712 683 489 1416 1481 ptg000012l:4129842-4244245 P14381 1.33e-87 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 17064 FUN_018086 1712 683 489 1416 1481 ptg000012l:4129842-4244245 P14381 1.33e-87 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 17065 FUN_018080 0 256 29 98 27 NA NA NA NA NA NA NA 17066 FUN_018083 629 7404 2402 58 922 NA NA NA NA NA NA NA 17067 FUN_018082 46 332 337 99 217 NA NA NA NA NA NA NA 17068 FUN_018089 2860 1970 1818 1983 1408 NA NA NA NA NA NA NA 17069 FUN_018088 99 111 65 107 67 NA NA NA NA NA NA NA 17070 FUN_041762 1984 1627 1000 1781 1553 NA NA NA NA NA NA NA 17071 FUN_041763 519 271 313 579 402 NA NA NA NA NA NA NA 17072 FUN_041760 2549 2354 1033 1319 1072 ptg000035l:7214905-7217131 A6H7H7 3.32e-52 F-box only protein 3 Bos taurus (Bovine) response to lipopolysaccharide [GO:0032496]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005654; GO:0005737; GO:0005829; GO:0019005; GO:0031146; GO:0032496; GO:1990756 17073 FUN_033895 95 25 19 82 191 NA NA NA NA NA NA NA 17074 FUN_033894 554 273 350 516 1965 NA NA NA NA NA NA NA 17075 FUN_033896 0 0 21 34 58 NA NA NA NA NA NA NA 17076 FUN_033891 461 387 226 621 382 NA NA NA NA NA NA NA 17077 FUN_033890 3372 2906 1438 3538 2252 NA NA NA NA NA NA NA 17078 FUN_033893 959 382 836 1066 864 NA NA NA NA NA NA NA 17079 FUN_033892 658 565 387 908 788 NA NA NA NA NA NA NA 17080 FUN_000332 0 0 0 16 5 NA NA NA NA NA NA NA 17081 FUN_031945 1494 709 220 449 1088 NA NA NA NA NA NA NA 17082 FUN_031944 1967 2972 1182 1099 1247 NA NA NA NA NA NA NA 17083 FUN_031947 18 59 18 72 31 NA NA NA NA NA NA NA 17084 FUN_031941 71 25 23 51 0 NA NA NA NA NA NA NA 17085 FUN_031940 160 126 145 90 136 NA NA NA NA NA NA NA 17086 FUN_034329 1064 1066 391 708 511 NA NA NA NA NA NA NA 17087 FUN_018337 0 0 31 15 1 NA NA NA NA NA NA NA 17088 FUN_044255 3 2 6 5 7 NA NA NA NA NA NA NA 17089 FUN_018334 70 0 54 177 42 NA NA NA NA NA NA NA 17090 FUN_018333 228 249 124 136 102 ptg000012l:7759056-7815727 Q9NBX4 3.51e-23 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 17091 FUN_034323 1761 493 700 2626 982 NA NA NA NA NA NA NA 17092 FUN_018331 12 0 0 0 19 NA NA NA NA NA NA NA 17093 FUN_034321 407 113 200 391 293 ptg000024l:7603189-7606948 Q6GNV7 1.74e-38 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 17094 FUN_035330 0 0 10 0 0 NA NA NA NA NA NA NA 17095 FUN_035331 7605 2024 2411 2794 1491 NA NA NA NA NA NA NA 17096 FUN_005473 963 964 1022 1086 1171 NA NA NA NA NA NA NA 17097 FUN_013544 502 1954 1232 968 152 ptg000008l:23898662-23909640 Q7RTR2 1.11e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17098 FUN_013544 502 1954 1232 968 152 ptg000008l:23898662-23909640 Q7RTR2 1.21e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17099 FUN_013544 502 1954 1232 968 152 ptg000008l:23898662-23909640 Q7RTR2 2.63e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17100 FUN_013544 502 1954 1232 968 152 ptg000008l:23898662-23909640 Q7RTR2 1.24e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17101 FUN_001933 117 46 123 322 179 NA NA NA NA NA NA NA 17102 FUN_036686 2 0 9 0 12 NA NA NA NA NA NA NA 17103 FUN_039981 4154 3794 2455 5790 3243 NA NA NA NA NA NA NA 17104 FUN_039980 1720 1510 859 1723 742 NA NA NA NA NA NA NA 17105 FUN_001934 6 0 6 0 7 NA NA NA NA NA NA NA 17106 FUN_033927 96 126 61 147 162 NA NA NA NA NA NA NA 17107 FUN_007016 3353 3230 1819 2709 3322 ptg000001l:19337954-19348318 Q68FX0 5.19e-32 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (Isocitric dehydrogenase subunit beta) (NAD(+)-specific ICDH subunit beta) Rattus norvegicus (Rat) 2-oxoglutarate metabolic process [GO:0006103]; isocitrate metabolic process [GO:0006102]; NADH metabolic process [GO:0006734]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004449; GO:0005739; GO:0005962; GO:0006099; GO:0006102; GO:0006103; GO:0006734; GO:0051287 17108 FUN_007017 132 82 44 112 229 ptg000001l:19349312-19349858 Q3SX07 1.51e-33 tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) Bos taurus (Bovine) mRNA pseudouridine synthesis [GO:1990481]; tRNA pseudouridine synthesis [GO:0031119] GO:0003723; GO:0005634; GO:0005737; GO:0009982; GO:0031119; GO:0106029; GO:1990481 17109 FUN_007014 734 114 273 374 174 NA NA NA NA NA NA NA 17110 FUN_033926 640 470 225 620 318 NA NA NA NA NA NA NA 17111 FUN_043214 272 227 69 283 187 NA NA NA NA NA NA NA 17112 FUN_043215 106 31 6 237 37 NA NA NA NA NA NA NA 17113 FUN_043216 39 45 0 37 0 NA NA NA NA NA NA NA 17114 FUN_007011 120 63 45 90 123 NA NA NA NA NA NA NA 17115 FUN_043218 8684 7681 8113 7124 8185 NA NA NA NA NA NA NA 17116 FUN_039985 30 0 0 0 44 NA NA NA NA NA NA NA 17117 FUN_007018 695 885 256 732 698 ptg000001l:19350168-19351810 Q3SX07 5.13e-74 tRNA pseudouridine(38/39) synthase (EC 5.4.99.45) (tRNA pseudouridine synthase 3) (tRNA pseudouridylate synthase 3) (tRNA-uridine isomerase 3) Bos taurus (Bovine) mRNA pseudouridine synthesis [GO:1990481]; tRNA pseudouridine synthesis [GO:0031119] GO:0003723; GO:0005634; GO:0005737; GO:0009982; GO:0031119; GO:0106029; GO:1990481 17118 FUN_007019 649 255 399 738 512 ptg000001l:19355226-19365828 Q4PZA2 5.12e-23 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Mus musculus (Mouse) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to hypoxia [GO:0001666]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009897; GO:0009986; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 17119 FUN_019068 0 0 0 0 40 NA NA NA NA NA NA NA 17120 FUN_033923 1649 1344 1090 1943 2465 NA NA NA NA NA NA NA 17121 FUN_019065 0 0 0 34 14 NA NA NA NA NA NA NA 17122 FUN_039986 29 110 64 44 58 NA NA NA NA NA NA NA 17123 FUN_019060 0 0 0 0 13 NA NA NA NA NA NA NA 17124 FUN_019061 38 0 32 15 65 NA NA NA NA NA NA NA 17125 FUN_019063 0 0 9 0 7 NA NA NA NA NA NA NA 17126 FUN_018860 2346 725 1064 2054 1398 NA NA NA NA NA NA NA 17127 FUN_034818 1076 1148 244 956 1173 ptg000025l:397798-398134 P47773 2.3e-60 Heat shock cognate 71 kDa protein Ictalurus punctatus (Channel catfish) (Silurus punctatus) NA GO:0005524; GO:0140662 17128 FUN_034819 1037 1401 1665 738 730 NA NA NA NA NA NA NA 17129 FUN_034814 1655 2064 1625 3418 3533 NA NA NA NA NA NA NA 17130 FUN_034815 3873 5433 3204 4460 3118 ptg000025l:369247-387506 P10394 4.14e-113 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 17131 FUN_034816 191 532 263 242 72 NA NA NA NA NA NA NA 17132 FUN_034817 9995 7564 5928 9066 6376 NA NA NA NA NA NA NA 17133 FUN_034810 125 72 43 254 296 ptg000025l:352400-353817 B8ARK7 7.51e-51 NAD-dependent protein deacetylase SRT1 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (OsSIRT1) Oryza sativa subsp. indica (Rice) ethylene-activated signaling pathway [GO:0009873]; histone H3-K9 acetylation [GO:0043970] GO:0005634; GO:0009873; GO:0016740; GO:0031490; GO:0033558; GO:0043970; GO:0046872; GO:0070403 17134 FUN_034810 125 72 43 254 296 ptg000025l:352400-353817 B8ARK7 7.51e-51 NAD-dependent protein deacetylase SRT1 (EC 2.3.1.286) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (OsSIRT1) Oryza sativa subsp. indica (Rice) ethylene-activated signaling pathway [GO:0009873]; histone H3-K9 acetylation [GO:0043970] GO:0005634; GO:0009873; GO:0016740; GO:0031490; GO:0033558; GO:0043970; GO:0046872; GO:0070403 17135 FUN_034811 937 473 288 367 304 ptg000025l:354588-358701 Q3SYZ6 4.18e-74 Xylulose kinase (Xylulokinase) (EC 2.7.1.17) Bos taurus (Bovine) D-xylose metabolic process [GO:0042732]; phosphorylation [GO:0016310]; xylulose metabolic process [GO:0005997] GO:0004856; GO:0005524; GO:0005829; GO:0005997; GO:0016310; GO:0016773; GO:0042732 17136 FUN_034811 937 473 288 367 304 ptg000025l:354588-358701 Q3SYZ6 2.98e-37 Xylulose kinase (Xylulokinase) (EC 2.7.1.17) Bos taurus (Bovine) D-xylose metabolic process [GO:0042732]; phosphorylation [GO:0016310]; xylulose metabolic process [GO:0005997] GO:0004856; GO:0005524; GO:0005829; GO:0005997; GO:0016310; GO:0016773; GO:0042732 17137 FUN_034811 937 473 288 367 304 ptg000025l:354588-358701 Q3SYZ6 2.25e-34 Xylulose kinase (Xylulokinase) (EC 2.7.1.17) Bos taurus (Bovine) D-xylose metabolic process [GO:0042732]; phosphorylation [GO:0016310]; xylulose metabolic process [GO:0005997] GO:0004856; GO:0005524; GO:0005829; GO:0005997; GO:0016310; GO:0016773; GO:0042732 17138 FUN_034812 5914 6631 2977 3967 2996 NA NA NA NA NA NA NA 17139 FUN_034813 1794 2062 1068 1498 795 NA NA NA NA NA NA NA 17140 FUN_030313 5 0 6 0 22 ptg000023l:10588264-10589027 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17141 FUN_030317 4 0 5 1 21 ptg000023l:10596368-10597131 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17142 FUN_030315 5 0 7 0 28 ptg000023l:10592316-10593079 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17143 FUN_002143 0 0 0 0 34 NA NA NA NA NA NA NA 17144 FUN_042162 70 0 18 0 777 NA NA NA NA NA NA NA 17145 FUN_042165 25 0 59 97 83 NA NA NA NA NA NA NA 17146 FUN_042164 0 0 0 0 36 NA NA NA NA NA NA NA 17147 FUN_042167 0 5 5 0 10 NA NA NA NA NA NA NA 17148 FUN_042166 461 318 7 757 791 NA NA NA NA NA NA NA 17149 FUN_042169 0 0 6 0 0 NA NA NA NA NA NA NA 17150 FUN_042168 0 0 4 2 26 ptg000036l:1484613-1486182 Q7L622 2.58e-50 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Homo sapiens (Human) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005794; GO:0005829; GO:0006915; GO:0043231; GO:0046872 17151 FUN_039873 148 109 34 134 175 ptg000031l:1144815-1154129 A2AJ77 7.61e-39 PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12) Mus musculus (Mouse) detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; neuron projection development [GO:0031175]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; sensory perception of pain [GO:0019233] GO:0000122; GO:0003677; GO:0005634; GO:0005654; GO:0006479; GO:0008168; GO:0010468; GO:0019233; GO:0022008; GO:0031175; GO:0046872; GO:0050965; GO:0140713; GO:1900111; GO:1990226 17152 FUN_039873 148 109 34 134 175 ptg000031l:1144815-1154129 A2AJ77 1.39e-25 PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12) Mus musculus (Mouse) detection of temperature stimulus involved in sensory perception of pain [GO:0050965]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; neuron projection development [GO:0031175]; positive regulation of histone H3-K9 dimethylation [GO:1900111]; protein methylation [GO:0006479]; regulation of gene expression [GO:0010468]; sensory perception of pain [GO:0019233] GO:0000122; GO:0003677; GO:0005634; GO:0005654; GO:0006479; GO:0008168; GO:0010468; GO:0019233; GO:0022008; GO:0031175; GO:0046872; GO:0050965; GO:0140713; GO:1900111; GO:1990226 17153 FUN_003810 8 3 6 45 11 NA NA NA NA NA NA NA 17154 FUN_004848 489 554 329 515 883 NA NA NA NA NA NA NA 17155 FUN_004844 2772 5005 3135 3258 4119 NA NA NA NA NA NA NA 17156 FUN_004845 49 18 83 167 238 ntLink_8:27794836-27797109 Q9PTS8 2.29e-38 Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; regulation of nitric oxide metabolic process [GO:0080164]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0080164; GO:1904315 17157 FUN_004840 996 1030 1005 1052 1495 ntLink_8:27746967-27748175 P43144 1.82e-65 Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) Rattus norvegicus (Rat) cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; chemical synaptic transmission [GO:0007268]; chemical synaptic transmission, postsynaptic [GO:0099565]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; excitatory postsynaptic potential [GO:0060079]; inner ear morphogenesis [GO:0042472]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; nervous system process [GO:0050877]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; regulation of membrane potential [GO:0042391]; regulation of nitric oxide metabolic process [GO:0080164]; response to auditory stimulus [GO:0010996]; sensory perception of sound [GO:0007605]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0006812; GO:0007165; GO:0007204; GO:0007268; GO:0007605; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0042472; GO:0043005; GO:0045202; GO:0050877; GO:0050910; GO:0051899; GO:0060079; GO:0070373; GO:0080164; GO:0098655; GO:0098981; GO:0099565; GO:0099634; GO:1904315 17158 FUN_004841 1351 757 706 1577 1631 ntLink_8:27760827-27765016 P32297 2.76e-38 Neuronal acetylcholine receptor subunit alpha-3 Homo sapiens (Human) acetylcholine receptor signaling pathway [GO:0095500]; activation of transmembrane receptor protein tyrosine kinase activity [GO:0007171]; behavioral response to nicotine [GO:0035095]; chemical synaptic transmission [GO:0007268]; excitatory postsynaptic potential [GO:0060079]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; nervous system development [GO:0007399]; nervous system process [GO:0050877]; regulation of acetylcholine secretion, neurotransmission [GO:0014056]; regulation of dendrite morphogenesis [GO:0048814]; regulation of membrane potential [GO:0042391]; regulation of smooth muscle contraction [GO:0006940]; response to acetylcholine [GO:1905144]; signal transduction [GO:0007165]; synaptic transmission involved in micturition [GO:0060084]; synaptic transmission, cholinergic [GO:0007271] GO:0005231; GO:0005886; GO:0005892; GO:0006811; GO:0006940; GO:0007165; GO:0007171; GO:0007268; GO:0007271; GO:0007399; GO:0007626; GO:0014056; GO:0014069; GO:0015276; GO:0015464; GO:0016020; GO:0016607; GO:0022848; GO:0030425; GO:0030594; GO:0034220; GO:0035095; GO:0042166; GO:0042391; GO:0043005; GO:0043025; GO:0044853; GO:0045202; GO:0045211; GO:0048814; GO:0050877; GO:0051899; GO:0060079; GO:0060084; GO:0095500; GO:1904315; GO:1905144 17159 FUN_004842 28 0 14 8 27 ntLink_8:27769498-27773713 Q05941 3.53e-46 Neuronal acetylcholine receptor subunit alpha-7 Rattus norvegicus (Rat) acetylcholine receptor signaling pathway [GO:0095500]; associative learning [GO:0008306]; B cell activation [GO:0042113]; behavioral response to ethanol [GO:0048149]; behavioral response to nicotine [GO:0035095]; calcium ion transport [GO:0006816]; cation transmembrane transport [GO:0098655]; cellular calcium ion homeostasis [GO:0006874]; chemical synaptic transmission [GO:0007268]; cognition [GO:0050890]; dendrite arborization [GO:0140059]; dendritic spine organization [GO:0097061]; dopamine biosynthetic process [GO:0042416]; endocytosis [GO:0006897]; establishment of localization in cell [GO:0051649]; excitatory postsynaptic potential [GO:0060079]; flagellated sperm motility [GO:0030317]; generation of ovulation cycle rhythm [GO:0060112]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning or memory [GO:0007611]; membrane depolarization [GO:0051899]; memory [GO:0007613]; modulation of chemical synaptic transmission [GO:0050804]; modulation of excitatory postsynaptic potential [GO:0098815]; negative regulation of amyloid-beta formation [GO:1902430]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of tumor necrosis factor production [GO:0032720]; nervous system process [GO:0050877]; neuronal action potential [GO:0019228]; ovulation cycle [GO:0042698]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of CoA-transferase activity [GO:1905920]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure [GO:0001988]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein metabolic process [GO:0051247]; positive regulation of protein phosphorylation [GO:0001934]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of amyloid fibril formation [GO:1905906]; regulation of amyloid precursor protein catabolic process [GO:1902991]; regulation of inflammatory response [GO:0050727]; regulation of membrane potential [GO:0042391]; regulation of neuron death [GO:1901214]; regulation of nitric oxide metabolic process [GO:0080164]; regulation of norepinephrine secretion [GO:0014061]; regulation of response to drug [GO:2001023]; regulation of synaptic transmission, dopaminergic [GO:0032225]; response to acetylcholine [GO:1905144]; response to amyloid-beta [GO:1904645]; response to carbamate [GO:0046681]; response to cold [GO:0009409]; response to ethanol [GO:0045471]; response to food [GO:0032094]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; sensory processing [GO:0050893]; signal transduction [GO:0007165]; synapse organization [GO:0050808]; synaptic transmission, cholinergic [GO:0007271]; T cell activation [GO:0042110] GO:0001540; GO:0001666; GO:0001933; GO:0001934; GO:0001988; GO:0005216; GO:0005231; GO:0005737; GO:0005886; GO:0005892; GO:0006811; GO:0006816; GO:0006874; GO:0006897; GO:0007165; GO:0007268; GO:0007271; GO:0007611; GO:0007613; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0009897; GO:0010628; GO:0014061; GO:0014069; GO:0015464; GO:0015643; GO:0016020; GO:0016324; GO:0017081; GO:0019228; GO:0019901; GO:0022848; GO:0030317; GO:0030424; GO:0030425; GO:0030426; GO:0030594; GO:0030673; GO:0032094; GO:0032225; GO:0032279; GO:0032691; GO:0032715; GO:0032720; GO:0033138; GO:0034220; GO:0035094; GO:0035095; GO:0042110; GO:0042113; GO:0042166; GO:0042391; GO:0042416; GO:0042698; GO:0042734; GO:0042803; GO:0043005; GO:0043025; GO:0043197; GO:0043198; GO:0043410; GO:0044853; GO:0045121; GO:0045202; GO:0045211; GO:0045471; GO:0045766; GO:0046681; GO:0048149; GO:0050727; GO:0050728; GO:0050804; GO:0050808; GO:0050877; GO:0050890; GO:0050893; GO:0051117; GO:0051247; GO:0051649; GO:0051899; GO:0060079; GO:0060112; GO:0070373; GO:0070374; GO:0080164; GO:0095500; GO:0097061; GO:0097110; GO:0098655; GO:0098690; GO:0098815; GO:0098897; GO:0098981; GO:0099171; GO:0099634; GO:0140059; GO:1900273; GO:1901214; GO:1902004; GO:1902430; GO:1902991; GO:1904315; GO:1904645; GO:1905144; GO:1905906; GO:1905920; GO:2000463; GO:2001023 17160 FUN_004843 17 94 0 0 7 NA NA NA NA NA NA NA 17161 FUN_012811 23 5 9 2 6 NA NA NA NA NA NA NA 17162 FUN_012812 164 15 0 29 8 NA NA NA NA NA NA NA 17163 FUN_002855 0 0 0 0 9 NA NA NA NA NA NA NA 17164 FUN_002854 23 0 0 0 0 NA NA NA NA NA NA NA 17165 FUN_002857 0 15 14 0 34 NA NA NA NA NA NA NA 17166 FUN_002856 775 497 704 884 1405 NA NA NA NA NA NA NA 17167 FUN_002851 23 0 30 0 36 NA NA NA NA NA NA NA 17168 FUN_002853 20 0 21 3 48 NA NA NA NA NA NA NA 17169 FUN_031300 39 42 27 49 46 NA NA NA NA NA NA NA 17170 FUN_008286 335 712 125 258 132 NA NA NA NA NA NA NA 17171 FUN_008287 172 161 217 307 164 NA NA NA NA NA NA NA 17172 FUN_008284 498 261 231 299 279 ptg000002l:9946557-9948142 Q6P158 1.01e-30 Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57) Homo sapiens (Human) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0046872 17173 FUN_008285 134 116 89 180 638 ptg000002l:9949284-9957147 P97846 2.83e-29 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 17174 FUN_008282 969 1552 805 1174 1244 ptg000002l:9911971-9929166 Q9VCU9 6.28e-63 Endoribonuclease Dcr-1 (Protein dicer-1) (EC 3.1.26.-) Drosophila melanogaster (Fruit fly) apoptotic DNA fragmentation [GO:0006309]; dendrite morphogenesis [GO:0048813]; dsRNA transport [GO:0033227]; germ-line stem cell division [GO:0042078]; germarium-derived female germ-line cyst formation [GO:0030727]; germarium-derived oocyte fate determination [GO:0007294]; miRNA processing [GO:0035196]; mitotic cell cycle, embryonic [GO:0045448]; pole cell formation [GO:0007279]; pre-miRNA processing [GO:0031054]; response to starvation [GO:0042594]; RISC complex assembly [GO:0070922]; RNA phosphodiester bond hydrolysis [GO:0090501]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; segment polarity determination [GO:0007367]; siRNA processing [GO:0030422] GO:0003723; GO:0003727; GO:0004386; GO:0004525; GO:0004530; GO:0005524; GO:0005737; GO:0006309; GO:0007279; GO:0007294; GO:0007367; GO:0016442; GO:0016443; GO:0030422; GO:0030727; GO:0031054; GO:0033227; GO:0035194; GO:0035196; GO:0042078; GO:0042594; GO:0045448; GO:0046872; GO:0048813; GO:0070578; GO:0070883; GO:0070922; GO:0090501 17175 FUN_008283 2054 1299 1399 1774 1768 ptg000002l:9930264-9946152 Q6P5D3 3.19e-24 Putative ATP-dependent RNA helicase DHX57 (EC 3.6.4.13) (DEAH box protein 57) Mus musculus (Mouse) NA GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0046872 17176 FUN_008280 2391 2235 1057 1851 1815 ptg000002l:9901513-9905700 A7RP64 2.18e-23 RNA-binding protein pno1 Nematostella vectensis (Starlet sea anemone) NA GO:0003723; GO:0005730 17177 FUN_008281 3120 4641 1488 1801 1144 NA NA NA NA NA NA NA 17178 FUN_008288 1472 1886 1057 1070 1675 NA NA NA NA NA NA NA 17179 FUN_008289 706 664 349 768 562 NA NA NA NA NA NA NA 17180 FUN_009880 7 0 4 19 0 NA NA NA NA NA NA NA 17181 FUN_008758 7749 4080 3050 10186 6917 NA NA NA NA NA NA NA 17182 FUN_008759 305 106 79 305 0 NA NA NA NA NA NA NA 17183 FUN_008750 31 4 0 195 84 NA NA NA NA NA NA NA 17184 FUN_008751 8626 7809 3328 8266 4608 NA NA NA NA NA NA NA 17185 FUN_008752 1364 1001 480 1008 791 NA NA NA NA NA NA NA 17186 FUN_008754 337 178 271 218 261 NA NA NA NA NA NA NA 17187 FUN_008755 343 399 492 543 972 NA NA NA NA NA NA NA 17188 FUN_008756 789 600 317 293 506 NA NA NA NA NA NA NA 17189 FUN_008757 164 60 108 156 85 NA NA NA NA NA NA NA 17190 FUN_041539 395 421 423 356 336 NA NA NA NA NA NA NA 17191 FUN_041538 587 466 386 561 395 ptg000035l:4906394-4910464 B2VG45 1.81e-21 3'-5' ssDNA/RNA exonuclease TatD (EC 3.1.11.-) (EC 3.1.13.-) (DNase TatD) Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99) NA GO:0000175; GO:0000287; GO:0005737; GO:0008310 17192 FUN_000569 4780 3490 1659 2680 2665 NA NA NA NA NA NA NA 17193 FUN_000568 1807 1363 933 1262 1082 NA NA NA NA NA NA NA 17194 FUN_041533 1116 675 557 604 747 NA NA NA NA NA NA NA 17195 FUN_041532 1088 590 657 791 634 NA NA NA NA NA NA NA 17196 FUN_041531 621 730 391 822 831 NA NA NA NA NA NA NA 17197 FUN_041530 1079 1225 500 1051 777 NA NA NA NA NA NA NA 17198 FUN_000562 165 26 41 123 57 ntLink_6:4343586-4353598 Q149M9 4.52e-55 NACHT domain- and WD repeat-containing protein 1 Homo sapiens (Human) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of gene expression [GO:0010628] GO:0005524; GO:0005730; GO:0005829; GO:0010628; GO:0032088 17199 FUN_041535 265 159 0 261 199 NA NA NA NA NA NA NA 17200 FUN_033137 73 65 33 43 35 ptg000023l:40359825-40360752 Q8BR76 5.41e-39 Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67) Mus musculus (Mouse) branching morphogenesis of an epithelial tube [GO:0048754]; cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; head development [GO:0060322]; heart development [GO:0007507]; kidney development [GO:0001822]; negative regulation of centrosome duplication [GO:0010826]; non-canonical Wnt signaling pathway [GO:0035567]; photoreceptor cell outer segment organization [GO:0035845]; positive regulation of ERAD pathway [GO:1904294]; positive regulation of non-motile cilium assembly [GO:1902857]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0001822; GO:0005789; GO:0005813; GO:0005886; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0010826; GO:0030433; GO:0030659; GO:0031005; GO:0035567; GO:0035845; GO:0035869; GO:0036038; GO:0048754; GO:0051082; GO:0051787; GO:0060170; GO:0060271; GO:0060322; GO:0060441; GO:1902857; GO:1904294 17201 FUN_033135 5 0 2 0 11 NA NA NA NA NA NA NA 17202 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.04e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17203 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.04e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17204 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 5.44e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17205 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 5.44e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17206 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.3e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17207 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.3e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17208 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 3.42e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17209 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 3.42e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17210 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 4.85e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17211 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 4.85e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17212 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.95e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17213 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 4.38e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17214 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 3.17e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17215 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 2.08e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17216 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 4.22e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17217 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 6.72e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17218 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 2.87e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17219 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.87e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17220 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 8.02e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17221 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 1.56e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17222 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 3.68e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17223 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 3.25e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17224 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 2.42e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17225 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 6.06e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17226 FUN_033133 31 7 6 0 0 ptg000023l:40319494-40321943 Q96AY4 2.97e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17227 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 3.15e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17228 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 3.29e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17229 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 1.97e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17230 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 6.55e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17231 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 8.4e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17232 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 8.5e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17233 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 7.1e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17234 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 4.8e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17235 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 8.01e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17236 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 2.62e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17237 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 1.29e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17238 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 6.74e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17239 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 8.7e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17240 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 1.8e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17241 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 1.6e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17242 FUN_033131 0 0 21 0 0 ptg000023l:40297454-40298521 Q96AY4 1.53e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17243 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17244 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17245 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17246 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17247 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17248 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 1.45e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17249 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 2.17e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17250 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 3.42e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17251 FUN_033139 5 19 10 35 7 ptg000023l:40365462-40369359 Q96AY4 4.36e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17252 FUN_016662 158 29 111 0 247 NA NA NA NA NA NA NA 17253 FUN_016661 578 610 149 277 475 ptg000011l:6048744-6050804 Q5RCI5 3.15e-24 Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT) (EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) peptidyl-lysine dimethylation [GO:0018027]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; protein methylation [GO:0006479] GO:0005739; GO:0006479; GO:0016278; GO:0016279; GO:0018023; GO:0018026; GO:0018027 17254 FUN_016660 6147 6149 2046 8940 7913 NA NA NA NA NA NA NA 17255 FUN_016667 1155 381 692 1372 988 NA NA NA NA NA NA NA 17256 FUN_016666 811 76 47 101 494 NA NA NA NA NA NA NA 17257 FUN_042945 4 77 63 28 22 NA NA NA NA NA NA NA 17258 FUN_042944 0 3 64 0 43 NA NA NA NA NA NA NA 17259 FUN_016669 183 108 76 68 113 NA NA NA NA NA NA NA 17260 FUN_016668 1000 449 506 617 879 NA NA NA NA NA NA NA 17261 FUN_012494 956 876 385 1133 1880 NA NA NA NA NA NA NA 17262 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 2.37e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17263 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 4.64e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17264 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 8.63e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17265 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 1.73e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17266 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 9.53e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17267 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 1.25e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17268 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 6.95e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17269 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 1.69e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17270 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 3.76e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17271 FUN_029516 1175 852 523 631 489 ptg000023l:2702329-2711287 Q96AY4 5.47e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17272 FUN_012497 597 418 284 310 155 NA NA NA NA NA NA NA 17273 FUN_029512 2 0 19 6 0 NA NA NA NA NA NA NA 17274 FUN_029511 1480 285 1033 913 800 ptg000023l:2624886-2633620 Q96AY4 1.05e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17275 FUN_029511 1480 285 1033 913 800 ptg000023l:2624886-2633620 Q96AY4 7.69e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17276 FUN_029511 1480 285 1033 913 800 ptg000023l:2624886-2633620 Q96AY4 2.34e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17277 FUN_029511 1480 285 1033 913 800 ptg000023l:2624886-2633620 Q96AY4 1.23e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17278 FUN_029511 1480 285 1033 913 800 ptg000023l:2624886-2633620 Q96AY4 3.81e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17279 FUN_029511 1480 285 1033 913 800 ptg000023l:2624886-2633620 Q96AY4 4.29e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17280 FUN_012493 24 0 0 25 0 NA NA NA NA NA NA NA 17281 FUN_010500 1 13 3 13 5 NA NA NA NA NA NA NA 17282 FUN_010502 111 54 52 47 52 NA NA NA NA NA NA NA 17283 FUN_010504 0 367 0 0 0 NA NA NA NA NA NA NA 17284 FUN_010505 0 482 0 0 7 NA NA NA NA NA NA NA 17285 FUN_010506 15 4 6 13 4 NA NA NA NA NA NA NA 17286 FUN_010507 8 5 18 7 22 NA NA NA NA NA NA NA 17287 FUN_016708 1331 1257 759 1322 1694 NA NA NA NA NA NA NA 17288 FUN_016709 856 2458 682 2436 2111 ptg000011l:6490245-6502076 Q7ZTV5 7.28e-81 Follicle-stimulating hormone receptor (FSH-R) (Follitropin receptor) Cairina moschata (Muscovy duck) cellular response to follicle-stimulating hormone stimulus [GO:0071372]; follicle-stimulating hormone signaling pathway [GO:0042699]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; regulation of protein kinase A signaling [GO:0010738] GO:0004930; GO:0004963; GO:0005886; GO:0007186; GO:0010738; GO:0014068; GO:0016020; GO:0042699; GO:0043235; GO:0070374; GO:0071372 17289 FUN_016704 337 181 238 283 182 NA NA NA NA NA NA NA 17290 FUN_042865 0 8 0 0 0 NA NA NA NA NA NA NA 17291 FUN_042866 1268 1482 917 822 829 NA NA NA NA NA NA NA 17292 FUN_016700 1051 2023 1020 1208 826 NA NA NA NA NA NA NA 17293 FUN_042861 4 26 0 0 5 NA NA NA NA NA NA NA 17294 FUN_016702 48 30 49 82 15 NA NA NA NA NA NA NA 17295 FUN_042863 0 4382 13 16 2701 NA NA NA NA NA NA NA 17296 FUN_011671 6 0 0 5 4 NA NA NA NA NA NA NA 17297 FUN_011673 6 0 0 0 0 NA NA NA NA NA NA NA 17298 FUN_013743 36 21 0 70 19 NA NA NA NA NA NA NA 17299 FUN_013742 577 707 4 485 412 NA NA NA NA NA NA NA 17300 FUN_014533 1131 702 390 869 787 NA NA NA NA NA NA NA 17301 FUN_014534 129 90 201 94 118 ptg000009l:1008054-1009728 Q9N0E1 3.28e-22 Acetoacetyl-CoA synthetase (EC 6.2.1.16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005829; GO:0006631; GO:0030729 17302 FUN_014534 129 90 201 94 118 ptg000009l:1008054-1009728 Q9N0E1 3.28e-22 Acetoacetyl-CoA synthetase (EC 6.2.1.16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005829; GO:0006631; GO:0030729 17303 FUN_014534 129 90 201 94 118 ptg000009l:1008054-1009728 Q9N0E1 3.28e-22 Acetoacetyl-CoA synthetase (EC 6.2.1.16) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) fatty acid metabolic process [GO:0006631] GO:0005524; GO:0005829; GO:0006631; GO:0030729 17304 FUN_014539 3494 2956 1715 3194 4771 NA NA NA NA NA NA NA 17305 FUN_014538 224 71 890 222 157 ptg000009l:1045494-1051870 G5EF51 2.46e-32 Lim and transglutaminase domain protein ltd-1 (Kyphoscoliosis inactive peptidase homolog ltd-1) Caenorhabditis elegans muscle structure development [GO:0061061] GO:0005737; GO:0005856; GO:0005911; GO:0046872; GO:0055120; GO:0061061 17306 FUN_040674 21 0 18 0 5 NA NA NA NA NA NA NA 17307 FUN_010895 3438 3279 2278 4224 3635 ptg000007l:4041301-4044225 P06603 2.35e-104 Tubulin alpha-1 chain (EC 3.6.5.-) Drosophila melanogaster (Fruit fly) lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000235; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0016787; GO:0032418; GO:0046872; GO:0048471 17308 FUN_010895 3438 3279 2278 4224 3635 ptg000007l:4041301-4044225 P06603 2.88e-70 Tubulin alpha-1 chain (EC 3.6.5.-) Drosophila melanogaster (Fruit fly) lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000235; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0016787; GO:0032418; GO:0046872; GO:0048471 17309 FUN_010895 3438 3279 2278 4224 3635 ptg000007l:4041301-4044225 P06603 6.77e-43 Tubulin alpha-1 chain (EC 3.6.5.-) Drosophila melanogaster (Fruit fly) lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000235; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0016787; GO:0032418; GO:0046872; GO:0048471 17310 FUN_010895 3438 3279 2278 4224 3635 ptg000007l:4041301-4044225 P06603 1.65e-22 Tubulin alpha-1 chain (EC 3.6.5.-) Drosophila melanogaster (Fruit fly) lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000235; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0016787; GO:0032418; GO:0046872; GO:0048471 17311 FUN_040679 36 0 24 0 6 NA NA NA NA NA NA NA 17312 FUN_026398 435 159 36 72 232 ptg000020l:8369741-8376299 O22943 4.51e-67 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 17313 FUN_026399 1953 743 449 707 264 NA NA NA NA NA NA NA 17314 FUN_010118 36 0 0 0 330 NA NA NA NA NA NA NA 17315 FUN_026391 599 180 194 477 495 NA NA NA NA NA NA NA 17316 FUN_026392 553 209 159 448 385 NA NA NA NA NA NA NA 17317 FUN_026393 810 387 291 617 348 NA NA NA NA NA NA NA 17318 FUN_026394 608 402 337 590 377 NA NA NA NA NA NA NA 17319 FUN_026395 1076 1094 947 810 522 NA NA NA NA NA NA NA 17320 FUN_026396 619 439 83 525 545 ptg000020l:8351354-8364084 O22943 2.44e-65 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 17321 FUN_026396 619 439 83 525 545 ptg000020l:8351354-8364084 O22943 2.75e-65 Probable glycosyltransferase STELLO1 (EC 2.4.-.-) Arabidopsis thaliana (Mouse-ear cress) plant-type cell wall cellulose biosynthetic process [GO:0052324]; regulation of plant-type cell wall cellulose biosynthetic process [GO:2001009] GO:0000139; GO:0005768; GO:0005794; GO:0005802; GO:0016757; GO:0042802; GO:0052324; GO:2001009 17322 FUN_026397 5 3 6 1 3 NA NA NA NA NA NA NA 17323 FUN_022899 1992 2178 1380 1816 1419 NA NA NA NA NA NA NA 17324 FUN_022898 296 88 129 190 138 NA NA NA NA NA NA NA 17325 FUN_022897 4175 2102 1764 3924 2147 ptg000017l:1255233-1255890 A6QNP3 2.92e-31 Protein phosphatase 1 regulatory subunit 3B Bos taurus (Bovine) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0019888; GO:2001069 17326 FUN_022896 511 448 347 406 468 NA NA NA NA NA NA NA 17327 FUN_022895 331 285 148 344 947 ptg000017l:1234653-1245637 P45845 3.96e-25 Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase) [Cleaved into: Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form] Sus scrofa (Pig) blood vessel morphogenesis [GO:0048514]; collagen fibril organization [GO:0030199]; peptidyl-lysine oxidation [GO:0018057] GO:0004720; GO:0005507; GO:0005518; GO:0005576; GO:0005615; GO:0018057; GO:0030199; GO:0048514; GO:0062023 17328 FUN_022894 2622 2670 2180 4113 4379 ptg000017l:1225217-1232810 P97873 7.89e-28 Lysyl oxidase homolog 1 (EC 1.4.3.-) (Lysyl oxidase 2) (Lysyl oxidase-like protein 1) Mus musculus (Mouse) collagen fibril organization [GO:0030199]; peptidyl-lysine oxidation [GO:0018057] GO:0001669; GO:0004720; GO:0005507; GO:0005604; GO:0005615; GO:0005737; GO:0016641; GO:0018057; GO:0030199; GO:0031012; GO:0062023 17329 FUN_022893 1251 767 661 1338 1236 ptg000017l:1214556-1223669 P45845 4.8e-27 Protein-lysine 6-oxidase (EC 1.4.3.13) (Lysyl oxidase) [Cleaved into: Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form] Sus scrofa (Pig) blood vessel morphogenesis [GO:0048514]; collagen fibril organization [GO:0030199]; peptidyl-lysine oxidation [GO:0018057] GO:0004720; GO:0005507; GO:0005518; GO:0005576; GO:0005615; GO:0018057; GO:0030199; GO:0048514; GO:0062023 17330 FUN_022892 133 128 60 184 114 ptg000017l:1212978-1213998 Q9R1C8 2.45e-24 5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6) Mus musculus (Mouse) cerebral cortex cell migration [GO:0021795]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; learning [GO:0007612]; long-term synaptic potentiation [GO:0060291]; negative regulation of acetylcholine secretion, neurotransmission [GO:0014058]; negative regulation of gamma-aminobutyric acid secretion [GO:0014053]; negative regulation of glutamate secretion [GO:0014050]; positive regulation of dopamine secretion [GO:0033603]; positive regulation of gamma-aminobutyric acid secretion [GO:0014054]; positive regulation of TOR signaling [GO:0032008] GO:0004993; GO:0005886; GO:0005929; GO:0007187; GO:0007268; GO:0007612; GO:0014050; GO:0014053; GO:0014054; GO:0014058; GO:0021795; GO:0030425; GO:0030594; GO:0032008; GO:0033603; GO:0045202; GO:0060291 17331 FUN_022891 17 67 22 19 92 ptg000017l:1178067-1179183 P25931 1.75e-26 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 17332 FUN_022890 765 211 408 353 694 ptg000017l:1168493-1176922 Q9DBV3 1.84e-80 Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34) (DExH-box helicase 34) Mus musculus (Mouse) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of phosphorylation [GO:0042327] GO:0000184; GO:0000956; GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0042327; GO:0044877; GO:2000623 17333 FUN_022890 765 211 408 353 694 ptg000017l:1168493-1176922 Q9DBV3 1.5e-54 Probable ATP-dependent RNA helicase DHX34 (EC 3.6.4.13) (DEAH box protein 34) (DExH-box helicase 34) Mus musculus (Mouse) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:2000623]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of phosphorylation [GO:0042327] GO:0000184; GO:0000956; GO:0003723; GO:0003724; GO:0005524; GO:0016887; GO:0042327; GO:0044877; GO:2000623 17334 FUN_029719 4263 1258 1086 3263 940 ptg000023l:4928532-4941494 Q9NUV9 1.35e-23 GTPase IMAP family member 4 (Immunity-associated nucleotide 1 protein) (IAN-1) (hIAN1) (Immunity-associated protein 4) Homo sapiens (Human) NA GO:0005525; GO:0005829; GO:0043231 17335 FUN_029718 160 32 73 310 55 NA NA NA NA NA NA NA 17336 FUN_029711 693 547 334 870 726 NA NA NA NA NA NA NA 17337 FUN_029710 345 247 149 306 160 NA NA NA NA NA NA NA 17338 FUN_029713 12 0 15 0 0 NA NA NA NA NA NA NA 17339 FUN_029712 19 0 11 0 0 NA NA NA NA NA NA NA 17340 FUN_029715 206 131 341 856 205 NA NA NA NA NA NA NA 17341 FUN_029717 0 32 0 0 0 NA NA NA NA NA NA NA 17342 FUN_029716 242 181 270 175 279 NA NA NA NA NA NA NA 17343 FUN_023418 1638 1103 611 1118 3712 NA NA NA NA NA NA NA 17344 FUN_023419 330 232 164 124 123 ptg000017l:7319616-7322403 Q8N9I5 2.1e-77 Fatty acid desaturase 6 (EC 1.14.19.-) Homo sapiens (Human) fatty acid biosynthetic process [GO:0006633]; lipid metabolic process [GO:0006629] GO:0006629; GO:0006633; GO:0016020; GO:0016717 17345 FUN_023414 80 20 22 31 33 NA NA NA NA NA NA NA 17346 FUN_023415 211 277 107 276 405 ptg000017l:7284502-7288450 Q5SWK7 6.77e-42 RING finger protein 145 (EC 2.3.2.27) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0008270; GO:0012505; GO:0061630 17347 FUN_023416 19297 14256 10651 12478 9164 ptg000017l:7288683-7300240 Q2HJG2 1.94e-23 Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) Bos taurus (Bovine) alternative mRNA splicing, via spliceosome [GO:0000380]; apoptotic process [GO:0006915]; mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000380; GO:0000381; GO:0003677; GO:0003723; GO:0005634; GO:0006376; GO:0006915; GO:1990904 17348 FUN_023417 7302 8838 4613 4267 3581 NA NA NA NA NA NA NA 17349 FUN_023410 11338 6945 6525 9551 5047 NA NA NA NA NA NA NA 17350 FUN_023411 7193 6468 4418 11168 8789 NA NA NA NA NA NA NA 17351 FUN_023412 1371 1331 853 1894 1118 NA NA NA NA NA NA NA 17352 FUN_023413 460 368 189 483 337 NA NA NA NA NA NA NA 17353 FUN_039949 10 51 0 18 105 NA NA NA NA NA NA NA 17354 FUN_039948 1542 1242 1074 1724 1281 NA NA NA NA NA NA NA 17355 FUN_039945 204 261 167 257 270 NA NA NA NA NA NA NA 17356 FUN_039944 154 140 4 79 68 NA NA NA NA NA NA NA 17357 FUN_039947 1627 1530 1139 1050 903 NA NA NA NA NA NA NA 17358 FUN_039946 1368 1047 628 519 471 ptg000031l:1990301-1993906 Q5XGI5 1.38e-41 WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 17359 FUN_039941 0 57 82 55 91 NA NA NA NA NA NA NA 17360 FUN_039943 1019 787 193 373 109 NA NA NA NA NA NA NA 17361 FUN_039942 33 12 26 68 70 NA NA NA NA NA NA NA 17362 FUN_015378 60 92 41 38 94 NA NA NA NA NA NA NA 17363 FUN_015379 9 17 43 36 106 NA NA NA NA NA NA NA 17364 FUN_015370 138 49 67 147 141 NA NA NA NA NA NA NA 17365 FUN_015371 45 2 23 0 129 NA NA NA NA NA NA NA 17366 FUN_015372 314 217 184 699 390 ptg000009l:9371977-9373090 A5D8R3 1.34e-25 Transcription factor Sox-17-beta.3 (SRY (sex determining region Y)-box 17-beta.3) Xenopus laevis (African clawed frog) gastrulation [GO:0007369]; Wnt signaling pathway [GO:0016055] GO:0003677; GO:0005634; GO:0007369; GO:0016055 17367 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 5.41e-54 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17368 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 4.08e-31 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17369 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 4.99e-31 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17370 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 1.91e-27 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17371 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 4.98e-27 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17372 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 1.41e-21 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17373 FUN_015373 4811 3814 1507 3870 3067 ptg000009l:9412551-9438451 O42131 3.45e-21 DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme) Gallus gallus (Chicken) B cell differentiation [GO:0030183]; DNA topological change [GO:0006265]; resolution of meiotic recombination intermediates [GO:0000712]; sister chromatid segregation [GO:0000819] GO:0000712; GO:0000819; GO:0003677; GO:0003916; GO:0003918; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0006265; GO:0030183; GO:0046872; GO:1990904 17374 FUN_015375 33 16 8 6 17 NA NA NA NA NA NA NA 17375 FUN_015376 15 53 0 29 21 NA NA NA NA NA NA NA 17376 FUN_015377 306 173 180 300 459 NA NA NA NA NA NA NA 17377 FUN_018539 0 0 16 0 6 NA NA NA NA NA NA NA 17378 FUN_018538 3 0 5 16 0 NA NA NA NA NA NA NA 17379 FUN_016077 1213 730 513 1041 924 ptg000010l:1335627-1339513 Q9V3D2 1.6e-33 Oxygen-dependent coproporphyrinogen-III oxidase (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3) Drosophila melanogaster (Fruit fly) heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004109; GO:0005737; GO:0005739; GO:0005758; GO:0006782; GO:0006783; GO:0042803 17380 FUN_016077 1213 730 513 1041 924 ptg000010l:1335627-1339513 Q9V3D2 8.37e-24 Oxygen-dependent coproporphyrinogen-III oxidase (COX) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3) Drosophila melanogaster (Fruit fly) heme biosynthetic process [GO:0006783]; protoporphyrinogen IX biosynthetic process [GO:0006782] GO:0004109; GO:0005737; GO:0005739; GO:0005758; GO:0006782; GO:0006783; GO:0042803 17381 FUN_018535 251 644 320 1736 149 ptg000012l:10566664-10567888 Q2M3R5 1.58e-47 Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005789; GO:0005886; GO:0016020; GO:0051480; GO:1990034 17382 FUN_018534 257 838 124 2157 298 ptg000012l:10548167-10549403 Q2M3R5 2.7e-47 Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005789; GO:0005886; GO:0016020; GO:0051480; GO:1990034 17383 FUN_018537 164 219 29 146 112 ptg000012l:10601213-10614709 P21328 2.08e-22 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 17384 FUN_018536 2254 901 803 1586 1715 NA NA NA NA NA NA NA 17385 FUN_018531 576 329 197 164 377 ptg000012l:10533557-10535189 Q9H9S5 1.2e-142 Ribitol 5-phosphate transferase FKRP (EC 2.7.8.-) (Fukutin-related protein) (Ribitol-5-phosphate transferase) Homo sapiens (Human) protein O-linked mannosylation [GO:0035269]; protein processing [GO:0016485]; protein tetramerization [GO:0051262] GO:0000139; GO:0002162; GO:0005615; GO:0005654; GO:0005791; GO:0005794; GO:0005829; GO:0016485; GO:0016780; GO:0035269; GO:0042383; GO:0042802; GO:0046872; GO:0051262 17386 FUN_016074 998 754 504 629 337 NA NA NA NA NA NA NA 17387 FUN_018533 329 504 166 259 297 ptg000012l:10544507-10546127 Q8BVT6 7.18e-35 Protein phosphatase 2C-like domain-containing protein 1 Mus musculus (Mouse) protein dephosphorylation [GO:0006470] GO:0004722; GO:0006470 17388 FUN_018532 2342 1702 583 1068 1210 NA NA NA NA NA NA NA 17389 FUN_016072 10 12 5 19 18 NA NA NA NA NA NA NA 17390 FUN_016073 11582 11993 8445 11192 8417 ptg000010l:1302102-1305452 Q26540 5.54e-37 14-3-3 protein homolog 1 Schistosoma mansoni (Blood fluke) NA NA 17391 FUN_016070 10345 9517 4847 8744 5800 ptg000010l:1275334-1283624 P62262 3.4e-47 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 17392 FUN_016070 10345 9517 4847 8744 5800 ptg000010l:1275334-1283624 P62262 8.61e-34 14-3-3 protein epsilon (14-3-3E) (Protein kinase C inhibitor protein 1) (KCIP-1) Ovis aries (Sheep) cellular response to heat [GO:0034605]; MAPK cascade [GO:0000165]; positive regulation of protein export from nucleus [GO:0046827]; protein localization to nucleus [GO:0034504] GO:0000165; GO:0005634; GO:0005737; GO:0034504; GO:0034605; GO:0042470; GO:0046827 17393 FUN_016071 1393 915 866 1039 775 NA NA NA NA NA NA NA 17394 FUN_025153 26 0 21 0 60 NA NA NA NA NA NA NA 17395 FUN_025152 3 0 6 0 47 NA NA NA NA NA NA NA 17396 FUN_025151 36 0 11 0 61 ptg000018l:14562642-14571086 P14381 2.97e-107 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 17397 FUN_025150 4 0 0 0 21 NA NA NA NA NA NA NA 17398 FUN_024824 0 0 0 0 56 NA NA NA NA NA NA NA 17399 FUN_024826 0 0 2 0 33 NA NA NA NA NA NA NA 17400 FUN_024827 8 2 4 0 35 NA NA NA NA NA NA NA 17401 FUN_024821 28 15 48 0 53 NA NA NA NA NA NA NA 17402 FUN_024822 0 15 0 0 14 NA NA NA NA NA NA NA 17403 FUN_016079 115 169 126 113 188 NA NA NA NA NA NA NA 17404 FUN_024828 54 0 0 0 0 NA NA NA NA NA NA NA 17405 FUN_038304 139 83 116 182 71 NA NA NA NA NA NA NA 17406 FUN_038305 16 2 14 15 11 NA NA NA NA NA NA NA 17407 FUN_038306 449 117 150 351 196 NA NA NA NA NA NA NA 17408 FUN_038307 1066 45 60 408 310 NA NA NA NA NA NA NA 17409 FUN_038300 2514 1713 1044 1989 2115 ptg000027l:5421225-5450703 E9PY46 6.06e-30 Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; embryonic brain development [GO:1990403]; embryonic camera-type eye development [GO:0031076]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digit morphogenesis [GO:0042733]; heart development [GO:0007507]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; limb morphogenesis [GO:0035108]; neural tube patterning [GO:0021532]; non-motile cilium assembly [GO:1905515]; photoreceptor cell outer segment organization [GO:0035845]; protein localization to cilium [GO:0061512]; regulation of cilium assembly [GO:1902017]; regulation of smoothened signaling pathway [GO:0008589] GO:0005813; GO:0005814; GO:0005929; GO:0005930; GO:0007368; GO:0007507; GO:0008589; GO:0021532; GO:0030991; GO:0031076; GO:0032391; GO:0035108; GO:0035721; GO:0035845; GO:0036064; GO:0042073; GO:0042733; GO:0048701; GO:0060271; GO:0061512; GO:0097730; GO:0120199; GO:1902017; GO:1905515; GO:1990403 17410 FUN_038301 350 149 42 160 224 NA NA NA NA NA NA NA 17411 FUN_038302 3245 2444 2547 3105 2780 NA NA NA NA NA NA NA 17412 FUN_038303 7706 8221 4820 6763 3432 NA NA NA NA NA NA NA 17413 FUN_038308 2352 83 178 1615 1452 NA NA NA NA NA NA NA 17414 FUN_038309 185 122 175 107 112 NA NA NA NA NA NA NA 17415 FUN_016156 405 165 137 229 272 NA NA NA NA NA NA NA 17416 FUN_014298 444 204 107 103 119 NA NA NA NA NA NA NA 17417 FUN_019669 0 0 0 4 14 NA NA NA NA NA NA NA 17418 FUN_014290 23 0 13 0 51 NA NA NA NA NA NA NA 17419 FUN_014291 47 0 13 5 81 NA NA NA NA NA NA NA 17420 FUN_014293 4 17 32 0 14 NA NA NA NA NA NA NA 17421 FUN_034058 1154 386 563 727 441 ptg000024l:4263289-4280652 Q3ZCC3 1.3e-39 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 17422 FUN_035307 0 0 0 12 0 NA NA NA NA NA NA NA 17423 FUN_035306 45 18 0 0 0 NA NA NA NA NA NA NA 17424 FUN_030153 8 1 0 0 11 NA NA NA NA NA NA NA 17425 FUN_044205 0 0 4 1 6 NA NA NA NA NA NA NA 17426 FUN_035303 353 230 44 220 98 NA NA NA NA NA NA NA 17427 FUN_035302 1318 931 610 711 516 NA NA NA NA NA NA NA 17428 FUN_035301 53 157 20 9 71 NA NA NA NA NA NA NA 17429 FUN_035300 210 210 59 118 67 NA NA NA NA NA NA NA 17430 FUN_030159 38 56 45 12 257 NA NA NA NA NA NA NA 17431 FUN_035309 210 145 217 92 137 ptg000025l:6265124-6265978 A0A3M6TIF0 1.08e-125 NA NA NA NA 17432 FUN_035308 12 0 0 10 0 NA NA NA NA NA NA NA 17433 FUN_031686 2396 1702 998 2228 1576 ptg000023l:24393727-24406152 Q9N0F1 3.68e-24 Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) (E2o) (PE2o) Sus scrofa (Pig) 2-oxoglutarate metabolic process [GO:0006103]; histone succinylation [GO:0106077]; L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; succinyl-CoA metabolic process [GO:0006104]; tricarboxylic acid cycle [GO:0006099] GO:0004149; GO:0005634; GO:0005739; GO:0005759; GO:0006099; GO:0006103; GO:0006104; GO:0033512; GO:0045252; GO:0106077 17434 FUN_031684 148 96 0 0 0 NA NA NA NA NA NA NA 17435 FUN_031685 241 173 147 206 106 NA NA NA NA NA NA NA 17436 FUN_031680 322 206 121 127 170 NA NA NA NA NA NA NA 17437 FUN_001968 1 54 35 11 19 NA NA NA NA NA NA NA 17438 FUN_001969 60 0 13 369 14 NA NA NA NA NA NA NA 17439 FUN_036658 14 9 40 13 69 NA NA NA NA NA NA NA 17440 FUN_031688 1133 898 1224 1979 1334 NA NA NA NA NA NA NA 17441 FUN_031689 34 80 12 87 17 NA NA NA NA NA NA NA 17442 FUN_013105 19 0 0 32 0 NA NA NA NA NA NA NA 17443 FUN_030488 8 1 12 0 40 ptg000023l:10982866-10983629 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17444 FUN_030482 8 0 11 0 30 ptg000023l:10970710-10971473 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17445 FUN_030480 7 0 10 0 47 ptg000023l:10966658-10967421 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17446 FUN_030486 10 0 8 0 37 ptg000023l:10978814-10979577 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17447 FUN_030484 8 0 10 0 40 ptg000023l:10974762-10975525 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 17448 FUN_037229 3381 3186 1659 3631 3941 NA NA NA NA NA NA NA 17449 FUN_039168 25 8 11 2 9 NA NA NA NA NA NA NA 17450 FUN_039167 0 0 0 0 8 NA NA NA NA NA NA NA 17451 FUN_039166 21 4 7 64 19 NA NA NA NA NA NA NA 17452 FUN_039164 6 2 1 2 3 NA NA NA NA NA NA NA 17453 FUN_039162 0 0 0 6 0 NA NA NA NA NA NA NA 17454 FUN_027705 0 0 0 6 0 NA NA NA NA NA NA NA 17455 FUN_027706 11 6 18 0 23 NA NA NA NA NA NA NA 17456 FUN_027707 1 4 3 1 6 NA NA NA NA NA NA NA 17457 FUN_027701 356 484 501 360 505 NA NA NA NA NA NA NA 17458 FUN_027702 0 0 0 6 0 NA NA NA NA NA NA NA 17459 FUN_027708 0 3 22 0 16 NA NA NA NA NA NA NA 17460 FUN_027709 5 0 3 2 18 NA NA NA NA NA NA NA 17461 FUN_024410 930 662 408 902 709 NA NA NA NA NA NA NA 17462 FUN_023612 3 14 4 0 3 NA NA NA NA NA NA NA 17463 FUN_023613 21 0 1 0 4 NA NA NA NA NA NA NA 17464 FUN_038616 170 80 114 80 60 NA NA NA NA NA NA NA 17465 FUN_038617 1244 564 798 1155 817 ptg000027l:9367865-9382259 Q99LD4 1.21e-27 COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) Mus musculus (Mouse) protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0008180 17466 FUN_038617 1244 564 798 1155 817 ptg000027l:9367865-9382259 Q99LD4 1.21e-27 COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) Mus musculus (Mouse) protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0008180 17467 FUN_038617 1244 564 798 1155 817 ptg000027l:9367865-9382259 Q99LD4 1.21e-27 COP9 signalosome complex subunit 1 (SGN1) (Signalosome subunit 1) (G protein pathway suppressor 1) (GPS-1) (JAB1-containing signalosome subunit 1) Mus musculus (Mouse) protein deneddylation [GO:0000338] GO:0000338; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0008180 17468 FUN_031358 257 62 124 0 167 NA NA NA NA NA NA NA 17469 FUN_026223 5 0 0 12 9 NA NA NA NA NA NA NA 17470 FUN_026224 102 43 29 73 19 NA NA NA NA NA NA NA 17471 FUN_031352 292 205 124 0 256 NA NA NA NA NA NA NA 17472 FUN_031353 70 77 47 0 189 NA NA NA NA NA NA NA 17473 FUN_031354 37 222 49 0 77 NA NA NA NA NA NA NA 17474 FUN_031355 21 28 0 0 0 NA NA NA NA NA NA NA 17475 FUN_023617 37 98 89 97 169 NA NA NA NA NA NA NA 17476 FUN_031538 16 91 165 6703 187 NA NA NA NA NA NA NA 17477 FUN_037219 1423 1425 1055 1146 1409 NA NA NA NA NA NA NA 17478 FUN_037218 850 565 382 1762 339 NA NA NA NA NA NA NA 17479 FUN_037217 510 114 118 262 83 ptg000026l:7187397-7201582 Q8BFR2 6.01e-23 Follistatin-related protein 5 (Follistatin-like protein 5) (m-D/Bsp120I 1-2) Mus musculus (Mouse) cell differentiation [GO:0030154] GO:0005509; GO:0005576; GO:0030154 17480 FUN_037216 3401 4862 3190 2425 2151 NA NA NA NA NA NA NA 17481 FUN_037215 98 73 0 0 0 NA NA NA NA NA NA NA 17482 FUN_037214 1658 1147 852 1193 656 NA NA NA NA NA NA NA 17483 FUN_037213 9500 5855 3133 7934 6274 NA NA NA NA NA NA NA 17484 FUN_037212 355 200 197 181 182 NA NA NA NA NA NA NA 17485 FUN_037211 505 675 384 670 896 NA NA NA NA NA NA NA 17486 FUN_037210 2160 4612 6167 1388 1444 NA NA NA NA NA NA NA 17487 FUN_028644 0 0 13 0 22 NA NA NA NA NA NA NA 17488 FUN_006758 0 0 11 72 89 NA NA NA NA NA NA NA 17489 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 9.73e-59 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17490 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 1.9e-55 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17491 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 4.22e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17492 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 1.9e-53 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17493 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 2.1e-48 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17494 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 3.47e-42 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17495 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 4.03e-36 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17496 FUN_026229 1308 191 230 212 294 ptg000020l:6422597-6441594 P16157 8.69e-26 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 17497 FUN_006756 4792 7897 2486 868 1556 NA NA NA NA NA NA NA 17498 FUN_006757 23 0 17 28 28 NA NA NA NA NA NA NA 17499 FUN_006754 42 428 41 260 122 NA NA NA NA NA NA NA 17500 FUN_006755 12 183 76 217 27 NA NA NA NA NA NA NA 17501 FUN_006752 307 709 135 146 156 NA NA NA NA NA NA NA 17502 FUN_023618 74 72 28 72 27 NA NA NA NA NA NA NA 17503 FUN_006750 2190 1725 1094 2155 1902 ptg000001l:16187274-16204654 Q3ZT31 3.55e-43 Sorting nexin-25 Mus musculus (Mouse) negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; protein transport [GO:0015031]; receptor catabolic process [GO:0032801] GO:0005768; GO:0010008; GO:0015031; GO:0030512; GO:0032801; GO:0034713; GO:0035091; GO:0043231; GO:0060394 17504 FUN_006751 92 116 49 140 251 ptg000001l:16204883-16207971 Q9UJV9 4.92e-87 Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog) Homo sapiens (Human) apoptotic process [GO:0006915]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005681; GO:0005829; GO:0006915; GO:0008283; GO:0016020; GO:0016887; GO:0030154; GO:0046872; GO:0071013 17505 FUN_015060 93 64 55 65 69 NA NA NA NA NA NA NA 17506 FUN_023619 1121 721 525 1748 1185 NA NA NA NA NA NA NA 17507 FUN_015061 910 1270 1416 612 488 NA NA NA NA NA NA NA 17508 FUN_006659 19 82 0 29 23 NA NA NA NA NA NA NA 17509 FUN_028940 6124 5914 2926 2438 3044 NA NA NA NA NA NA NA 17510 FUN_015064 2645 2478 1667 1400 1545 ptg000009l:5728983-5730913 A7STV9 1.5e-29 Structure-specific endonuclease subunit SLX1 homolog (EC 3.1.-.-) Nematostella vectensis (Starlet sea anemone) double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0008821; GO:0017108; GO:0033557; GO:0046872 17511 FUN_015065 22073 25254 17040 23073 19170 ptg000009l:5731387-5733212 Q8K3J1 2.05e-29 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979] GO:0003954; GO:0005739; GO:0005747; GO:0006120; GO:0006979; GO:0008137; GO:0009060; GO:0032981; GO:0042776; GO:0046872; GO:0051539 17512 FUN_015065 22073 25254 17040 23073 19170 ptg000009l:5731387-5733212 Q8K3J1 8.34e-23 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (EC 7.1.1.2) (Complex I-23kD) (CI-23kD) (NADH-ubiquinone oxidoreductase 23 kDa subunit) Mus musculus (Mouse) aerobic respiration [GO:0009060]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776]; response to oxidative stress [GO:0006979] GO:0003954; GO:0005739; GO:0005747; GO:0006120; GO:0006979; GO:0008137; GO:0009060; GO:0032981; GO:0042776; GO:0046872; GO:0051539 17513 FUN_015066 635 310 263 421 204 NA NA NA NA NA NA NA 17514 FUN_015067 80 110 115 207 283 NA NA NA NA NA NA NA 17515 FUN_031535 228 260 524 1319 823 NA NA NA NA NA NA NA 17516 FUN_041432 90864 61042 53495 103560 57499 ptg000035l:3668301-3671771 A3FEM2 1.75e-55 Protein FEV (Protein Pet-1) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; hematopoietic stem cell differentiation [GO:0060218]; nervous system development [GO:0007399]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000981; GO:0005634; GO:0006355; GO:0006357; GO:0007399; GO:0030154; GO:0060218 17517 FUN_038644 108 143 31 54 178 NA NA NA NA NA NA NA 17518 FUN_041430 30 27 52 37 11 ptg000035l:3646780-3654725 Q62070 8.1e-23 Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; G1/S transition of mitotic cell cycle [GO:0000082]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of mitotic cell cycle [GO:0007346] GO:0000082; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0006915; GO:0007346; GO:0008285; GO:0008637; GO:0010508; GO:0016236; GO:0016239; GO:0032091; GO:0043066; GO:0043123; GO:0045893; GO:0046777; GO:0050821; GO:0106310 17519 FUN_041430 30 27 52 37 11 ptg000035l:3646780-3654725 Q62070 8.1e-23 Serine/threonine-protein kinase pim-2 (EC 2.7.11.1) Mus musculus (Mouse) apoptotic mitochondrial changes [GO:0008637]; apoptotic process [GO:0006915]; G1/S transition of mitotic cell cycle [GO:0000082]; macroautophagy [GO:0016236]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of protein binding [GO:0032091]; positive regulation of autophagy [GO:0010508]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of macroautophagy [GO:0016239]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of mitotic cell cycle [GO:0007346] GO:0000082; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0006915; GO:0007346; GO:0008285; GO:0008637; GO:0010508; GO:0016236; GO:0016239; GO:0032091; GO:0043066; GO:0043123; GO:0045893; GO:0046777; GO:0050821; GO:0106310 17520 FUN_026197 0 19 28 93 81 NA NA NA NA NA NA NA 17521 FUN_004440 457 328 228 252 306 NA NA NA NA NA NA NA 17522 FUN_004441 884 820 607 1052 455 ntLink_8:23257754-23260022 Q0P5N6 1.23e-44 ADP-ribosylation factor-like protein 16 Homo sapiens (Human) NA GO:0003924; GO:0005525; GO:0005737 17523 FUN_004442 2671 2069 1915 1890 1088 NA NA NA NA NA NA NA 17524 FUN_004443 1104 1079 1008 994 604 NA NA NA NA NA NA NA 17525 FUN_004444 937 539 969 738 735 NA NA NA NA NA NA NA 17526 FUN_004445 4954 5300 9324 42397 11275 NA NA NA NA NA NA NA 17527 FUN_004446 541 481 1074 620 701 NA NA NA NA NA NA NA 17528 FUN_004447 3151 1566 1955 2886 2757 ntLink_8:23309399-23348186 B1AY13 9.24e-26 Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) Mus musculus (Mouse) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 17529 FUN_004447 3151 1566 1955 2886 2757 ntLink_8:23309399-23348186 B1AY13 9.24e-26 Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) Mus musculus (Mouse) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 17530 FUN_004447 3151 1566 1955 2886 2757 ntLink_8:23309399-23348186 B1AY13 3.43e-21 Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) Mus musculus (Mouse) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 17531 FUN_004447 3151 1566 1955 2886 2757 ntLink_8:23309399-23348186 B1AY13 5.47e-21 Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) Mus musculus (Mouse) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 17532 FUN_004448 1563 1055 932 1239 1323 ntLink_8:23352209-23363113 Q7Z2K6 1.48e-41 Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina) Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum unfolded protein response [GO:0030968]; proteolysis [GO:0006508] GO:0005783; GO:0005789; GO:0006508; GO:0008235; GO:0016020; GO:0030968; GO:0034599; GO:0046872 17533 FUN_004448 1563 1055 932 1239 1323 ntLink_8:23352209-23363113 Q7Z2K6 4.5e-24 Endoplasmic reticulum metallopeptidase 1 (EC 3.4.-.-) (Felix-ina) Homo sapiens (Human) cellular response to oxidative stress [GO:0034599]; endoplasmic reticulum unfolded protein response [GO:0030968]; proteolysis [GO:0006508] GO:0005783; GO:0005789; GO:0006508; GO:0008235; GO:0016020; GO:0030968; GO:0034599; GO:0046872 17534 FUN_004449 973 966 657 1042 667 NA NA NA NA NA NA NA 17535 FUN_002727 930 1044 11 4284 705 NA NA NA NA NA NA NA 17536 FUN_007930 735 1209 103 2175 554 NA NA NA NA NA NA NA 17537 FUN_002725 1143 1345 603 1076 852 NA NA NA NA NA NA NA 17538 FUN_028793 857 354 88 358 45 NA NA NA NA NA NA NA 17539 FUN_007935 13 10 0 0 0 NA NA NA NA NA NA NA 17540 FUN_007934 809 1203 833 507 727 NA NA NA NA NA NA NA 17541 FUN_002721 897 1052 516 813 863 NA NA NA NA NA NA NA 17542 FUN_007936 1476 1225 575 1471 874 NA NA NA NA NA NA NA 17543 FUN_007939 1479 1313 685 1148 913 NA NA NA NA NA NA NA 17544 FUN_002729 349 104 93 445 107 NA NA NA NA NA NA NA 17545 FUN_002728 682 815 74 1907 272 NA NA NA NA NA NA NA 17546 FUN_001191 588 380 378 502 426 NA NA NA NA NA NA NA 17547 FUN_001190 2674 1818 1633 2341 1816 ntLink_6:9609961-9631743 Q5R4F4 1.87e-33 Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0005789; GO:0006888; GO:0015031; GO:0030127; GO:0030134; GO:0070971 17548 FUN_001190 2674 1818 1633 2341 1816 ntLink_6:9609961-9631743 Q5R4F4 5.7e-22 Protein transport protein Sec31A (SEC31-like protein 1) (SEC31-related protein A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; protein transport [GO:0015031] GO:0005789; GO:0006888; GO:0015031; GO:0030127; GO:0030134; GO:0070971 17549 FUN_001193 466 235 427 1052 1007 ntLink_6:9656694-9658346 G3M4F8 8.62e-51 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 17550 FUN_001192 985 589 344 982 577 NA NA NA NA NA NA NA 17551 FUN_001195 101 207 140 198 200 NA NA NA NA NA NA NA 17552 FUN_001194 3 11 36 0 5 NA NA NA NA NA NA NA 17553 FUN_001197 812 269 387 460 554 NA NA NA NA NA NA NA 17554 FUN_001199 244 207 123 248 367 NA NA NA NA NA NA NA 17555 FUN_001198 1217 1071 881 1033 715 NA NA NA NA NA NA NA 17556 FUN_041437 85 0 0 40 99 NA NA NA NA NA NA NA 17557 FUN_025838 1470 580 463 660 948 ptg000020l:1171125-1178104 A0A1L8F5J9 1.39e-31 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 17558 FUN_025839 75 4 36 0 54 NA NA NA NA NA NA NA 17559 FUN_025834 20 106 36 19 31 NA NA NA NA NA NA NA 17560 FUN_025835 175 173 264 281 292 ptg000020l:1145490-1149052 Q64417 6.35e-38 Cytochrome P450 3A14 (EC 1.14.14.1) (CYPIIIA14) Cavia porcellus (Guinea pig) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 17561 FUN_025836 458 70 493 431 402 ptg000020l:1150773-1160694 Q1LVN8 4.54e-24 Protein adenylyltransferase SelO-1, mitochondrial (EC 2.7.7.108) (Selenoprotein O) (SelO) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005739; GO:0016779; GO:0046872 17562 FUN_025837 152 86 70 138 348 NA NA NA NA NA NA NA 17563 FUN_025830 0 38 3 48 3 NA NA NA NA NA NA NA 17564 FUN_025831 129 266 54 442 11 ptg000020l:1115003-1118281 Q7RTR2 1.76e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 17565 FUN_025832 21 0 17 54 18 NA NA NA NA NA NA NA 17566 FUN_025833 0 0 0 7 0 NA NA NA NA NA NA NA 17567 FUN_026192 400 348 202 181 259 ptg000020l:5803944-5807465 Q2HJD7 2.5e-36 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) Bos taurus (Bovine) valine catabolic process [GO:0006574] GO:0005739; GO:0006574; GO:0008442; GO:0016616; GO:0050661; GO:0051287 17568 FUN_038647 50 8 27 14 0 ptg000027l:9767709-9771541 Q1LYL8 3.3e-35 Protein asteroid homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 17569 FUN_035840 134526 98490 60363 151731 94028 NA NA NA NA NA NA NA 17570 FUN_035841 46069 44449 23441 75499 68308 NA NA NA NA NA NA NA 17571 FUN_035842 43 54 17 36 29 NA NA NA NA NA NA NA 17572 FUN_035843 1783 1929 929 1977 1574 NA NA NA NA NA NA NA 17573 FUN_035844 36907 30179 13851 20805 10355 NA NA NA NA NA NA NA 17574 FUN_035845 74 58 76 121 87 NA NA NA NA NA NA NA 17575 FUN_035846 873 892 965 1491 1192 NA NA NA NA NA NA NA 17576 FUN_035847 1104 655 800 1209 1089 NA NA NA NA NA NA NA 17577 FUN_035848 32 30 0 0 28 NA NA NA NA NA NA NA 17578 FUN_035849 9247 6111 3420 7959 7255 ptg000025l:12507087-12512002 Q9VQ29 1.12e-47 NA NA NA NA 17579 FUN_028796 24 0 0 0 0 NA NA NA NA NA NA NA 17580 FUN_018279 45 19 22 0 0 NA NA NA NA NA NA NA 17581 FUN_018272 86 0 61 82 42 NA NA NA NA NA NA NA 17582 FUN_018273 159 215 92 300 300 ptg000012l:6946114-6965657 Q96AY4 1.01e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17583 FUN_018273 159 215 92 300 300 ptg000012l:6946114-6965657 Q96AY4 1.51e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17584 FUN_018273 159 215 92 300 300 ptg000012l:6946114-6965657 Q96AY4 2.09e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17585 FUN_018273 159 215 92 300 300 ptg000012l:6946114-6965657 Q96AY4 3.21e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17586 FUN_018273 159 215 92 300 300 ptg000012l:6946114-6965657 Q96AY4 2.32e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17587 FUN_018270 0 0 0 34 0 NA NA NA NA NA NA NA 17588 FUN_018271 370 48 73 72 23 ptg000012l:6906408-6914271 Q9Y6N7 2.45e-22 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 17589 FUN_018277 128 31 10 126 43 NA NA NA NA NA NA NA 17590 FUN_018274 91 14 36 94 29 NA NA NA NA NA NA NA 17591 FUN_018275 19 11 35 28 28 NA NA NA NA NA NA NA 17592 FUN_040970 0 0 2 0 12 NA NA NA NA NA NA NA 17593 FUN_040971 1832 2692 1061 1763 2362 NA NA NA NA NA NA NA 17594 FUN_040972 6 5 4 5 0 ptg000033l:736829-738223 P81274 2.12e-22 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 17595 FUN_040973 228 129 52 299 119 NA NA NA NA NA NA NA 17596 FUN_040974 373 138 181 728 368 NA NA NA NA NA NA NA 17597 FUN_040976 4 1 2 11 15 NA NA NA NA NA NA NA 17598 FUN_040979 0 0 12 0 78 NA NA NA NA NA NA NA 17599 FUN_041438 1005 1033 656 813 586 NA NA NA NA NA NA NA 17600 FUN_003138 0 0 0 0 7 NA NA NA NA NA NA NA 17601 FUN_003135 0 0 0 0 9 NA NA NA NA NA NA NA 17602 FUN_003134 30 24 20 175 20 NA NA NA NA NA NA NA 17603 FUN_003137 0 0 0 0 8 NA NA NA NA NA NA NA 17604 FUN_003136 47 55 76 354 163 NA NA NA NA NA NA NA 17605 FUN_028020 134 589 211 305 258 NA NA NA NA NA NA NA 17606 FUN_028021 940 932 715 1107 527 NA NA NA NA NA NA NA 17607 FUN_028022 269 156 125 61 85 ptg000021l:14984084-14990512 A1L1W9 2.86e-27 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 17608 FUN_028023 1057 636 490 857 1061 NA NA NA NA NA NA NA 17609 FUN_028024 1200 773 717 852 1289 NA NA NA NA NA NA NA 17610 FUN_028025 255 121 338 269 370 NA NA NA NA NA NA NA 17611 FUN_028026 0 23 38 35 43 NA NA NA NA NA NA NA 17612 FUN_028027 1881 1476 880 3546 1829 NA NA NA NA NA NA NA 17613 FUN_028028 3350 2204 2329 4471 683 NA NA NA NA NA NA NA 17614 FUN_028029 49934 32709 20612 30184 10477 NA NA NA NA NA NA NA 17615 FUN_023293 7 1338 412 311 120 NA NA NA NA NA NA NA 17616 FUN_043058 0 0 0 0 31 NA NA NA NA NA NA NA 17617 FUN_043401 453 687 379 377 525 NA NA NA NA NA NA NA 17618 FUN_043400 1484 1149 825 914 1083 ptg000047l:7962285-7970002 Q10713 1.34e-24 Mitochondrial-processing peptidase subunit alpha (Alpha-MPP) (Inactive zinc metalloprotease alpha) (P-55) Homo sapiens (Human) protein processing involved in protein targeting to mitochondrion [GO:0006627] GO:0004222; GO:0005615; GO:0005739; GO:0005743; GO:0006627; GO:0017087; GO:0046872 17619 FUN_043403 1253 610 529 939 651 NA NA NA NA NA NA NA 17620 FUN_043402 1599 1160 865 813 636 NA NA NA NA NA NA NA 17621 FUN_043404 65 19 65 35 39 NA NA NA NA NA NA NA 17622 FUN_043407 0 0 0 22 8 NA NA NA NA NA NA NA 17623 FUN_043406 97 11 0 141 54 ptg000047l:8092976-8094155 P17124 7.59e-22 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 17624 FUN_043409 317 203 178 64 151 ptg000047l:8136853-8138571 G3M4F8 4.7e-36 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 17625 FUN_043408 21 20 4 0 0 ptg000047l:8126228-8128045 P07700 7.74e-30 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 17626 FUN_041312 1958 3538 1181 2415 2180 NA NA NA NA NA NA NA 17627 FUN_041310 1858 2194 903 2664 2157 NA NA NA NA NA NA NA 17628 FUN_041316 6 0 0 8 0 NA NA NA NA NA NA NA 17629 FUN_041315 55 0 0 41 5 NA NA NA NA NA NA NA 17630 FUN_041314 58 34 0 0 23 NA NA NA NA NA NA NA 17631 FUN_043050 71 0 22 25 0 NA NA NA NA NA NA NA 17632 FUN_011531 0 0 32 0 3 NA NA NA NA NA NA NA 17633 FUN_002266 0 0 0 10 12 NA NA NA NA NA NA NA 17634 FUN_002265 0 0 0 0 6 NA NA NA NA NA NA NA 17635 FUN_002269 14 1 5 1 40 NA NA NA NA NA NA NA 17636 FUN_043057 7 0 0 0 6 NA NA NA NA NA NA NA 17637 FUN_043054 37 21 8 62 37 ptg000047l:3519476-3520777 Q80XJ3 1.55e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 17638 FUN_043128 269 186 223 132 300 ptg000047l:4419176-4421742 Q28C91 8.58e-37 Ethylmalonyl-CoA decarboxylase (EC 4.1.1.94) (Enoyl-CoA hydratase domain-containing protein 1) (Methylmalonyl-CoA decarboxylase) (MMCD) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0004492; GO:0005829; GO:0016831 17639 FUN_006527 461 532 442 656 574 NA NA NA NA NA NA NA 17640 FUN_022707 365 64 164 211 343 NA NA NA NA NA NA NA 17641 FUN_022706 271 165 199 220 508 NA NA NA NA NA NA NA 17642 FUN_022705 60526 52457 15608 28190 32288 NA NA NA NA NA NA NA 17643 FUN_022704 339 486 116 311 643 ptg000016l:12503864-12506144 F6NXI9 3.51e-79 NA NA NA NA 17644 FUN_022704 339 486 116 311 643 ptg000016l:12503864-12506144 F6NXI9 4.82e-23 NA NA NA NA 17645 FUN_022703 6734 4853 4017 4542 5365 ptg000016l:12500506-12501338 P11233 2.69e-68 Ras-related protein Ral-A (EC 3.6.5.2) Homo sapiens (Human) actin cytoskeleton reorganization [GO:0031532]; cell cycle [GO:0007049]; cell division [GO:0051301]; chemotaxis [GO:0006935]; establishment of protein localization to mitochondrion [GO:0072655]; exocytosis [GO:0006887]; membrane raft localization [GO:0051665]; neural tube closure [GO:0001843]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of mitochondrial fission [GO:0090141]; Ras protein signal transduction [GO:0007265]; receptor internalization [GO:0031623]; regulation of exocytosis [GO:0017157]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; signal transduction [GO:0007165] GO:0001843; GO:0003924; GO:0003925; GO:0005525; GO:0005739; GO:0005886; GO:0005925; GO:0006887; GO:0006935; GO:0007049; GO:0007165; GO:0007265; GO:0009986; GO:0017022; GO:0017157; GO:0019003; GO:0030659; GO:0031532; GO:0031623; GO:0031625; GO:0031755; GO:0032154; GO:0045742; GO:0051117; GO:0051301; GO:0051491; GO:0051665; GO:0070062; GO:0072655; GO:0090141; GO:0090543; GO:0097060; GO:0098685; GO:0099149 17646 FUN_022702 2046 1607 1463 1949 2279 ptg000016l:12489782-12497808 Q3MJK5 7.49e-25 Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (Protein kinase for splicing component) Rattus norvegicus (Rat) mRNA processing [GO:0006397]; negative regulation of stem cell differentiation [GO:2000737]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of MAP kinase activity [GO:0043405]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; transcription by RNA polymerase II [GO:0006366]; transcription elongation by RNA polymerase II promoter [GO:0006368] GO:0000307; GO:0002944; GO:0004672; GO:0004693; GO:0005524; GO:0005634; GO:0006366; GO:0006368; GO:0006397; GO:0006468; GO:0008024; GO:0008353; GO:0008380; GO:0016607; GO:0019901; GO:0019908; GO:0030332; GO:0032968; GO:0043405; GO:0043484; GO:0046777; GO:0070816; GO:0106310; GO:2000737 17647 FUN_022701 257 276 128 222 236 NA NA NA NA NA NA NA 17648 FUN_022700 2163 2324 1020 1123 1199 ptg000016l:12481041-12486111 O89112 2.45e-22 Glutathione S-transferase LANCL1 (EC 2.5.1.18) (40 kDa erythrocyte membrane protein) (p40) (LanC-like protein 1) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; peptide modification [GO:0031179]; regulation of neuron apoptotic process [GO:0043523]; regulation of oxidative stress-induced neuron death [GO:1903203] GO:0004364; GO:0005737; GO:0005886; GO:0005975; GO:0008270; GO:0017124; GO:0031179; GO:0043295; GO:0043523; GO:0050750; GO:1903203 17649 FUN_022709 299 90 112 148 233 NA NA NA NA NA NA NA 17650 FUN_022708 112 170 104 193 245 ptg000016l:12524633-12528014 P79782 2.57e-25 Transcription factor 15 (TCF-15) (Paraxis) (Protein bHLH-EC2) Gallus gallus (Chicken) cell differentiation [GO:0030154]; developmental process [GO:0032502]; negative regulation of hematopoietic stem cell differentiation [GO:1902037]; positive regulation of stem cell differentiation [GO:2000738]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0019827; GO:0030154; GO:0032502; GO:0045944; GO:0046983; GO:0070888; GO:1902037; GO:2000738 17651 FUN_008764 1930 287 604 1145 287 NA NA NA NA NA NA NA 17652 FUN_026094 516 452 256 572 577 NA NA NA NA NA NA NA 17653 FUN_023392 976 486 334 623 837 NA NA NA NA NA NA NA 17654 FUN_042468 9 0 0 0 4 NA NA NA NA NA NA NA 17655 FUN_042469 0 0 0 0 7 NA NA NA NA NA NA NA 17656 FUN_042462 1 0 4 0 7 NA NA NA NA NA NA NA 17657 FUN_042467 0 0 6 0 0 NA NA NA NA NA NA NA 17658 FUN_040191 0 0 27 4 103 NA NA NA NA NA NA NA 17659 FUN_040196 69 42 24 108 7 NA NA NA NA NA NA NA 17660 FUN_040197 16 0 15 26 11 NA NA NA NA NA NA NA 17661 FUN_040194 0 25 0 0 0 NA NA NA NA NA NA NA 17662 FUN_040195 0 0 0 0 6 NA NA NA NA NA NA NA 17663 FUN_032188 65 16 0 0 24 NA NA NA NA NA NA NA 17664 FUN_029867 0 10 0 0 0 NA NA NA NA NA NA NA 17665 FUN_032181 0 0 0 0 112 NA NA NA NA NA NA NA 17666 FUN_032456 110 59 152 145 189 ptg000023l:32132960-32140081 E9Q236 1.84e-76 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17667 FUN_032456 110 59 152 145 189 ptg000023l:32132960-32140081 E9Q236 1.65e-53 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17668 FUN_032456 110 59 152 145 189 ptg000023l:32132960-32140081 E9Q236 7.36e-36 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17669 FUN_032457 21 0 0 12 32 NA NA NA NA NA NA NA 17670 FUN_032454 0 8 0 12 0 ptg000023l:32126657-32127158 O15439 1.65e-29 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 17671 FUN_032455 10 0 17 5 51 NA NA NA NA NA NA NA 17672 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 1.81e-74 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17673 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 3.88e-74 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17674 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 4.71e-56 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17675 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 1.18e-55 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17676 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 1.57e-39 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17677 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 1.57e-39 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17678 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 6.12e-31 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17679 FUN_032452 1757 570 566 585 867 ptg000023l:32089694-32112799 E9Q236 4.12e-29 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17680 FUN_032453 1192 433 574 513 521 ptg000023l:32118027-32124575 E9Q236 3.66e-77 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17681 FUN_032453 1192 433 574 513 521 ptg000023l:32118027-32124575 E9Q236 1.03e-54 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17682 FUN_032453 1192 433 574 513 521 ptg000023l:32118027-32124575 E9Q236 9.22e-30 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17683 FUN_032450 88 22 36 8 40 ptg000023l:32080538-32081643 O15439 6.98e-62 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 17684 FUN_032451 6 0 3 0 0 NA NA NA NA NA NA NA 17685 FUN_032458 165 89 168 151 208 ptg000023l:32142135-32148830 E9Q236 2.75e-76 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17686 FUN_032458 165 89 168 151 208 ptg000023l:32142135-32148830 E9Q236 1.63e-58 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17687 FUN_032458 165 89 168 151 208 ptg000023l:32142135-32148830 E9Q236 3.87e-29 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 17688 FUN_032459 8884 9798 8858 9358 4665 NA NA NA NA NA NA NA 17689 FUN_023890 25 32 1 27 19 NA NA NA NA NA NA NA 17690 FUN_023894 6 0 0 0 24 NA NA NA NA NA NA NA 17691 FUN_000248 853 1024 434 758 650 NA NA NA NA NA NA NA 17692 FUN_000242 2558 2253 1089 1855 1170 ntLink_6:686674-691171 Q6P832 1.03e-46 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine biosynthetic process [GO:0006601] GO:0005743; GO:0006601; GO:0015068 17693 FUN_000242 2558 2253 1089 1855 1170 ntLink_6:686674-691171 Q6P832 5.83e-32 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) creatine biosynthetic process [GO:0006601] GO:0005743; GO:0006601; GO:0015068 17694 FUN_000243 2572 1537 1790 2837 1984 NA NA NA NA NA NA NA 17695 FUN_000240 3841 4046 3403 4384 2667 NA NA NA NA NA NA NA 17696 FUN_000246 9 20 5 0 80 NA NA NA NA NA NA NA 17697 FUN_000247 838 517 369 822 568 ntLink_6:725004-737538 P42111 1.82e-23 Uncharacterized protein YxaL Bacillus subtilis (strain 168) NA GO:0005576 17698 FUN_000244 0 26 49 0 102 ntLink_6:702936-706555 Q6PH19 1.85e-62 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Danio rerio (Zebrafish) (Brachydanio rerio) creatine biosynthetic process [GO:0006601] GO:0005739; GO:0005743; GO:0006601; GO:0015067; GO:0015068 17699 FUN_000244 0 26 49 0 102 ntLink_6:702936-706555 Q6PH19 1.85e-62 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Danio rerio (Zebrafish) (Brachydanio rerio) creatine biosynthetic process [GO:0006601] GO:0005739; GO:0005743; GO:0006601; GO:0015067; GO:0015068 17700 FUN_000244 0 26 49 0 102 ntLink_6:702936-706555 Q6PH19 5.98e-33 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Danio rerio (Zebrafish) (Brachydanio rerio) creatine biosynthetic process [GO:0006601] GO:0005739; GO:0005743; GO:0006601; GO:0015067; GO:0015068 17701 FUN_000244 0 26 49 0 102 ntLink_6:702936-706555 Q6PH19 1.71e-22 Glycine amidinotransferase, mitochondrial (EC 2.1.4.1) (L-arginine:glycine amidinotransferase) (Transamidinase) Danio rerio (Zebrafish) (Brachydanio rerio) creatine biosynthetic process [GO:0006601] GO:0005739; GO:0005743; GO:0006601; GO:0015067; GO:0015068 17702 FUN_000245 0 0 0 0 43 NA NA NA NA NA NA NA 17703 FUN_029139 1630 1047 530 1033 1201 NA NA NA NA NA NA NA 17704 FUN_029138 232 331 177 519 126 NA NA NA NA NA NA NA 17705 FUN_010713 658 509 246 521 389 NA NA NA NA NA NA NA 17706 FUN_029131 1684 2666 710 2953 2816 NA NA NA NA NA NA NA 17707 FUN_029130 1197 802 719 2342 1393 NA NA NA NA NA NA NA 17708 FUN_029133 52 35 45 53 78 NA NA NA NA NA NA NA 17709 FUN_029132 59 38 57 17 32 NA NA NA NA NA NA NA 17710 FUN_029135 619 509 346 606 455 NA NA NA NA NA NA NA 17711 FUN_029134 79 80 109 267 170 NA NA NA NA NA NA NA 17712 FUN_029137 8 1 4 16 2 NA NA NA NA NA NA NA 17713 FUN_029136 8440 5697 3185 10239 7620 NA NA NA NA NA NA NA 17714 FUN_006849 20 14 0 32 28 NA NA NA NA NA NA NA 17715 FUN_039364 16 0 8 6 0 NA NA NA NA NA NA NA 17716 FUN_024481 6779 2770 2980 5720 4524 NA NA NA NA NA NA NA 17717 FUN_039361 68 20 20 0 47 ptg000029c:506034-520193 Q8RLU1 2.19e-34 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 17718 FUN_039361 68 20 20 0 47 ptg000029c:506034-520193 Q8RLU1 2.19e-34 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 17719 FUN_039360 350 61 60 382 61 NA NA NA NA NA NA NA 17720 FUN_039363 548 414 193 359 283 ptg000029c:551963-630229 Q99315 4.55e-72 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 17721 FUN_039362 114 37 46 59 140 NA NA NA NA NA NA NA 17722 FUN_006966 4113 682 127 666 159 ptg000001l:18831151-18834521 Q9U6Y6 1.12e-29 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 17723 FUN_006966 4113 682 127 666 159 ptg000001l:18831151-18834521 Q9U6Y6 1.79e-26 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 17724 FUN_012411 675 558 288 502 503 NA NA NA NA NA NA NA 17725 FUN_010719 15563 9699 5163 9526 7839 NA NA NA NA NA NA NA 17726 FUN_010718 300 160 109 122 124 NA NA NA NA NA NA NA 17727 FUN_015949 54 9 23 0 20 NA NA NA NA NA NA NA 17728 FUN_015948 0 0 10 0 0 NA NA NA NA NA NA NA 17729 FUN_010711 1807 1496 1020 1595 1449 NA NA NA NA NA NA NA 17730 FUN_010710 0 14 12 19 27 NA NA NA NA NA NA NA 17731 FUN_010717 5975 5951 3373 4447 2365 ptg000007l:2069669-2075404 P42688 1.59e-100 Tyrosine-protein kinase SRK2 (EC 2.7.10.2) Spongilla lacustris (Freshwater sponge) NA GO:0004715; GO:0005524; GO:0005737 17732 FUN_010716 2764 1821 986 1910 1317 ptg000007l:2064132-2068083 P42688 5.58e-94 Tyrosine-protein kinase SRK2 (EC 2.7.10.2) Spongilla lacustris (Freshwater sponge) NA GO:0004715; GO:0005524; GO:0005737 17733 FUN_010716 2764 1821 986 1910 1317 ptg000007l:2064132-2068083 P42688 3.89e-55 Tyrosine-protein kinase SRK2 (EC 2.7.10.2) Spongilla lacustris (Freshwater sponge) NA GO:0004715; GO:0005524; GO:0005737 17734 FUN_012623 0 0 0 0 25 NA NA NA NA NA NA NA 17735 FUN_012622 2 16 10 36 19 NA NA NA NA NA NA NA 17736 FUN_012621 7 0 0 0 20 NA NA NA NA NA NA NA 17737 FUN_012627 0 22 0 3 7 NA NA NA NA NA NA NA 17738 FUN_012626 3 11 0 0 5 NA NA NA NA NA NA NA 17739 FUN_012625 16 0 13 0 117 NA NA NA NA NA NA NA 17740 FUN_012624 1178 1808 922 1436 1085 ptg000008l:10608617-10613786 Q99J27 8.37e-53 Acetyl-coenzyme A transporter 1 (AT-1) (Acetyl-CoA transporter 1) (Solute carrier family 33 member 1) Mus musculus (Mouse) NA GO:0005789; GO:0008521; GO:0015295 17741 FUN_012628 685 343 620 399 1058 ptg000008l:10650893-10660610 Q4ZJI4 8.28e-26 Sodium/hydrogen exchanger 9B1 (Na(+)/H(+) exchanger-like domain-containing protein 1) (NHE domain-containing protein 1) (Sodium/hydrogen exchanger-like domain-containing protein 1) (Solute carrier family 9, subfamily B member 1) Homo sapiens (Human) flagellated sperm motility [GO:0030317]; ion transmembrane transport [GO:0034220]; regulation of intracellular pH [GO:0051453]; single fertilization [GO:0007338] GO:0005886; GO:0007338; GO:0015385; GO:0030317; GO:0034220; GO:0051453; GO:0097228 17742 FUN_038979 24 0 0 0 0 NA NA NA NA NA NA NA 17743 FUN_038971 46 40 39 0 106 NA NA NA NA NA NA NA 17744 FUN_038970 2 6 5 2 17 NA NA NA NA NA NA NA 17745 FUN_025928 469 233 301 372 546 NA NA NA NA NA NA NA 17746 FUN_009538 1407 1138 861 798 430 NA NA NA NA NA NA NA 17747 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 5.83e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17748 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 2.94e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17749 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 1.77e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17750 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 6.89e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17751 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 2.24e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17752 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 1.04e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17753 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 3.68e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17754 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 4.37e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17755 FUN_009537 559 489 193 566 233 ptg000004l:8237398-8240437 Q96AY4 2.23e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17756 FUN_025924 5949 3749 7657 5933 5511 NA NA NA NA NA NA NA 17757 FUN_027982 3084 1928 1873 2661 2313 NA NA NA NA NA NA NA 17758 FUN_027983 4605 3063 1621 3693 2063 ptg000021l:14200905-14206170 Q0MVN8 7.3e-21 Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) Sus scrofa (Pig) xenobiotic catabolic process [GO:0042178] GO:0003730; GO:0003960; GO:0005829; GO:0008270; GO:0042178; GO:0070402 17759 FUN_027980 149 125 51 51 100 NA NA NA NA NA NA NA 17760 FUN_009534 82 0 40 86 67 NA NA NA NA NA NA NA 17761 FUN_027986 540 796 343 485 145 NA NA NA NA NA NA NA 17762 FUN_027987 52 6808 2438 3038 4809 NA NA NA NA NA NA NA 17763 FUN_027984 8893 4700 6482 13998 10778 NA NA NA NA NA NA NA 17764 FUN_009533 992 1392 575 2176 922 NA NA NA NA NA NA NA 17765 FUN_027988 36 4344 2024 2922 5201 NA NA NA NA NA NA NA 17766 FUN_027989 89 13165 7630 6757 8589 NA NA NA NA NA NA NA 17767 FUN_025923 1573 757 2809 1631 1231 NA NA NA NA NA NA NA 17768 FUN_009531 1705 883 816 670 833 NA NA NA NA NA NA NA 17769 FUN_006846 1000 1594 1144 1911 1758 ptg000001l:17311167-17312987 Q6AYU1 4.39e-71 Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; fibroblast proliferation [GO:0048144]; histone acetylation [GO:0016573]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of cell cycle [GO:0051726] GO:0000123; GO:0000724; GO:0000786; GO:0003682; GO:0006325; GO:0008283; GO:0016573; GO:0016575; GO:0016580; GO:0035267; GO:0043967; GO:0043968; GO:0045893; GO:0047485; GO:0048144; GO:0051726; GO:1905168 17770 FUN_006846 1000 1594 1144 1911 1758 ptg000001l:17311167-17312987 Q6AYU1 7.29e-30 Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; double-strand break repair via homologous recombination [GO:0000724]; fibroblast proliferation [GO:0048144]; histone acetylation [GO:0016573]; histone deacetylation [GO:0016575]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; regulation of cell cycle [GO:0051726] GO:0000123; GO:0000724; GO:0000786; GO:0003682; GO:0006325; GO:0008283; GO:0016573; GO:0016575; GO:0016580; GO:0035267; GO:0043967; GO:0043968; GO:0045893; GO:0047485; GO:0048144; GO:0051726; GO:1905168 17771 FUN_009530 255 509 245 504 598 NA NA NA NA NA NA NA 17772 FUN_014706 2532 1985 1453 2133 2040 ptg000009l:2310395-2313310 Q8IZJ6 5.4e-44 Inactive L-threonine 3-dehydrogenase, mitochondrial (Short chain dehydrogenase/reductase family 14E member 1 pseudogene) Homo sapiens (Human) threonine catabolic process [GO:0006567] GO:0005743; GO:0006567; GO:0008743 17773 FUN_015440 254 59 25 143 232 NA NA NA NA NA NA NA 17774 FUN_014704 8307 13726 6272 8127 5572 NA NA NA NA NA NA NA 17775 FUN_014705 3330 5759 2445 3364 2782 NA NA NA NA NA NA NA 17776 FUN_014702 3485 3613 1970 2302 2524 NA NA NA NA NA NA NA 17777 FUN_014703 30 57 0 51 50 NA NA NA NA NA NA NA 17778 FUN_014700 116 103 0 0 81 NA NA NA NA NA NA NA 17779 FUN_014701 725 371 452 710 735 NA NA NA NA NA NA NA 17780 FUN_022839 392 26 0 44 0 ptg000017l:535065-557452 Q95SX7 1.14e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 17781 FUN_014708 128 98 85 259 167 ptg000009l:2323993-2325534 O14088 6.97e-38 Uncharacterized oxidoreductase C2F3.05c (EC 1.-.-.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) arabinose catabolic process [GO:0019568]; D-xylose catabolic process [GO:0042843] GO:0005634; GO:0005829; GO:0019568; GO:0032866; GO:0032867; GO:0042843 17782 FUN_014709 3052 2298 902 1939 1701 NA NA NA NA NA NA NA 17783 FUN_012419 11890 10222 7725 8036 5442 NA NA NA NA NA NA NA 17784 FUN_022838 1536 1020 741 1025 820 NA NA NA NA NA NA NA 17785 FUN_017898 405 257 439 512 508 NA NA NA NA NA NA NA 17786 FUN_026589 1414 2514 1720 1565 4002 NA NA NA NA NA NA NA 17787 FUN_026588 1612 1938 1012 2024 1598 NA NA NA NA NA NA NA 17788 FUN_026581 17 43 0 9 7 NA NA NA NA NA NA NA 17789 FUN_026580 0 0 10 16 13 NA NA NA NA NA NA NA 17790 FUN_026583 1726 647 811 849 1134 NA NA NA NA NA NA NA 17791 FUN_026582 2095 1086 1169 2059 2460 NA NA NA NA NA NA NA 17792 FUN_026585 1223 913 656 560 1669 NA NA NA NA NA NA NA 17793 FUN_026584 25 5 0 6 87 NA NA NA NA NA NA NA 17794 FUN_026587 814 1793 500 1222 152 NA NA NA NA NA NA NA 17795 FUN_028430 0 0 0 68 0 NA NA NA NA NA NA NA 17796 FUN_035819 3566 2348 1848 2110 887 ptg000025l:12089700-12100614 P16423 9.58e-22 Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM (Retrovirus-related Pol polyprotein from type II retrotransposable element R2DM) [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) proteolysis [GO:0006508] GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0046872 17797 FUN_009223 66 167 91 57 196 NA NA NA NA NA NA NA 17798 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 5.39e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17799 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 1.29e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17800 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 1.02e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17801 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 1.31e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17802 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 1.02e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17803 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 1.11e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17804 FUN_009222 11 27 8 75 7 ptg000004l:4130954-4136832 Q96AY4 4.22e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17805 FUN_009220 31 0 0 59 12 NA NA NA NA NA NA NA 17806 FUN_009227 194 105 110 194 59 NA NA NA NA NA NA NA 17807 FUN_009226 60 36 16 62 0 ptg000004l:4168661-4172984 Q96AY4 1.22e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17808 FUN_009226 60 36 16 62 0 ptg000004l:4168661-4172984 Q96AY4 3.52e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17809 FUN_009226 60 36 16 62 0 ptg000004l:4168661-4172984 Q96AY4 5.92e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 17810 FUN_009225 76 21 58 59 23 NA NA NA NA NA NA NA 17811 FUN_009228 26 1026 1033 1457 0 ptg000004l:4194043-4250948 Q9NYQ7 4.53e-24 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 17812 FUN_026633 7 0 3 6 36 NA NA NA NA NA NA NA 17813 FUN_019255 0 0 0 0 12 NA NA NA NA NA NA NA 17814 FUN_026637 0 0 0 0 15 NA NA NA NA NA NA NA 17815 FUN_019250 0 0 0 0 26 NA NA NA NA NA NA NA 17816 FUN_026638 249 14 176 110 0 NA NA NA NA NA NA NA 17817 FUN_019259 505 451 222 440 634 NA NA NA NA NA NA NA 17818 FUN_025584 22673 17930 9549 16507 13556 NA NA NA NA NA NA NA 17819 FUN_025585 85 157 111 217 179 NA NA NA NA NA NA NA 17820 FUN_025586 0 86 0 133 0 NA NA NA NA NA NA NA 17821 FUN_025587 35 61 8 43 16 NA NA NA NA NA NA NA 17822 FUN_025580 1490 639 593 1146 1127 NA NA NA NA NA NA NA 17823 FUN_025581 29873 23856 13631 18644 18094 ptg000019l:4654991-4658496 Q95NI4 1.94e-45 Calmodulin (CaM) Halichondria okadai (Marine sponge) (Reniera okadai) NA GO:0005509 17824 FUN_025581 29873 23856 13631 18644 18094 ptg000019l:4654991-4658496 Q95NI4 2.38e-23 Calmodulin (CaM) Halichondria okadai (Marine sponge) (Reniera okadai) NA GO:0005509 17825 FUN_025582 14551 19270 10492 14300 9053 ptg000019l:4661129-4665118 Q8STF0 6.97e-46 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 17826 FUN_025582 14551 19270 10492 14300 9053 ptg000019l:4661129-4665118 Q8STF0 3.86e-23 Calmodulin (CaM) Strongylocentrotus intermedius (Sea urchin) NA GO:0005509 17827 FUN_025583 214 96 71 106 152 NA NA NA NA NA NA NA 17828 FUN_000418 769 333 312 775 499 ntLink_6:2727747-2734866 P24463 9.75e-25 Cytochrome P450 3A12 (EC 1.14.14.1) (CYPIIIA12) (Cytochrome P450-PBD-1) Canis lupus familiaris (Dog) (Canis familiaris) hormone metabolic process [GO:0042445]; organic hydroxy compound metabolic process [GO:1901615]; oxidative demethylation [GO:0070989]; progesterone metabolic process [GO:0042448]; steroid metabolic process [GO:0008202] GO:0004497; GO:0005506; GO:0005789; GO:0008202; GO:0008395; GO:0020037; GO:0042445; GO:0042448; GO:0050649; GO:0070330; GO:0070989; GO:1901615 17829 FUN_025588 7 5 0 0 10 NA NA NA NA NA NA NA 17830 FUN_025589 63 58 20 27 28 NA NA NA NA NA NA NA 17831 FUN_024675 843 854 488 1123 680 NA NA NA NA NA NA NA 17832 FUN_024677 1922 2124 1165 2044 2348 NA NA NA NA NA NA NA 17833 FUN_023512 59 3 20 9 36 ptg000017l:8418589-8421461 Q91175 8.53e-40 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 17834 FUN_024671 386 1036 203 592 547 NA NA NA NA NA NA NA 17835 FUN_024670 0 0 1 4 12 NA NA NA NA NA NA NA 17836 FUN_024673 2548 2635 1582 5298 3620 NA NA NA NA NA NA NA 17837 FUN_024672 463 211 82 599 320 NA NA NA NA NA NA NA 17838 FUN_024679 1143 984 730 1247 1263 ptg000018l:9819753-9823010 P91580 4.14e-42 Putative Ras-related protein Rab-33 Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis) Rab protein signal transduction [GO:0032482] GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005886; GO:0032482 17839 FUN_024678 14 1 5 5 5 NA NA NA NA NA NA NA 17840 FUN_023514 0 7 13 2 0 NA NA NA NA NA NA NA 17841 FUN_021009 0 0 32 0 120 NA NA NA NA NA NA NA 17842 FUN_026741 812 590 416 498 289 ptg000020l:12983749-12989228 Q9QZS6 2.14e-83 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 17843 FUN_021006 242 106 84 176 89 NA NA NA NA NA NA NA 17844 FUN_021000 0 3 10 1 22 NA NA NA NA NA NA NA 17845 FUN_018706 7 0 2 11 38 NA NA NA NA NA NA NA 17846 FUN_017979 3 0 6 0 41 NA NA NA NA NA NA NA 17847 FUN_018704 3 0 0 0 16 ptg000012l:12164050-12173011 P14381 9.72e-73 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 17848 FUN_018704 3 0 0 0 16 ptg000012l:12164050-12173011 P14381 9.72e-73 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 17849 FUN_017974 242 90 167 333 302 NA NA NA NA NA NA NA 17850 FUN_018708 0 0 0 0 78 NA NA NA NA NA NA NA 17851 FUN_017977 26 19 0 5 5 NA NA NA NA NA NA NA 17852 FUN_017970 2176 1503 1758 2918 1776 NA NA NA NA NA NA NA 17853 FUN_017971 47 27 0 0 6 NA NA NA NA NA NA NA 17854 FUN_017972 1250 1323 433 701 244 NA NA NA NA NA NA NA 17855 FUN_017973 88 10 75 79 168 NA NA NA NA NA NA NA 17856 FUN_013801 2 0 0 0 12 NA NA NA NA NA NA NA 17857 FUN_035535 1863 1302 1082 1422 1131 NA NA NA NA NA NA NA 17858 FUN_035536 3018 2661 1450 2031 1790 NA NA NA NA NA NA NA 17859 FUN_035530 13 0 0 7 9 NA NA NA NA NA NA NA 17860 FUN_035538 12 0 11 79 43 NA NA NA NA NA NA NA 17861 FUN_035539 490 197 283 697 465 ptg000025l:8770985-8798823 Q761V0 2.27e-43 Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) Mus musculus (Mouse) glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; neurotransmitter reuptake [GO:0098810]; neurotransmitter uptake [GO:0001504]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012] GO:0001504; GO:0005768; GO:0005886; GO:0015187; GO:0015375; GO:0015816; GO:0031045; GO:0035725; GO:0042734; GO:0046872; GO:0060012; GO:0098690; GO:0098810; GO:1903804 17862 FUN_035539 490 197 283 697 465 ptg000025l:8770985-8798823 Q761V0 5.05e-31 Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) Mus musculus (Mouse) glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; neurotransmitter reuptake [GO:0098810]; neurotransmitter uptake [GO:0001504]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012] GO:0001504; GO:0005768; GO:0005886; GO:0015187; GO:0015375; GO:0015816; GO:0031045; GO:0035725; GO:0042734; GO:0046872; GO:0060012; GO:0098690; GO:0098810; GO:1903804 17863 FUN_035539 490 197 283 697 465 ptg000025l:8770985-8798823 Q761V0 3.46e-24 Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) Mus musculus (Mouse) glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; neurotransmitter reuptake [GO:0098810]; neurotransmitter uptake [GO:0001504]; sodium ion transmembrane transport [GO:0035725]; synaptic transmission, glycinergic [GO:0060012] GO:0001504; GO:0005768; GO:0005886; GO:0015187; GO:0015375; GO:0015816; GO:0031045; GO:0035725; GO:0042734; GO:0046872; GO:0060012; GO:0098690; GO:0098810; GO:1903804 17864 FUN_006813 0 0 0 0 170 NA NA NA NA NA NA NA 17865 FUN_038115 365 235 752 477 302 NA NA NA NA NA NA NA 17866 FUN_038114 64 197 581 153 33 NA NA NA NA NA NA NA 17867 FUN_038117 2131 735 1034 1462 1320 ptg000027l:2735621-2760944 P49815 5.08e-26 Tuberin (Tuberous sclerosis 2 protein) Homo sapiens (Human) anoikis [GO:0043276]; endocytosis [GO:0006897]; heart development [GO:0007507]; insulin-like growth factor receptor signaling pathway [GO:0048009]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mitophagy [GO:1901525]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; negative regulation of Wnt signaling pathway [GO:0030178]; neural tube closure [GO:0001843]; positive chemotaxis [GO:0050918]; positive regulation of GTPase activity [GO:0043547]; positive regulation of macroautophagy [GO:0016239]; protein import into nucleus [GO:0006606]; protein kinase B signaling [GO:0043491]; protein localization [GO:0008104]; regulation of cell cycle [GO:0051726]; regulation of endocytosis [GO:0030100]; regulation of insulin receptor signaling pathway [GO:0046626]; regulation of small GTPase mediated signal transduction [GO:0051056]; vesicle-mediated transport [GO:0016192] GO:0001843; GO:0005096; GO:0005634; GO:0005737; GO:0005764; GO:0005794; GO:0005829; GO:0006469; GO:0006606; GO:0006897; GO:0007507; GO:0008104; GO:0008285; GO:0014067; GO:0014069; GO:0016020; GO:0016192; GO:0016239; GO:0019902; GO:0030100; GO:0030178; GO:0031267; GO:0032007; GO:0033596; GO:0042803; GO:0043276; GO:0043491; GO:0043547; GO:0046626; GO:0046627; GO:0048009; GO:0048471; GO:0050918; GO:0051056; GO:0051726; GO:0051879; GO:0051898; GO:1901525 17868 FUN_038116 2454 1204 1597 3520 2332 ptg000027l:2554869-2638171 Q9BYK8 4.67e-56 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 17869 FUN_038116 2454 1204 1597 3520 2332 ptg000027l:2554869-2638171 Q9BYK8 2.2e-51 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 17870 FUN_038116 2454 1204 1597 3520 2332 ptg000027l:2554869-2638171 Q9BYK8 2.2e-51 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 17871 FUN_038111 3 1025 3019 17 209 ptg000027l:2514119-2517245 C6FG12 1.78e-26 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 17872 FUN_038110 4 916 600 0 95 NA NA NA NA NA NA NA 17873 FUN_038113 0 335 209 0 0 NA NA NA NA NA NA NA 17874 FUN_038112 0 178 84 0 0 NA NA NA NA NA NA NA 17875 FUN_038119 23 57 0 0 13 NA NA NA NA NA NA NA 17876 FUN_038118 498 372 387 280 336 NA NA NA NA NA NA NA 17877 FUN_018181 20 0 22 62 32 NA NA NA NA NA NA NA 17878 FUN_021918 0 0 2 0 7 NA NA NA NA NA NA NA 17879 FUN_008336 119 120 120 110 139 NA NA NA NA NA NA NA 17880 FUN_039648 0 0 20 0 6 NA NA NA NA NA NA NA 17881 FUN_008337 74 84 59 84 151 NA NA NA NA NA NA NA 17882 FUN_039642 6 0 26 2 132 NA NA NA NA NA NA NA 17883 FUN_039643 0 0 0 0 23 NA NA NA NA NA NA NA 17884 FUN_039640 0 0 45 28 37 NA NA NA NA NA NA NA 17885 FUN_039641 0 0 9 0 0 NA NA NA NA NA NA NA 17886 FUN_039646 5 0 0 45 0 NA NA NA NA NA NA NA 17887 FUN_039647 4 0 10 0 17 NA NA NA NA NA NA NA 17888 FUN_039644 0 0 27 0 23 NA NA NA NA NA NA NA 17889 FUN_037978 1334 1449 951 816 626 NA NA NA NA NA NA NA 17890 FUN_037979 8390 7245 5605 7128 5866 ptg000027l:1135631-1138752 P51570 2.48e-39 Galactokinase (EC 2.7.1.6) (Galactose kinase) Homo sapiens (Human) galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] GO:0004335; GO:0005524; GO:0005534; GO:0005737; GO:0005829; GO:0006012; GO:0016020; GO:0019388; GO:0019402; GO:0033499; GO:0061623; GO:0070062 17891 FUN_037979 8390 7245 5605 7128 5866 ptg000027l:1135631-1138752 P51570 6.13e-32 Galactokinase (EC 2.7.1.6) (Galactose kinase) Homo sapiens (Human) galactitol metabolic process [GO:0019402]; galactose catabolic process [GO:0019388]; galactose catabolic process via UDP-galactose [GO:0033499]; galactose metabolic process [GO:0006012]; glycolytic process from galactose [GO:0061623] GO:0004335; GO:0005524; GO:0005534; GO:0005737; GO:0005829; GO:0006012; GO:0016020; GO:0019388; GO:0019402; GO:0033499; GO:0061623; GO:0070062 17892 FUN_037976 410 542 266 354 269 NA NA NA NA NA NA NA 17893 FUN_008332 48 32 0 0 53 NA NA NA NA NA NA NA 17894 FUN_037974 12301 5084 5949 13663 11536 NA NA NA NA NA NA NA 17895 FUN_037975 2164 1221 1552 3801 2047 NA NA NA NA NA NA NA 17896 FUN_037970 1364 631 533 610 650 ptg000027l:982363-983836 O06997 3.18e-24 Uncharacterized FAD-linked oxidoreductase YvdP (EC 1.21.-.-) (Spore coat protein YvdP) Bacillus subtilis (strain 168) sporulation resulting in formation of a cellular spore [GO:0030435] GO:0016491; GO:0030435; GO:0071949 17897 FUN_037971 2137 1268 1130 1667 1813 ptg000027l:987004-998278 Q6ZPJ3 7.85e-31 (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O) Mus musculus (Mouse) negative regulation of apoptotic process [GO:0043066]; positive regulation of BMP signaling pathway [GO:0030513]; protein K63-linked ubiquitination [GO:0070534]; protein monoubiquitination [GO:0006513]; retrograde transport, endosome to Golgi [GO:0042147] GO:0004842; GO:0004869; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006513; GO:0016604; GO:0030513; GO:0042147; GO:0043066; GO:0061630; GO:0061631; GO:0070534 17898 FUN_008330 2135 734 784 1701 1914 NA NA NA NA NA NA NA 17899 FUN_008331 981 463 578 353 1272 ptg000002l:10460354-10471154 O15040 2.95e-50 Tectonin beta-propeller repeat-containing protein 2 (WD repeat-containing protein KIAA0329/KIAA0297) Homo sapiens (Human) autophagy [GO:0006914]; protein exit from endoplasmic reticulum [GO:0032527] GO:0005737; GO:0006914; GO:0032527 17900 FUN_017610 33 0 34 3 52 NA NA NA NA NA NA NA 17901 FUN_004989 2558 2042 1146 2191 2065 ntLink_8:29585262-29590450 Q9R1P0 5.93e-22 Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L) Mus musculus (Mouse) proteasomal protein catabolic process [GO:0010498]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0006511; GO:0010498; GO:0019773; GO:0043231 17902 FUN_004988 341 424 190 199 292 NA NA NA NA NA NA NA 17903 FUN_027515 2190 2287 1045 6 858 ptg000021l:6152730-6171214 Q9NBX4 3.01e-35 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 17904 FUN_027511 529 173 151 181 103 NA NA NA NA NA NA NA 17905 FUN_027513 0 0 0 21 0 NA NA NA NA NA NA NA 17906 FUN_027512 0 0 7 0 10 NA NA NA NA NA NA NA 17907 FUN_027519 40 0 9 57 0 NA NA NA NA NA NA NA 17908 FUN_037398 642 791 178 522 550 ptg000026l:9924286-9928678 P47862 1.79e-21 Aquaporin-3 (AQP-3) (31.4 kDa water channel protein) (Aquaglyceroporin-3) Rattus norvegicus (Rat) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 17909 FUN_037399 1391 1417 451 1084 1167 NA NA NA NA NA NA NA 17910 FUN_037392 21 0 0 0 60 NA NA NA NA NA NA NA 17911 FUN_037390 0 0 0 38 38 ptg000026l:9867314-9869852 Q99715 1.6e-22 Collagen alpha-1(XII) chain Homo sapiens (Human) cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; endodermal cell differentiation [GO:0035987] GO:0005576; GO:0005595; GO:0005615; GO:0005788; GO:0007155; GO:0030020; GO:0030199; GO:0035987; GO:0062023; GO:0070062; GO:1903561 17912 FUN_037391 0 12 14 15 0 NA NA NA NA NA NA NA 17913 FUN_037396 27 4 16 4 59 NA NA NA NA NA NA NA 17914 FUN_037397 1804 2182 805 3175 3848 ptg000026l:9911204-9922684 Q8R2N1 1.22e-21 Aquaporin-3 (AQP-3) (Aquaglyceroporin-3) Mus musculus (Mouse) cellular response to hypoxia [GO:0071456]; cellular response to oxygen-glucose deprivation [GO:0090650]; establishment of localization in cell [GO:0051649]; glycerol transmembrane transport [GO:0015793]; odontogenesis [GO:0042476]; polyol transmembrane transport [GO:0015791]; positive regulation of immune system process [GO:0002684]; renal water absorption [GO:0070295]; response to retinoic acid [GO:0032526]; urea transport [GO:0015840]; water transport [GO:0006833] GO:0002684; GO:0005654; GO:0005737; GO:0005886; GO:0005911; GO:0006833; GO:0015166; GO:0015204; GO:0015250; GO:0015254; GO:0015791; GO:0015793; GO:0015840; GO:0016323; GO:0032526; GO:0042476; GO:0042802; GO:0051649; GO:0070295; GO:0071456; GO:0090650 17915 FUN_037394 151 21 134 56 95 NA NA NA NA NA NA NA 17916 FUN_037395 54 177 126 87 107 NA NA NA NA NA NA NA 17917 FUN_004984 478 169 254 608 403 NA NA NA NA NA NA NA 17918 FUN_006095 0 13 0 0 10 NA NA NA NA NA NA NA 17919 FUN_006097 0 0 0 0 11 NA NA NA NA NA NA NA 17920 FUN_006091 0 0 18 0 3 NA NA NA NA NA NA NA 17921 FUN_005219 146 35 114 155 90 NA NA NA NA NA NA NA 17922 FUN_005216 145 61 7 32 25 ntLink_8:32877704-32878706 O42574 1.01e-38 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 17923 FUN_005217 3 0 2 1 19 NA NA NA NA NA NA NA 17924 FUN_005214 286 190 58 179 279 NA NA NA NA NA NA NA 17925 FUN_005215 991 743 445 542 264 ntLink_8:32864583-32866014 Q868M7 6.2e-156 Galactose/N-acetylgalactosamine-binding lectin CEL-III (Gal/GalNAc-binding lectin CEL-III) (CEL-III) (Hemolytic lectin CEL-III) (Lectin CEL-III) Cucumaria echinata (Sea cucumber) antibacterial humoral response [GO:0019731]; cell killing [GO:0001906]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption of membrane integrity in another organism [GO:0051673]; hemolysis in another organism [GO:0044179]; positive regulation of erythrocyte aggregation [GO:0034120]; protein homooligomerization [GO:0051260] GO:0000287; GO:0001906; GO:0005509; GO:0005534; GO:0005615; GO:0019731; GO:0030395; GO:0034120; GO:0042806; GO:0043621; GO:0044179; GO:0046871; GO:0050829; GO:0050830; GO:0051260; GO:0051673; GO:1903777 17926 FUN_005213 162 167 89 179 376 NA NA NA NA NA NA NA 17927 FUN_005210 18 0 0 0 0 NA NA NA NA NA NA NA 17928 FUN_005211 10 0 0 11 0 NA NA NA NA NA NA NA 17929 FUN_037028 20 0 4 15 28 NA NA NA NA NA NA NA 17930 FUN_037029 177 55 19 97 95 NA NA NA NA NA NA NA 17931 FUN_037024 25 0 0 7 0 NA NA NA NA NA NA NA 17932 FUN_037026 66 110 17 80 78 ptg000026l:4721547-4722983 A0JM23 1.58e-40 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 17933 FUN_037026 66 110 17 80 78 ptg000026l:4721547-4722983 A0JM23 9.01e-30 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 17934 FUN_037026 66 110 17 80 78 ptg000026l:4721547-4722983 A0JM23 4.04e-28 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 17935 FUN_037026 66 110 17 80 78 ptg000026l:4721547-4722983 A0JM23 2.56e-27 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 17936 FUN_037027 290 262 228 701 684 ptg000026l:4723304-4728102 P0CI65 7.97e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17937 FUN_037027 290 262 228 701 684 ptg000026l:4723304-4728102 P0CI65 2.6e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17938 FUN_037027 290 262 228 701 684 ptg000026l:4723304-4728102 P0CI65 1.35e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17939 FUN_037027 290 262 228 701 684 ptg000026l:4723304-4728102 P0CI65 7.71e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17940 FUN_037027 290 262 228 701 684 ptg000026l:4723304-4728102 P0CI65 1.62e-40 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17941 FUN_004486 27 29 43 10 40 NA NA NA NA NA NA NA 17942 FUN_037022 54 37 7 76 0 NA NA NA NA NA NA NA 17943 FUN_037023 340 149 209 179 207 ptg000026l:4668211-4672108 P0CI65 5.14e-51 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17944 FUN_037023 340 149 209 179 207 ptg000026l:4668211-4672108 P0CI65 2.25e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17945 FUN_037023 340 149 209 179 207 ptg000026l:4668211-4672108 P0CI65 6.41e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 17946 FUN_004487 294 218 214 399 332 NA NA NA NA NA NA NA 17947 FUN_006548 121 181 34 55 321 NA NA NA NA NA NA NA 17948 FUN_006547 7 0 0 273 0 NA NA NA NA NA NA NA 17949 FUN_006546 23 0 0 15 22 NA NA NA NA NA NA NA 17950 FUN_006545 0 0 0 16 0 NA NA NA NA NA NA NA 17951 FUN_006544 211 0 127 304 88 NA NA NA NA NA NA NA 17952 FUN_006543 144 0 22 180 4 NA NA NA NA NA NA NA 17953 FUN_006542 3 129 31 48 178 NA NA NA NA NA NA NA 17954 FUN_006541 6 55 10 5 140 NA NA NA NA NA NA NA 17955 FUN_032614 67 82 33 29 28 NA NA NA NA NA NA NA 17956 FUN_032615 331 379 53 176 53 NA NA NA NA NA NA NA 17957 FUN_032616 145 197 157 223 120 NA NA NA NA NA NA NA 17958 FUN_032610 1588 952 860 1432 1514 NA NA NA NA NA NA NA 17959 FUN_032611 1384 514 595 1417 1043 ptg000023l:33892570-33902988 P22003 8.53e-32 Bone morphogenetic protein 5 (BMP-5) Homo sapiens (Human) allantois development [GO:1905069]; anterior head development [GO:0097065]; BMP signaling pathway [GO:0030509]; cardiac muscle tissue development [GO:0048738]; cardiac septum morphogenesis [GO:0060411]; cartilage development [GO:0051216]; chorio-allantoic fusion [GO:0060710]; ear development [GO:0043583]; endocardial cushion formation [GO:0003272]; heart trabecula morphogenesis [GO:0061384]; hindbrain development [GO:0030902]; male genitalia development [GO:0030539]; negative regulation of aldosterone biosynthetic process [GO:0032348]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cortisol biosynthetic process [GO:2000065]; negative regulation of epithelial to mesenchymal transition [GO:0010719]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of insulin-like growth factor receptor signaling pathway [GO:0043569]; negative regulation of mononuclear cell migration [GO:0071676]; negative regulation of steroid biosynthetic process [GO:0010894]; neural fold elevation formation [GO:0021502]; ossification [GO:0001503]; pattern specification process [GO:0007389]; pericardium morphogenesis [GO:0003344]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of dendrite development [GO:1900006]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; skeletal system development [GO:0001501]; SMAD protein signal transduction [GO:0060395]; type B pancreatic cell development [GO:0003323] GO:0001501; GO:0001503; GO:0003272; GO:0003323; GO:0003344; GO:0005125; GO:0005615; GO:0007389; GO:0008083; GO:0008284; GO:0008285; GO:0010719; GO:0010862; GO:0010894; GO:0021502; GO:0030509; GO:0030539; GO:0030902; GO:0031982; GO:0032348; GO:0043569; GO:0043583; GO:0045944; GO:0048738; GO:0050679; GO:0051216; GO:0060037; GO:0060395; GO:0060411; GO:0060710; GO:0061384; GO:0070700; GO:0071676; GO:0097065; GO:1900006; GO:1902042; GO:1905069; GO:2000065 17960 FUN_032612 86 185 196 107 56 NA NA NA NA NA NA NA 17961 FUN_032613 190 640 435 174 337 NA NA NA NA NA NA NA 17962 FUN_032618 0 12 60 0 23 NA NA NA NA NA NA NA 17963 FUN_032619 0 0 0 0 11 NA NA NA NA NA NA NA 17964 FUN_003686 45 43 0 10 25 ntLink_8:14430904-14433283 O70165 1.92e-40 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 17965 FUN_003684 209 44 0 4 5 NA NA NA NA NA NA NA 17966 FUN_003682 0 0 0 34 0 NA NA NA NA NA NA NA 17967 FUN_003681 0 0 0 8 0 NA NA NA NA NA NA NA 17968 FUN_003680 0 0 0 10 0 NA NA NA NA NA NA NA 17969 FUN_003689 265 356 49 90 144 ntLink_8:14452051-14483402 P19477 2.94e-40 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 17970 FUN_003689 265 356 49 90 144 ntLink_8:14452051-14483402 P19477 3.59e-39 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 17971 FUN_034618 0 0 0 7 10 NA NA NA NA NA NA NA 17972 FUN_034616 0 0 9 0 0 ptg000024l:9746912-9752349 Q09575 2.15e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 17973 FUN_034617 0 0 17 0 67 NA NA NA NA NA NA NA 17974 FUN_034614 7 0 0 0 4 NA NA NA NA NA NA NA 17975 FUN_034615 0 0 0 0 10 NA NA NA NA NA NA NA 17976 FUN_034612 0 14 0 13 0 NA NA NA NA NA NA NA 17977 FUN_041908 2511 1991 1466 2130 1755 NA NA NA NA NA NA NA 17978 FUN_041909 6 0 5 2 1 NA NA NA NA NA NA NA 17979 FUN_041906 266 360 197 221 218 ptg000035l:8778789-8780919 Q8TEB9 6.46e-61 Rhomboid-related protein 4 (RRP4) (EC 3.4.21.105) (Rhomboid domain-containing protein 1) (Rhomboid-like protein 4) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to unfolded protein [GO:0034620]; cellular response to UV [GO:0034644]; ERAD pathway [GO:0036503]; membrane protein intracellular domain proteolysis [GO:0031293]; membrane protein proteolysis [GO:0033619]; membrane protein proteolysis involved in retrograde protein transport, ER to cytosol [GO:1904211]; negative regulation of apoptotic process [GO:0043066]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein processing [GO:0010954]; positive regulation of secretion [GO:0051047]; post-translational protein modification [GO:0043687]; spermatid differentiation [GO:0048515] GO:0004175; GO:0004252; GO:0005783; GO:0005789; GO:0006915; GO:0010954; GO:0031293; GO:0031966; GO:0033619; GO:0034620; GO:0034644; GO:0036503; GO:0043066; GO:0043687; GO:0044322; GO:0045732; GO:0048515; GO:0051047; GO:1904211 17980 FUN_041907 2123 1344 1300 1973 2015 NA NA NA NA NA NA NA 17981 FUN_041904 1998 1082 1348 2585 2242 NA NA NA NA NA NA NA 17982 FUN_041905 256 255 214 272 413 NA NA NA NA NA NA NA 17983 FUN_041902 727 686 419 638 522 NA NA NA NA NA NA NA 17984 FUN_041903 123 0 20 106 158 ptg000035l:8748652-8751476 A2ADU9 4.56e-26 Acyl-CoA wax alcohol acyltransferase 1 (EC 2.3.1.75) (Diacylglycerol O-acyltransferase 2-like protein 3) (Long-chain-alcohol O-fatty-acyltransferase 1) Mus musculus (Mouse) cellular lipid metabolic process [GO:0044255]; lipid metabolic process [GO:0006629] GO:0005789; GO:0006629; GO:0008374; GO:0044255; GO:0047196; GO:0102966 17985 FUN_041900 472 594 414 733 403 NA NA NA NA NA NA NA 17986 FUN_041901 4362 4088 2458 2902 1513 NA NA NA NA NA NA NA 17987 FUN_008483 0 8 18 41 0 NA NA NA NA NA NA NA 17988 FUN_001018 134 106 45 62 112 NA NA NA NA NA NA NA 17989 FUN_001019 4586 3540 3183 3888 4461 NA NA NA NA NA NA NA 17990 FUN_001014 1714 1885 1844 1852 961 NA NA NA NA NA NA NA 17991 FUN_001015 2 3 73 73 90 NA NA NA NA NA NA NA 17992 FUN_001016 2953 1160 883 1952 1167 NA NA NA NA NA NA NA 17993 FUN_001017 299 182 116 65 140 NA NA NA NA NA NA NA 17994 FUN_001010 320 181 191 223 221 NA NA NA NA NA NA NA 17995 FUN_001011 1479 1208 1000 2214 2196 NA NA NA NA NA NA NA 17996 FUN_001012 2291 942 992 1615 1799 NA NA NA NA NA NA NA 17997 FUN_001013 1712 1833 1160 1335 1851 ntLink_6:7218562-7219252 Q5R6Z8 4.25e-49 Calcyclin-binding protein (CacyBP) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005634; GO:0005737; GO:0015631; GO:0031625; GO:0044548 17998 FUN_029238 125 285 86 291 243 NA NA NA NA NA NA NA 17999 FUN_029239 1276 821 469 851 706 NA NA NA NA NA NA NA 18000 FUN_029236 1206 2571 284 578 530 NA NA NA NA NA NA NA 18001 FUN_029232 89 28 34 91 58 NA NA NA NA NA NA NA 18002 FUN_012421 846 382 313 543 248 NA NA NA NA NA NA NA 18003 FUN_012420 8743 15418 7264 9721 5674 NA NA NA NA NA NA NA 18004 FUN_029582 188 43 55 53 24 ptg000023l:3498221-3501463 F6QEU4 1.16e-52 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 18005 FUN_012422 2503 1143 881 1993 1360 NA NA NA NA NA NA NA 18006 FUN_012425 0 74 0 26 0 NA NA NA NA NA NA NA 18007 FUN_029585 0 0 0 0 9 NA NA NA NA NA NA NA 18008 FUN_012427 791 2001 217 1708 826 NA NA NA NA NA NA NA 18009 FUN_029587 23 16 37 3 20 NA NA NA NA NA NA NA 18010 FUN_029588 4156 1838 1209 1307 1376 NA NA NA NA NA NA NA 18011 FUN_016551 23 62 50 33 202 ptg000011l:4622166-4625884 Q96AY4 1.58e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18012 FUN_016551 23 62 50 33 202 ptg000011l:4622166-4625884 Q96AY4 5.37e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18013 FUN_016551 23 62 50 33 202 ptg000011l:4622166-4625884 Q96AY4 1.47e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18014 FUN_016551 23 62 50 33 202 ptg000011l:4622166-4625884 Q96AY4 2.36e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18015 FUN_016551 23 62 50 33 202 ptg000011l:4622166-4625884 Q96AY4 1.37e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18016 FUN_016551 23 62 50 33 202 ptg000011l:4622166-4625884 Q96AY4 2.8e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18017 FUN_016555 71 118 14 106 57 ptg000011l:4683570-4688728 Q96AY4 9.77e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18018 FUN_016555 71 118 14 106 57 ptg000011l:4683570-4688728 Q96AY4 8.8e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18019 FUN_016555 71 118 14 106 57 ptg000011l:4683570-4688728 Q96AY4 8.34e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18020 FUN_016555 71 118 14 106 57 ptg000011l:4683570-4688728 Q96AY4 1.19e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18021 FUN_016555 71 118 14 106 57 ptg000011l:4683570-4688728 Q96AY4 2.6e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18022 FUN_016555 71 118 14 106 57 ptg000011l:4683570-4688728 Q96AY4 9.69e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18023 FUN_016554 0 3 1 7 8 NA NA NA NA NA NA NA 18024 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 7.27e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18025 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 4.63e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18026 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 1.87e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18027 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 4.4e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18028 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 4.12e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18029 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 7.02e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18030 FUN_016557 97 86 108 144 119 ptg000011l:4708536-4717271 Q96AY4 4.4e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18031 FUN_040351 26 15 34 4 20 NA NA NA NA NA NA NA 18032 FUN_016559 41 48 23 54 47 ptg000011l:4728072-4737501 Q96AY4 2.44e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18033 FUN_016559 41 48 23 54 47 ptg000011l:4728072-4737501 Q96AY4 2.25e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18034 FUN_016559 41 48 23 54 47 ptg000011l:4728072-4737501 Q96AY4 8.16e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18035 FUN_016559 41 48 23 54 47 ptg000011l:4728072-4737501 Q96AY4 4.4e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18036 FUN_016559 41 48 23 54 47 ptg000011l:4728072-4737501 Q96AY4 2.6e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18037 FUN_016559 41 48 23 54 47 ptg000011l:4728072-4737501 Q96AY4 2.53e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18038 FUN_042257 20 0 2 0 0 NA NA NA NA NA NA NA 18039 FUN_004155 44 0 23 16 0 NA NA NA NA NA NA NA 18040 FUN_004153 229 319 129 168 67 NA NA NA NA NA NA NA 18041 FUN_043676 0 0 17 11 14 NA NA NA NA NA NA NA 18042 FUN_043677 43 0 26 0 37 NA NA NA NA NA NA NA 18043 FUN_043674 469 7 965 4 218 NA NA NA NA NA NA NA 18044 FUN_043675 26 0 5 0 19 NA NA NA NA NA NA NA 18045 FUN_043670 0 0 63 163 0 NA NA NA NA NA NA NA 18046 FUN_043671 52 35 52 39 69 NA NA NA NA NA NA NA 18047 FUN_004151 741 2035 205 84 188 NA NA NA NA NA NA NA 18048 FUN_010478 2 0 2 6 4 NA NA NA NA NA NA NA 18049 FUN_016089 829 409 229 456 438 NA NA NA NA NA NA NA 18050 FUN_016088 4899 2023 1207 2005 908 ptg000010l:1465680-1467924 A6NFN9 1.18e-63 Protein ANKUB1 (Ankyrin repeat and ubiquitin domain-containing 1) Homo sapiens (Human) NA NA 18051 FUN_016083 12054 10999 8327 11828 9064 ptg000010l:1399361-1406367 O77404 1.22e-21 Tryparedoxin (TryX) Trypanosoma brucei brucei NA GO:0004791 18052 FUN_016082 2543 2003 1407 1838 1471 NA NA NA NA NA NA NA 18053 FUN_016081 294 169 196 119 139 ptg000010l:1372536-1374838 Q9NW07 7.47e-37 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 18054 FUN_016081 294 169 196 119 139 ptg000010l:1372536-1374838 Q9NW07 3.91e-35 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 18055 FUN_016081 294 169 196 119 139 ptg000010l:1372536-1374838 Q9NW07 5.92e-33 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 18056 FUN_016081 294 169 196 119 139 ptg000010l:1372536-1374838 Q9NW07 8.77e-25 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 18057 FUN_016081 294 169 196 119 139 ptg000010l:1372536-1374838 Q9NW07 9.01e-25 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 18058 FUN_016081 294 169 196 119 139 ptg000010l:1372536-1374838 Q9NW07 4.17e-22 Zinc finger protein 358 Homo sapiens (Human) embryonic forelimb morphogenesis [GO:0035115]; neural tube development [GO:0021915]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000978; GO:0003700; GO:0005634; GO:0006357; GO:0019827; GO:0021915; GO:0035115; GO:0046872 18059 FUN_016080 122064 110270 68111 135753 93477 ptg000010l:1355266-1362272 B8VIX3 1.38e-171 Uncharacterized skeletal organic matrix protein 6 (Uncharacterized SOMP-6) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18060 FUN_016087 61 63 21 64 80 NA NA NA NA NA NA NA 18061 FUN_016085 2090 1152 966 1772 1298 NA NA NA NA NA NA NA 18062 FUN_016084 54 23 34 50 85 NA NA NA NA NA NA NA 18063 FUN_028188 541 625 748 1262 976 NA NA NA NA NA NA NA 18064 FUN_028187 126 93 84 125 101 NA NA NA NA NA NA NA 18065 FUN_028186 3350 3075 1872 3691 2995 NA NA NA NA NA NA NA 18066 FUN_028183 0 10 0 0 0 ptg000021l:16604225-16606583 A0JPI9 3.05e-37 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 18067 FUN_028181 4861 3408 2751 4516 4531 ptg000021l:16587759-16601069 O88761 1.67e-41 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] GO:0000502; GO:0005634; GO:0008540; GO:0022624; GO:0030234; GO:0031625; GO:0034515; GO:0042176; GO:0043161 18068 FUN_028181 4861 3408 2751 4516 4531 ptg000021l:16587759-16601069 O88761 9.44e-38 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] GO:0000502; GO:0005634; GO:0008540; GO:0022624; GO:0030234; GO:0031625; GO:0034515; GO:0042176; GO:0043161 18069 FUN_028181 4861 3408 2751 4516 4531 ptg000021l:16587759-16601069 O88761 9.44e-38 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] GO:0000502; GO:0005634; GO:0008540; GO:0022624; GO:0030234; GO:0031625; GO:0034515; GO:0042176; GO:0043161 18070 FUN_028181 4861 3408 2751 4516 4531 ptg000021l:16587759-16601069 O88761 9.44e-38 26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112) Rattus norvegicus (Rat) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of protein catabolic process [GO:0042176] GO:0000502; GO:0005634; GO:0008540; GO:0022624; GO:0030234; GO:0031625; GO:0034515; GO:0042176; GO:0043161 18071 FUN_028180 1595 859 1053 1991 1822 ptg000021l:16533082-16587466 O73853 2.6e-120 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 18072 FUN_026185 92 93 148 133 154 NA NA NA NA NA NA NA 18073 FUN_018027 943 1313 1234 1922 1281 ptg000012l:3548832-3551527 A5D7P8 9.29e-21 SOSS complex subunit B2 (Nucleic acid-binding protein 1) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2A) (Sensor of single-strand DNA complex subunit B2) (Sensor of ssDNA subunit B2) (SOSS-B2) (Single-stranded DNA-binding protein 2) Bos taurus (Bovine) double-strand break repair via homologous recombination [GO:0000724]; response to ionizing radiation [GO:0010212] GO:0000724; GO:0003677; GO:0010212; GO:0031090; GO:0070876 18074 FUN_023665 0 0 0 0 16 NA NA NA NA NA NA NA 18075 FUN_018025 180 35 69 47 15 NA NA NA NA NA NA NA 18076 FUN_023669 3637 1417 1756 3177 2107 NA NA NA NA NA NA NA 18077 FUN_010869 0 10 0 0 0 NA NA NA NA NA NA NA 18078 FUN_027807 0 0 0 0 6 NA NA NA NA NA NA NA 18079 FUN_010861 0 11 9 0 0 NA NA NA NA NA NA NA 18080 FUN_010860 0 12 13 0 6 NA NA NA NA NA NA NA 18081 FUN_010867 0 23 0 0 0 NA NA NA NA NA NA NA 18082 FUN_010866 16 14 0 2 2 NA NA NA NA NA NA NA 18083 FUN_010865 31 0 0 29 0 NA NA NA NA NA NA NA 18084 FUN_018022 2466 1329 1969 1788 1895 ptg000012l:3468913-3483043 P10394 2.64e-71 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18085 FUN_018022 2466 1329 1969 1788 1895 ptg000012l:3468913-3483043 P10394 1.61e-21 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18086 FUN_018021 3160 2750 1809 2355 1449 NA NA NA NA NA NA NA 18087 FUN_018020 757 564 609 787 527 NA NA NA NA NA NA NA 18088 FUN_041129 35 71 458 37 10 NA NA NA NA NA NA NA 18089 FUN_041125 25 8 12 0 121 NA NA NA NA NA NA NA 18090 FUN_009021 409 407 449 606 397 NA NA NA NA NA NA NA 18091 FUN_009020 396 221 315 434 382 NA NA NA NA NA NA NA 18092 FUN_009023 16054 20040 8284 23165 16804 ptg000004l:1538736-1543402 Q92519 3.37e-63 Tribbles homolog 2 (TRB-2) Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of MAP kinase activity [GO:0043405] GO:0004860; GO:0005634; GO:0005737; GO:0005856; GO:0006469; GO:0031434; GO:0031625; GO:0032436; GO:0032693; GO:0043405; GO:0045599; GO:0055106; GO:0061629 18093 FUN_009023 16054 20040 8284 23165 16804 ptg000004l:1538736-1543402 Q92519 1.97e-40 Tribbles homolog 2 (TRB-2) Homo sapiens (Human) negative regulation of fat cell differentiation [GO:0045599]; negative regulation of interleukin-10 production [GO:0032693]; negative regulation of protein kinase activity [GO:0006469]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of MAP kinase activity [GO:0043405] GO:0004860; GO:0005634; GO:0005737; GO:0005856; GO:0006469; GO:0031434; GO:0031625; GO:0032436; GO:0032693; GO:0043405; GO:0045599; GO:0055106; GO:0061629 18094 FUN_009022 1991 1257 980 1883 1581 NA NA NA NA NA NA NA 18095 FUN_009025 29 14 5 23 21 NA NA NA NA NA NA NA 18096 FUN_009024 105 173 91 260 317 NA NA NA NA NA NA NA 18097 FUN_009027 22 0 0 41 41 NA NA NA NA NA NA NA 18098 FUN_009026 373 178 65 370 443 NA NA NA NA NA NA NA 18099 FUN_009028 5 0 11 5 21 NA NA NA NA NA NA NA 18100 FUN_022134 74 40 42 55 20 ptg000016l:5652491-5653442 B8UU78 1.76e-100 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18101 FUN_022135 86 43 42 142 13 ptg000016l:5656270-5663922 B8UU78 2.22e-108 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18102 FUN_022135 86 43 42 142 13 ptg000016l:5656270-5663922 B8UU78 1.7e-26 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18103 FUN_022136 29 26 49 136 72 ptg000016l:5677721-5692819 B8UU78 0 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18104 FUN_022136 29 26 49 136 72 ptg000016l:5677721-5692819 B8UU78 4.03e-103 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18105 FUN_022136 29 26 49 136 72 ptg000016l:5677721-5692819 B8UU78 1.35e-78 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18106 FUN_022136 29 26 49 136 72 ptg000016l:5677721-5692819 B8UU78 1.25e-27 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18107 FUN_022136 29 26 49 136 72 ptg000016l:5677721-5692819 B8UU78 3.99e-26 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 18108 FUN_022131 10 0 0 1 6 NA NA NA NA NA NA NA 18109 FUN_022138 36 6 17 2 278 NA NA NA NA NA NA NA 18110 FUN_040658 11 0 15 0 33 NA NA NA NA NA NA NA 18111 FUN_010130 12 3 1 9 14 NA NA NA NA NA NA NA 18112 FUN_040657 0 0 0 15 0 NA NA NA NA NA NA NA 18113 FUN_023365 144 188 115 96 144 ptg000017l:6714688-6715305 Q91WQ5 1.44e-22 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta) Mus musculus (Mouse) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000123; GO:0000124; GO:0003713; GO:0005634; GO:0006282; GO:0006355; GO:0006357; GO:0016573; GO:0016607; GO:0033276; GO:0035521; GO:0035522; GO:0036464; GO:0043484; GO:0043966; GO:0045893; GO:1904672 18114 FUN_032562 6 0 0 0 0 NA NA NA NA NA NA NA 18115 FUN_008048 3111 1713 1231 2022 1401 NA NA NA NA NA NA NA 18116 FUN_008049 3361 2224 1543 1000 968 NA NA NA NA NA NA NA 18117 FUN_024479 1 21 2 6 2 NA NA NA NA NA NA NA 18118 FUN_024478 8 17 14 58 73 NA NA NA NA NA NA NA 18119 FUN_014339 0 25 68 6 15 NA NA NA NA NA NA NA 18120 FUN_024473 1237 805 640 1089 664 NA NA NA NA NA NA NA 18121 FUN_024472 1066 421 253 571 690 NA NA NA NA NA NA NA 18122 FUN_024471 365 175 121 443 431 NA NA NA NA NA NA NA 18123 FUN_024470 216 155 85 510 15 NA NA NA NA NA NA NA 18124 FUN_008044 159 65 114 33 147 NA NA NA NA NA NA NA 18125 FUN_024476 1087 701 537 690 787 ptg000018l:6809296-6823677 A5D8S5 8.16e-25 E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of apoptotic process [GO:0043066]; neuron migration [GO:0001764]; positive regulation of JNK cascade [GO:0046330]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043370]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564] GO:0001764; GO:0005078; GO:0005794; GO:0016567; GO:0030027; GO:0032436; GO:0043066; GO:0043370; GO:0046330; GO:0046872; GO:0048471; GO:0051865; GO:0061630; GO:2000564 18126 FUN_008046 347 338 282 297 126 NA NA NA NA NA NA NA 18127 FUN_024474 867 1013 325 571 471 ptg000018l:6793742-6796977 A5D8S5 2.65e-23 E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of apoptotic process [GO:0043066]; neuron migration [GO:0001764]; positive regulation of JNK cascade [GO:0046330]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; regulation of CD4-positive, alpha-beta T cell differentiation [GO:0043370]; regulation of CD8-positive, alpha-beta T cell proliferation [GO:2000564] GO:0001764; GO:0005078; GO:0005794; GO:0016567; GO:0030027; GO:0032436; GO:0043066; GO:0043370; GO:0046330; GO:0046872; GO:0048471; GO:0051865; GO:0061630; GO:2000564 18128 FUN_014935 52 29 37 40 16 NA NA NA NA NA NA NA 18129 FUN_014931 37 43 0 75 24 NA NA NA NA NA NA NA 18130 FUN_014933 18 0 25 67 31 NA NA NA NA NA NA NA 18131 FUN_014932 3055 1768 1670 2918 1573 NA NA NA NA NA NA NA 18132 FUN_038753 1456 953 829 1527 2411 ptg000027l:10909073-10934786 P42620 6.5e-53 Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) Escherichia coli (strain K12) NA GO:0004364; GO:0005737; GO:0016672 18133 FUN_038753 1456 953 829 1527 2411 ptg000027l:10909073-10934786 P42620 3.44e-51 Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) Escherichia coli (strain K12) NA GO:0004364; GO:0005737; GO:0016672 18134 FUN_038753 1456 953 829 1527 2411 ptg000027l:10909073-10934786 P42620 3.71e-50 Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) Escherichia coli (strain K12) NA GO:0004364; GO:0005737; GO:0016672 18135 FUN_038752 756 797 343 580 1604 ptg000027l:10898352-10904007 P42620 2.02e-52 Glutathionyl-hydroquinone reductase YqjG (GS-HQR) (EC 1.8.5.7) Escherichia coli (strain K12) NA GO:0004364; GO:0005737; GO:0016672 18136 FUN_038751 16 17 0 70 20 NA NA NA NA NA NA NA 18137 FUN_038750 18 132 104 51 17 NA NA NA NA NA NA NA 18138 FUN_038757 337 299 254 359 238 ptg000027l:10973632-11003812 Q8I7P9 2.63e-57 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 18139 FUN_038757 337 299 254 359 238 ptg000027l:10973632-11003812 Q8I7P9 2.63e-57 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 18140 FUN_038756 1789 2378 1066 1513 697 ptg000027l:10962744-10964072 Q8NBN7 1.55e-35 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 18141 FUN_038755 1197 609 441 553 540 ptg000027l:10948215-10962667 Q29L80 1.03e-70 PITH domain-containing protein GA19395 Drosophila pseudoobscura pseudoobscura (Fruit fly) NA NA 18142 FUN_038754 12 0 155 229 263 NA NA NA NA NA NA NA 18143 FUN_028969 531 532 418 403 466 NA NA NA NA NA NA NA 18144 FUN_028968 4360 3359 826 2206 2166 ptg000022l:6538694-6539111 O97725 9.65e-31 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (Complex I-B17.2) (CI-B17.2) (CIB17.2) (NADH-ubiquinone oxidoreductase subunit B17.2) Bos taurus (Bovine) mitochondrial respiratory chain complex I assembly [GO:0032981]; response to oxidative stress [GO:0006979] GO:0005747; GO:0006979; GO:0032981 18145 FUN_015049 0 0 0 10 21 NA NA NA NA NA NA NA 18146 FUN_015046 1395 1474 782 1084 783 ptg000009l:5608809-5614383 Q6DFM1 4.74e-49 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin remodeling [GO:0006338] GO:0000228; GO:0003677; GO:0006338; GO:0070603 18147 FUN_015046 1395 1474 782 1084 783 ptg000009l:5608809-5614383 Q6DFM1 1.13e-46 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) chromatin remodeling [GO:0006338] GO:0000228; GO:0003677; GO:0006338; GO:0070603 18148 FUN_028960 2631 4598 2046 2654 2536 NA NA NA NA NA NA NA 18149 FUN_028963 592 474 209 729 223 NA NA NA NA NA NA NA 18150 FUN_028962 452 348 154 758 638 NA NA NA NA NA NA NA 18151 FUN_028965 1359 592 207 1012 727 NA NA NA NA NA NA NA 18152 FUN_028964 91 13 4 7 14 NA NA NA NA NA NA NA 18153 FUN_028967 381 406 179 276 157 NA NA NA NA NA NA NA 18154 FUN_028966 855 891 466 486 788 NA NA NA NA NA NA NA 18155 FUN_014271 0 0 1 8 0 NA NA NA NA NA NA NA 18156 FUN_034282 2694 5639 2660 3983 2568 NA NA NA NA NA NA NA 18157 FUN_020597 0 0 0 0 1282 NA NA NA NA NA NA NA 18158 FUN_039088 2504 1546 1580 2461 2629 NA NA NA NA NA NA NA 18159 FUN_039089 37 30 11 88 69 NA NA NA NA NA NA NA 18160 FUN_039080 71 0 10 0 7 NA NA NA NA NA NA NA 18161 FUN_039081 37 21 0 0 24 NA NA NA NA NA NA NA 18162 FUN_039082 4326 3482 2403 4043 3516 ptg000027l:14348448-14385116 F1SS88 1.27e-24 Cilia- and flagella-associated protein 52 (WD repeat-containing protein 16) Sus scrofa (Pig) cilium assembly [GO:0060271]; establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] GO:0005879; GO:0005930; GO:0030317; GO:0060271; GO:0061966; GO:0097729 18163 FUN_039083 0 16 3 185 0 NA NA NA NA NA NA NA 18164 FUN_039084 9 36 19 12 29 NA NA NA NA NA NA NA 18165 FUN_039085 4249 5851 2129 2655 2040 NA NA NA NA NA NA NA 18166 FUN_039086 1873 1732 1144 2045 1305 NA NA NA NA NA NA NA 18167 FUN_020882 104 21 84 78 110 NA NA NA NA NA NA NA 18168 FUN_020883 2 0 0 0 59 NA NA NA NA NA NA NA 18169 FUN_022956 1 0 27 1 40 NA NA NA NA NA NA NA 18170 FUN_041322 0 0 6 17 14 NA NA NA NA NA NA NA 18171 FUN_022954 63 24 27 34 0 NA NA NA NA NA NA NA 18172 FUN_022955 2105 1486 1151 1983 2326 NA NA NA NA NA NA NA 18173 FUN_022952 17 0 0 0 0 NA NA NA NA NA NA NA 18174 FUN_022953 2 2 4 2 26 NA NA NA NA NA NA NA 18175 FUN_022950 12 0 18 0 24 NA NA NA NA NA NA NA 18176 FUN_027353 7 0 14 0 64 NA NA NA NA NA NA NA 18177 FUN_027351 0 0 16 0 19 NA NA NA NA NA NA NA 18178 FUN_027356 33 7 15 15 19 NA NA NA NA NA NA NA 18179 FUN_022958 937 1021 2676 1035 666 NA NA NA NA NA NA NA 18180 FUN_027354 10 0 17 0 34 NA NA NA NA NA NA NA 18181 FUN_040792 0 14 0 0 0 NA NA NA NA NA NA NA 18182 FUN_004017 1800 506 1147 2093 1450 ntLink_8:18129545-18161990 Q28943 6.78e-47 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Sus scrofa (Pig) beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; uracil catabolic process [GO:0006212] GO:0005737; GO:0006212; GO:0006214; GO:0010181; GO:0017113; GO:0019483; GO:0042803; GO:0046872; GO:0050660; GO:0050661; GO:0051539 18183 FUN_004017 1800 506 1147 2093 1450 ntLink_8:18129545-18161990 Q28943 2.56e-29 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Sus scrofa (Pig) beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; uracil catabolic process [GO:0006212] GO:0005737; GO:0006212; GO:0006214; GO:0010181; GO:0017113; GO:0019483; GO:0042803; GO:0046872; GO:0050660; GO:0050661; GO:0051539 18184 FUN_004017 1800 506 1147 2093 1450 ntLink_8:18129545-18161990 Q28943 2.06e-27 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Sus scrofa (Pig) beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; uracil catabolic process [GO:0006212] GO:0005737; GO:0006212; GO:0006214; GO:0010181; GO:0017113; GO:0019483; GO:0042803; GO:0046872; GO:0050660; GO:0050661; GO:0051539 18185 FUN_004017 1800 506 1147 2093 1450 ntLink_8:18129545-18161990 Q28943 9.08e-22 Dihydropyrimidine dehydrogenase [NADP(+)] (DHPDHase) (DPD) (EC 1.3.1.2) (Dihydrothymine dehydrogenase) (Dihydrouracil dehydrogenase) Sus scrofa (Pig) beta-alanine biosynthetic process [GO:0019483]; thymidine catabolic process [GO:0006214]; uracil catabolic process [GO:0006212] GO:0005737; GO:0006212; GO:0006214; GO:0010181; GO:0017113; GO:0019483; GO:0042803; GO:0046872; GO:0050660; GO:0050661; GO:0051539 18186 FUN_004016 318 247 154 76 173 ntLink_8:18126381-18127137 Q06AA5 6.31e-40 Tetraspanin-9 (Tspan-9) Sus scrofa (Pig) NA GO:0005886 18187 FUN_004015 496 227 246 422 289 NA NA NA NA NA NA NA 18188 FUN_004011 357 56 31 295 235 NA NA NA NA NA NA NA 18189 FUN_004010 1665 1250 954 2132 1017 ntLink_8:17999787-18020825 Q6DFV5 1.83e-52 Probable helicase with zinc finger domain (EC 3.6.4.-) Mus musculus (Mouse) RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005829; GO:0016787; GO:0035194; GO:0043186; GO:0046872 18190 FUN_004019 16 0 16 0 12 NA NA NA NA NA NA NA 18191 FUN_004018 40 18 12 46 17 NA NA NA NA NA NA NA 18192 FUN_027829 6535 3277 1528 4102 2362 NA NA NA NA NA NA NA 18193 FUN_027828 72 0 0 0 0 NA NA NA NA NA NA NA 18194 FUN_018009 45 0 68 77 42 ptg000012l:3121611-3125093 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 18195 FUN_018009 45 0 68 77 42 ptg000012l:3121611-3125093 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 18196 FUN_018009 45 0 68 77 42 ptg000012l:3121611-3125093 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 18197 FUN_018009 45 0 68 77 42 ptg000012l:3121611-3125093 Q5R5U3 0 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 18198 FUN_018009 45 0 68 77 42 ptg000012l:3121611-3125093 Q5R5U3 3.12e-170 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 18199 FUN_018009 45 0 68 77 42 ptg000012l:3121611-3125093 Q5R5U3 1.03e-165 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 18200 FUN_018008 2864 2249 1642 2847 2091 ptg000012l:3079482-3120350 P07756 6.18e-36 Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; anion homeostasis [GO:0055081]; carbamoyl phosphate biosynthetic process [GO:0070409]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucagon stimulus [GO:0071377]; cellular response to oleic acid [GO:0071400]; glutamine metabolic process [GO:0006541]; hepatocyte differentiation [GO:0070365]; homocysteine metabolic process [GO:0050667]; liver development [GO:0001889]; midgut development [GO:0007494]; nitric oxide metabolic process [GO:0046209]; nitrogen compound metabolic process [GO:0006807]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to dexamethasone [GO:0071548]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to oleic acid [GO:0034201]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; sequestering of metal ion [GO:0051238]; triglyceride catabolic process [GO:0019433]; urea cycle [GO:0000050]; vasodilation [GO:0042311] GO:0000050; GO:0001889; GO:0004087; GO:0004088; GO:0004175; GO:0005509; GO:0005524; GO:0005543; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0006207; GO:0006541; GO:0006807; GO:0007494; GO:0009410; GO:0009636; GO:0010043; GO:0014075; GO:0016595; GO:0019433; GO:0032094; GO:0032496; GO:0032991; GO:0033762; GO:0034201; GO:0036094; GO:0042311; GO:0042594; GO:0042645; GO:0043200; GO:0044344; GO:0044877; GO:0046209; GO:0046872; GO:0048545; GO:0050667; GO:0051238; GO:0051384; GO:0051591; GO:0055081; GO:0060416; GO:0070365; GO:0070409; GO:0071242; GO:0071320; GO:0071377; GO:0071400; GO:0071548; GO:0072341 18201 FUN_018008 2864 2249 1642 2847 2091 ptg000012l:3079482-3120350 P07756 6.18e-36 Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; anion homeostasis [GO:0055081]; carbamoyl phosphate biosynthetic process [GO:0070409]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucagon stimulus [GO:0071377]; cellular response to oleic acid [GO:0071400]; glutamine metabolic process [GO:0006541]; hepatocyte differentiation [GO:0070365]; homocysteine metabolic process [GO:0050667]; liver development [GO:0001889]; midgut development [GO:0007494]; nitric oxide metabolic process [GO:0046209]; nitrogen compound metabolic process [GO:0006807]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to dexamethasone [GO:0071548]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to oleic acid [GO:0034201]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; sequestering of metal ion [GO:0051238]; triglyceride catabolic process [GO:0019433]; urea cycle [GO:0000050]; vasodilation [GO:0042311] GO:0000050; GO:0001889; GO:0004087; GO:0004088; GO:0004175; GO:0005509; GO:0005524; GO:0005543; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0006207; GO:0006541; GO:0006807; GO:0007494; GO:0009410; GO:0009636; GO:0010043; GO:0014075; GO:0016595; GO:0019433; GO:0032094; GO:0032496; GO:0032991; GO:0033762; GO:0034201; GO:0036094; GO:0042311; GO:0042594; GO:0042645; GO:0043200; GO:0044344; GO:0044877; GO:0046209; GO:0046872; GO:0048545; GO:0050667; GO:0051238; GO:0051384; GO:0051591; GO:0055081; GO:0060416; GO:0070365; GO:0070409; GO:0071242; GO:0071320; GO:0071377; GO:0071400; GO:0071548; GO:0072341 18202 FUN_018008 2864 2249 1642 2847 2091 ptg000012l:3079482-3120350 P07756 1.42e-27 Carbamoyl-phosphate synthase [ammonia], mitochondrial (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I) Rattus norvegicus (Rat) 'de novo' pyrimidine nucleobase biosynthetic process [GO:0006207]; anion homeostasis [GO:0055081]; carbamoyl phosphate biosynthetic process [GO:0070409]; cellular response to ammonium ion [GO:0071242]; cellular response to cAMP [GO:0071320]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucagon stimulus [GO:0071377]; cellular response to oleic acid [GO:0071400]; glutamine metabolic process [GO:0006541]; hepatocyte differentiation [GO:0070365]; homocysteine metabolic process [GO:0050667]; liver development [GO:0001889]; midgut development [GO:0007494]; nitric oxide metabolic process [GO:0046209]; nitrogen compound metabolic process [GO:0006807]; response to amine [GO:0014075]; response to amino acid [GO:0043200]; response to cAMP [GO:0051591]; response to dexamethasone [GO:0071548]; response to food [GO:0032094]; response to glucagon [GO:0033762]; response to glucocorticoid [GO:0051384]; response to growth hormone [GO:0060416]; response to lipopolysaccharide [GO:0032496]; response to oleic acid [GO:0034201]; response to starvation [GO:0042594]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410]; response to zinc ion [GO:0010043]; sequestering of metal ion [GO:0051238]; triglyceride catabolic process [GO:0019433]; urea cycle [GO:0000050]; vasodilation [GO:0042311] GO:0000050; GO:0001889; GO:0004087; GO:0004088; GO:0004175; GO:0005509; GO:0005524; GO:0005543; GO:0005730; GO:0005737; GO:0005739; GO:0005743; GO:0006207; GO:0006541; GO:0006807; GO:0007494; GO:0009410; GO:0009636; GO:0010043; GO:0014075; GO:0016595; GO:0019433; GO:0032094; GO:0032496; GO:0032991; GO:0033762; GO:0034201; GO:0036094; GO:0042311; GO:0042594; GO:0042645; GO:0043200; GO:0044344; GO:0044877; GO:0046209; GO:0046872; GO:0048545; GO:0050667; GO:0051238; GO:0051384; GO:0051591; GO:0055081; GO:0060416; GO:0070365; GO:0070409; GO:0071242; GO:0071320; GO:0071377; GO:0071400; GO:0071548; GO:0072341 18203 FUN_018005 1233 589 784 756 1191 ptg000012l:3031394-3042990 P42124 1.48e-35 Histone-lysine N-methyltransferase E(z) (EC 2.1.1.356) (Lysine N-methyltransferase 6) (Protein enhancer of zeste) Drosophila melanogaster (Fruit fly) anterior/posterior axis specification [GO:0009948]; axon guidance [GO:0007411]; facultative heterochromatin formation [GO:0140718]; heterochromatin formation [GO:0031507]; histone H3-K27 trimethylation [GO:0098532]; negative regulation of DNA-templated transcription [GO:0045892]; neurogenesis [GO:0022008]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; syncytial blastoderm mitotic cell cycle [GO:0035186] GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0006357; GO:0007411; GO:0009948; GO:0022008; GO:0031507; GO:0035097; GO:0035098; GO:0035186; GO:0042054; GO:0043565; GO:0045892; GO:0046974; GO:0046976; GO:0098532; GO:0140718; GO:0140951; GO:1902692 18204 FUN_018005 1233 589 784 756 1191 ptg000012l:3031394-3042990 P42124 1.48e-35 Histone-lysine N-methyltransferase E(z) (EC 2.1.1.356) (Lysine N-methyltransferase 6) (Protein enhancer of zeste) Drosophila melanogaster (Fruit fly) anterior/posterior axis specification [GO:0009948]; axon guidance [GO:0007411]; facultative heterochromatin formation [GO:0140718]; heterochromatin formation [GO:0031507]; histone H3-K27 trimethylation [GO:0098532]; negative regulation of DNA-templated transcription [GO:0045892]; neurogenesis [GO:0022008]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; syncytial blastoderm mitotic cell cycle [GO:0035186] GO:0000785; GO:0003677; GO:0003682; GO:0005634; GO:0006357; GO:0007411; GO:0009948; GO:0022008; GO:0031507; GO:0035097; GO:0035098; GO:0035186; GO:0042054; GO:0043565; GO:0045892; GO:0046974; GO:0046976; GO:0098532; GO:0140718; GO:0140951; GO:1902692 18205 FUN_027820 0 34 0 0 0 NA NA NA NA NA NA NA 18206 FUN_018007 3879 3537 2697 3855 3270 NA NA NA NA NA NA NA 18207 FUN_018006 987 703 437 791 519 NA NA NA NA NA NA NA 18208 FUN_027825 36 0 0 0 0 NA NA NA NA NA NA NA 18209 FUN_018003 587 431 329 691 796 NA NA NA NA NA NA NA 18210 FUN_018002 0 0 19 0 28 NA NA NA NA NA NA NA 18211 FUN_010956 2645 1477 576 1764 1480 NA NA NA NA NA NA NA 18212 FUN_010954 185 195 278 47 147 NA NA NA NA NA NA NA 18213 FUN_023308 1362 994 746 977 984 NA NA NA NA NA NA NA 18214 FUN_023309 677 428 174 300 269 NA NA NA NA NA NA NA 18215 FUN_023304 354 438 330 436 354 NA NA NA NA NA NA NA 18216 FUN_010953 17 1 12 23 295 NA NA NA NA NA NA NA 18217 FUN_023306 2928 986 473 781 665 ptg000017l:6083675-6087854 Q3B8E3 1.41e-28 Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (EC 3.1.3.-) (EC 3.6.1.1) Xenopus laevis (African clawed frog) dephosphorylation [GO:0016311]; phosphate-containing compound metabolic process [GO:0006796] GO:0004427; GO:0005634; GO:0005829; GO:0006796; GO:0016311; GO:0016791; GO:0046872 18218 FUN_023307 4999 3607 2515 3549 2257 NA NA NA NA NA NA NA 18219 FUN_023300 16183 11577 4307 5312 4254 ptg000017l:6048637-6055214 P49724 1.33e-84 Ornithine aminotransferase, mitochondrial (EC 2.6.1.13) (Ornithine--oxo-acid aminotransferase) Drosophila ananassae (Fruit fly) L-proline biosynthetic process [GO:0055129] GO:0004587; GO:0005759; GO:0030170; GO:0050155; GO:0055129 18220 FUN_023301 1276 835 534 703 372 NA NA NA NA NA NA NA 18221 FUN_023302 683 372 322 510 295 NA NA NA NA NA NA NA 18222 FUN_025463 6573 6165 3797 5678 6412 ptg000019l:3011122-3020082 Q5R8D7 2.78e-26 26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0005524; GO:0005634; GO:0006511; GO:0016887; GO:0022624; GO:0036402 18223 FUN_025460 6043 7794 3378 4344 3161 ptg000019l:2986803-2990574 Q4R4R6 1.77e-46 Cell division control protein 42 homolog (EC 3.6.5.2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; establishment or maintenance of cell polarity [GO:0007163]; nervous system development [GO:0007399]; phagocytosis, engulfment [GO:0006911]; positive regulation of cytokinesis [GO:0032467]; positive regulation of pinocytosis [GO:0048549]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of filopodium assembly [GO:0051489]; small GTPase mediated signal transduction [GO:0007264] GO:0003925; GO:0005525; GO:0005737; GO:0005815; GO:0006911; GO:0007015; GO:0007163; GO:0007264; GO:0007399; GO:0009653; GO:0016020; GO:0030154; GO:0030496; GO:0031258; GO:0032467; GO:0043227; GO:0048549; GO:0051233; GO:0051489; GO:0051988; GO:0072686; GO:1900026 18224 FUN_025467 20 0 4 4 9 NA NA NA NA NA NA NA 18225 FUN_025466 22997 14690 10078 23336 19015 ptg000019l:3035271-3051793 Q9Z1A6 1.38e-47 Vigilin (High density lipoprotein-binding protein) (HDL-binding protein) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869] GO:0003729; GO:0005634; GO:0005737; GO:0005844; GO:0006869; GO:0008203; GO:0034364 18226 FUN_025466 22997 14690 10078 23336 19015 ptg000019l:3035271-3051793 Q9Z1A6 1.77e-21 Vigilin (High density lipoprotein-binding protein) (HDL-binding protein) Rattus norvegicus (Rat) cholesterol metabolic process [GO:0008203]; lipid transport [GO:0006869] GO:0003729; GO:0005634; GO:0005737; GO:0005844; GO:0006869; GO:0008203; GO:0034364 18227 FUN_000489 7298 3895 3921 7430 6336 ntLink_6:3556817-3611924 P0CT40 3.56e-83 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18228 FUN_025468 4 6 2 12 6 NA NA NA NA NA NA NA 18229 FUN_002417 0 0 95 6 0 NA NA NA NA NA NA NA 18230 FUN_011702 1583 1136 815 1016 649 NA NA NA NA NA NA NA 18231 FUN_002411 0 0 96 0 68 NA NA NA NA NA NA NA 18232 FUN_002410 206 196 312 355 621 NA NA NA NA NA NA NA 18233 FUN_008435 2420 2322 1826 1679 1006 NA NA NA NA NA NA NA 18234 FUN_002413 0 32 461 0 780 NA NA NA NA NA NA NA 18235 FUN_000229 517 439 408 290 932 ntLink_6:540613-542040 Q3ZBL9 6.15e-55 Cyclin-H Bos taurus (Bovine) cell cycle [GO:0007049]; phosphorylation of RNA polymerase II C-terminal domain [GO:0070816]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000079; GO:0005634; GO:0005675; GO:0006357; GO:0006366; GO:0007049; GO:0016538; GO:0070816; GO:0070985 18236 FUN_011709 1610 2751 1042 1886 1122 NA NA NA NA NA NA NA 18237 FUN_011708 8 44 7 25 19 NA NA NA NA NA NA NA 18238 FUN_008430 4808 4801 2305 3766 2713 NA NA NA NA NA NA NA 18239 FUN_002419 0 3 179 0 58 NA NA NA NA NA NA NA 18240 FUN_002418 8 0 1241 2 461 NA NA NA NA NA NA NA 18241 FUN_000220 206 75 81 161 284 NA NA NA NA NA NA NA 18242 FUN_000221 1656 1353 774 1405 1403 NA NA NA NA NA NA NA 18243 FUN_000222 660 377 332 421 292 NA NA NA NA NA NA NA 18244 FUN_019352 1639 769 488 598 290 NA NA NA NA NA NA NA 18245 FUN_019350 26 55 18 16 11 NA NA NA NA NA NA NA 18246 FUN_000223 1611 657 608 856 1131 NA NA NA NA NA NA NA 18247 FUN_019354 33 0 9 23 33 NA NA NA NA NA NA NA 18248 FUN_000224 464 390 99 423 407 NA NA NA NA NA NA NA 18249 FUN_035222 879 265 506 593 453 ptg000025l:5301293-5308340 Q501V0 7.51e-110 Serine/threonine-protein kinase H1 homolog (EC 2.7.11.1) Danio rerio (Zebrafish) (Brachydanio rerio) protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 18250 FUN_008438 2216 1509 1145 2082 1795 ptg000002l:11548085-11568361 D8VNS8 2.95e-32 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 18251 FUN_039879 3097 2343 1432 1858 1723 ptg000031l:1224434-1227810 Q9BYN0 7.51e-25 Sulfiredoxin-1 (EC 1.8.98.2) Homo sapiens (Human) cellular response to chemical stress [GO:0062197]; cellular response to oxidative stress [GO:0034599]; response to oxidative stress [GO:0006979] GO:0005524; GO:0005737; GO:0005829; GO:0006979; GO:0016667; GO:0032542; GO:0034599; GO:0062197 18252 FUN_039878 2446 2600 2246 1802 705 NA NA NA NA NA NA NA 18253 FUN_035223 25 13 0 8 0 NA NA NA NA NA NA NA 18254 FUN_033819 565 595 538 282 303 NA NA NA NA NA NA NA 18255 FUN_033818 8873 2252 2653 5093 2535 ptg000024l:1645787-1649369 B3EWY6 2.76e-78 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18256 FUN_033818 8873 2252 2653 5093 2535 ptg000024l:1645787-1649369 B3EWY6 1.34e-41 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18257 FUN_033818 8873 2252 2653 5093 2535 ptg000024l:1645787-1649369 B3EWY6 3.01e-36 Skeletal aspartic acid-rich protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 18258 FUN_033815 895 1976 431 772 569 ptg000024l:1633914-1638914 Q1PRL4 1.65e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 18259 FUN_033815 895 1976 431 772 569 ptg000024l:1633914-1638914 Q1PRL4 1.72e-27 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 18260 FUN_033815 895 1976 431 772 569 ptg000024l:1633914-1638914 Q1PRL4 4.24e-25 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 18261 FUN_033814 2774 2060 966 1872 1355 NA NA NA NA NA NA NA 18262 FUN_033817 68 236 139 258 61 NA NA NA NA NA NA NA 18263 FUN_033816 92 130 89 142 95 NA NA NA NA NA NA NA 18264 FUN_039875 1314 548 333 748 757 NA NA NA NA NA NA NA 18265 FUN_033810 1725 2437 774 1909 1028 NA NA NA NA NA NA NA 18266 FUN_033813 275 207 78 287 87 ptg000024l:1621012-1625236 Q1PRL4 4.47e-59 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 18267 FUN_033812 435 250 230 237 368 ptg000024l:1613177-1619266 A4IF63 8.41e-33 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 18268 FUN_033812 435 250 230 237 368 ptg000024l:1613177-1619266 A4IF63 6.45e-21 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Bos taurus (Bovine) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of neuron apoptotic process [GO:0043523] GO:0000209; GO:0004842; GO:0005737; GO:0008270; GO:0043161; GO:0043523; GO:0061630 18269 FUN_018913 15 0 22 0 13 NA NA NA NA NA NA NA 18270 FUN_041414 0 77 0 6 24 NA NA NA NA NA NA NA 18271 FUN_018911 71 27 124 140 91 NA NA NA NA NA NA NA 18272 FUN_018910 6 4 60 175 1001 NA NA NA NA NA NA NA 18273 FUN_018917 0 0 10 16 0 NA NA NA NA NA NA NA 18274 FUN_018916 0 2 3 9 3 NA NA NA NA NA NA NA 18275 FUN_018915 0 0 50 0 0 ptg000012l:15146703-15200600 Q99315 1.89e-26 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 18276 FUN_018915 0 0 50 0 0 ptg000012l:15146703-15200600 Q99315 1.89e-26 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 18277 FUN_007099 0 6 28 10 0 NA NA NA NA NA NA NA 18278 FUN_007096 42 32 7 24 12 NA NA NA NA NA NA NA 18279 FUN_007097 36 12 15 50 51 NA NA NA NA NA NA NA 18280 FUN_007092 1958 859 608 1033 1267 NA NA NA NA NA NA NA 18281 FUN_013936 0 0 0 0 25 NA NA NA NA NA NA NA 18282 FUN_007090 808 498 1519 3571 2403 NA NA NA NA NA NA NA 18283 FUN_007091 1737 173 657 1181 1912 NA NA NA NA NA NA NA 18284 FUN_005829 40 0 40 53 255 NA NA NA NA NA NA NA 18285 FUN_005825 1299 1364 821 1547 796 NA NA NA NA NA NA NA 18286 FUN_013930 17 38 30 17 34 NA NA NA NA NA NA NA 18287 FUN_005732 15 0 0 0 0 NA NA NA NA NA NA NA 18288 FUN_005821 1486 1018 548 1334 912 ptg000001l:4404980-4416914 P27398 7.14e-21 Calpain-D (EC 3.4.22.-) (Calcium-activated neutral proteinase D) (CANP D) (Small optic lobes protein) Drosophila melanogaster (Fruit fly) nervous system development [GO:0007399]; proteolysis [GO:0006508]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0004198; GO:0005737; GO:0006508; GO:0007399; GO:0007601; GO:0046872; GO:0050896 18289 FUN_005821 1486 1018 548 1334 912 ptg000001l:4404980-4416914 P27398 7.14e-21 Calpain-D (EC 3.4.22.-) (Calcium-activated neutral proteinase D) (CANP D) (Small optic lobes protein) Drosophila melanogaster (Fruit fly) nervous system development [GO:0007399]; proteolysis [GO:0006508]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0004198; GO:0005737; GO:0006508; GO:0007399; GO:0007601; GO:0046872; GO:0050896 18290 FUN_005820 0 85 14 22 19 NA NA NA NA NA NA NA 18291 FUN_005823 1029 1004 782 1174 568 NA NA NA NA NA NA NA 18292 FUN_041411 121 219 106 186 173 NA NA NA NA NA NA NA 18293 FUN_041412 25 10045 30 43 5137 NA NA NA NA NA NA NA 18294 FUN_041413 43 24 27 0 5 NA NA NA NA NA NA NA 18295 FUN_034894 9614 6845 5087 7826 5980 NA NA NA NA NA NA NA 18296 FUN_034895 3654 2071 2220 3369 3500 NA NA NA NA NA NA NA 18297 FUN_034896 2288 2017 1173 3711 1378 NA NA NA NA NA NA NA 18298 FUN_034897 157 0 0 0 0 NA NA NA NA NA NA NA 18299 FUN_034890 3543 1846 1742 3066 2836 NA NA NA NA NA NA NA 18300 FUN_034891 4570 3862 2314 6370 2566 NA NA NA NA NA NA NA 18301 FUN_034892 44387 59704 28601 64240 24731 ptg000025l:1253942-1257131 Q0P6D2 1.26e-22 Divergent protein kinase domain 1C (Protein FAM69C) Homo sapiens (Human) NA GO:0005789 18302 FUN_034893 413 585 328 894 369 NA NA NA NA NA NA NA 18303 FUN_041418 164 655 1234 875 2043 ptg000035l:3483948-3484806 R1CW23 1.59e-103 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 18304 FUN_034898 781 86 53 84 43 NA NA NA NA NA NA NA 18305 FUN_030399 6 0 6 1 26 ptg000023l:10774657-10775420 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18306 FUN_030393 0 0 3 0 11 ptg000023l:10762612-10763263 P84239 1.38e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18307 FUN_036755 4879 3563 2497 3530 2664 NA NA NA NA NA NA NA 18308 FUN_030391 8 0 9 0 20 ptg000023l:10758447-10759210 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18309 FUN_030397 7 0 6 0 24 ptg000023l:10770605-10771368 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18310 FUN_030395 5 0 7 0 28 ptg000023l:10766552-10767315 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18311 FUN_033837 330 520 158 340 299 ptg000024l:1765661-1766593 Q5RBA4 1.62e-35 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005509; GO:0005938; GO:0016459 18312 FUN_032792 0 0 14 16 9 NA NA NA NA NA NA NA 18313 FUN_033836 1532 1358 612 1066 685 NA NA NA NA NA NA NA 18314 FUN_033835 34 26 4 39 20 NA NA NA NA NA NA NA 18315 FUN_036759 16 16 24 50 22 NA NA NA NA NA NA NA 18316 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18317 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18318 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18319 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18320 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18321 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 0 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18322 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 1.78e-160 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18323 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 6.78e-43 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18324 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 4.75e-42 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18325 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 6.88e-42 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18326 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 1.02e-40 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18327 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 3.12e-39 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18328 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 2.76e-38 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18329 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 3.77e-38 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18330 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 3.74e-36 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18331 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 1.45e-33 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18332 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 1.83e-33 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18333 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 1.23e-32 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18334 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 2.02e-32 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18335 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 3.61e-31 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18336 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 5.61e-30 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18337 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 2.18e-29 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18338 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 8.57e-29 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18339 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 1.43e-28 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18340 FUN_039850 856 276 356 376 276 ptg000031l:875688-888412 P07207 2.05e-26 Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein] Drosophila melanogaster (Fruit fly) actin filament organization [GO:0007015]; asymmetric cell division [GO:0008356]; axon guidance [GO:0007411]; border follicle cell migration [GO:0007298]; cell dedifferentiation [GO:0043697]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; chaeta development [GO:0022416]; chaeta morphogenesis [GO:0008407]; compartment boundary maintenance [GO:0060289]; compound eye development [GO:0048749]; compound eye morphogenesis [GO:0001745]; compound eye retinal cell programmed cell death [GO:0046667]; crystal cell differentiation [GO:0042688]; defense response to insect [GO:0002213]; determination of adult lifespan [GO:0008340]; dorsal appendage formation [GO:0046843]; dorsal closure [GO:0007391]; dorsal/ventral axis specification [GO:0009950]; embryonic hemopoiesis [GO:0035162]; epithelial cell proliferation involved in Malpighian tubule morphogenesis [GO:0061331]; epithelial cell type specification, open tracheal system [GO:0035153]; eye-antennal disc development [GO:0035214]; eye-antennal disc morphogenesis [GO:0007455]; female germ-line stem cell population maintenance [GO:0036099]; follicle cell of egg chamber development [GO:0030707]; follicle cell of egg chamber migration [GO:0007297]; follicle cell of egg chamber stalk formation [GO:0030713]; foregut morphogenesis [GO:0007440]; formation of a compartment boundary [GO:0060288]; germ-line stem cell population maintenance [GO:0030718]; germ-line stem-cell niche homeostasis [GO:0060250]; germarium-derived egg chamber formation [GO:0007293]; glial cell differentiation [GO:0010001]; glial cell fate determination [GO:0007403]; glial cell migration [GO:0008347]; hemocyte proliferation [GO:0035172]; imaginal disc-derived leg joint morphogenesis [GO:0016348]; imaginal disc-derived leg morphogenesis [GO:0007480]; imaginal disc-derived leg segmentation [GO:0036011]; imaginal disc-derived male genitalia morphogenesis [GO:0048803]; imaginal disc-derived wing margin morphogenesis [GO:0008587]; imaginal disc-derived wing morphogenesis [GO:0007476]; imaginal disc-derived wing vein specification [GO:0007474]; intestinal stem cell homeostasis [GO:0036335]; lamellocyte differentiation [GO:0035171]; larval lymph gland hemopoiesis [GO:0035167]; lateral inhibition [GO:0046331]; leg disc morphogenesis [GO:0007478]; long-term memory [GO:0007616]; lymph gland development [GO:0048542]; Malpighian tubule tip cell differentiation [GO:0061382]; mesoderm development [GO:0007498]; morphogenesis of an epithelial fold [GO:0060571]; motor neuron axon guidance [GO:0008045]; muscle cell cellular homeostasis [GO:0046716]; muscle cell fate determination [GO:0007521]; myoblast development [GO:0048627]; negative regulation of cell-cell adhesion mediated by cadherin [GO:2000048]; negative regulation of compound eye photoreceptor development [GO:0045316]; negative regulation of gene expression [GO:0010629]; negative regulation of lamellocyte differentiation [GO:0035204]; negative regulation of neurogenesis [GO:0050768]; nervous system process [GO:0050877]; neuroblast development [GO:0014019]; neuroblast fate determination [GO:0007400]; neuroblast fate specification [GO:0014018]; neuroblast proliferation [GO:0007405]; neuron fate determination [GO:0048664]; neuron fate specification [GO:0048665]; neuronal stem cell population maintenance [GO:0097150]; Notch signaling pathway [GO:0007219]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oogenesis [GO:0048477]; peripheral nervous system development [GO:0007422]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of crystal cell differentiation [GO:0042691]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R1/R6 cell differentiation [GO:0048052]; R3/R4 cell differentiation [GO:0048056]; R7 cell differentiation [GO:0045466]; regulation of cardioblast cell fate specification [GO:0042686]; regulation of cell differentiation [GO:0045595]; regulation of filopodium assembly [GO:0051489]; regulation of glycolytic process [GO:0006110]; regulation of growth [GO:0040008]; regulation of mitotic cell cycle [GO:0007346]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of stem cell division [GO:2000035]; response to symbiont [GO:0009608]; retinal cell programmed cell death [GO:0046666]; second mitotic wave involved in compound eye morphogenesis [GO:0016330]; sensory organ development [GO:0007423]; sensory organ precursor cell fate determination [GO:0016360]; stem cell differentiation [GO:0048863]; wing disc dorsal/ventral pattern formation [GO:0048190]; wing disc pattern formation [GO:0035222] GO:0001745; GO:0002052; GO:0002213; GO:0003682; GO:0003713; GO:0004888; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005768; GO:0005769; GO:0005770; GO:0005783; GO:0005788; GO:0005796; GO:0005829; GO:0005886; GO:0005912; GO:0006110; GO:0007015; GO:0007219; GO:0007293; GO:0007297; GO:0007298; GO:0007346; GO:0007391; GO:0007400; GO:0007403; GO:0007405; GO:0007411; GO:0007422; GO:0007423; GO:0007440; GO:0007455; GO:0007474; GO:0007476; GO:0007478; GO:0007480; GO:0007498; GO:0007521; GO:0007616; GO:0008045; GO:0008284; GO:0008340; GO:0008347; GO:0008356; GO:0008407; GO:0008587; GO:0009608; GO:0009950; GO:0009986; GO:0010001; GO:0010628; GO:0010629; GO:0014018; GO:0014019; GO:0016020; GO:0016324; GO:0016330; GO:0016348; GO:0016360; GO:0022416; GO:0030139; GO:0030154; GO:0030707; GO:0030713; GO:0030718; GO:0030720; GO:0032991; GO:0035035; GO:0035153; GO:0035162; GO:0035167; GO:0035171; GO:0035172; GO:0035204; GO:0035214; GO:0035222; GO:0036011; GO:0036099; GO:0036335; GO:0040008; GO:0042686; GO:0042688; GO:0042691; GO:0043525; GO:0043697; GO:0045165; GO:0045316; GO:0045466; GO:0045595; GO:0045893; GO:0045944; GO:0046331; GO:0046666; GO:0046667; GO:0046716; GO:0046843; GO:0048052; GO:0048056; GO:0048190; GO:0048477; GO:0048542; GO:0048627; GO:0048664; GO:0048665; GO:0048749; GO:0048803; GO:0048863; GO:0050699; GO:0050767; GO:0050768; GO:0050877; GO:0051489; GO:0060250; GO:0060288; GO:0060289; GO:0060571; GO:0061331; GO:0061382; GO:0097150; GO:1900087; GO:1902692; GO:1990433; GO:2000035; GO:2000048 18341 FUN_036758 609 206 122 296 327 NA NA NA NA NA NA NA 18342 FUN_033833 3895 516 1147 909 2721 ptg000024l:1742964-1747801 Q6L8S8 1.66e-27 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 18343 FUN_033832 1144 2 263 14 382 NA NA NA NA NA NA NA 18344 FUN_033831 145 149 83 124 49 NA NA NA NA NA NA NA 18345 FUN_039854 132 62 118 52 163 NA NA NA NA NA NA NA 18346 FUN_006329 6196 3436 3093 4902 6033 ptg000001l:10944284-10957657 P09623 2.31e-29 Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) Sus scrofa (Pig) histone succinylation [GO:0106077] GO:0001669; GO:0004148; GO:0005634; GO:0005739; GO:0005759; GO:0031514; GO:0045252; GO:0050660; GO:0106077 18347 FUN_006328 2115 2049 1189 2257 2048 NA NA NA NA NA NA NA 18348 FUN_006327 5 9 0 19 22 NA NA NA NA NA NA NA 18349 FUN_006325 13 7 15 13 12 NA NA NA NA NA NA NA 18350 FUN_006324 208 406 254 209 148 NA NA NA NA NA NA NA 18351 FUN_006323 23 7 3 39 65 NA NA NA NA NA NA NA 18352 FUN_006322 0 0 0 0 19 ptg000001l:10920577-10923222 D3ZVM4 6.96e-28 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Rattus norvegicus (Rat) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0016567; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 18353 FUN_006321 373 631 159 439 270 NA NA NA NA NA NA NA 18354 FUN_006320 925 756 635 1397 861 ptg000001l:10891534-10914174 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 18355 FUN_006320 925 756 635 1397 861 ptg000001l:10891534-10914174 O15050 8.65e-32 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 18356 FUN_006320 925 756 635 1397 861 ptg000001l:10891534-10914174 O15050 1.51e-30 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 18357 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 8.02e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18358 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 8.02e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18359 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 3.38e-35 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18360 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 1.92e-33 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18361 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 1.93e-27 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18362 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 2.05e-25 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18363 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 7.83e-25 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18364 FUN_036944 6 9 11 654 2461 ptg000026l:3726521-3730365 P0CI65 9.75e-25 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 18365 FUN_022736 51 12 36 25 25 ptg000016l:12699231-12700114 P25291 1.05e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18366 FUN_036946 0 12 0 55 11 NA NA NA NA NA NA NA 18367 FUN_036947 2 13 7 91 9 NA NA NA NA NA NA NA 18368 FUN_036940 32 25 13 28 44 ptg000026l:3603194-3605983 Q9VQ56 6.53e-61 Fez family zinc finger protein erm (Earmuff) Drosophila melanogaster (Fruit fly) axon target recognition [GO:0007412]; axonogenesis involved in innervation [GO:0060385]; cell dedifferentiation [GO:0043697]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of neuroblast proliferation [GO:0007406]; photoreceptor cell axon guidance [GO:0072499]; positive regulation of gene expression [GO:0010628]; positive regulation of netrin-activated signaling pathway [GO:1902843]; positive regulation of neuron differentiation [GO:0045666]; regulation of neuroblast proliferation [GO:1902692]; regulation of neurogenesis [GO:0050767]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000976; GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0007406; GO:0007412; GO:0010628; GO:0010629; GO:0019827; GO:0043025; GO:0043565; GO:0043697; GO:0044295; GO:0045666; GO:0045892; GO:0046872; GO:0050767; GO:0060385; GO:0072499; GO:1902692; GO:1902843 18369 FUN_036941 427 262 208 374 188 ptg000026l:3608402-3614114 Q91W98 1.61e-25 Solute carrier family 15 member 4 (Peptide/histidine transporter 1) Mus musculus (Mouse) dipeptide import across plasma membrane [GO:0140206]; histidine transport [GO:0015817]; innate immune response [GO:0045087]; L-histidine transmembrane export from vacuole [GO:0089708]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; transmembrane transport [GO:0055085] GO:0005290; GO:0005765; GO:0010008; GO:0015031; GO:0015333; GO:0015647; GO:0015817; GO:0015835; GO:0016020; GO:0022857; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0055085; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0089708; GO:0140206 18370 FUN_036942 178 144 116 321 252 ptg000026l:3624030-3710003 P14381 2.46e-109 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 18371 FUN_036943 0 0 0 0 9 NA NA NA NA NA NA NA 18372 FUN_036948 139 26 37 214 76 ptg000026l:3749374-3755645 Q68F72 6.6e-33 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 18373 FUN_036948 139 26 37 214 76 ptg000026l:3749374-3755645 Q68F72 6.07e-21 Solute carrier family 15 member 4 Xenopus laevis (African clawed frog) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015835; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0140206 18374 FUN_036949 9 27 11 20 12 NA NA NA NA NA NA NA 18375 FUN_022735 52 14 37 23 25 ptg000016l:12698113-12698593 P25291 2.32e-29 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18376 FUN_009151 157 107 28 108 658 NA NA NA NA NA NA NA 18377 FUN_035765 2796 1985 928 991 1287 ptg000025l:11470419-11486909 P33991 3.32e-27 DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21) Homo sapiens (Human) DNA replication [GO:0006260]; DNA strand elongation involved in DNA replication [GO:0006271]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; mitotic DNA replication initiation [GO:1902975]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003678; GO:0003697; GO:0005524; GO:0005634; GO:0005654; GO:0006260; GO:0006268; GO:0006271; GO:0016020; GO:0016887; GO:0030174; GO:0042555; GO:0071162; GO:1902975 18378 FUN_035764 1398 1669 735 750 1066 NA NA NA NA NA NA NA 18379 FUN_035767 653 283 435 718 962 NA NA NA NA NA NA NA 18380 FUN_035766 12 0 5 3 31 NA NA NA NA NA NA NA 18381 FUN_035761 27 14 41 22 44 ptg000025l:11420526-11423779 Q63244 5.26e-36 Forkhead box protein Q1 (HNF-3/forkhead-like protein 1) (HFH-1) (Hepatocyte nuclear factor 3 forkhead homolog 1) Rattus norvegicus (Rat) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hair follicle morphogenesis [GO:0031069]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0009653; GO:0030154; GO:0031069; GO:0043524; GO:1990837 18382 FUN_035763 9116 8085 3923 8775 5280 NA NA NA NA NA NA NA 18383 FUN_035762 268 172 281 242 296 NA NA NA NA NA NA NA 18384 FUN_022731 170 40 102 50 105 ptg000016l:12691411-12694124 P25291 1.93e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18385 FUN_022731 170 40 102 50 105 ptg000016l:12691411-12694124 P25291 2.05e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18386 FUN_022731 170 40 102 50 105 ptg000016l:12691411-12694124 P25291 2.32e-25 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18387 FUN_035769 797 524 559 720 1399 NA NA NA NA NA NA NA 18388 FUN_035768 148 46 120 117 175 NA NA NA NA NA NA NA 18389 FUN_031448 178 123 69 0 58 ptg000023l:21549239-21563077 Q7RTR2 3.9e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18390 FUN_031448 178 123 69 0 58 ptg000023l:21549239-21563077 Q7RTR2 1.76e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18391 FUN_031448 178 123 69 0 58 ptg000023l:21549239-21563077 Q7RTR2 6.16e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18392 FUN_031448 178 123 69 0 58 ptg000023l:21549239-21563077 Q7RTR2 1.22e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18393 FUN_031449 292 88 73 98 101 ptg000023l:21576534-21578261 B1HPR6 9.59e-39 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Lysinibacillus sphaericus (strain C3-41) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 18394 FUN_031440 72 15 30 140 170 NA NA NA NA NA NA NA 18395 FUN_031441 11 5 21 0 10 NA NA NA NA NA NA NA 18396 FUN_036495 0 0 0 28 42 NA NA NA NA NA NA NA 18397 FUN_031444 1153 212 197 1191 249 ptg000023l:21466060-21484301 Q7RTR2 6.82e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18398 FUN_031444 1153 212 197 1191 249 ptg000023l:21466060-21484301 Q7RTR2 1.6e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18399 FUN_031444 1153 212 197 1191 249 ptg000023l:21466060-21484301 Q7RTR2 1.15e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18400 FUN_031446 39 14 44 123 37 NA NA NA NA NA NA NA 18401 FUN_036952 49 10 12 269 3 NA NA NA NA NA NA NA 18402 FUN_018978 0 0 0 0 20 NA NA NA NA NA NA NA 18403 FUN_001678 72 4 2 68 12 ntLink_6:14963591-14964419 Q8IN35 5.16e-27 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 18404 FUN_001679 0 0 0 29 3 ntLink_6:14966666-14968439 Q924H0 1.93e-31 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 18405 FUN_013922 138 36 51 261 284 NA NA NA NA NA NA NA 18406 FUN_001674 14 74 53 41 21 ntLink_6:14928379-14929474 C3ZQF9 1.97e-31 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 18407 FUN_001675 0 0 6 5 30 ntLink_6:14942668-14946184 Q924H0 5.5e-27 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 18408 FUN_001677 15 0 4 16 2 NA NA NA NA NA NA NA 18409 FUN_001670 8 0 0 9 0 NA NA NA NA NA NA NA 18410 FUN_001671 4350 1986 1845 4039 3482 ntLink_6:14890591-14915706 O60293 1.75e-30 Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2) Homo sapiens (Human) RNA processing [GO:0006396] GO:0000178; GO:0005615; GO:0005634; GO:0006396; GO:0046872 18411 FUN_001672 1 19 83 30 9 ntLink_6:14920560-14921691 Q9EQD2 8.72e-29 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 18412 FUN_001673 6 6 21 24 18 NA NA NA NA NA NA NA 18413 FUN_001219 918 695 468 779 459 ntLink_6:9924859-9926856 Q8BGF9 5.53e-65 Solute carrier family 25 member 44 Mus musculus (Mouse) branched-chain amino acid catabolic process [GO:0009083]; branched-chain amino acid transport [GO:0015803]; regulation of cold-induced thermogenesis [GO:0120161] GO:0005739; GO:0005743; GO:0009083; GO:0015658; GO:0015803; GO:0120161 18414 FUN_036232 2519 1680 1150 1570 993 NA NA NA NA NA NA NA 18415 FUN_036233 0 0 3 0 32 NA NA NA NA NA NA NA 18416 FUN_036230 942 870 526 698 783 ptg000025l:16821396-16846903 P04323 3.31e-72 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18417 FUN_036231 1601 1381 898 1572 1568 ptg000025l:16849867-16853175 Q8WTS1 2.42e-60 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) Homo sapiens (Human) cell differentiation [GO:0030154]; fatty acid metabolic process [GO:0006631]; lipid homeostasis [GO:0055088]; negative regulation of sequestering of triglyceride [GO:0010891]; phosphatidic acid biosynthetic process [GO:0006654]; positive regulation of lipoprotein lipase activity [GO:0051006]; positive regulation of triglyceride catabolic process [GO:0010898] GO:0003841; GO:0005654; GO:0005739; GO:0005811; GO:0005829; GO:0006631; GO:0006654; GO:0010891; GO:0010898; GO:0030154; GO:0042171; GO:0043231; GO:0051006; GO:0055088 18418 FUN_036236 335 356 357 633 334 ptg000025l:16942513-16959014 P97846 2.46e-33 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 18419 FUN_036236 335 356 357 633 334 ptg000025l:16942513-16959014 P97846 4.3e-33 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 18420 FUN_036237 968 1635 1298 1642 410 ptg000025l:16964566-16972512 P97846 5.81e-36 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 18421 FUN_036234 44 31 25 50 71 NA NA NA NA NA NA NA 18422 FUN_036235 576 208 308 498 622 NA NA NA NA NA NA NA 18423 FUN_029154 502 320 270 398 456 ptg000022l:8763585-8764487 Q86XH1 6.58e-31 Dynein regulatory complex protein 11 (IQ and AAA domain-containing protein 1) Homo sapiens (Human) NA GO:0005524; GO:0005737; GO:0005856; GO:0016887; GO:0031514 18424 FUN_037727 17 156 56 42 19 ptg000026l:12834597-12837005 O54991 3.32e-33 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 18425 FUN_037725 0 0 0 21 12 ptg000026l:12818828-12822497 O54991 3.32e-31 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 18426 FUN_037721 14 39 0 16 5 ptg000026l:12765628-12770613 Q9UHC6 1.25e-33 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 18427 FUN_000079 3 0 6 0 10 ntLink_4:78039-78818 P84239 4.85e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18428 FUN_000078 0 0 0 0 6 ntLink_4:75725-76920 P35061 7.49e-82 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18429 FUN_005009 0 0 0 6 0 NA NA NA NA NA NA NA 18430 FUN_005008 0 0 0 0 9 NA NA NA NA NA NA NA 18431 FUN_000075 2 0 5 0 7 ntLink_4:69464-71746 P84239 8.17e-87 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18432 FUN_005004 164 23 0 21 4 ntLink_8:29898521-29901393 Q9P2E3 8.71e-73 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 18433 FUN_005003 407 16 103 54 120 ntLink_8:29892498-29897563 Q8R151 0 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 18434 FUN_005003 407 16 103 54 120 ntLink_8:29892498-29897563 Q8R151 5.25e-25 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 18435 FUN_005001 86 30 43 43 90 NA NA NA NA NA NA NA 18436 FUN_001397 276 267 169 239 175 NA NA NA NA NA NA NA 18437 FUN_001396 4851 2608 2666 2673 1264 ntLink_6:11908587-11910717 O97562 1.37e-82 Dicarboxylate carrier SLC25A8 (Mitochondrial uncoupling protein 2) (UCP 2) (Solute carrier family 25 member 8) Sus scrofa (Pig) adaptive thermogenesis [GO:1990845]; C4-dicarboxylate transport [GO:0015740]; cellular response to glucose stimulus [GO:0071333]; glutamine metabolic process [GO:0006541]; glycolytic process [GO:0006096]; macrophage differentiation [GO:0030225]; mitochondrial fission [GO:0000266]; mitochondrial transmembrane transport [GO:1990542]; mitochondrial transport [GO:0006839]; reactive oxygen species metabolic process [GO:0072593]; response to cold [GO:0009409] GO:0000266; GO:0005743; GO:0006096; GO:0006541; GO:0006839; GO:0008271; GO:0009409; GO:0015078; GO:0015131; GO:0015140; GO:0015183; GO:0015297; GO:0015740; GO:0017077; GO:0022857; GO:0030225; GO:0042803; GO:0071333; GO:0072593; GO:0140787; GO:1990542; GO:1990845 18438 FUN_032805 15 11 34 32 54 NA NA NA NA NA NA NA 18439 FUN_032804 15 0 0 0 22 NA NA NA NA NA NA NA 18440 FUN_032806 78 89 47 79 92 NA NA NA NA NA NA NA 18441 FUN_032801 131 57 67 141 273 NA NA NA NA NA NA NA 18442 FUN_032800 89 13 53 55 68 ptg000023l:36055358-36056510 P43141 7.66e-29 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 18443 FUN_032803 77 55 15 43 63 NA NA NA NA NA NA NA 18444 FUN_032802 17 63 63 43 77 NA NA NA NA NA NA NA 18445 FUN_032809 0 0 3 4 11 NA NA NA NA NA NA NA 18446 FUN_031256 0 0 17 368 140 NA NA NA NA NA NA NA 18447 FUN_031252 1304 890 899 1721 754 NA NA NA NA NA NA NA 18448 FUN_006668 695 514 202 266 0 NA NA NA NA NA NA NA 18449 FUN_006669 67 2 1 17 1 NA NA NA NA NA NA NA 18450 FUN_008208 0 0 12 0 16 NA NA NA NA NA NA NA 18451 FUN_006662 740 1012 443 450 204 NA NA NA NA NA NA NA 18452 FUN_006663 16 44 29 19 46 NA NA NA NA NA NA NA 18453 FUN_006666 36 0 21 17 17 NA NA NA NA NA NA NA 18454 FUN_006667 176 38 20 32 0 NA NA NA NA NA NA NA 18455 FUN_008200 20 14 22 10 50 NA NA NA NA NA NA NA 18456 FUN_008201 858 885 267 562 458 NA NA NA NA NA NA NA 18457 FUN_022080 1023 497 538 1145 941 NA NA NA NA NA NA NA 18458 FUN_040492 518 299 259 560 559 NA NA NA NA NA NA NA 18459 FUN_043898 0 0 23 51 0 NA NA NA NA NA NA NA 18460 FUN_040491 668 592 340 930 792 ptg000031l:9296955-9306318 P28841 4.61e-32 Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2) Rattus norvegicus (Rat) enkephalin processing [GO:0034230]; insulin processing [GO:0030070]; islet amyloid polypeptide processing [GO:0034231]; nervous system development [GO:0007399]; peptide hormone processing [GO:0016486]; protein autoprocessing [GO:0016540]; protein processing [GO:0016485]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005615; GO:0005654; GO:0006508; GO:0007399; GO:0016020; GO:0016485; GO:0016486; GO:0016540; GO:0030070; GO:0030133; GO:0030141; GO:0030425; GO:0034230; GO:0034231; GO:0034774; GO:0043005; GO:0043025; GO:0043204 18461 FUN_031258 819 109 378 848 456 NA NA NA NA NA NA NA 18462 FUN_003523 28 0 49 0 0 NA NA NA NA NA NA NA 18463 FUN_003521 0 30 0 9 21 NA NA NA NA NA NA NA 18464 FUN_004758 0 77 71 68 95 NA NA NA NA NA NA NA 18465 FUN_004759 2847 603 538 1602 656 ntLink_8:26577233-26653579 P0CT40 2.07e-80 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18466 FUN_003525 0 0 0 19 0 NA NA NA NA NA NA NA 18467 FUN_010236 0 0 0 0 15 NA NA NA NA NA NA NA 18468 FUN_010237 5 3 1 187 9 NA NA NA NA NA NA NA 18469 FUN_003528 0 0 0 10 0 NA NA NA NA NA NA NA 18470 FUN_010235 0 2 11 3 48 NA NA NA NA NA NA NA 18471 FUN_004751 3599 941 692 1888 1225 ntLink_8:26496523-26506428 Q94688 1.17e-37 Aldehyde dehydrogenase 9 (EC 1.2.1.3) (PM-ALDH9) Polyandrocarpa misakiensis (Tunicate) ethanol catabolic process [GO:0006068] GO:0004029; GO:0006068; GO:0043878 18472 FUN_022086 27 0 19 0 0 NA NA NA NA NA NA NA 18473 FUN_010580 161 107 90 351 492 NA NA NA NA NA NA NA 18474 FUN_010581 253 213 13 177 112 NA NA NA NA NA NA NA 18475 FUN_010582 38 94 0 35 23 NA NA NA NA NA NA NA 18476 FUN_010583 1148 1342 624 699 321 ptg000007l:427576-434372 Q4VBH4 4.85e-23 Probable ubiquitin-conjugating enzyme E2 W-A (EC 2.3.2.25) (E2 ubiquitin-conjugating enzyme W-A) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.23) (Ubiquitin carrier protein W-A) (Ubiquitin-protein ligase W-A) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to misfolded protein [GO:0071218]; DNA repair [GO:0006281]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0006281; GO:0006513; GO:0006515; GO:0043161; GO:0061631; GO:0071218 18477 FUN_040264 70 34 0 11 9 NA NA NA NA NA NA NA 18478 FUN_010585 48 39 98 86 36 ptg000007l:443785-446197 Q9GRC0 2.85e-74 Serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) Patiria pectinifera (Starfish) (Asterina pectinifera) female gamete generation [GO:0007292]; female meiosis II [GO:0007147]; negative regulation of mitotic cell cycle [GO:0045930]; protein phosphorylation [GO:0006468] GO:0004709; GO:0005524; GO:0006468; GO:0007147; GO:0007292; GO:0045930; GO:0106310 18479 FUN_010586 708 745 416 437 596 NA NA NA NA NA NA NA 18480 FUN_010587 875 563 243 584 963 NA NA NA NA NA NA NA 18481 FUN_040269 357 274 29 331 0 NA NA NA NA NA NA NA 18482 FUN_034409 12 0 21 0 25 NA NA NA NA NA NA NA 18483 FUN_034408 15 17 6 36 23 NA NA NA NA NA NA NA 18484 FUN_034407 110 255 140 64 432 NA NA NA NA NA NA NA 18485 FUN_034406 54 354 234 138 420 NA NA NA NA NA NA NA 18486 FUN_034405 273 651 434 209 635 NA NA NA NA NA NA NA 18487 FUN_034403 752 193 375 295 129 ptg000024l:8477599-8506033 Q95SX7 3.15e-31 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 18488 FUN_034401 11 0 26 0 34 NA NA NA NA NA NA NA 18489 FUN_034400 17 22 4 36 58 NA NA NA NA NA NA NA 18490 FUN_023287 0 0 36 14 42 NA NA NA NA NA NA NA 18491 FUN_002693 18 30 33 29 38 NA NA NA NA NA NA NA 18492 FUN_002692 972 367 334 475 606 NA NA NA NA NA NA NA 18493 FUN_002691 230 63 102 108 114 NA NA NA NA NA NA NA 18494 FUN_002690 60 0 0 43 164 NA NA NA NA NA NA NA 18495 FUN_002697 1885 1151 1004 1898 2634 ntLink_8:5525321-5527191 Q3KPT7 2.51e-63 Dehydrogenase/reductase SDR family member 6 (EC 1.1.1.-) ((R)-beta-hydroxybutyrate dehydrogenase) (3-hydroxybutyrate dehydrogenase type 2) (EC 1.1.1.30) (4-oxo-L-proline reductase) (EC 1.1.1.104) (Oxidoreductase UCPA) (Short chain dehydrogenase/reductase family 15C member 1) Xenopus laevis (African clawed frog) heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; lipid metabolic process [GO:0006629]; siderophore biosynthetic process [GO:0019290] GO:0003858; GO:0005737; GO:0006629; GO:0016617; GO:0016628; GO:0019290; GO:0042168; GO:0055072 18496 FUN_002697 1885 1151 1004 1898 2634 ntLink_8:5525321-5527191 Q3KPT7 5.87e-27 Dehydrogenase/reductase SDR family member 6 (EC 1.1.1.-) ((R)-beta-hydroxybutyrate dehydrogenase) (3-hydroxybutyrate dehydrogenase type 2) (EC 1.1.1.30) (4-oxo-L-proline reductase) (EC 1.1.1.104) (Oxidoreductase UCPA) (Short chain dehydrogenase/reductase family 15C member 1) Xenopus laevis (African clawed frog) heme metabolic process [GO:0042168]; iron ion homeostasis [GO:0055072]; lipid metabolic process [GO:0006629]; siderophore biosynthetic process [GO:0019290] GO:0003858; GO:0005737; GO:0006629; GO:0016617; GO:0016628; GO:0019290; GO:0042168; GO:0055072 18497 FUN_002696 1535 936 610 1370 1318 NA NA NA NA NA NA NA 18498 FUN_002694 9 9 4 0 14 NA NA NA NA NA NA NA 18499 FUN_011187 647 23 214 77 36 NA NA NA NA NA NA NA 18500 FUN_002698 357 168 27 200 186 NA NA NA NA NA NA NA 18501 FUN_011183 0 51 0 0 45 NA NA NA NA NA NA NA 18502 FUN_011182 0 26 0 49 14 NA NA NA NA NA NA NA 18503 FUN_040848 0 0 0 48 10 NA NA NA NA NA NA NA 18504 FUN_040849 14 23 4 12 97 NA NA NA NA NA NA NA 18505 FUN_040844 0 0 0 16 0 NA NA NA NA NA NA NA 18506 FUN_040845 16 0 9 0 9 NA NA NA NA NA NA NA 18507 FUN_040847 0 0 0 17 14 NA NA NA NA NA NA NA 18508 FUN_040840 0 0 19 0 64 ptg000031l:13255237-13256120 Q94K49 6.31e-25 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 18509 FUN_040840 0 0 19 0 64 ptg000031l:13255237-13256120 Q94K49 6.31e-25 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 18510 FUN_040843 690 0 64 379 388 NA NA NA NA NA NA NA 18511 FUN_002345 555 47 55 882 353 ntLink_8:301635-305307 Q96AY4 1.23e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18512 FUN_002345 555 47 55 882 353 ntLink_8:301635-305307 Q96AY4 1.02e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18513 FUN_002345 555 47 55 882 353 ntLink_8:301635-305307 Q96AY4 1.76e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18514 FUN_002345 555 47 55 882 353 ntLink_8:301635-305307 Q96AY4 1.75e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18515 FUN_002347 0 0 0 0 10 NA NA NA NA NA NA NA 18516 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 5.31e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18517 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 1.26e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18518 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 2.93e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18519 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 3.11e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18520 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 7.01e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18521 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 3.12e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18522 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 5.07e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18523 FUN_002346 235 266 2351 1863 1677 ntLink_8:334350-352449 Q80XJ3 1.38e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 18524 FUN_002341 836 10 87 874 727 ntLink_8:269857-274198 Q96AY4 2e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18525 FUN_002341 836 10 87 874 727 ntLink_8:269857-274198 Q96AY4 1.28e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18526 FUN_002341 836 10 87 874 727 ntLink_8:269857-274198 Q96AY4 1.84e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18527 FUN_002341 836 10 87 874 727 ntLink_8:269857-274198 Q96AY4 1.09e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18528 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 9.11e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18529 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 1.21e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18530 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 4.37e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18531 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 3.66e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18532 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 5.49e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18533 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 3.54e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18534 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 1.18e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18535 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 3.38e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18536 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 2.11e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18537 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 5.05e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18538 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 6.25e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18539 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 2.73e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18540 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 2.45e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18541 FUN_002340 1348 0 115 667 528 ntLink_8:211296-264848 Q96AY4 1.13e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18542 FUN_002343 43 0 0 2 62 NA NA NA NA NA NA NA 18543 FUN_002342 164 39 1 61 59 NA NA NA NA NA NA NA 18544 FUN_002349 16 13 16 106 6 NA NA NA NA NA NA NA 18545 FUN_022817 10 0 71 0 85 NA NA NA NA NA NA NA 18546 FUN_022816 423 29 272 105 90 NA NA NA NA NA NA NA 18547 FUN_022815 2833 3282 1149 1984 1597 NA NA NA NA NA NA NA 18548 FUN_022814 154 121 159 319 155 NA NA NA NA NA NA NA 18549 FUN_022813 3304 2546 1699 1979 2009 NA NA NA NA NA NA NA 18550 FUN_022812 4148 3174 1992 2994 2443 NA NA NA NA NA NA NA 18551 FUN_022811 55 95 44 59 124 NA NA NA NA NA NA NA 18552 FUN_022810 899 500 619 491 219 NA NA NA NA NA NA NA 18553 FUN_022819 12 31 9 28 24 NA NA NA NA NA NA NA 18554 FUN_022818 2420 1279 1367 2197 2233 NA NA NA NA NA NA NA 18555 FUN_029791 7 0 0 0 0 NA NA NA NA NA NA NA 18556 FUN_029795 0 19 0 2 23 NA NA NA NA NA NA NA 18557 FUN_029794 0 0 0 14 0 NA NA NA NA NA NA NA 18558 FUN_029797 0 0 0 0 8 NA NA NA NA NA NA NA 18559 FUN_029796 5 39 7 107 56 NA NA NA NA NA NA NA 18560 FUN_016326 3504 4466 2085 4151 2026 NA NA NA NA NA NA NA 18561 FUN_016327 441 478 276 697 300 NA NA NA NA NA NA NA 18562 FUN_016324 673 650 558 802 423 ptg000011l:1628476-1634200 Q8BTM8 5.12e-31 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Mus musculus (Mouse) actin crosslink formation [GO:0051764]; actin cytoskeleton organization [GO:0030036]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; establishment of Sertoli cell barrier [GO:0097368]; formation of radial glial scaffolds [GO:0021943]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; mRNA transcription by RNA polymerase II [GO:0042789]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; positive regulation of actin filament bundle assembly [GO:0032233]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuron migration [GO:2001224]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to bicellular tight junction [GO:1902396]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003779; GO:0005080; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016479; GO:0019900; GO:0021943; GO:0030018; GO:0030036; GO:0030334; GO:0030426; GO:0030863; GO:0031267; GO:0031523; GO:0031532; GO:0031852; GO:0032231; GO:0032233; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042789; GO:0042803; GO:0043025; GO:0043066; GO:0043113; GO:0043123; GO:0043198; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0044877; GO:0045022; GO:0045184; GO:0045216; GO:0046332; GO:0048471; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0097368; GO:0097440; GO:0098794; GO:0098978; GO:0140297; GO:1900026; GO:1901381; GO:1902396; GO:1905000; GO:1905031; GO:1990779; GO:2000179; GO:2001046; GO:2001224 18563 FUN_016325 493 198 200 457 416 NA NA NA NA NA NA NA 18564 FUN_016322 778 662 424 673 535 NA NA NA NA NA NA NA 18565 FUN_016323 972 740 561 1096 1065 NA NA NA NA NA NA NA 18566 FUN_016320 871 427 517 707 626 NA NA NA NA NA NA NA 18567 FUN_016321 413 161 217 460 504 NA NA NA NA NA NA NA 18568 FUN_016328 141 35 0 94 41 NA NA NA NA NA NA NA 18569 FUN_016329 2106 1887 1414 1956 1632 NA NA NA NA NA NA NA 18570 FUN_023142 67 10 53 24 111 ptg000017l:4118358-4119516 E7F7V7 2.27e-22 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 18571 FUN_026311 13 2 13 16 4 NA NA NA NA NA NA NA 18572 FUN_026313 134 56 0 196 29 ptg000020l:7677604-7688008 P25291 4.56e-24 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18573 FUN_026313 134 56 0 196 29 ptg000020l:7677604-7688008 P25291 6.16e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18574 FUN_026313 134 56 0 196 29 ptg000020l:7677604-7688008 P25291 9.82e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18575 FUN_026313 134 56 0 196 29 ptg000020l:7677604-7688008 P25291 1.67e-22 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18576 FUN_026313 134 56 0 196 29 ptg000020l:7677604-7688008 P25291 7.16e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 18577 FUN_023146 31 0 0 0 0 NA NA NA NA NA NA NA 18578 FUN_023147 0 0 0 0 25 NA NA NA NA NA NA NA 18579 FUN_026317 75 9 6 0 3 NA NA NA NA NA NA NA 18580 FUN_026318 69 10 7 0 5 NA NA NA NA NA NA NA 18581 FUN_026319 56 7 6 0 4 NA NA NA NA NA NA NA 18582 FUN_023149 51 36 64 205 55 NA NA NA NA NA NA NA 18583 FUN_025661 12164 9201 4046 8026 6520 ptg000019l:5405565-5412857 Q5ZMP6 3.75e-38 AP-2 complex subunit mu (AP-2 mu chain) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein) Gallus gallus (Chicken) clathrin-dependent endocytosis [GO:0072583]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0006886; GO:0006897; GO:0008289; GO:0016192; GO:0030122; GO:0031410; GO:0035615; GO:0072583 18584 FUN_025660 1711 1050 847 1546 1670 NA NA NA NA NA NA NA 18585 FUN_025663 2227 2537 1449 2579 1391 ptg000019l:5421258-5427011 Q9UPW0 1.07e-41 Forkhead box protein J3 Homo sapiens (Human) cell differentiation [GO:0030154]; male meiosis I [GO:0007141]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0007141; GO:0007283; GO:0030154; GO:0043565; GO:0045944; GO:1990837 18586 FUN_025662 7196 6129 3708 7019 4757 NA NA NA NA NA NA NA 18587 FUN_025665 91 129 91 69 117 NA NA NA NA NA NA NA 18588 FUN_025664 0 0 4 0 17 NA NA NA NA NA NA NA 18589 FUN_025667 2154 1676 1219 1446 1429 NA NA NA NA NA NA NA 18590 FUN_025666 2365 1960 1016 1659 847 NA NA NA NA NA NA NA 18591 FUN_025669 1271 1931 666 943 653 ptg000019l:5459482-5462461 Q567I9 3.91e-30 Cytochrome b5 domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0046872 18592 FUN_025668 1184 862 383 957 819 NA NA NA NA NA NA NA 18593 FUN_007173 17 6 0 0 8 NA NA NA NA NA NA NA 18594 FUN_017749 1 0 2 8 10 NA NA NA NA NA NA NA 18595 FUN_017748 0 0 4 6 3 NA NA NA NA NA NA NA 18596 FUN_028446 1044 1389 504 2696 2189 NA NA NA NA NA NA NA 18597 FUN_023495 170 119 198 174 216 NA NA NA NA NA NA NA 18598 FUN_028444 605 436 310 1907 269 ptg000021l:19978127-20039040 P20825 1.19e-87 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18599 FUN_028444 605 436 310 1907 269 ptg000021l:19978127-20039040 P20825 2.01e-28 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18600 FUN_028444 605 436 310 1907 269 ptg000021l:19978127-20039040 P20825 4.5e-26 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18601 FUN_028444 605 436 310 1907 269 ptg000021l:19978127-20039040 P20825 4.5e-26 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18602 FUN_028444 605 436 310 1907 269 ptg000021l:19978127-20039040 P20825 4.5e-26 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 18603 FUN_023497 3666 2365 1678 2780 2386 ptg000017l:8212018-8221013 Q7T292 9.81e-54 Mitoferrin-2 (Mitochondrial iron transporter 2) (Solute carrier family 25 member 28) Danio rerio (Zebrafish) (Brachydanio rerio) iron import into the mitochondrion [GO:0048250]; iron ion homeostasis [GO:0055072] GO:0005743; GO:0015093; GO:0031966; GO:0048250; GO:0055072 18604 FUN_028442 72 32 288 85 13 NA NA NA NA NA NA NA 18605 FUN_028440 0 8 0 0 16 NA NA NA NA NA NA NA 18606 FUN_028441 2 3 29 9 15 NA NA NA NA NA NA NA 18607 FUN_007172 6500 2863 3099 5511 4519 ptg000001l:21254546-21263750 O16025 3.06e-43 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 18608 FUN_007172 6500 2863 3099 5511 4519 ptg000001l:21254546-21263750 O16025 1.54e-36 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 18609 FUN_007172 6500 2863 3099 5511 4519 ptg000001l:21254546-21263750 O16025 2.43e-31 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 18610 FUN_007172 6500 2863 3099 5511 4519 ptg000001l:21254546-21263750 O16025 2.14e-24 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 18611 FUN_023498 1023 1045 453 694 717 NA NA NA NA NA NA NA 18612 FUN_023499 962 894 871 1357 1951 ptg000017l:8235898-8259190 Q8K1X1 1.02e-50 WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; head development [GO:0060322]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; multicellular organism growth [GO:0035264]; regulation of smoothened signaling pathway [GO:0008589]; vesicle tethering to Golgi [GO:0099041] GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005929; GO:0005930; GO:0006886; GO:0007507; GO:0008589; GO:0015630; GO:0031410; GO:0035264; GO:0036064; GO:0060271; GO:0060322; GO:0099041 18613 FUN_023499 962 894 871 1357 1951 ptg000017l:8235898-8259190 Q8K1X1 8.12e-31 WD repeat-containing protein 11 (Bromodomain and WD repeat-containing protein 2) Mus musculus (Mouse) cilium assembly [GO:0060271]; head development [GO:0060322]; heart development [GO:0007507]; intracellular protein transport [GO:0006886]; multicellular organism growth [GO:0035264]; regulation of smoothened signaling pathway [GO:0008589]; vesicle tethering to Golgi [GO:0099041] GO:0005634; GO:0005737; GO:0005802; GO:0005829; GO:0005929; GO:0005930; GO:0006886; GO:0007507; GO:0008589; GO:0015630; GO:0031410; GO:0035264; GO:0036064; GO:0060271; GO:0060322; GO:0099041 18614 FUN_028448 1983 1332 784 1376 703 ptg000021l:20087496-20107030 Q95SX7 2.4e-25 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 18615 FUN_028449 1020 527 928 720 716 NA NA NA NA NA NA NA 18616 FUN_022365 1584 1097 915 1524 1544 NA NA NA NA NA NA NA 18617 FUN_022364 1487 649 786 2656 2027 ptg000016l:8143209-8158772 P21803 2.09e-21 Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (Keratinocyte growth factor receptor) (KGFR) (CD antigen CD332) Mus musculus (Mouse) angiogenesis [GO:0001525]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; axonogenesis [GO:0007409]; bone development [GO:0060348]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; branch elongation involved in salivary gland morphogenesis [GO:0060667]; branching involved in labyrinthine layer morphogenesis [GO:0060670]; branching involved in prostate gland morphogenesis [GO:0060442]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of a nerve [GO:0048755]; bud elongation involved in lung branching [GO:0060449]; canonical Wnt signaling pathway [GO:0060070]; cardiac muscle cell proliferation [GO:0060038]; cell division [GO:0051301]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; coronal suture morphogenesis [GO:0060365]; digestive tract development [GO:0048565]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic organ development [GO:0048568]; embryonic organ morphogenesis [GO:0048562]; embryonic pattern specification [GO:0009880]; endodermal digestive tract morphogenesis [GO:0061031]; epidermis morphogenesis [GO:0048730]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; epithelial cell proliferation involved in salivary gland morphogenesis [GO:0060664]; epithelial to mesenchymal transition [GO:0001837]; epithelial tube branching involved in lung morphogenesis [GO:0060441]; ERK1 and ERK2 cascade [GO:0070371]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in hemopoiesis [GO:0035603]; fibroblast growth factor receptor signaling pathway involved in mammary gland specification [GO:0060595]; fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell [GO:0035602]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow [GO:0035604]; gland morphogenesis [GO:0022612]; hair follicle morphogenesis [GO:0031069]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lacrimal gland development [GO:0032808]; lateral sprouting from an epithelium [GO:0060601]; lens fiber cell development [GO:0070307]; limb bud formation [GO:0060174]; lung alveolus development [GO:0048286]; lung development [GO:0030324]; lung lobe morphogenesis [GO:0060463]; lung-associated mesenchyme development [GO:0060484]; mammary gland bud formation [GO:0060615]; membranous septum morphogenesis [GO:0003149]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell differentiation involved in lung development [GO:0060915]; mesenchymal cell proliferation [GO:0010463]; mesenchymal cell proliferation involved in lung development [GO:0060916]; midbrain development [GO:0030901]; mitotic nuclear division [GO:0140014]; morphogenesis of embryonic epithelium [GO:0016331]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular junction development [GO:0007528]; odontogenesis [GO:0042476]; orbitofrontal cortex development [GO:0021769]; organ growth [GO:0035265]; otic vesicle formation [GO:0030916]; outflow tract septum morphogenesis [GO:0003148]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of epithelial cell proliferation involved in lung morphogenesis [GO:0060501]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of somatic stem cell division [GO:1904677]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of urothelial cell proliferation [GO:0050677]; positive regulation of Wnt signaling pathway [GO:0030177]; post-embryonic development [GO:0009791]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; prostate epithelial cord elongation [GO:0060523]; prostate gland morphogenesis [GO:0060512]; protein autophosphorylation [GO:0046777]; pyramidal neuron development [GO:0021860]; regulation of epithelial cell proliferation [GO:0050678]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of morphogenesis of a branching structure [GO:0060688]; regulation of osteoblast proliferation [GO:0033688]; regulation of smooth muscle cell differentiation [GO:0051150]; regulation of smoothened signaling pathway [GO:0008589]; reproductive structure development [GO:0048608]; somatic stem cell division [GO:0048103]; squamous basal epithelial stem cell differentiation involved in prostate gland acinus development [GO:0060529]; stem cell differentiation [GO:0048863]; stem cell proliferation [GO:0072089]; synaptic vesicle transport [GO:0048489]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; urothelial cell proliferation [GO:0050674]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular cardiac muscle tissue morphogenesis [GO:0055010]; ventricular zone neuroblast division [GO:0021847] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001837; GO:0002053; GO:0003148; GO:0003149; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005794; GO:0005886; GO:0005938; GO:0006915; GO:0007169; GO:0007267; GO:0007409; GO:0007528; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0008589; GO:0009791; GO:0009880; GO:0009887; GO:0009986; GO:0010463; GO:0010518; GO:0010628; GO:0010839; GO:0016331; GO:0017134; GO:0018108; GO:0021769; GO:0021847; GO:0021860; GO:0022612; GO:0030177; GO:0030282; GO:0030324; GO:0030855; GO:0030901; GO:0030916; GO:0031069; GO:0031410; GO:0032808; GO:0033674; GO:0033688; GO:0035265; GO:0035602; GO:0035603; GO:0035604; GO:0035607; GO:0042472; GO:0042476; GO:0042802; GO:0042803; GO:0043235; GO:0043410; GO:0045165; GO:0045787; GO:0045839; GO:0045944; GO:0046777; GO:0048103; GO:0048286; GO:0048489; GO:0048557; GO:0048562; GO:0048565; GO:0048568; GO:0048608; GO:0048661; GO:0048701; GO:0048730; GO:0048755; GO:0048762; GO:0048863; GO:0050673; GO:0050674; GO:0050677; GO:0050678; GO:0050679; GO:0050680; GO:0051150; GO:0051301; GO:0055010; GO:0060038; GO:0060045; GO:0060070; GO:0060076; GO:0060174; GO:0060348; GO:0060349; GO:0060365; GO:0060441; GO:0060442; GO:0060445; GO:0060449; GO:0060463; GO:0060484; GO:0060501; GO:0060512; GO:0060523; GO:0060527; GO:0060529; GO:0060595; GO:0060601; GO:0060615; GO:0060664; GO:0060667; GO:0060670; GO:0060688; GO:0060915; GO:0060916; GO:0060979; GO:0061031; GO:0062023; GO:0070307; GO:0070371; GO:0070372; GO:0070374; GO:0072089; GO:0090263; GO:0140014; GO:1904677; GO:2000648 18618 FUN_022367 380 195 561 331 292 ptg000016l:8214813-8224886 P53603 6.68e-23 Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] Sus scrofa (Pig) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005542; GO:0005794; GO:0005814; GO:0005829; GO:0006548; GO:0019556; GO:0019557; GO:0030409; GO:0030412 18619 FUN_022366 24 0 0 0 76 NA NA NA NA NA NA NA 18620 FUN_022361 99 142 0 41 248 NA NA NA NA NA NA NA 18621 FUN_022360 23 0 0 0 24 NA NA NA NA NA NA NA 18622 FUN_022363 911 558 277 807 680 ptg000016l:8126573-8139687 A2RT91 0 Ankyrin and armadillo repeat-containing protein Mus musculus (Mouse) NA GO:0016020 18623 FUN_022363 911 558 277 807 680 ptg000016l:8126573-8139687 A2RT91 2.9e-21 Ankyrin and armadillo repeat-containing protein Mus musculus (Mouse) NA GO:0016020 18624 FUN_022362 42 0 0 45 29 NA NA NA NA NA NA NA 18625 FUN_013986 17 24 0 0 101 NA NA NA NA NA NA NA 18626 FUN_022369 426 302 257 456 633 ptg000016l:8232701-8249424 O08832 1.59e-33 Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) Mus musculus (Mouse) protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018242; GO:0018243; GO:0030145; GO:0030246; GO:0048471 18627 FUN_022369 426 302 257 456 633 ptg000016l:8232701-8249424 O08832 4.6e-26 Polypeptide N-acetylgalactosaminyltransferase 4 (EC 2.4.1.41) (Polypeptide GalNAc transferase 4) (GalNAc-T4) (pp-GaNTase 4) (Protein-UDP acetylgalactosaminyltransferase 4) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4) Mus musculus (Mouse) protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via serine [GO:0018242]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018242; GO:0018243; GO:0030145; GO:0030246; GO:0048471 18628 FUN_022368 334 230 90 210 319 ptg000016l:8225032-8230756 Q6NSI4 3.57e-35 RPA-related protein RADX (RPA-related and RAD51-antagonist, X-chromosome) Homo sapiens (Human) negative regulation of double-strand break repair via homologous recombination [GO:2000042]; regulation of DNA repair [GO:0006282] GO:0003697; GO:0003723; GO:0005657; GO:0006282; GO:0016607; GO:2000042 18629 FUN_011968 61 29 81 0 114 NA NA NA NA NA NA NA 18630 FUN_011961 6588 7840 3879 7837 2854 ptg000008l:3581064-3586287 Q5ZID0 1.28e-25 NmrA-like family domain-containing protein 1 Gallus gallus (Chicken) NA GO:0005634; GO:0048471 18631 FUN_011960 1038 823 515 906 494 NA NA NA NA NA NA NA 18632 FUN_011963 3388 3475 2719 3362 2456 NA NA NA NA NA NA NA 18633 FUN_011962 25913 33291 31409 24140 12024 NA NA NA NA NA NA NA 18634 FUN_011965 140 99 86 75 304 NA NA NA NA NA NA NA 18635 FUN_011964 3034 1037 1087 2879 4022 NA NA NA NA NA NA NA 18636 FUN_011967 134 24 54 16 694 NA NA NA NA NA NA NA 18637 FUN_011966 177 98 242 99 133 NA NA NA NA NA NA NA 18638 FUN_016160 185 51 28 187 205 NA NA NA NA NA NA NA 18639 FUN_042241 9 0 0 0 0 NA NA NA NA NA NA NA 18640 FUN_042242 7 0 5 0 7 NA NA NA NA NA NA NA 18641 FUN_016163 1982 1225 993 1826 1379 ptg000010l:2267282-2284790 Q8CDM1 6.29e-38 ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0016887; GO:0042393; GO:0045893; GO:0045944 18642 FUN_016163 1982 1225 993 1826 1379 ptg000010l:2267282-2284790 Q8CDM1 2.01e-34 ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0016887; GO:0042393; GO:0045893; GO:0045944 18643 FUN_016163 1982 1225 993 1826 1379 ptg000010l:2267282-2284790 Q8CDM1 2.11e-21 ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) Mus musculus (Mouse) positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0016887; GO:0042393; GO:0045893; GO:0045944 18644 FUN_016164 67 73 69 46 56 NA NA NA NA NA NA NA 18645 FUN_042245 21 0 7 3 270 NA NA NA NA NA NA NA 18646 FUN_014214 24 0 0 0 0 NA NA NA NA NA NA NA 18647 FUN_044175 5 4 37 17 199 NA NA NA NA NA NA NA 18648 FUN_044176 2 1 8 6 16 NA NA NA NA NA NA NA 18649 FUN_014217 7 12 14 15 55 NA NA NA NA NA NA NA 18650 FUN_014210 477 310 8 18 4 NA NA NA NA NA NA NA 18651 FUN_044171 4 12 37 44 126 NA NA NA NA NA NA NA 18652 FUN_044173 5 8 40 43 234 NA NA NA NA NA NA NA 18653 FUN_038076 0 0 0 0 134 NA NA NA NA NA NA NA 18654 FUN_044179 0 2 9 5 7 NA NA NA NA NA NA NA 18655 FUN_035298 599 406 200 210 117 NA NA NA NA NA NA NA 18656 FUN_024208 25424 30486 16167 24702 16080 ptg000018l:3350243-3454340 Q7RTR2 2.95e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18657 FUN_024208 25424 30486 16167 24702 16080 ptg000018l:3350243-3454340 Q7RTR2 3.34e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18658 FUN_024208 25424 30486 16167 24702 16080 ptg000018l:3350243-3454340 Q7RTR2 9.19e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 18659 FUN_024209 227 98 92 43 67 ptg000018l:3471576-3474971 A6QLE5 3.01e-35 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Bos taurus (Bovine) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 18660 FUN_024200 2265 1712 1278 1793 1393 NA NA NA NA NA NA NA 18661 FUN_024201 249 166 103 139 200 ptg000018l:3290332-3296568 Q4L235 2.95e-50 Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein NRPS998) Homo sapiens (Human) amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; beta-alanine metabolic process [GO:0019482]; fatty acid metabolic process [GO:0006631] GO:0005524; GO:0006631; GO:0016878; GO:0019482; GO:0043041 18662 FUN_024201 249 166 103 139 200 ptg000018l:3290332-3296568 Q4L235 1.48e-39 Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein NRPS998) Homo sapiens (Human) amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; beta-alanine metabolic process [GO:0019482]; fatty acid metabolic process [GO:0006631] GO:0005524; GO:0006631; GO:0016878; GO:0019482; GO:0043041 18663 FUN_024201 249 166 103 139 200 ptg000018l:3290332-3296568 Q4L235 1.64e-24 Beta-alanine-activating enzyme (EC 6.2.1.-) (Acyl-CoA synthetase family member 4) (Protein NRPS998) Homo sapiens (Human) amino acid activation for nonribosomal peptide biosynthetic process [GO:0043041]; beta-alanine metabolic process [GO:0019482]; fatty acid metabolic process [GO:0006631] GO:0005524; GO:0006631; GO:0016878; GO:0019482; GO:0043041 18664 FUN_024202 50 47 37 4 79 NA NA NA NA NA NA NA 18665 FUN_024203 40 0 2 10 59 NA NA NA NA NA NA NA 18666 FUN_024204 21 0 37 0 11 NA NA NA NA NA NA NA 18667 FUN_024205 42 64 99 18 12 NA NA NA NA NA NA NA 18668 FUN_024206 760 1618 748 508 1490 ptg000018l:3331702-3347356 P21328 4.06e-30 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 18669 FUN_024207 35 107 102 207 168 NA NA NA NA NA NA NA 18670 FUN_044288 0 7 0 0 9 NA NA NA NA NA NA NA 18671 FUN_044287 13 23 36 21 21 NA NA NA NA NA NA NA 18672 FUN_044284 68 8 84 15 29 NA NA NA NA NA NA NA 18673 FUN_044282 6 6 28 50 16 NA NA NA NA NA NA NA 18674 FUN_044283 54 24 140 129 63 NA NA NA NA NA NA NA 18675 FUN_044280 0 0 1 0 12 NA NA NA NA NA NA NA 18676 FUN_028204 9 2 0 20 126 NA NA NA NA NA NA NA 18677 FUN_028205 0 0 0 113 0 NA NA NA NA NA NA NA 18678 FUN_028206 0 303 0 0 0 NA NA NA NA NA NA NA 18679 FUN_010774 335 308 132 252 180 NA NA NA NA NA NA NA 18680 FUN_028200 2010 1709 1132 1974 2233 ptg000021l:16810807-16815447 Q4R7L3 6.21e-96 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein catabolic process [GO:0030163] GO:0005524; GO:0005654; GO:0005829; GO:0016887; GO:0022624; GO:0030163; GO:0036402 18681 FUN_028200 2010 1709 1132 1974 2233 ptg000021l:16810807-16815447 Q4R7L3 6.21e-96 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein catabolic process [GO:0030163] GO:0005524; GO:0005654; GO:0005829; GO:0016887; GO:0022624; GO:0030163; GO:0036402 18682 FUN_028200 2010 1709 1132 1974 2233 ptg000021l:16810807-16815447 Q4R7L3 2.69e-33 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein catabolic process [GO:0030163] GO:0005524; GO:0005654; GO:0005829; GO:0016887; GO:0022624; GO:0030163; GO:0036402 18683 FUN_028200 2010 1709 1132 1974 2233 ptg000021l:16810807-16815447 Q4R7L3 1.02e-24 26S proteasome regulatory subunit 6B (26S proteasome AAA-ATPase subunit RPT3) (Proteasome 26S subunit ATPase 4) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein catabolic process [GO:0030163] GO:0005524; GO:0005654; GO:0005829; GO:0016887; GO:0022624; GO:0030163; GO:0036402 18684 FUN_028201 79 530 0 35 0 NA NA NA NA NA NA NA 18685 FUN_028202 49 28 17 29 19 NA NA NA NA NA NA NA 18686 FUN_028203 0 0 0 56 44 NA NA NA NA NA NA NA 18687 FUN_034219 791 908 688 1236 1283 NA NA NA NA NA NA NA 18688 FUN_023968 1150 3081 1661 2027 1208 NA NA NA NA NA NA NA 18689 FUN_023969 2104 1543 1317 1311 1349 NA NA NA NA NA NA NA 18690 FUN_031608 4189 2747 1794 3997 3115 NA NA NA NA NA NA NA 18691 FUN_031609 0 7 7 18 0 NA NA NA NA NA NA NA 18692 FUN_031606 615 501 229 874 920 ptg000023l:23441948-23450171 Q810J8 1.08e-62 Zinc finger FYVE domain-containing protein 1 Mus musculus (Mouse) cellular response to starvation [GO:0009267]; lipid droplet formation [GO:0140042]; macroautophagy [GO:0016236] GO:0000407; GO:0005545; GO:0005547; GO:0005739; GO:0005776; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005811; GO:0009267; GO:0016020; GO:0016236; GO:0032266; GO:0043325; GO:0044233; GO:0046872; GO:0048471; GO:0097629; GO:0140042; GO:1990462 18693 FUN_031606 615 501 229 874 920 ptg000023l:23441948-23450171 Q810J8 1.67e-27 Zinc finger FYVE domain-containing protein 1 Mus musculus (Mouse) cellular response to starvation [GO:0009267]; lipid droplet formation [GO:0140042]; macroautophagy [GO:0016236] GO:0000407; GO:0005545; GO:0005547; GO:0005739; GO:0005776; GO:0005783; GO:0005789; GO:0005794; GO:0005795; GO:0005811; GO:0009267; GO:0016020; GO:0016236; GO:0032266; GO:0043325; GO:0044233; GO:0046872; GO:0048471; GO:0097629; GO:0140042; GO:1990462 18694 FUN_031607 603 506 295 508 558 NA NA NA NA NA NA NA 18695 FUN_031604 77 19 14 37 4 NA NA NA NA NA NA NA 18696 FUN_023967 62 0 31 0 279 NA NA NA NA NA NA NA 18697 FUN_023960 2188 1137 1433 2136 1591 NA NA NA NA NA NA NA 18698 FUN_023961 119 21 24 133 24 ptg000018l:611569-616661 P16092 1.28e-73 Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331) Mus musculus (Mouse) angiogenesis [GO:0001525]; auditory receptor cell development [GO:0060117]; blood vessel morphogenesis [GO:0048514]; brain development [GO:0007420]; branching involved in salivary gland morphogenesis [GO:0060445]; calcium ion homeostasis [GO:0055074]; cardiac muscle cell proliferation [GO:0060038]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cementum mineralization [GO:0071529]; central nervous system neuron development [GO:0021954]; chondrocyte differentiation [GO:0002062]; diphosphate metabolic process [GO:0071344]; ear development [GO:0043583]; embryonic limb morphogenesis [GO:0030326]; epithelial to mesenchymal transition [GO:0001837]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development [GO:0035607]; gene expression [GO:0010467]; generation of neurons [GO:0048699]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; lung development [GO:0030324]; lung-associated mesenchyme development [GO:0060484]; mesenchymal cell differentiation [GO:0048762]; mesenchymal cell proliferation [GO:0010463]; midbrain development [GO:0030901]; middle ear morphogenesis [GO:0042474]; motogenic signaling involved in postnatal olfactory bulb interneuron migration [GO:0021837]; negative regulation of fibroblast growth factor production [GO:0090272]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuron projection development [GO:0031175]; orbitofrontal cortex development [GO:0021769]; organ induction [GO:0001759]; outer ear morphogenesis [GO:0042473]; paraxial mesoderm development [GO:0048339]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of endothelial cell chemotaxis to fibroblast growth factor [GO:2000546]; positive regulation of fibroblast migration [GO:0010763]; positive regulation of hepatic stellate cell activation [GO:2000491]; positive regulation of inflammatory response [GO:0050729]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway [GO:0090080]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of mitotic cell cycle DNA replication [GO:1903465]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of neuron projection development [GO:0010976]; positive regulation of parathyroid hormone secretion [GO:2000830]; positive regulation of phospholipase C activity [GO:0010863]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial cell proliferation [GO:1905564]; protein autophosphorylation [GO:0046777]; regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [GO:0060665]; regulation of cell population proliferation [GO:0042127]; regulation of epithelial cell proliferation [GO:0050678]; regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001239]; regulation of gene expression [GO:0010468]; regulation of lateral mesodermal cell fate specification [GO:0048378]; regulation of phosphate transport [GO:0010966]; regulation of phosphorus metabolic process [GO:0051174]; regulation of sensory perception of pain [GO:0051930]; regulation of stem cell proliferation [GO:0072091]; response to sodium phosphate [GO:1904383]; salivary gland morphogenesis [GO:0007435]; sensory perception of sound [GO:0007605]; stem cell differentiation [GO:0048863]; stem cell population maintenance [GO:0019827]; stem cell proliferation [GO:0072089]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureteric bud development [GO:0001657]; vasculogenesis involved in coronary vascular morphogenesis [GO:0060979]; ventricular zone neuroblast division [GO:0021847]; vitamin D3 metabolic process [GO:0070640] GO:0000122; GO:0001525; GO:0001657; GO:0001701; GO:0001759; GO:0001837; GO:0002053; GO:0002062; GO:0004713; GO:0004714; GO:0005007; GO:0005102; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007169; GO:0007420; GO:0007435; GO:0007605; GO:0008201; GO:0008283; GO:0008284; GO:0008543; GO:0010463; GO:0010467; GO:0010468; GO:0010629; GO:0010763; GO:0010863; GO:0010966; GO:0010976; GO:0017134; GO:0018108; GO:0019827; GO:0021769; GO:0021837; GO:0021847; GO:0021954; GO:0030324; GO:0030326; GO:0030901; GO:0031175; GO:0031410; GO:0033674; GO:0035607; GO:0042127; GO:0042169; GO:0042472; GO:0042473; GO:0042474; GO:0042802; GO:0042803; GO:0043235; GO:0043406; GO:0043410; GO:0043536; GO:0043583; GO:0044877; GO:0045597; GO:0045666; GO:0045668; GO:0045787; GO:0045944; GO:0046777; GO:0048339; GO:0048378; GO:0048469; GO:0048471; GO:0048514; GO:0048699; GO:0048762; GO:0048863; GO:0050678; GO:0050729; GO:0050839; GO:0051174; GO:0051897; GO:0051930; GO:0055074; GO:0060038; GO:0060045; GO:0060117; GO:0060445; GO:0060484; GO:0060665; GO:0060979; GO:0070640; GO:0071344; GO:0071529; GO:0072089; GO:0072091; GO:0090080; GO:0090272; GO:0090722; GO:1903465; GO:1904383; GO:1905564; GO:2000491; GO:2000546; GO:2000648; GO:2000830; GO:2001239 18699 FUN_031600 0 24 2 3 43 NA NA NA NA NA NA NA 18700 FUN_031601 0 0 0 18 0 NA NA NA NA NA NA NA 18701 FUN_039470 0 0 0 0 66 ptg000030l:451062-455677 P14381 2.07e-116 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 18702 FUN_039473 0 0 37 0 0 NA NA NA NA NA NA NA 18703 FUN_024367 1145 531 485 914 845 NA NA NA NA NA NA NA 18704 FUN_024366 1355 827 735 1542 1225 ptg000018l:5446648-5454958 Q6P1S4 4.59e-58 Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) arginyl-tRNA aminoacylation [GO:0006420] GO:0004814; GO:0005524; GO:0005829; GO:0006420; GO:0017101 18705 FUN_024366 1355 827 735 1542 1225 ptg000018l:5446648-5454958 Q6P1S4 1.61e-25 Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) arginyl-tRNA aminoacylation [GO:0006420] GO:0004814; GO:0005524; GO:0005829; GO:0006420; GO:0017101 18706 FUN_035746 1233 612 218 2269 1069 ptg000025l:11245037-11247908 Q8R151 3.41e-63 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 18707 FUN_035745 0 0 0 27 29 NA NA NA NA NA NA NA 18708 FUN_035744 1760 1039 1430 2685 1421 ptg000025l:11226229-11235672 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 18709 FUN_035744 1760 1039 1430 2685 1421 ptg000025l:11226229-11235672 Q9P2E3 1.01e-65 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 18710 FUN_035743 669 324 180 507 232 NA NA NA NA NA NA NA 18711 FUN_026875 3 0 0 0 7 NA NA NA NA NA NA NA 18712 FUN_026877 0 0 0 0 6 NA NA NA NA NA NA NA 18713 FUN_035740 20 0 10 5 10 NA NA NA NA NA NA NA 18714 FUN_026871 0 0 0 0 26 NA NA NA NA NA NA NA 18715 FUN_026870 0 0 15 0 10 NA NA NA NA NA NA NA 18716 FUN_026872 214 22 10 33 10 NA NA NA NA NA NA NA 18717 FUN_039299 98 4 15 13 45 NA NA NA NA NA NA NA 18718 FUN_039291 82 126 21 49 127 NA NA NA NA NA NA NA 18719 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 2.45e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18720 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 8.13e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18721 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 3.12e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18722 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 4.03e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18723 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 1.42e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18724 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 1.25e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18725 FUN_039290 708 268 54 237 168 ptg000028l:359028-369770 Q96AY4 9.34e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18726 FUN_039293 11951 14475 8984 12716 9464 ptg000028l:389925-395432 P55070 5.34e-42 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) Lactarius deterrimus (False saffron milkcap) glycolytic process [GO:0006096] GO:0004365; GO:0005737; GO:0006096; GO:0051287 18727 FUN_039292 969 490 315 467 679 ptg000028l:378597-387701 P21127 4.82e-23 Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1) Homo sapiens (Human) apoptotic process [GO:0006915]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of centrosome cycle [GO:0046605]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; regulation of mRNA processing [GO:0050684]; regulation of RNA splicing [GO:0043484] GO:0000278; GO:0000307; GO:0001558; GO:0003723; GO:0004672; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0006915; GO:0007346; GO:0042981; GO:0043484; GO:0046605; GO:0050684; GO:0051726; GO:0106310 18728 FUN_039295 286 275 259 250 341 NA NA NA NA NA NA NA 18729 FUN_039294 341 188 346 207 198 ptg000028l:397166-414279 P49916 4.45e-21 DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3) Homo sapiens (Human) base-excision repair, DNA ligation [GO:0006288]; base-excision repair, gap-filling [GO:0006287]; cell cycle [GO:0007049]; cell division [GO:0051301]; DNA biosynthetic process [GO:0071897]; DNA ligation [GO:0006266]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; double-strand break repair via homologous recombination [GO:0000724]; lagging strand elongation [GO:0006273]; mitochondrial DNA repair [GO:0043504]; mitochondrion organization [GO:0007005]; negative regulation of mitochondrial DNA replication [GO:0090298] GO:0000724; GO:0003677; GO:0003909; GO:0003910; GO:0005524; GO:0005634; GO:0005654; GO:0005739; GO:0006266; GO:0006273; GO:0006287; GO:0006288; GO:0006302; GO:0007005; GO:0007049; GO:0008270; GO:0043504; GO:0051301; GO:0070421; GO:0071897; GO:0090298; GO:0097681 18730 FUN_039296 376 211 185 212 165 NA NA NA NA NA NA NA 18731 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 2.72e-40 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18732 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 4.53e-39 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18733 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 5.63e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18734 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 1.21e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18735 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 1.53e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18736 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 2.18e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18737 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 4.92e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18738 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 6.16e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18739 FUN_037529 198 175 158 165 320 ptg000026l:11419019-11432162 Q03650 4.64e-35 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 18740 FUN_032407 6 0 0 14 0 ptg000023l:31629433-31632136 Q6DIV6 1.32e-41 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 18741 FUN_037525 6 1788 271 1298 655 NA NA NA NA NA NA NA 18742 FUN_037527 1993 1155 715 2096 918 NA NA NA NA NA NA NA 18743 FUN_037526 453 1280 446 674 1003 NA NA NA NA NA NA NA 18744 FUN_037521 22 0 0 39 27 NA NA NA NA NA NA NA 18745 FUN_037520 7 0 0 0 0 NA NA NA NA NA NA NA 18746 FUN_037523 7 0 0 0 0 NA NA NA NA NA NA NA 18747 FUN_037522 16 23 45 0 122 NA NA NA NA NA NA NA 18748 FUN_037297 703 505 43 316 266 ptg000026l:8351785-8355949 B8V7S0 3.44e-44 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 18749 FUN_037296 668 198 146 115 55 ptg000026l:8345023-8350570 B8V7S0 1.38e-41 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 18750 FUN_037295 614 207 507 1310 1264 NA NA NA NA NA NA NA 18751 FUN_037294 1160 283 395 1452 1414 ptg000026l:8252506-8327723 B8V7S0 3.13e-38 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 18752 FUN_037293 2594 956 2364 536 567 NA NA NA NA NA NA NA 18753 FUN_037292 146 123 125 306 95 NA NA NA NA NA NA NA 18754 FUN_037291 27789 40042 16917 23487 18319 ptg000026l:8176722-8180943 P79324 4.69e-47 60S ribosomal protein L15 Sus scrofa (Pig) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0022625 18755 FUN_037290 679 612 436 551 494 ptg000026l:8174590-8176056 A7SWD3 9.7e-105 Glucose-induced degradation protein 8 homolog Nematostella vectensis (Starlet sea anemone) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005737; GO:0016055; GO:0043161 18756 FUN_037299 247 134 162 100 269 NA NA NA NA NA NA NA 18757 FUN_037298 2451 2069 1497 2744 2113 ptg000026l:8367216-8404479 Q8IVV2 3.73e-30 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 18758 FUN_037298 2451 2069 1497 2744 2113 ptg000026l:8367216-8404479 Q8IVV2 6.99e-22 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 18759 FUN_037298 2451 2069 1497 2744 2113 ptg000026l:8367216-8404479 Q8IVV2 1.36e-21 Lipoxygenase homology domain-containing protein 1 Homo sapiens (Human) sensory perception of sound [GO:0007605] GO:0007605; GO:0032420 18760 FUN_001267 2287 2253 1178 2422 1928 ntLink_6:10545940-10548680 P30536 3.8e-21 Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) Homo sapiens (Human) adrenal gland development [GO:0030325]; aging [GO:0007568]; anion transport [GO:0006820]; behavioral response to pain [GO:0048266]; C21-steroid hormone biosynthetic process [GO:0006700]; cellular hypotonic response [GO:0071476]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to zinc ion [GO:0071294]; chloride transport [GO:0006821]; cholesterol homeostasis [GO:0042632]; contact inhibition [GO:0060242]; glial cell migration [GO:0008347]; heme biosynthetic process [GO:0006783]; maintenance of protein location in mitochondrion [GO:0072656]; negative regulation of ATP metabolic process [GO:1903579]; negative regulation of autophagy of mitochondrion [GO:1903147]; negative regulation of corticosterone secretion [GO:2000853]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of tumor necrosis factor production [GO:0032720]; peripheral nervous system axon regeneration [GO:0014012]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mitochondrial depolarization [GO:0051901]; positive regulation of necrotic cell death [GO:0010940]; positive regulation of reactive oxygen species metabolic process [GO:2000379]; protein targeting to mitochondrion [GO:0006626]; regulation of cell population proliferation [GO:0042127]; regulation of cholesterol transport [GO:0032374]; regulation of steroid biosynthetic process [GO:0050810]; response to acetylcholine [GO:1905144]; response to manganese ion [GO:0010042]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; response to vitamin B1 [GO:0010266]; response to xenobiotic stimulus [GO:0009410]; steroid metabolic process [GO:0008202] GO:0005497; GO:0005739; GO:0005741; GO:0005783; GO:0005829; GO:0006626; GO:0006700; GO:0006783; GO:0006820; GO:0006821; GO:0007568; GO:0008202; GO:0008347; GO:0008503; GO:0009410; GO:0010042; GO:0010266; GO:0010940; GO:0014012; GO:0015485; GO:0016020; GO:0030325; GO:0031397; GO:0032374; GO:0032570; GO:0032720; GO:0033574; GO:0042127; GO:0042632; GO:0043065; GO:0043231; GO:0044325; GO:0045019; GO:0048266; GO:0050810; GO:0051901; GO:0051928; GO:0060242; GO:0060252; GO:0060253; GO:0070062; GO:0071222; GO:0071294; GO:0071476; GO:0072656; GO:0120020; GO:1903147; GO:1903579; GO:1905144; GO:2000379; GO:2000853 18761 FUN_001266 11 2 1 1 0 NA NA NA NA NA NA NA 18762 FUN_001265 7 0 4 1 0 NA NA NA NA NA NA NA 18763 FUN_001264 3067 3080 1329 1958 1413 NA NA NA NA NA NA NA 18764 FUN_001262 3 42 56 126 112 NA NA NA NA NA NA NA 18765 FUN_001261 16 195 0 130 194 NA NA NA NA NA NA NA 18766 FUN_001269 7459 2680 4219 2703 1945 NA NA NA NA NA NA NA 18767 FUN_001268 3252 1380 1494 855 663 NA NA NA NA NA NA NA 18768 FUN_014583 47 33 0 41 212 NA NA NA NA NA NA NA 18769 FUN_011799 54 11 7 4 0 NA NA NA NA NA NA NA 18770 FUN_033998 873 417 508 762 798 ptg000024l:3513381-3540232 Q0P4M4 3.4e-21 Cytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein side chain deglutamylation [GO:0035610]; proteolysis [GO:0006508] GO:0004181; GO:0005814; GO:0005829; GO:0006508; GO:0008270; GO:0035610; GO:0036064 18771 FUN_033999 41396 26229 19513 31595 27179 NA NA NA NA NA NA NA 18772 FUN_033990 136 45 54 76 112 NA NA NA NA NA NA NA 18773 FUN_033992 156 101 54 82 336 NA NA NA NA NA NA NA 18774 FUN_033993 47 8 27 53 19 NA NA NA NA NA NA NA 18775 FUN_033994 42 37 21 55 2 NA NA NA NA NA NA NA 18776 FUN_033995 0 3 7 14 1 NA NA NA NA NA NA NA 18777 FUN_033996 199 44 56 130 83 NA NA NA NA NA NA NA 18778 FUN_033997 55 42 26 8 25 NA NA NA NA NA NA NA 18779 FUN_004224 1449 1448 627 837 1273 NA NA NA NA NA NA NA 18780 FUN_004225 1675 1100 542 1057 744 ntLink_8:20914437-20916078 Q8BHI9 1.2e-78 Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0042149; GO:0106310 18781 FUN_004225 1675 1100 542 1057 744 ntLink_8:20914437-20916078 Q8BHI9 3.45e-62 Serine/threonine-protein kinase NIM1 (EC 2.7.11.1) (NIM1 serine/threonine-protein kinase) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0035556; GO:0042149; GO:0106310 18782 FUN_004226 684 465 271 413 324 NA NA NA NA NA NA NA 18783 FUN_004227 1053 891 709 1226 945 NA NA NA NA NA NA NA 18784 FUN_004222 1170 459 397 663 591 NA NA NA NA NA NA NA 18785 FUN_004223 126 89 73 92 143 ntLink_8:20898918-20899775 Q5RDC7 1.96e-27 RWD domain-containing protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235] GO:0005634; GO:0005737; GO:0032088; GO:0033235; GO:1902073 18786 FUN_004223 126 89 73 92 143 ntLink_8:20898918-20899775 Q5RDC7 1.96e-27 RWD domain-containing protein 3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of hypoxia-inducible factor-1alpha signaling pathway [GO:1902073]; positive regulation of protein sumoylation [GO:0033235] GO:0005634; GO:0005737; GO:0032088; GO:0033235; GO:1902073 18787 FUN_004228 4624 2176 2066 3221 2511 NA NA NA NA NA NA NA 18788 FUN_004229 1085 1722 946 1495 1388 NA NA NA NA NA NA NA 18789 FUN_016759 40 4 35 89 203 ptg000011l:7071673-7088349 S8FIE4 1.76e-42 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 18790 FUN_034176 214 229 103 298 275 NA NA NA NA NA NA NA 18791 FUN_034175 10 0 24 0 11 NA NA NA NA NA NA NA 18792 FUN_034174 643 1082 509 751 769 NA NA NA NA NA NA NA 18793 FUN_034173 2749 2158 2583 2477 3459 ptg000024l:5680393-5686984 Q6UPE0 4.88e-71 Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1) Rattus norvegicus (Rat) glycine betaine biosynthetic process from choline [GO:0019285] GO:0005743; GO:0008812; GO:0016491; GO:0019285; GO:0050660 18794 FUN_034173 2749 2158 2583 2477 3459 ptg000024l:5680393-5686984 Q6UPE0 1.59e-30 Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1) Rattus norvegicus (Rat) glycine betaine biosynthetic process from choline [GO:0019285] GO:0005743; GO:0008812; GO:0016491; GO:0019285; GO:0050660 18795 FUN_034173 2749 2158 2583 2477 3459 ptg000024l:5680393-5686984 Q6UPE0 4.84e-22 Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1) Rattus norvegicus (Rat) glycine betaine biosynthetic process from choline [GO:0019285] GO:0005743; GO:0008812; GO:0016491; GO:0019285; GO:0050660 18796 FUN_034173 2749 2158 2583 2477 3459 ptg000024l:5680393-5686984 Q6UPE0 1.09e-21 Choline dehydrogenase, mitochondrial (CDH) (CHD) (EC 1.1.99.1) Rattus norvegicus (Rat) glycine betaine biosynthetic process from choline [GO:0019285] GO:0005743; GO:0008812; GO:0016491; GO:0019285; GO:0050660 18797 FUN_034172 99 60 105 54 215 NA NA NA NA NA NA NA 18798 FUN_034171 310 372 243 311 240 NA NA NA NA NA NA NA 18799 FUN_034170 21 59 38 71 74 NA NA NA NA NA NA NA 18800 FUN_034179 682 127 159 467 564 NA NA NA NA NA NA NA 18801 FUN_034178 45 0 59 105 48 NA NA NA NA NA NA NA 18802 FUN_013983 11 97 3 5 80 NA NA NA NA NA NA NA 18803 FUN_013985 10 6 41 2 13 NA NA NA NA NA NA NA 18804 FUN_013984 118 0 34 0 0 NA NA NA NA NA NA NA 18805 FUN_019142 12 0 17 1 48 NA NA NA NA NA NA NA 18806 FUN_019141 1937 930 863 1644 901 NA NA NA NA NA NA NA 18807 FUN_019146 0 0 0 9 0 NA NA NA NA NA NA NA 18808 FUN_027981 336 439 272 267 322 ptg000021l:14172856-14179645 P20749 1.52e-22 B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3) Homo sapiens (Human) antimicrobial humoral response [GO:0019730]; cellular response to DNA damage stimulus [GO:0006974]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; humoral immune response mediated by circulating immunoglobulin [GO:0002455]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [GO:0042771]; marginal zone B cell differentiation [GO:0002315]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; negative regulation of T cell apoptotic process [GO:0070233]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of translation [GO:0045727]; positive regulation of type II interferon production [GO:0032729]; protein import into nucleus [GO:0006606]; regulation of apoptotic process [GO:0042981]; regulation of DNA binding [GO:0051101]; regulation of NIK/NF-kappaB signaling [GO:1901222]; response to UV-C [GO:0010225]; response to virus [GO:0009615]; spleen development [GO:0048536]; T cell apoptotic process [GO:0070231]; T-helper 1 type immune response [GO:0042088]; T-helper 2 cell differentiation [GO:0045064] GO:0002268; GO:0002315; GO:0002455; GO:0002467; GO:0003713; GO:0003714; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006606; GO:0006974; GO:0007249; GO:0009615; GO:0010225; GO:0019730; GO:0030198; GO:0030330; GO:0030496; GO:0030674; GO:0032088; GO:0032717; GO:0032720; GO:0032729; GO:0032733; GO:0032991; GO:0032996; GO:0033257; GO:0042088; GO:0042742; GO:0042771; GO:0042826; GO:0042832; GO:0042981; GO:0043066; GO:0043231; GO:0045064; GO:0045727; GO:0045892; GO:0045893; GO:0045944; GO:0046426; GO:0048471; GO:0048536; GO:0051101; GO:0070231; GO:0070233; GO:0140297; GO:1901222 18809 FUN_014456 3243 1483 1760 2934 2223 NA NA NA NA NA NA NA 18810 FUN_019148 168 139 23 2 92 NA NA NA NA NA NA NA 18811 FUN_014457 54 20 0 11 23 NA NA NA NA NA NA NA 18812 FUN_014455 1486 948 925 1004 1221 ptg000009l:345464-347596 Q6ICL3 2.06e-35 Transport and Golgi organization protein 2 homolog Homo sapiens (Human) Golgi organization [GO:0007030]; protein secretion [GO:0009306] GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0007030; GO:0009306 18813 FUN_014458 2171 1896 1286 2023 1579 NA NA NA NA NA NA NA 18814 FUN_013487 190 0 4 22 192 NA NA NA NA NA NA NA 18815 FUN_044130 51 164 65 134 371 NA NA NA NA NA NA NA 18816 FUN_030217 3 0 3 0 8 ptg000023l:10385602-10386365 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18817 FUN_030215 3 0 3 0 7 ptg000023l:10381550-10382313 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18818 FUN_030213 3 0 3 0 9 ptg000023l:10377498-10378261 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18819 FUN_030210 1 0 3 0 7 ptg000023l:10373447-10374210 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18820 FUN_030211 26 1 34 5 167 ptg000023l:10374474-10374786 Q6LAF1 1.14e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18821 FUN_030219 2 0 2 0 13 ptg000023l:10393706-10394469 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18822 FUN_044132 60 173 80 174 430 NA NA NA NA NA NA NA 18823 FUN_005808 4161 2990 2005 3821 3134 ptg000001l:4140337-4173729 F6Z5C0 2.02e-59 Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0006511; GO:0007179; GO:0016579; GO:0030509; GO:0035520; GO:0035616; GO:0060389 18824 FUN_005808 4161 2990 2005 3821 3134 ptg000001l:4140337-4173729 F6Z5C0 7.52e-21 Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) BMP signaling pathway [GO:0030509]; histone H2B conserved C-terminal lysine deubiquitination [GO:0035616]; monoubiquitinated protein deubiquitination [GO:0035520]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; protein deubiquitination [GO:0016579]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005737; GO:0006511; GO:0007179; GO:0016579; GO:0030509; GO:0035520; GO:0035616; GO:0060389 18825 FUN_044134 50 166 79 140 368 NA NA NA NA NA NA NA 18826 FUN_011428 26 20 1 0 6 NA NA NA NA NA NA NA 18827 FUN_043109 152 186 109 68 365 ptg000047l:4238341-4239844 O73853 8.32e-100 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 18828 FUN_040440 19 6 35 14 0 NA NA NA NA NA NA NA 18829 FUN_040441 440 158 90 297 234 NA NA NA NA NA NA NA 18830 FUN_040442 1811 1950 1045 1616 1144 NA NA NA NA NA NA NA 18831 FUN_037889 4 6 1 1 3 NA NA NA NA NA NA NA 18832 FUN_040444 20656 19029 7608 18776 15597 ptg000031l:8519034-8528414 Q5R546 3.69e-54 ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0001937; GO:0005524; GO:0005753; GO:0005886; GO:0006629; GO:0008180; GO:0042288; GO:0042776; GO:0043532; GO:0043536; GO:0045261; GO:0046933 18833 FUN_040444 20656 19029 7608 18776 15597 ptg000031l:8519034-8528414 Q5R546 8.39e-25 ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0001937; GO:0005524; GO:0005753; GO:0005886; GO:0006629; GO:0008180; GO:0042288; GO:0042776; GO:0043532; GO:0043536; GO:0045261; GO:0046933 18834 FUN_040444 20656 19029 7608 18776 15597 ptg000031l:8519034-8528414 Q5R546 3.28e-24 ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0001937; GO:0005524; GO:0005753; GO:0005886; GO:0006629; GO:0008180; GO:0042288; GO:0042776; GO:0043532; GO:0043536; GO:0045261; GO:0046933 18835 FUN_040444 20656 19029 7608 18776 15597 ptg000031l:8519034-8528414 Q5R546 2.87e-23 ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; negative regulation of endothelial cell proliferation [GO:0001937]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; proton motive force-driven mitochondrial ATP synthesis [GO:0042776] GO:0001937; GO:0005524; GO:0005753; GO:0005886; GO:0006629; GO:0008180; GO:0042288; GO:0042776; GO:0043532; GO:0043536; GO:0045261; GO:0046933 18836 FUN_040445 628 1239 1087 620 475 NA NA NA NA NA NA NA 18837 FUN_040446 0 33 25 0 7 NA NA NA NA NA NA NA 18838 FUN_040447 71 65 59 0 288 NA NA NA NA NA NA NA 18839 FUN_040448 268 291 154 63 123 NA NA NA NA NA NA NA 18840 FUN_037883 2 2 5 1 39 NA NA NA NA NA NA NA 18841 FUN_037880 70 783 196 309 382 NA NA NA NA NA NA NA 18842 FUN_037881 37 134 27 81 226 NA NA NA NA NA NA NA 18843 FUN_037886 86 176 160 173 480 NA NA NA NA NA NA NA 18844 FUN_037887 4 4 13 2 117 NA NA NA NA NA NA NA 18845 FUN_037884 35 158 34 97 258 NA NA NA NA NA NA NA 18846 FUN_037885 0 127 0 0 0 NA NA NA NA NA NA NA 18847 FUN_011424 0 0 0 0 29 NA NA NA NA NA NA NA 18848 FUN_043204 131 40 29 68 0 NA NA NA NA NA NA NA 18849 FUN_043203 550 401 192 370 482 NA NA NA NA NA NA NA 18850 FUN_043106 1110 480 459 749 1199 NA NA NA NA NA NA NA 18851 FUN_007000 315 70 131 170 308 ptg000001l:19190602-19203660 O95239 3.35e-44 Chromosome-associated kinesin KIF4A (Chromokinesin-A) Homo sapiens (Human) anterograde axonal transport [GO:0008089]; mitotic cytokinesis [GO:0000281]; mitotic spindle midzone assembly [GO:0051256]; mitotic spindle organization [GO:0007052]; organelle organization [GO:0006996]; spindle elongation [GO:0051231] GO:0000281; GO:0003677; GO:0003777; GO:0005524; GO:0005654; GO:0005694; GO:0005737; GO:0005829; GO:0005875; GO:0005876; GO:0006996; GO:0007052; GO:0008017; GO:0008089; GO:0016020; GO:0016363; GO:0030496; GO:0046872; GO:0051231; GO:0051256; GO:0051536; GO:1904115 18852 FUN_043107 392 256 277 573 394 NA NA NA NA NA NA NA 18853 FUN_007003 79 405 156 183 50 NA NA NA NA NA NA NA 18854 FUN_011420 7 0 1 10 49 NA NA NA NA NA NA NA 18855 FUN_043101 757 568 534 1185 950 ptg000047l:4140626-4151051 Q8R4K8 4.86e-179 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 18856 FUN_043101 757 568 534 1185 950 ptg000047l:4140626-4151051 Q8R4K8 9.63e-31 Pappalysin-1 (EC 3.4.24.79) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase) (Pregnancy-associated plasma protein A) (PAPP-A) Mus musculus (Mouse) cell surface receptor signaling pathway [GO:0007166]; female pregnancy [GO:0007565]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508]; response to dexamethasone [GO:0071548]; response to follicle-stimulating hormone [GO:0032354] GO:0004175; GO:0004222; GO:0005576; GO:0005615; GO:0006508; GO:0007166; GO:0007565; GO:0008237; GO:0030163; GO:0032354; GO:0046872; GO:0071548 18857 FUN_011422 0 0 0 262 0 NA NA NA NA NA NA NA 18858 FUN_043103 28 0 18 6 13 NA NA NA NA NA NA NA 18859 FUN_007009 4 6 14 8 87 NA NA NA NA NA NA NA 18860 FUN_005895 411 399 442 424 448 NA NA NA NA NA NA NA 18861 FUN_005896 1090 886 774 807 626 ptg000001l:5403675-5418721 Q9NBX4 1.61e-30 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 18862 FUN_043208 92 58 46 76 55 NA NA NA NA NA NA NA 18863 FUN_032104 4526 2842 2452 4602 4542 ptg000023l:28856943-28883445 Q8IWV8 7.33e-37 E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) Homo sapiens (Human) cellular response to leucine [GO:0071233]; heterochromatin formation [GO:0031507]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transposition [GO:0010529]; protein ubiquitination [GO:0016567]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] GO:0000151; GO:0000785; GO:0005634; GO:0005737; GO:0005829; GO:0007131; GO:0007140; GO:0007141; GO:0007283; GO:0008270; GO:0010529; GO:0016567; GO:0031507; GO:0032007; GO:0033522; GO:0061630; GO:0070728; GO:0071233; GO:0071596 18864 FUN_032104 4526 2842 2452 4602 4542 ptg000023l:28856943-28883445 Q8IWV8 1.3e-26 E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II) Homo sapiens (Human) cellular response to leucine [GO:0071233]; heterochromatin formation [GO:0031507]; histone H2A ubiquitination [GO:0033522]; male meiosis I [GO:0007141]; male meiotic nuclear division [GO:0007140]; negative regulation of TOR signaling [GO:0032007]; negative regulation of transposition [GO:0010529]; protein ubiquitination [GO:0016567]; reciprocal meiotic recombination [GO:0007131]; spermatogenesis [GO:0007283]; ubiquitin-dependent protein catabolic process via the N-end rule pathway [GO:0071596] GO:0000151; GO:0000785; GO:0005634; GO:0005737; GO:0005829; GO:0007131; GO:0007140; GO:0007141; GO:0007283; GO:0008270; GO:0010529; GO:0016567; GO:0031507; GO:0032007; GO:0033522; GO:0061630; GO:0070728; GO:0071233; GO:0071596 18865 FUN_032105 672 213 140 381 481 ptg000023l:28894304-28899971 P39428 8.6e-32 TNF receptor-associated factor 1 Mus musculus (Mouse) apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005737; GO:0006915; GO:0008270; GO:0009898; GO:0031625; GO:0031996; GO:0033209; GO:0042802; GO:0043122; GO:0046330; GO:0051092; GO:0070534; GO:2001236 18866 FUN_032106 4988 3809 2708 6264 4184 ptg000023l:28901732-28912845 Q5R637 2.77e-34 T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005524; GO:0005815; GO:0005832; GO:0005929; GO:0016887; GO:0042470; GO:0051082; GO:0140662 18867 FUN_032106 4988 3809 2708 6264 4184 ptg000023l:28901732-28912845 Q5R637 4.59e-26 T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005524; GO:0005815; GO:0005832; GO:0005929; GO:0016887; GO:0042470; GO:0051082; GO:0140662 18868 FUN_032107 3283 2606 2102 1630 2806 NA NA NA NA NA NA NA 18869 FUN_032100 0 0 0 35 46 NA NA NA NA NA NA NA 18870 FUN_032101 2918 2701 1209 1269 1172 ptg000023l:28843723-28845593 Q05B60 6.41e-26 Uridine diphosphate glucose pyrophosphatase NUDT14 (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14) Bos taurus (Bovine) nucleoside phosphate metabolic process [GO:0006753]; ribose phosphate metabolic process [GO:0019693] GO:0005737; GO:0006753; GO:0008768; GO:0019693; GO:0042802; GO:0046872; GO:0047631 18871 FUN_032102 581 1768 466 588 612 NA NA NA NA NA NA NA 18872 FUN_032103 241 181 128 236 313 NA NA NA NA NA NA NA 18873 FUN_032108 1393 1728 719 1077 679 ptg000023l:28915238-28919028 Q99P55 1.9e-36 Sphingosine-1-phosphate phosphatase 1 (SPPase1) (Spp1) (EC 3.1.3.-) (Sphingosine-1-phosphatase 1) Rattus norvegicus (Rat) ER to Golgi ceramide transport [GO:0035621]; extrinsic apoptotic signaling pathway [GO:0097191]; intrinsic apoptotic signaling pathway [GO:0097193]; phospholipid dephosphorylation [GO:0046839]; regulation of epidermis development [GO:0045682]; regulation of keratinocyte differentiation [GO:0045616]; sphinganine-1-phosphate metabolic process [GO:0006668]; sphingolipid metabolic process [GO:0006665]; sphingosine metabolic process [GO:0006670] GO:0005783; GO:0005789; GO:0005886; GO:0006665; GO:0006668; GO:0006670; GO:0016020; GO:0035621; GO:0042392; GO:0045616; GO:0045682; GO:0046839; GO:0070780; GO:0097191; GO:0097193 18874 FUN_032109 2452 2159 1093 825 878 NA NA NA NA NA NA NA 18875 FUN_043930 0 0 0 0 6 NA NA NA NA NA NA NA 18876 FUN_043932 4 0 0 1 14 NA NA NA NA NA NA NA 18877 FUN_043935 4 8 11 0 101 NA NA NA NA NA NA NA 18878 FUN_043934 63 229 85 212 534 NA NA NA NA NA NA NA 18879 FUN_043937 58 188 71 155 417 NA NA NA NA NA NA NA 18880 FUN_043936 10 15 18 23 64 NA NA NA NA NA NA NA 18881 FUN_043939 5 0 16 2 110 NA NA NA NA NA NA NA 18882 FUN_043938 0 0 1 1 6 NA NA NA NA NA NA NA 18883 FUN_008057 239 88 237 338 182 NA NA NA NA NA NA NA 18884 FUN_007708 4423 4919 2656 4248 3836 ptg000002l:3528910-3580882 Q6ZQ93 1.41e-25 Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) Mus musculus (Mouse) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016055; GO:0016579; GO:0071108; GO:0090263 18885 FUN_002950 80 0 20 8 59 NA NA NA NA NA NA NA 18886 FUN_007700 120 127 6 62 59 NA NA NA NA NA NA NA 18887 FUN_007701 812 454 315 475 311 NA NA NA NA NA NA NA 18888 FUN_007707 68 55 73 99 53 ptg000002l:3512268-3522305 P97363 1.69e-21 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Mus musculus (Mouse) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; lipophagy [GO:0061724]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005739; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:0061724; GO:1904504 18889 FUN_002956 0 0 0 0 69 NA NA NA NA NA NA NA 18890 FUN_007705 22 0 119 158 79 ptg000002l:3440809-3494796 P10978 0 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 18891 FUN_007705 22 0 119 158 79 ptg000002l:3440809-3494796 P10978 0 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 18892 FUN_008419 1090 25 855 24 7 NA NA NA NA NA NA NA 18893 FUN_008418 29231 24301 15525 23866 14021 ptg000002l:11337446-11345535 Q5BL41 8.72e-49 Actin-related protein 2 (Actin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861; GO:0042995; GO:0045944; GO:1905168 18894 FUN_008418 29231 24301 15525 23866 14021 ptg000002l:11337446-11345535 Q5BL41 2.76e-43 Actin-related protein 2 (Actin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861; GO:0042995; GO:0045944; GO:1905168 18895 FUN_008418 29231 24301 15525 23866 14021 ptg000002l:11337446-11345535 Q5BL41 2.76e-43 Actin-related protein 2 (Actin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861; GO:0042995; GO:0045944; GO:1905168 18896 FUN_008418 29231 24301 15525 23866 14021 ptg000002l:11337446-11345535 Q5BL41 2.76e-43 Actin-related protein 2 (Actin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861; GO:0042995; GO:0045944; GO:1905168 18897 FUN_008418 29231 24301 15525 23866 14021 ptg000002l:11337446-11345535 Q5BL41 1.29e-22 Actin-related protein 2 (Actin-like protein 2) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Arp2/3 complex-mediated actin nucleation [GO:0034314]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0003779; GO:0005524; GO:0005634; GO:0005737; GO:0005885; GO:0034314; GO:0035861; GO:0042995; GO:0045944; GO:1905168 18898 FUN_008417 911 486 441 843 677 ptg000002l:11329284-11334764 Q8TBZ3 5.4e-117 WD repeat-containing protein 20 (Protein DMR) Homo sapiens (Human) NA GO:0005654 18899 FUN_008417 911 486 441 843 677 ptg000002l:11329284-11334764 Q8TBZ3 5.05e-23 WD repeat-containing protein 20 (Protein DMR) Homo sapiens (Human) NA GO:0005654 18900 FUN_008417 911 486 441 843 677 ptg000002l:11329284-11334764 Q8TBZ3 4.39e-22 WD repeat-containing protein 20 (Protein DMR) Homo sapiens (Human) NA GO:0005654 18901 FUN_008416 1065 532 550 941 1093 NA NA NA NA NA NA NA 18902 FUN_008415 1515 676 907 1550 1748 NA NA NA NA NA NA NA 18903 FUN_008414 291 116 160 416 249 ptg000002l:11268500-11278454 P12804 5.4e-35 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 18904 FUN_008412 220 124 135 289 87 NA NA NA NA NA NA NA 18905 FUN_008411 505 301 329 573 461 ptg000002l:11229246-11240685 P12804 4.18e-33 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 18906 FUN_008410 0 0 0 0 8 NA NA NA NA NA NA NA 18907 FUN_041478 1480 964 698 1110 1267 NA NA NA NA NA NA NA 18908 FUN_013959 0 0 0 0 23 NA NA NA NA NA NA NA 18909 FUN_013957 51 41 15 70 87 NA NA NA NA NA NA NA 18910 FUN_005630 0 0 4 0 13 NA NA NA NA NA NA NA 18911 FUN_041473 200 2445 1842 647 1953 NA NA NA NA NA NA NA 18912 FUN_013950 226 11 0 267 308 NA NA NA NA NA NA NA 18913 FUN_013951 20 35 17 11 46 NA NA NA NA NA NA NA 18914 FUN_008055 10129 12876 13054 12500 7109 NA NA NA NA NA NA NA 18915 FUN_042024 8144 8466 4981 7443 7395 NA NA NA NA NA NA NA 18916 FUN_000610 201 214 38 189 94 NA NA NA NA NA NA NA 18917 FUN_033769 1917 1881 1096 1347 1225 NA NA NA NA NA NA NA 18918 FUN_033768 999 940 685 583 389 NA NA NA NA NA NA NA 18919 FUN_033767 406 339 358 480 268 ptg000024l:1171084-1174177 Q1AE95 3.89e-47 Putative transmembrane protein 183BP (Transmembrane protein 183B pseudogene) Homo sapiens (Human) regulation of protein stability [GO:0031647] GO:0016020; GO:0019005; GO:0031647 18920 FUN_033766 0 14 23 0 10 NA NA NA NA NA NA NA 18921 FUN_033765 694 311 545 530 603 ptg000024l:1149673-1160360 E9Q236 2.38e-92 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 18922 FUN_033765 694 311 545 530 603 ptg000024l:1149673-1160360 E9Q236 2.14e-67 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 18923 FUN_033764 1394 583 578 1211 571 ptg000024l:1135532-1147670 Q8INF0 1.09e-68 Soluble guanylate cyclase 88E (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0003924; GO:0004383; GO:0005525; GO:0008074; GO:0019825; GO:0019826; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0042803; GO:0046872; GO:0046982; GO:0070025; GO:0070026; GO:0070482 18924 FUN_033763 2621 1730 1625 3649 2957 ptg000024l:1118578-1130765 Q6BDS2 4.82e-24 Bridge-like lipid transfer protein family member 3A (ICBP90-binding protein 1) (UHRF1-binding protein 1) (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) Homo sapiens (Human) NA GO:0005770; GO:0042802; GO:0042826 18925 FUN_033762 3705 3849 2648 2201 2948 NA NA NA NA NA NA NA 18926 FUN_033761 4688 3482 2706 1373 3095 NA NA NA NA NA NA NA 18927 FUN_033760 768 437 390 995 1009 NA NA NA NA NA NA NA 18928 FUN_003779 0 0 38 18 0 NA NA NA NA NA NA NA 18929 FUN_003778 3 13 295 223 0 ntLink_8:15294100-15308834 Q9P215 3.83e-91 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 18930 FUN_012333 8217 4861 4356 7664 5337 ptg000008l:7991753-7993556 B4HF64 5.95e-46 Forkhead box protein O Drosophila sechellia (Fruit fly) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; glucose homeostasis [GO:0042593]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of insulin receptor signaling pathway [GO:0046627]; regulation of DNA-templated transcription [GO:0006355]; regulation of lipid metabolic process [GO:0019216] GO:0003700; GO:0005634; GO:0005737; GO:0006355; GO:0007049; GO:0008285; GO:0019216; GO:0030154; GO:0030308; GO:0042593; GO:0043565; GO:0046627 18931 FUN_012334 2732 1602 4591 3976 3945 ptg000008l:8004470-8038315 Q61493 6.67e-30 DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] GO:0000166; GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005730; GO:0006260; GO:0006281; GO:0016035; GO:0042276; GO:0046872; GO:0051539 18932 FUN_012334 2732 1602 4591 3976 3945 ptg000008l:8004470-8038315 Q61493 3.97e-27 DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] GO:0000166; GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005730; GO:0006260; GO:0006281; GO:0016035; GO:0042276; GO:0046872; GO:0051539 18933 FUN_012334 2732 1602 4591 3976 3945 ptg000008l:8004470-8038315 Q61493 8.64e-26 DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] GO:0000166; GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005730; GO:0006260; GO:0006281; GO:0016035; GO:0042276; GO:0046872; GO:0051539 18934 FUN_012334 2732 1602 4591 3976 3945 ptg000008l:8004470-8038315 Q61493 1.31e-22 DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (Seizure-related protein 4) Mus musculus (Mouse) DNA repair [GO:0006281]; DNA replication [GO:0006260]; double-strand break repair via homologous recombination [GO:0000724]; error-prone translesion synthesis [GO:0042276] GO:0000166; GO:0000724; GO:0003677; GO:0003887; GO:0005634; GO:0005730; GO:0006260; GO:0006281; GO:0016035; GO:0042276; GO:0046872; GO:0051539 18935 FUN_012336 23 0 14 6 21 ptg000008l:8044952-8046039 Q8CGS6 1.68e-27 DNA polymerase theta (EC 2.7.7.7) (Chromosome aberrations occurring spontaneously protein 1) (DNA polymerase eta) Mus musculus (Mouse) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0003682; GO:0003887; GO:0005524; GO:0005654; GO:0005694; GO:0005794; GO:0005829; GO:0006261; GO:0006281; GO:0006284; GO:0006302; GO:0006974; GO:0016446; GO:0017116; GO:0042802; GO:0051260; GO:0051575; GO:0097681; GO:2000042 18936 FUN_012339 693 565 462 793 759 NA NA NA NA NA NA NA 18937 FUN_012338 3073 6487 4361 8515 5197 NA NA NA NA NA NA NA 18938 FUN_010791 1221 1035 201 1006 486 ptg000007l:2815663-2847850 A0A1Y9G8H0 1.78e-32 NA NA NA NA 18939 FUN_010791 1221 1035 201 1006 486 ptg000007l:2815663-2847850 A0A1Y9G8H0 3.36e-22 NA NA NA NA 18940 FUN_010790 0 0 0 4 8 NA NA NA NA NA NA NA 18941 FUN_028264 4 0 0 0 78 NA NA NA NA NA NA NA 18942 FUN_010792 2009 2982 4695 2332 1831 ptg000007l:2852533-2886054 B3A0Q8 7.22e-27 Peroxidase-like protein 3 Lottia gigantea (Giant owl limpet) response to oxidative stress [GO:0006979] GO:0004601; GO:0005576; GO:0006979; GO:0020037 18943 FUN_010792 2009 2982 4695 2332 1831 ptg000007l:2852533-2886054 B3A0Q8 9.2e-24 Peroxidase-like protein 3 Lottia gigantea (Giant owl limpet) response to oxidative stress [GO:0006979] GO:0004601; GO:0005576; GO:0006979; GO:0020037 18944 FUN_028262 499 837 239 392 596 ptg000021l:17393435-17402552 Q6DE87 2.38e-21 Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1) (xChk1) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint signaling [GO:0000077]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]; signal transduction in response to DNA damage [GO:0042770]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000077; GO:0000785; GO:0000794; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0006974; GO:0007095; GO:0010569; GO:0010767; GO:0018107; GO:0035402; GO:0042770; GO:0045815; GO:0045839; GO:0046602; GO:0106310; GO:2000615 18945 FUN_028262 499 837 239 392 596 ptg000021l:17393435-17402552 Q6DE87 2.38e-21 Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Checkpoint kinase-1) (xChk1) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA damage checkpoint signaling [GO:0000077]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of mitotic nuclear division [GO:0045839]; peptidyl-threonine phosphorylation [GO:0018107]; protein phosphorylation [GO:0006468]; regulation of double-strand break repair via homologous recombination [GO:0010569]; regulation of histone H3-K9 acetylation [GO:2000615]; regulation of mitotic centrosome separation [GO:0046602]; regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage [GO:0010767]; signal transduction in response to DNA damage [GO:0042770]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000077; GO:0000785; GO:0000794; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0006974; GO:0007095; GO:0010569; GO:0010767; GO:0018107; GO:0035402; GO:0042770; GO:0045815; GO:0045839; GO:0046602; GO:0106310; GO:2000615 18946 FUN_028263 341 140 142 171 163 ptg000021l:17403654-17408516 P07286 8.16e-28 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase) (Tunicamycin resistance protein 1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) aerobic respiration [GO:0009060]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; protein N-linked glycosylation [GO:0006487] GO:0003975; GO:0005783; GO:0006487; GO:0006488; GO:0009060; GO:0016020; GO:0016757; GO:0043541; GO:0046872 18947 FUN_010797 572 240 261 439 608 NA NA NA NA NA NA NA 18948 FUN_028261 340 5 504 132 0 NA NA NA NA NA NA NA 18949 FUN_010799 2235 1008 1037 2328 2145 NA NA NA NA NA NA NA 18950 FUN_010798 427 191 290 375 159 NA NA NA NA NA NA NA 18951 FUN_028269 541 209 170 300 434 NA NA NA NA NA NA NA 18952 FUN_034238 824 972 715 966 458 NA NA NA NA NA NA NA 18953 FUN_034239 833 375 585 1265 661 NA NA NA NA NA NA NA 18954 FUN_034234 817 432 467 537 206 NA NA NA NA NA NA NA 18955 FUN_034235 25 52 11 80 47 NA NA NA NA NA NA NA 18956 FUN_034236 51 95 111 127 67 NA NA NA NA NA NA NA 18957 FUN_034237 119 43 66 174 82 NA NA NA NA NA NA NA 18958 FUN_034230 3824 2597 1630 3099 2388 ptg000024l:6335140-6354852 P0CT39 7.69e-79 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 18959 FUN_034231 2943 2726 1237 2201 1710 NA NA NA NA NA NA NA 18960 FUN_034232 1421 1274 799 1414 1032 ptg000024l:6367732-6382589 Q7ZXF5 1.51e-24 Fatty acyl-CoA reductase 1 (EC 1.2.1.84) Xenopus laevis (African clawed frog) ether lipid biosynthetic process [GO:0008611]; wax biosynthetic process [GO:0010025] GO:0005778; GO:0008611; GO:0010025; GO:0080019; GO:0102965 18961 FUN_034233 543 346 445 593 411 NA NA NA NA NA NA NA 18962 FUN_043131 1501 1435 1214 1275 876 NA NA NA NA NA NA NA 18963 FUN_030363 7 0 9 0 27 ptg000023l:10701718-10702481 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 18964 FUN_041276 2669 827 342 2003 1328 NA NA NA NA NA NA NA 18965 FUN_014474 3824 3746 3226 5751 6376 ptg000009l:493146-538469 Q61789 1.03e-51 Laminin subunit alpha-3 (Epiligrin subunit alpha) (Kalinin subunit alpha) (Laminin-5 subunit alpha) (Laminin-6 subunit alpha) (Laminin-7 subunit alpha) (Nicein subunit alpha) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; endodermal cell differentiation [GO:0035987]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; morphogenesis of a polarized epithelium [GO:0001738]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; tissue development [GO:0009888] GO:0001738; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005608; GO:0005610; GO:0005783; GO:0005912; GO:0007229; GO:0007411; GO:0009887; GO:0009888; GO:0016477; GO:0030056; GO:0030155; GO:0030334; GO:0031581; GO:0035987; GO:0045995; GO:0062023; GO:0098609 18966 FUN_014474 3824 3746 3226 5751 6376 ptg000009l:493146-538469 Q61789 1.03e-51 Laminin subunit alpha-3 (Epiligrin subunit alpha) (Kalinin subunit alpha) (Laminin-5 subunit alpha) (Laminin-6 subunit alpha) (Laminin-7 subunit alpha) (Nicein subunit alpha) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; endodermal cell differentiation [GO:0035987]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; morphogenesis of a polarized epithelium [GO:0001738]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; tissue development [GO:0009888] GO:0001738; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005608; GO:0005610; GO:0005783; GO:0005912; GO:0007229; GO:0007411; GO:0009887; GO:0009888; GO:0016477; GO:0030056; GO:0030155; GO:0030334; GO:0031581; GO:0035987; GO:0045995; GO:0062023; GO:0098609 18967 FUN_014474 3824 3746 3226 5751 6376 ptg000009l:493146-538469 Q61789 1.03e-51 Laminin subunit alpha-3 (Epiligrin subunit alpha) (Kalinin subunit alpha) (Laminin-5 subunit alpha) (Laminin-6 subunit alpha) (Laminin-7 subunit alpha) (Nicein subunit alpha) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; endodermal cell differentiation [GO:0035987]; hemidesmosome assembly [GO:0031581]; integrin-mediated signaling pathway [GO:0007229]; morphogenesis of a polarized epithelium [GO:0001738]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; tissue development [GO:0009888] GO:0001738; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005608; GO:0005610; GO:0005783; GO:0005912; GO:0007229; GO:0007411; GO:0009887; GO:0009888; GO:0016477; GO:0030056; GO:0030155; GO:0030334; GO:0031581; GO:0035987; GO:0045995; GO:0062023; GO:0098609 18968 FUN_014475 9893 7357 4608 11095 6539 ptg000009l:540017-546286 Q501Q9 1.09e-27 Mitogen-activated protein kinase 15 (EC 2.7.11.24) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017] GO:0004707; GO:0005524; GO:0005737; GO:0005911; GO:0005929; GO:0006468; GO:0035253; GO:0036064; GO:0106310; GO:1902017 18969 FUN_014476 41 23 32 9 45 NA NA NA NA NA NA NA 18970 FUN_014477 1164 716 457 706 1441 ptg000009l:550204-562961 Q0VGM9 1.98e-25 Regulator of telomere elongation helicase 1 (EC 3.6.4.12) Mus musculus (Mouse) DNA duplex unwinding [GO:0032508]; DNA repair [GO:0006281]; mitotic telomere maintenance via semi-conservative replication [GO:1902990]; negative regulation of DNA recombination [GO:0045910]; negative regulation of t-circle formation [GO:1904430]; negative regulation of telomere maintenance in response to DNA damage [GO:1904506]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomere lengthening [GO:1904358]; positive regulation of telomeric loop disassembly [GO:1904535]; regulation of double-strand break repair via homologous recombination [GO:0010569]; replication fork processing [GO:0031297]; strand displacement [GO:0000732]; telomere maintenance [GO:0000723]; telomere maintenance in response to DNA damage [GO:0043247]; telomeric D-loop disassembly [GO:0061820]; telomeric loop disassembly [GO:0090657] GO:0000723; GO:0000732; GO:0000781; GO:0003677; GO:0003678; GO:0004386; GO:0005524; GO:0005634; GO:0006281; GO:0010569; GO:0016887; GO:0031297; GO:0032206; GO:0032508; GO:0043247; GO:0045910; GO:0046872; GO:0051539; GO:0061820; GO:0070182; GO:0090657; GO:1902990; GO:1904355; GO:1904358; GO:1904430; GO:1904506; GO:1904535 18971 FUN_014470 0 0 0 23 18 NA NA NA NA NA NA NA 18972 FUN_014471 42 0 20 0 130 NA NA NA NA NA NA NA 18973 FUN_014472 0 0 0 0 13 NA NA NA NA NA NA NA 18974 FUN_014473 1508 949 615 1119 995 NA NA NA NA NA NA NA 18975 FUN_014478 949 633 1268 2020 1059 NA NA NA NA NA NA NA 18976 FUN_014479 0 3 13 9 9 NA NA NA NA NA NA NA 18977 FUN_043166 1029 286 623 1060 842 NA NA NA NA NA NA NA 18978 FUN_043164 483 576 209 498 641 NA NA NA NA NA NA NA 18979 FUN_043162 1030 1482 717 981 563 NA NA NA NA NA NA NA 18980 FUN_043163 0 0 0 251 422 NA NA NA NA NA NA NA 18981 FUN_043160 152 161 119 62 21 NA NA NA NA NA NA NA 18982 FUN_000941 0 11 0 0 15 NA NA NA NA NA NA NA 18983 FUN_000940 0 0 0 29 0 NA NA NA NA NA NA NA 18984 FUN_000943 3002 2021 976 1875 1313 NA NA NA NA NA NA NA 18985 FUN_000945 302 87 220 205 303 NA NA NA NA NA NA NA 18986 FUN_000944 3131 2704 1227 2588 2699 NA NA NA NA NA NA NA 18987 FUN_014788 524 280 366 427 152 NA NA NA NA NA NA NA 18988 FUN_014789 548 390 242 485 330 NA NA NA NA NA NA NA 18989 FUN_014787 5658 2974 2651 4951 4527 NA NA NA NA NA NA NA 18990 FUN_014783 170 51 286 375 517 ptg000009l:3042352-3050974 Q5UQ13 7.38e-30 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 18991 FUN_014783 170 51 286 375 517 ptg000009l:3042352-3050974 Q5UQ13 4.25e-27 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 18992 FUN_014783 170 51 286 375 517 ptg000009l:3042352-3050974 Q5UQ13 1.95e-23 Collagen-like protein 2 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0044423 18993 FUN_014780 8232 6062 10764 8253 8894 NA NA NA NA NA NA NA 18994 FUN_009733 0 0 0 0 27 NA NA NA NA NA NA NA 18995 FUN_009732 61 0 6 65 3 ptg000004l:10915470-10917276 Q96AY4 1.43e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18996 FUN_009732 61 0 6 65 3 ptg000004l:10915470-10917276 Q96AY4 2.69e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 18997 FUN_009737 6 0 28 9 21 NA NA NA NA NA NA NA 18998 FUN_009736 1725 615 948 904 643 ptg000004l:10942826-10958162 G5EBQ8 1.77e-21 Chitin synthase chs-2 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase chs-2) Caenorhabditis elegans cell wall chitin biosynthetic process [GO:0006038]; chitin biosynthetic process [GO:0006031]; positive regulation of nematode larval development [GO:0061063] GO:0004100; GO:0005886; GO:0006031; GO:0006038; GO:0030428; GO:0061063; GO:0071944 18999 FUN_009738 4 0 0 501 0 NA NA NA NA NA NA NA 19000 FUN_029618 22 0 0 0 26 NA NA NA NA NA NA NA 19001 FUN_029619 1 10 7 0 14 NA NA NA NA NA NA NA 19002 FUN_029614 533 405 434 527 320 ptg000023l:3730650-3732819 F6QEU4 3.72e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 19003 FUN_029615 42 0 4 21 9 ptg000023l:3750951-3752735 Q9EQD2 3.28e-29 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 19004 FUN_029616 1460 1631 556 1212 714 NA NA NA NA NA NA NA 19005 FUN_029617 50 50 15 16 49 NA NA NA NA NA NA NA 19006 FUN_029610 50 66 46 100 4 NA NA NA NA NA NA NA 19007 FUN_029611 1179 778 760 1049 305 ptg000023l:3710216-3713007 F6QEU4 1.42e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 19008 FUN_029612 13 6 13 17 36 NA NA NA NA NA NA NA 19009 FUN_029613 248 68 22 139 98 ptg000023l:3722232-3724455 E7FAM5 3.45e-60 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19010 FUN_026509 9 0 17 0 90 NA NA NA NA NA NA NA 19011 FUN_026508 14 0 4 0 34 NA NA NA NA NA NA NA 19012 FUN_023759 3028 1466 1768 3232 2054 NA NA NA NA NA NA NA 19013 FUN_023758 27480 25678 20737 14478 10479 NA NA NA NA NA NA NA 19014 FUN_015784 0 1 0 0 7 NA NA NA NA NA NA NA 19015 FUN_015787 0 0 9 7 41 NA NA NA NA NA NA NA 19016 FUN_015783 122 0 84 45 0 NA NA NA NA NA NA NA 19017 FUN_015782 97 0 6 23 0 NA NA NA NA NA NA NA 19018 FUN_015788 0 0 8 6 0 NA NA NA NA NA NA NA 19019 FUN_015439 93 60 2 27 26 NA NA NA NA NA NA NA 19020 FUN_015438 28 36 52 66 46 NA NA NA NA NA NA NA 19021 FUN_015437 76 73 0 39 32 NA NA NA NA NA NA NA 19022 FUN_015436 2941 2978 1456 2660 1860 NA NA NA NA NA NA NA 19023 FUN_015435 173 125 49 85 157 NA NA NA NA NA NA NA 19024 FUN_015434 41379 34038 20088 41460 28281 ptg000009l:10125666-10128350 P53448 2.85e-121 Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) Carassius auratus (Goldfish) fructose 1,6-bisphosphate metabolic process [GO:0030388]; glycolytic process [GO:0006096] GO:0004332; GO:0006096; GO:0030388 19025 FUN_015433 36079 48125 12124 42838 26712 NA NA NA NA NA NA NA 19026 FUN_015430 21 0 0 0 0 NA NA NA NA NA NA NA 19027 FUN_027047 0 0 0 0 48 NA NA NA NA NA NA NA 19028 FUN_017197 0 5 9 0 116 NA NA NA NA NA NA NA 19029 FUN_027045 22 0 0 0 0 NA NA NA NA NA NA NA 19030 FUN_017195 6 0 0 0 0 NA NA NA NA NA NA NA 19031 FUN_024759 1778 1041 532 98 932 NA NA NA NA NA NA NA 19032 FUN_024909 141 229 145 234 122 NA NA NA NA NA NA NA 19033 FUN_024908 784 598 114 420 615 NA NA NA NA NA NA NA 19034 FUN_024903 25 0 0 22 0 NA NA NA NA NA NA NA 19035 FUN_024902 169 91 81 140 118 ptg000018l:12409963-12411598 Q96DM1 6.72e-68 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 19036 FUN_024901 827 367 335 626 672 ptg000018l:12400998-12406719 O54853 7.2e-39 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 19037 FUN_024907 753 414 285 366 362 NA NA NA NA NA NA NA 19038 FUN_024906 1873 1224 706 1149 595 ptg000018l:12481648-12482876 P48969 1.66e-37 Protein DVR-1 homolog Strongylocentrotus purpuratus (Purple sea urchin) BMP signaling pathway [GO:0030509]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] GO:0005125; GO:0005615; GO:0008083; GO:0010862; GO:0030509; GO:0060395 19039 FUN_024905 97 58 111 215 229 NA NA NA NA NA NA NA 19040 FUN_024904 147 32 0 196 79 ptg000018l:12431999-12439990 P34576 1e-23 Transmembrane cell adhesion receptor mua-3 (Muscle attachment abnormal protein 3) Caenorhabditis elegans cell-matrix adhesion [GO:0007160] GO:0005509; GO:0005518; GO:0005882; GO:0005886; GO:0007160; GO:0019215; GO:0030056 19041 FUN_025368 65702 54611 30396 40045 19983 ptg000019l:1962306-1971707 P79959 1.02e-42 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) (XGbeta1) Xenopus laevis (African clawed frog) signal transduction [GO:0007165] GO:0007165 19042 FUN_025369 12 7 0 30 9 NA NA NA NA NA NA NA 19043 FUN_025360 75 0 112 68 365 NA NA NA NA NA NA NA 19044 FUN_025361 42114 56293 28659 35047 22923 NA NA NA NA NA NA NA 19045 FUN_025362 6061 6118 6936 5590 2436 NA NA NA NA NA NA NA 19046 FUN_025363 17536 8328 6956 14438 8043 ptg000019l:1911254-1923198 B0S5G3 4.41e-24 NA NA NA NA 19047 FUN_025364 1096 1114 645 1211 770 NA NA NA NA NA NA NA 19048 FUN_025365 2741 1542 1445 2547 2126 NA NA NA NA NA NA NA 19049 FUN_025366 499 208 172 227 321 NA NA NA NA NA NA NA 19050 FUN_025367 9486 7333 4756 9146 6459 ptg000019l:1947727-1959194 Q5R6Y1 2.14e-21 Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 1) (Non-neural enolase) (NNE) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) canonical glycolysis [GO:0061621] GO:0000015; GO:0000287; GO:0004634; GO:0005886; GO:0061621 19051 FUN_041279 0 0 0 6 39 NA NA NA NA NA NA NA 19052 FUN_017199 0 0 0 0 7 NA NA NA NA NA NA NA 19053 FUN_043849 9 0 0 0 8 NA NA NA NA NA NA NA 19054 FUN_032704 1294 906 696 1149 803 NA NA NA NA NA NA NA 19055 FUN_019439 0 0 0 13 0 NA NA NA NA NA NA NA 19056 FUN_019438 9 5 14 6 136 NA NA NA NA NA NA NA 19057 FUN_019433 39 18 3 30 16 NA NA NA NA NA NA NA 19058 FUN_019432 41 27 19 87 41 NA NA NA NA NA NA NA 19059 FUN_019430 0 22 0 0 16 NA NA NA NA NA NA NA 19060 FUN_019437 646 579 396 492 459 NA NA NA NA NA NA NA 19061 FUN_019436 1099 469 345 914 1403 NA NA NA NA NA NA NA 19062 FUN_019434 10 4 30 57 18 NA NA NA NA NA NA NA 19063 FUN_038269 4649 4153 2698 3786 3351 NA NA NA NA NA NA NA 19064 FUN_030057 242 161 125 263 116 NA NA NA NA NA NA NA 19065 FUN_030051 2 0 12 4 87 NA NA NA NA NA NA NA 19066 FUN_038263 7 14 7 11 7 NA NA NA NA NA NA NA 19067 FUN_038262 7 0 17 71 68 NA NA NA NA NA NA NA 19068 FUN_038261 0 0 21 70 11 NA NA NA NA NA NA NA 19069 FUN_038260 8 0 11 81 20 NA NA NA NA NA NA NA 19070 FUN_030059 78 64 34 63 40 ptg000023l:8886351-8892311 Q9J569 4.15e-24 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 19071 FUN_038265 2227 2815 1185 1974 1785 NA NA NA NA NA NA NA 19072 FUN_038264 107 58 62 58 61 NA NA NA NA NA NA NA 19073 FUN_001847 6170 2083 1703 5141 2418 ntLink_6:16933821-16948816 Q28001 8.94e-50 Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) Bos taurus (Bovine) alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] GO:0006836; GO:0008021; GO:0015293; GO:0015804; GO:0015816; GO:0015820; GO:0015824; GO:0016020; GO:0030672; GO:0032328; GO:0035725; GO:0042995; GO:0098794 19074 FUN_001846 766 315 277 563 404 ntLink_6:16916632-16927009 Q28001 1.15e-34 Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) Bos taurus (Bovine) alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] GO:0006836; GO:0008021; GO:0015293; GO:0015804; GO:0015816; GO:0015820; GO:0015824; GO:0016020; GO:0030672; GO:0032328; GO:0035725; GO:0042995; GO:0098794 19075 FUN_001845 630 443 232 540 571 ntLink_6:16902771-16913244 Q13395 4.37e-71 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] GO:0003723; GO:0005634; GO:0006357; GO:0016423; GO:0030488 19076 FUN_001845 630 443 232 540 571 ntLink_6:16902771-16913244 Q13395 2.33e-29 Probable methyltransferase TARBP1 (EC 2.1.1.-) (TAR RNA-binding protein 1) (TAR RNA-binding protein of 185 kDa) (TRP-185) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357]; tRNA methylation [GO:0030488] GO:0003723; GO:0005634; GO:0006357; GO:0016423; GO:0030488 19077 FUN_001844 5 14 32 19 61 NA NA NA NA NA NA NA 19078 FUN_001843 2 56 13 62 16 NA NA NA NA NA NA NA 19079 FUN_001842 2056 794 684 1020 612 ntLink_6:16867041-16877271 O70437 9.76e-68 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4) Rattus norvegicus (Rat) adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesendoderm development [GO:0048382]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001822; GO:0001837; GO:0003148; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003279; GO:0003360; GO:0003677; GO:0003682; GO:0003700; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006355; GO:0006357; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0008584; GO:0008585; GO:0009653; GO:0009952; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032991; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042127; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0046881; GO:0048382; GO:0048589; GO:0048663; GO:0048729; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0072133; GO:0072134; GO:0072520; GO:0090575; GO:0140537; GO:1902895; GO:1905305; GO:2000617 19080 FUN_001842 2056 794 684 1020 612 ntLink_6:16867041-16877271 O70437 2.86e-62 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4) Rattus norvegicus (Rat) adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesendoderm development [GO:0048382]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001822; GO:0001837; GO:0003148; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003279; GO:0003360; GO:0003677; GO:0003682; GO:0003700; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006355; GO:0006357; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0008584; GO:0008585; GO:0009653; GO:0009952; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032991; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042127; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0046881; GO:0048382; GO:0048589; GO:0048663; GO:0048729; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0072133; GO:0072134; GO:0072520; GO:0090575; GO:0140537; GO:1902895; GO:1905305; GO:2000617 19081 FUN_001842 2056 794 684 1020 612 ntLink_6:16867041-16877271 O70437 3.18e-26 Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (SMAD family member 4) (SMAD 4) (Smad4) Rattus norvegicus (Rat) adrenal gland development [GO:0030325]; aging [GO:0007568]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; atrioventricular canal development [GO:0036302]; atrioventricular valve formation [GO:0003190]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; brainstem development [GO:0003360]; branching involved in ureteric bud morphogenesis [GO:0001658]; cardiac septum development [GO:0003279]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular iron ion homeostasis [GO:0006879]; cellular response to glucose stimulus [GO:0071333]; developmental growth [GO:0048589]; DNA-templated transcription [GO:0006351]; embryonic digit morphogenesis [GO:0042733]; endocardial cell differentiation [GO:0060956]; endoderm development [GO:0007492]; endothelial cell activation [GO:0042118]; epithelial cell migration [GO:0010631]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; ERK1 and ERK2 cascade [GO:0070371]; female gonad development [GO:0008585]; female gonad morphogenesis [GO:0061040]; formation of anatomical boundary [GO:0048859]; gastrulation [GO:0007369]; gastrulation with mouth forming second [GO:0001702]; in utero embryonic development [GO:0001701]; interleukin-6-mediated signaling pathway [GO:0070102]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; left ventricular cardiac muscle tissue morphogenesis [GO:0003220]; male gonad development [GO:0008584]; mesendoderm development [GO:0048382]; mesoderm development [GO:0007498]; metanephric mesenchyme morphogenesis [GO:0072133]; negative regulation of cardiac muscle hypertrophy [GO:0010614]; negative regulation of cardiac myofibril assembly [GO:1905305]; negative regulation of cell death [GO:0060548]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural crest cell differentiation [GO:0014033]; neuron fate commitment [GO:0048663]; osteoblast differentiation [GO:0001649]; outflow tract septum morphogenesis [GO:0003148]; ovarian follicle development [GO:0001541]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cardiac muscle cell apoptotic process [GO:0010666]; positive regulation of cell proliferation involved in heart valve morphogenesis [GO:0003251]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of follicle-stimulating hormone secretion [GO:0046881]; positive regulation of histone H3-K4 methylation [GO:0051571]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of luteinizing hormone secretion [GO:0033686]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of binding [GO:0051098]; regulation of cell population proliferation [GO:0042127]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair follicle development [GO:0051797]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of transforming growth factor beta2 production [GO:0032909]; response to hypoxia [GO:0001666]; response to transforming growth factor beta [GO:0071559]; sebaceous gland development [GO:0048733]; secondary palate development [GO:0062009]; seminiferous tubule development [GO:0072520]; single fertilization [GO:0007338]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; somite rostral/caudal axis specification [GO:0032525]; spermatogenesis [GO:0007283]; tissue morphogenesis [GO:0048729]; transcription by RNA polymerase II [GO:0006366]; transforming growth factor beta receptor signaling pathway [GO:0007179]; uterus development [GO:0060065]; ventricular septum morphogenesis [GO:0060412]; wound healing [GO:0042060] GO:0000122; GO:0000785; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001223; GO:0001228; GO:0001541; GO:0001649; GO:0001658; GO:0001666; GO:0001701; GO:0001702; GO:0001822; GO:0001837; GO:0003148; GO:0003190; GO:0003198; GO:0003220; GO:0003251; GO:0003279; GO:0003360; GO:0003677; GO:0003682; GO:0003700; GO:0005518; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0005829; GO:0006351; GO:0006355; GO:0006357; GO:0006366; GO:0006879; GO:0007179; GO:0007183; GO:0007283; GO:0007338; GO:0007369; GO:0007411; GO:0007492; GO:0007498; GO:0007568; GO:0008283; GO:0008285; GO:0008584; GO:0008585; GO:0009653; GO:0009952; GO:0010614; GO:0010631; GO:0010666; GO:0010718; GO:0010862; GO:0014033; GO:0017015; GO:0030154; GO:0030308; GO:0030325; GO:0030509; GO:0030511; GO:0030513; GO:0031005; GO:0032444; GO:0032525; GO:0032909; GO:0032991; GO:0033686; GO:0035556; GO:0036302; GO:0042060; GO:0042118; GO:0042127; GO:0042177; GO:0042733; GO:0042802; GO:0042803; GO:0043199; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0046881; GO:0048382; GO:0048589; GO:0048663; GO:0048729; GO:0048733; GO:0048859; GO:0051098; GO:0051571; GO:0051797; GO:0060065; GO:0060391; GO:0060395; GO:0060412; GO:0060548; GO:0060956; GO:0061040; GO:0061629; GO:0062009; GO:0070102; GO:0070371; GO:0070373; GO:0070411; GO:0070412; GO:0071141; GO:0071144; GO:0071333; GO:0071559; GO:0072133; GO:0072134; GO:0072520; GO:0090575; GO:0140537; GO:1902895; GO:1905305; GO:2000617 19082 FUN_001841 1482 1319 1228 1596 1445 ntLink_6:16822168-16862887 P21328 1.72e-27 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19083 FUN_001840 3503 2407 979 1423 2424 NA NA NA NA NA NA NA 19084 FUN_001849 0 0 0 2 6 NA NA NA NA NA NA NA 19085 FUN_001848 558 285 143 504 391 NA NA NA NA NA NA NA 19086 FUN_024019 2196 1015 1449 2322 2233 NA NA NA NA NA NA NA 19087 FUN_024018 1938 1265 1332 1856 1720 ptg000018l:1275941-1278515 Q96T37 1.59e-71 RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; dosage compensation by inactivation of X chromosome [GO:0009048]; negative regulation of myeloid cell differentiation [GO:0045638]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of megakaryocyte differentiation [GO:0045652]; RNA methylation [GO:0001510]; spleen development [GO:0048536]; thrombopoietin-mediated signaling pathway [GO:0038163]; ventricular septum morphogenesis [GO:0060412] GO:0000381; GO:0001510; GO:0001569; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0007221; GO:0009048; GO:0016607; GO:0031965; GO:0036396; GO:0038163; GO:0045638; GO:0045652; GO:0048536; GO:0060412; GO:0060674 19088 FUN_024018 1938 1265 1332 1856 1720 ptg000018l:1275941-1278515 Q96T37 6.39e-41 RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15) Homo sapiens (Human) branching involved in blood vessel morphogenesis [GO:0001569]; dosage compensation by inactivation of X chromosome [GO:0009048]; negative regulation of myeloid cell differentiation [GO:0045638]; placenta blood vessel development [GO:0060674]; positive regulation of transcription of Notch receptor target [GO:0007221]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of megakaryocyte differentiation [GO:0045652]; RNA methylation [GO:0001510]; spleen development [GO:0048536]; thrombopoietin-mediated signaling pathway [GO:0038163]; ventricular septum morphogenesis [GO:0060412] GO:0000381; GO:0001510; GO:0001569; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0007221; GO:0009048; GO:0016607; GO:0031965; GO:0036396; GO:0038163; GO:0045638; GO:0045652; GO:0048536; GO:0060412; GO:0060674 19089 FUN_024011 1445 1074 724 977 1097 NA NA NA NA NA NA NA 19090 FUN_024010 2501 1513 933 1285 673 NA NA NA NA NA NA NA 19091 FUN_024012 5 0 7 0 7 NA NA NA NA NA NA NA 19092 FUN_024015 1451 1370 1264 2663 2054 NA NA NA NA NA NA NA 19093 FUN_024017 1388 557 349 890 1053 NA NA NA NA NA NA NA 19094 FUN_024016 747 609 534 591 694 NA NA NA NA NA NA NA 19095 FUN_038198 13 37 10 65 61 NA NA NA NA NA NA NA 19096 FUN_038197 42 105 0 56 94 NA NA NA NA NA NA NA 19097 FUN_038196 93 71 97 334 209 NA NA NA NA NA NA NA 19098 FUN_038190 89 0 323 541 642 NA NA NA NA NA NA NA 19099 FUN_038192 137 56 210 161 85 NA NA NA NA NA NA NA 19100 FUN_027667 2 13 0 21 16 NA NA NA NA NA NA NA 19101 FUN_027666 590 61 25 0 22 NA NA NA NA NA NA NA 19102 FUN_027665 0 22 0 0 0 NA NA NA NA NA NA NA 19103 FUN_021999 189 157 190 193 170 NA NA NA NA NA NA NA 19104 FUN_021992 0 0 0 35 0 NA NA NA NA NA NA NA 19105 FUN_015419 0 185 0 0 157 NA NA NA NA NA NA NA 19106 FUN_015418 339 5271 1586 755 7299 NA NA NA NA NA NA NA 19107 FUN_012612 1066 1819 772 468 590 NA NA NA NA NA NA NA 19108 FUN_012613 179 56 229 218 249 NA NA NA NA NA NA NA 19109 FUN_027594 0 6 0 0 0 NA NA NA NA NA NA NA 19110 FUN_027591 0 17 0 0 0 NA NA NA NA NA NA NA 19111 FUN_027590 31 53 26 171 67 NA NA NA NA NA NA NA 19112 FUN_010117 4 14 7 0 235 NA NA NA NA NA NA NA 19113 FUN_017225 16 0 1 17 4 NA NA NA NA NA NA NA 19114 FUN_036049 147 40 9 44 25 NA NA NA NA NA NA NA 19115 FUN_036048 29 16 0 55 44 NA NA NA NA NA NA NA 19116 FUN_031019 0 0 0 0 57 NA NA NA NA NA NA NA 19117 FUN_031018 0 0 21 0 3 NA NA NA NA NA NA NA 19118 FUN_036045 61 0 0 0 16 NA NA NA NA NA NA NA 19119 FUN_031016 0 0 0 388 212 NA NA NA NA NA NA NA 19120 FUN_031015 0 0 0 9 0 NA NA NA NA NA NA NA 19121 FUN_036040 98 89 74 103 238 NA NA NA NA NA NA NA 19122 FUN_036043 691 723 480 496 575 NA NA NA NA NA NA NA 19123 FUN_037313 715 663 303 451 341 ptg000026l:8599770-8600490 Q32PP9 1.11e-24 Transcription factor Sox-14 Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hypothalamus development [GO:0021854]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0021854; GO:0030154 19124 FUN_037310 7079 5110 2663 6186 2688 NA NA NA NA NA NA NA 19125 FUN_037311 247 136 91 143 57 NA NA NA NA NA NA NA 19126 FUN_037316 1204 713 570 2721 780 NA NA NA NA NA NA NA 19127 FUN_037317 817 1558 1086 1103 431 NA NA NA NA NA NA NA 19128 FUN_037315 342 96 24 136 178 NA NA NA NA NA NA NA 19129 FUN_037318 34 7 0 16 11 ptg000026l:8668582-8669699 P17124 2.44e-23 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Canis lupus familiaris (Dog) (Canis familiaris) chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0030425; GO:0030594; GO:0045202; GO:0045907 19130 FUN_008227 0 0 0 16 59 ptg000002l:9481602-9485520 Q8AXN9 9.18e-36 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Cynops pyrrhogaster (Japanese fire-bellied newt) (Molge pyrrhogaster) response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; visual perception [GO:0007601]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0005789; GO:0005886; GO:0007601; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0046872; GO:0050896; GO:0052884; GO:0052885; GO:1901612; GO:1901827 19131 FUN_008228 40 20 41 192 87 NA NA NA NA NA NA NA 19132 FUN_006018 1955 1145 1195 1448 2070 NA NA NA NA NA NA NA 19133 FUN_006645 1503 1908 651 854 1149 NA NA NA NA NA NA NA 19134 FUN_006015 700 633 210 210 194 NA NA NA NA NA NA NA 19135 FUN_006017 6 14 8 10 13 NA NA NA NA NA NA NA 19136 FUN_006016 2570 1104 1202 2154 1488 NA NA NA NA NA NA NA 19137 FUN_006011 271 330 137 362 520 NA NA NA NA NA NA NA 19138 FUN_006010 62 142 222 153 164 NA NA NA NA NA NA NA 19139 FUN_006947 0 0 0 0 48 NA NA NA NA NA NA NA 19140 FUN_016428 2238 1265 862 1655 1514 NA NA NA NA NA NA NA 19141 FUN_006944 1141 550 646 514 1126 NA NA NA NA NA NA NA 19142 FUN_016427 142 94 117 133 64 NA NA NA NA NA NA NA 19143 FUN_003801 0 0 0 0 31 NA NA NA NA NA NA NA 19144 FUN_016426 386 328 104 190 192 ptg000011l:2912538-2912979 O73755 1.05e-24 Gremlin-1 Gallus gallus (Chicken) animal organ morphogenesis [GO:0009887]; cardiac muscle cell differentiation [GO:0055007]; cardiac muscle cell myoblast differentiation [GO:0060379]; cell migration involved in sprouting angiogenesis [GO:0002042]; cell morphogenesis [GO:0000902]; cell-cell signaling [GO:0007267]; collagen fibril organization [GO:0030199]; determination of dorsal identity [GO:0048263]; embryonic limb morphogenesis [GO:0030326]; limb development [GO:0060173]; mesenchymal to epithelial transition involved in metanephros morphogenesis [GO:0003337]; negative regulation of apoptotic process [GO:0043066]; negative regulation of bone mineralization involved in bone maturation [GO:1900158]; negative regulation of bone remodeling [GO:0046851]; negative regulation of bone trabecula formation [GO:1900155]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of osteoblast proliferation [GO:0033689]; negative regulation of osteoclast proliferation [GO:0090291]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; positive regulation of angiogenesis [GO:0045766]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor internalization [GO:0002092]; positive regulation of signaling receptor activity [GO:2000273]; positive regulation of telomerase activity [GO:0051973]; positive regulation of transcription by RNA polymerase II [GO:0045944]; proximal/distal pattern formation [GO:0009954]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of focal adhesion assembly [GO:0051893]; sequestering of BMP from receptor via BMP binding [GO:0038098]; ureteric bud formation [GO:0060676] GO:0000902; GO:0002042; GO:0002092; GO:0003337; GO:0005125; GO:0005615; GO:0007267; GO:0008284; GO:0009887; GO:0009954; GO:0009986; GO:0010717; GO:0030199; GO:0030297; GO:0030326; GO:0032331; GO:0033689; GO:0036122; GO:0038098; GO:0042803; GO:0043066; GO:0043184; GO:0045668; GO:0045766; GO:0045892; GO:0045944; GO:0046851; GO:0048018; GO:0048263; GO:0051092; GO:0051893; GO:0051973; GO:0055007; GO:0060173; GO:0060379; GO:0060394; GO:0060676; GO:0061098; GO:0090090; GO:0090190; GO:0090291; GO:1900086; GO:1900155; GO:1900158; GO:1901224; GO:2000273 19145 FUN_004852 1457 1254 942 1741 1209 ntLink_8:27865587-27869508 P70473 5.11e-27 Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-arylpropionyl-CoA epimerase) (2-methylacyl-CoA racemase) Rattus norvegicus (Rat) bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631] GO:0005737; GO:0005739; GO:0005777; GO:0006631; GO:0006699; GO:0008111; GO:0008206 19146 FUN_004852 1457 1254 942 1741 1209 ntLink_8:27865587-27869508 P70473 3.45e-26 Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-arylpropionyl-CoA epimerase) (2-methylacyl-CoA racemase) Rattus norvegicus (Rat) bile acid biosynthetic process [GO:0006699]; bile acid metabolic process [GO:0008206]; fatty acid metabolic process [GO:0006631] GO:0005737; GO:0005739; GO:0005777; GO:0006631; GO:0006699; GO:0008111; GO:0008206 19147 FUN_003803 1 0 0 0 15 NA NA NA NA NA NA NA 19148 FUN_004857 667 158 229 558 455 NA NA NA NA NA NA NA 19149 FUN_004855 317 137 176 163 252 ntLink_8:27888324-27891449 Q8BNU0 1.26e-26 Armadillo repeat-containing protein 6 Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244] GO:0002244; GO:0005829 19150 FUN_004854 411 228 267 180 172 NA NA NA NA NA NA NA 19151 FUN_005434 0 0 0 53 0 NA NA NA NA NA NA NA 19152 FUN_001542 31 6 5 104 125 NA NA NA NA NA NA NA 19153 FUN_001546 5466 4353 2152 3628 3030 NA NA NA NA NA NA NA 19154 FUN_001545 66390 19305 6312 28429 39088 NA NA NA NA NA NA NA 19155 FUN_001548 1366 772 509 276 803 NA NA NA NA NA NA NA 19156 FUN_001549 13672 18226 5833 12161 9045 NA NA NA NA NA NA NA 19157 FUN_004526 4 13 4 0 6 NA NA NA NA NA NA NA 19158 FUN_004525 2077 1381 1031 1556 1253 NA NA NA NA NA NA NA 19159 FUN_004735 60114 47391 27460 48690 33566 ntLink_8:26343359-26343770 Q6P823 5.47e-85 Histone H3.3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19160 FUN_004523 633 563 297 685 608 NA NA NA NA NA NA NA 19161 FUN_004522 356 164 215 286 292 NA NA NA NA NA NA NA 19162 FUN_004521 321 129 153 337 248 NA NA NA NA NA NA NA 19163 FUN_003500 0 0 3 9 58 NA NA NA NA NA NA NA 19164 FUN_004529 9 45 72 64 66 NA NA NA NA NA NA NA 19165 FUN_007874 1635 1387 986 2177 984 NA NA NA NA NA NA NA 19166 FUN_007875 0 7 0 7 0 NA NA NA NA NA NA NA 19167 FUN_007876 306 253 35 0 144 NA NA NA NA NA NA NA 19168 FUN_007877 209 49 0 22 7 NA NA NA NA NA NA NA 19169 FUN_007870 1444 395 546 1017 969 ptg000002l:5612955-5615640 Q8C1A3 2.97e-135 Methionine synthase reductase (MSR) (EC 1.16.1.8) (Aquacobalamin reductase) (AqCbl reductase) Mus musculus (Mouse) cobalamin metabolic process [GO:0009235]; DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; protein stabilization [GO:0050821]; S-adenosylmethionine cycle [GO:0033353] GO:0003958; GO:0005654; GO:0005829; GO:0006306; GO:0009086; GO:0009235; GO:0010181; GO:0016491; GO:0016723; GO:0030586; GO:0033353; GO:0043418; GO:0045111; GO:0046655; GO:0050660; GO:0050667; GO:0050821; GO:0070402; GO:0071949; GO:1904042 19170 FUN_007870 1444 395 546 1017 969 ptg000002l:5612955-5615640 Q8C1A3 7.9e-48 Methionine synthase reductase (MSR) (EC 1.16.1.8) (Aquacobalamin reductase) (AqCbl reductase) Mus musculus (Mouse) cobalamin metabolic process [GO:0009235]; DNA methylation [GO:0006306]; folic acid metabolic process [GO:0046655]; homocysteine catabolic process [GO:0043418]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; negative regulation of cystathionine beta-synthase activity [GO:1904042]; protein stabilization [GO:0050821]; S-adenosylmethionine cycle [GO:0033353] GO:0003958; GO:0005654; GO:0005829; GO:0006306; GO:0009086; GO:0009235; GO:0010181; GO:0016491; GO:0016723; GO:0030586; GO:0033353; GO:0043418; GO:0045111; GO:0046655; GO:0050660; GO:0050667; GO:0050821; GO:0070402; GO:0071949; GO:1904042 19171 FUN_007871 1204 1095 600 1250 830 NA NA NA NA NA NA NA 19172 FUN_007872 137 302 192 448 132 NA NA NA NA NA NA NA 19173 FUN_007873 1051 1393 1187 2132 962 NA NA NA NA NA NA NA 19174 FUN_023850 43 0 23 0 46 ptg000017l:12023857-12026302 Q9U7D0 6.25e-47 Histone H4 Mastigamoeba balamuthi (Phreatamoeba balamuthi) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19175 FUN_004731 287 206 27 336 460 NA NA NA NA NA NA NA 19176 FUN_007878 16 0 0 41 0 NA NA NA NA NA NA NA 19177 FUN_007879 45 34 33 115 85 NA NA NA NA NA NA NA 19178 FUN_023852 3 0 16 0 71 ptg000017l:12030152-12034984 P84239 1.94e-81 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19179 FUN_023853 72 1 100 6 314 ptg000017l:12035149-12035461 Q6LAF1 2.64e-53 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19180 FUN_001094 170 158 58 76 151 NA NA NA NA NA NA NA 19181 FUN_001095 86 80 74 38 40 NA NA NA NA NA NA NA 19182 FUN_001096 142 558 177 428 261 NA NA NA NA NA NA NA 19183 FUN_001097 274 79 54 37 30 NA NA NA NA NA NA NA 19184 FUN_001091 2 23 17 24 14 ntLink_6:8506602-8514985 P21329 6.42e-39 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila funebris (Fruit fly) NA GO:0003964 19185 FUN_001092 19 4 14 26 28 NA NA NA NA NA NA NA 19186 FUN_001093 0 19 7 34 53 NA NA NA NA NA NA NA 19187 FUN_033565 41 19 24 0 61 NA NA NA NA NA NA NA 19188 FUN_033567 0 23 0 14 0 NA NA NA NA NA NA NA 19189 FUN_033566 11 0 32 4 13 NA NA NA NA NA NA NA 19190 FUN_001098 4686 4399 1715 3799 2491 NA NA NA NA NA NA NA 19191 FUN_040798 0 0 26 3 0 NA NA NA NA NA NA NA 19192 FUN_040799 0 0 0 66 0 NA NA NA NA NA NA NA 19193 FUN_035927 7 0 24 1 119 NA NA NA NA NA NA NA 19194 FUN_035926 324 395 329 296 506 ptg000025l:13344820-13348234 A3KG59 5.71e-52 Xaa-Arg dipeptidase (EC 3.4.13.4) Mus musculus (Mouse) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 19195 FUN_035924 17 10 6 26 33 NA NA NA NA NA NA NA 19196 FUN_035923 1428 1092 1512 1270 2489 NA NA NA NA NA NA NA 19197 FUN_035922 5619 1516 442 1478 993 NA NA NA NA NA NA NA 19198 FUN_035921 0 0 19 31 52 ptg000025l:13318826-13326869 P22105 2.88e-27 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 19199 FUN_035921 0 0 19 31 52 ptg000025l:13318826-13326869 P22105 1.07e-22 Tenascin-X (TN-X) (Hexabrachion-like protein) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell-matrix adhesion [GO:0007160]; collagen fibril organization [GO:0030199]; collagen metabolic process [GO:0032963]; elastic fiber assembly [GO:0048251]; extracellular matrix organization [GO:0030198]; fatty acid metabolic process [GO:0006631]; positive regulation of cell fate determination [GO:1905935]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen fibril organization [GO:1904028]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of transforming growth factor beta activation [GO:1901390]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; regulation of JUN kinase activity [GO:0043506]; triglyceride metabolic process [GO:0006641] GO:0005178; GO:0005201; GO:0005518; GO:0005576; GO:0005615; GO:0006631; GO:0006641; GO:0007155; GO:0007160; GO:0008201; GO:0008284; GO:0010718; GO:0010862; GO:0030036; GO:0030155; GO:0030198; GO:0030199; GO:0030334; GO:0030511; GO:0031012; GO:0032963; GO:0043506; GO:0045595; GO:0048251; GO:0062023; GO:0070062; GO:0090733; GO:0098609; GO:0098633; GO:1900748; GO:1901390; GO:1904028; GO:1905935 19200 FUN_035929 1045 1832 538 680 521 NA NA NA NA NA NA NA 19201 FUN_035928 768 138 170 264 142 ptg000025l:13355407-13357446 A3KG59 9.55e-49 Xaa-Arg dipeptidase (EC 3.4.13.4) Mus musculus (Mouse) proteolysis [GO:0006508]; regulation of protein metabolic process [GO:0051246] GO:0004180; GO:0005654; GO:0006508; GO:0016805; GO:0042802; GO:0051246 19202 FUN_004383 50 16 62 12 100 NA NA NA NA NA NA NA 19203 FUN_004382 0 2 9 14 15 NA NA NA NA NA NA NA 19204 FUN_004380 20 0 10 20 162 NA NA NA NA NA NA NA 19205 FUN_004387 173 74 115 56 327 NA NA NA NA NA NA NA 19206 FUN_004386 105 137 79 164 266 NA NA NA NA NA NA NA 19207 FUN_004385 472 365 389 368 1345 NA NA NA NA NA NA NA 19208 FUN_004384 3514 1279 2138 2094 3276 NA NA NA NA NA NA NA 19209 FUN_004389 276 302 326 126 728 NA NA NA NA NA NA NA 19210 FUN_012804 0 0 20 35 245 NA NA NA NA NA NA NA 19211 FUN_034032 80 8 26 37 38 ptg000024l:3981549-3983946 P52569 2.51e-65 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 19212 FUN_018422 216 533 217 185 394 NA NA NA NA NA NA NA 19213 FUN_018421 0 11 36 29 0 NA NA NA NA NA NA NA 19214 FUN_018427 23 10 0 37 27 NA NA NA NA NA NA NA 19215 FUN_018426 0 25 0 0 54 NA NA NA NA NA NA NA 19216 FUN_018425 25221 44013 11775 28123 12575 ptg000012l:9121437-9124594 Q9GT45 1.37e-26 40S ribosomal protein S26 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003729; GO:0003735; GO:0022627; GO:0042788; GO:0098556 19217 FUN_018424 6346 9653 3607 6949 7882 ptg000012l:9116226-9121237 P24156 1.62e-24 Protein l(2)37Cc Drosophila melanogaster (Fruit fly) cellular response to hypoxia [GO:0071456]; mitochondrion organization [GO:0007005] GO:0005739; GO:0007005; GO:0016020; GO:0071456 19218 FUN_018429 621 1166 433 815 487 ptg000012l:9174919-9186013 P20664 4.06e-23 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 19219 FUN_034039 31071 40201 25620 29947 8418 NA NA NA NA NA NA NA 19220 FUN_006839 0 31 4 23 35 NA NA NA NA NA NA NA 19221 FUN_006837 1465 82 149 215 34 NA NA NA NA NA NA NA 19222 FUN_006836 0 6 0 0 33 NA NA NA NA NA NA NA 19223 FUN_006835 92 0 4 33 33 NA NA NA NA NA NA NA 19224 FUN_006833 7910 31507 13766 6629 5336 NA NA NA NA NA NA NA 19225 FUN_006832 7 5 26 0 24 NA NA NA NA NA NA NA 19226 FUN_006831 26 6 6 55 24 NA NA NA NA NA NA NA 19227 FUN_006830 456 99 330 595 366 NA NA NA NA NA NA NA 19228 FUN_016397 2183 1277 767 1397 1632 NA NA NA NA NA NA NA 19229 FUN_035075 243 217 220 196 91 ptg000025l:3497003-3500391 E7FAM5 1.04e-75 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19230 FUN_035074 452 172 156 516 454 NA NA NA NA NA NA NA 19231 FUN_035077 493 284 179 296 120 ptg000025l:3515390-3525001 E7FAM5 7.05e-74 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19232 FUN_035076 309 216 18 184 46 ptg000025l:3506194-3508896 E7FAM5 3.34e-86 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19233 FUN_035071 6200 11855 8232 5534 3232 ptg000025l:3466902-3467991 E2R4X3 1.71e-24 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1) Canis lupus familiaris (Dog) (Canis familiaris) protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487] GO:0006486; GO:0006487; GO:0008250 19234 FUN_035070 403 373 260 337 310 ptg000025l:3465229-3466602 Q9CY94 5.23e-30 DNA replication complex GINS protein PSF3 (GINS complex subunit 3) Mus musculus (Mouse) DNA unwinding involved in DNA replication [GO:0006268]; mitotic DNA replication initiation [GO:1902975]; positive regulation of DNA primase activity [GO:1903934]; positive regulation of DNA-directed DNA polymerase activity [GO:1900264] GO:0000811; GO:0005634; GO:0005654; GO:0006268; GO:0071162; GO:1900264; GO:1902975; GO:1903934 19235 FUN_035073 130 16 70 185 160 ptg000025l:3485528-3488321 E7FAM5 1.03e-89 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19236 FUN_035072 942 314 543 441 560 ptg000025l:3470654-3485281 A1L1P9 1.25e-25 Multidrug and toxin extrusion protein 1 (MATE-1) (Solute carrier family 47 member 1) Danio rerio (Zebrafish) (Brachydanio rerio) organic cation transport [GO:0015695]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961] GO:0015101; GO:0015297; GO:0015695; GO:0016020; GO:0016324; GO:0022857; GO:0042910; GO:1990961 19237 FUN_016390 64 0 9 0 0 NA NA NA NA NA NA NA 19238 FUN_035079 200 10 0 46 42 ptg000025l:3540132-3548846 E7FAM5 8.49e-67 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19239 FUN_035079 200 10 0 46 42 ptg000025l:3540132-3548846 E7FAM5 3.01e-44 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19240 FUN_035079 200 10 0 46 42 ptg000025l:3540132-3548846 E7FAM5 1.34e-35 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19241 FUN_035079 200 10 0 46 42 ptg000025l:3540132-3548846 E7FAM5 1.72e-21 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 19242 FUN_035078 0 5 8 0 0 NA NA NA NA NA NA NA 19243 FUN_028107 986 541 293 729 548 ptg000021l:15851165-15860945 Q5JCS6 3.75e-24 Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2) (Serine-rich synapse-associated protein) Rattus norvegicus (Rat) activation of GTPase activity [GO:0090630]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0005096; GO:0005737; GO:0051056; GO:0090630 19244 FUN_028106 0 9 11 8 17 NA NA NA NA NA NA NA 19245 FUN_028105 1032 364 288 1144 1236 NA NA NA NA NA NA NA 19246 FUN_028104 3495 4516 1476 3397 1869 NA NA NA NA NA NA NA 19247 FUN_028103 865 416 402 491 406 NA NA NA NA NA NA NA 19248 FUN_028102 2 0 4 6 136 NA NA NA NA NA NA NA 19249 FUN_028100 3350 2064 1506 4291 3701 ptg000021l:15804941-15814859 Q7ZUW2 4.23e-32 Hypoxia up-regulated protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hypoxia [GO:0071456]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298] GO:0005524; GO:0005788; GO:0034663; GO:0071456; GO:0140662; GO:1903298 19250 FUN_028100 3350 2064 1506 4291 3701 ptg000021l:15804941-15814859 Q7ZUW2 4.23e-32 Hypoxia up-regulated protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hypoxia [GO:0071456]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298] GO:0005524; GO:0005788; GO:0034663; GO:0071456; GO:0140662; GO:1903298 19251 FUN_028100 3350 2064 1506 4291 3701 ptg000021l:15804941-15814859 Q7ZUW2 4.23e-32 Hypoxia up-regulated protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hypoxia [GO:0071456]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298] GO:0005524; GO:0005788; GO:0034663; GO:0071456; GO:0140662; GO:1903298 19252 FUN_028100 3350 2064 1506 4291 3701 ptg000021l:15804941-15814859 Q7ZUW2 4.23e-32 Hypoxia up-regulated protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to hypoxia [GO:0071456]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298] GO:0005524; GO:0005788; GO:0034663; GO:0071456; GO:0140662; GO:1903298 19253 FUN_028109 6068 4732 2713 5949 4457 ptg000021l:15871050-15880396 Q9U5L1 2.43e-26 Signal recognition particle receptor subunit alpha homolog (DP-alpha) (Docking protein alpha) (SR-alpha) (GTP-binding protein) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; protein targeting [GO:0006605]; protein targeting to ER [GO:0045047]; regulation of protein secretion [GO:0050708]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0003723; GO:0003924; GO:0005047; GO:0005525; GO:0005785; GO:0005789; GO:0006605; GO:0006614; GO:0007409; GO:0012505; GO:0016020; GO:0045047; GO:0050708 19254 FUN_028109 6068 4732 2713 5949 4457 ptg000021l:15871050-15880396 Q9U5L1 2.21e-21 Signal recognition particle receptor subunit alpha homolog (DP-alpha) (Docking protein alpha) (SR-alpha) (GTP-binding protein) Drosophila melanogaster (Fruit fly) axonogenesis [GO:0007409]; protein targeting [GO:0006605]; protein targeting to ER [GO:0045047]; regulation of protein secretion [GO:0050708]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614] GO:0003723; GO:0003924; GO:0005047; GO:0005525; GO:0005785; GO:0005789; GO:0006605; GO:0006614; GO:0007409; GO:0012505; GO:0016020; GO:0045047; GO:0050708 19255 FUN_007128 7 2 15 33 19 NA NA NA NA NA NA NA 19256 FUN_007129 50 245 124 19 139 NA NA NA NA NA NA NA 19257 FUN_007122 1351 807 732 1518 1006 NA NA NA NA NA NA NA 19258 FUN_007123 105 13 5 81 40 NA NA NA NA NA NA NA 19259 FUN_007120 5268 7514 3991 4226 2758 NA NA NA NA NA NA NA 19260 FUN_007121 146 129 80 99 186 NA NA NA NA NA NA NA 19261 FUN_007126 411 525 245 404 822 ptg000001l:20775023-20780897 P21328 6.29e-29 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19262 FUN_007127 0 0 0 21 20 NA NA NA NA NA NA NA 19263 FUN_007124 2333 2012 1778 3806 2807 NA NA NA NA NA NA NA 19264 FUN_007125 2450 1997 1221 1827 1073 NA NA NA NA NA NA NA 19265 FUN_043364 77 126 67 80 78 NA NA NA NA NA NA NA 19266 FUN_043365 853 302 231 473 319 NA NA NA NA NA NA NA 19267 FUN_043366 297 181 131 191 182 NA NA NA NA NA NA NA 19268 FUN_043367 115 12 4 9 24 ptg000047l:7631374-7636559 Q4UMH6 1.87e-24 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 19269 FUN_043367 115 12 4 9 24 ptg000047l:7631374-7636559 Q4UMH6 3.32e-22 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 19270 FUN_043360 48 3 11 0 0 NA NA NA NA NA NA NA 19271 FUN_043362 910 573 411 372 443 NA NA NA NA NA NA NA 19272 FUN_043363 6838 7009 3442 4321 4064 ptg000047l:7588057-7594946 Q8C4Y3 2.92e-92 Negative elongation factor B (NELF-B) (Cofactor of BRCA1) Mus musculus (Mouse) cell population proliferation [GO:0008283]; negative regulation of stem cell differentiation [GO:2000737]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; stem cell differentiation [GO:0048863] GO:0003723; GO:0005634; GO:0005737; GO:0005741; GO:0005829; GO:0008283; GO:0032021; GO:0034244; GO:0048863; GO:2000737 19273 FUN_016398 2047 162 3 0 5 NA NA NA NA NA NA NA 19274 FUN_043368 580 419 577 530 529 NA NA NA NA NA NA NA 19275 FUN_043369 1080 546 445 1236 1178 ptg000047l:7645234-7658903 Q6NZR5 8.28e-33 NA NA NA NA 19276 FUN_042095 0 0 0 0 6 NA NA NA NA NA NA NA 19277 FUN_042094 76 422 56 328 106 NA NA NA NA NA NA NA 19278 FUN_042097 32 78 18 126 0 ptg000036l:540473-542666 Q96CG8 2.68e-30 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 19279 FUN_042096 78 11 0 7 45 NA NA NA NA NA NA NA 19280 FUN_042090 0 0 0 13 0 ptg000036l:467261-472185 P08548 8.77e-32 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 19281 FUN_013374 27 0 195 18 7 NA NA NA NA NA NA NA 19282 FUN_013375 0 18 37 6 0 NA NA NA NA NA NA NA 19283 FUN_013372 9 0 0 0 0 NA NA NA NA NA NA NA 19284 FUN_013373 1402 874 844 1894 1253 NA NA NA NA NA NA NA 19285 FUN_041211 3212 5164 2122 7475 3687 NA NA NA NA NA NA NA 19286 FUN_017912 71 67 24 81 79 NA NA NA NA NA NA NA 19287 FUN_003926 65 0 51 135 57 NA NA NA NA NA NA NA 19288 FUN_003927 101 18 108 114 123 NA NA NA NA NA NA NA 19289 FUN_003924 11 0 0 21 53 NA NA NA NA NA NA NA 19290 FUN_003925 2800 839 1558 4440 2861 NA NA NA NA NA NA NA 19291 FUN_003923 129 35 54 31 17 NA NA NA NA NA NA NA 19292 FUN_003920 11 20 9 5 3 NA NA NA NA NA NA NA 19293 FUN_003921 128 22 36 18 10 NA NA NA NA NA NA NA 19294 FUN_036522 251 5 144 213 10 NA NA NA NA NA NA NA 19295 FUN_036523 551 285 247 376 268 ptg000025l:19255535-19257209 A7SGU3 1.19e-95 Dynactin subunit 6 Nematostella vectensis (Starlet sea anemone) mitotic spindle organization [GO:0007052] GO:0005737; GO:0005869; GO:0007052; GO:0070840 19296 FUN_036521 717 188 454 709 72 ptg000025l:19214926-19253047 P10978 1.23e-21 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 19297 FUN_036521 717 188 454 709 72 ptg000025l:19214926-19253047 P10978 1.23e-21 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 19298 FUN_036524 1745 683 1009 1236 223 NA NA NA NA NA NA NA 19299 FUN_002039 0 3 0 18 0 NA NA NA NA NA NA NA 19300 FUN_002038 0 0 0 0 27 NA NA NA NA NA NA NA 19301 FUN_002033 4 85 0 0 98 NA NA NA NA NA NA NA 19302 FUN_002037 9 0 1 0 10 NA NA NA NA NA NA NA 19303 FUN_002034 4 40 15 0 65 NA NA NA NA NA NA NA 19304 FUN_022085 59 0 14 21 15 NA NA NA NA NA NA NA 19305 FUN_042542 3 0 8 0 10 ptg000038l:74411-76525 Q6LAF1 5.15e-45 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19306 FUN_042541 0 0 0 13 1 NA NA NA NA NA NA NA 19307 FUN_012964 403 2 10 241 0 NA NA NA NA NA NA NA 19308 FUN_012965 0 0 0 0 23 NA NA NA NA NA NA NA 19309 FUN_012963 610 0 0 279 0 NA NA NA NA NA NA NA 19310 FUN_012968 358 206 46 718 251 NA NA NA NA NA NA NA 19311 FUN_012969 1363 1313 679 1497 1009 NA NA NA NA NA NA NA 19312 FUN_034324 51 41 23 123 27 NA NA NA NA NA NA NA 19313 FUN_032315 2915 2624 1859 2967 2643 ptg000023l:30791453-30798471 O14730 1.9e-28 Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog) Homo sapiens (Human) cellular response to dsDNA [GO:1990786]; cellular response to dsRNA [GO:0071359]; cellular response to virus [GO:0098586]; chromosome segregation [GO:0007059]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; maturation of SSU-rRNA [GO:0030490]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of MDA-5 signaling pathway [GO:0039534]; negative regulation of protein-containing complex assembly [GO:0031333]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005829; GO:0006468; GO:0007059; GO:0030490; GO:0030688; GO:0031333; GO:0032728; GO:0039534; GO:0043124; GO:0045087; GO:0045089; GO:0046872; GO:0051607; GO:0071359; GO:0089720; GO:0098586; GO:0106310; GO:1990786 19314 FUN_032314 14436 9621 10761 19241 12143 NA NA NA NA NA NA NA 19315 FUN_032317 794 739 873 774 904 NA NA NA NA NA NA NA 19316 FUN_032316 423 204 127 176 298 NA NA NA NA NA NA NA 19317 FUN_032311 1 7 0 0 0 NA NA NA NA NA NA NA 19318 FUN_032310 730 479 294 454 456 NA NA NA NA NA NA NA 19319 FUN_032313 6856 5423 3016 5298 3700 NA NA NA NA NA NA NA 19320 FUN_032312 1029 492 180 500 425 NA NA NA NA NA NA NA 19321 FUN_032319 25 0 0 23 42 NA NA NA NA NA NA NA 19322 FUN_008599 566 117 268 196 301 NA NA NA NA NA NA NA 19323 FUN_026904 20 60 27 644 210 NA NA NA NA NA NA NA 19324 FUN_008592 535 123 113 342 277 ptg000002l:13238523-13257259 Q6PDJ1 8.31e-23 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 19325 FUN_008593 433 200 164 273 100 ptg000002l:13262365-13304992 Q6PDJ1 7.94e-25 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 19326 FUN_008590 18 16 44 253 100 ptg000002l:13206253-13220214 Q6PDJ1 4.36e-25 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 19327 FUN_008591 692 132 173 248 200 ptg000002l:13221626-13235595 Q6PDJ1 5.86e-25 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 19328 FUN_008596 59 44 42 69 60 NA NA NA NA NA NA NA 19329 FUN_008594 1371 704 555 1358 1253 ptg000002l:13308220-13333011 Q01635 7.35e-25 Laminin subunit beta-1 (Laminin beta-1-1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Gallus gallus (Chicken) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; negative regulation of cell adhesion [GO:0007162]; neuron projection development [GO:0031175]; positive regulation of cell migration [GO:0030335]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005201; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0007162; GO:0009887; GO:0009888; GO:0016477; GO:0030335; GO:0031175; GO:0034446; GO:0043256; GO:0043257; GO:0043259; GO:0048471; GO:0070831 19330 FUN_008594 1371 704 555 1358 1253 ptg000002l:13308220-13333011 Q01635 9.05e-25 Laminin subunit beta-1 (Laminin beta-1-1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) Gallus gallus (Chicken) animal organ morphogenesis [GO:0009887]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; negative regulation of cell adhesion [GO:0007162]; neuron projection development [GO:0031175]; positive regulation of cell migration [GO:0030335]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005178; GO:0005201; GO:0005604; GO:0005606; GO:0005607; GO:0005615; GO:0007162; GO:0009887; GO:0009888; GO:0016477; GO:0030335; GO:0031175; GO:0034446; GO:0043256; GO:0043257; GO:0043259; GO:0048471; GO:0070831 19331 FUN_008595 84 41 61 71 218 NA NA NA NA NA NA NA 19332 FUN_011266 0 47 43 35 205 NA NA NA NA NA NA NA 19333 FUN_000368 0 0 60 45 29 NA NA NA NA NA NA NA 19334 FUN_011264 17753 22516 11490 23794 17806 NA NA NA NA NA NA NA 19335 FUN_011262 4 82 7 20 0 NA NA NA NA NA NA NA 19336 FUN_011263 1464 464 385 420 206 NA NA NA NA NA NA NA 19337 FUN_011260 3597 2453 1701 2696 2210 ptg000007l:8301619-8321446 Q6PF69 3.03e-30 Major vault protein (MVP) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:1990904 19338 FUN_011260 3597 2453 1701 2696 2210 ptg000007l:8301619-8321446 Q6PF69 3.42e-25 Major vault protein (MVP) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:1990904 19339 FUN_000360 0 0 18 0 6 NA NA NA NA NA NA NA 19340 FUN_000363 0 0 4 14 0 NA NA NA NA NA NA NA 19341 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 7.61e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19342 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 2.33e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19343 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 6.49e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19344 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 4.96e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19345 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 1.57e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19346 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 1.11e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19347 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 6.68e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19348 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 5.06e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19349 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 8.58e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19350 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 3.05e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19351 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 3.73e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19352 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 1.16e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19353 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 2.33e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19354 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 6.69e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19355 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 1.86e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19356 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 2.04e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19357 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 4.68e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19358 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 2.69e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19359 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 8.35e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19360 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 3.84e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19361 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 4.66e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19362 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 9.2e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19363 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 9.2e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19364 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 2.55e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19365 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 5.33e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19366 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 1.29e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19367 FUN_000362 0 161 24 344 25 ntLink_6:2051201-2067355 Q96AY4 1.11e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19368 FUN_000367 86 9 78 116 6 NA NA NA NA NA NA NA 19369 FUN_000366 0 0 288 420 40 NA NA NA NA NA NA NA 19370 FUN_026902 698 438 362 564 344 NA NA NA NA NA NA NA 19371 FUN_008628 6 0 44 3 0 NA NA NA NA NA NA NA 19372 FUN_008629 1468 2625 953 1258 1083 NA NA NA NA NA NA NA 19373 FUN_008624 29 0 20 0 0 NA NA NA NA NA NA NA 19374 FUN_008625 85 7 0 40 0 NA NA NA NA NA NA NA 19375 FUN_008626 0 27 0 0 20 NA NA NA NA NA NA NA 19376 FUN_008627 0 0 0 0 19 NA NA NA NA NA NA NA 19377 FUN_008620 772 643 545 1176 1062 NA NA NA NA NA NA NA 19378 FUN_008621 189 161 287 317 157 NA NA NA NA NA NA NA 19379 FUN_008622 0 0 10 33 7 NA NA NA NA NA NA NA 19380 FUN_008623 1274 1204 841 811 880 NA NA NA NA NA NA NA 19381 FUN_029078 2738 2101 1520 2411 1828 ptg000022l:7964533-7968272 Q58CN9 2.77e-81 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Bos taurus (Bovine) host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; phospholipid catabolic process [GO:0009395]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001659; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200 19382 FUN_029079 59 102 61 118 161 NA NA NA NA NA NA NA 19383 FUN_029074 0 24 33 104 16 NA NA NA NA NA NA NA 19384 FUN_029075 0 19 12 111 35 NA NA NA NA NA NA NA 19385 FUN_029076 0 0 0 0 7 NA NA NA NA NA NA NA 19386 FUN_029077 0 0 11 0 90 NA NA NA NA NA NA NA 19387 FUN_029070 143 0 40 49 27 NA NA NA NA NA NA NA 19388 FUN_029071 164 88 34 224 244 NA NA NA NA NA NA NA 19389 FUN_029073 0 0 44 23 10 NA NA NA NA NA NA NA 19390 FUN_033048 1869 1239 1697 2333 963 NA NA NA NA NA NA NA 19391 FUN_014867 40 24 77 67 41 NA NA NA NA NA NA NA 19392 FUN_033042 0 0 0 16 0 NA NA NA NA NA NA NA 19393 FUN_033043 0 169 267 344 223 ptg000023l:39237917-39288391 P46023 2.74e-74 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 19394 FUN_033040 16 0 0 35 0 ptg000023l:39176701-39192258 P58158 1.8e-33 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 3) (Glucuronosyltransferase I) (GlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; positive regulation of catalytic activity [GO:0043085]; positive regulation of intracellular protein transport [GO:0090316]; protein glycosylation [GO:0006486] GO:0000139; GO:0005794; GO:0005801; GO:0005975; GO:0006024; GO:0006486; GO:0015012; GO:0015018; GO:0015020; GO:0043085; GO:0046872; GO:0050650; GO:0050651; GO:0072542; GO:0090316 19395 FUN_033041 69 0 0 19 64 NA NA NA NA NA NA NA 19396 FUN_033046 8 0 15 0 30 NA NA NA NA NA NA NA 19397 FUN_033047 204 341 60 37 195 NA NA NA NA NA NA NA 19398 FUN_039000 0 0 0 0 6 NA NA NA NA NA NA NA 19399 FUN_039001 14 0 20 0 18 NA NA NA NA NA NA NA 19400 FUN_039003 22 11 8 34 46 NA NA NA NA NA NA NA 19401 FUN_039005 0 0 0 0 46 NA NA NA NA NA NA NA 19402 FUN_039007 14 0 6 0 62 NA NA NA NA NA NA NA 19403 FUN_033920 1589 1434 453 774 190 NA NA NA NA NA NA NA 19404 FUN_014864 10432 10989 6992 9696 4700 NA NA NA NA NA NA NA 19405 FUN_008297 35 5441 16 14 6169 NA NA NA NA NA NA NA 19406 FUN_014863 3870 4019 2114 3304 3269 NA NA NA NA NA NA NA 19407 FUN_008296 2086 1577 1473 2650 1915 ptg000002l:10054447-10061170 Q9DBY1 5.54e-41 E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1) Mus musculus (Mouse) ERAD pathway [GO:0036503]; immature B cell differentiation [GO:0002327]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; protein catabolic process [GO:0030163]; protein K48-linked ubiquitination [GO:0070936]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000839; GO:0001701; GO:0002327; GO:0005654; GO:0005783; GO:0005790; GO:0006511; GO:0006986; GO:0016567; GO:0030163; GO:0030433; GO:0030970; GO:0036503; GO:0036513; GO:0044322; GO:0046872; GO:0050821; GO:0051082; GO:0051087; GO:0051117; GO:0061630; GO:0070059; GO:0070936; GO:1902236; GO:1990381 19408 FUN_008296 2086 1577 1473 2650 1915 ptg000002l:10054447-10061170 Q9DBY1 1.65e-33 E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1) Mus musculus (Mouse) ERAD pathway [GO:0036503]; immature B cell differentiation [GO:0002327]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; protein catabolic process [GO:0030163]; protein K48-linked ubiquitination [GO:0070936]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000839; GO:0001701; GO:0002327; GO:0005654; GO:0005783; GO:0005790; GO:0006511; GO:0006986; GO:0016567; GO:0030163; GO:0030433; GO:0030970; GO:0036503; GO:0036513; GO:0044322; GO:0046872; GO:0050821; GO:0051082; GO:0051087; GO:0051117; GO:0061630; GO:0070059; GO:0070936; GO:1902236; GO:1990381 19409 FUN_008296 2086 1577 1473 2650 1915 ptg000002l:10054447-10061170 Q9DBY1 1.65e-33 E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1) Mus musculus (Mouse) ERAD pathway [GO:0036503]; immature B cell differentiation [GO:0002327]; in utero embryonic development [GO:0001701]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; protein catabolic process [GO:0030163]; protein K48-linked ubiquitination [GO:0070936]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; response to unfolded protein [GO:0006986]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000839; GO:0001701; GO:0002327; GO:0005654; GO:0005783; GO:0005790; GO:0006511; GO:0006986; GO:0016567; GO:0030163; GO:0030433; GO:0030970; GO:0036503; GO:0036513; GO:0044322; GO:0046872; GO:0050821; GO:0051082; GO:0051087; GO:0051117; GO:0061630; GO:0070059; GO:0070936; GO:1902236; GO:1990381 19410 FUN_010618 617 1005 365 326 165 NA NA NA NA NA NA NA 19411 FUN_010614 2004 2229 1197 2421 1785 ptg000007l:690620-698931 A7SWH1 7.35e-34 Pescadillo homolog Nematostella vectensis (Starlet sea anemone) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000466]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] GO:0000463; GO:0000466; GO:0003723; GO:0005654; GO:0030687; GO:0043021; GO:0070545 19412 FUN_010615 178 89 165 145 154 NA NA NA NA NA NA NA 19413 FUN_010616 6559 3505 2275 3461 2913 NA NA NA NA NA NA NA 19414 FUN_010610 2739 608 268 409 2193 NA NA NA NA NA NA NA 19415 FUN_010612 1180 980 734 1085 1321 NA NA NA NA NA NA NA 19416 FUN_010613 217 208 150 271 332 NA NA NA NA NA NA NA 19417 FUN_042651 252 356 186 386 603 NA NA NA NA NA NA NA 19418 FUN_012106 2859 1818 3296 2651 2395 NA NA NA NA NA NA NA 19419 FUN_012104 829 615 625 766 422 NA NA NA NA NA NA NA 19420 FUN_012105 37400 15127 21380 7029 7698 NA NA NA NA NA NA NA 19421 FUN_012102 1190 622 814 1696 1035 NA NA NA NA NA NA NA 19422 FUN_012103 688 425 394 786 801 NA NA NA NA NA NA NA 19423 FUN_012100 889 668 346 684 667 NA NA NA NA NA NA NA 19424 FUN_012101 1103 938 607 1489 1445 ptg000008l:5102971-5119062 Q5B6H7 7.78e-35 Presequence protease, mitochondrial (PreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) cellular response to farnesol [GO:0097308]; protein processing [GO:0016485]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004222; GO:0005758; GO:0005759; GO:0008270; GO:0016485; GO:0051603; GO:0097308 19425 FUN_012101 1103 938 607 1489 1445 ptg000008l:5102971-5119062 Q5B6H7 7.78e-35 Presequence protease, mitochondrial (PreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) cellular response to farnesol [GO:0097308]; protein processing [GO:0016485]; proteolysis involved in protein catabolic process [GO:0051603] GO:0004222; GO:0005758; GO:0005759; GO:0008270; GO:0016485; GO:0051603; GO:0097308 19426 FUN_012108 499 355 252 553 432 NA NA NA NA NA NA NA 19427 FUN_012109 2756 2029 1679 2451 1774 ptg000008l:5208911-5214121 O43390 1.07e-62 Heterogeneous nuclear ribonucleoprotein R (hnRNP R) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005783; GO:0006397; GO:0071013; GO:1990904 19428 FUN_012109 2756 2029 1679 2451 1774 ptg000008l:5208911-5214121 O43390 3.01e-44 Heterogeneous nuclear ribonucleoprotein R (hnRNP R) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005783; GO:0006397; GO:0071013; GO:1990904 19429 FUN_030073 1038 2621 1876 3857 1576 NA NA NA NA NA NA NA 19430 FUN_014861 1069 501 892 2722 679 NA NA NA NA NA NA NA 19431 FUN_030070 0 7 0 58 0 NA NA NA NA NA NA NA 19432 FUN_008298 883 737 396 524 534 ptg000002l:10085650-10090702 Q90718 2.67e-36 Serum response factor (SRF) Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0010736; GO:0030036; GO:0045944; GO:0046983 19433 FUN_020808 3 0 1 0 101 NA NA NA NA NA NA NA 19434 FUN_020804 0 0 7 0 0 NA NA NA NA NA NA NA 19435 FUN_020805 4 0 0 0 34 NA NA NA NA NA NA NA 19436 FUN_020803 0 22 0 0 0 NA NA NA NA NA NA NA 19437 FUN_020800 0 0 0 13 0 NA NA NA NA NA NA NA 19438 FUN_020801 0 0 0 0 23 ptg000015l:8818435-8825610 Q03278 8.2e-39 Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nasonia vitripennis (Parasitic wasp) NA GO:0003964; GO:0004519; GO:0046872 19439 FUN_020801 0 0 0 0 23 ptg000015l:8818435-8825610 Q03278 8.2e-39 Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nasonia vitripennis (Parasitic wasp) NA GO:0003964; GO:0004519; GO:0046872 19440 FUN_020801 0 0 0 0 23 ptg000015l:8818435-8825610 Q03278 8.2e-39 Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Retrovirus-related Pol polyprotein from type I retrotransposable element R2) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nasonia vitripennis (Parasitic wasp) NA GO:0003964; GO:0004519; GO:0046872 19441 FUN_042658 18 13 13 4 1 NA NA NA NA NA NA NA 19442 FUN_019417 5 43 87 70 111 NA NA NA NA NA NA NA 19443 FUN_014860 353 136 191 275 125 NA NA NA NA NA NA NA 19444 FUN_019416 0 0 16 0 91 NA NA NA NA NA NA NA 19445 FUN_038839 11 5 0 4 0 NA NA NA NA NA NA NA 19446 FUN_038836 0 0 0 66 0 NA NA NA NA NA NA NA 19447 FUN_038834 1157 896 722 1169 642 NA NA NA NA NA NA NA 19448 FUN_038835 2802 4390 3403 6018 4587 NA NA NA NA NA NA NA 19449 FUN_038832 1432 1554 737 1917 1199 NA NA NA NA NA NA NA 19450 FUN_038833 3621 1380 983 2504 1998 ptg000027l:11854909-11863363 Q9YGY0 1.15e-23 Axin-1 (Axis inhibition protein 1) (xAxin) Xenopus laevis (African clawed frog) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification [GO:2000054]; positive regulation of JNK cascade [GO:0046330]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005737; GO:0005886; GO:0016055; GO:0042803; GO:0046330; GO:0090090; GO:2000054 19451 FUN_038830 11 0 0 14 2 NA NA NA NA NA NA NA 19452 FUN_038831 1343 672 940 1343 1205 ptg000027l:11788516-11814488 P84239 2.22e-83 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19453 FUN_030079 6 22 7 29 17 NA NA NA NA NA NA NA 19454 FUN_042823 1640 1487 993 1932 1330 ptg000047l:589738-591687 Q5RA81 1.02e-57 GrpE protein homolog 1, mitochondrial (Mt-GrpE#1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein folding [GO:0006457] GO:0000774; GO:0005654; GO:0005759; GO:0006457; GO:0042803; GO:0051082; GO:0051087 19455 FUN_023384 661 31 479 226 1191 NA NA NA NA NA NA NA 19456 FUN_014624 11376 8233 5004 10704 6428 ptg000009l:1666181-1669491 Q6NVU2 3.29e-62 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear membrane reassembly [GO:0007084]; protein dephosphorylation [GO:0006470] GO:0000776; GO:0004722; GO:0005730; GO:0005739; GO:0005856; GO:0005977; GO:0006470; GO:0007084; GO:0016607; GO:0017018; GO:0030496; GO:0032154; GO:0046872; GO:0051301 19457 FUN_014624 11376 8233 5004 10704 6428 ptg000009l:1666181-1669491 Q6NVU2 3.29e-62 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear membrane reassembly [GO:0007084]; protein dephosphorylation [GO:0006470] GO:0000776; GO:0004722; GO:0005730; GO:0005739; GO:0005856; GO:0005977; GO:0006470; GO:0007084; GO:0016607; GO:0017018; GO:0030496; GO:0032154; GO:0046872; GO:0051301 19458 FUN_014624 11376 8233 5004 10704 6428 ptg000009l:1666181-1669491 Q6NVU2 3.29e-62 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear membrane reassembly [GO:0007084]; protein dephosphorylation [GO:0006470] GO:0000776; GO:0004722; GO:0005730; GO:0005739; GO:0005856; GO:0005977; GO:0006470; GO:0007084; GO:0016607; GO:0017018; GO:0030496; GO:0032154; GO:0046872; GO:0051301 19459 FUN_014624 11376 8233 5004 10704 6428 ptg000009l:1666181-1669491 Q6NVU2 6.29e-22 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; mitotic nuclear membrane reassembly [GO:0007084]; protein dephosphorylation [GO:0006470] GO:0000776; GO:0004722; GO:0005730; GO:0005739; GO:0005856; GO:0005977; GO:0006470; GO:0007084; GO:0016607; GO:0017018; GO:0030496; GO:0032154; GO:0046872; GO:0051301 19460 FUN_023386 67 34 85 73 34 NA NA NA NA NA NA NA 19461 FUN_014626 68794 77179 43197 48805 21735 ptg000009l:1685420-1686086 Q78P75 6.63e-59 Dynein light chain 2, cytoplasmic (Dynein light chain LC8-type 2) Rattus norvegicus (Rat) microtubule-based process [GO:0007017] GO:0005737; GO:0005813; GO:0005856; GO:0005868; GO:0005874; GO:0007017; GO:0014069; GO:0031475; GO:0042802; GO:0044877; GO:0045505; GO:0097110; GO:0097731; GO:0098794; GO:0098978 19462 FUN_014621 806 926 794 837 556 NA NA NA NA NA NA NA 19463 FUN_014620 906 482 130 438 637 NA NA NA NA NA NA NA 19464 FUN_014623 3462 4382 1882 2943 2421 NA NA NA NA NA NA NA 19465 FUN_014622 622 587 228 408 749 NA NA NA NA NA NA NA 19466 FUN_023388 636 992 492 1355 906 NA NA NA NA NA NA NA 19467 FUN_023389 216 68 28 45 50 ptg000017l:6989945-6991097 Q8VCR7 1.04e-38 Putative protein-lysine deacylase ABHD14B (EC 2.3.1.-) (Alpha/beta hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) Mus musculus (Mouse) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0016746; GO:0016787; GO:0045944 19468 FUN_033805 10 18 0 2 23 NA NA NA NA NA NA NA 19469 FUN_013962 0 0 0 67 14 NA NA NA NA NA NA NA 19470 FUN_025971 683 812 216 434 155 NA NA NA NA NA NA NA 19471 FUN_025970 4960 4070 2761 4716 4238 NA NA NA NA NA NA NA 19472 FUN_025973 1167 1032 474 2359 1038 NA NA NA NA NA NA NA 19473 FUN_025975 2327 1029 589 1704 1332 NA NA NA NA NA NA NA 19474 FUN_025974 288 305 93 458 225 NA NA NA NA NA NA NA 19475 FUN_025977 855 508 169 447 483 ptg000020l:2738437-2742676 P48963 3.89e-50 Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) Mesocricetus auratus (Golden hamster) cell division [GO:0051301]; DNA repair [GO:0006281]; meiotic cell cycle [GO:0051321]; protein phosphorylation [GO:0006468] GO:0004693; GO:0005524; GO:0005768; GO:0005815; GO:0006281; GO:0006468; GO:0015030; GO:0046872; GO:0051301; GO:0051321; GO:0097472; GO:0106310 19476 FUN_009501 5 4 0 2 9 NA NA NA NA NA NA NA 19477 FUN_025979 17804 19953 5246 12307 3320 NA NA NA NA NA NA NA 19478 FUN_025978 3387 3199 738 2144 1416 NA NA NA NA NA NA NA 19479 FUN_009509 38 0 21 12 33 NA NA NA NA NA NA NA 19480 FUN_009336 14 0 24 26 135 ptg000004l:5454845-5455229 P25291 4.94e-22 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 19481 FUN_026777 0 0 14 0 14 NA NA NA NA NA NA NA 19482 FUN_026772 170 0 0 0 0 NA NA NA NA NA NA NA 19483 FUN_026773 0 0 0 0 13 NA NA NA NA NA NA NA 19484 FUN_026770 6 0 0 0 0 NA NA NA NA NA NA NA 19485 FUN_026771 46 0 0 0 0 NA NA NA NA NA NA NA 19486 FUN_026779 140 7 44 31 53 NA NA NA NA NA NA NA 19487 FUN_015572 160 51 7 48 66 NA NA NA NA NA NA NA 19488 FUN_015570 73 4 20 69 10 NA NA NA NA NA NA NA 19489 FUN_015576 13 8 0 10 0 NA NA NA NA NA NA NA 19490 FUN_015574 16 4 0 7 0 NA NA NA NA NA NA NA 19491 FUN_015575 0 0 0 1 15 NA NA NA NA NA NA NA 19492 FUN_022475 707 529 265 484 312 NA NA NA NA NA NA NA 19493 FUN_022474 443 375 139 402 315 NA NA NA NA NA NA NA 19494 FUN_022477 1786 1189 775 1478 823 NA NA NA NA NA NA NA 19495 FUN_022476 355 301 115 189 501 NA NA NA NA NA NA NA 19496 FUN_022471 557 605 235 485 329 NA NA NA NA NA NA NA 19497 FUN_022470 1086 964 345 315 427 NA NA NA NA NA NA NA 19498 FUN_022473 561 281 111 537 449 NA NA NA NA NA NA NA 19499 FUN_022472 442 350 108 310 187 NA NA NA NA NA NA NA 19500 FUN_022479 797 644 306 598 458 ptg000016l:9438769-9443667 P52624 3.24e-25 Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3) Mus musculus (Mouse) cellular response to glucose starvation [GO:0042149]; CMP catabolic process [GO:0006248]; dCMP catabolic process [GO:0006249]; dTMP catabolic process [GO:0046074]; dUMP catabolic process [GO:0046079]; pyrimidine nucleotide metabolic process [GO:0006220]; UMP catabolic process [GO:0046050]; UMP salvage [GO:0044206]; uridine catabolic process [GO:0006218]; uridine metabolic process [GO:0046108] GO:0004850; GO:0005654; GO:0005829; GO:0006218; GO:0006220; GO:0006248; GO:0006249; GO:0009032; GO:0042149; GO:0042802; GO:0044206; GO:0046050; GO:0046074; GO:0046079; GO:0046108; GO:0047847 19501 FUN_022478 630 790 450 863 1140 NA NA NA NA NA NA NA 19502 FUN_018620 15 0 0 12 0 NA NA NA NA NA NA NA 19503 FUN_018623 22 39 0 18 29 NA NA NA NA NA NA NA 19504 FUN_018622 0 0 3 0 12 NA NA NA NA NA NA NA 19505 FUN_018624 16 16 11 0 10 NA NA NA NA NA NA NA 19506 FUN_000594 2791 1382 1162 1625 1371 NA NA NA NA NA NA NA 19507 FUN_041549 5659 5256 3392 4573 3681 ptg000035l:5053711-5059135 Q01081 1.54e-21 Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005654; GO:0005681; GO:0006397; GO:0008380; GO:0015030; GO:0016607; GO:0030628; GO:0046872; GO:0050733; GO:0071013; GO:0089701 19508 FUN_041549 5659 5256 3392 4573 3681 ptg000035l:5053711-5059135 Q01081 1.54e-21 Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380] GO:0000398; GO:0003723; GO:0005654; GO:0005681; GO:0006397; GO:0008380; GO:0015030; GO:0016607; GO:0030628; GO:0046872; GO:0050733; GO:0071013; GO:0089701 19509 FUN_026602 146 266 272 251 163 ptg000020l:11418799-11421976 Q96AY4 1.09e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19510 FUN_026602 146 266 272 251 163 ptg000020l:11418799-11421976 Q96AY4 2.55e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19511 FUN_026602 146 266 272 251 163 ptg000020l:11418799-11421976 Q96AY4 5.45e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19512 FUN_026602 146 266 272 251 163 ptg000020l:11418799-11421976 Q96AY4 3.04e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19513 FUN_019267 0 0 0 7 0 NA NA NA NA NA NA NA 19514 FUN_041544 2881 2362 829 2303 1146 ptg000035l:4995814-5006547 Q9P289 2.28e-25 Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) Homo sapiens (Human) apoptotic process [GO:0006915]; cellular response to starvation [GO:0009267]; microvillus assembly [GO:0030033]; negative regulation of cell migration [GO:0030336]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of apoptotic process [GO:0042981]; regulation of hydrogen peroxide-induced cell death [GO:1903205]; response to hydrogen peroxide [GO:0042542] GO:0000287; GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0005794; GO:0005798; GO:0005829; GO:0006468; GO:0006915; GO:0009267; GO:0012506; GO:0016020; GO:0016324; GO:0030033; GO:0030336; GO:0042542; GO:0042802; GO:0042803; GO:0042981; GO:0046777; GO:0048471; GO:0070062; GO:0071944; GO:0106310; GO:1903205 19515 FUN_018992 17 0 0 0 0 NA NA NA NA NA NA NA 19516 FUN_018994 0 0 18 0 133 NA NA NA NA NA NA NA 19517 FUN_024738 0 0 0 35 42 NA NA NA NA NA NA NA 19518 FUN_019260 0 4 7 14 13 NA NA NA NA NA NA NA 19519 FUN_024730 0 0 0 0 74 NA NA NA NA NA NA NA 19520 FUN_024732 23 42 6 60 15 NA NA NA NA NA NA NA 19521 FUN_024733 0 0 0 36 32 NA NA NA NA NA NA NA 19522 FUN_024735 37 219 12 78 223 NA NA NA NA NA NA NA 19523 FUN_024736 3 29 0 16 36 NA NA NA NA NA NA NA 19524 FUN_024737 46 148 20 67 73 NA NA NA NA NA NA NA 19525 FUN_038018 2793 1324 1700 4159 2831 ptg000027l:1512552-1526671 Q69Z89 3.05e-44 Ras-associating and dilute domain-containing protein Mus musculus (Mouse) neural crest cell migration [GO:0001755]; signal transduction [GO:0007165]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0001755; GO:0005874; GO:0007165; GO:0032991; GO:0034446; GO:0051020 19526 FUN_038019 719 217 466 404 463 NA NA NA NA NA NA NA 19527 FUN_038010 969 658 628 1106 801 NA NA NA NA NA NA NA 19528 FUN_038011 1432 1127 527 788 1153 NA NA NA NA NA NA NA 19529 FUN_038012 2415 1518 1108 2191 1571 NA NA NA NA NA NA NA 19530 FUN_038013 6710 6252 2566 4276 3523 NA NA NA NA NA NA NA 19531 FUN_038014 19 17 11 0 21 NA NA NA NA NA NA NA 19532 FUN_038015 27 29 10 53 38 NA NA NA NA NA NA NA 19533 FUN_038016 597 670 547 652 402 NA NA NA NA NA NA NA 19534 FUN_038017 2730 1531 1513 2363 2234 NA NA NA NA NA NA NA 19535 FUN_021816 0 0 0 11 89 NA NA NA NA NA NA NA 19536 FUN_021817 6 4 26 54 35 NA NA NA NA NA NA NA 19537 FUN_021815 6 9 88 20 66 NA NA NA NA NA NA NA 19538 FUN_021812 0 0 17 0 11 NA NA NA NA NA NA NA 19539 FUN_021813 0 0 13 14 33 NA NA NA NA NA NA NA 19540 FUN_021810 0 0 0 0 12 NA NA NA NA NA NA NA 19541 FUN_021811 0 0 0 7 0 NA NA NA NA NA NA NA 19542 FUN_021818 15 0 15 0 15 NA NA NA NA NA NA NA 19543 FUN_021819 0 0 230 850 4 NA NA NA NA NA NA NA 19544 FUN_035279 1492 476 807 1195 859 NA NA NA NA NA NA NA 19545 FUN_020595 0 2 1 3 160 NA NA NA NA NA NA NA 19546 FUN_035273 3426 2936 3262 2567 2158 NA NA NA NA NA NA NA 19547 FUN_035272 762 242 333 748 527 NA NA NA NA NA NA NA 19548 FUN_035271 6330 3928 3002 4895 4322 ptg000025l:5867496-5882698 Q8R4C1 1.94e-29 Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2) Rattus norvegicus (Rat) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; mammary gland epithelium development [GO:0061180]; manganese ion transport [GO:0006828]; positive regulation of calcium ion import [GO:0090280]; protein localization to plasma membrane [GO:0072659] GO:0000139; GO:0005388; GO:0005524; GO:0005783; GO:0005886; GO:0006828; GO:0006874; GO:0009898; GO:0015662; GO:0016020; GO:0016323; GO:0016887; GO:0031410; GO:0032588; GO:0034220; GO:0046872; GO:0048471; GO:0061180; GO:0070588; GO:0072659; GO:0090280; GO:0140613 19549 FUN_035271 6330 3928 3002 4895 4322 ptg000025l:5867496-5882698 Q8R4C1 1.22e-26 Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2) Rattus norvegicus (Rat) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; mammary gland epithelium development [GO:0061180]; manganese ion transport [GO:0006828]; positive regulation of calcium ion import [GO:0090280]; protein localization to plasma membrane [GO:0072659] GO:0000139; GO:0005388; GO:0005524; GO:0005783; GO:0005886; GO:0006828; GO:0006874; GO:0009898; GO:0015662; GO:0016020; GO:0016323; GO:0016887; GO:0031410; GO:0032588; GO:0034220; GO:0046872; GO:0048471; GO:0061180; GO:0070588; GO:0072659; GO:0090280; GO:0140613 19550 FUN_035271 6330 3928 3002 4895 4322 ptg000025l:5867496-5882698 Q8R4C1 7.33e-26 Calcium-transporting ATPase type 2C member 2 (ATPase 2C2) (EC 7.2.2.10) (Ca(2+)/Mn(2+)-ATPase 2C2) (Secretory pathway Ca(2+)-transporting ATPase type 2) (SPCA2) Rattus norvegicus (Rat) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220]; mammary gland epithelium development [GO:0061180]; manganese ion transport [GO:0006828]; positive regulation of calcium ion import [GO:0090280]; protein localization to plasma membrane [GO:0072659] GO:0000139; GO:0005388; GO:0005524; GO:0005783; GO:0005886; GO:0006828; GO:0006874; GO:0009898; GO:0015662; GO:0016020; GO:0016323; GO:0016887; GO:0031410; GO:0032588; GO:0034220; GO:0046872; GO:0048471; GO:0061180; GO:0070588; GO:0072659; GO:0090280; GO:0140613 19551 FUN_035270 1143 667 411 656 487 ptg000025l:5862341-5863844 Q32KI9 0 Arylsulfatase I (ASI) (EC 3.1.6.-) Mus musculus (Mouse) NA GO:0005576; GO:0005783; GO:0008484; GO:0046872 19552 FUN_035276 2686 1224 1305 1787 1732 NA NA NA NA NA NA NA 19553 FUN_035275 1684 2498 1056 1367 808 NA NA NA NA NA NA NA 19554 FUN_035274 4275 3049 1862 3386 2599 ptg000025l:5918813-5923872 Q6PGV1 1.5e-40 V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (Vacuolar proton pump subunit d 1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; cilium assembly [GO:0060271]; eye pigment granule organization [GO:0008057]; heart looping [GO:0001947]; left/right axis specification [GO:0070986]; melanosome organization [GO:0032438]; neuromast hair cell development [GO:0035675]; pronephric duct development [GO:0039022]; response to copper ion [GO:0046688]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; vacuolar acidification [GO:0007035]; vacuolar transport [GO:0007034] GO:0001947; GO:0003406; GO:0005765; GO:0005769; GO:0006879; GO:0007034; GO:0007035; GO:0008057; GO:0016471; GO:0032438; GO:0033179; GO:0033181; GO:0035675; GO:0036295; GO:0039022; GO:0046688; GO:0046961; GO:0060041; GO:0060271; GO:0070986 19555 FUN_035274 4275 3049 1862 3386 2599 ptg000025l:5918813-5923872 Q6PGV1 1.5e-40 V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (Vacuolar proton pump subunit d 1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; cilium assembly [GO:0060271]; eye pigment granule organization [GO:0008057]; heart looping [GO:0001947]; left/right axis specification [GO:0070986]; melanosome organization [GO:0032438]; neuromast hair cell development [GO:0035675]; pronephric duct development [GO:0039022]; response to copper ion [GO:0046688]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; vacuolar acidification [GO:0007035]; vacuolar transport [GO:0007034] GO:0001947; GO:0003406; GO:0005765; GO:0005769; GO:0006879; GO:0007034; GO:0007035; GO:0008057; GO:0016471; GO:0032438; GO:0033179; GO:0033181; GO:0035675; GO:0036295; GO:0039022; GO:0046688; GO:0046961; GO:0060041; GO:0060271; GO:0070986 19556 FUN_035274 4275 3049 1862 3386 2599 ptg000025l:5918813-5923872 Q6PGV1 1.5e-40 V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (Vacuolar proton pump subunit d 1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; cilium assembly [GO:0060271]; eye pigment granule organization [GO:0008057]; heart looping [GO:0001947]; left/right axis specification [GO:0070986]; melanosome organization [GO:0032438]; neuromast hair cell development [GO:0035675]; pronephric duct development [GO:0039022]; response to copper ion [GO:0046688]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; vacuolar acidification [GO:0007035]; vacuolar transport [GO:0007034] GO:0001947; GO:0003406; GO:0005765; GO:0005769; GO:0006879; GO:0007034; GO:0007035; GO:0008057; GO:0016471; GO:0032438; GO:0033179; GO:0033181; GO:0035675; GO:0036295; GO:0039022; GO:0046688; GO:0046961; GO:0060041; GO:0060271; GO:0070986 19557 FUN_035274 4275 3049 1862 3386 2599 ptg000025l:5918813-5923872 Q6PGV1 7.19e-25 V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (Vacuolar proton pump subunit d 1) Danio rerio (Zebrafish) (Brachydanio rerio) cellular iron ion homeostasis [GO:0006879]; cellular response to increased oxygen levels [GO:0036295]; cilium assembly [GO:0060271]; eye pigment granule organization [GO:0008057]; heart looping [GO:0001947]; left/right axis specification [GO:0070986]; melanosome organization [GO:0032438]; neuromast hair cell development [GO:0035675]; pronephric duct development [GO:0039022]; response to copper ion [GO:0046688]; retina development in camera-type eye [GO:0060041]; retinal pigment epithelium development [GO:0003406]; vacuolar acidification [GO:0007035]; vacuolar transport [GO:0007034] GO:0001947; GO:0003406; GO:0005765; GO:0005769; GO:0006879; GO:0007034; GO:0007035; GO:0008057; GO:0016471; GO:0032438; GO:0033179; GO:0033181; GO:0035675; GO:0036295; GO:0039022; GO:0046688; GO:0046961; GO:0060041; GO:0060271; GO:0070986 19558 FUN_031198 0 35 0 0 4 NA NA NA NA NA NA NA 19559 FUN_031199 4953 4743 4730 2754 2180 ptg000023l:17821348-17920350 P14381 9.01e-76 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 19560 FUN_031199 4953 4743 4730 2754 2180 ptg000023l:17821348-17920350 P14381 9.01e-76 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 19561 FUN_039624 0 0 9 0 21 NA NA NA NA NA NA NA 19562 FUN_002523 3665 132 192 424 214 NA NA NA NA NA NA NA 19563 FUN_031191 214 239 80 196 73 NA NA NA NA NA NA NA 19564 FUN_031196 95 0 42 41 40 NA NA NA NA NA NA NA 19565 FUN_031197 102 54 130 103 100 NA NA NA NA NA NA NA 19566 FUN_039766 0 0 0 0 6 NA NA NA NA NA NA NA 19567 FUN_030579 0 0 0 0 9 ptg000023l:11667932-11673174 P84239 1.63e-81 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19568 FUN_030579 0 0 0 0 9 ptg000023l:11667932-11673174 P84239 9.05e-81 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19569 FUN_030571 0 0 0 0 10 NA NA NA NA NA NA NA 19570 FUN_031228 36 18 7 10 25 ptg000023l:18247743-18248869 B8VIU6 2.22e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 19571 FUN_031224 0 0 0 18 0 NA NA NA NA NA NA NA 19572 FUN_031227 28 110 87 85 168 NA NA NA NA NA NA NA 19573 FUN_031220 111 203 63 111 86 NA NA NA NA NA NA NA 19574 FUN_031221 7178 3462 3474 7702 6007 NA NA NA NA NA NA NA 19575 FUN_031222 13 0 33 0 111 NA NA NA NA NA NA NA 19576 FUN_027419 0 56 0 0 0 NA NA NA NA NA NA NA 19577 FUN_027410 2 0 120 0 14 NA NA NA NA NA NA NA 19578 FUN_027412 48 10 11 11 27 NA NA NA NA NA NA NA 19579 FUN_027413 3 19 6 8 19 NA NA NA NA NA NA NA 19580 FUN_027414 52 13 45 35 30 NA NA NA NA NA NA NA 19581 FUN_027415 0 0 0 0 22 NA NA NA NA NA NA NA 19582 FUN_029401 2866 1991 1610 2776 1268 NA NA NA NA NA NA NA 19583 FUN_029400 1923 5780 4807 2774 1634 NA NA NA NA NA NA NA 19584 FUN_029403 511 314 496 398 423 NA NA NA NA NA NA NA 19585 FUN_029405 4720 3363 2431 3473 3464 NA NA NA NA NA NA NA 19586 FUN_029404 2282 1288 982 1546 1245 NA NA NA NA NA NA NA 19587 FUN_006199 296 1767 281 1067 1088 NA NA NA NA NA NA NA 19588 FUN_029407 3 18 23 12 35 ptg000023l:1565749-1566160 P84239 1.08e-95 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19589 FUN_006190 7 0 0 0 0 NA NA NA NA NA NA NA 19590 FUN_006191 0 46 0 10 98 NA NA NA NA NA NA NA 19591 FUN_006192 5630 7135 4061 4088 2719 NA NA NA NA NA NA NA 19592 FUN_006193 0 9 0 0 0 NA NA NA NA NA NA NA 19593 FUN_006195 14 8 13 30 17 NA NA NA NA NA NA NA 19594 FUN_006196 7112 8247 5252 5075 3329 NA NA NA NA NA NA NA 19595 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 2.63e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19596 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 6.67e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19597 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 2.1e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19598 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 2.56e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19599 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 2.72e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19600 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 4.39e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19601 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 5.07e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19602 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 1.27e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19603 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 1.2e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19604 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 1.45e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19605 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 1.7e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19606 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 1.08e-37 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19607 FUN_037103 176 64 42 92 171 ptg000026l:5780833-5838676 P0CI65 1.08e-37 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19608 FUN_037100 299 13 180 252 142 ptg000026l:5762391-5767040 A0JM23 5.43e-38 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 19609 FUN_037100 299 13 180 252 142 ptg000026l:5762391-5767040 A0JM23 6.48e-35 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 19610 FUN_037100 299 13 180 252 142 ptg000026l:5762391-5767040 A0JM23 1.5e-34 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 19611 FUN_037107 381 65 0 166 382 NA NA NA NA NA NA NA 19612 FUN_037106 786 769 338 734 822 ptg000026l:5881885-5892401 P0CI65 1.09e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19613 FUN_037106 786 769 338 734 822 ptg000026l:5881885-5892401 P0CI65 1.08e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19614 FUN_037106 786 769 338 734 822 ptg000026l:5881885-5892401 P0CI65 9.28e-47 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19615 FUN_037106 786 769 338 734 822 ptg000026l:5881885-5892401 P0CI65 1.74e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19616 FUN_037106 786 769 338 734 822 ptg000026l:5881885-5892401 P0CI65 1.96e-44 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19617 FUN_037106 786 769 338 734 822 ptg000026l:5881885-5892401 P0CI65 2.83e-34 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19618 FUN_037105 32 0 30 43 91 NA NA NA NA NA NA NA 19619 FUN_037104 777 479 42 248 149 ptg000026l:5843760-5850043 P0CI65 5.93e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19620 FUN_037104 777 479 42 248 149 ptg000026l:5843760-5850043 P0CI65 2.9e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 19621 FUN_037109 113 0 2 0 2 NA NA NA NA NA NA NA 19622 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 3.03e-50 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19623 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 4.13e-47 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19624 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 4.49e-47 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19625 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 4.73e-47 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19626 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 1.82e-45 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19627 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 3.03e-44 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19628 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 9.94e-43 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19629 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 2.34e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19630 FUN_037108 321 11 12 174 99 ptg000026l:5914565-5919897 Q7Z494 1.1e-35 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 19631 FUN_032559 193 53 7 103 17 ptg000023l:33187459-33190512 Q8AWC7 5.65e-22 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Gallus gallus (Chicken) fucosylation [GO:0036065]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0036065; GO:0046920 19632 FUN_032553 14 0 0 0 0 NA NA NA NA NA NA NA 19633 FUN_032552 1317 11 6 13 11 ptg000023l:33136915-33138028 Q8AWC7 1.53e-25 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Gallus gallus (Chicken) fucosylation [GO:0036065]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0036065; GO:0046920 19634 FUN_032550 470 5 0 0 5 NA NA NA NA NA NA NA 19635 FUN_032557 101 24 0 44 16 ptg000023l:33178569-33183478 Q70AG8 1.35e-21 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0046920 19636 FUN_032555 196 49 3 17 10 ptg000023l:33158317-33163392 Q8HYJ7 2.95e-21 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 19637 FUN_005087 183 842 852 2825 418 ntLink_8:30946013-30950478 Q95P04 1.3e-40 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 19638 FUN_005087 183 842 852 2825 418 ntLink_8:30946013-30950478 Q95P04 1.42e-39 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 19639 FUN_005086 8 13 0 64 4 NA NA NA NA NA NA NA 19640 FUN_005085 98 105 20 107 30 NA NA NA NA NA NA NA 19641 FUN_005084 21 0 4 13 2 NA NA NA NA NA NA NA 19642 FUN_005083 670 1980 1723 5030 546 ntLink_8:30920670-30925165 Q95P04 2.38e-40 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 19643 FUN_005083 670 1980 1723 5030 546 ntLink_8:30920670-30925165 Q95P04 1.43e-39 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 19644 FUN_005080 71 168 144 377 90 ntLink_8:30911222-30914454 Q95P04 6.82e-40 GFP-like non-fluorescent chromoprotein (gtCP) Goniopora tenuidens (Anemone coral) (Rhodaraea tenuidens) bioluminescence [GO:0008218] GO:0008218 19645 FUN_005089 1 0 0 6 0 NA NA NA NA NA NA NA 19646 FUN_042937 78 155 90 0 310 NA NA NA NA NA NA NA 19647 FUN_042934 226 468 302 4 117 NA NA NA NA NA NA NA 19648 FUN_016615 263 230 214 310 326 NA NA NA NA NA NA NA 19649 FUN_016612 290 327 53 248 225 NA NA NA NA NA NA NA 19650 FUN_042933 17 0 3 3 0 NA NA NA NA NA NA NA 19651 FUN_032889 139 78 24 38 46 NA NA NA NA NA NA NA 19652 FUN_032885 341 33 123 194 87 NA NA NA NA NA NA NA 19653 FUN_032884 113 461 68 81 62 NA NA NA NA NA NA NA 19654 FUN_016611 1013 605 484 1360 891 NA NA NA NA NA NA NA 19655 FUN_032881 0 0 0 15 0 NA NA NA NA NA NA NA 19656 FUN_032883 457 1013 511 658 153 NA NA NA NA NA NA NA 19657 FUN_032882 194 550 166 214 143 NA NA NA NA NA NA NA 19658 FUN_034487 2637 1799 1050 3238 2151 NA NA NA NA NA NA NA 19659 FUN_034486 1697 1273 733 1947 1546 ptg000024l:9241982-9266327 Q9Z2C5 1.11e-22 Myotubularin (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; endosome to lysosome transport [GO:0008333]; intermediate filament organization [GO:0045109]; mitochondrion distribution [GO:0048311]; mitochondrion morphogenesis [GO:0070584]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of skeletal muscle tissue growth [GO:0048633]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein transport [GO:0015031]; regulation of vacuole organization [GO:0044088]; skeletal muscle tissue growth [GO:0048630]; TOR signaling [GO:0031929] GO:0000045; GO:0001726; GO:0004438; GO:0004721; GO:0005737; GO:0005770; GO:0005829; GO:0005886; GO:0006470; GO:0008333; GO:0015031; GO:0019215; GO:0030175; GO:0031674; GO:0031929; GO:0032007; GO:0032435; GO:0035091; GO:0043161; GO:0043491; GO:0044088; GO:0045109; GO:0046716; GO:0046856; GO:0048311; GO:0048630; GO:0048633; GO:0051898; GO:0052629; GO:0070584; GO:1902902 19660 FUN_034486 1697 1273 733 1947 1546 ptg000024l:9241982-9266327 Q9Z2C5 1.11e-22 Myotubularin (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Mus musculus (Mouse) autophagosome assembly [GO:0000045]; endosome to lysosome transport [GO:0008333]; intermediate filament organization [GO:0045109]; mitochondrion distribution [GO:0048311]; mitochondrion morphogenesis [GO:0070584]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of TOR signaling [GO:0032007]; phosphatidylinositol dephosphorylation [GO:0046856]; positive regulation of skeletal muscle tissue growth [GO:0048633]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein dephosphorylation [GO:0006470]; protein kinase B signaling [GO:0043491]; protein transport [GO:0015031]; regulation of vacuole organization [GO:0044088]; skeletal muscle tissue growth [GO:0048630]; TOR signaling [GO:0031929] GO:0000045; GO:0001726; GO:0004438; GO:0004721; GO:0005737; GO:0005770; GO:0005829; GO:0005886; GO:0006470; GO:0008333; GO:0015031; GO:0019215; GO:0030175; GO:0031674; GO:0031929; GO:0032007; GO:0032435; GO:0035091; GO:0043161; GO:0043491; GO:0044088; GO:0045109; GO:0046716; GO:0046856; GO:0048311; GO:0048630; GO:0048633; GO:0051898; GO:0052629; GO:0070584; GO:1902902 19661 FUN_034485 13503 8914 8453 16025 8338 ptg000024l:9235707-9240603 Q8BQS5 2.95e-43 Adiponectin receptor protein 2 (Progestin and adipoQ receptor family member 2) (Progestin and adipoQ receptor family member II) Mus musculus (Mouse) adiponectin-activated signaling pathway [GO:0033211]; cellular response to fatty acid [GO:0071398]; fatty acid oxidation [GO:0019395]; female pregnancy [GO:0007565]; glucose homeostasis [GO:0042593]; heart development [GO:0007507]; hormone-mediated signaling pathway [GO:0009755]; negative regulation of cell growth [GO:0030308]; negative regulation of gene expression [GO:0010629]; negative regulation of hepatic stellate cell migration [GO:0061871]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of glucose import [GO:0046326]; positive regulation of protein phosphorylation [GO:0001934]; response to amine [GO:0014075]; response to ethanol [GO:0045471]; response to fructose [GO:0009750]; response to lipopolysaccharide [GO:0032496]; response to nutrient [GO:0007584]; response to xenobiotic stimulus [GO:0009410]; vascular wound healing [GO:0061042] GO:0001934; GO:0005886; GO:0007507; GO:0007565; GO:0007584; GO:0009410; GO:0009750; GO:0009755; GO:0010629; GO:0014075; GO:0019395; GO:0030308; GO:0032496; GO:0033211; GO:0038023; GO:0042593; GO:0042802; GO:0045471; GO:0046326; GO:0046872; GO:0055100; GO:0061042; GO:0061871; GO:0071398; GO:0097003; GO:0120162 19662 FUN_034484 1498 1437 837 1547 1152 NA NA NA NA NA NA NA 19663 FUN_034483 1113 704 494 767 557 ptg000024l:9211403-9218053 Q0P595 4.94e-27 NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7) Bos taurus (Bovine) DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; histone H3 deacetylation [GO:0070932]; homologous chromosome pairing at meiosis [GO:0007129]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transposition [GO:0010529]; osteoblast differentiation [GO:0001649]; positive regulation of rRNA processing [GO:2000234]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription involved in exit from mitosis [GO:0007072]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein depropionylation [GO:0106230]; R-loop processing [GO:0062176]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of gluconeogenesis [GO:0006111]; regulation of mitochondrion organization [GO:0010821]; regulation of protein export from nucleus [GO:0046825]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of transcription of nucleolar large rRNA by RNA polymerase I [GO:1901836]; rRNA transcription [GO:0009303] GO:0000122; GO:0000785; GO:0001649; GO:0003682; GO:0003714; GO:0004407; GO:0005634; GO:0005730; GO:0005731; GO:0005737; GO:0006111; GO:0006281; GO:0006357; GO:0006476; GO:0007072; GO:0007129; GO:0009303; GO:0010529; GO:0010821; GO:0016607; GO:0019213; GO:0031397; GO:0034979; GO:0035861; GO:0036055; GO:0045943; GO:0046825; GO:0046872; GO:0061697; GO:0061698; GO:0062176; GO:0070403; GO:0070932; GO:0097372; GO:0106230; GO:0106231; GO:0140861; GO:1901836; GO:2000234; GO:2001032 19664 FUN_034482 58 0 33 10 102 NA NA NA NA NA NA NA 19665 FUN_034481 7793 2769 3040 3944 2547 NA NA NA NA NA NA NA 19666 FUN_034480 809 523 307 325 385 NA NA NA NA NA NA NA 19667 FUN_016619 1059 1137 553 662 421 NA NA NA NA NA NA NA 19668 FUN_034489 1000 696 619 1197 1027 NA NA NA NA NA NA NA 19669 FUN_034488 336 406 256 453 470 ptg000024l:9280903-9283450 Q3B8H4 6.22e-27 Rhombotin-1 (LIM domain only protein 1) (LMO-1) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0046872 19670 FUN_041829 231 258 111 146 325 NA NA NA NA NA NA NA 19671 FUN_041828 1687 1128 812 1305 1364 NA NA NA NA NA NA NA 19672 FUN_041825 2076 3612 2104 2782 1693 NA NA NA NA NA NA NA 19673 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 5.61e-44 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19674 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 5.61e-44 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19675 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 5.24e-37 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19676 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 2.69e-31 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19677 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 2.05e-30 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19678 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 6.57e-30 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19679 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 6.58e-27 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19680 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 9.04e-24 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19681 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 1.15e-22 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19682 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 4.89e-22 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19683 FUN_041824 4533 3095 2628 4023 3476 ptg000035l:8013157-8051737 P0C6F1 8.6e-21 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) Mus musculus (Mouse) cilium movement [GO:0003341]; cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005858; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19684 FUN_041827 698 502 299 516 390 NA NA NA NA NA NA NA 19685 FUN_041826 2330 2153 2191 2051 1252 NA NA NA NA NA NA NA 19686 FUN_041821 1016 1093 310 921 574 ptg000035l:7984000-7986899 P42325 1.53e-31 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 19687 FUN_041821 1016 1093 310 921 574 ptg000035l:7984000-7986899 P42325 1.59e-21 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 19688 FUN_041820 534 210 227 515 523 ptg000035l:7969895-7976343 O42122 1.23e-26 Protein Wnt-5b Oryzias latipes (Japanese rice fish) (Japanese killifish) animal organ development [GO:0048513]; canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; muscle cell differentiation [GO:0042692]; neuron differentiation [GO:0030182]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052] GO:0005109; GO:0005125; GO:0005615; GO:0030182; GO:0042692; GO:0045165; GO:0048513; GO:0060070; GO:1904105; GO:2000052 19689 FUN_041823 566 238 134 439 449 ptg000035l:7992876-8012593 Q9P225 6.19e-24 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19690 FUN_041823 566 238 134 439 449 ptg000035l:7992876-8012593 Q9P225 1.22e-22 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19691 FUN_041823 566 238 134 439 449 ptg000035l:7992876-8012593 Q9P225 1.22e-22 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19692 FUN_041823 566 238 134 439 449 ptg000035l:7992876-8012593 Q9P225 5.22e-21 Dynein axonemal heavy chain 2 (Axonemal beta dynein heavy chain 2) (Ciliary dynein heavy chain 2) (Dynein heavy chain domain-containing protein 3) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; inner dynein arm assembly [GO:0036159]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0031514; GO:0036126; GO:0036156; GO:0036159; GO:0045505; GO:0051959; GO:0060285 19693 FUN_041822 6907 4482 3822 6777 7419 NA NA NA NA NA NA NA 19694 FUN_033688 773 469 358 596 749 NA NA NA NA NA NA NA 19695 FUN_033689 724 1527 131 715 170 ptg000024l:340690-352086 P0CT40 2.37e-29 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 19696 FUN_033689 724 1527 131 715 170 ptg000024l:340690-352086 P0CT40 2.37e-29 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 19697 FUN_001351 1975 1785 823 2390 1982 NA NA NA NA NA NA NA 19698 FUN_001350 700 315 563 925 745 NA NA NA NA NA NA NA 19699 FUN_001357 1784 135 397 871 2588 NA NA NA NA NA NA NA 19700 FUN_001356 589 531 533 591 930 ntLink_6:11462019-11471489 O06837 4.02e-26 Phenylacetaldehyde dehydrogenase (PAD) (EC 1.2.1.39) Pseudomonas fluorescens styrene catabolic process [GO:0042207] GO:0008957; GO:0042207 19701 FUN_001355 1704 473 629 1117 414 ntLink_6:11439202-11454787 P21328 9.15e-34 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19702 FUN_001354 2096 1102 970 1613 1146 NA NA NA NA NA NA NA 19703 FUN_033680 0 38 41 5 3 NA NA NA NA NA NA NA 19704 FUN_033681 3575 1242 1273 2574 3093 NA NA NA NA NA NA NA 19705 FUN_001359 640 10 346 679 404 NA NA NA NA NA NA NA 19706 FUN_001358 84 0 5 23 55 NA NA NA NA NA NA NA 19707 FUN_033684 810 457 233 455 318 NA NA NA NA NA NA NA 19708 FUN_033685 0 0 0 0 22 NA NA NA NA NA NA NA 19709 FUN_033686 20 20 35 0 41 NA NA NA NA NA NA NA 19710 FUN_033687 2297 1279 1103 1222 1563 ptg000024l:318495-329963 P48441 1.89e-38 Alpha-L-iduronidase (EC 3.2.1.76) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; bone development [GO:0060348]; carbohydrate metabolic process [GO:0005975]; cartilage homeostasis [GO:1990079]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; memory [GO:0007613]; negative regulation of cartilage development [GO:0061037]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; positive regulation of bone resorption [GO:0045780]; positive regulation of collagen catabolic process [GO:0120158]; skeletal system morphogenesis [GO:0048705]; visual learning [GO:0008542] GO:0000902; GO:0003940; GO:0004553; GO:0005102; GO:0005615; GO:0005764; GO:0005975; GO:0006027; GO:0007040; GO:0007613; GO:0007626; GO:0007628; GO:0008344; GO:0008542; GO:0030135; GO:0030198; GO:0030200; GO:0030209; GO:0030211; GO:0035108; GO:0043202; GO:0045780; GO:0048705; GO:0048878; GO:0060348; GO:0061037; GO:0090341; GO:0120158; GO:1990079 19711 FUN_033687 2297 1279 1103 1222 1563 ptg000024l:318495-329963 P48441 3.8e-31 Alpha-L-iduronidase (EC 3.2.1.76) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; bone development [GO:0060348]; carbohydrate metabolic process [GO:0005975]; cartilage homeostasis [GO:1990079]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; memory [GO:0007613]; negative regulation of cartilage development [GO:0061037]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; positive regulation of bone resorption [GO:0045780]; positive regulation of collagen catabolic process [GO:0120158]; skeletal system morphogenesis [GO:0048705]; visual learning [GO:0008542] GO:0000902; GO:0003940; GO:0004553; GO:0005102; GO:0005615; GO:0005764; GO:0005975; GO:0006027; GO:0007040; GO:0007613; GO:0007626; GO:0007628; GO:0008344; GO:0008542; GO:0030135; GO:0030198; GO:0030200; GO:0030209; GO:0030211; GO:0035108; GO:0043202; GO:0045780; GO:0048705; GO:0048878; GO:0060348; GO:0061037; GO:0090341; GO:0120158; GO:1990079 19712 FUN_033687 2297 1279 1103 1222 1563 ptg000024l:318495-329963 P48441 2.82e-29 Alpha-L-iduronidase (EC 3.2.1.76) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; adult walking behavior [GO:0007628]; bone development [GO:0060348]; carbohydrate metabolic process [GO:0005975]; cartilage homeostasis [GO:1990079]; cell morphogenesis [GO:0000902]; chemical homeostasis [GO:0048878]; dermatan sulfate catabolic process [GO:0030209]; extracellular matrix organization [GO:0030198]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200]; heparin catabolic process [GO:0030211]; limb morphogenesis [GO:0035108]; locomotory behavior [GO:0007626]; lysosome organization [GO:0007040]; memory [GO:0007613]; negative regulation of cartilage development [GO:0061037]; negative regulation of secretion of lysosomal enzymes [GO:0090341]; positive regulation of bone resorption [GO:0045780]; positive regulation of collagen catabolic process [GO:0120158]; skeletal system morphogenesis [GO:0048705]; visual learning [GO:0008542] GO:0000902; GO:0003940; GO:0004553; GO:0005102; GO:0005615; GO:0005764; GO:0005975; GO:0006027; GO:0007040; GO:0007613; GO:0007626; GO:0007628; GO:0008344; GO:0008542; GO:0030135; GO:0030198; GO:0030200; GO:0030209; GO:0030211; GO:0035108; GO:0043202; GO:0045780; GO:0048705; GO:0048878; GO:0060348; GO:0061037; GO:0090341; GO:0120158; GO:1990079 19713 FUN_040725 88 52 70 58 123 ptg000031l:12479463-12480324 Q12950 5.54e-39 Forkhead box protein D4 (Forkhead-related protein FKHL9) (Forkhead-related transcription factor 5) (FREAC-5) (Myeloid factor-alpha) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008301; GO:0009653; GO:0030154; GO:0043565 19714 FUN_002618 0 0 21 25 57 NA NA NA NA NA NA NA 19715 FUN_040724 6 0 9 2 8 NA NA NA NA NA NA NA 19716 FUN_002613 86 38 163 41 50 NA NA NA NA NA NA NA 19717 FUN_002611 1 44 331 14 10 NA NA NA NA NA NA NA 19718 FUN_002617 3 3 7 0 21 NA NA NA NA NA NA NA 19719 FUN_002616 10 227 150 58 1462 NA NA NA NA NA NA NA 19720 FUN_002615 162 303 358 40 508 NA NA NA NA NA NA NA 19721 FUN_002614 7 14 26 27 16 NA NA NA NA NA NA NA 19722 FUN_011106 0 0 16 12 0 NA NA NA NA NA NA NA 19723 FUN_011105 12 0 0 11 0 NA NA NA NA NA NA NA 19724 FUN_040726 4 25 0 0 0 NA NA NA NA NA NA NA 19725 FUN_011102 0 0 0 7 0 NA NA NA NA NA NA NA 19726 FUN_019408 0 0 0 3 6 NA NA NA NA NA NA NA 19727 FUN_040720 6 14 0 11 0 ptg000031l:12397406-12398275 Q0IH87 1.36e-43 Paired box protein Pax-3-B (xPax3-B) (Paired-domain transcription factor Pax3-B) Xenopus laevis (African clawed frog) fibroblast growth factor receptor signaling pathway [GO:0008543]; hatching gland development [GO:0048785]; nervous system development [GO:0007399]; neural crest cell fate commitment [GO:0014034]; neural crest formation [GO:0014029]; positive regulation of DNA-templated transcription [GO:0045893]; Wnt signaling pathway [GO:0016055] GO:0000981; GO:0003677; GO:0005634; GO:0007399; GO:0008543; GO:0014029; GO:0014034; GO:0016055; GO:0045893; GO:0048785 19728 FUN_040722 426 288 185 157 151 ptg000031l:12415944-12417175 P55166 1.28e-46 Paired box protein Pax-9 Gallus gallus (Chicken) anatomical structure development [GO:0048856]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0048856 19729 FUN_031622 0 75 94 0 11 NA NA NA NA NA NA NA 19730 FUN_012745 11 0 10 2 14 NA NA NA NA NA NA NA 19731 FUN_029465 0 360 152 36 34 NA NA NA NA NA NA NA 19732 FUN_006979 3046 1746 2161 3312 2987 ptg000001l:18953518-18992970 Q8UUZ1 5.12e-119 Protein mab-21-like 2 Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; closure of optic fissure [GO:0061386]; cornea development in camera-type eye [GO:0061303]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic eye morphogenesis [GO:0048048]; enteric nervous system development [GO:0048484]; eye development [GO:0001654]; lens development in camera-type eye [GO:0002088]; lens morphogenesis in camera-type eye [GO:0002089]; retina development in camera-type eye [GO:0060041] GO:0001654; GO:0002088; GO:0002089; GO:0005634; GO:0005737; GO:0043010; GO:0048048; GO:0048484; GO:0048701; GO:0060041; GO:0061303; GO:0061386 19733 FUN_029463 198 6 64 74 85 NA NA NA NA NA NA NA 19734 FUN_029462 0 481 0 5 3 NA NA NA NA NA NA NA 19735 FUN_012742 13 0 9 42 12 NA NA NA NA NA NA NA 19736 FUN_029460 1 84 53 149 18 NA NA NA NA NA NA NA 19737 FUN_006972 96 8 12 31 698 NA NA NA NA NA NA NA 19738 FUN_006973 30 27 60 34 327 NA NA NA NA NA NA NA 19739 FUN_006970 25 0 0 37 15 NA NA NA NA NA NA NA 19740 FUN_006971 19 0 0 20 66 ptg000001l:18877300-18878775 Q9U6Y6 1.52e-26 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 19741 FUN_012748 0 9 0 0 0 NA NA NA NA NA NA NA 19742 FUN_006977 1097 1131 472 614 384 NA NA NA NA NA NA NA 19743 FUN_029469 12 2613 98 316 274 NA NA NA NA NA NA NA 19744 FUN_029468 195 1065 786 975 85 NA NA NA NA NA NA NA 19745 FUN_016454 2605 1074 1182 1766 1758 NA NA NA NA NA NA NA 19746 FUN_016455 1765 1963 487 14 531 NA NA NA NA NA NA NA 19747 FUN_016456 19 1284 933 9 1919 ptg000011l:3284525-3285026 Q9I9M5 5.69e-46 Frizzled-1 (Fz-1) (Xfz1) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 19748 FUN_016457 2809 1496 4 3491 1101 ptg000011l:3288147-3288501 Q9I9M5 6.09e-32 Frizzled-1 (Fz-1) (Xfz1) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 19749 FUN_016450 15 0 13 44 21 ptg000011l:3220532-3233078 Q8NFF2 9.73e-26 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Homo sapiens (Human) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; enamel mineralization [GO:0070166]; ion transport [GO:0006811]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to high light intensity [GO:0009644]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005516; GO:0005737; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0009644; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070166; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 19750 FUN_016451 62 94 50 59 118 NA NA NA NA NA NA NA 19751 FUN_016452 665 780 369 678 575 NA NA NA NA NA NA NA 19752 FUN_016453 2217 1413 1208 1589 1059 NA NA NA NA NA NA NA 19753 FUN_016458 1009 597 457 1340 702 ptg000011l:3293366-3295019 Q9I9M5 0 Frizzled-1 (Fz-1) (Xfz1) Xenopus laevis (African clawed frog) Wnt signaling pathway [GO:0016055] GO:0004930; GO:0005886; GO:0016055 19754 FUN_016459 6 57 65 33 163 NA NA NA NA NA NA NA 19755 FUN_043535 1855 2304 1036 1163 1045 NA NA NA NA NA NA NA 19756 FUN_043534 446 115 92 155 111 NA NA NA NA NA NA NA 19757 FUN_043537 34 11 73 62 62 NA NA NA NA NA NA NA 19758 FUN_043531 1463 1032 700 1003 765 NA NA NA NA NA NA NA 19759 FUN_043530 4906 4134 3007 3567 2381 NA NA NA NA NA NA NA 19760 FUN_043533 1020 1082 708 1177 1379 NA NA NA NA NA NA NA 19761 FUN_043532 4890 3680 2835 4289 3652 NA NA NA NA NA NA NA 19762 FUN_043539 2058 1093 1128 1130 1343 NA NA NA NA NA NA NA 19763 FUN_040714 20570 14736 10541 10751 4875 ptg000031l:12308451-12310096 A1L3F4 1.16e-78 RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) Xenopus laevis (African clawed frog) NA GO:0000932; GO:0003723; GO:0005634; GO:0046872 19764 FUN_040714 20570 14736 10541 10751 4875 ptg000031l:12308451-12310096 A1L3F4 1.16e-78 RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) Xenopus laevis (African clawed frog) NA GO:0000932; GO:0003723; GO:0005634; GO:0046872 19765 FUN_003223 36 7 4 57 78 NA NA NA NA NA NA NA 19766 FUN_022435 2736 2217 1035 2285 2281 NA NA NA NA NA NA NA 19767 FUN_040715 1414 1318 640 1541 1233 NA NA NA NA NA NA NA 19768 FUN_008225 9 36 29 37 20 ptg000002l:9470279-9472676 Q8AXN9 7.51e-28 Retinoid isomerohydrolase (EC 3.1.1.64) (All-trans-retinyl-palmitate hydrolase) (Lutein isomerase) (Meso-zeaxanthin isomerase) (EC 5.3.3.22) (Retinal pigment epithelium-specific 65 kDa protein) (Retinol isomerase) Cynops pyrrhogaster (Japanese fire-bellied newt) (Molge pyrrhogaster) response to stimulus [GO:0050896]; retinoid metabolic process [GO:0001523]; visual perception [GO:0007601]; zeaxanthin biosynthetic process [GO:1901827] GO:0001523; GO:0001786; GO:0005789; GO:0005886; GO:0007601; GO:0016020; GO:0016702; GO:0016853; GO:0031210; GO:0046872; GO:0050896; GO:0052884; GO:0052885; GO:1901612; GO:1901827 19769 FUN_028735 0 5 0 6 0 NA NA NA NA NA NA NA 19770 FUN_028730 55 70 42 29 48 ptg000022l:3249378-3257086 Q96AY4 1.71e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19771 FUN_028730 55 70 42 29 48 ptg000022l:3249378-3257086 Q96AY4 1.24e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19772 FUN_028730 55 70 42 29 48 ptg000022l:3249378-3257086 Q96AY4 5.27e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19773 FUN_028730 55 70 42 29 48 ptg000022l:3249378-3257086 Q96AY4 3.39e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19774 FUN_010519 1889 1029 878 2123 974 NA NA NA NA NA NA NA 19775 FUN_028732 0 38 21 12 32 NA NA NA NA NA NA NA 19776 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 1.65e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19777 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 2.24e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19778 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 1.75e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19779 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 2.89e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19780 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 3e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19781 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 3.53e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19782 FUN_028733 0 0 0 0 7 ptg000022l:3303672-3306437 Q96AY4 1.51e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19783 FUN_010518 2787 1095 1860 3042 1710 NA NA NA NA NA NA NA 19784 FUN_028739 40 5 0 3 44 ptg000022l:3339782-3347347 P21328 3.96e-26 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19785 FUN_042668 2471 759 853 1231 1358 NA NA NA NA NA NA NA 19786 FUN_042669 168 0 95 0 0 NA NA NA NA NA NA NA 19787 FUN_042662 206 259 407 579 555 ptg000039l:910857-911829 C3ZQF9 2.09e-27 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 19788 FUN_042663 239 163 202 293 197 NA NA NA NA NA NA NA 19789 FUN_042660 25 0 47 87 166 NA NA NA NA NA NA NA 19790 FUN_042661 0 11 117 20 123 NA NA NA NA NA NA NA 19791 FUN_042666 6739 7228 2853 6944 4858 NA NA NA NA NA NA NA 19792 FUN_042667 213213 99581 38599 124172 43220 NA NA NA NA NA NA NA 19793 FUN_042664 1363 1009 748 1378 1469 ptg000039l:929412-934920 Q96K37 3.62e-21 Solute carrier family 35 member E1 Homo sapiens (Human) NA GO:0005794; GO:0015297; GO:0016020 19794 FUN_042665 1410 898 360 731 663 NA NA NA NA NA NA NA 19795 FUN_041005 0 0 0 0 47 NA NA NA NA NA NA NA 19796 FUN_041004 31 35 17 7 144 NA NA NA NA NA NA NA 19797 FUN_041000 6 0 0 0 3 NA NA NA NA NA NA NA 19798 FUN_009344 57 1022 648 95 819 NA NA NA NA NA NA NA 19799 FUN_009345 3707 954 1336 3074 1249 NA NA NA NA NA NA NA 19800 FUN_009346 118 136 18 79 132 ptg000004l:5571350-5575771 P63016 1.02e-44 Paired box protein Pax-6 (Oculorhombin) Rattus norvegicus (Rat) anatomical structure development [GO:0048856]; anterior/posterior pattern specification [GO:0009952]; astrocyte differentiation [GO:0048708]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; blood vessel development [GO:0001568]; brain development [GO:0007420]; camera-type eye development [GO:0043010]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell fate determination [GO:0001709]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to prostaglandin E stimulus [GO:0071380]; cellular response to xenobiotic stimulus [GO:0071466]; central nervous system development [GO:0007417]; cerebellum development [GO:0021549]; cerebral cortex development [GO:0021987]; cerebral cortex regionalization [GO:0021796]; chromatin remodeling [GO:0006338]; commitment of neuronal cell to specific neuron type in forebrain [GO:0021902]; cornea development in camera-type eye [GO:0061303]; DNA demethylation [GO:0080111]; DNA methylation [GO:0006306]; dorsal/ventral axis specification [GO:0009950]; dorsal/ventral pattern formation [GO:0009953]; embryonic camera-type eye morphogenesis [GO:0048596]; epithelial cell development [GO:0002064]; establishment of mitotic spindle orientation [GO:0000132]; eye photoreceptor cell development [GO:0042462]; forebrain development [GO:0030900]; forebrain dorsal/ventral pattern formation [GO:0021798]; forebrain-midbrain boundary formation [GO:0021905]; gene expression [GO:0010467]; glandular epithelial cell differentiation [GO:0002067]; glucose homeostasis [GO:0042593]; habenula development [GO:0021986]; hindbrain development [GO:0030902]; histone acetylation [GO:0016573]; insulin metabolic process [GO:1901142]; interkinetic nuclear migration [GO:0022027]; iris morphogenesis [GO:0061072]; keratinocyte differentiation [GO:0030216]; lacrimal gland development [GO:0032808]; learned vocalization behavior or vocal learning [GO:0098598]; lens development in camera-type eye [GO:0002088]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural crest cell migration [GO:0001755]; neural precursor cell proliferation [GO:0061351]; neuroblast proliferation [GO:0007405]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; olfactory bulb development [GO:0021772]; olfactory bulb mitral cell layer development [GO:0061034]; oligodendrocyte cell fate specification [GO:0021778]; pallium development [GO:0021543]; pancreatic A cell development [GO:0003322]; pancreatic A cell differentiation [GO:0003310]; pituitary gland development [GO:0021983]; positive regulation of cell death [GO:0010942]; positive regulation of cell fate specification [GO:0042660]; positive regulation of core promoter binding [GO:1904798]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of gene expression [GO:0010628]; positive regulation of glucagon secretion [GO:0070094]; positive regulation of glutamatergic neuron differentiation [GO:0120008]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of neuron migration [GO:2001224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to organelle [GO:0033365]; protein phosphorylation [GO:0006468]; regionalization [GO:0003002]; regulation of asymmetric cell division [GO:0009786]; regulation of cell migration [GO:0030334]; regulation of gene expression [GO:0010468]; regulation of neurogenesis [GO:0050767]; regulation of neuron differentiation [GO:0045664]; regulation of neuron projection development [GO:0010975]; regulation of timing of cell differentiation [GO:0048505]; regulation of transcription by RNA polymerase II [GO:0006357]; response to ethanol [GO:0045471]; response to wounding [GO:0009611]; retina development in camera-type eye [GO:0060041]; rhombomere morphogenesis [GO:0021593]; salivary gland morphogenesis [GO:0007435]; sensory neuron migration [GO:1904937]; signal transduction involved in regulation of gene expression [GO:0023019]; smoothened signaling pathway [GO:0007224]; spinal cord development [GO:0021510]; telencephalon regionalization [GO:0021978]; transcription by RNA polymerase II [GO:0006366]; type B pancreatic cell differentiation [GO:0003309]; ventral spinal cord development [GO:0021517] GO:0000122; GO:0000132; GO:0000785; GO:0000976; GO:0000978; GO:0000979; GO:0000981; GO:0001221; GO:0001227; GO:0001228; GO:0001568; GO:0001709; GO:0001755; GO:0001764; GO:0001933; GO:0002052; GO:0002064; GO:0002067; GO:0002088; GO:0003002; GO:0003309; GO:0003310; GO:0003322; GO:0003677; GO:0003680; GO:0003682; GO:0003690; GO:0003700; GO:0003723; GO:0005634; GO:0005737; GO:0006306; GO:0006338; GO:0006357; GO:0006366; GO:0006468; GO:0007224; GO:0007405; GO:0007406; GO:0007409; GO:0007411; GO:0007417; GO:0007420; GO:0007435; GO:0008283; GO:0008285; GO:0009611; GO:0009786; GO:0009950; GO:0009952; GO:0009953; GO:0010467; GO:0010468; GO:0010628; GO:0010942; GO:0010975; GO:0016573; GO:0019901; GO:0021510; GO:0021517; GO:0021543; GO:0021549; GO:0021593; GO:0021772; GO:0021778; GO:0021796; GO:0021798; GO:0021902; GO:0021905; GO:0021978; GO:0021983; GO:0021986; GO:0021987; GO:0022027; GO:0023019; GO:0030154; GO:0030182; GO:0030216; GO:0030334; GO:0030858; GO:0030900; GO:0030902; GO:0031490; GO:0031625; GO:0032808; GO:0032869; GO:0033365; GO:0035035; GO:0042462; GO:0042593; GO:0042660; GO:0043010; GO:0043565; GO:0044344; GO:0045165; GO:0045471; GO:0045664; GO:0045665; GO:0045893; GO:0045944; GO:0048505; GO:0048596; GO:0048708; GO:0048856; GO:0050680; GO:0050767; GO:0060041; GO:0061034; GO:0061072; GO:0061303; GO:0061351; GO:0070094; GO:0070410; GO:0070412; GO:0071333; GO:0071380; GO:0071466; GO:0071837; GO:0080111; GO:0098598; GO:0120008; GO:1901142; GO:1904798; GO:1904937; GO:1990830; GO:1990837; GO:2000178; GO:2001224 19801 FUN_009347 1364 1253 834 1436 998 NA NA NA NA NA NA NA 19802 FUN_009341 24 0 29 38 237 NA NA NA NA NA NA NA 19803 FUN_009342 67 24 88 70 304 NA NA NA NA NA NA NA 19804 FUN_009343 94 758 244 609 579 NA NA NA NA NA NA NA 19805 FUN_009348 38 51 7 70 114 NA NA NA NA NA NA NA 19806 FUN_009349 1249 356 689 1222 904 NA NA NA NA NA NA NA 19807 FUN_022679 576 315 238 726 804 NA NA NA NA NA NA NA 19808 FUN_022678 55 8 23 21 10 ptg000016l:12358334-12359814 P61752 2.66e-21 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 19809 FUN_022673 1760 1819 1079 1441 1727 NA NA NA NA NA NA NA 19810 FUN_022672 418 155 160 335 345 NA NA NA NA NA NA NA 19811 FUN_022671 6124 5788 3734 5431 3083 NA NA NA NA NA NA NA 19812 FUN_022670 2203 1261 1515 2224 2023 NA NA NA NA NA NA NA 19813 FUN_022677 519 441 358 746 565 ptg000016l:12353161-12355684 B0G143 5.8e-47 Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B) Dictyostelium discoideum (Social amoeba) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0022857 19814 FUN_022676 5213 2931 3474 10332 10412 ptg000016l:12331637-12351387 P11087 2.37e-24 Collagen alpha-1(I) chain (Alpha-1 type I collagen) Mus musculus (Mouse) blood vessel development [GO:0001568]; bone trabecula formation [GO:0060346]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cellular response to amino acid stimulus [GO:0071230]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to fluoride [GO:1902618]; cellular response to mechanical stimulus [GO:0071260]; cellular response to retinoic acid [GO:0071300]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to vitamin E [GO:0071306]; collagen biosynthetic process [GO:0032964]; collagen fibril organization [GO:0030199]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; embryonic skeletal system development [GO:0048706]; endochondral ossification [GO:0001958]; extracellular matrix organization [GO:0030198]; face morphogenesis [GO:0060325]; intramembranous ossification [GO:0001957]; negative regulation of cell-substrate adhesion [GO:0010812]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cell migration [GO:0030335]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; protein localization to nucleus [GO:0034504]; protein transport [GO:0015031]; response to cAMP [GO:0051591]; response to corticosteroid [GO:0031960]; response to estradiol [GO:0032355]; response to hydrogen peroxide [GO:0042542]; response to hyperoxia [GO:0055093]; response to insulin [GO:0032868]; response to mechanical stimulus [GO:0009612]; response to xenobiotic stimulus [GO:0009410]; sensory perception of sound [GO:0007605]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; skin development [GO:0043588]; skin morphogenesis [GO:0043589]; tooth eruption [GO:0044691]; tooth mineralization [GO:0034505]; visual perception [GO:0007601]; wound healing [GO:0042060] GO:0001501; GO:0001503; GO:0001568; GO:0001649; GO:0001957; GO:0001958; GO:0002020; GO:0005201; GO:0005576; GO:0005581; GO:0005584; GO:0005615; GO:0005737; GO:0005783; GO:0005794; GO:0007601; GO:0007605; GO:0009410; GO:0009612; GO:0010718; GO:0010812; GO:0015031; GO:0030141; GO:0030198; GO:0030199; GO:0030335; GO:0031012; GO:0031960; GO:0032355; GO:0032868; GO:0032964; GO:0034504; GO:0034505; GO:0038063; GO:0042060; GO:0042542; GO:0042802; GO:0043588; GO:0043589; GO:0044344; GO:0044691; GO:0045893; GO:0046872; GO:0048407; GO:0048705; GO:0048706; GO:0051591; GO:0055093; GO:0060325; GO:0060346; GO:0060351; GO:0062023; GO:0071230; GO:0071260; GO:0071300; GO:0071306; GO:0071356; GO:0071364; GO:0071560; GO:0090263; GO:1902618 19815 FUN_022675 3426 3610 1934 2674 3360 ptg000016l:12322312-12331081 Q29RQ3 1.65e-27 Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1) Bos taurus (Bovine) microtubule-based movement [GO:0007018]; transport along microtubule [GO:0010970] GO:0000776; GO:0000922; GO:0005737; GO:0005868; GO:0005874; GO:0007018; GO:0010970; GO:0031982; GO:0045503; GO:0045504 19816 FUN_022675 3426 3610 1934 2674 3360 ptg000016l:12322312-12331081 Q29RQ3 1.65e-27 Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1) Bos taurus (Bovine) microtubule-based movement [GO:0007018]; transport along microtubule [GO:0010970] GO:0000776; GO:0000922; GO:0005737; GO:0005868; GO:0005874; GO:0007018; GO:0010970; GO:0031982; GO:0045503; GO:0045504 19817 FUN_022674 43 73 26 0 0 NA NA NA NA NA NA NA 19818 FUN_032269 42 182 16 56 71 NA NA NA NA NA NA NA 19819 FUN_032268 58 65 220 213 129 ptg000023l:30351124-30357639 Q9MYM7 8.92e-25 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 19820 FUN_032268 58 65 220 213 129 ptg000023l:30351124-30357639 Q9MYM7 6.43e-24 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 19821 FUN_010075 0 0 2 0 12 NA NA NA NA NA NA NA 19822 FUN_010070 0 0 0 0 14 NA NA NA NA NA NA NA 19823 FUN_006291 223 5 10 8 84 NA NA NA NA NA NA NA 19824 FUN_006297 0 0 11 0 0 NA NA NA NA NA NA NA 19825 FUN_009839 909 1393 657 1241 397 ptg000004l:12420446-12427764 P58354 1.17e-48 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Bos taurus (Bovine) dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; glucose transmembrane transport [GO:1904659] GO:0005353; GO:0005355; GO:0005886; GO:0015755; GO:0030659; GO:0033300; GO:0070837; GO:1904659 19826 FUN_009832 11 0 33 136 97 NA NA NA NA NA NA NA 19827 FUN_009833 37 11 625 2930 1768 NA NA NA NA NA NA NA 19828 FUN_009830 2611 1503 1275 2520 2279 NA NA NA NA NA NA NA 19829 FUN_009831 8 8 0 0 7 NA NA NA NA NA NA NA 19830 FUN_009836 5989 3071 1931 6330 5042 NA NA NA NA NA NA NA 19831 FUN_009837 1100 840 992 1907 385 ptg000004l:12397267-12405491 A9ZSY2 4.69e-42 Facilitated trehalose transporter Tret1 (AmTRET1) Apis mellifera ligustica (Common honeybee) (Italian honeybee) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 19832 FUN_009834 50 11 24 23 16 NA NA NA NA NA NA NA 19833 FUN_009835 204 169 138 267 262 NA NA NA NA NA NA NA 19834 FUN_043347 2234 1061 783 1208 1261 NA NA NA NA NA NA NA 19835 FUN_024509 87 26 42 26 13 NA NA NA NA NA NA NA 19836 FUN_008129 331 69 192 211 71 ptg000002l:8414798-8422210 Q9QZE7 1.97e-59 Translin-associated protein X (Translin-associated factor X) Mus musculus (Mouse) cell differentiation [GO:0030154]; siRNA processing [GO:0030422]; spermatogenesis [GO:0007283] GO:0003697; GO:0003723; GO:0004521; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0007283; GO:0030154; GO:0030422; GO:0031687; GO:0043565; GO:0044877; GO:0046872; GO:0048471; GO:1902555 19837 FUN_024536 0 120 141 313 186 ptg000018l:8026629-8030511 Q96AY4 2.78e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19838 FUN_024536 0 120 141 313 186 ptg000018l:8026629-8030511 Q96AY4 1.07e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19839 FUN_024536 0 120 141 313 186 ptg000018l:8026629-8030511 Q96AY4 1.97e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19840 FUN_024536 0 120 141 313 186 ptg000018l:8026629-8030511 Q96AY4 1.01e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19841 FUN_008126 0 0 18 0 18 NA NA NA NA NA NA NA 19842 FUN_024535 0 4 2 0 10 NA NA NA NA NA NA NA 19843 FUN_008123 348 281 349 280 240 NA NA NA NA NA NA NA 19844 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 8.92e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19845 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 1.5e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19846 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 2.43e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19847 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 3.19e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19848 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 8.27e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19849 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 5.24e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19850 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 4.44e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19851 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 1.39e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19852 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 1.37e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19853 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 2.13e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19854 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 2.85e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19855 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 3.01e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19856 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 3.22e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19857 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 1.09e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19858 FUN_024530 0 20 2 16 23 ptg000018l:7981089-7982427 Q80XJ3 2.62e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 19859 FUN_015169 55 39 6 6 6 NA NA NA NA NA NA NA 19860 FUN_015168 27 16 11 32 10 NA NA NA NA NA NA NA 19861 FUN_015165 730 644 304 816 686 NA NA NA NA NA NA NA 19862 FUN_015164 4487 1967 1582 3454 4110 ptg000009l:6931113-6984237 Q94K49 7.49e-25 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 19863 FUN_015167 3901 2222 1570 3205 2038 NA NA NA NA NA NA NA 19864 FUN_015166 236 110 156 163 207 NA NA NA NA NA NA NA 19865 FUN_015161 34 0 0 0 46 NA NA NA NA NA NA NA 19866 FUN_015160 61 43 14 0 100 NA NA NA NA NA NA NA 19867 FUN_015163 22 0 0 20 51 NA NA NA NA NA NA NA 19868 FUN_024280 21 20 4 7 5 ptg000018l:4313028-4330482 Q8K3Z0 9.5e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 19869 FUN_024281 21 175 30 100 17 ptg000018l:4342274-4347272 Q8K3Z0 7.51e-36 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 19870 FUN_024282 0 0 62 18 0 NA NA NA NA NA NA NA 19871 FUN_024283 9 12 82 129 18 NA NA NA NA NA NA NA 19872 FUN_024284 52 107 41 246 69 ptg000018l:4372771-4376353 Q7RTR2 1.37e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19873 FUN_024286 30 27 11 9 6 ptg000018l:4399281-4402182 Q8K3Z0 1.94e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 19874 FUN_024287 0 0 0 0 20 NA NA NA NA NA NA NA 19875 FUN_024288 94 0 0 3 173 ptg000018l:4410080-4420663 Q7RTR2 3.88e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 19876 FUN_024289 35 0 18 0 198 NA NA NA NA NA NA NA 19877 FUN_038561 457 115 226 453 0 NA NA NA NA NA NA NA 19878 FUN_038562 265 99 151 234 226 ptg000027l:8755578-8759295 Q64WY5 4e-48 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Bacteroides fragilis (strain YCH46) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 19879 FUN_038562 265 99 151 234 226 ptg000027l:8755578-8759295 Q64WY5 1.55e-35 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Bacteroides fragilis (strain YCH46) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 19880 FUN_038563 58060 99436 202096 23110 537 NA NA NA NA NA NA NA 19881 FUN_038564 57559 104254 183930 29327 616 NA NA NA NA NA NA NA 19882 FUN_038565 3587 2405 2535 5497 3371 ptg000027l:8787902-8794296 A6QLE6 1.42e-91 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 19883 FUN_038566 637 174 174 402 388 ptg000027l:8806060-8809562 A6QLE6 2.22e-108 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 19884 FUN_038567 225 79 74 169 222 NA NA NA NA NA NA NA 19885 FUN_038568 6484 3038 2902 6815 3657 ptg000027l:8821143-8827202 A2AHL1 8.12e-90 Anoctamin-3 (Transmembrane protein 16C) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; chloride transmembrane transport [GO:1902476]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005886; GO:0016048; GO:0017128; GO:0046983; GO:0050982; GO:0051649; GO:0055085; GO:0061590; GO:0061591; GO:1902476 19886 FUN_038568 6484 3038 2902 6815 3657 ptg000027l:8821143-8827202 A2AHL1 1.43e-21 Anoctamin-3 (Transmembrane protein 16C) Mus musculus (Mouse) calcium activated galactosylceramide scrambling [GO:0061591]; calcium activated phosphatidylcholine scrambling [GO:0061590]; chloride transmembrane transport [GO:1902476]; detection of mechanical stimulus [GO:0050982]; detection of temperature stimulus [GO:0016048]; establishment of localization in cell [GO:0051649]; transmembrane transport [GO:0055085] GO:0005254; GO:0005886; GO:0016048; GO:0017128; GO:0046983; GO:0050982; GO:0051649; GO:0055085; GO:0061590; GO:0061591; GO:1902476 19887 FUN_038569 6458 4104 2810 5931 4310 ptg000027l:8829765-8837651 A6QLE6 2e-63 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 19888 FUN_038569 6458 4104 2810 5931 4310 ptg000027l:8829765-8837651 A6QLE6 4.53e-26 Anoctamin-4 (Transmembrane protein 16D) Bos taurus (Bovine) chloride transmembrane transport [GO:1902476]; lipid transport [GO:0006869]; transmembrane transport [GO:0055085] GO:0005229; GO:0005254; GO:0005886; GO:0006869; GO:0046983; GO:0055085; GO:1902476 19889 FUN_025264 1186 953 611 761 627 ptg000019l:569975-582782 Q9ET47 1.62e-25 Espin (Ectoplasmic specialization protein) Mus musculus (Mouse) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; locomotory behavior [GO:0007626]; microvillar actin bundle assembly [GO:0030034]; negative regulation of cytoskeleton organization [GO:0051494]; parallel actin filament bundle assembly [GO:0030046]; positive regulation of filopodium assembly [GO:0051491]; sensory perception of sound [GO:0007605] GO:0005737; GO:0005829; GO:0005902; GO:0005903; GO:0007605; GO:0007626; GO:0015629; GO:0017124; GO:0030034; GO:0030046; GO:0031941; GO:0032420; GO:0032421; GO:0032426; GO:0043197; GO:0051015; GO:0051017; GO:0051491; GO:0051494; GO:0051639; GO:0070161 19890 FUN_013868 80 0 0 0 53 NA NA NA NA NA NA NA 19891 FUN_013869 6 19 0 9 30 NA NA NA NA NA NA NA 19892 FUN_041581 10084 12362 7173 10431 8835 NA NA NA NA NA NA NA 19893 FUN_041586 2778 2001 1169 2571 1218 ptg000035l:5519771-5525928 Q4VSN1 6.37e-28 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; notochord cell vacuolation [GO:0060036]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0060036; GO:0070161; GO:0070374; GO:0106310 19894 FUN_013867 0 0 15 99 4 NA NA NA NA NA NA NA 19895 FUN_022694 939 615 653 1013 915 NA NA NA NA NA NA NA 19896 FUN_039211 0 39 0 0 13 NA NA NA NA NA NA NA 19897 FUN_039210 0 0 2 205 0 NA NA NA NA NA NA NA 19898 FUN_039213 0 0 17 0 12 NA NA NA NA NA NA NA 19899 FUN_039215 14 0 0 0 28 NA NA NA NA NA NA NA 19900 FUN_039217 0 1 10 0 22 NA NA NA NA NA NA NA 19901 FUN_039219 0 0 0 0 7 ptg000027l:15662569-15663456 P35061 1.76e-82 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19902 FUN_039218 11 0 14 7 76 NA NA NA NA NA NA NA 19903 FUN_035693 5301 3754 2416 4472 2722 NA NA NA NA NA NA NA 19904 FUN_021929 374 365 429 717 922 NA NA NA NA NA NA NA 19905 FUN_027167 0 0 0 7 0 NA NA NA NA NA NA NA 19906 FUN_027168 2 0 196 8 512 NA NA NA NA NA NA NA 19907 FUN_027169 0 41 8 0 12 NA NA NA NA NA NA NA 19908 FUN_035699 2 0 18 0 26 NA NA NA NA NA NA NA 19909 FUN_035698 15 0 20 9 118 NA NA NA NA NA NA NA 19910 FUN_032266 5 33 33 15 100 ptg000023l:30330635-30334861 Q9MYM7 4.8e-27 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 19911 FUN_028468 771 101 277 126 572 NA NA NA NA NA NA NA 19912 FUN_041068 0 0 0 10 0 NA NA NA NA NA NA NA 19913 FUN_041060 0 9 0 0 0 NA NA NA NA NA NA NA 19914 FUN_001964 30 0 36 11 0 NA NA NA NA NA NA NA 19915 FUN_041063 0 0 23 0 0 NA NA NA NA NA NA NA 19916 FUN_041065 74 7 0 6 95 NA NA NA NA NA NA NA 19917 FUN_041064 0 34 0 0 11 NA NA NA NA NA NA NA 19918 FUN_041067 0 0 0 6 0 NA NA NA NA NA NA NA 19919 FUN_014812 1780 2631 2195 3586 3232 NA NA NA NA NA NA NA 19920 FUN_023263 702 636 458 350 58 NA NA NA NA NA NA NA 19921 FUN_023262 1244 550 680 861 1189 NA NA NA NA NA NA NA 19922 FUN_023261 2548 1923 1228 1738 1000 NA NA NA NA NA NA NA 19923 FUN_023260 3791 2271 1393 3044 2100 ptg000017l:5641637-5655228 Q9W676 7.59e-23 LIM domain-binding protein 2 (LDB-2) (Carboxyl-terminal LIM domain-binding protein 1) (CLIM-1) (LIM domain-binding factor CLIM1) (cLdb2) Gallus gallus (Chicken) negative regulation of transcription by RNA polymerase II [GO:0000122]; nervous system development [GO:0007399]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005634; GO:0005667; GO:0007399; GO:0030274; GO:0045944 19924 FUN_023266 503 265 70 63 67 ptg000017l:5723720-5725001 Q7LGC8 3.16e-32 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0) (GST-0) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790]; T cell homeostasis [GO:0043029] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206; GO:0043029; GO:0050698 19925 FUN_023265 233 25 84 25 34 ptg000017l:5701287-5704744 P21328 3.41e-29 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19926 FUN_023269 2106 999 1018 1888 1389 NA NA NA NA NA NA NA 19927 FUN_023268 1069 380 514 683 428 ptg000017l:5739957-5796496 P21328 6.8e-35 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 19928 FUN_014019 1 0 0 0 22 NA NA NA NA NA NA NA 19929 FUN_014011 0 0 0 0 22 NA NA NA NA NA NA NA 19930 FUN_014016 0 0 0 0 9 NA NA NA NA NA NA NA 19931 FUN_014017 0 0 0 0 28 NA NA NA NA NA NA NA 19932 FUN_014015 0 0 186 67 87 NA NA NA NA NA NA NA 19933 FUN_000034 1 0 7 13 22 NA NA NA NA NA NA NA 19934 FUN_030464 7 1 8 0 35 ptg000023l:10931054-10931817 P84239 5.16e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19935 FUN_033910 421 342 207 306 367 NA NA NA NA NA NA NA 19936 FUN_033911 5459 4183 2067 4470 2945 NA NA NA NA NA NA NA 19937 FUN_033912 1743 1047 654 1570 1105 NA NA NA NA NA NA NA 19938 FUN_033913 1399 886 539 1035 615 NA NA NA NA NA NA NA 19939 FUN_033914 0 0 16 4 5 NA NA NA NA NA NA NA 19940 FUN_033915 2124 1487 1108 1394 1158 NA NA NA NA NA NA NA 19941 FUN_033916 2631 3130 1828 2437 992 NA NA NA NA NA NA NA 19942 FUN_033917 987 844 1020 1356 609 NA NA NA NA NA NA NA 19943 FUN_033919 165 188 149 108 212 NA NA NA NA NA NA NA 19944 FUN_018817 81 0 10 8 0 NA NA NA NA NA NA NA 19945 FUN_018815 0 0 0 10 0 NA NA NA NA NA NA NA 19946 FUN_018812 0 0 0 0 11 NA NA NA NA NA NA NA 19947 FUN_018813 18 0 33 0 7 NA NA NA NA NA NA NA 19948 FUN_018810 34 72 0 0 10 NA NA NA NA NA NA NA 19949 FUN_018811 0 11 0 0 0 NA NA NA NA NA NA NA 19950 FUN_030154 12 0 27 29 90 NA NA NA NA NA NA NA 19951 FUN_030298 3 0 6 1 24 ptg000023l:10557173-10557936 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19952 FUN_030299 25 3 28 5 213 ptg000023l:10558200-10559187 Q6LAF1 6.31e-44 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19953 FUN_030296 4 0 6 0 19 ptg000023l:10553122-10553885 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19954 FUN_030294 5 0 7 0 22 ptg000023l:10549070-10549833 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19955 FUN_030292 6 0 6 0 20 ptg000023l:10545019-10545782 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19956 FUN_030290 5 0 5 1 23 ptg000023l:10540967-10541730 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19957 FUN_021135 51 41 0 43 23 NA NA NA NA NA NA NA 19958 FUN_021137 0 0 15 0 92 NA NA NA NA NA NA NA 19959 FUN_014803 1606 697 408 1873 1401 ptg000009l:3229588-3243604 Q3UQ28 0 Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] Mus musculus (Mouse) angiogenesis [GO:0001525]; basement membrane assembly [GO:0070831]; basement membrane organization [GO:0071711]; cell adhesion [GO:0007155]; collagen fibril organization [GO:0030199]; extracellular matrix organization [GO:0030198]; eye development [GO:0001654]; hydrogen peroxide catabolic process [GO:0042744]; protein homooligomerization [GO:0051260]; protein homotrimerization [GO:0070207]; response to oxidative stress [GO:0006979] GO:0001525; GO:0001654; GO:0004601; GO:0005201; GO:0005604; GO:0005615; GO:0005783; GO:0006979; GO:0007155; GO:0009986; GO:0016684; GO:0020037; GO:0030198; GO:0030199; GO:0031012; GO:0042744; GO:0043237; GO:0046872; GO:0051260; GO:0062023; GO:0070207; GO:0070831; GO:0071711; GO:0140825 19960 FUN_013857 0 0 0 0 18 NA NA NA NA NA NA NA 19961 FUN_019831 5 0 0 6 15 NA NA NA NA NA NA NA 19962 FUN_005334 1924 3116 1436 2206 1286 NA NA NA NA NA NA NA 19963 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 2.49e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19964 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 5.73e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19965 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 1.77e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19966 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 3.94e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19967 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 8.99e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19968 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 9.5e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19969 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 2.38e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19970 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 3.46e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19971 FUN_009860 21 19 14 13 9 ptg000004l:12665850-12668625 Q96AY4 4.27e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 19972 FUN_014505 25456 21219 13835 22006 19141 ptg000009l:746570-749470 Q8BH44 1.29e-44 Coronin-2B Mus musculus (Mouse) focal adhesion assembly [GO:0048041]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of establishment of protein localization [GO:1904950]; negative regulation of stress fiber assembly [GO:0051497]; positive regulation of establishment of protein localization [GO:1904951]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cellular response to stress [GO:0080135]; regulation of glomerular filtration [GO:0003093] GO:0001725; GO:0003093; GO:0005737; GO:0005925; GO:0010812; GO:0017166; GO:0032956; GO:0048041; GO:0051015; GO:0051497; GO:0080135; GO:1904950; GO:1904951; GO:1990147 19973 FUN_022240 2722 1427 321 858 1205 NA NA NA NA NA NA NA 19974 FUN_014507 29 27 5 47 27 NA NA NA NA NA NA NA 19975 FUN_014500 2626 2691 2401 2158 1834 ptg000009l:681469-684543 Q641W2 6.3e-38 MYG1 exonuclease (EC 3.1.-.-) Rattus norvegicus (Rat) locomotory exploration behavior [GO:0035641] GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0035641 19976 FUN_014500 2626 2691 2401 2158 1834 ptg000009l:681469-684543 Q641W2 6.3e-38 MYG1 exonuclease (EC 3.1.-.-) Rattus norvegicus (Rat) locomotory exploration behavior [GO:0035641] GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0035641 19977 FUN_014500 2626 2691 2401 2158 1834 ptg000009l:681469-684543 Q641W2 6.3e-38 MYG1 exonuclease (EC 3.1.-.-) Rattus norvegicus (Rat) locomotory exploration behavior [GO:0035641] GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0035641 19978 FUN_014500 2626 2691 2401 2158 1834 ptg000009l:681469-684543 Q641W2 3.25e-21 MYG1 exonuclease (EC 3.1.-.-) Rattus norvegicus (Rat) locomotory exploration behavior [GO:0035641] GO:0004518; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005759; GO:0035641 19979 FUN_035408 1407 923 965 1754 855 ptg000025l:7133554-7141000 Q9Y3D0 4.62e-26 Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) Homo sapiens (Human) chromosome segregation [GO:0007059]; iron-sulfur cluster assembly [GO:0016226]; protein maturation by [4Fe-4S] cluster transfer [GO:0106035]; protein maturation by iron-sulfur cluster transfer [GO:0097428] GO:0005634; GO:0005654; GO:0005737; GO:0005819; GO:0005829; GO:0007059; GO:0016226; GO:0030496; GO:0071817; GO:0097361; GO:0097428; GO:0106035 19980 FUN_035409 970 946 401 489 371 ptg000025l:7142562-7145354 A2RT91 5.98e-84 Ankyrin and armadillo repeat-containing protein Mus musculus (Mouse) NA GO:0016020 19981 FUN_030439 9 0 9 1 40 ptg000023l:10870272-10871035 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19982 FUN_035401 2373 1846 1621 2524 1796 NA NA NA NA NA NA NA 19983 FUN_035403 1212 676 415 948 816 NA NA NA NA NA NA NA 19984 FUN_035405 322 106 62 281 128 NA NA NA NA NA NA NA 19985 FUN_035406 2690 2134 1292 2319 1886 NA NA NA NA NA NA NA 19986 FUN_030435 9 0 9 1 32 ptg000023l:10862168-10862931 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 19987 FUN_038609 0 5 0 4 206 NA NA NA NA NA NA NA 19988 FUN_038608 633 557 601 583 312 NA NA NA NA NA NA NA 19989 FUN_004929 1432 1297 656 1359 1269 NA NA NA NA NA NA NA 19990 FUN_004928 55 31 20 22 36 NA NA NA NA NA NA NA 19991 FUN_004923 3206 3069 2608 5300 3857 NA NA NA NA NA NA NA 19992 FUN_038600 10 5 0 11 20 NA NA NA NA NA NA NA 19993 FUN_038603 14 7 0 10 10 NA NA NA NA NA NA NA 19994 FUN_038602 7 11 0 0 43 NA NA NA NA NA NA NA 19995 FUN_038605 0 11 0 0 0 NA NA NA NA NA NA NA 19996 FUN_004926 1036 1033 475 1021 878 NA NA NA NA NA NA NA 19997 FUN_038607 3584 2198 3077 3174 3561 NA NA NA NA NA NA NA 19998 FUN_004924 731 513 371 387 575 NA NA NA NA NA NA NA 19999 FUN_031529 109 22 74 140 47 ptg000023l:22528802-22534960 Q40723 5.64e-26 Ras-related protein RGP2 (GTP-binding regulatory protein RGP2) Oryza sativa subsp. japonica (Rice) NA GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005886 20000 FUN_031528 32 0 10 40 57 NA NA NA NA NA NA NA 20001 FUN_031527 123 73 57 171 98 ptg000023l:22509446-22524214 Q7T3A4 9.56e-27 Ras-related protein Rab-13 Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; bicellular tight junction assembly [GO:0070830]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; endothelial cell chemotaxis [GO:0035767]; Golgi vesicle fusion to target membrane [GO:0048210]; neuron projection development [GO:0031175]; protein kinase A signaling [GO:0010737]; protein localization to cell leading edge [GO:1902463]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; trans-Golgi network to recycling endosome transport [GO:0044795]; vesicle docking involved in exocytosis [GO:0006904] GO:0001525; GO:0003924; GO:0005525; GO:0005768; GO:0005802; GO:0005886; GO:0005923; GO:0006904; GO:0008021; GO:0009306; GO:0010737; GO:0016328; GO:0017157; GO:0030027; GO:0030139; GO:0030140; GO:0030866; GO:0031175; GO:0031410; GO:0032456; GO:0032593; GO:0032869; GO:0035767; GO:0043005; GO:0043231; GO:0044795; GO:0048210; GO:0055037; GO:0055038; GO:0070830; GO:0072659; GO:1902463 20002 FUN_031526 257 108 70 60 162 ptg000023l:22502494-22505112 P00532 4.07e-30 Serine/threonine-protein kinase-transforming protein raf (EC 2.7.11.1) Murine sarcoma virus 3611 protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 20003 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 0 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20004 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 5.98e-101 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20005 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.48e-85 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20006 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 3.85e-83 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20007 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 6.49e-78 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20008 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 7.89e-76 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20009 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 9.89e-76 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20010 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.72e-75 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20011 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.37e-70 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20012 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 3.45e-64 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20013 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.31e-55 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20014 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 8.77e-48 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20015 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 5.16e-44 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20016 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 1.83e-36 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20017 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 6.32e-32 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20018 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 3.04e-31 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20019 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.92e-28 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20020 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 5.69e-28 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20021 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.45e-26 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20022 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 1.41e-25 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20023 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 4.46e-25 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20024 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 8.18e-24 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20025 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.28e-22 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20026 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 2.3e-22 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20027 FUN_031525 3957 2310 2754 5311 4506 ptg000023l:22456149-22500277 O75445 9.81e-21 Usherin (Usher syndrome type IIa protein) (Usher syndrome type-2A protein) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20028 FUN_031524 619 545 287 280 323 ptg000023l:22451556-22455542 Q53GS7 5.54e-60 mRNA export factor GLE1 (hGLE1) (GLE1 RNA export mediator) (GLE1-like protein) (Nucleoporin GLE1) Homo sapiens (Human) mRNA export from nucleus [GO:0006406]; nucleocytoplasmic transport [GO:0006913]; poly(A)+ mRNA export from nucleus [GO:0016973]; protein transport [GO:0015031] GO:0000822; GO:0005543; GO:0005615; GO:0005635; GO:0005643; GO:0005730; GO:0005737; GO:0005813; GO:0005814; GO:0005829; GO:0006406; GO:0006913; GO:0015031; GO:0016020; GO:0016973; GO:0031369; GO:0031965; GO:0036064; GO:0042802; GO:0044614 20029 FUN_031523 369 155 339 376 530 ptg000023l:22445126-22448802 Q5RF14 1.66e-106 Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0046872 20030 FUN_031523 369 155 339 376 530 ptg000023l:22445126-22448802 Q5RF14 1.69e-57 Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0046872 20031 FUN_031523 369 155 339 376 530 ptg000023l:22445126-22448802 Q5RF14 3.89e-26 Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) proteolysis [GO:0006508] GO:0004222; GO:0005759; GO:0006508; GO:0046872 20032 FUN_031522 3920 3284 2342 3508 2044 NA NA NA NA NA NA NA 20033 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 1.32e-71 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20034 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 1.32e-71 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20035 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 1.21e-34 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20036 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 1.41e-28 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20037 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 2.05e-27 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20038 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 6.38e-27 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20039 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 8.56e-25 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20040 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 6.92e-24 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20041 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 1.17e-23 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20042 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 5.32e-23 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20043 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 5e-22 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20044 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 4.32e-21 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20045 FUN_031521 2852 450 557 2320 580 ptg000023l:22373896-22437008 Q8K3K1 9.09e-21 Usherin (Usher syndrome type IIa protein homolog) (Usher syndrome type-2A protein homolog) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; cell migration [GO:0016477]; establishment of localization in cell [GO:0051649]; establishment of protein localization [GO:0045184]; hair cell differentiation [GO:0035315]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear receptor cell differentiation [GO:0060113]; maintenance of animal organ identity [GO:0048496]; photoreceptor cell maintenance [GO:0045494]; response to stimulus [GO:0050896]; retina development in camera-type eye [GO:0060041]; sensory perception of light stimulus [GO:0050953]; sensory perception of sound [GO:0007605]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; visual perception [GO:0007601] GO:0001917; GO:0002141; GO:0002142; GO:0005518; GO:0005576; GO:0005604; GO:0005737; GO:0007601; GO:0007605; GO:0009887; GO:0009888; GO:0016324; GO:0016477; GO:0017022; GO:0032391; GO:0032420; GO:0032421; GO:0034446; GO:0035315; GO:0036064; GO:0042491; GO:0042802; GO:0045184; GO:0045202; GO:0045494; GO:0048496; GO:0050896; GO:0050953; GO:0051649; GO:0060041; GO:0060113; GO:0060171; GO:1990075; GO:1990696 20046 FUN_031520 23 12 5 22 3 NA NA NA NA NA NA NA 20047 FUN_028994 2196 1180 1106 1905 1550 NA NA NA NA NA NA NA 20048 FUN_020778 0 0 0 0 16 NA NA NA NA NA NA NA 20049 FUN_020779 1 8 12 4 4 NA NA NA NA NA NA NA 20050 FUN_020770 10 0 0 0 0 NA NA NA NA NA NA NA 20051 FUN_020771 0 0 0 145 52 NA NA NA NA NA NA NA 20052 FUN_020772 0 0 0 35 0 NA NA NA NA NA NA NA 20053 FUN_020774 0 35 0 345 0 NA NA NA NA NA NA NA 20054 FUN_014736 160 202 142 127 221 NA NA NA NA NA NA NA 20055 FUN_024599 193 0 24 21 0 NA NA NA NA NA NA NA 20056 FUN_036179 923 617 868 756 812 NA NA NA NA NA NA NA 20057 FUN_036178 291 251 459 589 374 NA NA NA NA NA NA NA 20058 FUN_036171 1634 329 354 1290 401 ptg000025l:16001415-16043477 Q7Z442 6.39e-37 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 20059 FUN_036170 0 0 0 12 0 NA NA NA NA NA NA NA 20060 FUN_036173 616 211 151 731 129 NA NA NA NA NA NA NA 20061 FUN_036172 633 409 210 508 398 ptg000025l:16045408-16048062 O88483 6.61e-28 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (PDP 1) (EC 3.1.3.43) (Protein phosphatase 2C) (Pyruvate dehydrogenase phosphatase catalytic subunit 1) (PDPC 1) Rattus norvegicus (Rat) peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of pyruvate dehydrogenase activity [GO:1904184]; protein dephosphorylation [GO:0006470] GO:0000287; GO:0004722; GO:0004741; GO:0005509; GO:0005739; GO:0005759; GO:0006470; GO:0019909; GO:0035970; GO:0044877; GO:1904184 20062 FUN_036175 4084 3431 3089 2620 2270 NA NA NA NA NA NA NA 20063 FUN_036174 50 39 45 45 21 NA NA NA NA NA NA NA 20064 FUN_036177 2337 1754 1401 2876 1625 NA NA NA NA NA NA NA 20065 FUN_036176 11457 11547 7669 10107 8262 ptg000025l:16075084-16078187 Q3T112 3.33e-26 Proteasome subunit beta type-8 (EC 3.4.25.1) (Proteasome subunit beta-5i) Bos taurus (Bovine) antigen processing and presentation [GO:0019882]; fat cell differentiation [GO:0045444]; proteasomal protein catabolic process [GO:0010498]; regulation of endopeptidase activity [GO:0052548] GO:0004175; GO:0004298; GO:0005634; GO:0005737; GO:0005839; GO:0010498; GO:0019774; GO:0019882; GO:0045444; GO:0052548; GO:1990111 20066 FUN_030156 0 0 0 0 13 NA NA NA NA NA NA NA 20067 FUN_037802 3374 1959 873 1666 1564 NA NA NA NA NA NA NA 20068 FUN_037803 0 10 6 12 5 NA NA NA NA NA NA NA 20069 FUN_037800 109 93 95 144 235 NA NA NA NA NA NA NA 20070 FUN_037801 46 67 83 81 71 ptg000026l:13713781-13721072 Q8INF0 1.16e-54 Soluble guanylate cyclase 88E (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0003924; GO:0004383; GO:0005525; GO:0008074; GO:0019825; GO:0019826; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0042803; GO:0046872; GO:0046982; GO:0070025; GO:0070026; GO:0070482 20071 FUN_037806 9051 4648 995 6198 3087 NA NA NA NA NA NA NA 20072 FUN_037807 461 341 275 535 393 ptg000026l:13770359-13778417 Q8INF0 2.02e-55 Soluble guanylate cyclase 88E (EC 4.6.1.2) Drosophila melanogaster (Fruit fly) cGMP-mediated signaling [GO:0019934]; nitric oxide-cGMP-mediated signaling pathway [GO:0038060]; response to hypoxia [GO:0001666]; response to oxygen levels [GO:0070482]; response to reactive oxygen species [GO:0000302] GO:0000302; GO:0001666; GO:0003924; GO:0004383; GO:0005525; GO:0008074; GO:0019825; GO:0019826; GO:0019899; GO:0019934; GO:0020037; GO:0038060; GO:0042803; GO:0046872; GO:0046982; GO:0070025; GO:0070026; GO:0070482 20073 FUN_037804 72 295 81 105 103 ptg000026l:13747949-13748672 Q20201 5.44e-32 Transcription factor sox-3 Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0030154; GO:0030182; GO:0043565 20074 FUN_024591 0 17 11 9 4 NA NA NA NA NA NA NA 20075 FUN_037808 2923 2770 967 2099 2478 NA NA NA NA NA NA NA 20076 FUN_037809 2134 2185 847 1413 911 ptg000026l:13806966-13818800 Q66J69 7.8e-21 E3 ubiquitin-protein ligase RING2-A (EC 2.3.2.27) (RING finger protein 1B-A) (RING1b-A) (RING finger protein 2-A) (RING-type E3 ubiquitin transferase RING2-A) Xenopus laevis (African clawed frog) histone H2A monoubiquitination [GO:0035518]; histone H2A-K119 monoubiquitination [GO:0036353]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0005634; GO:0005694; GO:0005737; GO:0031519; GO:0035102; GO:0035518; GO:0036353; GO:0046872; GO:0061630; GO:0071339 20077 FUN_024592 1724 1332 704 1898 2126 ptg000018l:8772065-8781509 Q9SUR9 1.66e-28 Protein SGT1 homolog A (AtSGT1a) (Suppressor of G2 allele of SKP1 homolog A) Arabidopsis thaliana (Mouse-ear cress) cellular response to auxin stimulus [GO:0071365]; cellular response to hypoxia [GO:0071456]; defense response [GO:0006952]; defense response to fungus [GO:0050832]; embryo development ending in seed dormancy [GO:0009793]; innate immune response [GO:0045087]; protein stabilization [GO:0050821]; regulation of defense response to fungus [GO:1900150]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005737; GO:0005829; GO:0006511; GO:0006952; GO:0009793; GO:0019005; GO:0045087; GO:0050821; GO:0050832; GO:0051087; GO:0071365; GO:0071456; GO:1900150 20078 FUN_005322 269 341 228 405 288 ntLink_8:34018697-34026185 Q9NQX0 9.47e-45 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 20079 FUN_005322 269 341 228 405 288 ntLink_8:34018697-34026185 Q9NQX0 6.89e-21 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 20080 FUN_000131 1 0 4 0 11 ntLink_4:194041-194822 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20081 FUN_000133 32 4 31 4 133 ntLink_4:197895-198207 Q6LAF1 1.14e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20082 FUN_005326 14 37 34 54 21 NA NA NA NA NA NA NA 20083 FUN_005327 1007 171 344 858 1207 ntLink_8:34059505-34064184 Q3UZD5 3.15e-39 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 20084 FUN_005327 1007 171 344 858 1207 ntLink_8:34059505-34064184 Q3UZD5 4.65e-21 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 20085 FUN_005324 252 121 129 84 100 ntLink_8:34047081-34050314 A6QPM3 7.33e-43 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Bos taurus (Bovine) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; regulation of gene expression [GO:0010468] GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0046872; GO:0140944 20086 FUN_005325 4 0 0 0 18 NA NA NA NA NA NA NA 20087 FUN_000138 2 0 6 0 12 ntLink_4:206223-207002 P84239 4.85e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20088 FUN_024594 425 161 208 380 312 ptg000018l:8786541-8792013 Q8R0F3 2.26e-24 Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (C-alpha-formylglycine-generating enzyme 1) (Sulfatase-modifying factor 1) Mus musculus (Mouse) post-translational protein modification [GO:0043687]; protein oxidation [GO:0018158] GO:0005783; GO:0005788; GO:0018158; GO:0042802; GO:0043687; GO:0120147; GO:1903135 20089 FUN_005328 167 119 92 58 68 NA NA NA NA NA NA NA 20090 FUN_005329 27476 12398 6767 19729 16485 ntLink_8:34070288-34077407 Q3UZD5 1.09e-43 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 20091 FUN_005329 27476 12398 6767 19729 16485 ntLink_8:34070288-34077407 Q3UZD5 7.5e-22 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) (PR domain-containing protein in smooth muscle) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0045892; GO:0046872; GO:0051151; GO:0140944 20092 FUN_008144 12 0 6 0 21 NA NA NA NA NA NA NA 20093 FUN_029492 489 114 141 584 609 NA NA NA NA NA NA NA 20094 FUN_029493 0 0 0 32 82 NA NA NA NA NA NA NA 20095 FUN_024597 63 175 45 61 42 NA NA NA NA NA NA NA 20096 FUN_007782 721 511 294 457 0 NA NA NA NA NA NA NA 20097 FUN_007783 1305 615 954 1066 144 ptg000002l:4718120-4723175 Q7RTR2 2.03e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20098 FUN_007780 166 60 29 21 0 NA NA NA NA NA NA NA 20099 FUN_029491 6 10 0 0 14 NA NA NA NA NA NA NA 20100 FUN_007786 7941 6096 1902 3406 1533 NA NA NA NA NA NA NA 20101 FUN_007787 2301 1892 1206 1197 671 NA NA NA NA NA NA NA 20102 FUN_007784 320 191 109 448 238 NA NA NA NA NA NA NA 20103 FUN_007785 2115 1043 1140 2839 1709 NA NA NA NA NA NA NA 20104 FUN_029496 0 0 0 32 0 NA NA NA NA NA NA NA 20105 FUN_007788 1015 769 1333 1208 390 NA NA NA NA NA NA NA 20106 FUN_007789 1624 1198 623 832 583 NA NA NA NA NA NA NA 20107 FUN_027208 0 0 1 73 0 NA NA NA NA NA NA NA 20108 FUN_027201 12 0 12 2 9 NA NA NA NA NA NA NA 20109 FUN_027203 0 0 0 7 0 NA NA NA NA NA NA NA 20110 FUN_027202 16 60 9 23 32 NA NA NA NA NA NA NA 20111 FUN_027204 0 0 5 0 18 NA NA NA NA NA NA NA 20112 FUN_027207 4 0 0 55 11 NA NA NA NA NA NA NA 20113 FUN_027206 0 21 19 84 23 NA NA NA NA NA NA NA 20114 FUN_044118 0 2 11 1 88 NA NA NA NA NA NA NA 20115 FUN_044119 2 4 4 0 27 NA NA NA NA NA NA NA 20116 FUN_023600 0 25 39 73 28 NA NA NA NA NA NA NA 20117 FUN_044117 5 14 10 17 42 NA NA NA NA NA NA NA 20118 FUN_044115 3 2 10 1 82 NA NA NA NA NA NA NA 20119 FUN_044113 3 3 15 0 93 NA NA NA NA NA NA NA 20120 FUN_006789 661 372 210 590 151 NA NA NA NA NA NA NA 20121 FUN_006788 0 569 0 2 9 NA NA NA NA NA NA NA 20122 FUN_028062 7 23 77 14 43 NA NA NA NA NA NA NA 20123 FUN_008329 1398 551 640 691 951 NA NA NA NA NA NA NA 20124 FUN_008328 3810 963 2169 2195 3381 NA NA NA NA NA NA NA 20125 FUN_006781 270 155 264 437 306 ptg000001l:16481448-16483267 Q5MD89 1.89e-23 Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; hematopoietic progenitor cell differentiation [GO:0002244]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; motor neuron axon guidance [GO:0008045]; positive regulation of cell migration [GO:0030335]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of MAPK cascade [GO:0043408]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; selective angioblast sprouting [GO:0035474]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculature development [GO:0001944]; venous blood vessel development [GO:0060841]; venous endothelial cell migration involved in lymph vessel development [GO:0060855] GO:0001525; GO:0001944; GO:0001945; GO:0001946; GO:0002040; GO:0002244; GO:0004714; GO:0005021; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0007169; GO:0008045; GO:0030335; GO:0030947; GO:0033674; GO:0035474; GO:0036303; GO:0038084; GO:0042802; GO:0043235; GO:0043408; GO:0046777; GO:0048010; GO:0060836; GO:0060841; GO:0060855; GO:1900746 20126 FUN_006781 270 155 264 437 306 ptg000001l:16481448-16483267 Q5MD89 1.89e-23 Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; hematopoietic progenitor cell differentiation [GO:0002244]; lymph vessel development [GO:0001945]; lymph vessel morphogenesis [GO:0036303]; lymphangiogenesis [GO:0001946]; lymphatic endothelial cell differentiation [GO:0060836]; motor neuron axon guidance [GO:0008045]; positive regulation of cell migration [GO:0030335]; positive regulation of kinase activity [GO:0033674]; protein autophosphorylation [GO:0046777]; regulation of MAPK cascade [GO:0043408]; regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030947]; regulation of vascular endothelial growth factor signaling pathway [GO:1900746]; selective angioblast sprouting [GO:0035474]; sprouting angiogenesis [GO:0002040]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; vascular endothelial growth factor signaling pathway [GO:0038084]; vasculature development [GO:0001944]; venous blood vessel development [GO:0060841]; venous endothelial cell migration involved in lymph vessel development [GO:0060855] GO:0001525; GO:0001944; GO:0001945; GO:0001946; GO:0002040; GO:0002244; GO:0004714; GO:0005021; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0007169; GO:0008045; GO:0030335; GO:0030947; GO:0033674; GO:0035474; GO:0036303; GO:0038084; GO:0042802; GO:0043235; GO:0043408; GO:0046777; GO:0048010; GO:0060836; GO:0060841; GO:0060855; GO:1900746 20127 FUN_006780 666 156 234 498 781 NA NA NA NA NA NA NA 20128 FUN_008326 49 29 0 34 55 NA NA NA NA NA NA NA 20129 FUN_008320 24 0 70 14 194 ptg000002l:10234957-10247956 B8V7S0 4.43e-80 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 20130 FUN_008323 40 17 12 48 62 NA NA NA NA NA NA NA 20131 FUN_008322 94 20 46 134 216 NA NA NA NA NA NA NA 20132 FUN_006372 79 79 25 119 141 NA NA NA NA NA NA NA 20133 FUN_016949 0 0 27 22 10 NA NA NA NA NA NA NA 20134 FUN_016946 0 2 2 6 13 NA NA NA NA NA NA NA 20135 FUN_016947 82 5 3 0 30 NA NA NA NA NA NA NA 20136 FUN_016945 10 2 16 15 5 NA NA NA NA NA NA NA 20137 FUN_016943 0 4 0 1559 10 ptg000011l:9239516-9264162 Q95SX7 1.89e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 20138 FUN_004492 292 307 70 407 526 NA NA NA NA NA NA NA 20139 FUN_004491 867 390 372 830 549 NA NA NA NA NA NA NA 20140 FUN_003442 12 0 0 0 0 NA NA NA NA NA NA NA 20141 FUN_004496 2502 2256 1428 1409 1316 NA NA NA NA NA NA NA 20142 FUN_004499 825 758 613 798 1166 ntLink_8:23799186-23800437 Q8YFI5 5.79e-25 Na(+)/H(+) antiporter NhaA (Sodium/proton antiporter NhaA) Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) proteolysis [GO:0006508]; regulation of pH [GO:0006885] GO:0005886; GO:0006508; GO:0006885; GO:0008233; GO:0015081; GO:0015297 20143 FUN_004498 3087 3066 2929 2480 1646 NA NA NA NA NA NA NA 20144 FUN_008497 3329 3207 1787 2824 2318 NA NA NA NA NA NA NA 20145 FUN_006432 3558 3848 1581 2974 2720 NA NA NA NA NA NA NA 20146 FUN_008495 49 39 11 77 14 NA NA NA NA NA NA NA 20147 FUN_006430 407 1336 306 635 739 ptg000001l:12377136-12378761 Q6NRK8 1.13e-22 Protein THEM6 Xenopus laevis (African clawed frog) NA GO:0005576 20148 FUN_008493 568 503 390 498 315 NA NA NA NA NA NA NA 20149 FUN_006436 1383 791 781 1607 1363 ptg000001l:12414833-12424059 Q8NB14 1.65e-39 Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 20150 FUN_006436 1383 791 781 1607 1363 ptg000001l:12414833-12424059 Q8NB14 2.83e-28 Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005829; GO:0006511; GO:0016579 20151 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 0 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20152 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 1.4e-55 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20153 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 4.58e-45 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20154 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 6.02e-44 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20155 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 3.71e-42 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20156 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 1.1e-38 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20157 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 1.46e-37 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20158 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 3.48e-37 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20159 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 1.67e-36 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20160 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 3.07e-32 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20161 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 2.47e-31 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20162 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 2.97e-30 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20163 FUN_006435 1232 788 493 1202 729 ptg000001l:12400049-12405386 Q9ULJ7 2.92e-29 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 20164 FUN_006434 1372 1234 611 1730 831 NA NA NA NA NA NA NA 20165 FUN_006439 1726 1174 1609 1748 473 NA NA NA NA NA NA NA 20166 FUN_006438 1408 787 589 1124 684 ptg000001l:12442775-12446235 P29145 8.16e-89 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 20167 FUN_006438 1408 787 589 1124 684 ptg000001l:12442775-12446235 P29145 1.91e-66 PC3-like endoprotease variant B (EC 3.4.21.-) (SPC3) Hydra vulgaris (Hydra) (Hydra attenuata) proteolysis [GO:0006508] GO:0004252; GO:0006508 20168 FUN_008499 4045 1275 253 4724 3392 ptg000002l:12257573-12288242 P14543 5.8e-21 Nidogen-1 (NID-1) (Entactin) Homo sapiens (Human) basement membrane organization [GO:0071711]; cell-matrix adhesion [GO:0007160]; glomerular basement membrane development [GO:0032836]; positive regulation of cell adhesion [GO:0045785]; positive regulation of cell-substrate adhesion [GO:0010811]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; regulation of basement membrane organization [GO:0110011] GO:0005201; GO:0005509; GO:0005518; GO:0005576; GO:0005604; GO:0005886; GO:0007160; GO:0010811; GO:0032836; GO:0043236; GO:0043237; GO:0043394; GO:0045785; GO:0051149; GO:0062023; GO:0070062; GO:0071711; GO:0098637; GO:0110011; GO:2001046 20169 FUN_008498 2088 1223 992 1640 1923 NA NA NA NA NA NA NA 20170 FUN_033499 258 1075 908 1580 317 NA NA NA NA NA NA NA 20171 FUN_033491 508 190 395 535 311 ptg000023l:42439410-42441191 P22083 1.51e-45 Alpha-(1,3)-fucosyltransferase 4 (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (ELAM-1 ligand fucosyltransferase) (Fucosyltransferase 4) (Fucosyltransferase IV) (Fuc-TIV) (FucT-IV) (Galactoside 3-L-fucosyltransferase) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; inflammatory response [GO:0006954]; L-fucose catabolic process [GO:0042355]; lymphocyte migration into lymph node [GO:0097022]; oligosaccharide biosynthetic process [GO:0009312]; oligosaccharide metabolic process [GO:0009311]; positive regulation of leukocyte tethering or rolling [GO:1903238]; positive regulation of neutrophil migration [GO:1902624]; protein glycosylation [GO:0006486]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of leukocyte cell-cell adhesion [GO:1903037] GO:0000139; GO:0005794; GO:0005802; GO:0005975; GO:0006486; GO:0006487; GO:0006493; GO:0006688; GO:0006954; GO:0008417; GO:0009311; GO:0009312; GO:0009986; GO:0016020; GO:0017083; GO:0032580; GO:0036065; GO:0042355; GO:0046920; GO:0071944; GO:0097022; GO:1902624; GO:1903037; GO:1903238 20172 FUN_033492 351 293 32 208 264 NA NA NA NA NA NA NA 20173 FUN_033495 215 39 0 100 80 NA NA NA NA NA NA NA 20174 FUN_033497 642 464 137 342 541 NA NA NA NA NA NA NA 20175 FUN_033496 9 1 1 4 59 NA NA NA NA NA NA NA 20176 FUN_040344 57 0 10 70 8 NA NA NA NA NA NA NA 20177 FUN_040343 93 0 4 41 23 NA NA NA NA NA NA NA 20178 FUN_040342 159 0 38 102 78 NA NA NA NA NA NA NA 20179 FUN_004149 8 5 2 12 2 NA NA NA NA NA NA NA 20180 FUN_004148 0 0 44 122 0 NA NA NA NA NA NA NA 20181 FUN_034722 136 250 200 259 206 NA NA NA NA NA NA NA 20182 FUN_034723 6974 5765 3326 4247 3220 NA NA NA NA NA NA NA 20183 FUN_034720 2564 2237 1464 2978 2620 NA NA NA NA NA NA NA 20184 FUN_034721 3314 1487 1781 1810 1896 NA NA NA NA NA NA NA 20185 FUN_034727 4041 3418 2362 4686 4760 ptg000024l:10891149-10969335 P10394 3.22e-50 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 20186 FUN_034724 50627 64343 24784 48925 38352 ptg000024l:10857083-10873627 O16797 1.37e-67 60S ribosomal protein L3 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181]; translation [GO:0006412] GO:0002181; GO:0003723; GO:0003735; GO:0006412; GO:0022625; GO:0022626 20187 FUN_034728 0 0 17 5 54 NA NA NA NA NA NA NA 20188 FUN_016651 3630 995 1076 2513 1300 ptg000011l:5873244-5885465 Q6TMK4 3.22e-71 Peroxinectin A (EC 1.11.1.7) Dictyostelium discoideum (Social amoeba) defense response to bacterium [GO:0042742]; hydrogen peroxide catabolic process [GO:0042744]; immune response [GO:0006955]; response to oxidative stress [GO:0006979] GO:0004447; GO:0004601; GO:0005576; GO:0005783; GO:0006955; GO:0006979; GO:0020037; GO:0036393; GO:0042742; GO:0042744; GO:0140825 20189 FUN_020978 0 0 0 0 11 NA NA NA NA NA NA NA 20190 FUN_020979 0 0 0 0 42 NA NA NA NA NA NA NA 20191 FUN_023606 9 0 0 0 3 NA NA NA NA NA NA NA 20192 FUN_015981 694 442 558 750 865 NA NA NA NA NA NA NA 20193 FUN_002793 0 0 2 0 134 NA NA NA NA NA NA NA 20194 FUN_008381 450 280 243 359 246 NA NA NA NA NA NA NA 20195 FUN_016657 240 221 294 225 241 ptg000011l:6015778-6019002 Q5PPN7 5.18e-37 Mitochondrial potassium channel (MITOK) (Coiled-coil domain-containing protein 51) Rattus norvegicus (Rat) cell volume homeostasis [GO:0006884]; mitochondrial potassium ion transmembrane transport [GO:0140141]; potassium ion transmembrane transport [GO:0071805] GO:0005743; GO:0006884; GO:0034705; GO:0062156; GO:0062157; GO:0071805; GO:0140141 20196 FUN_002799 6 135 0 19 0 NA NA NA NA NA NA NA 20197 FUN_034950 135 123 53 95 145 ptg000025l:2032291-2034416 Q1LU86 1.77e-49 CBY1-interacting BAR domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; inner mitochondrial membrane organization [GO:0007007]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005634; GO:0005737; GO:0005743; GO:0005814; GO:0005929; GO:0007007; GO:0019898; GO:0035869; GO:0036064; GO:0045880; GO:0060271; GO:0097546 20198 FUN_015987 136 195 361 331 145 NA NA NA NA NA NA NA 20199 FUN_002428 329 31 77 858 177 NA NA NA NA NA NA NA 20200 FUN_002429 1549 1026 829 1360 888 NA NA NA NA NA NA NA 20201 FUN_002841 0 15 40 3 73 NA NA NA NA NA NA NA 20202 FUN_002420 0 4 22 2 2 NA NA NA NA NA NA NA 20203 FUN_002421 0 6 10 4 4 NA NA NA NA NA NA NA 20204 FUN_002422 0 0 17 0 0 NA NA NA NA NA NA NA 20205 FUN_002424 260 372 25 55 19 ntLink_8:1340182-1442700 Q09575 3.06e-22 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 20206 FUN_002424 260 372 25 55 19 ntLink_8:1340182-1442700 Q09575 3.06e-22 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 20207 FUN_002425 208 341 111 169 99 NA NA NA NA NA NA NA 20208 FUN_011734 55 18 14 41 22 NA NA NA NA NA NA NA 20209 FUN_011735 1497 968 245 946 571 NA NA NA NA NA NA NA 20210 FUN_011736 2241 1215 1295 2614 2353 ptg000008l:764253-776535 P19111 1.74e-22 Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1) Bos taurus (Bovine) dephosphorylation [GO:0016311] GO:0000287; GO:0004035; GO:0005886; GO:0008270; GO:0016311 20211 FUN_011737 1366 630 473 772 1055 ptg000008l:779453-790331 Q09916 1.14e-25 ATP-dependent RNA helicase has1 (EC 3.6.4.13) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463] GO:0000463; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0016887 20212 FUN_011730 81 97 135 168 106 ptg000008l:679462-681031 B0UYT5 1.71e-30 Major facilitator superfamily domain-containing protein 6-B (Macrophage MHC class I receptor 2 homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 20213 FUN_011731 2115 1684 1211 1551 1063 NA NA NA NA NA NA NA 20214 FUN_000499 1471 696 916 1138 1096 ntLink_6:3686346-3698035 Q9Z0X4 1.13e-22 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) Mus musculus (Mouse) apoptotic signaling pathway [GO:0097190]; cAMP-mediated signaling [GO:0019933]; cellular response to cGMP [GO:0071321]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP-mediated signaling [GO:0019934]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of vascular permeability [GO:0043116]; oocyte development [GO:0048599]; oocyte maturation [GO:0001556]; positive regulation of oocyte development [GO:0060282]; positive regulation of vascular permeability [GO:0043117]; regulation of meiotic nuclear division [GO:0040020]; regulation of ribonuclease activity [GO:0060700]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165] GO:0001556; GO:0004114; GO:0004115; GO:0004119; GO:0005829; GO:0007165; GO:0009410; GO:0016020; GO:0019933; GO:0019934; GO:0040020; GO:0043066; GO:0043116; GO:0043117; GO:0043951; GO:0046872; GO:0047555; GO:0048599; GO:0060282; GO:0060700; GO:0071321; GO:0071560; GO:0097190; GO:0099130 20215 FUN_011733 1764 1347 1193 1743 1742 NA NA NA NA NA NA NA 20216 FUN_000497 191 44 17 22 14 ntLink_6:3665067-3666432 Q4R683 1.57e-29 Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) DNA cytosine deamination [GO:0070383] GO:0004126; GO:0005634; GO:0005737; GO:0008270; GO:0042803; GO:0061676; GO:0070383 20217 FUN_000496 244 332 233 163 265 ntLink_6:3655883-3657193 Q4R683 5.39e-31 Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) DNA cytosine deamination [GO:0070383] GO:0004126; GO:0005634; GO:0005737; GO:0008270; GO:0042803; GO:0061676; GO:0070383 20218 FUN_000494 309 508 182 153 301 ntLink_6:3634396-3636391 Q4R683 1.62e-30 Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) DNA cytosine deamination [GO:0070383] GO:0004126; GO:0005634; GO:0005737; GO:0008270; GO:0042803; GO:0061676; GO:0070383 20219 FUN_011738 236 188 128 179 136 NA NA NA NA NA NA NA 20220 FUN_000491 79 26 0 80 7 ntLink_6:3619168-3621309 Q5U3U4 1.47e-23 Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0004126; GO:0008270 20221 FUN_000490 2052 2584 953 1600 814 NA NA NA NA NA NA NA 20222 FUN_035893 86 39 53 117 100 ptg000025l:13056478-13059304 Q98982 2.23e-25 Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1) Lithobates catesbeianus (American bullfrog) (Rana catesbeiana) NA GO:0004995; GO:0005886 20223 FUN_035892 3256 2671 2333 3005 1846 NA NA NA NA NA NA NA 20224 FUN_035891 4374 4282 1958 2972 1975 ptg000025l:13013905-13025397 Q9WUU6 7.25e-41 Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2) Mus musculus (Mouse) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0004879; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0008270; GO:0030154; GO:0045171; GO:0045893; GO:0045944; GO:0048856; GO:0072686 20225 FUN_035891 4374 4282 1958 2972 1975 ptg000025l:13013905-13025397 Q9WUU6 1.55e-34 Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2) Mus musculus (Mouse) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0004879; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0008270; GO:0030154; GO:0045171; GO:0045893; GO:0045944; GO:0048856; GO:0072686 20226 FUN_035891 4374 4282 1958 2972 1975 ptg000025l:13013905-13025397 Q9WUU6 4.77e-25 Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2) Mus musculus (Mouse) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0004879; GO:0005654; GO:0005667; GO:0005829; GO:0006357; GO:0008270; GO:0030154; GO:0045171; GO:0045893; GO:0045944; GO:0048856; GO:0072686 20227 FUN_035890 2402 1316 600 1567 1121 NA NA NA NA NA NA NA 20228 FUN_035897 1362 1007 530 921 994 NA NA NA NA NA NA NA 20229 FUN_035896 2088 1281 1620 2204 2420 NA NA NA NA NA NA NA 20230 FUN_035895 2446 1533 994 1791 1000 ptg000025l:13068030-13073027 Q1JPG1 2.81e-71 Radial spoke head 10 homolog B Bos taurus (Bovine) NA NA 20231 FUN_035895 2446 1533 994 1791 1000 ptg000025l:13068030-13073027 Q1JPG1 6.09e-44 Radial spoke head 10 homolog B Bos taurus (Bovine) NA NA 20232 FUN_035894 845 484 480 636 522 NA NA NA NA NA NA NA 20233 FUN_041570 370 260 264 257 177 NA NA NA NA NA NA NA 20234 FUN_035899 467 483 374 364 471 NA NA NA NA NA NA NA 20235 FUN_035898 2283 1310 966 1230 1134 NA NA NA NA NA NA NA 20236 FUN_000233 395 368 411 244 309 NA NA NA NA NA NA NA 20237 FUN_029342 5006 4575 2517 4073 2319 NA NA NA NA NA NA NA 20238 FUN_029343 1249 1098 493 885 735 NA NA NA NA NA NA NA 20239 FUN_029340 2682 1965 1269 2688 1529 NA NA NA NA NA NA NA 20240 FUN_029341 583 178 177 356 572 NA NA NA NA NA NA NA 20241 FUN_029346 85 186 111 381 94 NA NA NA NA NA NA NA 20242 FUN_029347 0 0 1 9 0 NA NA NA NA NA NA NA 20243 FUN_029344 746 243 316 748 1013 NA NA NA NA NA NA NA 20244 FUN_029345 1757 1243 781 1469 1246 ptg000023l:829576-837422 Q640B3 6.66e-23 5'-3' exonuclease PLD3 (EC 3.1.16.1) (Choline phosphatase 3) (Phosphatidylcholine-hydrolyzing phospholipase D3) (Phospholipase D3) (PLD 3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) immune system process [GO:0002376]; inflammatory response [GO:0006954]; myotube differentiation [GO:0014902]; regulation of cytokine production involved in inflammatory response [GO:1900015] GO:0000139; GO:0002376; GO:0005789; GO:0006954; GO:0014902; GO:0031901; GO:0031902; GO:0043202; GO:0045145; GO:1900015 20245 FUN_029348 462 0 71 32 4 NA NA NA NA NA NA NA 20246 FUN_000232 1912 1509 807 1052 1629 NA NA NA NA NA NA NA 20247 FUN_004795 4511 2960 2528 4429 3736 NA NA NA NA NA NA NA 20248 FUN_000231 5023 2569 2441 4837 4068 NA NA NA NA NA NA NA 20249 FUN_031673 11 64 53 201 74 NA NA NA NA NA NA NA 20250 FUN_029694 5 12 8 9 3 NA NA NA NA NA NA NA 20251 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 1.36e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20252 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 1.57e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20253 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 1.62e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20254 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 2.41e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20255 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 2.23e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20256 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 1.02e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20257 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 9.49e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20258 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 1.23e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20259 FUN_029696 163 144 47 215 98 ptg000023l:4633643-4639324 Q96AY4 1.98e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20260 FUN_029697 0 0 12 28 18 NA NA NA NA NA NA NA 20261 FUN_029690 117 19 9 19 31 ptg000023l:4550032-4552253 E7FAM5 5.21e-47 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20262 FUN_029691 83 39 51 14 230 ptg000023l:4565940-4571896 Q96AY4 3.03e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20263 FUN_029691 83 39 51 14 230 ptg000023l:4565940-4571896 Q96AY4 4.72e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20264 FUN_029691 83 39 51 14 230 ptg000023l:4565940-4571896 Q96AY4 8.14e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20265 FUN_029691 83 39 51 14 230 ptg000023l:4565940-4571896 Q96AY4 1.03e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20266 FUN_029691 83 39 51 14 230 ptg000023l:4565940-4571896 Q96AY4 4.14e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20267 FUN_029691 83 39 51 14 230 ptg000023l:4565940-4571896 Q96AY4 1.67e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20268 FUN_029692 8 0 7 2 9 NA NA NA NA NA NA NA 20269 FUN_029693 0 0 45 0 0 ptg000023l:4585136-4587068 E1BD59 1.12e-21 E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (Tripartite motif-containing protein 56) Bos taurus (Bovine) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340] GO:0000785; GO:0004842; GO:0005654; GO:0005737; GO:0008270; GO:0032728; GO:0034340; GO:0045087; GO:0045893; GO:0051607; GO:0061630; GO:0070534 20270 FUN_029699 267 251 61 279 232 ptg000023l:4663097-4676112 Q96AY4 3.17e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20271 FUN_029699 267 251 61 279 232 ptg000023l:4663097-4676112 Q96AY4 1.87e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20272 FUN_029699 267 251 61 279 232 ptg000023l:4663097-4676112 Q96AY4 2.26e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20273 FUN_000230 305 285 283 244 361 ntLink_6:542058-548872 Q5VTE6 7.14e-35 Protein angel homolog 2 Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; negative regulation of mitotic cell cycle [GO:0045930] GO:0000175; GO:0003730; GO:0005737; GO:0015030; GO:0045930; GO:0070935 20274 FUN_013466 61 0 9 207 9 ptg000008l:22978958-22979653 P0C0R5 1.39e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 20275 FUN_013467 228 15 19 362 98 NA NA NA NA NA NA NA 20276 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 2.39e-79 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20277 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 7.55e-75 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20278 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 2.5e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20279 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 8.34e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20280 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 3.99e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20281 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 1.13e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20282 FUN_013464 463 4174 1903 3069 97 ptg000008l:22866035-22965200 Q7RTR2 9.62e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20283 FUN_013465 79 164 56 210 50 NA NA NA NA NA NA NA 20284 FUN_013462 33 129 186 59 0 NA NA NA NA NA NA NA 20285 FUN_013463 18 90 48 32 0 NA NA NA NA NA NA NA 20286 FUN_013460 0 0 0 23 0 NA NA NA NA NA NA NA 20287 FUN_013461 74 33 53 0 0 NA NA NA NA NA NA NA 20288 FUN_015709 14 24 8 9 0 NA NA NA NA NA NA NA 20289 FUN_043702 8 0 0 0 35 NA NA NA NA NA NA NA 20290 FUN_015701 3 3 0 10 7 NA NA NA NA NA NA NA 20291 FUN_043705 0 0 0 0 78 NA NA NA NA NA NA NA 20292 FUN_016177 9 45 86 20 34 NA NA NA NA NA NA NA 20293 FUN_016175 1 3 19 13 61 NA NA NA NA NA NA NA 20294 FUN_016173 67 146 143 155 412 NA NA NA NA NA NA NA 20295 FUN_016172 5 5 16 2 108 NA NA NA NA NA NA NA 20296 FUN_042251 89 354 118 381 232 NA NA NA NA NA NA NA 20297 FUN_023061 663 229 139 145 366 NA NA NA NA NA NA NA 20298 FUN_023063 1504 1360 679 355 1343 ptg000017l:3126094-3133973 Q66L33 1.63e-22 Protein MAK16 homolog A (MAK16-like protein A) Xenopus laevis (African clawed frog) NA GO:0005730 20299 FUN_023062 1000 809 537 632 344 NA NA NA NA NA NA NA 20300 FUN_023064 2416 1584 1139 1829 2121 NA NA NA NA NA NA NA 20301 FUN_023066 2250 1638 1761 2685 1868 NA NA NA NA NA NA NA 20302 FUN_036813 14 0 0 0 0 NA NA NA NA NA NA NA 20303 FUN_036810 1676 946 1034 1776 1340 NA NA NA NA NA NA NA 20304 FUN_036811 0 0 7 0 18 NA NA NA NA NA NA NA 20305 FUN_036816 20 0 10 0 0 NA NA NA NA NA NA NA 20306 FUN_036817 169 30 120 418 351 ptg000026l:2216214-2238092 Q9R0M0 8.35e-47 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 20307 FUN_036817 169 30 120 418 351 ptg000026l:2216214-2238092 Q9R0M0 4.28e-43 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 20308 FUN_036817 169 30 120 418 351 ptg000026l:2216214-2238092 Q9R0M0 1.02e-35 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 20309 FUN_036817 169 30 120 418 351 ptg000026l:2216214-2238092 Q9R0M0 1.11e-32 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 20310 FUN_036817 169 30 120 418 351 ptg000026l:2216214-2238092 Q9R0M0 2.39e-31 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 20311 FUN_036815 0 11 65 42 112 NA NA NA NA NA NA NA 20312 FUN_008869 377 1190 345 423 1362 NA NA NA NA NA NA NA 20313 FUN_008866 0 0 0 0 36 NA NA NA NA NA NA NA 20314 FUN_008867 284 271 218 78 515 NA NA NA NA NA NA NA 20315 FUN_008864 48 112 98 110 285 NA NA NA NA NA NA NA 20316 FUN_008865 30 45 0 0 111 NA NA NA NA NA NA NA 20317 FUN_008862 6 4 13 3 116 NA NA NA NA NA NA NA 20318 FUN_008860 2614 1507 1129 2148 1920 ptg000002l:16110318-16125936 Q96M96 1.26e-26 FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament-binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cytoskeleton organization [GO:0007010]; filopodium assembly [GO:0046847]; regulation of cell shape [GO:0008360]; regulation of GTPase activity [GO:0043087]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0001726; GO:0003779; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0007010; GO:0008360; GO:0030027; GO:0030036; GO:0030175; GO:0031267; GO:0043087; GO:0046847; GO:0046872; GO:0051056 20319 FUN_008861 0 14 0 11 9 NA NA NA NA NA NA NA 20320 FUN_013289 45 74 0 0 29 NA NA NA NA NA NA NA 20321 FUN_013283 17 121 119 128 141 NA NA NA NA NA NA NA 20322 FUN_013287 312 297 74 25 170 ptg000008l:20510756-20512688 Q0V8L6 1.03e-127 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 20323 FUN_028565 13 5 3 62 5 NA NA NA NA NA NA NA 20324 FUN_028564 16 12 22 38 2 NA NA NA NA NA NA NA 20325 FUN_028561 81 40 137 71 50 NA NA NA NA NA NA NA 20326 FUN_028560 0 16 10 0 0 ptg000022l:704178-705401 Q3UFF7 4.17e-22 Lysophospholipase-like protein 1 (EC 3.1.2.22) Mus musculus (Mouse) negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; protein depalmitoylation [GO:0002084] GO:0002084; GO:0005737; GO:0005829; GO:0008474; GO:0042997 20327 FUN_028563 43 0 15 18 5 ptg000022l:721063-726996 Q96AY4 3.04e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20328 FUN_028563 43 0 15 18 5 ptg000022l:721063-726996 Q96AY4 9.58e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20329 FUN_028563 43 0 15 18 5 ptg000022l:721063-726996 Q96AY4 1.44e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20330 FUN_028563 43 0 15 18 5 ptg000022l:721063-726996 Q96AY4 5.02e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20331 FUN_028563 43 0 15 18 5 ptg000022l:721063-726996 Q96AY4 1.57e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20332 FUN_028563 43 0 15 18 5 ptg000022l:721063-726996 Q96AY4 1.82e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20333 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 3.01e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20334 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 5.38e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20335 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 7.71e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20336 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 8.49e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20337 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 1.27e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20338 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 3.27e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20339 FUN_028562 1 0 2 6 1 ptg000022l:718791-720759 Q96AY4 2.67e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20340 FUN_027902 2883 1615 1246 1906 1306 ptg000021l:12885463-12896348 Q8CAL5 2.01e-23 Glypican-5 [Cleaved into: Secreted glypican-5] Mus musculus (Mouse) cell migration [GO:0016477]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of protein localization to membrane [GO:1905475] GO:0005615; GO:0005796; GO:0005886; GO:0009986; GO:0016477; GO:0062023; GO:0090263; GO:1905475 20341 FUN_041638 2011 1160 1119 1897 1909 NA NA NA NA NA NA NA 20342 FUN_041639 1695 1636 578 648 782 NA NA NA NA NA NA NA 20343 FUN_041634 40578 27576 24193 38028 19390 ptg000035l:6073509-6082850 P57059 2.1e-24 Serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (Salt-inducible kinase 1) (SIK-1) (Serine/threonine-protein kinase SNF1-like kinase 1) (Serine/threonine-protein kinase SNF1LK) Homo sapiens (Human) anoikis [GO:0043276]; cardiac muscle cell differentiation [GO:0055007]; cell cycle [GO:0007049]; cellular response to glucose starvation [GO:0042149]; entrainment of circadian clock by photoperiod [GO:0043153]; intracellular signal transduction [GO:0035556]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of gluconeogenesis [GO:0045721]; negative regulation of triglyceride biosynthetic process [GO:0010868]; positive regulation of anoikis [GO:2000210]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell differentiation [GO:0045595]; regulation of mitotic cell cycle [GO:0007346]; regulation of myotube differentiation [GO:0010830]; regulation of sodium ion transport [GO:0002028]; rhythmic process [GO:0048511] GO:0000287; GO:0002028; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0007049; GO:0007346; GO:0008140; GO:0010830; GO:0010868; GO:0019901; GO:0032792; GO:0035556; GO:0042149; GO:0042826; GO:0043153; GO:0043276; GO:0045595; GO:0045721; GO:0046777; GO:0048511; GO:0055007; GO:0071889; GO:0106310; GO:2000210 20344 FUN_041635 1985 1892 655 1244 1115 NA NA NA NA NA NA NA 20345 FUN_041636 531 239 233 297 276 NA NA NA NA NA NA NA 20346 FUN_041637 115 117 68 96 145 NA NA NA NA NA NA NA 20347 FUN_041630 2080 1929 1477 2182 2363 ptg000035l:6050812-6054189 Q6P825 5.68e-60 Mitochondrial import receptor subunit TOM40 homolog (Translocase of outer membrane 40 kDa subunit homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) ion transport [GO:0006811]; protein import into mitochondrial matrix [GO:0030150]; protein targeting to mitochondrion [GO:0006626] GO:0005741; GO:0006626; GO:0006811; GO:0008320; GO:0015288; GO:0030150; GO:0046930 20348 FUN_041631 1725 1719 999 1255 1653 NA NA NA NA NA NA NA 20349 FUN_041632 487 175 210 428 451 NA NA NA NA NA NA NA 20350 FUN_041633 577 671 686 1492 637 NA NA NA NA NA NA NA 20351 FUN_000574 699 756 571 1133 1000 NA NA NA NA NA NA NA 20352 FUN_014159 60 0 3 0 28 NA NA NA NA NA NA NA 20353 FUN_014153 7 0 0 0 0 NA NA NA NA NA NA NA 20354 FUN_014152 0 0 0 14 0 NA NA NA NA NA NA NA 20355 FUN_000575 49 120 101 90 99 NA NA NA NA NA NA NA 20356 FUN_022009 0 7 0 0 0 NA NA NA NA NA NA NA 20357 FUN_025058 0 0 0 0 16 NA NA NA NA NA NA NA 20358 FUN_022003 21 5 26 5 56 NA NA NA NA NA NA NA 20359 FUN_022004 3042 5350 2641 2956 1551 NA NA NA NA NA NA NA 20360 FUN_022005 0 6 2 4 19 NA NA NA NA NA NA NA 20361 FUN_022007 4 0 574 0 474 NA NA NA NA NA NA NA 20362 FUN_043205 2809 1544 1130 1502 1303 NA NA NA NA NA NA NA 20363 FUN_042006 72 38 19 0 54 NA NA NA NA NA NA NA 20364 FUN_024090 2550 2216 2213 2134 739 NA NA NA NA NA NA NA 20365 FUN_042005 364 340 278 361 342 NA NA NA NA NA NA NA 20366 FUN_024095 10 0 0 0 0 NA NA NA NA NA NA NA 20367 FUN_024094 26 15 0 0 4 NA NA NA NA NA NA NA 20368 FUN_024097 215 307 122 257 419 NA NA NA NA NA NA NA 20369 FUN_024096 631 143 244 462 262 NA NA NA NA NA NA NA 20370 FUN_024099 538 173 248 391 317 NA NA NA NA NA NA NA 20371 FUN_024098 3 6 0 0 0 NA NA NA NA NA NA NA 20372 FUN_042003 0 0 0 0 14 NA NA NA NA NA NA NA 20373 FUN_006202 124 14 44 262 163 ptg000001l:9158822-9167397 Q7RTR2 6.54e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20374 FUN_006202 124 14 44 262 163 ptg000001l:9158822-9167397 Q7RTR2 3.41e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20375 FUN_006202 124 14 44 262 163 ptg000001l:9158822-9167397 Q7RTR2 4.71e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20376 FUN_006202 124 14 44 262 163 ptg000001l:9158822-9167397 Q7RTR2 1.36e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20377 FUN_006203 0 0 0 19 4 NA NA NA NA NA NA NA 20378 FUN_015288 275 99 100 331 469 ptg000009l:8469484-8472140 O15439 2.33e-78 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20379 FUN_015288 275 99 100 331 469 ptg000009l:8469484-8472140 O15439 3.19e-30 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20380 FUN_015289 61 21 2 8 21 NA NA NA NA NA NA NA 20381 FUN_015280 160 67 185 185 288 NA NA NA NA NA NA NA 20382 FUN_015281 4 12 9 17 14 NA NA NA NA NA NA NA 20383 FUN_015282 1138 741 472 1216 813 ptg000009l:8344631-8415426 O60290 8.81e-84 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 20384 FUN_015283 4 17 12 20 89 NA NA NA NA NA NA NA 20385 FUN_015284 860 147 234 463 309 ptg000009l:8428854-8454184 O15439 7.15e-81 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20386 FUN_015284 860 147 234 463 309 ptg000009l:8428854-8454184 O15439 6.7e-78 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20387 FUN_015284 860 147 234 463 309 ptg000009l:8428854-8454184 O15439 2.16e-49 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20388 FUN_015284 860 147 234 463 309 ptg000009l:8428854-8454184 O15439 2.55e-48 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20389 FUN_015284 860 147 234 463 309 ptg000009l:8428854-8454184 O15439 3.08e-31 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20390 FUN_015284 860 147 234 463 309 ptg000009l:8428854-8454184 O15439 6.01e-31 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 20391 FUN_015285 38 25 13 61 39 NA NA NA NA NA NA NA 20392 FUN_015286 33 13 17 74 98 NA NA NA NA NA NA NA 20393 FUN_015287 113 79 80 113 234 ptg000009l:8466571-8469060 Q54JR2 1.08e-57 ABC transporter C family member 3 (ABC transporter ABCC.3) Dictyostelium discoideum (Social amoeba) culmination involved in sorocarp development [GO:0031154]; transmembrane transport [GO:0055085] GO:0005524; GO:0016020; GO:0016887; GO:0031154; GO:0042626; GO:0055085; GO:0140359 20394 FUN_016862 13 0 0 10 8 NA NA NA NA NA NA NA 20395 FUN_023843 0 0 0 0 6 NA NA NA NA NA NA NA 20396 FUN_031725 2533 1759 1220 2280 1571 ptg000023l:24798714-24810398 Q6IN85 7.27e-70 Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; protein dephosphorylation [GO:0006470] GO:0005654; GO:0005815; GO:0005829; GO:0006470; GO:0006974; GO:0016607; GO:0030289; GO:0072542 20397 FUN_031725 2533 1759 1220 2280 1571 ptg000023l:24798714-24810398 Q6IN85 1.33e-36 Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; protein dephosphorylation [GO:0006470] GO:0005654; GO:0005815; GO:0005829; GO:0006470; GO:0006974; GO:0016607; GO:0030289; GO:0072542 20398 FUN_031725 2533 1759 1220 2280 1571 ptg000023l:24798714-24810398 Q6IN85 1.33e-36 Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; protein dephosphorylation [GO:0006470] GO:0005654; GO:0005815; GO:0005829; GO:0006470; GO:0006974; GO:0016607; GO:0030289; GO:0072542 20399 FUN_031724 4771 7143 2890 5015 3591 NA NA NA NA NA NA NA 20400 FUN_031727 179 96 56 265 130 NA NA NA NA NA NA NA 20401 FUN_031726 2627 2636 1495 2419 2905 NA NA NA NA NA NA NA 20402 FUN_031721 83 35 13 108 62 NA NA NA NA NA NA NA 20403 FUN_031720 253 200 147 455 322 NA NA NA NA NA NA NA 20404 FUN_031723 90 178 113 121 240 ptg000023l:24742248-24746291 Q8BH86 1.75e-24 D-glutamate cyclase, mitochondrial (EC 4.2.1.48) Mus musculus (Mouse) glutamate metabolic process [GO:0006536] GO:0005739; GO:0005759; GO:0006536; GO:0047820 20405 FUN_031722 35 0 0 57 43 NA NA NA NA NA NA NA 20406 FUN_039537 0 13 0 0 4 NA NA NA NA NA NA NA 20407 FUN_039538 0 0 22 46 68 NA NA NA NA NA NA NA 20408 FUN_039539 0 0 0 10 0 NA NA NA NA NA NA NA 20409 FUN_031096 0 98 0 0 0 ptg000023l:17303816-17304592 B8VIU6 1.87e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 20410 FUN_031095 25 48 42 46 196 NA NA NA NA NA NA NA 20411 FUN_031094 0 0 0 0 13 NA NA NA NA NA NA NA 20412 FUN_031093 9 79 49 83 88 ptg000023l:17266562-17274727 B8VIU6 1.02e-33 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 20413 FUN_031092 39 17 37 65 167 ptg000023l:17252257-17263982 B8VIU6 5.6e-33 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 20414 FUN_017732 2 0 9 3 24 NA NA NA NA NA NA NA 20415 FUN_018501 71 78 64 119 0 NA NA NA NA NA NA NA 20416 FUN_026930 34 0 0 0 0 NA NA NA NA NA NA NA 20417 FUN_026931 21 0 0 0 0 NA NA NA NA NA NA NA 20418 FUN_026937 0 1 18 0 27 NA NA NA NA NA NA NA 20419 FUN_026938 0 57 147 39 143 NA NA NA NA NA NA NA 20420 FUN_018504 642 1084 310 1164 1089 NA NA NA NA NA NA NA 20421 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 2.45e-42 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20422 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 5.23e-39 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20423 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 9.12e-39 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20424 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 1.07e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20425 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 1.63e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20426 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 1.04e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20427 FUN_039398 1 0 107 1 153 ptg000029c:1354971-1355772 Q5DU56 1.37e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20428 FUN_039399 44 0 0 51 41 NA NA NA NA NA NA NA 20429 FUN_039394 93 0 22 0 38 NA NA NA NA NA NA NA 20430 FUN_039395 0 0 0 0 15 NA NA NA NA NA NA NA 20431 FUN_039396 1248 7 25 1280 408 NA NA NA NA NA NA NA 20432 FUN_039397 0 0 3 0 26 NA NA NA NA NA NA NA 20433 FUN_039390 202 21 12 88 0 ptg000029c:1161417-1173504 Q7RTR2 3.18e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20434 FUN_039390 202 21 12 88 0 ptg000029c:1161417-1173504 Q7RTR2 2.02e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20435 FUN_039390 202 21 12 88 0 ptg000029c:1161417-1173504 Q7RTR2 2.67e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20436 FUN_039390 202 21 12 88 0 ptg000029c:1161417-1173504 Q7RTR2 1.73e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20437 FUN_039390 202 21 12 88 0 ptg000029c:1161417-1173504 Q7RTR2 2.26e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20438 FUN_039391 1054 23 96 1223 267 ptg000029c:1209449-1221752 Q7RTR2 4.45e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20439 FUN_039391 1054 23 96 1223 267 ptg000029c:1209449-1221752 Q7RTR2 1.39e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20440 FUN_039391 1054 23 96 1223 267 ptg000029c:1209449-1221752 Q7RTR2 3.4e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20441 FUN_039391 1054 23 96 1223 267 ptg000029c:1209449-1221752 Q7RTR2 1.08e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20442 FUN_039391 1054 23 96 1223 267 ptg000029c:1209449-1221752 Q7RTR2 4.9e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20443 FUN_039391 1054 23 96 1223 267 ptg000029c:1209449-1221752 Q7RTR2 3.52e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20444 FUN_039392 0 0 0 0 36 NA NA NA NA NA NA NA 20445 FUN_038317 14 0 11 0 7 NA NA NA NA NA NA NA 20446 FUN_035601 855 362 392 753 589 NA NA NA NA NA NA NA 20447 FUN_018013 2248 1482 1146 1881 1519 ptg000012l:3280773-3295222 Q5ZJM3 3.28e-38 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Gallus gallus (Chicken) glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872 20448 FUN_031991 24 10 24 55 151 NA NA NA NA NA NA NA 20449 FUN_006200 32 366 0 6 100 NA NA NA NA NA NA NA 20450 FUN_006815 0 13 23 130 60 NA NA NA NA NA NA NA 20451 FUN_006817 17 32 67 204 177 NA NA NA NA NA NA NA 20452 FUN_006816 0 0 14 69 42 NA NA NA NA NA NA NA 20453 FUN_036120 825 351 29 331 131 NA NA NA NA NA NA NA 20454 FUN_006811 33 38 39 102 122 NA NA NA NA NA NA NA 20455 FUN_003456 77 0 0 0 0 NA NA NA NA NA NA NA 20456 FUN_006579 85 90 15 135 30 ptg000001l:14341257-14342343 Q6BD04 3.15e-24 G-protein coupled receptor 54 Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) NA GO:0004930; GO:0005886 20457 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 1.12e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20458 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 2.1e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20459 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 2.53e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20460 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 3.41e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20461 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 2.89e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20462 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 4.79e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20463 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 5.46e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20464 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 1.43e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20465 FUN_016532 55 61 58 101 168 ptg000011l:4441231-4447469 Q96AY4 6.51e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20466 FUN_026066 134 432 176 60 1429 NA NA NA NA NA NA NA 20467 FUN_026067 92 135 124 49 354 NA NA NA NA NA NA NA 20468 FUN_026064 287 4 175 220 0 NA NA NA NA NA NA NA 20469 FUN_026065 10470 10285 7919 14680 7418 NA NA NA NA NA NA NA 20470 FUN_026062 0 0 63 7 0 NA NA NA NA NA NA NA 20471 FUN_026063 538 145 121 127 247 ptg000020l:4248313-4252564 Q7RTR2 3.22e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20472 FUN_026060 790 135 365 709 557 ptg000020l:4216792-4221114 Q7RTR2 2.16e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20473 FUN_026061 0 0 6 28 7 NA NA NA NA NA NA NA 20474 FUN_006812 262 438 4369 889 14611 NA NA NA NA NA NA NA 20475 FUN_026068 439 506 927 218 497 NA NA NA NA NA NA NA 20476 FUN_026069 310 586 253 375 401 NA NA NA NA NA NA NA 20477 FUN_003457 850 2729 171 2528 1177 NA NA NA NA NA NA NA 20478 FUN_028542 18 4 68 11 160 NA NA NA NA NA NA NA 20479 FUN_004620 1662 1143 514 887 563 ntLink_8:24939919-24950181 Q6NUT3 8.75e-49 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 20480 FUN_004621 163 24 11 133 90 NA NA NA NA NA NA NA 20481 FUN_004622 676 552 881 956 837 NA NA NA NA NA NA NA 20482 FUN_004309 27 51 7 9 4 NA NA NA NA NA NA NA 20483 FUN_004308 2195 3573 1797 1915 1747 NA NA NA NA NA NA NA 20484 FUN_004303 1478 961 593 1130 886 ntLink_8:21707412-21713559 Q9CZR2 7.43e-33 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 20485 FUN_004303 1478 961 593 1130 886 ntLink_8:21707412-21713559 Q9CZR2 7.76e-28 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 20486 FUN_004302 1257 1168 560 1260 1247 ntLink_8:21681056-21706262 P50533 2.55e-31 Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome condensation [GO:0030261] GO:0005524; GO:0005634; GO:0005694; GO:0005829; GO:0007049; GO:0016887; GO:0030261; GO:0051301 20487 FUN_004302 1257 1168 560 1260 1247 ntLink_8:21681056-21706262 P50533 1.21e-22 Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome assembly protein XCAP-E) (Chromosome-associated protein E) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; chromosome condensation [GO:0030261] GO:0005524; GO:0005634; GO:0005694; GO:0005829; GO:0007049; GO:0016887; GO:0030261; GO:0051301 20488 FUN_004301 31 24 77 68 90 ntLink_8:21675882-21677049 P11023 2.03e-39 Ras-related protein Rab-3A (SMG P25A) Bos taurus (Bovine) axonogenesis [GO:0007409]; calcium-ion regulated exocytosis [GO:0017156]; lung development [GO:0030324]; maintenance of presynaptic active zone structure [GO:0048790]; mitochondrion organization [GO:0007005]; neuromuscular synaptic transmission [GO:0007274]; post-embryonic development [GO:0009791]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; respiratory system process [GO:0003016]; response to electrical stimulus [GO:0051602]; sensory perception of touch [GO:0050975]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904] GO:0003016; GO:0003924; GO:0005525; GO:0005764; GO:0005768; GO:0005829; GO:0005886; GO:0006904; GO:0007005; GO:0007274; GO:0007409; GO:0008021; GO:0009306; GO:0009791; GO:0016020; GO:0016079; GO:0016188; GO:0017156; GO:0017157; GO:0030324; GO:0030424; GO:0030672; GO:0031489; GO:0031630; GO:0043231; GO:0048786; GO:0048790; GO:0050975; GO:0051602; GO:0072659; GO:0098793; GO:0098794 20489 FUN_004300 0 0 0 0 8 ntLink_8:21672865-21673982 Q96E17 2.48e-38 Ras-related protein Rab-3C Homo sapiens (Human) antigen processing and presentation [GO:0019882]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904] GO:0003924; GO:0005525; GO:0005768; GO:0005829; GO:0005886; GO:0006904; GO:0008021; GO:0009306; GO:0017157; GO:0019882; GO:0030672; GO:0030742; GO:0031489; GO:0031982; GO:0043231; GO:0048471; GO:0072659 20490 FUN_004307 6701 40669 10529 23847 19236 NA NA NA NA NA NA NA 20491 FUN_004306 4165 3537 3285 4883 2801 NA NA NA NA NA NA NA 20492 FUN_004305 3469 1266 1020 1888 1447 ntLink_8:21731839-21738349 Q9CZR2 7.75e-33 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 20493 FUN_004305 3469 1266 1020 1888 1447 ntLink_8:21731839-21738349 Q9CZR2 3.7e-23 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 20494 FUN_004304 3463 3045 2181 3154 2394 ntLink_8:21715383-21730455 O54697 5.55e-33 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Rattus norvegicus (Rat) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 20495 FUN_004304 3463 3045 2181 3154 2394 ntLink_8:21715383-21730455 O54697 6.86e-30 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Rattus norvegicus (Rat) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 20496 FUN_004304 3463 3045 2181 3154 2394 ntLink_8:21715383-21730455 O54697 1.34e-23 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Rattus norvegicus (Rat) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 20497 FUN_004304 3463 3045 2181 3154 2394 ntLink_8:21715383-21730455 O54697 7.21e-23 Aminopeptidase NAALADL1 (EC 3.4.11.-) (100 kDa ileum brush border membrane protein) (I100) (Ileal dipeptidylpeptidase) (N-acetylated-alpha-linked acidic dipeptidase-like protein) (NAALADase L) Rattus norvegicus (Rat) peptide catabolic process [GO:0043171]; proteolysis [GO:0006508] GO:0004177; GO:0004180; GO:0005509; GO:0006508; GO:0008237; GO:0008270; GO:0016020; GO:0016324; GO:0042803; GO:0043171 20498 FUN_004626 73737 68313 38801 50226 20239 NA NA NA NA NA NA NA 20499 FUN_031625 1 12 8 0 1 NA NA NA NA NA NA NA 20500 FUN_018133 0 236 0 0 0 NA NA NA NA NA NA NA 20501 FUN_018135 45 21 18 142 14 NA NA NA NA NA NA NA 20502 FUN_018137 2014 4714 2052 2259 856 NA NA NA NA NA NA NA 20503 FUN_018136 6425 9 1450 19 946 NA NA NA NA NA NA NA 20504 FUN_018139 1455 1440 675 1226 1361 NA NA NA NA NA NA NA 20505 FUN_018138 596 485 599 785 658 NA NA NA NA NA NA NA 20506 FUN_031627 3044 3469 2551 6672 1596 NA NA NA NA NA NA NA 20507 FUN_031628 1035 619 449 1026 1524 NA NA NA NA NA NA NA 20508 FUN_001501 1367 435 528 1558 947 NA NA NA NA NA NA NA 20509 FUN_017886 11 5 0 24 0 NA NA NA NA NA NA NA 20510 FUN_024838 0 0 0 0 34 NA NA NA NA NA NA NA 20511 FUN_024836 0 19 0 5 0 NA NA NA NA NA NA NA 20512 FUN_005951 49 41 22 25 54 NA NA NA NA NA NA NA 20513 FUN_005952 25 7 0 0 8 NA NA NA NA NA NA NA 20514 FUN_005954 13 0 0 0 22 NA NA NA NA NA NA NA 20515 FUN_034968 3162 2453 1662 3137 3192 ptg000025l:2219352-2221697 Q7ZXB8 2.04e-29 Polyadenylate-binding protein 2-B (PABP-2-B) (Poly(A)-binding protein 2-B) (Nuclear poly(A)-binding protein 1-B) (Poly(A)-binding protein II-B) (PABII-B) (Polyadenylate-binding nuclear protein 1-B) (XLnPABP2-B) (nPABP2-B) (xPABPII-B) Xenopus laevis (African clawed frog) cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; mRNA polyadenylation [GO:0006378]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247] GO:0000165; GO:0003723; GO:0005634; GO:0005737; GO:0006378; GO:0008143; GO:0042405; GO:0070063; GO:0071222; GO:1904247; GO:1990904 20516 FUN_034968 3162 2453 1662 3137 3192 ptg000025l:2219352-2221697 Q7ZXB8 2.04e-29 Polyadenylate-binding protein 2-B (PABP-2-B) (Poly(A)-binding protein 2-B) (Nuclear poly(A)-binding protein 1-B) (Poly(A)-binding protein II-B) (PABII-B) (Polyadenylate-binding nuclear protein 1-B) (XLnPABP2-B) (nPABP2-B) (xPABPII-B) Xenopus laevis (African clawed frog) cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; mRNA polyadenylation [GO:0006378]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247] GO:0000165; GO:0003723; GO:0005634; GO:0005737; GO:0006378; GO:0008143; GO:0042405; GO:0070063; GO:0071222; GO:1904247; GO:1990904 20517 FUN_034968 3162 2453 1662 3137 3192 ptg000025l:2219352-2221697 Q7ZXB8 2.04e-29 Polyadenylate-binding protein 2-B (PABP-2-B) (Poly(A)-binding protein 2-B) (Nuclear poly(A)-binding protein 1-B) (Poly(A)-binding protein II-B) (PABII-B) (Polyadenylate-binding nuclear protein 1-B) (XLnPABP2-B) (nPABP2-B) (xPABPII-B) Xenopus laevis (African clawed frog) cellular response to lipopolysaccharide [GO:0071222]; MAPK cascade [GO:0000165]; mRNA polyadenylation [GO:0006378]; positive regulation of polynucleotide adenylyltransferase activity [GO:1904247] GO:0000165; GO:0003723; GO:0005634; GO:0005737; GO:0006378; GO:0008143; GO:0042405; GO:0070063; GO:0071222; GO:1904247; GO:1990904 20518 FUN_034969 1727 1594 955 1161 826 NA NA NA NA NA NA NA 20519 FUN_035018 159 93 50 60 107 NA NA NA NA NA NA NA 20520 FUN_034960 845 484 603 992 1152 NA NA NA NA NA NA NA 20521 FUN_034961 646 539 431 476 402 NA NA NA NA NA NA NA 20522 FUN_034962 7021 8662 3969 7132 6528 NA NA NA NA NA NA NA 20523 FUN_034963 911 1262 519 2734 1687 NA NA NA NA NA NA NA 20524 FUN_034964 96 18 44 28 25 NA NA NA NA NA NA NA 20525 FUN_034965 1360 827 538 1008 1000 ptg000025l:2189615-2196599 O75521 8.12e-29 Enoyl-CoA delta isomerase 2 (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; fatty acid catabolic process [GO:0009062]; fatty acid metabolic process [GO:0006631] GO:0000062; GO:0004165; GO:0005739; GO:0005777; GO:0005782; GO:0005829; GO:0006631; GO:0006635; GO:0009062; GO:0016020; GO:0043231 20526 FUN_034966 624 565 374 409 434 ptg000025l:2196876-2198342 Q9D0S4 1.27e-29 Neuralized-like protein 2 Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; myofibril assembly [GO:0030239]; sarcomere organization [GO:0045214] GO:0005927; GO:0030239; GO:0030891; GO:0035556; GO:0045214; GO:0061630 20527 FUN_034967 4073 1170 875 3674 3382 NA NA NA NA NA NA NA 20528 FUN_032886 0 12 53 0 67 NA NA NA NA NA NA NA 20529 FUN_028129 366 201 247 203 117 NA NA NA NA NA NA NA 20530 FUN_028125 0 0 6 0 0 NA NA NA NA NA NA NA 20531 FUN_028124 0 0 8 0 0 NA NA NA NA NA NA NA 20532 FUN_006212 474 232 289 403 395 NA NA NA NA NA NA NA 20533 FUN_006211 216 216 153 653 549 ptg000001l:9281265-9288434 Q7RTR2 1.16e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20534 FUN_006211 216 216 153 653 549 ptg000001l:9281265-9288434 Q7RTR2 4.56e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20535 FUN_006211 216 216 153 653 549 ptg000001l:9281265-9288434 Q7RTR2 2.08e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20536 FUN_006211 216 216 153 653 549 ptg000001l:9281265-9288434 Q7RTR2 4.58e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20537 FUN_006211 216 216 153 653 549 ptg000001l:9281265-9288434 Q7RTR2 6e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20538 FUN_006211 216 216 153 653 549 ptg000001l:9281265-9288434 Q7RTR2 2.4e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20539 FUN_006210 55 119 38 14 0 NA NA NA NA NA NA NA 20540 FUN_006217 580 1140 695 1921 2341 NA NA NA NA NA NA NA 20541 FUN_006216 11 899 18 54 301 NA NA NA NA NA NA NA 20542 FUN_006215 1024 315 552 856 849 ptg000001l:9317712-9324641 Q7RTR2 7.79e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20543 FUN_006215 1024 315 552 856 849 ptg000001l:9317712-9324641 Q7RTR2 1.29e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20544 FUN_006214 226 289 294 719 700 NA NA NA NA NA NA NA 20545 FUN_042015 893 704 706 1157 855 NA NA NA NA NA NA NA 20546 FUN_042014 3299 1976 1807 2604 2890 ptg000035l:9813659-9818126 P33727 1.14e-23 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Felis catus (Cat) (Felis silvestris catus) colon epithelial cell migration [GO:0061580]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632] GO:0003943; GO:0005764; GO:0009986; GO:0010632; GO:0010976; GO:0046872; GO:0061580 20547 FUN_006219 468 370 358 676 368 NA NA NA NA NA NA NA 20548 FUN_006218 1989 1899 1302 2759 2093 NA NA NA NA NA NA NA 20549 FUN_042011 2688 2129 1195 2415 1607 ptg000035l:9794881-9798749 Q3ZBG9 2.74e-23 Phospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2) Bos taurus (Bovine) plasma membrane phospholipid scrambling [GO:0017121] GO:0005886; GO:0017121; GO:0017128; GO:0046872 20550 FUN_042010 1622 1081 624 977 619 NA NA NA NA NA NA NA 20551 FUN_042013 680 364 231 680 563 ptg000035l:9807561-9811385 P50429 3.59e-25 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 20552 FUN_042013 680 364 231 680 563 ptg000035l:9807561-9811385 P50429 3.59e-25 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 20553 FUN_042013 680 364 231 680 563 ptg000035l:9807561-9811385 P50429 5.96e-22 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 20554 FUN_042012 2744 3018 2230 2564 862 NA NA NA NA NA NA NA 20555 FUN_040525 69 180 46 26 65 NA NA NA NA NA NA NA 20556 FUN_040524 0 4 0 0 10 NA NA NA NA NA NA NA 20557 FUN_040523 29 34 0 20 25 NA NA NA NA NA NA NA 20558 FUN_040522 170 8 0 0 0 ptg000031l:9760480-9765176 Q5DU56 6.39e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20559 FUN_040522 170 8 0 0 0 ptg000031l:9760480-9765176 Q5DU56 5.33e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20560 FUN_040522 170 8 0 0 0 ptg000031l:9760480-9765176 Q5DU56 3.4e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20561 FUN_040522 170 8 0 0 0 ptg000031l:9760480-9765176 Q5DU56 8.56e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20562 FUN_040521 27 0 0 0 0 NA NA NA NA NA NA NA 20563 FUN_040520 39 68 4 0 91 NA NA NA NA NA NA NA 20564 FUN_040529 26 3 4 0 9 ptg000031l:9850875-9875990 Q7RTR2 5.27e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20565 FUN_040529 26 3 4 0 9 ptg000031l:9850875-9875990 Q7RTR2 9.31e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 20566 FUN_035619 82 53 57 219 99 NA NA NA NA NA NA NA 20567 FUN_035618 1970 1663 1085 2226 2252 NA NA NA NA NA NA NA 20568 FUN_035611 102 0 45 0 0 NA NA NA NA NA NA NA 20569 FUN_035610 1818 2141 1262 1866 924 NA NA NA NA NA NA NA 20570 FUN_035613 1348 414 727 1377 1364 ptg000025l:9882221-9883379 P53454 2.27e-45 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 20571 FUN_035612 595 304 265 589 658 NA NA NA NA NA NA NA 20572 FUN_035615 548 77 148 716 359 ptg000025l:9930168-9931955 Q9N2B7 1.75e-39 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) Gorilla gorilla gorilla (Western lowland gorilla) adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; behavior [GO:0007610]; bone remodeling [GO:0046849]; cellular response to alkaloid [GO:0071312]; cellular response to xenobiotic stimulus [GO:0071466]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; negative regulation of serotonin secretion [GO:0014063]; regulation of behavior [GO:0050795]; vasoconstriction [GO:0042310] GO:0004993; GO:0005886; GO:0007187; GO:0007198; GO:0007268; GO:0007610; GO:0014063; GO:0030425; GO:0030594; GO:0042310; GO:0045202; GO:0046849; GO:0050795; GO:0051378; GO:0071312; GO:0071466 20573 FUN_035614 14 0 15 2 0 NA NA NA NA NA NA NA 20574 FUN_030060 149 465 154 567 192 ptg000023l:8895520-8898879 Q4UMH6 2.98e-39 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 20575 FUN_030060 149 465 154 567 192 ptg000023l:8895520-8898879 Q4UMH6 2.1e-30 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 20576 FUN_030060 149 465 154 567 192 ptg000023l:8895520-8898879 Q4UMH6 5.1e-28 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 20577 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20578 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20579 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 0 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20580 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.89e-174 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20581 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 3.84e-163 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20582 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.29e-148 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20583 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 9.93e-133 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20584 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 2.8e-114 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20585 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 4.73e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20586 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 5.08e-38 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20587 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 9.48e-38 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20588 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.22e-37 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20589 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.33e-37 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20590 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 3.01e-37 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20591 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 5.15e-37 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20592 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.17e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20593 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.41e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20594 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.55e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20595 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.58e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20596 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.72e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20597 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.1e-35 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20598 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.18e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20599 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 7.62e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20600 FUN_032069 628 305 145 340 199 ptg000023l:28593988-28600957 P10079 1.96e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 20601 FUN_032063 3369 1843 253 1033 1548 NA NA NA NA NA NA NA 20602 FUN_032062 546 245 189 474 534 NA NA NA NA NA NA NA 20603 FUN_032061 18 158 243 195 214 ptg000023l:28552299-28556806 Q13077 6.26e-28 TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6) Homo sapiens (Human) apoptotic process [GO:0006915]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005737; GO:0005829; GO:0006915; GO:0008270; GO:0009898; GO:0031625; GO:0031996; GO:0033209; GO:0042802; GO:0043122; GO:0046330; GO:0051092; GO:0065003; GO:0070534; GO:2001236 20604 FUN_032067 2533 2026 1529 2968 1985 NA NA NA NA NA NA NA 20605 FUN_032066 29 18 14 35 46 ptg000023l:28587129-28587867 Q5HZQ9 3.7e-49 Pecanex-like protein 4 (Pecanex homolog protein 4) Xenopus laevis (African clawed frog) NA GO:0016020 20606 FUN_032065 1045 651 575 943 1041 ptg000023l:28580447-28587028 Q3UVY5 5.12e-73 Pecanex-like protein 4 (Pecanex homolog protein 4) Mus musculus (Mouse) NA GO:0016020 20607 FUN_032065 1045 651 575 943 1041 ptg000023l:28580447-28587028 Q3UVY5 1.46e-27 Pecanex-like protein 4 (Pecanex homolog protein 4) Mus musculus (Mouse) NA GO:0016020 20608 FUN_032064 1074 861 328 840 711 NA NA NA NA NA NA NA 20609 FUN_030065 124 10 34 77 39 NA NA NA NA NA NA NA 20610 FUN_043874 0 0 0 0 15 NA NA NA NA NA NA NA 20611 FUN_043876 42 114 101 118 266 NA NA NA NA NA NA NA 20612 FUN_043877 2 2 4 1 29 NA NA NA NA NA NA NA 20613 FUN_032398 0 183 144 150 214 NA NA NA NA NA NA NA 20614 FUN_043872 0 0 7 0 0 ptg000051l:342859-346887 P35067 2.01e-71 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 20615 FUN_032395 793 730 424 1914 767 ptg000023l:31463663-31465793 Q9H0Z9 7.83e-22 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 20616 FUN_032395 793 730 424 1914 767 ptg000023l:31463663-31465793 Q9H0Z9 7.83e-22 RNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [GO:0006977]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of cell population proliferation [GO:0008285]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of cell cycle [GO:0051726]; regulation of myotube differentiation [GO:0010830]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0003730; GO:0005634; GO:0005829; GO:0006397; GO:0006977; GO:0006978; GO:0007049; GO:0008285; GO:0008380; GO:0010830; GO:0030154; GO:0043484; GO:0048255; GO:0051726; GO:0070935 20617 FUN_032394 43207 21695 15201 21421 13536 NA NA NA NA NA NA NA 20618 FUN_032397 0 24 15 69 0 NA NA NA NA NA NA NA 20619 FUN_032396 8 58 8 40 0 ptg000023l:31474761-31534750 Q6V0K7 1.3e-22 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 20620 FUN_032391 747 677 373 479 439 NA NA NA NA NA NA NA 20621 FUN_043879 6 5 15 2 145 NA NA NA NA NA NA NA 20622 FUN_032393 2937 1935 1913 2552 1699 ptg000023l:31438440-31446572 B8JI71 7.91e-35 Protein eyes shut homolog Danio rerio (Zebrafish) (Brachydanio rerio) actin filament organization [GO:0007015]; photoreceptor cell maintenance [GO:0045494]; photoreceptor cell outer segment organization [GO:0035845]; response to stimulus [GO:0050896]; retinal cone cell development [GO:0046549]; visual perception [GO:0007601] GO:0005112; GO:0005509; GO:0005576; GO:0005737; GO:0005856; GO:0005929; GO:0007015; GO:0007601; GO:0033165; GO:0035845; GO:0045494; GO:0046549; GO:0050896 20623 FUN_032392 540 4077 1559 1948 715 NA NA NA NA NA NA NA 20624 FUN_003573 0 0 4 7 27 NA NA NA NA NA NA NA 20625 FUN_007621 0 0 0 23 0 NA NA NA NA NA NA NA 20626 FUN_007620 0 4 0 6 11 NA NA NA NA NA NA NA 20627 FUN_007622 0 7 0 13 20 NA NA NA NA NA NA NA 20628 FUN_007624 14 5 7 2 22 NA NA NA NA NA NA NA 20629 FUN_007626 2 6 12 4 17 NA NA NA NA NA NA NA 20630 FUN_008512 707 384 309 319 346 ptg000002l:12386800-12389224 Q55BN8 1.74e-38 Probable serine/threonine-protein kinase nek2 (EC 2.7.11.1) (Never in mitosis protein A-related protein kinase 2) (NimA-related protein kinase 2) Dictyostelium discoideum (Social amoeba) centrosome cycle [GO:0007098]; chromosome segregation [GO:0007059]; microtubule organizing center organization [GO:0031023]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0007059; GO:0007098; GO:0031023; GO:0045335; GO:0106310 20631 FUN_008512 707 384 309 319 346 ptg000002l:12386800-12389224 Q55BN8 1.74e-38 Probable serine/threonine-protein kinase nek2 (EC 2.7.11.1) (Never in mitosis protein A-related protein kinase 2) (NimA-related protein kinase 2) Dictyostelium discoideum (Social amoeba) centrosome cycle [GO:0007098]; chromosome segregation [GO:0007059]; microtubule organizing center organization [GO:0031023]; protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0006468; GO:0007059; GO:0007098; GO:0031023; GO:0045335; GO:0106310 20632 FUN_008513 247 247 118 321 422 ptg000002l:12392076-12393270 P48180 8.39e-44 Acetylcholine receptor subunit alpha-type acr-16 Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0042995; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1904315 20633 FUN_008510 17 13 22 0 0 NA NA NA NA NA NA NA 20634 FUN_008511 36 29 42 0 35 NA NA NA NA NA NA NA 20635 FUN_008516 14693 21543 6760 18223 15685 NA NA NA NA NA NA NA 20636 FUN_032388 222 113 129 202 221 NA NA NA NA NA NA NA 20637 FUN_008514 1559 953 748 1872 1809 ptg000002l:12396596-12400496 Q58A42 4.44e-22 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 20638 FUN_008514 1559 953 748 1872 1809 ptg000002l:12396596-12400496 Q58A42 4.44e-22 Protein DD3-3 Dictyostelium discoideum (Social amoeba) NA GO:0016020 20639 FUN_008515 9687 9293 4981 8133 5842 NA NA NA NA NA NA NA 20640 FUN_008518 356 368 195 238 242 ptg000002l:12436097-12437381 Q08B12 1.13e-80 Cytoplasmic tRNA 2-thiolation protein 2-A Xenopus laevis (African clawed frog) protein urmylation [GO:0032447]; tRNA thio-modification [GO:0034227]; tRNA wobble uridine modification [GO:0002098] GO:0000049; GO:0002098; GO:0005829; GO:0016779; GO:0032447; GO:0034227 20641 FUN_008519 3589 2569 2783 2905 1505 ptg000002l:12437540-12439075 A7S1L6 4.46e-103 GDP-fucose transporter 1 (Solute carrier family 35 member C1 homolog) Nematostella vectensis (Starlet sea anemone) carbohydrate transport [GO:0008643]; GDP-fucose import into Golgi lumen [GO:0036085]; protein O-linked fucosylation [GO:0036066] GO:0000139; GO:0005457; GO:0005794; GO:0008643; GO:0015297; GO:0036066; GO:0036085 20642 FUN_005173 1572 1398 891 2193 1309 ntLink_8:32103050-32108462 Q8VHR5 5.89e-33 Transcriptional repressor p66-beta (GATA zinc finger domain-containing protein 2B) (p66/p68) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of stem cell differentiation [GO:2000736] GO:0000122; GO:0000781; GO:0005634; GO:0005654; GO:0006338; GO:0008270; GO:0016575; GO:0016581; GO:0016607; GO:0042659; GO:0043565; GO:0045892; GO:0045893; GO:2000736 20643 FUN_005172 2305 4422 1598 1451 1428 NA NA NA NA NA NA NA 20644 FUN_005171 1174 1204 886 547 641 NA NA NA NA NA NA NA 20645 FUN_005170 68 0 23 35 75 NA NA NA NA NA NA NA 20646 FUN_041739 105 87 23 77 55 NA NA NA NA NA NA NA 20647 FUN_005176 28 16 3 0 14 ntLink_8:32193538-32198555 P23359 2.53e-21 Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) Mus musculus (Mouse) allantois development [GO:1905069]; ameloblast differentiation [GO:0036305]; anatomical structure formation involved in morphogenesis [GO:0048646]; animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; BMP signaling pathway [GO:0030509]; branching involved in salivary gland morphogenesis [GO:0060445]; branching morphogenesis of an epithelial tube [GO:0048754]; camera-type eye morphogenesis [GO:0048593]; cardiac muscle tissue development [GO:0048738]; cardiac septum morphogenesis [GO:0060411]; cartilage development [GO:0051216]; cell development [GO:0048468]; cell population proliferation [GO:0008283]; cellular response to BMP stimulus [GO:0071773]; chorio-allantoic fusion [GO:0060710]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic limb morphogenesis [GO:0030326]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint morphogenesis [GO:0060272]; endocardial cushion formation [GO:0003272]; epithelial cell differentiation [GO:0030855]; eye development [GO:0001654]; heart trabecula morphogenesis [GO:0061384]; hindbrain development [GO:0030902]; kidney development [GO:0001822]; mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:1901145]; mesenchymal cell differentiation [GO:0048762]; mesenchyme development [GO:0060485]; mesoderm formation [GO:0001707]; metanephric mesenchymal cell proliferation involved in metanephros development [GO:0072136]; metanephric mesenchyme morphogenesis [GO:0072133]; monocyte aggregation [GO:0070487]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell death [GO:0060548]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glomerular mesangial cell proliferation [GO:0072125]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis [GO:0072040]; negative regulation of mitotic nuclear division [GO:0045839]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of phosphorylation [GO:0042326]; negative regulation of prostatic bud formation [GO:0060686]; nephrogenic mesenchyme morphogenesis [GO:0072134]; neural fold elevation formation [GO:0021502]; neuron projection morphogenesis [GO:0048812]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; pattern specification process [GO:0007389]; pericardium morphogenesis [GO:0003344]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic process [GO:0043065]; positive regulation of bone mineralization [GO:0030501]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis [GO:1905312]; positive regulation of cell death [GO:0010942]; positive regulation of dendrite development [GO:1900006]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of hyaluranon cable assembly [GO:1900106]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to nucleus [GO:0034504]; regulation of branching involved in prostate gland morphogenesis [GO:0060687]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of phosphorylation [GO:0042325]; response to estradiol [GO:0032355]; response to peptide hormone [GO:0043434]; response to vitamin D [GO:0033280]; salivary gland morphogenesis [GO:0007435]; SMAD protein signal transduction [GO:0060395]; steroid hormone mediated signaling pathway [GO:0043401]; tube morphogenesis [GO:0035239]; ureteric bud development [GO:0001657] GO:0001503; GO:0001654; GO:0001657; GO:0001707; GO:0001822; GO:0003272; GO:0003344; GO:0005125; GO:0005615; GO:0007389; GO:0007411; GO:0007435; GO:0008083; GO:0008201; GO:0008283; GO:0008285; GO:0009880; GO:0009887; GO:0010628; GO:0010718; GO:0010800; GO:0010862; GO:0010942; GO:0021502; GO:0030326; GO:0030501; GO:0030509; GO:0030855; GO:0030858; GO:0030902; GO:0031982; GO:0032355; GO:0033280; GO:0034116; GO:0034504; GO:0035239; GO:0036305; GO:0042325; GO:0042326; GO:0042475; GO:0043065; GO:0043401; GO:0043407; GO:0043434; GO:0045665; GO:0045666; GO:0045669; GO:0045746; GO:0045786; GO:0045839; GO:0045892; GO:0045893; GO:0045944; GO:0048468; GO:0048593; GO:0048596; GO:0048646; GO:0048738; GO:0048754; GO:0048762; GO:0048812; GO:0050768; GO:0051216; GO:0060037; GO:0060272; GO:0060391; GO:0060393; GO:0060395; GO:0060411; GO:0060445; GO:0060485; GO:0060548; GO:0060686; GO:0060687; GO:0060710; GO:0061384; GO:0062023; GO:0070487; GO:0070700; GO:0071773; GO:0072040; GO:0072125; GO:0072133; GO:0072134; GO:0072136; GO:0090336; GO:1900006; GO:1900106; GO:1901145; GO:1905069; GO:1905312 20648 FUN_005175 2863 626 1764 4208 1996 ntLink_8:32135770-32178256 Q80YA8 1.47e-24 Protein crumbs homolog 2 (crumbs2) (Crumbs-like protein 2) Mus musculus (Mouse) circulatory system development [GO:0072359]; establishment of cell polarity [GO:0030010]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; ingression involved in gastrulation with mouth forming second [GO:0055111]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; mesoderm formation [GO:0001707]; negative regulation of endopeptidase activity [GO:0010951]; notochord formation [GO:0014028]; photoreceptor cell maintenance [GO:0045494]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; regulation of gastrulation [GO:0010470]; retina homeostasis [GO:0001895]; retinal cone cell development [GO:0046549]; somitogenesis [GO:0001756] GO:0001707; GO:0001756; GO:0001895; GO:0005509; GO:0005737; GO:0005886; GO:0007157; GO:0010470; GO:0010718; GO:0010951; GO:0014028; GO:0016324; GO:0016327; GO:0019828; GO:0030010; GO:0030054; GO:0030513; GO:0032991; GO:0035003; GO:0044877; GO:0045177; GO:0045197; GO:0045199; GO:0045494; GO:0046549; GO:0055111; GO:0072359 20649 FUN_032387 355 177 78 597 186 NA NA NA NA NA NA NA 20650 FUN_041734 3712 1695 1582 3600 3105 ptg000035l:6886491-6915224 Q9QYP0 3e-23 Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4) Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; BMP signaling pathway [GO:0030509]; cell migration involved in gastrulation [GO:0042074]; coronary vasculature development [GO:0060976]; craniofacial suture morphogenesis [GO:0097094]; determination of digestive tract left/right asymmetry [GO:0071907]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; embryonic heart tube left/right pattern formation [GO:0060971]; embryonic heart tube morphogenesis [GO:0003143]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; epiboly involved in gastrulation with mouth forming second [GO:0055113]; fasciculation of sensory neuron axon [GO:0097155]; left/right pattern formation [GO:0060972]; limb morphogenesis [GO:0035108]; negative regulation of smoothened signaling pathway [GO:0045879]; positive regulation of axon extension involved in axon guidance [GO:0048842]; regulation of gene expression [GO:0010468]; tissue development [GO:0009888] GO:0003143; GO:0005509; GO:0005634; GO:0007368; GO:0009887; GO:0009888; GO:0010468; GO:0016020; GO:0030326; GO:0030509; GO:0035108; GO:0042074; GO:0045879; GO:0048704; GO:0048842; GO:0055113; GO:0060971; GO:0060972; GO:0060976; GO:0061371; GO:0071907; GO:0097094; GO:0097155 20651 FUN_005179 0 0 0 2 46 NA NA NA NA NA NA NA 20652 FUN_005178 667 305 375 382 329 ntLink_8:32229688-32231722 Q5ZM55 2.25e-70 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Gallus gallus (Chicken) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 20653 FUN_041731 688 404 356 504 598 NA NA NA NA NA NA NA 20654 FUN_041730 2231 1956 1530 2645 2257 ptg000035l:6841546-6846950 P23092 4.25e-60 Transforming protein cbl Cas-NS-1 murine leukemia virus cell surface receptor signaling pathway [GO:0007166]; regulation of signaling [GO:0023051] GO:0001784; GO:0004842; GO:0005509; GO:0007166; GO:0023051 20655 FUN_041730 2231 1956 1530 2645 2257 ptg000035l:6841546-6846950 P23092 1.13e-41 Transforming protein cbl Cas-NS-1 murine leukemia virus cell surface receptor signaling pathway [GO:0007166]; regulation of signaling [GO:0023051] GO:0001784; GO:0004842; GO:0005509; GO:0007166; GO:0023051 20656 FUN_041733 0 0 0 11 55 NA NA NA NA NA NA NA 20657 FUN_041732 2188 1265 1071 1928 2896 ptg000035l:6865811-6883719 P20659 6.05e-21 Histone-lysine N-methyltransferase trithorax (EC 2.1.1.355) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Lysine N-methyltransferase 2A) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; eye development [GO:0001654]; germ cell migration [GO:0008354]; haltere development [GO:0007482]; heart development [GO:0007507]; histone H3-K4 methylation [GO:0051568]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968] GO:0000123; GO:0001654; GO:0003682; GO:0003700; GO:0005634; GO:0005700; GO:0005704; GO:0006325; GO:0007482; GO:0007507; GO:0008023; GO:0008157; GO:0008270; GO:0008354; GO:0032968; GO:0035097; GO:0042800; GO:0042802; GO:0042803; GO:0043565; GO:0044665; GO:0045893; GO:0045944; GO:0051568; GO:0106363; GO:0140949 20658 FUN_041951 1952 948 867 1525 1822 NA NA NA NA NA NA NA 20659 FUN_014281 7 0 8 2 1 NA NA NA NA NA NA NA 20660 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 9.59e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20661 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 2.81e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20662 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 4.5e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20663 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 6.26e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20664 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 3.89e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20665 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 4.23e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20666 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 1.53e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20667 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 1.41e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20668 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 2.51e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20669 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 5.12e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20670 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 8.27e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20671 FUN_032939 66 29 13 72 29 ptg000023l:37892608-37896861 Q96AY4 6.34e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20672 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.68e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20673 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.68e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20674 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.12e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20675 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 2.43e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20676 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 3.07e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20677 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 3.07e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20678 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 7.02e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20679 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 3.54e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20680 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 2.43e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20681 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 9.9e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20682 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 3.84e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20683 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.54e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20684 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.17e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20685 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.04e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20686 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 2.15e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20687 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 2.61e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20688 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 2.14e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20689 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 1.51e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20690 FUN_032938 26 12 18 26 18 ptg000023l:37872376-37877064 Q96AY4 4.06e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20691 FUN_032931 0 0 37 16 29 NA NA NA NA NA NA NA 20692 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 2.47e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20693 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 8.5e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20694 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 1.28e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20695 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 1.58e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20696 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 2.09e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20697 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 9.22e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20698 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 2.13e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20699 FUN_032933 163 34 50 57 24 ptg000023l:37794573-37798594 Q96AY4 5.12e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20700 FUN_032932 9 0 2 3 14 NA NA NA NA NA NA NA 20701 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 2.78e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20702 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 1.93e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20703 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 4.4e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20704 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 1.15e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20705 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 6.46e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20706 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 5.56e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20707 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 6.29e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20708 FUN_032935 132 62 65 49 14 ptg000023l:37825798-37828279 Q96AY4 4.46e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20709 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20710 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20711 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20712 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 1.05e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20713 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 1.14e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20714 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 2.87e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20715 FUN_032937 320 206 70 315 106 ptg000023l:37848954-37852986 Q96AY4 3.41e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20716 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.4e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20717 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.4e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20718 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.29e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20719 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.29e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20720 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 7.06e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20721 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 7.06e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20722 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.11e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20723 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.11e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20724 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 8.74e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20725 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 8.74e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20726 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.54e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20727 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.54e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20728 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 2.66e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20729 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 4.06e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20730 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.02e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20731 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.02e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20732 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 4.84e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20733 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 2.74e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20734 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 2.74e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20735 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.71e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20736 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.71e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20737 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 2.53e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20738 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 7.69e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20739 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 7.69e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20740 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 4.24e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20741 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 4.24e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20742 FUN_032936 30 33 3 0 34 ptg000023l:37847969-37848786 Q96AY4 1.48e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20743 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.59e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20744 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.59e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20745 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.59e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20746 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 5.52e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20747 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 5.52e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20748 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 5.52e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20749 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 2.74e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20750 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 2.74e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20751 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 2.74e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20752 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 2.78e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20753 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 2.78e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20754 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 2.78e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20755 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.8e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20756 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.8e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20757 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.8e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20758 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.48e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20759 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.48e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20760 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.48e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20761 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.26e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20762 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.26e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20763 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 8.85e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20764 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 8.85e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20765 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.38e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20766 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.38e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20767 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.21e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20768 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 3.21e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20769 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 5.66e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20770 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 5.66e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20771 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 7.78e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20772 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 7.78e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20773 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 1.36e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20774 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 6.16e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20775 FUN_028696 0 0 0 0 33 ptg000022l:2815806-2824295 Q96AY4 5.25e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20776 FUN_028695 12 12 0 10 9 NA NA NA NA NA NA NA 20777 FUN_031949 5043 3216 3675 3439 3329 NA NA NA NA NA NA NA 20778 FUN_041271 54 12 12 24 28 NA NA NA NA NA NA NA 20779 FUN_041272 583 1396 1236 198 605 NA NA NA NA NA NA NA 20780 FUN_028690 450 67 52 81 67 NA NA NA NA NA NA NA 20781 FUN_042839 2421 1781 1040 1622 1483 NA NA NA NA NA NA NA 20782 FUN_042838 2616 2543 1604 2326 1319 NA NA NA NA NA NA NA 20783 FUN_016754 25 0 0 0 0 NA NA NA NA NA NA NA 20784 FUN_016753 0 22 6 50 35 ptg000011l:6988910-6990832 Q96AY4 2.11e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20785 FUN_016752 0 76 5 131 18 ptg000011l:6971667-6984683 Q96AY4 5.16e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20786 FUN_016752 0 76 5 131 18 ptg000011l:6971667-6984683 Q96AY4 1.75e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20787 FUN_016752 0 76 5 131 18 ptg000011l:6971667-6984683 Q96AY4 7.02e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20788 FUN_016752 0 76 5 131 18 ptg000011l:6971667-6984683 Q96AY4 1.58e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20789 FUN_016752 0 76 5 131 18 ptg000011l:6971667-6984683 Q96AY4 1.99e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20790 FUN_042831 2621 2065 853 1243 2972 NA NA NA NA NA NA NA 20791 FUN_040062 11784 9640 5760 8456 6603 NA NA NA NA NA NA NA 20792 FUN_040066 719 2866 1128 3336 519 NA NA NA NA NA NA NA 20793 FUN_040067 200 112 101 303 158 NA NA NA NA NA NA NA 20794 FUN_003630 27 0 0 0 0 NA NA NA NA NA NA NA 20795 FUN_041278 25 0 0 74 0 NA NA NA NA NA NA NA 20796 FUN_003638 0 0 6 18 0 NA NA NA NA NA NA NA 20797 FUN_012274 1289 1039 689 727 1188 NA NA NA NA NA NA NA 20798 FUN_012275 3619 1996 1703 2277 2039 NA NA NA NA NA NA NA 20799 FUN_012276 2389 1893 1190 2635 1513 NA NA NA NA NA NA NA 20800 FUN_012277 0 0 13 64 14 NA NA NA NA NA NA NA 20801 FUN_012270 0 0 9 0 0 NA NA NA NA NA NA NA 20802 FUN_012271 3814 6645 2853 5567 2708 NA NA NA NA NA NA NA 20803 FUN_012272 147 174 34 190 163 NA NA NA NA NA NA NA 20804 FUN_012273 790 689 362 1209 729 NA NA NA NA NA NA NA 20805 FUN_012278 1856 1453 819 1908 1063 ptg000008l:7222791-7237303 Q6ZN84 4.1e-24 Coiled-coil domain-containing protein 81 Homo sapiens (Human) NA GO:0005737; GO:0005813 20806 FUN_012279 1320 953 850 1293 1221 NA NA NA NA NA NA NA 20807 FUN_028304 94 216 86 229 132 NA NA NA NA NA NA NA 20808 FUN_028307 119 34 66 0 130 NA NA NA NA NA NA NA 20809 FUN_028306 213 87 254 145 273 NA NA NA NA NA NA NA 20810 FUN_010690 0 23 0 36 71 ptg000007l:1626286-1628490 E7FAM5 5.38e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20811 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 5.11e-90 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20812 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 1.29e-87 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20813 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 1.72e-87 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20814 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 5.94e-86 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20815 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 5.49e-82 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20816 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 2.45e-77 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20817 FUN_010691 185 201 26 40 229 ptg000007l:1648284-1713280 E7FAM5 2.63e-65 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20818 FUN_010692 76 292 94 5 264 ptg000007l:1719674-1721114 E7FAM5 1.14e-49 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20819 FUN_010693 85 16 109 27 57 ptg000007l:1724391-1730313 E7FAM5 1.48e-88 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20820 FUN_028309 3375 1769 1125 2026 2016 NA NA NA NA NA NA NA 20821 FUN_028308 0 24 61 0 12 NA NA NA NA NA NA NA 20822 FUN_002507 562 2 0 26 0 NA NA NA NA NA NA NA 20823 FUN_044276 625 1337 471 1293 849 ptg000132l:19246-22205 Q5TNH5 8.23e-45 Glucosamine-6-phosphate isomerase (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase) (GNPDA) (GlcN6P deaminase) Anopheles gambiae (African malaria mosquito) carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262] GO:0004342; GO:0005737; GO:0005975; GO:0006043; GO:0006046; GO:0006091; GO:0019262; GO:0042802 20824 FUN_044276 625 1337 471 1293 849 ptg000132l:19246-22205 Q5TNH5 1.07e-24 Glucosamine-6-phosphate isomerase (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase) (GNPDA) (GlcN6P deaminase) Anopheles gambiae (African malaria mosquito) carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262] GO:0004342; GO:0005737; GO:0005975; GO:0006043; GO:0006046; GO:0006091; GO:0019262; GO:0042802 20825 FUN_009503 70 35 18 40 70 NA NA NA NA NA NA NA 20826 FUN_002505 1097 388 270 808 389 NA NA NA NA NA NA NA 20827 FUN_002504 451 94 7 317 9 NA NA NA NA NA NA NA 20828 FUN_002502 131 77 37 29 50 NA NA NA NA NA NA NA 20829 FUN_013585 1758 1495 930 1730 1391 NA NA NA NA NA NA NA 20830 FUN_013584 988 358 227 274 90 NA NA NA NA NA NA NA 20831 FUN_013587 3050 5010 1823 3207 2240 NA NA NA NA NA NA NA 20832 FUN_013586 1137 674 464 405 243 NA NA NA NA NA NA NA 20833 FUN_013581 1733 1219 666 851 945 NA NA NA NA NA NA NA 20834 FUN_013580 1062 1217 241 812 405 NA NA NA NA NA NA NA 20835 FUN_013583 2562 2227 1181 1168 895 NA NA NA NA NA NA NA 20836 FUN_013582 1564 1298 539 915 855 NA NA NA NA NA NA NA 20837 FUN_013589 1429 853 332 1069 422 NA NA NA NA NA NA NA 20838 FUN_013588 440 543 305 436 386 ptg000008l:24295884-24296985 O75752 1.28e-27 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Homo sapiens (Human) glycosphingolipid metabolic process [GO:0006687]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006687; GO:0008194; GO:0008499; GO:0009312; GO:0016757; GO:0047273 20839 FUN_043005 776 336 463 827 421 ptg000047l:2894647-2901679 P49117 5.28e-24 Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4) Mus musculus (Mouse) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; cerebellum development [GO:0021549]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; meiotic cell cycle [GO:0051321]; negative regulation of transcription by RNA polymerase II [GO:0000122]; p38MAPK cascade [GO:0038066]; positive regulation of behavior [GO:0048520]; positive regulation of embryonic development [GO:0040019]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatogenesis [GO:0007283] GO:0000122; GO:0000977; GO:0000978; GO:0001228; GO:0003700; GO:0004879; GO:0005654; GO:0006357; GO:0007283; GO:0008270; GO:0021549; GO:0030154; GO:0031663; GO:0038066; GO:0040019; GO:0043565; GO:0045663; GO:0045944; GO:0048520; GO:0048856; GO:0051321; GO:1990837 20840 FUN_043004 2253 987 766 1744 1501 ptg000047l:2876816-2890981 Q64380 1.56e-54 Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) Rattus norvegicus (Rat) choline catabolic process [GO:0042426]; glycine biosynthetic process [GO:0006545]; sarcosine catabolic process [GO:1901053]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006545; GO:0008480; GO:0016491; GO:0035999; GO:0042426; GO:0050660; GO:1901053 20841 FUN_043004 2253 987 766 1744 1501 ptg000047l:2876816-2890981 Q64380 1.27e-45 Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) Rattus norvegicus (Rat) choline catabolic process [GO:0042426]; glycine biosynthetic process [GO:0006545]; sarcosine catabolic process [GO:1901053]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006545; GO:0008480; GO:0016491; GO:0035999; GO:0042426; GO:0050660; GO:1901053 20842 FUN_043004 2253 987 766 1744 1501 ptg000047l:2876816-2890981 Q64380 3.33e-45 Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) Rattus norvegicus (Rat) choline catabolic process [GO:0042426]; glycine biosynthetic process [GO:0006545]; sarcosine catabolic process [GO:1901053]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006545; GO:0008480; GO:0016491; GO:0035999; GO:0042426; GO:0050660; GO:1901053 20843 FUN_043004 2253 987 766 1744 1501 ptg000047l:2876816-2890981 Q64380 1.04e-30 Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) Rattus norvegicus (Rat) choline catabolic process [GO:0042426]; glycine biosynthetic process [GO:0006545]; sarcosine catabolic process [GO:1901053]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006545; GO:0008480; GO:0016491; GO:0035999; GO:0042426; GO:0050660; GO:1901053 20844 FUN_043004 2253 987 766 1744 1501 ptg000047l:2876816-2890981 Q64380 2.56e-22 Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) Rattus norvegicus (Rat) choline catabolic process [GO:0042426]; glycine biosynthetic process [GO:0006545]; sarcosine catabolic process [GO:1901053]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006545; GO:0008480; GO:0016491; GO:0035999; GO:0042426; GO:0050660; GO:1901053 20845 FUN_043007 3948 3346 2529 4858 2897 ptg000047l:2910134-2913965 A3BF39 2.73e-107 Cadmium/zinc-transporting ATPase HMA2 (EC 7.2.2.12) (EC 7.2.2.21) (Protein HEAVY METAL ATPASE 2) (OsHMA2) Oryza sativa subsp. japonica (Rice) NA GO:0005385; GO:0005524; GO:0005886; GO:0008551; GO:0015086; GO:0016463; GO:0016887; GO:0046872 20846 FUN_012188 141 119 92 415 208 NA NA NA NA NA NA NA 20847 FUN_012186 2002 3203 2194 1993 1738 ptg000008l:6210833-6216192 O08807 3.81e-21 Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4) Mus musculus (Mouse) cell redox homeostasis [GO:0045454]; extracellular matrix organization [GO:0030198]; male gonad development [GO:0008584]; negative regulation of male germ cell proliferation [GO:2000255]; peptidyl-proline hydroxylation to 4-hydroxy-L-proline [GO:0018401]; protein maturation by protein folding [GO:0022417]; reactive oxygen species metabolic process [GO:0072593]; response to oxidative stress [GO:0006979]; spermatogenesis [GO:0007283] GO:0005615; GO:0005737; GO:0005739; GO:0005783; GO:0005790; GO:0005829; GO:0006979; GO:0007283; GO:0008584; GO:0018401; GO:0022417; GO:0030198; GO:0042802; GO:0045454; GO:0060090; GO:0072593; GO:0140313; GO:0140824; GO:2000255 20848 FUN_012187 261 128 165 1486 520 NA NA NA NA NA NA NA 20849 FUN_012184 3018 2806 1762 2105 1823 ptg000008l:6162573-6197510 Q96DM1 2.15e-50 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 20850 FUN_012185 240 392 255 1051 764 NA NA NA NA NA NA NA 20851 FUN_012182 65 35 158 81 157 NA NA NA NA NA NA NA 20852 FUN_011568 14 0 12 0 18 NA NA NA NA NA NA NA 20853 FUN_012180 1764 796 684 1269 1453 NA NA NA NA NA NA NA 20854 FUN_012181 13 0 55 0 44 NA NA NA NA NA NA NA 20855 FUN_013639 146 127 61 223 154 ptg000008l:24836875-24844165 P31423 6.74e-47 Metabotropic glutamate receptor 4 (mGluR4) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gamma-aminobutyric acid secretion [GO:0014051]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuron projection development [GO:0031175]; positive regulation of MAPK cascade [GO:0043410]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004930; GO:0005516; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007612; GO:0008066; GO:0008285; GO:0014051; GO:0031175; GO:0031410; GO:0035249; GO:0043005; GO:0043066; GO:0043195; GO:0043198; GO:0043410; GO:0043523; GO:0048306; GO:0048787; GO:0050805; GO:0051932; GO:0051966; GO:0098688; GO:0098978; GO:0099171; GO:0150048; GO:2000300 20856 FUN_013638 67 10 24 18 56 NA NA NA NA NA NA NA 20857 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 7.68e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20858 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 2.67e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20859 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 3e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20860 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 1.89e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20861 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 1.38e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20862 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 8.01e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20863 FUN_013636 14 4 28 24 66 ptg000008l:24781251-24786899 Q96AY4 2.69e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20864 FUN_013635 6 17 207 159 425 ptg000008l:24760337-24770349 Q96AY4 5.06e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20865 FUN_013635 6 17 207 159 425 ptg000008l:24760337-24770349 Q96AY4 1.01e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20866 FUN_013635 6 17 207 159 425 ptg000008l:24760337-24770349 Q96AY4 5.42e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20867 FUN_013635 6 17 207 159 425 ptg000008l:24760337-24770349 Q96AY4 6.29e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20868 FUN_013635 6 17 207 159 425 ptg000008l:24760337-24770349 Q96AY4 8.36e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20869 FUN_013634 515 300 209 352 355 NA NA NA NA NA NA NA 20870 FUN_013633 947 2025 421 1089 420 NA NA NA NA NA NA NA 20871 FUN_013632 112 169 95 85 46 NA NA NA NA NA NA NA 20872 FUN_013631 360 254 147 383 370 NA NA NA NA NA NA NA 20873 FUN_013630 217 79 131 101 24 ptg000008l:24718873-24719779 Q6PBI8 1.14e-21 Transmembrane protein 177 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005743; GO:0016020 20874 FUN_041726 780 856 458 860 595 ptg000035l:6823426-6826956 Q9ES56 2.9e-31 Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; dendrite development [GO:0016358]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005737; GO:0005783; GO:0005795; GO:0005886; GO:0006888; GO:0006901; GO:0006914; GO:0008021; GO:0016192; GO:0016358; GO:0030008; GO:0030425; GO:0045202; GO:0045211; GO:0048208; GO:0099022; GO:1990071; GO:1990072 20875 FUN_041726 780 856 458 860 595 ptg000035l:6823426-6826956 Q9ES56 2.9e-31 Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog) Mus musculus (Mouse) autophagy [GO:0006914]; COPII vesicle coating [GO:0048208]; dendrite development [GO:0016358]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; vesicle coating [GO:0006901]; vesicle tethering [GO:0099022]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005737; GO:0005783; GO:0005795; GO:0005886; GO:0006888; GO:0006901; GO:0006914; GO:0008021; GO:0016192; GO:0016358; GO:0030008; GO:0030425; GO:0045202; GO:0045211; GO:0048208; GO:0099022; GO:1990071; GO:1990072 20876 FUN_005166 286 624 486 354 436 NA NA NA NA NA NA NA 20877 FUN_003949 0 0 37 17 12 NA NA NA NA NA NA NA 20878 FUN_009674 4026 3582 2203 3156 2236 ptg000004l:10232248-10236370 Q8CJ67 6.64e-51 Double-stranded RNA-binding protein Staufen homolog 2 Mus musculus (Mouse) anterograde dendritic transport of messenger ribonucleoprotein complex [GO:0098964]; cellular response to oxidative stress [GO:0034599]; eye morphogenesis [GO:0048592]; germ cell development [GO:0007281]; intracellular mRNA localization [GO:0008298]; positive regulation of dendritic spine morphogenesis [GO:0061003]; positive regulation of long-term synaptic depression [GO:1900454]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of filopodium assembly [GO:0051489]; regulation of gene expression [GO:0010468] GO:0003725; GO:0003729; GO:0005634; GO:0005730; GO:0005737; GO:0005783; GO:0005874; GO:0005886; GO:0007281; GO:0008298; GO:0010468; GO:0010494; GO:0019894; GO:0030424; GO:0030425; GO:0030544; GO:0031965; GO:0032839; GO:0032956; GO:0034599; GO:0035418; GO:0043005; GO:0043022; GO:0043025; GO:0043198; GO:0048592; GO:0051019; GO:0051489; GO:0051965; GO:0061003; GO:0098964; GO:1900454; GO:1990124 20879 FUN_009675 540 412 775 728 475 ptg000004l:10243907-10251941 Q99N01 1.32e-36 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Rattus norvegicus (Rat) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 20880 FUN_009676 32 94 87 28 28 NA NA NA NA NA NA NA 20881 FUN_009677 18262 23538 10155 15058 13946 NA NA NA NA NA NA NA 20882 FUN_009670 194 87 113 63 157 NA NA NA NA NA NA NA 20883 FUN_009671 498 290 282 279 202 NA NA NA NA NA NA NA 20884 FUN_009672 708 575 363 531 566 NA NA NA NA NA NA NA 20885 FUN_009673 787 351 364 777 444 NA NA NA NA NA NA NA 20886 FUN_005160 31042 32563 19247 41739 10478 NA NA NA NA NA NA NA 20887 FUN_041189 0 1332 201 731 256 NA NA NA NA NA NA NA 20888 FUN_009678 202 220 155 251 217 NA NA NA NA NA NA NA 20889 FUN_005161 724 508 366 360 501 NA NA NA NA NA NA NA 20890 FUN_029553 143 41 60 91 148 NA NA NA NA NA NA NA 20891 FUN_029552 85 9 33 12 242 NA NA NA NA NA NA NA 20892 FUN_029551 255 148 89 167 417 NA NA NA NA NA NA NA 20893 FUN_029550 1314 551 512 895 799 NA NA NA NA NA NA NA 20894 FUN_029557 655 399 362 578 1009 ptg000023l:3331828-3356385 Q8BFY9 1.38e-41 Transportin-1 (Importin beta-2) (Karyopherin beta-2) Mus musculus (Mouse) protein import into nucleus [GO:0006606] GO:0005634; GO:0005737; GO:0006606; GO:0008139; GO:0031267; GO:0061608 20895 FUN_029557 655 399 362 578 1009 ptg000023l:3331828-3356385 Q8BFY9 1.47e-32 Transportin-1 (Importin beta-2) (Karyopherin beta-2) Mus musculus (Mouse) protein import into nucleus [GO:0006606] GO:0005634; GO:0005737; GO:0006606; GO:0008139; GO:0031267; GO:0061608 20896 FUN_029556 40 41 26 35 18 NA NA NA NA NA NA NA 20897 FUN_029555 274 68 115 122 106 NA NA NA NA NA NA NA 20898 FUN_029559 1221 1557 674 178 1429 ptg000023l:3369451-3371626 E7FAM5 2.84e-54 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20899 FUN_005163 581 459 286 440 418 ntLink_8:31983980-31987189 Q562D6 1.94e-28 tRNA (adenine(37)-N6)-methyltransferase (EC 2.1.1.-) (tRNA methyltransferase O) Mus musculus (Mouse) tRNA methylation [GO:0030488] GO:0003723; GO:0030488; GO:0089715 20900 FUN_041184 906 809 29 448 211 NA NA NA NA NA NA NA 20901 FUN_030161 0 0 0 7 10 NA NA NA NA NA NA NA 20902 FUN_026266 0 13 45 35 153 NA NA NA NA NA NA NA 20903 FUN_003947 14 0 0 25 0 NA NA NA NA NA NA NA 20904 FUN_003940 83 0 78 35 0 NA NA NA NA NA NA NA 20905 FUN_041180 3 4 12 0 3 NA NA NA NA NA NA NA 20906 FUN_009586 24 13 4 131 31 ptg000004l:8964169-8965450 Q80XJ3 3.61e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 20907 FUN_009587 108 30 18 40 31 ptg000004l:8986990-8993744 Q96AY4 2.92e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20908 FUN_009587 108 30 18 40 31 ptg000004l:8986990-8993744 Q96AY4 8.59e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20909 FUN_009587 108 30 18 40 31 ptg000004l:8986990-8993744 Q96AY4 5.82e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20910 FUN_009587 108 30 18 40 31 ptg000004l:8986990-8993744 Q96AY4 4.47e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20911 FUN_009587 108 30 18 40 31 ptg000004l:8986990-8993744 Q96AY4 9.77e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20912 FUN_009584 25 0 7 2 40 NA NA NA NA NA NA NA 20913 FUN_009583 18 3 29 0 8 NA NA NA NA NA NA NA 20914 FUN_009580 498 254 141 533 255 NA NA NA NA NA NA NA 20915 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.02e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20916 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 8.17e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20917 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 3.41e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20918 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 6.88e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20919 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 4.09e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20920 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 3.31e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20921 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 2.55e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20922 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 2.96e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20923 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 2.49e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20924 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.44e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20925 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 3.07e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20926 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.41e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20927 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.64e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20928 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 6.86e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20929 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.01e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20930 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 8.4e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20931 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 3.06e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20932 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.85e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20933 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 8.14e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20934 FUN_009581 1042 42 27 1024 721 ptg000004l:8839875-8843399 Q96AY4 1.35e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 20935 FUN_044219 4 0 8 0 82 NA NA NA NA NA NA NA 20936 FUN_016038 4183 4543 2775 2916 1603 NA NA NA NA NA NA NA 20937 FUN_016039 9 0 13 37 17 NA NA NA NA NA NA NA 20938 FUN_016032 383 1993 705 497 338 NA NA NA NA NA NA NA 20939 FUN_016033 849 784 482 242 164 ptg000010l:897218-903135 P70579 1.43e-114 Metabotropic glutamate receptor 8 (mGluR8) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron death [GO:1901214]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001642; GO:0004930; GO:0005886; GO:0007193; GO:0007196; GO:0007216; GO:0007268; GO:0008066; GO:0019233; GO:0035249; GO:0042734; GO:0043005; GO:0043025; GO:0045211; GO:0046928; GO:0048787; GO:0050966; GO:0051966; GO:0098978; GO:0098982; GO:0099171; GO:1901214 20940 FUN_016033 849 784 482 242 164 ptg000010l:897218-903135 P70579 8.68e-47 Metabotropic glutamate receptor 8 (mGluR8) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron death [GO:1901214]; regulation of neurotransmitter secretion [GO:0046928]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001642; GO:0004930; GO:0005886; GO:0007193; GO:0007196; GO:0007216; GO:0007268; GO:0008066; GO:0019233; GO:0035249; GO:0042734; GO:0043005; GO:0043025; GO:0045211; GO:0046928; GO:0048787; GO:0050966; GO:0051966; GO:0098978; GO:0098982; GO:0099171; GO:1901214 20941 FUN_042350 905 475 600 395 1621 NA NA NA NA NA NA NA 20942 FUN_016034 210 69 96 181 55 ptg000010l:913836-916020 E7FAM5 8.83e-92 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 20943 FUN_031695 111 47 114 147 111 ptg000023l:24452794-24457714 A1L1W9 3.62e-23 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 20944 FUN_007973 1833 942 1169 2338 2316 ptg000002l:6685633-6726089 P97412 4.32e-25 Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog) Mus musculus (Mouse) blood coagulation [GO:0007596]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; granulocyte chemotaxis [GO:0071621]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; microtubule-based process [GO:0007017]; natural killer cell mediated cytotoxicity [GO:0042267]; neutrophil mediated immunity [GO:0002446]; phagocytosis [GO:0006909]; phospholipid homeostasis [GO:0055091]; phospholipid metabolic process [GO:0006644]; pigment granule organization [GO:0048753]; pigmentation [GO:0043473]; positive regulation of natural killer cell activation [GO:0032816]; protein localization [GO:0008104]; response to xenobiotic stimulus [GO:0009410]; secretion of lysosomal enzymes [GO:0033299]; T cell mediated immunity [GO:0002456] GO:0002446; GO:0002456; GO:0005829; GO:0006644; GO:0006909; GO:0007017; GO:0007040; GO:0007596; GO:0008104; GO:0009410; GO:0015630; GO:0016020; GO:0019901; GO:0032438; GO:0032510; GO:0032816; GO:0033299; GO:0033364; GO:0042267; GO:0042742; GO:0042832; GO:0043473; GO:0048753; GO:0051607; GO:0055091; GO:0071621 20945 FUN_007973 1833 942 1169 2338 2316 ptg000002l:6685633-6726089 P97412 4.32e-25 Lysosomal-trafficking regulator (Beige protein) (CHS1 homolog) Mus musculus (Mouse) blood coagulation [GO:0007596]; defense response to bacterium [GO:0042742]; defense response to protozoan [GO:0042832]; defense response to virus [GO:0051607]; endosome to lysosome transport via multivesicular body sorting pathway [GO:0032510]; granulocyte chemotaxis [GO:0071621]; lysosome organization [GO:0007040]; mast cell secretory granule organization [GO:0033364]; melanosome organization [GO:0032438]; microtubule-based process [GO:0007017]; natural killer cell mediated cytotoxicity [GO:0042267]; neutrophil mediated immunity [GO:0002446]; phagocytosis [GO:0006909]; phospholipid homeostasis [GO:0055091]; phospholipid metabolic process [GO:0006644]; pigment granule organization [GO:0048753]; pigmentation [GO:0043473]; positive regulation of natural killer cell activation [GO:0032816]; protein localization [GO:0008104]; response to xenobiotic stimulus [GO:0009410]; secretion of lysosomal enzymes [GO:0033299]; T cell mediated immunity [GO:0002456] GO:0002446; GO:0002456; GO:0005829; GO:0006644; GO:0006909; GO:0007017; GO:0007040; GO:0007596; GO:0008104; GO:0009410; GO:0015630; GO:0016020; GO:0019901; GO:0032438; GO:0032510; GO:0032816; GO:0033299; GO:0033364; GO:0042267; GO:0042742; GO:0042832; GO:0043473; GO:0048753; GO:0051607; GO:0055091; GO:0071621 20946 FUN_001973 0 0 21 2 17 NA NA NA NA NA NA NA 20947 FUN_031693 92 184 17 71 146 ptg000023l:24443116-24447787 Q8TF71 1.16e-23 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Homo sapiens (Human) amino acid transport [GO:0006865]; aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0006865; GO:0015171; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 20948 FUN_001970 6 0 0 19 0 NA NA NA NA NA NA NA 20949 FUN_008985 3322 2665 1710 3869 3397 NA NA NA NA NA NA NA 20950 FUN_008984 3372 1291 1800 2721 1993 NA NA NA NA NA NA NA 20951 FUN_008987 3028 3327 1701 3302 1477 ptg000004l:1147594-1156063 E1BKH1 6.43e-32 EF-hand domain-containing protein 1 (Myoclonin-1) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; cilium-dependent cell motility [GO:0060285]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; regulation of cell division [GO:0051302] GO:0000281; GO:0000922; GO:0005509; GO:0005813; GO:0005879; GO:0005930; GO:0007052; GO:0021795; GO:0043014; GO:0051302; GO:0060285; GO:0072686 20952 FUN_008987 3028 3327 1701 3302 1477 ptg000004l:1147594-1156063 E1BKH1 2.87e-28 EF-hand domain-containing protein 1 (Myoclonin-1) Bos taurus (Bovine) cerebral cortex cell migration [GO:0021795]; cilium-dependent cell motility [GO:0060285]; mitotic cytokinesis [GO:0000281]; mitotic spindle organization [GO:0007052]; regulation of cell division [GO:0051302] GO:0000281; GO:0000922; GO:0005509; GO:0005813; GO:0005879; GO:0005930; GO:0007052; GO:0021795; GO:0043014; GO:0051302; GO:0060285; GO:0072686 20953 FUN_008986 908 867 1194 508 361 NA NA NA NA NA NA NA 20954 FUN_008981 786 517 406 886 841 ptg000004l:1087274-1096339 Q9UK96 4.93e-39 F-box only protein 10 Homo sapiens (Human) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0006915; GO:0016567; GO:0042981 20955 FUN_008981 786 517 406 886 841 ptg000004l:1087274-1096339 Q9UK96 5.86e-38 F-box only protein 10 Homo sapiens (Human) apoptotic process [GO:0006915]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0004842; GO:0005737; GO:0005829; GO:0006511; GO:0006915; GO:0016567; GO:0042981 20956 FUN_008980 4343 3918 2502 4513 4135 NA NA NA NA NA NA NA 20957 FUN_008983 340 150 151 151 109 NA NA NA NA NA NA NA 20958 FUN_008982 8 0 0 3 8 NA NA NA NA NA NA NA 20959 FUN_008989 3824 6471 3702 4013 3506 ptg000004l:1164120-1167227 Q9VRV7 3.87e-23 Splicing factor 3B subunit 6 (Pre-mRNA branch site p14-like protein) Drosophila melanogaster (Fruit fly) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003729; GO:0005684; GO:0005686; GO:0005689; GO:0071011; GO:0071013 20960 FUN_008988 7785 14070 5297 8768 5053 NA NA NA NA NA NA NA 20961 FUN_009047 46 35 10 7 34 NA NA NA NA NA NA NA 20962 FUN_009046 54 22 0 34 34 NA NA NA NA NA NA NA 20963 FUN_002013 0 0 6 0 0 NA NA NA NA NA NA NA 20964 FUN_031698 1379 995 544 1028 483 NA NA NA NA NA NA NA 20965 FUN_025795 122 126 263 286 242 NA NA NA NA NA NA NA 20966 FUN_025794 21558 28161 16797 18598 15308 ptg000020l:746960-749997 P61359 7.75e-34 60S ribosomal protein L27 Hippocampus comes (Tiger tail seahorse) erythrocyte differentiation [GO:0030218]; translation [GO:0006412] GO:0003735; GO:0005829; GO:0006412; GO:0015934; GO:0030218; GO:0098556 20967 FUN_017639 0 0 0 0 238 NA NA NA NA NA NA NA 20968 FUN_025796 239 280 287 241 306 NA NA NA NA NA NA NA 20969 FUN_025791 15419 14997 10018 16262 10620 ptg000020l:735094-738437 P35213 4.52e-78 14-3-3 protein beta/alpha (Prepronerve growth factor RNH-1) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] Rattus norvegicus (Rat) cytoplasmic sequestering of protein [GO:0051220]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of protein dephosphorylation [GO:0035308]; positive regulation of catalytic activity [GO:0043085]; protein targeting [GO:0006605]; signal transduction [GO:0007165] GO:0004860; GO:0005634; GO:0005737; GO:0005829; GO:0006605; GO:0007165; GO:0008022; GO:0017053; GO:0019899; GO:0019904; GO:0032991; GO:0035308; GO:0042470; GO:0042802; GO:0042826; GO:0043085; GO:0044877; GO:0045744; GO:0045892; GO:0048471; GO:0050815; GO:0051219; GO:0051220 20970 FUN_025790 2042 1701 1164 1639 1238 NA NA NA NA NA NA NA 20971 FUN_025793 349 197 210 264 405 ptg000020l:741622-744321 Q9UNA4 4.34e-42 DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B) Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985] GO:0003684; GO:0003887; GO:0005654; GO:0006260; GO:0006281; GO:0016607; GO:0019985; GO:0036464; GO:0042276; GO:0046872 20972 FUN_025793 349 197 210 264 405 ptg000020l:741622-744321 Q9UNA4 2.99e-27 DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B) Homo sapiens (Human) DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; translesion synthesis [GO:0019985] GO:0003684; GO:0003887; GO:0005654; GO:0006260; GO:0006281; GO:0016607; GO:0019985; GO:0036464; GO:0042276; GO:0046872 20973 FUN_025792 7315 5943 4192 8208 6458 ptg000020l:738895-739621 Q52M98 2.26e-94 14-3-3 protein theta Xenopus laevis (African clawed frog) NA GO:0005737 20974 FUN_017633 0 163 15 0 69 NA NA NA NA NA NA NA 20975 FUN_017631 0 0 11 0 164 NA NA NA NA NA NA NA 20976 FUN_017630 0 0 0 0 121 NA NA NA NA NA NA NA 20977 FUN_025799 382 365 404 494 118 NA NA NA NA NA NA NA 20978 FUN_025798 139 144 213 181 282 ptg000020l:762408-764579 P0CB42 2.12e-26 Nucleic acid dioxygenase ALKBH1 (EC 1.14.11.-) (Alkylated DNA repair protein alkB homolog 1) (Alpha-ketoglutarate-dependent dioxygenase ABH1) (DNA 6mA demethylase) (DNA N6-methyl adenine demethylase ALKBH1) (EC 1.14.11.51) (DNA lyase ABH1) (EC 4.2.99.18) (DNA oxidative demethylase ALKBH1) (EC 1.14.11.33) (mRNA N(3)-methylcytidine demethylase) (EC 1.14.11.-) (tRNA N1-methyl adenine demethylase) (EC 1.14.11.-) Mus musculus (Mouse) cell differentiation [GO:0030154]; developmental growth [GO:0048589]; DNA dealkylation involved in DNA repair [GO:0006307]; DNA demethylation [GO:0080111]; DNA repair [GO:0006281]; in utero embryonic development [GO:0001701]; negative regulation of neuron apoptotic process [GO:0043524]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; oxidative demethylation [GO:0070989]; oxidative RNA demethylation [GO:0035513]; oxidative single-stranded DNA demethylation [GO:0035552]; placenta development [GO:0001890]; regulation of gene expression [GO:0010468]; regulation of mitochondrial translation [GO:0070129]; regulation of translational elongation [GO:0006448]; regulation of translational initiation [GO:0006446]; RNA repair [GO:0042245]; tRNA demethylation [GO:1990983]; tRNA wobble cytosine modification [GO:0002101] GO:0000049; GO:0000791; GO:0001701; GO:0001764; GO:0001890; GO:0002101; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005783; GO:0006281; GO:0006307; GO:0006446; GO:0006448; GO:0008198; GO:0010468; GO:0016706; GO:0030154; GO:0031175; GO:0035513; GO:0035515; GO:0035516; GO:0035552; GO:0042056; GO:0042245; GO:0043524; GO:0048589; GO:0070129; GO:0070579; GO:0070989; GO:0080111; GO:0140078; GO:1990983; GO:1990984 20979 FUN_017634 0 12 0 0 0 NA NA NA NA NA NA NA 20980 FUN_023568 20 8 67 16 15 NA NA NA NA NA NA NA 20981 FUN_023560 2911 2018 2136 4112 1309 NA NA NA NA NA NA NA 20982 FUN_023561 0 4 74 105 0 NA NA NA NA NA NA NA 20983 FUN_023562 92 58 0 0 0 NA NA NA NA NA NA NA 20984 FUN_023563 64 399 12 199 3 NA NA NA NA NA NA NA 20985 FUN_023564 842 1638 481 1167 365 NA NA NA NA NA NA NA 20986 FUN_023565 4090 3111 2693 4647 2309 NA NA NA NA NA NA NA 20987 FUN_023566 5163 3141 874 3173 2173 NA NA NA NA NA NA NA 20988 FUN_023567 0 0 0 0 16 ptg000017l:9221774-9227271 Q708S6 1.29e-22 Acid-sensing ion channel 1C (ASIC1-C) (Acid-sensing ion channel 1.3-C) (Amiloride-sensitive cation channel 2-C, neuronal-C) (ZASIC1.3) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to pH [GO:0071467]; protein homotrimerization [GO:0070207]; sodium ion transmembrane transport [GO:0035725] GO:0005261; GO:0005886; GO:0015280; GO:0035725; GO:0044736; GO:0070207; GO:0071467 20989 FUN_022219 2618 1758 1123 2620 2427 NA NA NA NA NA NA NA 20990 FUN_022218 18578 24071 11421 16734 15584 ptg000016l:6430679-6434114 Q8JIU7 3.92e-30 Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) Danio rerio (Zebrafish) (Brachydanio rerio) definitive hemopoiesis [GO:0060216]; myofibril assembly [GO:0030239]; protein targeting to membrane [GO:0006612] GO:0005634; GO:0005737; GO:0005854; GO:0006612; GO:0030239; GO:0051082; GO:0060216 20991 FUN_025249 138 165 149 106 108 NA NA NA NA NA NA NA 20992 FUN_025248 3117 6673 3464 2670 1573 NA NA NA NA NA NA NA 20993 FUN_022211 4730 3041 2242 3071 2221 NA NA NA NA NA NA NA 20994 FUN_022210 1861 2127 1075 1135 1226 NA NA NA NA NA NA NA 20995 FUN_025245 24 695 258 53 19 NA NA NA NA NA NA NA 20996 FUN_022212 1048 499 663 921 931 NA NA NA NA NA NA NA 20997 FUN_025243 318 1211 483 262 183 NA NA NA NA NA NA NA 20998 FUN_008693 607 279 294 402 451 ptg000002l:14435372-14436245 Q8IN35 5.18e-21 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 20999 FUN_022217 1921 1068 1505 2980 2715 ptg000016l:6417618-6426495 P55012 2.96e-54 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Mus musculus (Mouse) ammonium transmembrane transport [GO:0072488]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; maintenance of blood-brain barrier [GO:0035633]; mammary duct terminal end bud growth [GO:0060763]; multicellular organism growth [GO:0035264]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321] GO:0005829; GO:0005886; GO:0006813; GO:0006814; GO:0006821; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0035264; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0045795; GO:0046873; GO:0050910; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0060444; GO:0060763; GO:0061044; GO:0070634; GO:0071222; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:1902476; GO:1904450; GO:1904464; GO:1990573; GO:1990869 21000 FUN_022217 1921 1068 1505 2980 2715 ptg000016l:6417618-6426495 P55012 3.56e-44 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Mus musculus (Mouse) ammonium transmembrane transport [GO:0072488]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; maintenance of blood-brain barrier [GO:0035633]; mammary duct terminal end bud growth [GO:0060763]; multicellular organism growth [GO:0035264]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321] GO:0005829; GO:0005886; GO:0006813; GO:0006814; GO:0006821; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0035264; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0045795; GO:0046873; GO:0050910; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0060444; GO:0060763; GO:0061044; GO:0070634; GO:0071222; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:1902476; GO:1904450; GO:1904464; GO:1990573; GO:1990869 21001 FUN_022217 1921 1068 1505 2980 2715 ptg000016l:6417618-6426495 P55012 1.75e-36 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Mus musculus (Mouse) ammonium transmembrane transport [GO:0072488]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; maintenance of blood-brain barrier [GO:0035633]; mammary duct terminal end bud growth [GO:0060763]; multicellular organism growth [GO:0035264]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321] GO:0005829; GO:0005886; GO:0006813; GO:0006814; GO:0006821; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0035264; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0045795; GO:0046873; GO:0050910; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0060444; GO:0060763; GO:0061044; GO:0070634; GO:0071222; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:1902476; GO:1904450; GO:1904464; GO:1990573; GO:1990869 21002 FUN_022217 1921 1068 1505 2980 2715 ptg000016l:6417618-6426495 P55012 6.18e-22 Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2) Mus musculus (Mouse) ammonium transmembrane transport [GO:0072488]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell volume homeostasis [GO:0006884]; cellular chloride ion homeostasis [GO:0030644]; cellular potassium ion homeostasis [GO:0030007]; cellular response to chemokine [GO:1990869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to potassium ion [GO:0035865]; cellular sodium ion homeostasis [GO:0006883]; chloride ion homeostasis [GO:0055064]; chloride transmembrane transport [GO:1902476]; chloride transport [GO:0006821]; detection of mechanical stimulus involved in sensory perception of sound [GO:0050910]; gamma-aminobutyric acid signaling pathway [GO:0007214]; hyperosmotic response [GO:0006972]; inorganic anion import across plasma membrane [GO:0098658]; inorganic cation import across plasma membrane [GO:0098659]; maintenance of blood-brain barrier [GO:0035633]; mammary duct terminal end bud growth [GO:0060763]; multicellular organism growth [GO:0035264]; negative regulation of vascular wound healing [GO:0061044]; positive regulation of aspartate secretion [GO:1904450]; positive regulation of cell volume [GO:0045795]; potassium ion homeostasis [GO:0055075]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transport [GO:0006813]; regulation of matrix metallopeptidase secretion [GO:1904464]; regulation of spontaneous synaptic transmission [GO:0150003]; sodium ion homeostasis [GO:0055078]; sodium ion import across plasma membrane [GO:0098719]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; T cell chemotaxis [GO:0010818]; transepithelial ammonium transport [GO:0070634]; transepithelial chloride transport [GO:0030321] GO:0005829; GO:0005886; GO:0006813; GO:0006814; GO:0006821; GO:0006883; GO:0006884; GO:0006972; GO:0007214; GO:0008511; GO:0008519; GO:0009925; GO:0010818; GO:0015079; GO:0015377; GO:0015379; GO:0016323; GO:0016324; GO:0016328; GO:0019901; GO:0030007; GO:0030321; GO:0030644; GO:0030659; GO:0035264; GO:0035633; GO:0035725; GO:0035865; GO:0042995; GO:0043005; GO:0043025; GO:0044297; GO:0045795; GO:0046873; GO:0050910; GO:0051087; GO:0051879; GO:0055064; GO:0055075; GO:0055078; GO:0060444; GO:0060763; GO:0061044; GO:0070634; GO:0071222; GO:0071944; GO:0072488; GO:0098658; GO:0098659; GO:0098719; GO:0150003; GO:1902476; GO:1904450; GO:1904464; GO:1990573; GO:1990869 21003 FUN_022216 3649 2811 2304 5099 4732 ptg000016l:6410133-6414062 P30436 1.29e-66 Tubulin alpha chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha chain] Oncorhynchus keta (Chum salmon) (Salmo keta) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 21004 FUN_022216 3649 2811 2304 5099 4732 ptg000016l:6410133-6414062 P30436 4.94e-59 Tubulin alpha chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha chain] Oncorhynchus keta (Chum salmon) (Salmo keta) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 21005 FUN_022216 3649 2811 2304 5099 4732 ptg000016l:6410133-6414062 P30436 7.07e-44 Tubulin alpha chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha chain] Oncorhynchus keta (Chum salmon) (Salmo keta) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 21006 FUN_022216 3649 2811 2304 5099 4732 ptg000016l:6410133-6414062 P30436 1.02e-35 Tubulin alpha chain (EC 3.6.5.-) [Cleaved into: Detyrosinated tubulin alpha chain] Oncorhynchus keta (Chum salmon) (Salmo keta) microtubule-based process [GO:0007017] GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007017; GO:0016787; GO:0046872 21007 FUN_008692 172 105 30 229 189 ptg000002l:14408566-14411832 P58307 4.44e-30 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 21008 FUN_003714 43 6 0 2 30 NA NA NA NA NA NA NA 21009 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 1.03e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21010 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 7.87e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21011 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 2.3e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21012 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 7.45e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21013 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 3.39e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21014 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 1.08e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21015 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 1.88e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21016 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 8.96e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21017 FUN_032923 286 211 72 117 145 ptg000023l:37707712-37712334 Q96AY4 2.3e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21018 FUN_000624 10 38 58 41 3 NA NA NA NA NA NA NA 21019 FUN_029260 6499 6650 4206 6217 5991 ptg000022l:9677865-9688616 Q13905 9.78e-109 Rap guanine nucleotide exchange factor 1 (CRK SH3-binding GNRP) (Guanine nucleotide-releasing factor 2) (Protein C3G) Homo sapiens (Human) cellular response to cAMP [GO:0071320]; cellular response to nerve growth factor stimulus [GO:1990090]; establishment of endothelial barrier [GO:0061028]; nerve growth factor signaling pathway [GO:0038180]; nervous system development [GO:0007399]; positive regulation of GTPase activity [GO:0043547]; positive regulation of neuron projection development [GO:0010976]; Rap protein signal transduction [GO:0032486]; Ras protein signal transduction [GO:0007265]; regulation of cell junction assembly [GO:1901888]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0005085; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0007165; GO:0007169; GO:0007265; GO:0007399; GO:0010976; GO:0017124; GO:0032486; GO:0038180; GO:0043231; GO:0043547; GO:0061028; GO:0071320; GO:1901888; GO:1990090 21020 FUN_000627 88 104 215 32 17 NA NA NA NA NA NA NA 21021 FUN_029265 1 10 1 0 0 NA NA NA NA NA NA NA 21022 FUN_000621 3564 5430 2162 3292 1950 ntLink_6:5167339-5169776 P41826 0 Heat shock protein 70 A2 Anopheles albimanus (New world malaria mosquito) NA GO:0005524; GO:0140662 21023 FUN_019579 0 21 33 0 116 NA NA NA NA NA NA NA 21024 FUN_040306 3296 2120 1171 3833 3036 NA NA NA NA NA NA NA 21025 FUN_022001 112 64 106 176 116 NA NA NA NA NA NA NA 21026 FUN_024118 1064 1441 671 1529 548 NA NA NA NA NA NA NA 21027 FUN_024119 34 34 67 137 44 NA NA NA NA NA NA NA 21028 FUN_024114 0 0 3 1 6 NA NA NA NA NA NA NA 21029 FUN_024115 0 10 54 44 85 NA NA NA NA NA NA NA 21030 FUN_024116 554 494 801 497 552 NA NA NA NA NA NA NA 21031 FUN_024117 123 116 113 30 32 NA NA NA NA NA NA NA 21032 FUN_024110 39 56 27 103 97 NA NA NA NA NA NA NA 21033 FUN_024111 2659 1276 1054 2412 1353 ptg000018l:2240115-2265197 C3ZQF9 8.98e-24 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 21034 FUN_024112 25 7 4 35 24 ptg000018l:2276266-2277253 Q804X9 4.3e-41 Melanopsin-A (Opsin-4A) Gadus morhua (Atlantic cod) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 21035 FUN_024113 1417 1407 791 850 659 NA NA NA NA NA NA NA 21036 FUN_030645 9 24 11 11 7 NA NA NA NA NA NA NA 21037 FUN_030644 0 3 23 4 30 NA NA NA NA NA NA NA 21038 FUN_030646 5 0 11 7 2 NA NA NA NA NA NA NA 21039 FUN_030641 2146 2011 1446 1464 1007 NA NA NA NA NA NA NA 21040 FUN_030640 0 0 0 0 28 NA NA NA NA NA NA NA 21041 FUN_030643 460 945 375 973 609 NA NA NA NA NA NA NA 21042 FUN_038090 324 499 179 473 273 NA NA NA NA NA NA NA 21043 FUN_038094 35 0 0 8 18 NA NA NA NA NA NA NA 21044 FUN_038095 60 0 49 33 21 NA NA NA NA NA NA NA 21045 FUN_038096 10 0 0 22 0 NA NA NA NA NA NA NA 21046 FUN_038098 13596 4402 1427 7093 8256 NA NA NA NA NA NA NA 21047 FUN_038099 825 1947 662 798 355 NA NA NA NA NA NA NA 21048 FUN_004614 15 0 26 21 27 NA NA NA NA NA NA NA 21049 FUN_015099 893 952 683 889 479 ptg000009l:6119091-6120660 P27615 9.49e-91 Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (CD36 antigen-like 2) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) (CD antigen CD36) Rattus norvegicus (Rat) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular carbohydrate catabolic process [GO:0043471]; regulation of glucosylceramidase activity [GO:1905123]; sensory perception of sound [GO:0007605] GO:0001786; GO:0005044; GO:0005737; GO:0005765; GO:0005886; GO:0006622; GO:0006898; GO:0007605; GO:0010467; GO:0010976; GO:0015485; GO:0015917; GO:0019899; GO:0030666; GO:0031210; GO:0038024; GO:0042803; GO:0043202; GO:0043471; GO:0051087; GO:1905123 21050 FUN_015098 256 13 73 55 147 NA NA NA NA NA NA NA 21051 FUN_015091 1447 485 884 807 877 NA NA NA NA NA NA NA 21052 FUN_015090 210 175 232 187 173 ptg000009l:6024679-6027638 Q8K4C0 2.3e-47 Flavin-containing monooxygenase 5 (FMO 5) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (NADPH oxidase) (EC 1.6.3.1) Rattus norvegicus (Rat) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005789; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 21053 FUN_015090 210 175 232 187 173 ptg000009l:6024679-6027638 Q8K4C0 4.61e-41 Flavin-containing monooxygenase 5 (FMO 5) (Dimethylaniline monooxygenase [N-oxide-forming] 5) (EC 1.14.13.8) (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (NADPH oxidase) (EC 1.6.3.1) Rattus norvegicus (Rat) lipid metabolic process [GO:0006629]; NADPH oxidation [GO:0070995]; regulation of cholesterol metabolic process [GO:0090181]; xenobiotic metabolic process [GO:0006805] GO:0004031; GO:0004497; GO:0004499; GO:0005789; GO:0006629; GO:0006805; GO:0047822; GO:0050660; GO:0050661; GO:0070995; GO:0090181; GO:0106294 21054 FUN_015092 0 0 0 0 13 NA NA NA NA NA NA NA 21055 FUN_015095 2115 1241 906 1685 1592 NA NA NA NA NA NA NA 21056 FUN_015094 5 0 17 109 43 NA NA NA NA NA NA NA 21057 FUN_015097 2651 2180 882 1672 1144 NA NA NA NA NA NA NA 21058 FUN_015096 9198 3964 586 2895 5895 NA NA NA NA NA NA NA 21059 FUN_040262 9 2 0 0 7 NA NA NA NA NA NA NA 21060 FUN_004616 70 44 76 54 203 ntLink_8:24926446-24927706 Q6NUT3 7.56e-51 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 21061 FUN_040263 2462 1700 679 2672 1283 NA NA NA NA NA NA NA 21062 FUN_037451 1756 542 1325 1766 1135 NA NA NA NA NA NA NA 21063 FUN_037450 27 0 9 37 0 NA NA NA NA NA NA NA 21064 FUN_037453 777 788 332 1206 751 NA NA NA NA NA NA NA 21065 FUN_037452 362 270 105 369 106 ptg000026l:10680855-10686741 Q9IA95 3.44e-30 Secreted frizzled-related protein 3 (sFRP-3) (Frizzled-related protein 1) (FrzB-1) Gallus gallus (Chicken) cochlea morphogenesis [GO:0090103]; convergent extension involved in organogenesis [GO:0060029]; epithelial cell development [GO:0002064]; hepatocyte differentiation [GO:0070365]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cartilage development [GO:0061037]; negative regulation of cell development [GO:0010721]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of hepatocyte differentiation [GO:0070367]; negative regulation of Wnt signaling pathway [GO:0030178]; neural crest cell differentiation [GO:0014033]; positive regulation of apoptotic process [GO:0043065]; positive regulation of fat cell differentiation [GO:0045600]; somite development [GO:0061053]; Wnt signaling pathway [GO:0016055] GO:0002064; GO:0005576; GO:0008285; GO:0010721; GO:0014033; GO:0016055; GO:0017147; GO:0030178; GO:0030308; GO:0043065; GO:0045600; GO:0060029; GO:0061037; GO:0061053; GO:0070365; GO:0070367; GO:0090090; GO:0090103 21066 FUN_037455 1214 1186 466 1220 825 ptg000026l:10701549-10714297 Q56A55 2.43e-44 Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial sulfonylurea-receptor) (MITOSUR) Danio rerio (Zebrafish) (Brachydanio rerio) potassium ion transmembrane transport [GO:0071805] GO:0005524; GO:0005739; GO:0005743; GO:0016887; GO:0062157; GO:0071805; GO:0140359 21067 FUN_037455 1214 1186 466 1220 825 ptg000026l:10701549-10714297 Q56A55 1.43e-35 Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial sulfonylurea-receptor) (MITOSUR) Danio rerio (Zebrafish) (Brachydanio rerio) potassium ion transmembrane transport [GO:0071805] GO:0005524; GO:0005739; GO:0005743; GO:0016887; GO:0062157; GO:0071805; GO:0140359 21068 FUN_037454 316 271 72 300 121 NA NA NA NA NA NA NA 21069 FUN_037457 479 198 245 442 270 NA NA NA NA NA NA NA 21070 FUN_037456 5796 3929 2803 4307 3939 ptg000026l:10715339-10719482 Q5PQQ7 1.01e-57 LIX1-like protein Rattus norvegicus (Rat) autophagosome maturation [GO:0097352] GO:0005737; GO:0097352 21071 FUN_037456 5796 3929 2803 4307 3939 ptg000026l:10715339-10719482 Q5PQQ7 6.74e-36 LIX1-like protein Rattus norvegicus (Rat) autophagosome maturation [GO:0097352] GO:0005737; GO:0097352 21072 FUN_037459 6814 5250 3259 6101 4517 NA NA NA NA NA NA NA 21073 FUN_037458 488 413 291 270 507 NA NA NA NA NA NA NA 21074 FUN_006110 10 0 0 0 19 NA NA NA NA NA NA NA 21075 FUN_006111 8 236 32 0 369 NA NA NA NA NA NA NA 21076 FUN_006112 0 9 0 0 3 NA NA NA NA NA NA NA 21077 FUN_006114 19 0 20 13 4 ptg000001l:7898211-7899684 P48040 2.6e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Ovis aries (Sheep) NA GO:0005886; GO:0008502 21078 FUN_006115 534 496 686 1139 158 NA NA NA NA NA NA NA 21079 FUN_006116 187 346 135 197 110 NA NA NA NA NA NA NA 21080 FUN_006117 4 603 294 6 275 NA NA NA NA NA NA NA 21081 FUN_006118 1123 1740 904 3240 2264 NA NA NA NA NA NA NA 21082 FUN_006119 1884 1319 1260 2074 1133 NA NA NA NA NA NA NA 21083 FUN_004613 12 55 0 0 0 NA NA NA NA NA NA NA 21084 FUN_004612 18 22 0 7 2 NA NA NA NA NA NA NA 21085 FUN_005779 0 0 20 63 22 NA NA NA NA NA NA NA 21086 FUN_001461 390 293 212 491 659 NA NA NA NA NA NA NA 21087 FUN_001460 75 0 52 2 156 NA NA NA NA NA NA NA 21088 FUN_001463 1821 1170 1023 1597 1730 ntLink_6:12634294-12651548 Q5S006 8.27e-92 Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) Mus musculus (Mouse) autophagy [GO:0006914]; calcium-mediated signaling [GO:0019722]; cellular response to dopamine [GO:1903351]; cellular response to manganese ion [GO:0071287]; cellular response to organic cyclic compound [GO:0071407]; cellular response to oxidative stress [GO:0034599]; cellular response to starvation [GO:0009267]; determination of adult lifespan [GO:0008340]; endocytosis [GO:0006897]; endoplasmic reticulum organization [GO:0007029]; excitatory postsynaptic potential [GO:0060079]; exploration behavior [GO:0035640]; Golgi organization [GO:0007030]; GTP metabolic process [GO:0046039]; intracellular distribution of mitochondria [GO:0048312]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; locomotory exploration behavior [GO:0035641]; lysosome organization [GO:0007040]; MAPK cascade [GO:0000165]; mitochondrion localization [GO:0051646]; mitochondrion organization [GO:0007005]; negative regulation of autophagosome assembly [GO:1902902]; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902236]; negative regulation of excitatory postsynaptic potential [GO:0090394]; negative regulation of GTPase activity [GO:0034260]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of macroautophagy [GO:0016242]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein binding [GO:0032091]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein processing [GO:0010955]; negative regulation of protein targeting to mitochondrion [GO:1903215]; negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation [GO:1903125]; neuromuscular junction development [GO:0007528]; neuron death [GO:0070997]; neuron projection arborization [GO:0140058]; neuron projection morphogenesis [GO:0048812]; olfactory bulb development [GO:0021772]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; phosphorylation [GO:0016310]; positive regulation of autophagy [GO:0010508]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of dopamine receptor signaling pathway [GO:0060161]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of microglial cell activation [GO:1903980]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of programmed cell death [GO:0043068]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein autoubiquitination [GO:1902499]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; positive regulation of tumor necrosis factor production [GO:0032760]; protein autophosphorylation [GO:0046777]; protein import into nucleus [GO:0006606]; protein localization [GO:0008104]; protein localization to endoplasmic reticulum exit site [GO:0070973]; protein phosphorylation [GO:0006468]; reactive oxygen species metabolic process [GO:0072593]; regulation of autophagy [GO:0010506]; regulation of branching morphogenesis of a nerve [GO:2000172]; regulation of CAMKK-AMPK signaling cascade [GO:1905289]; regulation of canonical Wnt signaling pathway [GO:0060828]; regulation of dendritic spine morphogenesis [GO:0061001]; regulation of dopamine receptor signaling pathway [GO:0060159]; regulation of ER to Golgi vesicle-mediated transport [GO:0060628]; regulation of gene expression [GO:0010468]; regulation of kidney size [GO:0035564]; regulation of locomotion [GO:0040012]; regulation of lysosomal lumen pH [GO:0035751]; regulation of membrane potential [GO:0042391]; regulation of mitochondrial depolarization [GO:0051900]; regulation of neuroblast proliferation [GO:1902692]; regulation of neuron death [GO:1901214]; regulation of neuron maturation [GO:0014041]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein stability [GO:0031647]; regulation of retrograde transport, endosome to Golgi [GO:1905279]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle endocytosis [GO:1900242]; regulation of synaptic vesicle exocytosis [GO:2000300]; regulation of synaptic vesicle transport [GO:1902803]; response to oxidative stress [GO:0006979]; signal transduction [GO:0007165]; spermatogenesis [GO:0007283]; striatum development [GO:0021756]; synaptic vesicle recycling [GO:0036465]; tangential migration from the subventricular zone to the olfactory bulb [GO:0022028]; Wnt signalosome assembly [GO:1904887] GO:0000139; GO:0000149; GO:0000165; GO:0000287; GO:0001933; GO:0001934; GO:0003779; GO:0003924; GO:0004672; GO:0004674; GO:0004706; GO:0004709; GO:0004722; GO:0005096; GO:0005524; GO:0005525; GO:0005737; GO:0005739; GO:0005741; GO:0005743; GO:0005759; GO:0005764; GO:0005768; GO:0005783; GO:0005789; GO:0005794; GO:0005798; GO:0005802; GO:0005829; GO:0005886; GO:0005902; GO:0006468; GO:0006606; GO:0006897; GO:0006914; GO:0006979; GO:0007005; GO:0007029; GO:0007030; GO:0007040; GO:0007165; GO:0007254; GO:0007283; GO:0007528; GO:0008021; GO:0008104; GO:0008340; GO:0009267; GO:0010468; GO:0010506; GO:0010508; GO:0010738; GO:0010955; GO:0010977; GO:0014041; GO:0015631; GO:0016020; GO:0016234; GO:0016242; GO:0016301; GO:0016310; GO:0017075; GO:0018105; GO:0018107; GO:0019722; GO:0021756; GO:0021772; GO:0022028; GO:0030159; GO:0030276; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031267; GO:0031398; GO:0031410; GO:0031647; GO:0031966; GO:0032091; GO:0032092; GO:0032436; GO:0032473; GO:0032760; GO:0032839; GO:0034211; GO:0034260; GO:0034599; GO:0035556; GO:0035564; GO:0035640; GO:0035641; GO:0035751; GO:0036465; GO:0036479; GO:0040012; GO:0042391; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043195; GO:0043204; GO:0043231; GO:0043406; GO:0044325; GO:0044753; GO:0044754; GO:0044877; GO:0045121; GO:0045202; GO:0045860; GO:0046039; GO:0046777; GO:0048312; GO:0048812; GO:0051018; GO:0051646; GO:0051770; GO:0051900; GO:0051966; GO:0060079; GO:0060159; GO:0060161; GO:0060628; GO:0060828; GO:0061001; GO:0070971; GO:0070973; GO:0070997; GO:0071287; GO:0071407; GO:0072593; GO:0090263; GO:0090394; GO:0097487; GO:0098794; GO:0098978; GO:0099400; GO:0099523; GO:0106310; GO:0140058; GO:1900242; GO:1900244; GO:1901214; GO:1901215; GO:1901727; GO:1902236; GO:1902499; GO:1902692; GO:1902803; GO:1902902; GO:1903125; GO:1903206; GO:1903215; GO:1903351; GO:1903980; GO:1904713; GO:1904887; GO:1905279; GO:1905289; GO:1990904; GO:1990909; GO:2000172; GO:2000300 21089 FUN_001462 3934 4347 2208 1938 1463 NA NA NA NA NA NA NA 21090 FUN_001465 1143 930 571 901 511 ntLink_6:12655989-12661432 Q640V2 3.81e-43 E3 ubiquitin-protein ligase RMND5A (EC 2.3.2.27) (Protein RMD5 homolog A) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209] GO:0000151; GO:0000209; GO:0004842; GO:0005634; GO:0005654; GO:0005737; GO:0043161; GO:0046872; GO:0061630 21091 FUN_001464 1623 1399 1196 1145 956 ntLink_6:12654878-12655817 A5GFW7 5.37e-77 Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1) Sus scrofa (Pig) cellular response to hydroxyurea [GO:0072711]; mitotic DNA replication termination [GO:1902979]; regulation of DNA stability [GO:0097752] GO:0003677; GO:0005634; GO:0005657; GO:0072711; GO:0097752; GO:1902979 21092 FUN_001467 1328 1071 733 1168 911 NA NA NA NA NA NA NA 21093 FUN_001466 1166 277 631 288 283 NA NA NA NA NA NA NA 21094 FUN_037189 688 572 423 401 488 ptg000026l:6830327-6841932 Q76KP1 3.13e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 21095 FUN_037188 44 0 26 18 0 NA NA NA NA NA NA NA 21096 FUN_037183 4 3 0 21 13 ptg000026l:6771474-6772128 Q76KP1 1.76e-23 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 21097 FUN_037180 140 81 20 81 11 NA NA NA NA NA NA NA 21098 FUN_037187 0 18 27 0 22 NA NA NA NA NA NA NA 21099 FUN_037186 11 1 0 0 10 ptg000026l:6808764-6809711 Q76KP1 2.73e-30 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 21100 FUN_037185 1234 1622 982 1459 1263 ptg000026l:6793529-6802212 Q76KP1 4.76e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 21101 FUN_037184 37 39 78 95 183 NA NA NA NA NA NA NA 21102 FUN_004156 16813 19792 10579 9756 5649 NA NA NA NA NA NA NA 21103 FUN_042820 2091 1392 1238 1783 1420 ptg000047l:517053-525721 B4F6V6 2.4e-32 Pre-B-cell leukemia transcription factor 1 (Homeobox protein pbx1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) nervous system development [GO:0007399]; neural crest cell fate specification [GO:0014036]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0005634; GO:0005667; GO:0007399; GO:0014036; GO:0043565; GO:0045893; GO:0045944 21104 FUN_042820 2091 1392 1238 1783 1420 ptg000047l:517053-525721 B4F6V6 8.16e-25 Pre-B-cell leukemia transcription factor 1 (Homeobox protein pbx1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) nervous system development [GO:0007399]; neural crest cell fate specification [GO:0014036]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000981; GO:0005634; GO:0005667; GO:0007399; GO:0014036; GO:0043565; GO:0045893; GO:0045944 21105 FUN_042821 3843 2544 1758 3227 2264 ptg000047l:529821-540654 A2RV61 3.16e-54 GTPase-activating protein and VPS9 domain-containing protein 1 Xenopus laevis (African clawed frog) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] GO:0005085; GO:0005096; GO:0005768; GO:0005829; GO:0006897; GO:0016020; GO:0032794; GO:0043087; GO:0051223 21106 FUN_042821 3843 2544 1758 3227 2264 ptg000047l:529821-540654 A2RV61 1.61e-27 GTPase-activating protein and VPS9 domain-containing protein 1 Xenopus laevis (African clawed frog) endocytosis [GO:0006897]; regulation of GTPase activity [GO:0043087]; regulation of protein transport [GO:0051223] GO:0005085; GO:0005096; GO:0005768; GO:0005829; GO:0006897; GO:0016020; GO:0032794; GO:0043087; GO:0051223 21107 FUN_042822 5247 2905 3095 5122 4887 ptg000047l:553843-585197 Q95SX7 2.9e-40 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 21108 FUN_033600 0 0 0 0 11 NA NA NA NA NA NA NA 21109 FUN_033601 29 0 0 0 31 NA NA NA NA NA NA NA 21110 FUN_033602 8 0 0 0 63 NA NA NA NA NA NA NA 21111 FUN_033605 11 16 0 0 6 NA NA NA NA NA NA NA 21112 FUN_033606 40 8 0 19 30 NA NA NA NA NA NA NA 21113 FUN_033607 158 0 0 0 41 NA NA NA NA NA NA NA 21114 FUN_033608 1041 465 94 119 961 ptg000023l:43677552-43730944 Q0R4F1 6.98e-29 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Xenopus laevis (African clawed frog) DNA recombination [GO:0006310]; DNA repair [GO:0006281]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005739; GO:0006281; GO:0006310; GO:0016887; GO:0043139 21115 FUN_016745 2458 1666 1072 1839 1598 NA NA NA NA NA NA NA 21116 FUN_016746 45 35 30 84 23 NA NA NA NA NA NA NA 21117 FUN_042827 368 109 178 124 201 NA NA NA NA NA NA NA 21118 FUN_040099 0 0 21 0 0 NA NA NA NA NA NA NA 21119 FUN_040098 400 241 525 489 352 NA NA NA NA NA NA NA 21120 FUN_010156 0 0 4 9 0 NA NA NA NA NA NA NA 21121 FUN_031938 2833 4727 3269 3115 3139 NA NA NA NA NA NA NA 21122 FUN_031939 284 113 188 344 310 ptg000023l:26955656-26957433 Q9NRN9 1.42e-41 rRNA N6-adenosine-methyltransferase METTL5 (EC 2.1.1.-) (Methyltransferase-like protein 5) Homo sapiens (Human) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167]; stem cell differentiation [GO:0048863] GO:0003676; GO:0005634; GO:0008988; GO:0016740; GO:0031167; GO:0042995; GO:0045727; GO:0048863; GO:0098793; GO:0098794; GO:1904047 21123 FUN_031939 284 113 188 344 310 ptg000023l:26955656-26957433 Q9NRN9 1.57e-25 rRNA N6-adenosine-methyltransferase METTL5 (EC 2.1.1.-) (Methyltransferase-like protein 5) Homo sapiens (Human) positive regulation of translation [GO:0045727]; rRNA methylation [GO:0031167]; stem cell differentiation [GO:0048863] GO:0003676; GO:0005634; GO:0008988; GO:0016740; GO:0031167; GO:0042995; GO:0045727; GO:0048863; GO:0098793; GO:0098794; GO:1904047 21124 FUN_031934 473 527 350 470 375 NA NA NA NA NA NA NA 21125 FUN_031935 992 359 159 514 786 NA NA NA NA NA NA NA 21126 FUN_031936 455 223 62 204 453 NA NA NA NA NA NA NA 21127 FUN_031937 2421 5438 4152 3411 2553 NA NA NA NA NA NA NA 21128 FUN_031930 4337 7246 6424 3090 3134 NA NA NA NA NA NA NA 21129 FUN_031931 85 83 7 45 62 NA NA NA NA NA NA NA 21130 FUN_031932 923 423 934 788 876 NA NA NA NA NA NA NA 21131 FUN_031933 246 220 91 41 71 NA NA NA NA NA NA NA 21132 FUN_034371 952 1203 453 804 694 NA NA NA NA NA NA NA 21133 FUN_034370 886 939 508 967 611 NA NA NA NA NA NA NA 21134 FUN_034373 655 239 442 424 196 NA NA NA NA NA NA NA 21135 FUN_034372 1043 905 611 814 764 NA NA NA NA NA NA NA 21136 FUN_034375 4245 5158 2654 3615 2393 NA NA NA NA NA NA NA 21137 FUN_034377 1251 559 696 641 450 NA NA NA NA NA NA NA 21138 FUN_034379 3443 2274 1712 3473 3127 NA NA NA NA NA NA NA 21139 FUN_018308 61 0 11 0 0 NA NA NA NA NA NA NA 21140 FUN_018309 838 301 576 964 594 NA NA NA NA NA NA NA 21141 FUN_043622 1818 908 772 1454 1323 NA NA NA NA NA NA NA 21142 FUN_042953 264 183 259 291 507 ptg000047l:2366049-2375490 Q12933 2.21e-68 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 21143 FUN_017831 980 207 208 1077 224 ptg000012l:847930-848371 Q9D119 5.03e-22 Protein phosphatase 1 regulatory subunit 27 (Dysferlin-interacting protein 1) Mus musculus (Mouse) NA GO:0004864; GO:0019902 21144 FUN_017830 523 295 256 553 516 NA NA NA NA NA NA NA 21145 FUN_018824 1827 1582 1620 1557 1571 NA NA NA NA NA NA NA 21146 FUN_018823 21 67 23 0 0 NA NA NA NA NA NA NA 21147 FUN_017834 7567 5573 5558 4688 3547 NA NA NA NA NA NA NA 21148 FUN_017837 33 0 4 6 31 NA NA NA NA NA NA NA 21149 FUN_007049 315 237 118 430 159 NA NA NA NA NA NA NA 21150 FUN_043249 1535 758 687 1435 1410 NA NA NA NA NA NA NA 21151 FUN_043248 1295 1129 504 1156 878 NA NA NA NA NA NA NA 21152 FUN_043243 1732 497 982 1608 1146 NA NA NA NA NA NA NA 21153 FUN_043241 6571 5620 3618 5245 3891 NA NA NA NA NA NA NA 21154 FUN_007042 0 0 25 0 0 NA NA NA NA NA NA NA 21155 FUN_043246 0 0 0 9 0 NA NA NA NA NA NA NA 21156 FUN_043245 4155 3914 2094 4652 2783 NA NA NA NA NA NA NA 21157 FUN_043244 82847 94438 35483 49805 23697 ptg000047l:5890218-5894415 Q5ZJF4 7.44e-41 Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Glutathione-dependent peroxiredoxin) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) Gallus gallus (Chicken) cell redox homeostasis [GO:0045454]; lipid catabolic process [GO:0016042] GO:0004623; GO:0005615; GO:0005739; GO:0005764; GO:0005829; GO:0016042; GO:0045454; GO:0047184; GO:0051920 21158 FUN_043244 82847 94438 35483 49805 23697 ptg000047l:5890218-5894415 Q5ZJF4 7.44e-41 Peroxiredoxin-6 (EC 1.11.1.27) (1-Cys peroxiredoxin) (1-Cys PRX) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Glutathione-dependent peroxiredoxin) (Lysophosphatidylcholine acyltransferase 5) (LPC acyltransferase 5) (LPCAT-5) (Lyso-PC acyltransferase 5) (EC 2.3.1.23) (Non-selenium glutathione peroxidase) (NSGPx) Gallus gallus (Chicken) cell redox homeostasis [GO:0045454]; lipid catabolic process [GO:0016042] GO:0004623; GO:0005615; GO:0005739; GO:0005764; GO:0005829; GO:0016042; GO:0045454; GO:0047184; GO:0051920 21159 FUN_009679 0 109 29 62 18 NA NA NA NA NA NA NA 21160 FUN_013031 60 5 55 4 208 NA NA NA NA NA NA NA 21161 FUN_013032 0 0 0 20 35 NA NA NA NA NA NA NA 21162 FUN_035138 547 75 118 121 153 ptg000025l:4400354-4403411 Q8R4B8 7.7e-31 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002221; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006919; GO:0006954; GO:0007231; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070269; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 21163 FUN_035139 2064 551 429 482 397 NA NA NA NA NA NA NA 21164 FUN_030329 4 0 5 0 26 ptg000023l:10620680-10621443 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21165 FUN_035130 1490 456 886 2103 1302 NA NA NA NA NA NA NA 21166 FUN_030323 6 0 5 0 22 ptg000023l:10608524-10609287 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21167 FUN_035133 46 19 20 60 181 NA NA NA NA NA NA NA 21168 FUN_035134 5 9 25 15 2 NA NA NA NA NA NA NA 21169 FUN_030327 3 0 8 0 23 ptg000023l:10616628-10617391 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21170 FUN_030325 6 0 6 0 18 ptg000023l:10612576-10613339 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21171 FUN_041082 0 0 0 0 6 NA NA NA NA NA NA NA 21172 FUN_041081 107 16 188 620 444 NA NA NA NA NA NA NA 21173 FUN_036441 0 0 9 0 0 NA NA NA NA NA NA NA 21174 FUN_036440 15 0 20 0 13 NA NA NA NA NA NA NA 21175 FUN_036443 0 0 0 7 0 NA NA NA NA NA NA NA 21176 FUN_036445 11 0 0 0 20 NA NA NA NA NA NA NA 21177 FUN_036446 10 0 3 2 6 NA NA NA NA NA NA NA 21178 FUN_002176 16 0 0 0 37 NA NA NA NA NA NA NA 21179 FUN_002175 41 6 9 0 1 NA NA NA NA NA NA NA 21180 FUN_002170 6 0 9 21 1 NA NA NA NA NA NA NA 21181 FUN_004248 2299 3457 659 6147 1393 ntLink_8:21098278-21214536 P21328 8.87e-32 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 21182 FUN_033975 535 290 218 328 461 NA NA NA NA NA NA NA 21183 FUN_042198 0 0 0 0 47 NA NA NA NA NA NA NA 21184 FUN_042199 36 31 20 0 109 NA NA NA NA NA NA NA 21185 FUN_042190 14 7 58 20 298 NA NA NA NA NA NA NA 21186 FUN_042191 37 59 35 31 158 NA NA NA NA NA NA NA 21187 FUN_042195 1 10 0 0 6 NA NA NA NA NA NA NA 21188 FUN_033979 8472 4952 3688 10996 4010 NA NA NA NA NA NA NA 21189 FUN_023494 2751 2438 1232 1591 1077 NA NA NA NA NA NA NA 21190 FUN_031346 1 1 0 0 12 NA NA NA NA NA NA NA 21191 FUN_012849 8 0 0 0 0 NA NA NA NA NA NA NA 21192 FUN_012848 0 8 0 0 1 NA NA NA NA NA NA NA 21193 FUN_012843 2 0 2 184 41 NA NA NA NA NA NA NA 21194 FUN_012840 0 0 0 0 14 NA NA NA NA NA NA NA 21195 FUN_013800 0 0 0 0 16 NA NA NA NA NA NA NA 21196 FUN_002828 0 9 0 0 45 NA NA NA NA NA NA NA 21197 FUN_002829 25 41 42 42 15 ntLink_8:6690688-6697017 Q96AY4 1.73e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21198 FUN_002829 25 41 42 42 15 ntLink_8:6690688-6697017 Q96AY4 2.24e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21199 FUN_002829 25 41 42 42 15 ntLink_8:6690688-6697017 Q96AY4 2.29e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21200 FUN_002829 25 41 42 42 15 ntLink_8:6690688-6697017 Q96AY4 6.44e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21201 FUN_002829 25 41 42 42 15 ntLink_8:6690688-6697017 Q96AY4 1.36e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21202 FUN_002820 52 0 13 0 27 NA NA NA NA NA NA NA 21203 FUN_002821 538 0 0 211 80 ntLink_8:6628765-6643852 B8VIU6 1.97e-31 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21204 FUN_042088 8 79 7 13 0 ptg000036l:460193-462144 Q6GPE5 4.08e-140 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 21205 FUN_032218 127 132 57 57 60 ptg000023l:29842344-29844529 Q5F477 9.8e-44 Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) Gallus gallus (Chicken) lipid storage [GO:0019915] GO:0004771; GO:0005783; GO:0005811; GO:0019915 21206 FUN_032219 1688 1194 1051 1237 989 NA NA NA NA NA NA NA 21207 FUN_032211 103 14 0 0 64 NA NA NA NA NA NA NA 21208 FUN_032212 0 0 10 0 0 NA NA NA NA NA NA NA 21209 FUN_032213 143 90 53 0 198 NA NA NA NA NA NA NA 21210 FUN_032214 6537 3631 2829 3993 3605 NA NA NA NA NA NA NA 21211 FUN_032215 6329 3966 3286 5152 5770 ptg000023l:29820180-29824147 Q9BYJ9 4.15e-87 YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1) Homo sapiens (Human) immune system process [GO:0002376]; learning [GO:0007612]; memory [GO:0007613]; mRNA destabilization [GO:0061157]; organelle assembly [GO:0070925]; positive regulation of translation [GO:0045727]; positive regulation of translational initiation [GO:0045948]; regulation of antigen processing and presentation [GO:0002577]; regulation of axon guidance [GO:1902667]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of mRNA stability [GO:0043488]; stress granule assembly [GO:0034063] GO:0000932; GO:0002376; GO:0002577; GO:0003723; GO:0003729; GO:0005737; GO:0007612; GO:0007613; GO:0010494; GO:0034063; GO:0043022; GO:0043488; GO:0045727; GO:0045948; GO:0061157; GO:0070925; GO:1900271; GO:1902667; GO:1990247 21212 FUN_032216 335 256 104 104 180 NA NA NA NA NA NA NA 21213 FUN_032217 685 623 376 497 647 NA NA NA NA NA NA NA 21214 FUN_029955 0 0 7 0 0 NA NA NA NA NA NA NA 21215 FUN_029953 2 3 2 0 301 NA NA NA NA NA NA NA 21216 FUN_029950 0 0 0 8 0 NA NA NA NA NA NA NA 21217 FUN_030401 8 0 8 0 24 ptg000023l:10778709-10779472 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21218 FUN_011307 2117 1894 1424 2262 2471 NA NA NA NA NA NA NA 21219 FUN_011306 1477 1180 698 931 1049 NA NA NA NA NA NA NA 21220 FUN_000084 6 1 13 1 17 ntLink_4:90583-91346 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21221 FUN_000086 5 0 18 0 15 ntLink_4:94649-95412 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21222 FUN_011309 12 49 48 0 75 NA NA NA NA NA NA NA 21223 FUN_011308 1546 2016 959 1279 983 NA NA NA NA NA NA NA 21224 FUN_000082 7 1 14 0 19 ntLink_4:86517-87280 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21225 FUN_030408 7 0 8 1 31 ptg000023l:10798876-10799639 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 21226 FUN_037009 17 8 2 8 45 NA NA NA NA NA NA NA 21227 FUN_008703 915 466 172 665 185 NA NA NA NA NA NA NA 21228 FUN_008702 1132 846 357 632 728 NA NA NA NA NA NA NA 21229 FUN_008701 1390 1749 1014 1340 1329 NA NA NA NA NA NA NA 21230 FUN_008700 553 818 501 825 344 NA NA NA NA NA NA NA 21231 FUN_008707 1505 1386 810 1948 1371 ptg000002l:14587459-14622615 Q24270 1.79e-52 Voltage-dependent calcium channel type D subunit alpha-1 (DmCa1D) Drosophila melanogaster (Fruit fly) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; epithelial fluid transport [GO:0042045]; locomotion [GO:0040011]; muscle contraction [GO:0006936]; neuron remodeling [GO:0016322]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005891; GO:0006816; GO:0006936; GO:0008331; GO:0016322; GO:0016323; GO:0016324; GO:0019722; GO:0034765; GO:0040011; GO:0042045; GO:0046872; GO:0070588; GO:0098703 21232 FUN_008707 1505 1386 810 1948 1371 ptg000002l:14587459-14622615 Q24270 1.79e-52 Voltage-dependent calcium channel type D subunit alpha-1 (DmCa1D) Drosophila melanogaster (Fruit fly) calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; epithelial fluid transport [GO:0042045]; locomotion [GO:0040011]; muscle contraction [GO:0006936]; neuron remodeling [GO:0016322]; regulation of ion transmembrane transport [GO:0034765] GO:0005245; GO:0005891; GO:0006816; GO:0006936; GO:0008331; GO:0016322; GO:0016323; GO:0016324; GO:0019722; GO:0034765; GO:0040011; GO:0042045; GO:0046872; GO:0070588; GO:0098703 21233 FUN_008706 4613 7374 2484 5202 3856 NA NA NA NA NA NA NA 21234 FUN_008705 1286 708 639 1031 971 NA NA NA NA NA NA NA 21235 FUN_008704 2016 2124 1461 1059 1212 NA NA NA NA NA NA NA 21236 FUN_008709 668 350 312 707 373 NA NA NA NA NA NA NA 21237 FUN_008708 34 31 35 37 33 NA NA NA NA NA NA NA 21238 FUN_014870 413 338 286 255 185 NA NA NA NA NA NA NA 21239 FUN_000555 0 0 0 0 10 NA NA NA NA NA NA NA 21240 FUN_000552 34 170 67 54 92 ntLink_6:4288559-4289699 Q4G0X4 1.79e-31 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Homo sapiens (Human) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 21241 FUN_000553 130 25 46 97 92 ntLink_6:4292085-4292748 Q3URF8 1.82e-27 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 21242 FUN_041504 3404 2634 1567 2747 1650 ptg000035l:4448604-4470260 P14381 6.92e-117 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 21243 FUN_014877 505 512 580 885 388 NA NA NA NA NA NA NA 21244 FUN_014878 1438 1990 2290 2528 1105 NA NA NA NA NA NA NA 21245 FUN_014879 2075 2458 1607 2147 2184 ptg000009l:3868584-3870559 Q8LAD0 1.07e-21 Probable pyridoxal 5'-phosphate synthase subunit PDX2 (AtPDX2) (EC 4.3.3.6) (Protein EMBRYO DEFECTIVE 2407) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2) Arabidopsis thaliana (Mouse-ear cress) glutamine metabolic process [GO:0006541]; pyridoxal phosphate biosynthetic process [GO:0042823]; pyridoxine metabolic process [GO:0008614]; vitamin B6 biosynthetic process [GO:0042819] GO:0004359; GO:0005829; GO:0006541; GO:0008614; GO:0036381; GO:0042819; GO:0042823; GO:0046982; GO:1903600 21246 FUN_041508 906 595 616 773 607 NA NA NA NA NA NA NA 21247 FUN_041509 767 368 545 487 499 NA NA NA NA NA NA NA 21248 FUN_038654 0 0 0 23 0 NA NA NA NA NA NA NA 21249 FUN_000558 51 22 200 59 168 NA NA NA NA NA NA NA 21250 FUN_000559 13906 8720 6457 10963 8093 NA NA NA NA NA NA NA 21251 FUN_004973 28 0 16 12 11 ntLink_8:29407915-29409570 Q9FT73 9.37e-36 ATP-dependent DNA helicase Q-like 2 (EC 3.6.4.12) (RecQ-like protein 2) (AtRQ2) (AtRecQ2) (AtRecQl2) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016592; GO:0016887; GO:0032508; GO:0043138; GO:0046872 21252 FUN_004973 28 0 16 12 11 ntLink_8:29407915-29409570 Q9FT73 9.37e-36 ATP-dependent DNA helicase Q-like 2 (EC 3.6.4.12) (RecQ-like protein 2) (AtRQ2) (AtRecQ2) (AtRecQl2) Arabidopsis thaliana (Mouse-ear cress) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003677; GO:0005524; GO:0005694; GO:0005737; GO:0006268; GO:0006281; GO:0006310; GO:0009378; GO:0016592; GO:0016887; GO:0032508; GO:0043138; GO:0046872 21253 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21254 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21255 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21256 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21257 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21258 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21259 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21260 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 1.23e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21261 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 2.2e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21262 FUN_033162 21 43 5 44 37 ptg000023l:40567448-40571627 Q96AY4 6.11e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21263 FUN_033164 0 4 0 20 9 ptg000023l:40580901-40586359 Q96AY4 6.8e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21264 FUN_033164 0 4 0 20 9 ptg000023l:40580901-40586359 Q96AY4 1.48e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21265 FUN_033164 0 4 0 20 9 ptg000023l:40580901-40586359 Q96AY4 8.3e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21266 FUN_033164 0 4 0 20 9 ptg000023l:40580901-40586359 Q96AY4 1.3e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21267 FUN_033164 0 4 0 20 9 ptg000023l:40580901-40586359 Q96AY4 1.7e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21268 FUN_033164 0 4 0 20 9 ptg000023l:40580901-40586359 Q96AY4 6.58e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21269 FUN_038653 48 9 41 45 32 NA NA NA NA NA NA NA 21270 FUN_028603 0 0 0 0 21 NA NA NA NA NA NA NA 21271 FUN_004976 146 19 213 399 115 NA NA NA NA NA NA NA 21272 FUN_004977 1308 318 389 1098 529 NA NA NA NA NA NA NA 21273 FUN_023650 17 2 4 2 47 NA NA NA NA NA NA NA 21274 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 1.37e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21275 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 9.84e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21276 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 1.65e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21277 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 4.08e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21278 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 1.15e-125 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21279 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 8.86e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21280 FUN_023651 123 25 27 60 47 ptg000017l:10335060-10340555 Q96AY4 1.51e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21281 FUN_016658 464 567 321 644 276 NA NA NA NA NA NA NA 21282 FUN_042979 0 0 0 36 45 NA NA NA NA NA NA NA 21283 FUN_016652 1623 1181 848 686 845 NA NA NA NA NA NA NA 21284 FUN_042973 991 281 321 678 493 ptg000047l:2628000-2631978 Q60HG2 2.74e-85 Torsin-1A (Dystonia 1 protein) (Torsin ATPase 1) (EC 3.6.4.-) (Torsin family 1 member A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell adhesion [GO:0007155]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated protein folding [GO:0061077]; ER-associated misfolded protein catabolic process [GO:0071712]; intermediate filament cytoskeleton organization [GO:0045104]; neuron projection development [GO:0031175]; nuclear envelope organization [GO:0006998]; nuclear membrane organization [GO:0071763]; positive regulation of synaptic vesicle endocytosis [GO:1900244]; protein deneddylation [GO:0000338]; protein localization to nucleus [GO:0034504]; regulation of dopamine uptake involved in synaptic transmission [GO:0051584]; regulation of protein localization to cell surface [GO:2000008]; synaptic vesicle membrane organization [GO:0048499]; synaptic vesicle transport [GO:0048489]; wound healing, spreading of cells [GO:0044319] GO:0000338; GO:0005524; GO:0005635; GO:0005788; GO:0005856; GO:0006998; GO:0007155; GO:0008021; GO:0016887; GO:0030141; GO:0030426; GO:0030659; GO:0031175; GO:0031965; GO:0034504; GO:0042406; GO:0042802; GO:0044319; GO:0045104; GO:0048489; GO:0048499; GO:0051085; GO:0051584; GO:0061077; GO:0071712; GO:0071763; GO:0140662; GO:1900244; GO:2000008 21285 FUN_042970 7033 5051 5928 5748 4360 NA NA NA NA NA NA NA 21286 FUN_042971 1304 700 782 1303 1850 NA NA NA NA NA NA NA 21287 FUN_016656 426 187 329 535 657 NA NA NA NA NA NA NA 21288 FUN_042977 55 0 0 80 121 NA NA NA NA NA NA NA 21289 FUN_016654 72 54 86 31 65 NA NA NA NA NA NA NA 21290 FUN_042975 162 244 113 101 153 NA NA NA NA NA NA NA 21291 FUN_038618 19571 23657 13047 41932 15993 ptg000027l:9384459-9391473 Q6AYS4 4.12e-37 Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139]; regulation of entry of bacterium into host cell [GO:2000535]; response to bacterium [GO:0009617] GO:0004560; GO:0005615; GO:0005764; GO:0005975; GO:0006004; GO:0009617; GO:0016139; GO:2000535 21292 FUN_010557 5002 5685 4124 4986 3848 ptg000007l:163085-165747 P83941 3.05e-21 Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Stromal membrane-associated protein SMAP1B homolog) (Transcription elongation factor B polypeptide 1) Rattus norvegicus (Rat) positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; protein ubiquitination [GO:0016567]; transcription initiation at RNA polymerase II promoter [GO:0006367]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001222; GO:0006367; GO:0006511; GO:0016567; GO:0030674; GO:0030891; GO:0031466; GO:0032968; GO:0044877; GO:0070449 21293 FUN_010556 819 829 374 857 737 NA NA NA NA NA NA NA 21294 FUN_010555 1710 1330 984 2178 1650 NA NA NA NA NA NA NA 21295 FUN_010559 753 262 180 5112 482 NA NA NA NA NA NA NA 21296 FUN_010558 762 443 287 1086 456 NA NA NA NA NA NA NA 21297 FUN_017018 35 21 25 47 54 NA NA NA NA NA NA NA 21298 FUN_017011 11 0 0 4 0 NA NA NA NA NA NA NA 21299 FUN_017010 8 0 0 0 0 NA NA NA NA NA NA NA 21300 FUN_017017 0 96 88 150 0 ptg000011l:10262410-10262929 P04323 1.6e-23 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 21301 FUN_017017 0 96 88 150 0 ptg000011l:10262410-10262929 P04323 1.6e-23 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 21302 FUN_017016 0 4 6 1 20 NA NA NA NA NA NA NA 21303 FUN_017015 1229 9459 4953 5110 586 NA NA NA NA NA NA NA 21304 FUN_017014 0 0 0 0 10 NA NA NA NA NA NA NA 21305 FUN_012024 3172 649 1655 1784 1054 ptg000008l:4144135-4146937 Q9N126 3.38e-21 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 21306 FUN_012027 0 21 0 25 0 NA NA NA NA NA NA NA 21307 FUN_012026 1088 1917 985 1221 510 NA NA NA NA NA NA NA 21308 FUN_012021 881 142 364 366 339 ptg000008l:4129412-4132383 A7S5D9 2.54e-48 Iodotyrosine deiodinase (EC 1.21.1.1) (Halotyrosine dehalogenase) Nematostella vectensis (Starlet sea anemone) tyrosine metabolic process [GO:0006570] GO:0005886; GO:0006570; GO:0010181; GO:0016491; GO:0140616 21309 FUN_012021 881 142 364 366 339 ptg000008l:4129412-4132383 A7S5D9 5.68e-21 Iodotyrosine deiodinase (EC 1.21.1.1) (Halotyrosine dehalogenase) Nematostella vectensis (Starlet sea anemone) tyrosine metabolic process [GO:0006570] GO:0005886; GO:0006570; GO:0010181; GO:0016491; GO:0140616 21310 FUN_012020 1099 1133 591 1175 851 NA NA NA NA NA NA NA 21311 FUN_012022 1058 134 204 0 0 NA NA NA NA NA NA NA 21312 FUN_012029 9811 5986 5782 14358 11246 ptg000008l:4185515-4257487 P11533 3.3e-21 Dystrophin Gallus gallus (Chicken) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639] GO:0005737; GO:0005884; GO:0008270; GO:0032432; GO:0042383; GO:0045211; GO:0051015; GO:0051017; GO:0051639; GO:0120025 21313 FUN_012028 1660 3416 2445 6492 5558 ptg000008l:4167694-4181772 Q14192 2.1e-59 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 21314 FUN_012028 1660 3416 2445 6492 5558 ptg000008l:4167694-4181772 Q14192 7.65e-26 Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; heart trabecula formation [GO:0060347]; negative regulation of apoptotic process [GO:0043066]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast differentiation [GO:0001649]; response to hormone [GO:0009725]; ventricular cardiac muscle cell development [GO:0055015] GO:0000122; GO:0001649; GO:0003712; GO:0003714; GO:0005634; GO:0005654; GO:0005925; GO:0008134; GO:0009725; GO:0030018; GO:0042802; GO:0043066; GO:0043425; GO:0046872; GO:0055014; GO:0055015; GO:0060347; GO:0070885 21315 FUN_020928 908 896 308 1023 226 ptg000015l:10041804-10049671 O34363 1.38e-24 Putative L-amino-acid oxidase YobN (EC 1.4.3.2) Bacillus subtilis (strain 168) amino acid catabolic process [GO:0009063] GO:0001716; GO:0009063; GO:0016491; GO:0046592 21316 FUN_020927 202 160 46 175 62 NA NA NA NA NA NA NA 21317 FUN_020921 43 25 88 192 58 NA NA NA NA NA NA NA 21318 FUN_020920 86 53 156 186 171 NA NA NA NA NA NA NA 21319 FUN_020923 684 209 226 242 1189 NA NA NA NA NA NA NA 21320 FUN_013779 4 0 0 0 7 NA NA NA NA NA NA NA 21321 FUN_013776 0 0 0 0 10 NA NA NA NA NA NA NA 21322 FUN_013774 12 0 4 4 3 NA NA NA NA NA NA NA 21323 FUN_013775 0 7 0 0 0 NA NA NA NA NA NA NA 21324 FUN_014090 3653 834 613 937 1043 ptg000008l:31484875-31512289 O08746 1.29e-24 Matrilin-2 Mus musculus (Mouse) axon guidance [GO:0007411]; dendrite regeneration [GO:0031104]; extracellular matrix organization [GO:0030198]; glial cell migration [GO:0008347]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; response to axon injury [GO:0048678] GO:0001764; GO:0005509; GO:0005604; GO:0005615; GO:0007411; GO:0008347; GO:0030198; GO:0031012; GO:0031104; GO:0031175; GO:0048678; GO:0062023; GO:0120216 21325 FUN_014097 0 7 123 8 97 NA NA NA NA NA NA NA 21326 FUN_014094 116 17909 10585 11030 15192 NA NA NA NA NA NA NA 21327 FUN_014095 232 18316 31643 14020 28610 NA NA NA NA NA NA NA 21328 FUN_014098 299 17049 46572 26583 32706 NA NA NA NA NA NA NA 21329 FUN_014099 0 0 7 0 0 NA NA NA NA NA NA NA 21330 FUN_009425 63 13 90 49 231 NA NA NA NA NA NA NA 21331 FUN_009424 59 0 55 10 144 NA NA NA NA NA NA NA 21332 FUN_009427 42 43 36 47 75 NA NA NA NA NA NA NA 21333 FUN_009426 0 0 40 0 48 NA NA NA NA NA NA NA 21334 FUN_009421 38 6 43 42 143 ptg000004l:6649532-6660760 B8VIU6 2.65e-32 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21335 FUN_009423 0 0 0 29 28 ptg000004l:6689058-6693176 B8VIU6 8.27e-30 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21336 FUN_009422 0 0 16 33 20 ptg000004l:6666625-6669084 B8VIU6 8.07e-34 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21337 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 3.77e-57 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21338 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 1.79e-54 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21339 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 1.49e-53 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21340 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 7.49e-52 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21341 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 6.43e-50 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21342 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 3.09e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21343 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 1.6e-22 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21344 FUN_009428 32 37 0 59 19 ptg000004l:6743628-6745641 Q95218 4.89e-21 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 21345 FUN_026435 20 0 0 15 0 NA NA NA NA NA NA NA 21346 FUN_026434 0 0 0 29 0 NA NA NA NA NA NA NA 21347 FUN_026436 0 0 23 17 15 NA NA NA NA NA NA NA 21348 FUN_026430 0 0 0 35 11 NA NA NA NA NA NA NA 21349 FUN_026433 21 0 40 116 14 NA NA NA NA NA NA NA 21350 FUN_026432 18 0 10 42 83 NA NA NA NA NA NA NA 21351 FUN_026439 66 0 0 113 13 NA NA NA NA NA NA NA 21352 FUN_026438 11 3 0 77 11 NA NA NA NA NA NA NA 21353 FUN_039934 56 46 11 101 14 NA NA NA NA NA NA NA 21354 FUN_022539 2125 679 736 949 1191 NA NA NA NA NA NA NA 21355 FUN_039936 1 2 20 2 25 NA NA NA NA NA NA NA 21356 FUN_039937 3280 2172 1610 3886 3043 NA NA NA NA NA NA NA 21357 FUN_039930 314 404 617 633 925 NA NA NA NA NA NA NA 21358 FUN_039931 2409 1062 1066 2344 1238 NA NA NA NA NA NA NA 21359 FUN_039932 192 0 9 281 38 NA NA NA NA NA NA NA 21360 FUN_039933 89 0 11 59 0 NA NA NA NA NA NA NA 21361 FUN_022530 57 29 0 49 59 NA NA NA NA NA NA NA 21362 FUN_022531 74 18 32 36 60 NA NA NA NA NA NA NA 21363 FUN_022532 5983 3565 3468 5797 4868 NA NA NA NA NA NA NA 21364 FUN_022533 12 0 9 56 15 NA NA NA NA NA NA NA 21365 FUN_039938 694 698 363 531 395 NA NA NA NA NA NA NA 21366 FUN_039939 622 477 603 529 814 NA NA NA NA NA NA NA 21367 FUN_022536 11568 2328 1268 9685 2514 ptg000016l:10259404-10261319 D9IQ16 0 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21368 FUN_022537 4019 1066 1642 3753 2745 NA NA NA NA NA NA NA 21369 FUN_015323 385 304 200 486 480 ptg000009l:8836715-8843555 Q12933 5.42e-42 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 21370 FUN_015321 240 30 105 199 26 ptg000009l:8824320-8829041 B7W114 0 Cephalotoxin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21371 FUN_015320 348 194 100 415 217 ptg000009l:8814140-8817377 B7W114 0 Cephalotoxin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 21372 FUN_015327 0 0 6 0 0 NA NA NA NA NA NA NA 21373 FUN_015326 947 525 742 874 1150 NA NA NA NA NA NA NA 21374 FUN_015325 1674 836 1229 1505 2181 NA NA NA NA NA NA NA 21375 FUN_015324 12 0 0 16 0 NA NA NA NA NA NA NA 21376 FUN_015329 7 0 0 0 28 NA NA NA NA NA NA NA 21377 FUN_015328 39 22 17 49 10 NA NA NA NA NA NA NA 21378 FUN_018544 16 0 0 27 0 NA NA NA NA NA NA NA 21379 FUN_018545 0 0 7 0 11 NA NA NA NA NA NA NA 21380 FUN_018547 37 0 13 22 7 ptg000012l:10696353-10703517 D3YXG0 5.68e-76 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 21381 FUN_018540 957 817 593 759 299 NA NA NA NA NA NA NA 21382 FUN_018541 1099 685 736 1033 679 NA NA NA NA NA NA NA 21383 FUN_018542 779 375 370 383 321 NA NA NA NA NA NA NA 21384 FUN_018543 278 370 192 483 412 NA NA NA NA NA NA NA 21385 FUN_018548 0 0 19 0 0 NA NA NA NA NA NA NA 21386 FUN_008602 287 59 234 141 693 NA NA NA NA NA NA NA 21387 FUN_025162 3 0 2 1 18 NA NA NA NA NA NA NA 21388 FUN_025163 10 0 0 0 17 NA NA NA NA NA NA NA 21389 FUN_025160 0 12 0 18 9 NA NA NA NA NA NA NA 21390 FUN_025161 0 4 1 39 25 NA NA NA NA NA NA NA 21391 FUN_017848 8426 4873 3545 5752 4393 NA NA NA NA NA NA NA 21392 FUN_018896 59 288 0 9 61 NA NA NA NA NA NA NA 21393 FUN_017841 1234 666 574 1534 1499 NA NA NA NA NA NA NA 21394 FUN_018894 43 3 81 0 37 NA NA NA NA NA NA NA 21395 FUN_017843 1879 985 953 1317 1819 NA NA NA NA NA NA NA 21396 FUN_017845 3292 1138 1400 2353 1947 NA NA NA NA NA NA NA 21397 FUN_017846 1985 971 625 874 494 NA NA NA NA NA NA NA 21398 FUN_043015 1578 874 890 1421 892 NA NA NA NA NA NA NA 21399 FUN_011572 70 0 0 0 0 NA NA NA NA NA NA NA 21400 FUN_031838 1001 494 840 695 1318 NA NA NA NA NA NA NA 21401 FUN_031835 399 471 407 613 289 NA NA NA NA NA NA NA 21402 FUN_031834 231 180 177 488 249 ptg000023l:25890673-25893580 Q8VEB6 9.18e-41 Zinc phosphodiesterase ELAC protein 1 (EC 3.1.26.11) (ElaC homolog protein 1) (Ribonuclease Z 1) (RNase Z 1) (tRNA 3 endonuclease 1) (tRNase Z 1) Mus musculus (Mouse) tRNA 3'-trailer cleavage [GO:0042779] GO:0005634; GO:0005654; GO:0005829; GO:0042779; GO:0042781; GO:0046872 21403 FUN_031837 227 14 186 21 295 NA NA NA NA NA NA NA 21404 FUN_031836 169 12 120 22 269 NA NA NA NA NA NA NA 21405 FUN_031831 191 208 97 247 66 NA NA NA NA NA NA NA 21406 FUN_031830 93 35 144 54 129 ptg000023l:25848318-25854094 Q9CUX1 2.75e-21 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 21407 FUN_031830 93 35 144 54 129 ptg000023l:25848318-25854094 Q9CUX1 2.75e-21 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 21408 FUN_031830 93 35 144 54 129 ptg000023l:25848318-25854094 Q9CUX1 2.75e-21 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 21409 FUN_031833 724 358 178 262 171 NA NA NA NA NA NA NA 21410 FUN_031832 295 355 66 297 35 ptg000023l:25860793-25887552 P08548 4.84e-65 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 21411 FUN_043019 1793 1021 954 1678 1414 NA NA NA NA NA NA NA 21412 FUN_038681 94 180 113 99 184 ptg000027l:10134835-10138260 Q5RCY5 3.64e-30 Protein asteroid homolog 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004518 21413 FUN_038680 0 33 0 0 19 ptg000027l:10074951-10126887 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21414 FUN_038680 0 33 0 0 19 ptg000027l:10074951-10126887 Q96AY4 2.71e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21415 FUN_038680 0 33 0 0 19 ptg000027l:10074951-10126887 Q96AY4 7.85e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21416 FUN_038680 0 33 0 0 19 ptg000027l:10074951-10126887 Q96AY4 6.51e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21417 FUN_038683 1170 142 1020 606 108 ptg000027l:10155197-10160784 Q2TB18 5.88e-36 Protein asteroid homolog 1 Homo sapiens (Human) NA GO:0004518 21418 FUN_038682 1693 1118 506 838 1133 NA NA NA NA NA NA NA 21419 FUN_038685 1206 672 664 800 1071 ptg000027l:10169774-10193737 Q96QU8 8.25e-36 Exportin-6 (Exp6) (Ran-binding protein 20) Homo sapiens (Human) protein export from nucleus [GO:0006611] GO:0005049; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006611; GO:0031267; GO:0032991 21420 FUN_038685 1206 672 664 800 1071 ptg000027l:10169774-10193737 Q96QU8 2.23e-28 Exportin-6 (Exp6) (Ran-binding protein 20) Homo sapiens (Human) protein export from nucleus [GO:0006611] GO:0005049; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006611; GO:0031267; GO:0032991 21421 FUN_038685 1206 672 664 800 1071 ptg000027l:10169774-10193737 Q96QU8 1.37e-21 Exportin-6 (Exp6) (Ran-binding protein 20) Homo sapiens (Human) protein export from nucleus [GO:0006611] GO:0005049; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0006611; GO:0031267; GO:0032991 21422 FUN_038689 0 0 0 150 0 NA NA NA NA NA NA NA 21423 FUN_038688 13195 12793 8723 13905 9763 ptg000027l:10212958-10230600 Q99798 1.32e-36 Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) Homo sapiens (Human) citrate metabolic process [GO:0006101]; generation of precursor metabolites and energy [GO:0006091]; isocitrate metabolic process [GO:0006102]; liver development [GO:0001889]; response to isolation stress [GO:0035900]; tricarboxylic acid cycle [GO:0006099] GO:0001889; GO:0003994; GO:0005506; GO:0005739; GO:0005759; GO:0005829; GO:0006091; GO:0006099; GO:0006101; GO:0006102; GO:0035900; GO:0047780; GO:0051538; GO:0051539 21424 FUN_014846 1613 793 1054 2721 2204 ptg000009l:3634970-3671591 Q04690 3.29e-21 Neurofibromin (Neurofibromatosis-related protein NF-1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; astrocyte differentiation [GO:0048708]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; endothelial cell proliferation [GO:0001935]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fibroblast proliferation [GO:0048144]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glial cell proliferation [GO:0014009]; glutamate secretion, neurotransmission [GO:0061535]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; leukocyte apoptotic process [GO:0071887]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; mast cell apoptotic process [GO:0033024]; mast cell proliferation [GO:0070662]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; myeloid cell apoptotic process [GO:0033028]; myeloid leukocyte migration [GO:0097529]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; neural tube development [GO:0021915]; neuroblast proliferation [GO:0007405]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; observational learning [GO:0098597]; oligodendrocyte differentiation [GO:0048709]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte apoptotic process [GO:2000108]; positive regulation of mast cell apoptotic process [GO:0033027]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron projection development [GO:0010976]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; postsynaptic signal transduction [GO:0098926]; protein import into nucleus [GO:0006606]; Rac protein signal transduction [GO:0016601]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell population proliferation [GO:0042127]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of MAPK cascade [GO:0043408]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of neuron differentiation [GO:0045664]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; Schwann cell migration [GO:0036135]; Schwann cell proliferation [GO:0014010]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; vascular associated smooth muscle cell migration [GO:1904738]; vascular associated smooth muscle cell proliferation [GO:1990874]; visual learning [GO:0008542]; wound healing [GO:0042060] GO:0000165; GO:0001525; GO:0001649; GO:0001656; GO:0001666; GO:0001889; GO:0001935; GO:0001937; GO:0001938; GO:0001952; GO:0001953; GO:0002686; GO:0005096; GO:0005634; GO:0005730; GO:0005737; GO:0005886; GO:0006469; GO:0006606; GO:0006915; GO:0007154; GO:0007265; GO:0007269; GO:0007405; GO:0007406; GO:0007420; GO:0007422; GO:0007507; GO:0007519; GO:0008017; GO:0008283; GO:0008285; GO:0008429; GO:0008542; GO:0008625; GO:0010468; GO:0010626; GO:0010976; GO:0014009; GO:0014010; GO:0014044; GO:0014065; GO:0014069; GO:0016020; GO:0016477; GO:0016525; GO:0016601; GO:0021510; GO:0021764; GO:0021897; GO:0021915; GO:0021987; GO:0022011; GO:0030036; GO:0030198; GO:0030199; GO:0030316; GO:0030325; GO:0030336; GO:0030424; GO:0030425; GO:0031210; GO:0032228; GO:0032991; GO:0033024; GO:0033027; GO:0033028; GO:0033034; GO:0034605; GO:0035021; GO:0036135; GO:0042060; GO:0042127; GO:0042308; GO:0043005; GO:0043065; GO:0043087; GO:0043407; GO:0043408; GO:0043409; GO:0043473; GO:0043525; GO:0043535; GO:0043547; GO:0045124; GO:0045545; GO:0045664; GO:0045671; GO:0045685; GO:0045762; GO:0045765; GO:0046580; GO:0046929; GO:0048144; GO:0048147; GO:0048169; GO:0048485; GO:0048593; GO:0048708; GO:0048709; GO:0048712; GO:0048715; GO:0048745; GO:0048820; GO:0048844; GO:0048853; GO:0050890; GO:0051402; GO:0060253; GO:0061534; GO:0061535; GO:0070662; GO:0070667; GO:0071887; GO:0072089; GO:0097192; GO:0097529; GO:0098597; GO:0098793; GO:0098926; GO:0098978; GO:0099159; GO:0099175; GO:1900148; GO:1900271; GO:1904707; GO:1904738; GO:1904753; GO:1990874; GO:2000108; GO:2000647; GO:2001241 21425 FUN_014846 1613 793 1054 2721 2204 ptg000009l:3634970-3671591 Q04690 3.29e-21 Neurofibromin (Neurofibromatosis-related protein NF-1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; adrenal gland development [GO:0030325]; amygdala development [GO:0021764]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; astrocyte differentiation [GO:0048708]; brain development [GO:0007420]; camera-type eye morphogenesis [GO:0048593]; cell communication [GO:0007154]; cell migration [GO:0016477]; cell population proliferation [GO:0008283]; cellular response to heat [GO:0034605]; cerebral cortex development [GO:0021987]; cognition [GO:0050890]; collagen fibril organization [GO:0030199]; endothelial cell proliferation [GO:0001935]; extracellular matrix organization [GO:0030198]; extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; fibroblast proliferation [GO:0048144]; forebrain astrocyte development [GO:0021897]; forebrain morphogenesis [GO:0048853]; gamma-aminobutyric acid secretion, neurotransmission [GO:0061534]; glial cell proliferation [GO:0014009]; glutamate secretion, neurotransmission [GO:0061535]; hair follicle maturation [GO:0048820]; heart development [GO:0007507]; leukocyte apoptotic process [GO:0071887]; liver development [GO:0001889]; MAPK cascade [GO:0000165]; mast cell apoptotic process [GO:0033024]; mast cell proliferation [GO:0070662]; metanephros development [GO:0001656]; myelination in peripheral nervous system [GO:0022011]; myeloid cell apoptotic process [GO:0033028]; myeloid leukocyte migration [GO:0097529]; negative regulation of angiogenesis [GO:0016525]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-matrix adhesion [GO:0001953]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of glial cell proliferation [GO:0060253]; negative regulation of leukocyte migration [GO:0002686]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of neuroblast proliferation [GO:0007406]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of oligodendrocyte differentiation [GO:0048715]; negative regulation of osteoclast differentiation [GO:0045671]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of Rac protein signal transduction [GO:0035021]; negative regulation of Ras protein signal transduction [GO:0046580]; negative regulation of Schwann cell migration [GO:1900148]; negative regulation of Schwann cell proliferation [GO:0010626]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; neural tube development [GO:0021915]; neuroblast proliferation [GO:0007405]; neuron apoptotic process [GO:0051402]; neurotransmitter secretion [GO:0007269]; observational learning [GO:0098597]; oligodendrocyte differentiation [GO:0048709]; osteoblast differentiation [GO:0001649]; osteoclast differentiation [GO:0030316]; peripheral nervous system development [GO:0007422]; phosphatidylinositol 3-kinase signaling [GO:0014065]; pigmentation [GO:0043473]; positive regulation of adenylate cyclase activity [GO:0045762]; positive regulation of apoptotic process [GO:0043065]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of GTPase activity [GO:0043547]; positive regulation of leukocyte apoptotic process [GO:2000108]; positive regulation of mast cell apoptotic process [GO:0033027]; positive regulation of myeloid cell apoptotic process [GO:0033034]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of neuron projection development [GO:0010976]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; postsynaptic signal transduction [GO:0098926]; protein import into nucleus [GO:0006606]; Rac protein signal transduction [GO:0016601]; Ras protein signal transduction [GO:0007265]; regulation of angiogenesis [GO:0045765]; regulation of blood vessel endothelial cell migration [GO:0043535]; regulation of bone resorption [GO:0045124]; regulation of cell population proliferation [GO:0042127]; regulation of cell-matrix adhesion [GO:0001952]; regulation of gene expression [GO:0010468]; regulation of glial cell differentiation [GO:0045685]; regulation of GTPase activity [GO:0043087]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of long-term synaptic potentiation [GO:1900271]; regulation of MAPK cascade [GO:0043408]; regulation of modification of postsynaptic structure [GO:0099159]; regulation of neuron differentiation [GO:0045664]; regulation of postsynapse organization [GO:0099175]; regulation of synaptic transmission, GABAergic [GO:0032228]; response to hypoxia [GO:0001666]; Schwann cell development [GO:0014044]; Schwann cell migration [GO:0036135]; Schwann cell proliferation [GO:0014010]; skeletal muscle tissue development [GO:0007519]; smooth muscle tissue development [GO:0048745]; spinal cord development [GO:0021510]; stem cell proliferation [GO:0072089]; sympathetic nervous system development [GO:0048485]; vascular associated smooth muscle cell migration [GO:1904738]; vascular associated smooth muscle cell proliferation [GO:1990874]; visual learning [GO:0008542]; wound healing [GO:0042060] GO:0000165; GO:0001525; GO:0001649; GO:0001656; GO:0001666; GO:0001889; GO:0001935; GO:0001937; GO:0001938; GO:0001952; GO:0001953; GO:0002686; GO:0005096; GO:0005634; GO:0005730; GO:0005737; GO:0005886; GO:0006469; GO:0006606; GO:0006915; GO:0007154; GO:0007265; GO:0007269; GO:0007405; GO:0007406; GO:0007420; GO:0007422; GO:0007507; GO:0007519; GO:0008017; GO:0008283; GO:0008285; GO:0008429; GO:0008542; GO:0008625; GO:0010468; GO:0010626; GO:0010976; GO:0014009; GO:0014010; GO:0014044; GO:0014065; GO:0014069; GO:0016020; GO:0016477; GO:0016525; GO:0016601; GO:0021510; GO:0021764; GO:0021897; GO:0021915; GO:0021987; GO:0022011; GO:0030036; GO:0030198; GO:0030199; GO:0030316; GO:0030325; GO:0030336; GO:0030424; GO:0030425; GO:0031210; GO:0032228; GO:0032991; GO:0033024; GO:0033027; GO:0033028; GO:0033034; GO:0034605; GO:0035021; GO:0036135; GO:0042060; GO:0042127; GO:0042308; GO:0043005; GO:0043065; GO:0043087; GO:0043407; GO:0043408; GO:0043409; GO:0043473; GO:0043525; GO:0043535; GO:0043547; GO:0045124; GO:0045545; GO:0045664; GO:0045671; GO:0045685; GO:0045762; GO:0045765; GO:0046580; GO:0046929; GO:0048144; GO:0048147; GO:0048169; GO:0048485; GO:0048593; GO:0048708; GO:0048709; GO:0048712; GO:0048715; GO:0048745; GO:0048820; GO:0048844; GO:0048853; GO:0050890; GO:0051402; GO:0060253; GO:0061534; GO:0061535; GO:0070662; GO:0070667; GO:0071887; GO:0072089; GO:0097192; GO:0097529; GO:0098597; GO:0098793; GO:0098926; GO:0098978; GO:0099159; GO:0099175; GO:1900148; GO:1900271; GO:1904707; GO:1904738; GO:1904753; GO:1990874; GO:2000108; GO:2000647; GO:2001241 21426 FUN_044259 1 2 20 12 20 NA NA NA NA NA NA NA 21427 FUN_044258 0 0 4 2 8 NA NA NA NA NA NA NA 21428 FUN_035338 0 0 46 55 9 ptg000025l:6526165-6529021 O95685 8.01e-24 Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0004722; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0042587; GO:0043231; GO:2001069 21429 FUN_035339 17303 35467 20391 23078 9810 ptg000025l:6535511-6537475 O95685 1.01e-24 Protein phosphatase 1 regulatory subunit 3D (Protein phosphatase 1 regulatory subunit 6) (PP1 subunit R6) (Protein phosphatase 1-binding subunit R6) Homo sapiens (Human) glycogen metabolic process [GO:0005977]; regulation of glycogen biosynthetic process [GO:0005979]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0004722; GO:0005977; GO:0005979; GO:0005981; GO:0008157; GO:0042587; GO:0043231; GO:2001069 21430 FUN_044251 1 2 4 7 10 NA NA NA NA NA NA NA 21431 FUN_044250 1 2 11 7 66 NA NA NA NA NA NA NA 21432 FUN_035334 36 45 27 82 44 ptg000025l:6503877-6505080 Q28997 6.8e-47 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Sus scrofa (Pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; blood vessel diameter maintenance [GO:0097746]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; receptor-mediated endocytosis [GO:0006898]; regulation of smooth muscle contraction [GO:0006940] GO:0002032; GO:0004941; GO:0005769; GO:0005794; GO:0005886; GO:0006898; GO:0006940; GO:0007189; GO:0007190; GO:0042803; GO:0043235; GO:0043410; GO:0051380; GO:0097746; GO:1901098; GO:1904504 21433 FUN_035335 0 0 27 3 69 NA NA NA NA NA NA NA 21434 FUN_035332 919 688 162 407 261 NA NA NA NA NA NA NA 21435 FUN_044256 3 6 56 22 134 NA NA NA NA NA NA NA 21436 FUN_001212 10258 10700 10773 9039 7581 NA NA NA NA NA NA NA 21437 FUN_001932 102 109 154 516 173 ntLink_6:17948475-17967401 P00765 8.17e-29 Trypsin-1 (EC 3.4.21.4) (Trypsin I) Astacus astacus (Noble crayfish) (Astacus fluviatilis) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872 21438 FUN_001935 0 8 0 30 4 NA NA NA NA NA NA NA 21439 FUN_039489 0 0 4 0 6 NA NA NA NA NA NA NA 21440 FUN_039484 0 0 0 0 12 NA NA NA NA NA NA NA 21441 FUN_039480 0 0 0 322 0 NA NA NA NA NA NA NA 21442 FUN_039481 2 4 7 584 52 NA NA NA NA NA NA NA 21443 FUN_039482 0 0 10 0 38 NA NA NA NA NA NA NA 21444 FUN_036127 0 0 0 0 49 NA NA NA NA NA NA NA 21445 FUN_035480 545 113 100 509 249 ptg000025l:7883928-7886505 Q70JA7 5.59e-90 Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0008376; GO:0030206; GO:0032580; GO:0046872; GO:0047238; GO:0050510 21446 FUN_035480 545 113 100 509 249 ptg000025l:7883928-7886505 Q70JA7 5.75e-68 Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0008376; GO:0030206; GO:0032580; GO:0046872; GO:0047238; GO:0050510 21447 FUN_035481 60 53 79 142 43 ptg000025l:7889785-7891092 Q70JA7 1.94e-70 Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206] GO:0000139; GO:0008376; GO:0030206; GO:0032580; GO:0046872; GO:0047238; GO:0050510 21448 FUN_035482 112 1143 167 390 415 ptg000025l:7893024-7895920 Q9QZ85 2.77e-39 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 21449 FUN_035483 0 270 2 0 22 NA NA NA NA NA NA NA 21450 FUN_035484 9 49 3 14 32 NA NA NA NA NA NA NA 21451 FUN_035486 319 314 15 64 73 ptg000025l:7903357-7909707 Q9QZ85 1.99e-37 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 21452 FUN_035487 0 56 0 0 0 ptg000025l:7916252-7919708 Q3T9E4 2.21e-41 T-cell-specific guanine nucleotide triphosphate-binding protein 2 (EC 3.6.5.-) (Interferon-gamma-inducible GTPase Ifggb6 protein) (T-cell-specific guanine nucleotide triphosphate-binding protein) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; defense response [GO:0006952]; innate immune response [GO:0045087] GO:0003924; GO:0005525; GO:0005789; GO:0005794; GO:0006952; GO:0035458; GO:0045087 21453 FUN_035488 67 56 11 19 17 ptg000025l:7924607-7928798 Q9QZ85 3.86e-36 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 21454 FUN_035488 67 56 11 19 17 ptg000025l:7924607-7928798 Q9QZ85 3.86e-36 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 21455 FUN_035489 1162 1025 491 639 856 ptg000025l:7935952-7940377 Q9QZ85 1.81e-37 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 21456 FUN_031302 3 27 0 0 95 NA NA NA NA NA NA NA 21457 FUN_031301 0 10 0 4 20 NA NA NA NA NA NA NA 21458 FUN_031307 2591 1528 1215 1696 1099 ptg000023l:19202471-19229797 Q6ITT3 8.37e-67 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 21459 FUN_031306 83 129 26 31 43 NA NA NA NA NA NA NA 21460 FUN_031305 2690 2737 1575 3091 1820 ptg000023l:19154607-19174671 Q9W0Y8 4.78e-65 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 21461 FUN_031305 2690 2737 1575 3091 1820 ptg000023l:19154607-19174671 Q9W0Y8 1.65e-27 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 21462 FUN_031304 79 71 46 109 23 NA NA NA NA NA NA NA 21463 FUN_031309 98 84 99 100 115 NA NA NA NA NA NA NA 21464 FUN_031308 33 13 0 15 8 ptg000023l:19231790-19233968 Q6ITT3 7.24e-63 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 21465 FUN_014841 89 36 45 88 124 NA NA NA NA NA NA NA 21466 FUN_014633 1623 1568 707 942 756 NA NA NA NA NA NA NA 21467 FUN_037838 19762 24583 9774 17504 16184 NA NA NA NA NA NA NA 21468 FUN_027281 0 0 0 0 57 ptg000021l:2978663-2988463 Q96DM1 5.72e-61 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 21469 FUN_027285 496 483 287 327 332 NA NA NA NA NA NA NA 21470 FUN_027284 0 35 20 36 2 NA NA NA NA NA NA NA 21471 FUN_027287 0 7 0 0 0 NA NA NA NA NA NA NA 21472 FUN_027286 0 56 96 69 4 NA NA NA NA NA NA NA 21473 FUN_027288 0 0 91 0 0 NA NA NA NA NA NA NA 21474 FUN_024442 2745 1981 2522 3162 3139 NA NA NA NA NA NA NA 21475 FUN_008012 67 4 19 32 160 NA NA NA NA NA NA NA 21476 FUN_037226 672 224 238 488 447 NA NA NA NA NA NA NA 21477 FUN_037227 886 732 684 746 1144 NA NA NA NA NA NA NA 21478 FUN_037224 550 445 1024 779 1090 NA NA NA NA NA NA NA 21479 FUN_037225 196 113 103 114 195 NA NA NA NA NA NA NA 21480 FUN_037222 1415 749 1043 1415 706 NA NA NA NA NA NA NA 21481 FUN_037223 663 957 757 147 413 NA NA NA NA NA NA NA 21482 FUN_037220 82 67 29 0 44 NA NA NA NA NA NA NA 21483 FUN_037221 1308 1397 1167 1062 1067 NA NA NA NA NA NA NA 21484 FUN_024446 66 128 80 102 149 ptg000018l:6466403-6468785 Q8C1Z8 1.55e-66 tRNA methyltransferase 10 homolog A (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 2) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10A) Mus musculus (Mouse) magnesium ion homeostasis [GO:0010960]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0000049; GO:0002939; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0009019; GO:0010960; GO:0015629; GO:0030488; GO:0052905 21485 FUN_037834 1975 1503 871 1586 1394 NA NA NA NA NA NA NA 21486 FUN_037228 8506 7736 3839 6245 5764 NA NA NA NA NA NA NA 21487 FUN_024447 1714 1913 933 1452 1044 ptg000018l:6469019-6469688 O18883 4.47e-80 Thioredoxin domain-containing protein 9 (Protein 1-4) Bos taurus (Bovine) NA GO:0005634; GO:0005737; GO:0005815; GO:0030496 21488 FUN_006701 519 1840 2657 3467 1921 NA NA NA NA NA NA NA 21489 FUN_006700 376 1122 487 80 439 NA NA NA NA NA NA NA 21490 FUN_006703 79 4 24 13 0 NA NA NA NA NA NA NA 21491 FUN_006702 1622 2518 907 892 945 NA NA NA NA NA NA NA 21492 FUN_006705 3 0 16 0 0 NA NA NA NA NA NA NA 21493 FUN_006704 2392 4406 2058 1566 1610 ptg000001l:15811755-15822295 E9Q236 1.53e-64 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 21494 FUN_006704 2392 4406 2058 1566 1610 ptg000001l:15811755-15822295 E9Q236 3.27e-51 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 21495 FUN_006704 2392 4406 2058 1566 1610 ptg000001l:15811755-15822295 E9Q236 2.11e-24 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 21496 FUN_006706 754 566 426 341 680 NA NA NA NA NA NA NA 21497 FUN_006709 10 2 0 0 2 NA NA NA NA NA NA NA 21498 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 3.21e-38 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21499 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 3.21e-38 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21500 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 1.35e-31 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21501 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 1.35e-31 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21502 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 1.35e-31 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21503 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 1.5e-25 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21504 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 9.98e-25 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21505 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 9.98e-25 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21506 FUN_024445 3503 2140 2310 4017 2673 ptg000018l:6424641-6464801 Q8WN95 4.01e-21 Inositol 1,4,5-trisphosphate receptor type 3 (IP3 receptor isoform 3) (IP3R 3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) Bos taurus (Bovine) calcium ion transport [GO:0006816] GO:0005220; GO:0005789; GO:0005791; GO:0006816; GO:0015278; GO:0030141; GO:0030658; GO:0070679 21507 FUN_026886 11 0 0 0 0 NA NA NA NA NA NA NA 21508 FUN_026883 0 0 0 0 35 NA NA NA NA NA NA NA 21509 FUN_024449 66 0 9 79 102 ptg000018l:6494705-6509294 O75899 1.12e-22 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) (HG20) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; gamma-aminobutyric acid signaling pathway [GO:0007214]; negative regulation of adenylate cyclase activity [GO:0007194]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007186; GO:0007193; GO:0007194; GO:0007214; GO:0007268; GO:0038039; GO:0043005; GO:0045211; GO:0046982; GO:0051932; GO:0150099; GO:1902710; GO:1902712 21510 FUN_032760 85 112 136 429 53 NA NA NA NA NA NA NA 21511 FUN_032761 0 8 16 24 7 NA NA NA NA NA NA NA 21512 FUN_032763 10 7 0 0 0 NA NA NA NA NA NA NA 21513 FUN_032765 74 90 57 82 0 NA NA NA NA NA NA NA 21514 FUN_032766 39 31 91 5 40 NA NA NA NA NA NA NA 21515 FUN_032767 0 0 0 0 7 NA NA NA NA NA NA NA 21516 FUN_032768 0 0 0 7 0 NA NA NA NA NA NA NA 21517 FUN_044042 442 1933 3087 2089 3070 NA NA NA NA NA NA NA 21518 FUN_044043 493 2269 3361 2325 3799 NA NA NA NA NA NA NA 21519 FUN_014364 282 26 70 341 382 NA NA NA NA NA NA NA 21520 FUN_044046 4 1 11 0 61 NA NA NA NA NA NA NA 21521 FUN_014367 0 0 0 6 0 NA NA NA NA NA NA NA 21522 FUN_044049 10 18 13 15 44 NA NA NA NA NA NA NA 21523 FUN_004419 882 887 351 531 489 NA NA NA NA NA NA NA 21524 FUN_004418 2243 2247 1403 3214 2212 NA NA NA NA NA NA NA 21525 FUN_004413 38 77 36 23 42 NA NA NA NA NA NA NA 21526 FUN_004412 18 10 7 27 71 NA NA NA NA NA NA NA 21527 FUN_004411 17 14 12 0 44 NA NA NA NA NA NA NA 21528 FUN_004410 70 27 75 19 20 NA NA NA NA NA NA NA 21529 FUN_004417 0 14 0 0 7 NA NA NA NA NA NA NA 21530 FUN_004415 1496 726 817 1253 1294 NA NA NA NA NA NA NA 21531 FUN_004414 1497 840 457 845 793 NA NA NA NA NA NA NA 21532 FUN_016046 331 665 508 712 1026 NA NA NA NA NA NA NA 21533 FUN_002718 286 306 148 356 252 ntLink_8:5685261-5686486 Q96GS4 9.67e-30 BLOC-1-related complex subunit 6 (Lysosome-dispersing protein) (Lyspersin) Homo sapiens (Human) lysosome localization [GO:0032418]; organelle transport along microtubule [GO:0072384]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196] GO:0032418; GO:0042802; GO:0051036; GO:0062196; GO:0072384; GO:0098574; GO:0099078 21534 FUN_002719 609 403 390 532 924 NA NA NA NA NA NA NA 21535 FUN_002716 198 129 225 226 190 NA NA NA NA NA NA NA 21536 FUN_002714 2383 2378 3807 4265 5213 NA NA NA NA NA NA NA 21537 FUN_002715 505 128 346 662 483 NA NA NA NA NA NA NA 21538 FUN_002712 720 575 231 570 288 NA NA NA NA NA NA NA 21539 FUN_002713 166 109 0 42 37 NA NA NA NA NA NA NA 21540 FUN_002710 225 184 86 41 22 NA NA NA NA NA NA NA 21541 FUN_002711 1648 3237 895 1774 1004 NA NA NA NA NA NA NA 21542 FUN_001168 225 253 127 332 140 NA NA NA NA NA NA NA 21543 FUN_001169 2203 1557 1049 2395 1678 NA NA NA NA NA NA NA 21544 FUN_008107 1948 1875 1258 1155 692 ptg000002l:8091508-8097097 A0A1W2P872 9.43e-45 RNA-binding protein Nova-2 Mus musculus (Mouse) central nervous system neuron development [GO:0021954]; mRNA processing [GO:0006397]; negative regulation of cold-induced thermogenesis [GO:0120163]; neuron differentiation [GO:0030182]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; regulation of axon guidance [GO:1902667]; regulation of RNA metabolic process [GO:0051252]; RNA splicing [GO:0008380] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0006397; GO:0008380; GO:0021954; GO:0030182; GO:0051252; GO:0120163; GO:1902667; GO:1990825 21545 FUN_001160 1820 1170 1083 1841 1751 ntLink_6:9221504-9231233 P97742 2.87e-23 Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Mus musculus (Mouse) carnitine metabolic process [GO:0009437]; cellular response to fatty acid [GO:0071398]; eating behavior [GO:0042755]; epithelial cell differentiation [GO:0030855]; fatty acid beta-oxidation [GO:0006635]; fatty acid metabolic process [GO:0006631]; glucose metabolic process [GO:0006006]; lipid localization [GO:0010876]; liver regeneration [GO:0097421]; long-chain fatty acid metabolic process [GO:0001676]; positive regulation of fatty acid beta-oxidation [GO:0032000]; regulation of fatty acid oxidation [GO:0046320]; regulation of insulin secretion [GO:0050796]; regulation of lipid storage [GO:0010883]; response to alkaloid [GO:0043279]; response to antibiotic [GO:0046677]; response to ethanol [GO:0045471]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to tetrachloromethane [GO:1904772]; response to xenobiotic stimulus [GO:0009410]; triglyceride metabolic process [GO:0006641] GO:0001676; GO:0004095; GO:0005739; GO:0005741; GO:0005743; GO:0006006; GO:0006631; GO:0006635; GO:0006641; GO:0009410; GO:0009437; GO:0010876; GO:0010883; GO:0014070; GO:0016020; GO:0030855; GO:0031667; GO:0032000; GO:0042755; GO:0042802; GO:0043231; GO:0043279; GO:0045471; GO:0046320; GO:0046677; GO:0050796; GO:0071398; GO:0097421; GO:1904772; GO:1990698 21546 FUN_001161 522 329 246 459 372 NA NA NA NA NA NA NA 21547 FUN_001162 955 1634 328 554 324 NA NA NA NA NA NA NA 21548 FUN_001163 812 402 407 567 387 NA NA NA NA NA NA NA 21549 FUN_001164 78 55 48 87 62 NA NA NA NA NA NA NA 21550 FUN_001165 316 129 79 136 318 NA NA NA NA NA NA NA 21551 FUN_001166 264 111 119 203 195 ntLink_6:9283402-9288227 Q6ZSS7 1.15e-24 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 21552 FUN_001167 3388 2448 1238 2823 2455 NA NA NA NA NA NA NA 21553 FUN_000417 56 23 0 31 27 NA NA NA NA NA NA NA 21554 FUN_000416 25 9 0 8 42 NA NA NA NA NA NA NA 21555 FUN_000415 14 0 15 0 20 NA NA NA NA NA NA NA 21556 FUN_035818 1540 615 724 728 441 NA NA NA NA NA NA NA 21557 FUN_000413 1357 2868 1033 2779 1953 NA NA NA NA NA NA NA 21558 FUN_000412 229 196 260 288 332 NA NA NA NA NA NA NA 21559 FUN_000411 5983 12312 6104 10840 3969 NA NA NA NA NA NA NA 21560 FUN_000410 2272 2337 1722 1995 2916 NA NA NA NA NA NA NA 21561 FUN_035813 294 146 140 395 292 NA NA NA NA NA NA NA 21562 FUN_035812 438 290 194 373 441 NA NA NA NA NA NA NA 21563 FUN_035811 115 40 80 95 123 NA NA NA NA NA NA NA 21564 FUN_035810 462 245 283 436 312 ptg000025l:12020242-12027798 Q9NYQ7 9.4e-119 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 21565 FUN_035810 462 245 283 436 312 ptg000025l:12020242-12027798 Q9NYQ7 1.67e-96 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 21566 FUN_035810 462 245 283 436 312 ptg000025l:12020242-12027798 Q9NYQ7 3.29e-77 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 21567 FUN_035810 462 245 283 436 312 ptg000025l:12020242-12027798 Q9NYQ7 2.64e-61 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 21568 FUN_035810 462 245 283 436 312 ptg000025l:12020242-12027798 Q9NYQ7 2.42e-52 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 21569 FUN_035810 462 245 283 436 312 ptg000025l:12020242-12027798 Q9NYQ7 3.21e-35 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 21570 FUN_035817 1057 555 499 864 648 ptg000025l:12066607-12074721 P21328 2.99e-32 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 21571 FUN_035816 841 296 267 330 349 NA NA NA NA NA NA NA 21572 FUN_000419 239 66 192 327 151 ntLink_6:2737790-2749013 Q8LHH9 3.09e-57 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 21573 FUN_000419 239 66 192 327 151 ntLink_6:2737790-2749013 Q8LHH9 3.09e-57 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 21574 FUN_000419 239 66 192 327 151 ntLink_6:2737790-2749013 Q8LHH9 3.08e-21 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 21575 FUN_035814 8 4 1 4 201 NA NA NA NA NA NA NA 21576 FUN_016042 264 201 79 225 249 ptg000010l:998641-1001405 Q5R7E5 4.84e-78 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0004719; GO:0005737; GO:0016020 21577 FUN_040923 2122 1552 1551 2720 2071 ptg000033l:4057-48741 Q80W93 1.38e-45 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 21578 FUN_040923 2122 1552 1551 2720 2071 ptg000033l:4057-48741 Q80W93 1.48e-22 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 21579 FUN_040923 2122 1552 1551 2720 2071 ptg000033l:4057-48741 Q80W93 1.15e-21 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 21580 FUN_040923 2122 1552 1551 2720 2071 ptg000033l:4057-48741 Q80W93 4.72e-21 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 21581 FUN_040922 4 13 5 2 7 NA NA NA NA NA NA NA 21582 FUN_040921 509 635 343 565 773 NA NA NA NA NA NA NA 21583 FUN_040920 11 0 23 1 15 NA NA NA NA NA NA NA 21584 FUN_016040 4429 4676 2736 3336 2547 NA NA NA NA NA NA NA 21585 FUN_012559 0 0 0 0 18 NA NA NA NA NA NA NA 21586 FUN_012558 2383 1848 1016 1739 1833 NA NA NA NA NA NA NA 21587 FUN_012555 4857 3961 1999 3255 2646 NA NA NA NA NA NA NA 21588 FUN_012554 696 204 293 374 592 NA NA NA NA NA NA NA 21589 FUN_012557 2476 2176 896 1165 912 NA NA NA NA NA NA NA 21590 FUN_012556 437 673 422 656 400 NA NA NA NA NA NA NA 21591 FUN_012550 633 436 247 591 884 ptg000008l:9809185-9811631 Q8VCE1 8.15e-24 DnaJ homolog subfamily C member 28 Mus musculus (Mouse) Golgi organization [GO:0007030]; Golgi vesicle prefusion complex stabilization [GO:0048213]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0006890; GO:0007030; GO:0017119; GO:0048213 21592 FUN_012553 258 163 126 381 364 ptg000008l:9830862-9831951 Q9Y5Y3 6.39e-83 Probable G-protein coupled receptor 45 (PSP24-1) (PSP24-alpha) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186 21593 FUN_012552 698 346 418 368 466 NA NA NA NA NA NA NA 21594 FUN_016249 246 0 8 438 633 NA NA NA NA NA NA NA 21595 FUN_016248 139 38 1 261 211 NA NA NA NA NA NA NA 21596 FUN_016245 274 102 11 517 547 NA NA NA NA NA NA NA 21597 FUN_016244 8 2 0 44 17 NA NA NA NA NA NA NA 21598 FUN_016247 163 26 0 369 416 NA NA NA NA NA NA NA 21599 FUN_016246 353 109 9 554 933 NA NA NA NA NA NA NA 21600 FUN_016241 71 10 17 127 37 NA NA NA NA NA NA NA 21601 FUN_016243 938 808 287 739 1187 NA NA NA NA NA NA NA 21602 FUN_016242 275 317 92 124 251 NA NA NA NA NA NA NA 21603 FUN_028079 1610 1571 847 1716 1396 ptg000021l:15550718-15558690 Q06546 3.87e-36 GA-binding protein alpha chain (GABP subunit alpha) (Nuclear respiratory factor 2 subunit alpha) (Transcription factor E4TF1-60) Homo sapiens (Human) blastocyst formation [GO:0001825]; cell differentiation [GO:0030154]; cellular response to dopamine [GO:1903351]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0001825; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010628; GO:0030154; GO:0045653; GO:0045944; GO:1903351; GO:1990837 21604 FUN_028078 91002 58100 46636 81871 54104 ptg000021l:15545744-15547014 P29773 3.52e-37 Protein C-ets-2 Lytechinus variegatus (Green sea urchin) (Echinus variegatus) regulation of transcription by RNA polymerase II [GO:0006357] GO:0003700; GO:0005634; GO:0006357; GO:0043565 21605 FUN_028073 410 409 123 181 173 NA NA NA NA NA NA NA 21606 FUN_028072 45 41 84 79 115 NA NA NA NA NA NA NA 21607 FUN_028070 26 498 165 692 577 NA NA NA NA NA NA NA 21608 FUN_028077 9695 6034 5086 9364 5972 NA NA NA NA NA NA NA 21609 FUN_028076 8357 6362 4247 7769 4160 NA NA NA NA NA NA NA 21610 FUN_028075 19362 11006 12610 15071 9452 NA NA NA NA NA NA NA 21611 FUN_028074 105 185 112 42 40 NA NA NA NA NA NA NA 21612 FUN_036892 1480 1112 820 1405 1335 ptg000026l:3176212-3178336 Q2M1K5 6.59e-52 PC-esterase domain-containing protein 1B (Protein FAM113B) Rattus norvegicus (Rat) NA NA 21613 FUN_036893 1509 676 384 751 366 NA NA NA NA NA NA NA 21614 FUN_036890 33 134 44 28 0 NA NA NA NA NA NA NA 21615 FUN_036891 26 23 22 8 19 NA NA NA NA NA NA NA 21616 FUN_036896 1030 545 499 614 717 NA NA NA NA NA NA NA 21617 FUN_036897 3171 1439 787 1653 1329 NA NA NA NA NA NA NA 21618 FUN_036894 1152 815 444 689 479 NA NA NA NA NA NA NA 21619 FUN_036895 485 342 176 244 142 NA NA NA NA NA NA NA 21620 FUN_036898 5363 2933 2118 4375 2757 ptg000026l:3210338-3223736 P33198 5.69e-24 Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) Sus scrofa (Pig) 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004450; GO:0005739; GO:0006097; GO:0006099; GO:0006102; GO:0006103; GO:0006739; GO:0051287 21621 FUN_036899 26846 17627 5663 13562 3840 NA NA NA NA NA NA NA 21622 FUN_039778 47792 57429 30250 43469 20932 NA NA NA NA NA NA NA 21623 FUN_042789 190 392 378 371 1054 NA NA NA NA NA NA NA 21624 FUN_042788 22 16 40 7 276 NA NA NA NA NA NA NA 21625 FUN_042781 123 255 213 231 620 NA NA NA NA NA NA NA 21626 FUN_042780 6 6 18 6 137 NA NA NA NA NA NA NA 21627 FUN_042783 4 0 16 2 101 NA NA NA NA NA NA NA 21628 FUN_042785 60 140 138 146 369 NA NA NA NA NA NA NA 21629 FUN_042784 2 0 5 0 21 NA NA NA NA NA NA NA 21630 FUN_042786 3 0 11 1 88 NA NA NA NA NA NA NA 21631 FUN_041323 8 5 14 26 28 NA NA NA NA NA NA NA 21632 FUN_010957 25506 20623 9179 17318 3248 NA NA NA NA NA NA NA 21633 FUN_043783 14 23 38 45 56 NA NA NA NA NA NA NA 21634 FUN_010955 253 303 114 471 401 NA NA NA NA NA NA NA 21635 FUN_043786 0 11 0 0 0 NA NA NA NA NA NA NA 21636 FUN_010952 1111 417 183 594 444 NA NA NA NA NA NA NA 21637 FUN_010951 18 0 11 96 19 NA NA NA NA NA NA NA 21638 FUN_010950 1087 721 675 1473 948 ptg000007l:4708048-4771338 Q6IVV8 1.25e-34 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 21639 FUN_043789 0 0 11 0 0 NA NA NA NA NA NA NA 21640 FUN_010959 3888 5039 3312 3015 3218 NA NA NA NA NA NA NA 21641 FUN_010958 56 140 49 53 99 NA NA NA NA NA NA NA 21642 FUN_042436 0 0 22 0 65 NA NA NA NA NA NA NA 21643 FUN_042435 16 2 131 12 287 NA NA NA NA NA NA NA 21644 FUN_042434 22 0 40 0 31 NA NA NA NA NA NA NA 21645 FUN_042439 8 0 3 1 32 NA NA NA NA NA NA NA 21646 FUN_042438 0 0 19 0 0 NA NA NA NA NA NA NA 21647 FUN_010633 597 402 313 502 547 NA NA NA NA NA NA NA 21648 FUN_009159 119 2 0 0 30 NA NA NA NA NA NA NA 21649 FUN_022738 57 11 24 19 27 ptg000016l:12701461-12702347 P25291 1.07e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 21650 FUN_022739 58 15 28 18 22 ptg000016l:12702580-12703463 P25291 1.23e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 21651 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21652 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 1.55e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21653 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 5.47e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21654 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 1.89e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21655 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 3.86e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21656 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 3.52e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21657 FUN_009155 155 198 55 56 92 ptg000004l:3324249-3329753 Q96AY4 6.87e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21658 FUN_009154 22 32 67 17 146 NA NA NA NA NA NA NA 21659 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 3.08e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21660 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 2.24e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21661 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 1.11e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21662 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 2.73e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21663 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 2.23e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21664 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 7.27e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21665 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 7.36e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21666 FUN_009157 115 79 13 129 127 ptg000004l:3362038-3372070 Q96AY4 1.84e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21667 FUN_022732 66 12 28 20 21 ptg000016l:12694763-12695646 P25291 1.23e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 21668 FUN_022733 51 13 27 18 25 ptg000016l:12695878-12696761 P25291 1.05e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 21669 FUN_022730 63 12 33 21 37 ptg000016l:12690292-12690772 P25291 3.24e-29 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 21670 FUN_009152 382 324 28 309 367 ptg000004l:3272606-3282311 Q96AY4 7.41e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21671 FUN_009152 382 324 28 309 367 ptg000004l:3272606-3282311 Q96AY4 1.23e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21672 FUN_009152 382 324 28 309 367 ptg000004l:3272606-3282311 Q96AY4 1.07e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21673 FUN_009152 382 324 28 309 367 ptg000004l:3272606-3282311 Q96AY4 2.83e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21674 FUN_029851 9 0 0 0 0 NA NA NA NA NA NA NA 21675 FUN_029856 5 43 0 5 0 NA NA NA NA NA NA NA 21676 FUN_029857 0 37 21 0 13 NA NA NA NA NA NA NA 21677 FUN_040493 2344 1739 1422 2296 1584 NA NA NA NA NA NA NA 21678 FUN_022081 0 7 0 0 31 NA NA NA NA NA NA NA 21679 FUN_022082 0 0 50 0 115 NA NA NA NA NA NA NA 21680 FUN_022083 23 0 0 0 19 NA NA NA NA NA NA NA 21681 FUN_040495 64 2 119 174 42 ptg000031l:9362149-9364618 Q5DU56 6.78e-29 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21682 FUN_040495 64 2 119 174 42 ptg000031l:9362149-9364618 Q5DU56 5.46e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21683 FUN_022087 0 0 0 0 23 NA NA NA NA NA NA NA 21684 FUN_022088 935 818 499 538 686 NA NA NA NA NA NA NA 21685 FUN_022089 0 0 0 0 100 NA NA NA NA NA NA NA 21686 FUN_040499 1042 155 22 53 196 ptg000031l:9405367-9418488 Q7RTR2 3.46e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21687 FUN_040499 1042 155 22 53 196 ptg000031l:9405367-9418488 Q7RTR2 3.38e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21688 FUN_040499 1042 155 22 53 196 ptg000031l:9405367-9418488 Q7RTR2 1.21e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21689 FUN_040498 88 26 18 65 38 NA NA NA NA NA NA NA 21690 FUN_039772 1 0 8 2 112 NA NA NA NA NA NA NA 21691 FUN_040145 1062 2753 1946 4345 12259 NA NA NA NA NA NA NA 21692 FUN_040144 511 43 8 35 146 NA NA NA NA NA NA NA 21693 FUN_040147 53 28 27 13 11 NA NA NA NA NA NA NA 21694 FUN_040146 633 425 794 1688 1941 NA NA NA NA NA NA NA 21695 FUN_040141 206 83 0 0 13 NA NA NA NA NA NA NA 21696 FUN_040140 1176 684 533 818 679 NA NA NA NA NA NA NA 21697 FUN_040143 96 0 13 26 78 NA NA NA NA NA NA NA 21698 FUN_040142 1893 10 0 0 61 NA NA NA NA NA NA NA 21699 FUN_040149 1028 382 674 1273 1153 NA NA NA NA NA NA NA 21700 FUN_040148 30 5 0 6 0 NA NA NA NA NA NA NA 21701 FUN_015200 0 0 0 48 0 ptg000009l:7415263-7417394 Q96CG8 3.51e-32 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 21702 FUN_015201 217 13 83 431 180 ptg000009l:7425151-7426452 Q96CG8 1.94e-33 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 21703 FUN_015202 6 0 0 0 0 ptg000009l:7430629-7442056 Q96CG8 8.1e-32 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 21704 FUN_015203 8448 30 1815 79 64 ptg000009l:7450232-7450889 Q96CG8 1.82e-32 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 21705 FUN_015204 13 0 0 0 0 NA NA NA NA NA NA NA 21706 FUN_015205 25 0 0 0 0 NA NA NA NA NA NA NA 21707 FUN_015206 26 0 24 0 10 NA NA NA NA NA NA NA 21708 FUN_015207 36 0 0 0 35 NA NA NA NA NA NA NA 21709 FUN_015208 32 0 0 0 6 NA NA NA NA NA NA NA 21710 FUN_015209 106 0 16 0 65 NA NA NA NA NA NA NA 21711 FUN_032409 18 10 8 9 32 NA NA NA NA NA NA NA 21712 FUN_024365 562 343 506 450 805 NA NA NA NA NA NA NA 21713 FUN_024364 149 107 123 243 105 NA NA NA NA NA NA NA 21714 FUN_024363 316 254 132 662 608 NA NA NA NA NA NA NA 21715 FUN_024362 180 60 30 141 63 NA NA NA NA NA NA NA 21716 FUN_024361 4 26 15 35 35 NA NA NA NA NA NA NA 21717 FUN_024360 374 142 155 309 161 NA NA NA NA NA NA NA 21718 FUN_032401 0 3 24 8 91 NA NA NA NA NA NA NA 21719 FUN_032400 0 0 17 27 7 ptg000023l:31566751-31569458 Q29RU2 2.47e-24 Oncoprotein-induced transcript 3 protein Bos taurus (Bovine) NA GO:0005509; GO:0005635 21720 FUN_032403 129 32 38 39 43 ptg000023l:31584615-31590028 Q6V0K7 1.16e-21 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 21721 FUN_032402 0 25 11 29 16 NA NA NA NA NA NA NA 21722 FUN_032405 1506 959 851 1521 1559 NA NA NA NA NA NA NA 21723 FUN_032404 136 267 249 976 294 ptg000023l:31592080-31597581 P55259 2.11e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Homo sapiens (Human) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0003823; GO:0005201; GO:0005576; GO:0005615; GO:0005768; GO:0005886; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:0070062; GO:1990266 21724 FUN_024369 243 410 206 245 172 ptg000018l:5489604-5496417 Q03650 3.27e-64 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 21725 FUN_032406 0 64 7 39 0 ptg000023l:31617306-31623820 Q6DIV6 4.84e-47 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 21726 FUN_038447 57 40 105 53 60 NA NA NA NA NA NA NA 21727 FUN_038446 0 0 0 13 0 NA NA NA NA NA NA NA 21728 FUN_038445 32 11 9 0 28 NA NA NA NA NA NA NA 21729 FUN_038444 17 0 8 56 0 NA NA NA NA NA NA NA 21730 FUN_038443 11 61 100 143 30 NA NA NA NA NA NA NA 21731 FUN_038442 26 11 103 24 52 NA NA NA NA NA NA NA 21732 FUN_038441 105 107 30 126 209 NA NA NA NA NA NA NA 21733 FUN_038440 11 19 0 35 44 NA NA NA NA NA NA NA 21734 FUN_038449 7 163 1080 1257 0 NA NA NA NA NA NA NA 21735 FUN_038448 353 810 113 529 387 NA NA NA NA NA NA NA 21736 FUN_028814 480 437 377 321 482 NA NA NA NA NA NA NA 21737 FUN_028817 174 293 180 40 46 NA NA NA NA NA NA NA 21738 FUN_028816 19 44 10 18 93 NA NA NA NA NA NA NA 21739 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21740 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 7.07e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21741 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 1.22e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21742 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 5.16e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21743 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 2e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21744 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 8.77e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21745 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 3.31e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21746 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 3.34e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21747 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 6.2e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21748 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 8.81e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21749 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 2.02e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21750 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 1.12e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21751 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 1.57e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21752 FUN_028811 3709 404 3279 2652 68 ptg000022l:4373830-4470703 Q80XJ3 8.37e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 21753 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 1.14e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21754 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 1.34e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21755 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 1.42e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21756 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 2.17e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21757 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 6.47e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21758 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 2.93e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21759 FUN_028810 56 31 49 43 18 ptg000022l:4359195-4364175 Q96AY4 4.11e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21760 FUN_028813 735 251 513 540 282 NA NA NA NA NA NA NA 21761 FUN_028812 29 19 21 56 164 NA NA NA NA NA NA NA 21762 FUN_028819 1480 889 992 1390 1334 NA NA NA NA NA NA NA 21763 FUN_028818 83 71 68 108 25 NA NA NA NA NA NA NA 21764 FUN_005316 129 143 177 128 217 ntLink_8:33947203-33948623 Q9UNP9 5.05e-154 Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of viral genome replication [GO:0045070]; protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413]; regulation of DNA-templated transcription [GO:0006355] GO:0000398; GO:0000413; GO:0003723; GO:0003729; GO:0003755; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006355; GO:0006457; GO:0008143; GO:0016018; GO:0016607; GO:0034774; GO:0045070; GO:0071007; GO:0071013; GO:1904813 21765 FUN_013981 0 0 0 0 7 NA NA NA NA NA NA NA 21766 FUN_016974 0 12 4 39 35 NA NA NA NA NA NA NA 21767 FUN_003419 0 0 20 0 0 NA NA NA NA NA NA NA 21768 FUN_015977 14718 10714 9219 9662 5844 NA NA NA NA NA NA NA 21769 FUN_015972 35 13 10 77 39 NA NA NA NA NA NA NA 21770 FUN_015973 12 12 0 8 7 NA NA NA NA NA NA NA 21771 FUN_015970 333 102 7 265 431 NA NA NA NA NA NA NA 21772 FUN_015978 21940 19083 12336 25030 23799 NA NA NA NA NA NA NA 21773 FUN_015979 179 657 203 625 480 NA NA NA NA NA NA NA 21774 FUN_039314 55 0 0 24 49 NA NA NA NA NA NA NA 21775 FUN_039315 35 0 0 7 101 NA NA NA NA NA NA NA 21776 FUN_039316 42 17 102 63 11 NA NA NA NA NA NA NA 21777 FUN_039317 2902 2562 3479 2708 1426 NA NA NA NA NA NA NA 21778 FUN_039310 0 9 1 27 15 NA NA NA NA NA NA NA 21779 FUN_039311 0 9 1 0 3 NA NA NA NA NA NA NA 21780 FUN_039312 36 61 0 66 18 NA NA NA NA NA NA NA 21781 FUN_039313 11 22 0 17 20 NA NA NA NA NA NA NA 21782 FUN_003411 6 0 4 2 52 NA NA NA NA NA NA NA 21783 FUN_039319 171 169 141 190 206 NA NA NA NA NA NA NA 21784 FUN_025781 2674 2535 1655 3316 3642 NA NA NA NA NA NA NA 21785 FUN_017196 92 2 28 14 148 NA NA NA NA NA NA NA 21786 FUN_027046 4 2 0 10 0 NA NA NA NA NA NA NA 21787 FUN_017194 0 0 0 0 23 NA NA NA NA NA NA NA 21788 FUN_027044 0 0 0 0 19 NA NA NA NA NA NA NA 21789 FUN_017624 8 0 0 0 3 NA NA NA NA NA NA NA 21790 FUN_017228 7 14 1 24 19 NA NA NA NA NA NA NA 21791 FUN_012618 31 1 5 0 87 NA NA NA NA NA NA NA 21792 FUN_012619 6 0 0 0 0 NA NA NA NA NA NA NA 21793 FUN_012610 2772 1973 1001 1391 1113 NA NA NA NA NA NA NA 21794 FUN_012611 3353 2883 1700 2255 1714 NA NA NA NA NA NA NA 21795 FUN_017224 0 0 0 0 10 NA NA NA NA NA NA NA 21796 FUN_012617 0 0 0 0 7 NA NA NA NA NA NA NA 21797 FUN_012614 0 0 0 0 26 NA NA NA NA NA NA NA 21798 FUN_012615 5 16 0 0 0 NA NA NA NA NA NA NA 21799 FUN_018647 0 8 0 0 0 NA NA NA NA NA NA NA 21800 FUN_038942 0 0 6 0 25 NA NA NA NA NA NA NA 21801 FUN_038940 202 119 127 108 188 NA NA NA NA NA NA NA 21802 FUN_038941 0 15 2 0 0 NA NA NA NA NA NA NA 21803 FUN_038946 19 0 0 0 3 NA NA NA NA NA NA NA 21804 FUN_038944 5 0 7 0 19 NA NA NA NA NA NA NA 21805 FUN_038949 26 16 0 0 44 NA NA NA NA NA NA NA 21806 FUN_041421 8 30 62 15 93 NA NA NA NA NA NA NA 21807 FUN_027955 8 14 17 0 0 NA NA NA NA NA NA NA 21808 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 3.53e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21809 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 6.17e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21810 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 2.36e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21811 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 1.98e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21812 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 3.64e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21813 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 1.13e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21814 FUN_027954 816 1017 829 1664 1858 ptg000021l:13771598-13778639 Q96AY4 3.61e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21815 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21816 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21817 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21818 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21819 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 2.97e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21820 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 9.76e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21821 FUN_027957 1351 1369 1187 2327 2800 ptg000021l:13816780-13826638 Q96AY4 1.53e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21822 FUN_027956 0 16 2 1 25 NA NA NA NA NA NA NA 21823 FUN_027951 55 35 37 17 201 NA NA NA NA NA NA NA 21824 FUN_027950 213 397 160 295 793 ptg000021l:13725066-13726137 Q58EK3 2.61e-67 PI-PLC X domain-containing protein 3 Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042]; signal transduction [GO:0007165] GO:0007165; GO:0008081; GO:0016042; GO:0045202 21825 FUN_027953 452 661 251 509 441 NA NA NA NA NA NA NA 21826 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 6.05e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21827 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 8.25e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21828 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 1.22e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21829 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 2.1e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21830 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 2.38e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21831 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 8.16e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21832 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 9.46e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21833 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 2.99e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21834 FUN_027952 962 1459 1012 2250 2564 ptg000021l:13740552-13747234 Q96AY4 1.44e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21835 FUN_027959 72 86 58 0 97 NA NA NA NA NA NA NA 21836 FUN_027958 1060 1550 1098 2404 3295 ptg000021l:13856279-13863402 Q96AY4 7.77e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21837 FUN_027958 1060 1550 1098 2404 3295 ptg000021l:13856279-13863402 Q96AY4 6.47e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21838 FUN_027958 1060 1550 1098 2404 3295 ptg000021l:13856279-13863402 Q96AY4 2.43e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21839 FUN_027958 1060 1550 1098 2404 3295 ptg000021l:13856279-13863402 Q96AY4 3.51e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21840 FUN_027958 1060 1550 1098 2404 3295 ptg000021l:13856279-13863402 Q96AY4 1.53e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21841 FUN_014759 286 347 136 282 485 NA NA NA NA NA NA NA 21842 FUN_014758 258 25 156 148 354 NA NA NA NA NA NA NA 21843 FUN_014751 1560 1085 721 1769 1182 NA NA NA NA NA NA NA 21844 FUN_014753 1179 962 736 1015 830 ptg000009l:2788759-2800634 Q9W602 7.16e-27 FACT complex subunit SSRP1 (DNA unwinding factor 87 kDa subunit) (DUF87) (Facilitates chromatin transcription complex subunit ssrp1) (Structure-specific recognition protein 1) Xenopus laevis (African clawed frog) cellular component organization [GO:0016043]; DNA repair [GO:0006281]; DNA replication [GO:0006260] GO:0003677; GO:0005694; GO:0005730; GO:0006260; GO:0006281; GO:0016043 21845 FUN_014752 363 258 185 486 471 NA NA NA NA NA NA NA 21846 FUN_014755 2222 2464 1702 1614 948 NA NA NA NA NA NA NA 21847 FUN_014754 5629 6227 4496 4837 4302 NA NA NA NA NA NA NA 21848 FUN_014757 2599 2893 1845 2335 1536 ptg000009l:2817186-2820856 Q8K274 3.02e-21 Ketosamine-3-kinase (EC 2.7.1.172) (Fructosamine-3-kinase-related protein) (FN3K-RP) (FN3K-related protein) (Protein-psicosamine 3-kinase FN3KRP) (EC 2.7.1.-) Mus musculus (Mouse) phosphorylation [GO:0016310] GO:0005524; GO:0016301; GO:0016310; GO:0102193 21849 FUN_014756 1926 1504 964 1566 1050 NA NA NA NA NA NA NA 21850 FUN_026184 440 5 68 211 140 NA NA NA NA NA NA NA 21851 FUN_006507 90 0 48 59 0 NA NA NA NA NA NA NA 21852 FUN_041422 32 59 27 18 131 NA NA NA NA NA NA NA 21853 FUN_026995 11 33 21 1 51 NA NA NA NA NA NA NA 21854 FUN_023289 0 0 0 8 24 NA NA NA NA NA NA NA 21855 FUN_025250 211 63 75 258 164 NA NA NA NA NA NA NA 21856 FUN_009218 0 0 19 0 0 NA NA NA NA NA NA NA 21857 FUN_009219 43 0 0 73 23 NA NA NA NA NA NA NA 21858 FUN_025251 268 144 162 366 328 ptg000019l:424142-434191 A9Z1V5 6.93e-67 von Willebrand factor A domain-containing protein 5B1 Mus musculus (Mouse) NA GO:0005576 21859 FUN_009212 56 60 61 83 8 ptg000004l:4014468-4018431 Q96AY4 8.05e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21860 FUN_009212 56 60 61 83 8 ptg000004l:4014468-4018431 Q96AY4 1.77e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21861 FUN_009212 56 60 61 83 8 ptg000004l:4014468-4018431 Q96AY4 6.42e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21862 FUN_009212 56 60 61 83 8 ptg000004l:4014468-4018431 Q96AY4 8.61e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21863 FUN_009212 56 60 61 83 8 ptg000004l:4014468-4018431 Q96AY4 2.28e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21864 FUN_009213 18 188 60 36 27 ptg000004l:4036386-4051721 Q96AY4 1.31e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21865 FUN_009213 18 188 60 36 27 ptg000004l:4036386-4051721 Q96AY4 1.5e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21866 FUN_009213 18 188 60 36 27 ptg000004l:4036386-4051721 Q96AY4 5.38e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21867 FUN_009213 18 188 60 36 27 ptg000004l:4036386-4051721 Q96AY4 5.07e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21868 FUN_009213 18 188 60 36 27 ptg000004l:4036386-4051721 Q96AY4 3.35e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21869 FUN_009210 0 28 0 13 33 NA NA NA NA NA NA NA 21870 FUN_009216 135 9 132 153 36 ptg000004l:4078065-4083921 Q96AY4 9.09e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21871 FUN_009216 135 9 132 153 36 ptg000004l:4078065-4083921 Q96AY4 8.04e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21872 FUN_009216 135 9 132 153 36 ptg000004l:4078065-4083921 Q96AY4 3.43e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21873 FUN_009216 135 9 132 153 36 ptg000004l:4078065-4083921 Q96AY4 1.31e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21874 FUN_009217 0 10 0 38 0 NA NA NA NA NA NA NA 21875 FUN_009214 0 0 11 234 12 NA NA NA NA NA NA NA 21876 FUN_009215 0 31 0 56 23 NA NA NA NA NA NA NA 21877 FUN_025253 973 984 237 1908 284 NA NA NA NA NA NA NA 21878 FUN_023288 16 905 402 973 863 NA NA NA NA NA NA NA 21879 FUN_022206 555 404 294 356 281 NA NA NA NA NA NA NA 21880 FUN_025255 7 56 8 5 46 NA NA NA NA NA NA NA 21881 FUN_026609 0 0 3 193 0 NA NA NA NA NA NA NA 21882 FUN_022204 552 210 212 251 184 NA NA NA NA NA NA NA 21883 FUN_019266 356 477 71 966 4 NA NA NA NA NA NA NA 21884 FUN_026603 23 31 14 49 39 NA NA NA NA NA NA NA 21885 FUN_019264 15 0 4 10 39 NA NA NA NA NA NA NA 21886 FUN_026604 0 0 0 0 26 NA NA NA NA NA NA NA 21887 FUN_041427 0 0 0 17 0 NA NA NA NA NA NA NA 21888 FUN_025559 52 99 0 48 96 NA NA NA NA NA NA NA 21889 FUN_025558 3138 2502 1537 2198 1579 NA NA NA NA NA NA NA 21890 FUN_025557 64 58 49 125 98 ptg000019l:4407121-4413252 Q4U4D2 4.73e-46 Melanopsin (Opsin-4) Podarcis siculus (Italian wall lizard) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 21891 FUN_025556 2294 2247 2010 3281 2699 NA NA NA NA NA NA NA 21892 FUN_025555 1297 186 807 1486 473 ptg000019l:4271748-4354827 Q7LHG5 1.18e-56 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 21893 FUN_025555 1297 186 807 1486 473 ptg000019l:4271748-4354827 Q7LHG5 1.18e-56 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 21894 FUN_025555 1297 186 807 1486 473 ptg000019l:4271748-4354827 Q7LHG5 1.18e-56 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 21895 FUN_025553 0 7 7 0 46 NA NA NA NA NA NA NA 21896 FUN_025552 132 323 185 249 376 ptg000019l:4253907-4259350 Q5DU56 1.23e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 21897 FUN_025551 78 719 99 157 1275 NA NA NA NA NA NA NA 21898 FUN_025550 0 13 0 0 32 NA NA NA NA NA NA NA 21899 FUN_024609 0 4 10 0 0 NA NA NA NA NA NA NA 21900 FUN_024604 8 0 0 0 28 NA NA NA NA NA NA NA 21901 FUN_024600 38 376 51 108 18 NA NA NA NA NA NA NA 21902 FUN_024603 11 50 0 14 0 NA NA NA NA NA NA NA 21903 FUN_026183 1755 1913 984 1526 1379 NA NA NA NA NA NA NA 21904 FUN_021076 0 0 9 4 13 NA NA NA NA NA NA NA 21905 FUN_021078 21 0 0 4 9 NA NA NA NA NA NA NA 21906 FUN_021079 10 0 7 0 22 NA NA NA NA NA NA NA 21907 FUN_026182 1657 1476 1033 1277 2003 NA NA NA NA NA NA NA 21908 FUN_041428 181 279 82 214 268 NA NA NA NA NA NA NA 21909 FUN_019489 903 532 644 1459 1008 ptg000015l:2820636-2827419 Q96AY4 1.23e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21910 FUN_019489 903 532 644 1459 1008 ptg000015l:2820636-2827419 Q96AY4 1.59e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21911 FUN_019489 903 532 644 1459 1008 ptg000015l:2820636-2827419 Q96AY4 2.54e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21912 FUN_019489 903 532 644 1459 1008 ptg000015l:2820636-2827419 Q96AY4 6.69e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 21913 FUN_019482 0 0 0 0 201 NA NA NA NA NA NA NA 21914 FUN_019483 38 94 6 30 0 NA NA NA NA NA NA NA 21915 FUN_019480 0 0 4 0 8 NA NA NA NA NA NA NA 21916 FUN_019486 28 6 0 0 7 NA NA NA NA NA NA NA 21917 FUN_019484 0 0 11 4 14 NA NA NA NA NA NA NA 21918 FUN_019485 0 0 33 89 67 NA NA NA NA NA NA NA 21919 FUN_041502 129 44 34 79 112 ptg000035l:4437813-4443976 Q62623 1.17e-36 Cell division cycle protein 20 homolog (p55CDC) Rattus norvegicus (Rat) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005829; GO:0007064; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0031145; GO:0031915; GO:0032991; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 21920 FUN_041502 129 44 34 79 112 ptg000035l:4437813-4443976 Q62623 1.17e-36 Cell division cycle protein 20 homolog (p55CDC) Rattus norvegicus (Rat) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005829; GO:0007064; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0031145; GO:0031915; GO:0032991; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 21921 FUN_041502 129 44 34 79 112 ptg000035l:4437813-4443976 Q62623 2.73e-27 Cell division cycle protein 20 homolog (p55CDC) Rattus norvegicus (Rat) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic nuclear division [GO:0040020] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005829; GO:0007064; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0031145; GO:0031915; GO:0032991; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 21922 FUN_023286 0 0 179 0 133 NA NA NA NA NA NA NA 21923 FUN_006299 198 139 137 205 16 NA NA NA NA NA NA NA 21924 FUN_006298 4 0 78 24 50 NA NA NA NA NA NA NA 21925 FUN_006290 6 0 0 0 0 NA NA NA NA NA NA NA 21926 FUN_038168 2015 1459 1116 686 1016 NA NA NA NA NA NA NA 21927 FUN_038169 0 0 0 14 0 NA NA NA NA NA NA NA 21928 FUN_038164 1748 943 1305 1695 1265 NA NA NA NA NA NA NA 21929 FUN_038165 716 730 305 448 567 NA NA NA NA NA NA NA 21930 FUN_038166 1812 897 934 1269 977 ptg000027l:3306966-3311323 Q7ZX03 3.7e-25 Forkhead box protein K2 (FoxK2) (Interleukin enhancer-binding factor 1) (ILF1) (xFoxK1) Xenopus laevis (African clawed frog) canonical glycolysis [GO:0061621]; cellular glucose homeostasis [GO:0001678]; negative regulation of autophagy [GO:0010507]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of glucose metabolic process [GO:0010906]; response to starvation [GO:0042594] GO:0000287; GO:0000976; GO:0001227; GO:0001678; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0006355; GO:0010507; GO:0010906; GO:0042594; GO:0043565; GO:0045892; GO:0045893; GO:0061621 21931 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.88e-83 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21932 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.91e-76 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21933 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 5.34e-61 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21934 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.37e-54 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21935 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.51e-53 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21936 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.51e-53 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21937 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 8.33e-51 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21938 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 8.45e-50 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21939 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 5.47e-47 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21940 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 4.36e-43 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21941 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.31e-37 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21942 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.25e-35 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21943 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.54e-32 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21944 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 4.16e-32 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21945 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 4.58e-31 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21946 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.42e-30 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21947 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 7.74e-30 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21948 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 3.49e-29 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21949 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 5.57e-29 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21950 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.62e-28 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21951 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.07e-28 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21952 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 8.77e-27 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21953 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.31e-26 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21954 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 3.52e-26 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21955 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.12e-25 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21956 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 5.26e-24 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21957 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.02e-22 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21958 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 6.95e-22 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21959 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.09e-21 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21960 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 1.55e-21 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21961 FUN_038167 10864 7242 4760 11947 8448 ptg000027l:3314262-3371233 P23098 2.42e-21 Dynein beta chain, ciliary Tripneustes gratilla (Hawaian sea urchin) (Echinus gratilla) cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0007018; GO:0008569; GO:0030030; GO:0030286; GO:0045505; GO:0051959; GO:0097729 21962 FUN_038160 657 275 225 346 343 NA NA NA NA NA NA NA 21963 FUN_038161 1547 942 729 1070 1232 NA NA NA NA NA NA NA 21964 FUN_038162 455 370 181 231 299 NA NA NA NA NA NA NA 21965 FUN_038163 2425 1194 763 1666 1166 NA NA NA NA NA NA NA 21966 FUN_012408 0 11 9 0 0 NA NA NA NA NA NA NA 21967 FUN_006428 2432 1460 1354 1050 1176 ptg000001l:12365811-12366426 Q99P75 4.17e-73 Ras-related protein Rab-9A Rattus norvegicus (Rat) negative regulation by host of symbiont catalytic activity [GO:0052403]; positive regulation of exocytosis [GO:0045921]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; regulation of protein localization [GO:0032880]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0003924; GO:0005525; GO:0005764; GO:0005770; GO:0005789; GO:0005829; GO:0005886; GO:0015031; GO:0019003; GO:0030659; GO:0030670; GO:0032482; GO:0032880; GO:0042147; GO:0042470; GO:0042802; GO:0045335; GO:0045921; GO:0052403 21968 FUN_041501 707 249 245 347 310 ptg000035l:4417690-4431550 Q60803 7.1e-32 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 21969 FUN_035691 145 49 61 210 110 ptg000025l:10686818-10693155 P0CT39 2.03e-63 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 21970 FUN_035690 80 51 230 12 337 ptg000025l:10679164-10682087 Q96CG8 2.17e-21 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 21971 FUN_021928 1961 1102 1448 1121 725 NA NA NA NA NA NA NA 21972 FUN_035692 545 369 264 275 376 NA NA NA NA NA NA NA 21973 FUN_035695 974 954 776 1145 1158 NA NA NA NA NA NA NA 21974 FUN_035694 936 738 670 862 715 NA NA NA NA NA NA NA 21975 FUN_035697 2884 1748 1104 1945 1913 NA NA NA NA NA NA NA 21976 FUN_035696 2408 2147 1389 1883 2044 NA NA NA NA NA NA NA 21977 FUN_021922 1743 2053 846 1721 1939 NA NA NA NA NA NA NA 21978 FUN_021923 98 216 68 84 90 ptg000016l:3421881-3424768 Q28BZ2 4.05e-36 Adenosine 5'-monophosphoramidase HINT3 (EC 3.9.1.-) (Histidine triad nucleotide-binding protein 3) (HINT-3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0000166; GO:0005634; GO:0005737; GO:0043530 21979 FUN_021920 0 0 0 0 22 NA NA NA NA NA NA NA 21980 FUN_021926 310 278 187 226 232 ptg000016l:3444228-3448040 Q5ZI11 2.83e-34 Leucine-rich repeat-containing protein 45 Gallus gallus (Chicken) NA GO:0005737; GO:0005813 21981 FUN_021927 2361 1787 936 1387 736 NA NA NA NA NA NA NA 21982 FUN_021924 13 15 23 68 23 NA NA NA NA NA NA NA 21983 FUN_021925 634 769 357 658 303 NA NA NA NA NA NA NA 21984 FUN_006429 6026 3588 973 2810 2049 NA NA NA NA NA NA NA 21985 FUN_020031 0 49 0 0 0 NA NA NA NA NA NA NA 21986 FUN_020030 0 0 0 0 15 NA NA NA NA NA NA NA 21987 FUN_028030 33567 27025 14772 29337 13035 NA NA NA NA NA NA NA 21988 FUN_001748 76 149 90 82 0 NA NA NA NA NA NA NA 21989 FUN_001749 1480 1205 695 1127 748 NA NA NA NA NA NA NA 21990 FUN_001740 686 387 1046 1097 325 NA NA NA NA NA NA NA 21991 FUN_001741 914 803 416 891 781 NA NA NA NA NA NA NA 21992 FUN_001742 267 222 60 161 28 NA NA NA NA NA NA NA 21993 FUN_001743 480 971 376 327 173 ntLink_6:15498414-15544466 P20825 8.84e-46 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 21994 FUN_001743 480 971 376 327 173 ntLink_6:15498414-15544466 P20825 8.84e-46 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 21995 FUN_001744 134 28 7 7 288 NA NA NA NA NA NA NA 21996 FUN_001745 184 80 16 143 207 NA NA NA NA NA NA NA 21997 FUN_001746 1383 1494 798 907 315 NA NA NA NA NA NA NA 21998 FUN_001747 1193 656 577 681 1156 NA NA NA NA NA NA NA 21999 FUN_001962 25 9 21 22 5 NA NA NA NA NA NA NA 22000 FUN_037921 40 172 138 154 214 NA NA NA NA NA NA NA 22001 FUN_037920 1099 708 589 931 739 NA NA NA NA NA NA NA 22002 FUN_037923 4303 3053 2239 4321 3454 NA NA NA NA NA NA NA 22003 FUN_037922 884 809 375 756 426 NA NA NA NA NA NA NA 22004 FUN_037925 751 844 729 1104 706 NA NA NA NA NA NA NA 22005 FUN_037924 1409 932 780 1286 1235 NA NA NA NA NA NA NA 22006 FUN_037927 804 681 479 710 545 NA NA NA NA NA NA NA 22007 FUN_037926 2893 4706 2431 6326 6257 ptg000027l:582911-599726 Q99758 2.56e-58 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Homo sapiens (Human) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; protein metabolic process [GO:0019538]; regulation of lipid biosynthetic process [GO:0046890]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; response to xenobiotic stimulus [GO:0009410]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005615; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0009410; GO:0010875; GO:0015914; GO:0016887; GO:0019538; GO:0030324; GO:0030659; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 22008 FUN_037926 2893 4706 2431 6326 6257 ptg000027l:582911-599726 Q99758 7.69e-40 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Homo sapiens (Human) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; protein metabolic process [GO:0019538]; regulation of lipid biosynthetic process [GO:0046890]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; response to xenobiotic stimulus [GO:0009410]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005615; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0009410; GO:0010875; GO:0015914; GO:0016887; GO:0019538; GO:0030324; GO:0030659; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 22009 FUN_037926 2893 4706 2431 6326 6257 ptg000027l:582911-599726 Q99758 8.23e-38 Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] Homo sapiens (Human) lipid transport [GO:0006869]; lung development [GO:0030324]; organelle assembly [GO:0070925]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylglycerol metabolic process [GO:0046471]; phospholipid homeostasis [GO:0055091]; phospholipid transport [GO:0015914]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of phospholipid efflux [GO:1902995]; positive regulation of phospholipid transport [GO:2001140]; positive regulation of protein homooligomerization [GO:0032464]; protein metabolic process [GO:0019538]; regulation of lipid biosynthetic process [GO:0046890]; regulation of phosphatidylcholine metabolic process [GO:0150172]; response to glucocorticoid [GO:0051384]; response to xenobiotic stimulus [GO:0009410]; surfactant homeostasis [GO:0043129]; xenobiotic export from cell [GO:0046618]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005319; GO:0005524; GO:0005615; GO:0005765; GO:0005770; GO:0005886; GO:0006855; GO:0006869; GO:0008559; GO:0009410; GO:0010875; GO:0015914; GO:0016887; GO:0019538; GO:0030324; GO:0030659; GO:0032464; GO:0032585; GO:0042599; GO:0042626; GO:0042908; GO:0043129; GO:0043231; GO:0046470; GO:0046471; GO:0046618; GO:0046890; GO:0051384; GO:0055091; GO:0070925; GO:0097208; GO:0097232; GO:0097233; GO:0120019; GO:0140345; GO:0150172; GO:1902995; GO:2001140 22010 FUN_037929 902 585 580 542 398 NA NA NA NA NA NA NA 22011 FUN_037928 1732 402 319 892 411 ptg000027l:611062-613812 Q96CG8 9.61e-23 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22012 FUN_005241 148 97 75 198 140 NA NA NA NA NA NA NA 22013 FUN_005240 7224 6822 4743 7268 5069 NA NA NA NA NA NA NA 22014 FUN_005243 1774 2632 2792 3924 1585 NA NA NA NA NA NA NA 22015 FUN_005242 953 718 487 1209 694 ntLink_8:33060460-33073043 Q96DM1 1.28e-60 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 22016 FUN_005245 972 904 662 657 499 NA NA NA NA NA NA NA 22017 FUN_005244 2651 1906 2110 4362 3037 ntLink_8:33085115-33118807 Q9Y485 1.06e-107 DmX-like protein 1 (X-like 1 protein) Homo sapiens (Human) vacuolar acidification [GO:0007035] GO:0007035; GO:0043291 22018 FUN_005244 2651 1906 2110 4362 3037 ntLink_8:33085115-33118807 Q9Y485 1.32e-27 DmX-like protein 1 (X-like 1 protein) Homo sapiens (Human) vacuolar acidification [GO:0007035] GO:0007035; GO:0043291 22019 FUN_005247 3188 1645 3839 3561 2885 NA NA NA NA NA NA NA 22020 FUN_005246 164 169 77 160 140 NA NA NA NA NA NA NA 22021 FUN_005249 0 0 0 0 10 ntLink_8:33139098-33141450 Q06725 1.01e-35 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 22022 FUN_005249 0 0 0 0 10 ntLink_8:33139098-33141450 Q06725 1.82e-35 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 22023 FUN_005248 95 28 98 76 131 NA NA NA NA NA NA NA 22024 FUN_037699 1590 1398 511 1147 1182 NA NA NA NA NA NA NA 22025 FUN_037698 1778 1632 971 1771 1655 NA NA NA NA NA NA NA 22026 FUN_037693 62 11 44 22 81 NA NA NA NA NA NA NA 22027 FUN_037692 70 78 11 88 39 ptg000026l:12456109-12458373 Q5XXP2 6.07e-29 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 22028 FUN_037691 5 9 5 13 7 NA NA NA NA NA NA NA 22029 FUN_037690 2239 1603 1922 2675 4243 NA NA NA NA NA NA NA 22030 FUN_037697 324 158 219 362 268 NA NA NA NA NA NA NA 22031 FUN_037696 206 4 149 206 176 ptg000026l:12503843-12505022 Q61212 2.84e-22 Neuropeptide Y receptor type 6 (NPY6-R) (Pancreatic polypeptide receptor 2) (PP2) Mus musculus (Mouse) NA GO:0001601; GO:0004983; GO:0005886; GO:0008188; GO:0042923; GO:0043005 22032 FUN_037695 107 18 70 74 158 ptg000026l:12475782-12496455 Q5XXP2 1.5e-26 Melanopsin (Opsin-4) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) hyaloid vascular plexus regression [GO:1990384]; optokinetic behavior [GO:0007634]; phototransduction [GO:0007602]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511]; visual perception [GO:0007601] GO:0005502; GO:0005886; GO:0007601; GO:0007602; GO:0007634; GO:0008020; GO:0016020; GO:0030424; GO:0030425; GO:0042752; GO:0043204; GO:0048511; GO:1990384 22033 FUN_037694 70 22 25 10 27 NA NA NA NA NA NA NA 22034 FUN_027568 6 0 2 3 0 NA NA NA NA NA NA NA 22035 FUN_027564 0 0 0 0 44 NA NA NA NA NA NA NA 22036 FUN_027560 24 9 0 12 3 NA NA NA NA NA NA NA 22037 FUN_027561 75 35 22 81 97 NA NA NA NA NA NA NA 22038 FUN_027562 3 0 4 20 26 NA NA NA NA NA NA NA 22039 FUN_027563 0 0 11 0 0 NA NA NA NA NA NA NA 22040 FUN_028665 0 0 0 11 0 NA NA NA NA NA NA NA 22041 FUN_033330 0 0 11 11 25 NA NA NA NA NA NA NA 22042 FUN_033331 0 0 32 0 18 NA NA NA NA NA NA NA 22043 FUN_033333 4 0 0 0 18 NA NA NA NA NA NA NA 22044 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 2.88e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22045 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 1.48e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22046 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 2.05e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22047 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 2.18e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22048 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 1.23e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22049 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 3.27e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22050 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 9.37e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22051 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 4.17e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22052 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 5.75e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22053 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 1.94e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22054 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 2.15e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22055 FUN_033336 151 0 70 338 156 ptg000023l:42035049-42042282 Q96AY4 2.29e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22056 FUN_033339 10 0 0 0 0 NA NA NA NA NA NA NA 22057 FUN_010994 16 2 13 36 34 NA NA NA NA NA NA NA 22058 FUN_008387 1021 430 582 646 551 ptg000002l:11042230-11047456 Q54KX5 4.44e-41 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Dictyostelium discoideum (Social amoeba) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005576; GO:0005975; GO:0047402 22059 FUN_008387 1021 430 582 646 551 ptg000002l:11042230-11047456 Q54KX5 4.64e-24 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Dictyostelium discoideum (Social amoeba) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005576; GO:0005975; GO:0047402 22060 FUN_008386 96 56 18 207 212 NA NA NA NA NA NA NA 22061 FUN_008385 381 231 125 755 834 ptg000002l:11034782-11037348 F1NZI4 7.6e-39 Protein-glucosylgalactosylhydroxylysine glucosidase (EC 3.2.1.107) (Acid trehalase-like protein 1) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975] GO:0004553; GO:0005829; GO:0005975; GO:0047402 22062 FUN_043431 620 351 176 426 391 NA NA NA NA NA NA NA 22063 FUN_008384 125 110 20 55 154 NA NA NA NA NA NA NA 22064 FUN_016869 722 324 195 509 304 NA NA NA NA NA NA NA 22065 FUN_016868 2315 1059 1071 1545 1536 ptg000011l:8222488-8243624 Q9QZ05 5.12e-102 eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] GO:0000049; GO:0000077; GO:0001934; GO:0002230; GO:0002250; GO:0002286; GO:0002821; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005829; GO:0005844; GO:0006446; GO:0006468; GO:0007049; GO:0007612; GO:0007616; GO:0009267; GO:0010628; GO:0010998; GO:0017148; GO:0019081; GO:0022626; GO:0030968; GO:0032057; GO:0032792; GO:0034198; GO:0034644; GO:0034976; GO:0036492; GO:0043558; GO:0044828; GO:0045665; GO:0045947; GO:0046777; GO:0051607; GO:0060259; GO:0070417; GO:0071074; GO:0071264; GO:0106310; GO:0140469; GO:1900273; GO:1990138; GO:1990253 22066 FUN_016868 2315 1059 1071 1545 1536 ptg000011l:8222488-8243624 Q9QZ05 5.12e-102 eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] GO:0000049; GO:0000077; GO:0001934; GO:0002230; GO:0002250; GO:0002286; GO:0002821; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005829; GO:0005844; GO:0006446; GO:0006468; GO:0007049; GO:0007612; GO:0007616; GO:0009267; GO:0010628; GO:0010998; GO:0017148; GO:0019081; GO:0022626; GO:0030968; GO:0032057; GO:0032792; GO:0034198; GO:0034644; GO:0034976; GO:0036492; GO:0043558; GO:0044828; GO:0045665; GO:0045947; GO:0046777; GO:0051607; GO:0060259; GO:0070417; GO:0071074; GO:0071264; GO:0106310; GO:0140469; GO:1900273; GO:1990138; GO:1990253 22067 FUN_016868 2315 1059 1071 1545 1536 ptg000011l:8222488-8243624 Q9QZ05 2.3e-21 eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; cell cycle [GO:0007049]; cellular response to amino acid starvation [GO:0034198]; cellular response to cold [GO:0070417]; cellular response to leucine starvation [GO:1990253]; cellular response to starvation [GO:0009267]; cellular response to UV [GO:0034644]; defense response to virus [GO:0051607]; DNA damage checkpoint signaling [GO:0000077]; eiF2alpha phosphorylation in response to endoplasmic reticulum stress [GO:0036492]; endoplasmic reticulum unfolded protein response [GO:0030968]; GCN2-mediated signaling [GO:0140469]; learning [GO:0007612]; long-term memory [GO:0007616]; negative regulation by host of viral genome replication [GO:0044828]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of translation [GO:0017148]; negative regulation of translational initiation [GO:0045947]; negative regulation of translational initiation in response to stress [GO:0032057]; neuron projection extension [GO:1990138]; positive regulation of adaptive immune response [GO:0002821]; positive regulation of defense response to virus by host [GO:0002230]; positive regulation of gene expression [GO:0010628]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translational initiation in response to starvation [GO:0071264]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of feeding behavior [GO:0060259]; regulation of translational initiation [GO:0006446]; regulation of translational initiation by eIF2 alpha phosphorylation [GO:0010998]; regulation of translational initiation in response to stress [GO:0043558]; response to endoplasmic reticulum stress [GO:0034976]; T cell activation involved in immune response [GO:0002286]; viral translation [GO:0019081] GO:0000049; GO:0000077; GO:0001934; GO:0002230; GO:0002250; GO:0002286; GO:0002821; GO:0004672; GO:0004674; GO:0004694; GO:0005524; GO:0005829; GO:0005844; GO:0006446; GO:0006468; GO:0007049; GO:0007612; GO:0007616; GO:0009267; GO:0010628; GO:0010998; GO:0017148; GO:0019081; GO:0022626; GO:0030968; GO:0032057; GO:0032792; GO:0034198; GO:0034644; GO:0034976; GO:0036492; GO:0043558; GO:0044828; GO:0045665; GO:0045947; GO:0046777; GO:0051607; GO:0060259; GO:0070417; GO:0071074; GO:0071264; GO:0106310; GO:0140469; GO:1900273; GO:1990138; GO:1990253 22068 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 1.07e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22069 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 2.91e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22070 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 1.99e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22071 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 2.52e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22072 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 1.84e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22073 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 1.05e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22074 FUN_016865 212 170 110 246 121 ptg000011l:8186187-8190134 Q96AY4 1.43e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22075 FUN_043917 4 2 19 10 108 NA NA NA NA NA NA NA 22076 FUN_016867 302 49 35 36 100 NA NA NA NA NA NA NA 22077 FUN_016866 0 0 0 9 0 NA NA NA NA NA NA NA 22078 FUN_016861 0 0 21 7 336 NA NA NA NA NA NA NA 22079 FUN_016860 0 0 0 0 31 NA NA NA NA NA NA NA 22080 FUN_016863 52 263 40 249 197 ptg000011l:8153066-8157227 Q96AY4 7.05e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22081 FUN_016863 52 263 40 249 197 ptg000011l:8153066-8157227 Q96AY4 9.02e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22082 FUN_016863 52 263 40 249 197 ptg000011l:8153066-8157227 Q96AY4 1.56e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22083 FUN_016863 52 263 40 249 197 ptg000011l:8153066-8157227 Q96AY4 1.26e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22084 FUN_016863 52 263 40 249 197 ptg000011l:8153066-8157227 Q96AY4 4.69e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22085 FUN_016863 52 263 40 249 197 ptg000011l:8153066-8157227 Q96AY4 1.8e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22086 FUN_043916 1 1 4 6 12 NA NA NA NA NA NA NA 22087 FUN_004596 0 21 0 63 5 NA NA NA NA NA NA NA 22088 FUN_004597 68 145 30 100 55 NA NA NA NA NA NA NA 22089 FUN_004594 40 16 28 35 35 NA NA NA NA NA NA NA 22090 FUN_004595 374 68 40 224 58 NA NA NA NA NA NA NA 22091 FUN_004592 16 3 25 28 22 NA NA NA NA NA NA NA 22092 FUN_004593 60 36 64 75 44 NA NA NA NA NA NA NA 22093 FUN_004590 1216 837 640 828 745 NA NA NA NA NA NA NA 22094 FUN_004591 94 24 155 37 36 NA NA NA NA NA NA NA 22095 FUN_004598 212 298 211 139 42 NA NA NA NA NA NA NA 22096 FUN_004599 18701 23488 7936 10004 7828 NA NA NA NA NA NA NA 22097 FUN_006576 11 5 4 0 0 ptg000001l:14309999-14311142 Q9EQD2 1.92e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 22098 FUN_006577 94 19 18 23 121 ptg000001l:14315240-14316230 P79218 6.28e-23 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 22099 FUN_006574 0 34 0 4 3 ptg000001l:14281703-14288109 P49217 1.1e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) NA GO:0005886; GO:0008502 22100 FUN_006575 7 0 0 0 2 NA NA NA NA NA NA NA 22101 FUN_006572 2893 1880 1824 1410 734 ptg000001l:14246812-14247853 A7RFT2 1.4e-143 Cell division cycle protein 123 homolog Nematostella vectensis (Starlet sea anemone) cell cycle [GO:0007049]; cell division [GO:0051301] GO:0005737; GO:0007049; GO:0051301 22102 FUN_006573 530 304 64 364 423 ptg000001l:14249364-14256604 P46850 5.53e-29 RNA-splicing ligase RtcB (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; RNA processing [GO:0006396]; RNA repair [GO:0042245]; tRNA processing [GO:0008033] GO:0003909; GO:0005525; GO:0006281; GO:0006396; GO:0006974; GO:0008033; GO:0008452; GO:0030145; GO:0042245 22103 FUN_006570 101 108 42 173 89 NA NA NA NA NA NA NA 22104 FUN_006571 502 279 209 646 327 NA NA NA NA NA NA NA 22105 FUN_006578 1437 1038 594 1356 1256 NA NA NA NA NA NA NA 22106 FUN_000157 2 0 5 0 17 ntLink_4:256092-256855 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 22107 FUN_004628 389 95 100 554 437 NA NA NA NA NA NA NA 22108 FUN_004629 63 31 0 36 27 NA NA NA NA NA NA NA 22109 FUN_033596 3 0 5 4 10 NA NA NA NA NA NA NA 22110 FUN_004624 4316 2791 2435 4449 2612 NA NA NA NA NA NA NA 22111 FUN_004625 2364 2202 1435 2324 2764 ntLink_8:25005378-25036244 Q805A1 1.33e-21 Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) Xenopus laevis (African clawed frog) cell cycle [GO:0007049]; cell division [GO:0051301]; cellular senescence [GO:0090398]; double-strand break repair via homologous recombination [GO:0000724]; positive regulation of maintenance of mitotic sister chromatid cohesion [GO:0034184]; telomere maintenance via recombination [GO:0000722] GO:0000722; GO:0000724; GO:0000781; GO:0005524; GO:0005634; GO:0007049; GO:0016605; GO:0016887; GO:0030915; GO:0034184; GO:0051301; GO:0090398 22112 FUN_004627 394 267 172 389 300 NA NA NA NA NA NA NA 22113 FUN_005386 525 203 307 247 159 NA NA NA NA NA NA NA 22114 FUN_034643 0 0 0 0 11 NA NA NA NA NA NA NA 22115 FUN_034645 24 63 16 0 56 NA NA NA NA NA NA NA 22116 FUN_034649 7 0 10 7 0 NA NA NA NA NA NA NA 22117 FUN_041369 1093 1223 801 1727 1741 NA NA NA NA NA NA NA 22118 FUN_041366 4 0 36 26 40 NA NA NA NA NA NA NA 22119 FUN_015554 0 4 11 1 0 NA NA NA NA NA NA NA 22120 FUN_028389 0 23 0 7 0 NA NA NA NA NA NA NA 22121 FUN_028388 0 91 101 9 0 NA NA NA NA NA NA NA 22122 FUN_028384 0 0 76 41 81 NA NA NA NA NA NA NA 22123 FUN_028387 0 34 0 86 0 NA NA NA NA NA NA NA 22124 FUN_028386 0 32 0 84 0 NA NA NA NA NA NA NA 22125 FUN_028381 32 39 231 220 5 NA NA NA NA NA NA NA 22126 FUN_028380 0 181 269 156 13 NA NA NA NA NA NA NA 22127 FUN_028383 20 0 0 0 0 NA NA NA NA NA NA NA 22128 FUN_028382 0 0 0 778 0 NA NA NA NA NA NA NA 22129 FUN_006950 2374 1702 1494 2788 1995 NA NA NA NA NA NA NA 22130 FUN_041950 10064 6836 4374 5499 3779 NA NA NA NA NA NA NA 22131 FUN_041953 2 6 30 11 8 ptg000035l:9285266-9286310 Q6W3F4 1.64e-23 Adenosine receptor A2b Canis lupus familiaris (Dog) (Canis familiaris) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; vasodilation [GO:0042311] GO:0001609; GO:0004930; GO:0005886; GO:0007186; GO:0007189; GO:0042311 22132 FUN_041952 3405 1966 2424 2945 2551 ptg000035l:9271804-9280929 Q5BL81 3.63e-24 Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sodium ion transport [GO:0006814] GO:0006814; GO:0015293; GO:0016020 22133 FUN_041955 471 415 382 568 624 NA NA NA NA NA NA NA 22134 FUN_041954 2208 1457 1196 1445 1360 NA NA NA NA NA NA NA 22135 FUN_041957 65 117 4 32 25 ptg000035l:9307592-9310573 Q498S8 3.06e-22 Frizzled-8 (Fz-8) Rattus norvegicus (Rat) angiogenesis [GO:0001525]; canonical Wnt signaling pathway [GO:0060070]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of protein phosphorylation [GO:0001934]; T cell differentiation in thymus [GO:0033077]; Wnt signaling pathway [GO:0016055] GO:0001525; GO:0001934; GO:0004930; GO:0005102; GO:0005794; GO:0005886; GO:0016020; GO:0016055; GO:0017147; GO:0030165; GO:0031625; GO:0033077; GO:0042813; GO:0043507; GO:0060070; GO:0098992; GO:1990851 22136 FUN_041956 0 0 0 0 7 NA NA NA NA NA NA NA 22137 FUN_041959 10193 8459 3916 4725 4446 NA NA NA NA NA NA NA 22138 FUN_041958 177 191 77 198 135 NA NA NA NA NA NA NA 22139 FUN_002508 12938 314 44 97 95 ntLink_8:2613105-2686349 Q5F4A1 9.85e-47 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0046872 22140 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 6.81e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22141 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 1.27e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22142 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 1.36e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22143 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 1.37e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22144 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 3.06e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22145 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 2.56e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22146 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 3.21e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22147 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 6.06e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22148 FUN_002506 198 29 29 170 8 ntLink_8:2588763-2591886 Q80XJ3 6.55e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22149 FUN_011071 48 32 30 10 86 NA NA NA NA NA NA NA 22150 FUN_011070 3 0 38 0 223 NA NA NA NA NA NA NA 22151 FUN_002503 80 31 14 14 0 NA NA NA NA NA NA NA 22152 FUN_002501 534 392 317 1243 694 NA NA NA NA NA NA NA 22153 FUN_002500 72 53 23 24 49 NA NA NA NA NA NA NA 22154 FUN_035996 0 51 85 54 6 NA NA NA NA NA NA NA 22155 FUN_035997 19 0 6 10 3 NA NA NA NA NA NA NA 22156 FUN_035994 0 0 0 6 0 NA NA NA NA NA NA NA 22157 FUN_035995 0 38 0 0 18 NA NA NA NA NA NA NA 22158 FUN_035992 0 0 9 0 0 NA NA NA NA NA NA NA 22159 FUN_035993 0 0 17 0 0 NA NA NA NA NA NA NA 22160 FUN_035990 23 117 48 75 20 NA NA NA NA NA NA NA 22161 FUN_035991 0 12 7 18 0 NA NA NA NA NA NA NA 22162 FUN_035998 1047 637 468 803 861 NA NA NA NA NA NA NA 22163 FUN_035999 71 63 0 31 11 NA NA NA NA NA NA NA 22164 FUN_025997 324 276 76 213 412 ptg000020l:3056795-3060519 Q7RTR2 4.02e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22165 FUN_043089 1821 1831 864 1059 611 ptg000047l:3972913-3976470 Q9NX01 1.49e-22 Thioredoxin-like protein 4B (Dim1-like protein) Homo sapiens (Human) cell cycle [GO:0007049]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005654; GO:0005681; GO:0005682; GO:0005829; GO:0007049; GO:0046540 22166 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 8.19e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22167 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 8.57e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22168 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 8.15e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22169 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 1.38e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22170 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 2.69e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22171 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 5.77e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22172 FUN_009565 354 9 29 261 187 ptg000004l:8637623-8640304 Q96AY4 6.41e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22173 FUN_043085 1715 1237 1082 1313 1076 NA NA NA NA NA NA NA 22174 FUN_043084 415 333 207 378 425 ptg000047l:3884868-3919501 Q9VJJ7 5.35e-23 Transient receptor potential-gamma protein (TRPgamma) (Transient receptor potential cation channel gamma) Drosophila melanogaster (Fruit fly) adult walking behavior [GO:0007628]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cation transport [GO:0006812]; detection of light stimulus involved in visual perception [GO:0050908]; neuromuscular process controlling posture [GO:0050884]; regulation of cytosolic calcium ion concentration [GO:0051480]; response to light stimulus [GO:0009416] GO:0005261; GO:0005262; GO:0005886; GO:0006812; GO:0006816; GO:0007628; GO:0008381; GO:0009416; GO:0015279; GO:0016028; GO:0034703; GO:0043025; GO:0050884; GO:0050908; GO:0051480; GO:0070588; GO:0070679; GO:1990635 22175 FUN_043087 912 191 306 802 744 NA NA NA NA NA NA NA 22176 FUN_043086 242 116 167 165 298 ptg000047l:3937427-3940634 Q6GNV7 2.48e-34 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 22177 FUN_043081 931 680 379 1096 917 NA NA NA NA NA NA NA 22178 FUN_043080 53 33 46 101 69 ptg000047l:3806892-3812799 Q96AY4 2.4e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22179 FUN_043080 53 33 46 101 69 ptg000047l:3806892-3812799 Q96AY4 5.75e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22180 FUN_043080 53 33 46 101 69 ptg000047l:3806892-3812799 Q96AY4 7.75e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22181 FUN_043080 53 33 46 101 69 ptg000047l:3806892-3812799 Q96AY4 1.17e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22182 FUN_043080 53 33 46 101 69 ptg000047l:3806892-3812799 Q96AY4 1.71e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22183 FUN_043080 53 33 46 101 69 ptg000047l:3806892-3812799 Q96AY4 6.51e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22184 FUN_043083 375 219 183 441 300 ptg000047l:3844342-3881405 P0CT39 1.21e-83 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 22185 FUN_043082 2013 1912 684 1370 1181 NA NA NA NA NA NA NA 22186 FUN_029261 857 923 406 736 596 NA NA NA NA NA NA NA 22187 FUN_029262 903 866 542 1042 1373 ptg000022l:9709210-9715522 Q6DG03 8.53e-30 Cyclin-D-binding Myb-like transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000976; GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007049 22188 FUN_000620 666 181 306 450 239 ntLink_6:5161038-5166932 O95427 1.09e-96 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016254; GO:0051377 22189 FUN_000620 666 181 306 450 239 ntLink_6:5161038-5166932 O95427 3.45e-45 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016254; GO:0051377 22190 FUN_000620 666 181 306 450 239 ntLink_6:5161038-5166932 O95427 6.24e-39 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016254; GO:0051377 22191 FUN_000620 666 181 306 450 239 ntLink_6:5161038-5166932 O95427 3.05e-36 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016020; GO:0016254; GO:0051377 22192 FUN_029264 234 202 121 247 271 NA NA NA NA NA NA NA 22193 FUN_029267 236 101 104 186 134 NA NA NA NA NA NA NA 22194 FUN_029266 790 353 484 824 611 NA NA NA NA NA NA NA 22195 FUN_029269 13507 9476 8277 15149 10846 ptg000022l:9770382-9776590 Q22235 2.72e-52 Endoplasmin homolog Caenorhabditis elegans protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0005788; GO:0006457; GO:0016887; GO:0030433; GO:0048471; GO:0051082; GO:0140662 22196 FUN_029269 13507 9476 8277 15149 10846 ptg000022l:9770382-9776590 Q22235 2.72e-52 Endoplasmin homolog Caenorhabditis elegans protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0005788; GO:0006457; GO:0016887; GO:0030433; GO:0048471; GO:0051082; GO:0140662 22197 FUN_029269 13507 9476 8277 15149 10846 ptg000022l:9770382-9776590 Q22235 4.9e-41 Endoplasmin homolog Caenorhabditis elegans protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0005788; GO:0006457; GO:0016887; GO:0030433; GO:0048471; GO:0051082; GO:0140662 22198 FUN_029269 13507 9476 8277 15149 10846 ptg000022l:9770382-9776590 Q22235 1.27e-27 Endoplasmin homolog Caenorhabditis elegans protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0005788; GO:0006457; GO:0016887; GO:0030433; GO:0048471; GO:0051082; GO:0140662 22199 FUN_029269 13507 9476 8277 15149 10846 ptg000022l:9770382-9776590 Q22235 1.31e-24 Endoplasmin homolog Caenorhabditis elegans protein folding [GO:0006457]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0005524; GO:0005783; GO:0005788; GO:0006457; GO:0016887; GO:0030433; GO:0048471; GO:0051082; GO:0140662 22200 FUN_029268 731 548 363 606 518 ptg000022l:9766177-9768043 Q9DBW0 2.12e-28 Cytochrome P450 4V2 (Docosahexaenoic acid omega-hydroxylase CYP4V2) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) Mus musculus (Mouse) fatty acid omega-oxidation [GO:0010430] GO:0005506; GO:0005789; GO:0010430; GO:0020037; GO:0102033 22201 FUN_000628 0 62 41 0 3 ntLink_6:5198685-5199123 Q9R1S3 1.56e-44 GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N) Mus musculus (Mouse) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0005829; GO:0005886; GO:0006506; GO:0016780; GO:0051377 22202 FUN_000629 2693 7875 3157 2071 648 ntLink_6:5199177-5201716 P41826 0 Heat shock protein 70 A2 Anopheles albimanus (New world malaria mosquito) NA GO:0005524; GO:0140662 22203 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 3.16e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22204 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 2.87e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22205 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 4.12e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22206 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 1.66e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22207 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 3.86e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22208 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 2.85e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22209 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 1.64e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22210 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 8.05e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22211 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 8.75e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22212 FUN_009561 898 425 202 212 562 ptg000004l:8562772-8573833 Q96AY4 1.04e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22213 FUN_013508 117 235 160 98 68 ptg000008l:23476224-23479465 Q99570 3.53e-45 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22214 FUN_013508 117 235 160 98 68 ptg000008l:23476224-23479465 Q99570 1.64e-21 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22215 FUN_013505 58 91 13 0 179 NA NA NA NA NA NA NA 22216 FUN_013504 0 7 0 0 0 NA NA NA NA NA NA NA 22217 FUN_013507 161 133 132 200 37 ptg000008l:23473412-23474300 P0C0R5 7.43e-43 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22218 FUN_013507 161 133 132 200 37 ptg000008l:23473412-23474300 P0C0R5 7.43e-43 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Rattus norvegicus (Rat) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 22219 FUN_013506 175 59 76 176 24 NA NA NA NA NA NA NA 22220 FUN_013502 1418 830 491 1380 141 ptg000008l:23431269-23442253 Q7RTR2 4.24e-76 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22221 FUN_013502 1418 830 491 1380 141 ptg000008l:23431269-23442253 Q7RTR2 4.73e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22222 FUN_013502 1418 830 491 1380 141 ptg000008l:23431269-23442253 Q7RTR2 5.95e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22223 FUN_013502 1418 830 491 1380 141 ptg000008l:23431269-23442253 Q7RTR2 5.09e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22224 FUN_043629 725 480 400 725 500 ptg000047l:10964101-10970459 B2GUY0 1.63e-42 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Mannosidase alpha class 1B member 1) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; protein alpha-1,2-demannosylation [GO:0036508]; protein glycosylation [GO:0006486]; trimming of terminal mannose on B branch [GO:0036509]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004571; GO:0005509; GO:0005783; GO:0005789; GO:0005975; GO:0006486; GO:0006491; GO:0016020; GO:0030433; GO:0031410; GO:0036508; GO:0036509; GO:0044322; GO:1904380; GO:1904382 22225 FUN_043629 725 480 400 725 500 ptg000047l:10964101-10970459 B2GUY0 1.19e-31 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (ER mannosidase 1) (ERMan1) (Mannosidase alpha class 1B member 1) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; N-glycan processing [GO:0006491]; protein alpha-1,2-demannosylation [GO:0036508]; protein glycosylation [GO:0006486]; trimming of terminal mannose on B branch [GO:0036509]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0004571; GO:0005509; GO:0005783; GO:0005789; GO:0005975; GO:0006486; GO:0006491; GO:0016020; GO:0030433; GO:0031410; GO:0036508; GO:0036509; GO:0044322; GO:1904380; GO:1904382 22226 FUN_043628 313 212 203 388 166 ptg000047l:10957199-10961052 Q504Y2 3.64e-27 Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase) Homo sapiens (Human) bone mineralization [GO:0030282]; cell differentiation [GO:0030154]; embryonic digestive tract development [GO:0048566]; limb morphogenesis [GO:0035108]; lung alveolus development [GO:0048286]; multicellular organism growth [GO:0035264]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of bone mineralization [GO:0030501]; positive regulation of chondrocyte differentiation [GO:0032332]; protein transport [GO:0015031]; roof of mouth development [GO:0060021]; skeletal system development [GO:0001501] GO:0001501; GO:0004672; GO:0004715; GO:0005524; GO:0005576; GO:0005794; GO:0015031; GO:0018108; GO:0030154; GO:0030282; GO:0030501; GO:0032332; GO:0035108; GO:0035264; GO:0042997; GO:0048286; GO:0048566; GO:0060021 22227 FUN_010850 43 16 17 14 22 ptg000007l:3577527-3585611 Q96AY4 9.12e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22228 FUN_010850 43 16 17 14 22 ptg000007l:3577527-3585611 Q96AY4 8.97e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22229 FUN_010850 43 16 17 14 22 ptg000007l:3577527-3585611 Q96AY4 7.78e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22230 FUN_010850 43 16 17 14 22 ptg000007l:3577527-3585611 Q96AY4 1.69e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22231 FUN_010850 43 16 17 14 22 ptg000007l:3577527-3585611 Q96AY4 6.39e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22232 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 4.15e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22233 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 4.15e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22234 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 9.99e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22235 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 9.99e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22236 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 8.76e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22237 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 4.47e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22238 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.06e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22239 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 2.42e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22240 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 6.53e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22241 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 4.83e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22242 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 2.98e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22243 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.29e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22244 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 2.25e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22245 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.9e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22246 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.65e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22247 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.66e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22248 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.69e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22249 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 2.23e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22250 FUN_010856 84 41 13 66 11 ptg000007l:3622972-3627448 Q96AY4 1.1e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22251 FUN_010857 14 0 0 19 0 NA NA NA NA NA NA NA 22252 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 2.83e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22253 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 1.26e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22254 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 2.9e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22255 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 1.12e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22256 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 8.03e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22257 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 4.62e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22258 FUN_010854 42 202 19 41 6 ptg000007l:3600015-3604049 Q96AY4 1.86e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22259 FUN_043621 225 262 95 286 389 NA NA NA NA NA NA NA 22260 FUN_043620 1039 967 463 791 688 NA NA NA NA NA NA NA 22261 FUN_043623 6 5 0 10 7 NA NA NA NA NA NA NA 22262 FUN_043624 124 2382 487 23 0 NA NA NA NA NA NA NA 22263 FUN_043627 55 198 32 106 202 NA NA NA NA NA NA NA 22264 FUN_043626 791 280 333 733 460 NA NA NA NA NA NA NA 22265 FUN_041451 11 17 59 45 38 NA NA NA NA NA NA NA 22266 FUN_041452 0 24 11 20 11 NA NA NA NA NA NA NA 22267 FUN_001585 662 416 402 389 455 ntLink_6:14024380-14026473 Q8IYB1 8.52e-21 Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2) Homo sapiens (Human) NA GO:0016779; GO:0044877; GO:0045296 22268 FUN_005652 0 0 2 0 12 NA NA NA NA NA NA NA 22269 FUN_005653 0 0 15 0 3 NA NA NA NA NA NA NA 22270 FUN_041458 13 2 105 49 191 NA NA NA NA NA NA NA 22271 FUN_008909 2889 2120 1736 2234 2215 ptg000004l:439286-467709 Q9JIS1 1.61e-33 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) Rattus norvegicus (Rat) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082] GO:0006886; GO:0006887; GO:0007188; GO:0007269; GO:0010628; GO:0016081; GO:0016082; GO:0017156; GO:0017157; GO:0019904; GO:0030073; GO:0030154; GO:0030674; GO:0031267; GO:0032991; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0044877; GO:0045202; GO:0046872; GO:0048167; GO:0048788; GO:0048790; GO:0048791; GO:0050806; GO:0051649; GO:0060077; GO:0061669; GO:0097151; GO:0098684; GO:0098831; GO:0098882; GO:0098978; GO:0098982; GO:0140677; GO:0150037; GO:1903861; GO:2000463 22272 FUN_008909 2889 2120 1736 2234 2215 ptg000004l:439286-467709 Q9JIS1 1.61e-33 Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) Rattus norvegicus (Rat) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; calcium ion-regulated exocytosis of neurotransmitter [GO:0048791]; calcium-ion regulated exocytosis [GO:0017156]; cell differentiation [GO:0030154]; establishment of localization in cell [GO:0051649]; exocytosis [GO:0006887]; insulin secretion [GO:0030073]; intracellular protein transport [GO:0006886]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; positive regulation of dendrite extension [GO:1903861]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of gene expression [GO:0010628]; positive regulation of inhibitory postsynaptic potential [GO:0097151]; positive regulation of synaptic transmission [GO:0050806]; regulation of calcium-dependent activation of synaptic vesicle fusion [GO:0150037]; regulation of exocytosis [GO:0017157]; regulation of membrane potential [GO:0042391]; regulation of synaptic plasticity [GO:0048167]; spontaneous neurotransmitter secretion [GO:0061669]; synaptic vesicle docking [GO:0016081]; synaptic vesicle priming [GO:0016082] GO:0006886; GO:0006887; GO:0007188; GO:0007269; GO:0010628; GO:0016081; GO:0016082; GO:0017156; GO:0017157; GO:0019904; GO:0030073; GO:0030154; GO:0030674; GO:0031267; GO:0032991; GO:0042391; GO:0042734; GO:0042995; GO:0044325; GO:0044877; GO:0045202; GO:0046872; GO:0048167; GO:0048788; GO:0048790; GO:0048791; GO:0050806; GO:0051649; GO:0060077; GO:0061669; GO:0097151; GO:0098684; GO:0098831; GO:0098882; GO:0098978; GO:0098982; GO:0140677; GO:0150037; GO:1903861; GO:2000463 22273 FUN_008908 39698 35562 20859 38603 30049 ptg000004l:427152-433504 G8HTB6 3.32e-70 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 22274 FUN_008908 39698 35562 20859 38603 30049 ptg000004l:427152-433504 G8HTB6 4.61e-41 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 22275 FUN_008908 39698 35562 20859 38603 30049 ptg000004l:427152-433504 G8HTB6 3.64e-39 ZP domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 22276 FUN_041459 67 181 98 114 83 NA NA NA NA NA NA NA 22277 FUN_008905 8167 7531 4128 6827 5151 NA NA NA NA NA NA NA 22278 FUN_008904 477 437 237 504 406 ptg000004l:391669-392374 P14198 2.17e-32 AAC-rich mRNA clone AAC4 protein Dictyostelium discoideum (Social amoeba) NA GO:0016020 22279 FUN_008907 6706 4735 4338 7535 6520 NA NA NA NA NA NA NA 22280 FUN_008906 961 415 356 776 805 NA NA NA NA NA NA NA 22281 FUN_008901 171 265 78 253 216 NA NA NA NA NA NA NA 22282 FUN_008903 1059 1052 973 1012 533 NA NA NA NA NA NA NA 22283 FUN_028604 10 0 0 0 6 NA NA NA NA NA NA NA 22284 FUN_006854 402 283 178 299 513 NA NA NA NA NA NA NA 22285 FUN_041173 2470 3215 1381 785 956 NA NA NA NA NA NA NA 22286 FUN_041172 0 0 0 8 34 NA NA NA NA NA NA NA 22287 FUN_041171 293 132 19 341 70 NA NA NA NA NA NA NA 22288 FUN_041170 1188 1620 1211 2048 1093 NA NA NA NA NA NA NA 22289 FUN_041177 8 0 0 11 0 NA NA NA NA NA NA NA 22290 FUN_041176 388 5333 658 2829 842 NA NA NA NA NA NA NA 22291 FUN_041175 2768 18529 937 10435 3534 NA NA NA NA NA NA NA 22292 FUN_041174 0 0 1 11 3 NA NA NA NA NA NA NA 22293 FUN_041178 9 0 0 0 0 NA NA NA NA NA NA NA 22294 FUN_017983 75 13 46 150 0 NA NA NA NA NA NA NA 22295 FUN_002088 54 0 106 79 196 NA NA NA NA NA NA NA 22296 FUN_002089 67 7 13 108 51 NA NA NA NA NA NA NA 22297 FUN_002082 19126 28272 6964 23900 13925 NA NA NA NA NA NA NA 22298 FUN_002080 6716 2585 2715 7078 7415 NA NA NA NA NA NA NA 22299 FUN_002081 15 3 0 7 62 NA NA NA NA NA NA NA 22300 FUN_002086 0 1 0 0 6 NA NA NA NA NA NA NA 22301 FUN_002087 102 182 85 67 104 NA NA NA NA NA NA NA 22302 FUN_002084 150 0 27 77 62 NA NA NA NA NA NA NA 22303 FUN_002085 39 11 0 38 8 NA NA NA NA NA NA NA 22304 FUN_039812 361 525 850 2613 2003 NA NA NA NA NA NA NA 22305 FUN_011814 616 269 482 457 591 ptg000008l:1759319-1772043 Q71B07 4.12e-24 Probable C-mannosyltransferase DPY19L3 (EC 2.4.1.-) (Dpy-19-like protein 3) (Protein dpy-19 homolog 3) Mus musculus (Mouse) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan [GO:0018406] GO:0000030; GO:0005637; GO:0018406 22306 FUN_011817 41 13 44 82 55 ptg000008l:1793347-1799601 Q7RTR2 8.04e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22307 FUN_011811 1234 1204 800 1803 1681 NA NA NA NA NA NA NA 22308 FUN_011810 18698 15248 10495 15874 9829 NA NA NA NA NA NA NA 22309 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 9.22e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22310 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 1.48e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22311 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 1.29e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22312 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 1.11e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22313 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 1.36e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22314 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 5.26e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22315 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 1.26e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22316 FUN_011812 24 240 25 6 30 ptg000008l:1743087-1748532 Q96AY4 2.65e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22317 FUN_039810 127 29 410 386 297 NA NA NA NA NA NA NA 22318 FUN_011819 0 0 11 5 15 NA NA NA NA NA NA NA 22319 FUN_011818 0 0 0 0 7 NA NA NA NA NA NA NA 22320 FUN_025718 7 5 29 28 15 NA NA NA NA NA NA NA 22321 FUN_025715 0 68 0 0 0 NA NA NA NA NA NA NA 22322 FUN_025717 170 121 115 263 204 NA NA NA NA NA NA NA 22323 FUN_025716 711 799 749 879 936 NA NA NA NA NA NA NA 22324 FUN_025711 5 16 384 0 34 NA NA NA NA NA NA NA 22325 FUN_025710 150 0 24 0 0 NA NA NA NA NA NA NA 22326 FUN_025713 0 3 3 8 15 NA NA NA NA NA NA NA 22327 FUN_025712 1 1 11 5 62 NA NA NA NA NA NA NA 22328 FUN_008013 268 60561 6714 14176 21052 NA NA NA NA NA NA NA 22329 FUN_024443 1327 786 787 1266 972 ptg000018l:6407966-6418854 O18738 6.88e-29 Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)] Bos taurus (Bovine) axon guidance [GO:0007411]; morphogenesis of an epithelium [GO:0002009]; muscle attachment [GO:0016203]; nerve development [GO:0021675] GO:0002009; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005654; GO:0005737; GO:0005856; GO:0005886; GO:0007411; GO:0016011; GO:0016020; GO:0016203; GO:0021675; GO:0042383; GO:0043236; GO:0045211 22330 FUN_024440 649 162 469 186 189 ptg000018l:6356915-6361542 Q8WXK3 5.56e-37 Ankyrin repeat and SOCS box protein 13 (ASB-13) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] GO:0005829; GO:0016567; GO:0035556 22331 FUN_024441 1322 731 1198 1154 1543 NA NA NA NA NA NA NA 22332 FUN_008016 3962 1646 1457 2698 2347 NA NA NA NA NA NA NA 22333 FUN_008015 586 444 337 718 638 ptg000002l:7196226-7204516 P14912 6.44e-35 4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) Petroselinum crispum (Parsley) (Petroselinum hortense) phenylpropanoid metabolic process [GO:0009698] GO:0005524; GO:0009698; GO:0016207 22334 FUN_008014 88 157 116 153 9 NA NA NA NA NA NA NA 22335 FUN_024448 589 433 345 408 316 ptg000018l:6473942-6483386 Q6PG95 4.43e-54 Protein cramped-like (Cramped chromatin regulator homolog 1) (Hematological and neurological expressed 1-like protein) Mus musculus (Mouse) pattern specification process [GO:0007389] GO:0003677; GO:0003682; GO:0005634; GO:0007389 22336 FUN_008018 659 935 695 1094 982 ptg000002l:7254701-7260848 P18754 1.3e-73 Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1) Homo sapiens (Human) cell division [GO:0051301]; chromosome segregation [GO:0007059]; G1/S transition of mitotic cell cycle [GO:0000082]; mitotic nuclear membrane reassembly [GO:0007084]; mitotic spindle organization [GO:0007052]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225]; viral process [GO:0016032] GO:0000082; GO:0000785; GO:0000794; GO:0003682; GO:0005085; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0007052; GO:0007059; GO:0007084; GO:0007088; GO:0016032; GO:0031267; GO:0031491; GO:0031492; GO:0031965; GO:0032991; GO:0042393; GO:0043199; GO:0046982; GO:0051225; GO:0051301 22337 FUN_044040 648 6416 10940 4322 3729 NA NA NA NA NA NA NA 22338 FUN_044041 542 5809 9644 3715 3234 NA NA NA NA NA NA NA 22339 FUN_014362 272 230 101 183 149 NA NA NA NA NA NA NA 22340 FUN_014363 1288 610 122 1092 657 NA NA NA NA NA NA NA 22341 FUN_044044 496 2260 3683 2501 4279 NA NA NA NA NA NA NA 22342 FUN_014365 458 67 89 304 584 NA NA NA NA NA NA NA 22343 FUN_014366 88 32 43 87 194 NA NA NA NA NA NA NA 22344 FUN_044047 2 2 3 2 17 NA NA NA NA NA NA NA 22345 FUN_044048 37 62 60 64 166 NA NA NA NA NA NA NA 22346 FUN_018194 317 116 154 200 50 ptg000012l:5761082-5784901 Q9NBX4 2.83e-30 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 22347 FUN_022291 8037 7482 2627 3877 4154 NA NA NA NA NA NA NA 22348 FUN_022290 256 184 195 151 474 NA NA NA NA NA NA NA 22349 FUN_022293 1317 1121 539 1072 1804 NA NA NA NA NA NA NA 22350 FUN_022292 1456 748 515 1517 1688 ptg000016l:7263533-7266797 Q60803 1.92e-37 TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3) Mus musculus (Mouse) apoptotic process [GO:0006915]; innate immune response [GO:0045087]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; positive regulation of JNK cascade [GO:0046330]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of cytokine production [GO:0001817]; regulation of defense response to virus [GO:0050688]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of interferon-beta production [GO:0032648]; regulation of proteolysis [GO:0030162]; Toll signaling pathway [GO:0008063]; toll-like receptor signaling pathway [GO:0002224]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0001817; GO:0002224; GO:0005164; GO:0005739; GO:0005768; GO:0006915; GO:0008063; GO:0008270; GO:0009898; GO:0016740; GO:0019901; GO:0019903; GO:0030162; GO:0031625; GO:0031996; GO:0032088; GO:0032648; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0045087; GO:0046330; GO:0050688; GO:0070534 22351 FUN_022295 2191 1317 1542 1827 1740 NA NA NA NA NA NA NA 22352 FUN_022294 471 213 252 821 577 NA NA NA NA NA NA NA 22353 FUN_022297 462 324 206 147 671 NA NA NA NA NA NA NA 22354 FUN_022296 65 83 37 63 157 ptg000016l:7289595-7292613 Q5U4U4 1.92e-36 Protein downstream neighbor of son homolog Xenopus laevis (African clawed frog) cell division [GO:0051301]; DNA damage checkpoint signaling [GO:0000077]; DNA replication [GO:0006260]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; replication fork protection [GO:0048478] GO:0000077; GO:0005634; GO:0005657; GO:0006260; GO:0007095; GO:0030894; GO:0048478; GO:0051301 22355 FUN_022299 484 1215 94 32 90 NA NA NA NA NA NA NA 22356 FUN_022298 1074 812 1445 1113 2369 NA NA NA NA NA NA NA 22357 FUN_024194 980 1484 847 1166 1462 NA NA NA NA NA NA NA 22358 FUN_024195 1543 937 713 1564 1597 NA NA NA NA NA NA NA 22359 FUN_024196 109 54 48 16 34 NA NA NA NA NA NA NA 22360 FUN_024197 799 591 308 510 370 ptg000018l:3274337-3276962 Q6PBQ2 8.67e-61 Charged multivesicular body protein 7 (Chromatin-modifying protein 7) Danio rerio (Zebrafish) (Brachydanio rerio) exit from mitosis [GO:0010458]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; nuclear membrane reassembly [GO:0031468]; protein transport [GO:0015031]; vesicle budding from membrane [GO:0006900] GO:0000815; GO:0005635; GO:0005771; GO:0006900; GO:0010458; GO:0015031; GO:0031468; GO:0032511; GO:0045324 22361 FUN_024190 3 387 3 0 8 NA NA NA NA NA NA NA 22362 FUN_024191 17 206 16 19 33 NA NA NA NA NA NA NA 22363 FUN_024192 5154 3459 3297 3339 2175 NA NA NA NA NA NA NA 22364 FUN_024193 13382 8343 4456 5394 4237 NA NA NA NA NA NA NA 22365 FUN_024198 437 146 319 299 422 NA NA NA NA NA NA NA 22366 FUN_024199 4758 2637 3608 3148 2671 ptg000018l:3278210-3285212 O75317 1.95e-41 Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12) Homo sapiens (Human) protein deubiquitination [GO:0016579]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006511; GO:0016579; GO:0046872 22367 FUN_029373 784 289 167 307 340 NA NA NA NA NA NA NA 22368 FUN_009300 1848 0 7 6 804 NA NA NA NA NA NA NA 22369 FUN_029372 319 117 136 176 207 NA NA NA NA NA NA NA 22370 FUN_000994 4418 4678 3740 3795 1836 NA NA NA NA NA NA NA 22371 FUN_029370 0 15 0 0 0 NA NA NA NA NA NA NA 22372 FUN_000993 356 153 185 303 382 NA NA NA NA NA NA NA 22373 FUN_029374 328 133 168 167 155 NA NA NA NA NA NA NA 22374 FUN_014948 1516 1302 912 1304 818 ptg000009l:4610170-4623238 P28575 4.67e-29 Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Murine IAP-promoted placenta-expressed protein) (Protein MIPP) Mus musculus (Mouse) NA GO:0003779; GO:0005737; GO:0005856 22375 FUN_014949 1711 921 855 1657 1329 NA NA NA NA NA NA NA 22376 FUN_014944 98 32 25 89 60 NA NA NA NA NA NA NA 22377 FUN_014945 507 270 245 284 302 NA NA NA NA NA NA NA 22378 FUN_014947 3 0 0 6 21 NA NA NA NA NA NA NA 22379 FUN_014940 1273 555 568 1053 1079 ptg000009l:4525607-4529406 P46441 5.37e-31 Putative ATPase N2B (HFN2B) Haematobia irritans (Horn fly) (Conops irritans) NA GO:0005524; GO:0016887 22380 FUN_014941 188 111 132 136 100 ptg000009l:4530678-4540947 O43435 4.49e-43 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 22381 FUN_014942 407 385 236 395 371 ptg000009l:4550752-4561341 O43435 2.05e-43 T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T-box protein) Homo sapiens (Human) angiogenesis [GO:0001525]; anterior/posterior pattern specification [GO:0009952]; aorta morphogenesis [GO:0035909]; artery morphogenesis [GO:0048844]; blood vessel development [GO:0001568]; blood vessel morphogenesis [GO:0048514]; cell fate specification [GO:0001708]; cell population proliferation [GO:0008283]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to retinoic acid [GO:0071300]; cochlea morphogenesis [GO:0090103]; coronary artery morphogenesis [GO:0060982]; determination of left/right symmetry [GO:0007368]; ear morphogenesis [GO:0042471]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; enamel mineralization [GO:0070166]; epithelial cell differentiation [GO:0030855]; face morphogenesis [GO:0060325]; heart development [GO:0007507]; heart morphogenesis [GO:0003007]; inner ear morphogenesis [GO:0042472]; lymph vessel development [GO:0001945]; mesenchymal cell apoptotic process [GO:0097152]; mesoderm development [GO:0007498]; middle ear morphogenesis [GO:0042474]; muscle cell fate commitment [GO:0042693]; muscle organ development [GO:0007517]; muscle organ morphogenesis [GO:0048644]; muscle tissue morphogenesis [GO:0060415]; negative regulation of cell differentiation [GO:0045596]; negative regulation of mesenchymal cell apoptotic process [GO:2001054]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; outer ear morphogenesis [GO:0042473]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; parathyroid gland development [GO:0060017]; pattern specification process [GO:0007389]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of tongue muscle cell differentiation [GO:2001037]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of animal organ morphogenesis [GO:2000027]; regulation of transcription by RNA polymerase II [GO:0006357]; retinoic acid receptor signaling pathway [GO:0048384]; semicircular canal morphogenesis [GO:0048752]; sensory perception of sound [GO:0007605]; social behavior [GO:0035176]; soft palate development [GO:0060023]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; tongue morphogenesis [GO:0043587]; vagus nerve morphogenesis [GO:0021644] GO:0000785; GO:0000978; GO:0000981; GO:0001525; GO:0001568; GO:0001708; GO:0001755; GO:0001934; GO:0001945; GO:0002053; GO:0003007; GO:0003148; GO:0003151; GO:0003677; GO:0005634; GO:0006357; GO:0007368; GO:0007389; GO:0007498; GO:0007507; GO:0007517; GO:0007605; GO:0008283; GO:0008284; GO:0009952; GO:0021644; GO:0030855; GO:0030878; GO:0035176; GO:0035909; GO:0042471; GO:0042472; GO:0042473; GO:0042474; GO:0042475; GO:0042693; GO:0042803; GO:0043410; GO:0043565; GO:0043587; GO:0044344; GO:0045596; GO:0045893; GO:0045944; GO:0046983; GO:0048384; GO:0048514; GO:0048538; GO:0048644; GO:0048701; GO:0048703; GO:0048752; GO:0048844; GO:0050679; GO:0060017; GO:0060023; GO:0060037; GO:0060325; GO:0060415; GO:0060982; GO:0070166; GO:0071300; GO:0090103; GO:0097152; GO:1990837; GO:2000027; GO:2001037; GO:2001054 22382 FUN_014943 105 55 146 105 93 NA NA NA NA NA NA NA 22383 FUN_038763 64 11 13 15 15 ptg000027l:11045492-11053057 E9Q236 1.96e-71 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 22384 FUN_038763 64 11 13 15 15 ptg000027l:11045492-11053057 E9Q236 3.94e-33 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 22385 FUN_038760 74 237 91 203 179 ptg000027l:11015376-11027170 P20825 1.16e-61 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 22386 FUN_038761 41 30 68 107 77 ptg000027l:11039620-11040502 O15439 4.46e-101 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22387 FUN_038766 151 113 130 296 123 ptg000027l:11107639-11120367 O15439 9.65e-90 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22388 FUN_038766 151 113 130 296 123 ptg000027l:11107639-11120367 O15439 2.59e-69 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22389 FUN_038766 151 113 130 296 123 ptg000027l:11107639-11120367 O15439 5.54e-32 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 22390 FUN_038767 0 0 0 3 8 NA NA NA NA NA NA NA 22391 FUN_038764 0 8 0 0 9 NA NA NA NA NA NA NA 22392 FUN_038765 0 58 0 29 14 ptg000027l:11082418-11089715 P0CT39 7.61e-66 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 22393 FUN_038768 23 0 5 26 25 NA NA NA NA NA NA NA 22394 FUN_038769 5134 4523 1938 2876 3214 NA NA NA NA NA NA NA 22395 FUN_015011 76 51 78 92 44 ptg000009l:5251467-5252408 Q6ICH7 1.78e-55 Aspartate beta-hydroxylase domain-containing protein 2 (EC 1.14.11.-) Homo sapiens (Human) peptidyl-amino acid modification [GO:0018193] GO:0016020; GO:0018193; GO:0046872; GO:0051213 22396 FUN_015010 1680 1263 584 1078 779 ptg000009l:5244552-5250176 Q86UW9 9.1e-24 Probable E3 ubiquitin-protein ligase DTX2 (EC 2.3.2.27) (Protein deltex-2) (Deltex2) (hDTX2) (RING finger protein 58) (RING-type E3 ubiquitin transferase DTX2) Homo sapiens (Human) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005654; GO:0005737; GO:0007219; GO:0008270; GO:0016567; GO:0031965; GO:0061630 22397 FUN_015013 4571 8758 6188 25467 7275 NA NA NA NA NA NA NA 22398 FUN_015012 0 0 0 13 0 NA NA NA NA NA NA NA 22399 FUN_015015 28 33 0 46 11 NA NA NA NA NA NA NA 22400 FUN_015014 2153 4522 3742 12325 2691 NA NA NA NA NA NA NA 22401 FUN_015017 0 0 0 16 8 NA NA NA NA NA NA NA 22402 FUN_015016 18 80 1 78 70 NA NA NA NA NA NA NA 22403 FUN_015019 0 10 0 10 8 NA NA NA NA NA NA NA 22404 FUN_015018 22 22 6 28 37 NA NA NA NA NA NA NA 22405 FUN_009303 78 4 74 84 52 NA NA NA NA NA NA NA 22406 FUN_033937 1719 1765 1830 2023 1249 ptg000024l:2897535-2903217 A7SK27 2.61e-55 Probable ethanolamine kinase (EC 2.7.1.82) Nematostella vectensis (Starlet sea anemone) phosphatidylethanolamine biosynthetic process [GO:0006646]; phosphorylation [GO:0016310] GO:0004305; GO:0005524; GO:0005737; GO:0006646; GO:0016310 22407 FUN_020630 0 0 0 0 8 NA NA NA NA NA NA NA 22408 FUN_001944 9 18 14 66 63 NA NA NA NA NA NA NA 22409 FUN_022909 1224 695 456 1221 873 NA NA NA NA NA NA NA 22410 FUN_022908 1556 1082 922 1751 1757 ptg000017l:1347093-1352719 Q08DA5 9.51e-29 Pantothenate kinase 3 (EC 2.7.1.33) (Pantothenic acid kinase 3) Bos taurus (Bovine) coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310] GO:0004594; GO:0005524; GO:0005634; GO:0005829; GO:0015937; GO:0016310; GO:0019842; GO:0042803; GO:1905502 22411 FUN_022901 14 0 0 21 61 NA NA NA NA NA NA NA 22412 FUN_022900 384 199 187 122 212 NA NA NA NA NA NA NA 22413 FUN_022903 1822 1306 896 1494 861 ptg000017l:1308557-1313001 Q99N01 7.18e-49 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Rattus norvegicus (Rat) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 22414 FUN_022903 1822 1306 896 1494 861 ptg000017l:1308557-1313001 Q99N01 7.18e-49 Solute carrier organic anion transporter family member 4A1 (Organic anion-transporting polypeptide E) (OATP-E) (Sodium-independent organic anion transporter E) (Solute carrier family 21 member 12) Rattus norvegicus (Rat) sodium-independent organic anion transport [GO:0043252]; thyroid hormone metabolic process [GO:0042403] GO:0005886; GO:0008514; GO:0015132; GO:0015347; GO:0015349; GO:0042403; GO:0043252 22415 FUN_022902 3509 3690 1468 3096 1873 NA NA NA NA NA NA NA 22416 FUN_022904 26 0 63 4 511 NA NA NA NA NA NA NA 22417 FUN_022907 3361 3720 2595 2859 1955 NA NA NA NA NA NA NA 22418 FUN_022906 2353 1564 1184 1543 1159 NA NA NA NA NA NA NA 22419 FUN_027362 13 25 0 3 11 NA NA NA NA NA NA NA 22420 FUN_027363 0 28 0 0 12 NA NA NA NA NA NA NA 22421 FUN_027360 35 39 60 24 217 NA NA NA NA NA NA NA 22422 FUN_027361 0 0 11 0 0 NA NA NA NA NA NA NA 22423 FUN_027366 0 0 8 0 0 NA NA NA NA NA NA NA 22424 FUN_027367 0 0 28 0 0 NA NA NA NA NA NA NA 22425 FUN_027368 0 0 7 0 0 NA NA NA NA NA NA NA 22426 FUN_017692 25 0 8 2 19 NA NA NA NA NA NA NA 22427 FUN_040060 1618 1347 1450 1635 1417 NA NA NA NA NA NA NA 22428 FUN_018359 910 98 600 454 163 ptg000012l:8325362-8358693 Q96AY4 5.19e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22429 FUN_018359 910 98 600 454 163 ptg000012l:8325362-8358693 Q96AY4 2.47e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22430 FUN_018359 910 98 600 454 163 ptg000012l:8325362-8358693 Q96AY4 4.99e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22431 FUN_018359 910 98 600 454 163 ptg000012l:8325362-8358693 Q96AY4 8.84e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22432 FUN_026104 10162 6412 4541 8308 7005 ptg000020l:4671984-4685237 Q66HF1 1.9e-34 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) Rattus norvegicus (Rat) apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; cellular respiration [GO:0045333]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881] GO:0005739; GO:0005743; GO:0005747; GO:0005758; GO:0006120; GO:0008137; GO:0008637; GO:0009055; GO:0032981; GO:0045333; GO:0046034; GO:0046872; GO:0051537; GO:0051539; GO:0051881; GO:0072593 22433 FUN_026104 10162 6412 4541 8308 7005 ptg000020l:4671984-4685237 Q66HF1 1.9e-34 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) Rattus norvegicus (Rat) apoptotic mitochondrial changes [GO:0008637]; ATP metabolic process [GO:0046034]; cellular respiration [GO:0045333]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; reactive oxygen species metabolic process [GO:0072593]; regulation of mitochondrial membrane potential [GO:0051881] GO:0005739; GO:0005743; GO:0005747; GO:0005758; GO:0006120; GO:0008137; GO:0008637; GO:0009055; GO:0032981; GO:0045333; GO:0046034; GO:0046872; GO:0051537; GO:0051539; GO:0051881; GO:0072593 22434 FUN_026107 1938 1943 1366 2534 3962 ptg000020l:4698595-4709319 Q23381 1.04e-28 Probable methylmalonyl-CoA mutase, mitochondrial (EC 5.4.99.2) (MethylmalonylCoA mutase homolog 1) (MCM) Caenorhabditis elegans amino acid metabolic process [GO:0006520]; fatty acid metabolic process [GO:0006631]; propionate metabolic process, methylmalonyl pathway [GO:0019678] GO:0004494; GO:0005737; GO:0005739; GO:0005759; GO:0006520; GO:0006631; GO:0019678; GO:0031419; GO:0046872 22435 FUN_026107 1938 1943 1366 2534 3962 ptg000020l:4698595-4709319 Q23381 3.35e-25 Probable methylmalonyl-CoA mutase, mitochondrial (EC 5.4.99.2) (MethylmalonylCoA mutase homolog 1) (MCM) Caenorhabditis elegans amino acid metabolic process [GO:0006520]; fatty acid metabolic process [GO:0006631]; propionate metabolic process, methylmalonyl pathway [GO:0019678] GO:0004494; GO:0005737; GO:0005739; GO:0005759; GO:0006520; GO:0006631; GO:0019678; GO:0031419; GO:0046872 22436 FUN_026106 0 26 12 0 8 NA NA NA NA NA NA NA 22437 FUN_026101 1930 970 911 1777 1472 NA NA NA NA NA NA NA 22438 FUN_026100 134 23 20 114 70 ptg000020l:4619237-4622734 Q6ZSS7 3.93e-44 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 22439 FUN_026100 134 23 20 114 70 ptg000020l:4619237-4622734 Q6ZSS7 2.82e-26 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 22440 FUN_026103 540 636 262 507 401 ptg000020l:4670512-4671370 B9M6U2 7.29e-54 50S ribosomal protein L2 Geotalea daltonii (strain DSM 22248 / JCM 15807 / FRC-32) (Geobacter daltonii) translation [GO:0006412] GO:0003735; GO:0006412; GO:0015934; GO:0016740; GO:0019843 22441 FUN_026102 121 116 18 45 40 NA NA NA NA NA NA NA 22442 FUN_026109 127 0 53 126 188 NA NA NA NA NA NA NA 22443 FUN_026108 653 410 482 1481 964 ptg000020l:4710747-4724878 F8VQB6 3.24e-27 Unconventional myosin-X (Unconventional myosin-10) Mus musculus (Mouse) cell motility [GO:0048870]; cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489] GO:0000146; GO:0001726; GO:0005516; GO:0005524; GO:0005547; GO:0005730; GO:0005829; GO:0005886; GO:0005938; GO:0008360; GO:0016459; GO:0022409; GO:0030027; GO:0030175; GO:0030507; GO:0030705; GO:0031527; GO:0032433; GO:0043005; GO:0043025; GO:0048870; GO:0051015; GO:0051489; GO:0060002 22444 FUN_026108 653 410 482 1481 964 ptg000020l:4710747-4724878 F8VQB6 3.24e-27 Unconventional myosin-X (Unconventional myosin-10) Mus musculus (Mouse) cell motility [GO:0048870]; cytoskeleton-dependent intracellular transport [GO:0030705]; positive regulation of cell-cell adhesion [GO:0022409]; regulation of cell shape [GO:0008360]; regulation of filopodium assembly [GO:0051489] GO:0000146; GO:0001726; GO:0005516; GO:0005524; GO:0005547; GO:0005730; GO:0005829; GO:0005886; GO:0005938; GO:0008360; GO:0016459; GO:0022409; GO:0030027; GO:0030175; GO:0030507; GO:0030705; GO:0031527; GO:0032433; GO:0043005; GO:0043025; GO:0048870; GO:0051015; GO:0051489; GO:0060002 22445 FUN_004028 1048 2141 639 629 1210 NA NA NA NA NA NA NA 22446 FUN_004029 652 684 437 766 741 NA NA NA NA NA NA NA 22447 FUN_004026 23 15 0 47 23 NA NA NA NA NA NA NA 22448 FUN_004027 1657 1364 719 1244 1262 NA NA NA NA NA NA NA 22449 FUN_004024 179 200 311 706 128 NA NA NA NA NA NA NA 22450 FUN_004025 132 16 31 0 15 NA NA NA NA NA NA NA 22451 FUN_004020 1471 1671 2243 4733 4404 NA NA NA NA NA NA NA 22452 FUN_004021 621 47 67 1035 660 NA NA NA NA NA NA NA 22453 FUN_018074 192 11 41 71 94 NA NA NA NA NA NA NA 22454 FUN_018075 672 314 97 265 243 NA NA NA NA NA NA NA 22455 FUN_018076 22 0 0 50 0 NA NA NA NA NA NA NA 22456 FUN_018077 64 253 93 275 58 NA NA NA NA NA NA NA 22457 FUN_018070 49 43 120 0 133 NA NA NA NA NA NA NA 22458 FUN_018071 77 0 145 43 164 NA NA NA NA NA NA NA 22459 FUN_018072 22 2 31 0 51 NA NA NA NA NA NA NA 22460 FUN_018073 44 249 103 295 121 NA NA NA NA NA NA NA 22461 FUN_018078 21 29 17 27 46 NA NA NA NA NA NA NA 22462 FUN_018079 89 127 93 131 70 NA NA NA NA NA NA NA 22463 FUN_033864 1815 1112 1078 1704 1659 NA NA NA NA NA NA NA 22464 FUN_033865 3 0 12 0 43 NA NA NA NA NA NA NA 22465 FUN_033866 86 2 184 69 206 NA NA NA NA NA NA NA 22466 FUN_025459 16569 16307 13162 12613 5977 ptg000019l:2979332-2981881 Q4R4R6 8.04e-36 Cell division control protein 42 homolog (EC 3.6.5.2) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) actin filament organization [GO:0007015]; anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; establishment or maintenance of cell polarity [GO:0007163]; nervous system development [GO:0007399]; phagocytosis, engulfment [GO:0006911]; positive regulation of cytokinesis [GO:0032467]; positive regulation of pinocytosis [GO:0048549]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of filopodium assembly [GO:0051489]; small GTPase mediated signal transduction [GO:0007264] GO:0003925; GO:0005525; GO:0005737; GO:0005815; GO:0006911; GO:0007015; GO:0007163; GO:0007264; GO:0007399; GO:0009653; GO:0016020; GO:0030154; GO:0030496; GO:0031258; GO:0032467; GO:0043227; GO:0048549; GO:0051233; GO:0051489; GO:0051988; GO:0072686; GO:1900026 22467 FUN_033860 16237 19550 11853 14628 9949 NA NA NA NA NA NA NA 22468 FUN_033861 600 325 191 292 359 NA NA NA NA NA NA NA 22469 FUN_033862 161 65 124 191 201 NA NA NA NA NA NA NA 22470 FUN_033863 647 255 221 287 172 ptg000024l:2020707-2023903 Q6GNV7 3.67e-21 Solute carrier family 49 member 4 homolog (Disrupted in renal carcinoma protein 2 homolog) Xenopus laevis (African clawed frog) NA GO:0005765; GO:0022857 22471 FUN_025452 10 0 0 0 0 NA NA NA NA NA NA NA 22472 FUN_025453 14 0 0 0 0 NA NA NA NA NA NA NA 22473 FUN_025450 4220 2336 3329 3964 3633 NA NA NA NA NA NA NA 22474 FUN_025456 63 447 682 0 281 NA NA NA NA NA NA NA 22475 FUN_025457 32 0 0 0 0 NA NA NA NA NA NA NA 22476 FUN_025454 164 189 100 3401 931 NA NA NA NA NA NA NA 22477 FUN_025455 28 0 0 119 0 NA NA NA NA NA NA NA 22478 FUN_018388 0 4 16 3 70 NA NA NA NA NA NA NA 22479 FUN_018389 332 253 67 276 188 NA NA NA NA NA NA NA 22480 FUN_018386 41 0 48 49 66 NA NA NA NA NA NA NA 22481 FUN_018387 26 75 32 39 31 NA NA NA NA NA NA NA 22482 FUN_018385 0 37 74 48 51 NA NA NA NA NA NA NA 22483 FUN_018380 0 0 0 0 17 NA NA NA NA NA NA NA 22484 FUN_018381 0 20 0 96 17 NA NA NA NA NA NA NA 22485 FUN_041590 48 0 20 62 24 NA NA NA NA NA NA NA 22486 FUN_003717 1016 1003 820 1413 1382 NA NA NA NA NA NA NA 22487 FUN_040322 328 260 496 224 381 ptg000031l:7014740-7016537 A0JPE1 9.29e-27 Divergent protein kinase domain 1B (Protein FAM69B) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005789 22488 FUN_040326 2291 982 1278 1402 1511 NA NA NA NA NA NA NA 22489 FUN_018351 617 44 558 99 44 NA NA NA NA NA NA NA 22490 FUN_019385 36 338 55 277 206 ptg000015l:1752367-1754415 Q2M385 1.07e-116 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) Homo sapiens (Human) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0005576; GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 22491 FUN_019384 0 3 7 4 21 NA NA NA NA NA NA NA 22492 FUN_019387 0 1 1 3 19 NA NA NA NA NA NA NA 22493 FUN_019386 14 3 2 9 4 NA NA NA NA NA NA NA 22494 FUN_019383 13 10 0 22 7 NA NA NA NA NA NA NA 22495 FUN_040328 13223 14907 10492 4836 3956 NA NA NA NA NA NA NA 22496 FUN_040069 90 66 52 144 221 NA NA NA NA NA NA NA 22497 FUN_019389 0 0 0 9 1 NA NA NA NA NA NA NA 22498 FUN_019388 3 0 0 0 8 NA NA NA NA NA NA NA 22499 FUN_043733 24 59 68 22 0 NA NA NA NA NA NA NA 22500 FUN_018929 0 0 61 56 0 NA NA NA NA NA NA NA 22501 FUN_018923 193 46 19 0 28 NA NA NA NA NA NA NA 22502 FUN_018920 0 0 0 0 15 NA NA NA NA NA NA NA 22503 FUN_018921 20 90 79 596 86 NA NA NA NA NA NA NA 22504 FUN_018924 663 2622 113 13 198 NA NA NA NA NA NA NA 22505 FUN_018925 62 234 58 0 20 NA NA NA NA NA NA NA 22506 FUN_010907 6102 6321 3385 6127 4730 ptg000007l:4114238-4116397 R1CW23 1.66e-110 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 22507 FUN_010901 0 0 0 0 11 NA NA NA NA NA NA NA 22508 FUN_005854 0 0 0 0 27 NA NA NA NA NA NA NA 22509 FUN_005856 1844 1144 1016 1916 1561 ptg000001l:4867030-4888165 Q8BID8 4.11e-161 F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14) Mus musculus (Mouse) SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005737; GO:0006511; GO:0019005; GO:0031146 22510 FUN_005857 2403 1113 1468 2076 1627 NA NA NA NA NA NA NA 22511 FUN_005852 195 32 79 42 22 NA NA NA NA NA NA NA 22512 FUN_019038 50 0 0 0 24 NA NA NA NA NA NA NA 22513 FUN_019037 2 8 0 77 52 NA NA NA NA NA NA NA 22514 FUN_019036 0 5 0 16 51 NA NA NA NA NA NA NA 22515 FUN_019035 0 13 14 18 75 NA NA NA NA NA NA NA 22516 FUN_019033 149 0 63 17 29 NA NA NA NA NA NA NA 22517 FUN_019031 0 0 0 0 6 NA NA NA NA NA NA NA 22518 FUN_019030 0 0 0 0 36 NA NA NA NA NA NA NA 22519 FUN_034849 560 275 402 349 287 NA NA NA NA NA NA NA 22520 FUN_034848 1055 684 787 1194 1002 NA NA NA NA NA NA NA 22521 FUN_034847 476 429 459 594 741 NA NA NA NA NA NA NA 22522 FUN_034846 1320 685 941 1022 1497 NA NA NA NA NA NA NA 22523 FUN_034845 625 323 367 528 793 NA NA NA NA NA NA NA 22524 FUN_034844 180 130 105 92 207 NA NA NA NA NA NA NA 22525 FUN_034843 986 627 476 657 588 ptg000025l:720894-722959 F6QEU4 5.77e-35 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 22526 FUN_034843 986 627 476 657 588 ptg000025l:720894-722959 F6QEU4 6.54e-21 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 22527 FUN_034842 12230 7066 8901 13278 11189 ptg000025l:683710-719730 Q8N0W3 3.8e-37 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 22528 FUN_034841 179 559 236 268 254 NA NA NA NA NA NA NA 22529 FUN_034840 4031 3192 4952 4640 4213 ptg000025l:657891-678800 Q8N0W3 3.58e-35 L-fucose kinase (Fucokinase) (EC 2.7.1.52) Homo sapiens (Human) carbohydrate phosphorylation [GO:0046835]; GDP-L-fucose salvage [GO:0042352]; response to dopamine [GO:1903350] GO:0005524; GO:0005829; GO:0042352; GO:0046835; GO:0050201; GO:1903350 22530 FUN_034781 9643 7075 4168 4644 5989 ptg000025l:143698-155448 P59055 6.27e-26 Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2) Mus musculus (Mouse) apoptotic process [GO:0006915]; positive regulation of apoptotic process [GO:0043065]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0006915; GO:0043065; GO:0043565; GO:0045944 22531 FUN_035254 170 105 203 252 158 ptg000025l:5680502-5683158 O16025 1.96e-23 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 22532 FUN_006316 52 0 128 17 78 NA NA NA NA NA NA NA 22533 FUN_042111 99 75 27 65 52 NA NA NA NA NA NA NA 22534 FUN_042112 0 14 22 19 48 NA NA NA NA NA NA NA 22535 FUN_042118 1101 495 1185 381 2090 NA NA NA NA NA NA NA 22536 FUN_006319 184 54 157 199 665 NA NA NA NA NA NA NA 22537 FUN_006385 0 17 0 12 12 NA NA NA NA NA NA NA 22538 FUN_036999 596 312 320 876 1266 NA NA NA NA NA NA NA 22539 FUN_036998 0 55 0 16 17 ptg000026l:4411932-4416146 P47972 1.2e-22 Neuronal pentraxin-2 (NP2) (Neuronal pentraxin II) (NP-II) Homo sapiens (Human) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005576; GO:0007268; GO:0008306; GO:0030246; GO:0046872; GO:0098962; GO:0098978 22540 FUN_036997 430 261 238 336 217 NA NA NA NA NA NA NA 22541 FUN_036996 683 305 476 585 693 NA NA NA NA NA NA NA 22542 FUN_036995 571 580 215 226 216 NA NA NA NA NA NA NA 22543 FUN_036994 1047 1304 440 858 697 NA NA NA NA NA NA NA 22544 FUN_036993 912 457 570 789 1088 NA NA NA NA NA NA NA 22545 FUN_036992 0 20 53 0 0 NA NA NA NA NA NA NA 22546 FUN_036991 46 82 1134 97 23 NA NA NA NA NA NA NA 22547 FUN_036990 303 342 18 93 142 NA NA NA NA NA NA NA 22548 FUN_035718 713 444 348 688 507 NA NA NA NA NA NA NA 22549 FUN_035719 2617 1260 1505 2408 1607 ptg000025l:10940104-10962336 Q7ZVR8 3.19e-26 Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA processing [GO:0006397]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380] GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0006397; GO:0008380; GO:0043484; GO:1990904 22550 FUN_035714 4876 4681 2406 3457 2555 NA NA NA NA NA NA NA 22551 FUN_035715 750 491 364 500 337 ptg000025l:10916271-10918164 O95336 3.84e-54 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051] GO:0005737; GO:0005829; GO:0005975; GO:0006098; GO:0009051; GO:0017057; GO:0070062 22552 FUN_035716 975 787 540 570 751 NA NA NA NA NA NA NA 22553 FUN_035717 738 519 457 461 665 NA NA NA NA NA NA NA 22554 FUN_035710 41 70 18 31 23 NA NA NA NA NA NA NA 22555 FUN_035711 0 0 8 8 27 NA NA NA NA NA NA NA 22556 FUN_035712 25 8 2 4 16 NA NA NA NA NA NA NA 22557 FUN_035713 31 129 40 44 17 NA NA NA NA NA NA NA 22558 FUN_029815 19 217 166 99 84 NA NA NA NA NA NA NA 22559 FUN_003849 3755 3080 2441 5116 4795 NA NA NA NA NA NA NA 22560 FUN_004818 85 49 38 42 77 NA NA NA NA NA NA NA 22561 FUN_004817 285 921 180 602 582 ntLink_8:27363503-27368965 Q9VIP7 5.13e-24 Alkaline ceramidase (AlkCDase) (EC 3.5.1.23) (Alkaline N-acylsphingosine amidohydrolase) (Alkaline acylsphingosine deacylase) (Protein brainwashing) Drosophila melanogaster (Fruit fly) brain development [GO:0007420]; ceramide catabolic process [GO:0046514]; regulation of lipid metabolic process [GO:0019216]; sphingolipid metabolic process [GO:0006665] GO:0005783; GO:0006665; GO:0007420; GO:0016020; GO:0017040; GO:0019216; GO:0046514; GO:0046872; GO:0102121 22562 FUN_004816 1364 986 997 1653 1707 NA NA NA NA NA NA NA 22563 FUN_004815 0 0 13 11 0 NA NA NA NA NA NA NA 22564 FUN_003841 727 839 158 774 342 NA NA NA NA NA NA NA 22565 FUN_004812 1417 0 521 0 31 ntLink_8:27280540-27285896 Q54T82 1.95e-22 Putative leucine-rich repeat-containing protein DDB_G0281931 Dictyostelium discoideum (Social amoeba) NA GO:0016020 22566 FUN_003842 370 314 69 467 276 NA NA NA NA NA NA NA 22567 FUN_031413 147 437 179 98 271 ptg000023l:20858769-20870576 Q7RTR2 9.29e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22568 FUN_031413 147 437 179 98 271 ptg000023l:20858769-20870576 Q7RTR2 5.86e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22569 FUN_031413 147 437 179 98 271 ptg000023l:20858769-20870576 Q7RTR2 8.93e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22570 FUN_031413 147 437 179 98 271 ptg000023l:20858769-20870576 Q7RTR2 7.98e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22571 FUN_031413 147 437 179 98 271 ptg000023l:20858769-20870576 Q7RTR2 6.42e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22572 FUN_031413 147 437 179 98 271 ptg000023l:20858769-20870576 Q7RTR2 9.86e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22573 FUN_031412 0 44 13 0 27 NA NA NA NA NA NA NA 22574 FUN_031410 8 0 7 4 26 ptg000023l:20805189-20810082 Q7RTR2 1.51e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22575 FUN_031410 8 0 7 4 26 ptg000023l:20805189-20810082 Q7RTR2 3.59e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22576 FUN_031410 8 0 7 4 26 ptg000023l:20805189-20810082 Q7RTR2 5.57e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22577 FUN_031410 8 0 7 4 26 ptg000023l:20805189-20810082 Q7RTR2 1.41e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22578 FUN_031410 8 0 7 4 26 ptg000023l:20805189-20810082 Q7RTR2 4.83e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22579 FUN_031410 8 0 7 4 26 ptg000023l:20805189-20810082 Q7RTR2 2.97e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22580 FUN_031415 0 0 6 0 0 NA NA NA NA NA NA NA 22581 FUN_031414 7 52 3 117 0 NA NA NA NA NA NA NA 22582 FUN_031419 457 282 316 612 340 ptg000023l:20920637-20948838 Q7RTR2 1.28e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22583 FUN_031419 457 282 316 612 340 ptg000023l:20920637-20948838 Q7RTR2 2.46e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22584 FUN_031419 457 282 316 612 340 ptg000023l:20920637-20948838 Q7RTR2 2.59e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22585 FUN_031419 457 282 316 612 340 ptg000023l:20920637-20948838 Q7RTR2 4.8e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22586 FUN_031419 457 282 316 612 340 ptg000023l:20920637-20948838 Q7RTR2 1.98e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22587 FUN_031419 457 282 316 612 340 ptg000023l:20920637-20948838 Q7RTR2 1.25e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22588 FUN_037716 0 0 0 0 17 NA NA NA NA NA NA NA 22589 FUN_037717 10 60 9 17 16 ptg000026l:12727580-12730142 O54991 6.44e-34 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 22590 FUN_037715 0 0 30 10 24 ptg000026l:12711861-12715653 O54991 2.77e-30 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 22591 FUN_037712 557 243 180 588 283 ptg000026l:12685823-12688969 P78357 2.71e-30 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 22592 FUN_037713 333 177 170 505 114 ptg000026l:12693091-12696916 Q9UHC6 2.78e-32 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 22593 FUN_037710 2909 2809 1708 1764 1548 NA NA NA NA NA NA NA 22594 FUN_037711 1897 2165 2538 1491 1925 NA NA NA NA NA NA NA 22595 FUN_023032 1267 665 1701 3417 1448 NA NA NA NA NA NA NA 22596 FUN_025458 1408 538 352 1941 349 NA NA NA NA NA NA NA 22597 FUN_023033 4869 3346 3264 7563 4567 ptg000017l:2872000-2903565 Q8CGE9 3.7e-25 Regulator of G-protein signaling 12 (RGS12) Mus musculus (Mouse) regulation of G protein-coupled receptor signaling pathway [GO:0008277]; signal transduction [GO:0007165]; termination of G protein-coupled receptor signaling pathway [GO:0038032] GO:0001965; GO:0005096; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0008277; GO:0030425; GO:0030695; GO:0032991; GO:0038032; GO:0043025; GO:0045202; GO:0097440 22598 FUN_033868 3674 2652 1955 2497 2319 NA NA NA NA NA NA NA 22599 FUN_033869 262 171 146 262 89 ptg000024l:2094536-2099702 E7FAM5 2.08e-40 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 22600 FUN_033869 262 171 146 262 89 ptg000024l:2094536-2099702 E7FAM5 3.06e-34 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 22601 FUN_033869 262 171 146 262 89 ptg000024l:2094536-2099702 E7FAM5 2.59e-32 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 22602 FUN_033869 262 171 146 262 89 ptg000024l:2094536-2099702 E7FAM5 5.02e-28 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 22603 FUN_032290 443 366 249 203 301 NA NA NA NA NA NA NA 22604 FUN_032291 1856 1193 1220 1322 1659 NA NA NA NA NA NA NA 22605 FUN_032292 212 146 0 25 116 NA NA NA NA NA NA NA 22606 FUN_032293 2928 2248 940 2587 2835 NA NA NA NA NA NA NA 22607 FUN_032294 2072 1112 1102 2355 1806 NA NA NA NA NA NA NA 22608 FUN_032295 7782 7851 5484 6807 6549 NA NA NA NA NA NA NA 22609 FUN_032296 3912 3123 1849 4114 2535 NA NA NA NA NA NA NA 22610 FUN_032297 1889 1004 1900 850 522 NA NA NA NA NA NA NA 22611 FUN_032298 2132 1649 1032 1170 1205 NA NA NA NA NA NA NA 22612 FUN_032299 3496 1202 1929 2307 2383 NA NA NA NA NA NA NA 22613 FUN_008251 724 282 456 520 514 NA NA NA NA NA NA NA 22614 FUN_008250 5327 4450 2930 3759 3326 NA NA NA NA NA NA NA 22615 FUN_008253 3618 2406 1377 1511 921 NA NA NA NA NA NA NA 22616 FUN_008252 2207 1526 739 1196 813 NA NA NA NA NA NA NA 22617 FUN_008255 37 7 32 62 71 NA NA NA NA NA NA NA 22618 FUN_008257 1559 1129 940 1697 1546 ptg000002l:9713105-9719592 P46824 7.81e-28 Kinesin light chain (KLC) Drosophila melanogaster (Fruit fly) dorsal appendage formation [GO:0046843]; microtubule-based movement [GO:0007018] GO:0005737; GO:0005871; GO:0005874; GO:0007018; GO:0019894; GO:0046843 22619 FUN_008256 631 532 209 631 687 ptg000002l:9708162-9711669 Q9Y6V7 1.56e-54 Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49) Homo sapiens (Human) positive regulation of cell growth [GO:0030307]; regulation of rRNA stability [GO:0044357]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0006364; GO:0016887; GO:0030307; GO:0044357 22620 FUN_008256 631 532 209 631 687 ptg000002l:9708162-9711669 Q9Y6V7 2.17e-47 Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49) Homo sapiens (Human) positive regulation of cell growth [GO:0030307]; regulation of rRNA stability [GO:0044357]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0006364; GO:0016887; GO:0030307; GO:0044357 22621 FUN_008256 631 532 209 631 687 ptg000002l:9708162-9711669 Q9Y6V7 6.23e-32 Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49) Homo sapiens (Human) positive regulation of cell growth [GO:0030307]; regulation of rRNA stability [GO:0044357]; rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0006364; GO:0016887; GO:0030307; GO:0044357 22622 FUN_008259 2697 1479 1376 1313 618 ptg000002l:9736758-9743903 O00255 8.45e-21 Menin Homo sapiens (Human) brain development [GO:0007420]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose stimulus [GO:0071333]; cellular response to peptide hormone stimulus [GO:0071375]; chromatin organization [GO:0006325]; decidualization [GO:0046697]; DNA repair [GO:0006281]; histone H3-K4 methylation [GO:0051568]; MAPK cascade [GO:0000165]; mitotic cell cycle [GO:0000278]; negative regulation of cell cycle [GO:0045786]; negative regulation of cell cycle G1/S phase transition [GO:1902807]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cell-substrate adhesion [GO:0010812]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of JNK cascade [GO:0046329]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of telomerase activity [GO:0051974]; negative regulation of transcription by RNA polymerase II [GO:0000122]; osteoblast development [GO:0002076]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; regulation of activin receptor signaling pathway [GO:0032925]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of type B pancreatic cell proliferation [GO:0061469]; response to gamma radiation [GO:0010332]; response to transforming growth factor beta [GO:0071559]; response to UV [GO:0009411]; T-helper 2 cell differentiation [GO:0045064]; type B pancreatic cell differentiation [GO:0003309] GO:0000122; GO:0000165; GO:0000278; GO:0000400; GO:0000403; GO:0000781; GO:0000785; GO:0000976; GO:0001933; GO:0002076; GO:0003309; GO:0003682; GO:0003690; GO:0005634; GO:0005654; GO:0005737; GO:0005788; GO:0005829; GO:0006281; GO:0006325; GO:0006357; GO:0006974; GO:0007420; GO:0008285; GO:0009411; GO:0010332; GO:0010812; GO:0016363; GO:0017053; GO:0030511; GO:0030674; GO:0032154; GO:0032925; GO:0032991; GO:0035097; GO:0043433; GO:0044665; GO:0045064; GO:0045668; GO:0045736; GO:0045786; GO:0045892; GO:0045944; GO:0046329; GO:0046697; GO:0047485; GO:0050680; GO:0051219; GO:0051568; GO:0051974; GO:0061469; GO:0070412; GO:0071333; GO:0071339; GO:0071375; GO:0071559; GO:1902807 22623 FUN_011384 0 0 0 0 20 NA NA NA NA NA NA NA 22624 FUN_011383 0 0 45 3 41 NA NA NA NA NA NA NA 22625 FUN_011382 0 0 0 0 20 NA NA NA NA NA NA NA 22626 FUN_000004 7 7 28 4 178 NA NA NA NA NA NA NA 22627 FUN_005037 780 1683 796 1674 1382 NA NA NA NA NA NA NA 22628 FUN_005034 535 1606 890 408 170 NA NA NA NA NA NA NA 22629 FUN_005035 388 369 346 496 432 NA NA NA NA NA NA NA 22630 FUN_005032 6658 5332 4963 8965 7350 ntLink_8:30220775-30251309 B6ZLK2 1.53e-58 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 22631 FUN_005032 6658 5332 4963 8965 7350 ntLink_8:30220775-30251309 B6ZLK2 8.03e-23 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 22632 FUN_005032 6658 5332 4963 8965 7350 ntLink_8:30220775-30251309 B6ZLK2 3.89e-22 Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.12) (ATP-dependent helicase CHD1) Gallus gallus (Chicken) chromatin remodeling [GO:0006338]; nucleosome organization [GO:0034728]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000775; GO:0000785; GO:0003677; GO:0003682; GO:0004386; GO:0005524; GO:0005634; GO:0006338; GO:0006357; GO:0016887; GO:0034728; GO:0042393; GO:0140658 22633 FUN_005033 1352 1757 669 1293 970 NA NA NA NA NA NA NA 22634 FUN_005030 18 28 3 17 7 ntLink_8:30203299-30204283 P33206 3.2e-43 Forkhead box protein A4-B (FoxA4-B) (FoxA4b) (Fork head domain-related protein 1') (FKH-1) (Forkhead protein 1) (xFD-1') (xFKH1) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0007399; GO:0019904; GO:0030154; GO:0043565; GO:0045892 22635 FUN_005031 11 80 19 17 25 NA NA NA NA NA NA NA 22636 FUN_000008 7 15 12 11 46 NA NA NA NA NA NA NA 22637 FUN_000009 136 35 89 142 294 NA NA NA NA NA NA NA 22638 FUN_005038 3541 5317 3099 5502 3610 NA NA NA NA NA NA NA 22639 FUN_005039 0 0 0 10 0 NA NA NA NA NA NA NA 22640 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 1.01e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22641 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 4.82e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22642 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 2.47e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22643 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 9.41e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22644 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 1.78e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22645 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 3.07e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22646 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 3.61e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22647 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 2.21e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22648 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 3e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22649 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 4.83e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22650 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 1.47e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22651 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 1.93e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22652 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 5.08e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22653 FUN_014267 3934 677 1654 999 394 ptg000008l:34275169-34283162 P10079 1.93e-25 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22654 FUN_032878 73 117 46 170 87 NA NA NA NA NA NA NA 22655 FUN_032879 2463 1829 1211 1421 1007 NA NA NA NA NA NA NA 22656 FUN_032874 8065 4533 2101 6979 4834 NA NA NA NA NA NA NA 22657 FUN_032875 5091 3257 1499 2868 2807 NA NA NA NA NA NA NA 22658 FUN_032876 48 31 46 40 75 NA NA NA NA NA NA NA 22659 FUN_032877 1993 1191 826 1834 1634 NA NA NA NA NA NA NA 22660 FUN_032870 95 131 81 113 50 ptg000023l:36990416-36991334 P79218 1.45e-21 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 22661 FUN_032871 19 76 44 26 26 ptg000023l:37007930-37008848 P41146 9.79e-22 Nociceptin receptor (Kappa-type 3 opioid receptor) (KOR-3) (Orphanin FQ receptor) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; conditioned place preference [GO:1990708]; eating behavior [GO:0042755]; estrous cycle [GO:0044849]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0106072]; negative regulation of blood pressure [GO:0045776]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of voltage-gated calcium channel activity [GO:1901386]; neuropeptide signaling pathway [GO:0007218]; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway [GO:0051482]; positive regulation of gastric acid secretion [GO:0060454]; positive regulation of sensory perception of pain [GO:1904058]; positive regulation of urine volume [GO:0035810]; regulation of locomotor rhythm [GO:1904059]; response to estradiol [GO:0032355]; sensory perception [GO:0007600]; sensory perception of pain [GO:0019233] GO:0001626; GO:0004930; GO:0005886; GO:0007193; GO:0007218; GO:0007600; GO:0008022; GO:0019233; GO:0031410; GO:0032355; GO:0035810; GO:0038003; GO:0042277; GO:0042755; GO:0042923; GO:0043005; GO:0043951; GO:0044849; GO:0045776; GO:0051482; GO:0060454; GO:0106072; GO:1901386; GO:1904058; GO:1904059; GO:1990708 22662 FUN_032873 2487 1467 1178 2575 2415 NA NA NA NA NA NA NA 22663 FUN_008854 271 135 188 261 355 NA NA NA NA NA NA NA 22664 FUN_019444 25 2 100 0 78 NA NA NA NA NA NA NA 22665 FUN_008783 16 87 52 34 113 NA NA NA NA NA NA NA 22666 FUN_008782 238 317 218 522 722 NA NA NA NA NA NA NA 22667 FUN_008781 44139 108480 62111 101690 21269 NA NA NA NA NA NA NA 22668 FUN_008780 254 252 148 299 416 NA NA NA NA NA NA NA 22669 FUN_008785 3 0 0 6 0 NA NA NA NA NA NA NA 22670 FUN_008784 9 0 6 28 8 NA NA NA NA NA NA NA 22671 FUN_023780 59 82 46 73 61 NA NA NA NA NA NA NA 22672 FUN_023781 0 17 6 12 18 NA NA NA NA NA NA NA 22673 FUN_041391 4 7 0 14 0 NA NA NA NA NA NA NA 22674 FUN_040239 3018 1956 2145 4414 2479 NA NA NA NA NA NA NA 22675 FUN_040238 990 917 704 738 712 ptg000031l:5756957-5761966 Q9CQS4 2.03e-39 Mitochondrial outer membrane protein SLC25A46 (Solute carrier family 25 member 46) Mus musculus (Mouse) autophagy of mitochondrion [GO:0000422]; axon development [GO:0061564]; cerebellar Purkinje cell differentiation [GO:0021702]; cristae formation [GO:0042407]; dendrite development [GO:0016358]; locomotion involved in locomotory behavior [GO:0031987]; mitochondrial fission [GO:0000266]; mitochondrial membrane fission [GO:0090149]; mitochondrial transport [GO:0006839]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; optic nerve development [GO:0021554]; peripheral nervous system neuron axonogenesis [GO:0048936]; phospholipid homeostasis [GO:0055091]; protein-containing complex assembly [GO:0065003]; respiratory chain complex IV assembly [GO:0008535]; synapse assembly [GO:0007416] GO:0000266; GO:0000422; GO:0005739; GO:0005741; GO:0006839; GO:0007005; GO:0007416; GO:0008535; GO:0016358; GO:0021554; GO:0021702; GO:0022011; GO:0031987; GO:0042407; GO:0044877; GO:0048936; GO:0055091; GO:0061564; GO:0065003; GO:0090149 22676 FUN_040233 156 149 155 137 120 NA NA NA NA NA NA NA 22677 FUN_040232 314 66 125 60 115 ptg000031l:5709091-5714320 Q8TEQ8 5.18e-43 GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0006506; GO:0016020; GO:0051377 22678 FUN_040232 314 66 125 60 115 ptg000031l:5709091-5714320 Q8TEQ8 2.16e-22 GPI ethanolamine phosphate transferase 3 (EC 2.-.-.-) (Phosphatidylinositol-glycan biosynthesis class O protein) (PIG-O) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506] GO:0005789; GO:0006506; GO:0016020; GO:0051377 22679 FUN_040230 626 372 152 373 413 NA NA NA NA NA NA NA 22680 FUN_040237 13726 11431 6583 9261 4070 NA NA NA NA NA NA NA 22681 FUN_040235 4056 7173 2454 2703 3592 NA NA NA NA NA NA NA 22682 FUN_040234 390 409 378 244 167 NA NA NA NA NA NA NA 22683 FUN_041395 0 0 0 14 9 NA NA NA NA NA NA NA 22684 FUN_034438 45 23 0 0 0 NA NA NA NA NA NA NA 22685 FUN_034439 30 0 6 6 153 NA NA NA NA NA NA NA 22686 FUN_011526 12 0 16 19 50 NA NA NA NA NA NA NA 22687 FUN_019440 2 222 339 371 27 NA NA NA NA NA NA NA 22688 FUN_014939 2591 5637 1166 5404 4393 NA NA NA NA NA NA NA 22689 FUN_002338 646 0 255 587 447 NA NA NA NA NA NA NA 22690 FUN_002339 1649 4 72 343 128 ntLink_8:197288-202814 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22691 FUN_002339 1649 4 72 343 128 ntLink_8:197288-202814 Q96AY4 1.45e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22692 FUN_002339 1649 4 72 343 128 ntLink_8:197288-202814 Q96AY4 7.63e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22693 FUN_002339 1649 4 72 343 128 ntLink_8:197288-202814 Q96AY4 5.68e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22694 FUN_002339 1649 4 72 343 128 ntLink_8:197288-202814 Q96AY4 1.87e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22695 FUN_002339 1649 4 72 343 128 ntLink_8:197288-202814 Q96AY4 3.09e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22696 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.71e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22697 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 2.81e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22698 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.63e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22699 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 3.52e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22700 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 9.48e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22701 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.49e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22702 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 4.22e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22703 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 6.35e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22704 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.3e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22705 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 7.09e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22706 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 8.68e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22707 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 7.03e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22708 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 4.2e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22709 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 7.62e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22710 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 2.29e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22711 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.23e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22712 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.42e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22713 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 4.27e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22714 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 3.27e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22715 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.06e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22716 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 5.79e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22717 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 1.88e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22718 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 6.92e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22719 FUN_002335 846 15 130 516 204 ntLink_8:151747-157357 Q80XJ3 4.43e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 22720 FUN_002336 1887 3 7 947 784 NA NA NA NA NA NA NA 22721 FUN_002332 314 0 171 70 0 NA NA NA NA NA NA NA 22722 FUN_014540 5 44 24 10 33 NA NA NA NA NA NA NA 22723 FUN_014541 79 62 45 56 94 NA NA NA NA NA NA NA 22724 FUN_014542 41313 48193 29455 34185 20551 NA NA NA NA NA NA NA 22725 FUN_014543 4282 3024 1996 2566 1696 NA NA NA NA NA NA NA 22726 FUN_014544 374 113 226 278 553 ptg000009l:1093188-1095307 A2VDX7 2.06e-46 Exonuclease V (Exo V) (EC 3.1.-.-) (Defects in morphology protein 1 homolog) Bos taurus (Bovine) interstrand cross-link repair [GO:0036297] GO:0003677; GO:0005634; GO:0005654; GO:0005829; GO:0036297; GO:0045145; GO:0046872; GO:0051539 22727 FUN_014545 942 625 349 669 778 NA NA NA NA NA NA NA 22728 FUN_014549 3 0 0 4 10 NA NA NA NA NA NA NA 22729 FUN_013320 1877 2908 39 483 1052 NA NA NA NA NA NA NA 22730 FUN_000875 365 1588 7 114 988 NA NA NA NA NA NA NA 22731 FUN_000874 238 441 91 254 260 NA NA NA NA NA NA NA 22732 FUN_000877 2465 2353 1577 2529 1315 NA NA NA NA NA NA NA 22733 FUN_000876 2793 2910 1996 1858 3052 NA NA NA NA NA NA NA 22734 FUN_000871 326 431 77 232 272 ntLink_6:5510289-5523855 Q03650 1.13e-36 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 22735 FUN_000871 326 431 77 232 272 ntLink_6:5510289-5523855 Q03650 6.63e-29 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 22736 FUN_000870 300 460 43 340 388 ntLink_6:5508853-5509948 P55039 0 Developmentally-regulated GTP-binding protein 2 (DRG-2) (Translation factor GTPase DRG2) (TRAFAC GTPase DRG2) (EC 3.6.5.-) Homo sapiens (Human) cytoplasmic translation [GO:0002181]; signal transduction [GO:0007165] GO:0002181; GO:0003723; GO:0003924; GO:0005525; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0007165; GO:0016020; GO:0043231; GO:0046872 22737 FUN_000873 1400 1526 2185 1750 1578 ntLink_6:5533133-5537301 Q8R087 8.97e-28 Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein 4-beta-galactosyltransferase) (EC 2.4.1.133) (Xylosylprotein beta-1,4-galactosyltransferase) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycosaminoglycan biosynthetic process [GO:0006024]; glycosylation [GO:0070085]; negative regulation of fibroblast proliferation [GO:0048147]; protein N-linked glycosylation [GO:0006487]; proteoglycan biosynthetic process [GO:0030166]; proteoglycan metabolic process [GO:0006029]; supramolecular fiber organization [GO:0097435] GO:0003831; GO:0005794; GO:0005975; GO:0006024; GO:0006029; GO:0006487; GO:0008378; GO:0016020; GO:0030145; GO:0030166; GO:0032580; GO:0046525; GO:0048147; GO:0070085; GO:0097435 22738 FUN_000872 1109 1385 1183 1696 1307 NA NA NA NA NA NA NA 22739 FUN_000879 638 449 233 656 507 NA NA NA NA NA NA NA 22740 FUN_000878 121 196 80 130 230 NA NA NA NA NA NA NA 22741 FUN_023195 339 214 145 262 83 NA NA NA NA NA NA NA 22742 FUN_023194 62 41 68 68 30 ptg000017l:4792452-4796494 Q9JME2 3.77e-28 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Mus musculus (Mouse) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 22743 FUN_023197 34 0 0 10 34 NA NA NA NA NA NA NA 22744 FUN_023196 348 357 568 249 279 NA NA NA NA NA NA NA 22745 FUN_023190 54 53 19 144 458 NA NA NA NA NA NA NA 22746 FUN_023193 178 179 136 120 91 NA NA NA NA NA NA NA 22747 FUN_023192 47 36 48 50 41 NA NA NA NA NA NA NA 22748 FUN_023199 6902 5623 3411 4877 4924 NA NA NA NA NA NA NA 22749 FUN_023198 1336 1339 1017 2453 1826 NA NA NA NA NA NA NA 22750 FUN_022828 1897 670 47 852 54 NA NA NA NA NA NA NA 22751 FUN_022826 2218 2049 870 1823 1075 NA NA NA NA NA NA NA 22752 FUN_022827 1942 2108 1550 1559 1290 ptg000017l:394736-397181 Q0IJ33 2.71e-50 E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) response to unfolded protein [GO:0006986] GO:0005789; GO:0006986; GO:0046872; GO:0061630 22753 FUN_022827 1942 2108 1550 1559 1290 ptg000017l:394736-397181 Q0IJ33 1.8e-32 E3 ubiquitin-protein ligase TM129 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TM129) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) response to unfolded protein [GO:0006986] GO:0005789; GO:0006986; GO:0046872; GO:0061630 22754 FUN_022824 3369 3455 2539 3490 2325 ptg000017l:351767-370067 B2RW38 4.21e-47 Cilia- and flagella-associated protein 58 Mus musculus (Mouse) cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; Notch signaling pathway [GO:0007219]; protein localization to motile cilium [GO:0120229]; sperm axoneme assembly [GO:0007288]; sperm flagellum assembly [GO:0120316]; sperm mitochondrial sheath assembly [GO:0120317] GO:0005737; GO:0005813; GO:0005856; GO:0007219; GO:0007288; GO:0030317; GO:0036126; GO:0060271; GO:0097225; GO:0120229; GO:0120316; GO:0120317 22755 FUN_022824 3369 3455 2539 3490 2325 ptg000017l:351767-370067 B2RW38 3.58e-25 Cilia- and flagella-associated protein 58 Mus musculus (Mouse) cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; Notch signaling pathway [GO:0007219]; protein localization to motile cilium [GO:0120229]; sperm axoneme assembly [GO:0007288]; sperm flagellum assembly [GO:0120316]; sperm mitochondrial sheath assembly [GO:0120317] GO:0005737; GO:0005813; GO:0005856; GO:0007219; GO:0007288; GO:0030317; GO:0036126; GO:0060271; GO:0097225; GO:0120229; GO:0120316; GO:0120317 22756 FUN_022824 3369 3455 2539 3490 2325 ptg000017l:351767-370067 B2RW38 9.62e-24 Cilia- and flagella-associated protein 58 Mus musculus (Mouse) cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; Notch signaling pathway [GO:0007219]; protein localization to motile cilium [GO:0120229]; sperm axoneme assembly [GO:0007288]; sperm flagellum assembly [GO:0120316]; sperm mitochondrial sheath assembly [GO:0120317] GO:0005737; GO:0005813; GO:0005856; GO:0007219; GO:0007288; GO:0030317; GO:0036126; GO:0060271; GO:0097225; GO:0120229; GO:0120316; GO:0120317 22757 FUN_022824 3369 3455 2539 3490 2325 ptg000017l:351767-370067 B2RW38 2.6e-22 Cilia- and flagella-associated protein 58 Mus musculus (Mouse) cilium assembly [GO:0060271]; flagellated sperm motility [GO:0030317]; Notch signaling pathway [GO:0007219]; protein localization to motile cilium [GO:0120229]; sperm axoneme assembly [GO:0007288]; sperm flagellum assembly [GO:0120316]; sperm mitochondrial sheath assembly [GO:0120317] GO:0005737; GO:0005813; GO:0005856; GO:0007219; GO:0007288; GO:0030317; GO:0036126; GO:0060271; GO:0097225; GO:0120229; GO:0120316; GO:0120317 22758 FUN_022825 513 429 510 530 537 ptg000017l:374164-382405 O43156 2.81e-40 TELO2-interacting protein 1 homolog (Protein SMG10) Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of DNA damage checkpoint [GO:2000003]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006] GO:0005634; GO:0005737; GO:0006338; GO:0031931; GO:0031932; GO:0032006; GO:0050821; GO:0070209; GO:0110078; GO:2000003 22759 FUN_022825 513 429 510 530 537 ptg000017l:374164-382405 O43156 3.51e-25 TELO2-interacting protein 1 homolog (Protein SMG10) Homo sapiens (Human) chromatin remodeling [GO:0006338]; positive regulation of DNA damage checkpoint [GO:2000003]; protein stabilization [GO:0050821]; regulation of TOR signaling [GO:0032006] GO:0005634; GO:0005737; GO:0006338; GO:0031931; GO:0031932; GO:0032006; GO:0050821; GO:0070209; GO:0110078; GO:2000003 22760 FUN_022822 215 335 215 272 165 NA NA NA NA NA NA NA 22761 FUN_022823 778 935 502 1688 1372 NA NA NA NA NA NA NA 22762 FUN_022820 4275 2443 1700 3709 2021 NA NA NA NA NA NA NA 22763 FUN_022821 1431 922 808 1514 1307 NA NA NA NA NA NA NA 22764 FUN_029768 542 488 196 366 303 NA NA NA NA NA NA NA 22765 FUN_029769 10 6 0 0 1 NA NA NA NA NA NA NA 22766 FUN_029760 1055 273 248 747 507 NA NA NA NA NA NA NA 22767 FUN_029761 7736 7802 4804 7465 7815 NA NA NA NA NA NA NA 22768 FUN_029763 2676 1600 1685 3059 2086 NA NA NA NA NA NA NA 22769 FUN_029764 0 0 13 21 0 NA NA NA NA NA NA NA 22770 FUN_011406 0 0 0 0 8 NA NA NA NA NA NA NA 22771 FUN_029767 525 344 212 310 207 NA NA NA NA NA NA NA 22772 FUN_016379 77 7 52 6 43 NA NA NA NA NA NA NA 22773 FUN_016378 23 0 0 17 0 NA NA NA NA NA NA NA 22774 FUN_013325 3511 4724 3247 2482 2136 NA NA NA NA NA NA NA 22775 FUN_016371 560 450 296 734 307 ptg000011l:2369440-2370759 P42587 8.51e-34 Homeobox protein XENK-2 Xenopus laevis (African clawed frog) NA GO:0000981; GO:0003677; GO:0005634 22776 FUN_016370 717 644 303 319 307 ptg000011l:2361833-2362493 Q9CQM0 5.42e-44 Nicolin-1 (Tubulin polyglutamylase complex subunit 5) (PGs5) (p24) Mus musculus (Mouse) NA GO:0005654; GO:0005829; GO:0005874 22777 FUN_016373 258 154 137 326 143 ptg000011l:2410389-2411664 Q90481 9.48e-26 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 22778 FUN_016372 28 26 0 34 18 ptg000011l:2388877-2393430 Q90481 2.17e-21 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 22779 FUN_016375 107 37 18 126 96 ptg000011l:2436221-2437361 Q90481 1.94e-37 Homeobox protein Nkx-2.2a (Homeobox protein NK-2 homolog B-A) Danio rerio (Zebrafish) (Brachydanio rerio) cell differentiation [GO:0030154]; endocrine pancreas development [GO:0031018]; floor plate development [GO:0033504]; floor plate formation [GO:0021508]; glial cell migration [GO:0008347]; motor neuron axon guidance [GO:0008045]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357]; Schwann cell development [GO:0014044]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; ventral spinal cord interneuron differentiation [GO:0021514] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0008045; GO:0008347; GO:0014044; GO:0021508; GO:0021514; GO:0021529; GO:0021530; GO:0030154; GO:0031018; GO:0033504; GO:0045893 22780 FUN_016374 145 160 100 152 117 ptg000011l:2419022-2420101 P42586 2.68e-41 Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B) Mus musculus (Mouse) astrocyte differentiation [GO:0048708]; cell development [GO:0048468]; cell differentiation [GO:0030154]; digestive tract development [GO:0048565]; endocrine pancreas development [GO:0031018]; negative regulation of neuron differentiation [GO:0045665]; nervous system development [GO:0007399]; neuroendocrine cell differentiation [GO:0061101]; neuron differentiation [GO:0030182]; neuron fate specification [GO:0048665]; oligodendrocyte development [GO:0014003]; oligodendrocyte differentiation [GO:0048709]; optic nerve development [GO:0021554]; pancreatic A cell fate commitment [GO:0003326]; pancreatic PP cell fate commitment [GO:0003329]; positive regulation of epithelial cell differentiation [GO:0030858]; positive regulation of gene expression [GO:0010628]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of oligodendrocyte differentiation [GO:0048714]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; response to glucose [GO:0009749]; response to progesterone [GO:0032570]; smoothened signaling pathway [GO:0007224]; spinal cord motor neuron differentiation [GO:0021522]; spinal cord oligodendrocyte cell differentiation [GO:0021529]; spinal cord oligodendrocyte cell fate specification [GO:0021530]; type B pancreatic cell development [GO:0003323]; type B pancreatic cell differentiation [GO:0003309]; type B pancreatic cell fate commitment [GO:0003327]; ventral spinal cord interneuron fate determination [GO:0060580] GO:0000978; GO:0000981; GO:0000987; GO:0001228; GO:0003309; GO:0003323; GO:0003326; GO:0003327; GO:0003329; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007224; GO:0007399; GO:0009749; GO:0010628; GO:0014003; GO:0021522; GO:0021529; GO:0021530; GO:0021554; GO:0030154; GO:0030182; GO:0030858; GO:0031018; GO:0032570; GO:0043565; GO:0045665; GO:0045666; GO:0045944; GO:0048468; GO:0048565; GO:0048665; GO:0048708; GO:0048709; GO:0048714; GO:0060580; GO:0061101 22781 FUN_016377 11 0 16 54 29 NA NA NA NA NA NA NA 22782 FUN_016376 374 182 295 293 96 NA NA NA NA NA NA NA 22783 FUN_015632 1 2 16 1 19 NA NA NA NA NA NA NA 22784 FUN_015636 3 0 2 7 8 NA NA NA NA NA NA NA 22785 FUN_013327 5084 3622 1948 4006 3335 NA NA NA NA NA NA NA 22786 FUN_026348 760 2017 1150 361 487 NA NA NA NA NA NA NA 22787 FUN_026343 122 0 13 0 0 NA NA NA NA NA NA NA 22788 FUN_026342 30 0 7 0 0 NA NA NA NA NA NA NA 22789 FUN_026341 36 0 3 0 0 NA NA NA NA NA NA NA 22790 FUN_026340 38 0 8 0 0 NA NA NA NA NA NA NA 22791 FUN_026347 71 0 0 49 7 ptg000020l:7796384-7798318 Q9CZR2 8.57e-66 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 22792 FUN_026346 0 0 0 0 10 NA NA NA NA NA NA NA 22793 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 6.24e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22794 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 6.24e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22795 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 6.24e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22796 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 6.24e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22797 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 6.24e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22798 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 6.24e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22799 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 4.72e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22800 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 4.72e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22801 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 4.72e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22802 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 4.72e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22803 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 4.72e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22804 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 4.72e-41 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22805 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.05e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22806 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.05e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22807 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.05e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22808 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.05e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22809 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.05e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22810 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 2.06e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22811 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 2.06e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22812 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 2.06e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22813 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 2.06e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22814 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 2.06e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22815 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 8.21e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22816 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 8.21e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22817 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 8.21e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22818 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 8.21e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22819 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 8.21e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22820 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.98e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22821 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.98e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22822 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.98e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22823 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.98e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22824 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.37e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22825 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.37e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22826 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.37e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22827 FUN_026345 731 177 170 140 112 ptg000020l:7774777-7786803 P10079 1.37e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22828 FUN_026344 211 0 20 0 0 NA NA NA NA NA NA NA 22829 FUN_025698 1864 1412 1287 1741 2056 NA NA NA NA NA NA NA 22830 FUN_025699 948 907 765 834 693 NA NA NA NA NA NA NA 22831 FUN_025690 3418 1996 1892 5368 4003 NA NA NA NA NA NA NA 22832 FUN_025691 339 182 165 234 268 ptg000019l:5782463-5787758 Q0WW17 9.15e-75 Protein REDUCED WALL ACETYLATION 2 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]; plant-type secondary cell wall biogenesis [GO:0009834]; polysaccharide metabolic process [GO:0005976]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000138; GO:0000139; GO:0005783; GO:0005789; GO:0005794; GO:0005975; GO:0005976; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:0050832; GO:1990937 22833 FUN_025691 339 182 165 234 268 ptg000019l:5782463-5787758 Q0WW17 1.11e-21 Protein REDUCED WALL ACETYLATION 2 (EC 2.3.1.-) Arabidopsis thaliana (Mouse-ear cress) carbohydrate metabolic process [GO:0005975]; defense response to fungus [GO:0050832]; plant-type secondary cell wall biogenesis [GO:0009834]; polysaccharide metabolic process [GO:0005976]; xylan acetylation [GO:1990937]; xylan biosynthetic process [GO:0045492]; xylan metabolic process [GO:0045491]; xyloglucan metabolic process [GO:0010411] GO:0000138; GO:0000139; GO:0005783; GO:0005789; GO:0005794; GO:0005975; GO:0005976; GO:0009834; GO:0010411; GO:0016407; GO:0016491; GO:0045491; GO:0045492; GO:0050832; GO:1990937 22834 FUN_025692 1854 974 1076 1301 1071 NA NA NA NA NA NA NA 22835 FUN_025693 2044 1169 1217 1776 1831 NA NA NA NA NA NA NA 22836 FUN_025694 96 0 12 100 9 NA NA NA NA NA NA NA 22837 FUN_025695 100 153 94 146 216 NA NA NA NA NA NA NA 22838 FUN_025696 322 476 175 334 268 NA NA NA NA NA NA NA 22839 FUN_025697 0 0 15 6 37 NA NA NA NA NA NA NA 22840 FUN_017778 243 230 213 283 345 NA NA NA NA NA NA NA 22841 FUN_017779 12 0 0 41 14 NA NA NA NA NA NA NA 22842 FUN_017776 390 517 354 341 549 ptg000012l:317176-318973 A4FUD4 7.42e-58 Peroxisome assembly protein 12 (Peroxin-12) Bos taurus (Bovine) peroxisome organization [GO:0007031]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein monoubiquitination [GO:0006513] GO:0004842; GO:0005778; GO:0006513; GO:0007031; GO:0008022; GO:0008270; GO:0016558; GO:0016562; GO:1990429; GO:1990757 22843 FUN_017777 5045 4600 3159 3762 1789 NA NA NA NA NA NA NA 22844 FUN_017774 1350 1109 612 896 1043 NA NA NA NA NA NA NA 22845 FUN_017775 1075 1309 716 734 860 ptg000012l:315645-316867 A9ULE9 1.56e-43 DnaJ homolog subfamily C member 22 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016020 22846 FUN_017772 687 1044 631 975 1204 NA NA NA NA NA NA NA 22847 FUN_017773 3684 3759 2758 5631 5766 ptg000012l:291752-301862 Q6RVG2 6.59e-31 Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na+-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3) Rattus norvegicus (Rat) basolateral protein secretion [GO:0110010]; bicarbonate transport [GO:0015701]; chloride transmembrane transport [GO:1902476]; ion homeostasis [GO:0050801]; modulation of chemical synaptic transmission [GO:0050804]; positive regulation of synaptic vesicle exocytosis [GO:2000302]; regulation of intracellular pH [GO:0051453]; regulation of membrane potential [GO:0042391]; sodium ion transmembrane transport [GO:0035725]; transmembrane transport [GO:0055085] GO:0005886; GO:0008021; GO:0008510; GO:0015081; GO:0015106; GO:0015108; GO:0015701; GO:0016020; GO:0016323; GO:0016324; GO:0022857; GO:0030425; GO:0030672; GO:0032279; GO:0032280; GO:0032809; GO:0035725; GO:0042391; GO:0042734; GO:0042802; GO:0043005; GO:0043195; GO:0043679; GO:0050801; GO:0050804; GO:0051453; GO:0055085; GO:0097386; GO:0097457; GO:0098793; GO:0098978; GO:0110010; GO:0140892; GO:1902476; GO:2000302 22848 FUN_017770 21 0 0 0 8 NA NA NA NA NA NA NA 22849 FUN_017771 1089 521 55 388 1700 NA NA NA NA NA NA NA 22850 FUN_028418 10 0 0 0 39 NA NA NA NA NA NA NA 22851 FUN_023449 2603 1581 1547 2643 2220 NA NA NA NA NA NA NA 22852 FUN_023448 73 57 40 196 55 NA NA NA NA NA NA NA 22853 FUN_028411 0 0 19 0 17 NA NA NA NA NA NA NA 22854 FUN_023446 183 54 81 96 143 ptg000017l:7596081-7602725 Q925H0 1.96e-21 Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Brain sodium channel 1) (BNC1) (BNaC1) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to xenobiotic stimulus [GO:0071466]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; negative regulation of apoptotic process [GO:0043066]; phototransduction [GO:0007602]; positive regulation of cation channel activity [GO:2001259]; positive regulation of synapse assembly [GO:0051965]; protein localization to synapse [GO:0035418]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback [GO:0003026]; regulation of vasoconstriction [GO:0019229]; response to acidic pH [GO:0010447]; response to mechanical stimulus [GO:0009612]; sensory perception of sound [GO:0007605]; sensory perception of sour taste [GO:0050915]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814]; synapse assembly [GO:0007416] GO:0003026; GO:0005216; GO:0005248; GO:0005261; GO:0005886; GO:0006812; GO:0006814; GO:0007416; GO:0007602; GO:0007605; GO:0009612; GO:0010447; GO:0015280; GO:0016020; GO:0019229; GO:0022839; GO:0034220; GO:0034765; GO:0035418; GO:0035725; GO:0042391; GO:0043005; GO:0043025; GO:0043066; GO:0043197; GO:0045202; GO:0050915; GO:0050974; GO:0051649; GO:0051965; GO:0071466; GO:0071468; GO:2001259 22855 FUN_028413 18 0 0 962 69 NA NA NA NA NA NA NA 22856 FUN_028415 19 25 9 26 0 NA NA NA NA NA NA NA 22857 FUN_023442 7612 7396 4181 3099 3367 NA NA NA NA NA NA NA 22858 FUN_023441 27 64 6 61 48 ptg000017l:7548246-7559766 Q9NBX4 6.81e-33 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 22859 FUN_023440 396 480 284 295 935 NA NA NA NA NA NA NA 22860 FUN_022318 203 198 126 181 45 NA NA NA NA NA NA NA 22861 FUN_022319 570 414 289 885 454 NA NA NA NA NA NA NA 22862 FUN_022314 449 559 386 475 828 ptg000016l:7473530-7479268 Q9UJT9 8.73e-97 F-box/LRR-repeat protein 7 (F-box and leucine-rich repeat protein 7) (F-box protein FBL6/FBL7) Homo sapiens (Human) cell division [GO:0051301]; G2/M transition of mitotic cell cycle [GO:0000086]; mitotic cell cycle [GO:0000278]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000086; GO:0000151; GO:0000209; GO:0000278; GO:0005813; GO:0005829; GO:0006511; GO:0016567; GO:0019005; GO:0031146; GO:0051301 22863 FUN_022315 5396 5441 2971 1589 2249 ptg000016l:7484597-7488160 Q8VIG3 4.56e-68 Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Mus musculus (Mouse) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0007286; GO:0031514; GO:0035082; GO:0036126; GO:0051321; GO:0072687 22864 FUN_022316 685 220 463 500 258 NA NA NA NA NA NA NA 22865 FUN_022317 7 0 0 43 26 NA NA NA NA NA NA NA 22866 FUN_022310 3332 3854 1128 2953 2105 NA NA NA NA NA NA NA 22867 FUN_022311 1218 479 755 1232 768 NA NA NA NA NA NA NA 22868 FUN_022313 286 174 119 176 121 NA NA NA NA NA NA NA 22869 FUN_024875 0 0 9 0 0 NA NA NA NA NA NA NA 22870 FUN_024873 5296 5536 2932 4262 3174 NA NA NA NA NA NA NA 22871 FUN_024872 712 407 195 409 500 ptg000018l:11927862-11942211 Q17RP2 7.91e-27 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 22872 FUN_024872 712 407 195 409 500 ptg000018l:11927862-11942211 Q17RP2 7.91e-27 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 22873 FUN_024872 712 407 195 409 500 ptg000018l:11927862-11942211 Q17RP2 7.91e-27 Tigger transposable element-derived protein 6 Homo sapiens (Human) NA GO:0003677; GO:0005634 22874 FUN_024871 581 296 268 316 322 NA NA NA NA NA NA NA 22875 FUN_024870 24 0 80 32 105 NA NA NA NA NA NA NA 22876 FUN_024878 18 25 46 62 69 ptg000018l:12003993-12008269 Q9U6Y5 1.53e-36 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 22877 FUN_024878 18 25 46 62 69 ptg000018l:12003993-12008269 Q9U6Y5 1.04e-34 GFP-like fluorescent chromoprotein FP506 (zFP506) Zoanthus sp. (Green polyp) bioluminescence [GO:0008218] GO:0008218 22878 FUN_043148 16407 15087 15035 10790 4710 NA NA NA NA NA NA NA 22879 FUN_022789 0 100 0 0 134 ptg000016l:12934749-12935600 P51955 2.03e-35 Serine/threonine-protein kinase Nek2 (EC 2.7.11.1) (HSPK 21) (Never in mitosis A-related kinase 2) (NimA-related protein kinase 2) (NimA-like protein kinase 1) Homo sapiens (Human) blastocyst development [GO:0001824]; cell division [GO:0051301]; centrosome separation [GO:0051299]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly [GO:0090307]; negative regulation of centriole-centriole cohesion [GO:1903126]; negative regulation of DNA binding [GO:0043392]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of mitotic centrosome separation [GO:0046602]; regulation of mitotic nuclear division [GO:0007088]; spindle assembly [GO:0051225] GO:0000070; GO:0000278; GO:0000776; GO:0000794; GO:0000922; GO:0001824; GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005874; GO:0006468; GO:0007059; GO:0007088; GO:0019903; GO:0030496; GO:0032212; GO:0032991; GO:0043392; GO:0046602; GO:0046777; GO:0046872; GO:0051225; GO:0051299; GO:0051301; GO:0051321; GO:0051973; GO:0051988; GO:0090307; GO:0106310; GO:1903126; GO:1904355 22880 FUN_043149 547 439 234 461 837 NA NA NA NA NA NA NA 22881 FUN_009105 65 27 46 0 64 NA NA NA NA NA NA NA 22882 FUN_009108 42 16 0 19 0 NA NA NA NA NA NA NA 22883 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 2.07e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22884 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 2.01e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22885 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 2.01e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22886 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 1.12e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22887 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 3.02e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22888 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 4.31e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22889 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 1.2e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22890 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 4.75e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22891 FUN_009109 181 132 175 21 88 ptg000004l:2793140-2805657 Q96AY4 2.28e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 22892 FUN_019635 1 0 8 3 1 NA NA NA NA NA NA NA 22893 FUN_019631 32 0 13 15 0 NA NA NA NA NA NA NA 22894 FUN_019633 68 89 30 24 250 NA NA NA NA NA NA NA 22895 FUN_019632 0 21 6 0 51 NA NA NA NA NA NA NA 22896 FUN_011460 0 0 0 11 0 NA NA NA NA NA NA NA 22897 FUN_043141 4436 2956 927 5162 1933 ptg000047l:4505620-4509134 B8EIZ7 9.43e-79 NA NA NA NA 22898 FUN_043141 4436 2956 927 5162 1933 ptg000047l:4505620-4509134 B8EIZ7 9.38e-21 NA NA NA NA 22899 FUN_043144 28094 34818 14865 31106 27096 ptg000047l:4534548-4540456 Q9W5R8 1.04e-22 60S ribosomal protein L5 Drosophila melanogaster (Fruit fly) cytoplasmic translation [GO:0002181]; ribosomal large subunit assembly [GO:0000027] GO:0000027; GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0008097; GO:0022625; GO:0022626 22900 FUN_043145 947 581 393 876 601 NA NA NA NA NA NA NA 22901 FUN_024253 42 8 0 43 0 ptg000018l:3941803-4033437 E9Q5R7 2.97e-46 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 22902 FUN_024252 45 0 0 0 159 ptg000018l:3933096-3935709 Q9Y239 4.58e-23 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0006952; GO:0006954; GO:0007165; GO:0007249; GO:0007254; GO:0008656; GO:0009595; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042834; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 22903 FUN_024251 86 0 16 3 374 ptg000018l:3922680-3931483 Q7RTR2 6.73e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22904 FUN_024257 29 88 25 51 31 ptg000018l:4070070-4074809 Q5DU56 2.59e-39 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22905 FUN_024256 0 27 49 0 35 NA NA NA NA NA NA NA 22906 FUN_024254 32 6 0 14 5 ptg000018l:4041685-4045953 Q8K3Z0 3.55e-28 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 22907 FUN_024259 21 140 127 221 40 NA NA NA NA NA NA NA 22908 FUN_024258 0 90 33 20 48 NA NA NA NA NA NA NA 22909 FUN_040789 0 3 0 0 15 NA NA NA NA NA NA NA 22910 FUN_030127 0 7 0 0 59 NA NA NA NA NA NA NA 22911 FUN_030129 145 167 19 398 142 NA NA NA NA NA NA NA 22912 FUN_038357 5 0 48 268 0 NA NA NA NA NA NA NA 22913 FUN_038355 111 22 166 294 265 NA NA NA NA NA NA NA 22914 FUN_038354 159 201 222 544 251 ptg000027l:6125847-6132442 A2A259 3.3e-44 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to pH [GO:0071467]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0034703; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051262; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071467; GO:0071468; GO:0071805; GO:0097730; GO:0098662 22915 FUN_038353 88 3 147 90 227 NA NA NA NA NA NA NA 22916 FUN_038352 37 21 64 45 117 NA NA NA NA NA NA NA 22917 FUN_038351 159 117 61 462 271 ptg000027l:6084548-6100008 Q4GZT3 2.09e-40 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 22918 FUN_038350 0 0 0 11 52 NA NA NA NA NA NA NA 22919 FUN_038359 26 98 99 175 142 NA NA NA NA NA NA NA 22920 FUN_038358 139 124 272 835 285 ptg000027l:6185931-6192010 Q4GZT3 1.06e-42 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 22921 FUN_039405 123 52 99 71 76 NA NA NA NA NA NA NA 22922 FUN_039406 718 140 164 743 668 ptg000029c:1434319-1441755 Q7RTR2 3.05e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22923 FUN_039406 718 140 164 743 668 ptg000029c:1434319-1441755 Q7RTR2 5.95e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22924 FUN_039406 718 140 164 743 668 ptg000029c:1434319-1441755 Q7RTR2 2.73e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22925 FUN_039406 718 140 164 743 668 ptg000029c:1434319-1441755 Q7RTR2 1.29e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22926 FUN_039406 718 140 164 743 668 ptg000029c:1434319-1441755 Q7RTR2 2.37e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22927 FUN_039406 718 140 164 743 668 ptg000029c:1434319-1441755 Q7RTR2 6.78e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22928 FUN_039407 87 0 0 0 0 NA NA NA NA NA NA NA 22929 FUN_039400 11 4 1 1 1 NA NA NA NA NA NA NA 22930 FUN_039401 38 35 0 8 53 NA NA NA NA NA NA NA 22931 FUN_039402 121 95 43 27 113 ptg000029c:1408782-1412464 Q63E45 2.66e-43 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain ZK / E33L) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 22932 FUN_039408 311 0 0 36 0 NA NA NA NA NA NA NA 22933 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 2.87e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22934 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 5.64e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22935 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 7.08e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22936 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 3.46e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22937 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 1.05e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22938 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 7.61e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22939 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 5.06e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22940 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 2.01e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22941 FUN_039409 429 30 232 62 234 ptg000029c:1490818-1551394 Q7RTR2 1.96e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 22942 FUN_015198 433 229 56 318 326 ptg000009l:7398725-7400660 Q96CG8 2.38e-33 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22943 FUN_015199 0 0 0 293 95 ptg000009l:7413390-7414671 Q96CG8 3.2e-35 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22944 FUN_015194 107 74 55 424 97 ptg000009l:7334142-7357709 Q96CG8 4.18e-35 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22945 FUN_015194 107 74 55 424 97 ptg000009l:7334142-7357709 Q96CG8 4.82e-32 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22946 FUN_015194 107 74 55 424 97 ptg000009l:7334142-7357709 Q96CG8 2.42e-30 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22947 FUN_015195 1182 0 16 386 236 ptg000009l:7365089-7365755 Q96CG8 2.47e-32 Collagen triple helix repeat-containing protein 1 Homo sapiens (Human) cell migration [GO:0016477]; cochlea morphogenesis [GO:0090103]; establishment of planar polarity involved in neural tube closure [GO:0090177]; inner ear receptor cell stereocilium organization [GO:0060122]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; ossification involved in bone remodeling [GO:0043932]; osteoblast differentiation [GO:0001649]; osteoblast proliferation [GO:0033687]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of protein binding [GO:0032092]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0001649; GO:0005109; GO:0005576; GO:0005581; GO:0005615; GO:0016477; GO:0016528; GO:0017147; GO:0032092; GO:0033687; GO:0033690; GO:0043932; GO:0045669; GO:0060071; GO:0060122; GO:0062023; GO:0090090; GO:0090103; GO:0090177 22948 FUN_015196 17 4 61 170 93 NA NA NA NA NA NA NA 22949 FUN_015190 133 77 25 144 92 NA NA NA NA NA NA NA 22950 FUN_015191 2589 1794 1138 3204 1885 NA NA NA NA NA NA NA 22951 FUN_015192 1676 1125 776 1012 1143 NA NA NA NA NA NA NA 22952 FUN_015193 2762 1475 1193 2386 2777 NA NA NA NA NA NA NA 22953 FUN_019034 0 0 7 0 0 NA NA NA NA NA NA NA 22954 FUN_005858 3034 1872 995 2943 2349 NA NA NA NA NA NA NA 22955 FUN_019032 0 22 27 140 0 NA NA NA NA NA NA NA 22956 FUN_027757 42 0 0 0 0 NA NA NA NA NA NA NA 22957 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.35e-105 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22958 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.34e-102 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22959 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.14e-101 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22960 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.46e-100 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22961 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.18e-99 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22962 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 3.92e-98 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22963 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 5.47e-97 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22964 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 3.01e-93 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22965 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 4.11e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22966 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 4.59e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22967 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 3.92e-76 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22968 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 7.8e-65 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22969 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 5.15e-64 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22970 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 7.28e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22971 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.73e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22972 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.12e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22973 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 7.09e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22974 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 7.41e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22975 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 9.67e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22976 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 7.33e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22977 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 5.81e-55 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22978 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 4.2e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22979 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.07e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22980 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 4.34e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22981 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.87e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22982 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 6.42e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22983 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.78e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22984 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.97e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22985 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.6e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22986 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 1.81e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22987 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 5.19e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22988 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.67e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22989 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 4.96e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22990 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 5.64e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22991 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22992 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.67e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22993 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.69e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22994 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 6.67e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22995 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 2.7e-27 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22996 FUN_027756 662 76 99 576 672 ptg000021l:10227826-10293389 P10079 6.04e-27 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 22997 FUN_027755 330 44 66 886 211 ptg000021l:10190215-10226205 Q9QYP1 6.52e-32 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 22998 FUN_027755 330 44 66 886 211 ptg000021l:10190215-10226205 Q9QYP1 1.88e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 22999 FUN_027755 330 44 66 886 211 ptg000021l:10190215-10226205 Q9QYP1 6.55e-27 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23000 FUN_027755 330 44 66 886 211 ptg000021l:10190215-10226205 Q9QYP1 3.37e-26 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23001 FUN_027755 330 44 66 886 211 ptg000021l:10190215-10226205 Q9QYP1 7.53e-23 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23002 FUN_027755 330 44 66 886 211 ptg000021l:10190215-10226205 Q9QYP1 1.76e-22 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23003 FUN_027753 0 0 12 134 37 NA NA NA NA NA NA NA 23004 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 5.04e-108 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23005 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.53e-105 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23006 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.36e-103 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23007 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 9.37e-103 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23008 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 6.14e-101 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23009 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.29e-96 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23010 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.99e-96 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23011 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.51e-90 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23012 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.44e-88 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23013 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 6.97e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23014 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 3.81e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23015 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 8.57e-65 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23016 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 9.64e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23017 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 4.79e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23018 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 7.14e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23019 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 5.67e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23020 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.28e-59 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23021 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.53e-59 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23022 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 8.33e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23023 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 2.97e-55 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23024 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 8.48e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23025 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 2.76e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23026 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 5.85e-35 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23027 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 2.97e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23028 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 2.21e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23029 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 7.34e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23030 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 7.92e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23031 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 1.66e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23032 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 3.13e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23033 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 3.33e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23034 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 8.04e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23035 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 2.51e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23036 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 3.72e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23037 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 4.12e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23038 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 4.23e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23039 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 3.89e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23040 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 6.47e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23041 FUN_027752 358 25 241 1802 555 ptg000021l:10108095-10171257 P10079 3.47e-27 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 23042 FUN_027751 127 94 892 751 776 ptg000021l:10069597-10106475 Q8VI56 1.33e-30 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23043 FUN_027751 127 94 892 751 776 ptg000021l:10069597-10106475 Q8VI56 1.79e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23044 FUN_027751 127 94 892 751 776 ptg000021l:10069597-10106475 Q8VI56 9.56e-27 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23045 FUN_027751 127 94 892 751 776 ptg000021l:10069597-10106475 Q8VI56 5.43e-26 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23046 FUN_027751 127 94 892 751 776 ptg000021l:10069597-10106475 Q8VI56 1.18e-22 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23047 FUN_027751 127 94 892 751 776 ptg000021l:10069597-10106475 Q8VI56 1.88e-22 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 23048 FUN_027750 2 2 17 179 47 NA NA NA NA NA NA NA 23049 FUN_027758 31 0 0 7 0 NA NA NA NA NA NA NA 23050 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 2.72e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23051 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 1.63e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23052 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 7.22e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23053 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 1.68e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23054 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 1.83e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23055 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 1.58e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23056 FUN_018353 163 0 141 284 76 ptg000012l:8262853-8282187 Q96AY4 1.7e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23057 FUN_036607 86 145 98 2 361 NA NA NA NA NA NA NA 23058 FUN_031653 2520 1502 848 1033 773 NA NA NA NA NA NA NA 23059 FUN_036604 0 0 9 0 0 NA NA NA NA NA NA NA 23060 FUN_031655 0 2 0 26 0 NA NA NA NA NA NA NA 23061 FUN_031654 112 7 16 0 171 ptg000023l:24003278-24020445 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23062 FUN_031654 112 7 16 0 171 ptg000023l:24003278-24020445 Q9NZJ4 2.99e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23063 FUN_031654 112 7 16 0 171 ptg000023l:24003278-24020445 Q9NZJ4 7.14e-51 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23064 FUN_031654 112 7 16 0 171 ptg000023l:24003278-24020445 Q9NZJ4 3.85e-22 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23065 FUN_031658 522 266 233 359 403 ptg000023l:24057582-24085701 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23066 FUN_031658 522 266 233 359 403 ptg000023l:24057582-24085701 Q9NZJ4 2.52e-48 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23067 FUN_031658 522 266 233 359 403 ptg000023l:24057582-24085701 Q9NZJ4 4.88e-48 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23068 FUN_031658 522 266 233 359 403 ptg000023l:24057582-24085701 Q9NZJ4 3.76e-22 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23069 FUN_031200 87 85 25 26 41 NA NA NA NA NA NA NA 23070 FUN_036609 0 0 351 93 1 NA NA NA NA NA NA NA 23071 FUN_036608 55 93 78 0 269 NA NA NA NA NA NA NA 23072 FUN_037555 3482 2850 2089 5659 3700 NA NA NA NA NA NA NA 23073 FUN_037556 334 307 208 267 209 ptg000026l:11787288-11792351 P57789 2.76e-23 Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit) Homo sapiens (Human) memory [GO:0007613]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165]; stabilization of membrane potential [GO:0030322] GO:0005267; GO:0005886; GO:0007165; GO:0007613; GO:0015271; GO:0022841; GO:0030322; GO:0034765; GO:0071805 23074 FUN_037557 405 785 552 343 457 ptg000026l:11795903-11802918 Q9BUZ4 1.14e-21 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 23075 FUN_037550 0 84 26 0 5 NA NA NA NA NA NA NA 23076 FUN_037551 0 4 0 361 0 NA NA NA NA NA NA NA 23077 FUN_037552 43 49 15 29 64 NA NA NA NA NA NA NA 23078 FUN_037553 3938 2368 1862 3572 2794 ptg000026l:11714566-11730978 Q9WTK5 6.98e-25 Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit] Mus musculus (Mouse) extracellular matrix organization [GO:0030198]; follicular dendritic cell differentiation [GO:0002268]; germinal center formation [GO:0002467]; lymph node development [GO:0048535]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357]; rhythmic process [GO:0048511]; spleen development [GO:0048536] GO:0000978; GO:0000981; GO:0001228; GO:0002268; GO:0002467; GO:0005634; GO:0005737; GO:0005829; GO:0006355; GO:0006357; GO:0030198; GO:0033257; GO:0038061; GO:0045944; GO:0048511; GO:0048535; GO:0048536; GO:0071159; GO:1990837 23079 FUN_036254 10044 7356 4435 5526 2470 ptg000025l:17172838-17187691 Q9UJX0 4.94e-93 Oxidative stress-induced growth inhibitor 1 (Bone marrow stromal cell-derived growth inhibitor) (BMSC-derived growth inhibitor) (Ovary, kidney and liver protein 38) (huOKL38) (Pregnancy-induced growth inhibitor OKL38) Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of cell growth [GO:0030308]; regulation of apoptotic process [GO:0042981]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0008083; GO:0030154; GO:0030308; GO:0030334; GO:0042127; GO:0042981 23080 FUN_037558 11 2762 41 41 34 NA NA NA NA NA NA NA 23081 FUN_037559 189 233 55 44 161 ptg000026l:11808339-11816717 Q9BUZ4 6.56e-23 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 23082 FUN_036255 532 539 236 553 446 NA NA NA NA NA NA NA 23083 FUN_036256 142 94 78 147 73 NA NA NA NA NA NA NA 23084 FUN_036257 168 168 176 197 136 NA NA NA NA NA NA NA 23085 FUN_031389 0 0 0 0 28 NA NA NA NA NA NA NA 23086 FUN_031388 8 67 9 3 24 NA NA NA NA NA NA NA 23087 FUN_031382 824 33 0 671 402 ptg000023l:20399362-20406840 Q7RTR2 3.01e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23088 FUN_031382 824 33 0 671 402 ptg000023l:20399362-20406840 Q7RTR2 5.5e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23089 FUN_031382 824 33 0 671 402 ptg000023l:20399362-20406840 Q7RTR2 2.68e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23090 FUN_031382 824 33 0 671 402 ptg000023l:20399362-20406840 Q7RTR2 2.86e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23091 FUN_031382 824 33 0 671 402 ptg000023l:20399362-20406840 Q7RTR2 1.38e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23092 FUN_031382 824 33 0 671 402 ptg000023l:20399362-20406840 Q7RTR2 2.33e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23093 FUN_031380 0 0 0 0 15 NA NA NA NA NA NA NA 23094 FUN_031387 199 141 174 46 205 NA NA NA NA NA NA NA 23095 FUN_039355 89 105 0 101 59 NA NA NA NA NA NA NA 23096 FUN_026805 26 38 20 14 42 NA NA NA NA NA NA NA 23097 FUN_026800 0 17 25 17 38 NA NA NA NA NA NA NA 23098 FUN_026801 0 0 0 0 64 NA NA NA NA NA NA NA 23099 FUN_026803 0 0 0 28 13 ptg000020l:13653302-13657149 Q94K49 1.89e-32 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 23100 FUN_026808 0 0 10 7 12 NA NA NA NA NA NA NA 23101 FUN_018352 725 654 172 461 550 NA NA NA NA NA NA NA 23102 FUN_024900 338 277 289 376 359 NA NA NA NA NA NA NA 23103 FUN_037786 0 0 0 12 12 NA NA NA NA NA NA NA 23104 FUN_001258 150 230 71 495 352 NA NA NA NA NA NA NA 23105 FUN_001259 87 84 32 67 44 NA NA NA NA NA NA NA 23106 FUN_001256 38 43 46 46 73 NA NA NA NA NA NA NA 23107 FUN_001257 34 3 30 30 26 ntLink_6:10382783-10383815 Q804X9 2.93e-43 Melanopsin-A (Opsin-4A) Gadus morhua (Atlantic cod) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 23108 FUN_001254 0 0 16 0 0 NA NA NA NA NA NA NA 23109 FUN_001255 1334 1037 1053 943 972 NA NA NA NA NA NA NA 23110 FUN_001252 2269 1787 1237 1607 1548 NA NA NA NA NA NA NA 23111 FUN_001250 113 181 172 305 249 NA NA NA NA NA NA NA 23112 FUN_001251 1448 675 232 1019 576 NA NA NA NA NA NA NA 23113 FUN_025869 520 763 76 263 738 ptg000020l:1458795-1467810 Q7RTR2 7.67e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23114 FUN_025866 45 5 57 68 38 ptg000020l:1433584-1443382 Q7RTR2 2.54e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 23115 FUN_025864 340 169 219 464 366 ptg000020l:1423894-1427670 E9Q5R7 3.55e-40 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 23116 FUN_025864 340 169 219 464 366 ptg000020l:1423894-1427670 E9Q5R7 3.55e-40 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 23117 FUN_025863 0 15 17 0 78 NA NA NA NA NA NA NA 23118 FUN_025862 3 0 7 6 0 NA NA NA NA NA NA NA 23119 FUN_025861 0 16 19 8 7 NA NA NA NA NA NA NA 23120 FUN_025860 413 559 219 853 297 ptg000020l:1378727-1394908 C6FG12 2.55e-29 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 23121 FUN_018225 53 0 57 261 246 ptg000012l:6252969-6259341 Q9Y6N7 7.25e-22 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 23122 FUN_007942 0 0 0 13 17 NA NA NA NA NA NA NA 23123 FUN_018226 1364 876 241 935 383 NA NA NA NA NA NA NA 23124 FUN_007944 482 806 570 897 888 ptg000002l:6413058-6414078 Q6DC77 7.29e-53 Membrane progestin receptor gamma-B (mPR gamma-B) (Progestin and adipoQ receptor family member V-B) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 23125 FUN_007945 588 458 405 288 1978 ptg000002l:6415908-6418564 P36410 1.69e-33 Ras-related protein Rab-14 (Rab4-like GTPase) Dictyostelium discoideum (Social amoeba) contractile vacuole organization [GO:0033298]; defense response to bacterium [GO:0042742]; endocytic recycling [GO:0032456]; Golgi to endosome transport [GO:0006895]; intracellular protein transport [GO:0006886]; phagolysosome assembly involved in apoptotic cell clearance [GO:0090387]; regulation of endosomal vesicle fusion [GO:1905364]; regulation of pinocytosis [GO:0048548]; response to osmotic stress [GO:0006970] GO:0003924; GO:0005525; GO:0005764; GO:0005765; GO:0005769; GO:0005802; GO:0005811; GO:0005829; GO:0006886; GO:0006895; GO:0006970; GO:0012505; GO:0031164; GO:0032456; GO:0033298; GO:0042742; GO:0045335; GO:0048548; GO:0055037; GO:0062160; GO:0090387; GO:0140220; GO:1905364 23126 FUN_007947 337 300 235 272 239 NA NA NA NA NA NA NA 23127 FUN_007948 1612 624 553 975 516 NA NA NA NA NA NA NA 23128 FUN_007949 3843 5209 2834 2999 2158 NA NA NA NA NA NA NA 23129 FUN_018229 272 112 76 985 210 NA NA NA NA NA NA NA 23130 FUN_018228 13 25 52 0 18 NA NA NA NA NA NA NA 23131 FUN_034148 242 87 134 50 63 NA NA NA NA NA NA NA 23132 FUN_034149 1345 801 633 711 741 NA NA NA NA NA NA NA 23133 FUN_034146 122 35 7 31 40 NA NA NA NA NA NA NA 23134 FUN_034147 0 0 0 8 0 NA NA NA NA NA NA NA 23135 FUN_034144 2033 792 996 1397 901 NA NA NA NA NA NA NA 23136 FUN_034145 63 41 36 52 99 NA NA NA NA NA NA NA 23137 FUN_034142 838 174 399 392 8 NA NA NA NA NA NA NA 23138 FUN_034143 13240 9261 7701 12502 8259 ptg000024l:5307279-5317542 Q03168 3.99e-22 Lysosomal aspartic protease (EC 3.4.23.-) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) proteolysis [GO:0006508] GO:0004190; GO:0005764; GO:0006508 23139 FUN_034140 80 76 47 28 25 NA NA NA NA NA NA NA 23140 FUN_019178 13 0 5 2 24 NA NA NA NA NA NA NA 23141 FUN_019172 14 1 43 1 225 ptg000012l:18041450-18041879 P84239 8.83e-89 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 23142 FUN_019170 214 1 0 0 0 NA NA NA NA NA NA NA 23143 FUN_019171 27 1 95 1 128 ptg000012l:18026494-18026806 Q6LAF1 1.03e-53 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 23144 FUN_019176 16 0 0 0 0 NA NA NA NA NA NA NA 23145 FUN_019177 21 25 60 2 148 NA NA NA NA NA NA NA 23146 FUN_044018 11 0 6 0 0 NA NA NA NA NA NA NA 23147 FUN_043470 922 29 16 454 5 NA NA NA NA NA NA NA 23148 FUN_043471 951 70 74 498 8 NA NA NA NA NA NA NA 23149 FUN_043472 865 0 21 248 0 NA NA NA NA NA NA NA 23150 FUN_043473 701 29 3 104 0 NA NA NA NA NA NA NA 23151 FUN_043474 635 170 75 117 130 NA NA NA NA NA NA NA 23152 FUN_043475 2297 289 123 1298 520 NA NA NA NA NA NA NA 23153 FUN_043476 1105 282 248 579 239 NA NA NA NA NA NA NA 23154 FUN_043477 6092 20 23 2210 104 NA NA NA NA NA NA NA 23155 FUN_043478 108 18 2 5 2 NA NA NA NA NA NA NA 23156 FUN_043479 1451 1371 810 786 815 NA NA NA NA NA NA NA 23157 FUN_030248 3 0 2 0 17 ptg000023l:10454475-10455238 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 23158 FUN_030242 2 0 3 0 14 ptg000023l:10442319-10443082 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 23159 FUN_030244 1 0 1 0 6 ptg000023l:10446371-10447134 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 23160 FUN_012389 85 111 28 91 130 NA NA NA NA NA NA NA 23161 FUN_029989 109 8 70 2 101 NA NA NA NA NA NA NA 23162 FUN_002235 0 0 1 0 24 NA NA NA NA NA NA NA 23163 FUN_002237 0 0 0 0 6 NA NA NA NA NA NA NA 23164 FUN_002231 8 0 15 0 87 ntLink_6:22681054-22682652 Q6LAF1 3.47e-47 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 23165 FUN_012386 613 144 102 497 278 ptg000008l:8525998-8526841 Q01133 2.77e-31 Antho-RFamide neuropeptides [Cleaved into: Antho-RFamide] Calliactis parasitica (Sea anemone) (Actinia parasitica) neuropeptide signaling pathway [GO:0007218] GO:0005576; GO:0007218 23166 FUN_002233 148 351 179 157 120 NA NA NA NA NA NA NA 23167 FUN_002232 1 0 0 0 10 NA NA NA NA NA NA NA 23168 FUN_042239 137 0 0 0 0 NA NA NA NA NA NA NA 23169 FUN_012387 2492 3400 553 2062 1621 NA NA NA NA NA NA NA 23170 FUN_016118 56 46 50 13 28 NA NA NA NA NA NA NA 23171 FUN_042110 90 221 265 65 242 ptg000036l:669954-675329 Q9CPR1 1.03e-30 RWD domain-containing protein 4 Mus musculus (Mouse) NA NA 23172 FUN_016111 2783 922 1590 2084 1294 NA NA NA NA NA NA NA 23173 FUN_042233 0 0 4 0 23 NA NA NA NA NA NA NA 23174 FUN_016112 2091 1785 1482 3158 2480 NA NA NA NA NA NA NA 23175 FUN_016115 716 1069 617 498 473 NA NA NA NA NA NA NA 23176 FUN_000609 57 38 56 137 9 NA NA NA NA NA NA NA 23177 FUN_016114 128 168 105 252 268 NA NA NA NA NA NA NA 23178 FUN_042237 25 18 37 0 237 NA NA NA NA NA NA NA 23179 FUN_004990 719 296 232 454 734 ntLink_8:29590652-29602133 Q8C0D5 9.65e-57 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Mus musculus (Mouse) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 23180 FUN_004990 719 296 232 454 734 ntLink_8:29590652-29602133 Q8C0D5 9.38e-37 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Mus musculus (Mouse) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 23181 FUN_004990 719 296 232 454 734 ntLink_8:29590652-29602133 Q8C0D5 3.48e-33 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Mus musculus (Mouse) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 23182 FUN_004990 719 296 232 454 734 ntLink_8:29590652-29602133 Q8C0D5 5.86e-22 Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A) Mus musculus (Mouse) cytosolic ribosome assembly [GO:0042256]; GTP metabolic process [GO:0046039] GO:0003746; GO:0003924; GO:0005525; GO:0042256; GO:0043022; GO:0046039; GO:1990904 23183 FUN_004991 129 52 18 466 219 NA NA NA NA NA NA NA 23184 FUN_004994 0 0 0 0 38 NA NA NA NA NA NA NA 23185 FUN_040419 533 258 154 595 394 NA NA NA NA NA NA NA 23186 FUN_040418 0 0 0 0 10 NA NA NA NA NA NA NA 23187 FUN_040412 0 0 28 0 0 NA NA NA NA NA NA NA 23188 FUN_040410 1347 696 421 1902 1467 NA NA NA NA NA NA NA 23189 FUN_040417 4 0 4 47 71 NA NA NA NA NA NA NA 23190 FUN_040415 0 0 770 0 3 ptg000031l:8090164-8094241 Q98993 8.42e-52 Verrucotoxin subunit beta (VTX subunit beta) Synanceia verrucosa (Reef stonefish) hemolysis in another organism [GO:0044179] GO:0005246; GO:0005576; GO:0015459; GO:0044179; GO:0090729 23191 FUN_040414 41 31 29 10 0 NA NA NA NA NA NA NA 23192 FUN_002902 35 0 0 0 0 NA NA NA NA NA NA NA 23193 FUN_002901 35 52 19 20 86 NA NA NA NA NA NA NA 23194 FUN_002900 0 0 0 0 8 NA NA NA NA NA NA NA 23195 FUN_002905 0 5 0 0 8 NA NA NA NA NA NA NA 23196 FUN_002909 0 0 0 0 13 NA NA NA NA NA NA NA 23197 FUN_032481 573 205 164 242 431 NA NA NA NA NA NA NA 23198 FUN_032480 637 529 116 592 469 NA NA NA NA NA NA NA 23199 FUN_032483 0 40 0 277 36 NA NA NA NA NA NA NA 23200 FUN_032482 63 44 27 29 17 NA NA NA NA NA NA NA 23201 FUN_032485 0 2 3 110 1 NA NA NA NA NA NA NA 23202 FUN_032484 0 27 0 225 26 NA NA NA NA NA NA NA 23203 FUN_032487 1393 1409 889 1685 1380 NA NA NA NA NA NA NA 23204 FUN_032486 29 15 0 20 17 NA NA NA NA NA NA NA 23205 FUN_032489 1341 1018 689 1143 873 NA NA NA NA NA NA NA 23206 FUN_032488 1953 2188 1396 2817 2210 NA NA NA NA NA NA NA 23207 FUN_018371 13 0 0 0 3 NA NA NA NA NA NA NA 23208 FUN_034361 2076 2856 1491 2226 2036 NA NA NA NA NA NA NA 23209 FUN_018377 33 5 9 29 54 ptg000012l:8662452-8665789 P81274 3.26e-51 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23210 FUN_018377 33 5 9 29 54 ptg000012l:8662452-8665789 P81274 1.71e-44 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23211 FUN_018377 33 5 9 29 54 ptg000012l:8662452-8665789 P81274 4.98e-36 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23212 FUN_018377 33 5 9 29 54 ptg000012l:8662452-8665789 P81274 1.18e-30 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23213 FUN_034367 3533 2513 1529 1384 1224 NA NA NA NA NA NA NA 23214 FUN_018375 49 8 14 39 8 NA NA NA NA NA NA NA 23215 FUN_034365 5013 5919 3769 4341 4879 NA NA NA NA NA NA NA 23216 FUN_008426 4529 5667 2682 5429 3551 ptg000002l:11421473-11434277 Q9D7N9 3.24e-34 Adipocyte plasma membrane-associated protein (Protein DD16) Mus musculus (Mouse) biosynthetic process [GO:0009058] GO:0004064; GO:0009058; GO:0009986; GO:0016020; GO:0016844 23217 FUN_008427 1325 1098 711 859 891 ptg000002l:11435936-11443863 O45924 1.96e-39 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) Caenorhabditis elegans branched-chain amino acid catabolic process [GO:0009083]; fatty acid biosynthetic process [GO:0006633] GO:0003863; GO:0005947; GO:0006633; GO:0009083; GO:0046872 23218 FUN_008424 220 5 0 10 19 NA NA NA NA NA NA NA 23219 FUN_008425 57 0 0 0 18 NA NA NA NA NA NA NA 23220 FUN_008422 1184 471 445 947 1058 ptg000002l:11371797-11401043 P15206 2.34e-31 G2/mitotic-specific cyclin-B Marthasterias glacialis (Spiny starfish) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0016538; GO:0044772; GO:0051301 23221 FUN_008422 1184 471 445 947 1058 ptg000002l:11371797-11401043 P15206 2.34e-31 G2/mitotic-specific cyclin-B Marthasterias glacialis (Spiny starfish) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0016538; GO:0044772; GO:0051301 23222 FUN_008423 94 0 0 0 0 NA NA NA NA NA NA NA 23223 FUN_008420 34 42 45 80 73 NA NA NA NA NA NA NA 23224 FUN_008421 781 537 486 857 650 NA NA NA NA NA NA NA 23225 FUN_018379 57 49 23 132 129 NA NA NA NA NA NA NA 23226 FUN_008428 2366 4455 2062 2741 1417 NA NA NA NA NA NA NA 23227 FUN_008429 1669 962 983 1071 856 NA NA NA NA NA NA NA 23228 FUN_000215 2790 1245 1302 2216 2281 NA NA NA NA NA NA NA 23229 FUN_000217 339 239 289 253 460 NA NA NA NA NA NA NA 23230 FUN_000213 2974 1554 1059 3330 49 ntLink_6:333958-346093 Q8LHH9 3.26e-54 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 23231 FUN_000213 2974 1554 1059 3330 49 ntLink_6:333958-346093 Q8LHH9 5.28e-23 Probable RNA-dependent RNA polymerase SHL2 (EC 2.7.7.48) (Protein SHOOTLESS 2) Oryza sativa subsp. japonica (Rice) maintenance of shoot apical meristem identity [GO:0010492]; RNA-mediated post-transcriptional gene silencing [GO:0035194]; siRNA processing [GO:0030422] GO:0003723; GO:0003968; GO:0010492; GO:0030422; GO:0031380; GO:0035194 23232 FUN_041426 4489 9613 2570 12048 6230 NA NA NA NA NA NA NA 23233 FUN_041429 56 91 0 41 17 NA NA NA NA NA NA NA 23234 FUN_000219 1630 1123 691 1076 941 NA NA NA NA NA NA NA 23235 FUN_033286 0 0 0 0 17 NA NA NA NA NA NA NA 23236 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 1.67e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23237 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 2e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23238 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 8.08e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23239 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 3.38e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23240 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 2.3e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23241 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 2.3e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23242 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 2.41e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23243 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 7.5e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23244 FUN_033287 158 121 43 198 356 ptg000023l:41513626-41515480 Q96AY4 7.5e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23245 FUN_033281 0 0 8 0 9 NA NA NA NA NA NA NA 23246 FUN_029064 66 0 0 0 31 NA NA NA NA NA NA NA 23247 FUN_012651 1558 1630 1446 1263 357 NA NA NA NA NA NA NA 23248 FUN_029149 6257 3995 2448 6732 4348 ptg000022l:8690545-8711753 Q80TJ1 2.51e-68 Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) Mus musculus (Mouse) catecholamine secretion [GO:0050432]; establishment of localization in cell [GO:0051649]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein transport [GO:0015031]; synaptic vesicle priming [GO:0016082]; vesicle organization [GO:0016050] GO:0005509; GO:0005546; GO:0015031; GO:0016050; GO:0016082; GO:0019901; GO:0031045; GO:0031410; GO:0045921; GO:0045956; GO:0050432; GO:0051649; GO:0098674; GO:0098793; GO:0098978; GO:0099525 23249 FUN_029149 6257 3995 2448 6732 4348 ptg000022l:8690545-8711753 Q80TJ1 9.33e-27 Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1) Mus musculus (Mouse) catecholamine secretion [GO:0050432]; establishment of localization in cell [GO:0051649]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of exocytosis [GO:0045921]; presynaptic dense core vesicle exocytosis [GO:0099525]; protein transport [GO:0015031]; synaptic vesicle priming [GO:0016082]; vesicle organization [GO:0016050] GO:0005509; GO:0005546; GO:0015031; GO:0016050; GO:0016082; GO:0019901; GO:0031045; GO:0031410; GO:0045921; GO:0045956; GO:0050432; GO:0051649; GO:0098674; GO:0098793; GO:0098978; GO:0099525 23250 FUN_029140 81 47 12 50 48 NA NA NA NA NA NA NA 23251 FUN_029141 217 84 107 189 279 NA NA NA NA NA NA NA 23252 FUN_029142 82 28 18 43 84 NA NA NA NA NA NA NA 23253 FUN_029143 0 0 16 0 0 NA NA NA NA NA NA NA 23254 FUN_029144 3805 2754 2277 3481 3531 NA NA NA NA NA NA NA 23255 FUN_029145 938 899 364 1135 619 NA NA NA NA NA NA NA 23256 FUN_029146 0 0 24 0 0 NA NA NA NA NA NA NA 23257 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 6.22e-109 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23258 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 3.75e-69 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23259 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 2.02e-58 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23260 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 9.79e-53 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23261 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 4.05e-48 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23262 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 9.14e-48 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23263 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 8.17e-47 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23264 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 1.89e-41 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23265 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 1.89e-41 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23266 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 6.4e-41 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23267 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 2.35e-40 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23268 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 2.37e-40 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23269 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 2.37e-40 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23270 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 3.1e-33 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23271 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 6.7e-30 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23272 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 9.01e-29 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23273 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 2.91e-28 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23274 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 4.58e-28 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23275 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 7.41e-27 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23276 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 4.38e-26 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23277 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 4.38e-26 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23278 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 4.09e-24 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23279 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 6.37e-24 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23280 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 2.01e-23 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23281 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 5.59e-23 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23282 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 1.08e-22 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23283 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 1.1e-21 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23284 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 1.49e-21 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23285 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 3.54e-21 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23286 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 3.54e-21 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23287 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 4.91e-21 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23288 FUN_029147 27886 25107 18976 45861 31204 ptg000022l:8670446-8688546 P21333 5.21e-21 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin) Homo sapiens (Human) actin crosslink formation [GO:0051764]; actin cytoskeleton reorganization [GO:0031532]; adenylate cyclase-inhibiting dopamine receptor signaling pathway [GO:0007195]; angiogenesis [GO:0001525]; blood coagulation, intrinsic pathway [GO:0007597]; blood vessel remodeling [GO:0001974]; cell-cell junction organization [GO:0045216]; cilium assembly [GO:0060271]; cytoplasmic sequestering of protein [GO:0051220]; early endosome to late endosome transport [GO:0045022]; epithelial to mesenchymal transition [GO:0001837]; establishment of protein localization [GO:0045184]; heart morphogenesis [GO:0003007]; megakaryocyte development [GO:0035855]; mitotic spindle assembly [GO:0090307]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of transcription by RNA polymerase I [GO:0016479]; platelet aggregation [GO:0070527]; positive regulation of axon regeneration [GO:0048680]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of platelet activation [GO:0010572]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; protein stabilization [GO:0050821]; receptor clustering [GO:0043113]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell migration [GO:0030334]; regulation of membrane repolarization during atrial cardiac muscle cell action potential [GO:1905000]; regulation of membrane repolarization during cardiac muscle cell action potential [GO:1905031]; release of sequestered calcium ion into cytosol [GO:0051209]; semaphorin-plexin signaling pathway [GO:0071526]; synapse organization [GO:0050808]; tubulin deacetylation [GO:0090042]; wound healing, spreading of cells [GO:0044319] GO:0001525; GO:0001664; GO:0001837; GO:0001974; GO:0003007; GO:0003723; GO:0005080; GO:0005576; GO:0005634; GO:0005730; GO:0005737; GO:0005802; GO:0005829; GO:0005886; GO:0005903; GO:0005911; GO:0005925; GO:0005938; GO:0007195; GO:0007597; GO:0010572; GO:0010977; GO:0015459; GO:0015629; GO:0016020; GO:0016479; GO:0019900; GO:0030018; GO:0030334; GO:0031267; GO:0031523; GO:0031532; GO:0032231; GO:0032432; GO:0034394; GO:0034988; GO:0035855; GO:0042177; GO:0042307; GO:0042803; GO:0043066; GO:0043113; GO:0043123; GO:0043204; GO:0043433; GO:0044295; GO:0044319; GO:0044325; GO:0045022; GO:0045184; GO:0045216; GO:0045296; GO:0048680; GO:0050808; GO:0050821; GO:0051015; GO:0051020; GO:0051209; GO:0051220; GO:0051764; GO:0060271; GO:0070062; GO:0070527; GO:0071526; GO:0072659; GO:0090042; GO:0090307; GO:0140297; GO:1900026; GO:1901381; GO:1905000; GO:1905031; GO:1990779; GO:2001046 23289 FUN_016999 0 143 39 310 7 ptg000011l:10053763-10062303 R1CW23 1e-96 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 23290 FUN_016991 41 36 8 41 23 NA NA NA NA NA NA NA 23291 FUN_016990 768 424 458 1205 797 NA NA NA NA NA NA NA 23292 FUN_016992 48 11 11 78 28 ptg000011l:9995340-9996507 Q9EQD2 1.36e-36 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 23293 FUN_016995 1525 1390 200 768 4407 ptg000011l:10022811-10023552 R1CW23 1.39e-90 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 23294 FUN_016994 7 3 0 3 12 NA NA NA NA NA NA NA 23295 FUN_033756 2585 1474 1418 2815 2454 NA NA NA NA NA NA NA 23296 FUN_033757 981 701 388 657 807 NA NA NA NA NA NA NA 23297 FUN_033754 21768 23068 13965 22856 13531 NA NA NA NA NA NA NA 23298 FUN_033755 183 36 87 62 136 ptg000024l:1002625-1003774 P16389 7.43e-98 Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2) Homo sapiens (Human) cerebral cortex development [GO:0021987]; corpus callosum development [GO:0022038]; neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion export across plasma membrane [GO:0097623]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005267; GO:0005789; GO:0005886; GO:0006813; GO:0008076; GO:0014059; GO:0015271; GO:0016020; GO:0019228; GO:0019233; GO:0019894; GO:0021633; GO:0021987; GO:0022038; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045188; GO:0045211; GO:0051260; GO:0071805; GO:0097623; GO:0098978; GO:0099508; GO:1905030 23299 FUN_033752 6765 5927 3637 6388 5591 NA NA NA NA NA NA NA 23300 FUN_033753 55494 51918 47393 59136 51960 NA NA NA NA NA NA NA 23301 FUN_033751 4165 3757 3242 3770 3776 ptg000024l:934217-951112 Q66PG3 2.35e-22 Xylosyl- and glucuronyltransferase LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A) (Glycosyltransferase-like protein) [Includes: Alpha-1,3-xylosyltransferase LARGE1 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE1 (EC 2.4.1.-)] Gallus gallus (Chicken) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue regeneration [GO:0043403] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0016758; GO:0030145; GO:0035269; GO:0042285; GO:0043403; GO:0060538 23302 FUN_033751 4165 3757 3242 3770 3776 ptg000024l:934217-951112 Q66PG3 2.35e-22 Xylosyl- and glucuronyltransferase LARGE1 (EC 2.4.-.-) (Acetylglucosaminyltransferase-like 1A) (Glycosyltransferase-like protein) [Includes: Alpha-1,3-xylosyltransferase LARGE1 (EC 2.4.2.-); Beta-1,3-glucuronyltransferase LARGE1 (EC 2.4.1.-)] Gallus gallus (Chicken) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269]; skeletal muscle organ development [GO:0060538]; skeletal muscle tissue regeneration [GO:0043403] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0016758; GO:0030145; GO:0035269; GO:0042285; GO:0043403; GO:0060538 23303 FUN_028895 0 0 0 24 21 NA NA NA NA NA NA NA 23304 FUN_028894 472 367 395 631 540 ptg000022l:5656303-5661328 O08520 5.32e-32 CMP-sialic acid transporter (CMP-SA-Tr) (CMP-Sia-Tr) (Solute carrier family 35 member A1) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) carbohydrate transport [GO:0008643]; CMP-N-acetylneuraminate transmembrane transport [GO:0015782] GO:0000139; GO:0005456; GO:0008643; GO:0015297; GO:0015782; GO:0016020 23305 FUN_028897 1337 882 446 836 606 NA NA NA NA NA NA NA 23306 FUN_028896 61 14 20 25 54 NA NA NA NA NA NA NA 23307 FUN_028891 196 149 51 138 35 ptg000022l:5637727-5639348 Q804Q5 4.22e-63 Fez family zinc finger protein 2 (Forebrain embryonic zinc finger-like protein 2) (Foreheadin protein) (Zinc finger protein Fez-like) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system development [GO:0007417]; central nervous system neuron development [GO:0021954]; commissural neuron axon guidance [GO:0071679]; diencephalon development [GO:0021536]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; mammillary body development [GO:0021767]; negative regulation of DNA-templated transcription [GO:0045892]; nervous system development [GO:0007399]; neuronal stem cell population maintenance [GO:0097150]; regulation of Notch signaling pathway [GO:0008593]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007399; GO:0007417; GO:0008593; GO:0021536; GO:0021767; GO:0021854; GO:0021879; GO:0021954; GO:0030900; GO:0045892; GO:0046872; GO:0071679; GO:0097150 23308 FUN_028890 0 0 0 4 23 NA NA NA NA NA NA NA 23309 FUN_033758 17 0 0 0 9 NA NA NA NA NA NA NA 23310 FUN_028892 49 45 78 70 97 NA NA NA NA NA NA NA 23311 FUN_003748 10 0 0 0 32 NA NA NA NA NA NA NA 23312 FUN_003749 0 0 0 0 12 NA NA NA NA NA NA NA 23313 FUN_038415 4975 4742 2269 2960 2504 NA NA NA NA NA NA NA 23314 FUN_003742 2 0 16 0 46 NA NA NA NA NA NA NA 23315 FUN_003845 375 428 246 267 100 NA NA NA NA NA NA NA 23316 FUN_038417 714 857 91 225 277 ptg000027l:6970618-6971548 Q28955 1.3e-69 Protein N-terminal asparagine amidohydrolase (EC 3.5.1.121) (Protein NH2-terminal asparagine amidohydrolase) (PNAA) (Protein NH2-terminal asparagine deamidase) (PNAD) (Protein N-terminal Asn amidase) (Protein NTN-amidase) Sus scrofa (Pig) adult locomotory behavior [GO:0008344]; memory [GO:0007613]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005737; GO:0006511; GO:0007613; GO:0008344; GO:0008418 23317 FUN_003844 1507 2159 1366 1524 1628 NA NA NA NA NA NA NA 23318 FUN_003847 338 197 285 201 276 NA NA NA NA NA NA NA 23319 FUN_004814 33 0 36 16 25 ntLink_8:27296542-27303605 Q658G7 3.28e-21 LRR receptor-like serine/threonine-protein kinase SIK1 (EC 2.7.11.1) (ERECTA homolog 2) (ER homolog 2) (OsER2) (Stress-induced protein kinase 1) (OsSIK1) Oryza sativa subsp. japonica (Rice) positive regulation of response to salt stress [GO:1901002]; positive regulation of response to water deprivation [GO:1902584]; protein phosphorylation [GO:0006468]; regulation of stomatal complex development [GO:2000038] GO:0004675; GO:0005524; GO:0005886; GO:0006468; GO:0106310; GO:1901002; GO:1902584; GO:2000038 23320 FUN_003843 314 321 411 341 160 ntLink_8:15964588-15971338 P51687 2.63e-85 Sulfite oxidase, mitochondrial (EC 1.8.3.1) Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] GO:0005739; GO:0005758; GO:0005759; GO:0006790; GO:0008482; GO:0020037; GO:0030151; GO:0043546 23321 FUN_003843 314 321 411 341 160 ntLink_8:15964588-15971338 P51687 5.54e-23 Sulfite oxidase, mitochondrial (EC 1.8.3.1) Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] GO:0005739; GO:0005758; GO:0005759; GO:0006790; GO:0008482; GO:0020037; GO:0030151; GO:0043546 23322 FUN_003843 314 321 411 341 160 ntLink_8:15964588-15971338 P51687 2.99e-22 Sulfite oxidase, mitochondrial (EC 1.8.3.1) Homo sapiens (Human) sulfur compound metabolic process [GO:0006790] GO:0005739; GO:0005758; GO:0005759; GO:0006790; GO:0008482; GO:0020037; GO:0030151; GO:0043546 23323 FUN_028843 2453 3296 1018 2462 955 NA NA NA NA NA NA NA 23324 FUN_023812 0 10 0 0 7 NA NA NA NA NA NA NA 23325 FUN_028239 561 348 332 638 407 ptg000021l:17257542-17271353 Q9DBT5 2.44e-29 AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) Mus musculus (Mouse) AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cholesterol homeostasis [GO:0042632]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GMP salvage [GO:0032263]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; nucleotide metabolic process [GO:0009117]; podocyte development [GO:0072015] GO:0003876; GO:0005829; GO:0006188; GO:0009117; GO:0032263; GO:0032264; GO:0042632; GO:0042802; GO:0046033; GO:0046034; GO:0046039; GO:0046872; GO:0052652; GO:0072015; GO:0097009 23326 FUN_028239 561 348 332 638 407 ptg000021l:17257542-17271353 Q9DBT5 6.44e-22 AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) Mus musculus (Mouse) AMP metabolic process [GO:0046033]; ATP metabolic process [GO:0046034]; cholesterol homeostasis [GO:0042632]; cyclic purine nucleotide metabolic process [GO:0052652]; energy homeostasis [GO:0097009]; GMP salvage [GO:0032263]; GTP metabolic process [GO:0046039]; IMP biosynthetic process [GO:0006188]; IMP salvage [GO:0032264]; nucleotide metabolic process [GO:0009117]; podocyte development [GO:0072015] GO:0003876; GO:0005829; GO:0006188; GO:0009117; GO:0032263; GO:0032264; GO:0042632; GO:0042802; GO:0046033; GO:0046034; GO:0046039; GO:0046872; GO:0052652; GO:0072015; GO:0097009 23327 FUN_010769 1630 455 456 1160 737 ptg000007l:2607191-2608271 E7F7V7 4e-25 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 23328 FUN_028231 183 300 182 552 530 ptg000021l:17132394-17144641 Q7Z494 2.84e-40 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 23329 FUN_028231 183 300 182 552 530 ptg000021l:17132394-17144641 Q7Z494 7.71e-32 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 23330 FUN_028231 183 300 182 552 530 ptg000021l:17132394-17144641 Q7Z494 3.53e-23 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 23331 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 5.77e-32 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23332 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 5.77e-32 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23333 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 1.05e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23334 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 1.05e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23335 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 1.33e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23336 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 1.33e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23337 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 3.59e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23338 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 7.46e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23339 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 7.46e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23340 FUN_028230 250 172 63 184 640 ptg000021l:17130791-17132246 P0CI65 7.46e-23 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 23341 FUN_028232 815 567 433 510 522 NA NA NA NA NA NA NA 23342 FUN_028235 76 62 23 47 36 NA NA NA NA NA NA NA 23343 FUN_010765 135 69 21 285 55 NA NA NA NA NA NA NA 23344 FUN_010766 7 21 1 0 33 NA NA NA NA NA NA NA 23345 FUN_010767 256 260 145 206 181 ptg000007l:2583875-2598607 P15145 5.44e-30 Aminopeptidase N (AP-N) (pAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (gp130) (CD antigen CD13) Sus scrofa (Pig) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; peptide catabolic process [GO:0043171]; proteolysis [GO:0006508]; regulation of blood pressure [GO:0008217]; signal transduction [GO:0007165] GO:0001525; GO:0001618; GO:0005737; GO:0005886; GO:0006508; GO:0007165; GO:0008217; GO:0008270; GO:0030154; GO:0042277; GO:0043171; GO:0070006 23346 FUN_028845 0 6 0 0 0 NA NA NA NA NA NA NA 23347 FUN_012692 187 200 270 213 210 ptg000008l:11421644-11423543 P30825 2.17e-32 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1903352; GO:1903810; GO:1903826 23348 FUN_012693 803 465 300 977 429 ptg000008l:11430986-11433263 Q8NB59 1.62e-31 Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) Homo sapiens (Human) NA GO:0005543; GO:0016020 23349 FUN_012690 50 16 11 0 13 ptg000008l:11405431-11407145 O43246 2.7e-66 Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4) Homo sapiens (Human) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0016020 23350 FUN_012691 1389 950 704 1107 615 ptg000008l:11409232-11421063 Q6DCE8 5.51e-136 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Xenopus laevis (African clawed frog) L-arginine transmembrane transport [GO:1903826] GO:0005886; GO:0061459; GO:1903826 23351 FUN_012691 1389 950 704 1107 615 ptg000008l:11409232-11421063 Q6DCE8 5.02e-73 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Xenopus laevis (African clawed frog) L-arginine transmembrane transport [GO:1903826] GO:0005886; GO:0061459; GO:1903826 23352 FUN_012696 1166 1013 700 1423 1081 NA NA NA NA NA NA NA 23353 FUN_012697 933 475 385 885 655 NA NA NA NA NA NA NA 23354 FUN_012694 1176 1800 965 1040 553 ptg000008l:11436362-11437115 Q8NB59 8.33e-21 Synaptotagmin-14 (Synaptotagmin XIV) (SytXIV) Homo sapiens (Human) NA GO:0005543; GO:0016020 23355 FUN_012695 0 4 35 4 25 NA NA NA NA NA NA NA 23356 FUN_012698 2629 1125 1316 1461 1230 NA NA NA NA NA NA NA 23357 FUN_012699 1960 1096 785 1250 1249 ptg000008l:11486186-11496715 Q9EPS3 3.37e-94 D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase) Mus musculus (Mouse) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] GO:0000139; GO:0005509; GO:0005794; GO:0015012; GO:0016857; GO:0030210; GO:0042803; GO:0047464; GO:0050379 23358 FUN_012699 1960 1096 785 1250 1249 ptg000008l:11486186-11496715 Q9EPS3 2.93e-34 D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin sulfate C5-epimerase) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase) Mus musculus (Mouse) heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparin biosynthetic process [GO:0030210] GO:0000139; GO:0005509; GO:0005794; GO:0015012; GO:0016857; GO:0030210; GO:0042803; GO:0047464; GO:0050379 23359 FUN_034362 12 0 0 27 48 NA NA NA NA NA NA NA 23360 FUN_011419 1683 919 1065 2014 1743 NA NA NA NA NA NA NA 23361 FUN_043138 265 369 156 509 378 NA NA NA NA NA NA NA 23362 FUN_043130 1678 1452 1130 928 822 NA NA NA NA NA NA NA 23363 FUN_043133 1375 759 358 900 444 NA NA NA NA NA NA NA 23364 FUN_011412 8 33 34 0 0 NA NA NA NA NA NA NA 23365 FUN_011415 119 67 56 14 46 NA NA NA NA NA NA NA 23366 FUN_043134 50 0 3 0 0 NA NA NA NA NA NA NA 23367 FUN_043136 562 377 333 373 352 ptg000047l:4475069-4476263 Q15760 5.66e-35 Probable G-protein coupled receptor 19 (GPR-NGA) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0005929; GO:0007186 23368 FUN_013123 137 85 92 71 289 NA NA NA NA NA NA NA 23369 FUN_013122 540 387 497 421 439 NA NA NA NA NA NA NA 23370 FUN_013121 5498 4798 2910 4497 4147 ptg000008l:19780248-19791553 P60517 2.33e-32 Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) Rattus norvegicus (Rat) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; cellular response to nitrogen starvation [GO:0006995]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; macroautophagy [GO:0016236]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein K48-linked ubiquitination [GO:1902524]; protein transport [GO:0015031]; regulation of Rac protein signal transduction [GO:0035020] GO:0000045; GO:0000139; GO:0000226; GO:0000421; GO:0000422; GO:0005764; GO:0005776; GO:0005790; GO:0005794; GO:0005829; GO:0005874; GO:0005875; GO:0005886; GO:0005930; GO:0006995; GO:0008017; GO:0008625; GO:0015031; GO:0015629; GO:0016236; GO:0031410; GO:0031625; GO:0032436; GO:0035020; GO:0044297; GO:0048471; GO:0048487; GO:0050811; GO:0097225; GO:1902524 23371 FUN_013127 80 38 15 2 40 NA NA NA NA NA NA NA 23372 FUN_013126 32 71 104 80 247 NA NA NA NA NA NA NA 23373 FUN_013124 11 0 0 0 0 NA NA NA NA NA NA NA 23374 FUN_039992 73 0 35 77 92 NA NA NA NA NA NA NA 23375 FUN_029986 0 10 5 1 12 NA NA NA NA NA NA NA 23376 FUN_023768 89 109 74 81 82 NA NA NA NA NA NA NA 23377 FUN_023762 881 624 538 1299 964 NA NA NA NA NA NA NA 23378 FUN_023760 2008 1716 1282 1646 1369 NA NA NA NA NA NA NA 23379 FUN_023761 428 176 144 226 190 NA NA NA NA NA NA NA 23380 FUN_023766 108 3 53 11 213 NA NA NA NA NA NA NA 23381 FUN_023767 78 4 57 55 26 NA NA NA NA NA NA NA 23382 FUN_023765 2649 1082 1775 2582 2404 NA NA NA NA NA NA NA 23383 FUN_009290 19 48 59 58 69 NA NA NA NA NA NA NA 23384 FUN_009291 209 109 55 3 285 NA NA NA NA NA NA NA 23385 FUN_009296 1012 379 498 457 618 NA NA NA NA NA NA NA 23386 FUN_009297 185 44 12 0 45 ptg000004l:5059952-5071678 Q95SX7 7.23e-40 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 23387 FUN_009294 184 6 4 2 197 NA NA NA NA NA NA NA 23388 FUN_009295 364 90 73 0 194 ptg000004l:4981650-5044506 Q9CUX1 7.54e-24 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 23389 FUN_009295 364 90 73 0 194 ptg000004l:4981650-5044506 Q9CUX1 7.54e-24 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 23390 FUN_009298 9446 8752 5194 6604 2620 NA NA NA NA NA NA NA 23391 FUN_009299 52 549 322 338 0 NA NA NA NA NA NA NA 23392 FUN_026682 16 12 49 39 0 NA NA NA NA NA NA NA 23393 FUN_026683 2320 518 406 1707 1565 ptg000020l:12435120-12459372 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23394 FUN_026683 2320 518 406 1707 1565 ptg000020l:12435120-12459372 Q9NZJ4 2.4e-49 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23395 FUN_026683 2320 518 406 1707 1565 ptg000020l:12435120-12459372 Q9NZJ4 1.2e-48 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23396 FUN_026683 2320 518 406 1707 1565 ptg000020l:12435120-12459372 Q9NZJ4 1.46e-47 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23397 FUN_026680 4204 1655 1174 4236 2638 NA NA NA NA NA NA NA 23398 FUN_026681 2835 1827 1666 5097 1481 ptg000020l:12405630-12427664 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23399 FUN_026681 2835 1827 1666 5097 1481 ptg000020l:12405630-12427664 Q9NZJ4 1.74e-53 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23400 FUN_026681 2835 1827 1666 5097 1481 ptg000020l:12405630-12427664 Q9NZJ4 1.71e-46 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23401 FUN_026681 2835 1827 1666 5097 1481 ptg000020l:12405630-12427664 Q9NZJ4 4.39e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 23402 FUN_026686 749 214 245 408 529 ptg000020l:12486188-12492478 Q86SG6 2.4e-119 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; chromosome segregation [GO:0007059]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0007368; GO:0007507; GO:0009887; GO:0035330; GO:0046872; GO:0097543; GO:0097546; GO:0106310 23403 FUN_026686 749 214 245 408 529 ptg000020l:12486188-12492478 Q86SG6 2.68e-44 Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; chromosome segregation [GO:0007059]; determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; protein phosphorylation [GO:0006468]; regulation of hippo signaling [GO:0035330] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005929; GO:0006468; GO:0007059; GO:0007368; GO:0007507; GO:0009887; GO:0035330; GO:0046872; GO:0097543; GO:0097546; GO:0106310 23404 FUN_026687 656 257 169 316 105 NA NA NA NA NA NA NA 23405 FUN_026684 91 14 84 130 112 NA NA NA NA NA NA NA 23406 FUN_026685 827 913 435 610 390 NA NA NA NA NA NA NA 23407 FUN_026688 0 0 0 3 12 ptg000020l:12501272-12504735 Q28044 7.57e-23 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Bos taurus (Bovine) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 23408 FUN_026689 25 0 0 4 9 NA NA NA NA NA NA NA 23409 FUN_015406 72 70 0 14 24 NA NA NA NA NA NA NA 23410 FUN_015407 1363 875 359 750 1902 NA NA NA NA NA NA NA 23411 FUN_015404 61 0 19 120 350 NA NA NA NA NA NA NA 23412 FUN_015405 2121 1277 1058 1094 687 ptg000009l:9800612-9801743 Q26619 1.19e-115 cAMP-dependent protein kinase type II regulatory subunit Strongylocentrotus purpuratus (Purple sea urchin) negative regulation of cAMP-dependent protein kinase activity [GO:2000480] GO:0004862; GO:0005737; GO:0005952; GO:0030552; GO:0034236; GO:2000480 23413 FUN_015402 529 235 141 374 388 NA NA NA NA NA NA NA 23414 FUN_015403 121 315 93 104 111 NA NA NA NA NA NA NA 23415 FUN_015400 605 138 150 615 550 NA NA NA NA NA NA NA 23416 FUN_015401 857 95 223 552 472 NA NA NA NA NA NA NA 23417 FUN_029101 96 74 21 88 86 NA NA NA NA NA NA NA 23418 FUN_015408 2307 1665 879 1527 859 NA NA NA NA NA NA NA 23419 FUN_015409 46 10 56 0 133 NA NA NA NA NA NA NA 23420 FUN_025089 107 0 106 17 525 NA NA NA NA NA NA NA 23421 FUN_025088 669 369 92 403 188 ptg000018l:13608086-13620177 P20825 2.31e-43 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 23422 FUN_025088 669 369 92 403 188 ptg000018l:13608086-13620177 P20825 2.31e-43 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 23423 FUN_025088 669 369 92 403 188 ptg000018l:13608086-13620177 P20825 2.31e-43 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 23424 FUN_025085 0 6 0 6 5 NA NA NA NA NA NA NA 23425 FUN_025087 92 0 16 110 43 NA NA NA NA NA NA NA 23426 FUN_017929 1292 900 698 1222 1085 ptg000012l:2029399-2061765 O75165 2.71e-37 DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8) Homo sapiens (Human) endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] GO:0001649; GO:0005765; GO:0005829; GO:0005886; GO:0006898; GO:0007032; GO:0010008; GO:0015031; GO:0016020; GO:0030667; GO:0031901; GO:0035577; GO:0043231; GO:0070062; GO:1902954; GO:2000641 23427 FUN_017929 1292 900 698 1222 1085 ptg000012l:2029399-2061765 O75165 1.09e-21 DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8) Homo sapiens (Human) endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] GO:0001649; GO:0005765; GO:0005829; GO:0005886; GO:0006898; GO:0007032; GO:0010008; GO:0015031; GO:0016020; GO:0030667; GO:0031901; GO:0035577; GO:0043231; GO:0070062; GO:1902954; GO:2000641 23428 FUN_017927 1253 914 859 840 821 NA NA NA NA NA NA NA 23429 FUN_017926 642 358 490 753 636 NA NA NA NA NA NA NA 23430 FUN_017925 655 633 387 695 547 ptg000012l:1937418-1944035 P18700 1.34e-97 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 23431 FUN_017925 655 633 387 695 547 ptg000012l:1937418-1944035 P18700 3.26e-40 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 23432 FUN_017924 566 241 293 465 357 NA NA NA NA NA NA NA 23433 FUN_017923 1496 1011 903 1512 1342 ptg000012l:1916853-1929050 Q9BZJ0 2.9e-42 Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000974; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0016607; GO:0071007; GO:0071013; GO:0071014 23434 FUN_017923 1496 1011 903 1512 1342 ptg000012l:1916853-1929050 Q9BZJ0 2.35e-24 Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) Homo sapiens (Human) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000974; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0016607; GO:0071007; GO:0071013; GO:0071014 23435 FUN_018750 3 4 13 0 9 NA NA NA NA NA NA NA 23436 FUN_017920 1165 624 687 1067 987 NA NA NA NA NA NA NA 23437 FUN_024932 110 125 0 27 0 NA NA NA NA NA NA NA 23438 FUN_024933 23 24 3 16 41 NA NA NA NA NA NA NA 23439 FUN_024930 21 37 9 0 0 NA NA NA NA NA NA NA 23440 FUN_024931 40 135 0 0 34 NA NA NA NA NA NA NA 23441 FUN_024936 0 0 13 0 0 NA NA NA NA NA NA NA 23442 FUN_024937 0 0 0 13 0 NA NA NA NA NA NA NA 23443 FUN_024935 0 0 0 13 4 NA NA NA NA NA NA NA 23444 FUN_024938 7 11 9 20 0 NA NA NA NA NA NA NA 23445 FUN_038252 1707 930 654 1311 894 NA NA NA NA NA NA NA 23446 FUN_038253 616 717 197 373 226 NA NA NA NA NA NA NA 23447 FUN_038250 226 254 80 59 176 NA NA NA NA NA NA NA 23448 FUN_038251 4 60 2 1 23 NA NA NA NA NA NA NA 23449 FUN_038256 4801 4319 2592 3700 2713 NA NA NA NA NA NA NA 23450 FUN_038257 5363 6213 3118 3218 2115 NA NA NA NA NA NA NA 23451 FUN_038254 54 116 23 198 59 NA NA NA NA NA NA NA 23452 FUN_038255 206 172 221 243 406 ptg000027l:4770929-4772207 Q91ZE0 4.95e-87 Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD) Mus musculus (Mouse) carnitine biosynthetic process [GO:0045329]; negative regulation of oxidoreductase activity [GO:0051354] GO:0005506; GO:0005739; GO:0005759; GO:0016702; GO:0045329; GO:0050353; GO:0051354 23453 FUN_038258 2052 822 923 1789 1322 NA NA NA NA NA NA NA 23454 FUN_038259 416 262 276 871 592 NA NA NA NA NA NA NA 23455 FUN_025332 0 0 0 20 0 NA NA NA NA NA NA NA 23456 FUN_025331 4968 2991 2391 3713 2122 ptg000019l:1357904-1385093 Q5F499 3.77e-23 Dynamin-like 120 kDa protein, mitochondrial (EC 3.6.5.5) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like 120 kDa protein, form S1] Gallus gallus (Chicken) apoptotic process [GO:0006915]; GTP metabolic process [GO:0046039]; membrane tubulation [GO:0097749]; mitochondrial fusion [GO:0008053] GO:0003924; GO:0005525; GO:0005737; GO:0005743; GO:0005758; GO:0005874; GO:0006915; GO:0008017; GO:0008053; GO:0016020; GO:0031966; GO:0046039; GO:0070300; GO:0097749; GO:1901612 23457 FUN_025330 620 328 334 272 396 NA NA NA NA NA NA NA 23458 FUN_025337 88 158 192 105 108 NA NA NA NA NA NA NA 23459 FUN_025335 2671 1608 1906 2776 2345 NA NA NA NA NA NA NA 23460 FUN_025334 4 44 0 0 17 NA NA NA NA NA NA NA 23461 FUN_025339 0 0 0 15 21 NA NA NA NA NA NA NA 23462 FUN_025338 3 0 0 9 229 NA NA NA NA NA NA NA 23463 FUN_024685 0 3 0 0 121 NA NA NA NA NA NA NA 23464 FUN_024686 0 0 0 0 7 NA NA NA NA NA NA NA 23465 FUN_024687 0 0 13 29 58 NA NA NA NA NA NA NA 23466 FUN_024680 603 347 380 767 808 NA NA NA NA NA NA NA 23467 FUN_024681 1 37 13 5 30 NA NA NA NA NA NA NA 23468 FUN_024682 24524 28030 13866 25623 9302 ptg000018l:9826959-9829645 P22125 8.34e-34 Ras-related protein ORAB-1 Diplobatis ommata (Ocellated electric ray) (Discopyge ommata) protein transport [GO:0015031] GO:0003924; GO:0005525; GO:0005886; GO:0015031 23469 FUN_024689 21 0 0 0 24 NA NA NA NA NA NA NA 23470 FUN_019406 64 0 0 50 33 ptg000015l:1881067-1901525 P06872 9.39e-25 Anionic trypsin (EC 3.4.21.4) Canis lupus familiaris (Dog) (Canis familiaris) collagen catabolic process [GO:0030574]; digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005509; GO:0005576; GO:0005615; GO:0006508; GO:0007586; GO:0030574 23471 FUN_019407 13 262 338 121 272 NA NA NA NA NA NA NA 23472 FUN_030089 0 117 0 0 4 NA NA NA NA NA NA NA 23473 FUN_044356 122 0 74 107 301 NA NA NA NA NA NA NA 23474 FUN_044357 22 0 10 14 5 NA NA NA NA NA NA NA 23475 FUN_001878 5309 3803 1579 3019 2519 NA NA NA NA NA NA NA 23476 FUN_001879 1285 674 595 1445 955 NA NA NA NA NA NA NA 23477 FUN_001874 0 29 16 0 16 NA NA NA NA NA NA NA 23478 FUN_001875 3 74 32 24 64 NA NA NA NA NA NA NA 23479 FUN_001873 57 641 350 842 611 NA NA NA NA NA NA NA 23480 FUN_001870 0 10 0 0 0 NA NA NA NA NA NA NA 23481 FUN_035567 0 49 0 11 19 NA NA NA NA NA NA NA 23482 FUN_035566 416 333 82 287 136 NA NA NA NA NA NA NA 23483 FUN_035564 116 42 0 100 0 NA NA NA NA NA NA NA 23484 FUN_035563 0 98 0 0 0 NA NA NA NA NA NA NA 23485 FUN_035562 0 46 0 0 0 NA NA NA NA NA NA NA 23486 FUN_035561 138 306 46 349 48 ptg000025l:9122155-9158641 P04146 1.18e-107 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 23487 FUN_035561 138 306 46 349 48 ptg000025l:9122155-9158641 P04146 1.18e-107 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 23488 FUN_035561 138 306 46 349 48 ptg000025l:9122155-9158641 P04146 7.72e-75 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 23489 FUN_035561 138 306 46 349 48 ptg000025l:9122155-9158641 P04146 7.72e-75 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 23490 FUN_035561 138 306 46 349 48 ptg000025l:9122155-9158641 P04146 7.72e-75 Copia protein (Gag-int-pol protein) [Cleaved into: Copia VLP protein; Copia protease (EC 3.4.23.-)] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0004190; GO:0005524; GO:0006508; GO:0008270; GO:0015074; GO:0042575 23491 FUN_035569 1210 807 652 1205 1789 ptg000025l:9237730-9241996 Q96JB1 3.45e-77 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 23492 FUN_035568 35 99 21 108 172 NA NA NA NA NA NA NA 23493 FUN_031026 0 12 0 0 18 NA NA NA NA NA NA NA 23494 FUN_036036 156 143 145 350 146 ptg000025l:14744781-14745450 Q923S9 4.22e-59 Ras-related protein Rab-30 Mus musculus (Mouse) Golgi organization [GO:0007030]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005801; GO:0005802; GO:0007030; GO:0016020; GO:0016192; GO:0031985; GO:0032482; GO:0043231 23495 FUN_036030 1521 1225 998 1612 1174 ptg000025l:14671131-14674176 Q8N2U9 1.92e-21 Solute carrier family 66 member 2 (PQ-loop repeat-containing protein 1) Homo sapiens (Human) phospholipid translocation [GO:0045332]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005802; GO:0005829; GO:0016020; GO:0042147; GO:0045332 23496 FUN_036031 469 213 204 160 174 NA NA NA NA NA NA NA 23497 FUN_036033 0 14 27 19 52 NA NA NA NA NA NA NA 23498 FUN_036038 290 42 17 53 31 ptg000025l:14760193-14774466 O42430 5.35e-83 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 23499 FUN_036038 290 42 17 53 31 ptg000025l:14760193-14774466 O42430 8.55e-80 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 23500 FUN_036038 290 42 17 53 31 ptg000025l:14760193-14774466 O42430 6.19e-60 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 23501 FUN_036039 73 33 80 48 55 ptg000025l:14777879-14782363 O42430 3.23e-87 Cytochrome P450 1A1 (EC 1.14.14.1) (CYPIA1) Limanda limanda (Common dab) (Pleuronectes limanda) NA GO:0005506; GO:0005789; GO:0020037; GO:0070330 23502 FUN_031028 19 0 19 0 41 NA NA NA NA NA NA NA 23503 FUN_031029 0 0 53 2 71 NA NA NA NA NA NA NA 23504 FUN_039614 0 12 0 0 46 NA NA NA NA NA NA NA 23505 FUN_039611 0 0 12 0 44 NA NA NA NA NA NA NA 23506 FUN_007332 7512 8566 3608 4796 3891 ptg000002l:1405197-1430544 Q9QUM9 7.2e-26 Proteasome subunit alpha type-6 (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) Mus musculus (Mouse) positive regulation of NF-kappaB transcription factor activity [GO:0051092]; proteasomal protein catabolic process [GO:0010498]; proteolysis involved in protein catabolic process [GO:0051603]; skeletal muscle tissue development [GO:0007519]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000502; GO:0000932; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005839; GO:0005844; GO:0006511; GO:0007519; GO:0010498; GO:0016363; GO:0019773; GO:0030016; GO:0030017; GO:0051059; GO:0051092; GO:0051603 23507 FUN_007331 0 0 0 0 7 NA NA NA NA NA NA NA 23508 FUN_039612 0 0 0 0 25 NA NA NA NA NA NA NA 23509 FUN_007338 2024 2236 1055 2120 1796 NA NA NA NA NA NA NA 23510 FUN_027653 139 43 0 144 89 NA NA NA NA NA NA NA 23511 FUN_027658 1 0 8 0 41 NA NA NA NA NA NA NA 23512 FUN_013027 5050 2228 2304 4440 3181 NA NA NA NA NA NA NA 23513 FUN_043067 105 59 29 116 72 ptg000047l:3652187-3656072 Q96AY4 3.03e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23514 FUN_043067 105 59 29 116 72 ptg000047l:3652187-3656072 Q96AY4 8.06e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23515 FUN_043067 105 59 29 116 72 ptg000047l:3652187-3656072 Q96AY4 1.42e-101 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23516 FUN_043067 105 59 29 116 72 ptg000047l:3652187-3656072 Q96AY4 2.3e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23517 FUN_043067 105 59 29 116 72 ptg000047l:3652187-3656072 Q96AY4 3.74e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23518 FUN_043067 105 59 29 116 72 ptg000047l:3652187-3656072 Q96AY4 5.77e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23519 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23520 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 1.11e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23521 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 2.5e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23522 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 3.34e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23523 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 5.55e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23524 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 5.88e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23525 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 6.91e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23526 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 5.81e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23527 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 4.34e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23528 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 1.48e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23529 FUN_043066 124 149 35 201 64 ptg000047l:3633342-3638855 Q96AY4 1.43e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23530 FUN_006064 11 11 16 2 18 NA NA NA NA NA NA NA 23531 FUN_006060 0 19 4 0 8 NA NA NA NA NA NA NA 23532 FUN_006063 347 439 196 140 287 NA NA NA NA NA NA NA 23533 FUN_006068 93 95 53 74 81 NA NA NA NA NA NA NA 23534 FUN_043064 0 0 0 0 22 NA NA NA NA NA NA NA 23535 FUN_037079 3035 2413 1619 1964 1317 ptg000026l:5442155-5454711 Q2T9P5 5.95e-28 Cell cycle control protein 50C (Transmembrane protein 30C) Bos taurus (Bovine) phospholipid translocation [GO:0045332] GO:0005783; GO:0005794; GO:0005886; GO:0045332 23536 FUN_037078 886 574 329 631 514 ptg000026l:5435850-5438424 A7SVT1 0 Protein adenylyltransferase Fic (EC 2.7.7.108) (De-AMPylase Fic) (EC 3.1.4.-) Nematostella vectensis (Starlet sea anemone) NA GO:0005524; GO:0016020; GO:0016787; GO:0070733 23537 FUN_037077 3582 2968 1659 2712 2407 NA NA NA NA NA NA NA 23538 FUN_037076 326 310 358 379 459 ptg000026l:5397180-5407091 Q6DEW6 2.18e-22 RNA exonuclease 4 (EC 3.1.-.-) (Exonuclease XPMC2) (Prevents mitotic catastrophe 2 protein) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) rRNA processing [GO:0006364] GO:0003676; GO:0005634; GO:0006364; GO:0008408 23539 FUN_037075 1746 1327 885 1629 1194 NA NA NA NA NA NA NA 23540 FUN_037074 32 60 78 179 18 NA NA NA NA NA NA NA 23541 FUN_037073 315 201 293 369 189 NA NA NA NA NA NA NA 23542 FUN_037072 502 278 425 313 415 NA NA NA NA NA NA NA 23543 FUN_037071 5466 4865 3588 7769 4959 NA NA NA NA NA NA NA 23544 FUN_037070 850 357 300 782 497 NA NA NA NA NA NA NA 23545 FUN_032647 55 14 54 58 31 NA NA NA NA NA NA NA 23546 FUN_032646 0 19 0 10 0 NA NA NA NA NA NA NA 23547 FUN_032645 56 111 167 418 107 NA NA NA NA NA NA NA 23548 FUN_032644 37 74 52 62 80 ptg000023l:34478340-34481451 Q54T82 1.16e-43 Putative leucine-rich repeat-containing protein DDB_G0281931 Dictyostelium discoideum (Social amoeba) NA GO:0016020 23549 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 9.21e-39 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23550 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 4.1e-31 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23551 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 5.47e-30 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23552 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 2.17e-29 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23553 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 3.62e-29 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23554 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 3.84e-29 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23555 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 4.24e-29 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23556 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 5.48e-28 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23557 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 4.58e-27 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23558 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 2.2e-25 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23559 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 1.49e-24 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23560 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 6.29e-24 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23561 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 1.16e-23 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23562 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 1.2e-23 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23563 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 4.08e-22 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23564 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 6.18e-21 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23565 FUN_032641 610 569 623 1026 966 ptg000023l:34218709-34264350 Q2PZL6 7.12e-21 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 23566 FUN_032640 64 31 6 65 62 NA NA NA NA NA NA NA 23567 FUN_032649 133 187 220 194 339 NA NA NA NA NA NA NA 23568 FUN_032648 1173 467 383 399 1233 NA NA NA NA NA NA NA 23569 FUN_002634 103 1 26 0 182 NA NA NA NA NA NA NA 23570 FUN_002638 139 689 54 386 91 NA NA NA NA NA NA NA 23571 FUN_008254 130 136 49 12 23 NA NA NA NA NA NA NA 23572 FUN_030869 40 40 147 52 69 NA NA NA NA NA NA NA 23573 FUN_030861 0 0 108 2 0 NA NA NA NA NA NA NA 23574 FUN_030860 10 78 23 14 37 NA NA NA NA NA NA NA 23575 FUN_030862 0 0 36 0 0 NA NA NA NA NA NA NA 23576 FUN_030866 0 52 0 0 0 NA NA NA NA NA NA NA 23577 FUN_001595 284 133 103 392 848 NA NA NA NA NA NA NA 23578 FUN_001594 9034 4842 3771 6206 1886 NA NA NA NA NA NA NA 23579 FUN_001597 16 0 16 0 40 NA NA NA NA NA NA NA 23580 FUN_001591 6631 4412 2928 7147 4794 NA NA NA NA NA NA NA 23581 FUN_001590 249 178 183 263 297 NA NA NA NA NA NA NA 23582 FUN_001593 3481 1922 1466 4074 3179 NA NA NA NA NA NA NA 23583 FUN_004519 20 12 0 18 0 ntLink_8:24004046-24005746 P17971 1.26e-107 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 23584 FUN_004516 147 162 138 202 134 NA NA NA NA NA NA NA 23585 FUN_004517 1121 417 439 1858 1017 NA NA NA NA NA NA NA 23586 FUN_004514 2686 1643 1399 2304 2203 NA NA NA NA NA NA NA 23587 FUN_004515 9693 6102 5064 7731 7266 NA NA NA NA NA NA NA 23588 FUN_001599 1990 1769 1099 1764 1636 NA NA NA NA NA NA NA 23589 FUN_004513 241 194 174 492 348 NA NA NA NA NA NA NA 23590 FUN_004510 591 383 226 499 348 ntLink_8:23881267-23882703 Q8VDU0 1.13e-27 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 23591 FUN_004511 2873 2389 1403 2681 1991 NA NA NA NA NA NA NA 23592 FUN_005036 32 13 6 55 53 ntLink_8:30309722-30313738 Q64732 2.07e-55 Forkhead box protein B1 (Transcription factor FKH-5) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; axon target recognition [GO:0007412]; cell differentiation [GO:0030154]; cell migration in diencephalon [GO:0061381]; epithelial cell differentiation involved in mammary gland alveolus development [GO:0061030]; floor plate development [GO:0033504]; hypothalamus cell migration [GO:0021855]; inferior colliculus development [GO:0061379]; lactation [GO:0007595]; mammary gland lobule development [GO:0061377]; mammillary body development [GO:0021767]; mammillothalamic axonal tract development [GO:0061374]; midbrain development [GO:0030901]; negative regulation of neuron apoptotic process [GO:0043524]; regulation of transcription by RNA polymerase II [GO:0006357]; somitogenesis [GO:0001756]; spinal cord development [GO:0021510]; telencephalon cell migration [GO:0022029]; thalamus development [GO:0021794]; urogenital system development [GO:0001655]; visual learning [GO:0008542] GO:0000978; GO:0000981; GO:0001655; GO:0001756; GO:0005634; GO:0006357; GO:0007412; GO:0007595; GO:0008542; GO:0009653; GO:0021510; GO:0021767; GO:0021794; GO:0021855; GO:0022029; GO:0030154; GO:0030901; GO:0033504; GO:0043524; GO:0043565; GO:0061030; GO:0061374; GO:0061377; GO:0061379; GO:0061381; GO:1990837 23593 FUN_001049 1644 1731 951 1637 983 ntLink_6:7886174-7890422 P28039 3.59e-62 Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit] Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; lipopolysaccharide catabolic process [GO:0009104]; negative regulation of inflammatory response [GO:0050728] GO:0005509; GO:0005576; GO:0006631; GO:0009104; GO:0031410; GO:0043231; GO:0050528; GO:0050728 23594 FUN_001049 1644 1731 951 1637 983 ntLink_6:7886174-7890422 P28039 1.13e-29 Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit] Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; lipopolysaccharide catabolic process [GO:0009104]; negative regulation of inflammatory response [GO:0050728] GO:0005509; GO:0005576; GO:0006631; GO:0009104; GO:0031410; GO:0043231; GO:0050528; GO:0050728 23595 FUN_000005 92 302 129 258 629 NA NA NA NA NA NA NA 23596 FUN_001047 62 0 27 11 26 NA NA NA NA NA NA NA 23597 FUN_001046 106 153 98 104 70 NA NA NA NA NA NA NA 23598 FUN_001045 154 24 0 24 74 NA NA NA NA NA NA NA 23599 FUN_001044 319 148 67 40 145 NA NA NA NA NA NA NA 23600 FUN_001043 49 59 77 9 90 NA NA NA NA NA NA NA 23601 FUN_000006 11 62 21 31 200 NA NA NA NA NA NA NA 23602 FUN_001041 2243 1769 1127 2314 1442 NA NA NA NA NA NA NA 23603 FUN_001040 3555 2663 455 1827 1167 ntLink_6:7563562-7571096 P80035 9.6e-29 Gastric triacylglycerol lipase (GL) (Gastric lipase) (EC 3.1.1.3) Canis lupus familiaris (Dog) (Canis familiaris) lipid catabolic process [GO:0016042] GO:0004806; GO:0005576; GO:0016042; GO:0043231 23604 FUN_033514 3 0 106 0 0 NA NA NA NA NA NA NA 23605 FUN_033510 3764 1462 1855 2774 2466 NA NA NA NA NA NA NA 23606 FUN_033511 150 69 82 90 159 NA NA NA NA NA NA NA 23607 FUN_033512 475 0 78 6 195 NA NA NA NA NA NA NA 23608 FUN_042031 22 21 0 16 69 NA NA NA NA NA NA NA 23609 FUN_033519 2 15 12 10 3 NA NA NA NA NA NA NA 23610 FUN_000001 6 5 27 6 194 NA NA NA NA NA NA NA 23611 FUN_002586 81 5 963 104 23 NA NA NA NA NA NA NA 23612 FUN_002585 2375 966 349 778 125 NA NA NA NA NA NA NA 23613 FUN_002584 939 328 328 575 579 ntLink_8:4014044-4088104 Q95SX7 8.92e-23 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 23614 FUN_002583 35 28 38 21 64 NA NA NA NA NA NA NA 23615 FUN_000002 96 239 175 278 637 NA NA NA NA NA NA NA 23616 FUN_002581 413 313 318 394 325 ntLink_8:3991231-3998070 A9V7A1 1.66e-25 Cytosolic Fe-S cluster assembly factor NUBP2 homolog Monosiga brevicollis (Choanoflagellate) iron-sulfur cluster assembly [GO:0016226] GO:0005524; GO:0005829; GO:0016226; GO:0046872; GO:0051536; GO:0051539; GO:0140663 23617 FUN_002580 2284 2940 1769 2982 2812 ntLink_8:3977316-3990226 A8MY62 2.27e-54 Putative beta-lactamase-like 1 Homo sapiens (Human) NA NA 23618 FUN_041092 0 0 0 0 6 NA NA NA NA NA NA NA 23619 FUN_044301 0 0 0 40 0 NA NA NA NA NA NA NA 23620 FUN_035918 17 19 7 37 102 NA NA NA NA NA NA NA 23621 FUN_035919 0 27 0 0 0 NA NA NA NA NA NA NA 23622 FUN_035916 352 204 224 699 576 NA NA NA NA NA NA NA 23623 FUN_035917 1587 916 475 807 651 NA NA NA NA NA NA NA 23624 FUN_035914 405 84 217 288 413 NA NA NA NA NA NA NA 23625 FUN_035912 71 140 33 65 21 NA NA NA NA NA NA NA 23626 FUN_035913 1160 636 284 574 539 NA NA NA NA NA NA NA 23627 FUN_035910 3585 3248 976 2010 2129 NA NA NA NA NA NA NA 23628 FUN_035911 2188 1094 429 947 669 NA NA NA NA NA NA NA 23629 FUN_041266 6 3 5 18 5 NA NA NA NA NA NA NA 23630 FUN_038200 41 44 18 186 70 NA NA NA NA NA NA NA 23631 FUN_018418 1505 62 122 145 42 NA NA NA NA NA NA NA 23632 FUN_018412 20012 5202 9679 12660 3454 NA NA NA NA NA NA NA 23633 FUN_018413 64 52 52 152 42 NA NA NA NA NA NA NA 23634 FUN_018410 29 44 36 203 625 NA NA NA NA NA NA NA 23635 FUN_018411 3 1057 0 9 1414 NA NA NA NA NA NA NA 23636 FUN_018416 442 101 81 146 271 NA NA NA NA NA NA NA 23637 FUN_018417 95 30 0 117 0 NA NA NA NA NA NA NA 23638 FUN_018414 3334 2663 1739 2964 3012 NA NA NA NA NA NA NA 23639 FUN_018415 1760 2983 1045 1111 1108 NA NA NA NA NA NA NA 23640 FUN_012450 166 94 94 39 22 NA NA NA NA NA NA NA 23641 FUN_012452 0 0 0 0 21 NA NA NA NA NA NA NA 23642 FUN_012453 0 0 0 6 0 NA NA NA NA NA NA NA 23643 FUN_012454 19 119 17 60 78 NA NA NA NA NA NA NA 23644 FUN_012455 0 468 206 172 226 NA NA NA NA NA NA NA 23645 FUN_012456 416 28 129 176 155 NA NA NA NA NA NA NA 23646 FUN_012457 21 2909 37 4644 4627 ptg000008l:9088295-9106011 A0A0A2JW91 5.48e-137 Highly reducing polyketide synthase cnsI (EC 2.3.1.-) (Communesin biosynthesis cluster protein I) Penicillium expansum (Blue mold rot fungus) fatty acid biosynthetic process [GO:0006633]; heterocycle metabolic process [GO:0046483]; organic cyclic compound metabolic process [GO:1901360]; secondary metabolite biosynthetic process [GO:0044550] GO:0004315; GO:0006633; GO:0016491; GO:0031177; GO:0044550; GO:0046483; GO:1901360 23647 FUN_012458 0 90 0 73 59 NA NA NA NA NA NA NA 23648 FUN_012459 101 6 20 0 106 NA NA NA NA NA NA NA 23649 FUN_006805 455 462 207 408 194 NA NA NA NA NA NA NA 23650 FUN_006802 4087 1331 1259 1462 1138 ptg000001l:16816485-16826361 Q6ITT3 5.24e-56 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 23651 FUN_016525 129 57 44 115 62 ptg000011l:4358361-4362877 Q96AY4 2.46e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23652 FUN_016525 129 57 44 115 62 ptg000011l:4358361-4362877 Q96AY4 1.6e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23653 FUN_016525 129 57 44 115 62 ptg000011l:4358361-4362877 Q96AY4 5.44e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23654 FUN_016525 129 57 44 115 62 ptg000011l:4358361-4362877 Q96AY4 2.05e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23655 FUN_016525 129 57 44 115 62 ptg000011l:4358361-4362877 Q96AY4 6.95e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23656 FUN_016525 129 57 44 115 62 ptg000011l:4358361-4362877 Q96AY4 3.99e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23657 FUN_006800 4 211 207 1635 4 NA NA NA NA NA NA NA 23658 FUN_006801 4098 3314 3178 4585 3477 ptg000001l:16784422-16807274 Q9XT50 3.65e-51 Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein homolog) Ovis aries (Sheep) copper ion transport [GO:0006825]; regulation of biological quality [GO:0065008] GO:0005507; GO:0005524; GO:0005770; GO:0006825; GO:0016887; GO:0032588; GO:0043682; GO:0065008; GO:0140581 23659 FUN_006801 4098 3314 3178 4585 3477 ptg000001l:16784422-16807274 Q9XT50 2.96e-43 Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein homolog) Ovis aries (Sheep) copper ion transport [GO:0006825]; regulation of biological quality [GO:0065008] GO:0005507; GO:0005524; GO:0005770; GO:0006825; GO:0016887; GO:0032588; GO:0043682; GO:0065008; GO:0140581 23660 FUN_006801 4098 3314 3178 4585 3477 ptg000001l:16784422-16807274 Q9XT50 1.31e-30 Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein homolog) Ovis aries (Sheep) copper ion transport [GO:0006825]; regulation of biological quality [GO:0065008] GO:0005507; GO:0005524; GO:0005770; GO:0006825; GO:0016887; GO:0032588; GO:0043682; GO:0065008; GO:0140581 23661 FUN_006801 4098 3314 3178 4585 3477 ptg000001l:16784422-16807274 Q9XT50 4.13e-23 Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein homolog) Ovis aries (Sheep) copper ion transport [GO:0006825]; regulation of biological quality [GO:0065008] GO:0005507; GO:0005524; GO:0005770; GO:0006825; GO:0016887; GO:0032588; GO:0043682; GO:0065008; GO:0140581 23662 FUN_006801 4098 3314 3178 4585 3477 ptg000001l:16784422-16807274 Q9XT50 2.52e-22 Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein homolog) Ovis aries (Sheep) copper ion transport [GO:0006825]; regulation of biological quality [GO:0065008] GO:0005507; GO:0005524; GO:0005770; GO:0006825; GO:0016887; GO:0032588; GO:0043682; GO:0065008; GO:0140581 23663 FUN_006801 4098 3314 3178 4585 3477 ptg000001l:16784422-16807274 Q9XT50 2.72e-22 Copper-transporting ATPase 2 (EC 7.2.2.8) (Copper pump 2) (Wilson disease-associated protein homolog) Ovis aries (Sheep) copper ion transport [GO:0006825]; regulation of biological quality [GO:0065008] GO:0005507; GO:0005524; GO:0005770; GO:0006825; GO:0016887; GO:0032588; GO:0043682; GO:0065008; GO:0140581 23664 FUN_016529 37 334 8 16 140 NA NA NA NA NA NA NA 23665 FUN_006809 33 89 42 156 71 NA NA NA NA NA NA NA 23666 FUN_035008 507 191 178 213 258 NA NA NA NA NA NA NA 23667 FUN_035009 2469 1720 975 1171 1337 NA NA NA NA NA NA NA 23668 FUN_035004 1762 1584 530 1591 896 NA NA NA NA NA NA NA 23669 FUN_035005 127 112 105 195 87 NA NA NA NA NA NA NA 23670 FUN_035006 6024 5920 3604 5656 3497 NA NA NA NA NA NA NA 23671 FUN_035007 2619 2188 1371 2374 1660 NA NA NA NA NA NA NA 23672 FUN_035000 0 0 0 21 12 NA NA NA NA NA NA NA 23673 FUN_035001 1094 1999 1080 1213 1735 NA NA NA NA NA NA NA 23674 FUN_035002 1924 3305 1158 1294 1324 NA NA NA NA NA NA NA 23675 FUN_035003 0 0 8 0 7 ptg000025l:2673011-2676049 P23819 3.86e-112 Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2) (GluA2) Mus musculus (Mouse) cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; cellular response to glycine [GO:1905430]; chemical synaptic transmission [GO:0007268]; establishment of protein localization [GO:0045184]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of synaptic transmission [GO:0050806]; protein tetramerization [GO:0051262]; receptor internalization [GO:0031623]; regulation of receptor recycling [GO:0001919]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0000149; GO:0001540; GO:0001919; GO:0004970; GO:0004971; GO:0005234; GO:0005783; GO:0005789; GO:0005886; GO:0007268; GO:0008021; GO:0008092; GO:0009986; GO:0014069; GO:0015276; GO:0015277; GO:0016020; GO:0019865; GO:0019901; GO:0030165; GO:0030424; GO:0030425; GO:0030426; GO:0030672; GO:0031623; GO:0032279; GO:0032281; GO:0032590; GO:0032839; GO:0032991; GO:0035235; GO:0035254; GO:0035255; GO:0036477; GO:0038023; GO:0042734; GO:0042802; GO:0043005; GO:0043025; GO:0043195; GO:0043197; GO:0043198; GO:0043204; GO:0044326; GO:0044327; GO:0044877; GO:0045184; GO:0045202; GO:0045211; GO:0048787; GO:0050806; GO:0051117; GO:0051262; GO:0051966; GO:0097060; GO:0097110; GO:0098685; GO:0098793; GO:0098839; GO:0098978; GO:0099507; GO:0099544; GO:0106033; GO:1904315; GO:1905430; GO:1990416 23676 FUN_028138 661 1222 353 917 481 ptg000021l:16120498-16127663 Q6DRI7 3.3e-47 ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51) Danio rerio (Zebrafish) (Brachydanio rerio) rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0006364; GO:0016887 23677 FUN_028138 661 1222 353 917 481 ptg000021l:16120498-16127663 Q6DRI7 2.57e-26 ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51) Danio rerio (Zebrafish) (Brachydanio rerio) rRNA processing [GO:0006364] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005730; GO:0006364; GO:0016887 23678 FUN_028139 2236 2679 1950 3067 1330 NA NA NA NA NA NA NA 23679 FUN_003355 0 0 15 0 1 NA NA NA NA NA NA NA 23680 FUN_003354 3 0 5 0 15 NA NA NA NA NA NA NA 23681 FUN_028134 254 97 30 92 52 NA NA NA NA NA NA NA 23682 FUN_028135 3333 2060 2036 2816 2288 ptg000021l:16085559-16097230 P48444 7.39e-35 Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; cerebellar Purkinje cell layer maturation [GO:0021691]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi localization [GO:0051645]; intracellular protein transport [GO:0006886]; pigmentation [GO:0043473]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0003723; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0008344; GO:0016020; GO:0021691; GO:0030126; GO:0030133; GO:0043473; GO:0051645 23683 FUN_028135 3333 2060 2036 2816 2288 ptg000021l:16085559-16097230 P48444 7.13e-23 Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP) Homo sapiens (Human) adult locomotory behavior [GO:0008344]; cerebellar Purkinje cell layer maturation [GO:0021691]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi localization [GO:0051645]; intracellular protein transport [GO:0006886]; pigmentation [GO:0043473]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0003723; GO:0005789; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0008344; GO:0016020; GO:0021691; GO:0030126; GO:0030133; GO:0043473; GO:0051645 23684 FUN_028132 135 78 262 55 198 NA NA NA NA NA NA NA 23685 FUN_003353 19 0 14 0 75 NA NA NA NA NA NA NA 23686 FUN_003352 17 0 8 0 80 NA NA NA NA NA NA NA 23687 FUN_028680 5 73 14 30 31 NA NA NA NA NA NA NA 23688 FUN_041242 20 9 5 30 2 NA NA NA NA NA NA NA 23689 FUN_028685 0 14 0 0 0 NA NA NA NA NA NA NA 23690 FUN_028687 23 12 0 13 2 ptg000022l:2647212-2657292 Q96AY4 3.57e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23691 FUN_028687 23 12 0 13 2 ptg000022l:2647212-2657292 Q96AY4 3.65e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23692 FUN_028687 23 12 0 13 2 ptg000022l:2647212-2657292 Q96AY4 7.61e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23693 FUN_028687 23 12 0 13 2 ptg000022l:2647212-2657292 Q96AY4 1.62e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23694 FUN_028687 23 12 0 13 2 ptg000022l:2647212-2657292 Q96AY4 1.58e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23695 FUN_013328 268 170 585 287 568 NA NA NA NA NA NA NA 23696 FUN_011699 30565 34078 13445 24234 23363 ptg000008l:334029-338524 P55832 2.77e-24 40S ribosomal protein S4 Equus caballus (Horse) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0019843; GO:0022627 23697 FUN_011699 30565 34078 13445 24234 23363 ptg000008l:334029-338524 P55832 1.58e-23 40S ribosomal protein S4 Equus caballus (Horse) translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0019843; GO:0022627 23698 FUN_003979 215 84 81 234 340 NA NA NA NA NA NA NA 23699 FUN_003978 102 111 95 4 189 ntLink_8:17646246-17648775 Q8VIG3 1.98e-40 Radial spoke head 1 homolog (Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein) Mus musculus (Mouse) axoneme assembly [GO:0035082]; meiotic cell cycle [GO:0051321]; spermatid development [GO:0007286] GO:0000794; GO:0001520; GO:0005634; GO:0005737; GO:0005829; GO:0005929; GO:0007286; GO:0031514; GO:0035082; GO:0036126; GO:0051321; GO:0072687 23700 FUN_003970 0 0 12 0 0 NA NA NA NA NA NA NA 23701 FUN_003973 37 27 0 29 33 NA NA NA NA NA NA NA 23702 FUN_003972 16 0 0 0 4 NA NA NA NA NA NA NA 23703 FUN_003975 0 0 0 0 10 NA NA NA NA NA NA NA 23704 FUN_003974 21 0 0 8 35 NA NA NA NA NA NA NA 23705 FUN_003977 56 50 37 111 114 NA NA NA NA NA NA NA 23706 FUN_003976 22 0 16 0 32 NA NA NA NA NA NA NA 23707 FUN_021608 899 624 384 886 824 NA NA NA NA NA NA NA 23708 FUN_009050 0 85 0 63 107 NA NA NA NA NA NA NA 23709 FUN_002003 31 7 33 2 2986 NA NA NA NA NA NA NA 23710 FUN_009053 1712 1144 756 1115 951 NA NA NA NA NA NA NA 23711 FUN_009055 15415 19108 9784 12323 15744 NA NA NA NA NA NA NA 23712 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23713 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23714 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23715 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23716 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 1.66e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23717 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 2.88e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23718 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 1.73e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23719 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 2.67e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23720 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 3.49e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23721 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 7.67e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23722 FUN_009058 81 61 13 16 10 ptg000004l:2228688-2236851 Q96AY4 9.06e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23723 FUN_009059 18 11 13 6 2 NA NA NA NA NA NA NA 23724 FUN_040598 0 0 19 0 0 NA NA NA NA NA NA NA 23725 FUN_025599 5434 3264 2558 4169 4517 NA NA NA NA NA NA NA 23726 FUN_040628 0 0 29 0 0 NA NA NA NA NA NA NA 23727 FUN_015449 698 122 149 328 391 NA NA NA NA NA NA NA 23728 FUN_010142 29 26 40 30 663 NA NA NA NA NA NA NA 23729 FUN_015442 3106 2303 2142 3529 2452 ptg000009l:10199927-10224233 Q8UVK2 8.44e-44 Transcription elongation factor SPT6 (Protein pandora) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic heart tube development [GO:0035050]; heart development [GO:0007507]; mRNA transcription by RNA polymerase II [GO:0042789]; nucleosome organization [GO:0034728]; otic vesicle development [GO:0071599]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; somitogenesis [GO:0001756]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0001756; GO:0003677; GO:0006368; GO:0007507; GO:0008023; GO:0031491; GO:0032968; GO:0034728; GO:0035050; GO:0042393; GO:0042789; GO:0071599; GO:0140673 23730 FUN_015442 3106 2303 2142 3529 2452 ptg000009l:10199927-10224233 Q8UVK2 1.91e-32 Transcription elongation factor SPT6 (Protein pandora) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic heart tube development [GO:0035050]; heart development [GO:0007507]; mRNA transcription by RNA polymerase II [GO:0042789]; nucleosome organization [GO:0034728]; otic vesicle development [GO:0071599]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; somitogenesis [GO:0001756]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0001756; GO:0003677; GO:0006368; GO:0007507; GO:0008023; GO:0031491; GO:0032968; GO:0034728; GO:0035050; GO:0042393; GO:0042789; GO:0071599; GO:0140673 23731 FUN_015442 3106 2303 2142 3529 2452 ptg000009l:10199927-10224233 Q8UVK2 1.3e-28 Transcription elongation factor SPT6 (Protein pandora) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic heart tube development [GO:0035050]; heart development [GO:0007507]; mRNA transcription by RNA polymerase II [GO:0042789]; nucleosome organization [GO:0034728]; otic vesicle development [GO:0071599]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; somitogenesis [GO:0001756]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0001756; GO:0003677; GO:0006368; GO:0007507; GO:0008023; GO:0031491; GO:0032968; GO:0034728; GO:0035050; GO:0042393; GO:0042789; GO:0071599; GO:0140673 23732 FUN_011899 1317 954 905 770 862 NA NA NA NA NA NA NA 23733 FUN_011898 64 0 0 0 0 ptg000008l:2631611-2637153 Q9H0C3 4.5e-39 Transmembrane protein 117 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 23734 FUN_011898 64 0 0 0 0 ptg000008l:2631611-2637153 Q9H0C3 4.44e-38 Transmembrane protein 117 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 23735 FUN_011898 64 0 0 0 0 ptg000008l:2631611-2637153 Q9H0C3 7.01e-30 Transmembrane protein 117 Homo sapiens (Human) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059] GO:0005783; GO:0005886; GO:0070059 23736 FUN_025592 0 0 0 0 72 NA NA NA NA NA NA NA 23737 FUN_011895 44 0 54 25 43 NA NA NA NA NA NA NA 23738 FUN_011894 1834 759 1008 1830 1791 NA NA NA NA NA NA NA 23739 FUN_011897 0 0 0 0 6 NA NA NA NA NA NA NA 23740 FUN_011896 10739 11627 693 20435 3329 NA NA NA NA NA NA NA 23741 FUN_011891 39 2 118 4 29 NA NA NA NA NA NA NA 23742 FUN_011890 2187 396 1429 1497 1499 NA NA NA NA NA NA NA 23743 FUN_011893 2410 1139 1358 2129 2435 NA NA NA NA NA NA NA 23744 FUN_011892 1846 1062 643 1267 1314 ptg000008l:2544605-2564491 E1C231 2.08e-26 E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (Zfp-294) (RING-type E3 ubiquitin transferase listerin) Gallus gallus (Chicken) rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005829; GO:0008270; GO:0043023; GO:0061630; GO:0072344; GO:1990112; GO:1990116 23745 FUN_011892 1846 1062 643 1267 1314 ptg000008l:2544605-2564491 E1C231 8.65e-23 E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (Zfp-294) (RING-type E3 ubiquitin transferase listerin) Gallus gallus (Chicken) rescue of stalled ribosome [GO:0072344]; ribosome-associated ubiquitin-dependent protein catabolic process [GO:1990116] GO:0005829; GO:0008270; GO:0043023; GO:0061630; GO:0072344; GO:1990112; GO:1990116 23746 FUN_025590 124 34 29 61 25 NA NA NA NA NA NA NA 23747 FUN_015447 227 266 258 307 178 ptg000009l:10277992-10285541 P35680 2.53e-23 Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1) Homo sapiens (Human) anterior/posterior pattern specification [GO:0009952]; branching morphogenesis of an epithelial tube [GO:0048754]; circadian regulation of gene expression [GO:0032922]; embryonic digestive tract morphogenesis [GO:0048557]; endocrine pancreas development [GO:0031018]; endodermal cell fate specification [GO:0001714]; epithelial cell proliferation [GO:0050673]; genitalia development [GO:0048806]; hepatoblast differentiation [GO:0061017]; hepatocyte differentiation [GO:0070365]; hindbrain development [GO:0030902]; inner cell mass cell differentiation [GO:0001826]; insulin secretion [GO:0030073]; kidney development [GO:0001822]; mesenchymal cell apoptotic process involved in metanephros development [GO:1900200]; mesonephric duct formation [GO:0072181]; negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis [GO:0061296]; negative regulation of mesenchymal cell apoptotic process involved in metanephros development [GO:1900212]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of transcription initiation by RNA polymerase II [GO:0060261]; pronephric nephron tubule development [GO:0039020]; pronephros development [GO:0048793]; protein-DNA complex assembly [GO:0065004]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of pronephros size [GO:0035565]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to glucose [GO:0009749]; response to organic cyclic compound [GO:0014070]; response to xenobiotic stimulus [GO:0009410]; ureteric bud elongation [GO:0060677] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001221; GO:0001714; GO:0001822; GO:0001826; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0006357; GO:0007219; GO:0009410; GO:0009749; GO:0009952; GO:0010628; GO:0014070; GO:0030073; GO:0030111; GO:0030902; GO:0031016; GO:0031018; GO:0032922; GO:0035565; GO:0039020; GO:0042802; GO:0042803; GO:0043231; GO:0044877; GO:0045893; GO:0048557; GO:0048754; GO:0048793; GO:0048806; GO:0050673; GO:0060261; GO:0060677; GO:0061017; GO:0061296; GO:0065004; GO:0070365; GO:0072095; GO:0072181; GO:1900200; GO:1900212 23748 FUN_009944 1710 1304 602 1150 523 NA NA NA NA NA NA NA 23749 FUN_025595 871 708 912 1078 1261 ptg000019l:4785074-4799206 O54967 3.06e-25 Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2) Mus musculus (Mouse) cell differentiation [GO:0030154]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phosphorylation [GO:0016310]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; regulation of clathrin-dependent endocytosis [GO:2000369]; spermatid development [GO:0007286]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004674; GO:0004712; GO:0004713; GO:0004715; GO:0005102; GO:0005154; GO:0005524; GO:0005634; GO:0005737; GO:0005768; GO:0005829; GO:0005886; GO:0005905; GO:0005912; GO:0006897; GO:0007169; GO:0007286; GO:0016310; GO:0030136; GO:0030154; GO:0030424; GO:0030425; GO:0030426; GO:0030659; GO:0031234; GO:0031625; GO:0042802; GO:0043025; GO:0043231; GO:0045087; GO:0046872; GO:0050699; GO:0050731; GO:0070436; GO:0097268; GO:0106310; GO:2000369 23750 FUN_009940 7 2 0 1 0 NA NA NA NA NA NA NA 23751 FUN_009941 7 1 0 3 1 NA NA NA NA NA NA NA 23752 FUN_015445 923 906 586 1262 660 ptg000009l:10238930-10257931 O75140 3.07e-40 GATOR complex protein DEPDC5 (DEP domain-containing protein 5) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005764; GO:0005765; GO:0005829; GO:0010508; GO:0032007; GO:0034198; GO:0035556; GO:0044877; GO:0048471; GO:1904262; GO:1990130 23753 FUN_015445 923 906 586 1262 660 ptg000009l:10238930-10257931 O75140 3.38e-23 GATOR complex protein DEPDC5 (DEP domain-containing protein 5) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; intracellular signal transduction [GO:0035556]; negative regulation of TOR signaling [GO:0032007]; negative regulation of TORC1 signaling [GO:1904262]; positive regulation of autophagy [GO:0010508] GO:0005096; GO:0005764; GO:0005765; GO:0005829; GO:0010508; GO:0032007; GO:0034198; GO:0035556; GO:0044877; GO:0048471; GO:1904262; GO:1990130 23754 FUN_008099 2558 1400 772 1605 1160 ptg000002l:7996353-8016660 Q8BZ03 1.36e-35 Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; angiogenesis [GO:0001525]; cell adhesion [GO:0007155]; cellular response to vascular endothelial growth factor stimulus [GO:0035924]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of angiogenesis [GO:0045766]; positive regulation of blood vessel endothelial cell migration [GO:0043536]; positive regulation of cell adhesion [GO:0045785]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of endothelial cell chemotaxis [GO:2001028]; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway [GO:0038033]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743]; positive regulation of histone deacetylase activity [GO:1901727]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of intracellular signal transduction [GO:1902533]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of T cell receptor signaling pathway [GO:0050862]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030949]; protein autophosphorylation [GO:0046777]; protein kinase D signaling [GO:0089700]; protein phosphorylation [GO:0006468]; regulation of T cell apoptotic process [GO:0070232]; T cell receptor signaling pathway [GO:0050852]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] GO:0001525; GO:0001938; GO:0002250; GO:0004672; GO:0004674; GO:0004698; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0006468; GO:0007155; GO:0010595; GO:0018105; GO:0018107; GO:0030949; GO:0032743; GO:0032757; GO:0032793; GO:0033138; GO:0035556; GO:0035924; GO:0038033; GO:0043536; GO:0045743; GO:0045766; GO:0045785; GO:0045944; GO:0046777; GO:0046872; GO:0048010; GO:0050852; GO:0050862; GO:0051091; GO:0051092; GO:0070232; GO:0070374; GO:0089700; GO:0106310; GO:1901727; GO:1902533; GO:2000573; GO:2001028 23755 FUN_008098 3808 3266 2549 3856 3106 NA NA NA NA NA NA NA 23756 FUN_041582 4021 2334 2111 2551 1651 NA NA NA NA NA NA NA 23757 FUN_008093 2351 1042 1510 2626 1578 NA NA NA NA NA NA NA 23758 FUN_008092 444 252 330 505 675 NA NA NA NA NA NA NA 23759 FUN_008091 257 171 209 202 204 NA NA NA NA NA NA NA 23760 FUN_008090 2775 1786 1233 2086 2048 ptg000002l:7897810-7919915 A5D7H2 1.49e-22 Striatin-3 Bos taurus (Bovine) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0005516; GO:0005654; GO:0005737; GO:0005794; GO:0005886; GO:0030425; GO:0031267; GO:0044877; GO:0045892; GO:0045944; GO:0051721; GO:0070016; GO:0090443 23761 FUN_008096 40 36 0 36 41 ptg000002l:7975216-7978973 D3YY91 9.24e-33 Leucine-rich repeat protein 1 Mus musculus (Mouse) protein ubiquitination [GO:0016567] GO:0005634; GO:0016567 23762 FUN_004495 2911 1225 842 739 1401 NA NA NA NA NA NA NA 23763 FUN_008094 762 390 385 498 685 NA NA NA NA NA NA NA 23764 FUN_032368 41 21 13 113 41 NA NA NA NA NA NA NA 23765 FUN_032369 34 0 7 34 15 ptg000023l:31240317-31241541 Q92038 1.81e-64 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23766 FUN_032369 34 0 7 34 15 ptg000023l:31240317-31241541 Q92038 7.57e-30 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23767 FUN_032364 643 301 175 117 119 ptg000023l:31203940-31206452 O62849 4.4e-36 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Ovis aries (Sheep) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23768 FUN_032364 643 301 175 117 119 ptg000023l:31203940-31206452 O62849 4.26e-30 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Ovis aries (Sheep) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23769 FUN_032365 1286 713 773 1604 679 ptg000023l:31209171-31210975 Q92038 2.66e-65 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23770 FUN_032365 1286 713 773 1604 679 ptg000023l:31209171-31210975 Q92038 1.65e-37 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23771 FUN_032366 12 2 8 26 59 NA NA NA NA NA NA NA 23772 FUN_032367 77 25 20 69 35 ptg000023l:31219370-31221119 Q92038 5.55e-60 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23773 FUN_032367 77 25 20 69 35 ptg000023l:31219370-31221119 Q92038 1.82e-32 Acyl-CoA desaturase (EC 1.14.19.1) (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase) Cyprinus carpio (Common carp) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0004768; GO:0005506; GO:0005789; GO:0006636; GO:0016020; GO:0016491 23774 FUN_032360 228 129 89 52 69 NA NA NA NA NA NA NA 23775 FUN_032361 699 225 235 520 397 NA NA NA NA NA NA NA 23776 FUN_032363 1762 1264 1334 1555 1153 NA NA NA NA NA NA NA 23777 FUN_028918 332 99 69 147 172 ptg000022l:5941315-5948672 A7RX26 5.88e-26 Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1 homolog) Nematostella vectensis (Starlet sea anemone) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005737; GO:0006548; GO:0019556; GO:0019557; GO:0046872; GO:0050480 23778 FUN_028918 332 99 69 147 172 ptg000022l:5941315-5948672 A7RX26 1.5e-22 Probable imidazolonepropionase (EC 3.5.2.7) (Amidohydrolase domain-containing protein 1 homolog) Nematostella vectensis (Starlet sea anemone) histidine catabolic process [GO:0006548]; histidine catabolic process to glutamate and formamide [GO:0019556]; histidine catabolic process to glutamate and formate [GO:0019557] GO:0005737; GO:0006548; GO:0019556; GO:0019557; GO:0046872; GO:0050480 23779 FUN_028919 546 493 156 551 356 NA NA NA NA NA NA NA 23780 FUN_041583 371 816 671 324 347 NA NA NA NA NA NA NA 23781 FUN_028910 883 885 1171 864 1258 NA NA NA NA NA NA NA 23782 FUN_028911 1460 946 698 1223 845 NA NA NA NA NA NA NA 23783 FUN_028912 960 793 580 694 873 ptg000022l:5880607-5883922 O70279 3.31e-34 Splicing factor ESS-2 homolog (ES2 protein) (Expressed sequence 2 embryonic lethal) Mus musculus (Mouse) mRNA processing [GO:0006397]; nervous system development [GO:0007399]; RNA splicing [GO:0008380] GO:0005634; GO:0006397; GO:0007399; GO:0008380; GO:0071013 23784 FUN_028913 456 344 400 547 419 NA NA NA NA NA NA NA 23785 FUN_028914 663 1032 678 486 291 ptg000022l:5916914-5919613 Q04832 5.1e-28 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 23786 FUN_028914 663 1032 678 486 291 ptg000022l:5916914-5919613 Q04832 5.15e-28 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 23787 FUN_028914 663 1032 678 486 291 ptg000022l:5916914-5919613 Q04832 1.04e-24 DNA-binding protein HEXBP (Hexamer-binding protein) Leishmania major NA GO:0003677; GO:0005634; GO:0008270 23788 FUN_028915 826 923 559 557 415 NA NA NA NA NA NA NA 23789 FUN_028916 0 139 89 124 80 NA NA NA NA NA NA NA 23790 FUN_028917 1190 873 874 1189 1355 NA NA NA NA NA NA NA 23791 FUN_026531 75 181 39 195 226 NA NA NA NA NA NA NA 23792 FUN_011239 241 179 76 31 47 NA NA NA NA NA NA NA 23793 FUN_011238 362 192 41 37 32 NA NA NA NA NA NA NA 23794 FUN_028349 645 54 184 689 331 NA NA NA NA NA NA NA 23795 FUN_011232 0 1227 12 0 45 NA NA NA NA NA NA NA 23796 FUN_011237 0 0 0 0 7 NA NA NA NA NA NA NA 23797 FUN_012766 3795 1723 1706 3343 5743 NA NA NA NA NA NA NA 23798 FUN_041302 3 175 104 2 7 NA NA NA NA NA NA NA 23799 FUN_012768 519 297 89 435 354 ptg000008l:12559062-12563152 A1L1W9 6.31e-28 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 23800 FUN_012769 3146 2193 1146 1897 1528 NA NA NA NA NA NA NA 23801 FUN_039059 0 0 8 0 5 NA NA NA NA NA NA NA 23802 FUN_039051 27 0 0 0 6 NA NA NA NA NA NA NA 23803 FUN_039057 6 0 0 0 2 NA NA NA NA NA NA NA 23804 FUN_039055 0 0 0 0 8 NA NA NA NA NA NA NA 23805 FUN_041584 0 0 0 26 0 ptg000035l:5499762-5504212 P10608 1.66e-31 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Rattus norvegicus (Rat) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adrenergic receptor signaling pathway [GO:0071875]; aging [GO:0007568]; associative learning [GO:0008306]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; cellular response to hypoxia [GO:0071456]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diaphragm contraction [GO:0002086]; diet induced thermogenesis [GO:0002024]; estrous cycle [GO:0044849]; excitatory postsynaptic potential [GO:0060079]; female pregnancy [GO:0007565]; G protein-coupled receptor signaling pathway [GO:0007186]; heat generation [GO:0031649]; liver development [GO:0001889]; liver regeneration [GO:0097421]; negative regulation of angiogenesis [GO:0016525]; negative regulation of inflammatory response [GO:0050728]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of ossification [GO:0030279]; negative regulation of platelet aggregation [GO:0090331]; negative regulation of smooth muscle contraction [GO:0045986]; negative regulation of urine volume [GO:0035811]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of apoptotic process [GO:0043065]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of calcium ion import across plasma membrane [GO:1905665]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of heart contraction [GO:0045823]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of potassium ion transport [GO:0043268]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of skeletal muscle tissue growth [GO:0048633]; positive regulation of sodium ion transport [GO:0010765]; positive regulation of the force of heart contraction by epinephrine [GO:0003059]; positive regulation of transcription by RNA polymerase II [GO:0045944]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; receptor-mediated endocytosis [GO:0006898]; regulation of calcium ion transport [GO:0051924]; regulation of sensory perception of pain [GO:0051930]; regulation of sodium ion transport [GO:0002028]; regulation of systemic arterial blood pressure by norepinephrine-epinephrine [GO:0001993]; response to catecholamine [GO:0071869]; response to cold [GO:0009409]; response to dexamethasone [GO:0071548]; response to estrogen [GO:0043627]; response to hypoxia [GO:0001666]; response to monoamine [GO:0071867]; response to progesterone [GO:0032570]; response to testosterone [GO:0033574]; smooth muscle contraction [GO:0006939]; synaptic transmission, glutamatergic [GO:0035249]; transcription by RNA polymerase II [GO:0006366]; vasodilation [GO:0042311]; wound healing [GO:0042060] GO:0001540; GO:0001666; GO:0001889; GO:0001965; GO:0001993; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0002086; GO:0003059; GO:0004930; GO:0004941; GO:0005634; GO:0005737; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0005901; GO:0006366; GO:0006898; GO:0006939; GO:0007186; GO:0007189; GO:0007190; GO:0007565; GO:0007568; GO:0008179; GO:0008284; GO:0008306; GO:0009409; GO:0010739; GO:0010765; GO:0015459; GO:0016020; GO:0016324; GO:0016525; GO:0019899; GO:0030165; GO:0030279; GO:0030424; GO:0030425; GO:0030501; GO:0031649; GO:0031713; GO:0032570; GO:0032781; GO:0032809; GO:0033574; GO:0035249; GO:0035255; GO:0035811; GO:0040015; GO:0042060; GO:0042311; GO:0042383; GO:0042802; GO:0042803; GO:0043065; GO:0043197; GO:0043231; GO:0043235; GO:0043268; GO:0043410; GO:0043627; GO:0044849; GO:0044877; GO:0045211; GO:0045453; GO:0045823; GO:0045944; GO:0045986; GO:0048633; GO:0050728; GO:0050873; GO:0051379; GO:0051380; GO:0051721; GO:0051924; GO:0051930; GO:0060079; GO:0061885; GO:0071456; GO:0071548; GO:0071867; GO:0071869; GO:0071875; GO:0071880; GO:0071902; GO:0090331; GO:0090722; GO:0097421; GO:0098685; GO:0098793; GO:0098978; GO:0098992; GO:0099171; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:1905665; GO:2000969 23806 FUN_035500 2671 1414 581 1992 1399 ptg000025l:8222436-8226960 Q5R2J4 1.62e-68 Protein APCDD1 (Adenomatosis polyposis coli down-regulated 1 protein homolog) (PsAPCDD1) Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis) negative regulation of Wnt signaling pathway [GO:0030178]; Wnt signaling pathway [GO:0016055] GO:0005615; GO:0005886; GO:0016055; GO:0017147; GO:0030178 23807 FUN_042614 425 274 336 534 521 NA NA NA NA NA NA NA 23808 FUN_041585 11915 36304 8401 12576 14641 ptg000035l:5511489-5512352 P18320 1.09e-40 Profilin Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) regulation of cellular component biogenesis [GO:0044087] GO:0003779; GO:0005737; GO:0005856; GO:0044087 23809 FUN_041585 11915 36304 8401 12576 14641 ptg000035l:5511489-5512352 P18320 1.84e-21 Profilin Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) regulation of cellular component biogenesis [GO:0044087] GO:0003779; GO:0005737; GO:0005856; GO:0044087 23810 FUN_020851 9317 12403 6959 9111 3676 NA NA NA NA NA NA NA 23811 FUN_020850 1841 1185 1085 1970 1450 NA NA NA NA NA NA NA 23812 FUN_020853 888 1396 552 931 668 ptg000015l:9257138-9261814 Q3MII6 4.15e-74 TBC1 domain family member 25 Homo sapiens (Human) activation of GTPase activity [GO:0090630]; autophagy [GO:0006914]; regulation of autophagosome maturation [GO:1901096] GO:0005096; GO:0005776; GO:0006914; GO:0031410; GO:0090630; GO:1901096 23813 FUN_020852 8819 8638 4503 6393 6039 NA NA NA NA NA NA NA 23814 FUN_020855 329 96 77 132 52 NA NA NA NA NA NA NA 23815 FUN_020854 0 0 0 14 2 NA NA NA NA NA NA NA 23816 FUN_020857 51 21 5 32 61 NA NA NA NA NA NA NA 23817 FUN_020856 0 0 19 0 0 NA NA NA NA NA NA NA 23818 FUN_020859 0 0 35 0 118 NA NA NA NA NA NA NA 23819 FUN_022981 3190 3062 1765 2596 2193 ptg000017l:2216302-2222033 Q6GLT8 1.21e-22 Fumarylacetoacetate hydrolase domain-containing protein 2 (EC 3.-.-.-) Xenopus laevis (African clawed frog) NA GO:0016787; GO:0046872 23820 FUN_022981 3190 3062 1765 2596 2193 ptg000017l:2216302-2222033 Q6GLT8 5.82e-21 Fumarylacetoacetate hydrolase domain-containing protein 2 (EC 3.-.-.-) Xenopus laevis (African clawed frog) NA GO:0016787; GO:0046872 23821 FUN_022980 660 623 287 597 499 ptg000017l:2209304-2212603 O00567 5.52e-45 Nucleolar protein 56 (Nucleolar protein 5A) Homo sapiens (Human) rRNA processing [GO:0006364] GO:0001650; GO:0003723; GO:0005654; GO:0005730; GO:0005732; GO:0005737; GO:0006364; GO:0016020; GO:0030515; GO:0031428; GO:0032040; GO:0045296; GO:0070761; GO:1990226 23822 FUN_022983 0 0 34 34 0 NA NA NA NA NA NA NA 23823 FUN_022985 39 42 36 56 42 NA NA NA NA NA NA NA 23824 FUN_022984 113 21 16 56 35 NA NA NA NA NA NA NA 23825 FUN_022987 17 0 17 45 90 NA NA NA NA NA NA NA 23826 FUN_022986 48 2 426 334 78 NA NA NA NA NA NA NA 23827 FUN_022989 374 375 245 303 458 ptg000017l:2295471-2298076 Q8AVJ1 1.85e-30 Proline-rich protein 5 (Protein observed with Rictor-1) (Protor-1) Xenopus laevis (African clawed frog) NA NA 23828 FUN_022988 4197 3211 2140 3147 2082 NA NA NA NA NA NA NA 23829 FUN_012159 2725 7155 5131 2400 3911 NA NA NA NA NA NA NA 23830 FUN_012158 0 0 0 6 32 NA NA NA NA NA NA NA 23831 FUN_017308 0 0 0 0 8 NA NA NA NA NA NA NA 23832 FUN_017306 5 0 2 1 54 NA NA NA NA NA NA NA 23833 FUN_012152 2302 1304 1323 1120 1459 NA NA NA NA NA NA NA 23834 FUN_012155 2483 2047 1233 1580 1866 NA NA NA NA NA NA NA 23835 FUN_012154 892 1026 363 637 527 NA NA NA NA NA NA NA 23836 FUN_017301 21 0 7 56 0 NA NA NA NA NA NA NA 23837 FUN_012146 386 313 165 324 356 NA NA NA NA NA NA NA 23838 FUN_010161 234 26 9 49 10 NA NA NA NA NA NA NA 23839 FUN_017963 68 73 54 0 75 NA NA NA NA NA NA NA 23840 FUN_038865 11 5 29 0 176 NA NA NA NA NA NA NA 23841 FUN_038864 0 0 0 0 10 NA NA NA NA NA NA NA 23842 FUN_038867 0 0 0 8 0 NA NA NA NA NA NA NA 23843 FUN_038869 90 0 0 18 28 NA NA NA NA NA NA NA 23844 FUN_038868 0 0 0 0 17 NA NA NA NA NA NA NA 23845 FUN_017961 0 0 0 0 18 NA NA NA NA NA NA NA 23846 FUN_017960 23 0 0 14 0 NA NA NA NA NA NA NA 23847 FUN_018715 0 0 0 62 0 NA NA NA NA NA NA NA 23848 FUN_017966 708 671 578 945 954 NA NA NA NA NA NA NA 23849 FUN_027858 12 0 0 15 17 NA NA NA NA NA NA NA 23850 FUN_027859 48 15 63 48 0 NA NA NA NA NA NA NA 23851 FUN_017965 145 51 44 80 265 NA NA NA NA NA NA NA 23852 FUN_027850 10804 5570 7807 14319 12529 NA NA NA NA NA NA NA 23853 FUN_027851 91 23 164 134 161 NA NA NA NA NA NA NA 23854 FUN_027852 1570 1086 1290 1402 744 NA NA NA NA NA NA NA 23855 FUN_018716 0 0 0 69 0 NA NA NA NA NA NA NA 23856 FUN_027855 48 7 6 18 36 NA NA NA NA NA NA NA 23857 FUN_027856 0 0 0 0 15 NA NA NA NA NA NA NA 23858 FUN_014658 236 141 116 130 116 NA NA NA NA NA NA NA 23859 FUN_014659 291 420 130 263 520 NA NA NA NA NA NA NA 23860 FUN_023358 111 81 77 146 105 NA NA NA NA NA NA NA 23861 FUN_014654 155 95 49 186 316 NA NA NA NA NA NA NA 23862 FUN_023356 74 10 118 26 192 NA NA NA NA NA NA NA 23863 FUN_023355 2 34 2 24 32 NA NA NA NA NA NA NA 23864 FUN_023354 13 14 0 27 11 NA NA NA NA NA NA NA 23865 FUN_026181 1556 1543 1014 1506 2051 NA NA NA NA NA NA NA 23866 FUN_026180 186 154 139 396 264 NA NA NA NA NA NA NA 23867 FUN_014652 2217 2566 1452 1875 1867 NA NA NA NA NA NA NA 23868 FUN_014653 530 263 399 741 538 NA NA NA NA NA NA NA 23869 FUN_036529 1659 842 1140 1769 131 ptg000025l:19355104-19381077 P14381 1.01e-72 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 23870 FUN_025988 1538 1372 472 1169 873 ptg000020l:2897996-2915556 P27041 7.09e-59 Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468] GO:0004675; GO:0005524; GO:0006468; GO:0016020 23871 FUN_025989 21 0 0 8 14 NA NA NA NA NA NA NA 23872 FUN_025980 3734 4220 1744 4677 6285 ptg000020l:2766716-2770202 P54965 3.39e-21 Conjugated bile acid hydrolase (CBAH) (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (CBAH-1) (Choloylglycine hydrolase) (EC 3.5.1.24) Clostridium perfringens (strain 13 / Type A) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 23873 FUN_009550 93 99 73 61 135 ptg000004l:8421540-8431784 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23874 FUN_009550 93 99 73 61 135 ptg000004l:8421540-8431784 Q96AY4 2.01e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23875 FUN_009550 93 99 73 61 135 ptg000004l:8421540-8431784 Q96AY4 1.35e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23876 FUN_009550 93 99 73 61 135 ptg000004l:8421540-8431784 Q96AY4 2.78e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23877 FUN_009550 93 99 73 61 135 ptg000004l:8421540-8431784 Q96AY4 1.56e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23878 FUN_025982 0 0 225 0 50 NA NA NA NA NA NA NA 23879 FUN_009555 0 0 12 14 0 NA NA NA NA NA NA NA 23880 FUN_025985 928 1063 394 382 346 NA NA NA NA NA NA NA 23881 FUN_025986 2890 2491 1597 2148 1838 NA NA NA NA NA NA NA 23882 FUN_025987 1597 1050 924 1584 862 ptg000020l:2884869-2892912 P49183 2.45e-25 Deoxyribonuclease-1 (EC 3.1.21.1) (Deoxyribonuclease I) (DNase I) Mus musculus (Mouse) apoptotic process [GO:0006915]; DNA catabolic process [GO:0006308]; DNA catabolic process, endonucleolytic [GO:0000737]; neutrophil activation involved in immune response [GO:0002283]; regulation of acute inflammatory response [GO:0002673]; regulation of neutrophil mediated cytotoxicity [GO:0070948] GO:0000737; GO:0002283; GO:0002673; GO:0003677; GO:0003779; GO:0004530; GO:0004536; GO:0005576; GO:0005634; GO:0005635; GO:0006308; GO:0006915; GO:0042588; GO:0070948 23883 FUN_039688 10 35 54 57 0 NA NA NA NA NA NA NA 23884 FUN_026729 565 958 185 339 288 NA NA NA NA NA NA NA 23885 FUN_026728 146 156 112 147 113 NA NA NA NA NA NA NA 23886 FUN_019309 6 0 21 0 67 NA NA NA NA NA NA NA 23887 FUN_019308 0 0 0 14 0 NA NA NA NA NA NA NA 23888 FUN_026721 165 104 71 143 89 NA NA NA NA NA NA NA 23889 FUN_026720 14 0 0 23 1 NA NA NA NA NA NA NA 23890 FUN_019300 0 0 0 0 10 NA NA NA NA NA NA NA 23891 FUN_026726 50 51 3 69 77 NA NA NA NA NA NA NA 23892 FUN_039808 5085 3343 1770 5055 4887 ptg000031l:322755-330157 P42026 6.67e-29 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 7.1.1.2) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit) (PSST subunit) Bos taurus (Bovine) aerobic respiration [GO:0009060]; electron transport coupled proton transport [GO:0015990]; mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981] GO:0005743; GO:0005747; GO:0006120; GO:0008137; GO:0009060; GO:0015990; GO:0032981; GO:0046872; GO:0048038; GO:0051539 23893 FUN_039809 15 32 9 47 82 NA NA NA NA NA NA NA 23894 FUN_038297 35663 27844 20791 41889 25025 ptg000027l:5382873-5411817 P35749 3.07e-52 Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cardiac muscle cell development [GO:0055013]; elastic fiber assembly [GO:0048251]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939] GO:0000146; GO:0005516; GO:0005524; GO:0005829; GO:0005859; GO:0006939; GO:0008307; GO:0016460; GO:0030241; GO:0031032; GO:0032982; GO:0042470; GO:0048251; GO:0051015; GO:0055013; GO:0070062 23895 FUN_038297 35663 27844 20791 41889 25025 ptg000027l:5382873-5411817 P35749 9.48e-37 Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cardiac muscle cell development [GO:0055013]; elastic fiber assembly [GO:0048251]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939] GO:0000146; GO:0005516; GO:0005524; GO:0005829; GO:0005859; GO:0006939; GO:0008307; GO:0016460; GO:0030241; GO:0031032; GO:0032982; GO:0042470; GO:0048251; GO:0051015; GO:0055013; GO:0070062 23896 FUN_038297 35663 27844 20791 41889 25025 ptg000027l:5382873-5411817 P35749 1.6e-32 Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cardiac muscle cell development [GO:0055013]; elastic fiber assembly [GO:0048251]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939] GO:0000146; GO:0005516; GO:0005524; GO:0005829; GO:0005859; GO:0006939; GO:0008307; GO:0016460; GO:0030241; GO:0031032; GO:0032982; GO:0042470; GO:0048251; GO:0051015; GO:0055013; GO:0070062 23897 FUN_038297 35663 27844 20791 41889 25025 ptg000027l:5382873-5411817 P35749 9.67e-22 Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC) Homo sapiens (Human) actomyosin structure organization [GO:0031032]; cardiac muscle cell development [GO:0055013]; elastic fiber assembly [GO:0048251]; skeletal muscle myosin thick filament assembly [GO:0030241]; smooth muscle contraction [GO:0006939] GO:0000146; GO:0005516; GO:0005524; GO:0005829; GO:0005859; GO:0006939; GO:0008307; GO:0016460; GO:0030241; GO:0031032; GO:0032982; GO:0042470; GO:0048251; GO:0051015; GO:0055013; GO:0070062 23898 FUN_039800 2685 1775 1318 2160 1451 NA NA NA NA NA NA NA 23899 FUN_039801 0 0 0 7 3 NA NA NA NA NA NA NA 23900 FUN_039802 28 31 6 21 3 NA NA NA NA NA NA NA 23901 FUN_039803 145 381 119 516 568 NA NA NA NA NA NA NA 23902 FUN_039804 93 78 13 234 69 NA NA NA NA NA NA NA 23903 FUN_039805 17 0 46 17 128 ptg000031l:305802-307694 Q7SC45 4.33e-24 Protein btn-1 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) L-arginine transmembrane transport [GO:1903826]; lysine transport [GO:0015819]; regulation of intracellular pH [GO:0051453] GO:0000324; GO:0005773; GO:0005774; GO:0015819; GO:0051453; GO:1903826 23904 FUN_039806 0 18 0 0 0 NA NA NA NA NA NA NA 23905 FUN_039807 0 0 0 0 93 NA NA NA NA NA NA NA 23906 FUN_022408 2398 1633 1187 2219 2128 NA NA NA NA NA NA NA 23907 FUN_022409 345 240 147 286 103 NA NA NA NA NA NA NA 23908 FUN_022404 567 736 134 620 190 NA NA NA NA NA NA NA 23909 FUN_022405 111 160 56 160 88 NA NA NA NA NA NA NA 23910 FUN_022406 3414 2304 1682 3111 2783 NA NA NA NA NA NA NA 23911 FUN_022407 39 86 46 63 69 NA NA NA NA NA NA NA 23912 FUN_022400 45 69 29 58 24 NA NA NA NA NA NA NA 23913 FUN_022401 201 179 61 190 78 NA NA NA NA NA NA NA 23914 FUN_022402 0 61 45 32 19 NA NA NA NA NA NA NA 23915 FUN_022403 785 470 465 987 656 NA NA NA NA NA NA NA 23916 FUN_024762 2984 2703 1771 1020 1292 ptg000018l:10717373-10721430 Q5U3V7 3.24e-25 Solute carrier family 25 member 43 Danio rerio (Zebrafish) (Brachydanio rerio) transmembrane transport [GO:0055085] GO:0005743; GO:0055085 23917 FUN_024761 4475 4842 2123 5043 3904 ptg000018l:10713406-10716203 Q9Z255 3.83e-23 Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone ubiquitination [GO:0016574]; in utero embryonic development [GO:0001701]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of cell population proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to UV [GO:0009411] GO:0000209; GO:0000785; GO:0001701; GO:0001741; GO:0001835; GO:0004842; GO:0005524; GO:0006281; GO:0008284; GO:0009411; GO:0016567; GO:0016574; GO:0031625; GO:0033503; GO:0033522; GO:0043161; GO:0051865; GO:0060135; GO:0061631; GO:0070936; GO:0070979 23918 FUN_024761 4475 4842 2123 5043 3904 ptg000018l:10713406-10716203 Q9Z255 3.83e-23 Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (mHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) Mus musculus (Mouse) blastocyst hatching [GO:0001835]; DNA repair [GO:0006281]; histone H2A ubiquitination [GO:0033522]; histone ubiquitination [GO:0016574]; in utero embryonic development [GO:0001701]; maternal process involved in female pregnancy [GO:0060135]; positive regulation of cell population proliferation [GO:0008284]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; response to UV [GO:0009411] GO:0000209; GO:0000785; GO:0001701; GO:0001741; GO:0001835; GO:0004842; GO:0005524; GO:0006281; GO:0008284; GO:0009411; GO:0016567; GO:0016574; GO:0031625; GO:0033503; GO:0033522; GO:0043161; GO:0051865; GO:0060135; GO:0061631; GO:0070936; GO:0070979 23919 FUN_024760 127 32 26 37 19 NA NA NA NA NA NA NA 23920 FUN_024765 2168 1542 1035 1738 1093 NA NA NA NA NA NA NA 23921 FUN_024764 1044 638 393 1011 600 NA NA NA NA NA NA NA 23922 FUN_024769 847 208 210 412 191 ptg000018l:10778222-10839694 Q99315 8.4e-57 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 23923 FUN_024769 847 208 210 412 191 ptg000018l:10778222-10839694 Q99315 8.4e-57 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 23924 FUN_024768 3 0 5 0 43 NA NA NA NA NA NA NA 23925 FUN_008141 0 4 433 359 9 NA NA NA NA NA NA NA 23926 FUN_041755 0 0 0 0 6 NA NA NA NA NA NA NA 23927 FUN_040236 1810 1813 1813 1958 1013 NA NA NA NA NA NA NA 23928 FUN_002811 429 145 172 164 114 ntLink_8:6503974-6509588 Q6DDT4 3.37e-68 NA NA NA NA 23929 FUN_002811 429 145 172 164 114 ntLink_8:6503974-6509588 Q6DDT4 7.02e-27 NA NA NA NA 23930 FUN_017688 0 2 0 0 72 NA NA NA NA NA NA NA 23931 FUN_017689 0 0 0 0 188 NA NA NA NA NA NA NA 23932 FUN_017682 15 38 0 9 0 NA NA NA NA NA NA NA 23933 FUN_017680 0 0 0 0 76 NA NA NA NA NA NA NA 23934 FUN_025984 65269 36172 28079 123625 106517 ptg000020l:2794632-2859859 B8V7R6 2.22e-39 Collagen alpha chain Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005201; GO:0005576; GO:0005581 23935 FUN_017686 0 6 17 9 41 NA NA NA NA NA NA NA 23936 FUN_017685 0 0 0 0 28 NA NA NA NA NA NA NA 23937 FUN_002812 458 352 444 406 417 NA NA NA NA NA NA NA 23938 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 1.37e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23939 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 6.49e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23940 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 1.81e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23941 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 4.38e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23942 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 7.58e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23943 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 1.93e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23944 FUN_002815 0 0 0 0 7 ntLink_8:6554419-6559468 Q96AY4 6.41e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 23945 FUN_009842 1366 1014 775 1556 533 ptg000004l:12457489-12468751 Q9JIF3 4.31e-48 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Mus musculus (Mouse) dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; galactose transmembrane transport [GO:0015757]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; insulin receptor signaling pathway [GO:0008286]; male meiosis I [GO:0007141]; response to hypoxia [GO:0001666]; transmembrane transport [GO:0055085] GO:0001666; GO:0005353; GO:0005354; GO:0005355; GO:0005536; GO:0005886; GO:0006006; GO:0007141; GO:0008021; GO:0008286; GO:0015284; GO:0015755; GO:0015757; GO:0016020; GO:0022857; GO:0030659; GO:0033300; GO:0055085; GO:0070837; GO:1904659 23946 FUN_036044 3685 2176 1505 2750 2766 ptg000025l:14813408-14822896 Q86WU2 1.58e-21 Probable D-lactate dehydrogenase, mitochondrial (DLD) (Lactate dehydrogenase D) (EC 1.1.2.4) Homo sapiens (Human) lactate catabolic process [GO:1903457] GO:0004458; GO:0005739; GO:0005743; GO:0008720; GO:0050660; GO:0071949; GO:1903457 23947 FUN_008142 28 0 0 0 0 NA NA NA NA NA NA NA 23948 FUN_035242 328 111 90 197 275 ptg000025l:5523396-5529403 Q96AN5 7.07e-37 Transmembrane protein 143 Homo sapiens (Human) NA GO:0005739; GO:0016020 23949 FUN_035243 2974 1738 1208 2403 2254 NA NA NA NA NA NA NA 23950 FUN_035240 12559 10207 2499 3258 5528 ptg000025l:5512007-5516847 Q9CYL5 6.16e-28 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Mus musculus (Mouse) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070374 23951 FUN_035241 1298 1004 796 655 438 ptg000025l:5520412-5522047 Q5RD73 1.39e-36 Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Vaccinia H1-related phosphatase) (VHR) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) dephosphorylation [GO:0016311]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005634; GO:0006470; GO:0008138; GO:0016311; GO:0016791; GO:0017018 23952 FUN_035247 6409 6373 4323 8848 5415 NA NA NA NA NA NA NA 23953 FUN_035244 1728 1338 518 904 832 NA NA NA NA NA NA NA 23954 FUN_035245 65 102 60 63 61 NA NA NA NA NA NA NA 23955 FUN_006396 0 0 0 2 9 NA NA NA NA NA NA NA 23956 FUN_006392 0 0 0 0 89 NA NA NA NA NA NA NA 23957 FUN_006391 0 0 16 28 123 NA NA NA NA NA NA NA 23958 FUN_038043 7069 4536 1871 8360 8537 ptg000027l:1737129-1767945 Q8N122 2.72e-25 Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of autophagy [GO:0010506]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001938; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006974; GO:0008361; GO:0009267; GO:0009410; GO:0010494; GO:0010506; GO:0010507; GO:0010800; GO:0016310; GO:0019901; GO:0030291; GO:0030295; GO:0030307; GO:0030425; GO:0030674; GO:0031669; GO:0031929; GO:0031931; GO:0032008; GO:0033138; GO:0035176; GO:0038202; GO:0043025; GO:0044877; GO:0045821; GO:0045945; GO:0046889; GO:0071230; GO:0071233; GO:0071456; GO:0071470; GO:0071889; GO:0071902; GO:1900087; GO:1905857 23959 FUN_038043 7069 4536 1871 8360 8537 ptg000027l:1737129-1767945 Q8N122 7.92e-25 Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of autophagy [GO:0010506]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001938; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006974; GO:0008361; GO:0009267; GO:0009410; GO:0010494; GO:0010506; GO:0010507; GO:0010800; GO:0016310; GO:0019901; GO:0030291; GO:0030295; GO:0030307; GO:0030425; GO:0030674; GO:0031669; GO:0031929; GO:0031931; GO:0032008; GO:0033138; GO:0035176; GO:0038202; GO:0043025; GO:0044877; GO:0045821; GO:0045945; GO:0046889; GO:0071230; GO:0071233; GO:0071456; GO:0071470; GO:0071889; GO:0071902; GO:1900087; GO:1905857 23960 FUN_038043 7069 4536 1871 8360 8537 ptg000027l:1737129-1767945 Q8N122 9.77e-24 Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of autophagy [GO:0010506]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001938; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006974; GO:0008361; GO:0009267; GO:0009410; GO:0010494; GO:0010506; GO:0010507; GO:0010800; GO:0016310; GO:0019901; GO:0030291; GO:0030295; GO:0030307; GO:0030425; GO:0030674; GO:0031669; GO:0031929; GO:0031931; GO:0032008; GO:0033138; GO:0035176; GO:0038202; GO:0043025; GO:0044877; GO:0045821; GO:0045945; GO:0046889; GO:0071230; GO:0071233; GO:0071456; GO:0071470; GO:0071889; GO:0071902; GO:1900087; GO:1905857 23961 FUN_038043 7069 4536 1871 8360 8537 ptg000027l:1737129-1767945 Q8N122 9.77e-24 Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hypoxia [GO:0071456]; cellular response to leucine [GO:0071233]; cellular response to nutrient levels [GO:0031669]; cellular response to osmotic stress [GO:0071470]; cellular response to starvation [GO:0009267]; negative regulation of autophagy [GO:0010507]; phosphorylation [GO:0016310]; positive regulation of cell growth [GO:0030307]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glycolytic process [GO:0045821]; positive regulation of lipid biosynthetic process [GO:0046889]; positive regulation of pentose-phosphate shunt [GO:1905857]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of TOR signaling [GO:0032008]; positive regulation of transcription by RNA polymerase III [GO:0045945]; regulation of autophagy [GO:0010506]; regulation of cell growth [GO:0001558]; regulation of cell size [GO:0008361]; response to xenobiotic stimulus [GO:0009410]; social behavior [GO:0035176]; TOR signaling [GO:0031929]; TORC1 signaling [GO:0038202] GO:0001002; GO:0001003; GO:0001006; GO:0001156; GO:0001558; GO:0001938; GO:0005654; GO:0005737; GO:0005764; GO:0005765; GO:0005829; GO:0006974; GO:0008361; GO:0009267; GO:0009410; GO:0010494; GO:0010506; GO:0010507; GO:0010800; GO:0016310; GO:0019901; GO:0030291; GO:0030295; GO:0030307; GO:0030425; GO:0030674; GO:0031669; GO:0031929; GO:0031931; GO:0032008; GO:0033138; GO:0035176; GO:0038202; GO:0043025; GO:0044877; GO:0045821; GO:0045945; GO:0046889; GO:0071230; GO:0071233; GO:0071456; GO:0071470; GO:0071889; GO:0071902; GO:1900087; GO:1905857 23962 FUN_038042 1386 692 663 922 634 NA NA NA NA NA NA NA 23963 FUN_038041 550 531 167 581 262 ptg000027l:1716540-1726807 Q15022 6.84e-39 Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog) Homo sapiens (Human) cell population proliferation [GO:0008283]; dosage compensation by inactivation of X chromosome [GO:0009048]; facultative heterochromatin formation [GO:0140718]; histone methylation [GO:0016571]; histone ubiquitination [GO:0016574]; negative regulation of cell differentiation [GO:0045596]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284] GO:0000122; GO:0000978; GO:0001222; GO:0001739; GO:0005634; GO:0005654; GO:0005677; GO:0005730; GO:0008047; GO:0008283; GO:0008284; GO:0009048; GO:0016571; GO:0016574; GO:0016604; GO:0031490; GO:0032993; GO:0035064; GO:0035098; GO:0042054; GO:0045596; GO:0046872; GO:0048709; GO:0106222; GO:0140718; GO:1990841; GO:1990904 23964 FUN_038041 550 531 167 581 262 ptg000027l:1716540-1726807 Q15022 6.84e-39 Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog) Homo sapiens (Human) cell population proliferation [GO:0008283]; dosage compensation by inactivation of X chromosome [GO:0009048]; facultative heterochromatin formation [GO:0140718]; histone methylation [GO:0016571]; histone ubiquitination [GO:0016574]; negative regulation of cell differentiation [GO:0045596]; negative regulation of transcription by RNA polymerase II [GO:0000122]; oligodendrocyte differentiation [GO:0048709]; positive regulation of cell population proliferation [GO:0008284] GO:0000122; GO:0000978; GO:0001222; GO:0001739; GO:0005634; GO:0005654; GO:0005677; GO:0005730; GO:0008047; GO:0008283; GO:0008284; GO:0009048; GO:0016571; GO:0016574; GO:0016604; GO:0031490; GO:0032993; GO:0035064; GO:0035098; GO:0042054; GO:0045596; GO:0046872; GO:0048709; GO:0106222; GO:0140718; GO:1990841; GO:1990904 23965 FUN_038040 859 487 410 927 675 NA NA NA NA NA NA NA 23966 FUN_038047 240 130 386 351 242 NA NA NA NA NA NA NA 23967 FUN_038046 0 0 0 15 0 NA NA NA NA NA NA NA 23968 FUN_038045 0 56 27 81 73 NA NA NA NA NA NA NA 23969 FUN_038049 500 833 508 710 440 NA NA NA NA NA NA NA 23970 FUN_038048 149 122 200 364 236 NA NA NA NA NA NA NA 23971 FUN_027900 294 540 268 234 174 NA NA NA NA NA NA NA 23972 FUN_036917 362 302 344 248 274 NA NA NA NA NA NA NA 23973 FUN_036916 410 276 177 503 408 NA NA NA NA NA NA NA 23974 FUN_036915 5106 4292 2119 3195 2202 ptg000026l:3360665-3375067 Q6ZQY2 8.42e-24 Leucine-rich repeat-containing protein 74B Homo sapiens (Human) NA NA 23975 FUN_036914 0 7 16 0 20 ptg000026l:3355657-3358173 Q6ZQY2 2.08e-27 Leucine-rich repeat-containing protein 74B Homo sapiens (Human) NA NA 23976 FUN_036913 1116 664 302 570 534 NA NA NA NA NA NA NA 23977 FUN_036912 2661 1839 1648 2388 1575 NA NA NA NA NA NA NA 23978 FUN_036911 0 0 17 20 40 NA NA NA NA NA NA NA 23979 FUN_028227 339 774 159 405 621 NA NA NA NA NA NA NA 23980 FUN_036919 3324 2735 1466 2488 2699 ptg000026l:3391264-3396308 P13437 2.99e-31 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) Rattus norvegicus (Rat) acetyl-CoA metabolic process [GO:0006084]; cellular response to hypoxia [GO:0071456]; fatty acid beta-oxidation [GO:0006635]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029] GO:0003985; GO:0003986; GO:0003988; GO:0005739; GO:0005759; GO:0006084; GO:0006635; GO:0016290; GO:0047617; GO:0071456; GO:0102991; GO:1901029; GO:1902109 23981 FUN_036919 3324 2735 1466 2488 2699 ptg000026l:3391264-3396308 P13437 9.52e-23 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-, EC 3.1.2.1, EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) Rattus norvegicus (Rat) acetyl-CoA metabolic process [GO:0006084]; cellular response to hypoxia [GO:0071456]; fatty acid beta-oxidation [GO:0006635]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901029] GO:0003985; GO:0003986; GO:0003988; GO:0005739; GO:0005759; GO:0006084; GO:0006635; GO:0016290; GO:0047617; GO:0071456; GO:0102991; GO:1901029; GO:1902109 23982 FUN_027907 792 398 254 323 0 NA NA NA NA NA NA NA 23983 FUN_024576 1109 618 429 863 249 ptg000018l:8519872-8524478 O95671 1.46e-22 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 23984 FUN_027905 3 55 7 0 185 NA NA NA NA NA NA NA 23985 FUN_035796 6 0 0 0 0 NA NA NA NA NA NA NA 23986 FUN_035790 0 0 0 0 37 NA NA NA NA NA NA NA 23987 FUN_035791 0 0 0 0 8 NA NA NA NA NA NA NA 23988 FUN_004897 15877 18009 5857 16501 11412 NA NA NA NA NA NA NA 23989 FUN_004896 1913 1327 641 2037 1017 ntLink_8:28478313-28487473 Q641Z2 1.78e-32 Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) Rattus norvegicus (Rat) negative regulation of neuron projection development [GO:0010977]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein dephosphorylation [GO:0006470] GO:0004725; GO:0005737; GO:0006470; GO:0010977; GO:0035335; GO:0044306; GO:1903078 23990 FUN_004895 11578 7878 5948 9415 7135 ntLink_8:28467948-28471241 Q61532 5.03e-68 Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) Mus musculus (Mouse) cell cycle [GO:0007049]; intracellular signal transduction [GO:0035556]; positive regulation of dendritic spine development [GO:0060999]; protein phosphorylation [GO:0006468] GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0006468; GO:0007049; GO:0019901; GO:0032156; GO:0032991; GO:0035556; GO:0046982; GO:0060999; GO:0106310 23991 FUN_031498 0 0 9 17 67 NA NA NA NA NA NA NA 23992 FUN_004893 3255 2846 1970 2317 1218 NA NA NA NA NA NA NA 23993 FUN_004892 805 443 390 655 270 ntLink_8:28439210-28440131 P59889 2.13e-48 Zinc transporter ZIP1 (DrZIP1) (Solute carrier family 39 member 1) (Zrt- and Irt-like protein 1) (ZIP-1) Danio rerio (Zebrafish) (Brachydanio rerio) zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0005385; GO:0005886; GO:0006829; GO:0008270; GO:0016020; GO:0071577 23994 FUN_004891 103045 124653 86258 81148 46247 NA NA NA NA NA NA NA 23995 FUN_004890 348 367 376 407 182 NA NA NA NA NA NA NA 23996 FUN_031493 1671 1238 538 1066 2146 ptg000023l:22000277-22009335 Q5M7F6 5.1e-26 Dynein axonemal assembly factor 10 (WD repeat-containing protein 92) Xenopus laevis (African clawed frog) apoptotic process [GO:0006915]; axonemal dynein complex assembly [GO:0070286] GO:0006915; GO:0070286; GO:0120293 23997 FUN_031492 151 184 63 136 215 NA NA NA NA NA NA NA 23998 FUN_031491 232 207 59 203 203 NA NA NA NA NA NA NA 23999 FUN_031490 1307 672 452 1065 324 NA NA NA NA NA NA NA 24000 FUN_031497 7173 5060 3237 7815 6505 NA NA NA NA NA NA NA 24001 FUN_031496 36 10 0 45 66 NA NA NA NA NA NA NA 24002 FUN_004899 2833 3603 1910 3836 4031 NA NA NA NA NA NA NA 24003 FUN_004898 1899 992 1050 1009 666 ntLink_8:28492341-28494837 O95394 2.64e-155 Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] GO:0000287; GO:0004610; GO:0005829; GO:0005975; GO:0006041; GO:0006048; GO:0006487; GO:0006493; GO:0007283; GO:0030097 24004 FUN_004898 1899 992 1050 1009 666 ntLink_8:28492341-28494837 O95394 2.18e-32 Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; glucosamine metabolic process [GO:0006041]; hemopoiesis [GO:0030097]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; spermatogenesis [GO:0007283]; UDP-N-acetylglucosamine biosynthetic process [GO:0006048] GO:0000287; GO:0004610; GO:0005829; GO:0005975; GO:0006041; GO:0006048; GO:0006487; GO:0006493; GO:0007283; GO:0030097 24005 FUN_038128 566 379 274 502 457 ptg000027l:2842738-2847032 Q5M9H0 1.04e-31 Ankyrin repeat and SAM domain-containing protein 3 Rattus norvegicus (Rat) NA GO:0005737; GO:0005929 24006 FUN_030736 16 22 0 3 0 NA NA NA NA NA NA NA 24007 FUN_001629 38 53 14 84 27 NA NA NA NA NA NA NA 24008 FUN_001628 113950 118869 43321 86453 58830 ntLink_6:14446230-14448158 P53782 7.2e-51 G1/S-specific cyclin-D2 Xenopus laevis (African clawed frog) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0005737; GO:0016538; GO:0031965; GO:0044772; GO:0051301 24009 FUN_001627 0 14 5 5 7 NA NA NA NA NA NA NA 24010 FUN_001626 292 224 101 294 199 NA NA NA NA NA NA NA 24011 FUN_001625 0 0 7 0 9 NA NA NA NA NA NA NA 24012 FUN_001624 1984 895 989 2191 1556 NA NA NA NA NA NA NA 24013 FUN_001623 60 113 44 101 79 NA NA NA NA NA NA NA 24014 FUN_001622 353 270 269 509 441 NA NA NA NA NA NA NA 24015 FUN_001621 4036 3062 2062 4302 2784 NA NA NA NA NA NA NA 24016 FUN_001620 99 50 57 117 162 NA NA NA NA NA NA NA 24017 FUN_007276 2 0 8 0 15 NA NA NA NA NA NA NA 24018 FUN_007274 8 0 3 4 22 NA NA NA NA NA NA NA 24019 FUN_007275 30 0 39 1 40 ptg000002l:859528-859840 Q6LAF1 8.65e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24020 FUN_029942 0 0 0 19 0 NA NA NA NA NA NA NA 24021 FUN_038121 80 21 14 75 96 NA NA NA NA NA NA NA 24022 FUN_029944 0 0 0 43 0 NA NA NA NA NA NA NA 24023 FUN_032223 186 37 67 87 143 ptg000023l:29873739-29874807 Q969F8 9.96e-27 KiSS-1 receptor (KiSS-1R) (G-protein coupled receptor 54) (G-protein coupled receptor OT7T175) (hOT7T175) (Hypogonadotropin-1) (Kisspeptins receptor) (Metastin receptor) Homo sapiens (Human) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0005886; GO:0005929; GO:0007186; GO:0007218; GO:0008188; GO:0008528; GO:0009986; GO:0016020; GO:0043231 24024 FUN_023121 421 285 245 314 235 NA NA NA NA NA NA NA 24025 FUN_038124 2505 749 1807 2388 2819 ptg000027l:2822390-2824587 Q964E3 5.21e-178 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 24026 FUN_038124 2505 749 1807 2388 2819 ptg000027l:2822390-2824587 Q964E3 8.83e-58 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 24027 FUN_038124 2505 749 1807 2388 2819 ptg000027l:2822390-2824587 Q964E3 8.83e-58 Actin, cytoplasmic (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic, intermediate form] Biomphalaria alexandrina (Bloodfluke planorb) (Freshwater snail) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 24028 FUN_044200 37 80 56 49 150 NA NA NA NA NA NA NA 24029 FUN_038125 403 166 143 76 91 NA NA NA NA NA NA NA 24030 FUN_036265 38 0 8 8 106 NA NA NA NA NA NA NA 24031 FUN_036264 3090 2324 1841 3003 2602 NA NA NA NA NA NA NA 24032 FUN_023123 6 40 4 12 12 NA NA NA NA NA NA NA 24033 FUN_036261 52 0 39 13 260 NA NA NA NA NA NA NA 24034 FUN_036260 4882 4572 2459 5844 5243 ptg000025l:17251285-17257273 Q9BR39 6.69e-47 Junctophilin-2 (JP-2) (Junctophilin type 2) [Cleaved into: Junctophilin-2 N-terminal fragment (JP2NT)] Homo sapiens (Human) calcium ion homeostasis [GO:0055074]; calcium ion transport into cytosol [GO:0060402]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of ryanodine-sensitive calcium-release channel activity [GO:0060316]; regulation of cardiac muscle tissue development [GO:0055024]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314] GO:0000122; GO:0001046; GO:0001227; GO:0001786; GO:0003677; GO:0005546; GO:0005547; GO:0005634; GO:0005789; GO:0005886; GO:0010314; GO:0014701; GO:0016529; GO:0030018; GO:0030314; GO:0032266; GO:0045892; GO:0055024; GO:0055074; GO:0060314; GO:0060316; GO:0060402; GO:0070273; GO:0070300; GO:0080025 24035 FUN_036263 1335 1113 926 1145 719 ptg000025l:17278244-17285943 O00370 4.5e-23 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 24036 FUN_023124 26 9 5 35 52 NA NA NA NA NA NA NA 24037 FUN_038127 580 623 743 1052 375 NA NA NA NA NA NA NA 24038 FUN_036268 24 0 65 0 0 NA NA NA NA NA NA NA 24039 FUN_023125 62 0 0 78 29 NA NA NA NA NA NA NA 24040 FUN_023126 178 0 33 202 198 NA NA NA NA NA NA NA 24041 FUN_037798 140 78 135 275 219 NA NA NA NA NA NA NA 24042 FUN_037799 509 373 134 673 429 NA NA NA NA NA NA NA 24043 FUN_037796 2562 2015 1452 2829 1981 ptg000026l:13665945-13679482 Q98SP7 1.01e-31 Bardet-Biedl syndrome 2 protein homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; determination of left/right symmetry [GO:0007368]; gastrulation [GO:0007369]; intracellular transport [GO:0046907]; Kupffer's vesicle development [GO:0070121]; melanosome transport [GO:0032402]; non-motile cilium assembly [GO:1905515]; pigment granule aggregation in cell center [GO:0051877] GO:0005737; GO:0007368; GO:0007369; GO:0016020; GO:0031514; GO:0032402; GO:0034464; GO:0036064; GO:0043005; GO:0046907; GO:0051877; GO:0060170; GO:0060271; GO:0070121; GO:1905515 24044 FUN_037797 12 0 18 7 16 NA NA NA NA NA NA NA 24045 FUN_037794 856 824 570 955 971 NA NA NA NA NA NA NA 24046 FUN_028715 11 0 0 0 56 NA NA NA NA NA NA NA 24047 FUN_037792 15 9 41 7 0 NA NA NA NA NA NA NA 24048 FUN_037793 185 237 478 499 243 NA NA NA NA NA NA NA 24049 FUN_037790 1711 1120 1050 1704 756 NA NA NA NA NA NA NA 24050 FUN_037791 857 105 253 403 116 NA NA NA NA NA NA NA 24051 FUN_027443 0 0 22 0 0 NA NA NA NA NA NA NA 24052 FUN_027442 0 31 24 0 0 NA NA NA NA NA NA NA 24053 FUN_027441 0 0 22 0 0 NA NA NA NA NA NA NA 24054 FUN_027440 0 22 35 0 0 NA NA NA NA NA NA NA 24055 FUN_027446 39 40 14 27 0 NA NA NA NA NA NA NA 24056 FUN_037586 2000 869 1088 1659 1388 NA NA NA NA NA NA NA 24057 FUN_037138 0 0 6 0 40 NA NA NA NA NA NA NA 24058 FUN_037139 11 39 21 4 1 NA NA NA NA NA NA NA 24059 FUN_037132 30 0 0 0 4 NA NA NA NA NA NA NA 24060 FUN_037133 0 6 0 5 38 NA NA NA NA NA NA NA 24061 FUN_037130 86 50 197 384 698 ptg000026l:6160485-6163671 P0CI65 8.58e-49 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24062 FUN_037130 86 50 197 384 698 ptg000026l:6160485-6163671 P0CI65 6.68e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 24063 FUN_037131 91 38 65 0 84 NA NA NA NA NA NA NA 24064 FUN_037137 543 22 217 187 239 ptg000026l:6229704-6242532 Q7Z494 2.31e-40 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 24065 FUN_037137 543 22 217 187 239 ptg000026l:6229704-6242532 Q7Z494 4.35e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 24066 FUN_037137 543 22 217 187 239 ptg000026l:6229704-6242532 Q7Z494 4.82e-29 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 24067 FUN_037134 280 24 54 17 171 NA NA NA NA NA NA NA 24068 FUN_037135 0 9 7 6 12 ptg000026l:6208737-6210272 A0A2J6RX17 1.68e-42 NA NA NA NA 24069 FUN_037135 0 9 7 6 12 ptg000026l:6208737-6210272 A0A2J6RX17 3.37e-38 NA NA NA NA 24070 FUN_037135 0 9 7 6 12 ptg000026l:6208737-6210272 A0A2J6RX17 4.14e-36 NA NA NA NA 24071 FUN_006635 2943 2259 1503 2693 2314 NA NA NA NA NA NA NA 24072 FUN_006634 3410 2125 2462 2955 3002 ptg000001l:14921055-14961938 P21328 1.73e-32 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 24073 FUN_006637 2101 1212 805 2258 1297 NA NA NA NA NA NA NA 24074 FUN_006636 2702 1948 1889 3877 2404 NA NA NA NA NA NA NA 24075 FUN_006631 1046 410 622 1198 927 NA NA NA NA NA NA NA 24076 FUN_006630 166 106 43 89 78 NA NA NA NA NA NA NA 24077 FUN_006633 53 47 46 54 75 NA NA NA NA NA NA NA 24078 FUN_006632 1305 1401 749 2358 1428 ptg000001l:14896236-14917337 Q66H60 2.09e-29 Coiled-coil domain-containing protein 146 Rattus norvegicus (Rat) NA GO:0005737; GO:0005814; GO:0005856 24079 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 3.47e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24080 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 5.07e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24081 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 5.07e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24082 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 5.07e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24083 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 7.16e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24084 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 7.16e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24085 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 1.7e-31 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24086 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 1.29e-24 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24087 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 1.58e-22 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24088 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 1.58e-22 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24089 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 2.19e-22 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24090 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 2.19e-22 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24091 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 4.15e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24092 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 4.15e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24093 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 5.27e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24094 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 5.27e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24095 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 9.71e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24096 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 9.71e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24097 FUN_032568 2133 1103 791 1753 1692 ptg000023l:33268933-33301462 Q03650 9.71e-21 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 24098 FUN_032569 11145 6830 3625 9395 6579 ptg000023l:33303515-33308485 Q5M7N9 1.29e-82 Extended synaptotagmin-3 (E-Syt3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endoplasmic reticulum-plasma membrane tethering [GO:0061817]; lipid transport [GO:0006869] GO:0005789; GO:0005886; GO:0006869; GO:0008289; GO:0046872; GO:0061817; GO:0140268 24099 FUN_006639 4906 3251 2425 3965 3326 NA NA NA NA NA NA NA 24100 FUN_006638 5605 3586 3322 5267 4596 ptg000001l:15031238-15040943 Q5NVM7 9.76e-38 Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005789; GO:0015031 24101 FUN_006638 5605 3586 3322 5267 4596 ptg000001l:15031238-15040943 Q5NVM7 9.76e-38 Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005789; GO:0015031 24102 FUN_006638 5605 3586 3322 5267 4596 ptg000001l:15031238-15040943 Q5NVM7 2.01e-26 Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005789; GO:0015031 24103 FUN_003579 4 2 0 20 4 NA NA NA NA NA NA NA 24104 FUN_003578 223 118 62 333 80 NA NA NA NA NA NA NA 24105 FUN_004709 1959 1125 879 2291 1452 NA NA NA NA NA NA NA 24106 FUN_004706 39 4 6 28 7 NA NA NA NA NA NA NA 24107 FUN_003577 31 9 31 68 28 NA NA NA NA NA NA NA 24108 FUN_003576 161 57 109 243 86 NA NA NA NA NA NA NA 24109 FUN_004703 34 37 14 18 25 NA NA NA NA NA NA NA 24110 FUN_003570 0 21 54 62 38 NA NA NA NA NA NA NA 24111 FUN_004701 275 334 165 555 448 NA NA NA NA NA NA NA 24112 FUN_003572 0 0 0 6 12 NA NA NA NA NA NA NA 24113 FUN_026674 0 31 96 92 96 ptg000020l:12286776-12292108 Q9JLC8 7.63e-53 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 24114 FUN_011858 57 51 24 130 76 NA NA NA NA NA NA NA 24115 FUN_041854 1207 793 627 776 1076 NA NA NA NA NA NA NA 24116 FUN_001368 55 24 35 34 41 NA NA NA NA NA NA NA 24117 FUN_001369 2142 1313 1117 1765 1555 ntLink_6:11563957-11578743 Q05586 1.98e-26 Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Homo sapiens (Human) brain development [GO:0007420]; calcium ion homeostasis [GO:0055074]; calcium ion transmembrane import into cytosol [GO:0097553]; cation transmembrane transport [GO:0098655]; cation transport [GO:0006812]; chemical synaptic transmission [GO:0007268]; excitatory chemical synaptic transmission [GO:0098976]; excitatory postsynaptic potential [GO:0060079]; ionotropic glutamate receptor signaling pathway [GO:0035235]; positive regulation of calcium ion transport into cytosol [GO:0010524]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of excitatory postsynaptic potential [GO:2000463]; positive regulation of reactive oxygen species biosynthetic process [GO:1903428]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transcription by RNA polymerase II [GO:0045944]; propylene metabolic process [GO:0018964]; protein heterotetramerization [GO:0051290]; regulation of cation transmembrane transport [GO:1904062]; regulation of membrane potential [GO:0042391]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of synaptic plasticity [GO:0048167]; response to ethanol [GO:0045471]; response to glycine [GO:1905429]; visual learning [GO:0008542] GO:0001540; GO:0004972; GO:0005509; GO:0005516; GO:0005737; GO:0005789; GO:0005886; GO:0006812; GO:0007268; GO:0007420; GO:0008021; GO:0008542; GO:0009986; GO:0010524; GO:0014069; GO:0015276; GO:0016594; GO:0016595; GO:0017146; GO:0018964; GO:0022849; GO:0030425; GO:0035235; GO:0038023; GO:0042165; GO:0042391; GO:0043005; GO:0043083; GO:0043195; GO:0043197; GO:0044877; GO:0045202; GO:0045211; GO:0045471; GO:0045944; GO:0048167; GO:0048168; GO:0051290; GO:0051968; GO:0055074; GO:0060076; GO:0060079; GO:0097060; GO:0097553; GO:0098655; GO:0098976; GO:1903428; GO:1904062; GO:1905429; GO:2000463; GO:2001056 24118 FUN_041850 31774 29743 24801 30820 18233 NA NA NA NA NA NA NA 24119 FUN_041851 8132 7503 6273 7343 5541 NA NA NA NA NA NA NA 24120 FUN_041852 1997 1720 1254 1513 1099 ptg000035l:8239950-8244764 P14381 2.11e-59 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24121 FUN_041853 5443 6118 3478 4115 2972 NA NA NA NA NA NA NA 24122 FUN_001363 0 0 0 0 42 NA NA NA NA NA NA NA 24123 FUN_001360 34 59 42 91 74 ntLink_6:11485974-11496972 P04323 1.68e-54 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24124 FUN_001361 1220 223 911 819 2792 NA NA NA NA NA NA NA 24125 FUN_041858 19 0 0 8 8 NA NA NA NA NA NA NA 24126 FUN_001367 2200 3071 1605 1778 1864 NA NA NA NA NA NA NA 24127 FUN_001364 1028 515 629 1074 1032 NA NA NA NA NA NA NA 24128 FUN_001365 3332 4419 1213 4165 1444 ntLink_6:11530351-11531128 Q9QYI5 3.01e-42 DnaJ homolog subfamily B member 2 (DnaJ homolog subfamily B member 10) (mDj8) Mus musculus (Mouse) chaperone-mediated protein folding [GO:0061077]; negative regulation of cell growth [GO:0030308]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of inclusion body assembly [GO:0090084]; negative regulation of protein binding [GO:0032091]; negative regulation of protein deubiquitination [GO:0090086]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein refolding [GO:0042026]; regulation of chaperone-mediated protein folding [GO:1903644]; regulation of protein localization [GO:0032880]; regulation of protein ubiquitination [GO:0031396]; ubiquitin-dependent ERAD pathway [GO:0030433] GO:0000502; GO:0001671; GO:0005634; GO:0005737; GO:0005789; GO:0005829; GO:0008285; GO:0016234; GO:0030308; GO:0030433; GO:0030544; GO:0031396; GO:0031398; GO:0031593; GO:0031625; GO:0031965; GO:0032091; GO:0032436; GO:0032781; GO:0032880; GO:0042026; GO:0043130; GO:0043161; GO:0048471; GO:0051082; GO:0051087; GO:0061077; GO:0070628; GO:0090084; GO:0090086; GO:0140036; GO:1903644 24129 FUN_002622 4 26 54 40 18 NA NA NA NA NA NA NA 24130 FUN_002620 0 0 0 39 22 NA NA NA NA NA NA NA 24131 FUN_002621 1458 7754 104 2279 292 NA NA NA NA NA NA NA 24132 FUN_002626 29 108 92 98 78 NA NA NA NA NA NA NA 24133 FUN_002627 152 0 55 0 0 NA NA NA NA NA NA NA 24134 FUN_002624 6 47 42 50 86 NA NA NA NA NA NA NA 24135 FUN_011136 0 0 32 0 26 NA NA NA NA NA NA NA 24136 FUN_011134 0 0 0 0 35 NA NA NA NA NA NA NA 24137 FUN_011135 0 0 0 11 43 NA NA NA NA NA NA NA 24138 FUN_011132 12 9 25 0 220 NA NA NA NA NA NA NA 24139 FUN_011133 0 0 0 0 32 NA NA NA NA NA NA NA 24140 FUN_011131 1183 0 243 13 0 NA NA NA NA NA NA NA 24141 FUN_011680 2924 1342 930 2228 1938 ptg000008l:96486-126617 P14381 2.08e-97 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24142 FUN_011681 4789 2765 2233 3425 2674 NA NA NA NA NA NA NA 24143 FUN_011682 385 103 327 307 218 ptg000008l:152387-153845 P49288 1.78e-25 Melatonin receptor type 1C (Mel-1C-R) (Mel1c receptor) (CKB) Gallus gallus (Chicken) G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of glucose import [GO:0046325]; negative regulation of glycolytic process [GO:0045820] GO:0004930; GO:0005654; GO:0005886; GO:0007186; GO:0008502; GO:0045820; GO:0046325; GO:1904408 24144 FUN_011684 842 52 91 152 107 NA NA NA NA NA NA NA 24145 FUN_011685 144 47 53 163 72 ptg000008l:181829-185050 A3BF39 7.68e-51 Cadmium/zinc-transporting ATPase HMA2 (EC 7.2.2.12) (EC 7.2.2.21) (Protein HEAVY METAL ATPASE 2) (OsHMA2) Oryza sativa subsp. japonica (Rice) NA GO:0005385; GO:0005524; GO:0005886; GO:0008551; GO:0015086; GO:0016463; GO:0016887; GO:0046872 24146 FUN_011686 382 325 341 252 264 NA NA NA NA NA NA NA 24147 FUN_011687 16 6 7 12 6 NA NA NA NA NA NA NA 24148 FUN_011689 2362 1625 948 3140 3037 NA NA NA NA NA NA NA 24149 FUN_012798 14 0 22 24 57 NA NA NA NA NA NA NA 24150 FUN_012796 532 50 377 370 575 NA NA NA NA NA NA NA 24151 FUN_029454 0 0 0 0 219 NA NA NA NA NA NA NA 24152 FUN_029452 881 771 174 459 336 NA NA NA NA NA NA NA 24153 FUN_012792 4797 4791 1686 3353 2501 NA NA NA NA NA NA NA 24154 FUN_012791 159 60 134 168 250 ptg000008l:12883696-12886829 Q8R1Q9 1.31e-21 Ribokinase (RK) (EC 2.7.1.15) Mus musculus (Mouse) D-ribose catabolic process [GO:0019303]; pentose-phosphate shunt [GO:0006098] GO:0004747; GO:0005524; GO:0005634; GO:0005829; GO:0006098; GO:0019303; GO:0042802; GO:0046872 24155 FUN_016489 4015 2231 1408 2840 1947 NA NA NA NA NA NA NA 24156 FUN_016488 15786 12113 6304 12143 9770 NA NA NA NA NA NA NA 24157 FUN_016487 82 123 35 85 52 NA NA NA NA NA NA NA 24158 FUN_016486 2650 1780 1191 2200 1346 NA NA NA NA NA NA NA 24159 FUN_016485 79 5 20 43 18 NA NA NA NA NA NA NA 24160 FUN_016484 21378 23398 11190 15833 11466 NA NA NA NA NA NA NA 24161 FUN_016483 0 30 0 132 50 NA NA NA NA NA NA NA 24162 FUN_016482 17 0 14 6 36 NA NA NA NA NA NA NA 24163 FUN_016481 216 254 94 334 253 NA NA NA NA NA NA NA 24164 FUN_040812 17 4 0 32 19 NA NA NA NA NA NA NA 24165 FUN_025652 24 32 28 33 31 NA NA NA NA NA NA NA 24166 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 1.73e-49 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24167 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 2.11e-36 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24168 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 7.13e-36 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24169 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 6.66e-31 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24170 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 9.84e-31 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24171 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 2.7e-25 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24172 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 9.93e-24 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24173 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 5.52e-23 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24174 FUN_043548 2742 3043 3266 5560 3788 ptg000047l:9754346-9771324 B3EWZ9 5.66e-21 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24175 FUN_043549 1157 494 340 1248 1068 NA NA NA NA NA NA NA 24176 FUN_043544 953 766 327 459 777 ptg000047l:9727093-9730921 Q7SYK1 6.46e-23 Queuine tRNA-ribosyltransferase catalytic subunit 1 (EC 2.4.2.64) (Guanine insertion enzyme) (tRNA-guanine transglycosylase) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA-guanine transglycosylation [GO:0101030] GO:0005741; GO:0008479; GO:0042803; GO:0046872; GO:0046982; GO:0101030 24177 FUN_043545 352 564 545 645 324 ptg000047l:9731724-9734077 Q3TQI7 8.29e-27 Splicing factor C9orf78 homolog Mus musculus (Mouse) chromosome segregation [GO:0007059]; mRNA cis splicing, via spliceosome [GO:0045292]; mRNA splicing, via spliceosome [GO:0000398]; regulation of homologous chromosome segregation [GO:0060629] GO:0000398; GO:0000775; GO:0005634; GO:0005654; GO:0005681; GO:0005829; GO:0007059; GO:0030623; GO:0045292; GO:0060629 24178 FUN_043546 238 153 56 78 188 NA NA NA NA NA NA NA 24179 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 6.81e-48 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24180 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 1.57e-35 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24181 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 1.32e-34 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24182 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 2.09e-31 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24183 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 2.75e-30 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24184 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 8.1e-26 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24185 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 3.12e-23 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24186 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 3.37e-23 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24187 FUN_043547 4758 2169 289 3261 5093 ptg000047l:9737275-9752473 B3EWZ9 5.28e-21 Hephaestin-like protein (EC 1.-.-.-) Acropora millepora (Staghorn coral) (Heteropora millepora) copper ion transport [GO:0006825] GO:0005507; GO:0005576; GO:0006825; GO:0016020; GO:0016491 24188 FUN_043540 872 659 448 789 630 NA NA NA NA NA NA NA 24189 FUN_043541 1155 974 331 656 978 NA NA NA NA NA NA NA 24190 FUN_043542 0 20 0 0 0 NA NA NA NA NA NA NA 24191 FUN_043543 171 124 145 144 156 ptg000047l:9717925-9724785 Q8R2T8 6.52e-21 General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon) Mus musculus (Mouse) skeletal muscle cell differentiation [GO:0035914]; transcription initiation at RNA polymerase III promoter [GO:0006384] GO:0000127; GO:0000995; GO:0003677; GO:0005654; GO:0006384; GO:0035914 24192 FUN_007972 27 0 9 39 52 NA NA NA NA NA NA NA 24193 FUN_009368 30 26 35 112 19 NA NA NA NA NA NA NA 24194 FUN_025653 257 185 154 205 99 NA NA NA NA NA NA NA 24195 FUN_002197 82 53 45 91 103 NA NA NA NA NA NA NA 24196 FUN_002334 295 0 204 217 54 NA NA NA NA NA NA NA 24197 FUN_002337 418 8 66 413 297 ntLink_8:174038-184329 Q96AY4 2.48e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24198 FUN_002337 418 8 66 413 297 ntLink_8:174038-184329 Q96AY4 6.85e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24199 FUN_002337 418 8 66 413 297 ntLink_8:174038-184329 Q96AY4 4.76e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24200 FUN_002337 418 8 66 413 297 ntLink_8:174038-184329 Q96AY4 1.49e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24201 FUN_002337 418 8 66 413 297 ntLink_8:174038-184329 Q96AY4 3.24e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24202 FUN_002330 425 0 353 291 262 NA NA NA NA NA NA NA 24203 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 7.82e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24204 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 2.08e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24205 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 4.32e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24206 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 7.95e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24207 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 1.89e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24208 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 1.01e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24209 FUN_002331 1383 10 87 293 86 ntLink_8:91210-96162 Q96AY4 5.3e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24210 FUN_035354 1203 0 483 534 513 ptg000025l:6656076-6666554 Q5REG4 1.64e-29 Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (RING-type E3 ubiquitin transferase DTX3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Notch signaling pathway [GO:0007219]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007219; GO:0016567; GO:0016740; GO:0046872 24211 FUN_002333 1232 8 86 958 431 ntLink_8:126829-130684 Q96AY4 1.32e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24212 FUN_002333 1232 8 86 958 431 ntLink_8:126829-130684 Q96AY4 5.8e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24213 FUN_002333 1232 8 86 958 431 ntLink_8:126829-130684 Q96AY4 2.77e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24214 FUN_002333 1232 8 86 958 431 ntLink_8:126829-130684 Q96AY4 2.76e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24215 FUN_023119 2412 1053 779 1950 1250 ptg000017l:3863195-3877718 Q6ZQF0 3.06e-86 DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA replication initiation [GO:0006270]; homologous recombination [GO:0035825]; mitotic DNA replication checkpoint signaling [GO:0033314]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; reciprocal meiotic recombination [GO:0007131]; response to ionizing radiation [GO:0010212] GO:0000794; GO:0000922; GO:0001673; GO:0003677; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005815; GO:0005886; GO:0006270; GO:0006281; GO:0006974; GO:0007095; GO:0007131; GO:0010212; GO:0015629; GO:0016604; GO:0016605; GO:0033314; GO:0035825; GO:0042802; GO:0043231; GO:0070532 24216 FUN_023118 74 20 20 117 117 ptg000017l:3854892-3856476 Q80UN9 7.5e-72 tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase) Mus musculus (Mouse) mitochondrial tRNA modification [GO:0070900]; tRNA modification [GO:0006400] GO:0005524; GO:0005634; GO:0005739; GO:0006400; GO:0046872; GO:0052381; GO:0070900 24217 FUN_023118 74 20 20 117 117 ptg000017l:3854892-3856476 Q80UN9 3.14e-43 tRNA dimethylallyltransferase (EC 2.5.1.75) (Isopentenyl-diphosphate:tRNA isopentenyltransferase) (IPP transferase) (IPPT) (tRNA isopentenyltransferase) (IPTase) Mus musculus (Mouse) mitochondrial tRNA modification [GO:0070900]; tRNA modification [GO:0006400] GO:0005524; GO:0005634; GO:0005739; GO:0006400; GO:0046872; GO:0052381; GO:0070900 24218 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 6.08e-56 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24219 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 4.15e-48 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24220 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 1.72e-47 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24221 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 2.67e-47 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24222 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 3.22e-47 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24223 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 1.53e-39 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24224 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 2.3e-35 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24225 FUN_023115 209 167 112 239 207 ptg000017l:3822827-3823868 Q68EA5 3.14e-30 Zinc finger protein 57 (Zinc finger protein 424) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 24226 FUN_023114 22 25 7 11 4 ptg000017l:3815674-3816661 G3M4F8 3.15e-21 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 24227 FUN_023117 1221 375 514 976 669 NA NA NA NA NA NA NA 24228 FUN_023116 0 0 23 59 9 NA NA NA NA NA NA NA 24229 FUN_023111 2496 1303 1550 3516 3615 NA NA NA NA NA NA NA 24230 FUN_023110 1856 2211 1547 2560 1421 NA NA NA NA NA NA NA 24231 FUN_023113 996 869 649 1006 799 ptg000017l:3804940-3807376 Q5ZJN2 7.28e-41 Ras-related protein Rab-11A (EC 3.6.5.2) Gallus gallus (Chicken) cell cycle [GO:0007049]; exocytosis [GO:0006887]; melanosome transport [GO:0032402]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005794; GO:0006887; GO:0007049; GO:0016192; GO:0030133; GO:0032154; GO:0032402; GO:0045335; GO:0055037; GO:0055038; GO:0098837; GO:0098887 24232 FUN_023113 996 869 649 1006 799 ptg000017l:3804940-3807376 Q5ZJN2 4.79e-24 Ras-related protein Rab-11A (EC 3.6.5.2) Gallus gallus (Chicken) cell cycle [GO:0007049]; exocytosis [GO:0006887]; melanosome transport [GO:0032402]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005794; GO:0006887; GO:0007049; GO:0016192; GO:0030133; GO:0032154; GO:0032402; GO:0045335; GO:0055037; GO:0055038; GO:0098837; GO:0098887 24233 FUN_023112 6720 5656 3890 12172 7467 ptg000017l:3798886-3802227 Q32NS4 1.79e-27 E3 ubiquitin-protein ligase arih1 (EC 2.3.2.31) (Protein ariadne-1 homolog) (ARI-1) (RING-type E3 ubiquitin transferase arih1) Xenopus laevis (African clawed frog) protein ubiquitination [GO:0016567] GO:0004842; GO:0005737; GO:0008270; GO:0016567; GO:0016604; GO:0097413 24234 FUN_019728 0 0 33 0 105 NA NA NA NA NA NA NA 24235 FUN_014997 0 0 0 11 14 NA NA NA NA NA NA NA 24236 FUN_002724 1323 1920 823 1050 684 NA NA NA NA NA NA NA 24237 FUN_014849 290 151 142 92 130 ptg000009l:3680736-3685738 Q03206 1.08e-52 Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1) Caenorhabditis elegans actin filament organization [GO:0007015]; apoptotic process [GO:0006915]; axon extension involved in axon guidance [GO:0048846]; axon regeneration [GO:0031103]; body morphogenesis [GO:0010171]; cell migration [GO:0016477]; chemorepulsion of axon [GO:0061643]; cortical cytoskeleton organization [GO:0030865]; distal tip cell migration [GO:0097628]; dorsal/ventral axon guidance [GO:0033563]; embryonic body morphogenesis [GO:0010172]; embryonic morphogenesis [GO:0048598]; engulfment of apoptotic cell [GO:0043652]; establishment of mitotic spindle orientation [GO:0000132]; establishment or maintenance of actin cytoskeleton polarity [GO:0030950]; establishment or maintenance of cell polarity [GO:0007163]; gastrulation [GO:0007369]; left/right axis specification [GO:0070986]; motor neuron axon guidance [GO:0008045]; negative regulation of microtubule polymerization [GO:0031115]; nematode larval development [GO:0002119]; nematode male tail tip morphogenesis [GO:0045138]; netrin-activated signaling pathway [GO:0038007]; neuron migration [GO:0001764]; neuron projection morphogenesis [GO:0048812]; positive regulation of distal tip cell migration [GO:1903356]; positive regulation of engulfment of apoptotic cell [GO:1901076]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell migration [GO:0030334]; regulation of cell shape [GO:0008360]; regulation of dorsal/ventral axon guidance [GO:1905815]; regulation of phagocytosis [GO:0050764]; regulation of synaptic transmission, GABAergic [GO:0032228]; small GTPase mediated signal transduction [GO:0007264] GO:0000132; GO:0001764; GO:0002119; GO:0003924; GO:0005525; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0006915; GO:0007015; GO:0007163; GO:0007264; GO:0007369; GO:0008045; GO:0008360; GO:0009898; GO:0010171; GO:0010172; GO:0016020; GO:0016477; GO:0019901; GO:0030334; GO:0030865; GO:0030950; GO:0031103; GO:0031115; GO:0031410; GO:0032228; GO:0032956; GO:0033563; GO:0038007; GO:0042995; GO:0043005; GO:0043025; GO:0043652; GO:0045138; GO:0048598; GO:0048812; GO:0048846; GO:0050764; GO:0061643; GO:0070986; GO:0097628; GO:1901076; GO:1903356; GO:1905815 24238 FUN_014848 2167 1359 1327 990 501 ptg000009l:3678925-3680218 Q9XWN7 5.43e-25 Nucleoside hydrolase (EC 3.2.2.-) (EC 3.2.2.1) (EC 3.2.2.2) (EC 3.2.2.3) (EC 3.2.2.7) (EC 3.2.2.8) Caenorhabditis elegans nucleobase-containing compound metabolic process [GO:0006139]; organonitrogen compound metabolic process [GO:1901564] GO:0006139; GO:0016799; GO:0046872; GO:1901564 24239 FUN_041036 0 0 0 0 199 NA NA NA NA NA NA NA 24240 FUN_041037 28 4 16 28 199 NA NA NA NA NA NA NA 24241 FUN_041034 6 0 3 0 0 NA NA NA NA NA NA NA 24242 FUN_028492 5 0 17 2 92 ptg000021l:20662251-20662770 P23348 2.64e-21 Anion exchange protein 3 (AE 3) (Anion exchanger 3) (Band 3-related protein 3) (B3RP-3) (Neuronal band 3-like protein) (Solute carrier family 4 member 3) Rattus norvegicus (Rat) anion transmembrane transport [GO:0098656]; bicarbonate transport [GO:0015701]; cardiac conduction [GO:0061337]; ion homeostasis [GO:0050801]; regulation of intracellular pH [GO:0051453]; transmembrane transport [GO:0055085] GO:0005886; GO:0009897; GO:0015106; GO:0015701; GO:0019899; GO:0022857; GO:0050801; GO:0051453; GO:0055085; GO:0061337; GO:0098656; GO:0140900 24243 FUN_028495 5147 5885 3742 3663 1970 NA NA NA NA NA NA NA 24244 FUN_028494 1507 761 777 1953 1159 ptg000021l:20665634-20675798 Q96MW5 7.55e-22 Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8) Homo sapiens (Human) glycosylation [GO:0070085]; Golgi organization [GO:0007030]; intra-Golgi vesicle-mediated transport [GO:0006891]; protein transport [GO:0015031]; retrograde transport, vesicle recycling within Golgi [GO:0000301] GO:0000139; GO:0000301; GO:0005794; GO:0006891; GO:0007030; GO:0015031; GO:0016020; GO:0017119; GO:0032588; GO:0070085 24245 FUN_028497 1318 985 493 1360 822 NA NA NA NA NA NA NA 24246 FUN_028496 98 80 103 57 137 NA NA NA NA NA NA NA 24247 FUN_028499 381 60 58 123 113 NA NA NA NA NA NA NA 24248 FUN_028498 2077 1707 1392 2265 2620 ptg000021l:20693914-20719339 Q6PDH0 3.12e-33 Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha) Mus musculus (Mouse) positive regulation of basement membrane assembly involved in embryonic body morphogenesis [GO:1904261]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gastrulation [GO:0010470]; regulation of microtubule cytoskeleton organization [GO:0070507] GO:0005829; GO:0005886; GO:0010470; GO:0010717; GO:0043231; GO:0045171; GO:0045180; GO:0070507; GO:1904261 24249 FUN_000524 0 0 0 0 21 NA NA NA NA NA NA NA 24250 FUN_041038 35 0 23 0 37 ptg000034l:204330-207304 P22843 4.34e-74 Histone H3 Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24251 FUN_014845 2099 1623 898 1628 154 NA NA NA NA NA NA NA 24252 FUN_009399 64 18 58 66 160 ptg000004l:6378865-6390500 B8VIU6 8.89e-30 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24253 FUN_009398 10 0 0 0 17 NA NA NA NA NA NA NA 24254 FUN_009397 0 126 0 0 8 ptg000004l:6364128-6365331 B8VIU6 2.89e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24255 FUN_009396 0 0 6 0 44 NA NA NA NA NA NA NA 24256 FUN_009395 0 0 7 0 41 NA NA NA NA NA NA NA 24257 FUN_009394 0 0 0 6 0 ptg000004l:6337386-6338242 B8VIU6 1.93e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24258 FUN_009393 0 21 0 0 0 NA NA NA NA NA NA NA 24259 FUN_000529 1694 1592 1012 2888 937 ntLink_6:4016407-4025998 P17336 1.82e-39 Catalase (EC 1.11.1.6) Drosophila melanogaster (Fruit fly) aging [GO:0007568]; determination of adult lifespan [GO:0008340]; heart morphogenesis [GO:0003007]; hydrogen peroxide catabolic process [GO:0042744]; intestinal stem cell homeostasis [GO:0036335]; paracrine signaling [GO:0038001]; reactive oxygen species metabolic process [GO:0072593]; regulation of hemocyte proliferation [GO:0035206]; regulation of synaptic plasticity [GO:0048167]; response to endoplasmic reticulum stress [GO:0034976]; response to hydrogen peroxide [GO:0042542] GO:0003007; GO:0004096; GO:0005737; GO:0005739; GO:0005777; GO:0007568; GO:0008340; GO:0020037; GO:0034976; GO:0035206; GO:0036335; GO:0038001; GO:0042542; GO:0042744; GO:0046872; GO:0048167; GO:0072593 24260 FUN_000529 1694 1592 1012 2888 937 ntLink_6:4016407-4025998 P17336 8.64e-26 Catalase (EC 1.11.1.6) Drosophila melanogaster (Fruit fly) aging [GO:0007568]; determination of adult lifespan [GO:0008340]; heart morphogenesis [GO:0003007]; hydrogen peroxide catabolic process [GO:0042744]; intestinal stem cell homeostasis [GO:0036335]; paracrine signaling [GO:0038001]; reactive oxygen species metabolic process [GO:0072593]; regulation of hemocyte proliferation [GO:0035206]; regulation of synaptic plasticity [GO:0048167]; response to endoplasmic reticulum stress [GO:0034976]; response to hydrogen peroxide [GO:0042542] GO:0003007; GO:0004096; GO:0005737; GO:0005739; GO:0005777; GO:0007568; GO:0008340; GO:0020037; GO:0034976; GO:0035206; GO:0036335; GO:0038001; GO:0042542; GO:0042744; GO:0046872; GO:0048167; GO:0072593 24261 FUN_009391 0 9 0 0 0 ptg000004l:6306805-6307385 B8VIU6 9.75e-37 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24262 FUN_009390 436 733 189 56 262 NA NA NA NA NA NA NA 24263 FUN_011918 5268 3967 2803 4596 2968 NA NA NA NA NA NA NA 24264 FUN_011919 1366 1564 953 1166 555 NA NA NA NA NA NA NA 24265 FUN_011910 108 48 0 74 164 ptg000008l:2811919-2815591 Q1L908 4.85e-45 Protein misato homolog 1 Danio rerio (Zebrafish) (Brachydanio rerio) mitochondrion organization [GO:0007005] GO:0005737; GO:0005739; GO:0005741; GO:0007005 24266 FUN_011911 2823 3494 1966 2309 1820 NA NA NA NA NA NA NA 24267 FUN_011912 1316 406 779 781 923 NA NA NA NA NA NA NA 24268 FUN_011913 292 198 109 254 177 ptg000008l:3042504-3044950 Q5F2N3 3.78e-26 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Danio rerio (Zebrafish) (Brachydanio rerio) fucosylation [GO:0036065]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0036065; GO:0046920 24269 FUN_011914 21 8 12 414 632 NA NA NA NA NA NA NA 24270 FUN_011915 495 586 298 450 1615 NA NA NA NA NA NA NA 24271 FUN_011916 9077 6609 3744 5137 9863 NA NA NA NA NA NA NA 24272 FUN_014840 9 12 10 29 6 NA NA NA NA NA NA NA 24273 FUN_035454 8 22 13 48 51 NA NA NA NA NA NA NA 24274 FUN_005419 0 12 0 8 19 NA NA NA NA NA NA NA 24275 FUN_022642 40 0 46 41 189 NA NA NA NA NA NA NA 24276 FUN_022640 474 360 268 260 208 ptg000016l:11760962-11762171 P49356 1.85e-161 Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) Homo sapiens (Human) lipid metabolic process [GO:0006629]; protein farnesylation [GO:0018343]; protein prenylation [GO:0018342] GO:0004660; GO:0005829; GO:0005875; GO:0005965; GO:0006629; GO:0008270; GO:0018342; GO:0018343 24277 FUN_022641 23 0 30 7 157 NA NA NA NA NA NA NA 24278 FUN_022644 614 799 1331 1810 2734 NA NA NA NA NA NA NA 24279 FUN_022648 29 8 28 48 47 NA NA NA NA NA NA NA 24280 FUN_022649 3688 2591 1772 4120 2983 NA NA NA NA NA NA NA 24281 FUN_024561 2132 2512 1308 1549 1220 NA NA NA NA NA NA NA 24282 FUN_008117 370 230 165 414 340 NA NA NA NA NA NA NA 24283 FUN_008114 0 0 17 34 0 NA NA NA NA NA NA NA 24284 FUN_008115 62 82 0 102 232 NA NA NA NA NA NA NA 24285 FUN_024565 52049 58195 39183 55292 37705 NA NA NA NA NA NA NA 24286 FUN_024564 509 344 203 256 523 ptg000018l:8418903-8429190 Q12955 5.18e-22 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 24287 FUN_024564 509 344 203 256 523 ptg000018l:8418903-8429190 Q12955 5.73e-21 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 24288 FUN_024567 364 355 352 231 659 NA NA NA NA NA NA NA 24289 FUN_008111 906 410 1601 1228 1629 NA NA NA NA NA NA NA 24290 FUN_024568 940 825 577 633 302 ptg000018l:8473570-8476864 O95671 2.23e-23 Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein [Includes: dTTP/UTP pyrophosphatase (dTTPase/UTPase) (EC 3.6.1.9) (Nucleoside triphosphate pyrophosphatase) (Nucleotide pyrophosphatase) (Nucleotide PPase); N-acetylserotonin O-methyltransferase-like protein (ASMTL) (EC 2.1.1.-)] Homo sapiens (Human) methylation [GO:0032259]; nucleotide metabolic process [GO:0009117] GO:0005829; GO:0008171; GO:0009117; GO:0032259; GO:0036218; GO:0036221; GO:0047429 24291 FUN_008118 226 201 96 231 209 ptg000002l:8221849-8222744 Q9D2V5 3.19e-29 Protein AAR2 homolog (AAR2 splicing factor homolog) Mus musculus (Mouse) spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0005681 24292 FUN_008119 3450 2883 2202 4065 1623 NA NA NA NA NA NA NA 24293 FUN_044126 66 258 110 192 568 NA NA NA NA NA NA NA 24294 FUN_014245 0 0 0 0 11 NA NA NA NA NA NA NA 24295 FUN_014244 16 0 0 0 3 NA NA NA NA NA NA NA 24296 FUN_044122 5 3 17 2 130 NA NA NA NA NA NA NA 24297 FUN_014241 78 11 20 21 49 NA NA NA NA NA NA NA 24298 FUN_044129 80 295 118 221 612 NA NA NA NA NA NA NA 24299 FUN_044128 5 2 18 4 132 NA NA NA NA NA NA NA 24300 FUN_042227 0 0 0 8 0 NA NA NA NA NA NA NA 24301 FUN_001563 92 58 57 59 61 NA NA NA NA NA NA NA 24302 FUN_022394 57 63 23 84 22 NA NA NA NA NA NA NA 24303 FUN_022395 1470 1523 1080 1612 1901 ptg000016l:8593882-8603986 Q4R6V2 2.19e-45 T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; toxin transport [GO:1901998] GO:0003730; GO:0005524; GO:0005813; GO:0005832; GO:0005874; GO:0007339; GO:0009615; GO:0016887; GO:0031681; GO:0032212; GO:0044297; GO:0048027; GO:0048487; GO:0050821; GO:0051082; GO:0061077; GO:0140662; GO:1901998; GO:1904851 24304 FUN_022395 1470 1523 1080 1612 1901 ptg000016l:8593882-8603986 Q4R6V2 1.15e-25 T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; toxin transport [GO:1901998] GO:0003730; GO:0005524; GO:0005813; GO:0005832; GO:0005874; GO:0007339; GO:0009615; GO:0016887; GO:0031681; GO:0032212; GO:0044297; GO:0048027; GO:0048487; GO:0050821; GO:0051082; GO:0061077; GO:0140662; GO:1901998; GO:1904851 24305 FUN_022395 1470 1523 1080 1612 1901 ptg000016l:8593882-8603986 Q4R6V2 4e-22 T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; response to virus [GO:0009615]; toxin transport [GO:1901998] GO:0003730; GO:0005524; GO:0005813; GO:0005832; GO:0005874; GO:0007339; GO:0009615; GO:0016887; GO:0031681; GO:0032212; GO:0044297; GO:0048027; GO:0048487; GO:0050821; GO:0051082; GO:0061077; GO:0140662; GO:1901998; GO:1904851 24306 FUN_022396 1595 778 707 1575 837 NA NA NA NA NA NA NA 24307 FUN_022390 262 367 187 347 318 NA NA NA NA NA NA NA 24308 FUN_022391 51 8 0 16 13 NA NA NA NA NA NA NA 24309 FUN_022393 645 276 81 221 136 NA NA NA NA NA NA NA 24310 FUN_022398 428 229 214 293 227 ptg000016l:8633936-8636462 Q66KD6 2.22e-47 Probable phosphatase phospho2 (EC 3.1.3.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0016791; GO:0046872 24311 FUN_022399 0 0 0 11 2 NA NA NA NA NA NA NA 24312 FUN_022651 46 6 0 87 72 NA NA NA NA NA NA NA 24313 FUN_025606 18 0 0 0 18 NA NA NA NA NA NA NA 24314 FUN_001788 1004 1577 389 835 651 NA NA NA NA NA NA NA 24315 FUN_022653 215 157 63 252 65 NA NA NA NA NA NA NA 24316 FUN_001789 5 0 3 0 20 NA NA NA NA NA NA NA 24317 FUN_022652 16 0 28 29 110 NA NA NA NA NA NA NA 24318 FUN_022655 91 45 10 22 44 NA NA NA NA NA NA NA 24319 FUN_025602 49 76 0 7 60 ptg000019l:4873380-4874309 P79218 3.98e-33 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 24320 FUN_019852 16 0 36 43 36 NA NA NA NA NA NA NA 24321 FUN_019854 0 0 1 0 47 NA NA NA NA NA NA NA 24322 FUN_019858 7 0 4 0 0 NA NA NA NA NA NA NA 24323 FUN_022656 808 603 134 337 197 NA NA NA NA NA NA NA 24324 FUN_015114 13 0 15 11 102 NA NA NA NA NA NA NA 24325 FUN_015115 41 47 23 24 44 NA NA NA NA NA NA NA 24326 FUN_015116 0 0 35 50 39 NA NA NA NA NA NA NA 24327 FUN_015117 0 0 48 47 33 NA NA NA NA NA NA NA 24328 FUN_015110 5394 2731 3072 5347 4371 ptg000009l:6397604-6431228 P20825 2e-59 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24329 FUN_015111 22 10 0 13 0 NA NA NA NA NA NA NA 24330 FUN_015112 1263 690 675 1045 1130 NA NA NA NA NA NA NA 24331 FUN_015113 13 0 23 27 33 NA NA NA NA NA NA NA 24332 FUN_015118 8 0 9 2 65 NA NA NA NA NA NA NA 24333 FUN_015119 55 77 80 38 28 NA NA NA NA NA NA NA 24334 FUN_024554 1052 645 842 932 958 NA NA NA NA NA NA NA 24335 FUN_024555 2365 1470 822 1297 1314 NA NA NA NA NA NA NA 24336 FUN_038533 1479 643 767 1222 1071 ptg000027l:8455579-8459255 P97275 5.32e-178 Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase) Cavia porcellus (Guinea pig) ether lipid biosynthetic process [GO:0008611] GO:0005730; GO:0005777; GO:0005778; GO:0008609; GO:0008611; GO:0071949 24337 FUN_038533 1479 643 767 1222 1071 ptg000027l:8455579-8459255 P97275 3.8e-58 Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase) Cavia porcellus (Guinea pig) ether lipid biosynthetic process [GO:0008611] GO:0005730; GO:0005777; GO:0005778; GO:0008609; GO:0008611; GO:0071949 24338 FUN_038532 4860 7090 3430 4848 1553 ptg000027l:8444107-8444674 O14508 6.8e-26 Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2) Homo sapiens (Human) cellular response to hormone stimulus [GO:0032870]; growth hormone receptor signaling pathway [GO:0060396]; intracellular signal transduction [GO:0035556]; lactation [GO:0007595]; mammary gland alveolus development [GO:0060749]; negative regulation of apoptotic process [GO:0043066]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; phosphatidylinositol phosphate biosynthetic process [GO:0046854]; positive regulation of neuron differentiation [GO:0045666]; protein ubiquitination [GO:0016567]; receptor signaling pathway via JAK-STAT [GO:0007259]; regulation of cell growth [GO:0001558]; regulation of signal transduction [GO:0009966]; response to estradiol [GO:0032355] GO:0001558; GO:0005131; GO:0005159; GO:0005737; GO:0005829; GO:0005942; GO:0007259; GO:0007595; GO:0008269; GO:0009966; GO:0016567; GO:0032355; GO:0032870; GO:0035556; GO:0040015; GO:0043066; GO:0045666; GO:0046426; GO:0046854; GO:0046935; GO:0060396; GO:0060749 24339 FUN_038531 4622 4767 1851 4510 5213 ptg000027l:8437869-8441442 P34897 8.33e-136 Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) Homo sapiens (Human) folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell population proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; purine nucleobase biosynthetic process [GO:0009113]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial translation [GO:0070129]; regulation of oxidative phosphorylation [GO:0002082]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0000900; GO:0002082; GO:0003682; GO:0004372; GO:0005634; GO:0005737; GO:0005739; GO:0005743; GO:0005758; GO:0005759; GO:0005829; GO:0006544; GO:0006563; GO:0006564; GO:0006565; GO:0006730; GO:0008270; GO:0008284; GO:0008732; GO:0009113; GO:0015630; GO:0019264; GO:0030170; GO:0034340; GO:0035999; GO:0042645; GO:0042803; GO:0046653; GO:0046655; GO:0048027; GO:0051262; GO:0051289; GO:0070062; GO:0070129; GO:0070536; GO:0070552; GO:0070905; GO:1903715 24340 FUN_038531 4622 4767 1851 4510 5213 ptg000027l:8437869-8441442 P34897 8.65e-24 Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) Homo sapiens (Human) folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell population proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; purine nucleobase biosynthetic process [GO:0009113]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial translation [GO:0070129]; regulation of oxidative phosphorylation [GO:0002082]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0000900; GO:0002082; GO:0003682; GO:0004372; GO:0005634; GO:0005737; GO:0005739; GO:0005743; GO:0005758; GO:0005759; GO:0005829; GO:0006544; GO:0006563; GO:0006564; GO:0006565; GO:0006730; GO:0008270; GO:0008284; GO:0008732; GO:0009113; GO:0015630; GO:0019264; GO:0030170; GO:0034340; GO:0035999; GO:0042645; GO:0042803; GO:0046653; GO:0046655; GO:0048027; GO:0051262; GO:0051289; GO:0070062; GO:0070129; GO:0070536; GO:0070552; GO:0070905; GO:1903715 24341 FUN_038531 4622 4767 1851 4510 5213 ptg000027l:8437869-8441442 P34897 1.95e-21 Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase) Homo sapiens (Human) folic acid metabolic process [GO:0046655]; glycine biosynthetic process from serine [GO:0019264]; glycine metabolic process [GO:0006544]; L-serine biosynthetic process [GO:0006564]; L-serine catabolic process [GO:0006565]; L-serine metabolic process [GO:0006563]; one-carbon metabolic process [GO:0006730]; positive regulation of cell population proliferation [GO:0008284]; protein homotetramerization [GO:0051289]; protein K63-linked deubiquitination [GO:0070536]; protein tetramerization [GO:0051262]; purine nucleobase biosynthetic process [GO:0009113]; regulation of aerobic respiration [GO:1903715]; regulation of mitochondrial translation [GO:0070129]; regulation of oxidative phosphorylation [GO:0002082]; response to type I interferon [GO:0034340]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0000900; GO:0002082; GO:0003682; GO:0004372; GO:0005634; GO:0005737; GO:0005739; GO:0005743; GO:0005758; GO:0005759; GO:0005829; GO:0006544; GO:0006563; GO:0006564; GO:0006565; GO:0006730; GO:0008270; GO:0008284; GO:0008732; GO:0009113; GO:0015630; GO:0019264; GO:0030170; GO:0034340; GO:0035999; GO:0042645; GO:0042803; GO:0046653; GO:0046655; GO:0048027; GO:0051262; GO:0051289; GO:0070062; GO:0070129; GO:0070536; GO:0070552; GO:0070905; GO:1903715 24342 FUN_038530 0 0 26 28 0 NA NA NA NA NA NA NA 24343 FUN_038536 13 139 0 6 141 NA NA NA NA NA NA NA 24344 FUN_038535 417 242 252 199 234 ptg000027l:8469301-8474883 Q9JIA7 2.08e-21 Sphingosine kinase 2 (SK 2) (SPK 2) (EC 2.7.1.91) Mus musculus (Mouse) blood vessel development [GO:0001568]; brain development [GO:0007420]; cell population proliferation [GO:0008283]; cellular response to phorbol 13-acetate 12-myristate [GO:1904628]; female pregnancy [GO:0007565]; histone H2A-K5 acetylation [GO:0043977]; histone H2B-K12 acetylation [GO:0043980]; negative regulation of cell growth [GO:0030308]; negative regulation of histone deacetylase activity [GO:1901726]; negative regulation of histone deacetylation [GO:0031064]; phosphorylation [GO:0016310]; positive regulation of apoptotic process [GO:0043065]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of histone H3-K9 acetylation [GO:2000617]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of mast cell activation involved in immune response [GO:0033008]; positive regulation of mast cell degranulation [GO:0043306]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of ATP biosynthetic process [GO:2001169]; regulation of cytochrome-c oxidase activity [GO:1904959]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; sphinganine-1-phosphate biosynthetic process [GO:0006669]; sphingolipid metabolic process [GO:0006665]; sphingosine biosynthetic process [GO:0046512]; sphingosine metabolic process [GO:0006670]; transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000786; GO:0001568; GO:0001727; GO:0002720; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005743; GO:0005765; GO:0005783; GO:0005829; GO:0005886; GO:0006665; GO:0006669; GO:0006670; GO:0007420; GO:0007565; GO:0008283; GO:0008284; GO:0008481; GO:0016020; GO:0016310; GO:0017050; GO:0030308; GO:0031064; GO:0032736; GO:0032755; GO:0032760; GO:0033008; GO:0038036; GO:0042393; GO:0043065; GO:0043122; GO:0043231; GO:0043306; GO:0043977; GO:0043980; GO:0045815; GO:0046512; GO:0090037; GO:0090280; GO:1901726; GO:1903426; GO:1904628; GO:1904959; GO:2000304; GO:2000617; GO:2001169 24345 FUN_038534 5396 2121 2475 3280 2420 ptg000027l:8461433-8462599 Q5R1W5 1.36e-41 Serine/arginine-rich splicing factor 2 (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2) Pan troglodytes (Chimpanzee) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0016607 24346 FUN_024557 3625 1878 1104 2136 1683 NA NA NA NA NA NA NA 24347 FUN_023939 0 26 20 1 1 NA NA NA NA NA NA NA 24348 FUN_023938 1316 1787 264 707 492 NA NA NA NA NA NA NA 24349 FUN_023937 1716 2433 911 1540 1754 ptg000018l:325593-334036 Q7SG06 6.54e-21 Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) protein folding [GO:0006457]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005634; GO:0005737; GO:0006457; GO:0016018; GO:0043231 24350 FUN_023936 957 1638 1435 955 604 NA NA NA NA NA NA NA 24351 FUN_023935 1074 964 1575 894 936 NA NA NA NA NA NA NA 24352 FUN_023934 9162 9709 2775 7341 5551 NA NA NA NA NA NA NA 24353 FUN_023933 1284 1029 703 1066 851 NA NA NA NA NA NA NA 24354 FUN_023932 3467 1492 1669 2400 3205 NA NA NA NA NA NA NA 24355 FUN_023931 1192 1353 1106 1301 860 ptg000018l:280151-283110 Q5TNH5 8.23e-45 Glucosamine-6-phosphate isomerase (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase) (GNPDA) (GlcN6P deaminase) Anopheles gambiae (African malaria mosquito) carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262] GO:0004342; GO:0005737; GO:0005975; GO:0006043; GO:0006046; GO:0006091; GO:0019262; GO:0042802 24356 FUN_023931 1192 1353 1106 1301 860 ptg000018l:280151-283110 Q5TNH5 1.07e-24 Glucosamine-6-phosphate isomerase (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase) (GNPDA) (GlcN6P deaminase) Anopheles gambiae (African malaria mosquito) carbohydrate metabolic process [GO:0005975]; generation of precursor metabolites and energy [GO:0006091]; glucosamine catabolic process [GO:0006043]; N-acetylglucosamine catabolic process [GO:0006046]; N-acetylneuraminate catabolic process [GO:0019262] GO:0004342; GO:0005737; GO:0005975; GO:0006043; GO:0006046; GO:0006091; GO:0019262; GO:0042802 24357 FUN_023930 56 69 41 44 165 ptg000018l:263326-269106 O54853 1.25e-29 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 24358 FUN_023930 56 69 41 44 165 ptg000018l:263326-269106 O54853 1.64e-28 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 24359 FUN_024552 19 27 0 0 16 NA NA NA NA NA NA NA 24360 FUN_008102 0 17 0 19 28 NA NA NA NA NA NA NA 24361 FUN_024558 1500 1530 1043 1159 872 NA NA NA NA NA NA NA 24362 FUN_008108 1307 979 955 1785 2166 NA NA NA NA NA NA NA 24363 FUN_015808 72 0 0 0 61 NA NA NA NA NA NA NA 24364 FUN_015806 68 0 0 87 0 NA NA NA NA NA NA NA 24365 FUN_040038 3314 2532 1478 2594 2041 NA NA NA NA NA NA NA 24366 FUN_029453 1998 900 810 1915 1292 NA NA NA NA NA NA NA 24367 FUN_022389 1066 723 617 1111 1554 ptg000016l:8501864-8545488 Q96M86 1.07e-30 Dynein heavy chain domain-containing protein 1 (Coiled-coil domain-containing protein 35) (Dynein heavy chain domain 1-like protein) Homo sapiens (Human) cilium movement [GO:0003341]; flagellated sperm motility [GO:0030317]; microtubule-based movement [GO:0007018]; sperm flagellum assembly [GO:0120316] GO:0003341; GO:0005524; GO:0007018; GO:0008569; GO:0030286; GO:0030317; GO:0036126; GO:0036156; GO:0045505; GO:0051959; GO:0070062; GO:0120316 24368 FUN_022388 669 352 522 783 405 NA NA NA NA NA NA NA 24369 FUN_027139 194 1173 154 689 359 NA NA NA NA NA NA NA 24370 FUN_027138 2 0 0 7 0 NA NA NA NA NA NA NA 24371 FUN_027133 2357 2094 1260 2967 1480 NA NA NA NA NA NA NA 24372 FUN_027132 0 284 0 201 33 NA NA NA NA NA NA NA 24373 FUN_027131 15 8 0 0 0 NA NA NA NA NA NA NA 24374 FUN_027130 1239 1463 729 1415 906 NA NA NA NA NA NA NA 24375 FUN_027137 543 1692 563 1389 1180 NA NA NA NA NA NA NA 24376 FUN_027136 736 3298 1079 1852 1601 NA NA NA NA NA NA NA 24377 FUN_027135 174 1192 475 756 381 NA NA NA NA NA NA NA 24378 FUN_027134 452 2021 596 1378 1192 NA NA NA NA NA NA NA 24379 FUN_022383 1324 1377 934 1239 861 NA NA NA NA NA NA NA 24380 FUN_022382 11 0 21 21 0 NA NA NA NA NA NA NA 24381 FUN_022386 904 347 592 1995 590 ptg000016l:8417890-8465831 P00765 2.51e-23 Trypsin-1 (EC 3.4.21.4) (Trypsin I) Astacus astacus (Noble crayfish) (Astacus fluviatilis) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872 24382 FUN_022386 904 347 592 1995 590 ptg000016l:8417890-8465831 P00765 3.19e-23 Trypsin-1 (EC 3.4.21.4) (Trypsin I) Astacus astacus (Noble crayfish) (Astacus fluviatilis) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872 24383 FUN_022386 904 347 592 1995 590 ptg000016l:8417890-8465831 P00765 3.44e-23 Trypsin-1 (EC 3.4.21.4) (Trypsin I) Astacus astacus (Noble crayfish) (Astacus fluviatilis) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872 24384 FUN_010054 15 19 0 0 14 NA NA NA NA NA NA NA 24385 FUN_010055 0 0 0 2 32 NA NA NA NA NA NA NA 24386 FUN_034996 759 338 566 909 804 NA NA NA NA NA NA NA 24387 FUN_036737 14 0 4 0 25 NA NA NA NA NA NA NA 24388 FUN_036736 0 0 0 0 44 NA NA NA NA NA NA NA 24389 FUN_027742 6 0 0 0 0 NA NA NA NA NA NA NA 24390 FUN_023258 1620 1543 1589 1362 818 NA NA NA NA NA NA NA 24391 FUN_023259 5835 8341 1610 5872 2877 NA NA NA NA NA NA NA 24392 FUN_023252 3572 2437 1974 1946 1894 NA NA NA NA NA NA NA 24393 FUN_023253 10 4 4 10 13 NA NA NA NA NA NA NA 24394 FUN_023250 3832 3058 2249 3280 5089 ptg000017l:5524968-5535466 Q9GR88 1.44e-24 Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) Polyandrocarpa misakiensis (Tunicate) NA GO:0003747; GO:0005737 24395 FUN_023250 3832 3058 2249 3280 5089 ptg000017l:5524968-5535466 Q9GR88 1.44e-24 Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) Polyandrocarpa misakiensis (Tunicate) NA GO:0003747; GO:0005737 24396 FUN_023250 3832 3058 2249 3280 5089 ptg000017l:5524968-5535466 Q9GR88 6.52e-21 Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) Polyandrocarpa misakiensis (Tunicate) NA GO:0003747; GO:0005737 24397 FUN_023251 5142 2719 2554 4268 3735 NA NA NA NA NA NA NA 24398 FUN_023256 910 511 507 835 689 NA NA NA NA NA NA NA 24399 FUN_023257 1234 688 514 925 1085 NA NA NA NA NA NA NA 24400 FUN_023254 12 15 12 42 21 ptg000017l:5582749-5583781 Q924H0 9.84e-31 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 24401 FUN_023255 273 422 210 211 205 NA NA NA NA NA NA NA 24402 FUN_004277 1839 1226 861 1932 1592 NA NA NA NA NA NA NA 24403 FUN_004276 985 1359 1293 995 1102 NA NA NA NA NA NA NA 24404 FUN_004275 1456 1085 735 1260 757 NA NA NA NA NA NA NA 24405 FUN_004274 415 384 50 183 135 NA NA NA NA NA NA NA 24406 FUN_004273 677 738 436 755 305 NA NA NA NA NA NA NA 24407 FUN_004272 446 412 256 348 412 NA NA NA NA NA NA NA 24408 FUN_004271 80 127 46 36 28 NA NA NA NA NA NA NA 24409 FUN_004270 3154 2677 1350 2323 1983 ntLink_8:21410696-21416488 O35459 2.27e-26 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0005739; GO:0005777; GO:0006635; GO:0051750 24410 FUN_004270 3154 2677 1350 2323 1983 ntLink_8:21410696-21416488 O35459 2.27e-26 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (EC 5.3.3.-) Mus musculus (Mouse) fatty acid beta-oxidation [GO:0006635] GO:0005739; GO:0005777; GO:0006635; GO:0051750 24411 FUN_004279 193 57 55 371 276 ntLink_8:21479301-21482809 Q9UJA9 4.35e-31 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 24412 FUN_004279 193 57 55 371 276 ntLink_8:21479301-21482809 Q9UJA9 4e-25 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 24413 FUN_004278 62 103 68 46 33 NA NA NA NA NA NA NA 24414 FUN_024373 959 860 354 592 504 ptg000018l:5518935-5529647 Q6ZNB6 7.91e-22 NF-X1-type zinc finger protein NFXL1 (Ovarian zinc finger protein) (hOZFP) Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000785; GO:0000977; GO:0000981; GO:0005634; GO:0006355; GO:0008270; GO:0016020 24415 FUN_031539 5 0 0 50 0 NA NA NA NA NA NA NA 24416 FUN_033948 29539 9316 8144 15173 12699 NA NA NA NA NA NA NA 24417 FUN_033943 2991 1372 799 1541 1846 NA NA NA NA NA NA NA 24418 FUN_033942 306 28 67 156 250 ptg000024l:2940923-2965231 P25291 6.39e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 24419 FUN_033942 306 28 67 156 250 ptg000024l:2940923-2965231 P25291 7.71e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 24420 FUN_033942 306 28 67 156 250 ptg000024l:2940923-2965231 P25291 7.71e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 24421 FUN_033942 306 28 67 156 250 ptg000024l:2940923-2965231 P25291 7.71e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 24422 FUN_033942 306 28 67 156 250 ptg000024l:2940923-2965231 P25291 7.71e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 24423 FUN_033942 306 28 67 156 250 ptg000024l:2940923-2965231 P25291 1.69e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 24424 FUN_033941 477 127 142 340 259 NA NA NA NA NA NA NA 24425 FUN_033940 21 5 0 53 12 ptg000024l:2916103-2919745 Q4R1I4 1.5e-28 Melanopsin (Opsin-4) (amphi-MOP) Branchiostoma belcheri (Amphioxus) G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0005886; GO:0007186; GO:0007601; GO:0007602; GO:0008020; GO:0016020 24426 FUN_033947 2250 2204 2748 2514 1463 NA NA NA NA NA NA NA 24427 FUN_033946 49 0 18 89 210 NA NA NA NA NA NA NA 24428 FUN_033945 163 147 168 132 78 NA NA NA NA NA NA NA 24429 FUN_033944 533 257 207 315 534 ptg000024l:2987184-2992265 Q96FG2 4.03e-27 ELMO domain-containing protein 3 (RNA-binding motif and ELMO domain-containing protein 1) (RNA-binding motif protein 29) (RNA-binding protein 29) Homo sapiens (Human) NA GO:0005737; GO:0005856; GO:0005886; GO:0032420; GO:0060091 24430 FUN_018849 7 2 0 0 103 NA NA NA NA NA NA NA 24431 FUN_018848 63 44 68 60 79 ptg000012l:14262111-14356433 P21328 5.43e-38 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 24432 FUN_018848 63 44 68 60 79 ptg000012l:14262111-14356433 P21328 3.55e-23 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 24433 FUN_018841 0 0 0 0 18 NA NA NA NA NA NA NA 24434 FUN_018842 4228 3481 2535 3995 3893 NA NA NA NA NA NA NA 24435 FUN_018847 88 0 75 171 34 ptg000012l:14238753-14246068 P04323 5.77e-32 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24436 FUN_018847 88 0 75 171 34 ptg000012l:14238753-14246068 P04323 5.77e-32 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24437 FUN_018846 0 3 4 21 125 NA NA NA NA NA NA NA 24438 FUN_008236 1267 858 535 825 520 NA NA NA NA NA NA NA 24439 FUN_024379 110 126 148 151 97 NA NA NA NA NA NA NA 24440 FUN_031632 78 191 166 766 223 NA NA NA NA NA NA NA 24441 FUN_038637 241 176 103 318 193 NA NA NA NA NA NA NA 24442 FUN_008234 1432 980 440 855 695 NA NA NA NA NA NA NA 24443 FUN_018190 534 532 330 998 783 NA NA NA NA NA NA NA 24444 FUN_007818 227 110 176 151 151 ptg000002l:5046738-5058311 Q9YGL3 3.2e-24 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 24445 FUN_007819 533 297 261 292 530 NA NA NA NA NA NA NA 24446 FUN_035453 709 801 386 1300 892 ptg000025l:7589834-7594953 F4KGU4 0 ATP-dependent RNA helicase DEAH12, chloroplastic (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) NA GO:0003723; GO:0003724; GO:0005524; GO:0009507; GO:0016740; GO:0016887; GO:0046872; GO:0140096 24447 FUN_035452 4775 2781 2306 4197 2680 NA NA NA NA NA NA NA 24448 FUN_035451 223 380 458 398 460 ptg000025l:7554013-7554845 A2BGU9 9.65e-36 Serine hydrolase-like protein (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016787 24449 FUN_035450 148 35 89 79 8 ptg000025l:7551574-7553182 A2BGU9 1.71e-33 Serine hydrolase-like protein (EC 3.1.-.-) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016787 24450 FUN_035457 387 419 239 557 387 NA NA NA NA NA NA NA 24451 FUN_035456 1235 828 672 1892 1505 ptg000025l:7608219-7613190 F4KGU4 0 ATP-dependent RNA helicase DEAH12, chloroplastic (EC 3.6.4.13) Arabidopsis thaliana (Mouse-ear cress) NA GO:0003723; GO:0003724; GO:0005524; GO:0009507; GO:0016740; GO:0016887; GO:0046872; GO:0140096 24452 FUN_035455 25 23 46 35 35 NA NA NA NA NA NA NA 24453 FUN_007817 0 6 0 0 2 NA NA NA NA NA NA NA 24454 FUN_035459 574 493 262 533 196 NA NA NA NA NA NA NA 24455 FUN_035458 983 790 519 1180 499 NA NA NA NA NA NA NA 24456 FUN_018199 92 0 17 97 88 NA NA NA NA NA NA NA 24457 FUN_004912 155 199 109 174 126 NA NA NA NA NA NA NA 24458 FUN_012036 45 3888 1825 8178 8376 ptg000008l:4313751-4332601 Q8IVG5 5.15e-89 Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like) Homo sapiens (Human) NA GO:0005737; GO:0005739; GO:0005769 24459 FUN_004910 484 136 146 136 190 NA NA NA NA NA NA NA 24460 FUN_004916 1813 1337 601 1393 741 NA NA NA NA NA NA NA 24461 FUN_004917 583 730 183 706 677 ntLink_8:28711452-28712199 Q9Y2Y9 1.54e-42 Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Novel Sp1-like zinc finger transcription factor 1) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3) (Transcription factor NSLP1) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; negative regulation of erythrocyte differentiation [GO:0045647]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription by RNA polymerase II [GO:0006366] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0006357; GO:0006366; GO:0008285; GO:0045647; GO:0046872; GO:1990837 24462 FUN_004914 168 172 109 41 117 NA NA NA NA NA NA NA 24463 FUN_004915 0 0 0 6 0 NA NA NA NA NA NA NA 24464 FUN_004918 443 394 277 262 313 ntLink_8:28720685-28724669 Q6GQQ9 1.96e-60 OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne) Homo sapiens (Human) adaptive immune response [GO:0002250]; in utero embryonic development [GO:0001701]; mucosal immune response [GO:0002385]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; negative regulation of protein localization to nucleus [GO:1900181]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K48-linked deubiquitination [GO:0071108]; protein K63-linked deubiquitination [GO:0070536] GO:0000122; GO:0001701; GO:0002250; GO:0002385; GO:0003677; GO:0004843; GO:0005634; GO:0005737; GO:0005829; GO:0008234; GO:0008270; GO:0016579; GO:0032717; GO:0035871; GO:0043124; GO:0070530; GO:0070536; GO:0071108; GO:0071947; GO:1900181; GO:1990380 24465 FUN_004919 2516 2476 1639 2739 1874 NA NA NA NA NA NA NA 24466 FUN_012034 114 171 93 158 134 NA NA NA NA NA NA NA 24467 FUN_007813 952 1356 766 1422 1350 ptg000002l:5023225-5027923 Q9Y6A2 1.26e-35 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 24468 FUN_007813 952 1356 766 1422 1350 ptg000002l:5023225-5027923 Q9Y6A2 4.86e-26 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 24469 FUN_031516 9751 4410 878 3369 278 NA NA NA NA NA NA NA 24470 FUN_031517 350 210 187 228 170 NA NA NA NA NA NA NA 24471 FUN_031514 25 78 6 26 18 NA NA NA NA NA NA NA 24472 FUN_012035 1268 1264 466 1645 1469 ptg000008l:4288165-4307644 P97329 4.73e-21 Kinesin-like protein KIF20A (Kinesin-like protein 174) (Rab6-interacting kinesin-like protein) (Rabkinesin-6) Mus musculus (Mouse) microtubule bundle formation [GO:0001578]; microtubule-based movement [GO:0007018]; midbody abscission [GO:0061952]; mitotic cytokinesis [GO:0000281]; protein transport [GO:0015031]; regulation of cytokinesis [GO:0032465] GO:0000281; GO:0001578; GO:0003777; GO:0005524; GO:0005634; GO:0005654; GO:0005794; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0015031; GO:0016887; GO:0019901; GO:0030496; GO:0032465; GO:0045171; GO:0061952 24473 FUN_031512 1305 568 611 1376 367 NA NA NA NA NA NA NA 24474 FUN_031513 2366 1300 846 1743 478 NA NA NA NA NA NA NA 24475 FUN_031510 510 507 463 556 574 NA NA NA NA NA NA NA 24476 FUN_031511 1109 690 277 845 1531 NA NA NA NA NA NA NA 24477 FUN_017000 125 36 11 125 16 ptg000011l:10065783-10066620 R1CW23 2.7e-101 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 24478 FUN_007811 36 38 20 25 0 ptg000002l:4992062-4999291 B8VIU6 3.64e-32 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24479 FUN_031518 837 404 426 700 584 NA NA NA NA NA NA NA 24480 FUN_017003 929 0 12 27 135 NA NA NA NA NA NA NA 24481 FUN_001989 6 14 27 2303 1335 NA NA NA NA NA NA NA 24482 FUN_001982 0 0 8 0 0 NA NA NA NA NA NA NA 24483 FUN_001983 17 0 21 9 296 NA NA NA NA NA NA NA 24484 FUN_001984 6 0 7 3 104 NA NA NA NA NA NA NA 24485 FUN_032157 293 379 286 577 150 NA NA NA NA NA NA NA 24486 FUN_032156 5740 3443 3191 4127 2617 NA NA NA NA NA NA NA 24487 FUN_032155 4542 4928 3463 2369 2630 NA NA NA NA NA NA NA 24488 FUN_032154 2444 2236 1312 1304 2895 NA NA NA NA NA NA NA 24489 FUN_032153 1161 924 665 1115 1336 NA NA NA NA NA NA NA 24490 FUN_032151 26037 16493 12424 29516 9042 ptg000023l:29233914-29236764 P34960 1.82e-33 Macrophage metalloelastase (MME) (EC 3.4.24.65) (Matrix metalloproteinase-12) (MMP-12) Mus musculus (Mouse) bronchiole development [GO:0060435]; cellular response to virus [GO:0098586]; collagen catabolic process [GO:0030574]; elastin catabolic process [GO:0060309]; extracellular matrix organization [GO:0030198]; lung alveolus development [GO:0048286]; negative regulation of endothelial cell-matrix adhesion via fibronectin [GO:1904905]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of epithelial cell proliferation involved in wound healing [GO:0060054]; positive regulation of gene expression [GO:0010628]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; protein import into nucleus [GO:0006606]; proteolysis [GO:0006508]; regulation of defense response to virus by host [GO:0050691]; regulation of trophoblast cell migration [GO:1901163]; wound healing, spreading of epidermal cells [GO:0035313] GO:0000122; GO:0001046; GO:0004222; GO:0005509; GO:0005518; GO:0005576; GO:0005615; GO:0005634; GO:0005737; GO:0006508; GO:0006606; GO:0008270; GO:0010628; GO:0030198; GO:0030574; GO:0031012; GO:0032727; GO:0035313; GO:0043565; GO:0045944; GO:0048286; GO:0050691; GO:0060054; GO:0060309; GO:0060339; GO:0060340; GO:0060435; GO:0098586; GO:1901163; GO:1904905 24491 FUN_032150 1906 2821 6838 8838 5375 NA NA NA NA NA NA NA 24492 FUN_032159 256 202 289 265 140 NA NA NA NA NA NA NA 24493 FUN_032158 253 365 207 402 167 ptg000023l:29281236-29291607 Q8NCM2 2.38e-34 Potassium voltage-gated channel subfamily H member 5 (Ether-a-go-go potassium channel 2) (hEAG2) (Voltage-gated potassium channel subunit Kv10.2) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005516; GO:0005886; GO:0009986; GO:0010389; GO:0034765; GO:0042391; GO:0044325; GO:0044877; GO:0071805 24494 FUN_043940 3 4 8 2 54 NA NA NA NA NA NA NA 24495 FUN_043941 78 155 150 155 350 NA NA NA NA NA NA NA 24496 FUN_000163 2 0 5 0 12 ntLink_4:268290-269053 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24497 FUN_000161 3 0 7 0 13 ntLink_4:264224-264987 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24498 FUN_000167 2 1 4 0 15 ntLink_4:276422-277185 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24499 FUN_000165 1 1 4 0 18 ntLink_4:272356-273119 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24500 FUN_015102 805 428 197 380 572 NA NA NA NA NA NA NA 24501 FUN_007755 621 488 468 562 496 NA NA NA NA NA NA NA 24502 FUN_007754 777 385 271 596 339 NA NA NA NA NA NA NA 24503 FUN_007757 359 366 358 426 225 NA NA NA NA NA NA NA 24504 FUN_007756 34 73 18 9 18 NA NA NA NA NA NA NA 24505 FUN_007751 722 704 212 187 129 NA NA NA NA NA NA NA 24506 FUN_007750 168 267 86 167 100 NA NA NA NA NA NA NA 24507 FUN_007753 17 9 27 129 91 NA NA NA NA NA NA NA 24508 FUN_007752 39 16 3 35 26 NA NA NA NA NA NA NA 24509 FUN_007759 5243 2880 3210 3391 3703 NA NA NA NA NA NA NA 24510 FUN_007758 3806 3165 1805 3532 1884 NA NA NA NA NA NA NA 24511 FUN_038631 109 116 14 35 44 NA NA NA NA NA NA NA 24512 FUN_000299 91 13 69 132 93 NA NA NA NA NA NA NA 24513 FUN_000298 38 4 72 0 33 NA NA NA NA NA NA NA 24514 FUN_005669 0 0 2 0 10 NA NA NA NA NA NA NA 24515 FUN_000295 618 351 504 999 728 NA NA NA NA NA NA NA 24516 FUN_005666 0 0 3 0 9 NA NA NA NA NA NA NA 24517 FUN_000297 177 75 27 86 180 NA NA NA NA NA NA NA 24518 FUN_000296 401 232 254 710 567 NA NA NA NA NA NA NA 24519 FUN_000291 242 142 193 121 27 NA NA NA NA NA NA NA 24520 FUN_000290 272 99 92 186 25 NA NA NA NA NA NA NA 24521 FUN_005661 0 0 2 0 6 NA NA NA NA NA NA NA 24522 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 2.38e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24523 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 2.81e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24524 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 4.4e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24525 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 7.64e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24526 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 4.8e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24527 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 3.93e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24528 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 2.19e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24529 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 1.47e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24530 FUN_033205 65 0 27 30 10 ptg000023l:41098540-41100164 Q96AY4 3.01e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24531 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24532 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 1.45e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24533 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 8.39e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24534 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 1.32e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24535 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 6.32e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24536 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 3.94e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24537 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 2.31e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24538 FUN_033207 1 17 0 13 2 ptg000023l:41121781-41126112 Q96AY4 2.31e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24539 FUN_033200 49 8 2 47 35 ptg000023l:41011448-41016053 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24540 FUN_033200 49 8 2 47 35 ptg000023l:41011448-41016053 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24541 FUN_033200 49 8 2 47 35 ptg000023l:41011448-41016053 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24542 FUN_033200 49 8 2 47 35 ptg000023l:41011448-41016053 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24543 FUN_033200 49 8 2 47 35 ptg000023l:41011448-41016053 Q96AY4 1.98e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24544 FUN_033200 49 8 2 47 35 ptg000023l:41011448-41016053 Q96AY4 1.73e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24545 FUN_033201 0 11 1 7 4 ptg000023l:41028665-41034577 Q96AY4 2.42e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24546 FUN_033201 0 11 1 7 4 ptg000023l:41028665-41034577 Q96AY4 5.55e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24547 FUN_033201 0 11 1 7 4 ptg000023l:41028665-41034577 Q96AY4 7.86e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24548 FUN_033201 0 11 1 7 4 ptg000023l:41028665-41034577 Q96AY4 1.05e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24549 FUN_033201 0 11 1 7 4 ptg000023l:41028665-41034577 Q96AY4 4.1e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24550 FUN_033201 0 11 1 7 4 ptg000023l:41028665-41034577 Q96AY4 2.46e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24551 FUN_033202 122 81 56 60 72 NA NA NA NA NA NA NA 24552 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24553 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24554 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24555 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 1.57e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24556 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 4.14e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24557 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 6.87e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24558 FUN_033203 48 32 7 81 117 ptg000023l:41062106-41068754 Q96AY4 1.89e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24559 FUN_033209 5 28 0 12 0 ptg000023l:41136239-41140520 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24560 FUN_033209 5 28 0 12 0 ptg000023l:41136239-41140520 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24561 FUN_033209 5 28 0 12 0 ptg000023l:41136239-41140520 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24562 FUN_033209 5 28 0 12 0 ptg000023l:41136239-41140520 Q96AY4 2e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24563 FUN_033209 5 28 0 12 0 ptg000023l:41136239-41140520 Q96AY4 1.39e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24564 FUN_006845 284 206 267 223 176 ptg000001l:17307929-17310917 Q8AWB5 3.92e-99 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Gallus gallus (Chicken) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0046920 24565 FUN_016910 0 0 0 63 0 NA NA NA NA NA NA NA 24566 FUN_016913 0 0 0 19 0 NA NA NA NA NA NA NA 24567 FUN_016912 0 0 0 25 0 NA NA NA NA NA NA NA 24568 FUN_016915 81 32 34 873 216 NA NA NA NA NA NA NA 24569 FUN_016914 13 0 0 193 51 NA NA NA NA NA NA NA 24570 FUN_016917 70 21 41 0 183 NA NA NA NA NA NA NA 24571 FUN_016916 48 0 14 653 165 NA NA NA NA NA NA NA 24572 FUN_016919 20 12 13 54 0 NA NA NA NA NA NA NA 24573 FUN_016918 123 51 67 692 224 NA NA NA NA NA NA NA 24574 FUN_014786 899 787 509 606 757 NA NA NA NA NA NA NA 24575 FUN_018445 137 187 105 113 53 NA NA NA NA NA NA NA 24576 FUN_018444 180 57 82 51 8 NA NA NA NA NA NA NA 24577 FUN_018447 53 100 83 157 110 NA NA NA NA NA NA NA 24578 FUN_025257 430 587 436 239 280 ptg000019l:482434-484813 A3KPP4 1.36e-59 Solute carrier family 25 member 35 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005743 24579 FUN_025257 430 587 436 239 280 ptg000019l:482434-484813 A3KPP4 1.27e-38 Solute carrier family 25 member 35 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005743 24580 FUN_006408 3047 1855 713 2066 1118 NA NA NA NA NA NA NA 24581 FUN_006409 2691 1797 2051 3785 1855 NA NA NA NA NA NA NA 24582 FUN_006402 15 0 6 16 21 NA NA NA NA NA NA NA 24583 FUN_006403 7 2 19 0 123 NA NA NA NA NA NA NA 24584 FUN_006400 6 9 7 6 14 NA NA NA NA NA NA NA 24585 FUN_006406 0 8 0 12 0 NA NA NA NA NA NA NA 24586 FUN_006407 13 15 51 41 207 NA NA NA NA NA NA NA 24587 FUN_006404 0 0 0 0 38 NA NA NA NA NA NA NA 24588 FUN_018443 3133 875 690 1426 1275 NA NA NA NA NA NA NA 24589 FUN_034013 395 521 122 418 144 NA NA NA NA NA NA NA 24590 FUN_004138 190 77 30 51 50 NA NA NA NA NA NA NA 24591 FUN_004139 88 80 24 89 24 NA NA NA NA NA NA NA 24592 FUN_040378 0 0 0 0 18 NA NA NA NA NA NA NA 24593 FUN_040376 0 0 0 0 69 ptg000031l:7586793-7588099 Q5DU56 3.93e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 24594 FUN_040376 0 0 0 0 69 ptg000031l:7586793-7588099 Q5DU56 3.93e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 24595 FUN_010454 34 24 12 24 6 NA NA NA NA NA NA NA 24596 FUN_010455 410 12 4 36 17 NA NA NA NA NA NA NA 24597 FUN_004130 0 28 0 22 17 NA NA NA NA NA NA NA 24598 FUN_004131 5938 6838 4334 8665 2153 NA NA NA NA NA NA NA 24599 FUN_010450 542 37 25 522 33 NA NA NA NA NA NA NA 24600 FUN_004133 37 0 30 53 57 NA NA NA NA NA NA NA 24601 FUN_035750 1041 842 864 1046 958 NA NA NA NA NA NA NA 24602 FUN_034018 671 261 358 296 352 ptg000024l:3734398-3755844 Q9Z2E3 2.52e-52 Serine/threonine-protein kinase/endoribonuclease IRE2 (Endoplasmic reticulum-to-nucleus signaling 2) (Inositol-requiring protein 2) (Ire1-beta) (IRE1b) (mIre1) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)] Mus musculus (Mouse) apoptotic chromosome condensation [GO:0030263]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; IRE1-mediated unfolded protein response [GO:0036498]; mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; regulation of DNA-templated transcription [GO:0006355]; response to endoplasmic reticulum stress [GO:0034976]; rRNA catabolic process [GO:0016075] GO:0000287; GO:0004519; GO:0004521; GO:0004674; GO:0005524; GO:0005783; GO:0005829; GO:0006355; GO:0006397; GO:0006468; GO:0016075; GO:0030263; GO:0034976; GO:0036498; GO:0043507; GO:0044322; GO:0045892; GO:0051082; GO:0070059; GO:0106310; GO:1990604 24603 FUN_018448 0 96 13 84 140 NA NA NA NA NA NA NA 24604 FUN_026330 21 0 2 0 0 NA NA NA NA NA NA NA 24605 FUN_029907 14 2 9 3 38 NA NA NA NA NA NA NA 24606 FUN_034268 61 66 29 39 24 NA NA NA NA NA NA NA 24607 FUN_034267 50 124 23 60 36 NA NA NA NA NA NA NA 24608 FUN_034266 881 659 411 906 997 NA NA NA NA NA NA NA 24609 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 4.34e-146 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24610 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 5.9e-146 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24611 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 4.63e-51 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24612 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 2.49e-40 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24613 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 2.88e-40 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24614 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 7.25e-40 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24615 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 1.84e-29 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24616 FUN_034265 19127 12289 6779 14786 11915 ptg000024l:6824111-6829122 O15992 1.35e-27 Arginine kinase (AK) (EC 2.7.3.3) Anthopleura japonica (Sea anemone) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004054; GO:0004111; GO:0005524; GO:0016310; GO:0046314 24617 FUN_034264 1648 4157 1598 1939 909 NA NA NA NA NA NA NA 24618 FUN_034263 1079 1000 645 1506 1123 NA NA NA NA NA NA NA 24619 FUN_034262 714 624 579 1591 1173 NA NA NA NA NA NA NA 24620 FUN_034261 136 162 150 367 371 NA NA NA NA NA NA NA 24621 FUN_034260 3842 2594 2389 5345 3238 ptg000024l:6755812-6774933 Q9WUM7 6.03e-98 Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Mx-interacting protein kinase) (PKM) Mesocricetus auratus (Golden hamster) apoptotic process [GO:0006915]; cellular response to DNA damage stimulus [GO:0006974]; peptidyl-serine phosphorylation [GO:0018105] GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006915; GO:0006974; GO:0010494; GO:0016604; GO:0016605; GO:0018105; GO:0106310 24622 FUN_040998 134 191 0 165 280 NA NA NA NA NA NA NA 24623 FUN_040999 121 0 42 21 9 NA NA NA NA NA NA NA 24624 FUN_040992 65 120 43 63 91 ptg000033l:1084948-1087202 P83852 1.06e-87 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 24625 FUN_040993 16 63 11 16 30 NA NA NA NA NA NA NA 24626 FUN_040990 0 6 0 0 40 NA NA NA NA NA NA NA 24627 FUN_040996 0 0 0 0 14 NA NA NA NA NA NA NA 24628 FUN_040997 28 21 23 28 90 NA NA NA NA NA NA NA 24629 FUN_040994 2 0 8 10 0 NA NA NA NA NA NA NA 24630 FUN_023447 1001 409 391 137 278 NA NA NA NA NA NA NA 24631 FUN_028410 0 688 0 744 367 NA NA NA NA NA NA NA 24632 FUN_023445 155 163 0 39 36 NA NA NA NA NA NA NA 24633 FUN_002473 2391 1529 1167 2320 917 NA NA NA NA NA NA NA 24634 FUN_002472 454 301 238 364 281 NA NA NA NA NA NA NA 24635 FUN_002471 1193 644 685 1110 1102 ntLink_8:1940731-1980641 Q7Z6Z7 2.14e-37 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0043161; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:1903955; GO:1904813 24636 FUN_002471 1193 644 685 1110 1102 ntLink_8:1940731-1980641 Q7Z6Z7 2.46e-29 E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; cell differentiation [GO:0030154]; circadian regulation of gene expression [GO:0032922]; Golgi organization [GO:0007030]; histone ubiquitination [GO:0016574]; membrane fusion [GO:0061025]; negative regulation of mitochondrial fusion [GO:0010637]; positive regulation of mitophagy in response to mitochondrial depolarization [GO:0098779]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of protein ubiquitination [GO:0031398]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein monoubiquitination [GO:0006513]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000139; GO:0000209; GO:0003677; GO:0003723; GO:0004842; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0006284; GO:0006513; GO:0007030; GO:0010637; GO:0016020; GO:0016567; GO:0016574; GO:0030154; GO:0031398; GO:0032922; GO:0034774; GO:0043161; GO:0061025; GO:0061630; GO:0070062; GO:0098779; GO:1903955; GO:1904813 24637 FUN_002470 156 131 51 146 152 NA NA NA NA NA NA NA 24638 FUN_002477 971 19 1133 27 10 ntLink_8:2134062-2226228 P10394 1.65e-102 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24639 FUN_002476 829 439 1165 899 425 ntLink_8:2048781-2118943 P11369 2.86e-54 LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Mus musculus (Mouse) DNA recombination [GO:0006310] GO:0003964; GO:0004519; GO:0006310; GO:0046872 24640 FUN_002476 829 439 1165 899 425 ntLink_8:2048781-2118943 P11369 2.86e-54 LINE-1 retrotransposable element ORF2 protein (ORF2p) (Long interspersed element-1) (L1) (Retrovirus-related Pol polyprotein LINE-1) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Mus musculus (Mouse) DNA recombination [GO:0006310] GO:0003964; GO:0004519; GO:0006310; GO:0046872 24641 FUN_002475 433 116 206 178 191 NA NA NA NA NA NA NA 24642 FUN_002474 15 20 0 38 17 ntLink_8:2003223-2008894 Q80XJ3 3.58e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24643 FUN_002474 15 20 0 38 17 ntLink_8:2003223-2008894 Q80XJ3 1.57e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24644 FUN_002474 15 20 0 38 17 ntLink_8:2003223-2008894 Q80XJ3 2.89e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24645 FUN_002474 15 20 0 38 17 ntLink_8:2003223-2008894 Q80XJ3 3.2e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24646 FUN_002474 15 20 0 38 17 ntLink_8:2003223-2008894 Q80XJ3 3.83e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24647 FUN_002474 15 20 0 38 17 ntLink_8:2003223-2008894 Q80XJ3 5.95e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 24648 FUN_023443 1523 1078 1148 1682 749 NA NA NA NA NA NA NA 24649 FUN_002479 253 29 169 95 48 NA NA NA NA NA NA NA 24650 FUN_028414 0 0 1 55 0 NA NA NA NA NA NA NA 24651 FUN_012340 912 471 522 1252 857 NA NA NA NA NA NA NA 24652 FUN_012341 272 299 203 887 493 NA NA NA NA NA NA NA 24653 FUN_012342 1611 913 571 1163 1108 NA NA NA NA NA NA NA 24654 FUN_012343 513 201 146 828 394 NA NA NA NA NA NA NA 24655 FUN_012344 577 381 543 624 301 NA NA NA NA NA NA NA 24656 FUN_028417 80 0 68 95 1 NA NA NA NA NA NA NA 24657 FUN_012346 7774 7270 1930 3331 2515 NA NA NA NA NA NA NA 24658 FUN_012347 405 369 358 380 520 ptg000008l:8144808-8147780 Q9UGM6 1.32e-33 Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS) Homo sapiens (Human) mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; positive regulation of angiogenesis [GO:0045766]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570] GO:0001570; GO:0004830; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005886; GO:0006418; GO:0006436; GO:0045766; GO:0070183 24659 FUN_012347 405 369 358 380 520 ptg000008l:8144808-8147780 Q9UGM6 1.32e-33 Tryptophan--tRNA ligase, mitochondrial (EC 6.1.1.2) ((Mt)TrpRS) (Tryptophanyl-tRNA synthetase) (TrpRS) Homo sapiens (Human) mitochondrial tryptophanyl-tRNA aminoacylation [GO:0070183]; positive regulation of angiogenesis [GO:0045766]; tRNA aminoacylation for protein translation [GO:0006418]; tryptophanyl-tRNA aminoacylation [GO:0006436]; vasculogenesis [GO:0001570] GO:0001570; GO:0004830; GO:0005524; GO:0005654; GO:0005739; GO:0005759; GO:0005886; GO:0006418; GO:0006436; GO:0045766; GO:0070183 24660 FUN_012348 1801 1018 777 1325 847 NA NA NA NA NA NA NA 24661 FUN_012349 2614 1694 1070 2359 1983 ptg000008l:8163743-8172389 Q5XIK7 7.76e-42 Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 5.6.1.1) (p60 katanin-like 1) Rattus norvegicus (Rat) microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; spermatogenesis [GO:0007283] GO:0000226; GO:0000922; GO:0005524; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0007283; GO:0008017; GO:0008352; GO:0008568; GO:0015630; GO:0016853; GO:0016887; GO:0042802; GO:0051013 24662 FUN_035755 3631 2780 1966 3156 2040 NA NA NA NA NA NA NA 24663 FUN_028416 0 0 0 1112 0 ptg000021l:19606689-19655812 Q9NBX4 7.76e-23 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 24664 FUN_028416 0 0 0 1112 0 ptg000021l:19606689-19655812 Q9NBX4 7.76e-23 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 24665 FUN_028416 0 0 0 1112 0 ptg000021l:19606689-19655812 Q9NBX4 7.76e-23 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 24666 FUN_013431 21 3 6 0 20 NA NA NA NA NA NA NA 24667 FUN_014426 1 2 8 4 22 NA NA NA NA NA NA NA 24668 FUN_014425 6 7 96 33 321 NA NA NA NA NA NA NA 24669 FUN_014423 6 10 148 31 501 NA NA NA NA NA NA NA 24670 FUN_014421 0 0 9 0 4 NA NA NA NA NA NA NA 24671 FUN_013438 524 1374 133 430 104 ptg000008l:22453316-22528185 P14381 1.02e-105 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24672 FUN_014429 62 99 43 12 58 NA NA NA NA NA NA NA 24673 FUN_014428 0 4 112 0 4 NA NA NA NA NA NA NA 24674 FUN_003998 70 21 0 160 29 NA NA NA NA NA NA NA 24675 FUN_011494 62 0 0 0 161 NA NA NA NA NA NA NA 24676 FUN_011497 44 0 9 17 8 NA NA NA NA NA NA NA 24677 FUN_011496 51 0 6 12 32 NA NA NA NA NA NA NA 24678 FUN_000930 578 310 442 744 480 ntLink_6:6153327-6159051 A0LMC1 5.43e-54 Phosphonoacetaldehyde hydrolase (Phosphonatase) (EC 3.11.1.1) (Phosphonoacetaldehyde phosphonohydrolase) Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) organic phosphonate catabolic process [GO:0019700] GO:0000287; GO:0019700; GO:0050194 24679 FUN_000931 171 25 49 186 103 ntLink_6:6164973-6166455 Q6P4M0 1.56e-136 7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Sterol Delta(7)-reductase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cholesterol biosynthetic process [GO:0006695] GO:0005789; GO:0006695; GO:0047598; GO:0050661 24680 FUN_000932 3294 1604 1807 3210 2683 NA NA NA NA NA NA NA 24681 FUN_000933 2373 2264 1479 2864 2647 NA NA NA NA NA NA NA 24682 FUN_000934 1196 1865 499 1314 1296 NA NA NA NA NA NA NA 24683 FUN_000935 1792 2025 1160 1307 1741 ntLink_6:6234843-6241954 Q5ZL33 1.27e-21 Serine-threonine kinase receptor-associated protein Gallus gallus (Chicken) alternative mRNA splicing, via spliceosome [GO:0000380]; maintenance of gastrointestinal epithelium [GO:0030277]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; neuron differentiation [GO:0030182]; spliceosomal snRNP assembly [GO:0000387] GO:0000122; GO:0000380; GO:0000387; GO:0003729; GO:0004857; GO:0005102; GO:0005634; GO:0005829; GO:0030182; GO:0030277; GO:0030512; GO:0032797; GO:0034719; GO:0140416; GO:1990447 24684 FUN_029395 61 30 0 68 24 ptg000023l:1489090-1490883 P11009 2.39e-77 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 24685 FUN_029395 61 30 0 68 24 ptg000023l:1489090-1490883 P11009 6.62e-72 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 24686 FUN_029394 0 13 28 11 14 ptg000023l:1482679-1486567 P11009 4e-72 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 24687 FUN_029394 0 13 28 11 14 ptg000023l:1482679-1486567 P11009 3.65e-62 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 24688 FUN_029397 611 257 333 476 386 ptg000023l:1508913-1515737 Q5ZL00 2.8e-55 ER membrane protein complex subunit 1 Gallus gallus (Chicken) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005789; GO:0016020; GO:0045050; GO:0071816; GO:0072546 24689 FUN_029397 611 257 333 476 386 ptg000023l:1508913-1515737 Q5ZL00 2.89e-21 ER membrane protein complex subunit 1 Gallus gallus (Chicken) protein insertion into ER membrane by stop-transfer membrane-anchor sequence [GO:0045050]; tail-anchored membrane protein insertion into ER membrane [GO:0071816] GO:0005789; GO:0016020; GO:0045050; GO:0071816; GO:0072546 24690 FUN_029396 373 296 142 237 380 NA NA NA NA NA NA NA 24691 FUN_029393 354 230 372 833 582 NA NA NA NA NA NA NA 24692 FUN_029392 3378 3343 1928 3635 2778 NA NA NA NA NA NA NA 24693 FUN_043009 960 418 601 439 358 NA NA NA NA NA NA NA 24694 FUN_029399 102 38 0 0 204 NA NA NA NA NA NA NA 24695 FUN_029398 13 0 0 0 11 NA NA NA NA NA NA NA 24696 FUN_009740 0 7 4 38 0 NA NA NA NA NA NA NA 24697 FUN_009746 158 22 62 597 247 NA NA NA NA NA NA NA 24698 FUN_009747 296 19 15 22 0 NA NA NA NA NA NA NA 24699 FUN_009748 0 0 0 0 8 NA NA NA NA NA NA NA 24700 FUN_029649 5 0 0 0 32 NA NA NA NA NA NA NA 24701 FUN_029648 72 176 0 230 54 ptg000023l:4111069-4116590 F6QEU4 5.76e-41 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 24702 FUN_029646 17 101 21 123 116 ptg000023l:4104019-4107498 F6QEU4 6.15e-47 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 24703 FUN_029645 333 45 71 3 28 ptg000023l:4096900-4099099 E7FAM5 4.59e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 24704 FUN_029644 575 176 175 374 273 ptg000023l:4085965-4087456 Q92113 6.49e-144 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 24705 FUN_029643 50 7 0 0 0 NA NA NA NA NA NA NA 24706 FUN_029642 649 337 256 528 440 NA NA NA NA NA NA NA 24707 FUN_029641 30 69 92 50 153 NA NA NA NA NA NA NA 24708 FUN_029640 2412 2530 1642 1246 2418 ptg000023l:4021984-4038962 Q9QYP1 8.87e-30 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 24709 FUN_015775 241 46 159 278 276 NA NA NA NA NA NA NA 24710 FUN_015776 36 4 0 32 29 NA NA NA NA NA NA NA 24711 FUN_015777 138 27 116 249 174 NA NA NA NA NA NA NA 24712 FUN_015770 0 0 0 0 7 NA NA NA NA NA NA NA 24713 FUN_034600 633 867 245 1066 641 NA NA NA NA NA NA NA 24714 FUN_042266 748 605 800 723 1622 NA NA NA NA NA NA NA 24715 FUN_042267 0 15 8 16 83 NA NA NA NA NA NA NA 24716 FUN_042264 16 0 0 5 0 NA NA NA NA NA NA NA 24717 FUN_042262 11 0 6 5 15 NA NA NA NA NA NA NA 24718 FUN_042260 0 0 52 0 118 NA NA NA NA NA NA NA 24719 FUN_016141 1616 1005 595 1253 1281 NA NA NA NA NA NA NA 24720 FUN_023090 87 35 29 0 55 ptg000017l:3514193-3515132 C3ZQF9 3.68e-22 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 24721 FUN_023091 33 30 23 21 52 NA NA NA NA NA NA NA 24722 FUN_023092 0 3 9 22 42 ptg000017l:3546266-3547220 C3ZQF9 5.36e-23 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 24723 FUN_023093 177 2962 195 428 658 NA NA NA NA NA NA NA 24724 FUN_023094 202 4673 150 497 518 NA NA NA NA NA NA NA 24725 FUN_023095 10158 8077 4591 7584 4734 NA NA NA NA NA NA NA 24726 FUN_023096 193 470 205 70 447 ptg000017l:3587628-3591361 Q9H4G4 4.2e-39 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 24727 FUN_023096 193 470 205 70 447 ptg000017l:3587628-3591361 Q9H4G4 1.13e-23 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 24728 FUN_042269 36 27 14 6 45 NA NA NA NA NA NA NA 24729 FUN_015489 0 0 0 0 18 NA NA NA NA NA NA NA 24730 FUN_015486 1078 292 615 756 506 ptg000009l:10784004-10803389 O15439 7.34e-70 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 24731 FUN_015486 1078 292 615 756 506 ptg000009l:10784004-10803389 O15439 3.75e-52 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 24732 FUN_015486 1078 292 615 756 506 ptg000009l:10784004-10803389 O15439 7.89e-25 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 24733 FUN_015486 1078 292 615 756 506 ptg000009l:10784004-10803389 O15439 2.67e-23 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 24734 FUN_015487 245 94 26 261 29 ptg000009l:10816602-10830590 E9Q236 2.03e-65 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 24735 FUN_015487 245 94 26 261 29 ptg000009l:10816602-10830590 E9Q236 1.01e-51 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 24736 FUN_015487 245 94 26 261 29 ptg000009l:10816602-10830590 E9Q236 9.6e-27 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 24737 FUN_015487 245 94 26 261 29 ptg000009l:10816602-10830590 E9Q236 2.31e-25 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 24738 FUN_015484 91 531 2 189 0 NA NA NA NA NA NA NA 24739 FUN_015485 162 247 19 292 2 NA NA NA NA NA NA NA 24740 FUN_008831 9 29 0 4 7 NA NA NA NA NA NA NA 24741 FUN_008830 6 4 0 54 53 NA NA NA NA NA NA NA 24742 FUN_008835 0 0 0 24 0 NA NA NA NA NA NA NA 24743 FUN_008836 0 0 23 30 50 NA NA NA NA NA NA NA 24744 FUN_008839 0 0 12 11 100 NA NA NA NA NA NA NA 24745 FUN_000007 21 51 22 56 113 NA NA NA NA NA NA NA 24746 FUN_026570 1377 264 405 602 1130 NA NA NA NA NA NA NA 24747 FUN_026571 37 0 0 0 0 NA NA NA NA NA NA NA 24748 FUN_026572 414 108 201 241 549 NA NA NA NA NA NA NA 24749 FUN_026573 66 0 15 25 55 NA NA NA NA NA NA NA 24750 FUN_026574 4 0 5 0 42 NA NA NA NA NA NA NA 24751 FUN_026579 964 380 323 362 367 ptg000020l:10984903-10987231 Q5EB73 5.94e-31 Post-GPI attachment to proteins factor 4 (Post-GPI attachment to proteins GalNAc transferase 4) (Transmembrane protein 246) Rattus norvegicus (Rat) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0006506; GO:0016757 24752 FUN_028516 8 0 0 0 29 NA NA NA NA NA NA NA 24753 FUN_028517 12 0 4 4 15 NA NA NA NA NA NA NA 24754 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 7.54e-90 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24755 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 7.54e-90 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24756 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 7.54e-90 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24757 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 7.54e-90 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24758 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 7.54e-90 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24759 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 1.09e-25 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24760 FUN_028510 5977 2779 2720 3636 5105 ptg000021l:20834032-20839529 Q96RQ3 1.09e-25 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCase subunit alpha) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 1) (3-methylcrotonyl-CoA carboxylase biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha) Homo sapiens (Human) biotin metabolic process [GO:0006768]; branched-chain amino acid catabolic process [GO:0009083]; leucine catabolic process [GO:0006552] GO:0002169; GO:0004075; GO:0004485; GO:0005524; GO:0005739; GO:0005759; GO:0005829; GO:0006552; GO:0006768; GO:0009083; GO:0009374; GO:0046872; GO:1905202 24761 FUN_028511 3047 2565 2028 5743 6451 ptg000021l:20839733-20842877 Q9NFU0 2.41e-23 Fragile X messenger ribonucleoprotein 1 homolog (dFMR1) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; anterograde axonal transport [GO:0008089]; associative learning [GO:0008306]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cellularization [GO:0007349]; central nervous system development [GO:0007417]; circadian rhythm [GO:0007623]; circadian sleep/wake cycle, sleep [GO:0050802]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; germ cell development [GO:0007281]; germ-line cyst formation [GO:0048134]; germarium-derived oocyte fate determination [GO:0007294]; grooming behavior [GO:0007625]; habituation [GO:0046959]; heterochromatin formation [GO:0031507]; larval locomotory behavior [GO:0008345]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; medium-term memory [GO:0072375]; mitotic cell cycle, embryonic [GO:0045448]; mRNA transport [GO:0051028]; mushroom body development [GO:0016319]; negative regulation of axon extension [GO:0030517]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of synapse assembly [GO:0051964]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; negative regulation of translation [GO:0017148]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; neuron remodeling [GO:0016322]; olfactory behavior [GO:0042048]; olfactory learning [GO:0008355]; oocyte dorsal/ventral axis specification [GO:0007310]; pole cell formation [GO:0007279]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of programmed cell death [GO:0043068]; positive regulation of translation [GO:0045727]; post-embryonic digestive tract morphogenesis [GO:0048621]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell population proliferation [GO:0042127]; regulation of dendrite morphogenesis [GO:0048814]; regulation of dendritic spine development [GO:0060998]; regulation of mitotic cell cycle, embryonic [GO:0009794]; regulation of modification of synaptic structure [GO:1905244]; regulation of mRNA stability [GO:0043488]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of olfactory learning [GO:0090328]; regulation of synapse organization [GO:0050807]; regulation of synapse structural plasticity [GO:0051823]; regulation of translation [GO:0006417]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to odorant [GO:1990834]; RNA-mediated gene silencing [GO:0031047]; short-term memory [GO:0007614]; social behavior [GO:0035176]; sperm axoneme assembly [GO:0007288]; synapse organization [GO:0050808]; synapse pruning [GO:0098883]; synaptic vesicle budding [GO:0070142]; synaptic vesicle clustering [GO:0097091]; terminal button organization [GO:0072553]; visual perception [GO:0007601] GO:0000139; GO:0000900; GO:0002052; GO:0003723; GO:0003730; GO:0005634; GO:0005737; GO:0005844; GO:0006417; GO:0007279; GO:0007281; GO:0007288; GO:0007294; GO:0007310; GO:0007349; GO:0007409; GO:0007411; GO:0007413; GO:0007417; GO:0007420; GO:0007528; GO:0007601; GO:0007614; GO:0007616; GO:0007623; GO:0007625; GO:0008049; GO:0008089; GO:0008306; GO:0008344; GO:0008345; GO:0008355; GO:0009794; GO:0010494; GO:0010608; GO:0010629; GO:0014069; GO:0016020; GO:0016319; GO:0016322; GO:0016442; GO:0017148; GO:0017151; GO:0030424; GO:0030517; GO:0031047; GO:0031507; GO:0032838; GO:0035176; GO:0036464; GO:0042048; GO:0042127; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043186; GO:0043197; GO:0043204; GO:0043488; GO:0043621; GO:0045182; GO:0045448; GO:0045475; GO:0045727; GO:0045886; GO:0046627; GO:0046959; GO:0048134; GO:0048621; GO:0048812; GO:0048814; GO:0050774; GO:0050802; GO:0050807; GO:0050808; GO:0050976; GO:0051028; GO:0051823; GO:0051964; GO:0060998; GO:0070142; GO:0071598; GO:0072375; GO:0072553; GO:0090328; GO:0097091; GO:0098793; GO:0098883; GO:0099578; GO:1900073; GO:1900364; GO:1904115; GO:1905244; GO:1990124; GO:1990247; GO:1990834; GO:2000647 24762 FUN_028511 3047 2565 2028 5743 6451 ptg000021l:20839733-20842877 Q9NFU0 2.41e-23 Fragile X messenger ribonucleoprotein 1 homolog (dFMR1) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; anterograde axonal transport [GO:0008089]; associative learning [GO:0008306]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cellularization [GO:0007349]; central nervous system development [GO:0007417]; circadian rhythm [GO:0007623]; circadian sleep/wake cycle, sleep [GO:0050802]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; germ cell development [GO:0007281]; germ-line cyst formation [GO:0048134]; germarium-derived oocyte fate determination [GO:0007294]; grooming behavior [GO:0007625]; habituation [GO:0046959]; heterochromatin formation [GO:0031507]; larval locomotory behavior [GO:0008345]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; medium-term memory [GO:0072375]; mitotic cell cycle, embryonic [GO:0045448]; mRNA transport [GO:0051028]; mushroom body development [GO:0016319]; negative regulation of axon extension [GO:0030517]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of synapse assembly [GO:0051964]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; negative regulation of translation [GO:0017148]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; neuron remodeling [GO:0016322]; olfactory behavior [GO:0042048]; olfactory learning [GO:0008355]; oocyte dorsal/ventral axis specification [GO:0007310]; pole cell formation [GO:0007279]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of programmed cell death [GO:0043068]; positive regulation of translation [GO:0045727]; post-embryonic digestive tract morphogenesis [GO:0048621]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell population proliferation [GO:0042127]; regulation of dendrite morphogenesis [GO:0048814]; regulation of dendritic spine development [GO:0060998]; regulation of mitotic cell cycle, embryonic [GO:0009794]; regulation of modification of synaptic structure [GO:1905244]; regulation of mRNA stability [GO:0043488]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of olfactory learning [GO:0090328]; regulation of synapse organization [GO:0050807]; regulation of synapse structural plasticity [GO:0051823]; regulation of translation [GO:0006417]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to odorant [GO:1990834]; RNA-mediated gene silencing [GO:0031047]; short-term memory [GO:0007614]; social behavior [GO:0035176]; sperm axoneme assembly [GO:0007288]; synapse organization [GO:0050808]; synapse pruning [GO:0098883]; synaptic vesicle budding [GO:0070142]; synaptic vesicle clustering [GO:0097091]; terminal button organization [GO:0072553]; visual perception [GO:0007601] GO:0000139; GO:0000900; GO:0002052; GO:0003723; GO:0003730; GO:0005634; GO:0005737; GO:0005844; GO:0006417; GO:0007279; GO:0007281; GO:0007288; GO:0007294; GO:0007310; GO:0007349; GO:0007409; GO:0007411; GO:0007413; GO:0007417; GO:0007420; GO:0007528; GO:0007601; GO:0007614; GO:0007616; GO:0007623; GO:0007625; GO:0008049; GO:0008089; GO:0008306; GO:0008344; GO:0008345; GO:0008355; GO:0009794; GO:0010494; GO:0010608; GO:0010629; GO:0014069; GO:0016020; GO:0016319; GO:0016322; GO:0016442; GO:0017148; GO:0017151; GO:0030424; GO:0030517; GO:0031047; GO:0031507; GO:0032838; GO:0035176; GO:0036464; GO:0042048; GO:0042127; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043186; GO:0043197; GO:0043204; GO:0043488; GO:0043621; GO:0045182; GO:0045448; GO:0045475; GO:0045727; GO:0045886; GO:0046627; GO:0046959; GO:0048134; GO:0048621; GO:0048812; GO:0048814; GO:0050774; GO:0050802; GO:0050807; GO:0050808; GO:0050976; GO:0051028; GO:0051823; GO:0051964; GO:0060998; GO:0070142; GO:0071598; GO:0072375; GO:0072553; GO:0090328; GO:0097091; GO:0098793; GO:0098883; GO:0099578; GO:1900073; GO:1900364; GO:1904115; GO:1905244; GO:1990124; GO:1990247; GO:1990834; GO:2000647 24763 FUN_028511 3047 2565 2028 5743 6451 ptg000021l:20839733-20842877 Q9NFU0 2.41e-23 Fragile X messenger ribonucleoprotein 1 homolog (dFMR1) Drosophila melanogaster (Fruit fly) adult locomotory behavior [GO:0008344]; anterograde axonal transport [GO:0008089]; associative learning [GO:0008306]; axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; axonogenesis [GO:0007409]; brain development [GO:0007420]; cellularization [GO:0007349]; central nervous system development [GO:0007417]; circadian rhythm [GO:0007623]; circadian sleep/wake cycle, sleep [GO:0050802]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; germ cell development [GO:0007281]; germ-line cyst formation [GO:0048134]; germarium-derived oocyte fate determination [GO:0007294]; grooming behavior [GO:0007625]; habituation [GO:0046959]; heterochromatin formation [GO:0031507]; larval locomotory behavior [GO:0008345]; locomotor rhythm [GO:0045475]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; medium-term memory [GO:0072375]; mitotic cell cycle, embryonic [GO:0045448]; mRNA transport [GO:0051028]; mushroom body development [GO:0016319]; negative regulation of axon extension [GO:0030517]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of gene expression [GO:0010629]; negative regulation of insulin receptor signaling pathway [GO:0046627]; negative regulation of mRNA polyadenylation [GO:1900364]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of synapse assembly [GO:0051964]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; negative regulation of translation [GO:0017148]; neuromuscular junction development [GO:0007528]; neuron projection morphogenesis [GO:0048812]; neuron remodeling [GO:0016322]; olfactory behavior [GO:0042048]; olfactory learning [GO:0008355]; oocyte dorsal/ventral axis specification [GO:0007310]; pole cell formation [GO:0007279]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of programmed cell death [GO:0043068]; positive regulation of translation [GO:0045727]; post-embryonic digestive tract morphogenesis [GO:0048621]; post-transcriptional regulation of gene expression [GO:0010608]; regulation of cell population proliferation [GO:0042127]; regulation of dendrite morphogenesis [GO:0048814]; regulation of dendritic spine development [GO:0060998]; regulation of mitotic cell cycle, embryonic [GO:0009794]; regulation of modification of synaptic structure [GO:1905244]; regulation of mRNA stability [GO:0043488]; regulation of neuromuscular synaptic transmission [GO:1900073]; regulation of olfactory learning [GO:0090328]; regulation of synapse organization [GO:0050807]; regulation of synapse structural plasticity [GO:0051823]; regulation of translation [GO:0006417]; regulation of translation at postsynapse, modulating synaptic transmission [GO:0099578]; response to odorant [GO:1990834]; RNA-mediated gene silencing [GO:0031047]; short-term memory [GO:0007614]; social behavior [GO:0035176]; sperm axoneme assembly [GO:0007288]; synapse organization [GO:0050808]; synapse pruning [GO:0098883]; synaptic vesicle budding [GO:0070142]; synaptic vesicle clustering [GO:0097091]; terminal button organization [GO:0072553]; visual perception [GO:0007601] GO:0000139; GO:0000900; GO:0002052; GO:0003723; GO:0003730; GO:0005634; GO:0005737; GO:0005844; GO:0006417; GO:0007279; GO:0007281; GO:0007288; GO:0007294; GO:0007310; GO:0007349; GO:0007409; GO:0007411; GO:0007413; GO:0007417; GO:0007420; GO:0007528; GO:0007601; GO:0007614; GO:0007616; GO:0007623; GO:0007625; GO:0008049; GO:0008089; GO:0008306; GO:0008344; GO:0008345; GO:0008355; GO:0009794; GO:0010494; GO:0010608; GO:0010629; GO:0014069; GO:0016020; GO:0016319; GO:0016322; GO:0016442; GO:0017148; GO:0017151; GO:0030424; GO:0030517; GO:0031047; GO:0031507; GO:0032838; GO:0035176; GO:0036464; GO:0042048; GO:0042127; GO:0042802; GO:0042803; GO:0043005; GO:0043025; GO:0043068; GO:0043186; GO:0043197; GO:0043204; GO:0043488; GO:0043621; GO:0045182; GO:0045448; GO:0045475; GO:0045727; GO:0045886; GO:0046627; GO:0046959; GO:0048134; GO:0048621; GO:0048812; GO:0048814; GO:0050774; GO:0050802; GO:0050807; GO:0050808; GO:0050976; GO:0051028; GO:0051823; GO:0051964; GO:0060998; GO:0070142; GO:0071598; GO:0072375; GO:0072553; GO:0090328; GO:0097091; GO:0098793; GO:0098883; GO:0099578; GO:1900073; GO:1900364; GO:1904115; GO:1905244; GO:1990124; GO:1990247; GO:1990834; GO:2000647 24764 FUN_028512 111 327 61 139 36 NA NA NA NA NA NA NA 24765 FUN_028513 28 203 131 211 278 NA NA NA NA NA NA NA 24766 FUN_022050 1423 688 487 894 787 NA NA NA NA NA NA NA 24767 FUN_022057 206 168 129 223 147 ptg000016l:5127458-5128742 P23610 5.19e-28 40-kDa huntingtin-associated protein (HAP40) (CpG island protein) (Factor VIII intron 22 protein) Homo sapiens (Human) negative regulation of proteasomal protein catabolic process [GO:1901799]; vesicle cytoskeletal trafficking [GO:0099518] GO:0005634; GO:0005769; GO:0016604; GO:0099518; GO:1901799 24768 FUN_022059 465 475 443 446 728 NA NA NA NA NA NA NA 24769 FUN_022058 2990 3179 1441 2222 1596 NA NA NA NA NA NA NA 24770 FUN_010471 25 0 0 59 0 NA NA NA NA NA NA NA 24771 FUN_010473 1092 1049 853 1024 1475 NA NA NA NA NA NA NA 24772 FUN_014163 62 27 7 68 11 ptg000008l:32576165-32580985 P30825 8.63e-27 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-histidine import across plasma membrane [GO:1903810]; L-ornithine transmembrane transport [GO:1903352]; lysine transport [GO:0015819]; ornithine transport [GO:0015822]; positive regulation of T cell proliferation [GO:0042102]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0001618; GO:0005290; GO:0005886; GO:0006865; GO:0009925; GO:0015171; GO:0015174; GO:0015189; GO:0015807; GO:0015819; GO:0015822; GO:0016020; GO:0016323; GO:0016324; GO:0032991; GO:0042102; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1903352; GO:1903810; GO:1903826 24773 FUN_014166 25 90 37 178 20 ptg000008l:32623919-32627153 Q502K3 9.29e-22 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 24774 FUN_014167 136 134 128 327 141 ptg000008l:32627734-32636196 P18581 5.43e-76 Cationic amino acid transporter 2 (CAT-2) (CAT2) (20.5) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) (T-cell early activation protein) (TEA) Mus musculus (Mouse) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; establishment of localization in cell [GO:0051649]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; macrophage activation [GO:0042116]; nitric oxide biosynthetic process [GO:0006809]; nitric oxide production involved in inflammatory response [GO:0002537]; regulation of inflammatory response [GO:0050727]; regulation of macrophage activation [GO:0043030] GO:0000064; GO:0002537; GO:0005886; GO:0006809; GO:0006865; GO:0015171; GO:0015179; GO:0015189; GO:0015807; GO:0016020; GO:0030054; GO:0042116; GO:0043030; GO:0050727; GO:0051649; GO:0061459; GO:0089718; GO:0097638; GO:1902475; GO:1903352; GO:1903826 24775 FUN_014164 0 0 3 14 13 NA NA NA NA NA NA NA 24776 FUN_014165 1137 333 238 983 307 ptg000008l:32599795-32609589 P52569 4.64e-75 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 24777 FUN_014165 1137 333 238 983 307 ptg000008l:32599795-32609589 P52569 2.42e-24 Cationic amino acid transporter 2 (CAT-2) (CAT2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Homo sapiens (Human) amino acid import across plasma membrane [GO:0089718]; amino acid transport [GO:0006865]; L-alpha-amino acid transmembrane transport [GO:1902475]; L-amino acid transport [GO:0015807]; L-arginine import across plasma membrane [GO:0097638]; L-arginine transmembrane transport [GO:1903826]; L-ornithine transmembrane transport [GO:1903352]; transport across blood-brain barrier [GO:0150104] GO:0000064; GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0015179; GO:0015189; GO:0015807; GO:0030054; GO:0061459; GO:0089718; GO:0097638; GO:0150104; GO:1902475; GO:1903352; GO:1903826 24778 FUN_014168 1668 561 604 1627 515 NA NA NA NA NA NA NA 24779 FUN_014169 3956 3801 2455 3116 2735 NA NA NA NA NA NA NA 24780 FUN_026502 69 351 68 50 0 NA NA NA NA NA NA NA 24781 FUN_010475 100 1 82 35 463 NA NA NA NA NA NA NA 24782 FUN_030004 0 3 0 4 117 NA NA NA NA NA NA NA 24783 FUN_030001 0 8 0 0 0 NA NA NA NA NA NA NA 24784 FUN_030008 0 0 41 0 62 NA NA NA NA NA NA NA 24785 FUN_010476 4 0 0 0 83 NA NA NA NA NA NA NA 24786 FUN_024068 609 422 875 330 215 ptg000018l:1846740-1847837 Q6K332 1.53e-33 2-oxoglutarate-dependent dioxygenase 33 (EC 1.14.11.-) (Melatonin 2-hydroxylase) Oryza sativa subsp. japonica (Rice) NA GO:0005737; GO:0031418; GO:0046872; GO:0051213 24787 FUN_024068 609 422 875 330 215 ptg000018l:1846740-1847837 Q6K332 1.53e-33 2-oxoglutarate-dependent dioxygenase 33 (EC 1.14.11.-) (Melatonin 2-hydroxylase) Oryza sativa subsp. japonica (Rice) NA GO:0005737; GO:0031418; GO:0046872; GO:0051213 24788 FUN_024069 923 729 528 615 1471 ptg000018l:1849467-1907450 Q9P215 2.57e-34 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 24789 FUN_024069 923 729 528 615 1471 ptg000018l:1849467-1907450 Q9P215 2.57e-34 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 24790 FUN_024069 923 729 528 615 1471 ptg000018l:1849467-1907450 Q9P215 2.04e-27 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 24791 FUN_024063 95 67 85 74 90 NA NA NA NA NA NA NA 24792 FUN_024064 252 253 145 181 218 ptg000018l:1819324-1820811 B1AWN4 4.98e-27 Phospholipid-transporting ATPase VB (EC 7.6.2.1) Mus musculus (Mouse) lysosomal membrane organization [GO:0097212]; phospholipid translocation [GO:0045332] GO:0000287; GO:0005524; GO:0005765; GO:0005783; GO:0005789; GO:0005886; GO:0016887; GO:0031902; GO:0045332; GO:0097212; GO:0140326; GO:0140345; GO:0140351; GO:1990531 24793 FUN_024065 101 29 70 21 119 NA NA NA NA NA NA NA 24794 FUN_024066 201 237 126 219 153 ptg000018l:1833757-1835321 Q54RA4 1.19e-27 Probable iron/ascorbate oxidoreductase DDB_G0283291 (EC 1.14.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0046872; GO:0051213 24795 FUN_024067 417 576 974 469 429 ptg000018l:1840945-1842047 Q54RA4 2.75e-44 Probable iron/ascorbate oxidoreductase DDB_G0283291 (EC 1.14.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0046872; GO:0051213 24796 FUN_024067 417 576 974 469 429 ptg000018l:1840945-1842047 Q54RA4 2.75e-44 Probable iron/ascorbate oxidoreductase DDB_G0283291 (EC 1.14.-.-) Dictyostelium discoideum (Social amoeba) NA GO:0046872; GO:0051213 24797 FUN_043173 76 53 31 47 32 ptg000047l:4983827-4984901 P97288 4.19e-36 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) Mus musculus (Mouse) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting serotonin receptor signaling pathway [GO:0007198]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gamma-aminobutyric acid signaling pathway [GO:0007214]; regulation of appetite [GO:0032098] GO:0004993; GO:0005737; GO:0005768; GO:0005886; GO:0007187; GO:0007189; GO:0007198; GO:0007214; GO:0007268; GO:0016020; GO:0030425; GO:0030594; GO:0032098; GO:0045202; GO:0051378 24798 FUN_007105 53 18 70 60 57 NA NA NA NA NA NA NA 24799 FUN_007106 10 132 88 104 232 ptg000001l:20547740-20548643 P30975 1.86e-30 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 24800 FUN_043305 774 539 614 2 349 NA NA NA NA NA NA NA 24801 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 9.79e-64 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24802 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 3.9e-60 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24803 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 3.9e-60 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24804 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.05e-55 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24805 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 5.15e-54 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24806 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.29e-46 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24807 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.29e-46 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24808 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.02e-44 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24809 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 8.16e-41 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24810 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 2.36e-36 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24811 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 2.99e-35 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24812 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 3.39e-35 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24813 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.39e-31 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24814 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 2.05e-29 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24815 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 6.98e-27 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24816 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 2.34e-26 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24817 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 2.34e-26 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24818 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.63e-25 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24819 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.82e-23 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24820 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 1.82e-23 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24821 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 4.76e-22 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24822 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 7.11e-22 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24823 FUN_007100 3975 2138 2127 4893 6469 ptg000001l:20450892-20490337 O95714 8.13e-22 E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; intracellular protein transport [GO:0006886]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; spermatogenesis [GO:0007283] GO:0005085; GO:0005634; GO:0005654; GO:0005737; GO:0005814; GO:0005829; GO:0005886; GO:0006281; GO:0006886; GO:0006974; GO:0007283; GO:0008270; GO:0016020; GO:0016567; GO:0031625; GO:0032183; GO:0043161; GO:0061630 24824 FUN_043303 87 100 103 192 113 ptg000047l:6773488-6781649 Q9Z0S2 1.02e-25 LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2) Mus musculus (Mouse) anatomical structure formation involved in morphogenesis [GO:0048646]; axon extension [GO:0048675]; axon guidance [GO:0007411]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; dorsal/ventral pattern formation [GO:0009953]; hair follicle development [GO:0001942]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; mesoderm development [GO:0007498]; negative regulation of gene expression, epigenetic [GO:0045814]; negative regulation of neurogenesis [GO:0050768]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; olfactory bulb development [GO:0021772]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978] GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001843; GO:0001942; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0007399; GO:0007411; GO:0007420; GO:0007498; GO:0009953; GO:0021537; GO:0021772; GO:0021978; GO:0021987; GO:0022008; GO:0030182; GO:0043565; GO:0045199; GO:0045814; GO:0045893; GO:0045944; GO:0046872; GO:0048646; GO:0048675; GO:0050768; GO:0060041; GO:2000179; GO:2000678 24825 FUN_007102 100 0 114 57 145 NA NA NA NA NA NA NA 24826 FUN_007103 9 0 0 0 0 NA NA NA NA NA NA NA 24827 FUN_043808 0 0 34 0 37 NA NA NA NA NA NA NA 24828 FUN_023872 274 265 306 251 408 NA NA NA NA NA NA NA 24829 FUN_023873 69 23 12 15 69 NA NA NA NA NA NA NA 24830 FUN_023870 29 21 30 115 69 NA NA NA NA NA NA NA 24831 FUN_023871 386 644 117 637 258 NA NA NA NA NA NA NA 24832 FUN_023876 0 0 0 14 0 NA NA NA NA NA NA NA 24833 FUN_023874 0 0 0 0 6 ptg000017l:12304282-12306964 P84239 3.68e-84 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24834 FUN_023875 9 0 10 0 22 ptg000017l:12314693-12316807 Q6LAF1 5.15e-45 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 24835 FUN_031754 4018 324 89 3806 2169 ptg000023l:25013286-25079263 P21328 3.25e-28 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 24836 FUN_031755 142 92 77 101 102 NA NA NA NA NA NA NA 24837 FUN_031756 740 510 259 501 324 NA NA NA NA NA NA NA 24838 FUN_039568 17 0 0 0 53 NA NA NA NA NA NA NA 24839 FUN_031750 185 107 47 222 323 NA NA NA NA NA NA NA 24840 FUN_031751 1568 958 486 1016 1046 NA NA NA NA NA NA NA 24841 FUN_031752 447 376 315 227 391 NA NA NA NA NA NA NA 24842 FUN_031753 142 120 35 299 299 NA NA NA NA NA NA NA 24843 FUN_039562 721 300 204 1082 646 NA NA NA NA NA NA NA 24844 FUN_039561 473 99 251 692 798 NA NA NA NA NA NA NA 24845 FUN_039560 58 39 141 255 518 NA NA NA NA NA NA NA 24846 FUN_031759 73 32 31 27 41 NA NA NA NA NA NA NA 24847 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 2.58e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24848 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 2.58e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24849 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 6.07e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24850 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 6.07e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24851 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 5.2e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24852 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 5.2e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24853 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 1.89e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24854 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 1.89e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24855 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 2.25e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24856 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 2.25e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24857 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 5.48e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24858 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 5.48e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24859 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 1.68e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24860 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 1.68e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24861 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 5.08e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24862 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 9.61e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24863 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 9.61e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24864 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 1.28e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24865 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 2.16e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24866 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 6.21e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24867 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 4.34e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24868 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 7.67e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24869 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 2.38e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24870 FUN_005297 317 200 271 587 300 ntLink_8:33748642-33751057 Q96AY4 3.24e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 24871 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 1.1e-54 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24872 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 1.1e-54 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24873 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 1.1e-54 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24874 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 2.34e-52 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24875 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 4.48e-39 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24876 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 4.48e-39 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24877 FUN_039699 0 17 0 22 39 ptg000030l:2607368-2701911 P20825 4.48e-39 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 24878 FUN_039694 0 0 7 0 0 NA NA NA NA NA NA NA 24879 FUN_039696 0 0 0 0 12 NA NA NA NA NA NA NA 24880 FUN_039690 0 0 9 53 21 NA NA NA NA NA NA NA 24881 FUN_039693 6 77 69 0 137 NA NA NA NA NA NA NA 24882 FUN_039692 0 22 0 0 21 NA NA NA NA NA NA NA 24883 FUN_013350 2112 1280 884 2494 2112 ptg000008l:21553580-21570622 Q91736 1.53e-21 Ephrin type-B receptor 1-B (EC 2.7.10.1) (Tyrosine-protein kinase receptor XELK) Xenopus laevis (African clawed frog) axon guidance [GO:0007411]; cell chemotaxis [GO:0060326]; cell-substrate adhesion [GO:0031589]; dendritic spine development [GO:0060996]; dendritic spine morphogenesis [GO:0060997]; ephrin receptor signaling pathway [GO:0048013]; establishment of cell polarity [GO:0030010]; positive regulation of synapse assembly [GO:0051965]; protein autophosphorylation [GO:0046777]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of JNK cascade [GO:0046328] GO:0005005; GO:0005524; GO:0005886; GO:0007411; GO:0030010; GO:0030425; GO:0031589; GO:0031901; GO:0046328; GO:0046777; GO:0048013; GO:0051965; GO:0060326; GO:0060996; GO:0060997; GO:0070372 24884 FUN_013351 191 478 271 460 251 NA NA NA NA NA NA NA 24885 FUN_041232 65 8 18 116 42 NA NA NA NA NA NA NA 24886 FUN_026969 0 0 2 0 90 NA NA NA NA NA NA NA 24887 FUN_026968 0 16 0 0 0 NA NA NA NA NA NA NA 24888 FUN_026967 5 0 0 0 7 NA NA NA NA NA NA NA 24889 FUN_026964 12 0 0 0 0 NA NA NA NA NA NA NA 24890 FUN_013356 88 14 13 86 58 NA NA NA NA NA NA NA 24891 FUN_013359 2856 2390 1089 1726 993 NA NA NA NA NA NA NA 24892 FUN_037341 1348 1243 0 27 726 ptg000026l:8956279-9145881 P14381 1.25e-76 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24893 FUN_037341 1348 1243 0 27 726 ptg000026l:8956279-9145881 P14381 1.86e-42 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24894 FUN_037341 1348 1243 0 27 726 ptg000026l:8956279-9145881 P14381 1.86e-42 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24895 FUN_037341 1348 1243 0 27 726 ptg000026l:8956279-9145881 P14381 1.86e-42 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 24896 FUN_037340 916 603 0 0 278 NA NA NA NA NA NA NA 24897 FUN_037342 0 0 5 23 0 NA NA NA NA NA NA NA 24898 FUN_005468 50 83 36 81 68 NA NA NA NA NA NA NA 24899 FUN_005465 14 0 9 0 23 NA NA NA NA NA NA NA 24900 FUN_005464 3420 5045 2504 4124 1367 NA NA NA NA NA NA NA 24901 FUN_005467 4780 3161 3028 5679 5119 ntLink_8:35750464-35811646 Q25197 5.16e-29 Putative insulin-like peptide receptor (EC 2.7.10.1) Hydra vulgaris (Hydra) (Hydra attenuata) protein autophosphorylation [GO:0046777]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004714; GO:0005524; GO:0007169; GO:0016020; GO:0043548; GO:0043560; GO:0046777; GO:0046872 24902 FUN_005466 0 0 15 0 14 NA NA NA NA NA NA NA 24903 FUN_005463 0 0 0 401 0 NA NA NA NA NA NA NA 24904 FUN_043651 1280 668 286 841 524 NA NA NA NA NA NA NA 24905 FUN_001519 5600 2135 1560 2610 3314 NA NA NA NA NA NA NA 24906 FUN_001518 2238 2894 1447 2138 1189 NA NA NA NA NA NA NA 24907 FUN_001515 88 121 21 70 67 NA NA NA NA NA NA NA 24908 FUN_001514 0 0 5 0 15 NA NA NA NA NA NA NA 24909 FUN_001517 1501 1072 764 1443 1631 NA NA NA NA NA NA NA 24910 FUN_001516 37 22 0 26 4 NA NA NA NA NA NA NA 24911 FUN_001511 0 0 0 0 11 NA NA NA NA NA NA NA 24912 FUN_001510 125 89 52 56 50 ntLink_6:13103350-13103659 Q9CR50 2.62e-31 RING finger and CHY zinc finger domain-containing protein 1 (EC 2.3.2.27) (Androgen receptor N-terminal-interacting protein) (CH-rich-interacting match with PLAG1) (E3 ubiquitin-protein ligase Pirh2) (RING-type E3 ubiquitin transferase RCHY1) (Zinc finger protein 363) Mus musculus (Mouse) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein ubiquitination [GO:0031398]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0002039; GO:0005102; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006511; GO:0008270; GO:0016567; GO:0016607; GO:0031398; GO:0032436; GO:0042803; GO:0043231; GO:0051865; GO:0061630 24913 FUN_001513 0 0 8 0 8 NA NA NA NA NA NA NA 24914 FUN_023635 2661 1933 1129 3360 2300 NA NA NA NA NA NA NA 24915 FUN_007677 1114 1111 928 1140 794 NA NA NA NA NA NA NA 24916 FUN_008375 815 720 569 1098 369 ptg000002l:10884284-10890328 Q9BHM6 3.26e-24 Octopine dehydrogenase (OcDH) (EC 1.5.1.11) Pecten maximus (King scallop) (Pilgrim's clam) NA GO:0000166; GO:0047830 24917 FUN_026039 6695 1799 851 1257 3326 ptg000020l:4002718-4005478 C6FG12 5.68e-27 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 24918 FUN_026038 1428 1057 408 734 262 ptg000020l:3996772-4000006 A0JMH2 6.66e-34 Mitochondrial protein C2orf69 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005739; GO:0005759; GO:0070469 24919 FUN_026031 1461 1627 791 1615 709 NA NA NA NA NA NA NA 24920 FUN_026033 723 868 272 973 970 NA NA NA NA NA NA NA 24921 FUN_026032 1650 3177 1371 1642 2764 NA NA NA NA NA NA NA 24922 FUN_026035 2473 1681 1670 2554 1659 NA NA NA NA NA NA NA 24923 FUN_026034 2840 1175 1209 2046 1759 ptg000020l:3937620-3968277 Q9CQ24 2.42e-24 F-box only protein 36 Mus musculus (Mouse) NA NA 24924 FUN_026037 1839 2648 793 1307 3334 NA NA NA NA NA NA NA 24925 FUN_026036 69 308 77 340 265 NA NA NA NA NA NA NA 24926 FUN_004332 4116 3379 1929 3148 2156 ntLink_8:22022379-22037127 Q9UNH5 6.78e-21 Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; cilium assembly [GO:0060271]; microtubule cytoskeleton organization [GO:0000226]; positive regulation of cytokinesis [GO:0032467]; protein dephosphorylation [GO:0006470]; regulation of exit from mitosis [GO:0007096]; sensory perception of sound [GO:0007605] GO:0000226; GO:0000922; GO:0004722; GO:0004725; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0006470; GO:0007049; GO:0007096; GO:0007605; GO:0008138; GO:0016604; GO:0017018; GO:0032426; GO:0032467; GO:0051301; GO:0060091; GO:0060271; GO:0072686; GO:1902636 24927 FUN_004333 697 805 468 583 587 NA NA NA NA NA NA NA 24928 FUN_004330 478 512 309 322 376 NA NA NA NA NA NA NA 24929 FUN_004331 396 32 193 251 237 ntLink_8:22016678-22019822 Q9V9S7 1.41e-48 Rho GTPase-activating protein 100F (RhoGAP-100F) (Synapse defective protein 1 homolog) (Protein syd-1 homolog) Drosophila melanogaster (Fruit fly) activation of GTPase activity [GO:0090630]; axon extension involved in axon guidance [GO:0048846]; cell migration [GO:0016477]; cell projection organization [GO:0030030]; cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; presynaptic active zone organization [GO:1990709]; R7 cell development [GO:0045467]; regulation of Ras protein signal transduction [GO:0046578]; Rho protein signal transduction [GO:0007266]; synapse assembly [GO:0007416]; synaptic vesicle localization [GO:0097479] GO:0005096; GO:0007266; GO:0007416; GO:0016477; GO:0030030; GO:0031594; GO:0045467; GO:0046578; GO:0048786; GO:0048789; GO:0048790; GO:0048846; GO:0090630; GO:0097060; GO:0097479; GO:0098831; GO:1990709 24930 FUN_004336 189 76 165 158 80 NA NA NA NA NA NA NA 24931 FUN_004337 67 37 32 109 64 ntLink_8:22069316-22072325 P15388 3.97e-48 Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) Mus musculus (Mouse) cellular response to xenobiotic stimulus [GO:0071466]; cerebellum development [GO:0021549]; corpus callosum development [GO:0022038]; globus pallidus development [GO:0021759]; optic nerve development [GO:0021554]; positive regulation of ion transmembrane transport [GO:0034767]; positive regulation of potassium ion transmembrane transport [GO:1901381]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; regulation of potassium ion transmembrane transport [GO:1901379]; response to amine [GO:0014075]; response to auditory stimulus [GO:0010996]; response to fibroblast growth factor [GO:0071774]; response to light intensity [GO:0009642]; response to nerve growth factor [GO:1990089]; response to potassium ion [GO:0035864]; response to toxic substance [GO:0009636] GO:0005249; GO:0005251; GO:0008076; GO:0009636; GO:0009642; GO:0009986; GO:0010996; GO:0014075; GO:0016020; GO:0019894; GO:0021549; GO:0021554; GO:0021759; GO:0022038; GO:0030424; GO:0030425; GO:0030673; GO:0032589; GO:0032590; GO:0032809; GO:0034765; GO:0034767; GO:0035864; GO:0042734; GO:0043025; GO:0044305; GO:0044325; GO:0045211; GO:0051260; GO:0051262; GO:0071466; GO:0071774; GO:0071805; GO:0099508; GO:1901379; GO:1901381; GO:1903818; GO:1990089 24932 FUN_004334 166 221 103 199 130 NA NA NA NA NA NA NA 24933 FUN_004335 150 100 0 106 41 ntLink_8:22051404-22057749 P17972 4.36e-47 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 24934 FUN_004335 150 100 0 106 41 ntLink_8:22051404-22057749 P17972 5.2e-29 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 24935 FUN_004338 46 108 121 113 28 NA NA NA NA NA NA NA 24936 FUN_004339 173 18 156 27 625 ntLink_8:22086347-22089342 E9Q3T6 8.94e-79 PR domain zinc finger protein 14 (EC 2.1.1.-) (PR domain-containing protein 14) Mus musculus (Mouse) cell fate specification [GO:0001708]; cell morphogenesis [GO:0000902]; embryo implantation [GO:0007566]; epigenetic regulation of gene expression [GO:0040029]; fertilization [GO:0009566]; fibroblast growth factor receptor signaling pathway [GO:0008543]; germ cell development [GO:0007281]; germ-line stem cell population maintenance [GO:0030718]; histone H3-R26 methylation [GO:0034972]; homeostasis of number of cells within a tissue [GO:0048873]; inactivation of paternal X chromosome [GO:0060817]; inner cell mass cell fate commitment [GO:0001827]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of stem cell population maintenance [GO:1902459]; regulation of DNA methylation [GO:0044030]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; stem cell population maintenance [GO:0019827] GO:0000122; GO:0000902; GO:0000977; GO:0001227; GO:0001708; GO:0001827; GO:0003723; GO:0005634; GO:0005654; GO:0006357; GO:0007281; GO:0007566; GO:0008168; GO:0008543; GO:0009566; GO:0010468; GO:0019827; GO:0030718; GO:0031490; GO:0034972; GO:0040029; GO:0040037; GO:0044030; GO:0046872; GO:0048873; GO:0060817; GO:1902093; GO:1902459 24937 FUN_007827 574 36 242 69 368 ptg000002l:5119881-5146661 Q7RTR2 3.62e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 24938 FUN_007826 71 24 13 63 107 NA NA NA NA NA NA NA 24939 FUN_007825 108 2 31 1 127 NA NA NA NA NA NA NA 24940 FUN_007824 2386 1011 1026 1451 1992 NA NA NA NA NA NA NA 24941 FUN_007823 2615 1941 1622 2987 2596 ptg000002l:5085696-5096492 Q66L42 1.57e-68 Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) Mus musculus (Mouse) cell death [GO:0008219]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of apoptotic process [GO:0043065]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; protein phosphorylation [GO:0006468]; smoothened signaling pathway [GO:0007224] GO:0003714; GO:0004672; GO:0004674; GO:0004706; GO:0005524; GO:0005737; GO:0006468; GO:0007224; GO:0008219; GO:0018105; GO:0018107; GO:0043065; GO:0043425; GO:0043433; GO:0043507; GO:0045892; GO:0046330; GO:0106310 24942 FUN_007822 228 120 162 254 229 NA NA NA NA NA NA NA 24943 FUN_007821 3363 1495 1632 3102 2145 NA NA NA NA NA NA NA 24944 FUN_007820 614 375 231 345 380 NA NA NA NA NA NA NA 24945 FUN_032696 0 0 8 0 0 NA NA NA NA NA NA NA 24946 FUN_007829 65 81 459 95 44 NA NA NA NA NA NA NA 24947 FUN_005123 0 68 0 0 0 ntLink_8:31344459-31346849 P54965 2.49e-35 Conjugated bile acid hydrolase (CBAH) (EC 3.5.1.-) (Bile salt hydrolase) (BSH) (CBAH-1) (Choloylglycine hydrolase) (EC 3.5.1.24) Clostridium perfringens (strain 13 / Type A) bile acid biosynthetic process [GO:0006699] GO:0006699; GO:0045302; GO:0047742 24948 FUN_005124 49 0 22 1 106 NA NA NA NA NA NA NA 24949 FUN_005127 710 250 188 512 163 NA NA NA NA NA NA NA 24950 FUN_018493 497 769 180 1204 583 NA NA NA NA NA NA NA 24951 FUN_034069 17 56 13 395 741 NA NA NA NA NA NA NA 24952 FUN_018497 307 540 206 1807 2602 NA NA NA NA NA NA NA 24953 FUN_018494 0 3 0 6 1 NA NA NA NA NA NA NA 24954 FUN_018495 636 776 147 398 1584 NA NA NA NA NA NA NA 24955 FUN_034065 184 200 78 167 125 NA NA NA NA NA NA NA 24956 FUN_034064 17 103 0 152 120 ptg000024l:4384415-4434690 Q3ZCC3 4.13e-32 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 24957 FUN_034064 17 103 0 152 120 ptg000024l:4384415-4434690 Q3ZCC3 3.82e-31 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 24958 FUN_034064 17 103 0 152 120 ptg000024l:4384415-4434690 Q3ZCC3 4.07e-31 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Bos taurus (Bovine) activation of NF-kappaB-inducing kinase activity [GO:0007250]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone resorption [GO:0045453]; cellular response to DNA damage stimulus [GO:0006974]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0004842; GO:0005164; GO:0005634; GO:0005811; GO:0005829; GO:0005938; GO:0006974; GO:0007249; GO:0007250; GO:0008270; GO:0009898; GO:0019886; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031663; GO:0031666; GO:0031996; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045944; GO:0046330; GO:0047485; GO:0048471; GO:0050852; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0097400; GO:1901224; GO:1904996; GO:2000679 24959 FUN_018498 452 913 287 742 707 NA NA NA NA NA NA NA 24960 FUN_034066 0 0 3 92 87 NA NA NA NA NA NA NA 24961 FUN_034061 396 3556 903 1935 1622 NA NA NA NA NA NA NA 24962 FUN_034060 0 0 0 116 53 NA NA NA NA NA NA NA 24963 FUN_034063 6 0 8 18 235 NA NA NA NA NA NA NA 24964 FUN_034062 158 260 200 245 280 ptg000024l:4321919-4364238 Q94K49 1.45e-45 Protein ANTAGONIST OF LIKE HETEROCHROMATIN PROTEIN 1 (EC 3.1.-.-) Arabidopsis thaliana (Mouse-ear cress) epigenetic regulation of gene expression [GO:0040029] GO:0003682; GO:0004518; GO:0005634; GO:0035098; GO:0035102; GO:0040029; GO:0046872 24965 FUN_022525 1218 876 750 562 950 NA NA NA NA NA NA NA 24966 FUN_015184 5896 6257 2842 1447 953 NA NA NA NA NA NA NA 24967 FUN_007175 75 59 51 58 71 NA NA NA NA NA NA NA 24968 FUN_007174 2643 1771 1400 1340 1743 NA NA NA NA NA NA NA 24969 FUN_043333 269 42 6 61 43 NA NA NA NA NA NA NA 24970 FUN_007170 2232 2661 1251 1871 2047 NA NA NA NA NA NA NA 24971 FUN_043330 294 171 86 775 246 NA NA NA NA NA NA NA 24972 FUN_007179 185 75 0 54 42 NA NA NA NA NA NA NA 24973 FUN_007178 38 36 20 78 6 ptg000001l:21300295-21306214 B8VIU6 5.8e-34 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 24974 FUN_043339 34 0 0 3 0 NA NA NA NA NA NA NA 24975 FUN_043338 372 6 0 80 0 NA NA NA NA NA NA NA 24976 FUN_006889 662 822 906 887 661 NA NA NA NA NA NA NA 24977 FUN_006886 1349 793 833 1651 1403 ptg000001l:17953372-17961393 Q4VSN1 7.79e-68 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; notochord cell vacuolation [GO:0060036]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0060036; GO:0070161; GO:0070374; GO:0106310 24978 FUN_006886 1349 793 833 1651 1403 ptg000001l:17953372-17961393 Q4VSN1 4.07e-58 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; notochord cell vacuolation [GO:0060036]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0060036; GO:0070161; GO:0070374; GO:0106310 24979 FUN_006886 1349 793 833 1651 1403 ptg000001l:17953372-17961393 Q4VSN1 8.05e-38 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; notochord cell vacuolation [GO:0060036]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0060036; GO:0070161; GO:0070374; GO:0106310 24980 FUN_006886 1349 793 833 1651 1403 ptg000001l:17953372-17961393 Q4VSN1 1e-28 Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to fibroblast growth factor stimulus [GO:0044344]; embryonic organ development [GO:0048568]; negative regulation of apoptotic process [GO:0043066]; notochord cell vacuolation [GO:0060036]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of fibroblast growth factor receptor signaling pathway [GO:0045743] GO:0004674; GO:0004712; GO:0004713; GO:0005524; GO:0005737; GO:0016323; GO:0016324; GO:0043066; GO:0044344; GO:0045743; GO:0048568; GO:0060036; GO:0070161; GO:0070374; GO:0106310 24981 FUN_006887 29 19 0 18 46 NA NA NA NA NA NA NA 24982 FUN_006885 2388 1756 957 1810 1321 NA NA NA NA NA NA NA 24983 FUN_006883 74 248 111 95 156 NA NA NA NA NA NA NA 24984 FUN_006881 0 216 124 44 20 NA NA NA NA NA NA NA 24985 FUN_037418 1510 1354 799 1178 1074 NA NA NA NA NA NA NA 24986 FUN_034933 467 287 189 246 330 NA NA NA NA NA NA NA 24987 FUN_034932 12 0 14 1 23 NA NA NA NA NA NA NA 24988 FUN_034931 858 661 263 488 585 NA NA NA NA NA NA NA 24989 FUN_034930 2342 2308 1471 1913 1096 NA NA NA NA NA NA NA 24990 FUN_034937 6412 5603 4363 3748 2683 NA NA NA NA NA NA NA 24991 FUN_034936 2270 854 902 1047 1880 NA NA NA NA NA NA NA 24992 FUN_034935 3506 2609 1893 3160 2754 ptg000025l:1920261-1925993 Q8ND56 9.23e-27 Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A) Homo sapiens (Human) defense response to virus [GO:0051607]; mitotic spindle assembly [GO:0090307]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; RIG-I signaling pathway [GO:0039529]; stress granule assembly [GO:0034063] GO:0000932; GO:0003690; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0005737; GO:0005829; GO:0010494; GO:0017148; GO:0033962; GO:0034063; GO:0036464; GO:0039529; GO:0051607; GO:0060340; GO:0072686; GO:0090307; GO:1990124 24993 FUN_034935 3506 2609 1893 3160 2754 ptg000025l:1920261-1925993 Q8ND56 9.23e-27 Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A) Homo sapiens (Human) defense response to virus [GO:0051607]; mitotic spindle assembly [GO:0090307]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; RIG-I signaling pathway [GO:0039529]; stress granule assembly [GO:0034063] GO:0000932; GO:0003690; GO:0003723; GO:0003725; GO:0003727; GO:0003729; GO:0005737; GO:0005829; GO:0010494; GO:0017148; GO:0033962; GO:0034063; GO:0036464; GO:0039529; GO:0051607; GO:0060340; GO:0072686; GO:0090307; GO:1990124 24994 FUN_034939 3119 2945 1832 3104 1064 NA NA NA NA NA NA NA 24995 FUN_034938 5574 4368 3486 4848 1614 NA NA NA NA NA NA NA 24996 FUN_035086 113 23 68 99 81 ptg000025l:3601126-3604748 F6QEU4 2.97e-86 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 24997 FUN_035086 113 23 68 99 81 ptg000025l:3601126-3604748 F6QEU4 2.13e-23 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 24998 FUN_035087 110 95 153 121 36 ptg000025l:3608418-3610652 E7FAM5 9.93e-66 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 24999 FUN_035087 110 95 153 121 36 ptg000025l:3608418-3610652 E7FAM5 9.93e-66 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25000 FUN_035087 110 95 153 121 36 ptg000025l:3608418-3610652 E7FAM5 4.51e-31 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25001 FUN_035080 51 15 23 52 105 ptg000025l:3553659-3560665 E7FAM5 3.09e-88 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25002 FUN_035080 51 15 23 52 105 ptg000025l:3553659-3560665 E7FAM5 6.87e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25003 FUN_035080 51 15 23 52 105 ptg000025l:3553659-3560665 E7FAM5 6.87e-57 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25004 FUN_035081 17 0 14 19 15 ptg000025l:3561447-3565870 F6QEU4 5.71e-44 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25005 FUN_035081 17 0 14 19 15 ptg000025l:3561447-3565870 F6QEU4 2.49e-33 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25006 FUN_035081 17 0 14 19 15 ptg000025l:3561447-3565870 F6QEU4 2.7e-27 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25007 FUN_035082 0 0 75 13 23 ptg000025l:3566023-3569743 Q5BIM1 1.61e-21 Tripartite motif-containing protein 45 Bos taurus (Bovine) bone development [GO:0060348]; positive regulation of DNA-templated transcription [GO:0045893] GO:0000785; GO:0004842; GO:0005654; GO:0005829; GO:0008270; GO:0045171; GO:0045893; GO:0060348 25008 FUN_035083 160 55 164 160 239 ptg000025l:3573801-3583327 E7FAM5 7.2e-85 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25009 FUN_035083 160 55 164 160 239 ptg000025l:3573801-3583327 E7FAM5 6.33e-80 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25010 FUN_006228 952 537 573 1219 1353 NA NA NA NA NA NA NA 25011 FUN_006229 1067 583 579 721 566 NA NA NA NA NA NA NA 25012 FUN_006222 1433 902 771 526 449 ptg000001l:9360459-9364695 P19643 4.29e-70 Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) Rattus norvegicus (Rat) negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005741; GO:0008131; GO:0009410; GO:0009636; GO:0010044; GO:0010269; GO:0014063; GO:0032496; GO:0042135; GO:0042802; GO:0045471; GO:0045964; GO:0048545; GO:0050660; GO:0051412; GO:0052595; GO:0052596; GO:0097621 25013 FUN_006222 1433 902 771 526 449 ptg000001l:9360459-9364695 P19643 4.91e-23 Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) Rattus norvegicus (Rat) negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005741; GO:0008131; GO:0009410; GO:0009636; GO:0010044; GO:0010269; GO:0014063; GO:0032496; GO:0042135; GO:0042802; GO:0045471; GO:0045964; GO:0048545; GO:0050660; GO:0051412; GO:0052595; GO:0052596; GO:0097621 25014 FUN_006222 1433 902 771 526 449 ptg000001l:9360459-9364695 P19643 1.3e-21 Amine oxidase [flavin-containing] B (EC 1.4.3.21) (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B) Rattus norvegicus (Rat) negative regulation of serotonin secretion [GO:0014063]; neurotransmitter catabolic process [GO:0042135]; positive regulation of dopamine metabolic process [GO:0045964]; response to aluminum ion [GO:0010044]; response to corticosterone [GO:0051412]; response to ethanol [GO:0045471]; response to lipopolysaccharide [GO:0032496]; response to selenium ion [GO:0010269]; response to steroid hormone [GO:0048545]; response to toxic substance [GO:0009636]; response to xenobiotic stimulus [GO:0009410] GO:0005739; GO:0005741; GO:0008131; GO:0009410; GO:0009636; GO:0010044; GO:0010269; GO:0014063; GO:0032496; GO:0042135; GO:0042802; GO:0045471; GO:0045964; GO:0048545; GO:0050660; GO:0051412; GO:0052595; GO:0052596; GO:0097621 25015 FUN_006223 5453 2720 2913 3878 2389 NA NA NA NA NA NA NA 25016 FUN_006220 3489 1724 2261 1782 1531 NA NA NA NA NA NA NA 25017 FUN_006221 7533 10028 4651 9932 6618 NA NA NA NA NA NA NA 25018 FUN_006226 16 4 4 6 3 NA NA NA NA NA NA NA 25019 FUN_006227 3815 2460 1964 3794 3773 NA NA NA NA NA NA NA 25020 FUN_006224 0 4 0 510 479 NA NA NA NA NA NA NA 25021 FUN_006225 1096 0 0 0 1805 ptg000001l:9414765-9456959 C0H691 3.15e-22 Small cysteine-rich protein 2 (Amil-SCRiP2) (SCRiP2) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0042151; GO:0090729 25022 FUN_042060 825 432 390 545 746 NA NA NA NA NA NA NA 25023 FUN_042061 1222 953 1226 879 1003 NA NA NA NA NA NA NA 25024 FUN_042062 1833 1899 1637 1482 2525 NA NA NA NA NA NA NA 25025 FUN_042063 2 0 0 970 0 NA NA NA NA NA NA NA 25026 FUN_029229 14 5 12 8 90 NA NA NA NA NA NA NA 25027 FUN_040518 21 0 0 0 12 ptg000031l:9721468-9732151 Q95SX7 3.37e-22 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25028 FUN_040518 21 0 0 0 12 ptg000031l:9721468-9732151 Q95SX7 3.37e-22 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25029 FUN_040518 21 0 0 0 12 ptg000031l:9721468-9732151 Q95SX7 3.37e-22 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25030 FUN_040519 447 22 24 17 35 ptg000031l:9733166-9735407 Q7RTR2 2.88e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25031 FUN_040519 447 22 24 17 35 ptg000031l:9733166-9735407 Q7RTR2 1.36e-32 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25032 FUN_040519 447 22 24 17 35 ptg000031l:9733166-9735407 Q7RTR2 3.78e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25033 FUN_040519 447 22 24 17 35 ptg000031l:9733166-9735407 Q7RTR2 2.7e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25034 FUN_040519 447 22 24 17 35 ptg000031l:9733166-9735407 Q7RTR2 4.09e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25035 FUN_040519 447 22 24 17 35 ptg000031l:9733166-9735407 Q7RTR2 2.53e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25036 FUN_040516 50 0 0 17 20 NA NA NA NA NA NA NA 25037 FUN_040517 11 16 0 26 48 NA NA NA NA NA NA NA 25038 FUN_040515 386 0 164 164 0 ptg000031l:9668555-9681395 Q5DU56 2.82e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25039 FUN_040515 386 0 164 164 0 ptg000031l:9668555-9681395 Q5DU56 8.38e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25040 FUN_040515 386 0 164 164 0 ptg000031l:9668555-9681395 Q5DU56 1.57e-24 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25041 FUN_040512 17 10 13 16 21 NA NA NA NA NA NA NA 25042 FUN_040513 0 0 19 0 0 NA NA NA NA NA NA NA 25043 FUN_040510 446 4 0 0 236 ptg000031l:9605169-9611475 Q5DU56 1.45e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25044 FUN_040510 446 4 0 0 236 ptg000031l:9605169-9611475 Q5DU56 4.82e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25045 FUN_040511 221 0 25 88 55 NA NA NA NA NA NA NA 25046 FUN_029089 0 0 0 0 53 NA NA NA NA NA NA NA 25047 FUN_032963 635 710 301 1003 515 NA NA NA NA NA NA NA 25048 FUN_012937 11 2 31 2 59 NA NA NA NA NA NA NA 25049 FUN_012935 0 0 4 2 18 NA NA NA NA NA NA NA 25050 FUN_003836 0 6 0 6 26 NA NA NA NA NA NA NA 25051 FUN_012930 0 0 196 0 0 NA NA NA NA NA NA NA 25052 FUN_029082 26 0 39 4 0 NA NA NA NA NA NA NA 25053 FUN_032052 596 387 402 459 425 NA NA NA NA NA NA NA 25054 FUN_032053 1809 813 1427 1653 1970 NA NA NA NA NA NA NA 25055 FUN_032050 3816 1533 1777 2352 3018 NA NA NA NA NA NA NA 25056 FUN_032051 233 310 289 309 317 ptg000023l:28442714-28445985 Q91918 2.8e-39 DNA repair protein RAD51 homolog A (xRAD51.1) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA recombinase assembly [GO:0000730]; double-strand break repair via homologous recombination [GO:0000724]; mitotic recombination-dependent replication fork processing [GO:1990426] GO:0000150; GO:0000228; GO:0000724; GO:0000730; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006974; GO:0017116; GO:0140664; GO:1990426 25057 FUN_032051 233 310 289 309 317 ptg000023l:28442714-28445985 Q91918 5.35e-37 DNA repair protein RAD51 homolog A (xRAD51.1) Xenopus laevis (African clawed frog) cellular response to DNA damage stimulus [GO:0006974]; DNA recombinase assembly [GO:0000730]; double-strand break repair via homologous recombination [GO:0000724]; mitotic recombination-dependent replication fork processing [GO:1990426] GO:0000150; GO:0000228; GO:0000724; GO:0000730; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0006974; GO:0017116; GO:0140664; GO:1990426 25058 FUN_032056 365 202 128 412 293 NA NA NA NA NA NA NA 25059 FUN_032057 0 10 0 20 15 NA NA NA NA NA NA NA 25060 FUN_032054 9 82 50 121 60 NA NA NA NA NA NA NA 25061 FUN_032055 191 338 32 101 147 ptg000023l:28487487-28490091 Q9Z2L6 1.2e-37 Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) Mus musculus (Mouse) NA GO:0003993; GO:0005788; GO:0005886; GO:0030351; GO:0030352; GO:0034417; GO:0052745; GO:0052826 25062 FUN_032058 29 0 54 8 31 NA NA NA NA NA NA NA 25063 FUN_032059 23 59 42 35 81 NA NA NA NA NA NA NA 25064 FUN_040259 60 0 127 431 359 ptg000031l:6008140-6024709 P47970 3.8e-26 Neuronal pentraxin-2 (NP2) (Acrosomal pentaxin-like protein p50) (AM50) (Neuronal pentraxin II) (Apexin) (NP-II) Cavia porcellus (Guinea pig) NA GO:0043160; GO:0046872 25065 FUN_040259 60 0 127 431 359 ptg000031l:6008140-6024709 P47970 1.75e-24 Neuronal pentraxin-2 (NP2) (Acrosomal pentaxin-like protein p50) (AM50) (Neuronal pentraxin II) (Apexin) (NP-II) Cavia porcellus (Guinea pig) NA GO:0043160; GO:0046872 25066 FUN_040259 60 0 127 431 359 ptg000031l:6008140-6024709 P47970 3.25e-24 Neuronal pentraxin-2 (NP2) (Acrosomal pentaxin-like protein p50) (AM50) (Neuronal pentraxin II) (Apexin) (NP-II) Cavia porcellus (Guinea pig) NA GO:0043160; GO:0046872 25067 FUN_000318 3364 1353 1123 1570 2654 NA NA NA NA NA NA NA 25068 FUN_000319 1710 1132 604 1138 934 NA NA NA NA NA NA NA 25069 FUN_005149 38 0 0 24 0 NA NA NA NA NA NA NA 25070 FUN_005142 142 26 38 255 66 NA NA NA NA NA NA NA 25071 FUN_000312 305 148 26 153 102 NA NA NA NA NA NA NA 25072 FUN_000313 1320 408 238 769 375 NA NA NA NA NA NA NA 25073 FUN_000314 411 45 104 121 241 ntLink_6:1378823-1387838 Q9NBX4 4.23e-25 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25074 FUN_000314 411 45 104 121 241 ntLink_6:1378823-1387838 Q9NBX4 4.23e-25 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25075 FUN_000315 784 128 223 291 363 NA NA NA NA NA NA NA 25076 FUN_000316 2707 620 10 2188 1048 ntLink_6:1407486-1426569 P0CT39 2.67e-89 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 25077 FUN_000317 851 373 265 812 804 NA NA NA NA NA NA NA 25078 FUN_041744 8877 6873 6281 13921 10740 NA NA NA NA NA NA NA 25079 FUN_041745 14294 10272 2954 17581 13231 NA NA NA NA NA NA NA 25080 FUN_041746 92 31 41 125 91 NA NA NA NA NA NA NA 25081 FUN_041740 766 377 426 564 281 ptg000035l:6982426-6986581 P84079 3.8e-76 ADP-ribosylation factor 1 (EC 3.6.5.2) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0000287; GO:0002090; GO:0003924; GO:0005525; GO:0005737; GO:0005770; GO:0005794; GO:0005829; GO:0005886; GO:0006878; GO:0006886; GO:0007015; GO:0012505; GO:0014069; GO:0016192; GO:0019003; GO:0019904; GO:0030017; GO:0031252; GO:0032991; GO:0034315; GO:0034379; GO:0043005; GO:0045807; GO:0045956; GO:0050714; GO:0055108; GO:0060292; GO:0060999; GO:0070142; GO:0097061; GO:0097212; GO:0098586; GO:0098974; GO:0098978; GO:1902307; GO:1902824; GO:1902953; GO:1903725; GO:1990386; GO:1990583 25082 FUN_041741 1268 865 591 1224 1365 ptg000035l:6987839-7024387 Q99315 7.27e-80 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 25083 FUN_041741 1268 865 591 1224 1365 ptg000035l:6987839-7024387 Q99315 7.27e-80 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 25084 FUN_041741 1268 865 591 1224 1365 ptg000035l:6987839-7024387 Q99315 7.27e-80 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 25085 FUN_041742 1516 835 780 849 413 ptg000035l:7025847-7027894 A0JPI9 1.11e-72 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 25086 FUN_041743 126205 103598 84108 191570 150160 NA NA NA NA NA NA NA 25087 FUN_005667 0 0 1 0 9 NA NA NA NA NA NA NA 25088 FUN_041749 140 29 35 184 220 NA NA NA NA NA NA NA 25089 FUN_008678 16 0 0 0 0 NA NA NA NA NA NA NA 25090 FUN_008677 29 0 24 0 17 NA NA NA NA NA NA NA 25091 FUN_008675 9 0 0 23 28 NA NA NA NA NA NA NA 25092 FUN_008674 8 0 14 9 7 NA NA NA NA NA NA NA 25093 FUN_008673 0 0 13 0 0 NA NA NA NA NA NA NA 25094 FUN_008672 141 0 60 0 52 NA NA NA NA NA NA NA 25095 FUN_008670 0 0 0 0 17 NA NA NA NA NA NA NA 25096 FUN_029029 6 170 44 57 12 NA NA NA NA NA NA NA 25097 FUN_029028 28 12 49 34 18 NA NA NA NA NA NA NA 25098 FUN_029027 101 84 31 117 73 NA NA NA NA NA NA NA 25099 FUN_029026 229 204 148 214 207 ptg000022l:7387211-7388661 Q93075 3.64e-82 Putative deoxyribonuclease TATDN2 (EC 3.1.21.-) Homo sapiens (Human) NA GO:0004518; GO:0005654; GO:0046872 25100 FUN_029025 3222 3466 1785 2156 2068 NA NA NA NA NA NA NA 25101 FUN_029024 414 198 267 450 296 NA NA NA NA NA NA NA 25102 FUN_029023 23 11 24 99 74 NA NA NA NA NA NA NA 25103 FUN_029022 247 52 94 187 66 NA NA NA NA NA NA NA 25104 FUN_029021 861 299 364 640 298 NA NA NA NA NA NA NA 25105 FUN_029020 1379 946 626 997 1738 NA NA NA NA NA NA NA 25106 FUN_017783 2310 1532 1198 2024 2368 NA NA NA NA NA NA NA 25107 FUN_016898 0 0 0 11 0 NA NA NA NA NA NA NA 25108 FUN_018570 0 0 0 6 4 NA NA NA NA NA NA NA 25109 FUN_016894 49 22 0 0 19 NA NA NA NA NA NA NA 25110 FUN_016895 11 0 9 8 15 NA NA NA NA NA NA NA 25111 FUN_016896 131 70 99 337 471 NA NA NA NA NA NA NA 25112 FUN_016897 2244 698 1093 1006 438 NA NA NA NA NA NA NA 25113 FUN_016890 942 1050 4 1076 873 NA NA NA NA NA NA NA 25114 FUN_017781 2724 2038 1767 2347 1629 ptg000012l:336418-340674 Q5NVM9 8.96e-125 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; RNA splicing [GO:0008380] GO:0000974; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0016787; GO:0042470; GO:0045892; GO:0140662; GO:1990904 25115 FUN_017781 2724 2038 1767 2347 1629 ptg000012l:336418-340674 Q5NVM9 1.93e-54 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; RNA splicing [GO:0008380] GO:0000974; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0016787; GO:0042470; GO:0045892; GO:0140662; GO:1990904 25116 FUN_017781 2724 2038 1767 2347 1629 ptg000012l:336418-340674 Q5NVM9 4.22e-42 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; RNA splicing [GO:0008380] GO:0000974; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0016787; GO:0042470; GO:0045892; GO:0140662; GO:1990904 25117 FUN_017781 2724 2038 1767 2347 1629 ptg000012l:336418-340674 Q5NVM9 4.22e-42 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; negative regulation of DNA-templated transcription [GO:0045892]; RNA splicing [GO:0008380] GO:0000974; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0016787; GO:0042470; GO:0045892; GO:0140662; GO:1990904 25118 FUN_016892 2015 1869 22 3737 1467 NA NA NA NA NA NA NA 25119 FUN_016893 0 0 0 0 70 NA NA NA NA NA NA NA 25120 FUN_028990 126 58 85 117 125 ptg000022l:6866243-6868984 B8VIU6 3.78e-36 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25121 FUN_028991 196 77 15 232 66 ptg000022l:6870298-6875715 B8VIU6 4.23e-38 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25122 FUN_028992 58 28 73 80 64 NA NA NA NA NA NA NA 25123 FUN_033016 409 189 195 348 571 NA NA NA NA NA NA NA 25124 FUN_033011 195 41 49 89 56 NA NA NA NA NA NA NA 25125 FUN_028995 5 4 43 27 0 NA NA NA NA NA NA NA 25126 FUN_028996 25 29 17 3 21 NA NA NA NA NA NA NA 25127 FUN_028997 0 0 21 0 0 NA NA NA NA NA NA NA 25128 FUN_028998 44 0 70 70 60 NA NA NA NA NA NA NA 25129 FUN_033019 81 0 17 5 27 NA NA NA NA NA NA NA 25130 FUN_033018 3321 397 330 9 238 NA NA NA NA NA NA NA 25131 FUN_018574 14 0 0 7 3 NA NA NA NA NA NA NA 25132 FUN_017784 9931 10204 5710 6766 3773 NA NA NA NA NA NA NA 25133 FUN_016766 0 0 86 7 9 ptg000011l:7226149-7233345 Q96AY4 6.5e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25134 FUN_016766 0 0 86 7 9 ptg000011l:7226149-7233345 Q96AY4 7.41e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25135 FUN_016766 0 0 86 7 9 ptg000011l:7226149-7233345 Q96AY4 5.27e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25136 FUN_016766 0 0 86 7 9 ptg000011l:7226149-7233345 Q96AY4 5.71e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25137 FUN_042807 11287 10298 6206 8491 6086 ptg000047l:300003-317866 Q95SX7 4.81e-32 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25138 FUN_042807 11287 10298 6206 8491 6086 ptg000047l:300003-317866 Q95SX7 4.81e-32 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25139 FUN_042802 173 400 256 385 1082 NA NA NA NA NA NA NA 25140 FUN_042800 182 424 252 419 1155 NA NA NA NA NA NA NA 25141 FUN_029596 350 153 112 122 122 ptg000023l:3588318-3590490 E7FAM5 7.27e-53 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25142 FUN_003661 5 0 99 12 14 NA NA NA NA NA NA NA 25143 FUN_003660 0 0 0 6 0 NA NA NA NA NA NA NA 25144 FUN_042809 278 261 317 346 310 ptg000047l:325556-327916 P15206 6.85e-51 G2/mitotic-specific cyclin-B Marthasterias glacialis (Spiny starfish) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0016538; GO:0044772; GO:0051301 25145 FUN_012410 6798 3729 2410 4303 3134 NA NA NA NA NA NA NA 25146 FUN_029592 208 21 45 79 64 ptg000023l:3560672-3562826 F6QEU4 1.68e-53 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25147 FUN_029591 135 135 92 74 359 ptg000023l:3553015-3554569 D2GXS7 8.49e-34 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Ailuropoda melanoleuca (Giant panda) regulation of neuron apoptotic process [GO:0043523] GO:0004842; GO:0005737; GO:0008270; GO:0043523 25148 FUN_029590 105 28 16 54 18 NA NA NA NA NA NA NA 25149 FUN_028378 12 0 8 27 0 NA NA NA NA NA NA NA 25150 FUN_028379 0 20 48 63 13 NA NA NA NA NA NA NA 25151 FUN_010649 14 5 2 101 138 ptg000007l:1166885-1172235 D9IQ16 6.45e-32 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25152 FUN_010649 14 5 2 101 138 ptg000007l:1166885-1172235 D9IQ16 6.26e-31 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25153 FUN_010649 14 5 2 101 138 ptg000007l:1166885-1172235 D9IQ16 4.47e-30 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25154 FUN_010649 14 5 2 101 138 ptg000007l:1166885-1172235 D9IQ16 9.44e-29 Galaxin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 25155 FUN_028375 0 7 0 0 0 NA NA NA NA NA NA NA 25156 FUN_010645 0 6 19 21 10 NA NA NA NA NA NA NA 25157 FUN_010644 563 89 224 321 534 ptg000007l:1137877-1141158 Q7L266 1.73e-22 Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain] Homo sapiens (Human) asparagine catabolic process via L-aspartate [GO:0033345]; proteolysis [GO:0006508] GO:0001917; GO:0004067; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0008798; GO:0033345 25158 FUN_010643 333 167 225 347 235 ptg000007l:1133565-1136233 Q6GM78 4.5e-22 Isoaspartyl peptidase/L-asparaginase (EC 3.4.19.5) (EC 3.5.1.1) (Asparaginase-like protein 1) (Beta-aspartyl-peptidase) (Isoaspartyl dipeptidase) (L-asparagine amidohydrolase) [Cleaved into: Isoaspartyl peptidase/L-asparaginase alpha chain; Isoaspartyl peptidase/L-asparaginase beta chain] Xenopus laevis (African clawed frog) asparagine catabolic process via L-aspartate [GO:0033345]; proteolysis [GO:0006508] GO:0001917; GO:0004067; GO:0005737; GO:0006508; GO:0008798; GO:0033345 25159 FUN_010642 3037 1794 1230 2638 3255 NA NA NA NA NA NA NA 25160 FUN_010640 4417 6326 3685 4080 2971 ptg000007l:1098142-1102971 Q6GL89 5.64e-29 Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to amino acid starvation [GO:0034198]; cellular response to UV [GO:0034644]; negative regulation of translational initiation in response to stress [GO:0032057]; PERK-mediated unfolded protein response [GO:0036499]; response to endoplasmic reticulum stress [GO:0034976] GO:0003723; GO:0003743; GO:0005737; GO:0010494; GO:0032057; GO:0034198; GO:0034644; GO:0034976; GO:0036499 25161 FUN_010640 4417 6326 3685 4080 2971 ptg000007l:1098142-1102971 Q6GL89 4.38e-23 Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to amino acid starvation [GO:0034198]; cellular response to UV [GO:0034644]; negative regulation of translational initiation in response to stress [GO:0032057]; PERK-mediated unfolded protein response [GO:0036499]; response to endoplasmic reticulum stress [GO:0034976] GO:0003723; GO:0003743; GO:0005737; GO:0010494; GO:0032057; GO:0034198; GO:0034644; GO:0034976; GO:0036499 25162 FUN_006844 835 679 396 461 284 NA NA NA NA NA NA NA 25163 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 9.16e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25164 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 4.72e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25165 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 9.41e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25166 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 1.85e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25167 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 1.77e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25168 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 1.24e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25169 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 4.54e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25170 FUN_031424 60 0 11 13 17 ptg000023l:21071074-21211214 Q7RTR2 1.67e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25171 FUN_031425 120 147 65 52 73 ptg000023l:21214253-21219988 B9IUR6 3.14e-45 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain Q1) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 25172 FUN_016784 904 288 296 329 354 NA NA NA NA NA NA NA 25173 FUN_004658 48 14 19 32 2 NA NA NA NA NA NA NA 25174 FUN_040059 23258 20647 17082 22659 28190 NA NA NA NA NA NA NA 25175 FUN_040052 114 10 27 80 108 ptg000031l:3591370-3603872 P25291 1.83e-26 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 25176 FUN_040052 114 10 27 80 108 ptg000031l:3591370-3603872 P25291 1.6e-22 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 25177 FUN_004653 785 386 409 777 353 NA NA NA NA NA NA NA 25178 FUN_031651 799 1605 692 1214 871 ptg000023l:23908841-23913373 Q03555 5.05e-150 Gephyrin (Putative glycine receptor-tubulin linker protein) [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] Rattus norvegicus (Rat) establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein targeting [GO:0006605]; response to metal ion [GO:0010038]; synapse assembly [GO:0007416] GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006605; GO:0006777; GO:0007416; GO:0007529; GO:0008940; GO:0010038; GO:0014069; GO:0015631; GO:0018315; GO:0030425; GO:0030674; GO:0031234; GO:0032324; GO:0042802; GO:0043025; GO:0043546; GO:0045184; GO:0045202; GO:0045211; GO:0046872; GO:0060077; GO:0060090; GO:0061598; GO:0061599; GO:0072579; GO:0097060; GO:0097112; GO:0098690; GO:0098794; GO:0098970; GO:0098982; GO:0099091; GO:0099572; GO:0099634; GO:0099645 25179 FUN_031651 799 1605 692 1214 871 ptg000023l:23908841-23913373 Q03555 2.86e-47 Gephyrin (Putative glycine receptor-tubulin linker protein) [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] Rattus norvegicus (Rat) establishment of protein localization [GO:0045184]; establishment of synaptic specificity at neuromuscular junction [GO:0007529]; gamma-aminobutyric acid receptor clustering [GO:0097112]; glycine receptor clustering [GO:0072579]; Mo-molybdopterin cofactor biosynthetic process [GO:0006777]; molybdenum incorporation into molybdenum-molybdopterin complex [GO:0018315]; molybdopterin cofactor biosynthetic process [GO:0032324]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic neurotransmitter receptor diffusion trapping [GO:0098970]; protein targeting [GO:0006605]; response to metal ion [GO:0010038]; synapse assembly [GO:0007416] GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005856; GO:0006605; GO:0006777; GO:0007416; GO:0007529; GO:0008940; GO:0010038; GO:0014069; GO:0015631; GO:0018315; GO:0030425; GO:0030674; GO:0031234; GO:0032324; GO:0042802; GO:0043025; GO:0043546; GO:0045184; GO:0045202; GO:0045211; GO:0046872; GO:0060077; GO:0060090; GO:0061598; GO:0061599; GO:0072579; GO:0097060; GO:0097112; GO:0098690; GO:0098794; GO:0098970; GO:0098982; GO:0099091; GO:0099572; GO:0099634; GO:0099645 25180 FUN_040050 835 895 295 338 253 NA NA NA NA NA NA NA 25181 FUN_036606 0 51 0 45 2 NA NA NA NA NA NA NA 25182 FUN_016788 521 554 285 774 396 NA NA NA NA NA NA NA 25183 FUN_040056 0 149 0 119 0 NA NA NA NA NA NA NA 25184 FUN_031652 1595 829 707 591 1530 NA NA NA NA NA NA NA 25185 FUN_043078 36 41 9 80 50 NA NA NA NA NA NA NA 25186 FUN_043079 8 14 23 31 70 NA NA NA NA NA NA NA 25187 FUN_011514 0 0 0 0 8 NA NA NA NA NA NA NA 25188 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 9.98e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25189 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 1.59e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25190 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 5.61e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25191 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 3.73e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25192 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 6.32e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25193 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 1.62e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25194 FUN_043075 29 8 10 71 36 ptg000047l:3770268-3773769 Q96AY4 3.23e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25195 FUN_043076 8 0 6 0 64 NA NA NA NA NA NA NA 25196 FUN_011517 0 0 0 0 30 NA NA NA NA NA NA NA 25197 FUN_043070 104 28 74 186 94 ptg000047l:3689074-3692478 Q96AY4 1.53e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25198 FUN_043070 104 28 74 186 94 ptg000047l:3689074-3692478 Q96AY4 1.08e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25199 FUN_043070 104 28 74 186 94 ptg000047l:3689074-3692478 Q96AY4 1.1e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25200 FUN_043070 104 28 74 186 94 ptg000047l:3689074-3692478 Q96AY4 2.74e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25201 FUN_043070 104 28 74 186 94 ptg000047l:3689074-3692478 Q96AY4 9.57e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25202 FUN_043070 104 28 74 186 94 ptg000047l:3689074-3692478 Q96AY4 2.14e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25203 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 1.65e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25204 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 2.18e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25205 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 5.39e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25206 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 3e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25207 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 6.31e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25208 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 1.36e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25209 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 1.83e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25210 FUN_043073 89 28 12 116 78 ptg000047l:3730489-3737048 Q96AY4 7.46e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25211 FUN_031657 413 153 206 393 519 ptg000023l:24032818-24047927 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 25212 FUN_031657 413 153 206 393 519 ptg000023l:24032818-24047927 Q9NZJ4 2.44e-59 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 25213 FUN_031657 413 153 206 393 519 ptg000023l:24032818-24047927 Q9NZJ4 5.16e-55 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 25214 FUN_031656 32 0 18 0 42 NA NA NA NA NA NA NA 25215 FUN_013606 731 361 255 328 455 ptg000008l:24450601-24462249 P42898 1.64e-62 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Homo sapiens (Human) heterochromatin organization [GO:0070828]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; regulation of histone methylation [GO:0031060]; response to amino acid [GO:0043200]; response to folic acid [GO:0051593]; response to hypoxia [GO:0001666]; response to interleukin-1 [GO:0070555]; response to vitamin B2 [GO:0033274]; response to xenobiotic stimulus [GO:0009410]; S-adenosylmethionine metabolic process [GO:0046500]; tetrahydrofolate interconversion [GO:0035999] GO:0001666; GO:0001843; GO:0004489; GO:0005829; GO:0006555; GO:0009086; GO:0009410; GO:0031060; GO:0033274; GO:0035999; GO:0043200; GO:0044877; GO:0045202; GO:0046500; GO:0050660; GO:0050661; GO:0050667; GO:0051593; GO:0070555; GO:0070828; GO:0071949; GO:0072341; GO:0106313 25216 FUN_013604 560 70 112 1319 912 ptg000008l:24425758-24429564 Q9TRC7 1.8e-142 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 25217 FUN_013604 560 70 112 1319 912 ptg000008l:24425758-24429564 Q9TRC7 5.66e-21 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 25218 FUN_013605 259 200 164 435 327 ptg000008l:24432566-24444221 Q6NYE2 1.27e-24 Protein RCC2 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; negative regulation of GTPase activity [GO:0034260]; neural crest cell migration [GO:0001755] GO:0000775; GO:0001755; GO:0005730; GO:0005737; GO:0005819; GO:0005886; GO:0007049; GO:0016020; GO:0030496; GO:0031267; GO:0034260; GO:0051301 25219 FUN_013602 0 50 24 0 0 NA NA NA NA NA NA NA 25220 FUN_013603 840 463 176 559 475 NA NA NA NA NA NA NA 25221 FUN_013600 161 39 36 43 84 NA NA NA NA NA NA NA 25222 FUN_013601 192 210 289 292 140 NA NA NA NA NA NA NA 25223 FUN_013608 94 0 104 230 165 NA NA NA NA NA NA NA 25224 FUN_013609 54 15 0 13 101 NA NA NA NA NA NA NA 25225 FUN_029568 9 14 55 33 93 NA NA NA NA NA NA NA 25226 FUN_029569 70 240 56 41 234 NA NA NA NA NA NA NA 25227 FUN_029563 0 38 0 0 0 NA NA NA NA NA NA NA 25228 FUN_029560 178 410 104 109 35 ptg000023l:3374212-3378012 F6QEU4 3.12e-33 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 25229 FUN_029561 17 0 0 0 0 NA NA NA NA NA NA NA 25230 FUN_029566 338 66 152 146 169 ptg000023l:3403390-3405385 E7FAM5 7.59e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25231 FUN_029567 62 0 5 41 15 ptg000023l:3414417-3417070 P30975 1.46e-24 Tachykinin-like peptides receptor 99D (Tachykinin-like receptor at 99D) (dTKR) Drosophila melanogaster (Fruit fly) detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of synaptic transmission [GO:0050805]; neuropeptide signaling pathway [GO:0007218]; olfactory behavior [GO:0042048]; positive regulation of sensory perception of pain [GO:1904058]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0007186; GO:0007217; GO:0007218; GO:0008188; GO:0016020; GO:0042048; GO:0050805; GO:0050911; GO:1904058 25232 FUN_029564 332 375 113 263 78 ptg000023l:3388839-3391005 E7FAM5 9.52e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25233 FUN_029565 1651 1316 972 842 694 ptg000023l:3396532-3398707 E7FAM5 3.12e-52 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 25234 FUN_023689 1824 838 1170 1451 1615 NA NA NA NA NA NA NA 25235 FUN_023688 201 351 209 191 467 ptg000017l:10637878-10642328 Q5SWK7 6.64e-29 RING finger protein 145 (EC 2.3.2.27) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0008270; GO:0012505; GO:0061630 25236 FUN_023688 201 351 209 191 467 ptg000017l:10637878-10642328 Q5SWK7 4.98e-23 RING finger protein 145 (EC 2.3.2.27) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0008270; GO:0012505; GO:0061630 25237 FUN_023681 113 138 114 128 251 NA NA NA NA NA NA NA 25238 FUN_023680 2 2 1 6 2 NA NA NA NA NA NA NA 25239 FUN_023683 56 64 46 68 43 NA NA NA NA NA NA NA 25240 FUN_023682 5781 3454 3556 5661 5647 ptg000017l:10572012-10589010 A7SK48 1.3e-23 Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732]; translation reinitiation [GO:0002188] GO:0001732; GO:0002188; GO:0003729; GO:0003743; GO:0016282; GO:0033290; GO:0043614; GO:0071540; GO:0071541 25241 FUN_023684 347 365 205 294 312 NA NA NA NA NA NA NA 25242 FUN_023687 138 100 62 517 53 NA NA NA NA NA NA NA 25243 FUN_025903 1062 226 490 256 494 ptg000020l:1744392-1748219 Q86W24 6.94e-39 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 25244 FUN_025903 1062 226 490 256 494 ptg000020l:1744392-1748219 Q86W24 3.19e-33 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 25245 FUN_025904 301 162 303 6 31 NA NA NA NA NA NA NA 25246 FUN_025905 1823 184 300 194 231 ptg000020l:1766839-1769278 Q8K3Z0 7.46e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 25247 FUN_025906 453 85 149 110 413 ptg000020l:1774652-1782782 Q86W24 6.27e-36 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 25248 FUN_025906 453 85 149 110 413 ptg000020l:1774652-1782782 Q86W24 1.38e-34 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 25249 FUN_025906 453 85 149 110 413 ptg000020l:1774652-1782782 Q86W24 1.78e-30 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 25250 FUN_025906 453 85 149 110 413 ptg000020l:1774652-1782782 Q86W24 2.72e-21 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 25251 FUN_025908 58 50 17 26 145 NA NA NA NA NA NA NA 25252 FUN_025909 720 517 981 269 1088 ptg000020l:1794594-1859191 Q5ZM41 1.17e-34 Testis-expressed protein 10 homolog Gallus gallus (Chicken) NA GO:0005634; GO:0005730; GO:0071339 25253 FUN_025909 720 517 981 269 1088 ptg000020l:1794594-1859191 Q5ZM41 2.34e-26 Testis-expressed protein 10 homolog Gallus gallus (Chicken) NA GO:0005634; GO:0005730; GO:0071339 25254 FUN_003444 184 0 0 35 0 NA NA NA NA NA NA NA 25255 FUN_017877 68 52 20 89 111 NA NA NA NA NA NA NA 25256 FUN_031034 0 0 0 17 8 NA NA NA NA NA NA NA 25257 FUN_023533 22 103 31 42 73 NA NA NA NA NA NA NA 25258 FUN_023532 0 22 15 16 0 NA NA NA NA NA NA NA 25259 FUN_023535 165 59 286 88 97 NA NA NA NA NA NA NA 25260 FUN_023534 52 51 135 36 46 NA NA NA NA NA NA NA 25261 FUN_023539 0 0 0 0 54 NA NA NA NA NA NA NA 25262 FUN_023538 1 0 3 14 2 NA NA NA NA NA NA NA 25263 FUN_039880 225 107 249 282 605 NA NA NA NA NA NA NA 25264 FUN_039881 972 725 523 750 902 NA NA NA NA NA NA NA 25265 FUN_039882 2032 1533 982 1940 1310 NA NA NA NA NA NA NA 25266 FUN_039883 3539 2182 1722 2829 2384 ptg000031l:1308197-1326519 Q9BZQ6 1.36e-21 ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; protein glycosylation [GO:0006486]; response to unfolded protein [GO:0006986] GO:0004559; GO:0004571; GO:0005509; GO:0005783; GO:0005788; GO:0005975; GO:0006486; GO:0006986; GO:0016020; GO:0044322; GO:1904380; GO:1904382 25267 FUN_039884 1824 1806 1233 1630 732 ptg000031l:1328444-1330116 Q9CPW7 7.49e-49 Zinc finger matrin-type protein 2 Mus musculus (Mouse) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003677; GO:0005634; GO:0008270; GO:0046540; GO:0071005 25268 FUN_039885 2961 2352 1780 2593 1750 ptg000031l:1337519-1340319 F1MNN4 8.29e-110 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 25269 FUN_039885 2961 2352 1780 2593 1750 ptg000031l:1337519-1340319 F1MNN4 2.22e-75 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 25270 FUN_039885 2961 2352 1780 2593 1750 ptg000031l:1337519-1340319 F1MNN4 5.95e-35 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 25271 FUN_039885 2961 2352 1780 2593 1750 ptg000031l:1337519-1340319 F1MNN4 1.61e-30 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 25272 FUN_039885 2961 2352 1780 2593 1750 ptg000031l:1337519-1340319 F1MNN4 3.68e-27 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 25273 FUN_039885 2961 2352 1780 2593 1750 ptg000031l:1337519-1340319 F1MNN4 1.08e-24 F-box/WD repeat-containing protein 7 (F-box and WD-40 domain-containing protein 7) Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; lung development [GO:0030324]; negative regulation of gene expression [GO:0010629]; negative regulation of osteoclast development [GO:2001205]; negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903026]; Notch signaling pathway [GO:0007219]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway [GO:1903378]; positive regulation of proteasomal protein catabolic process [GO:1901800]; positive regulation of protein targeting to mitochondrion [GO:1903955]; positive regulation of ubiquitin-dependent protein catabolic process [GO:2000060]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein K63-linked ubiquitination [GO:0070534]; protein stabilization [GO:0050821]; regulation of autophagy of mitochondrion [GO:1903146]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of circadian rhythm [GO:0042752]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; sister chromatid cohesion [GO:0007062]; vasculogenesis [GO:0001570] GO:0001570; GO:0005654; GO:0005694; GO:0005730; GO:0005739; GO:0005783; GO:0006281; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0006974; GO:0007062; GO:0007219; GO:0010629; GO:0019005; GO:0030126; GO:0030324; GO:0030332; GO:0031146; GO:0031625; GO:0031648; GO:0042752; GO:0042802; GO:0045741; GO:0048471; GO:0050816; GO:0050821; GO:0051443; GO:0070374; GO:0070534; GO:0090049; GO:0097027; GO:1901800; GO:1903026; GO:1903146; GO:1903378; GO:1903955; GO:1990452; GO:1990756; GO:2000060; GO:2001205 25274 FUN_039886 169 107 43 90 42 ptg000031l:1341923-1343828 Q9H8P0 1.81e-24 Polyprenol reductase (EC 1.3.1.94) (3-oxo-5-alpha-steroid 4-dehydrogenase 3) (EC 1.3.1.22) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3) Homo sapiens (Human) androgen biosynthetic process [GO:0006702]; dolichol biosynthetic process [GO:0019408]; dolichol metabolic process [GO:0019348]; dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; dolichyl diphosphate biosynthetic process [GO:0006489]; polyprenol catabolic process [GO:0016095] GO:0003865; GO:0005783; GO:0005789; GO:0006488; GO:0006489; GO:0006702; GO:0016095; GO:0016628; GO:0019348; GO:0019408; GO:0047751; GO:0102389 25275 FUN_039887 2167 2660 1772 1756 1396 NA NA NA NA NA NA NA 25276 FUN_039888 3 0 30 4 70 NA NA NA NA NA NA NA 25277 FUN_039889 1417 2687 922 1464 1981 NA NA NA NA NA NA NA 25278 FUN_022485 58786 122839 37399 89351 40362 NA NA NA NA NA NA NA 25279 FUN_022487 4143 1656 289 2338 1095 ptg000016l:9537144-9539218 A6H779 5.87e-26 F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) Bos taurus (Bovine) negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of inflammatory response [GO:0050727]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005516; GO:0010506; GO:0014066; GO:0016020; GO:0016567; GO:0019005; GO:0031146; GO:0050727; GO:1900226; GO:1990756 25280 FUN_022487 4143 1656 289 2338 1095 ptg000016l:9537144-9539218 A6H779 2.46e-21 F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) Bos taurus (Bovine) negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; protein ubiquitination [GO:0016567]; regulation of autophagy [GO:0010506]; regulation of inflammatory response [GO:0050727]; regulation of phosphatidylinositol 3-kinase signaling [GO:0014066]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005516; GO:0010506; GO:0014066; GO:0016020; GO:0016567; GO:0019005; GO:0031146; GO:0050727; GO:1900226; GO:1990756 25281 FUN_022480 4834 3364 3046 2574 2063 NA NA NA NA NA NA NA 25282 FUN_015520 31 28 5 15 24 NA NA NA NA NA NA NA 25283 FUN_022482 3025 2968 1318 2329 2520 NA NA NA NA NA NA NA 25284 FUN_022488 178 199 182 229 215 NA NA NA NA NA NA NA 25285 FUN_015528 7 8 9 0 11 NA NA NA NA NA NA NA 25286 FUN_018650 0 21 0 0 0 NA NA NA NA NA NA NA 25287 FUN_018658 88 170 24 60 153 NA NA NA NA NA NA NA 25288 FUN_018659 85 132 51 58 105 ptg000012l:11593837-11597873 Q96AY4 1.83e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25289 FUN_018659 85 132 51 58 105 ptg000012l:11593837-11597873 Q96AY4 4.61e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25290 FUN_018659 85 132 51 58 105 ptg000012l:11593837-11597873 Q96AY4 2.96e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25291 FUN_018659 85 132 51 58 105 ptg000012l:11593837-11597873 Q96AY4 3.08e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25292 FUN_018659 85 132 51 58 105 ptg000012l:11593837-11597873 Q96AY4 6.5e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25293 FUN_018659 85 132 51 58 105 ptg000012l:11593837-11597873 Q96AY4 2.68e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25294 FUN_007267 26 0 26 0 21 ptg000002l:724628-728269 Q6LAF1 6.91e-45 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 25295 FUN_018165 13 0 17 0 0 NA NA NA NA NA NA NA 25296 FUN_028172 3244 3712 1310 2751 2139 NA NA NA NA NA NA NA 25297 FUN_025276 67 0 45 84 0 NA NA NA NA NA NA NA 25298 FUN_025274 0 0 13 84 0 NA NA NA NA NA NA NA 25299 FUN_025273 11 0 0 6 0 NA NA NA NA NA NA NA 25300 FUN_025270 95 0 0 0 0 NA NA NA NA NA NA NA 25301 FUN_028176 0 0 2 0 10 NA NA NA NA NA NA NA 25302 FUN_028177 0 0 0 0 11 NA NA NA NA NA NA NA 25303 FUN_040254 54 20 211 119 127 ptg000031l:5949669-5956800 Q15818 3.8e-25 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 25304 FUN_028174 1926 1480 674 966 914 ptg000021l:16499246-16513135 P79384 5.43e-33 Propionyl-CoA carboxylase beta chain, mitochondrial (PCCase subunit beta) (EC 6.4.1.3) (Propanoyl-CoA:carbon dioxide ligase subunit beta) Sus scrofa (Pig) short-chain fatty acid catabolic process [GO:0019626] GO:0004658; GO:0005524; GO:0005739; GO:0005759; GO:0019626 25305 FUN_019520 31 6 8 29 12 NA NA NA NA NA NA NA 25306 FUN_019523 15 0 5 5 42 NA NA NA NA NA NA NA 25307 FUN_019522 14 0 0 21 34 NA NA NA NA NA NA NA 25308 FUN_044096 65 130 98 76 259 NA NA NA NA NA NA NA 25309 FUN_019527 0 0 0 0 16 NA NA NA NA NA NA NA 25310 FUN_019529 20 34 0 15 139 NA NA NA NA NA NA NA 25311 FUN_044099 4 1 17 2 114 NA NA NA NA NA NA NA 25312 FUN_044098 3 0 5 3 50 NA NA NA NA NA NA NA 25313 FUN_011016 183 0 76 0 0 NA NA NA NA NA NA NA 25314 FUN_030632 3 29 0 37 26 NA NA NA NA NA NA NA 25315 FUN_039718 0 0 27 0 0 NA NA NA NA NA NA NA 25316 FUN_039719 0 0 120 0 0 NA NA NA NA NA NA NA 25317 FUN_013912 33 10 16 0 31 NA NA NA NA NA NA NA 25318 FUN_039714 0 0 0 0 16 NA NA NA NA NA NA NA 25319 FUN_039715 5 0 0 0 20 NA NA NA NA NA NA NA 25320 FUN_039716 0 0 3 0 14 NA NA NA NA NA NA NA 25321 FUN_039717 0 48 17 83 17 NA NA NA NA NA NA NA 25322 FUN_032339 120 400 151 116 160 NA NA NA NA NA NA NA 25323 FUN_032338 94 19 71 81 51 NA NA NA NA NA NA NA 25324 FUN_036779 12 46 70 11 9 NA NA NA NA NA NA NA 25325 FUN_036773 11070 5898 5325 14140 13828 NA NA NA NA NA NA NA 25326 FUN_036772 136 156 42 100 124 NA NA NA NA NA NA NA 25327 FUN_036777 65 34 120 233 200 NA NA NA NA NA NA NA 25328 FUN_036776 0 0 0 0 10 NA NA NA NA NA NA NA 25329 FUN_006149 29 0 63 6 235 ptg000001l:8460247-8472817 B8V7S0 5.99e-82 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 25330 FUN_006149 29 0 63 6 235 ptg000001l:8460247-8472817 B8V7S0 7.05e-21 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 25331 FUN_030056 1867 690 814 2065 1979 NA NA NA NA NA NA NA 25332 FUN_041384 28 15 0 0 1 ptg000035l:2975741-2977877 P61752 2.36e-25 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 25333 FUN_006143 0 0 5 0 161 NA NA NA NA NA NA NA 25334 FUN_006142 0 0 0 16 58 NA NA NA NA NA NA NA 25335 FUN_032330 0 0 30 0 0 NA NA NA NA NA NA NA 25336 FUN_006145 10027 7314 10356 24216 14801 NA NA NA NA NA NA NA 25337 FUN_031279 5 11 4 8 17 NA NA NA NA NA NA NA 25338 FUN_031278 70 19 14 33 21 NA NA NA NA NA NA NA 25339 FUN_031276 252 205 221 261 462 NA NA NA NA NA NA NA 25340 FUN_031275 1243 841 623 1052 1010 NA NA NA NA NA NA NA 25341 FUN_031274 232 158 95 171 77 ptg000023l:18767101-18768388 Q09470 1.65e-96 Potassium voltage-gated channel subfamily A member 1 (Voltage-gated K(+) channel HuKI) (Voltage-gated potassium channel HBK1) (Voltage-gated potassium channel subunit Kv1.1) Homo sapiens (Human) axon development [GO:0061564]; cell communication by electrical coupling [GO:0010644]; cellular response to magnesium ion [GO:0071286]; cerebral cortex development [GO:0021987]; chemical synaptic transmission [GO:0007268]; corpus callosum development [GO:0022038]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; detection of mechanical stimulus involved in sensory perception of touch [GO:0050976]; hippocampus development [GO:0021766]; magnesium ion homeostasis [GO:0010960]; neuroblast proliferation [GO:0007405]; neuromuscular process [GO:0050905]; neuronal action potential [GO:0019228]; neuronal signal transduction [GO:0023041]; optic nerve development [GO:0021554]; positive regulation of voltage-gated potassium channel activity [GO:1903818]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; protein localization [GO:0008104]; regulation of membrane potential [GO:0042391]; regulation of muscle contraction [GO:0006937]; startle response [GO:0001964] GO:0001964; GO:0005249; GO:0005251; GO:0005267; GO:0005783; GO:0005829; GO:0005886; GO:0006813; GO:0006937; GO:0007268; GO:0007405; GO:0008076; GO:0008104; GO:0009986; GO:0010644; GO:0010960; GO:0015079; GO:0016020; GO:0016324; GO:0019228; GO:0021554; GO:0021766; GO:0021987; GO:0022038; GO:0023041; GO:0030054; GO:0030425; GO:0031410; GO:0033270; GO:0042391; GO:0042734; GO:0043025; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0044305; GO:0045202; GO:0045211; GO:0050905; GO:0050966; GO:0050976; GO:0051260; GO:0061564; GO:0070161; GO:0071286; GO:0071805; GO:0097718; GO:0098978; GO:0099508; GO:1903818; GO:1905030 25342 FUN_031273 309 83 104 439 217 NA NA NA NA NA NA NA 25343 FUN_031272 201 79 20 397 19 NA NA NA NA NA NA NA 25344 FUN_031271 1 0 0 30 0 NA NA NA NA NA NA NA 25345 FUN_031270 22436 26354 10459 18882 7496 NA NA NA NA NA NA NA 25346 FUN_005788 15 0 0 0 0 NA NA NA NA NA NA NA 25347 FUN_005789 0 0 0 0 11 NA NA NA NA NA NA NA 25348 FUN_005781 48 18 0 16 95 NA NA NA NA NA NA NA 25349 FUN_001498 2285 2566 861 2189 487 NA NA NA NA NA NA NA 25350 FUN_001499 41 3 37 0 51 NA NA NA NA NA NA NA 25351 FUN_001490 1546 926 932 2104 693 NA NA NA NA NA NA NA 25352 FUN_001492 17 29 25 168 102 NA NA NA NA NA NA NA 25353 FUN_001493 89 256 0 443 323 NA NA NA NA NA NA NA 25354 FUN_001494 104 232 114 293 53 NA NA NA NA NA NA NA 25355 FUN_001496 75 0 28 0 0 NA NA NA NA NA NA NA 25356 FUN_001497 28208 25112 15636 35750 22644 NA NA NA NA NA NA NA 25357 FUN_033659 39 103 94 108 279 NA NA NA NA NA NA NA 25358 FUN_033658 3 0 11 1 78 NA NA NA NA NA NA NA 25359 FUN_033651 44 0 0 9 351 NA NA NA NA NA NA NA 25360 FUN_033650 12 1 3 0 26 NA NA NA NA NA NA NA 25361 FUN_033657 0 1 3 0 8 NA NA NA NA NA NA NA 25362 FUN_033656 2 15 11 9 6 NA NA NA NA NA NA NA 25363 FUN_033654 3 0 0 0 8 NA NA NA NA NA NA NA 25364 FUN_004787 954 457 487 1409 1438 NA NA NA NA NA NA NA 25365 FUN_004786 2346 2185 1408 2785 1680 ntLink_8:27000211-27012613 Q4R9A9 6.17e-35 Casein kinase I isoform gamma-1 (CKI-gamma 1) (EC 2.7.11.1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0016055; GO:0106310 25366 FUN_004785 2139 1677 906 1467 715 NA NA NA NA NA NA NA 25367 FUN_004784 834 900 467 1339 564 NA NA NA NA NA NA NA 25368 FUN_004783 8679 19421 5129 11180 3643 NA NA NA NA NA NA NA 25369 FUN_004782 752 842 210 638 112 NA NA NA NA NA NA NA 25370 FUN_004781 156 197 74 290 124 ntLink_8:26956242-26958893 D3ZVM4 1.15e-76 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Rattus norvegicus (Rat) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0016567; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 25371 FUN_004781 156 197 74 290 124 ntLink_8:26956242-26958893 D3ZVM4 8.42e-33 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Rattus norvegicus (Rat) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0016567; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 25372 FUN_004780 52225 41416 22951 47343 41886 ntLink_8:26938540-26952590 Q90705 5.98e-88 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 25373 FUN_004780 52225 41416 22951 47343 41886 ntLink_8:26938540-26952590 Q90705 1.27e-34 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 25374 FUN_004780 52225 41416 22951 47343 41886 ntLink_8:26938540-26952590 Q90705 1.09e-33 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 25375 FUN_004780 52225 41416 22951 47343 41886 ntLink_8:26938540-26952590 Q90705 3.71e-29 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 25376 FUN_004780 52225 41416 22951 47343 41886 ntLink_8:26938540-26952590 Q90705 1.83e-21 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 25377 FUN_004780 52225 41416 22951 47343 41886 ntLink_8:26938540-26952590 Q90705 2.26e-21 Elongation factor 2 (EF-2) Gallus gallus (Chicken) translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006414; GO:0043022; GO:1990904 25378 FUN_004789 0 0 0 17 0 NA NA NA NA NA NA NA 25379 FUN_004788 7 13 6 17 0 NA NA NA NA NA NA NA 25380 FUN_042308 149 51 94 0 70 NA NA NA NA NA NA NA 25381 FUN_044206 5 5 20 3 133 NA NA NA NA NA NA NA 25382 FUN_044248 1 0 3 3 7 NA NA NA NA NA NA NA 25383 FUN_044249 2 1 3 12 16 NA NA NA NA NA NA NA 25384 FUN_022112 712 631 591 742 485 NA NA NA NA NA NA NA 25385 FUN_044242 5 2 14 4 98 NA NA NA NA NA NA NA 25386 FUN_044243 3 0 4 1 29 NA NA NA NA NA NA NA 25387 FUN_044240 23 103 20 55 174 NA NA NA NA NA NA NA 25388 FUN_035340 1355 1586 1120 1670 1569 ptg000025l:6539995-6541595 Q28E28 3.05e-27 Protein phosphatase 1 regulatory subunit 3B Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) glycogen metabolic process [GO:0005977]; regulation of glycogen catabolic process [GO:0005981] GO:0000164; GO:0005977; GO:0005981; GO:0019888 25389 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 3.07e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25390 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 4.57e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25391 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 2.12e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25392 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 3.73e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25393 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 1.27e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25394 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 1.87e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25395 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 5.44e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25396 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 2.5e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25397 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 7.01e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25398 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 7.43e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25399 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 3.71e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25400 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 9.18e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25401 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 3.52e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25402 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 6.82e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25403 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 1.42e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25404 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 7.33e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25405 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 2.54e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25406 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 1.3e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25407 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 4.5e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25408 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 3.02e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25409 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 5.1e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25410 FUN_000345 2056 1410 943 2190 1944 ntLink_6:1777812-1792467 Q96AY4 7.51e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25411 FUN_044246 285 43 12 120 79 NA NA NA NA NA NA NA 25412 FUN_041798 281 148 161 395 424 NA NA NA NA NA NA NA 25413 FUN_003603 0 0 43 0 0 NA NA NA NA NA NA NA 25414 FUN_035346 183 24 0 112 56 NA NA NA NA NA NA NA 25415 FUN_034388 3804 3358 1639 2541 1138 NA NA NA NA NA NA NA 25416 FUN_044244 3 0 11 1 83 NA NA NA NA NA NA NA 25417 FUN_018350 1003 128 801 431 574 NA NA NA NA NA NA NA 25418 FUN_034382 3282 3699 2940 5102 3732 ptg000024l:8283637-8287933 Q9JHC9 1.29e-28 ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS-related factor) Mus musculus (Mouse) cell differentiation [GO:0030154]; negative regulation of DNA-templated transcription [GO:0045892]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000981; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0006357; GO:0016604; GO:0030154; GO:0043565; GO:0045892; GO:0045893; GO:1990837 25419 FUN_044245 93 24 34 79 60 NA NA NA NA NA NA NA 25420 FUN_034384 12 109 44 71 68 NA NA NA NA NA NA NA 25421 FUN_012715 28 0 11 20 35 NA NA NA NA NA NA NA 25422 FUN_012714 16 0 0 0 0 NA NA NA NA NA NA NA 25423 FUN_012713 0 2 0 2 6 NA NA NA NA NA NA NA 25424 FUN_012712 8 12 10 16 3 NA NA NA NA NA NA NA 25425 FUN_012711 45 95 11 100 19 NA NA NA NA NA NA NA 25426 FUN_012710 517 236 144 748 439 NA NA NA NA NA NA NA 25427 FUN_044202 5 10 10 16 36 NA NA NA NA NA NA NA 25428 FUN_012719 23 2 6 14 26 NA NA NA NA NA NA NA 25429 FUN_016407 219 838 239 597 458 ptg000011l:2783475-2784405 Q4R6P2 4.81e-69 RWD domain-containing protein 2A Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 25430 FUN_006924 117 29 36 99 88 NA NA NA NA NA NA NA 25431 FUN_006927 134 145 212 130 129 NA NA NA NA NA NA NA 25432 FUN_006926 99 0 56 77 43 NA NA NA NA NA NA NA 25433 FUN_016403 519 7 365 432 284 NA NA NA NA NA NA NA 25434 FUN_016402 3344 1691 2185 3531 2832 ptg000011l:2712259-2748568 Q9Z1T6 2e-25 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) (p235) Mus musculus (Mouse) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0000285; GO:0004674; GO:0005524; GO:0005829; GO:0005911; GO:0006612; GO:0008270; GO:0010008; GO:0012506; GO:0016301; GO:0016308; GO:0019065; GO:0019886; GO:0030593; GO:0030670; GO:0031410; GO:0031901; GO:0031902; GO:0032288; GO:0032438; GO:0034504; GO:0035556; GO:0036289; GO:0042147; GO:0045121; GO:0048471; GO:0052810; GO:0090382; GO:0090385; GO:0106310; GO:1903100; GO:1903426; GO:1904562; GO:2000785 25435 FUN_016402 3344 1691 2185 3531 2832 ptg000011l:2712259-2748568 Q9Z1T6 5.28e-24 1-phosphatidylinositol 3-phosphate 5-kinase (Phosphatidylinositol 3-phosphate 5-kinase) (EC 2.7.1.150) (FYVE finger-containing phosphoinositide kinase) (PIKfyve) (Phosphatidylinositol 3-phosphate 5-kinase type III) (PIPkin-III) (Type III PIP kinase) (Serine-protein kinase PIKFYVE) (EC 2.7.11.1) (p235) Mus musculus (Mouse) 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process [GO:1903100]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; intracellular signal transduction [GO:0035556]; melanosome organization [GO:0032438]; myelin assembly [GO:0032288]; neutrophil chemotaxis [GO:0030593]; peptidyl-serine autophosphorylation [GO:0036289]; phagosome maturation [GO:0090382]; phagosome-lysosome fusion [GO:0090385]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; protein localization to nucleus [GO:0034504]; protein targeting to membrane [GO:0006612]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; regulation of autophagosome assembly [GO:2000785]; regulation of reactive oxygen species biosynthetic process [GO:1903426]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0000285; GO:0004674; GO:0005524; GO:0005829; GO:0005911; GO:0006612; GO:0008270; GO:0010008; GO:0012506; GO:0016301; GO:0016308; GO:0019065; GO:0019886; GO:0030593; GO:0030670; GO:0031410; GO:0031901; GO:0031902; GO:0032288; GO:0032438; GO:0034504; GO:0035556; GO:0036289; GO:0042147; GO:0045121; GO:0048471; GO:0052810; GO:0090382; GO:0090385; GO:0106310; GO:1903100; GO:1903426; GO:1904562; GO:2000785 25436 FUN_016401 615 424 324 536 267 NA NA NA NA NA NA NA 25437 FUN_016400 4377 1776 1834 2483 2269 NA NA NA NA NA NA NA 25438 FUN_006929 7191 6578 4265 4775 3563 NA NA NA NA NA NA NA 25439 FUN_006928 8 38 37 11 0 NA NA NA NA NA NA NA 25440 FUN_016409 2062 2046 1431 1254 1065 NA NA NA NA NA NA NA 25441 FUN_013557 2324 1941 1079 1950 1546 NA NA NA NA NA NA NA 25442 FUN_040896 5 1 7 0 1 NA NA NA NA NA NA NA 25443 FUN_040891 0 0 17 0 47 NA NA NA NA NA NA NA 25444 FUN_044203 42 147 70 127 299 NA NA NA NA NA NA NA 25445 FUN_035161 0 113 157 0 106 NA NA NA NA NA NA NA 25446 FUN_035160 321 303 259 467 197 NA NA NA NA NA NA NA 25447 FUN_035167 0 37 77 260 76 NA NA NA NA NA NA NA 25448 FUN_035166 6511 4431 5939 4106 4435 NA NA NA NA NA NA NA 25449 FUN_035165 17 0 31 0 0 NA NA NA NA NA NA NA 25450 FUN_035169 2136 1784 791 2206 1568 ptg000025l:4713833-4717123 Q9JK84 2.27e-61 Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6A) Mus musculus (Mouse) cell division [GO:0051301]; centrosome cycle [GO:0007098]; establishment or maintenance of cell polarity [GO:0007163]; regulation of cellular localization [GO:0060341] GO:0005080; GO:0005634; GO:0005923; GO:0005938; GO:0007098; GO:0007163; GO:0016324; GO:0032991; GO:0051301; GO:0060341 25451 FUN_035168 2109 1328 539 1570 732 ptg000025l:4709355-4711477 Q9BZ19 1.63e-37 Ankyrin repeat domain-containing protein 60 Homo sapiens (Human) NA NA 25452 FUN_033934 84 0 21 23 62 ptg000024l:2851201-2852617 Q9IB89 1.97e-92 Zinc finger protein ZIC 5 (XZic5) (XlZic5) (Zinc finger protein of the cerebellum 5) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 25453 FUN_033935 0 0 4 8 0 ptg000024l:2867998-2872910 A0JC51 2.81e-79 Zinc finger protein ZIC 4 (XlZic4) (Zinc finger protein of the cerebellum 4) Xenopus laevis (African clawed frog) nervous system development [GO:0007399]; neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0007399; GO:0014029; GO:0046872 25454 FUN_039996 0 0 7 0 17 NA NA NA NA NA NA NA 25455 FUN_043272 68 17 28 59 71 NA NA NA NA NA NA NA 25456 FUN_043273 121 260 75 115 93 NA NA NA NA NA NA NA 25457 FUN_043270 42 5 0 24 23 NA NA NA NA NA NA NA 25458 FUN_043271 205 58 40 41 76 NA NA NA NA NA NA NA 25459 FUN_043276 0 19 0 0 203 NA NA NA NA NA NA NA 25460 FUN_043274 213 146 165 190 248 NA NA NA NA NA NA NA 25461 FUN_043275 13 0 0 8 61 NA NA NA NA NA NA NA 25462 FUN_043278 95 191 118 142 73 NA NA NA NA NA NA NA 25463 FUN_033931 201 94 71 125 173 NA NA NA NA NA NA NA 25464 FUN_001921 23 35 25 334 55 ntLink_6:17838529-17853417 Q8NHM4 9.65e-28 Putative trypsin-6 (EC 3.4.21.4) (Serine protease 3 pseudogene 2) (Trypsinogen C) Homo sapiens (Human) endothelial cell migration [GO:0043542]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0043542; GO:0046872 25465 FUN_028767 55 80 35 26 59 ptg000022l:3670596-3673761 Q96AY4 1.18e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25466 FUN_028767 55 80 35 26 59 ptg000022l:3670596-3673761 Q96AY4 1.89e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25467 FUN_028767 55 80 35 26 59 ptg000022l:3670596-3673761 Q96AY4 3.22e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25468 FUN_028767 55 80 35 26 59 ptg000022l:3670596-3673761 Q96AY4 6.2e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25469 FUN_013047 0 0 0 0 13 NA NA NA NA NA NA NA 25470 FUN_013040 0 0 12 0 20 NA NA NA NA NA NA NA 25471 FUN_028761 0 15 18 1 25 NA NA NA NA NA NA NA 25472 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 3.02e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25473 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 2.4e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25474 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 9.96e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25475 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 2.4e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25476 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 4.21e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25477 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 1.71e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25478 FUN_028760 12 26 62 17 18 ptg000022l:3614713-3623954 Q96AY4 9.66e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25479 FUN_028769 2 0 12 4 9 NA NA NA NA NA NA NA 25480 FUN_042635 60 74 40 78 72 NA NA NA NA NA NA NA 25481 FUN_042634 7513 8288 4380 8380 6779 NA NA NA NA NA NA NA 25482 FUN_042637 707 405 485 1142 1270 NA NA NA NA NA NA NA 25483 FUN_042636 626 402 771 496 355 NA NA NA NA NA NA NA 25484 FUN_042631 1896 1332 1050 1149 1148 NA NA NA NA NA NA NA 25485 FUN_042630 2525 1518 1244 2728 1941 NA NA NA NA NA NA NA 25486 FUN_042633 4275 3050 2250 4822 3648 ptg000039l:597544-608760 O00712 1.75e-84 Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) Homo sapiens (Human) anterior commissure morphogenesis [GO:0021960]; brain development [GO:0007420]; cell differentiation involved in salivary gland development [GO:0060689]; chondrocyte differentiation [GO:0002062]; club cell differentiation [GO:0060486]; commissural neuron axon guidance [GO:0071679]; DNA replication [GO:0006260]; glandular epithelial cell differentiation [GO:0002067]; glial cell differentiation [GO:0010001]; hindbrain development [GO:0030902]; lung ciliated cell differentiation [GO:0061141]; negative regulation of DNA binding [GO:0043392]; negative regulation of epithelial cell proliferation involved in lung morphogenesis [GO:2000795]; negative regulation of mesenchymal cell proliferation involved in lung development [GO:2000791]; negative regulation of miRNA transcription [GO:1902894]; negative regulation of stem cell proliferation [GO:2000647]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; principal sensory nucleus of trigeminal nerve development [GO:0021740]; regulation of transcription by RNA polymerase II [GO:0006357]; response to bacterium [GO:0009617]; salivary gland cavitation [GO:0060662]; stem cell proliferation [GO:0072089]; type I pneumocyte differentiation [GO:0060509]; type II pneumocyte differentiation [GO:0060510] GO:0000122; GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001650; GO:0002062; GO:0002067; GO:0003677; GO:0005634; GO:0005654; GO:0006260; GO:0006357; GO:0007420; GO:0009617; GO:0010001; GO:0021740; GO:0021960; GO:0030902; GO:0043392; GO:0044300; GO:0045893; GO:0045944; GO:0060486; GO:0060509; GO:0060510; GO:0060662; GO:0060689; GO:0061141; GO:0071679; GO:0072089; GO:0140416; GO:1902894; GO:1990837; GO:2000647; GO:2000791; GO:2000795 25487 FUN_042632 384 163 170 259 308 NA NA NA NA NA NA NA 25488 FUN_042639 0 0 25 0 60 NA NA NA NA NA NA NA 25489 FUN_042638 207 238 339 290 297 NA NA NA NA NA NA NA 25490 FUN_017304 192 0 70 27 0 NA NA NA NA NA NA NA 25491 FUN_002121 69 43 51 26 51 NA NA NA NA NA NA NA 25492 FUN_009316 0 0 0 0 34 ptg000004l:5218085-5219952 Q91X17 2.55e-21 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 25493 FUN_009315 25 6 28 3 248 NA NA NA NA NA NA NA 25494 FUN_009312 445 188 125 197 350 NA NA NA NA NA NA NA 25495 FUN_002127 37 0 20 0 26 NA NA NA NA NA NA NA 25496 FUN_009319 62 29 73 54 439 NA NA NA NA NA NA NA 25497 FUN_009318 44 15 0 17 56 NA NA NA NA NA NA NA 25498 FUN_026732 177 310 88 249 93 ptg000020l:12907247-12908882 Q6ZSS7 6.22e-68 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Homo sapiens (Human) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 25499 FUN_004700 2023 1439 593 1483 544 NA NA NA NA NA NA NA 25500 FUN_026733 136 165 20 31 96 ptg000020l:12912227-12913820 A1DWM3 2.35e-65 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 25501 FUN_020029 0 0 0 0 23 NA NA NA NA NA NA NA 25502 FUN_014996 978 396 442 670 640 ptg000009l:5138367-5166733 P36633 3.55e-178 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Rattus norvegicus (Rat) amiloride transport [GO:0015898]; amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0015898; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097159; GO:0097185 25503 FUN_026731 114 29 11 14 50 NA NA NA NA NA NA NA 25504 FUN_029014 1645 681 1194 1873 2223 NA NA NA NA NA NA NA 25505 FUN_014994 2503 2164 1206 1980 1468 NA NA NA NA NA NA NA 25506 FUN_040709 152157 87183 89887 73175 55518 ptg000031l:12255282-12256961 P47236 5.05e-43 Paired box protein Pax-1 Gallus gallus (Chicken) anatomical structure development [GO:0048856]; regulation of transcription by RNA polymerase II [GO:0006357]; sclerotome development [GO:0061056] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0048856; GO:0061056 25507 FUN_040708 6193 5039 3603 5058 3894 ptg000031l:12251172-12252524 P47236 5.85e-46 Paired box protein Pax-1 Gallus gallus (Chicken) anatomical structure development [GO:0048856]; regulation of transcription by RNA polymerase II [GO:0006357]; sclerotome development [GO:0061056] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0048856; GO:0061056 25508 FUN_040707 44 95 58 417 41 NA NA NA NA NA NA NA 25509 FUN_010026 11 0 11 12 4 NA NA NA NA NA NA NA 25510 FUN_040702 0 0 0 0 18 NA NA NA NA NA NA NA 25511 FUN_010021 18 0 0 0 0 NA NA NA NA NA NA NA 25512 FUN_040700 40 44 40 28 111 ptg000031l:12102328-12105230 Q7L622 1.27e-46 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Homo sapiens (Human) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005794; GO:0005829; GO:0006915; GO:0043231; GO:0046872 25513 FUN_012872 1226 1317 919 1127 1059 NA NA NA NA NA NA NA 25514 FUN_012870 11 64 33 28 28 NA NA NA NA NA NA NA 25515 FUN_012871 1236 1686 861 1693 2559 NA NA NA NA NA NA NA 25516 FUN_012875 2440 2469 1159 2031 1080 NA NA NA NA NA NA NA 25517 FUN_029011 1948 1719 993 2866 2422 NA NA NA NA NA NA NA 25518 FUN_011990 839 837 623 682 599 ptg000008l:3888593-3894919 Q9CXC3 1.32e-21 Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) Mus musculus (Mouse) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] GO:0000002; GO:0005739; GO:0006264; GO:0008297; GO:0043504 25519 FUN_011991 1765 1757 1418 1769 815 NA NA NA NA NA NA NA 25520 FUN_011992 2461 3517 2057 2463 1282 NA NA NA NA NA NA NA 25521 FUN_011993 4341 4593 2303 3343 1410 NA NA NA NA NA NA NA 25522 FUN_011994 32 26 14 39 27 NA NA NA NA NA NA NA 25523 FUN_011995 26 9 0 0 0 NA NA NA NA NA NA NA 25524 FUN_011996 331 108 58 97 40 NA NA NA NA NA NA NA 25525 FUN_011997 366 261 195 565 377 ptg000008l:3947255-3948383 Q4QRH7 4.45e-86 Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16) Danio rerio (Zebrafish) (Brachydanio rerio) peroxisome organization [GO:0007031] GO:0005778; GO:0007031 25526 FUN_011998 5634 6473 3240 5624 2920 ptg000008l:3950139-3951112 A5PK71 5.98e-114 Parkin coregulated gene protein Bos taurus (Bovine) negative regulation of cell death [GO:0060548]; protein localization [GO:0008104]; spermatid development [GO:0007286] GO:0001664; GO:0002177; GO:0003779; GO:0005829; GO:0005879; GO:0007286; GO:0008104; GO:0030544; GO:0031625; GO:0031982; GO:0043005; GO:0043014; GO:0044297; GO:0048487; GO:0051087; GO:0051879; GO:0060548; GO:0097225 25527 FUN_011999 713 955 473 765 583 NA NA NA NA NA NA NA 25528 FUN_009865 0 13 2 17 0 NA NA NA NA NA NA NA 25529 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 2.68e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25530 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 4.57e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25531 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 2.29e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25532 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 1.25e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25533 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 1.15e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25534 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 5.36e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25535 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 5.5e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25536 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 3.53e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25537 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 2.08e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25538 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 2.26e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25539 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 3.88e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25540 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 2.82e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25541 FUN_009864 0 64 133 119 0 ptg000004l:12784855-12789368 Q96AY4 5.59e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25542 FUN_009866 228 80 76 89 168 NA NA NA NA NA NA NA 25543 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 1.99e-28 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25544 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 6.22e-28 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25545 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 7e-28 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25546 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 7e-28 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25547 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 8.08e-28 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25548 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 1.54e-25 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25549 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 6.15e-25 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25550 FUN_009861 628 218 349 428 227 ptg000004l:12674327-12680242 Q95218 2.65e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 25551 FUN_029018 816 373 416 971 817 NA NA NA NA NA NA NA 25552 FUN_009863 16 8 34 19 91 ptg000004l:12763413-12764877 P14381 4.32e-103 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 25553 FUN_009862 1885 1971 638 1881 963 NA NA NA NA NA NA NA 25554 FUN_031318 27 34 18 0 29 NA NA NA NA NA NA NA 25555 FUN_029019 85 74 39 104 112 NA NA NA NA NA NA NA 25556 FUN_009869 141 275 147 0 0 ptg000004l:12866066-12869218 Q96AY4 2.45e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25557 FUN_009869 141 275 147 0 0 ptg000004l:12866066-12869218 Q96AY4 2.65e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25558 FUN_009869 141 275 147 0 0 ptg000004l:12866066-12869218 Q96AY4 3.22e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25559 FUN_009869 141 275 147 0 0 ptg000004l:12866066-12869218 Q96AY4 5.42e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25560 FUN_009869 141 275 147 0 0 ptg000004l:12866066-12869218 Q96AY4 1.44e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25561 FUN_009869 141 275 147 0 0 ptg000004l:12866066-12869218 Q96AY4 1.78e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25562 FUN_009868 0 15 7 22 0 ptg000004l:12865615-12865948 Q8VDU0 6.63e-25 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 25563 FUN_008198 331 241 312 436 493 NA NA NA NA NA NA NA 25564 FUN_008199 43 0 0 0 31 NA NA NA NA NA NA NA 25565 FUN_008196 424 1125 490 843 781 NA NA NA NA NA NA NA 25566 FUN_008194 42510 31916 20857 22209 9355 NA NA NA NA NA NA NA 25567 FUN_008195 71 229 99 147 47 NA NA NA NA NA NA NA 25568 FUN_008192 2560 1600 958 1513 719 NA NA NA NA NA NA NA 25569 FUN_008193 11972 10799 5852 8368 4361 NA NA NA NA NA NA NA 25570 FUN_008190 907 543 495 808 724 NA NA NA NA NA NA NA 25571 FUN_008191 208 242 144 437 150 NA NA NA NA NA NA NA 25572 FUN_032243 1610 1026 801 1912 2101 ptg000023l:30097439-30103404 Q2VLG6 2.67e-27 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0006953; GO:0009897 25573 FUN_032243 1610 1026 801 1912 2101 ptg000023l:30097439-30103404 Q2VLG6 5.3e-26 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0006953; GO:0009897 25574 FUN_032243 1610 1026 801 1912 2101 ptg000023l:30097439-30103404 Q2VLG6 6.06e-21 Scavenger receptor cysteine-rich type 1 protein M130 (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)] Canis lupus familiaris (Dog) (Canis familiaris) acute-phase response [GO:0006953] GO:0005044; GO:0005576; GO:0006953; GO:0009897 25575 FUN_032242 185 0 13 185 82 ptg000023l:30089337-30095248 Q5RFW0 5.23e-30 Scavenger receptor class A member 5 Danio rerio (Zebrafish) (Brachydanio rerio) cellular iron ion homeostasis [GO:0006879]; endocytosis [GO:0006897]; iron ion transmembrane transport [GO:0034755]; protein homotrimerization [GO:0070207] GO:0005044; GO:0005886; GO:0006879; GO:0006897; GO:0009897; GO:0034755; GO:0070207; GO:0070287 25576 FUN_032241 930 1570 786 975 1085 NA NA NA NA NA NA NA 25577 FUN_032240 2278 1921 2187 2306 2964 ptg000023l:30065460-30070746 P51029 3.55e-27 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 25578 FUN_032240 2278 1921 2187 2306 2964 ptg000023l:30065460-30070746 P51029 1.73e-25 Protein Wnt-8b Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; commissural neuron axon guidance [GO:0071679]; embryonic pattern specification [GO:0009880]; eye development [GO:0001654]; eye field cell fate commitment involved in camera-type eye formation [GO:0060898]; forebrain development [GO:0030900]; forebrain neuron differentiation [GO:0021879]; hypothalamus development [GO:0021854]; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway [GO:0022002]; neuron differentiation [GO:0030182]; otic placode formation [GO:0043049]; sensory epithelium regeneration [GO:0070654] GO:0001654; GO:0005109; GO:0005125; GO:0005615; GO:0009880; GO:0021854; GO:0021879; GO:0022002; GO:0030182; GO:0030900; GO:0043049; GO:0045165; GO:0060070; GO:0060898; GO:0070654; GO:0071679 25579 FUN_032247 2048 1450 1067 1851 1676 NA NA NA NA NA NA NA 25580 FUN_032246 6522 5996 4324 8464 6182 NA NA NA NA NA NA NA 25581 FUN_029968 0 21 0 0 0 NA NA NA NA NA NA NA 25582 FUN_029966 0 0 0 0 17 NA NA NA NA NA NA NA 25583 FUN_029963 0 0 0 7 6 NA NA NA NA NA NA NA 25584 FUN_029961 0 0 0 0 11 NA NA NA NA NA NA NA 25585 FUN_004623 154 37 163 133 317 NA NA NA NA NA NA NA 25586 FUN_031311 197 178 237 208 265 NA NA NA NA NA NA NA 25587 FUN_018482 77 56 104 106 135 NA NA NA NA NA NA NA 25588 FUN_011374 19 0 0 0 0 NA NA NA NA NA NA NA 25589 FUN_011377 9 13 0 0 8 NA NA NA NA NA NA NA 25590 FUN_011371 0 0 0 18 0 NA NA NA NA NA NA NA 25591 FUN_011372 17 0 13 0 9 NA NA NA NA NA NA NA 25592 FUN_011373 12 57 18 111 111 NA NA NA NA NA NA NA 25593 FUN_033063 23 0 12 12 27 NA NA NA NA NA NA NA 25594 FUN_008738 0 36 0 29 0 NA NA NA NA NA NA NA 25595 FUN_008739 0 0 0 42 0 NA NA NA NA NA NA NA 25596 FUN_008732 14 0 0 11 0 NA NA NA NA NA NA NA 25597 FUN_008733 201 223 37 17 11 NA NA NA NA NA NA NA 25598 FUN_008730 234 181 268 341 0 ptg000002l:14909607-14923669 Q80TR8 2.66e-24 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 25599 FUN_008731 57 69 63 88 0 NA NA NA NA NA NA NA 25600 FUN_008736 0 6 0 6 0 NA NA NA NA NA NA NA 25601 FUN_008737 1021 712 120 2273 82 NA NA NA NA NA NA NA 25602 FUN_008734 137 0 0 5 0 NA NA NA NA NA NA NA 25603 FUN_008735 1620 766 374 1205 596 ptg000002l:14955535-14986317 Q80TR8 1.26e-25 DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) Mus musculus (Mouse) B cell differentiation [GO:0030183]; cell competition in a multicellular organism [GO:0035212]; chromatin organization [GO:0006325]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphorylation [GO:0016310]; post-translational protein modification [GO:0043687]; protein ubiquitination [GO:0016567]; V(D)J recombination [GO:0033151] GO:0000122; GO:0001650; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006325; GO:0008180; GO:0016310; GO:0016567; GO:0030183; GO:0030331; GO:0033151; GO:0035212; GO:0043687; GO:0080008; GO:0106310; GO:1990244 25604 FUN_014829 0 0 0 0 18 NA NA NA NA NA NA NA 25605 FUN_000501 536 147 208 388 134 NA NA NA NA NA NA NA 25606 FUN_014822 0 0 0 0 7 ptg000009l:3452313-3453601 Q6UXI7 3.49e-23 Vitrin Homo sapiens (Human) extracellular matrix organization [GO:0030198]; positive regulation of cell-substrate adhesion [GO:0010811]; spinal cord development [GO:0021510] GO:0005539; GO:0005576; GO:0005614; GO:0010811; GO:0021510; GO:0030198; GO:0062023 25607 FUN_014821 0 0 0 18 23 NA NA NA NA NA NA NA 25608 FUN_014826 24 0 23 68 166 ptg000009l:3478356-3495115 Q95LI2 9.13e-22 Vitrin Bos taurus (Bovine) spinal cord development [GO:0021510] GO:0005576; GO:0021510 25609 FUN_013834 0 0 0 0 24 NA NA NA NA NA NA NA 25610 FUN_013836 0 0 0 19 0 NA NA NA NA NA NA NA 25611 FUN_013830 37 45 2 8 29 NA NA NA NA NA NA NA 25612 FUN_013833 147 20 91 37 137 NA NA NA NA NA NA NA 25613 FUN_013839 0 0 0 0 158 NA NA NA NA NA NA NA 25614 FUN_013838 11 0 0 0 123 NA NA NA NA NA NA NA 25615 FUN_023437 354 85 117 370 389 NA NA NA NA NA NA NA 25616 FUN_022013 3075 1838 1366 2427 1821 NA NA NA NA NA NA NA 25617 FUN_017226 26 20 29 23 0 NA NA NA NA NA NA NA 25618 FUN_020955 142 85 90 105 138 NA NA NA NA NA NA NA 25619 FUN_020956 0 0 0 0 38 NA NA NA NA NA NA NA 25620 FUN_039263 0 0 10 0 29 NA NA NA NA NA NA NA 25621 FUN_020950 0 0 19 2 37 NA NA NA NA NA NA NA 25622 FUN_039265 84 218 46 113 103 NA NA NA NA NA NA NA 25623 FUN_039267 887 229 268 692 474 NA NA NA NA NA NA NA 25624 FUN_039268 935 496 405 727 541 NA NA NA NA NA NA NA 25625 FUN_039269 163 27 56 37 56 ptg000028l:98058-101370 Q9I830 1.13e-64 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 25626 FUN_020959 0 0 9 0 21 NA NA NA NA NA NA NA 25627 FUN_037878 248 411 216 315 386 NA NA NA NA NA NA NA 25628 FUN_022011 64 38 3 46 44 NA NA NA NA NA NA NA 25629 FUN_040288 0 46 33 54 79 NA NA NA NA NA NA NA 25630 FUN_010569 67 38 17 38 27 NA NA NA NA NA NA NA 25631 FUN_010563 1455 3980 585 940 2728 NA NA NA NA NA NA NA 25632 FUN_040286 71 172 272 265 15 NA NA NA NA NA NA NA 25633 FUN_040287 3 0 16 0 50 NA NA NA NA NA NA NA 25634 FUN_010564 878 3625 458 599 2314 NA NA NA NA NA NA NA 25635 FUN_040285 10 173 135 192 28 NA NA NA NA NA NA NA 25636 FUN_016739 5 0 6 67 4 NA NA NA NA NA NA NA 25637 FUN_016738 0 18 0 0 0 NA NA NA NA NA NA NA 25638 FUN_017022 2229 1346 1169 2421 1921 ptg000011l:10308550-10336304 Q8BV79 6.44e-126 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 25639 FUN_017022 2229 1346 1169 2421 1921 ptg000011l:10308550-10336304 Q8BV79 1.39e-61 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 25640 FUN_017022 2229 1346 1169 2421 1921 ptg000011l:10308550-10336304 Q8BV79 4.2e-44 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 25641 FUN_017022 2229 1346 1169 2421 1921 ptg000011l:10308550-10336304 Q8BV79 1.08e-24 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1) Mus musculus (Mouse) NA NA 25642 FUN_017020 0 0 0 0 8 NA NA NA NA NA NA NA 25643 FUN_017021 15 0 0 0 0 NA NA NA NA NA NA NA 25644 FUN_040273 8682 7344 4973 6807 2613 NA NA NA NA NA NA NA 25645 FUN_012055 0 0 0 14 21 ptg000008l:4629809-4633467 Q6RI86 2.9e-22 Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Wasabi receptor) Rattus norvegicus (Rat) calcium ion transmembrane import into cytosol [GO:0097553]; calcium ion transmembrane transport [GO:0070588]; calcium ion transport [GO:0006816]; cell surface receptor signaling pathway [GO:0007166]; cellular calcium ion homeostasis [GO:0006874]; cellular response to caffeine [GO:0071313]; cellular response to carbon dioxide [GO:0071244]; cellular response to cold [GO:0070417]; cellular response to heat [GO:0034605]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to organic substance [GO:0071310]; detection of chemical stimulus involved in sensory perception of pain [GO:0050968]; detection of mechanical stimulus involved in sensory perception [GO:0050974]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ion transmembrane transport [GO:0034220]; positive regulation of anion transport [GO:1903793]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of sensory perception of pain [GO:1904058]; protein homotetramerization [GO:0051289]; regulation of blood circulation [GO:1903522]; regulation of neuronal action potential [GO:0098908]; response to cold [GO:0009409]; response to hydrogen peroxide [GO:0042542]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; sensory perception of pain [GO:0019233]; thermoception [GO:0050955]; transmembrane transport [GO:0055085]; urinary bladder smooth muscle contraction [GO:0014832] GO:0005216; GO:0005245; GO:0005262; GO:0005886; GO:0006816; GO:0006874; GO:0007166; GO:0009409; GO:0009410; GO:0010033; GO:0014070; GO:0014832; GO:0015267; GO:0015278; GO:0016324; GO:0019233; GO:0030424; GO:0032421; GO:0034220; GO:0034605; GO:0035774; GO:0042542; GO:0042802; GO:0048265; GO:0050955; GO:0050966; GO:0050968; GO:0050974; GO:0051289; GO:0055085; GO:0070301; GO:0070417; GO:0070588; GO:0071244; GO:0071310; GO:0071313; GO:0097553; GO:0097604; GO:0098908; GO:1903522; GO:1903793; GO:1904058; GO:1990760 25646 FUN_012050 395 378 159 344 278 ptg000008l:4570935-4577127 Q9BUZ4 4.07e-22 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 25647 FUN_012051 4 168 69 177 88 NA NA NA NA NA NA NA 25648 FUN_012052 347 310 198 444 622 NA NA NA NA NA NA NA 25649 FUN_012053 0 0 0 19 0 NA NA NA NA NA NA NA 25650 FUN_015883 24 0 0 13 0 NA NA NA NA NA NA NA 25651 FUN_015884 539 523 362 1472 650 NA NA NA NA NA NA NA 25652 FUN_042850 1195 1205 782 1409 1147 NA NA NA NA NA NA NA 25653 FUN_016733 66 91 71 76 132 NA NA NA NA NA NA NA 25654 FUN_016732 4742 1960 3920 4631 4595 NA NA NA NA NA NA NA 25655 FUN_042855 156 336 180 438 220 NA NA NA NA NA NA NA 25656 FUN_042854 570 641 162 933 277 NA NA NA NA NA NA NA 25657 FUN_042857 2036 1680 1029 1599 1371 ptg000047l:978898-986616 Q5RB58 1.97e-23 Mitotic checkpoint protein BUB3 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cell division [GO:0051301]; chromosome segregation [GO:0007059]; meiotic cell cycle [GO:0051321]; regulation of chromosome segregation [GO:0051983] GO:0000776; GO:0005634; GO:0007059; GO:0051301; GO:0051321; GO:0051983 25658 FUN_016736 196 86 0 236 38 NA NA NA NA NA NA NA 25659 FUN_038288 171 60 77 121 203 NA NA NA NA NA NA NA 25660 FUN_042946 2975 4057 2038 2122 3112 ptg000047l:2205058-2214515 Q12933 1.54e-73 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 25661 FUN_040668 558 0 0 561 141 NA NA NA NA NA NA NA 25662 FUN_010109 5 0 0 0 21 NA NA NA NA NA NA NA 25663 FUN_014593 52 0 0 34 19 NA NA NA NA NA NA NA 25664 FUN_014592 536 524 287 509 350 NA NA NA NA NA NA NA 25665 FUN_014591 196 181 72 241 368 NA NA NA NA NA NA NA 25666 FUN_014590 628 213 399 829 613 ptg000009l:1348412-1349732 Q9R1I1 4.5e-24 Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; inflammatory response [GO:0006954]; leukocyte tethering or rolling [GO:0050901]; N-acetylglucosamine metabolic process [GO:0006044]; positive regulation of leukocyte tethering or rolling [GO:1903238]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006477; GO:0006790; GO:0006954; GO:0050901; GO:1903238 25667 FUN_014597 2350 1844 1379 1535 1440 NA NA NA NA NA NA NA 25668 FUN_003670 55 48 14 150 25 NA NA NA NA NA NA NA 25669 FUN_014595 2829 2083 1606 3179 2289 NA NA NA NA NA NA NA 25670 FUN_014594 1388 958 906 1171 731 NA NA NA NA NA NA NA 25671 FUN_014599 742 365 408 676 605 NA NA NA NA NA NA NA 25672 FUN_014598 1535 856 799 1279 937 NA NA NA NA NA NA NA 25673 FUN_014817 1588 7638 6996 2283 2791 NA NA NA NA NA NA NA 25674 FUN_040664 12 0 0 0 0 NA NA NA NA NA NA NA 25675 FUN_010862 0 0 0 0 13 NA NA NA NA NA NA NA 25676 FUN_040663 1035 1285 746 1154 550 NA NA NA NA NA NA NA 25677 FUN_014044 0 3 5 0 6 NA NA NA NA NA NA NA 25678 FUN_014041 0 0 3 0 45 NA NA NA NA NA NA NA 25679 FUN_014040 0 0 0 0 11 NA NA NA NA NA NA NA 25680 FUN_014049 0 0 0 27 0 NA NA NA NA NA NA NA 25681 FUN_009458 865 1699 556 982 835 NA NA NA NA NA NA NA 25682 FUN_009459 78 27 102 1227 290 ptg000004l:7080667-7185956 P14381 3.44e-94 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 25683 FUN_009459 78 27 102 1227 290 ptg000004l:7080667-7185956 P14381 3.93e-93 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 25684 FUN_009454 30 47 12 43 23 NA NA NA NA NA NA NA 25685 FUN_009455 32 54 48 16 49 NA NA NA NA NA NA NA 25686 FUN_009456 187 206 198 255 348 NA NA NA NA NA NA NA 25687 FUN_009457 823 813 519 507 663 NA NA NA NA NA NA NA 25688 FUN_009450 849 535 294 576 521 NA NA NA NA NA NA NA 25689 FUN_009452 0 12 0 44 94 NA NA NA NA NA NA NA 25690 FUN_009453 13 0 0 12 20 NA NA NA NA NA NA NA 25691 FUN_013689 0 0 0 0 70 NA NA NA NA NA NA NA 25692 FUN_042949 1600 1176 1218 829 1032 ptg000047l:2251447-2263489 Q12933 1.44e-73 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 25693 FUN_004147 1476 23 889 2940 11 NA NA NA NA NA NA NA 25694 FUN_026448 346 44 214 224 255 NA NA NA NA NA NA NA 25695 FUN_026449 91 13 6 36 27 NA NA NA NA NA NA NA 25696 FUN_013910 0 0 18 0 0 NA NA NA NA NA NA NA 25697 FUN_026446 0 0 0 85 0 NA NA NA NA NA NA NA 25698 FUN_026447 0 41 2 112 0 NA NA NA NA NA NA NA 25699 FUN_026440 63 1 109 1 65 NA NA NA NA NA NA NA 25700 FUN_026441 0 0 0 0 35 NA NA NA NA NA NA NA 25701 FUN_026442 59 0 26 0 60 NA NA NA NA NA NA NA 25702 FUN_026443 0 0 0 0 33 NA NA NA NA NA NA NA 25703 FUN_005265 546 781 412 747 387 NA NA NA NA NA NA NA 25704 FUN_022561 1532 905 684 3788 1508 ptg000016l:10558199-10751015 P25291 1.75e-24 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 25705 FUN_022561 1532 905 684 3788 1508 ptg000016l:10558199-10751015 P25291 4.99e-24 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 25706 FUN_022561 1532 905 684 3788 1508 ptg000016l:10558199-10751015 P25291 1.76e-23 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 25707 FUN_022561 1532 905 684 3788 1508 ptg000016l:10558199-10751015 P25291 7.03e-21 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 25708 FUN_022560 0 5 0 17 7 NA NA NA NA NA NA NA 25709 FUN_022567 140 40 39 37 68 NA NA NA NA NA NA NA 25710 FUN_022566 1895 1882 1189 1795 1153 NA NA NA NA NA NA NA 25711 FUN_022565 779 585 405 626 174 NA NA NA NA NA NA NA 25712 FUN_022569 391 263 150 232 378 NA NA NA NA NA NA NA 25713 FUN_022568 385 183 279 717 577 ptg000016l:10789428-10792727 Q9VL06 9.85e-24 E3 ubiquitin-protein ligase Ufd4 (EC 2.3.2.26) (Ubiquitin fusion-degradation 4-like) Drosophila melanogaster (Fruit fly) anatomical structure development [GO:0048856]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0006511; GO:0016607; GO:0032436; GO:0043161; GO:0046872; GO:0048856; GO:0061630; GO:0070373; GO:0070534 25714 FUN_005264 904 282 251 392 777 ntLink_8:33270345-33276778 Q6PCN7 5.75e-24 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 25715 FUN_004141 0 2 0 5 13 NA NA NA NA NA NA NA 25716 FUN_013916 17 0 0 0 33 NA NA NA NA NA NA NA 25717 FUN_005898 25 0 0 8 0 NA NA NA NA NA NA NA 25718 FUN_016003 528 303 228 300 385 NA NA NA NA NA NA NA 25719 FUN_015318 4790 3585 3147 10585 8245 NA NA NA NA NA NA NA 25720 FUN_015319 24 0 19 4 32 NA NA NA NA NA NA NA 25721 FUN_016002 1244 1158 501 976 1060 NA NA NA NA NA NA NA 25722 FUN_015312 17447 18451 8705 16241 10624 NA NA NA NA NA NA NA 25723 FUN_015313 245 174 173 306 360 NA NA NA NA NA NA NA 25724 FUN_015310 21 0 16 49 39 NA NA NA NA NA NA NA 25725 FUN_015311 4705 5384 3341 6277 6489 NA NA NA NA NA NA NA 25726 FUN_015316 1148 623 457 1337 817 NA NA NA NA NA NA NA 25727 FUN_042361 37 0 0 0 0 NA NA NA NA NA NA NA 25728 FUN_015314 1048 2072 1246 1396 625 NA NA NA NA NA NA NA 25729 FUN_015315 16 0 5 15 5 NA NA NA NA NA NA NA 25730 FUN_016000 6153 5663 3337 4637 2714 ptg000010l:322352-335818 Q05481 1.47e-38 Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 25731 FUN_016000 6153 5663 3337 4637 2714 ptg000010l:322352-335818 Q05481 2.48e-21 Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 25732 FUN_016000 6153 5663 3337 4637 2714 ptg000010l:322352-335818 Q05481 7.19e-21 Zinc finger protein 91 (Zinc finger protein HPF7) (Zinc finger protein HTF10) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 25733 FUN_018599 1933 1639 1573 3136 2225 NA NA NA NA NA NA NA 25734 FUN_018598 1710 935 633 1180 922 NA NA NA NA NA NA NA 25735 FUN_018597 156 147 178 140 92 NA NA NA NA NA NA NA 25736 FUN_018596 653 582 361 788 634 NA NA NA NA NA NA NA 25737 FUN_018595 13 11 55 14 5 ptg000012l:10925386-10926763 Q766D5 1.28e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0047238 25738 FUN_018594 15 4 0 19 18 NA NA NA NA NA NA NA 25739 FUN_018593 267 66 343 262 543 NA NA NA NA NA NA NA 25740 FUN_005899 425 447 99 519 362 ptg000001l:5444445-5445601 Q63955 7.44e-87 POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brain-3C) (Brn-3C) (Brn-3.1) Mus musculus (Mouse) axon extension [GO:0048675]; inner ear auditory receptor cell differentiation [GO:0042491]; inner ear development [GO:0048839]; inner ear morphogenesis [GO:0042472]; inner ear receptor cell differentiation [GO:0060113]; neuromuscular process controlling balance [GO:0050885]; neuron apoptotic process [GO:0051402]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; retinal ganglion cell axon guidance [GO:0031290]; sensory perception of sound [GO:0007605]; vestibulocochlear nerve development [GO:0021562] GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0007605; GO:0021562; GO:0031290; GO:0042472; GO:0042491; GO:0043565; GO:0045944; GO:0048675; GO:0048839; GO:0050885; GO:0051402; GO:0060113; GO:1990837 25741 FUN_018591 12 0 0 0 4 NA NA NA NA NA NA NA 25742 FUN_018590 0 0 0 7 4 NA NA NA NA NA NA NA 25743 FUN_004143 3530 1524 2713 3071 1334 ntLink_8:19789071-19792799 P97846 7.59e-33 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 25744 FUN_042364 8 0 0 0 20 NA NA NA NA NA NA NA 25745 FUN_021140 15 30 0 0 17 NA NA NA NA NA NA NA 25746 FUN_021143 15 0 0 0 41 NA NA NA NA NA NA NA 25747 FUN_021145 0 0 0 0 7 NA NA NA NA NA NA NA 25748 FUN_042368 4 3 0 7 7 NA NA NA NA NA NA NA 25749 FUN_028493 6 0 11 34 4 ptg000021l:20662947-20664857 A0A096X8J7 1.53e-173 NA NA NA NA 25750 FUN_004142 868 403 738 1333 543 NA NA NA NA NA NA NA 25751 FUN_017813 4 0 8 11 37 NA NA NA NA NA NA NA 25752 FUN_017811 1243 892 707 1667 1890 NA NA NA NA NA NA NA 25753 FUN_017810 259 252 271 391 458 NA NA NA NA NA NA NA 25754 FUN_017817 406 202 299 377 461 NA NA NA NA NA NA NA 25755 FUN_017816 654 387 556 395 634 ptg000012l:736932-742054 P43446 1.22e-36 Protein Wnt-10a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; neuron differentiation [GO:0030182]; odontogenesis [GO:0042476] GO:0005109; GO:0005125; GO:0005615; GO:0030182; GO:0042476; GO:0045165; GO:0060070 25756 FUN_017815 150 112 118 66 44 ptg000012l:718410-721250 Q93097 3.36e-44 Protein Wnt-2b (Protein Wnt-13) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cellular response to starvation [GO:0009267]; chondrocyte differentiation [GO:0002062]; cornea development in camera-type eye [GO:0061303]; forebrain regionalization [GO:0021871]; hematopoietic stem cell proliferation [GO:0071425]; iris morphogenesis [GO:0061072]; lens development in camera-type eye [GO:0002088]; lung induction [GO:0060492]; male gonad development [GO:0008584]; mesenchymal-epithelial cell signaling [GO:0060638]; neuron differentiation [GO:0030182]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190] GO:0002062; GO:0002088; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0008584; GO:0009267; GO:0021871; GO:0030182; GO:0043231; GO:0045165; GO:0060070; GO:0060492; GO:0060638; GO:0061072; GO:0061303; GO:0062023; GO:0071425; GO:0090190 25757 FUN_017814 0 10 0 18 4 ptg000012l:704367-709513 P28094 7.25e-52 Protein Wnt-1 Strongylocentrotus purpuratus (Purple sea urchin) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; neuron differentiation [GO:0030182] GO:0005109; GO:0005125; GO:0005615; GO:0030182; GO:0045165; GO:0060070 25758 FUN_017819 169 120 114 103 28 NA NA NA NA NA NA NA 25759 FUN_017818 21 98 31 59 34 NA NA NA NA NA NA NA 25760 FUN_035361 95 15 12 18 40 NA NA NA NA NA NA NA 25761 FUN_035360 448 621 222 389 407 ptg000025l:6762824-6771010 Q97UU4 2.04e-29 Uncharacterized protein SSO2899 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) NA NA 25762 FUN_035363 0 0 25 0 17 NA NA NA NA NA NA NA 25763 FUN_035362 5 0 27 0 77 NA NA NA NA NA NA NA 25764 FUN_035365 0 0 0 0 9 NA NA NA NA NA NA NA 25765 FUN_035364 125 198 60 258 73 ptg000025l:6822035-6823055 Q8K4Z4 9.43e-29 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Cavia porcellus (Guinea pig) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0006366; GO:0006898; GO:0006939; GO:0007189; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 25766 FUN_035367 78 77 22 44 32 ptg000025l:6835278-6836304 Q28509 2.56e-34 Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor) Macaca mulatta (Rhesus macaque) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; bone resorption [GO:0045453]; brown fat cell differentiation [GO:0050873]; cellular response to amyloid-beta [GO:1904646]; desensitization of G protein-coupled receptor signaling pathway by arrestin [GO:0002032]; diet induced thermogenesis [GO:0002024]; heat generation [GO:0031649]; negative regulation of multicellular organism growth [GO:0040015]; negative regulation of smooth muscle contraction [GO:0045986]; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure [GO:0002025]; positive regulation of AMPA receptor activity [GO:2000969]; positive regulation of autophagosome maturation [GO:1901098]; positive regulation of bone mineralization [GO:0030501]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of lipophagy [GO:1904504]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of mini excitatory postsynaptic potential [GO:0061885]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of transcription by RNA polymerase II [GO:0045944]; receptor-mediated endocytosis [GO:0006898]; regulation of sodium ion transport [GO:0002028]; response to cold [GO:0009409]; smooth muscle contraction [GO:0006939]; transcription by RNA polymerase II [GO:0006366] GO:0001540; GO:0002024; GO:0002025; GO:0002028; GO:0002032; GO:0004930; GO:0004941; GO:0005634; GO:0005769; GO:0005794; GO:0005886; GO:0006366; GO:0006898; GO:0006939; GO:0007190; GO:0008179; GO:0009409; GO:0010739; GO:0015459; GO:0016324; GO:0030501; GO:0031649; GO:0040015; GO:0042803; GO:0043235; GO:0043410; GO:0044877; GO:0045453; GO:0045944; GO:0045986; GO:0050873; GO:0051380; GO:0061885; GO:0071880; GO:0071902; GO:0098992; GO:0120162; GO:1901098; GO:1904504; GO:1904646; GO:2000969 25767 FUN_035366 0 33 22 42 49 NA NA NA NA NA NA NA 25768 FUN_035369 331 480 719 629 319 NA NA NA NA NA NA NA 25769 FUN_035368 153 306 325 1039 542 NA NA NA NA NA NA NA 25770 FUN_031499 742 516 326 862 864 NA NA NA NA NA NA NA 25771 FUN_016433 532 449 438 559 621 NA NA NA NA NA NA NA 25772 FUN_031844 33 0 44 14 78 NA NA NA NA NA NA NA 25773 FUN_031845 34 15 21 94 18 ptg000023l:25983548-25984865 Q9W0Y8 3.13e-72 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 25774 FUN_031846 23 46 83 15 39 NA NA NA NA NA NA NA 25775 FUN_031847 7 0 33 2 120 NA NA NA NA NA NA NA 25776 FUN_031840 1821 1073 951 1767 2214 ptg000023l:25926425-25931752 Q13435 6.14e-28 Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145) Homo sapiens (Human) mRNA processing [GO:0006397]; mRNA splicing, via spliceosome [GO:0000398]; RNA splicing [GO:0008380]; U2-type prespliceosome assembly [GO:1903241] GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0005681; GO:0005684; GO:0005686; GO:0005689; GO:0006397; GO:0008380; GO:0016607; GO:0071005; GO:0071011; GO:0071013; GO:1903241 25777 FUN_031841 41844 42964 27546 50588 44589 ptg000023l:25935286-25958326 Q9VT65 3.56e-29 Calpain-B (EC 3.4.22.-) (Calcium-activated neutral proteinase B) (CANP B) [Cleaved into: Calpain-B catalytic subunit 1; Calpain-B catalytic subunit 2] Drosophila melanogaster (Fruit fly) border follicle cell migration [GO:0007298]; neuron remodeling [GO:0016322]; protein autoprocessing [GO:0016540]; proteolysis [GO:0006508] GO:0004198; GO:0005509; GO:0005737; GO:0006508; GO:0007298; GO:0016020; GO:0016322; GO:0016540 25778 FUN_031842 38 0 0 0 17 NA NA NA NA NA NA NA 25779 FUN_031843 52 16 11 73 22 ptg000023l:25967903-25978873 Q9W0Y8 1.79e-37 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 25780 FUN_031848 554 585 302 463 652 NA NA NA NA NA NA NA 25781 FUN_031849 374 389 120 169 387 ptg000023l:26017175-26026079 A5D6U8 2.68e-22 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003993; GO:0005576; GO:0046872 25782 FUN_031849 374 389 120 169 387 ptg000023l:26017175-26026079 A5D6U8 2.68e-22 Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0003993; GO:0005576; GO:0046872 25783 FUN_038678 14 0 0 0 0 NA NA NA NA NA NA NA 25784 FUN_038679 294 0 229 0 0 NA NA NA NA NA NA NA 25785 FUN_030466 8 0 11 0 35 ptg000023l:10935109-10935872 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 25786 FUN_030460 3 0 4 0 7 ptg000023l:10919922-10922234 P35061 6.53e-78 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 25787 FUN_030462 9 0 10 1 33 ptg000023l:10927002-10927765 P84239 5.16e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 25788 FUN_038671 1087 482 285 430 600 NA NA NA NA NA NA NA 25789 FUN_038672 127 19 16 0 4 ptg000027l:10003290-10008150 Q2TB18 2.85e-31 Protein asteroid homolog 1 Homo sapiens (Human) NA GO:0004518 25790 FUN_038674 16 7 14 15 18 NA NA NA NA NA NA NA 25791 FUN_038675 0 27 0 0 98 NA NA NA NA NA NA NA 25792 FUN_038676 29 31 21 24 21 ptg000027l:10038960-10040265 Q80XJ3 2.11e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25793 FUN_038677 0 8 0 9 27 NA NA NA NA NA NA NA 25794 FUN_031598 87 88 74 94 99 NA NA NA NA NA NA NA 25795 FUN_031599 4 6 0 5 4 NA NA NA NA NA NA NA 25796 FUN_031596 1869 1378 844 1337 1317 ptg000023l:23256817-23271749 Q80YS5 9.1e-24 Leucine-rich repeat-containing protein 27 Mus musculus (Mouse) NA NA 25797 FUN_031597 1402 2282 1330 1350 1889 NA NA NA NA NA NA NA 25798 FUN_031594 29 21 26 21 114 NA NA NA NA NA NA NA 25799 FUN_031595 1575 860 596 1016 951 NA NA NA NA NA NA NA 25800 FUN_031592 3507 2249 966 1938 1977 NA NA NA NA NA NA NA 25801 FUN_031593 1410 1356 896 614 1005 NA NA NA NA NA NA NA 25802 FUN_031590 1489 1243 546 1483 1056 NA NA NA NA NA NA NA 25803 FUN_031591 4345 3621 1109 3156 2058 NA NA NA NA NA NA NA 25804 FUN_038044 110 176 490 651 207 NA NA NA NA NA NA NA 25805 FUN_040362 0 0 0 0 161 NA NA NA NA NA NA NA 25806 FUN_001902 509 780 575 778 860 NA NA NA NA NA NA NA 25807 FUN_001903 1968 3313 1242 1188 867 NA NA NA NA NA NA NA 25808 FUN_001900 149 81 55 95 137 ntLink_6:17576309-17577735 Q9D1I6 5.13e-25 39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14) Mus musculus (Mouse) mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005762; GO:0032543 25809 FUN_001901 795 284 268 272 482 NA NA NA NA NA NA NA 25810 FUN_001906 1573 813 692 1204 1046 NA NA NA NA NA NA NA 25811 FUN_001907 31 0 32 19 30 NA NA NA NA NA NA NA 25812 FUN_001904 1819 3087 1690 1946 1108 NA NA NA NA NA NA NA 25813 FUN_001905 6022 6334 3792 6614 3771 NA NA NA NA NA NA NA 25814 FUN_001908 6345 10522 4378 6655 3563 NA NA NA NA NA NA NA 25815 FUN_001909 657 437 417 798 815 ntLink_6:17657269-17660950 Q9VKM6 6.17e-34 Vacuolar protein sorting-associated protein 72 homolog (Protein YL-1) Drosophila melanogaster (Fruit fly) DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of gene expression [GO:0010629]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0006355; GO:0010629; GO:0035267; GO:0140849; GO:0140861 25816 FUN_007940 53 2 59 1 96 NA NA NA NA NA NA NA 25817 FUN_007941 98 55 96 0 422 NA NA NA NA NA NA NA 25818 FUN_007943 352 316 283 349 1076 NA NA NA NA NA NA NA 25819 FUN_018220 23 0 21 42 16 NA NA NA NA NA NA NA 25820 FUN_036108 137 215 105 174 124 ptg000025l:15462941-15470242 P25867 3.2e-37 Ubiquitin-conjugating enzyme E2-17 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme D1) (Protein effete) (Ubiquitin carrier protein) (Ubiquitin-protein ligase) Drosophila melanogaster (Fruit fly) anaphase-promoting complex-dependent catabolic process [GO:0031145]; chromosome organization [GO:0051276]; compound eye morphogenesis [GO:0001745]; compound eye photoreceptor cell differentiation [GO:0001751]; female germ-line stem cell asymmetric division [GO:0048132]; germ-line stem cell population maintenance [GO:0030718]; male meiotic nuclear division [GO:0007140]; mitotic cell cycle [GO:0000278]; negative regulation of smoothened signaling pathway [GO:0045879]; neuron remodeling [GO:0016322]; peptidoglycan recognition protein signaling pathway [GO:0061057]; protein linear polyubiquitination [GO:0097039]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of protein stability [GO:0031647]; regulation of R7 cell differentiation [GO:0045676]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000278; GO:0001745; GO:0001751; GO:0005524; GO:0005634; GO:0005829; GO:0006511; GO:0007140; GO:0016322; GO:0016567; GO:0030718; GO:0031145; GO:0031625; GO:0031647; GO:0045676; GO:0045879; GO:0048132; GO:0051276; GO:0061057; GO:0061631; GO:0097039 25821 FUN_036109 183 302 131 362 560 NA NA NA NA NA NA NA 25822 FUN_031338 54 0 14 8 0 NA NA NA NA NA NA NA 25823 FUN_031339 140 89 141 33 222 ptg000023l:19795141-19815288 Q7RTR2 2.11e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25824 FUN_031339 140 89 141 33 222 ptg000023l:19795141-19815288 Q7RTR2 6.07e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25825 FUN_031339 140 89 141 33 222 ptg000023l:19795141-19815288 Q7RTR2 2.42e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25826 FUN_031339 140 89 141 33 222 ptg000023l:19795141-19815288 Q7RTR2 1.65e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 25827 FUN_008059 266 282 136 303 220 NA NA NA NA NA NA NA 25828 FUN_031332 5 10 5 9 8 NA NA NA NA NA NA NA 25829 FUN_036101 43964 28715 26406 44733 35140 NA NA NA NA NA NA NA 25830 FUN_036102 3056 1602 1668 3563 2084 ptg000025l:15410257-15411349 Q0P8I7 1.47e-82 GDP-D-glycero-alpha-D-manno-heptose dehydrogenase (EC 1.1.98.-) Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) capsule polysaccharide biosynthetic process [GO:0045227]; protein homotetramerization [GO:0051289] GO:0003978; GO:0016491; GO:0019003; GO:0042802; GO:0045227; GO:0051289; GO:0070404 25831 FUN_024409 76 11 6 31 0 NA NA NA NA NA NA NA 25832 FUN_031336 234 544 210 45 170 NA NA NA NA NA NA NA 25833 FUN_036105 317 289 75 148 265 NA NA NA NA NA NA NA 25834 FUN_036106 887 628 326 689 491 NA NA NA NA NA NA NA 25835 FUN_031335 3 69 0 0 0 NA NA NA NA NA NA NA 25836 FUN_008056 1602 1378 539 1587 1566 NA NA NA NA NA NA NA 25837 FUN_039101 3523 1854 2012 1880 1724 ptg000027l:14651177-14656945 P27600 1.58e-92 Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) Mus musculus (Mouse) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; multicellular organism aging [GO:0010259]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of blood pressure [GO:0008217]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to xenobiotic stimulus [GO:0009410]; Rho protein signal transduction [GO:0007266] GO:0001664; GO:0001701; GO:0003924; GO:0005525; GO:0005737; GO:0005834; GO:0007186; GO:0007188; GO:0007266; GO:0008217; GO:0008360; GO:0009410; GO:0010259; GO:0010762; GO:0016328; GO:0019888; GO:0030154; GO:0031526; GO:0031683; GO:0031752; GO:0032006; GO:0032434; GO:0032516; GO:0035556; GO:0042733; GO:0043005; GO:0043025; GO:0046872; GO:0051721; GO:1904706; GO:1904753 25838 FUN_039101 3523 1854 2012 1880 1724 ptg000027l:14651177-14656945 P27600 6.8e-34 Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) Mus musculus (Mouse) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell differentiation [GO:0030154]; embryonic digit morphogenesis [GO:0042733]; G protein-coupled receptor signaling pathway [GO:0007186]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; multicellular organism aging [GO:0010259]; negative regulation of vascular associated smooth muscle cell migration [GO:1904753]; negative regulation of vascular associated smooth muscle cell proliferation [GO:1904706]; positive regulation of phosphoprotein phosphatase activity [GO:0032516]; regulation of blood pressure [GO:0008217]; regulation of cell shape [GO:0008360]; regulation of fibroblast migration [GO:0010762]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; regulation of TOR signaling [GO:0032006]; response to xenobiotic stimulus [GO:0009410]; Rho protein signal transduction [GO:0007266] GO:0001664; GO:0001701; GO:0003924; GO:0005525; GO:0005737; GO:0005834; GO:0007186; GO:0007188; GO:0007266; GO:0008217; GO:0008360; GO:0009410; GO:0010259; GO:0010762; GO:0016328; GO:0019888; GO:0030154; GO:0031526; GO:0031683; GO:0031752; GO:0032006; GO:0032434; GO:0032516; GO:0035556; GO:0042733; GO:0043005; GO:0043025; GO:0046872; GO:0051721; GO:1904706; GO:1904753 25839 FUN_039100 39 9 7 7 0 NA NA NA NA NA NA NA 25840 FUN_039103 0 0 0 0 6 NA NA NA NA NA NA NA 25841 FUN_039107 0 0 7 0 4 NA NA NA NA NA NA NA 25842 FUN_024405 212 18 150 189 58 ptg000018l:5886274-5887393 P21452 6.9e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Homo sapiens (Human) intestine smooth muscle contraction [GO:0014827]; muscle contraction [GO:0006936]; negative regulation of luteinizing hormone secretion [GO:0033685]; operant conditioning [GO:0035106]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of flagellated sperm motility [GO:1902093]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of uterine smooth muscle contraction [GO:0070474]; positive regulation of vascular permeability [GO:0043117]; prolactin secretion [GO:0070459]; response to electrical stimulus [GO:0051602]; tachykinin receptor signaling pathway [GO:0007217] GO:0004995; GO:0005886; GO:0006936; GO:0007217; GO:0014057; GO:0014827; GO:0016497; GO:0033685; GO:0035106; GO:0036126; GO:0043117; GO:0045987; GO:0051602; GO:0061827; GO:0070459; GO:0070474; GO:0097225; GO:1902093 25843 FUN_037859 1366 943 647 1170 1264 NA NA NA NA NA NA NA 25844 FUN_037858 89 0 56 148 125 NA NA NA NA NA NA NA 25845 FUN_037855 20 2 19 0 57 NA NA NA NA NA NA NA 25846 FUN_037854 0 0 30 0 97 NA NA NA NA NA NA NA 25847 FUN_037857 139 0 27 27 40 NA NA NA NA NA NA NA 25848 FUN_037856 0 0 0 15 0 NA NA NA NA NA NA NA 25849 FUN_037851 4584 3557 2743 3044 1511 NA NA NA NA NA NA NA 25850 FUN_037850 1315 1035 919 1414 1133 NA NA NA NA NA NA NA 25851 FUN_037853 562 546 346 351 435 ptg000026l:14390323-14395458 P38487 7.21e-73 Creatinase (EC 3.5.3.3) (Creatine amidinohydrolase) Bacillus sp. (strain B-0618) NA GO:0016980 25852 FUN_037853 562 546 346 351 435 ptg000026l:14390323-14395458 P38487 4.25e-29 Creatinase (EC 3.5.3.3) (Creatine amidinohydrolase) Bacillus sp. (strain B-0618) NA GO:0016980 25853 FUN_037852 420 315 176 263 219 NA NA NA NA NA NA NA 25854 FUN_008051 493 375 571 657 294 NA NA NA NA NA NA NA 25855 FUN_008050 184 213 136 138 388 NA NA NA NA NA NA NA 25856 FUN_032446 276 152 175 48 64 NA NA NA NA NA NA NA 25857 FUN_027278 0 0 0 25 0 NA NA NA NA NA NA NA 25858 FUN_027279 0 30 8 90 23 NA NA NA NA NA NA NA 25859 FUN_012416 284 268 234 285 225 ptg000008l:8765386-8772256 Q8BH60 1.91e-26 Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (PDZ protein interacting specifically with TC10) (PIST) Mus musculus (Mouse) autophagy [GO:0006914]; negative regulation of anion channel activity [GO:0010360]; negative regulation of protein localization to cell surface [GO:2000009]; protein transport [GO:0015031]; spermatid nucleus differentiation [GO:0007289] GO:0000139; GO:0005109; GO:0005737; GO:0005794; GO:0005886; GO:0006914; GO:0007289; GO:0008022; GO:0010360; GO:0014069; GO:0015031; GO:0016020; GO:0019905; GO:0030140; GO:0030425; GO:0030695; GO:0032991; GO:0042802; GO:0042803; GO:0044325; GO:0045202; GO:0140313; GO:2000009 25860 FUN_027270 715 6 325 17 40 NA NA NA NA NA NA NA 25861 FUN_027271 0 10 32 59 25 NA NA NA NA NA NA NA 25862 FUN_027272 8 22 6 3 16 NA NA NA NA NA NA NA 25863 FUN_027273 0 0 0 0 15 NA NA NA NA NA NA NA 25864 FUN_027274 0 0 0 0 14 NA NA NA NA NA NA NA 25865 FUN_027275 291 461 245 380 219 NA NA NA NA NA NA NA 25866 FUN_027276 429 191 561 1354 734 NA NA NA NA NA NA NA 25867 FUN_037279 134 170 157 123 262 NA NA NA NA NA NA NA 25868 FUN_028671 3 1 4 1 11 NA NA NA NA NA NA NA 25869 FUN_028670 3 2 3 1 6 NA NA NA NA NA NA NA 25870 FUN_037273 7 0 19 0 22 NA NA NA NA NA NA NA 25871 FUN_037272 11 24 21 85 46 NA NA NA NA NA NA NA 25872 FUN_037275 336 541 297 242 118 NA NA NA NA NA NA NA 25873 FUN_037274 71 45 56 32 36 ptg000026l:7962183-7979923 P14381 5.56e-26 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 25874 FUN_037274 71 45 56 32 36 ptg000026l:7962183-7979923 P14381 5.56e-26 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 25875 FUN_037277 0 0 29 0 0 NA NA NA NA NA NA NA 25876 FUN_037276 0 25 95 0 7 NA NA NA NA NA NA NA 25877 FUN_026211 1293 642 1023 3636 3212 NA NA NA NA NA NA NA 25878 FUN_026210 461 286 668 1400 1594 NA NA NA NA NA NA NA 25879 FUN_005379 240 4 0 160 9 NA NA NA NA NA NA NA 25880 FUN_005378 0 0 0 0 36 NA NA NA NA NA NA NA 25881 FUN_015059 824 725 426 619 697 ptg000009l:5705907-5707185 Q5EB73 8.19e-39 Post-GPI attachment to proteins factor 4 (Post-GPI attachment to proteins GalNAc transferase 4) (Transmembrane protein 246) Rattus norvegicus (Rat) GPI anchor biosynthetic process [GO:0006506] GO:0000139; GO:0006506; GO:0016757 25882 FUN_005377 25 0 1 57 0 NA NA NA NA NA NA NA 25883 FUN_005376 8 0 5 0 16 NA NA NA NA NA NA NA 25884 FUN_005371 8592 16977 7413 12927 10839 NA NA NA NA NA NA NA 25885 FUN_005370 184 261 103 74 102 NA NA NA NA NA NA NA 25886 FUN_005373 1213 596 473 879 903 NA NA NA NA NA NA NA 25887 FUN_005372 32306 34858 17129 44959 41779 ntLink_8:34525044-34540261 Q71U34 0 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 25888 FUN_005372 32306 34858 17129 44959 41779 ntLink_8:34525044-34540261 Q71U34 0 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 25889 FUN_005372 32306 34858 17129 44959 41779 ntLink_8:34525044-34540261 Q71U34 6.85e-43 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 25890 FUN_005372 32306 34858 17129 44959 41779 ntLink_8:34525044-34540261 Q71U34 6.85e-43 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 25891 FUN_005372 32306 34858 17129 44959 41779 ntLink_8:34525044-34540261 Q71U34 6.66e-37 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 25892 FUN_004422 1158 990 951 1818 1320 ntLink_8:23122811-23126021 Q9H553 9.35e-52 Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; response to calcium ion [GO:0051592] GO:0000033; GO:0004378; GO:0005634; GO:0005737; GO:0005789; GO:0006486; GO:0006488; GO:0006490; GO:0016020; GO:0046982; GO:0047485; GO:0048306; GO:0048471; GO:0051592; GO:0102704 25893 FUN_004422 1158 990 951 1818 1320 ntLink_8:23122811-23126021 Q9H553 2.02e-43 Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase) Homo sapiens (Human) dolichol-linked oligosaccharide biosynthetic process [GO:0006488]; oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein glycosylation [GO:0006486]; response to calcium ion [GO:0051592] GO:0000033; GO:0004378; GO:0005634; GO:0005737; GO:0005789; GO:0006486; GO:0006488; GO:0006490; GO:0016020; GO:0046982; GO:0047485; GO:0048306; GO:0048471; GO:0051592; GO:0102704 25894 FUN_004423 2136 1337 833 1344 1864 ntLink_8:23126215-23133100 Q9NPF5 3.52e-23 DNA methyltransferase 1-associated protein 1 (DNMAP1) (DNMT1-associated protein 1) Homo sapiens (Human) chromatin remodeling [GO:0006338]; DNA methylation [GO:0006306]; DNA repair [GO:0006281]; histone acetylation [GO:0016573]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of protein import into nucleus [GO:0042307]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair [GO:2000779]; response to ethanol [GO:0045471] GO:0000122; GO:0000786; GO:0000812; GO:0003714; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0005829; GO:0006281; GO:0006306; GO:0006338; GO:0006355; GO:0016573; GO:0035267; GO:0042307; GO:0042981; GO:0043967; GO:0043968; GO:0045471; GO:0045892; GO:0045893; GO:0051726; GO:0061629; GO:1905168; GO:2000779 25895 FUN_003432 284 220 407 392 362 NA NA NA NA NA NA NA 25896 FUN_004421 6991 5738 3428 5886 5480 NA NA NA NA NA NA NA 25897 FUN_004426 3 0 0 14 0 NA NA NA NA NA NA NA 25898 FUN_004427 68 4 25 68 14 ntLink_8:23152752-23154057 Q09081 9.57e-71 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 25899 FUN_004424 164 38 104 161 198 ntLink_8:23135189-23140310 P28476 4.91e-21 Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; gamma-aminobutyric acid signaling pathway [GO:0007214]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; visual perception [GO:0007601] GO:0004890; GO:0005231; GO:0005254; GO:0005886; GO:0007165; GO:0007214; GO:0007268; GO:0007601; GO:0019904; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0098982; GO:1902476; GO:1902711; GO:1904315 25900 FUN_004425 9 30 24 21 13 NA NA NA NA NA NA NA 25901 FUN_003438 44 0 0 0 0 NA NA NA NA NA NA NA 25902 FUN_004428 884 2116 1163 458 409 NA NA NA NA NA NA NA 25903 FUN_004429 114 87 102 44 52 NA NA NA NA NA NA NA 25904 FUN_004406 395 356 532 872 548 ntLink_8:22942048-22944804 Q9BUJ2 2.07e-99 Heterogeneous nuclear ribonucleoprotein U-like protein 1 (Adenovirus early region 1B-associated protein 5) (E1B-55 kDa-associated protein 5) (E1B-AP5) Homo sapiens (Human) response to virus [GO:0009615]; RNA processing [GO:0006396] GO:0003723; GO:0005634; GO:0005654; GO:0006396; GO:0009615; GO:0019899; GO:0045202; GO:1990904 25905 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 4.83e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25906 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 4.95e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25907 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 1.18e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25908 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 1.47e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25909 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 6.28e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25910 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 2.39e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25911 FUN_028954 420 385 255 642 466 ptg000022l:6352206-6356534 Q80XJ3 6.02e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25912 FUN_015054 2274 1452 1356 2035 1500 NA NA NA NA NA NA NA 25913 FUN_028956 1744 2023 1084 1304 1048 ptg000022l:6388333-6392950 Q86YS6 2.16e-33 Ras-related protein Rab-43 (Ras-related protein Rab-41) Homo sapiens (Human) autophagosome assembly [GO:0000045]; cellular response to type II interferon [GO:0071346]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; phagosome maturation [GO:0090382]; retrograde transport, plasma membrane to Golgi [GO:0035526]; toxin transport [GO:1901998]; virion assembly [GO:0019068] GO:0000045; GO:0003924; GO:0005525; GO:0005794; GO:0006886; GO:0007030; GO:0012505; GO:0019068; GO:0030670; GO:0032588; GO:0035526; GO:0045335; GO:0070062; GO:0071346; GO:0090382; GO:1901998 25914 FUN_006482 313 557 81 376 310 NA NA NA NA NA NA NA 25915 FUN_006483 861 121 124 346 140 NA NA NA NA NA NA NA 25916 FUN_032739 36 0 0 2 0 NA NA NA NA NA NA NA 25917 FUN_032738 2304 1912 1013 1206 1907 NA NA NA NA NA NA NA 25918 FUN_006486 0 208 143 241 242 NA NA NA NA NA NA NA 25919 FUN_006484 33 70 54 91 247 NA NA NA NA NA NA NA 25920 FUN_006485 0 0 0 23 0 NA NA NA NA NA NA NA 25921 FUN_032733 39 71 43 31 55 ptg000023l:35366036-35379524 Q9NBX4 9.58e-38 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 25922 FUN_032732 51 0 0 0 0 NA NA NA NA NA NA NA 25923 FUN_032731 28 61 24 104 225 NA NA NA NA NA NA NA 25924 FUN_032737 416 1560 823 764 336 ptg000023l:35397698-35398187 A7SPE8 8.42e-37 Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog) Nematostella vectensis (Starlet sea anemone) NA GO:0030133; GO:0031083 25925 FUN_032736 362 132 223 19 883 NA NA NA NA NA NA NA 25926 FUN_032735 0 0 0 0 38 NA NA NA NA NA NA NA 25927 FUN_032734 96 0 8 4 89 NA NA NA NA NA NA NA 25928 FUN_028952 747 287 210 536 468 ptg000022l:6311346-6316262 Q9NSA2 5.02e-55 Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) Homo sapiens (Human) potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0008076; GO:0014069; GO:0016020; GO:0034765; GO:0043025; GO:0043197; GO:0045211; GO:0046872; GO:0051260; GO:0071805 25929 FUN_031501 348 493 253 418 298 ptg000023l:22070020-22078745 Q6DB24 2.43e-29 Glyoxylate/hydroxypyruvate reductase B (EC 1.1.1.79) (EC 1.1.1.81) Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) NA GO:0005737; GO:0005886; GO:0008465; GO:0016618; GO:0030267; GO:0051287 25930 FUN_015052 644 598 362 529 446 NA NA NA NA NA NA NA 25931 FUN_031500 769 1153 437 732 344 NA NA NA NA NA NA NA 25932 FUN_034779 3954 2341 2071 2042 5188 NA NA NA NA NA NA NA 25933 FUN_034778 43 32 11 43 51 NA NA NA NA NA NA NA 25934 FUN_034775 272 0 44 0 0 NA NA NA NA NA NA NA 25935 FUN_034774 49 0 200 3 16 NA NA NA NA NA NA NA 25936 FUN_034777 104 20 23 38 159 NA NA NA NA NA NA NA 25937 FUN_034776 5 12 607 0 7 NA NA NA NA NA NA NA 25938 FUN_034771 0 12 1 11 15 NA NA NA NA NA NA NA 25939 FUN_034770 5 3 11 2 117 NA NA NA NA NA NA NA 25940 FUN_034773 0 0 13 0 0 NA NA NA NA NA NA NA 25941 FUN_034772 70 227 102 192 518 NA NA NA NA NA NA NA 25942 FUN_001289 3022 1625 1374 3500 2474 ntLink_6:10822023-10840744 Q9ULJ6 5.44e-26 Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17) Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; artery morphogenesis [GO:0048844]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of nucleic acid-templated transcription [GO:1903508]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pyramidal neuron migration to cerebral cortex [GO:0021852]; regulation of protein sumoylation [GO:0033233]; regulation of transcription by RNA polymerase II [GO:0006357]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296] GO:0001570; GO:0001701; GO:0003007; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0007179; GO:0007296; GO:0008270; GO:0021852; GO:0030374; GO:0030521; GO:0033233; GO:0045582; GO:0045747; GO:0045944; GO:0046332; GO:0048146; GO:0048589; GO:0048844; GO:0060395; GO:0090398; GO:1903508 25943 FUN_001289 3022 1625 1374 3500 2474 ntLink_6:10822023-10840744 Q9ULJ6 5.44e-26 Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17) Homo sapiens (Human) androgen receptor signaling pathway [GO:0030521]; artery morphogenesis [GO:0048844]; cellular senescence [GO:0090398]; developmental growth [GO:0048589]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of nucleic acid-templated transcription [GO:1903508]; positive regulation of T cell differentiation [GO:0045582]; positive regulation of transcription by RNA polymerase II [GO:0045944]; pyramidal neuron migration to cerebral cortex [GO:0021852]; regulation of protein sumoylation [GO:0033233]; regulation of transcription by RNA polymerase II [GO:0006357]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; vasculogenesis [GO:0001570]; vitellogenesis [GO:0007296] GO:0001570; GO:0001701; GO:0003007; GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006357; GO:0007179; GO:0007296; GO:0008270; GO:0021852; GO:0030374; GO:0030521; GO:0033233; GO:0045582; GO:0045747; GO:0045944; GO:0046332; GO:0048146; GO:0048589; GO:0048844; GO:0060395; GO:0090398; GO:1903508 25944 FUN_001288 26 177 63 244 147 ntLink_6:10792021-10796541 Q9SZJ2 1.44e-43 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 25945 FUN_001281 81 0 0 0 0 NA NA NA NA NA NA NA 25946 FUN_001280 54 0 3 0 0 NA NA NA NA NA NA NA 25947 FUN_001283 6 0 0 0 0 NA NA NA NA NA NA NA 25948 FUN_001282 1408 95 151 148 160 NA NA NA NA NA NA NA 25949 FUN_001284 515 0 41 6 116 NA NA NA NA NA NA NA 25950 FUN_001287 924 319 320 258 139 NA NA NA NA NA NA NA 25951 FUN_001286 576 364 97 383 327 ntLink_6:10746669-10750913 Q9SZJ2 3.6e-43 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 25952 FUN_002741 0 0 0 0 6 NA NA NA NA NA NA NA 25953 FUN_007992 2055 892 1293 938 531 NA NA NA NA NA NA NA 25954 FUN_002743 4155 11 12 2402 4 NA NA NA NA NA NA NA 25955 FUN_007990 1016 825 667 1378 1053 NA NA NA NA NA NA NA 25956 FUN_002745 25 0 0 37 0 NA NA NA NA NA NA NA 25957 FUN_002744 1187 5 0 739 2 NA NA NA NA NA NA NA 25958 FUN_002746 700 0 0 448 0 NA NA NA NA NA NA NA 25959 FUN_007999 4142 1506 1430 2358 2088 ptg000002l:7015345-7043483 B4PRJ9 9.74e-30 Probable ATP-dependent RNA helicase spindle-E (EC 3.6.4.13) (Homeless) Drosophila yakuba (Fruit fly) dorsal appendage formation [GO:0046843]; germarium-derived oocyte fate determination [GO:0007294]; global gene silencing by mRNA cleavage [GO:0098795]; heterochromatin formation [GO:0031507]; intracellular mRNA localization [GO:0008298]; mitotic chromosome condensation [GO:0007076]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposition, DNA-mediated [GO:0000335]; oocyte karyosome formation [GO:0030717]; oocyte localization involved in germarium-derived egg chamber formation [GO:0030720]; oocyte maturation [GO:0001556]; polarity specification of anterior/posterior axis [GO:0009949]; polarity specification of dorsal/ventral axis [GO:0009951]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; regulation of pole plasm oskar mRNA localization [GO:0007317]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0000335; GO:0001556; GO:0003676; GO:0003724; GO:0005524; GO:0005634; GO:0007076; GO:0007283; GO:0007294; GO:0007317; GO:0008298; GO:0009949; GO:0009951; GO:0016887; GO:0030717; GO:0030720; GO:0031047; GO:0031507; GO:0043186; GO:0045892; GO:0046843; GO:0060213; GO:0098795 25960 FUN_007998 110 16 28 107 50 NA NA NA NA NA NA NA 25961 FUN_001133 0 0 12 0 0 NA NA NA NA NA NA NA 25962 FUN_001132 257 159 264 191 353 NA NA NA NA NA NA NA 25963 FUN_001131 68 142 109 41 64 NA NA NA NA NA NA NA 25964 FUN_001130 103 34 123 155 236 NA NA NA NA NA NA NA 25965 FUN_001137 9816 6626 5325 12365 7635 NA NA NA NA NA NA NA 25966 FUN_001136 57 125 63 180 26 ntLink_6:9008300-9009284 P61752 1.45e-24 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 25967 FUN_001135 57 52 0 43 11 NA NA NA NA NA NA NA 25968 FUN_001134 21 10 1 0 22 NA NA NA NA NA NA NA 25969 FUN_001139 20168 14363 8586 14579 6487 NA NA NA NA NA NA NA 25970 FUN_034199 36 0 29 0 27 NA NA NA NA NA NA NA 25971 FUN_034191 916 1149 505 1470 1066 NA NA NA NA NA NA NA 25972 FUN_034190 217 148 75 185 198 NA NA NA NA NA NA NA 25973 FUN_034193 199 113 40 109 200 NA NA NA NA NA NA NA 25974 FUN_034192 216 95 79 172 82 NA NA NA NA NA NA NA 25975 FUN_034195 30 32 17 38 29 NA NA NA NA NA NA NA 25976 FUN_034194 48 60 6 0 38 NA NA NA NA NA NA NA 25977 FUN_034197 6 0 11 14 36 NA NA NA NA NA NA NA 25978 FUN_034196 0 203 35 0 320 NA NA NA NA NA NA NA 25979 FUN_011767 13 4 14 28 60 NA NA NA NA NA NA NA 25980 FUN_011766 364 223 109 268 338 NA NA NA NA NA NA NA 25981 FUN_011765 1777 525 303 434 1334 NA NA NA NA NA NA NA 25982 FUN_011764 2154 1481 1328 1469 1107 ptg000008l:1108105-1140917 Q96AY4 4.59e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25983 FUN_011764 2154 1481 1328 1469 1107 ptg000008l:1108105-1140917 Q96AY4 1.89e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25984 FUN_011764 2154 1481 1328 1469 1107 ptg000008l:1108105-1140917 Q96AY4 2.03e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25985 FUN_011764 2154 1481 1328 1469 1107 ptg000008l:1108105-1140917 Q96AY4 3.1e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 25986 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 6.93e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25987 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 1.17e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25988 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 8.87e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25989 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 1.13e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25990 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 5.7e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25991 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 3.16e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25992 FUN_011763 1117 83 39 30 179 ptg000008l:1101413-1105147 Q80XJ3 7.93e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 25993 FUN_011762 15 25 28 13 18 NA NA NA NA NA NA NA 25994 FUN_000428 18 72 130 25 0 ntLink_6:2897905-2900093 A0A1D5NSM8 6.43e-21 NA NA NA NA 25995 FUN_011760 4 0 0 23 22 NA NA NA NA NA NA NA 25996 FUN_000427 171 62 12 295 0 NA NA NA NA NA NA NA 25997 FUN_000424 10 166 123 237 3 ntLink_6:2811768-2858245 A0A1D5NSM8 7.39e-22 NA NA NA NA 25998 FUN_000425 0 4 0 24 0 ntLink_6:2863956-2864987 A0A1D5NSM8 2.58e-21 NA NA NA NA 25999 FUN_000423 207 63 13 375 0 ntLink_6:2794747-2796608 A0A1D5NSM8 9.61e-21 NA NA NA NA 26000 FUN_000420 94 66 0 69 0 NA NA NA NA NA NA NA 26001 FUN_011768 49 0 0 14 11 ptg000008l:1177412-1184640 Q08832 1.68e-21 Gamma-aminobutyric acid receptor subunit beta-like (GABA(A) receptor) Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022851; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 26002 FUN_035822 602 359 339 346 329 NA NA NA NA NA NA NA 26003 FUN_035823 2318 949 1329 1993 1437 NA NA NA NA NA NA NA 26004 FUN_035820 1083 2882 520 893 541 NA NA NA NA NA NA NA 26005 FUN_035821 6171 5129 5009 4303 1809 NA NA NA NA NA NA NA 26006 FUN_035826 46 12 57 90 30 ptg000025l:12167204-12168056 Q9H6R0 2.42e-97 ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33) Homo sapiens (Human) positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of type I interferon production [GO:0032481]; translational initiation [GO:0006413] GO:0000182; GO:0003723; GO:0003724; GO:0003725; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006413; GO:0016887; GO:0032481; GO:0043023; GO:0043410; GO:0045943; GO:0051092; GO:0072559; GO:0140297; GO:1900227 26007 FUN_035827 772 474 328 477 1201 NA NA NA NA NA NA NA 26008 FUN_035824 1650 896 614 851 882 NA NA NA NA NA NA NA 26009 FUN_035825 433 323 384 225 392 ptg000025l:12162610-12165764 Q80VY9 3.93e-73 ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33) Mus musculus (Mouse) positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of type I interferon production [GO:0032481]; translational initiation [GO:0006413] GO:0000182; GO:0003723; GO:0003724; GO:0003725; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006413; GO:0016887; GO:0032481; GO:0043023; GO:0043410; GO:0045943; GO:0051092; GO:0072559; GO:0140297; GO:1900227 26010 FUN_035825 433 323 384 225 392 ptg000025l:12162610-12165764 Q80VY9 2.28e-22 ATP-dependent RNA helicase DHX33 (EC 3.6.4.13) (DEAH box protein 33) Mus musculus (Mouse) positive regulation of MAPK cascade [GO:0043410]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of type I interferon production [GO:0032481]; translational initiation [GO:0006413] GO:0000182; GO:0003723; GO:0003724; GO:0003725; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006413; GO:0016887; GO:0032481; GO:0043023; GO:0043410; GO:0045943; GO:0051092; GO:0072559; GO:0140297; GO:1900227 26011 FUN_035828 334 250 318 463 339 NA NA NA NA NA NA NA 26012 FUN_035829 550 844 230 651 530 NA NA NA NA NA NA NA 26013 FUN_023381 573 186 227 319 217 NA NA NA NA NA NA NA 26014 FUN_029319 724 616 400 793 653 NA NA NA NA NA NA NA 26015 FUN_029318 8979 7323 4536 6788 3651 ptg000023l:441199-450092 O43422 4.19e-74 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (Death-associated protein 4) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Homo sapiens (Human) negative regulation of cell population proliferation [GO:0008285]; signal transduction [GO:0007165] GO:0003677; GO:0005634; GO:0007165; GO:0008285; GO:0046872; GO:0046983 26016 FUN_029315 64 68 48 32 10 NA NA NA NA NA NA NA 26017 FUN_029314 0 0 0 1 7 NA NA NA NA NA NA NA 26018 FUN_029317 846 455 436 481 543 ptg000023l:419806-434177 Q5XI28 7.2e-23 Ribonucleoprotein PTB-binding 1 (Protein raver-1) Rattus norvegicus (Rat) regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000381; GO:0003729; GO:0005634; GO:0005737 26019 FUN_029316 65 6 0 22 43 NA NA NA NA NA NA NA 26020 FUN_029310 4383 2587 1949 3999 3889 NA NA NA NA NA NA NA 26021 FUN_029313 149 184 80 108 100 NA NA NA NA NA NA NA 26022 FUN_029312 7 0 3 0 0 NA NA NA NA NA NA NA 26023 FUN_040912 3 0 1 0 34 NA NA NA NA NA NA NA 26024 FUN_040913 1201 0 656 1094 2020 NA NA NA NA NA NA NA 26025 FUN_040910 232 7 147 50 161 NA NA NA NA NA NA NA 26026 FUN_040911 497 0 372 285 130 NA NA NA NA NA NA NA 26027 FUN_040916 176 100 49 256 82 NA NA NA NA NA NA NA 26028 FUN_040917 70 12 60 26 40 NA NA NA NA NA NA NA 26029 FUN_040914 0 0 36 0 50 NA NA NA NA NA NA NA 26030 FUN_040915 156 0 114 56 118 NA NA NA NA NA NA NA 26031 FUN_040918 47 0 54 32 71 NA NA NA NA NA NA NA 26032 FUN_040919 15 0 12 0 59 NA NA NA NA NA NA NA 26033 FUN_012524 713 548 345 388 352 NA NA NA NA NA NA NA 26034 FUN_012525 0 13 50 75 65 ptg000008l:9602198-9610264 E9PZZ1 3.19e-25 PR domain zinc finger protein 13 (EC 2.1.1.-) (PR domain-containing protein 13) Mus musculus (Mouse) GABAergic neuron differentiation [GO:0097154]; hypothalamus cell differentiation [GO:0021979]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0003682; GO:0005634; GO:0010468; GO:0021979; GO:0022008; GO:0042054; GO:0046872; GO:0061629; GO:0097154 26035 FUN_012526 21 0 0 0 14 NA NA NA NA NA NA NA 26036 FUN_012527 2291 770 926 1934 2516 NA NA NA NA NA NA NA 26037 FUN_012520 7047 6602 3491 5907 3642 ptg000008l:9571746-9577122 Q9DA80 3.71e-27 Radial spoke head protein 3 homolog B (A-kinase anchor protein RSPH3B) (Radial spoke head-like protein 2B) Mus musculus (Mouse) NA GO:0005737; GO:0005856; GO:0005929 26038 FUN_012521 48647 72084 43692 42012 33619 NA NA NA NA NA NA NA 26039 FUN_012522 0 0 8 0 0 NA NA NA NA NA NA NA 26040 FUN_012523 9778 8529 5354 8673 7898 NA NA NA NA NA NA NA 26041 FUN_012528 1809 1501 1029 1931 1861 NA NA NA NA NA NA NA 26042 FUN_012529 479 297 344 500 199 NA NA NA NA NA NA NA 26043 FUN_016234 419 93 140 421 387 NA NA NA NA NA NA NA 26044 FUN_016235 94 32 0 0 15 NA NA NA NA NA NA NA 26045 FUN_016236 597 38 184 1597 1570 NA NA NA NA NA NA NA 26046 FUN_016237 639 321 3 1644 1583 NA NA NA NA NA NA NA 26047 FUN_016230 6 0 2 0 16 NA NA NA NA NA NA NA 26048 FUN_016231 302 15 203 275 223 NA NA NA NA NA NA NA 26049 FUN_003199 17 9 5 6 18 NA NA NA NA NA NA NA 26050 FUN_003198 0 0 6 0 24 NA NA NA NA NA NA NA 26051 FUN_003196 6 0 0 0 34 NA NA NA NA NA NA NA 26052 FUN_003195 89 4 86 4 465 ntLink_8:8605795-8607568 Q9U7D0 3.51e-48 Histone H4 Mastigamoeba balamuthi (Phreatamoeba balamuthi) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26053 FUN_003194 21 0 19 5 117 NA NA NA NA NA NA NA 26054 FUN_016238 40 11 0 42 163 NA NA NA NA NA NA NA 26055 FUN_016239 21 35 0 25 32 NA NA NA NA NA NA NA 26056 FUN_043755 29 0 12 0 35 NA NA NA NA NA NA NA 26057 FUN_025294 719 652 248 1119 675 NA NA NA NA NA NA NA 26058 FUN_043756 70 0 36 6 110 NA NA NA NA NA NA NA 26059 FUN_025295 1334 1612 1005 2911 1336 NA NA NA NA NA NA NA 26060 FUN_043759 7 0 17 0 3 NA NA NA NA NA NA NA 26061 FUN_025297 6767 6297 2765 5854 1632 NA NA NA NA NA NA NA 26062 FUN_025290 49 10 67 141 92 NA NA NA NA NA NA NA 26063 FUN_022243 1012 644 444 852 1141 NA NA NA NA NA NA NA 26064 FUN_028042 3063 2735 1706 2612 588 NA NA NA NA NA NA NA 26065 FUN_023011 3531 2396 3602 3919 2739 NA NA NA NA NA NA NA 26066 FUN_028040 782 467 246 401 219 NA NA NA NA NA NA NA 26067 FUN_023013 3441 3374 1843 3175 2425 NA NA NA NA NA NA NA 26068 FUN_028047 298 69 17 30 10 NA NA NA NA NA NA NA 26069 FUN_028044 2 0 13 15 0 NA NA NA NA NA NA NA 26070 FUN_028045 303 19 42 9 9 NA NA NA NA NA NA NA 26071 FUN_023018 0 4 4 2 7 NA NA NA NA NA NA NA 26072 FUN_023019 508 624 279 654 403 NA NA NA NA NA NA NA 26073 FUN_028048 0 0 0 0 10 NA NA NA NA NA NA NA 26074 FUN_036845 41 201 0 81 311 ptg000026l:2628089-2629172 F8J3H2 6.05e-22 NA NA NA NA 26075 FUN_036844 4 2 1 8 0 NA NA NA NA NA NA NA 26076 FUN_036841 2697 1415 1384 3858 1769 ptg000026l:2547585-2584812 Q95SX7 4.22e-37 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26077 FUN_036840 5 23 0 16 76 NA NA NA NA NA NA NA 26078 FUN_036842 21 0 28 0 0 NA NA NA NA NA NA NA 26079 FUN_036848 98 23 38 38 14 NA NA NA NA NA NA NA 26080 FUN_020751 15 18 0 0 14 NA NA NA NA NA NA NA 26081 FUN_005990 0 0 23 61 42 NA NA NA NA NA NA NA 26082 FUN_025299 4726 7922 2717 5204 5404 NA NA NA NA NA NA NA 26083 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 8.64e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26084 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 8.64e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26085 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.99e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26086 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.99e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26087 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.07e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26088 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.07e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26089 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.89e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26090 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.89e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26091 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.03e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26092 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 2.69e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26093 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 3.18e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26094 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 3.18e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26095 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 8.3e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26096 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 2.13e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26097 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 3.2e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26098 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 4.21e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26099 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 9.17e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26100 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 2.3e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26101 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.87e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26102 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 3.21e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26103 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 5.95e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26104 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 1.5e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26105 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 3.31e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26106 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 4.59e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26107 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 9.22e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26108 FUN_028594 23 2 0 1 47 ptg000022l:1227617-1234380 Q96AY4 4.17e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26109 FUN_028596 0 0 7 22 12 NA NA NA NA NA NA NA 26110 FUN_028597 49 14 12 52 34 NA NA NA NA NA NA NA 26111 FUN_028590 6 41 6 0 7 NA NA NA NA NA NA NA 26112 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 3.81e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26113 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 3.81e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26114 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 4.82e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26115 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 4.82e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26116 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 6.76e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26117 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 6.76e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26118 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.05e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26119 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.14e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26120 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 6.03e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26121 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.11e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26122 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 2.66e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26123 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 6.51e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26124 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.16e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26125 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 3.13e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26126 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 8.97e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26127 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 2.1e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26128 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.99e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26129 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 3.46e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26130 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.53e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26131 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 4.7e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26132 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 7.76e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26133 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.64e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26134 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 5.02e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26135 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 8.18e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26136 FUN_028592 0 0 0 0 23 ptg000022l:1217111-1218820 Q96AY4 1.6e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26137 FUN_028593 0 0 0 0 6 NA NA NA NA NA NA NA 26138 FUN_010968 9197 7711 4866 6753 5861 NA NA NA NA NA NA NA 26139 FUN_010966 485 299 281 302 344 NA NA NA NA NA NA NA 26140 FUN_010967 0 1255 0 6 2 NA NA NA NA NA NA NA 26141 FUN_010964 789 455 494 577 619 ptg000007l:4911486-4915621 A0JNI4 2.71e-28 Serine racemase (EC 4.3.1.17) (EC 4.3.1.18) (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (L-serine ammonia-lyase) (L-serine dehydratase) Bos taurus (Bovine) D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to lipopolysaccharide [GO:0032496] GO:0000287; GO:0003941; GO:0005509; GO:0005524; GO:0005737; GO:0006563; GO:0008721; GO:0016594; GO:0018114; GO:0030165; GO:0030170; GO:0030378; GO:0032496; GO:0042803; GO:0042866; GO:0043025; GO:0070178; GO:0070179 26142 FUN_010965 12 25 0 2 0 NA NA NA NA NA NA NA 26143 FUN_010962 1301 869 602 1267 1318 ptg000007l:4879650-4894304 Q5DTM8 5.35e-29 E3 ubiquitin-protein ligase BRE1A (BRE1-A) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A) Mus musculus (Mouse) chromatin organization [GO:0006325]; histone H2B conserved C-terminal lysine ubiquitination [GO:0071894]; histone H2B ubiquitination [GO:0033523]; histone monoubiquitination [GO:0010390]; histone ubiquitination [GO:0016574]; negative regulation of cell migration [GO:0030336]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of histone methylation [GO:0031062]; protein polyubiquitination [GO:0000209]; regulation of DNA-templated transcription [GO:0006355]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0000209; GO:0002039; GO:0003682; GO:0003713; GO:0003730; GO:0004842; GO:0005634; GO:0005654; GO:0005730; GO:0006325; GO:0006355; GO:0006511; GO:0010390; GO:0016574; GO:0030336; GO:0031062; GO:0031625; GO:0033503; GO:0033523; GO:0042393; GO:0042802; GO:0045893; GO:0046872; GO:0061630; GO:0071894 26144 FUN_010963 998 1532 238 1622 740 ptg000007l:4908028-4910380 Q9GZT4 1.88e-34 Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17) Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to xenobiotic stimulus [GO:0009410]; serine family amino acid metabolic process [GO:0009069] GO:0000287; GO:0003941; GO:0005509; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006563; GO:0007420; GO:0007568; GO:0008721; GO:0009069; GO:0009410; GO:0016594; GO:0018114; GO:0030165; GO:0030170; GO:0030378; GO:0032496; GO:0042802; GO:0042803; GO:0042866; GO:0043025; GO:0043278; GO:0045177; GO:0070178; GO:0070179 26145 FUN_010963 998 1532 238 1622 740 ptg000007l:4908028-4910380 Q9GZT4 1.88e-34 Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17) Homo sapiens (Human) aging [GO:0007568]; brain development [GO:0007420]; D-serine biosynthetic process [GO:0070179]; D-serine metabolic process [GO:0070178]; L-serine metabolic process [GO:0006563]; pyruvate biosynthetic process [GO:0042866]; response to lipopolysaccharide [GO:0032496]; response to morphine [GO:0043278]; response to xenobiotic stimulus [GO:0009410]; serine family amino acid metabolic process [GO:0009069] GO:0000287; GO:0003941; GO:0005509; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006563; GO:0007420; GO:0007568; GO:0008721; GO:0009069; GO:0009410; GO:0016594; GO:0018114; GO:0030165; GO:0030170; GO:0030378; GO:0032496; GO:0042802; GO:0042803; GO:0042866; GO:0043025; GO:0043278; GO:0045177; GO:0070178; GO:0070179 26146 FUN_010960 1093 682 906 597 824 NA NA NA NA NA NA NA 26147 FUN_010961 2267 1968 988 2235 1278 NA NA NA NA NA NA NA 26148 FUN_042408 6 0 0 21 17 NA NA NA NA NA NA NA 26149 FUN_042409 22 1 9 5 124 NA NA NA NA NA NA NA 26150 FUN_042402 31 254 31 484 0 NA NA NA NA NA NA NA 26151 FUN_042403 0 160 4 186 0 NA NA NA NA NA NA NA 26152 FUN_042407 0 4 0 5 8 NA NA NA NA NA NA NA 26153 FUN_041669 3600 5119 2932 4712 2719 ptg000035l:6417974-6419702 Q32NT4 4.28e-56 Leucine-rich repeat-containing protein 58 Xenopus laevis (African clawed frog) NA NA 26154 FUN_011843 710 600 242 684 476 NA NA NA NA NA NA NA 26155 FUN_041667 307 151 105 836 171 NA NA NA NA NA NA NA 26156 FUN_041666 638 717 315 1033 309 NA NA NA NA NA NA NA 26157 FUN_041665 1084 486 1675 1057 1006 NA NA NA NA NA NA NA 26158 FUN_041664 0 0 28 22 64 NA NA NA NA NA NA NA 26159 FUN_041663 30 147 106 73 84 NA NA NA NA NA NA NA 26160 FUN_041662 4773 4496 2161 4113 3498 NA NA NA NA NA NA NA 26161 FUN_041661 113 100 80 86 110 NA NA NA NA NA NA NA 26162 FUN_041660 22 51 122 40 8 NA NA NA NA NA NA NA 26163 FUN_022761 23 37 28 38 44 NA NA NA NA NA NA NA 26164 FUN_022760 646 1132 22 749 325 NA NA NA NA NA NA NA 26165 FUN_022763 118 118 32 130 53 NA NA NA NA NA NA NA 26166 FUN_022762 2 29 0 63 0 NA NA NA NA NA NA NA 26167 FUN_022765 25 13 13 44 28 ptg000016l:12794647-12795058 P13903 4.36e-45 Twist-related protein (T18) (X-twist) Xenopus laevis (African clawed frog) neural crest formation [GO:0014029] GO:0003677; GO:0005634; GO:0014029; GO:0046983 26168 FUN_009121 22 0 71 0 29 NA NA NA NA NA NA NA 26169 FUN_009122 0 45 72 0 1 NA NA NA NA NA NA NA 26170 FUN_022769 17 23 17 12 32 NA NA NA NA NA NA NA 26171 FUN_022768 6585 3226 3217 5657 4513 NA NA NA NA NA NA NA 26172 FUN_011845 348 364 208 526 276 ptg000008l:2040540-2050327 P23368 5.38e-38 NAD-dependent malic enzyme, mitochondrial (NAD-ME) (EC 1.1.1.38) (Malic enzyme 2) Homo sapiens (Human) malate metabolic process [GO:0006108]; pyruvate metabolic process [GO:0006090]; regulation of NADP metabolic process [GO:1902031] GO:0004470; GO:0004471; GO:0004473; GO:0005739; GO:0005759; GO:0006090; GO:0006108; GO:0008948; GO:0009055; GO:0043231; GO:0046872; GO:0051287; GO:1902031 26173 FUN_009128 0 0 0 0 15 NA NA NA NA NA NA NA 26174 FUN_009129 9 34 50 0 129 NA NA NA NA NA NA NA 26175 FUN_029885 17 34 0 736 27 NA NA NA NA NA NA NA 26176 FUN_029884 441 457 0 115 381 ptg000023l:7341246-7382428 P34457 4.25e-24 Putative uncharacterized transposon-derived protein F54H12.3 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0015074 26177 FUN_029887 41 14 19 2 67 NA NA NA NA NA NA NA 26178 FUN_029886 37 66 33 16 10 NA NA NA NA NA NA NA 26179 FUN_029881 952 934 866 1840 1042 NA NA NA NA NA NA NA 26180 FUN_029880 820 666 273 679 318 NA NA NA NA NA NA NA 26181 FUN_029883 39 0 0 0 77 NA NA NA NA NA NA NA 26182 FUN_029882 186 346 84 180 223 NA NA NA NA NA NA NA 26183 FUN_029889 1329 763 670 0 121 NA NA NA NA NA NA NA 26184 FUN_029888 20 41 0 65 52 NA NA NA NA NA NA NA 26185 FUN_014607 900 1150 980 865 892 NA NA NA NA NA NA NA 26186 FUN_014606 454 274 248 362 319 NA NA NA NA NA NA NA 26187 FUN_013652 2341 2670 1581 1951 1588 NA NA NA NA NA NA NA 26188 FUN_040138 4269 3277 2576 3844 2729 ptg000031l:4686162-4696626 Q5NVI9 8.94e-24 DnaJ homolog subfamily A member 1 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) negative regulation of apoptotic process [GO:0043066]; negative regulation of JUN kinase activity [GO:0043508]; positive regulation of apoptotic process [GO:0043065]; protein folding [GO:0006457]; protein localization to mitochondrion [GO:0070585]; regulation of protein transport [GO:0051223]; response to heat [GO:0009408] GO:0001671; GO:0005524; GO:0005634; GO:0005739; GO:0005783; GO:0006457; GO:0009408; GO:0016020; GO:0030544; GO:0043065; GO:0043066; GO:0043508; GO:0046872; GO:0048471; GO:0051082; GO:0051087; GO:0051223; GO:0070585 26189 FUN_040139 0 0 0 20 0 NA NA NA NA NA NA NA 26190 FUN_040134 22 16 7 36 15 ptg000031l:4625949-4627134 Q9EQD2 3.87e-36 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 26191 FUN_013655 0 4 28 3 5 NA NA NA NA NA NA NA 26192 FUN_040136 5 5 12 14 33 NA NA NA NA NA NA NA 26193 FUN_040137 603 601 328 708 716 ptg000031l:4671915-4682022 Q9DC33 7.33e-31 High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein HMGX1) (Inhibitor of BRAF35) (iBRAF) Mus musculus (Mouse) chromatin organization [GO:0006325]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein sumoylation [GO:0033234]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of gene expression [GO:0010468] GO:0000122; GO:0003677; GO:0005634; GO:0006325; GO:0010468; GO:0033234; GO:0042802; GO:0045665 26194 FUN_040132 38 1309 15 58 39 NA NA NA NA NA NA NA 26195 FUN_014602 391 668 384 570 453 ptg000009l:1432293-1434905 Q9CXS4 7.1e-25 Centromere protein V (CENP-V) (Proline-rich protein 6) Mus musculus (Mouse) ameboidal-type cell migration [GO:0001667]; cell cycle [GO:0007049]; cell division [GO:0051301]; centromere complex assembly [GO:0034508]; pericentric heterochromatin formation [GO:0031508]; positive regulation of cytokinesis [GO:0032467]; regulation of chromosome organization [GO:0033044] GO:0000776; GO:0001667; GO:0005634; GO:0005654; GO:0005829; GO:0007049; GO:0015630; GO:0016846; GO:0030496; GO:0031508; GO:0031965; GO:0032467; GO:0033044; GO:0034508; GO:0046872; GO:0051233; GO:0051301 26196 FUN_014601 1166 975 685 1898 826 NA NA NA NA NA NA NA 26197 FUN_014600 42 133 121 125 103 NA NA NA NA NA NA NA 26198 FUN_015259 7106 12548 4736 7933 7308 ptg000009l:7993621-7994464 Q9MYM7 3.76e-25 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 26199 FUN_015258 415 316 290 279 449 NA NA NA NA NA NA NA 26200 FUN_015253 4 25 0 34 70 NA NA NA NA NA NA NA 26201 FUN_015252 12 15 17 8 16 NA NA NA NA NA NA NA 26202 FUN_015251 92 134 62 99 94 NA NA NA NA NA NA NA 26203 FUN_015250 0 0 0 12 0 NA NA NA NA NA NA NA 26204 FUN_015257 3701 3273 2254 3581 3093 NA NA NA NA NA NA NA 26205 FUN_015256 24680 24795 12577 19273 18216 ptg000009l:7976915-7980215 P62752 2.04e-40 60S ribosomal protein L23a Rattus norvegicus (Rat) ribosomal large subunit assembly [GO:0000027]; translation [GO:0006412] GO:0000027; GO:0003735; GO:0005634; GO:0006412; GO:0022625; GO:0022626; GO:0045202; GO:0070180; GO:1904841 26206 FUN_015255 369 576 396 570 335 NA NA NA NA NA NA NA 26207 FUN_015254 5 0 4 32 24 NA NA NA NA NA NA NA 26208 FUN_024358 323 67 175 433 250 NA NA NA NA NA NA NA 26209 FUN_024359 253 113 60 278 79 NA NA NA NA NA NA NA 26210 FUN_024356 528 186 164 475 311 NA NA NA NA NA NA NA 26211 FUN_024357 484 300 403 655 623 NA NA NA NA NA NA NA 26212 FUN_024354 809 1260 651 2260 1995 ptg000018l:5343413-5344973 Q5I0M0 3.39e-66 Histone-lysine N-methyltransferase SETMAR (EC 2.1.1.357) (SET domain and mariner transposase fusion protein homolog) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; DNA catabolic process, endonucleolytic [GO:0000737]; DNA double-strand break processing [GO:0000729]; DNA integration [GO:0015074]; double-strand break repair via nonhomologous end joining [GO:0006303]; histone H3-K36 dimethylation [GO:0097676]; histone H3-K36 methylation [GO:0010452]; histone H3-K4 methylation [GO:0051568]; histone methylation [GO:0016571]; mitotic DNA integrity checkpoint signaling [GO:0044774]; negative regulation of chromosome organization [GO:2001251]; negative regulation of DNA-templated transcription [GO:0045892]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of double-strand break repair via nonhomologous end joining [GO:2001034]; replication fork processing [GO:0031297] GO:0000014; GO:0000729; GO:0000737; GO:0003677; GO:0003690; GO:0003697; GO:0004519; GO:0005634; GO:0006303; GO:0006325; GO:0008270; GO:0008283; GO:0010452; GO:0015074; GO:0016571; GO:0031297; GO:0035861; GO:0042054; GO:0042800; GO:0042803; GO:0044547; GO:0044774; GO:0045892; GO:0046975; GO:0051568; GO:0090305; GO:0097676; GO:0140954; GO:2000373; GO:2001034; GO:2001251 26213 FUN_024355 236 471 273 539 547 NA NA NA NA NA NA NA 26214 FUN_024352 0 101 60 71 61 NA NA NA NA NA NA NA 26215 FUN_024353 3921 5883 1703 2908 1237 NA NA NA NA NA NA NA 26216 FUN_024350 3298 3201 2275 4231 2984 NA NA NA NA NA NA NA 26217 FUN_024351 66 155 215 256 203 NA NA NA NA NA NA NA 26218 FUN_038478 1030 1674 478 992 550 NA NA NA NA NA NA NA 26219 FUN_038479 588 641 331 599 656 NA NA NA NA NA NA NA 26220 FUN_038476 2005 2081 723 708 991 ptg000027l:7801803-7803727 Q2KIG2 1.63e-42 WD repeat-containing protein 5 Bos taurus (Bovine) transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0005634; GO:0035064; GO:0035097; GO:0045815; GO:0048188; GO:0071339 26221 FUN_038476 2005 2081 723 708 991 ptg000027l:7801803-7803727 Q2KIG2 2.59e-24 WD repeat-containing protein 5 Bos taurus (Bovine) transcription initiation-coupled chromatin remodeling [GO:0045815] GO:0000123; GO:0005634; GO:0035064; GO:0035097; GO:0045815; GO:0048188; GO:0071339 26222 FUN_038477 2073 1794 947 1447 790 ptg000027l:7804996-7809720 Q62083 1.16e-26 PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein) Mus musculus (Mouse) cellular response to decreased oxygen levels [GO:0036294]; cellular response to glucose starvation [GO:0042149]; dendritic spine maintenance [GO:0097062]; dendritic spine organization [GO:0097061]; glial cell development [GO:0021782]; intracellular protein transport [GO:0006886]; intracellular signal transduction [GO:0035556]; long-term synaptic depression [GO:0060292]; monoamine transport [GO:0015844]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; negative regulation of cell death [GO:0060548]; negative regulation of gene expression [GO:0010629]; positive regulation of receptor internalization [GO:0002092]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; protein phosphorylation [GO:0006468]; protein targeting [GO:0006605]; receptor clustering [GO:0043113]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of insulin secretion [GO:0050796]; regulation of kainate selective glutamate receptor activity [GO:2000312]; regulation of postsynaptic neurotransmitter receptor internalization [GO:0099149]; regulation of synapse structure or activity [GO:0050803] GO:0001664; GO:0002092; GO:0005080; GO:0005102; GO:0005484; GO:0005543; GO:0005737; GO:0005739; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006468; GO:0006605; GO:0006886; GO:0007205; GO:0008021; GO:0008022; GO:0008092; GO:0010629; GO:0014069; GO:0015844; GO:0016020; GO:0019899; GO:0019904; GO:0021782; GO:0030425; GO:0032588; GO:0032991; GO:0034315; GO:0034316; GO:0035255; GO:0035556; GO:0036294; GO:0042149; GO:0042734; GO:0042802; GO:0043005; GO:0043113; GO:0043197; GO:0045202; GO:0046872; GO:0048471; GO:0050796; GO:0050803; GO:0051015; GO:0060292; GO:0060548; GO:0071933; GO:0097061; GO:0097062; GO:0098842; GO:0098843; GO:0098978; GO:0099149; GO:0099572; GO:0140090; GO:2000312 26223 FUN_038474 34215 33113 16922 24547 27020 NA NA NA NA NA NA NA 26224 FUN_038475 8354 3068 1361 2115 2009 NA NA NA NA NA NA NA 26225 FUN_038472 1003 442 200 786 312 NA NA NA NA NA NA NA 26226 FUN_038473 2159 1681 1277 1604 989 ptg000027l:7774409-7779989 Q14894 1.49e-28 Ketimine reductase mu-crystallin (EC 1.5.1.25) (NADP-regulated thyroid-hormone-binding protein) Homo sapiens (Human) lysine catabolic process [GO:0006554]; negative regulation of transcription by RNA polymerase II [GO:0000122]; sensory perception of sound [GO:0007605]; thyroid hormone metabolic process [GO:0042403]; thyroid hormone transport [GO:0070327] GO:0000122; GO:0003714; GO:0005634; GO:0005737; GO:0005739; GO:0005782; GO:0005829; GO:0006554; GO:0007605; GO:0042403; GO:0042562; GO:0042803; GO:0047127; GO:0050661; GO:0070062; GO:0070324; GO:0070327 26227 FUN_038470 127 32 65 52 29 NA NA NA NA NA NA NA 26228 FUN_038471 43 0 0 17 0 NA NA NA NA NA NA NA 26229 FUN_028869 9 7 3 60 33 NA NA NA NA NA NA NA 26230 FUN_028864 4 0 0 0 37 NA NA NA NA NA NA NA 26231 FUN_028866 4 0 0 0 43 NA NA NA NA NA NA NA 26232 FUN_028867 0 0 6 0 61 NA NA NA NA NA NA NA 26233 FUN_028862 2 0 0 1 58 NA NA NA NA NA NA NA 26234 FUN_028863 58 107 32 50 0 NA NA NA NA NA NA NA 26235 FUN_014625 3756 2225 1513 2611 2376 NA NA NA NA NA NA NA 26236 FUN_015929 4 14 41 18 73 NA NA NA NA NA NA NA 26237 FUN_015928 1 7 1 0 0 NA NA NA NA NA NA NA 26238 FUN_042940 1324 1538 710 145 1806 NA NA NA NA NA NA NA 26239 FUN_044033 665 3860 4561 2317 4126 NA NA NA NA NA NA NA 26240 FUN_002402 14 30 71 52 58 NA NA NA NA NA NA NA 26241 FUN_030240 4 0 3 0 12 ptg000023l:10438267-10439030 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26242 FUN_044034 956 4426 8296 4262 4951 NA NA NA NA NA NA NA 26243 FUN_044037 526 5572 9447 3569 3036 NA NA NA NA NA NA NA 26244 FUN_027079 0 87 0 16 50 NA NA NA NA NA NA NA 26245 FUN_027074 27 53 21 52 18 NA NA NA NA NA NA NA 26246 FUN_027075 500 938 619 607 677 ptg000020l:16533976-16534801 Q14549 5.64e-37 Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1) Homo sapiens (Human) adult walking behavior [GO:0007628]; neuron fate commitment [GO:0048663]; proprioception [GO:0019230]; regulation of nervous system development [GO:0051960]; regulation of transcription by RNA polymerase II [GO:0006357]; sensory neuron axon guidance [GO:0097374]; spinal cord motor neuron differentiation [GO:0021522] GO:0000785; GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0007628; GO:0019230; GO:0021522; GO:0048663; GO:0051960; GO:0097374 26247 FUN_027072 108 85 48 38 88 NA NA NA NA NA NA NA 26248 FUN_027070 0 6 0 0 5 NA NA NA NA NA NA NA 26249 FUN_027071 1991 1265 683 1297 847 NA NA NA NA NA NA NA 26250 FUN_044038 183 1220 858 587 634 NA NA NA NA NA NA NA 26251 FUN_030246 3 0 2 0 19 ptg000023l:10450423-10451186 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26252 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 7.98e-93 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26253 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 1.63e-86 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26254 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 3e-77 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26255 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 2.65e-64 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26256 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 1.63e-27 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26257 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 1.6e-23 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26258 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 1.82e-22 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26259 FUN_026283 3302 1683 1594 467 2369 ptg000020l:7170843-7227855 P16157 2.32e-22 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26260 FUN_017273 0 0 0 24 0 NA NA NA NA NA NA NA 26261 FUN_017272 0 0 0 16 0 NA NA NA NA NA NA NA 26262 FUN_017271 45 104 7 36 0 NA NA NA NA NA NA NA 26263 FUN_042947 12 11 12 0 65 NA NA NA NA NA NA NA 26264 FUN_017279 6 0 0 9 5 NA NA NA NA NA NA NA 26265 FUN_001156 187 193 45 126 83 NA NA NA NA NA NA NA 26266 FUN_001151 843 824 327 738 325 ntLink_6:9172348-9178452 Q8WY64 7.6e-29 E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP) Homo sapiens (Human) cholesterol homeostasis [GO:0042632]; negative regulation of low-density lipoprotein particle clearance [GO:0010989]; negative regulation of neuron projection development [GO:0010977]; nervous system development [GO:0007399]; positive regulation of protein catabolic process [GO:0045732]; protein destabilization [GO:0031648]; protein ubiquitination [GO:0016567]; regulation of low-density lipoprotein particle receptor catabolic process [GO:0032803]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004842; GO:0005829; GO:0005856; GO:0005886; GO:0006511; GO:0007399; GO:0008092; GO:0010977; GO:0010989; GO:0016567; GO:0031648; GO:0032803; GO:0042632; GO:0045732; GO:0046872; GO:0061630 26267 FUN_001150 1329 1062 846 1229 963 ntLink_6:9169880-9171937 Q969J3 9.66e-40 BLOC-1-related complex subunit 5 (Loss of heterozygosity 12 chromosomal region 1) (Myristoylated lysosomal protein) (Myrlysin) Homo sapiens (Human) lysosome localization [GO:0032418]; organelle transport along microtubule [GO:0072384]; positive regulation of anterograde synaptic vesicle transport [GO:1903744]; regulation of endosome size [GO:0051036]; regulation of lysosome size [GO:0062196] GO:0005886; GO:0016020; GO:0030672; GO:0032418; GO:0043231; GO:0051036; GO:0062196; GO:0072384; GO:0098574; GO:0099078; GO:1903744 26268 FUN_001153 137 46 170 164 426 NA NA NA NA NA NA NA 26269 FUN_001152 1164 784 884 775 908 NA NA NA NA NA NA NA 26270 FUN_025953 0 0 8 2 3 NA NA NA NA NA NA NA 26271 FUN_038997 0 0 39 0 62 NA NA NA NA NA NA NA 26272 FUN_038996 10 106 19 0 42 NA NA NA NA NA NA NA 26273 FUN_038991 4 28 11 26 30 NA NA NA NA NA NA NA 26274 FUN_009521 33 0 0 33 78 NA NA NA NA NA NA NA 26275 FUN_038999 0 0 0 0 9 NA NA NA NA NA NA NA 26276 FUN_038998 8 0 0 0 0 NA NA NA NA NA NA NA 26277 FUN_009523 38 43 9 54 210 NA NA NA NA NA NA NA 26278 FUN_025957 0 25 3 0 0 ptg000020l:2422422-2425839 Q8BHB0 3.92e-24 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 26279 FUN_025956 392 190 184 307 76 ptg000020l:2410686-2414485 Q5DU56 7.43e-34 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26280 FUN_018140 120 30 83 208 61 NA NA NA NA NA NA NA 26281 FUN_018141 8 0 0 19 0 NA NA NA NA NA NA NA 26282 FUN_027928 183 463 202 270 192 NA NA NA NA NA NA NA 26283 FUN_027929 605 157 328 406 288 ptg000021l:13407850-13410724 Q9UBM8 4.99e-23 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0019082; GO:0046872 26284 FUN_018146 17 13 17 172 20 ptg000012l:4861432-4871827 Q9UEW3 8.54e-25 Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898] GO:0001540; GO:0001664; GO:0001934; GO:0004888; GO:0005044; GO:0005581; GO:0005737; GO:0005886; GO:0006897; GO:0006898; GO:0006911; GO:0007166; GO:0007193; GO:0030666; GO:0038024; GO:0038187; GO:0043277; GO:0045087; GO:0070374; GO:0097242 26285 FUN_018147 92 23 65 218 55 NA NA NA NA NA NA NA 26286 FUN_027924 130 65 54 35 102 NA NA NA NA NA NA NA 26287 FUN_018149 0 12 6 206 18 ptg000012l:4909030-4939389 Q9UEW3 2.7e-24 Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2) Homo sapiens (Human) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; amyloid-beta clearance [GO:0097242]; apoptotic cell clearance [GO:0043277]; cell surface receptor signaling pathway [GO:0007166]; endocytosis [GO:0006897]; innate immune response [GO:0045087]; phagocytosis, engulfment [GO:0006911]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of protein phosphorylation [GO:0001934]; receptor-mediated endocytosis [GO:0006898] GO:0001540; GO:0001664; GO:0001934; GO:0004888; GO:0005044; GO:0005581; GO:0005737; GO:0005886; GO:0006897; GO:0006898; GO:0006911; GO:0007166; GO:0007193; GO:0030666; GO:0038024; GO:0038187; GO:0043277; GO:0045087; GO:0070374; GO:0097242 26288 FUN_027926 227 62 105 109 294 NA NA NA NA NA NA NA 26289 FUN_027927 406 569 255 547 535 NA NA NA NA NA NA NA 26290 FUN_027920 0 0 0 33 32 ptg000021l:13258207-13272416 Q99315 4.72e-72 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 26291 FUN_027921 0 0 0 16 93 NA NA NA NA NA NA NA 26292 FUN_027922 28 0 0 99 79 NA NA NA NA NA NA NA 26293 FUN_027923 265 231 99 214 132 NA NA NA NA NA NA NA 26294 FUN_025566 171 68 46 68 191 NA NA NA NA NA NA NA 26295 FUN_025567 190 196 195 177 216 NA NA NA NA NA NA NA 26296 FUN_025564 5899 3960 3130 4665 4108 ptg000019l:4492061-4509482 P35605 1.46e-29 Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0005080; GO:0005198; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126; GO:1901998 26297 FUN_025564 5899 3960 3130 4665 4108 ptg000019l:4492061-4509482 P35605 1.46e-29 Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0005080; GO:0005198; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126; GO:1901998 26298 FUN_025564 5899 3960 3130 4665 4108 ptg000019l:4492061-4509482 P35605 5.22e-21 Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102) Bos taurus (Bovine) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; toxin transport [GO:1901998] GO:0000139; GO:0005080; GO:0005198; GO:0005794; GO:0005829; GO:0006886; GO:0006888; GO:0006890; GO:0006891; GO:0030126; GO:1901998 26299 FUN_025565 95 94 81 87 44 NA NA NA NA NA NA NA 26300 FUN_025562 3 0 26 0 106 NA NA NA NA NA NA NA 26301 FUN_025563 0 2 4 0 70 NA NA NA NA NA NA NA 26302 FUN_025560 14 11 0 5 34 NA NA NA NA NA NA NA 26303 FUN_025561 548 206 93 428 183 ptg000019l:4462477-4463356 Q6VFT6 2.02e-57 Forkhead box protein L2 Sus scrofa (Pig) anatomical structure morphogenesis [GO:0009653]; apoptotic DNA fragmentation [GO:0006309]; cell differentiation [GO:0030154]; embryonic eye morphogenesis [GO:0048048]; extraocular skeletal muscle development [GO:0002074]; female somatic sex determination [GO:0019101]; granulosa cell differentiation [GO:0060014]; ovarian follicle development [GO:0001541]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001541; GO:0002074; GO:0003677; GO:0003700; GO:0005634; GO:0006309; GO:0006357; GO:0009653; GO:0019101; GO:0030154; GO:0043028; GO:0043065; GO:0043280; GO:0045893; GO:0045944; GO:0048048; GO:0060014 26304 FUN_025568 11 27 0 7 61 NA NA NA NA NA NA NA 26305 FUN_025569 1460 1647 1259 1764 716 NA NA NA NA NA NA NA 26306 FUN_022943 8 12 0 1 3 NA NA NA NA NA NA NA 26307 FUN_022942 283 197 51 229 520 NA NA NA NA NA NA NA 26308 FUN_022084 0 0 11 0 27 NA NA NA NA NA NA NA 26309 FUN_029981 0 2 2 0 102 NA NA NA NA NA NA NA 26310 FUN_019231 7 0 19 0 15 ptg000012l:19916951-19917329 P35067 4.71e-81 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26311 FUN_019230 82 0 78 0 143 ptg000012l:19915472-19915883 P84239 6.31e-91 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26312 FUN_019233 9 0 14 0 17 NA NA NA NA NA NA NA 26313 FUN_019232 15 0 27 0 61 ptg000012l:19919726-19920104 P35067 2.07e-81 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26314 FUN_019238 7 0 6 7 21 NA NA NA NA NA NA NA 26315 FUN_023502 1885 1424 967 1610 921 NA NA NA NA NA NA NA 26316 FUN_023503 444 335 103 317 520 NA NA NA NA NA NA NA 26317 FUN_035804 636 321 365 981 966 NA NA NA NA NA NA NA 26318 FUN_026754 0 0 0 0 10 NA NA NA NA NA NA NA 26319 FUN_005920 847 393 70 1871 606 NA NA NA NA NA NA NA 26320 FUN_005921 1248 826 29 1200 835 NA NA NA NA NA NA NA 26321 FUN_005923 1455 559 1278 2061 982 ptg000001l:5786732-5804003 O88575 6.22e-32 Sodium- and chloride-dependent transporter XTRP3B (IMINO-K) (Solute carrier family 6 member 20B) Mus musculus (Mouse) amino acid transport [GO:0006865]; glycine import across plasma membrane [GO:1903804]; glycine transport [GO:0015816]; L-proline import across plasma membrane [GO:1904271]; proline import across plasma membrane [GO:1905647]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] GO:0005298; GO:0005886; GO:0006865; GO:0015171; GO:0015175; GO:0015193; GO:0015370; GO:0015816; GO:0015824; GO:0016324; GO:0031526; GO:0035725; GO:1903804; GO:1904271; GO:1905647 26322 FUN_005925 0 0 13 7 0 NA NA NA NA NA NA NA 26323 FUN_005929 0 0 155 0 24 NA NA NA NA NA NA NA 26324 FUN_021609 525 289 323 777 232 ptg000016l:2590368-2599857 Q95ZJ1 2.01e-35 Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) Caenorhabditis elegans protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018243; GO:0030246; GO:0046872 26325 FUN_021609 525 289 323 777 232 ptg000016l:2590368-2599857 Q95ZJ1 6.89e-27 Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) Caenorhabditis elegans protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018243; GO:0030246; GO:0046872 26326 FUN_015558 11 29 14 2 31 NA NA NA NA NA NA NA 26327 FUN_015559 13 3 1 4 0 NA NA NA NA NA NA NA 26328 FUN_022456 0 0 0 0 16 NA NA NA NA NA NA NA 26329 FUN_035668 980 1351 852 1475 1309 NA NA NA NA NA NA NA 26330 FUN_035669 1287 1267 732 842 909 NA NA NA NA NA NA NA 26331 FUN_022454 421 237 93 372 261 NA NA NA NA NA NA NA 26332 FUN_035660 127 0 42 45 39 NA NA NA NA NA NA NA 26333 FUN_035661 0 10 0 5 0 NA NA NA NA NA NA NA 26334 FUN_035662 912 941 320 521 562 NA NA NA NA NA NA NA 26335 FUN_035663 3777 3159 2217 3187 1818 ptg000025l:10445177-10454878 O54972 1.58e-29 Protein CBFA2T3 (Eight twenty one protein 2) (MTG8-related protein 2) (Protein ETO-2) Mus musculus (Mouse) granulocyte differentiation [GO:0030851]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of glycolytic process [GO:0045820]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; regulation of aerobic respiration [GO:1903715]; response to hypoxia [GO:0001666] GO:0000122; GO:0000139; GO:0001666; GO:0003682; GO:0003714; GO:0005634; GO:0005654; GO:0005730; GO:0008285; GO:0030851; GO:0032436; GO:0045820; GO:0045892; GO:0046872; GO:1903715 26336 FUN_035664 22 0 12 0 10 NA NA NA NA NA NA NA 26337 FUN_035665 2146 1796 826 3074 2034 ptg000025l:10473942-10482742 Q9NRH2 2.52e-89 SNF-related serine/threonine-protein kinase (EC 2.7.11.1) (SNF1-related kinase) Homo sapiens (Human) intracellular signal transduction [GO:0035556]; myeloid cell differentiation [GO:0030099]; protein phosphorylation [GO:0006468] GO:0000287; GO:0004674; GO:0005524; GO:0005634; GO:0006468; GO:0030099; GO:0035556; GO:0106310 26338 FUN_035666 624 523 309 293 417 NA NA NA NA NA NA NA 26339 FUN_015553 0 4 13 0 0 NA NA NA NA NA NA NA 26340 FUN_020008 10 0 0 0 0 NA NA NA NA NA NA NA 26341 FUN_016174 1 0 3 4 9 NA NA NA NA NA NA NA 26342 FUN_043288 3250 3351 893 2704 772 NA NA NA NA NA NA NA 26343 FUN_008342 60 33 0 0 55 ptg000002l:10587492-10588905 B3EX02 1.08e-31 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 26344 FUN_001713 4 0 0 0 20 NA NA NA NA NA NA NA 26345 FUN_001712 32 0 2 4 218 NA NA NA NA NA NA NA 26346 FUN_001716 0 0 0 0 7 NA NA NA NA NA NA NA 26347 FUN_001715 129 80 21 43 159 NA NA NA NA NA NA NA 26348 FUN_001714 81 10 33 69 84 NA NA NA NA NA NA NA 26349 FUN_001719 0 0 0 0 17 NA NA NA NA NA NA NA 26350 FUN_001718 44 0 0 0 21 NA NA NA NA NA NA NA 26351 FUN_043822 0 0 0 0 7 NA NA NA NA NA NA NA 26352 FUN_043821 22 0 2 0 4 NA NA NA NA NA NA NA 26353 FUN_043820 0 0 0 0 11 NA NA NA NA NA NA NA 26354 FUN_043829 2 1 1 9 4 NA NA NA NA NA NA NA 26355 FUN_043828 0 8 6 2 82 NA NA NA NA NA NA NA 26356 FUN_041753 466 271 331 472 587 NA NA NA NA NA NA NA 26357 FUN_036314 0 0 0 0 44 NA NA NA NA NA NA NA 26358 FUN_036317 752 39 0 54 0 NA NA NA NA NA NA NA 26359 FUN_007650 12 0 0 10 16 NA NA NA NA NA NA NA 26360 FUN_007651 54 0 4 0 123 ptg000002l:2903997-2915695 Q2EG98 5.57e-32 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 26361 FUN_007652 48 16 3 32 12 ptg000002l:2916222-2918099 A2A259 3.42e-37 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to pH [GO:0071467]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0034703; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051262; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071467; GO:0071468; GO:0071805; GO:0097730; GO:0098662 26362 FUN_007653 0 0 15 62 15 ptg000002l:2923255-2930730 Q7TN88 1.43e-34 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 26363 FUN_007654 39 0 0 25 50 NA NA NA NA NA NA NA 26364 FUN_004998 38 0 0 0 191 NA NA NA NA NA NA NA 26365 FUN_041752 2566 1817 726 1880 1003 NA NA NA NA NA NA NA 26366 FUN_000390 3059 1628 1718 2456 1351 NA NA NA NA NA NA NA 26367 FUN_000391 973 501 553 245 365 NA NA NA NA NA NA NA 26368 FUN_000392 863 472 217 308 284 NA NA NA NA NA NA NA 26369 FUN_000393 50145 53884 26824 47749 35612 ntLink_6:2373597-2379181 P02385 7.38e-40 60S ribosomal protein L4-B (L1B) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 26370 FUN_000393 50145 53884 26824 47749 35612 ntLink_6:2373597-2379181 P02385 6.27e-26 60S ribosomal protein L4-B (L1B) Xenopus laevis (African clawed frog) translation [GO:0006412] GO:0003735; GO:0005737; GO:0005840; GO:0006412; GO:1990904 26371 FUN_000394 2563 2185 910 1984 1212 NA NA NA NA NA NA NA 26372 FUN_000395 1140 1345 759 1307 1004 NA NA NA NA NA NA NA 26373 FUN_000396 7803 6131 3420 7813 5284 ntLink_6:2386551-2392800 Q8VIF7 8.57e-23 Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) (Selenium-binding protein 2) Rattus norvegicus (Rat) brown fat cell differentiation [GO:0050873]; protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549; GO:0050873 26374 FUN_000397 901 417 509 957 1044 ntLink_6:2394684-2407098 Q69Z38 9.89e-29 Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269) Mus musculus (Mouse) cell migration [GO:0016477]; focal adhesion assembly [GO:0048041]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of focal adhesion assembly [GO:0051893]; substrate adhesion-dependent cell spreading [GO:0034446] GO:0004672; GO:0004715; GO:0005737; GO:0005925; GO:0006468; GO:0015629; GO:0016477; GO:0034446; GO:0042802; GO:0046777; GO:0048041; GO:0051893 26375 FUN_000398 8564 12197 11536 10729 4911 NA NA NA NA NA NA NA 26376 FUN_000399 3858 4703 1810 2297 1992 NA NA NA NA NA NA NA 26377 FUN_041751 1796 858 764 1355 771 ptg000035l:7140365-7145124 P23416 4.25e-31 Glycine receptor subunit alpha-2 Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007218; GO:0007268; GO:0016594; GO:0016934; GO:0022852; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0045202; GO:0045211; GO:0046872; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:0098690; GO:1902476; GO:1904315 26378 FUN_033365 1 0 1 0 7 NA NA NA NA NA NA NA 26379 FUN_005068 69 0 145 502 120 NA NA NA NA NA NA NA 26380 FUN_016815 4 0 8 44 30 ptg000011l:7802677-7824353 O70165 1.6e-41 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 26381 FUN_016816 13 7 0 0 21 NA NA NA NA NA NA NA 26382 FUN_016817 0 0 0 0 20 NA NA NA NA NA NA NA 26383 FUN_016812 0 0 0 0 13 NA NA NA NA NA NA NA 26384 FUN_016813 0 141 0 0 34 ptg000011l:7780911-7781859 R1CW23 1.51e-95 Dimethylsulfonioproprionate lyase 7 (DMSP lyase 7) (EC 4.4.1.3) (Dimethylpropiothetin dethiomethylase 7) Emiliania huxleyi (Coccolithophore) (Pontosphaera huxleyi) NA GO:0047869 26385 FUN_033095 0 0 2 12 28 NA NA NA NA NA NA NA 26386 FUN_033094 2 0 35 0 67 NA NA NA NA NA NA NA 26387 FUN_033091 0 0 0 0 10 NA NA NA NA NA NA NA 26388 FUN_033093 4 0 0 0 101 NA NA NA NA NA NA NA 26389 FUN_033092 12 0 0 40 13 ptg000023l:39870322-39878682 Q96DM1 4.41e-24 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 26390 FUN_006529 0 0 29 56 0 NA NA NA NA NA NA NA 26391 FUN_006528 16 13 0 0 0 NA NA NA NA NA NA NA 26392 FUN_008549 2316 1502 923 1739 1941 ptg000002l:12828139-12836778 B2RRD7 1.04e-149 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 26393 FUN_008549 2316 1502 923 1739 1941 ptg000002l:12828139-12836778 B2RRD7 1.11e-21 Peregrin (Bromodomain and PHD finger-containing protein 1) Mus musculus (Mouse) chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; histone H3-K23 acetylation [GO:0043972]; neural tube formation [GO:0001841]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculogenesis [GO:0001570] GO:0000123; GO:0001570; GO:0001841; GO:0003677; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0006325; GO:0006355; GO:0006357; GO:0010698; GO:0035726; GO:0043972; GO:0043995; GO:0043996; GO:0043997; GO:0045893; GO:0046872; GO:0048145; GO:0070776 26394 FUN_008548 1235 473 576 842 1122 NA NA NA NA NA NA NA 26395 FUN_006521 0 0 0 25 0 ptg000001l:13583696-13591126 Q7RTR2 2.18e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26396 FUN_006521 0 0 0 25 0 ptg000001l:13583696-13591126 Q7RTR2 3.85e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26397 FUN_008544 13944 7204 5510 12214 8538 NA NA NA NA NA NA NA 26398 FUN_006522 0 0 0 5 15 NA NA NA NA NA NA NA 26399 FUN_006525 2 24 0 442 77 NA NA NA NA NA NA NA 26400 FUN_008540 1420 655 335 1375 936 ptg000002l:12671800-12693133 D3YXG0 2.66e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26401 FUN_008540 1420 655 335 1375 936 ptg000002l:12671800-12693133 D3YXG0 2.66e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 26402 FUN_008543 3909 2917 1243 3725 2412 NA NA NA NA NA NA NA 26403 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 1.3e-77 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26404 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 2.1e-77 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26405 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 1.14e-75 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26406 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 1.29e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26407 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 2.76e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26408 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 5.27e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26409 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 8.4e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26410 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 6.66e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26411 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 3.87e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26412 FUN_006526 873 563 71 2085 599 ptg000001l:13623924-13631463 Q7RTR2 4.13e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 26413 FUN_001154 354 165 204 205 272 ntLink_6:9185627-9187960 Q5RF73 4.45e-54 Transmembrane protein 19 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0016020 26414 FUN_042888 1159 7196 642 2822 4743 NA NA NA NA NA NA NA 26415 FUN_042886 233 317 143 229 292 NA NA NA NA NA NA NA 26416 FUN_042887 934 2106 340 995 1864 NA NA NA NA NA NA NA 26417 FUN_042884 162 153 20 54 161 NA NA NA NA NA NA NA 26418 FUN_042885 1012 949 340 769 1309 ptg000047l:1300794-1310042 Q63HN8 3.58e-39 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 26419 FUN_042882 71 251 49 42 425 NA NA NA NA NA NA NA 26420 FUN_042883 78 163 29 18 182 NA NA NA NA NA NA NA 26421 FUN_042880 0 21 0 0 73 NA NA NA NA NA NA NA 26422 FUN_042881 0 185 8 4 173 NA NA NA NA NA NA NA 26423 FUN_004673 127 49 57 144 138 NA NA NA NA NA NA NA 26424 FUN_004670 233 87 127 137 73 NA NA NA NA NA NA NA 26425 FUN_004677 516 252 278 517 339 NA NA NA NA NA NA NA 26426 FUN_004674 133 129 62 8 17 NA NA NA NA NA NA NA 26427 FUN_040035 238 203 186 225 251 NA NA NA NA NA NA NA 26428 FUN_040034 297 108 23 171 113 NA NA NA NA NA NA NA 26429 FUN_004679 673 474 447 271 374 NA NA NA NA NA NA NA 26430 FUN_004678 106 10 92 45 110 NA NA NA NA NA NA NA 26431 FUN_040031 2293 1543 1164 2104 1678 ptg000031l:3266482-3324334 Q8C1B2 1.89e-39 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 26432 FUN_040031 2293 1543 1164 2104 1678 ptg000031l:3266482-3324334 Q8C1B2 1.54e-37 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 26433 FUN_041754 4621 3580 2118 3056 2503 NA NA NA NA NA NA NA 26434 FUN_032949 0 0 0 0 12 NA NA NA NA NA NA NA 26435 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 4.75e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26436 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 1.69e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26437 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 7.17e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26438 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 7.09e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26439 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 2.1e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26440 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 2.8e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26441 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 2.28e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26442 FUN_032941 26 35 0 50 133 ptg000023l:37909774-37913087 Q96AY4 1.97e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26443 FUN_032942 13 0 0 1 53 NA NA NA NA NA NA NA 26444 FUN_032943 31 25 23 4 72 NA NA NA NA NA NA NA 26445 FUN_032944 291 32 11 57 16 NA NA NA NA NA NA NA 26446 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 3.95e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26447 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 2.44e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26448 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 4.88e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26449 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 2.66e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26450 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 2.52e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26451 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 3.41e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26452 FUN_032947 80 53 9 24 22 ptg000023l:37946469-37951937 Q96AY4 3.24e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26453 FUN_002536 561 667 0 770 153 NA NA NA NA NA NA NA 26454 FUN_002534 1862 626 119 935 106 NA NA NA NA NA NA NA 26455 FUN_011046 676 898 518 658 851 ptg000007l:5729474-5784540 Q95SX7 3.06e-36 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26456 FUN_011047 19 0 4 0 0 NA NA NA NA NA NA NA 26457 FUN_011048 1805 1152 1064 1697 1161 ptg000007l:5788012-5802584 Q5PQT2 1.01e-23 Myotubularin-related protein 3 (EC 3.1.3.48) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Rattus norvegicus (Rat) cellular response to glucose starvation [GO:0042149]; phosphatidylinositol 5-phosphate metabolic process [GO:1904562]; phosphatidylinositol dephosphorylation [GO:0046856]; protein dephosphorylation [GO:0006470]; regulation of autophagosome assembly [GO:2000785]; regulation of autophagy [GO:0010506]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0004722; GO:0004725; GO:0005737; GO:0006470; GO:0008138; GO:0010506; GO:0016020; GO:0019898; GO:0019903; GO:0042149; GO:0046856; GO:0046872; GO:0052629; GO:0060304; GO:1904562; GO:2000785 26458 FUN_011049 11705 9679 6500 8954 6856 NA NA NA NA NA NA NA 26459 FUN_002539 595 415 463 742 867 NA NA NA NA NA NA NA 26460 FUN_012227 0 6 20 0 71 NA NA NA NA NA NA NA 26461 FUN_012226 4316 415 1019 904 936 ptg000008l:6535177-6540050 Q92058 4.18e-23 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNSALP) (EC 3.1.3.1) (Phosphoamidase) Gallus gallus (Chicken) bone mineralization [GO:0030282]; dephosphorylation [GO:0016311]; positive regulation of cold-induced thermogenesis [GO:0120162] GO:0004035; GO:0004427; GO:0005509; GO:0005758; GO:0005886; GO:0016311; GO:0016462; GO:0016887; GO:0030282; GO:0033883; GO:0043262; GO:0050187; GO:0052732; GO:0065010; GO:0120162 26462 FUN_012225 31 19 17 27 135 ptg000008l:6525989-6529750 P05186 3.09e-24 Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNS-ALP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase liver/bone/kidney isozyme) (Phosphoamidase) (Phosphocreatine phosphatase) (EC 3.9.1.1) Homo sapiens (Human) bone mineralization [GO:0030282]; calcium ion homeostasis [GO:0055074]; cellular homeostasis [GO:0019725]; cellular response to organic cyclic compound [GO:0071407]; cementum mineralization [GO:0071529]; dephosphorylation [GO:0016311]; developmental process involved in reproduction [GO:0003006]; endochondral ossification [GO:0001958]; multicellular organism aging [GO:0010259]; osteoblast differentiation [GO:0001649]; phosphate ion homeostasis [GO:0055062]; positive regulation of cold-induced thermogenesis [GO:0120162]; pyridoxal phosphate metabolic process [GO:0042822]; response to antibiotic [GO:0046677]; response to glucocorticoid [GO:0051384]; response to insulin [GO:0032868]; response to lipopolysaccharide [GO:0032496]; response to macrophage colony-stimulating factor [GO:0036005]; response to sodium phosphate [GO:1904383]; response to vitamin B6 [GO:0034516]; response to vitamin D [GO:0033280]; skeletal system development [GO:0001501] GO:0001501; GO:0001649; GO:0001958; GO:0003006; GO:0004035; GO:0004427; GO:0005509; GO:0005576; GO:0005758; GO:0005886; GO:0010259; GO:0016020; GO:0016311; GO:0016462; GO:0016887; GO:0019725; GO:0030282; GO:0031012; GO:0031966; GO:0032496; GO:0032868; GO:0033280; GO:0033883; GO:0034516; GO:0036005; GO:0042822; GO:0043262; GO:0046677; GO:0050187; GO:0051384; GO:0052732; GO:0055062; GO:0055074; GO:0070062; GO:0071407; GO:0071529; GO:0120162; GO:1904383 26463 FUN_012224 21 11 3 88 161 NA NA NA NA NA NA NA 26464 FUN_012223 1019 1055 618 1429 1345 NA NA NA NA NA NA NA 26465 FUN_012222 868 630 589 585 281 NA NA NA NA NA NA NA 26466 FUN_012221 431 229 97 445 371 NA NA NA NA NA NA NA 26467 FUN_012220 0 28 0 24 14 NA NA NA NA NA NA NA 26468 FUN_012229 87 47 106 90 95 ptg000008l:6561269-6569622 Q64104 4.93e-36 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (mTll) Mus musculus (Mouse) aggressive behavior [GO:0002118]; amygdala development [GO:0021764]; anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; anterior commissure morphogenesis [GO:0021960]; apoptotic process [GO:0006915]; astrocyte cell migration [GO:0043615]; astrocyte differentiation [GO:0048708]; behavioral fear response [GO:0001662]; brain development [GO:0007420]; camera-type eye development [GO:0043010]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; cerebral cortex neuron differentiation [GO:0021895]; dentate gyrus development [GO:0021542]; extracellular matrix organization [GO:0030198]; forebrain generation of neurons [GO:0021872]; layer formation in cerebral cortex [GO:0021819]; long-term synaptic potentiation [GO:0060291]; negative regulation of apoptotic process [GO:0043066]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural precursor cell proliferation [GO:0061351]; neuroblast proliferation [GO:0007405]; neuron differentiation [GO:0030182]; olfactory bulb development [GO:0021772]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of stem cell proliferation [GO:2000648]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of cellular component organization [GO:0051128]; regulation of dendrite morphogenesis [GO:0048814]; regulation of timing of neuron differentiation [GO:0060164]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041]; social behavior [GO:0035176]; somatic stem cell population maintenance [GO:0035019]; visual perception [GO:0007601] GO:0000122; GO:0000978; GO:0001227; GO:0001228; GO:0001525; GO:0001662; GO:0002052; GO:0002118; GO:0004879; GO:0005634; GO:0005654; GO:0006357; GO:0006915; GO:0007405; GO:0007420; GO:0007601; GO:0008270; GO:0008283; GO:0008284; GO:0019899; GO:0021542; GO:0021764; GO:0021772; GO:0021819; GO:0021872; GO:0021895; GO:0021960; GO:0021987; GO:0030154; GO:0030182; GO:0030198; GO:0035019; GO:0035176; GO:0042826; GO:0043010; GO:0043066; GO:0043615; GO:0045165; GO:0045665; GO:0045766; GO:0045787; GO:0048708; GO:0048712; GO:0048814; GO:0048856; GO:0051128; GO:0060041; GO:0060164; GO:0060291; GO:0061351; GO:0090049; GO:1990837; GO:2000178; GO:2000179; GO:2000648 26469 FUN_012229 87 47 106 90 95 ptg000008l:6561269-6569622 Q64104 2.13e-22 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) (mTll) Mus musculus (Mouse) aggressive behavior [GO:0002118]; amygdala development [GO:0021764]; anatomical structure development [GO:0048856]; angiogenesis [GO:0001525]; anterior commissure morphogenesis [GO:0021960]; apoptotic process [GO:0006915]; astrocyte cell migration [GO:0043615]; astrocyte differentiation [GO:0048708]; behavioral fear response [GO:0001662]; brain development [GO:0007420]; camera-type eye development [GO:0043010]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; cerebral cortex neuron differentiation [GO:0021895]; dentate gyrus development [GO:0021542]; extracellular matrix organization [GO:0030198]; forebrain generation of neurons [GO:0021872]; layer formation in cerebral cortex [GO:0021819]; long-term synaptic potentiation [GO:0060291]; negative regulation of apoptotic process [GO:0043066]; negative regulation of astrocyte differentiation [GO:0048712]; negative regulation of neural precursor cell proliferation [GO:2000178]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural precursor cell proliferation [GO:0061351]; neuroblast proliferation [GO:0007405]; neuron differentiation [GO:0030182]; olfactory bulb development [GO:0021772]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell cycle [GO:0045787]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of neuroblast proliferation [GO:0002052]; positive regulation of stem cell proliferation [GO:2000648]; regulation of cell migration involved in sprouting angiogenesis [GO:0090049]; regulation of cellular component organization [GO:0051128]; regulation of dendrite morphogenesis [GO:0048814]; regulation of timing of neuron differentiation [GO:0060164]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041]; social behavior [GO:0035176]; somatic stem cell population maintenance [GO:0035019]; visual perception [GO:0007601] GO:0000122; GO:0000978; GO:0001227; GO:0001228; GO:0001525; GO:0001662; GO:0002052; GO:0002118; GO:0004879; GO:0005634; GO:0005654; GO:0006357; GO:0006915; GO:0007405; GO:0007420; GO:0007601; GO:0008270; GO:0008283; GO:0008284; GO:0019899; GO:0021542; GO:0021764; GO:0021772; GO:0021819; GO:0021872; GO:0021895; GO:0021960; GO:0021987; GO:0030154; GO:0030182; GO:0030198; GO:0035019; GO:0035176; GO:0042826; GO:0043010; GO:0043066; GO:0043615; GO:0045165; GO:0045665; GO:0045766; GO:0045787; GO:0048708; GO:0048712; GO:0048814; GO:0048856; GO:0051128; GO:0060041; GO:0060164; GO:0060291; GO:0061351; GO:0090049; GO:1990837; GO:2000178; GO:2000179; GO:2000648 26470 FUN_012228 0 7 0 0 0 NA NA NA NA NA NA NA 26471 FUN_013574 749 690 439 672 1430 ptg000008l:24164946-24166023 Q7ZVH1 8.5e-43 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 26472 FUN_013575 565 2734 732 228 1417 NA NA NA NA NA NA NA 26473 FUN_013576 1286 2806 851 334 1181 NA NA NA NA NA NA NA 26474 FUN_013570 1637 1324 914 876 764 NA NA NA NA NA NA NA 26475 FUN_013571 261 344 134 535 231 NA NA NA NA NA NA NA 26476 FUN_013572 280 158 282 449 331 ptg000008l:24157199-24160761 Q9TRC7 5.95e-142 Amiloride-sensitive amine oxidase [copper-containing] (DAO) (Diamine oxidase) (EC 1.4.3.22) (Amiloride-binding protein 1) (Amine oxidase copper domain-containing protein 1) (Histaminase) Sus scrofa (Pig) amine metabolic process [GO:0009308]; cellular response to azide [GO:0097185]; cellular response to copper ion [GO:0071280]; cellular response to copper ion starvation [GO:0035874]; cellular response to histamine [GO:0071420]; putrescine metabolic process [GO:0009445]; response to antibiotic [GO:0046677] GO:0005507; GO:0005509; GO:0005615; GO:0005886; GO:0005923; GO:0008131; GO:0008201; GO:0008270; GO:0009308; GO:0009445; GO:0035874; GO:0042803; GO:0044877; GO:0046677; GO:0048038; GO:0052597; GO:0052598; GO:0052599; GO:0052600; GO:0070062; GO:0071280; GO:0071420; GO:0097185 26477 FUN_013573 556 215 122 213 174 ptg000008l:24161733-24164143 Q7ZVH1 2.89e-39 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 26478 FUN_013578 812 790 393 681 739 NA NA NA NA NA NA NA 26479 FUN_013579 354 398 271 444 374 NA NA NA NA NA NA NA 26480 FUN_029298 358 387 138 309 436 NA NA NA NA NA NA NA 26481 FUN_029299 2084 1152 663 1389 1312 NA NA NA NA NA NA NA 26482 FUN_029290 1025 621 599 797 1073 ptg000023l:61420-86928 O35134 2.55e-47 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Mus musculus (Mouse) negative regulation of protein localization to nucleolus [GO:1904750]; rRNA transcription [GO:0009303] GO:0001054; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005694; GO:0005736; GO:0009303; GO:0046872; GO:1904750 26483 FUN_029290 1025 621 599 797 1073 ptg000023l:61420-86928 O35134 1.68e-27 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Mus musculus (Mouse) negative regulation of protein localization to nucleolus [GO:1904750]; rRNA transcription [GO:0009303] GO:0001054; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005694; GO:0005736; GO:0009303; GO:0046872; GO:1904750 26484 FUN_029290 1025 621 599 797 1073 ptg000023l:61420-86928 O35134 4.59e-26 DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) Mus musculus (Mouse) negative regulation of protein localization to nucleolus [GO:1904750]; rRNA transcription [GO:0009303] GO:0001054; GO:0003677; GO:0003682; GO:0003899; GO:0005634; GO:0005654; GO:0005694; GO:0005736; GO:0009303; GO:0046872; GO:1904750 26485 FUN_029291 5601 3248 2589 5762 6229 NA NA NA NA NA NA NA 26486 FUN_029292 3062 1810 1997 7782 3435 NA NA NA NA NA NA NA 26487 FUN_029293 6570 2823 1089 1036 4826 NA NA NA NA NA NA NA 26488 FUN_029296 862 694 447 1495 1528 NA NA NA NA NA NA NA 26489 FUN_029297 205 180 124 226 156 ptg000023l:199109-201062 Q29AK2 7.66e-177 Leishmanolysin-like peptidase (EC 3.4.24.-) Drosophila pseudoobscura pseudoobscura (Fruit fly) brain development [GO:0007420]; cell adhesion [GO:0007155]; cell division [GO:0051301]; centrosome duplication [GO:0051298]; chromatin remodeling [GO:0006338]; electron transport chain [GO:0022900]; germ cell migration [GO:0008354]; gonad development [GO:0008406]; imaginal disc development [GO:0007444]; lipid storage [GO:0019915]; mitotic centrosome separation [GO:0007100]; mitotic chromosome condensation [GO:0007076]; mitotic spindle organization [GO:0007052]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; proteolysis [GO:0006508]; regulation of choline O-acetyltransferase activity [GO:1902769] GO:0004222; GO:0005737; GO:0006338; GO:0006508; GO:0007052; GO:0007076; GO:0007100; GO:0007155; GO:0007420; GO:0007444; GO:0008233; GO:0008354; GO:0008406; GO:0016020; GO:0019915; GO:0022900; GO:0045842; GO:0046872; GO:0051298; GO:0051301; GO:1902769 26490 FUN_009626 0 0 0 121 6 NA NA NA NA NA NA NA 26491 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.16e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26492 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.26e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26493 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 6.68e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26494 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 8.13e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26495 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 2.59e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26496 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.3e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26497 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.5e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26498 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 3.6e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26499 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 4.34e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26500 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 6.64e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26501 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 4.05e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26502 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 6.89e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26503 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 3.94e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26504 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 2.43e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26505 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 3.25e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26506 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 5.44e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26507 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.65e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26508 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.59e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26509 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.81e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26510 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.7e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26511 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 1.09e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26512 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 5.44e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26513 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 4.05e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26514 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 2.3e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26515 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 7.37e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26516 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 7.94e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26517 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 9.55e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26518 FUN_009625 25 42 38 249 28 ptg000004l:9573682-9642800 Q96AY4 2.72e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26519 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 2.44e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26520 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 1.65e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26521 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 7.58e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26522 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 3.02e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26523 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 8.33e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26524 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 1.73e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26525 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 4.38e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26526 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 1.11e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26527 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 3.56e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26528 FUN_009624 61 0 0 52 65 ptg000004l:9551262-9555174 Q96AY4 1.37e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26529 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.11e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26530 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.32e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26531 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.2e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26532 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 5.68e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26533 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 7.74e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26534 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.12e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26535 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.19e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26536 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 3.37e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26537 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 4.62e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26538 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.27e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26539 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.12e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26540 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 8.41e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26541 FUN_009623 24 5 15 57 67 ptg000004l:9510496-9516233 Q96AY4 1.56e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26542 FUN_009622 41 10 24 88 36 NA NA NA NA NA NA NA 26543 FUN_009621 0 2 2 4 9 NA NA NA NA NA NA NA 26544 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 1.27e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26545 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 1.04e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26546 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 2.74e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26547 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 2.09e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26548 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 1.15e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26549 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 7.38e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26550 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 1.11e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26551 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 9.31e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26552 FUN_009620 4187 486 559 861 1640 ptg000004l:9467921-9470612 Q96AY4 3.28e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26553 FUN_009629 40 7 22 108 55 ptg000004l:9672034-9680010 Q96AY4 5.84e-162 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26554 FUN_009629 40 7 22 108 55 ptg000004l:9672034-9680010 Q96AY4 9.09e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26555 FUN_009629 40 7 22 108 55 ptg000004l:9672034-9680010 Q96AY4 1.21e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26556 FUN_009629 40 7 22 108 55 ptg000004l:9672034-9680010 Q96AY4 1.88e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26557 FUN_009629 40 7 22 108 55 ptg000004l:9672034-9680010 Q96AY4 2.22e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26558 FUN_009629 40 7 22 108 55 ptg000004l:9672034-9680010 Q96AY4 2.43e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26559 FUN_009628 4 185 1 177 2 NA NA NA NA NA NA NA 26560 FUN_012483 263 287 44 317 61 NA NA NA NA NA NA NA 26561 FUN_012482 1744 1381 477 1463 892 NA NA NA NA NA NA NA 26562 FUN_012481 4269 2400 2122 1784 544 NA NA NA NA NA NA NA 26563 FUN_012480 1597 3188 2697 2558 3569 NA NA NA NA NA NA NA 26564 FUN_012487 0 13 0 7 0 NA NA NA NA NA NA NA 26565 FUN_012486 187 312 53 471 148 NA NA NA NA NA NA NA 26566 FUN_012485 744 684 372 701 791 NA NA NA NA NA NA NA 26567 FUN_012484 136 137 49 163 76 NA NA NA NA NA NA NA 26568 FUN_012489 0 0 0 0 6 NA NA NA NA NA NA NA 26569 FUN_012488 1398 1203 1180 1116 1339 NA NA NA NA NA NA NA 26570 FUN_004127 299 93 154 133 146 ntLink_8:19593867-19598282 Q19291 6.47e-24 Doublesex- and mab-3-related transcription factor dmd-5 Caenorhabditis elegans male anatomical structure morphogenesis [GO:0090598]; negative regulation of synapse pruning [GO:1905807]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007548; GO:0046872; GO:0090598; GO:1905807 26571 FUN_010885 5249 4212 2011 9241 9368 NA NA NA NA NA NA NA 26572 FUN_010887 3794 2570 2008 3246 3412 ptg000007l:3963227-3974708 Q32LP2 9.15e-23 Radixin Bos taurus (Bovine) actin filament capping [GO:0051693]; establishment of endothelial barrier [GO:0061028]; negative regulation of adherens junction organization [GO:1903392]; negative regulation of cell size [GO:0045792]; negative regulation of GTPase activity [GO:0034260]; negative regulation of homotypic cell-cell adhesion [GO:0034111]; positive regulation of cell migration [GO:0030335]; positive regulation of early endosome to late endosome transport [GO:2000643]; positive regulation of gene expression [GO:0010628]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of protein localization to early endosome [GO:1902966]; protein localization to plasma membrane [GO:0072659]; regulation of actin filament bundle assembly [GO:0032231]; regulation of cell shape [GO:0008360]; regulation of organelle assembly [GO:1902115]; regulation of ruffle assembly [GO:1900027] GO:0003779; GO:0005737; GO:0005856; GO:0005886; GO:0005902; GO:0005912; GO:0005925; GO:0008360; GO:0010628; GO:0016324; GO:0030175; GO:0030335; GO:0032154; GO:0032231; GO:0034111; GO:0034260; GO:0045177; GO:0045732; GO:0045792; GO:0050839; GO:0051117; GO:0051693; GO:0061028; GO:0072659; GO:1900027; GO:1902115; GO:1902966; GO:1903392; GO:2000643 26573 FUN_010886 712 567 249 468 252 NA NA NA NA NA NA NA 26574 FUN_010881 4910 7182 4176 5373 6810 NA NA NA NA NA NA NA 26575 FUN_010880 4123 5671 4145 4589 4143 NA NA NA NA NA NA NA 26576 FUN_010883 21670 14731 9233 19242 14839 NA NA NA NA NA NA NA 26577 FUN_040364 0 65 0 0 0 NA NA NA NA NA NA NA 26578 FUN_010888 554 433 294 508 560 ptg000007l:3979468-3986387 Q969V5 1.03e-38 Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 2.3.2.27) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (Protein Hades) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218) (RING-type E3 ubiquitin transferase NFKB 1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to exogenous dsRNA [GO:0071360]; mitochondrial fission [GO:0000266]; mitochondrion localization [GO:0051646]; negative regulation of cell growth [GO:0030308]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of defense response to virus by host [GO:0050689]; negative regulation of innate immune response [GO:0045824]; negative regulation of mitochondrial fusion [GO:0010637]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization [GO:1904925]; positive regulation of dendrite extension [GO:1903861]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of mitochondrial fission [GO:0090141]; positive regulation of protein sumoylation [GO:0033235]; protein destabilization [GO:0031648]; protein polyubiquitination [GO:0000209]; protein stabilization [GO:0050821]; protein ubiquitination [GO:0016567]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway [GO:1901028]; regulation of mitochondrion organization [GO:0010821] GO:0000209; GO:0000266; GO:0002039; GO:0004842; GO:0005739; GO:0005741; GO:0005777; GO:0006915; GO:0006919; GO:0010637; GO:0010821; GO:0016020; GO:0016567; GO:0019789; GO:0030308; GO:0030424; GO:0031625; GO:0031648; GO:0033235; GO:0042802; GO:0043025; GO:0043123; GO:0045824; GO:0046872; GO:0050689; GO:0050821; GO:0051646; GO:0051881; GO:0051898; GO:0060339; GO:0061630; GO:0071360; GO:0071650; GO:0090141; GO:1901028; GO:1903861; GO:1904925 26579 FUN_040360 9 339 588 2125 85 NA NA NA NA NA NA NA 26580 FUN_016065 39 126 95 86 115 NA NA NA NA NA NA NA 26581 FUN_013686 0 0 3 0 23 NA NA NA NA NA NA NA 26582 FUN_013684 0 0 0 36 0 ptg000008l:25444782-25448122 Q95SX7 4.98e-25 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26583 FUN_013685 4 7 18 18 8 NA NA NA NA NA NA NA 26584 FUN_013680 23 4 22 17 29 NA NA NA NA NA NA NA 26585 FUN_009081 148 125 7 113 26 NA NA NA NA NA NA NA 26586 FUN_009080 8 11 5 4 14 ptg000004l:2489100-2493054 Q96AY4 1.88e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26587 FUN_009080 8 11 5 4 14 ptg000004l:2489100-2493054 Q96AY4 2.77e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26588 FUN_009080 8 11 5 4 14 ptg000004l:2489100-2493054 Q96AY4 1.34e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26589 FUN_009086 0 15 0 0 0 NA NA NA NA NA NA NA 26590 FUN_009085 5 7 5 9 11 NA NA NA NA NA NA NA 26591 FUN_009084 47 0 0 61 70 NA NA NA NA NA NA NA 26592 FUN_009089 0 2 0 14 0 NA NA NA NA NA NA NA 26593 FUN_009088 25 35 2 9 4 ptg000004l:2573428-2577529 Q96AY4 3.86e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26594 FUN_009088 25 35 2 9 4 ptg000004l:2573428-2577529 Q96AY4 3.48e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26595 FUN_009088 25 35 2 9 4 ptg000004l:2573428-2577529 Q96AY4 2.39e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26596 FUN_041415 58 7 201 5 14 NA NA NA NA NA NA NA 26597 FUN_008974 4698 4634 2322 3494 1954 NA NA NA NA NA NA NA 26598 FUN_008975 7 72 17 17 18 NA NA NA NA NA NA NA 26599 FUN_008976 510 1064 849 742 411 NA NA NA NA NA NA NA 26600 FUN_008977 32 71 23 24 46 NA NA NA NA NA NA NA 26601 FUN_008970 82 151 73 99 145 NA NA NA NA NA NA NA 26602 FUN_008971 92 37 51 82 64 NA NA NA NA NA NA NA 26603 FUN_008972 3114 1696 1538 1918 2346 NA NA NA NA NA NA NA 26604 FUN_008973 891 605 516 893 1066 NA NA NA NA NA NA NA 26605 FUN_008978 3110 2050 1041 2211 1263 NA NA NA NA NA NA NA 26606 FUN_008979 3420 2990 3670 3454 2972 ptg000004l:1073058-1079336 P18279 5.15e-34 T-complex protein 1 subunit alpha (TCP-1-alpha) (65 kDa antigen) (CCT-alpha) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; regulation of macrophage apoptotic process [GO:2000109]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] GO:0000242; GO:0000792; GO:0001669; GO:0002199; GO:0005524; GO:0005794; GO:0005832; GO:0005874; GO:0007339; GO:0016887; GO:0031625; GO:0032212; GO:0044053; GO:0044297; GO:0050821; GO:0051082; GO:0051973; GO:0061077; GO:0090666; GO:0140662; GO:1901998; GO:1904851; GO:1904874; GO:2000109 26607 FUN_008979 3420 2990 3670 3454 2972 ptg000004l:1073058-1079336 P18279 1.28e-30 T-complex protein 1 subunit alpha (TCP-1-alpha) (65 kDa antigen) (CCT-alpha) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; regulation of macrophage apoptotic process [GO:2000109]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] GO:0000242; GO:0000792; GO:0001669; GO:0002199; GO:0005524; GO:0005794; GO:0005832; GO:0005874; GO:0007339; GO:0016887; GO:0031625; GO:0032212; GO:0044053; GO:0044297; GO:0050821; GO:0051082; GO:0051973; GO:0061077; GO:0090666; GO:0140662; GO:1901998; GO:1904851; GO:1904874; GO:2000109 26608 FUN_008979 3420 2990 3670 3454 2972 ptg000004l:1073058-1079336 P18279 2.03e-25 T-complex protein 1 subunit alpha (TCP-1-alpha) (65 kDa antigen) (CCT-alpha) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) binding of sperm to zona pellucida [GO:0007339]; chaperone-mediated protein folding [GO:0061077]; positive regulation of establishment of protein localization to telomere [GO:1904851]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomerase RNA localization to Cajal body [GO:1904874]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein stabilization [GO:0050821]; regulation of macrophage apoptotic process [GO:2000109]; scaRNA localization to Cajal body [GO:0090666]; toxin transport [GO:1901998]; translocation of peptides or proteins into host cell cytoplasm [GO:0044053] GO:0000242; GO:0000792; GO:0001669; GO:0002199; GO:0005524; GO:0005794; GO:0005832; GO:0005874; GO:0007339; GO:0016887; GO:0031625; GO:0032212; GO:0044053; GO:0044297; GO:0050821; GO:0051082; GO:0051973; GO:0061077; GO:0090666; GO:0140662; GO:1901998; GO:1904851; GO:1904874; GO:2000109 26609 FUN_028653 83 47 35 69 6 NA NA NA NA NA NA NA 26610 FUN_028650 11 0 0 25 15 ptg000022l:2108570-2132810 Q9NBX4 2.59e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26611 FUN_028650 11 0 0 25 15 ptg000022l:2108570-2132810 Q9NBX4 2.59e-24 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26612 FUN_028656 5 53 6 21 22 NA NA NA NA NA NA NA 26613 FUN_028655 26 13 8 2 0 ptg000022l:2276932-2286390 Q96AY4 4.41e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26614 FUN_028655 26 13 8 2 0 ptg000022l:2276932-2286390 Q96AY4 1.42e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26615 FUN_028655 26 13 8 2 0 ptg000022l:2276932-2286390 Q96AY4 5.74e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26616 FUN_028655 26 13 8 2 0 ptg000022l:2276932-2286390 Q96AY4 2.04e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26617 FUN_026230 462 253 211 75 203 ptg000020l:6452813-6478430 P16157 1.68e-42 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26618 FUN_026230 462 253 211 75 203 ptg000020l:6452813-6478430 P16157 8.83e-41 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26619 FUN_026230 462 253 211 75 203 ptg000020l:6452813-6478430 P16157 5.29e-40 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26620 FUN_026230 462 253 211 75 203 ptg000020l:6452813-6478430 P16157 5.51e-27 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26621 FUN_026230 462 253 211 75 203 ptg000020l:6452813-6478430 P16157 2.92e-25 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 26622 FUN_023609 87 22 27 33 88 ptg000017l:9890309-9891611 Q80XJ3 2.63e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 26623 FUN_018034 328 25 21 25 351 NA NA NA NA NA NA NA 26624 FUN_028659 22 5 6 13 3 ptg000022l:2315800-2325885 Q96AY4 2.23e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26625 FUN_028659 22 5 6 13 3 ptg000022l:2315800-2325885 Q96AY4 7.63e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26626 FUN_028659 22 5 6 13 3 ptg000022l:2315800-2325885 Q96AY4 9.9e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26627 FUN_028659 22 5 6 13 3 ptg000022l:2315800-2325885 Q96AY4 1.02e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26628 FUN_028659 22 5 6 13 3 ptg000022l:2315800-2325885 Q96AY4 1.57e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26629 FUN_028658 0 0 0 7 0 NA NA NA NA NA NA NA 26630 FUN_026238 150 278 172 197 142 NA NA NA NA NA NA NA 26631 FUN_025764 564 5011 2358 2205 1021 NA NA NA NA NA NA NA 26632 FUN_025765 619 388 435 900 885 NA NA NA NA NA NA NA 26633 FUN_025766 907 877 488 767 869 ptg000020l:560770-564982 Q8BMK1 2.02e-22 tRNA N(3)-methylcytidine methyltransferase METTL2 (EC 2.1.1.-) (Methyltransferase-like protein 2) Mus musculus (Mouse) tRNA methylation [GO:0030488] GO:0005737; GO:0016427; GO:0030488; GO:0052735 26634 FUN_025766 907 877 488 767 869 ptg000020l:560770-564982 Q8BMK1 2.02e-22 tRNA N(3)-methylcytidine methyltransferase METTL2 (EC 2.1.1.-) (Methyltransferase-like protein 2) Mus musculus (Mouse) tRNA methylation [GO:0030488] GO:0005737; GO:0016427; GO:0030488; GO:0052735 26635 FUN_025766 907 877 488 767 869 ptg000020l:560770-564982 Q8BMK1 2.02e-22 tRNA N(3)-methylcytidine methyltransferase METTL2 (EC 2.1.1.-) (Methyltransferase-like protein 2) Mus musculus (Mouse) tRNA methylation [GO:0030488] GO:0005737; GO:0016427; GO:0030488; GO:0052735 26636 FUN_025767 5548 4502 2722 6473 4494 ptg000020l:569956-571000 O43623 4.66e-69 Zinc finger protein SNAI2 (Neural crest transcription factor Slug) (Protein snail homolog 2) Homo sapiens (Human) aortic valve morphogenesis [GO:0003180]; cartilage morphogenesis [GO:0060536]; cell migration involved in endocardial cushion formation [GO:0003273]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to ionizing radiation [GO:0071479]; desmosome disassembly [GO:0035921]; endothelial cell migration [GO:0043542]; epithelial to mesenchymal transition [GO:0001837]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; epithelium development [GO:0060429]; hematopoietic stem cell proliferation [GO:0071425]; myeloid cell apoptotic process [GO:0033028]; negative regulation of anoikis [GO:2000811]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cell adhesion involved in substrate-bound cell migration [GO:0006933]; negative regulation of cell adhesion mediated by integrin [GO:0033629]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043518]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of hematopoietic stem cell proliferation [GO:1902034]; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902230]; negative regulation of keratinocyte proliferation [GO:0010839]; negative regulation of myeloid cell apoptotic process [GO:0033033]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vitamin D biosynthetic process [GO:0010957]; negative regulation of vitamin D receptor signaling pathway [GO:0070563]; neural crest cell development [GO:0014032]; Notch signaling involved in heart development [GO:0061314]; Notch signaling pathway [GO:0007219]; osteoblast differentiation [GO:0001649]; pigmentation [GO:0043473]; positive regulation of cell migration [GO:0030335]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of histone acetylation [GO:0035066]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of branching involved in salivary gland morphogenesis [GO:0060693]; regulation of chemokine production [GO:0032642]; regulation of DNA-templated transcription [GO:0006355]; regulation of osteoblast differentiation [GO:0045667]; roof of mouth development [GO:0060021]; sensory perception of sound [GO:0007605]; white fat cell differentiation [GO:0050872] GO:0000122; GO:0000785; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001649; GO:0001837; GO:0003180; GO:0003198; GO:0003273; GO:0003682; GO:0005634; GO:0005654; GO:0005737; GO:0006355; GO:0006933; GO:0007219; GO:0007605; GO:0010839; GO:0010957; GO:0014032; GO:0030335; GO:0032331; GO:0032642; GO:0033028; GO:0033033; GO:0033629; GO:0035066; GO:0035921; GO:0043473; GO:0043518; GO:0043542; GO:0043565; GO:0045600; GO:0045667; GO:0046872; GO:0050872; GO:0060021; GO:0060429; GO:0060536; GO:0060693; GO:0061314; GO:0070563; GO:0070888; GO:0071364; GO:0071425; GO:0071479; GO:0090090; GO:1902034; GO:1902230; GO:1990837; GO:2000810; GO:2000811; GO:2001240 26637 FUN_025760 2458 1500 1175 2558 1837 ptg000020l:519606-526213 Q66JY2 3.54e-27 INO80 complex subunit D Mus musculus (Mouse) chromatin remodeling [GO:0006338]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of telomere maintenance in response to DNA damage [GO:1904507]; regulation of cell cycle [GO:0051726]; regulation of chromosome organization [GO:0033044]; regulation of DNA repair [GO:0006282]; regulation of DNA replication [GO:0006275]; regulation of DNA strand elongation [GO:0060382]; regulation of embryonic development [GO:0045995]; telomere maintenance [GO:0000723] GO:0000723; GO:0005634; GO:0006275; GO:0006281; GO:0006282; GO:0006310; GO:0006338; GO:0031011; GO:0033044; GO:0045739; GO:0045893; GO:0045995; GO:0051726; GO:0060382; GO:1904507 26638 FUN_025761 28 8 11 25 43 NA NA NA NA NA NA NA 26639 FUN_025762 2329 1306 1254 1032 1478 NA NA NA NA NA NA NA 26640 FUN_025763 3038 2557 2415 3183 3527 NA NA NA NA NA NA NA 26641 FUN_025768 1427 1906 2919 1929 1976 NA NA NA NA NA NA NA 26642 FUN_025769 828 214 249 560 467 NA NA NA NA NA NA NA 26643 FUN_027814 1848 1693 1701 3861 2859 NA NA NA NA NA NA NA 26644 FUN_027815 2317 1602 1191 2227 2553 NA NA NA NA NA NA NA 26645 FUN_041142 0 0 0 0 14 NA NA NA NA NA NA NA 26646 FUN_041141 90 0 156 31 134 NA NA NA NA NA NA NA 26647 FUN_041147 21 0 24 2 116 NA NA NA NA NA NA NA 26648 FUN_041144 1 1 0 0 9 NA NA NA NA NA NA NA 26649 FUN_041145 8 0 4 0 0 NA NA NA NA NA NA NA 26650 FUN_012738 18 71 16 243 79 NA NA NA NA NA NA NA 26651 FUN_011868 3448 3571 1824 2636 1474 NA NA NA NA NA NA NA 26652 FUN_011869 498 525 413 492 453 NA NA NA NA NA NA NA 26653 FUN_011864 846 456 506 779 227 NA NA NA NA NA NA NA 26654 FUN_011865 3091 2190 1330 2238 1817 NA NA NA NA NA NA NA 26655 FUN_011866 7568 7488 4311 4933 2283 NA NA NA NA NA NA NA 26656 FUN_011867 1475 1119 1121 1160 1153 NA NA NA NA NA NA NA 26657 FUN_011860 9 7 2 10 10 NA NA NA NA NA NA NA 26658 FUN_011861 1244 617 606 1001 815 NA NA NA NA NA NA NA 26659 FUN_011862 166 228 115 87 174 NA NA NA NA NA NA NA 26660 FUN_011863 22477 24821 15365 19863 11410 NA NA NA NA NA NA NA 26661 FUN_005146 241 28 29 2881 6872 NA NA NA NA NA NA NA 26662 FUN_008028 5433 8198 3397 5227 3005 NA NA NA NA NA NA NA 26663 FUN_008029 2188 1032 711 1882 1024 NA NA NA NA NA NA NA 26664 FUN_008023 4481 4062 2693 4711 5677 NA NA NA NA NA NA NA 26665 FUN_008020 6807 5161 3705 5822 4566 ptg000002l:7271439-7303918 Q03141 2.18e-42 MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of hippo signaling [GO:0035331]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein binding [GO:0032092]; protein phosphorylation [GO:0006468] GO:0000226; GO:0004674; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0018105; GO:0030425; GO:0032092; GO:0035331; GO:0035556; GO:0036289; GO:0050321; GO:0106310 26666 FUN_008020 6807 5161 3705 5822 4566 ptg000002l:7271439-7303918 Q03141 1.36e-39 MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (ELKL motif kinase 2) (EMK-2) (MPK-10) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; microtubule cytoskeleton organization [GO:0000226]; negative regulation of hippo signaling [GO:0035331]; peptidyl-serine autophosphorylation [GO:0036289]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of protein binding [GO:0032092]; protein phosphorylation [GO:0006468] GO:0000226; GO:0004674; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0018105; GO:0030425; GO:0032092; GO:0035331; GO:0035556; GO:0036289; GO:0050321; GO:0106310 26667 FUN_008021 945 328 515 980 1154 NA NA NA NA NA NA NA 26668 FUN_008026 272 289 222 345 343 ptg000002l:7336238-7341508 A0MGZ5 4.37e-109 Heparan-sulfate 6-O-sulfotransferase 1-B (HS 6-OST-1B) (EC 2.8.2.-) Danio rerio (Zebrafish) (Brachydanio rerio) heparan sulfate proteoglycan biosynthetic process, enzymatic modification [GO:0015015] GO:0015015; GO:0016020; GO:0017095 26669 FUN_008027 1955 1279 701 1913 689 NA NA NA NA NA NA NA 26670 FUN_008024 839 641 368 634 632 NA NA NA NA NA NA NA 26671 FUN_008025 5476 5333 3872 5656 5823 NA NA NA NA NA NA NA 26672 FUN_024495 0 8 1 0 0 NA NA NA NA NA NA NA 26673 FUN_024494 22 15 12 12 79 NA NA NA NA NA NA NA 26674 FUN_044019 28 5 23 2 57 NA NA NA NA NA NA NA 26675 FUN_024493 63 5 10 76 31 NA NA NA NA NA NA NA 26676 FUN_024492 6 0 0 0 17 NA NA NA NA NA NA NA 26677 FUN_044012 1 0 1 0 6 NA NA NA NA NA NA NA 26678 FUN_044017 13 4 8 11 15 NA NA NA NA NA NA NA 26679 FUN_044016 239 21 38 261 332 ptg000070l:80889-82170 Q96AY4 1.16e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26680 FUN_022269 70 47 46 8 38 NA NA NA NA NA NA NA 26681 FUN_022260 21672 20347 10104 17159 14442 ptg000016l:6978767-6980716 P61210 2.25e-51 ADP-ribosylation factor 1 (EC 3.6.5.2) (lARF1) Locusta migratoria (Migratory locust) establishment of localization in cell [GO:0051649]; protein transport [GO:0015031]; system development [GO:0048731]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0015031; GO:0016192; GO:0048731; GO:0051649 26682 FUN_022260 21672 20347 10104 17159 14442 ptg000016l:6978767-6980716 P61210 2.25e-51 ADP-ribosylation factor 1 (EC 3.6.5.2) (lARF1) Locusta migratoria (Migratory locust) establishment of localization in cell [GO:0051649]; protein transport [GO:0015031]; system development [GO:0048731]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0015031; GO:0016192; GO:0048731; GO:0051649 26683 FUN_022260 21672 20347 10104 17159 14442 ptg000016l:6978767-6980716 P61210 6.67e-26 ADP-ribosylation factor 1 (EC 3.6.5.2) (lARF1) Locusta migratoria (Migratory locust) establishment of localization in cell [GO:0051649]; protein transport [GO:0015031]; system development [GO:0048731]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0015031; GO:0016192; GO:0048731; GO:0051649 26684 FUN_022261 1081 734 519 1246 726 NA NA NA NA NA NA NA 26685 FUN_022262 469 957 408 368 115 NA NA NA NA NA NA NA 26686 FUN_022263 1043 1928 1191 1005 475 NA NA NA NA NA NA NA 26687 FUN_022264 3087 2799 1793 2445 2439 NA NA NA NA NA NA NA 26688 FUN_022265 879 554 634 772 1018 NA NA NA NA NA NA NA 26689 FUN_022266 556 1046 237 637 386 ptg000016l:7019887-7020796 Q28199 2.14e-50 Cyclin-dependent kinase 5 activator 1 (CDK5 activator 1) (Cyclin-dependent kinase 5 regulatory subunit 1) (TPKII regulatory subunit) [Cleaved into: Cyclin-dependent kinase 5 activator 1, p35 (p35); Cyclin-dependent kinase 5 activator 1, p25 (p25) (Tau protein kinase II 23 kDa subunit) (p23)] Bos taurus (Bovine) axon guidance [GO:0007411]; axonal fasciculation [GO:0007413]; brain development [GO:0007420]; cerebellum development [GO:0021549]; embryo development ending in birth or egg hatching [GO:0009792]; ephrin receptor signaling pathway [GO:0048013]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G1 to G0 transition involved in cell differentiation [GO:0070315]; hippocampus development [GO:0021766]; ionotropic glutamate receptor signaling pathway [GO:0035235]; layer formation in cerebral cortex [GO:0021819]; negative regulation of DNA-templated transcription [GO:0045892]; neuron cell-cell adhesion [GO:0007158]; neuron differentiation [GO:0030182]; neuron migration [GO:0001764]; neuron projection development [GO:0031175]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein targeting to membrane [GO:0090314]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of dendritic spine morphogenesis [GO:0061001]; rhythmic process [GO:0048511]; serine phosphorylation of STAT protein [GO:0042501]; superior olivary nucleus maturation [GO:0021722] GO:0000307; GO:0001764; GO:0002020; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005886; GO:0007158; GO:0007213; GO:0007411; GO:0007413; GO:0007420; GO:0009792; GO:0014069; GO:0016020; GO:0016301; GO:0016533; GO:0018107; GO:0019901; GO:0021549; GO:0021722; GO:0021766; GO:0021819; GO:0030182; GO:0030424; GO:0030425; GO:0030426; GO:0031116; GO:0031175; GO:0031594; GO:0032956; GO:0035235; GO:0035255; GO:0042501; GO:0043005; GO:0043014; GO:0043025; GO:0043197; GO:0043204; GO:0043292; GO:0043525; GO:0043539; GO:0045296; GO:0045860; GO:0045892; GO:0048013; GO:0048471; GO:0048487; GO:0048511; GO:0051015; GO:0061001; GO:0061575; GO:0070315; GO:0090314 26690 FUN_022267 60 51 26 66 110 ptg000016l:7027274-7034505 Q63357 1.01e-33 Unconventional myosin-Id (Myosin heavy chain myr 4) Rattus norvegicus (Rat) actin filament organization [GO:0007015]; cellular localization [GO:0051641]; forebrain development [GO:0030900]; protein transport [GO:0015031]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0005516; GO:0005524; GO:0005737; GO:0005769; GO:0005790; GO:0005886; GO:0005902; GO:0005903; GO:0005938; GO:0007015; GO:0015031; GO:0015629; GO:0016323; GO:0016459; GO:0019904; GO:0030050; GO:0030424; GO:0030673; GO:0030900; GO:0031410; GO:0031982; GO:0043005; GO:0043025; GO:0043204; GO:0043209; GO:0044853; GO:0048306; GO:0051015; GO:0051641; GO:0097440 26691 FUN_024149 491 450 360 610 234 NA NA NA NA NA NA NA 26692 FUN_024148 108 153 43 153 44 NA NA NA NA NA NA NA 26693 FUN_024147 1 126 47 135 12 NA NA NA NA NA NA NA 26694 FUN_024146 21 124 108 56 20 NA NA NA NA NA NA NA 26695 FUN_024145 609 803 204 421 288 NA NA NA NA NA NA NA 26696 FUN_024144 2055 2477 268 1460 507 NA NA NA NA NA NA NA 26697 FUN_024143 156 100 134 83 70 NA NA NA NA NA NA NA 26698 FUN_024142 198 153 219 278 130 NA NA NA NA NA NA NA 26699 FUN_024141 193 78 73 230 185 ptg000018l:2652803-2653958 P58308 8.96e-26 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Mus musculus (Mouse) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0017046; GO:0022410; GO:0040011; GO:0051480 26700 FUN_024140 55 27 21 32 41 NA NA NA NA NA NA NA 26701 FUN_012404 0 0 0 0 24 NA NA NA NA NA NA NA 26702 FUN_036868 297 221 197 273 237 NA NA NA NA NA NA NA 26703 FUN_023088 21 79 9 4 77 NA NA NA NA NA NA NA 26704 FUN_036862 0 213 0 0 0 NA NA NA NA NA NA NA 26705 FUN_041510 1200 769 618 987 604 ptg000035l:4515169-4518487 Q9EQN9 3.01e-92 Thiamine transporter 1 (ThTr-1) (Solute carrier family 19 member 2) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283]; thiamine transmembrane transport [GO:0071934]; thiamine transport [GO:0015888]; transmembrane transport [GO:0055085] GO:0005886; GO:0007283; GO:0015234; GO:0015888; GO:0030154; GO:0055085; GO:0071934 26706 FUN_026988 1458 1521 1472 3212 2084 NA NA NA NA NA NA NA 26707 FUN_039792 497 543 237 231 235 NA NA NA NA NA NA NA 26708 FUN_039797 90 51 32 0 17 NA NA NA NA NA NA NA 26709 FUN_039798 208 430 129 441 392 NA NA NA NA NA NA NA 26710 FUN_039799 3 1 22 7 0 NA NA NA NA NA NA NA 26711 FUN_041514 3335 2020 1643 3214 2247 NA NA NA NA NA NA NA 26712 FUN_037420 313 31 472 903 616 NA NA NA NA NA NA NA 26713 FUN_037421 1185 1072 986 1302 1077 NA NA NA NA NA NA NA 26714 FUN_037422 4353 744 594 3632 985 NA NA NA NA NA NA NA 26715 FUN_037423 23 61 25 9 14 NA NA NA NA NA NA NA 26716 FUN_037424 958 484 367 492 428 NA NA NA NA NA NA NA 26717 FUN_037425 2217 2529 1137 2533 2433 NA NA NA NA NA NA NA 26718 FUN_037426 482 379 226 233 81 ptg000026l:10212946-10214773 Q92179 7.52e-31 Carbohydrate sulfotransferase 3 (EC 2.8.2.17) (EC 2.8.2.21) (Chondroitin 6-O-sulfotransferase 1) (C6ST-1) (Chondroitin 6-sulfotransferase) (C6ST) Gallus gallus (Chicken) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate biosynthetic process [GO:0030206]; N-acetylglucosamine metabolic process [GO:0006044]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006790; GO:0008459; GO:0030206 26719 FUN_037427 0 0 59 110 44 NA NA NA NA NA NA NA 26720 FUN_037428 116 40 106 519 128 NA NA NA NA NA NA NA 26721 FUN_005700 2162 1113 880 1041 937 NA NA NA NA NA NA NA 26722 FUN_005702 0 6 18 11 13 NA NA NA NA NA NA NA 26723 FUN_005703 0 0 0 0 7 NA NA NA NA NA NA NA 26724 FUN_034021 752 833 467 732 746 ptg000024l:3800368-3804053 Q5ZHN9 4.47e-35 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1) Gallus gallus (Chicken) cardiolipin biosynthetic process [GO:0032049] GO:0005524; GO:0005739; GO:0008444; GO:0032049 26725 FUN_034021 752 833 467 732 746 ptg000024l:3800368-3804053 Q5ZHN9 3.67e-28 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1) Gallus gallus (Chicken) cardiolipin biosynthetic process [GO:0032049] GO:0005524; GO:0005739; GO:0008444; GO:0032049 26726 FUN_034021 752 833 467 732 746 ptg000024l:3800368-3804053 Q5ZHN9 3.95e-22 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1) Gallus gallus (Chicken) cardiolipin biosynthetic process [GO:0032049] GO:0005524; GO:0005739; GO:0008444; GO:0032049 26727 FUN_005705 324 183 221 213 169 NA NA NA NA NA NA NA 26728 FUN_005708 0 0 0 0 32 NA NA NA NA NA NA NA 26729 FUN_001410 181 118 36 181 94 NA NA NA NA NA NA NA 26730 FUN_001411 899 871 462 674 526 NA NA NA NA NA NA NA 26731 FUN_001412 2028 3791 2716 2292 1506 NA NA NA NA NA NA NA 26732 FUN_028676 14 2 0 1 13 NA NA NA NA NA NA NA 26733 FUN_001414 178 121 162 151 157 NA NA NA NA NA NA NA 26734 FUN_001415 5671 5583 5387 3441 2265 NA NA NA NA NA NA NA 26735 FUN_001416 2260 1814 1378 2380 2446 NA NA NA NA NA NA NA 26736 FUN_001417 1476 1209 1200 1970 1842 ntLink_6:12124889-12139247 Q9NZN8 7.92e-26 CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2) Homo sapiens (Human) negative regulation of intracellular estrogen receptor signaling pathway [GO:0033147]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; positive regulation of cytoplasmic mRNA processing body assembly [GO:0010606]; regulation of stem cell population maintenance [GO:2000036]; regulation of transcription by RNA polymerase II [GO:0006357]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; RNA-mediated gene silencing [GO:0031047]; trophectodermal cell differentiation [GO:0001829] GO:0000122; GO:0000289; GO:0000932; GO:0001222; GO:0001829; GO:0003712; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006357; GO:0010606; GO:0016020; GO:0030014; GO:0030015; GO:0031047; GO:0033147; GO:0090503; GO:2000036 26737 FUN_001418 5418 3354 1809 3847 3250 NA NA NA NA NA NA NA 26738 FUN_001419 30 0 51 17 70 ntLink_6:12173714-12196418 Q95SX7 1.85e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26739 FUN_026178 40 59 42 0 87 NA NA NA NA NA NA NA 26740 FUN_026179 3462 2023 1779 3095 2473 NA NA NA NA NA NA NA 26741 FUN_026174 1129 1012 469 585 350 NA NA NA NA NA NA NA 26742 FUN_026177 6050 4623 3533 6162 5796 NA NA NA NA NA NA NA 26743 FUN_026170 59 0 0 0 0 NA NA NA NA NA NA NA 26744 FUN_026171 239 48 54 36 88 NA NA NA NA NA NA NA 26745 FUN_026172 361 254 267 400 135 NA NA NA NA NA NA NA 26746 FUN_026173 4214 4325 4966 3426 984 NA NA NA NA NA NA NA 26747 FUN_004071 140 127 79 138 156 NA NA NA NA NA NA NA 26748 FUN_004073 762 267 270 523 303 ntLink_8:18913586-18914588 P58307 2.73e-29 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Mus musculus (Mouse) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 26749 FUN_004072 139 116 276 224 169 NA NA NA NA NA NA NA 26750 FUN_004075 0 48 52 0 227 NA NA NA NA NA NA NA 26751 FUN_004074 2 0 2 8 71 NA NA NA NA NA NA NA 26752 FUN_004077 9 0 8 0 5 NA NA NA NA NA NA NA 26753 FUN_028533 0 0 0 0 8 NA NA NA NA NA NA NA 26754 FUN_004079 1015 1069 1068 1475 1754 NA NA NA NA NA NA NA 26755 FUN_004078 1123 1149 690 847 889 NA NA NA NA NA NA NA 26756 FUN_002406 1821 2504 1491 756 1040 NA NA NA NA NA NA NA 26757 FUN_011713 62 30 17 54 55 NA NA NA NA NA NA NA 26758 FUN_010947 2291 706 1173 816 1092 NA NA NA NA NA NA NA 26759 FUN_011710 6666 5989 3910 6074 5167 ptg000008l:434279-452631 Q5RB36 3.34e-23 Cullin-5 (CUL-5) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0006511; GO:0016567; GO:0031461; GO:0031625; GO:0090734 26760 FUN_010948 4374 3853 1949 4961 3098 ptg000007l:4681346-4684489 P83852 9.65e-46 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 26761 FUN_010948 4374 3853 1949 4961 3098 ptg000007l:4681346-4684489 P83852 2.03e-22 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 26762 FUN_002405 29 0 55 0 10 ntLink_8:1153236-1157693 O57525 2.86e-80 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Rana dybowskii (Dybovsky's frog) (Korean brown frog) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 26763 FUN_031969 1207 864 614 830 700 NA NA NA NA NA NA NA 26764 FUN_031968 460 303 211 207 438 NA NA NA NA NA NA NA 26765 FUN_031967 49 24 41 47 5 ptg000023l:27226484-27228540 Q95M17 3.7e-102 Acidic mammalian chitinase (AMCase) (EC 3.2.1.14) (Chitin-binding protein b04) (CBPb04) Bos taurus (Bovine) apoptotic process [GO:0006915]; chitin catabolic process [GO:0006032]; immune system process [GO:0002376]; polysaccharide catabolic process [GO:0000272]; positive regulation of chemokine production [GO:0032722]; production of molecular mediator involved in inflammatory response [GO:0002532] GO:0000272; GO:0002376; GO:0002532; GO:0004568; GO:0005615; GO:0005737; GO:0006032; GO:0006915; GO:0008061; GO:0032722 26766 FUN_031966 51 7 27 47 65 NA NA NA NA NA NA NA 26767 FUN_031965 212 71 220 330 137 NA NA NA NA NA NA NA 26768 FUN_031964 0 0 0 10 0 NA NA NA NA NA NA NA 26769 FUN_031963 12 0 3 0 15 ptg000023l:27169858-27171226 Q61184 2.32e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 26770 FUN_031962 17 0 3 0 12 ptg000023l:27165400-27166768 Q61184 2.32e-24 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 26771 FUN_031961 8 0 0 0 8 ptg000023l:27158411-27162310 Q61184 2.02e-23 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 26772 FUN_011717 51 21 53 18 9 NA NA NA NA NA NA NA 26773 FUN_034300 7545 5101 3322 7526 5373 NA NA NA NA NA NA NA 26774 FUN_034301 2463 1337 1331 1109 816 NA NA NA NA NA NA NA 26775 FUN_034302 421 277 252 291 361 NA NA NA NA NA NA NA 26776 FUN_034303 730 406 464 681 634 NA NA NA NA NA NA NA 26777 FUN_034304 911 487 651 788 472 NA NA NA NA NA NA NA 26778 FUN_034305 895 601 525 1020 734 NA NA NA NA NA NA NA 26779 FUN_034306 377 197 292 588 293 NA NA NA NA NA NA NA 26780 FUN_034308 0 0 27 0 33 NA NA NA NA NA NA NA 26781 FUN_002401 38 0 18 102 6 NA NA NA NA NA NA NA 26782 FUN_028534 0 0 24 0 20 NA NA NA NA NA NA NA 26783 FUN_041420 2 4 12 0 12 NA NA NA NA NA NA NA 26784 FUN_028535 0 0 13 0 23 NA NA NA NA NA NA NA 26785 FUN_000216 4281 2571 1718 2117 1260 NA NA NA NA NA NA NA 26786 FUN_007030 95 42 19 0 78 NA NA NA NA NA NA NA 26787 FUN_000211 60 0 55 40 296 NA NA NA NA NA NA NA 26788 FUN_007032 28 0 8 0 39 NA NA NA NA NA NA NA 26789 FUN_007034 0 0 0 0 6 NA NA NA NA NA NA NA 26790 FUN_007036 17 0 9 0 63 NA NA NA NA NA NA NA 26791 FUN_041424 2 0 0 0 10 NA NA NA NA NA NA NA 26792 FUN_005888 0 0 2 0 17 NA NA NA NA NA NA NA 26793 FUN_005887 83 82 57 76 334 NA NA NA NA NA NA NA 26794 FUN_005885 5 0 0 0 28 NA NA NA NA NA NA NA 26795 FUN_005884 556 377 400 488 297 NA NA NA NA NA NA NA 26796 FUN_005883 8117 6674 4998 6024 4890 NA NA NA NA NA NA NA 26797 FUN_005882 2836 2086 1220 1509 698 NA NA NA NA NA NA NA 26798 FUN_005881 814 778 359 614 482 ptg000001l:5190411-5191233 Q58DT4 9.15e-71 Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2) Bos taurus (Bovine) cellular response to oxidative stress [GO:0034599]; L-proline biosynthetic process [GO:0055129]; proline biosynthetic process [GO:0006561] GO:0004735; GO:0005739; GO:0006561; GO:0034599; GO:0055129 26799 FUN_005880 8 1 8 8 2 NA NA NA NA NA NA NA 26800 FUN_019005 0 0 0 0 12 NA NA NA NA NA NA NA 26801 FUN_019002 0 0 0 0 12 NA NA NA NA NA NA NA 26802 FUN_019009 0 0 11 57 2 NA NA NA NA NA NA NA 26803 FUN_034876 143 167 296 246 368 NA NA NA NA NA NA NA 26804 FUN_034877 32 0 23 39 122 NA NA NA NA NA NA NA 26805 FUN_034874 4218 4550 2822 5447 4277 NA NA NA NA NA NA NA 26806 FUN_034875 1539 1284 1264 1650 1319 NA NA NA NA NA NA NA 26807 FUN_034872 121 114 103 225 54 ptg000025l:1070571-1071703 Q9XTR8 6.35e-36 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 26808 FUN_034873 1782 931 800 1545 1090 NA NA NA NA NA NA NA 26809 FUN_034870 884 357 751 1511 1262 NA NA NA NA NA NA NA 26810 FUN_034871 8622 6379 3585 6596 5908 NA NA NA NA NA NA NA 26811 FUN_034878 3419 1956 1836 3456 2625 NA NA NA NA NA NA NA 26812 FUN_036744 123 95 51 133 241 NA NA NA NA NA NA NA 26813 FUN_030375 7 1 10 0 27 ptg000023l:10726030-10726793 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26814 FUN_030377 4 0 6 0 23 ptg000023l:10730082-10730845 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26815 FUN_030371 7 0 9 0 27 ptg000023l:10717926-10718689 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26816 FUN_030373 5 0 8 1 25 ptg000023l:10721978-10722741 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26817 FUN_030379 9 1 5 0 26 ptg000023l:10734134-10734897 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 26818 FUN_001694 11 0 0 1 14 NA NA NA NA NA NA NA 26819 FUN_036749 314 443 284 758 726 NA NA NA NA NA NA NA 26820 FUN_039844 43 22 11 11 29 NA NA NA NA NA NA NA 26821 FUN_033829 95 13 38 0 0 ptg000024l:1720133-1723243 Q6L8S8 3.34e-26 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 26822 FUN_006341 35 21 32 37 34 NA NA NA NA NA NA NA 26823 FUN_006343 0 0 0 0 139 NA NA NA NA NA NA NA 26824 FUN_006342 30 0 117 71 64 NA NA NA NA NA NA NA 26825 FUN_042147 25 11 24 0 3 NA NA NA NA NA NA NA 26826 FUN_022743 31 4 10 6 17 ptg000016l:12707049-12707935 P25291 7.52e-28 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 26827 FUN_022742 50 14 32 16 19 ptg000016l:12705934-12706817 P25291 1.23e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 26828 FUN_009144 12 0 58 9 24 NA NA NA NA NA NA NA 26829 FUN_022740 45 20 30 32 24 ptg000016l:12703696-12704582 P25291 1.44e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 26830 FUN_009142 0 14 37 0 38 NA NA NA NA NA NA NA 26831 FUN_022746 37 7 11 7 17 ptg000016l:12711516-12712402 P25291 5.28e-28 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 26832 FUN_022745 92 21 45 34 34 ptg000016l:12709286-12711284 P25291 5.72e-26 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 26833 FUN_022745 92 21 45 34 34 ptg000016l:12709286-12711284 P25291 9.48e-26 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 26834 FUN_018962 0 0 0 24 20 NA NA NA NA NA NA NA 26835 FUN_009141 96 32 58 160 43 NA NA NA NA NA NA NA 26836 FUN_039749 49 1644 2068 1102 1255 NA NA NA NA NA NA NA 26837 FUN_018963 4 11 0 0 0 NA NA NA NA NA NA NA 26838 FUN_039748 0 0 0 0 26 NA NA NA NA NA NA NA 26839 FUN_004826 113 140 77 321 173 NA NA NA NA NA NA NA 26840 FUN_004827 401 275 335 591 374 NA NA NA NA NA NA NA 26841 FUN_004824 35 28 0 122 29 NA NA NA NA NA NA NA 26842 FUN_004822 95 53 40 150 66 NA NA NA NA NA NA NA 26843 FUN_004823 94 50 71 190 69 NA NA NA NA NA NA NA 26844 FUN_004820 906 416 401 1096 844 NA NA NA NA NA NA NA 26845 FUN_004821 993 499 585 5318 2651 NA NA NA NA NA NA NA 26846 FUN_036430 7 0 0 19 4 NA NA NA NA NA NA NA 26847 FUN_036431 11 4 12 0 0 NA NA NA NA NA NA NA 26848 FUN_036433 31 0 0 0 0 NA NA NA NA NA NA NA 26849 FUN_003839 2198 1906 1038 1904 1351 ntLink_8:15911894-15918875 Q8TF64 4.41e-47 PDZ domain-containing protein GIPC3 Homo sapiens (Human) NA NA 26850 FUN_004828 116 62 194 164 168 NA NA NA NA NA NA NA 26851 FUN_040787 0 0 12 0 19 ptg000031l:12696960-12698331 Q09575 4.49e-50 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 26852 FUN_040786 0 0 20 0 20 NA NA NA NA NA NA NA 26853 FUN_040785 13 66 192 205 93 NA NA NA NA NA NA NA 26854 FUN_040784 2877 2047 1159 2986 3766 ptg000031l:12653616-12663860 O65201 8.83e-21 Acyl-coenzyme A oxidase 2, peroxisomal (AOX 2) (EC 1.3.3.6) (Long-chain acyl-CoA oxidase) (AtCX2) Arabidopsis thaliana (Mouse-ear cress) fatty acid beta-oxidation [GO:0006635]; fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088]; long-chain fatty acid metabolic process [GO:0001676] GO:0001676; GO:0003997; GO:0005504; GO:0005777; GO:0006635; GO:0033540; GO:0050660; GO:0055088; GO:0071949 26855 FUN_040783 14675 6863 5608 12573 9652 ptg000031l:12638941-12648251 P33198 1.44e-22 Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) Sus scrofa (Pig) 2-oxoglutarate metabolic process [GO:0006103]; glyoxylate cycle [GO:0006097]; isocitrate metabolic process [GO:0006102]; NADP metabolic process [GO:0006739]; tricarboxylic acid cycle [GO:0006099] GO:0000287; GO:0004450; GO:0005739; GO:0006097; GO:0006099; GO:0006102; GO:0006103; GO:0006739; GO:0051287 26856 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 6.72e-71 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26857 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 1.1e-46 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26858 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 1.17e-36 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26859 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 1.18e-33 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26860 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 1.18e-33 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26861 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 1.1e-31 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26862 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 7.08e-31 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26863 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 4.12e-29 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26864 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 4.12e-29 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26865 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 2.64e-22 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26866 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 7.05e-22 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26867 FUN_040782 5503 3652 3033 5922 5797 ptg000031l:12544262-12635861 Q15751 7.05e-22 Probable E3 ubiquitin-protein ligase HERC1 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 1) (HECT-type E3 ubiquitin transferase HERC1) (p532) (p619) Homo sapiens (Human) autophagy [GO:0006914]; cerebellar Purkinje cell differentiation [GO:0021702]; corpus callosum development [GO:0022038]; negative regulation of autophagy [GO:0010507]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175] GO:0004842; GO:0005085; GO:0005737; GO:0005794; GO:0005829; GO:0006914; GO:0010507; GO:0016020; GO:0021702; GO:0022038; GO:0031175; GO:0050885 26868 FUN_037741 3985 1944 1328 2387 1861 NA NA NA NA NA NA NA 26869 FUN_037740 992 1021 421 661 390 NA NA NA NA NA NA NA 26870 FUN_037743 852 1189 982 1647 1759 NA NA NA NA NA NA NA 26871 FUN_037742 19 48 39 112 202 NA NA NA NA NA NA NA 26872 FUN_037745 458 372 174 348 530 NA NA NA NA NA NA NA 26873 FUN_037744 4927 2717 2495 4219 3723 ptg000026l:13037611-13055793 Q9DDT5 2.82e-29 Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Protein foggy) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system neuron development [GO:0021954]; hemopoiesis [GO:0030097]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; neuron migration [GO:0001764]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of hematopoietic stem cell differentiation [GO:1902038]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0001764; GO:0003677; GO:0003729; GO:0005634; GO:0006357; GO:0006368; GO:0021954; GO:0030097; GO:0032044; GO:0032968; GO:0034244; GO:0040037; GO:0046427; GO:0060335; GO:0140673; GO:1901534; GO:1902038 26874 FUN_037744 4927 2717 2495 4219 3723 ptg000026l:13037611-13055793 Q9DDT5 2.82e-29 Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Protein foggy) Danio rerio (Zebrafish) (Brachydanio rerio) central nervous system neuron development [GO:0021954]; hemopoiesis [GO:0030097]; negative regulation of fibroblast growth factor receptor signaling pathway [GO:0040037]; negative regulation of transcription elongation by RNA polymerase II [GO:0034244]; neuron migration [GO:0001764]; positive regulation of hematopoietic progenitor cell differentiation [GO:1901534]; positive regulation of hematopoietic stem cell differentiation [GO:1902038]; positive regulation of receptor signaling pathway via JAK-STAT [GO:0046427]; positive regulation of transcription elongation by RNA polymerase II [GO:0032968]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of transcription by RNA polymerase II [GO:0006357]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription elongation-coupled chromatin remodeling [GO:0140673] GO:0001764; GO:0003677; GO:0003729; GO:0005634; GO:0006357; GO:0006368; GO:0021954; GO:0030097; GO:0032044; GO:0032968; GO:0034244; GO:0040037; GO:0046427; GO:0060335; GO:0140673; GO:1901534; GO:1902038 26875 FUN_037747 652 635 633 1078 1146 NA NA NA NA NA NA NA 26876 FUN_037746 5194 2790 1823 2953 2382 ptg000026l:13070961-13084394 Q17162 1.7e-40 Vinculin Brugia malayi (Filarial nematode worm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0007155; GO:0051015 26877 FUN_037746 5194 2790 1823 2953 2382 ptg000026l:13070961-13084394 Q17162 1.7e-40 Vinculin Brugia malayi (Filarial nematode worm) cell adhesion [GO:0007155] GO:0005737; GO:0005856; GO:0005886; GO:0005912; GO:0007155; GO:0051015 26878 FUN_007083 10 13 11 0 57 NA NA NA NA NA NA NA 26879 FUN_007082 26 39 44 40 23 NA NA NA NA NA NA NA 26880 FUN_000929 812 488 231 758 615 NA NA NA NA NA NA NA 26881 FUN_000928 2290 2278 1391 1444 1858 NA NA NA NA NA NA NA 26882 FUN_006862 2270 1434 503 1300 969 ptg000001l:17520828-17524862 P13686 4.83e-22 Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase) Homo sapiens (Human) bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; dephosphorylation [GO:0016311]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; nitric oxide biosynthetic process [GO:0006809]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; superoxide anion generation [GO:0042554] GO:0003993; GO:0005764; GO:0005829; GO:0006809; GO:0008198; GO:0008199; GO:0010936; GO:0016020; GO:0016311; GO:0032496; GO:0032691; GO:0032695; GO:0032720; GO:0032929; GO:0034097; GO:0042554; GO:0045019; GO:0045453; GO:0050728; GO:0050830; GO:0060349 26883 FUN_006862 2270 1434 503 1300 969 ptg000001l:17520828-17524862 P13686 5.67e-21 Tartrate-resistant acid phosphatase type 5 (TR-AP) (EC 3.1.3.2) (Tartrate-resistant acid ATPase) (TrATPase) (Type 5 acid phosphatase) Homo sapiens (Human) bone morphogenesis [GO:0060349]; bone resorption [GO:0045453]; defense response to Gram-positive bacterium [GO:0050830]; dephosphorylation [GO:0016311]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; negative regulation of superoxide anion generation [GO:0032929]; negative regulation of tumor necrosis factor production [GO:0032720]; nitric oxide biosynthetic process [GO:0006809]; response to cytokine [GO:0034097]; response to lipopolysaccharide [GO:0032496]; superoxide anion generation [GO:0042554] GO:0003993; GO:0005764; GO:0005829; GO:0006809; GO:0008198; GO:0008199; GO:0010936; GO:0016020; GO:0016311; GO:0032496; GO:0032691; GO:0032695; GO:0032720; GO:0032929; GO:0034097; GO:0042554; GO:0045019; GO:0045453; GO:0050728; GO:0050830; GO:0060349 26884 FUN_000923 0 0 25 4 0 NA NA NA NA NA NA NA 26885 FUN_043189 0 30 6 28 5 NA NA NA NA NA NA NA 26886 FUN_005061 3697 6523 2357 4725 2198 NA NA NA NA NA NA NA 26887 FUN_005060 8752 6145 3147 11400 9075 NA NA NA NA NA NA NA 26888 FUN_005063 1785 1344 1023 2062 2520 NA NA NA NA NA NA NA 26889 FUN_005062 1963 1237 1157 1620 1600 NA NA NA NA NA NA NA 26890 FUN_005065 356 335 281 101 267 NA NA NA NA NA NA NA 26891 FUN_005064 0 0 21 0 28 NA NA NA NA NA NA NA 26892 FUN_005067 0 12 0 0 13 NA NA NA NA NA NA NA 26893 FUN_005066 4185 4844 1791 56 2053 NA NA NA NA NA NA NA 26894 FUN_001381 18 0 40 0 233 NA NA NA NA NA NA NA 26895 FUN_002879 22 0 22 0 157 NA NA NA NA NA NA NA 26896 FUN_002878 82 10 78 50 122 NA NA NA NA NA NA NA 26897 FUN_002876 7 17 0 22 3 NA NA NA NA NA NA NA 26898 FUN_002872 0 0 0 0 10 NA NA NA NA NA NA NA 26899 FUN_002871 380 229 172 379 305 NA NA NA NA NA NA NA 26900 FUN_031246 0 0 0 18 22 ptg000023l:18526916-18530645 Q94515 1.85e-109 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 26901 FUN_000581 1 1 10 6 8 NA NA NA NA NA NA NA 26902 FUN_000580 11837 8595 8324 12199 7959 NA NA NA NA NA NA NA 26903 FUN_000583 223 54 88 96 27 NA NA NA NA NA NA NA 26904 FUN_041559 118 188 87 106 63 NA NA NA NA NA NA NA 26905 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 2.82e-55 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26906 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 2.82e-55 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26907 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 2.82e-55 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26908 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 2.82e-55 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26909 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26910 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26911 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26912 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26913 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26914 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26915 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26916 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26917 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26918 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26919 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26920 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26921 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26922 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26923 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26924 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26925 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26926 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26927 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26928 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26929 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26930 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26931 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.18e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26932 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.56e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26933 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 3.26e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26934 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26935 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26936 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26937 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26938 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26939 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26940 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 4.95e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26941 FUN_000587 0 8 1 1 3 ntLink_6:4729428-4738824 Q03650 1.66e-37 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 26942 FUN_000586 298 414 145 764 433 NA NA NA NA NA NA NA 26943 FUN_000589 1994 1197 998 1484 780 NA NA NA NA NA NA NA 26944 FUN_041557 2929 1652 1460 3110 2445 ptg000035l:5136478-5171518 Q14669 3.79e-36 E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779]; regulation of embryonic development [GO:0045995]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006511; GO:0006974; GO:0016607; GO:0043161; GO:0045995; GO:0046966; GO:0061630; GO:0140861; GO:1901315; GO:2000779; GO:2000780 26945 FUN_041557 2929 1652 1460 3110 2445 ptg000035l:5136478-5171518 Q14669 2.42e-23 E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA repair-dependent chromatin remodeling [GO:0140861]; negative regulation of double-strand break repair [GO:2000780]; negative regulation of histone H2A K63-linked ubiquitination [GO:1901315]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; regulation of double-strand break repair [GO:2000779]; regulation of embryonic development [GO:0045995]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006511; GO:0006974; GO:0016607; GO:0043161; GO:0045995; GO:0046966; GO:0061630; GO:0140861; GO:1901315; GO:2000779; GO:2000780 26946 FUN_041556 1609 775 602 1160 965 NA NA NA NA NA NA NA 26947 FUN_041551 10707 6320 5491 7988 6505 NA NA NA NA NA NA NA 26948 FUN_041550 88 23 46 76 41 NA NA NA NA NA NA NA 26949 FUN_041553 477 235 117 214 133 NA NA NA NA NA NA NA 26950 FUN_033119 0 8 18 0 0 ptg000023l:40140144-40143110 Q1PSW8 2.93e-84 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 26951 FUN_033110 7 0 0 0 0 NA NA NA NA NA NA NA 26952 FUN_033111 0 0 3 6 0 NA NA NA NA NA NA NA 26953 FUN_033112 21 1 96 71 173 NA NA NA NA NA NA NA 26954 FUN_033114 3092 1998 1337 2942 1657 NA NA NA NA NA NA NA 26955 FUN_033115 1445 1359 907 1857 1432 NA NA NA NA NA NA NA 26956 FUN_033116 53 34 141 17 27 ptg000023l:40094391-40103252 Q96AY4 8.2e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26957 FUN_033116 53 34 141 17 27 ptg000023l:40094391-40103252 Q96AY4 1.96e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26958 FUN_033116 53 34 141 17 27 ptg000023l:40094391-40103252 Q96AY4 1.46e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26959 FUN_033116 53 34 141 17 27 ptg000023l:40094391-40103252 Q96AY4 9.93e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26960 FUN_033116 53 34 141 17 27 ptg000023l:40094391-40103252 Q96AY4 7.98e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26961 FUN_033116 53 34 141 17 27 ptg000023l:40094391-40103252 Q96AY4 1.79e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26962 FUN_033117 8 29 16 60 19 ptg000023l:40109780-40117589 Q96AY4 1.19e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26963 FUN_033117 8 29 16 60 19 ptg000023l:40109780-40117589 Q96AY4 9.7e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26964 FUN_033117 8 29 16 60 19 ptg000023l:40109780-40117589 Q96AY4 2.84e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26965 FUN_033117 8 29 16 60 19 ptg000023l:40109780-40117589 Q96AY4 2.83e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26966 FUN_033117 8 29 16 60 19 ptg000023l:40109780-40117589 Q96AY4 1.49e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26967 FUN_033117 8 29 16 60 19 ptg000023l:40109780-40117589 Q96AY4 6.83e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 26968 FUN_039897 330 143 190 509 190 ptg000031l:1500174-1504517 Q9QZU7 7.56e-21 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 26969 FUN_028899 30 0 13 17 0 NA NA NA NA NA NA NA 26970 FUN_028898 68 47 29 53 20 NA NA NA NA NA NA NA 26971 FUN_042924 11 13 0 0 18 NA NA NA NA NA NA NA 26972 FUN_003588 44 0 17 0 19 NA NA NA NA NA NA NA 26973 FUN_042920 2659 4055 2021 3598 1813 NA NA NA NA NA NA NA 26974 FUN_003585 817 292 233 253 598 ntLink_8:12957967-13027581 Q9NBX4 4.9e-27 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26975 FUN_003585 817 292 233 253 598 ntLink_8:12957967-13027581 Q9NBX4 4.9e-27 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 26976 FUN_042929 2 266 14 4 467 NA NA NA NA NA NA NA 26977 FUN_003581 0 0 0 0 13 NA NA NA NA NA NA NA 26978 FUN_028893 794 708 410 865 430 ptg000022l:5651757-5654905 P78381 5.91e-40 UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT) Homo sapiens (Human) carbohydrate transport [GO:0008643]; galactose metabolic process [GO:0006012]; UDP-galactose transmembrane transport [GO:0072334] GO:0000139; GO:0005459; GO:0005654; GO:0005783; GO:0005794; GO:0006012; GO:0008643; GO:0072334 26979 FUN_033759 1900 952 741 2284 1692 ptg000024l:1059018-1082879 Q28005 3.2e-91 Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (Luteinizing hormone receptor) (LSH-R) Bos taurus (Bovine) activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to luteinizing hormone stimulus [GO:0071373]; hormone-mediated signaling pathway [GO:0009755]; luteinizing hormone signaling pathway [GO:0042700]; male gonad development [GO:0008584]; ovarian follicle development [GO:0001541]; ovulation cycle process [GO:0022602]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200] GO:0001541; GO:0004964; GO:0005886; GO:0007189; GO:0007190; GO:0007200; GO:0008528; GO:0008584; GO:0009755; GO:0022602; GO:0042700; GO:0071373 26980 FUN_040202 11 3 25 9 17 NA NA NA NA NA NA NA 26981 FUN_040203 2484 3127 1109 1335 541 NA NA NA NA NA NA NA 26982 FUN_040200 200 0 0 13 0 NA NA NA NA NA NA NA 26983 FUN_040206 14156 13640 4893 8012 6117 NA NA NA NA NA NA NA 26984 FUN_040207 195 112 0 54 31 NA NA NA NA NA NA NA 26985 FUN_040204 3879 4473 1893 3206 1887 NA NA NA NA NA NA NA 26986 FUN_040208 2 0 3 9 0 NA NA NA NA NA NA NA 26987 FUN_040209 1263 795 507 593 627 ptg000031l:5493441-5521221 O08523 1.9e-24 Alpha-tectorin Mus musculus (Mouse) cell-matrix adhesion [GO:0007160]; sensory perception of sound [GO:0007605] GO:0005201; GO:0005576; GO:0005886; GO:0007160; GO:0007605; GO:0031012 26988 FUN_034461 0 0 0 0 31 NA NA NA NA NA NA NA 26989 FUN_034460 199 115 192 356 566 NA NA NA NA NA NA NA 26990 FUN_034463 0 0 3 0 6 NA NA NA NA NA NA NA 26991 FUN_034462 48 0 24 0 187 NA NA NA NA NA NA NA 26992 FUN_034464 4 0 3 3 8 NA NA NA NA NA NA NA 26993 FUN_034466 4 0 6 4 4 NA NA NA NA NA NA NA 26994 FUN_001955 741 608 516 713 560 NA NA NA NA NA NA NA 26995 FUN_011471 8 0 18 6 85 NA NA NA NA NA NA NA 26996 FUN_011659 37 136 29 90 271 NA NA NA NA NA NA NA 26997 FUN_001352 75 70 0 25 74 NA NA NA NA NA NA NA 26998 FUN_014519 0 0 18 2 12 NA NA NA NA NA NA NA 26999 FUN_014518 66 15 18 13 39 NA NA NA NA NA NA NA 27000 FUN_014513 4205 6334 4961 4749 4785 NA NA NA NA NA NA NA 27001 FUN_014512 8030 6236 3759 6778 4881 NA NA NA NA NA NA NA 27002 FUN_014511 1041 741 934 1219 1044 NA NA NA NA NA NA NA 27003 FUN_014510 2380 1686 1144 2050 1459 NA NA NA NA NA NA NA 27004 FUN_014517 5127 3307 2196 3915 3961 ptg000009l:850414-880912 Q5RHH4 7.08e-31 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 27005 FUN_014517 5127 3307 2196 3915 3961 ptg000009l:850414-880912 Q5RHH4 7.08e-31 Intraflagellar transport protein 172 homolog Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; intraciliary transport [GO:0042073]; photoreceptor cell maintenance [GO:0045494]; pronephros development [GO:0048793]; regulation of TOR signaling [GO:0032006]; retina development in camera-type eye [GO:0060041] GO:0005929; GO:0005930; GO:0030992; GO:0032006; GO:0036064; GO:0042073; GO:0045494; GO:0048793; GO:0060041; GO:0060271 27006 FUN_014516 38 0 17 20 64 NA NA NA NA NA NA NA 27007 FUN_014515 939 643 742 600 945 ptg000009l:827425-834089 Q803K4 2.6e-22 N-lysine methyltransferase setd6 (EC 2.1.1.-) (SET domain-containing protein 6) Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of NF-kappaB transcription factor activity [GO:0032088]; peptidyl-lysine monomethylation [GO:0018026]; regulation of inflammatory response [GO:0050727] GO:0005634; GO:0016279; GO:0018026; GO:0032088; GO:0050727 27008 FUN_014514 3248 3936 886 1900 1050 NA NA NA NA NA NA NA 27009 FUN_013725 6 7 0 157 0 NA NA NA NA NA NA NA 27010 FUN_013724 0 6 0 0 0 NA NA NA NA NA NA NA 27011 FUN_013726 0 0 0 19 7 NA NA NA NA NA NA NA 27012 FUN_013720 0 0 0 0 11 NA NA NA NA NA NA NA 27013 FUN_013723 0 0 0 0 13 NA NA NA NA NA NA NA 27014 FUN_040070 1733 927 910 996 718 NA NA NA NA NA NA NA 27015 FUN_029489 36 33 42 54 33 NA NA NA NA NA NA NA 27016 FUN_029488 0 0 0 3 8 NA NA NA NA NA NA NA 27017 FUN_029483 0 2 18 4 9 NA NA NA NA NA NA NA 27018 FUN_029485 1171 979 504 904 646 NA NA NA NA NA NA NA 27019 FUN_029484 1199 1095 498 735 724 NA NA NA NA NA NA NA 27020 FUN_029487 44 29 32 54 85 NA NA NA NA NA NA NA 27021 FUN_029486 911 1109 858 808 870 NA NA NA NA NA NA NA 27022 FUN_026370 4113 1394 1688 3235 716 ptg000020l:8145486-8157800 P21328 2.06e-38 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 27023 FUN_018249 86 52 88 245 182 NA NA NA NA NA NA NA 27024 FUN_026376 3 4 1 0 14 NA NA NA NA NA NA NA 27025 FUN_026377 367 241 125 233 174 NA NA NA NA NA NA NA 27026 FUN_026374 551 637 195 266 626 ptg000020l:8176636-8179476 Q39056 3.59e-50 Cyclic pyranopterin monophosphate synthase, mitochondrial (EC 4.6.1.17) (Molybdenum cofactor biosynthesis enzyme CNX3) (Molybdenum cofactor biosynthesis protein C) (Molybdopterin biosynthesis protein CNX3) Arabidopsis thaliana (Mouse-ear cress) Mo-molybdopterin cofactor biosynthetic process [GO:0006777] GO:0005739; GO:0005759; GO:0006777; GO:0009507; GO:0061799 27027 FUN_019614 0 0 0 0 34 NA NA NA NA NA NA NA 27028 FUN_026378 582 828 280 346 450 NA NA NA NA NA NA NA 27029 FUN_026379 560 379 327 595 262 ptg000020l:8202992-8204129 P56223 1.28e-30 POU domain, class 6, transcription factor 1 (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5) Rattus norvegicus (Rat) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0003677; GO:0005634; GO:0006357; GO:0043565; GO:1990837 27030 FUN_040072 1267 1008 840 1102 380 ptg000031l:3857340-3866475 Q6PB70 2.76e-29 Anoctamin-8 (Transmembrane protein 16H) Mus musculus (Mouse) chloride transport [GO:0006821]; transmembrane transport [GO:0055085] GO:0005886; GO:0006821; GO:0055085 27031 FUN_022871 1434 833 605 977 601 ptg000017l:907456-909940 A6NCS4 4.63e-36 Homeobox protein Nkx-2.6 (Homeobox protein NK-2 homolog F) Homo sapiens (Human) atrial cardiac muscle cell development [GO:0055014]; cell differentiation [GO:0030154]; digestive tract development [GO:0048565]; embryonic heart tube development [GO:0035050]; epithelial cell apoptotic process [GO:1904019]; epithelial cell differentiation [GO:0030855]; epithelial cell proliferation [GO:0050673]; hypothalamus development [GO:0021854]; negative regulation of apoptotic process [GO:0043066]; negative regulation of epithelial cell apoptotic process [GO:1904036]; pericardium development [GO:0060039]; pharyngeal system development [GO:0060037]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; tongue development [GO:0043586]; ventricular cardiac muscle cell development [GO:0055015] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0008284; GO:0021854; GO:0030154; GO:0030855; GO:0035050; GO:0043066; GO:0043586; GO:0045944; GO:0048565; GO:0050673; GO:0050679; GO:0055014; GO:0055015; GO:0060037; GO:0060039; GO:1904019; GO:1904036 27032 FUN_022870 132 7 30 135 66 ptg000017l:903479-904337 P97503 5.9e-34 Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) (Homeobox protein NK-3 homolog B) Mus musculus (Mouse) animal organ development [GO:0048513]; animal organ formation [GO:0048645]; cell differentiation [GO:0030154]; determination of left/right symmetry [GO:0007368]; digestive system development [GO:0055123]; embryonic skeletal system development [GO:0048706]; intestinal epithelial cell development [GO:0060576]; middle ear morphogenesis [GO:0042474]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of transcription by RNA polymerase II [GO:0000122]; pancreas development [GO:0031016]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; spleen development [GO:0048536] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0001501; GO:0005634; GO:0005654; GO:0006357; GO:0007368; GO:0030154; GO:0031016; GO:0032331; GO:0042474; GO:0043066; GO:0048513; GO:0048536; GO:0048645; GO:0048705; GO:0048706; GO:0055123; GO:0060576; GO:1990837 27033 FUN_022873 152 32 32 56 57 ptg000017l:942960-943967 P52953 2.35e-35 Homeobox protein MSX-2 (Homeobox protein Hox-8-1) Rattus norvegicus (Rat) activation of meiosis [GO:0090427]; anterior/posterior pattern specification [GO:0009952]; BMP signaling pathway [GO:0030509]; BMP signaling pathway involved in heart development [GO:0061312]; bone morphogenesis [GO:0060349]; bone trabecula formation [GO:0060346]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cartilage development [GO:0051216]; cellular response to estradiol stimulus [GO:0071392]; cellular response to growth factor stimulus [GO:0071363]; chondrocyte development [GO:0002063]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; embryonic hindlimb morphogenesis [GO:0035116]; embryonic limb morphogenesis [GO:0030326]; embryonic morphogenesis [GO:0048598]; embryonic nail plate morphogenesis [GO:0035880]; enamel mineralization [GO:0070166]; endochondral bone growth [GO:0003416]; epithelial to mesenchymal transition involved in endocardial cushion formation [GO:0003198]; frontal suture morphogenesis [GO:0060364]; mammary gland epithelium development [GO:0061180]; mesenchymal cell apoptotic process [GO:0097152]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of CREB transcription factor activity [GO:0032792]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of keratinocyte differentiation [GO:0045617]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription regulatory region DNA binding [GO:2000678]; odontogenesis [GO:0042476]; ossification [GO:0001503]; osteoblast development [GO:0002076]; osteoblast differentiation [GO:0001649]; outflow tract morphogenesis [GO:0003151]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of apoptotic process [GO:0043065]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of cell death [GO:0010942]; positive regulation of mesenchymal cell apoptotic process [GO:2001055]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of timing of catagen [GO:0051795]; regulation of apoptotic process [GO:0042981]; regulation of transcription by RNA polymerase II [GO:0006357]; signal transduction involved in regulation of gene expression [GO:0023019]; stem cell differentiation [GO:0048863]; transcription by RNA polymerase II [GO:0006366]; wound healing [GO:0042060]; wound healing, spreading of epidermal cells [GO:0035313] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0001503; GO:0001649; GO:0002063; GO:0002076; GO:0003148; GO:0003151; GO:0003198; GO:0003416; GO:0003677; GO:0005634; GO:0005667; GO:0006357; GO:0006366; GO:0008285; GO:0009952; GO:0010942; GO:0023019; GO:0030326; GO:0030509; GO:0030513; GO:0032792; GO:0035115; GO:0035116; GO:0035313; GO:0035880; GO:0042060; GO:0042476; GO:0042733; GO:0042981; GO:0043065; GO:0043066; GO:0043565; GO:0045599; GO:0045617; GO:0045669; GO:0045892; GO:0048598; GO:0048863; GO:0051216; GO:0051795; GO:0060346; GO:0060349; GO:0060364; GO:0060444; GO:0061180; GO:0061312; GO:0070166; GO:0071363; GO:0071392; GO:0090427; GO:0097152; GO:1990837; GO:2000678; GO:2001055 27034 FUN_022875 53 263 27 571 628 ptg000017l:973406-979393 B8V7S0 2.18e-40 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 27035 FUN_022874 245 113 126 565 271 ptg000017l:959252-969178 B8V7S0 1.98e-41 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 27036 FUN_022877 684 560 345 462 354 ptg000017l:993852-995772 Q9BRF8 4.48e-43 Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1) Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0005886; GO:0017018; GO:0035578; GO:0046872 27037 FUN_022877 684 560 345 462 354 ptg000017l:993852-995772 Q9BRF8 1e-36 Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1) Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0005886; GO:0017018; GO:0035578; GO:0046872 27038 FUN_022876 1053 714 414 1078 815 NA NA NA NA NA NA NA 27039 FUN_022879 1204 882 521 2053 1484 NA NA NA NA NA NA NA 27040 FUN_022878 674 652 444 752 534 ptg000017l:1000424-1002381 P48193 5.91e-32 Protein 4.1 (P4.1) (4.1R) (Band 4.1) (Erythrocyte membrane protein band 4.1) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actomyosin structure organization [GO:0031032]; cell cycle [GO:0007049]; cell division [GO:0051301]; cortical actin cytoskeleton organization [GO:0030866]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to cell cortex [GO:1904778]; protein-containing complex assembly [GO:0065003]; regulation of calcium ion transport [GO:0051924]; regulation of cell shape [GO:0008360]; regulation of intestinal absorption [GO:1904478] GO:0003779; GO:0005198; GO:0005516; GO:0005545; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007049; GO:0008022; GO:0008360; GO:0009898; GO:0014069; GO:0015629; GO:0016020; GO:0016323; GO:0016604; GO:0030036; GO:0030054; GO:0030507; GO:0030863; GO:0030866; GO:0031032; GO:0032092; GO:0032991; GO:0045171; GO:0047485; GO:0051219; GO:0051301; GO:0051924; GO:0065003; GO:0072686; GO:1904478; GO:1904778 27041 FUN_029731 88 108 82 37 0 NA NA NA NA NA NA NA 27042 FUN_029730 0 29 26 20 0 NA NA NA NA NA NA NA 27043 FUN_029737 464 442 68 446 1 NA NA NA NA NA NA NA 27044 FUN_040075 5584 7393 5083 4809 3049 NA NA NA NA NA NA NA 27045 FUN_029739 0 38 0 11 3 NA NA NA NA NA NA NA 27046 FUN_029738 37 32 262 73 0 NA NA NA NA NA NA NA 27047 FUN_023476 99 37 27 18 127 ptg000017l:7940770-7948363 B8VIU6 8.94e-21 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 27048 FUN_023477 34 30 15 18 32 NA NA NA NA NA NA NA 27049 FUN_023474 0 0 0 4 36 NA NA NA NA NA NA NA 27050 FUN_023475 0 15 0 10 0 ptg000017l:7927799-7934487 B8VIU6 1.09e-21 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 27051 FUN_023472 99 19 14 35 6 NA NA NA NA NA NA NA 27052 FUN_023473 0 0 0 0 8 ptg000017l:7912386-7913493 B8VIU6 1.57e-22 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 27053 FUN_023470 98 40 42 31 19 ptg000017l:7871757-7882452 B8VIU6 6.95e-22 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 27054 FUN_023471 0 0 0 13 0 NA NA NA NA NA NA NA 27055 FUN_023478 62 53 72 63 90 NA NA NA NA NA NA NA 27056 FUN_023479 0 0 7 0 0 NA NA NA NA NA NA NA 27057 FUN_039967 334 227 225 331 458 NA NA NA NA NA NA NA 27058 FUN_039966 2986 3102 1620 2749 1694 NA NA NA NA NA NA NA 27059 FUN_039965 342 454 252 366 301 ptg000031l:2204431-2207071 Q90415 2.28e-26 Retinoic acid receptor RXR-alpha-B (Nuclear receptor subfamily 2 group B member 1-B) (Retinoid X receptor alpha-B) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000122; GO:0000978; GO:0003700; GO:0003707; GO:0004879; GO:0006357; GO:0008270; GO:0030154; GO:0032526; GO:0044323; GO:0045944; GO:0048384; GO:0048856; GO:0090575 27060 FUN_039964 0 0 0 0 10 ptg000031l:2198284-2199967 P30543 5.82e-23 Adenosine receptor A2a Rattus norvegicus (Rat) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; apoptotic signaling pathway [GO:0097190]; astrocyte activation [GO:0048143]; eating behavior [GO:0042755]; excitatory postsynaptic potential [GO:0060079]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; inhibitory postsynaptic potential [GO:0060080]; locomotory behavior [GO:0007626]; membrane depolarization [GO:0051899]; negative regulation of alpha-beta T cell activation [GO:0046636]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of inflammatory response [GO:0050728]; negative regulation of locomotion [GO:0040013]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of vascular permeability [GO:0043116]; neuron projection morphogenesis [GO:0048812]; positive regulation of acetylcholine secretion, neurotransmission [GO:0014057]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938]; positive regulation of glutamate secretion [GO:0014049]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of protein secretion [GO:0050714]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of urine volume [GO:0035810]; prepulse inhibition [GO:0060134]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; protein kinase C-activating G protein-coupled receptor signaling pathway [GO:0007205]; regulation of calcium ion transport [GO:0051924]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of norepinephrine secretion [GO:0014061]; response to alkaloid [GO:0043279]; response to amphetamine [GO:0001975]; response to caffeine [GO:0031000]; response to inorganic substance [GO:0010035]; response to purine-containing compound [GO:0014074]; response to xenobiotic stimulus [GO:0009410]; synaptic transmission, cholinergic [GO:0007271]; synaptic transmission, dopaminergic [GO:0001963]; synaptic transmission, glutamatergic [GO:0035249]; vasodilation [GO:0042311] GO:0000139; GO:0001609; GO:0001963; GO:0001973; GO:0001975; GO:0004930; GO:0005886; GO:0006355; GO:0006469; GO:0007186; GO:0007189; GO:0007205; GO:0007271; GO:0007626; GO:0008285; GO:0008289; GO:0009410; GO:0010035; GO:0012505; GO:0014049; GO:0014057; GO:0014061; GO:0014069; GO:0014074; GO:0016020; GO:0019899; GO:0030424; GO:0030425; GO:0030673; GO:0031000; GO:0031802; GO:0032230; GO:0032279; GO:0035249; GO:0035810; GO:0035815; GO:0040013; GO:0042311; GO:0042734; GO:0042755; GO:0042802; GO:0043025; GO:0043116; GO:0043154; GO:0043279; GO:0043524; GO:0044877; GO:0045211; GO:0045938; GO:0046636; GO:0048143; GO:0048786; GO:0048812; GO:0050714; GO:0050728; GO:0051393; GO:0051881; GO:0051899; GO:0051924; GO:0051968; GO:0060079; GO:0060080; GO:0060134; GO:0097190; GO:0098978; GO:0099171; GO:1900273; GO:2001235 27061 FUN_039963 0 2 16 0 0 NA NA NA NA NA NA NA 27062 FUN_039962 0 42 196 0 84 ptg000031l:2185166-2188916 Q96AY4 3.54e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27063 FUN_039962 0 42 196 0 84 ptg000031l:2185166-2188916 Q96AY4 5.62e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27064 FUN_039962 0 42 196 0 84 ptg000031l:2185166-2188916 Q96AY4 1.66e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27065 FUN_039962 0 42 196 0 84 ptg000031l:2185166-2188916 Q96AY4 1.51e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27066 FUN_039961 17 0 20 0 52 NA NA NA NA NA NA NA 27067 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 2.08e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27068 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 1.32e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27069 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 1.97e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27070 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 9.35e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27071 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 2.15e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27072 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 1.22e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27073 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 4.06e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27074 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 2.99e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27075 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 6.19e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27076 FUN_039960 200 155 179 145 127 ptg000031l:2143662-2164591 Q96AY4 1.74e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27077 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.47e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27078 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.47e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27079 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 4.13e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27080 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 4.13e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27081 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 4.13e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27082 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 4.13e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27083 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.53e-45 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27084 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.53e-45 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27085 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.85e-42 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27086 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.85e-42 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27087 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 7.65e-42 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27088 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 7.65e-42 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27089 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 2.8e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27090 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 7.67e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27091 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.12e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27092 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 2.03e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27093 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 2.51e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27094 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 4.79e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27095 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 5.81e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27096 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 7.86e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27097 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 9.23e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27098 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 9.7e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27099 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.87e-22 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27100 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.93e-22 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27101 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 3.31e-22 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27102 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 1.43e-21 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27103 FUN_039969 15623 4234 5832 17440 12316 ptg000031l:2277433-2327637 Q95218 3.07e-21 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 27104 FUN_039968 565 248 193 974 640 NA NA NA NA NA NA NA 27105 FUN_001699 106 52 193 422 97 NA NA NA NA NA NA NA 27106 FUN_014116 200 172 580 344 281 NA NA NA NA NA NA NA 27107 FUN_015396 1218 533 33 184 725 NA NA NA NA NA NA NA 27108 FUN_015397 0 45 69 16 0 NA NA NA NA NA NA NA 27109 FUN_015398 21308 16650 6403 4367 11221 NA NA NA NA NA NA NA 27110 FUN_018516 602 1305 271 1281 2265 NA NA NA NA NA NA NA 27111 FUN_018513 52 32 49 34 0 NA NA NA NA NA NA NA 27112 FUN_018510 69 0 10 0 2 NA NA NA NA NA NA NA 27113 FUN_017729 0 0 5 0 26 ptg000011l:13745402-13745780 P35067 1.64e-82 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27114 FUN_017728 10 0 19 0 40 NA NA NA NA NA NA NA 27115 FUN_018519 1554 3218 1827 1802 1016 NA NA NA NA NA NA NA 27116 FUN_025135 0 0 7 0 55 NA NA NA NA NA NA NA 27117 FUN_025134 0 0 0 0 19 NA NA NA NA NA NA NA 27118 FUN_025136 0 2 0 16 0 NA NA NA NA NA NA NA 27119 FUN_025131 174 21 80 159 193 NA NA NA NA NA NA NA 27120 FUN_025130 905 503 295 859 1086 NA NA NA NA NA NA NA 27121 FUN_025133 43 19 40 88 144 NA NA NA NA NA NA NA 27122 FUN_025132 98 42 52 59 97 NA NA NA NA NA NA NA 27123 FUN_017893 713 479 312 476 402 ptg000012l:1642578-1648871 Q5XIN7 3.76e-25 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 27124 FUN_017893 713 479 312 476 402 ptg000012l:1642578-1648871 Q5XIN7 1.15e-21 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Rattus norvegicus (Rat) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145; GO:0047223 27125 FUN_017892 305 164 179 231 264 NA NA NA NA NA NA NA 27126 FUN_017891 563 391 302 300 233 NA NA NA NA NA NA NA 27127 FUN_017890 897 1058 606 1119 766 ptg000012l:1621439-1630554 Q5RCB9 2.02e-31 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 27128 FUN_017890 897 1058 606 1119 766 ptg000012l:1621439-1630554 Q5RCB9 2.27e-30 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 27129 FUN_017890 897 1058 606 1119 766 ptg000012l:1621439-1630554 Q5RCB9 1.15e-27 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 27130 FUN_017890 897 1058 606 1119 766 ptg000012l:1621439-1630554 Q5RCB9 3.47e-25 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 27131 FUN_017890 897 1058 606 1119 766 ptg000012l:1621439-1630554 Q5RCB9 6.25e-23 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 27132 FUN_017897 1459 2311 937 1929 1104 ptg000012l:1669064-1675651 Q00532 9.03e-29 Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein kinase KKIALRE) Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017] GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006468; GO:0035869; GO:0043231; GO:0070062; GO:0106310; GO:1902017 27133 FUN_017897 1459 2311 937 1929 1104 ptg000012l:1669064-1675651 Q00532 2.69e-22 Cyclin-dependent kinase-like 1 (EC 2.7.11.22) (Protein kinase p42 KKIALRE) (Serine/threonine-protein kinase KKIALRE) Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of cilium assembly [GO:1902017] GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0006468; GO:0035869; GO:0043231; GO:0070062; GO:0106310; GO:1902017 27134 FUN_025138 43 49 25 87 36 NA NA NA NA NA NA NA 27135 FUN_017895 0 0 0 31 2 NA NA NA NA NA NA NA 27136 FUN_006177 4 3 16 29 6 NA NA NA NA NA NA NA 27137 FUN_024846 53 0 0 20 91 ptg000018l:11651555-11664364 P14381 4.33e-59 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 27138 FUN_024846 53 0 0 20 91 ptg000018l:11651555-11664364 P14381 4.33e-59 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 27139 FUN_024846 53 0 0 20 91 ptg000018l:11651555-11664364 P14381 4.33e-59 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 27140 FUN_024846 53 0 0 20 91 ptg000018l:11651555-11664364 P14381 4.33e-59 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 27141 FUN_024844 0 0 0 12 28 NA NA NA NA NA NA NA 27142 FUN_024842 34 0 13 10 219 NA NA NA NA NA NA NA 27143 FUN_024843 0 0 0 0 18 NA NA NA NA NA NA NA 27144 FUN_016155 3 3 38 7 58 NA NA NA NA NA NA NA 27145 FUN_016154 1177 413 393 771 406 NA NA NA NA NA NA NA 27146 FUN_019644 0 9 0 0 9 NA NA NA NA NA NA NA 27147 FUN_019647 63 24 57 18 53 NA NA NA NA NA NA NA 27148 FUN_044192 2 0 6 5 10 NA NA NA NA NA NA NA 27149 FUN_044193 3 6 31 29 96 NA NA NA NA NA NA NA 27150 FUN_019642 0 0 9 2 0 NA NA NA NA NA NA NA 27151 FUN_019643 13 0 15 0 91 NA NA NA NA NA NA NA 27152 FUN_042271 946 874 868 834 1432 NA NA NA NA NA NA NA 27153 FUN_035289 371 218 114 288 146 NA NA NA NA NA NA NA 27154 FUN_019648 0 0 37 0 56 NA NA NA NA NA NA NA 27155 FUN_019649 2 0 67 4 91 NA NA NA NA NA NA NA 27156 FUN_044199 2 1 6 0 32 NA NA NA NA NA NA NA 27157 FUN_010768 153 122 81 53 206 ptg000007l:2601088-2602114 E7F7V7 8.38e-24 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 27158 FUN_023089 113 606 181 148 153 ptg000017l:3500114-3501140 O02813 3.51e-21 Neuropeptide Y receptor type 1 (NPY1-R) Canis lupus familiaris (Dog) (Canis familiaris) feeding behavior [GO:0007631]; glucose metabolic process [GO:0006006]; locomotory behavior [GO:0007626]; outflow tract morphogenesis [GO:0003151]; regulation of blood pressure [GO:0008217]; regulation of multicellular organism growth [GO:0040014]; sensory perception of pain [GO:0019233] GO:0001601; GO:0001602; GO:0003151; GO:0005886; GO:0006006; GO:0007626; GO:0007631; GO:0008188; GO:0008217; GO:0019233; GO:0040014; GO:0042923; GO:0043005 27159 FUN_028238 2139 1097 1467 4199 1754 ptg000021l:17238231-17244755 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27160 FUN_028238 2139 1097 1467 4199 1754 ptg000021l:17238231-17244755 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27161 FUN_028238 2139 1097 1467 4199 1754 ptg000021l:17238231-17244755 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27162 FUN_028238 2139 1097 1467 4199 1754 ptg000021l:17238231-17244755 Q96AY4 1.17e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27163 FUN_028238 2139 1097 1467 4199 1754 ptg000021l:17238231-17244755 Q96AY4 3.31e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27164 FUN_016152 1074 278 490 781 646 ptg000010l:2162029-2172786 Q8BHD8 3.46e-24 Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 Mus musculus (Mouse) NA GO:0004719; GO:0005737 27165 FUN_024268 222 116 49 210 76 ptg000018l:4168636-4174569 P59046 1.14e-32 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 27166 FUN_024269 54 176 171 193 162 NA NA NA NA NA NA NA 27167 FUN_024262 0 15 3 35 9 NA NA NA NA NA NA NA 27168 FUN_024263 86 68 89 157 15 NA NA NA NA NA NA NA 27169 FUN_024260 63 44 23 35 5 ptg000018l:4102480-4105734 Q8K3Z0 1.37e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 27170 FUN_024261 0 46 70 63 44 NA NA NA NA NA NA NA 27171 FUN_024266 34 0 69 30 8 NA NA NA NA NA NA NA 27172 FUN_024267 0 0 0 7 14 NA NA NA NA NA NA NA 27173 FUN_024264 73 51 36 51 7 ptg000018l:4132729-4135759 Q7RTR2 1.2e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27174 FUN_024265 15 14 0 0 0 NA NA NA NA NA NA NA 27175 FUN_044228 64 212 79 171 474 NA NA NA NA NA NA NA 27176 FUN_044229 3 6 13 7 122 NA NA NA NA NA NA NA 27177 FUN_030179 0 0 2 0 17 NA NA NA NA NA NA NA 27178 FUN_044220 19 62 31 58 142 NA NA NA NA NA NA NA 27179 FUN_044224 0 0 0 0 7 NA NA NA NA NA NA NA 27180 FUN_030176 19 1615 65 4502 1558 NA NA NA NA NA NA NA 27181 FUN_030175 0 0 12 0 8 NA NA NA NA NA NA NA 27182 FUN_016158 2710 1442 934 2011 1477 NA NA NA NA NA NA NA 27183 FUN_040336 147 107 124 316 119 NA NA NA NA NA NA NA 27184 FUN_038368 59 11 39 20 446 NA NA NA NA NA NA NA 27185 FUN_010761 8 2 1 12 13 NA NA NA NA NA NA NA 27186 FUN_038366 8 0 16 6 59 NA NA NA NA NA NA NA 27187 FUN_038367 0 0 5 8 0 NA NA NA NA NA NA NA 27188 FUN_038364 228 235 158 457 622 ptg000027l:6253892-6260268 Q4GZT3 6.5e-40 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 27189 FUN_038365 67 79 88 85 134 NA NA NA NA NA NA NA 27190 FUN_038362 19 0 4 2 144 NA NA NA NA NA NA NA 27191 FUN_038363 3 11 2 14 20 NA NA NA NA NA NA NA 27192 FUN_038360 0 27 7 23 29 NA NA NA NA NA NA NA 27193 FUN_038361 118 49 98 196 494 NA NA NA NA NA NA NA 27194 FUN_010763 3448 2101 1922 3475 2774 ptg000007l:2507171-2540610 Q7TSU1 3.8e-39 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2) Rattus norvegicus (Rat) endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012] GO:0000139; GO:0001881; GO:0005085; GO:0005737; GO:0005802; GO:0005815; GO:0005829; GO:0005879; GO:0006887; GO:0006893; GO:0007032; GO:0010256; GO:0015031; GO:0016020; GO:0017022; GO:0031410; GO:0032012; GO:0032279; GO:0032280; GO:0032760; GO:0034237; GO:0035556; GO:0043197; GO:0048471; GO:0050811; GO:0055037; GO:0098793; GO:0098794; GO:0098978; GO:0098982 27195 FUN_010763 3448 2101 1922 3475 2774 ptg000007l:2507171-2540610 Q7TSU1 3.8e-39 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2) Rattus norvegicus (Rat) endomembrane system organization [GO:0010256]; endosome organization [GO:0007032]; exocytosis [GO:0006887]; Golgi to plasma membrane transport [GO:0006893]; intracellular signal transduction [GO:0035556]; positive regulation of tumor necrosis factor production [GO:0032760]; protein transport [GO:0015031]; receptor recycling [GO:0001881]; regulation of ARF protein signal transduction [GO:0032012] GO:0000139; GO:0001881; GO:0005085; GO:0005737; GO:0005802; GO:0005815; GO:0005829; GO:0005879; GO:0006887; GO:0006893; GO:0007032; GO:0010256; GO:0015031; GO:0016020; GO:0017022; GO:0031410; GO:0032012; GO:0032279; GO:0032280; GO:0032760; GO:0034237; GO:0035556; GO:0043197; GO:0048471; GO:0050811; GO:0055037; GO:0098793; GO:0098794; GO:0098978; GO:0098982 27196 FUN_028234 28 32 38 0 141 NA NA NA NA NA NA NA 27197 FUN_028237 14 0 9 0 0 NA NA NA NA NA NA NA 27198 FUN_028236 3214 1534 585 1583 1892 NA NA NA NA NA NA NA 27199 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 2.39e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27200 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 2.39e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27201 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.92e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27202 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.92e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27203 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 3.07e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27204 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 3.07e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27205 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.61e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27206 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.61e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27207 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 1.3e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27208 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 3.96e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27209 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 8.88e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27210 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 2.34e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27211 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.86e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27212 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 7.08e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27213 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.57e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27214 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 8.23e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27215 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 1.11e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27216 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 1.9e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27217 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 9.97e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27218 FUN_028694 0 0 12 0 17 ptg000022l:2785056-2793297 Q96AY4 4.28e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27219 FUN_025492 0 0 0 38 0 ptg000019l:3442766-3445991 Q61555 1.2e-22 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 27220 FUN_023000 4132 2276 1898 4195 3622 ptg000017l:2416275-2434114 P22607 1.23e-26 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 27221 FUN_023000 4132 2276 1898 4195 3622 ptg000017l:2416275-2434114 P22607 1.23e-26 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 27222 FUN_040334 129 128 873 345 382 NA NA NA NA NA NA NA 27223 FUN_039181 4 0 0 0 27 NA NA NA NA NA NA NA 27224 FUN_039180 8 0 14 8 70 ptg000027l:15293261-15296106 P35061 2.41e-75 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27225 FUN_040335 76 114 42 91 200 NA NA NA NA NA NA NA 27226 FUN_027769 0 0 0 0 7 NA NA NA NA NA NA NA 27227 FUN_027764 444 189 190 979 661 NA NA NA NA NA NA NA 27228 FUN_027762 43 0 62 22 20 NA NA NA NA NA NA NA 27229 FUN_027763 26 0 124 73 64 ptg000021l:10338567-10344824 Q9QYP1 9.32e-30 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 27230 FUN_027763 26 0 124 73 64 ptg000021l:10338567-10344824 Q9QYP1 1.69e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 27231 FUN_027763 26 0 124 73 64 ptg000021l:10338567-10344824 Q9QYP1 1.47e-26 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 27232 FUN_027763 26 0 124 73 64 ptg000021l:10338567-10344824 Q9QYP1 3.12e-26 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 27233 FUN_027761 6 0 0 0 0 NA NA NA NA NA NA NA 27234 FUN_038589 26 69 16 17 0 NA NA NA NA NA NA NA 27235 FUN_038582 11 17 12 34 92 NA NA NA NA NA NA NA 27236 FUN_038583 158 11 16 52 24 NA NA NA NA NA NA NA 27237 FUN_038580 1209 525 640 1248 1398 NA NA NA NA NA NA NA 27238 FUN_038581 92 32 18 119 0 NA NA NA NA NA NA NA 27239 FUN_038584 0 0 0 0 158 NA NA NA NA NA NA NA 27240 FUN_034326 120 296 67 359 173 NA NA NA NA NA NA NA 27241 FUN_036638 36 83 44 49 14 NA NA NA NA NA NA NA 27242 FUN_034327 2054 3203 2046 1497 976 NA NA NA NA NA NA NA 27243 FUN_036634 0 0 0 0 14 NA NA NA NA NA NA NA 27244 FUN_036633 32 1 45 5 188 NA NA NA NA NA NA NA 27245 FUN_034325 433 541 176 587 427 NA NA NA NA NA NA NA 27246 FUN_037589 921 439 295 460 484 ptg000026l:12054439-12061551 Q2TA25 1.72e-34 Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) Bos taurus (Bovine) centrosome cycle [GO:0007098]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear membrane disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cytokinesis [GO:0032465]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; synaptonemal complex disassembly [GO:0070194] GO:0000070; GO:0000086; GO:0000122; GO:0000132; GO:0000278; GO:0000281; GO:0000287; GO:0000776; GO:0000785; GO:0000795; GO:0000922; GO:0000940; GO:0001578; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005876; GO:0006468; GO:0007094; GO:0007095; GO:0007098; GO:0008017; GO:0010800; GO:0010997; GO:0016321; GO:0016567; GO:0018105; GO:0019901; GO:0030496; GO:0031648; GO:0032436; GO:0032465; GO:0034451; GO:0042802; GO:0043066; GO:0043393; GO:0045143; GO:0045184; GO:0045736; GO:0051081; GO:0051233; GO:0051443; GO:0070194; GO:0071168; GO:0090435; GO:0097431; GO:0106310; GO:1901673; GO:1904668; GO:1904776 27247 FUN_037589 921 439 295 460 484 ptg000026l:12054439-12061551 Q2TA25 1.72e-34 Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) Bos taurus (Bovine) centrosome cycle [GO:0007098]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear membrane disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cytokinesis [GO:0032465]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; synaptonemal complex disassembly [GO:0070194] GO:0000070; GO:0000086; GO:0000122; GO:0000132; GO:0000278; GO:0000281; GO:0000287; GO:0000776; GO:0000785; GO:0000795; GO:0000922; GO:0000940; GO:0001578; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005876; GO:0006468; GO:0007094; GO:0007095; GO:0007098; GO:0008017; GO:0010800; GO:0010997; GO:0016321; GO:0016567; GO:0018105; GO:0019901; GO:0030496; GO:0031648; GO:0032436; GO:0032465; GO:0034451; GO:0042802; GO:0043066; GO:0043393; GO:0045143; GO:0045184; GO:0045736; GO:0051081; GO:0051233; GO:0051443; GO:0070194; GO:0071168; GO:0090435; GO:0097431; GO:0106310; GO:1901673; GO:1904668; GO:1904776 27248 FUN_037589 921 439 295 460 484 ptg000026l:12054439-12061551 Q2TA25 4.1e-30 Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) Bos taurus (Bovine) centrosome cycle [GO:0007098]; establishment of mitotic spindle orientation [GO:0000132]; establishment of protein localization [GO:0045184]; female meiosis chromosome segregation [GO:0016321]; G2/M transition of mitotic cell cycle [GO:0000086]; homologous chromosome segregation [GO:0045143]; microtubule bundle formation [GO:0001578]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; mitotic sister chromatid segregation [GO:0000070]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nuclear membrane disassembly [GO:0051081]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; protein destabilization [GO:0031648]; protein localization to chromatin [GO:0071168]; protein localization to nuclear envelope [GO:0090435]; protein phosphorylation [GO:0006468]; protein ubiquitination [GO:0016567]; regulation of cytokinesis [GO:0032465]; regulation of mitotic spindle assembly [GO:1901673]; regulation of protein binding [GO:0043393]; regulation of protein localization to cell cortex [GO:1904776]; synaptonemal complex disassembly [GO:0070194] GO:0000070; GO:0000086; GO:0000122; GO:0000132; GO:0000278; GO:0000281; GO:0000287; GO:0000776; GO:0000785; GO:0000795; GO:0000922; GO:0000940; GO:0001578; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0005876; GO:0006468; GO:0007094; GO:0007095; GO:0007098; GO:0008017; GO:0010800; GO:0010997; GO:0016321; GO:0016567; GO:0018105; GO:0019901; GO:0030496; GO:0031648; GO:0032436; GO:0032465; GO:0034451; GO:0042802; GO:0043066; GO:0043393; GO:0045143; GO:0045184; GO:0045736; GO:0051081; GO:0051233; GO:0051443; GO:0070194; GO:0071168; GO:0090435; GO:0097431; GO:0106310; GO:1901673; GO:1904668; GO:1904776 27249 FUN_037588 192 78 70 161 197 ptg000026l:12038722-12047764 P38935 1.22e-26 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; RNA secondary structure unwinding [GO:0010501] GO:0000049; GO:0003677; GO:0003678; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0008094; GO:0008134; GO:0008186; GO:0008270; GO:0010501; GO:0016020; GO:0016604; GO:0016887; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043139; GO:1990904 27250 FUN_037588 192 78 70 161 197 ptg000026l:12038722-12047764 P38935 2.25e-24 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; RNA secondary structure unwinding [GO:0010501] GO:0000049; GO:0003677; GO:0003678; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0008094; GO:0008134; GO:0008186; GO:0008270; GO:0010501; GO:0016020; GO:0016604; GO:0016887; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043139; GO:1990904 27251 FUN_037588 192 78 70 161 197 ptg000026l:12038722-12047764 P38935 6.74e-22 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2) Homo sapiens (Human) DNA duplex unwinding [GO:0032508]; RNA secondary structure unwinding [GO:0010501] GO:0000049; GO:0003677; GO:0003678; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0008094; GO:0008134; GO:0008186; GO:0008270; GO:0010501; GO:0016020; GO:0016604; GO:0016887; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043139; GO:1990904 27252 FUN_037587 67 54 26 106 47 ptg000026l:12037558-12038256 Q9EQN5 4.08e-22 DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Antifreeze enhancer-binding protein ortholog) (AEP) Rattus norvegicus (Rat) DNA duplex unwinding [GO:0032508]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuromuscular process [GO:0050905]; RNA secondary structure unwinding [GO:0010501]; spinal cord motor neuron differentiation [GO:0021522] GO:0000049; GO:0000122; GO:0003677; GO:0003697; GO:0003723; GO:0003727; GO:0005524; GO:0005634; GO:0005737; GO:0008094; GO:0008186; GO:0008270; GO:0010501; GO:0016887; GO:0021522; GO:0030424; GO:0030426; GO:0032508; GO:0032574; GO:0036121; GO:0042802; GO:0043022; GO:0043025; GO:0043139; GO:0043621; GO:0048471; GO:0050905; GO:1990904; GO:1990955 27253 FUN_034322 4100 3239 1934 3744 3245 NA NA NA NA NA NA NA 27254 FUN_037585 330 126 45 235 231 NA NA NA NA NA NA NA 27255 FUN_037584 666 233 357 411 538 NA NA NA NA NA NA NA 27256 FUN_037583 4391 5807 2090 3848 13028 NA NA NA NA NA NA NA 27257 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 2.05e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27258 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 5.39e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27259 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.23e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27260 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.27e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27261 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.63e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27262 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 6.88e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27263 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.51e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27264 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 2.48e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27265 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.88e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27266 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 2.04e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27267 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 3.89e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27268 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 3.36e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27269 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.2e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27270 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 4.88e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27271 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 7.26e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27272 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 8.31e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27273 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.09e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27274 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.26e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27275 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 2.76e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27276 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.37e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27277 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 2.06e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27278 FUN_018332 382 132 149 1313 560 ptg000012l:7750169-7754233 Q96AY4 1.05e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27279 FUN_034320 115 54 58 69 103 NA NA NA NA NA NA NA 27280 FUN_032418 591 749 341 789 691 ptg000023l:31749097-31750408 Q6DIV6 1.24e-45 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 27281 FUN_036180 370 216 150 314 437 ptg000025l:16110539-16116842 Q3V129 8.35e-82 Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) Mus musculus (Mouse) adult behavior [GO:0030534]; axoneme assembly [GO:0035082]; brain development [GO:0007420]; central nervous system myelination [GO:0022010]; cerebrospinal fluid circulation [GO:0090660]; ciliary basal body organization [GO:0032053]; corpus callosum development [GO:0022038]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; GABAergic neuron differentiation [GO:0097154]; gene expression [GO:0010467]; microtubule cytoskeleton organization [GO:0000226]; motile cilium assembly [GO:0044458]; neurogenesis [GO:0022008]; neuroinflammatory response [GO:0150076]; neuronal stem cell division [GO:0036445]; protein phosphorylation [GO:0006468]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036]; social behavior [GO:0035176]; ventricular system development [GO:0021591] GO:0000226; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0007420; GO:0010467; GO:0010975; GO:0021591; GO:0022008; GO:0022010; GO:0022038; GO:0030534; GO:0032053; GO:0035082; GO:0035176; GO:0036445; GO:0043408; GO:0044458; GO:0046328; GO:0051649; GO:0090036; GO:0090660; GO:0097154; GO:0106310; GO:0150076; GO:1900744; GO:2001222 27282 FUN_036180 370 216 150 314 437 ptg000025l:16110539-16116842 Q3V129 2.56e-64 Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) Mus musculus (Mouse) adult behavior [GO:0030534]; axoneme assembly [GO:0035082]; brain development [GO:0007420]; central nervous system myelination [GO:0022010]; cerebrospinal fluid circulation [GO:0090660]; ciliary basal body organization [GO:0032053]; corpus callosum development [GO:0022038]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; GABAergic neuron differentiation [GO:0097154]; gene expression [GO:0010467]; microtubule cytoskeleton organization [GO:0000226]; motile cilium assembly [GO:0044458]; neurogenesis [GO:0022008]; neuroinflammatory response [GO:0150076]; neuronal stem cell division [GO:0036445]; protein phosphorylation [GO:0006468]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036]; social behavior [GO:0035176]; ventricular system development [GO:0021591] GO:0000226; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0007420; GO:0010467; GO:0010975; GO:0021591; GO:0022008; GO:0022010; GO:0022038; GO:0030534; GO:0032053; GO:0035082; GO:0035176; GO:0036445; GO:0043408; GO:0044458; GO:0046328; GO:0051649; GO:0090036; GO:0090660; GO:0097154; GO:0106310; GO:0150076; GO:1900744; GO:2001222 27283 FUN_036180 370 216 150 314 437 ptg000025l:16110539-16116842 Q3V129 2.11e-26 Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4) Mus musculus (Mouse) adult behavior [GO:0030534]; axoneme assembly [GO:0035082]; brain development [GO:0007420]; central nervous system myelination [GO:0022010]; cerebrospinal fluid circulation [GO:0090660]; ciliary basal body organization [GO:0032053]; corpus callosum development [GO:0022038]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; GABAergic neuron differentiation [GO:0097154]; gene expression [GO:0010467]; microtubule cytoskeleton organization [GO:0000226]; motile cilium assembly [GO:0044458]; neurogenesis [GO:0022008]; neuroinflammatory response [GO:0150076]; neuronal stem cell division [GO:0036445]; protein phosphorylation [GO:0006468]; regulation of JNK cascade [GO:0046328]; regulation of MAPK cascade [GO:0043408]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of p38MAPK cascade [GO:1900744]; regulation of protein kinase C signaling [GO:0090036]; social behavior [GO:0035176]; ventricular system development [GO:0021591] GO:0000226; GO:0003351; GO:0004674; GO:0005524; GO:0005576; GO:0006468; GO:0007420; GO:0010467; GO:0010975; GO:0021591; GO:0022008; GO:0022010; GO:0022038; GO:0030534; GO:0032053; GO:0035082; GO:0035176; GO:0036445; GO:0043408; GO:0044458; GO:0046328; GO:0051649; GO:0090036; GO:0090660; GO:0097154; GO:0106310; GO:0150076; GO:1900744; GO:2001222 27284 FUN_036181 3440 2549 1682 3350 2110 ptg000025l:16120336-16133328 E6ZIJ1 7.25e-26 RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (Heme-oxidized IRP2 ubiquitin ligase 1 homolog) (HOIL-1) (Heme-oxidized IRP2 ubiquitin transferase 1 homolog) Dicentrarchus labrax (European seabass) (Morone labrax) defense response to bacterium [GO:0042742]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; protein linear polyubiquitination [GO:0097039] GO:0016740; GO:0042742; GO:0043123; GO:0043130; GO:0046872; GO:0071797; GO:0097039 27285 FUN_036182 1562 1461 906 1658 1736 NA NA NA NA NA NA NA 27286 FUN_036183 2824 833 937 2594 2165 NA NA NA NA NA NA NA 27287 FUN_036184 8 18 0 12 0 NA NA NA NA NA NA NA 27288 FUN_036185 132 127 37 136 159 NA NA NA NA NA NA NA 27289 FUN_036187 0 0 30 28 29 NA NA NA NA NA NA NA 27290 FUN_036188 1609 1070 767 1204 1152 NA NA NA NA NA NA NA 27291 FUN_036189 249 115 101 403 402 NA NA NA NA NA NA NA 27292 FUN_030500 5 0 1 0 27 ptg000023l:11017504-11020044 P84239 4.17e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27293 FUN_027189 0 0 0 7 20 NA NA NA NA NA NA NA 27294 FUN_027182 28 0 0 0 0 NA NA NA NA NA NA NA 27295 FUN_027180 0 0 0 0 14 NA NA NA NA NA NA NA 27296 FUN_006770 580 1614 668 2321 1446 NA NA NA NA NA NA NA 27297 FUN_006771 379 987 746 383 332 NA NA NA NA NA NA NA 27298 FUN_006772 22 0 0 0 1 NA NA NA NA NA NA NA 27299 FUN_006773 399 170 153 197 158 NA NA NA NA NA NA NA 27300 FUN_006774 539 372 278 310 119 NA NA NA NA NA NA NA 27301 FUN_006775 2107 1198 967 1041 933 NA NA NA NA NA NA NA 27302 FUN_006776 1158 962 610 958 1321 NA NA NA NA NA NA NA 27303 FUN_006777 1382 759 841 1407 828 NA NA NA NA NA NA NA 27304 FUN_006778 2751 1919 1024 1310 392 NA NA NA NA NA NA NA 27305 FUN_006779 61 110 9 156 136 NA NA NA NA NA NA NA 27306 FUN_035757 20 0 41 2 10 NA NA NA NA NA NA NA 27307 FUN_032695 483 78 255 134 653 NA NA NA NA NA NA NA 27308 FUN_026567 18 12 0 0 31 NA NA NA NA NA NA NA 27309 FUN_026565 1755 690 1435 2506 2966 NA NA NA NA NA NA NA 27310 FUN_013426 35 50 3 0 68 NA NA NA NA NA NA NA 27311 FUN_026564 0 0 0 17 52 NA NA NA NA NA NA NA 27312 FUN_028507 1627 428 1203 1649 1455 ptg000021l:20806281-20808840 P50429 1.26e-36 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 27313 FUN_028507 1627 428 1203 1649 1455 ptg000021l:20806281-20808840 P50429 1.26e-36 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 27314 FUN_028507 1627 428 1203 1649 1455 ptg000021l:20806281-20808840 P50429 1.03e-30 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 27315 FUN_028507 1627 428 1203 1649 1455 ptg000021l:20806281-20808840 P50429 1.03e-30 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 27316 FUN_028507 1627 428 1203 1649 1455 ptg000021l:20806281-20808840 P50429 3.93e-23 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 27317 FUN_026561 27 0 18 0 60 NA NA NA NA NA NA NA 27318 FUN_028504 4229 3514 2326 3490 3704 ptg000021l:20773415-20792346 Q14692 4.03e-25 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 27319 FUN_028504 4229 3514 2326 3490 3704 ptg000021l:20773415-20792346 Q14692 3.66e-22 Ribosome biogenesis protein BMS1 homolog (Ribosome assembly protein BMS1 homolog) Homo sapiens (Human) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000479]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462] GO:0000462; GO:0000479; GO:0003723; GO:0003924; GO:0005524; GO:0005525; GO:0005654; GO:0005694; GO:0005730; GO:0030686; GO:0034511 27320 FUN_028692 91 9 17 319 60 NA NA NA NA NA NA NA 27321 FUN_001203 37 95 0 18 3 NA NA NA NA NA NA NA 27322 FUN_001206 141 486 302 447 328 NA NA NA NA NA NA NA 27323 FUN_001209 956 654 314 763 690 NA NA NA NA NA NA NA 27324 FUN_001208 3147 2806 1535 2605 2048 NA NA NA NA NA NA NA 27325 FUN_031456 135 124 147 0 88 NA NA NA NA NA NA NA 27326 FUN_036487 0 0 0 0 52 NA NA NA NA NA NA NA 27327 FUN_025035 1970 1571 687 1384 1520 NA NA NA NA NA NA NA 27328 FUN_031453 0 0 0 0 8 NA NA NA NA NA NA NA 27329 FUN_036480 2037 1427 1400 2595 1781 ptg000025l:18623820-18667829 Q80W93 1.36e-45 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 27330 FUN_036480 2037 1427 1400 2595 1781 ptg000025l:18623820-18667829 Q80W93 1.46e-22 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 27331 FUN_036480 2037 1427 1400 2595 1781 ptg000025l:18623820-18667829 Q80W93 1.13e-21 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 27332 FUN_036480 2037 1427 1400 2595 1781 ptg000025l:18623820-18667829 Q80W93 4.64e-21 Hydrocephalus-inducing protein (Protein Hy-3) Mus musculus (Mouse) axonemal central apparatus assembly [GO:1904158]; brain development [GO:0007420]; cilium movement [GO:0003341]; epithelial cell development [GO:0002064]; trachea development [GO:0060438]; ventricular system development [GO:0021591] GO:0002064; GO:0003341; GO:0005930; GO:0007420; GO:0021591; GO:0060438; GO:1904158; GO:1990716; GO:1990718 27333 FUN_031451 2 15 44 20 2 NA NA NA NA NA NA NA 27334 FUN_022022 0 0 17 96 7 NA NA NA NA NA NA NA 27335 FUN_031450 235 228 71 148 37 NA NA NA NA NA NA NA 27336 FUN_025032 53 107 61 443 241 NA NA NA NA NA NA NA 27337 FUN_025033 119 27 101 136 233 NA NA NA NA NA NA NA 27338 FUN_025856 103 161 143 267 263 ptg000020l:1337771-1342704 Q7RTR2 2.41e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27339 FUN_025857 57 3 81 47 45 ptg000020l:1353825-1358453 Q7RTR2 4.36e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27340 FUN_025854 0 27 43 40 59 NA NA NA NA NA NA NA 27341 FUN_025855 514 198 137 384 327 ptg000020l:1313648-1318092 Q7RTR2 5.57e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27342 FUN_025850 467 25 111 105 1200 ptg000020l:1275802-1288799 Q7RTR2 1.88e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27343 FUN_025851 24 3 58 49 32 ptg000020l:1299894-1302301 C6FG12 3.42e-27 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 27344 FUN_025858 0 0 0 40 0 NA NA NA NA NA NA NA 27345 FUN_025859 782 284 202 385 487 ptg000020l:1368383-1375263 Q7RTR2 5.58e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27346 FUN_019457 36 0 0 67 166 NA NA NA NA NA NA NA 27347 FUN_019456 72 54 2 39 0 NA NA NA NA NA NA NA 27348 FUN_007919 3595 2423 2013 4003 3912 NA NA NA NA NA NA NA 27349 FUN_007918 529 288 229 303 299 ptg000002l:6179674-6181875 Q9D6X6 9.54e-24 Serine protease 23 (EC 3.4.21.-) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0005634; GO:0006508 27350 FUN_018258 890 196 500 1215 1068 NA NA NA NA NA NA NA 27351 FUN_018259 0 0 0 0 11 NA NA NA NA NA NA NA 27352 FUN_007911 146 116 38 86 153 NA NA NA NA NA NA NA 27353 FUN_018250 0 0 4 8 6 NA NA NA NA NA NA NA 27354 FUN_018251 586 649 561 1471 1288 NA NA NA NA NA NA NA 27355 FUN_007914 2069 3401 1727 2115 987 NA NA NA NA NA NA NA 27356 FUN_022490 55 15 6 41 48 NA NA NA NA NA NA NA 27357 FUN_003715 83 21 16 13 38 NA NA NA NA NA NA NA 27358 FUN_019450 7 0 46 101 229 NA NA NA NA NA NA NA 27359 FUN_034111 1360 1112 535 1187 943 NA NA NA NA NA NA NA 27360 FUN_034110 2518 2014 1214 1533 917 NA NA NA NA NA NA NA 27361 FUN_034113 1406 988 790 1337 1730 ptg000024l:5016801-5018103 Q178L7 2.78e-21 Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; protein-FAD linkage [GO:0018293] GO:0005739; GO:0005759; GO:0006121; GO:0018293 27362 FUN_034112 5324 5234 3226 3785 2660 NA NA NA NA NA NA NA 27363 FUN_034115 19 0 0 42 41 ptg000024l:5043346-5052708 Q8BJ56 5.58e-26 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 27364 FUN_034115 19 0 0 42 41 ptg000024l:5043346-5052708 Q8BJ56 1.88e-23 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 27365 FUN_034114 741 394 389 561 696 ptg000024l:5018765-5039564 P28340 1.14e-42 DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125) Homo sapiens (Human) base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA biosynthetic process [GO:0071897]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to UV [GO:0009411] GO:0000109; GO:0000166; GO:0000731; GO:0003677; GO:0003682; GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0005829; GO:0006260; GO:0006261; GO:0006281; GO:0006287; GO:0006297; GO:0008296; GO:0009411; GO:0016020; GO:0016235; GO:0019899; GO:0034644; GO:0043625; GO:0045004; GO:0046872; GO:0051539; GO:0055089; GO:0070987; GO:0071897 27366 FUN_034114 741 394 389 561 696 ptg000024l:5018765-5039564 P28340 1.48e-29 DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125) Homo sapiens (Human) base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA biosynthetic process [GO:0071897]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to UV [GO:0009411] GO:0000109; GO:0000166; GO:0000731; GO:0003677; GO:0003682; GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0005829; GO:0006260; GO:0006261; GO:0006281; GO:0006287; GO:0006297; GO:0008296; GO:0009411; GO:0016020; GO:0016235; GO:0019899; GO:0034644; GO:0043625; GO:0045004; GO:0046872; GO:0051539; GO:0055089; GO:0070987; GO:0071897 27367 FUN_034114 741 394 389 561 696 ptg000024l:5018765-5039564 P28340 2.4e-23 DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125) Homo sapiens (Human) base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA biosynthetic process [GO:0071897]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to UV [GO:0009411] GO:0000109; GO:0000166; GO:0000731; GO:0003677; GO:0003682; GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0005829; GO:0006260; GO:0006261; GO:0006281; GO:0006287; GO:0006297; GO:0008296; GO:0009411; GO:0016020; GO:0016235; GO:0019899; GO:0034644; GO:0043625; GO:0045004; GO:0046872; GO:0051539; GO:0055089; GO:0070987; GO:0071897 27368 FUN_034114 741 394 389 561 696 ptg000024l:5018765-5039564 P28340 1.45e-22 DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125) Homo sapiens (Human) base-excision repair, gap-filling [GO:0006287]; cellular response to UV [GO:0034644]; DNA biosynthetic process [GO:0071897]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA replication proofreading [GO:0045004]; DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; error-free translesion synthesis [GO:0070987]; fatty acid homeostasis [GO:0055089]; nucleotide-excision repair, DNA gap filling [GO:0006297]; response to UV [GO:0009411] GO:0000109; GO:0000166; GO:0000731; GO:0003677; GO:0003682; GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0005829; GO:0006260; GO:0006261; GO:0006281; GO:0006287; GO:0006297; GO:0008296; GO:0009411; GO:0016020; GO:0016235; GO:0019899; GO:0034644; GO:0043625; GO:0045004; GO:0046872; GO:0051539; GO:0055089; GO:0070987; GO:0071897 27369 FUN_034117 989 735 299 842 778 NA NA NA NA NA NA NA 27370 FUN_034116 1626 3545 1869 1510 1289 ptg000024l:5055482-5060589 Q8BJ56 4.56e-24 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 27371 FUN_034116 1626 3545 1869 1510 1289 ptg000024l:5055482-5060589 Q8BJ56 1.24e-22 Patatin-like phospholipase domain-containing protein 2 (EC 3.1.1.3) (Adipose triglyceride lipase) (Calcium-independent phospholipase A2-zeta) (iPLA2-zeta) (EC 3.1.1.4) (Desnutrin) Mus musculus (Mouse) cellular lipid catabolic process [GO:0044242]; diacylglycerol biosynthetic process [GO:0006651]; lipid droplet disassembly [GO:1905691]; lipid droplet organization [GO:0034389]; lipid homeostasis [GO:0055088]; lipid storage [GO:0019915]; negative regulation of sequestering of triglyceride [GO:0010891]; positive regulation of triglyceride catabolic process [GO:0010898]; triglyceride catabolic process [GO:0019433] GO:0004623; GO:0004806; GO:0005654; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0006651; GO:0010891; GO:0010898; GO:0016020; GO:0016411; GO:0019433; GO:0019915; GO:0034389; GO:0044242; GO:0050253; GO:0051264; GO:0051265; GO:0055088; GO:1905691 27372 FUN_034119 0 0 12 0 0 NA NA NA NA NA NA NA 27373 FUN_034118 942 1392 737 1324 860 NA NA NA NA NA NA NA 27374 FUN_022495 201 45 196 175 497 NA NA NA NA NA NA NA 27375 FUN_013991 0 0 0 12 59 NA NA NA NA NA NA NA 27376 FUN_013314 2006 949 774 1468 1370 NA NA NA NA NA NA NA 27377 FUN_043429 132 421 154 179 97 ptg000047l:8419904-8429250 G5EDE1 7.41e-59 Zinc finger protein GFI1 homolog pag-3 (Pattern of reporter gene expression abnormal protein 3) (Transcription factor pag-3) Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast fate specification [GO:0014018]; regulation of backward locomotion [GO:0043058]; regulation of forward locomotion [GO:0043059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001222; GO:0001227; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0014018; GO:0030424; GO:0043058; GO:0043059; GO:0043066; GO:0043204; GO:0045664; GO:0046676; GO:0046872; GO:0046929 27378 FUN_043428 386 119 100 229 193 ptg000047l:8403834-8406273 O42409 4.46e-91 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 27379 FUN_043428 386 119 100 229 193 ptg000047l:8403834-8406273 O42409 8.04e-21 Zinc finger protein Gfi-1b (Growth factor-independent protein 1B) Gallus gallus (Chicken) chromatin organization [GO:0006325]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001227; GO:0005654; GO:0006325; GO:0006357; GO:0046872 27380 FUN_043423 54 0 11 7 101 NA NA NA NA NA NA NA 27381 FUN_043422 1087 760 544 710 1057 NA NA NA NA NA NA NA 27382 FUN_043421 1614 963 782 1532 1676 ptg000047l:8334464-8356253 O70133 9.33e-26 ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (mHEL-5) (Nuclear DNA helicase II) (NDH II) (RNA helicase A) (RHA) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; DNA duplex unwinding [GO:0032508]; DNA-templated transcription termination [GO:0006353]; DNA-templated viral transcription [GO:0039695]; G-quadruplex DNA unwinding [GO:0044806]; global gene silencing by mRNA cleavage [GO:0098795]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mRNA transport [GO:0051028]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of inflammatory response [GO:0050729]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-18 production [GO:0032741]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of polysome binding [GO:1905698]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of RNA export from nucleus [GO:0046833]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of viral transcription [GO:0050434]; positive regulation of viral translation [GO:1904973]; protein localization to cytoplasmic stress granule [GO:1903608]; protein-containing complex assembly [GO:0065003]; pyroptosis [GO:0070269]; regulation of cytoplasmic translation [GO:2000765]; regulation of defense response to virus by host [GO:0050691]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501] GO:0000380; GO:0000978; GO:0000993; GO:0001069; GO:0003677; GO:0003678; GO:0003688; GO:0003690; GO:0003697; GO:0003712; GO:0003713; GO:0003723; GO:0003724; GO:0003725; GO:0003727; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005726; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005844; GO:0006353; GO:0006357; GO:0006954; GO:0007623; GO:0010501; GO:0015629; GO:0016442; GO:0016604; GO:0016887; GO:0017111; GO:0031490; GO:0032508; GO:0032727; GO:0032728; GO:0032741; GO:0032755; GO:0032760; GO:0032991; GO:0033679; GO:0034458; GO:0034605; GO:0035197; GO:0035613; GO:0036464; GO:0039695; GO:0042788; GO:0043138; GO:0044806; GO:0045087; GO:0045089; GO:0045142; GO:0045739; GO:0045740; GO:0045944; GO:0046833; GO:0046872; GO:0047429; GO:0048146; GO:0050434; GO:0050684; GO:0050691; GO:0050729; GO:0051028; GO:0051092; GO:0060760; GO:0061629; GO:0061676; GO:0065003; GO:0070063; GO:0070269; GO:0070578; GO:0070922; GO:0070934; GO:0070937; GO:0071356; GO:0071360; GO:0097165; GO:0098795; GO:1900152; GO:1903608; GO:1904973; GO:1905172; GO:1905538; GO:1905698; GO:1990518; GO:1990825; GO:1990841; GO:1990904; GO:2000373; GO:2000637; GO:2000765; GO:2000767 27383 FUN_043421 1614 963 782 1532 1676 ptg000047l:8334464-8356253 O70133 9.33e-26 ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (mHEL-5) (Nuclear DNA helicase II) (NDH II) (RNA helicase A) (RHA) Mus musculus (Mouse) alternative mRNA splicing, via spliceosome [GO:0000380]; cellular response to exogenous dsRNA [GO:0071360]; cellular response to heat [GO:0034605]; cellular response to tumor necrosis factor [GO:0071356]; circadian rhythm [GO:0007623]; CRD-mediated mRNA stabilization [GO:0070934]; DNA duplex unwinding [GO:0032508]; DNA-templated transcription termination [GO:0006353]; DNA-templated viral transcription [GO:0039695]; G-quadruplex DNA unwinding [GO:0044806]; global gene silencing by mRNA cleavage [GO:0098795]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; mRNA transport [GO:0051028]; negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900152]; positive regulation of cytoplasmic translation [GO:2000767]; positive regulation of DNA repair [GO:0045739]; positive regulation of DNA replication [GO:0045740]; positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [GO:2000373]; positive regulation of fibroblast proliferation [GO:0048146]; positive regulation of inflammatory response [GO:0050729]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-alpha production [GO:0032727]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of interleukin-18 production [GO:0032741]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of polysome binding [GO:1905698]; positive regulation of response to cytokine stimulus [GO:0060760]; positive regulation of RNA export from nucleus [GO:0046833]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of viral transcription [GO:0050434]; positive regulation of viral translation [GO:1904973]; protein localization to cytoplasmic stress granule [GO:1903608]; protein-containing complex assembly [GO:0065003]; pyroptosis [GO:0070269]; regulation of cytoplasmic translation [GO:2000765]; regulation of defense response to virus by host [GO:0050691]; regulation of mRNA processing [GO:0050684]; regulation of transcription by RNA polymerase II [GO:0006357]; RISC complex assembly [GO:0070922]; RNA secondary structure unwinding [GO:0010501] GO:0000380; GO:0000978; GO:0000993; GO:0001069; GO:0003677; GO:0003678; GO:0003688; GO:0003690; GO:0003697; GO:0003712; GO:0003713; GO:0003723; GO:0003724; GO:0003725; GO:0003727; GO:0003729; GO:0005524; GO:0005634; GO:0005654; GO:0005726; GO:0005730; GO:0005737; GO:0005813; GO:0005829; GO:0005844; GO:0006353; GO:0006357; GO:0006954; GO:0007623; GO:0010501; GO:0015629; GO:0016442; GO:0016604; GO:0016887; GO:0017111; GO:0031490; GO:0032508; GO:0032727; GO:0032728; GO:0032741; GO:0032755; GO:0032760; GO:0032991; GO:0033679; GO:0034458; GO:0034605; GO:0035197; GO:0035613; GO:0036464; GO:0039695; GO:0042788; GO:0043138; GO:0044806; GO:0045087; GO:0045089; GO:0045142; GO:0045739; GO:0045740; GO:0045944; GO:0046833; GO:0046872; GO:0047429; GO:0048146; GO:0050434; GO:0050684; GO:0050691; GO:0050729; GO:0051028; GO:0051092; GO:0060760; GO:0061629; GO:0061676; GO:0065003; GO:0070063; GO:0070269; GO:0070578; GO:0070922; GO:0070934; GO:0070937; GO:0071356; GO:0071360; GO:0097165; GO:0098795; GO:1900152; GO:1903608; GO:1904973; GO:1905172; GO:1905538; GO:1905698; GO:1990518; GO:1990825; GO:1990841; GO:1990904; GO:2000373; GO:2000637; GO:2000765; GO:2000767 27384 FUN_043420 23053 16249 13494 22280 20327 ptg000047l:8306672-8333405 P07751 9.71e-23 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005886; GO:0030036; GO:0030054; GO:0030864; GO:0042995; GO:0043034; GO:0051015; GO:0051693 27385 FUN_043420 23053 16249 13494 22280 20327 ptg000047l:8306672-8333405 P07751 9.71e-23 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005886; GO:0030036; GO:0030054; GO:0030864; GO:0042995; GO:0043034; GO:0051015; GO:0051693 27386 FUN_043420 23053 16249 13494 22280 20327 ptg000047l:8306672-8333405 P07751 9.71e-23 Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) Gallus gallus (Chicken) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693] GO:0005509; GO:0005516; GO:0005886; GO:0030036; GO:0030054; GO:0030864; GO:0042995; GO:0043034; GO:0051015; GO:0051693 27387 FUN_043427 1275 1066 867 1319 1273 NA NA NA NA NA NA NA 27388 FUN_043426 982 1378 883 881 914 NA NA NA NA NA NA NA 27389 FUN_043425 4980 4200 2662 4538 2665 NA NA NA NA NA NA NA 27390 FUN_043424 1945 2099 1070 1595 738 NA NA NA NA NA NA NA 27391 FUN_041375 0 0 14 28 35 NA NA NA NA NA NA NA 27392 FUN_041377 0 0 1 0 30 NA NA NA NA NA NA NA 27393 FUN_041376 110 7 46 12 58 ptg000035l:2847778-2848723 P61752 1.02e-25 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Pongo pygmaeus (Bornean orangutan) gastric acid secretion [GO:0001696]; positive regulation of vasoconstriction [GO:0045907] GO:0001696; GO:0004969; GO:0005886; GO:0045907 27394 FUN_041371 63 30 54 94 103 NA NA NA NA NA NA NA 27395 FUN_041370 298 300 319 550 386 NA NA NA NA NA NA NA 27396 FUN_041373 224 255 92 178 124 NA NA NA NA NA NA NA 27397 FUN_002244 0 0 0 0 12 NA NA NA NA NA NA NA 27398 FUN_002245 93 158 63 274 194 NA NA NA NA NA NA NA 27399 FUN_002247 0 0 5 31 19 NA NA NA NA NA NA NA 27400 FUN_002248 0 3 304 400 152 NA NA NA NA NA NA NA 27401 FUN_002249 0 0 0 40 0 NA NA NA NA NA NA NA 27402 FUN_007079 609 124 156 328 439 ptg000001l:20163207-20214785 Q0EEE2 6.3e-38 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 27403 FUN_007079 609 124 156 328 439 ptg000001l:20163207-20214785 Q0EEE2 5.31e-31 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 27404 FUN_022767 2726 1575 1048 1622 1797 ptg000016l:12804676-12816879 Q7ZX22 3.96e-21 GATOR complex protein WDR24 Xenopus laevis (African clawed frog) autophagy [GO:0006914]; positive regulation of TOR signaling [GO:0032008] GO:0005765; GO:0006914; GO:0032008 27405 FUN_022767 2726 1575 1048 1622 1797 ptg000016l:12804676-12816879 Q7ZX22 3.96e-21 GATOR complex protein WDR24 Xenopus laevis (African clawed frog) autophagy [GO:0006914]; positive regulation of TOR signaling [GO:0032008] GO:0005765; GO:0006914; GO:0032008 27406 FUN_043139 865 1276 700 1820 1722 ptg000047l:4484258-4488132 B8EIZ7 3.4e-76 NA NA NA NA 27407 FUN_011418 1424 1345 733 1465 1025 NA NA NA NA NA NA NA 27408 FUN_011417 435 226 134 178 244 NA NA NA NA NA NA NA 27409 FUN_043210 611 119 139 197 142 NA NA NA NA NA NA NA 27410 FUN_043211 1877 788 760 1106 1669 NA NA NA NA NA NA NA 27411 FUN_043212 1067 1326 1030 980 1516 NA NA NA NA NA NA NA 27412 FUN_033515 16 0 34 0 0 NA NA NA NA NA NA NA 27413 FUN_040422 341 457 240 148 162 NA NA NA NA NA NA NA 27414 FUN_040423 201 130 83 145 173 ptg000031l:8231153-8233354 Q8TBF8 6.17e-49 Protein FAM81A Homo sapiens (Human) NA GO:0098978; GO:0099092 27415 FUN_040420 148 61 129 379 263 NA NA NA NA NA NA NA 27416 FUN_007015 1756 1903 727 843 529 NA NA NA NA NA NA NA 27417 FUN_040426 209 62 160 215 183 ptg000031l:8276164-8277655 A6QQM4 9.61e-30 Zinc finger protein 474 Bos taurus (Bovine) NA GO:0046872 27418 FUN_040426 209 62 160 215 183 ptg000031l:8276164-8277655 A6QQM4 5e-21 Zinc finger protein 474 Bos taurus (Bovine) NA GO:0046872 27419 FUN_040427 819 408 412 598 807 NA NA NA NA NA NA NA 27420 FUN_040424 2111 1169 1069 1403 1130 ptg000031l:8236969-8264497 Q7YRF1 7.44e-31 AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain) Canis lupus familiaris (Dog) (Canis familiaris) anterograde axonal transport [GO:0008089]; anterograde synaptic vesicle transport [GO:0048490]; intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0005794; GO:0006886; GO:0008089; GO:0016192; GO:0030123; GO:0030131; GO:0030665; GO:0048490; GO:1904115 27421 FUN_040425 551 207 131 182 120 NA NA NA NA NA NA NA 27422 FUN_007012 108 161 43 141 227 ptg000001l:19291024-19296119 Q9CSH3 5.21e-25 Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44) Mus musculus (Mouse) CUT catabolic process [GO:0071034]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; rRNA processing [GO:0006364] GO:0000175; GO:0000176; GO:0000177; GO:0000178; GO:0003723; GO:0004519; GO:0005085; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006364; GO:0006396; GO:0006401; GO:0016075; GO:0071034 27423 FUN_040428 311 345 123 144 102 NA NA NA NA NA NA NA 27424 FUN_040429 148 149 267 112 171 NA NA NA NA NA NA NA 27425 FUN_011413 43 8 12 0 9 NA NA NA NA NA NA NA 27426 FUN_013313 0 9 13 6 39 ptg000008l:20829236-20833898 Q0V8L6 1.64e-116 Phospholipase D2 (PLD 2) (EC 3.1.4.4) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) Bos taurus (Bovine) inositol lipid-mediated signaling [GO:0048017]; phosphatidic acid biosynthetic process [GO:0006654]; phospholipid catabolic process [GO:0009395]; regulation of vesicle-mediated transport [GO:0060627] GO:0004630; GO:0005737; GO:0005886; GO:0006654; GO:0009395; GO:0035091; GO:0043231; GO:0048017; GO:0060627; GO:0070290 27427 FUN_007013 4174 2604 1923 3989 2879 NA NA NA NA NA NA NA 27428 FUN_043132 803 453 210 580 365 NA NA NA NA NA NA NA 27429 FUN_007010 652 1304 286 392 567 NA NA NA NA NA NA NA 27430 FUN_043135 634 148 141 612 438 NA NA NA NA NA NA NA 27431 FUN_043217 0 24 10 0 21 NA NA NA NA NA NA NA 27432 FUN_011414 116 5 96 44 86 NA NA NA NA NA NA NA 27433 FUN_042482 0 12 0 6 20 NA NA NA NA NA NA NA 27434 FUN_042483 10 13 6 8 33 NA NA NA NA NA NA NA 27435 FUN_042480 20 44 17 152 108 NA NA NA NA NA NA NA 27436 FUN_042481 14 12 9 7 28 NA NA NA NA NA NA NA 27437 FUN_042486 40 15 58 23 74 NA NA NA NA NA NA NA 27438 FUN_042487 38 21 50 42 1 NA NA NA NA NA NA NA 27439 FUN_042484 0 4 2 0 16 NA NA NA NA NA NA NA 27440 FUN_043219 287 107 106 208 370 ptg000047l:5527118-5535373 Q9QXW2 2.27e-23 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Mus musculus (Mouse) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 27441 FUN_042488 8 1 16 9 158 NA NA NA NA NA NA NA 27442 FUN_011416 9272 9346 7197 7334 4342 ptg000007l:9636809-9645872 Q5FVQ4 3.48e-25 Malectin Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; protein N-linked glycosylation [GO:0006487] GO:0005783; GO:0005975; GO:0006487; GO:0008250; GO:0016020; GO:0019899; GO:0030246 27443 FUN_002938 0 0 12 0 2 NA NA NA NA NA NA NA 27444 FUN_002930 814 389 5 431 117 NA NA NA NA NA NA NA 27445 FUN_002936 0 0 2 0 12 NA NA NA NA NA NA NA 27446 FUN_002934 0 0 0 0 16 NA NA NA NA NA NA NA 27447 FUN_002935 23 15 9 0 144 NA NA NA NA NA NA NA 27448 FUN_029805 0 0 35 0 90 NA NA NA NA NA NA NA 27449 FUN_029803 0 0 0 0 204 NA NA NA NA NA NA NA 27450 FUN_019069 0 0 14 15 88 NA NA NA NA NA NA NA 27451 FUN_003716 1332 1311 716 2157 1426 ntLink_8:14635278-14639071 Q91398 3.47e-66 Casein kinase II subunit beta (CK II beta) Danio rerio (Zebrafish) (Brachydanio rerio) regulation of protein serine/threonine phosphatase activity [GO:0080163]; Wnt signaling pathway [GO:0016055] GO:0005737; GO:0005956; GO:0016055; GO:0019887; GO:0046872; GO:0080163 27452 FUN_043996 0 0 9 0 0 NA NA NA NA NA NA NA 27453 FUN_032470 26 66 21 65 31 NA NA NA NA NA NA NA 27454 FUN_032471 21 51 4 47 36 NA NA NA NA NA NA NA 27455 FUN_043999 0 0 11 0 0 NA NA NA NA NA NA NA 27456 FUN_032474 108 833 4 1348 0 ptg000023l:32303484-32315978 Q8IUL8 5.29e-32 Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2] Homo sapiens (Human) NA GO:0005615; GO:0070062 27457 FUN_032475 0 0 0 19 0 NA NA NA NA NA NA NA 27458 FUN_032476 209 125 176 229 153 NA NA NA NA NA NA NA 27459 FUN_032477 1406 890 937 1263 1617 NA NA NA NA NA NA NA 27460 FUN_008479 2408 1965 1826 2084 1481 NA NA NA NA NA NA NA 27461 FUN_008478 167 110 75 81 180 NA NA NA NA NA NA NA 27462 FUN_008471 108 74 62 85 208 NA NA NA NA NA NA NA 27463 FUN_008470 115 94 33 111 102 ptg000002l:11989186-11990476 Q7TN88 2.23e-39 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 27464 FUN_008473 1604 892 629 1153 755 NA NA NA NA NA NA NA 27465 FUN_008472 0 0 0 12 12 NA NA NA NA NA NA NA 27466 FUN_008475 19 0 0 34 43 NA NA NA NA NA NA NA 27467 FUN_008474 231 108 142 393 127 ptg000002l:12013855-12025885 Q7TN88 4.65e-48 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 27468 FUN_008474 231 108 142 393 127 ptg000002l:12013855-12025885 Q7TN88 9.22e-21 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 27469 FUN_008477 0 72 66 14 19 NA NA NA NA NA NA NA 27470 FUN_008476 0 0 9 12 39 NA NA NA NA NA NA NA 27471 FUN_033662 1 2 34 5 164 NA NA NA NA NA NA NA 27472 FUN_000268 388 236 325 1097 234 NA NA NA NA NA NA NA 27473 FUN_001334 3383 2745 967 924 1869 NA NA NA NA NA NA NA 27474 FUN_000264 7196 7488 4149 6699 5205 ntLink_6:884987-886628 O35182 7.63e-34 Mothers against decapentaplegic homolog 6 (MAD homolog 6) (Mothers against DPP homolog 6) (Mad homolog 7) (SMAD family member 6) (SMAD 6) (Smad6) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; BMP signaling pathway [GO:0030509]; cardiac vascular smooth muscle cell development [GO:0060948]; cell differentiation [GO:0030154]; cell-substrate adhesion [GO:0031589]; coronary vasculature development [GO:0060976]; coronary vasculature morphogenesis [GO:0060977]; fat cell differentiation [GO:0045444]; heart valve development [GO:0003170]; immune response [GO:0006955]; mitral valve morphogenesis [GO:0003183]; negative regulation of apoptotic process [GO:0043066]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of vasoconstriction [GO:0045907]; pulmonary valve morphogenesis [GO:0003184]; response to estrogen [GO:0043627]; response to laminar fluid shear stress [GO:0034616]; response to lipopolysaccharide [GO:0032496]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; vasoconstriction [GO:0042310]; ventricular septum development [GO:0003281]; zygotic specification of dorsal/ventral axis [GO:0007352] GO:0000976; GO:0001657; GO:0003148; GO:0003170; GO:0003180; GO:0003183; GO:0003184; GO:0003281; GO:0003682; GO:0005634; GO:0005654; GO:0005794; GO:0005829; GO:0006955; GO:0007179; GO:0007352; GO:0008285; GO:0009653; GO:0010991; GO:0016604; GO:0030154; GO:0030279; GO:0030509; GO:0030512; GO:0030514; GO:0031589; GO:0031625; GO:0032496; GO:0032991; GO:0034616; GO:0034713; GO:0035904; GO:0042310; GO:0042802; GO:0043066; GO:0043627; GO:0045444; GO:0045668; GO:0045907; GO:0046872; GO:0060394; GO:0060395; GO:0060948; GO:0060976; GO:0060977; GO:0070410; GO:0070411; GO:0070412; GO:0070698; GO:0071144; GO:0140416; GO:1902895 27475 FUN_000265 2679 2168 1647 1994 2413 ntLink_6:893738-900351 O70436 4.86e-121 Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (SMAD family member 2) (SMAD 2) (Smad2) Rattus norvegicus (Rat) activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; aortic valve morphogenesis [GO:0003180]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; common-partner SMAD protein phosphorylation [GO:0007182]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endocardial cushion morphogenesis [GO:0003203]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; gastrulation [GO:0007369]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; insulin secretion [GO:0030073]; intracellular signal transduction [GO:0035556]; lung development [GO:0030324]; mesoderm formation [GO:0001707]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; nodal signaling pathway [GO:0038092]; organ growth [GO:0035265]; pancreas development [GO:0031016]; paraxial mesoderm morphogenesis [GO:0048340]; pattern specification process [GO:0007389]; pericardium development [GO:0060039]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; pulmonary valve morphogenesis [GO:0003184]; regulation of binding [GO:0051098]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to glucose [GO:0009749]; secondary palate development [GO:0062009]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]; zygotic specification of dorsal/ventral axis [GO:0007352] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001657; GO:0001701; GO:0001706; GO:0001707; GO:0003180; GO:0003184; GO:0003203; GO:0003677; GO:0003682; GO:0003690; GO:0003700; GO:0005160; GO:0005634; GO:0005667; GO:0005737; GO:0006468; GO:0007179; GO:0007182; GO:0007183; GO:0007352; GO:0007369; GO:0007389; GO:0007492; GO:0007507; GO:0008285; GO:0009653; GO:0009749; GO:0009791; GO:0009880; GO:0009952; GO:0010628; GO:0010629; GO:0010718; GO:0017015; GO:0019902; GO:0023019; GO:0030073; GO:0030154; GO:0030324; GO:0030325; GO:0030513; GO:0031016; GO:0031625; GO:0032444; GO:0032924; GO:0032991; GO:0034713; GO:0035265; GO:0035556; GO:0038092; GO:0042060; GO:0042802; GO:0045165; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0048156; GO:0048340; GO:0048589; GO:0048617; GO:0048701; GO:0051098; GO:0060039; GO:0060395; GO:0061629; GO:0062009; GO:0070410; GO:0070411; GO:0070412; GO:0070723; GO:0071141; GO:0071142; GO:0071144; GO:0097718; GO:0140297; GO:1900224 27476 FUN_000265 2679 2168 1647 1994 2413 ntLink_6:893738-900351 O70436 6.06e-41 Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (SMAD family member 2) (SMAD 2) (Smad2) Rattus norvegicus (Rat) activin receptor signaling pathway [GO:0032924]; adrenal gland development [GO:0030325]; anatomical structure morphogenesis [GO:0009653]; anterior/posterior pattern specification [GO:0009952]; aortic valve morphogenesis [GO:0003180]; cell differentiation [GO:0030154]; cell fate commitment [GO:0045165]; common-partner SMAD protein phosphorylation [GO:0007182]; developmental growth [GO:0048589]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic foregut morphogenesis [GO:0048617]; embryonic pattern specification [GO:0009880]; endocardial cushion morphogenesis [GO:0003203]; endoderm development [GO:0007492]; endoderm formation [GO:0001706]; gastrulation [GO:0007369]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; insulin secretion [GO:0030073]; intracellular signal transduction [GO:0035556]; lung development [GO:0030324]; mesoderm formation [GO:0001707]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; nodal signaling pathway [GO:0038092]; organ growth [GO:0035265]; pancreas development [GO:0031016]; paraxial mesoderm morphogenesis [GO:0048340]; pattern specification process [GO:0007389]; pericardium development [GO:0060039]; positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of gene expression [GO:0010628]; positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [GO:1900224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; pulmonary valve morphogenesis [GO:0003184]; regulation of binding [GO:0051098]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; response to cholesterol [GO:0070723]; response to glucose [GO:0009749]; secondary palate development [GO:0062009]; signal transduction involved in regulation of gene expression [GO:0023019]; SMAD protein complex assembly [GO:0007183]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ureteric bud development [GO:0001657]; wound healing [GO:0042060]; zygotic specification of dorsal/ventral axis [GO:0007352] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0001657; GO:0001701; GO:0001706; GO:0001707; GO:0003180; GO:0003184; GO:0003203; GO:0003677; GO:0003682; GO:0003690; GO:0003700; GO:0005160; GO:0005634; GO:0005667; GO:0005737; GO:0006468; GO:0007179; GO:0007182; GO:0007183; GO:0007352; GO:0007369; GO:0007389; GO:0007492; GO:0007507; GO:0008285; GO:0009653; GO:0009749; GO:0009791; GO:0009880; GO:0009952; GO:0010628; GO:0010629; GO:0010718; GO:0017015; GO:0019902; GO:0023019; GO:0030073; GO:0030154; GO:0030324; GO:0030325; GO:0030513; GO:0031016; GO:0031625; GO:0032444; GO:0032924; GO:0032991; GO:0034713; GO:0035265; GO:0035556; GO:0038092; GO:0042060; GO:0042802; GO:0045165; GO:0045892; GO:0045893; GO:0045944; GO:0046332; GO:0046872; GO:0048156; GO:0048340; GO:0048589; GO:0048617; GO:0048701; GO:0051098; GO:0060039; GO:0060395; GO:0061629; GO:0062009; GO:0070410; GO:0070411; GO:0070412; GO:0070723; GO:0071141; GO:0071142; GO:0071144; GO:0097718; GO:0140297; GO:1900224 27477 FUN_000266 126 214 176 161 115 NA NA NA NA NA NA NA 27478 FUN_000267 3348 3008 1445 3202 2701 NA NA NA NA NA NA NA 27479 FUN_000260 2624 3240 1706 2348 1593 NA NA NA NA NA NA NA 27480 FUN_000261 600 146 567 622 463 NA NA NA NA NA NA NA 27481 FUN_000262 426 132 228 285 266 NA NA NA NA NA NA NA 27482 FUN_000263 1921 1055 868 1091 1016 NA NA NA NA NA NA NA 27483 FUN_001336 407 164 214 329 311 ntLink_6:11236103-11241771 Q5R6B8 1.94e-26 Sodium/hydrogen exchanger 9B2 (Na(+)/H(+) exchanger NHA2) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Sodium/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) clathrin-dependent endocytosis [GO:0072583]; flagellated sperm motility [GO:0030317]; positive regulation of osteoclast development [GO:2001206]; regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0061178] GO:0005886; GO:0010008; GO:0010348; GO:0015385; GO:0016323; GO:0030317; GO:0030672; GO:0031966; GO:0042802; GO:0061178; GO:0072583; GO:0097228; GO:2001206 27484 FUN_033666 3294 4180 2158 5088 9655 ptg000024l:105536-106214 Q5XIU9 1.78e-27 Membrane-associated progesterone receptor component 2 Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; heme transport [GO:0015886] GO:0005496; GO:0005635; GO:0005783; GO:0012505; GO:0015232; GO:0015886; GO:0016020; GO:0020037; GO:0060612 27485 FUN_001330 2939 1623 1181 2437 2369 ntLink_6:11188731-11193508 Q9Z0K8 6.96e-118 Pantetheinase (EC 3.5.1.92) (Pantetheine hydrolase) (Vascular non-inflammatory molecule 1) (Vanin-1) Mus musculus (Mouse) acute inflammatory response [GO:0002526]; cell-cell adhesion [GO:0098609]; chronic inflammatory response [GO:0002544]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; pantothenate metabolic process [GO:0015939]; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902177]; positive regulation of T cell differentiation in thymus [GO:0033089] GO:0002526; GO:0002544; GO:0005886; GO:0006954; GO:0015939; GO:0016020; GO:0017159; GO:0033089; GO:0034235; GO:0045087; GO:0098609; GO:1902177 27486 FUN_033664 11 17 14 17 13 NA NA NA NA NA NA NA 27487 FUN_016776 642 679 296 549 351 ptg000011l:7352657-7360869 Q96AY4 3.67e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27488 FUN_016776 642 679 296 549 351 ptg000011l:7352657-7360869 Q96AY4 3.54e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27489 FUN_016776 642 679 296 549 351 ptg000011l:7352657-7360869 Q96AY4 2.34e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27490 FUN_016776 642 679 296 549 351 ptg000011l:7352657-7360869 Q96AY4 1.02e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27491 FUN_016776 642 679 296 549 351 ptg000011l:7352657-7360869 Q96AY4 8.05e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27492 FUN_001332 764 499 318 608 738 ntLink_6:11199053-11204901 Q9Y3Q0 7.83e-89 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Homo sapiens (Human) proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008236; GO:0008239; GO:0016020; GO:0016805; GO:0046872 27493 FUN_014532 17 9 17 0 22 NA NA NA NA NA NA NA 27494 FUN_029113 2479 10511 1404 1769 5629 NA NA NA NA NA NA NA 27495 FUN_029112 4501 3709 2975 4534 2759 NA NA NA NA NA NA NA 27496 FUN_029111 402 785 169 360 833 NA NA NA NA NA NA NA 27497 FUN_029110 1778 2013 882 1280 633 NA NA NA NA NA NA NA 27498 FUN_029117 3653 1618 1775 3035 2445 NA NA NA NA NA NA NA 27499 FUN_029116 0 6 0 0 14 NA NA NA NA NA NA NA 27500 FUN_029115 217 103 69 333 168 NA NA NA NA NA NA NA 27501 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 9.6e-153 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27502 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 3e-143 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27503 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 2.83e-131 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27504 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 9.45e-129 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27505 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 1.85e-127 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27506 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 2.18e-118 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27507 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 2.1e-114 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27508 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 3.34e-114 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27509 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 3.42e-112 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27510 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 2.05e-47 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27511 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 8.09e-44 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27512 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 1.44e-23 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27513 FUN_029114 30 47 14 123 178 ptg000022l:8354323-8360911 P18294 5.75e-23 Creatine kinase, flagellar (EC 2.7.3.2) Strongylocentrotus purpuratus (Purple sea urchin) cell projection organization [GO:0030030]; phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005737; GO:0005856; GO:0016301; GO:0016310; GO:0030030; GO:0031514; GO:0046314 27514 FUN_029119 1225 536 780 935 563 ptg000022l:8397664-8399047 C4R7Z3 3.33e-140 Sphingolipid C9-methyltransferase (C-9-MT) (EC 2.1.1.317) Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) methylation [GO:0032259]; sphingolipid metabolic process [GO:0006665] GO:0006665; GO:0008168; GO:0016020; GO:0032259 27515 FUN_029118 34 0 31 3 111 NA NA NA NA NA NA NA 27516 FUN_033709 3746 1584 1210 3149 1643 NA NA NA NA NA NA NA 27517 FUN_033708 55935 60566 30299 48163 30054 NA NA NA NA NA NA NA 27518 FUN_033701 985 886 615 1243 1067 NA NA NA NA NA NA NA 27519 FUN_033700 1408 721 690 1362 909 NA NA NA NA NA NA NA 27520 FUN_033703 1309 794 718 741 462 NA NA NA NA NA NA NA 27521 FUN_033702 1 2 1 6 2 NA NA NA NA NA NA NA 27522 FUN_033705 78 23 58 32 46 NA NA NA NA NA NA NA 27523 FUN_033704 11 37 24 48 120 ptg000024l:550194-552440 A0A2B4RNI3 0 NA NA NA NA 27524 FUN_033707 4638 2812 2194 4539 2953 NA NA NA NA NA NA NA 27525 FUN_033706 466 396 242 234 298 NA NA NA NA NA NA NA 27526 FUN_039346 164 7 0 175 0 ptg000029c:253106-267380 F6R2G2 1.86e-21 NLR family CARD domain-containing protein 4 (Ice protease-activating factor) (Ipaf) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0005829; GO:0006915; GO:0006954; GO:0042981; GO:0045087 27527 FUN_039345 13 0 0 0 0 ptg000029c:252185-253063 Q80TC5 3.26e-25 Pogo transposable element with KRAB domain Mus musculus (Mouse) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 27528 FUN_039344 90 423 35 32 58 NA NA NA NA NA NA NA 27529 FUN_039342 112 135 57 40 73 ptg000029c:201753-210504 B9IUR6 5.14e-44 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain Q1) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 27530 FUN_039341 19 2 0 7 22 NA NA NA NA NA NA NA 27531 FUN_039348 29 0 0 0 0 NA NA NA NA NA NA NA 27532 FUN_002678 769 264 133 97 108 NA NA NA NA NA NA NA 27533 FUN_010488 6 0 3 3 0 NA NA NA NA NA NA NA 27534 FUN_010483 0 0 0 0 9 NA NA NA NA NA NA NA 27535 FUN_010485 0 0 0 20 0 NA NA NA NA NA NA NA 27536 FUN_010484 336 293 165 179 884 NA NA NA NA NA NA NA 27537 FUN_010487 14 0 2 2 0 NA NA NA NA NA NA NA 27538 FUN_012393 127 84 92 255 86 NA NA NA NA NA NA NA 27539 FUN_012390 2997 2298 1849 4015 1516 NA NA NA NA NA NA NA 27540 FUN_012396 58 246 70 207 138 NA NA NA NA NA NA NA 27541 FUN_012395 28 0 12 95 19 NA NA NA NA NA NA NA 27542 FUN_012394 640 429 632 1122 351 NA NA NA NA NA NA NA 27543 FUN_012399 26 0 14 31 79 NA NA NA NA NA NA NA 27544 FUN_012398 49 48 17 45 128 NA NA NA NA NA NA NA 27545 FUN_010733 12643 12870 6875 12868 8037 ptg000007l:2176473-2183037 A7SA47 3.91e-24 Eukaryotic translation initiation factor 3 subunit H (eIF3h) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0003743; GO:0005852; GO:0008237; GO:0016282; GO:0033290; GO:0042788 27546 FUN_010733 12643 12870 6875 12868 8037 ptg000007l:2176473-2183037 A7SA47 7.02e-22 Eukaryotic translation initiation factor 3 subunit H (eIF3h) Nematostella vectensis (Starlet sea anemone) formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0003743; GO:0005852; GO:0008237; GO:0016282; GO:0033290; GO:0042788 27547 FUN_010732 420 178 139 338 332 ptg000007l:2172314-2174328 P29083 4.93e-46 General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha) Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367]; transcription open complex formation at RNA polymerase II promoter [GO:0001113] GO:0001113; GO:0005634; GO:0005654; GO:0005669; GO:0005673; GO:0005829; GO:0006366; GO:0006367; GO:0016251; GO:0046872; GO:0060090; GO:0097550 27548 FUN_010731 18 11 8 33 70 NA NA NA NA NA NA NA 27549 FUN_010730 0 54 30 0 35 NA NA NA NA NA NA NA 27550 FUN_010736 23015 17339 10253 23029 18678 NA NA NA NA NA NA NA 27551 FUN_010735 16226 10809 4822 13241 6128 ptg000007l:2183362-2186966 Q9V9J3 6.78e-177 Tyrosine-protein kinase Src42A (EC 2.7.10.2) (Tyrosine-protein kinase Src41) (Dsrc41) Drosophila melanogaster (Fruit fly) actin filament bundle assembly [GO:0051017]; adherens junction organization [GO:0034332]; apoptotic cell clearance [GO:0043277]; axon guidance [GO:0007411]; cell differentiation [GO:0030154]; cell migration [GO:0016477]; compound eye development [GO:0048749]; defense response to bacterium [GO:0042742]; dorsal closure [GO:0007391]; dorsal closure, spreading of leading edge cells [GO:0007395]; epithelial cell-cell adhesion [GO:0090136]; hydrogen peroxide mediated signaling pathway [GO:0071588]; imaginal disc fusion, thorax closure [GO:0046529]; imaginal disc-derived wing morphogenesis [GO:0007476]; innate immune response [GO:0045087]; intestinal stem cell homeostasis [GO:0036335]; negative regulation of epidermal growth factor receptor signaling pathway [GO:0042059]; negative regulation of synaptic assembly at neuromuscular junction [GO:0045886]; open tracheal system development [GO:0007424]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of epidermal growth factor receptor signaling pathway [GO:0045742]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of sevenless signaling pathway [GO:0045874]; protein phosphorylation [GO:0006468]; regulation of synaptic plasticity [GO:0048167]; salivary gland morphogenesis [GO:0007435]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004715; GO:0005102; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006468; GO:0007169; GO:0007391; GO:0007395; GO:0007411; GO:0007424; GO:0007435; GO:0007476; GO:0016477; GO:0018108; GO:0030154; GO:0031234; GO:0034332; GO:0036335; GO:0042059; GO:0042742; GO:0043277; GO:0045087; GO:0045742; GO:0045874; GO:0045886; GO:0046529; GO:0048167; GO:0048749; GO:0051017; GO:0070374; GO:0071588; GO:0090136; GO:0106016 27552 FUN_010734 1023 609 275 643 238 NA NA NA NA NA NA NA 27553 FUN_010739 69 78 15 36 50 NA NA NA NA NA NA NA 27554 FUN_010738 318 228 47 204 169 NA NA NA NA NA NA NA 27555 FUN_012647 0 0 0 0 14 NA NA NA NA NA NA NA 27556 FUN_012646 367 248 251 614 203 NA NA NA NA NA NA NA 27557 FUN_012640 922 463 419 594 537 NA NA NA NA NA NA NA 27558 FUN_012643 903 718 376 342 478 NA NA NA NA NA NA NA 27559 FUN_012649 223 110 30 255 63 NA NA NA NA NA NA NA 27560 FUN_012648 1182 584 534 882 628 ptg000008l:10915596-10921082 O43246 7.41e-60 Cationic amino acid transporter 4 (CAT-4) (CAT4) (Solute carrier family 7 member 4) Homo sapiens (Human) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0015171; GO:0015174; GO:0016020 27561 FUN_003505 32 0 29 34 75 NA NA NA NA NA NA NA 27562 FUN_030311 4 0 5 0 22 ptg000023l:10584212-10584975 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27563 FUN_038919 1074 831 460 660 600 ptg000027l:12833503-12844681 Q55DL2 1.39e-45 Histidine protein methyltransferase 1 homolog (EC 2.1.1.85) (Protein METTL18 homolog) Dictyostelium discoideum (Social amoeba) peptidyl-histidine methylation, to form tele-methylhistidine [GO:0042038]; peptidyl-lysine monomethylation [GO:0018026] GO:0005730; GO:0005829; GO:0018026; GO:0018064; GO:0042038 27564 FUN_038918 4933 3446 2214 3915 2226 NA NA NA NA NA NA NA 27565 FUN_038915 4400 2370 2887 4911 3324 NA NA NA NA NA NA NA 27566 FUN_038914 112 146 48 116 185 NA NA NA NA NA NA NA 27567 FUN_038917 1662 1812 1153 1589 1213 NA NA NA NA NA NA NA 27568 FUN_038916 2266 1295 1353 1828 1955 ptg000027l:12806944-12821826 Q9W0T1 9.27e-71 Nucleosome-remodeling factor subunit NURF301 (Enhancer of bithorax) (Nucleosome-remodeling factor 215 kDa subunit) (NURF-215) Drosophila melanogaster (Fruit fly) chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; hemopoiesis [GO:0030097]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of innate immune response [GO:0045824]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; nucleosome organization [GO:0034728]; positive regulation of DNA-templated transcription [GO:0045893]; pupariation [GO:0035073]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid differentiation [GO:0048515] GO:0000978; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0010468; GO:0016589; GO:0016922; GO:0030097; GO:0034728; GO:0035064; GO:0035073; GO:0035076; GO:0045824; GO:0045892; GO:0045893; GO:0046426; GO:0046872; GO:0048515; GO:0070577 27569 FUN_038916 2266 1295 1353 1828 1955 ptg000027l:12806944-12821826 Q9W0T1 7.85e-25 Nucleosome-remodeling factor subunit NURF301 (Enhancer of bithorax) (Nucleosome-remodeling factor 215 kDa subunit) (NURF-215) Drosophila melanogaster (Fruit fly) chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; hemopoiesis [GO:0030097]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of innate immune response [GO:0045824]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; nucleosome organization [GO:0034728]; positive regulation of DNA-templated transcription [GO:0045893]; pupariation [GO:0035073]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid differentiation [GO:0048515] GO:0000978; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0010468; GO:0016589; GO:0016922; GO:0030097; GO:0034728; GO:0035064; GO:0035073; GO:0035076; GO:0045824; GO:0045892; GO:0045893; GO:0046426; GO:0046872; GO:0048515; GO:0070577 27570 FUN_038916 2266 1295 1353 1828 1955 ptg000027l:12806944-12821826 Q9W0T1 7.85e-25 Nucleosome-remodeling factor subunit NURF301 (Enhancer of bithorax) (Nucleosome-remodeling factor 215 kDa subunit) (NURF-215) Drosophila melanogaster (Fruit fly) chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; hemopoiesis [GO:0030097]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of innate immune response [GO:0045824]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; nucleosome organization [GO:0034728]; positive regulation of DNA-templated transcription [GO:0045893]; pupariation [GO:0035073]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid differentiation [GO:0048515] GO:0000978; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0010468; GO:0016589; GO:0016922; GO:0030097; GO:0034728; GO:0035064; GO:0035073; GO:0035076; GO:0045824; GO:0045892; GO:0045893; GO:0046426; GO:0046872; GO:0048515; GO:0070577 27571 FUN_038916 2266 1295 1353 1828 1955 ptg000027l:12806944-12821826 Q9W0T1 2.39e-22 Nucleosome-remodeling factor subunit NURF301 (Enhancer of bithorax) (Nucleosome-remodeling factor 215 kDa subunit) (NURF-215) Drosophila melanogaster (Fruit fly) chromatin remodeling [GO:0006338]; ecdysone receptor-mediated signaling pathway [GO:0035076]; hemopoiesis [GO:0030097]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of innate immune response [GO:0045824]; negative regulation of receptor signaling pathway via JAK-STAT [GO:0046426]; nucleosome organization [GO:0034728]; positive regulation of DNA-templated transcription [GO:0045893]; pupariation [GO:0035073]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; spermatid differentiation [GO:0048515] GO:0000978; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0010468; GO:0016589; GO:0016922; GO:0030097; GO:0034728; GO:0035064; GO:0035073; GO:0035076; GO:0045824; GO:0045892; GO:0045893; GO:0046426; GO:0046872; GO:0048515; GO:0070577 27572 FUN_038911 0 109 25 60 0 NA NA NA NA NA NA NA 27573 FUN_038913 89 34 43 60 32 ptg000027l:12757050-12757842 Q17QQ2 4.08e-39 Thiopurine S-methyltransferase (EC 2.1.1.67) (Thiopurine methyltransferase) Bos taurus (Bovine) methylation [GO:0032259]; xenobiotic metabolic process [GO:0006805] GO:0005737; GO:0006805; GO:0008119; GO:0032259; GO:1904047 27574 FUN_038912 35 14 27 34 12 NA NA NA NA NA NA NA 27575 FUN_014496 3169 2790 2193 3141 2962 NA NA NA NA NA NA NA 27576 FUN_014497 7229 6678 4676 6348 4132 NA NA NA NA NA NA NA 27577 FUN_014494 1305 659 424 857 902 ptg000009l:636381-643033 Q9NV66 4.92e-29 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0010181; GO:0031591; GO:0046872; GO:0051539; GO:0102521 27578 FUN_014494 1305 659 424 857 902 ptg000009l:636381-643033 Q9NV66 1.33e-22 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0010181; GO:0031591; GO:0046872; GO:0051539; GO:0102521 27579 FUN_014494 1305 659 424 857 902 ptg000009l:636381-643033 Q9NV66 1.33e-22 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0010181; GO:0031591; GO:0046872; GO:0051539; GO:0102521 27580 FUN_014495 3141 3774 1966 3033 2374 NA NA NA NA NA NA NA 27581 FUN_014492 825 767 899 672 509 NA NA NA NA NA NA NA 27582 FUN_014493 467 92 176 195 184 NA NA NA NA NA NA NA 27583 FUN_014490 602 591 589 611 544 NA NA NA NA NA NA NA 27584 FUN_014491 1017 705 701 737 795 ptg000009l:628927-630866 Q3SWZ6 8.96e-34 Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein homolog) Bos taurus (Bovine) bone marrow development [GO:0048539]; bone mineralization [GO:0030282]; cytosolic ribosome assembly [GO:0042256]; hematopoietic progenitor cell differentiation [GO:0002244]; inner cell mass cell proliferation [GO:0001833]; leukocyte chemotaxis [GO:0030595]; mitotic spindle organization [GO:0007052]; rRNA processing [GO:0006364] GO:0000922; GO:0001833; GO:0002244; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0007052; GO:0008017; GO:0019843; GO:0030282; GO:0030595; GO:0042256; GO:0043022; GO:0048539 27585 FUN_014491 1017 705 701 737 795 ptg000009l:628927-630866 Q3SWZ6 6.16e-28 Ribosome maturation protein SBDS (Shwachman-Bodian-Diamond syndrome protein homolog) Bos taurus (Bovine) bone marrow development [GO:0048539]; bone mineralization [GO:0030282]; cytosolic ribosome assembly [GO:0042256]; hematopoietic progenitor cell differentiation [GO:0002244]; inner cell mass cell proliferation [GO:0001833]; leukocyte chemotaxis [GO:0030595]; mitotic spindle organization [GO:0007052]; rRNA processing [GO:0006364] GO:0000922; GO:0001833; GO:0002244; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006364; GO:0007052; GO:0008017; GO:0019843; GO:0030282; GO:0030595; GO:0042256; GO:0043022; GO:0048539 27586 FUN_014498 1088 1011 561 1213 1427 NA NA NA NA NA NA NA 27587 FUN_014499 805 608 284 676 397 ptg000009l:672486-674343 Q6DE37 1.46e-52 Glucoside xylosyltransferase 2 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 4) Xenopus laevis (African clawed frog) O-glycan processing [GO:0016266] GO:0016020; GO:0016266; GO:0035252; GO:0140563 27588 FUN_014499 805 608 284 676 397 ptg000009l:672486-674343 Q6DE37 1.46e-52 Glucoside xylosyltransferase 2 (EC 2.4.2.42) (Glycosyltransferase 8 domain-containing protein 4) Xenopus laevis (African clawed frog) O-glycan processing [GO:0016266] GO:0016020; GO:0016266; GO:0035252; GO:0140563 27589 FUN_014728 972 1183 472 651 739 NA NA NA NA NA NA NA 27590 FUN_014729 6514 13487 5098 8537 13293 NA NA NA NA NA NA NA 27591 FUN_013118 57 2 0 43 3 NA NA NA NA NA NA NA 27592 FUN_013119 8 0 17 0 101 NA NA NA NA NA NA NA 27593 FUN_013112 0 0 11 0 0 NA NA NA NA NA NA NA 27594 FUN_014721 0 0 1 0 83 NA NA NA NA NA NA NA 27595 FUN_014722 372 286 127 242 263 NA NA NA NA NA NA NA 27596 FUN_014723 608 484 327 311 419 NA NA NA NA NA NA NA 27597 FUN_014724 1964 913 1171 2273 1604 NA NA NA NA NA NA NA 27598 FUN_014725 1438 917 766 1111 768 NA NA NA NA NA NA NA 27599 FUN_014726 111 74 62 103 63 NA NA NA NA NA NA NA 27600 FUN_014727 1435 1371 954 1176 800 NA NA NA NA NA NA NA 27601 FUN_009793 4 30 0 0 13 NA NA NA NA NA NA NA 27602 FUN_009792 0 31 0 0 0 NA NA NA NA NA NA NA 27603 FUN_009791 12 0 0 0 0 NA NA NA NA NA NA NA 27604 FUN_009790 31 26 0 0 0 NA NA NA NA NA NA NA 27605 FUN_009797 132 66 8 45 139 NA NA NA NA NA NA NA 27606 FUN_009796 71 605 0 79 3 NA NA NA NA NA NA NA 27607 FUN_009795 3303 6126 29 1903 120 NA NA NA NA NA NA NA 27608 FUN_009794 652 163 11 0 0 NA NA NA NA NA NA NA 27609 FUN_009799 0 0 3 8 11 NA NA NA NA NA NA NA 27610 FUN_009798 264 6 0 44 25 NA NA NA NA NA NA NA 27611 FUN_009245 67 61 12 30 16 ptg000004l:4468099-4471461 Q96AY4 1.81e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27612 FUN_009245 67 61 12 30 16 ptg000004l:4468099-4471461 Q96AY4 1.81e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27613 FUN_009245 67 61 12 30 16 ptg000004l:4468099-4471461 Q96AY4 3.17e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27614 FUN_009245 67 61 12 30 16 ptg000004l:4468099-4471461 Q96AY4 1.1e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27615 FUN_009245 67 61 12 30 16 ptg000004l:4468099-4471461 Q96AY4 2.16e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27616 FUN_009245 67 61 12 30 16 ptg000004l:4468099-4471461 Q96AY4 2.18e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27617 FUN_009244 10 78 95 0 0 NA NA NA NA NA NA NA 27618 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 6.69e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27619 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 6.69e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27620 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 7.44e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27621 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 1.11e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27622 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 1.13e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27623 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 8.49e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27624 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 3.53e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27625 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 8.85e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27626 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 1.24e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27627 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 2.26e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27628 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 4.55e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27629 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 4.37e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27630 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 3.53e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27631 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 5.92e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27632 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 1.55e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27633 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 1.06e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27634 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 5.78e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27635 FUN_009247 25 53 0 21 21 ptg000004l:4517182-4521090 Q96AY4 3.89e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27636 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 5.77e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27637 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 4.19e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27638 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 1.09e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27639 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 7.4e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27640 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 2.1e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27641 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 9.72e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27642 FUN_009246 62 245 93 60 49 ptg000004l:4492922-4504572 Q96AY4 1.15e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27643 FUN_009241 16 16 0 0 0 NA NA NA NA NA NA NA 27644 FUN_009240 52 84 37 15 28 ptg000004l:4402915-4407747 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27645 FUN_009240 52 84 37 15 28 ptg000004l:4402915-4407747 Q96AY4 2.22e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27646 FUN_009240 52 84 37 15 28 ptg000004l:4402915-4407747 Q96AY4 2.58e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27647 FUN_009240 52 84 37 15 28 ptg000004l:4402915-4407747 Q96AY4 7.71e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27648 FUN_009240 52 84 37 15 28 ptg000004l:4402915-4407747 Q96AY4 2.97e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27649 FUN_009240 52 84 37 15 28 ptg000004l:4402915-4407747 Q96AY4 4.25e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27650 FUN_009243 0 270 187 0 41 NA NA NA NA NA NA NA 27651 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 6.48e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27652 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 2.61e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27653 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 4.21e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27654 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 3.34e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27655 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 4.47e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27656 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 4.02e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27657 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 2.12e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27658 FUN_009242 151 260 75 174 66 ptg000004l:4433511-4436514 Q96AY4 1.16e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27659 FUN_009249 86 35 0 55 79 NA NA NA NA NA NA NA 27660 FUN_009248 129 37 6 56 174 NA NA NA NA NA NA NA 27661 FUN_039898 329 395 159 345 293 ptg000031l:1509290-1513996 Q9QZU7 1.86e-21 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 27662 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 1.73e-96 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27663 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 1.36e-95 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27664 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 3.15e-95 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27665 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 4.25e-95 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27666 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 1.55e-93 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27667 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 4.63e-93 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27668 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 1.64e-90 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27669 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 7.73e-87 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27670 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 2.49e-51 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27671 FUN_026655 30 35 1 5 47 ptg000020l:12064473-12065598 Q5R5U3 2.32e-42 Zinc finger protein 271 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0003677; GO:0005634; GO:0046872 27672 FUN_026654 44 49 0 0 0 NA NA NA NA NA NA NA 27673 FUN_026657 0 0 108 16 7 ptg000020l:12079242-12082334 Q9U6Y6 3.32e-27 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27674 FUN_026657 0 0 108 16 7 ptg000020l:12079242-12082334 Q9U6Y6 2.35e-26 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27675 FUN_026656 61 186 97 90 6 NA NA NA NA NA NA NA 27676 FUN_026651 0 11 0 15 7 NA NA NA NA NA NA NA 27677 FUN_026650 6 16 14 32 18 NA NA NA NA NA NA NA 27678 FUN_026653 21 0 0 0 0 NA NA NA NA NA NA NA 27679 FUN_026652 0 17 0 0 0 NA NA NA NA NA NA NA 27680 FUN_026659 0 0 0 0 11 NA NA NA NA NA NA NA 27681 FUN_026658 30 26 861 7 45 ptg000020l:12086769-12089149 Q9U6Y6 2.5e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27682 FUN_026658 30 26 861 7 45 ptg000020l:12086769-12089149 Q9U6Y6 2.4e-27 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27683 FUN_015459 16 42 20 293 66 ptg000009l:10427340-10429680 Q9ZQ47 2.18e-37 Glycine-rich domain-containing protein 1 (AtGRDP1) Arabidopsis thaliana (Mouse-ear cress) abscisic acid-activated signaling pathway [GO:0009738]; cellular response to osmotic stress [GO:0071470]; regulation of abscisic acid-activated signaling pathway [GO:0009787] GO:0005886; GO:0009738; GO:0009787; GO:0071470 27684 FUN_015451 522 173 215 408 511 NA NA NA NA NA NA NA 27685 FUN_015450 67 76 34 67 37 ptg000009l:10313378-10315008 Q9SR22 6.28e-69 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 27686 FUN_015453 4711 4425 1754 4957 2990 NA NA NA NA NA NA NA 27687 FUN_015452 1571 902 862 1952 1182 NA NA NA NA NA NA NA 27688 FUN_015455 42 0 0 0 43 NA NA NA NA NA NA NA 27689 FUN_015454 123 206 44 31 2415 NA NA NA NA NA NA NA 27690 FUN_015457 3364 28 0 40 11 NA NA NA NA NA NA NA 27691 FUN_015456 0 7 0 0 42 NA NA NA NA NA NA NA 27692 FUN_021026 0 37 0 0 0 NA NA NA NA NA NA NA 27693 FUN_021024 2 4 5 14 50 NA NA NA NA NA NA NA 27694 FUN_021020 2 0 0 8 4 NA NA NA NA NA NA NA 27695 FUN_017916 353 351 246 135 233 NA NA NA NA NA NA NA 27696 FUN_018725 7 0 0 0 0 NA NA NA NA NA NA NA 27697 FUN_017914 657 1497 876 6727 10452 NA NA NA NA NA NA NA 27698 FUN_018727 117 45 56 52 67 NA NA NA NA NA NA NA 27699 FUN_018720 122 74 59 227 108 NA NA NA NA NA NA NA 27700 FUN_017913 116 128 71 98 134 NA NA NA NA NA NA NA 27701 FUN_017910 76 44 22 84 31 NA NA NA NA NA NA NA 27702 FUN_018728 36 0 14 35 43 NA NA NA NA NA NA NA 27703 FUN_018729 0 0 0 27 0 NA NA NA NA NA NA NA 27704 FUN_017918 1277 1223 746 995 669 NA NA NA NA NA NA NA 27705 FUN_017919 3746 2621 2189 3084 2378 NA NA NA NA NA NA NA 27706 FUN_038285 4008 2544 4834 2413 2342 NA NA NA NA NA NA NA 27707 FUN_038284 8057 7621 3219 5815 3498 NA NA NA NA NA NA NA 27708 FUN_038287 30 0 26 33 51 NA NA NA NA NA NA NA 27709 FUN_038286 850 292 556 815 791 NA NA NA NA NA NA NA 27710 FUN_038281 371 93 501 395 372 NA NA NA NA NA NA NA 27711 FUN_038280 3576 3733 1433 3124 2948 NA NA NA NA NA NA NA 27712 FUN_038283 0 0 0 0 46 NA NA NA NA NA NA NA 27713 FUN_038282 523 276 114 369 140 NA NA NA NA NA NA NA 27714 FUN_025302 858 671 207 403 190 NA NA NA NA NA NA NA 27715 FUN_025303 4908 3882 2174 4373 3348 NA NA NA NA NA NA NA 27716 FUN_025301 105 28 14 21 37 NA NA NA NA NA NA NA 27717 FUN_038289 46 2 13 0 9 NA NA NA NA NA NA NA 27718 FUN_025307 16 0 0 51 0 NA NA NA NA NA NA NA 27719 FUN_025304 1792 1851 1046 1976 1908 NA NA NA NA NA NA NA 27720 FUN_025305 810 1083 498 699 386 NA NA NA NA NA NA NA 27721 FUN_024658 26 20 15 8 34 NA NA NA NA NA NA NA 27722 FUN_024657 100 84 119 0 80 NA NA NA NA NA NA NA 27723 FUN_024655 105 14 0 0 0 NA NA NA NA NA NA NA 27724 FUN_024654 0 23 0 13 0 NA NA NA NA NA NA NA 27725 FUN_024652 126 949 61 501 254 ptg000018l:9449035-9452614 Q7RTR2 5.19e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27726 FUN_024652 126 949 61 501 254 ptg000018l:9449035-9452614 Q7RTR2 3e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27727 FUN_024652 126 949 61 501 254 ptg000018l:9449035-9452614 Q7RTR2 7.84e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27728 FUN_024652 126 949 61 501 254 ptg000018l:9449035-9452614 Q7RTR2 4.7e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27729 FUN_024652 126 949 61 501 254 ptg000018l:9449035-9452614 Q7RTR2 9.7e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27730 FUN_024652 126 949 61 501 254 ptg000018l:9449035-9452614 Q7RTR2 7.48e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 27731 FUN_024651 393 622 236 240 130 NA NA NA NA NA NA NA 27732 FUN_024650 137 68 74 192 253 NA NA NA NA NA NA NA 27733 FUN_038139 1775 1120 1081 1980 1578 NA NA NA NA NA NA NA 27734 FUN_038138 303 541 81 186 198 NA NA NA NA NA NA NA 27735 FUN_038137 390 514 232 332 357 NA NA NA NA NA NA NA 27736 FUN_038136 34 0 0 9 17 NA NA NA NA NA NA NA 27737 FUN_038135 17 20 0 29 5 NA NA NA NA NA NA NA 27738 FUN_038133 727 286 482 661 682 ptg000027l:2925333-2928420 Q3T0T0 5.77e-25 Glycerophosphodiester phosphodiesterase 1 (Glycerophosphoinositol glycerophosphodiesterase GDE1) (EC 3.1.4.44) (Lysophospholipase D GDE1) (EC 3.1.4.-) (Membrane-interacting protein of RGS16) Bos taurus (Bovine) ethanolamine metabolic process [GO:0006580]; N-acylethanolamine metabolic process [GO:0070291]; phospholipid metabolic process [GO:0006644] GO:0004622; GO:0005886; GO:0006580; GO:0006644; GO:0008889; GO:0030659; GO:0046872; GO:0047395; GO:0070291 27739 FUN_038132 383 968 412 488 515 ptg000027l:2920455-2924590 Q8RB32 5.4e-24 NA NA NA NA 27740 FUN_038131 881 399 336 529 551 NA NA NA NA NA NA NA 27741 FUN_038130 1399 163 332 536 834 NA NA NA NA NA NA NA 27742 FUN_021977 0 0 0 6 18 NA NA NA NA NA NA NA 27743 FUN_021973 13 0 0 0 0 NA NA NA NA NA NA NA 27744 FUN_021978 11 0 3 28 88 NA NA NA NA NA NA NA 27745 FUN_001822 514 329 224 573 488 NA NA NA NA NA NA NA 27746 FUN_001825 0 0 0 0 13 NA NA NA NA NA NA NA 27747 FUN_001826 85 35 35 105 107 NA NA NA NA NA NA NA 27748 FUN_001828 48 76 23 12 66 NA NA NA NA NA NA NA 27749 FUN_035558 156 191 112 110 37 NA NA NA NA NA NA NA 27750 FUN_035556 226 534 120 814 438 NA NA NA NA NA NA NA 27751 FUN_035557 327 121 184 366 283 ptg000025l:9097121-9097595 Q91XQ0 3.44e-60 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003777; GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959 27752 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 1.69e-43 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27753 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 1.69e-43 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27754 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 5.19e-43 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27755 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 1.32e-41 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27756 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 1.85e-37 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27757 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 1.57e-32 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27758 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 6.62e-31 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27759 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 8.29e-30 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27760 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 9.39e-30 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27761 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 9.54e-29 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27762 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 5.04e-27 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27763 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 3.15e-25 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27764 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 4.19e-25 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27765 FUN_035554 3143 2179 2217 3713 4233 ptg000025l:9008011-9045227 M0R8U1 2.1e-23 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27766 FUN_030704 0 2 9 9 5 NA NA NA NA NA NA NA 27767 FUN_035553 172 93 165 483 597 ptg000025l:8990077-9007336 Q8TE73 6.15e-52 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27768 FUN_035553 172 93 165 483 597 ptg000025l:8990077-9007336 Q8TE73 7.02e-46 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27769 FUN_035553 172 93 165 483 597 ptg000025l:8990077-9007336 Q8TE73 1.31e-41 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27770 FUN_035553 172 93 165 483 597 ptg000025l:8990077-9007336 Q8TE73 3.26e-25 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0005524; GO:0005576; GO:0005737; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 27771 FUN_030707 51 6 20 16 96 NA NA NA NA NA NA NA 27772 FUN_031079 2298 1058 1152 1669 1537 NA NA NA NA NA NA NA 27773 FUN_031078 496 454 322 445 367 NA NA NA NA NA NA NA 27774 FUN_001799 816 338 331 492 495 NA NA NA NA NA NA NA 27775 FUN_001798 35 8 45 35 105 NA NA NA NA NA NA NA 27776 FUN_031071 0 0 18 25 49 NA NA NA NA NA NA NA 27777 FUN_031070 6929 4909 4795 4654 3233 NA NA NA NA NA NA NA 27778 FUN_031073 2 0 2 1 7 NA NA NA NA NA NA NA 27779 FUN_031072 16503 17581 5352 10287 5551 NA NA NA NA NA NA NA 27780 FUN_031075 3122 7695 1223 3324 1923 ptg000023l:16996571-16997453 P56965 8.86e-72 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) Bos taurus (Bovine) arginine catabolic process [GO:0006527]; arginine metabolic process [GO:0006525]; citrulline metabolic process [GO:0000052]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cellular response to hypoxia [GO:1900038]; negative regulation of vascular permeability [GO:0043116]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of nitric oxide biosynthetic process [GO:0045429]; protein nitrosylation [GO:0017014]; regulation of systemic arterial blood pressure [GO:0003073] GO:0000052; GO:0003073; GO:0006525; GO:0006527; GO:0006809; GO:0008270; GO:0008285; GO:0016403; GO:0016597; GO:0017014; GO:0043116; GO:0045429; GO:1900038 27781 FUN_031074 0 6 0 0 1 NA NA NA NA NA NA NA 27782 FUN_031077 190 23 175 172 520 NA NA NA NA NA NA NA 27783 FUN_031076 2451 1900 1165 1545 1062 NA NA NA NA NA NA NA 27784 FUN_039668 0 0 0 0 10 NA NA NA NA NA NA NA 27785 FUN_039669 0 10 0 0 13 NA NA NA NA NA NA NA 27786 FUN_007308 0 0 5 0 25 ptg000002l:1232974-1237136 P35067 2.18e-72 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27787 FUN_007309 31 0 66 0 125 ptg000002l:1239807-1244520 Q6LAF1 9.02e-45 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27788 FUN_039667 0 0 47 0 54 NA NA NA NA NA NA NA 27789 FUN_007302 10 45 4 11 94 NA NA NA NA NA NA NA 27790 FUN_039663 18 3 19 0 0 NA NA NA NA NA NA NA 27791 FUN_037950 268 91 180 140 153 NA NA NA NA NA NA NA 27792 FUN_037951 517 132 263 217 414 NA NA NA NA NA NA NA 27793 FUN_037952 642 325 509 775 748 NA NA NA NA NA NA NA 27794 FUN_037953 194 94 33 67 70 ptg000027l:791246-793063 Q12952 4.27e-41 Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; heart development [GO:0007507]; Peyer's patch morphogenesis [GO:0061146]; proteoglycan biosynthetic process [GO:0030166]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; visceral mesoderm-endoderm interaction involved in midgut development [GO:0007495] GO:0000785; GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0006357; GO:0007495; GO:0007507; GO:0008301; GO:0009653; GO:0030111; GO:0030154; GO:0030166; GO:0043565; GO:0061146 27795 FUN_037954 0 1 7 17 18 NA NA NA NA NA NA NA 27796 FUN_037955 177 91 76 78 108 ptg000027l:808611-809775 Q9PVY8 4.01e-41 Forkhead box protein C2-B (FoxC2-B) (FoxC2b) (Fork head domain-related protein 4') (FD-4') (xFD-4') (xFD4 B) Xenopus laevis (African clawed frog) mesoderm development [GO:0007498]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0007498; GO:0043565; GO:0045893; GO:0045944; GO:1990841 27797 FUN_037956 4006 1974 1465 1465 1598 NA NA NA NA NA NA NA 27798 FUN_037957 3719 1669 1392 2781 1999 NA NA NA NA NA NA NA 27799 FUN_037958 12 12 0 0 14 NA NA NA NA NA NA NA 27800 FUN_037959 1131 98 358 179 445 NA NA NA NA NA NA NA 27801 FUN_027685 0 40 10 31 18 NA NA NA NA NA NA NA 27802 FUN_027684 51 251 12 72 150 NA NA NA NA NA NA NA 27803 FUN_027686 0 51 0 0 4 NA NA NA NA NA NA NA 27804 FUN_027539 0 6 70 0 35 NA NA NA NA NA NA NA 27805 FUN_027536 1576 5724 1526 1589 1378 NA NA NA NA NA NA NA 27806 FUN_027535 0 0 0 0 13 NA NA NA NA NA NA NA 27807 FUN_027534 25 173 46 0 51 NA NA NA NA NA NA NA 27808 FUN_027533 303 195 104 85 122 NA NA NA NA NA NA NA 27809 FUN_027531 9 9 16 7 6 NA NA NA NA NA NA NA 27810 FUN_027530 15 9 0 0 9 NA NA NA NA NA NA NA 27811 FUN_006671 391 49 74 73 20 NA NA NA NA NA NA NA 27812 FUN_006670 472 124 178 451 50 NA NA NA NA NA NA NA 27813 FUN_006673 644 564 0 550 684 NA NA NA NA NA NA NA 27814 FUN_008216 229 266 209 180 256 ptg000002l:9372926-9374580 Q4KLT0 3.11e-46 E3 ubiquitin-protein ligase RNF217 (EC 2.3.2.31) (RING finger protein 217) Xenopus laevis (African clawed frog) NA GO:0004842; GO:0005737; GO:0016020; GO:0046872 27815 FUN_008211 50 7 0 4 7 NA NA NA NA NA NA NA 27816 FUN_005230 280 182 152 229 235 ntLink_8:32975676-32977876 Q8C9M2 2.96e-27 Coiled-coil domain-containing protein 15 Mus musculus (Mouse) NA GO:0005813 27817 FUN_005231 575 559 275 294 545 NA NA NA NA NA NA NA 27818 FUN_005232 2010 2460 1552 2337 1821 NA NA NA NA NA NA NA 27819 FUN_005233 599 318 399 666 373 NA NA NA NA NA NA NA 27820 FUN_005234 818 744 765 1797 978 ntLink_8:32998239-33031076 P21328 2.6e-21 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 27821 FUN_005234 818 744 765 1797 978 ntLink_8:32998239-33031076 P21328 2.6e-21 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 27822 FUN_005235 616 566 172 100 314 NA NA NA NA NA NA NA 27823 FUN_005236 63 59 6 43 13 NA NA NA NA NA NA NA 27824 FUN_005237 451 303 219 322 367 NA NA NA NA NA NA NA 27825 FUN_005238 246 234 172 109 204 NA NA NA NA NA NA NA 27826 FUN_005239 93 52 38 83 45 ntLink_8:33045961-33047527 Q6GPB8 8.65e-157 Lariat debranching enzyme A (EC 3.1.4.-) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; RNA splicing, via transesterification reactions [GO:0000375] GO:0000375; GO:0005634; GO:0006397; GO:0008419 27827 FUN_004543 0 0 1 1 7 NA NA NA NA NA NA NA 27828 FUN_004542 5 2 41 31 220 NA NA NA NA NA NA NA 27829 FUN_004545 0 0 0 0 13 NA NA NA NA NA NA NA 27830 FUN_004544 262 80 0 19 138 NA NA NA NA NA NA NA 27831 FUN_004547 627 400 203 678 440 NA NA NA NA NA NA NA 27832 FUN_004546 480 241 235 323 356 ntLink_8:24243456-24251309 Q5ZI43 7.12e-26 Snurportin-1 (RNA U transporter 1) Gallus gallus (Chicken) protein import into nucleus [GO:0006606]; snRNA import into nucleus [GO:0061015] GO:0003723; GO:0005654; GO:0005737; GO:0006606; GO:0042564; GO:0061015; GO:0061608 27833 FUN_004549 229 360 160 433 155 NA NA NA NA NA NA NA 27834 FUN_004548 18 42 19 50 14 NA NA NA NA NA NA NA 27835 FUN_016439 1015 929 919 2046 1134 ptg000011l:3098532-3101292 Q5RDX2 1.77e-43 Suppressor of cytokine signaling 4 (SOCS-4) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) intracellular signal transduction [GO:0035556]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567] GO:0007175; GO:0016567; GO:0032436; GO:0035556 27836 FUN_037046 510 290 230 356 234 NA NA NA NA NA NA NA 27837 FUN_006954 52 0 95 55 131 ptg000001l:18754222-18756844 Q9U6Y6 1.01e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27838 FUN_006954 52 0 95 55 131 ptg000001l:18754222-18756844 Q9U6Y6 2.08e-27 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27839 FUN_037044 149 81 101 174 261 NA NA NA NA NA NA NA 27840 FUN_037045 80 22 71 77 112 NA NA NA NA NA NA NA 27841 FUN_037042 1516 1629 1480 2846 2399 NA NA NA NA NA NA NA 27842 FUN_037043 14813 31491 13686 59860 33704 NA NA NA NA NA NA NA 27843 FUN_037040 14 0 0 10 0 NA NA NA NA NA NA NA 27844 FUN_016437 706 792 566 1001 1329 NA NA NA NA NA NA NA 27845 FUN_006956 0 0 29 0 22 ptg000001l:18771622-18772479 Q9U6Y6 2.54e-30 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27846 FUN_006956 0 0 29 0 22 ptg000001l:18771622-18772479 Q9U6Y6 8.69e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 27847 FUN_037048 22938 24444 10914 21935 19826 ptg000026l:4990990-4994193 Q962Q6 1.83e-26 40S ribosomal protein S24 Spodoptera frugiperda (Fall armyworm) translation [GO:0006412] GO:0003735; GO:0005840; GO:0006412; GO:1990904 27848 FUN_037049 180 146 129 24 24 NA NA NA NA NA NA NA 27849 FUN_016435 18 59 52 12 7 NA NA NA NA NA NA NA 27850 FUN_032678 179 541 317 130 146 ptg000023l:34868503-34877632 Q923S9 6.85e-50 Ras-related protein Rab-30 Mus musculus (Mouse) Golgi organization [GO:0007030]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005801; GO:0005802; GO:0007030; GO:0016020; GO:0016192; GO:0031985; GO:0032482; GO:0043231 27851 FUN_032679 463 141 162 168 146 NA NA NA NA NA NA NA 27852 FUN_032676 1830 952 1182 1361 1119 NA NA NA NA NA NA NA 27853 FUN_032677 216 112 114 174 205 NA NA NA NA NA NA NA 27854 FUN_032674 24 0 0 0 0 NA NA NA NA NA NA NA 27855 FUN_032675 99 83 96 96 26 NA NA NA NA NA NA NA 27856 FUN_032672 117 45 107 0 0 NA NA NA NA NA NA NA 27857 FUN_032673 45 0 7 0 0 NA NA NA NA NA NA NA 27858 FUN_032670 372 45 108 0 0 ptg000023l:34779839-34790542 Q6V0K7 7.98e-21 Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein) Rattus norvegicus (Rat) urate homeostasis [GO:1903118] GO:0005201; GO:0005509; GO:0005615; GO:0005635; GO:0009986; GO:1903118 27859 FUN_032671 191 83 230 61 0 ptg000023l:34799231-34822568 Q91X17 3.94e-23 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 27860 FUN_016430 284 144 105 175 309 ptg000011l:2972236-2973045 Q5UQN4 2.63e-29 Uncharacterized protein L432 Acanthamoeba polyphaga mimivirus (APMV) NA GO:0016787 27861 FUN_003816 8 20 0 0 3 NA NA NA NA NA NA NA 27862 FUN_004849 6 0 43 22 103 NA NA NA NA NA NA NA 27863 FUN_035115 953 655 150 130 107 NA NA NA NA NA NA NA 27864 FUN_034630 58 0 9 0 14 NA NA NA NA NA NA NA 27865 FUN_034634 0 0 0 0 61 NA NA NA NA NA NA NA 27866 FUN_034635 0 0 0 0 10 NA NA NA NA NA NA NA 27867 FUN_034639 0 0 5 0 132 NA NA NA NA NA NA NA 27868 FUN_004743 987 705 864 1305 2720 NA NA NA NA NA NA NA 27869 FUN_004847 1 0 9 0 2 NA NA NA NA NA NA NA 27870 FUN_005498 26 0 7 14 0 NA NA NA NA NA NA NA 27871 FUN_005494 0 0 0 0 8 NA NA NA NA NA NA NA 27872 FUN_005495 46 0 28 0 78 ntLink_8:36191977-36200946 Q6LAF1 1.86e-33 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27873 FUN_005495 46 0 28 0 78 ntLink_8:36191977-36200946 Q6LAF1 1.86e-33 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 27874 FUN_005497 0 0 0 0 12 NA NA NA NA NA NA NA 27875 FUN_005490 0 0 14 12 22 NA NA NA NA NA NA NA 27876 FUN_005492 7 0 1 0 18 NA NA NA NA NA NA NA 27877 FUN_031743 238 217 74 165 76 NA NA NA NA NA NA NA 27878 FUN_004740 9924 5143 3757 4915 2828 ntLink_8:26405465-26409434 Q92963 3.78e-47 GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) Homo sapiens (Human) Ras protein signal transduction [GO:0007265]; signal transduction [GO:0007165] GO:0003924; GO:0003925; GO:0005516; GO:0005525; GO:0005886; GO:0007165; GO:0007265; GO:0019003 27879 FUN_003535 10 10 54 0 162 NA NA NA NA NA NA NA 27880 FUN_031741 1072 576 833 1429 931 NA NA NA NA NA NA NA 27881 FUN_031747 7 57 110 74 14 ptg000023l:24965602-24967595 G3M4F8 2.95e-24 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 27882 FUN_003536 11 0 20 0 100 NA NA NA NA NA NA NA 27883 FUN_031746 59 6 25 70 82 NA NA NA NA NA NA NA 27884 FUN_007896 2371 1257 935 2763 1588 ptg000002l:6013934-6040956 Q80XK6 3.06e-47 Autophagy-related protein 2 homolog B Mus musculus (Mouse) autophagosome assembly [GO:0000045]; autophagy of mitochondrion [GO:0000422]; late nucleophagy [GO:0044805]; piecemeal microautophagy of the nucleus [GO:0034727]; reticulophagy [GO:0061709] GO:0000045; GO:0000407; GO:0000422; GO:0005789; GO:0005811; GO:0019898; GO:0032266; GO:0034045; GO:0034727; GO:0044805; GO:0061709; GO:0120013 27885 FUN_007897 825 4832 149 1211 59 NA NA NA NA NA NA NA 27886 FUN_007894 1450 267 570 815 1593 NA NA NA NA NA NA NA 27887 FUN_007895 3531 1605 1795 2785 3378 NA NA NA NA NA NA NA 27888 FUN_007892 1203 891 1084 1438 1521 NA NA NA NA NA NA NA 27889 FUN_007893 288 149 310 285 470 ptg000002l:5975947-5978459 Q502K1 5.01e-29 Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic DNA fragmentation [GO:0006309] GO:0000014; GO:0003676; GO:0004519; GO:0004521; GO:0005634; GO:0005743; GO:0006309; GO:0008409; GO:0046872 27890 FUN_007893 288 149 310 285 470 ptg000002l:5975947-5978459 Q502K1 5.01e-24 Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1) Danio rerio (Zebrafish) (Brachydanio rerio) apoptotic DNA fragmentation [GO:0006309] GO:0000014; GO:0003676; GO:0004519; GO:0004521; GO:0005634; GO:0005743; GO:0006309; GO:0008409; GO:0046872 27891 FUN_007890 1043 732 495 1033 921 NA NA NA NA NA NA NA 27892 FUN_010224 0 22 0 0 0 NA NA NA NA NA NA NA 27893 FUN_031744 545 402 76 583 311 NA NA NA NA NA NA NA 27894 FUN_004749 3580 2659 2296 4298 2798 NA NA NA NA NA NA NA 27895 FUN_007898 2932 1310 962 824 727 NA NA NA NA NA NA NA 27896 FUN_041920 3290 3970 1818 2191 1663 NA NA NA NA NA NA NA 27897 FUN_041921 2391 2074 1636 2456 1679 ptg000035l:8879350-8890478 Q68F70 4.34e-50 Integrator complex subunit 4 (Int4) Xenopus laevis (African clawed frog) NA GO:0005634 27898 FUN_041921 2391 2074 1636 2456 1679 ptg000035l:8879350-8890478 Q68F70 4.03e-25 Integrator complex subunit 4 (Int4) Xenopus laevis (African clawed frog) NA GO:0005634 27899 FUN_041922 10447 29611 10484 17741 6320 NA NA NA NA NA NA NA 27900 FUN_041924 1250 742 569 1199 756 ptg000035l:8909516-8926248 Q9H8V3 9.29e-29 Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; activation of protein kinase activity [GO:0032147]; bicellular tight junction assembly [GO:0070830]; cell differentiation [GO:0030154]; cell morphogenesis [GO:0000902]; cellular response to calcium ion [GO:0071277]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to ionizing radiation [GO:0071479]; intracellular signal transduction [GO:0035556]; mitotic cytokinesis [GO:0000281]; nervous system development [GO:0007399]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cytokinesis [GO:0032467]; positive regulation of GTPase activity [GO:0043547]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of protein import into nucleus [GO:0042307]; protein homooligomerization [GO:0051260]; protein transport [GO:0015031]; regulation of attachment of spindle microtubules to kinetochore [GO:0051988]; regulation of cytokinesis, actomyosin contractile ring assembly [GO:2000431]; regulation of protein kinase activity [GO:0045859]; regulation of small GTPase mediated signal transduction [GO:0051056] GO:0000281; GO:0000902; GO:0005085; GO:0005096; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0005829; GO:0005911; GO:0005923; GO:0005938; GO:0007399; GO:0015031; GO:0016604; GO:0030154; GO:0030496; GO:0031267; GO:0032147; GO:0032154; GO:0032467; GO:0035556; GO:0042307; GO:0042803; GO:0043065; GO:0043123; GO:0043547; GO:0045666; GO:0045859; GO:0051056; GO:0051260; GO:0051988; GO:0070301; GO:0070830; GO:0071277; GO:0071479; GO:0072686; GO:0090630; GO:0097149; GO:2000431 27901 FUN_041925 0 0 16 12 13 NA NA NA NA NA NA NA 27902 FUN_041926 0 7 0 11 171 NA NA NA NA NA NA NA 27903 FUN_041927 2264 2259 1600 4258 1935 NA NA NA NA NA NA NA 27904 FUN_041928 706 469 396 662 409 ptg000035l:8984207-8996943 Q8BG19 4.58e-39 Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 4) Mus musculus (Mouse) endoplasmic reticulum unfolded protein response [GO:0030968]; outer hair cell apoptotic process [GO:1905584]; positive regulation of endoplasmic reticulum calcium ion concentration [GO:0032470]; protein O-linked mannosylation [GO:0035269]; sensory perception of sound [GO:0007605] GO:0000030; GO:0004169; GO:0005783; GO:0007605; GO:0016020; GO:0030968; GO:0032470; GO:0035269; GO:0051117; GO:1905584 27905 FUN_041929 3866 4496 4050 4145 2825 NA NA NA NA NA NA NA 27906 FUN_001076 3038 1866 1882 2805 2200 NA NA NA NA NA NA NA 27907 FUN_001077 736 311 426 842 567 NA NA NA NA NA NA NA 27908 FUN_001074 227 100 166 275 179 NA NA NA NA NA NA NA 27909 FUN_001075 482 261 352 957 313 NA NA NA NA NA NA NA 27910 FUN_001072 633 632 181 401 426 NA NA NA NA NA NA NA 27911 FUN_001073 10 33 0 13 17 NA NA NA NA NA NA NA 27912 FUN_001070 55 32 0 7 0 NA NA NA NA NA NA NA 27913 FUN_001071 1676 1089 784 876 1217 NA NA NA NA NA NA NA 27914 FUN_001078 411 549 147 286 213 NA NA NA NA NA NA NA 27915 FUN_001079 2129 1448 1070 1694 1207 NA NA NA NA NA NA NA 27916 FUN_034098 175 76 91 78 374 ptg000024l:4849332-4861821 Q66PY1 2.13e-24 Signal peptide, CUB and EGF-like domain-containing protein 3 Mus musculus (Mouse) positive regulation of BMP signaling pathway [GO:0030513]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of smoothened signaling pathway [GO:0045880]; signal transduction [GO:0007165] GO:0005509; GO:0005615; GO:0005886; GO:0007165; GO:0009986; GO:0030513; GO:0036122; GO:0042802; GO:0045669; GO:0045880; GO:0070700 27917 FUN_034099 189 234 190 345 243 NA NA NA NA NA NA NA 27918 FUN_034094 225 77 53 78 171 NA NA NA NA NA NA NA 27919 FUN_034095 778 156 112 258 155 NA NA NA NA NA NA NA 27920 FUN_034096 1132 327 686 905 1002 NA NA NA NA NA NA NA 27921 FUN_034097 78 34 37 29 84 ptg000024l:4829888-4831617 Q5PP32 5.16e-31 WAT1-related protein At3g45870 Arabidopsis thaliana (Mouse-ear cress) NA GO:0005886; GO:0022857 27922 FUN_034090 2187 812 720 1780 971 ptg000024l:4729794-4752426 O14727 1.2e-80 Apoptotic protease-activating factor 1 (APAF-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c [GO:0008635]; aging [GO:0007568]; apoptotic process [GO:0006915]; cardiac muscle cell apoptotic process [GO:0010659]; cell differentiation [GO:0030154]; cellular response to transforming growth factor beta stimulus [GO:0071560]; forebrain development [GO:0030900]; intrinsic apoptotic signaling pathway [GO:0097193]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; kidney development [GO:0001822]; nervous system development [GO:0007399]; neural tube closure [GO:0001843]; neuron apoptotic process [GO:0051402]; positive regulation of apoptotic process [GO:0043065]; positive regulation of apoptotic signaling pathway [GO:2001235]; regulation of apoptotic DNA fragmentation [GO:1902510]; regulation of apoptotic process [GO:0042981]; response to G1 DNA damage checkpoint signaling [GO:0072432]; response to hypoxia [GO:0001666]; response to nutrient [GO:0007584] GO:0000166; GO:0001666; GO:0001822; GO:0001843; GO:0005524; GO:0005576; GO:0005634; GO:0005829; GO:0006915; GO:0006919; GO:0007399; GO:0007568; GO:0007584; GO:0008635; GO:0008656; GO:0010659; GO:0030154; GO:0030900; GO:0031072; GO:0032991; GO:0034774; GO:0042802; GO:0042981; GO:0043065; GO:0043293; GO:0043531; GO:0051402; GO:0070059; GO:0070062; GO:0071560; GO:0072432; GO:0097193; GO:0097202; GO:1902510; GO:1904813; GO:2001235 27923 FUN_034091 19655 19143 10531 15762 15544 NA NA NA NA NA NA NA 27924 FUN_034092 1788 2099 1356 1461 1147 NA NA NA NA NA NA NA 27925 FUN_034093 1343 1272 700 892 869 NA NA NA NA NA NA NA 27926 FUN_035941 1656 2084 966 1619 1021 NA NA NA NA NA NA NA 27927 FUN_035940 1070 995 471 708 533 NA NA NA NA NA NA NA 27928 FUN_035943 0 10 0 34 21 NA NA NA NA NA NA NA 27929 FUN_035942 814 803 970 772 801 NA NA NA NA NA NA NA 27930 FUN_035945 5517 4548 3853 6274 6237 NA NA NA NA NA NA NA 27931 FUN_035944 306 199 66 171 113 NA NA NA NA NA NA NA 27932 FUN_035947 4115 4560 3708 3772 3952 NA NA NA NA NA NA NA 27933 FUN_035946 108 3 47 32 47 ptg000025l:13505998-13507291 Q5RCM6 1.97e-25 Suppressor of cytokine signaling 6 (SOCS-6) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) intracellular signal transduction [GO:0035556]; negative regulation of signal transduction [GO:0009968]; negative regulation of T cell activation [GO:0050868]; proteasomal protein catabolic process [GO:0010498]; protein ubiquitination [GO:0016567]; regulation of growth [GO:0040008] GO:0001772; GO:0009968; GO:0010498; GO:0016567; GO:0035556; GO:0040008; GO:0050868 27934 FUN_035949 3 13 8 90 10 NA NA NA NA NA NA NA 27935 FUN_035948 298 347 137 625 284 NA NA NA NA NA NA NA 27936 FUN_041923 48533 32603 24461 40670 23506 NA NA NA NA NA NA NA 27937 FUN_017922 1551 501 659 1134 967 NA NA NA NA NA NA NA 27938 FUN_029210 592 493 503 825 1030 ptg000022l:9319199-9340253 Q9SR22 1.22e-69 Pectin acetylesterase 5 (EC 3.1.1.-) Arabidopsis thaliana (Mouse-ear cress) cell wall organization [GO:0071555] GO:0005576; GO:0009505; GO:0052793; GO:0071555 27939 FUN_029213 102 7 0 21 47 NA NA NA NA NA NA NA 27940 FUN_029214 0 37 28 41 47 NA NA NA NA NA NA NA 27941 FUN_029216 123 119 84 96 178 ptg000022l:9361271-9365043 Q9BYN7 2.17e-36 Zinc finger protein 341 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0001216; GO:0003677; GO:0005634; GO:0006355; GO:0046872 27942 FUN_029218 45 0 15 19 21 NA NA NA NA NA NA NA 27943 FUN_029219 62 121 76 118 237 NA NA NA NA NA NA NA 27944 FUN_043386 350 226 292 389 422 ptg000047l:7819647-7833423 Q924Z9 5.99e-44 Netrin-1 Rattus norvegicus (Rat) animal organ morphogenesis [GO:0009887]; anterior/posterior axon guidance [GO:0033564]; apoptotic process [GO:0006915]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell mediated immunity [GO:0019724]; B cell proliferation [GO:0042100]; Cdc42 protein signal transduction [GO:0032488]; cell population proliferation [GO:0008283]; cell-cell adhesion [GO:0098609]; chemorepulsion of axon [GO:0061643]; dendrite development [GO:0016358]; glial cell proliferation [GO:0014009]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mammary gland duct morphogenesis [GO:0060603]; motor neuron axon guidance [GO:0008045]; motor neuron migration [GO:0097475]; negative regulation of axon extension [GO:0030517]; neuron migration [GO:0001764]; nuclear migration [GO:0007097]; positive regulation of axon extension [GO:0045773]; positive regulation of cell motility [GO:2000147]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of glial cell proliferation [GO:0060252]; Ras protein signal transduction [GO:0007265]; regulation of cell migration [GO:0030334]; regulation of glial cell migration [GO:1903975]; regulation of synapse assembly [GO:0051963]; substrate-dependent cell migration, cell extension [GO:0006930]; T cell mediated immunity [GO:0002456]; tissue development [GO:0009888] GO:0001764; GO:0002456; GO:0005125; GO:0005576; GO:0005604; GO:0005737; GO:0006915; GO:0006930; GO:0007097; GO:0007265; GO:0007409; GO:0007411; GO:0008045; GO:0008283; GO:0008284; GO:0009887; GO:0009888; GO:0014009; GO:0016358; GO:0019724; GO:0030334; GO:0030517; GO:0030879; GO:0031012; GO:0032488; GO:0033564; GO:0042100; GO:0042472; GO:0045773; GO:0051963; GO:0060252; GO:0060603; GO:0061643; GO:0097475; GO:0098609; GO:1903975; GO:2000147 27945 FUN_043387 1246 842 645 1275 1297 ptg000047l:7833747-7858998 P11047 1.2e-102 Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; endoderm development [GO:0007492]; extracellular matrix disassembly [GO:0022617]; hemidesmosome assembly [GO:0031581]; maintenance of blood-brain barrier [GO:0035633]; positive regulation of cell adhesion [GO:0045785]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; protein-containing complex assembly [GO:0065003]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005615; GO:0005788; GO:0007155; GO:0007492; GO:0009887; GO:0009888; GO:0016477; GO:0022617; GO:0031581; GO:0034446; GO:0035633; GO:0043259; GO:0043260; GO:0045785; GO:0050679; GO:0051149; GO:0062023; GO:0065003; GO:0070062; GO:0098637; GO:0110011; GO:2001046 27946 FUN_043387 1246 842 645 1275 1297 ptg000047l:7833747-7858998 P11047 1.27e-36 Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; endoderm development [GO:0007492]; extracellular matrix disassembly [GO:0022617]; hemidesmosome assembly [GO:0031581]; maintenance of blood-brain barrier [GO:0035633]; positive regulation of cell adhesion [GO:0045785]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; protein-containing complex assembly [GO:0065003]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005615; GO:0005788; GO:0007155; GO:0007492; GO:0009887; GO:0009888; GO:0016477; GO:0022617; GO:0031581; GO:0034446; GO:0035633; GO:0043259; GO:0043260; GO:0045785; GO:0050679; GO:0051149; GO:0062023; GO:0065003; GO:0070062; GO:0098637; GO:0110011; GO:2001046 27947 FUN_043387 1246 842 645 1275 1297 ptg000047l:7833747-7858998 P11047 4.81e-28 Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) Homo sapiens (Human) animal organ morphogenesis [GO:0009887]; cell adhesion [GO:0007155]; cell migration [GO:0016477]; endoderm development [GO:0007492]; extracellular matrix disassembly [GO:0022617]; hemidesmosome assembly [GO:0031581]; maintenance of blood-brain barrier [GO:0035633]; positive regulation of cell adhesion [GO:0045785]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of integrin-mediated signaling pathway [GO:2001046]; positive regulation of muscle cell differentiation [GO:0051149]; protein-containing complex assembly [GO:0065003]; regulation of basement membrane organization [GO:0110011]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888] GO:0005201; GO:0005576; GO:0005604; GO:0005606; GO:0005615; GO:0005788; GO:0007155; GO:0007492; GO:0009887; GO:0009888; GO:0016477; GO:0022617; GO:0031581; GO:0034446; GO:0035633; GO:0043259; GO:0043260; GO:0045785; GO:0050679; GO:0051149; GO:0062023; GO:0065003; GO:0070062; GO:0098637; GO:0110011; GO:2001046 27948 FUN_043385 3732 2647 2159 4272 2086 ptg000047l:7795303-7810185 Q8R4G0 1.03e-36 Netrin-G1 (Laminet-1) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; axonogenesis [GO:0007409]; basement membrane assembly [GO:0070831]; cell migration [GO:0016477]; modulation of chemical synaptic transmission [GO:0050804]; regulation of neuron migration [GO:2001222]; regulation of neuron projection arborization [GO:0150011]; regulation of neuron projection development [GO:0010975]; substrate adhesion-dependent cell spreading [GO:0034446]; synaptic membrane adhesion [GO:0099560]; tissue development [GO:0009888] GO:0005886; GO:0007409; GO:0009887; GO:0009888; GO:0010975; GO:0016477; GO:0034446; GO:0043256; GO:0048787; GO:0050804; GO:0050839; GO:0070831; GO:0098632; GO:0098685; GO:0098978; GO:0099560; GO:0150011; GO:2001222 27949 FUN_043382 50 76 0 72 122 NA NA NA NA NA NA NA 27950 FUN_043383 142 54 69 152 97 NA NA NA NA NA NA NA 27951 FUN_043380 3670 1465 1203 1859 1276 ptg000047l:7744398-7748736 P15848 7.73e-21 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Homo sapiens (Human) autophagy [GO:0006914]; central nervous system development [GO:0007417]; colon epithelial cell migration [GO:0061580]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005576; GO:0005739; GO:0005764; GO:0005788; GO:0005791; GO:0005794; GO:0006914; GO:0007040; GO:0007041; GO:0007417; GO:0007584; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0035578; GO:0043202; GO:0043627; GO:0046872; GO:0051597; GO:0061580; GO:0070062; GO:1904813 27952 FUN_043381 2544 833 622 1527 691 ptg000047l:7750370-7760192 P50429 5.41e-21 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Mus musculus (Mouse) anterior head development [GO:0097065]; autophagy [GO:0006914]; central nervous system development [GO:0007417]; chondroitin sulfate catabolic process [GO:0030207]; colon epithelial cell migration [GO:0061580]; dermatan sulfate catabolic process [GO:0030209]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632]; response to estrogen [GO:0043627]; response to methylmercury [GO:0051597]; response to nutrient [GO:0007584]; response to pH [GO:0009268] GO:0003943; GO:0004065; GO:0005739; GO:0005764; GO:0005791; GO:0005794; GO:0006914; GO:0007417; GO:0007584; GO:0008484; GO:0009268; GO:0009986; GO:0010632; GO:0010976; GO:0030207; GO:0030209; GO:0043627; GO:0043890; GO:0046872; GO:0051597; GO:0061580; GO:0097065 27953 FUN_012403 37 23 50 67 78 NA NA NA NA NA NA NA 27954 FUN_012402 179 166 32 71 76 NA NA NA NA NA NA NA 27955 FUN_012401 23 22 0 53 73 NA NA NA NA NA NA NA 27956 FUN_012400 770 574 345 442 167 NA NA NA NA NA NA NA 27957 FUN_012407 15 87 177 54 81 NA NA NA NA NA NA NA 27958 FUN_012406 168 1586 0 4 3363 NA NA NA NA NA NA NA 27959 FUN_043388 138 122 74 153 95 NA NA NA NA NA NA NA 27960 FUN_043389 2958 1543 1468 2300 1311 NA NA NA NA NA NA NA 27961 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 2.49e-49 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27962 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.14e-39 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27963 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.02e-37 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27964 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 4.19e-35 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27965 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 4.46e-33 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27966 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 8.6e-32 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27967 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.37e-31 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27968 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 3.75e-31 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27969 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 3.62e-30 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27970 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.95e-28 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27971 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.53e-27 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27972 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 7.28e-26 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27973 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.57e-25 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27974 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.57e-25 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27975 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.68e-24 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27976 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.98e-24 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27977 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.27e-23 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27978 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 1.76e-21 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27979 FUN_006858 3200 1832 1812 3594 2899 ptg000001l:17460204-17513068 Q8NCM8 2.42e-21 Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) Homo sapiens (Human) cilium assembly [GO:0060271]; coronary vasculature development [GO:0060976]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic limb morphogenesis [GO:0030326]; forebrain development [GO:0030900]; Golgi organization [GO:0007030]; intraciliary retrograde transport [GO:0035721]; kidney development [GO:0001822]; microtubule-based movement [GO:0007018]; non-motile cilium assembly [GO:1905515]; positive regulation of smoothened signaling pathway [GO:0045880]; protein localization to cilium [GO:0061512]; protein processing [GO:0016485]; spinal cord motor neuron differentiation [GO:0021522] GO:0001822; GO:0003774; GO:0005524; GO:0005794; GO:0005868; GO:0005874; GO:0005886; GO:0005929; GO:0005930; GO:0007018; GO:0007030; GO:0007368; GO:0008569; GO:0009953; GO:0016485; GO:0021522; GO:0030286; GO:0030326; GO:0030900; GO:0031514; GO:0035721; GO:0045177; GO:0045505; GO:0045880; GO:0051959; GO:0060271; GO:0060976; GO:0061512; GO:0070062; GO:0097542; GO:1905515 27980 FUN_016579 501 909 267 685 311 NA NA NA NA NA NA NA 27981 FUN_016578 1511 653 618 798 1199 ptg000011l:4940497-4946318 Q96FI4 3.01e-24 Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (FPG1) (Nei homolog 1) (NEH1) (Nei-like protein 1) Homo sapiens (Human) base-excision repair [GO:0006284]; base-excision repair, gap-filling [GO:0006287]; depyrimidination [GO:0045008]; negative regulation of nuclease activity [GO:0032074]; response to oxidative stress [GO:0006979] GO:0003684; GO:0003906; GO:0005634; GO:0005654; GO:0005694; GO:0005737; GO:0005815; GO:0005829; GO:0006284; GO:0006287; GO:0006979; GO:0008022; GO:0008270; GO:0016798; GO:0019104; GO:0032074; GO:0045008; GO:0140078 27982 FUN_016573 137 49 80 137 100 ptg000011l:4907415-4910645 P18130 1.58e-39 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 27983 FUN_016572 2491 1878 1099 1950 1964 NA NA NA NA NA NA NA 27984 FUN_006853 78 41 44 19 70 NA NA NA NA NA NA NA 27985 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 1.6e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27986 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 5.9e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27987 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 1.09e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27988 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 5.69e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27989 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 1.34e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27990 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 8.3e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27991 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 9.71e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27992 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 1.75e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27993 FUN_016570 24 31 41 45 44 ptg000011l:4871389-4877705 Q96AY4 4.01e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 27994 FUN_006855 204 232 165 212 337 NA NA NA NA NA NA NA 27995 FUN_016576 28 0 43 95 7 ptg000011l:4928209-4929592 P18130 2.62e-41 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Bos taurus (Bovine) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907]; regulation of cardiac muscle contraction [GO:0055117] GO:0001996; GO:0004930; GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0007200; GO:0007204; GO:0007267; GO:0031965; GO:0043410; GO:0045907; GO:0046982; GO:0055117; GO:0071880 27996 FUN_006856 431 263 122 260 385 ptg000001l:17436837-17440480 P51986 1.67e-47 G2/mitotic-specific cyclin-A Hydra viridissima (Green hydra) (Chlorohydra viridissima) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772] GO:0016538; GO:0044772; GO:0051301 27997 FUN_012219 35 0 19 28 17 NA NA NA NA NA NA NA 27998 FUN_016382 2562 4069 1188 1407 952 ptg000011l:2518296-2519431 Q3MHX1 2.96e-37 COMM domain-containing protein 7 Bos taurus (Bovine) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0031410; GO:0032088; GO:0033209; GO:0045892; GO:0051059 27999 FUN_016383 547 362 183 277 297 NA NA NA NA NA NA NA 28000 FUN_016036 1012 896 558 789 352 NA NA NA NA NA NA NA 28001 FUN_042389 5 0 0 0 19 NA NA NA NA NA NA NA 28002 FUN_003202 0 0 3 0 8 NA NA NA NA NA NA NA 28003 FUN_042387 0 0 0 0 17 NA NA NA NA NA NA NA 28004 FUN_042386 7 0 8 0 8 NA NA NA NA NA NA NA 28005 FUN_042381 71 49 62 47 241 NA NA NA NA NA NA NA 28006 FUN_042382 0 0 0 0 19 NA NA NA NA NA NA NA 28007 FUN_028162 646 280 322 349 513 NA NA NA NA NA NA NA 28008 FUN_028165 3569 2213 815 1341 996 NA NA NA NA NA NA NA 28009 FUN_028167 547 464 266 453 655 NA NA NA NA NA NA NA 28010 FUN_028166 7 178 37 169 332 ptg000021l:16375361-16377504 Q5SUE8 2.19e-23 Ankyrin repeat domain-containing protein 40 Mus musculus (Mouse) NA NA 28011 FUN_028169 1014 512 355 499 347 NA NA NA NA NA NA NA 28012 FUN_019421 0 0 0 0 8 NA NA NA NA NA NA NA 28013 FUN_040277 10817 11110 459 9062 55 NA NA NA NA NA NA NA 28014 FUN_010596 53 15 268 86 108 ptg000007l:559063-562943 O82504 2.15e-24 RNA-dependent RNA polymerase 2 (AtRDRP2) (EC 2.7.7.48) (Protein SILENCING MOVEMENT DEFICIENT 1) (RNA-directed RNA polymerase 2) Arabidopsis thaliana (Mouse-ear cress) defense response to fungus [GO:0050832]; RNA biosynthetic process [GO:0032774]; RNA-templated transcription [GO:0001172]; siRNA processing [GO:0030422]; siRNA-mediated long-distance post-transcriptional gene silencing [GO:0010495] GO:0001172; GO:0003727; GO:0003968; GO:0005634; GO:0005654; GO:0005730; GO:0010495; GO:0030422; GO:0031380; GO:0032774; GO:0046872; GO:0050832; GO:0071667 28015 FUN_010595 27 0 20 24 0 NA NA NA NA NA NA NA 28016 FUN_043658 770 998 508 468 418 NA NA NA NA NA NA NA 28017 FUN_043659 537 748 517 355 295 NA NA NA NA NA NA NA 28018 FUN_010594 0 0 2 72 7 NA NA NA NA NA NA NA 28019 FUN_010809 232 216 140 116 185 ptg000007l:3053990-3057448 Q49LS4 3.72e-35 XK-related protein 4 [Cleaved into: XK-related protein 4, processed form] Pan troglodytes (Chimpanzee) apoptotic process involved in development [GO:1902742]; engulfment of apoptotic cell [GO:0043652]; phosphatidylserine exposure on apoptotic cell surface [GO:0070782] GO:0005886; GO:0016020; GO:0017128; GO:0042803; GO:0043652; GO:0070782; GO:1902742 28020 FUN_010808 1493 550 639 1062 1070 NA NA NA NA NA NA NA 28021 FUN_010805 503 426 306 397 420 NA NA NA NA NA NA NA 28022 FUN_010804 4854 5186 2710 5585 3672 NA NA NA NA NA NA NA 28023 FUN_043652 63 58 20 14 31 NA NA NA NA NA NA NA 28024 FUN_043653 212 169 40 77 71 NA NA NA NA NA NA NA 28025 FUN_010800 57 24 36 86 148 NA NA NA NA NA NA NA 28026 FUN_010591 56 0 52 92 90 NA NA NA NA NA NA NA 28027 FUN_040270 18 11 27 0 24 ptg000031l:6160268-6161198 O46639 2.99e-22 Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberin receptor) Bos taurus (Bovine) phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200] GO:0004997; GO:0005886; GO:0007200 28028 FUN_007104 224 55 78 354 295 NA NA NA NA NA NA NA 28029 FUN_009009 1047 1080 452 844 1140 ptg000004l:1383797-1408519 E1BYJ2 3.38e-30 DNA mismatch repair protein Msh6 Gallus gallus (Chicken) mismatch repair [GO:0006298]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of DNA endoreduplication [GO:0032876]; positive regulation of B cell proliferation [GO:0030890] GO:0003690; GO:0005524; GO:0005634; GO:0006298; GO:0007095; GO:0030890; GO:0030983; GO:0032301; GO:0032876; GO:0140664 28030 FUN_009008 406 449 106 345 199 NA NA NA NA NA NA NA 28031 FUN_015032 40 7 11 22 84 ptg000009l:5453470-5464786 Q9W7C2 9.47e-37 T-box transcription factor TBX5 (T-box protein 5) Xenopus laevis (African clawed frog) animal organ development [GO:0048513]; cell-cell signaling [GO:0007267]; embryonic forelimb morphogenesis [GO:0035115]; embryonic limb morphogenesis [GO:0030326]; heart development [GO:0007507]; negative regulation of cardiac muscle cell proliferation [GO:0060044]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; pericardium development [GO:0060039]; positive regulation of cardioblast differentiation [GO:0051891]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000978; GO:0000981; GO:0003677; GO:0003700; GO:0005634; GO:0005737; GO:0007267; GO:0007507; GO:0008285; GO:0030326; GO:0030336; GO:0032991; GO:0032993; GO:0035115; GO:0043565; GO:0045893; GO:0045944; GO:0048513; GO:0051891; GO:0060039; GO:0060044 28032 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 2.51e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28033 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 1.88e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28034 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 2.36e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28035 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 1.03e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28036 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 3.85e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28037 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 1.55e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28038 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 2.21e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28039 FUN_009003 278 65 63 121 180 ptg000004l:1319174-1325735 Q96AY4 7.99e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28040 FUN_009002 39 10 2 7 71 NA NA NA NA NA NA NA 28041 FUN_009001 56 87 13 68 77 ptg000004l:1309363-1310362 Q61184 1.17e-37 Melatonin receptor type 1A (Mel-1A-R) (Mel1a receptor) Mus musculus (Mouse) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; circadian rhythm [GO:0007623]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of insulin secretion [GO:0046676] GO:0004930; GO:0005886; GO:0007186; GO:0007193; GO:0007623; GO:0008502; GO:0042562; GO:0043025; GO:0043235; GO:0046676; GO:0097159 28042 FUN_009000 26 60 24 27 79 NA NA NA NA NA NA NA 28043 FUN_009007 312 29 70 123 88 NA NA NA NA NA NA NA 28044 FUN_009006 888 221 220 330 310 NA NA NA NA NA NA NA 28045 FUN_009005 102 338 113 116 144 NA NA NA NA NA NA NA 28046 FUN_009004 111 25 73 30 6 ptg000004l:1347064-1348078 P49286 6.09e-32 Melatonin receptor type 1B (Mel-1B-R) (Mel1b receptor) Homo sapiens (Human) camera-type eye development [GO:0043010]; chemical synaptic transmission [GO:0007268]; G protein-coupled receptor signaling pathway [GO:0007186]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; glucose homeostasis [GO:0042593]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of cytosolic calcium ion concentration [GO:0051481]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of transmission of nerve impulse [GO:0051970]; negative regulation of vasoconstriction [GO:0045906]; positive regulation of circadian sleep/wake cycle, non-REM sleep [GO:0046010]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of insulin secretion [GO:0050796]; regulation of neuronal action potential [GO:0098908] GO:0004930; GO:0005886; GO:0007186; GO:0007187; GO:0007268; GO:0008502; GO:0010754; GO:0042593; GO:0043010; GO:0043524; GO:0045202; GO:0045906; GO:0046010; GO:0046676; GO:0050796; GO:0051481; GO:0051970; GO:0051971; GO:0098908; GO:1902260 28047 FUN_010599 122 64 0 109 57 NA NA NA NA NA NA NA 28048 FUN_010598 53 77 0 154 44 NA NA NA NA NA NA NA 28049 FUN_015030 238 179 99 164 165 NA NA NA NA NA NA NA 28050 FUN_022158 0 0 30 15 0 ptg000016l:5827404-5832235 B8UU78 2.27e-153 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28051 FUN_022158 0 0 30 15 0 ptg000016l:5827404-5832235 B8UU78 2.44e-27 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28052 FUN_022157 281 149 243 339 285 ptg000016l:5814895-5820830 B8UU78 1.41e-107 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28053 FUN_022157 281 149 243 339 285 ptg000016l:5814895-5820830 B8UU78 3.84e-80 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28054 FUN_022157 281 149 243 339 285 ptg000016l:5814895-5820830 B8UU78 5.64e-26 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28055 FUN_022151 0 17 51 0 0 ptg000016l:5808315-5812333 B8UU78 1.88e-162 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28056 FUN_022151 0 17 51 0 0 ptg000016l:5808315-5812333 B8UU78 7e-25 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 28057 FUN_040673 772 414 448 1069 983 NA NA NA NA NA NA NA 28058 FUN_040672 367 285 194 225 182 NA NA NA NA NA NA NA 28059 FUN_040671 841 1067 614 896 561 NA NA NA NA NA NA NA 28060 FUN_040676 492 931 474 201 146 ptg000031l:11756147-11758842 Q9V9W8 3.61e-22 Protein pygopus (Protein gammy legs) Drosophila melanogaster (Fruit fly) canonical Wnt signaling pathway [GO:0060070]; chitin-based larval cuticle pattern formation [GO:0035293]; delamination [GO:0060232]; embryonic pattern specification [GO:0009880]; eye-antennal disc development [GO:0035214]; imaginal disc-derived wing expansion [GO:0048526]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; segment polarity determination [GO:0007367]; wing disc morphogenesis [GO:0007472] GO:0003713; GO:0005634; GO:0005654; GO:0006357; GO:0007367; GO:0007472; GO:0009880; GO:0035064; GO:0035214; GO:0035293; GO:0045944; GO:0046872; GO:0048526; GO:0060070; GO:0060232; GO:1990907 28061 FUN_040675 2041 1419 1456 2154 2036 NA NA NA NA NA NA NA 28062 FUN_040678 6 0 0 0 0 NA NA NA NA NA NA NA 28063 FUN_012986 0 0 0 11 0 NA NA NA NA NA NA NA 28064 FUN_012987 27 10 24 0 17 NA NA NA NA NA NA NA 28065 FUN_012982 0 0 0 63 121 NA NA NA NA NA NA NA 28066 FUN_012983 2780 432 44 6475 3130 NA NA NA NA NA NA NA 28067 FUN_014748 9876 7709 3814 6020 4125 NA NA NA NA NA NA NA 28068 FUN_026098 70 110 41 334 50 NA NA NA NA NA NA NA 28069 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 6.08e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28070 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 8.22e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28071 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 2.6e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28072 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 2.76e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28073 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 4.69e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28074 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 2.23e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28075 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 4.05e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28076 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 5.06e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28077 FUN_009911 132 78 89 63 115 ptg000004l:13082726-13093422 Q80XJ3 7.59e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 28078 FUN_009913 0 52 0 0 53 ptg000004l:13103412-13108214 P21328 1.17e-29 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 28079 FUN_009915 0 0 0 0 12 NA NA NA NA NA NA NA 28080 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 4.85e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28081 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 4.14e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28082 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 7.39e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28083 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 1.46e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28084 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 2.26e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28085 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 3.77e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28086 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 1.74e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28087 FUN_009914 418 654 156 219 322 ptg000004l:13112001-13116006 Q96AY4 7.72e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28088 FUN_009917 442 312 1106 208 277 NA NA NA NA NA NA NA 28089 FUN_009916 49 1 6 4 0 NA NA NA NA NA NA NA 28090 FUN_033590 0 0 0 0 22 NA NA NA NA NA NA NA 28091 FUN_014742 2928 2446 944 2406 1271 NA NA NA NA NA NA NA 28092 FUN_024419 528 165 199 337 447 ptg000018l:6064644-6081038 Q1RLU8 1.42e-21 Suppressor of tumorigenicity 7 protein homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0016020 28093 FUN_024418 119 199 85 134 111 ptg000018l:6048036-6053180 Q2QLB6 1.77e-47 Protein Wnt-2 Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch) Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055 28094 FUN_024418 119 199 85 134 111 ptg000018l:6048036-6053180 Q2QLB6 1.06e-26 Protein Wnt-2 Plecturocebus moloch (Dusky titi monkey) (Callicebus moloch) Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055 28095 FUN_024415 1363 2127 600 386 506 ptg000018l:6013714-6017586 A0A3G9HPE6 1.35e-40 Dehydrogenase ALT3 (EC 1.14.11.-) (AAL-toxin biosynthesis cluster protein 3) Alternaria alternata (Alternaria rot fungus) (Torula alternata) NA GO:0016491; GO:0046872 28096 FUN_024414 2943 3170 1613 2344 1834 ptg000018l:6008058-6012892 O18404 1.12e-31 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51, EC 1.1.1.62) (3-hydroxyacyl-CoA dehydrogenase type II) (Hydroxysteroid dehydrogenase) (EC 1.1.1.-, EC 1.1.1.53) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Scully protein) (Type II HADH) Drosophila melanogaster (Fruit fly) acyl-CoA metabolic process [GO:0006637]; androgen metabolic process [GO:0008209]; ecdysone metabolic process [GO:0008205]; estrogen metabolic process [GO:0008210]; fatty acid metabolic process [GO:0006631]; mitochondrial tRNA processing [GO:0090646]; steroid metabolic process [GO:0008202] GO:0003857; GO:0004303; GO:0005739; GO:0006631; GO:0006637; GO:0008202; GO:0008205; GO:0008209; GO:0008210; GO:0016229; GO:0018454; GO:0030678; GO:0035410; GO:0044594; GO:0047015; GO:0047022; GO:0047035; GO:0090646; GO:0106282; GO:0106283 28097 FUN_024417 3686 5777 2820 5336 4601 ptg000018l:6036353-6046591 Q06443 3.84e-36 Protein Wnt-5b Ambystoma mexicanum (Axolotl) muscle cell differentiation [GO:0042692]; positive regulation of cell migration [GO:0030335]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055; GO:0030335; GO:0042692; GO:1904105; GO:2000052 28098 FUN_024416 897 557 658 743 915 NA NA NA NA NA NA NA 28099 FUN_024411 2195 1151 1053 2733 2863 ptg000018l:5947225-5972211 Q7T163 4.23e-98 Kinase D-interacting substrate of 220 kDa B (Ankyrin repeat-rich membrane-spanning protein B) Danio rerio (Zebrafish) (Brachydanio rerio) nervous system development [GO:0007399] GO:0005770; GO:0007399; GO:0019887; GO:0030165; GO:0031902 28100 FUN_014740 254 237 244 271 291 NA NA NA NA NA NA NA 28101 FUN_024413 6565 3806 3856 6532 3686 NA NA NA NA NA NA NA 28102 FUN_024412 2142 1523 1444 2067 1642 NA NA NA NA NA NA NA 28103 FUN_014741 367 280 256 258 130 NA NA NA NA NA NA NA 28104 FUN_038739 426 97 201 200 205 NA NA NA NA NA NA NA 28105 FUN_038738 4502 2954 1366 3608 5012 ptg000027l:10786566-10792004 Q8CFY5 2.85e-22 Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.141) (Heme O synthase) Mus musculus (Mouse) aerobic respiration [GO:0009060]; cytochrome complex assembly [GO:0017004]; heme A biosynthetic process [GO:0006784]; heme biosynthetic process [GO:0006783]; lipid metabolic process [GO:0006629]; mitochondrial fission [GO:0000266]; mitochondrion organization [GO:0007005]; protein farnesylation [GO:0018343]; respiratory chain complex IV assembly [GO:0008535] GO:0000266; GO:0004311; GO:0005730; GO:0005739; GO:0005829; GO:0006629; GO:0006783; GO:0006784; GO:0007005; GO:0008495; GO:0008535; GO:0009060; GO:0017004; GO:0018343; GO:0031966; GO:0070069 28106 FUN_038735 887 715 691 1142 652 NA NA NA NA NA NA NA 28107 FUN_038734 3586 2326 1528 2402 1773 ptg000027l:10742022-10755961 Q8TB22 3.98e-23 Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0005576; GO:0005975; GO:0007283; GO:0030154 28108 FUN_038737 1983 2127 1721 1147 769 NA NA NA NA NA NA NA 28109 FUN_038736 37 41 61 7 50 NA NA NA NA NA NA NA 28110 FUN_038731 293 190 92 302 147 NA NA NA NA NA NA NA 28111 FUN_038730 60 24 22 26 43 NA NA NA NA NA NA NA 28112 FUN_038733 2801 1813 1376 2633 2053 NA NA NA NA NA NA NA 28113 FUN_038732 5049 4180 1644 4675 4011 ptg000027l:10716630-10717227 P10922 2.07e-21 Histone H1.0 (Histone H1') (Histone H1(0)) (MyD196) [Cleaved into: Histone H1.0, N-terminally processed] Mus musculus (Mouse) chromosome condensation [GO:0030261]; heterochromatin formation [GO:0031507]; negative regulation of DNA recombination [GO:0045910]; nucleosome assembly [GO:0006334]; positive regulation of transcription regulatory region DNA binding [GO:2000679] GO:0000785; GO:0000786; GO:0000791; GO:0003677; GO:0003680; GO:0003690; GO:0005634; GO:0005654; GO:0005794; GO:0006334; GO:0015629; GO:0016604; GO:0017053; GO:0030261; GO:0030527; GO:0031490; GO:0031492; GO:0031507; GO:0045910; GO:2000679 28114 FUN_028943 146 161 168 106 231 NA NA NA NA NA NA NA 28115 FUN_028941 7205 7150 4187 4317 3666 NA NA NA NA NA NA NA 28116 FUN_015063 5529 6279 2052 5700 3820 NA NA NA NA NA NA NA 28117 FUN_028947 380 404 120 486 55 ptg000022l:6277792-6279505 Q9TTT5 2.08e-66 Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3) Oryctolagus cuniculus (Rabbit) protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0008076; GO:0030425; GO:0034765; GO:0042383; GO:0046872; GO:0051260 28118 FUN_028946 1084 2275 1589 3199 1541 NA NA NA NA NA NA NA 28119 FUN_028945 139 270 123 830 392 NA NA NA NA NA NA NA 28120 FUN_028944 21 61 50 55 26 NA NA NA NA NA NA NA 28121 FUN_015068 7299 6618 2952 5944 2844 ptg000009l:5737027-5740833 Q969V4 6.81e-34 Tektin-1 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] GO:0005634; GO:0005879; GO:0015630; GO:0031514; GO:0060271; GO:0060294 28122 FUN_015068 7299 6618 2952 5944 2844 ptg000009l:5737027-5740833 Q969V4 6.06e-31 Tektin-1 Homo sapiens (Human) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] GO:0005634; GO:0005879; GO:0015630; GO:0031514; GO:0060271; GO:0060294 28123 FUN_015069 1251 924 518 1183 830 NA NA NA NA NA NA NA 28124 FUN_028949 3 5 6 7 3 NA NA NA NA NA NA NA 28125 FUN_028948 16 25 4 20 34 NA NA NA NA NA NA NA 28126 FUN_013094 74 550 284 154 92 NA NA NA NA NA NA NA 28127 FUN_028750 0 0 0 0 9 NA NA NA NA NA NA NA 28128 FUN_013090 243 728 158 421 164 ptg000008l:19401805-19489101 Q09575 6.11e-48 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 28129 FUN_013090 243 728 158 421 164 ptg000008l:19401805-19489101 Q09575 1.46e-37 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 28130 FUN_034031 17 0 4 11 9 NA NA NA NA NA NA NA 28131 FUN_034036 6132 4175 3257 6196 16789 NA NA NA NA NA NA NA 28132 FUN_014919 3007 3395 4437 5265 3113 NA NA NA NA NA NA NA 28133 FUN_014918 638 1032 368 687 572 NA NA NA NA NA NA NA 28134 FUN_014917 12 101 42 46 0 NA NA NA NA NA NA NA 28135 FUN_014916 48230 26490 27262 51421 46903 NA NA NA NA NA NA NA 28136 FUN_014915 268 206 185 354 221 NA NA NA NA NA NA NA 28137 FUN_014914 669 425 338 590 443 NA NA NA NA NA NA NA 28138 FUN_014913 93 136 41 60 36 NA NA NA NA NA NA NA 28139 FUN_014912 207 136 104 299 104 NA NA NA NA NA NA NA 28140 FUN_014911 22 0 36 41 36 NA NA NA NA NA NA NA 28141 FUN_014910 12 0 34 38 30 NA NA NA NA NA NA NA 28142 FUN_034037 0 0 132 579 201 NA NA NA NA NA NA NA 28143 FUN_039066 0 0 0 0 7 NA NA NA NA NA NA NA 28144 FUN_039067 0 0 0 0 9 NA NA NA NA NA NA NA 28145 FUN_039065 0 0 0 0 24 NA NA NA NA NA NA NA 28146 FUN_039068 0 0 3 0 42 NA NA NA NA NA NA NA 28147 FUN_043017 0 0 127 7 112 NA NA NA NA NA NA NA 28148 FUN_019613 0 0 0 0 15 NA NA NA NA NA NA NA 28149 FUN_043014 534 475 631 612 456 ptg000047l:2984368-2991715 Q91VE0 9.66e-53 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 28150 FUN_043014 534 475 631 612 456 ptg000047l:2984368-2991715 Q91VE0 4.63e-33 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 28151 FUN_043014 534 475 631 612 456 ptg000047l:2984368-2991715 Q91VE0 3.67e-24 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 28152 FUN_022978 1288 520 722 960 1142 NA NA NA NA NA NA NA 28153 FUN_022979 660 482 308 765 687 NA NA NA NA NA NA NA 28154 FUN_022970 4685 3580 2449 2717 2329 NA NA NA NA NA NA NA 28155 FUN_022971 935 933 922 855 559 NA NA NA NA NA NA NA 28156 FUN_022974 121 146 63 112 155 NA NA NA NA NA NA NA 28157 FUN_022975 4904 5787 3488 3939 3057 NA NA NA NA NA NA NA 28158 FUN_022976 948 899 1111 935 584 NA NA NA NA NA NA NA 28159 FUN_022977 0 8 0 10 0 NA NA NA NA NA NA NA 28160 FUN_027337 0 0 2 3 15 NA NA NA NA NA NA NA 28161 FUN_014433 245 160 311 30 299 NA NA NA NA NA NA NA 28162 FUN_013321 335 534 5 90 1793 NA NA NA NA NA NA NA 28163 FUN_042645 554 535 317 516 513 NA NA NA NA NA NA NA 28164 FUN_044358 231 37 98 228 1029 NA NA NA NA NA NA NA 28165 FUN_018575 0 0 6 0 5 NA NA NA NA NA NA NA 28166 FUN_044359 154 16 22 149 0 NA NA NA NA NA NA NA 28167 FUN_019404 0 0 33 24 46 NA NA NA NA NA NA NA 28168 FUN_019405 0 0 0 0 20 NA NA NA NA NA NA NA 28169 FUN_044354 52 2 82 114 500 NA NA NA NA NA NA NA 28170 FUN_044355 22 0 11 4 68 NA NA NA NA NA NA NA 28171 FUN_038899 150 0 0 0 49 NA NA NA NA NA NA NA 28172 FUN_019409 3 41 177 163 226 NA NA NA NA NA NA NA 28173 FUN_038890 232 195 239 211 71 NA NA NA NA NA NA NA 28174 FUN_038891 6845 2581 2809 6749 5792 NA NA NA NA NA NA NA 28175 FUN_038892 18120 27479 10645 15157 12380 NA NA NA NA NA NA NA 28176 FUN_038893 213 229 153 409 164 NA NA NA NA NA NA NA 28177 FUN_038894 2910 1503 272 764 2971 NA NA NA NA NA NA NA 28178 FUN_030081 0 10 0 6 21 NA NA NA NA NA NA NA 28179 FUN_027803 5871 6406 3798 5572 3743 NA NA NA NA NA NA NA 28180 FUN_018026 1161 540 474 811 1019 NA NA NA NA NA NA NA 28181 FUN_027801 120 84 0 0 99 NA NA NA NA NA NA NA 28182 FUN_018024 43 0 16 41 52 NA NA NA NA NA NA NA 28183 FUN_018023 8735 5672 3211 6921 5692 NA NA NA NA NA NA NA 28184 FUN_027806 4191 9863 5114 7334 4633 NA NA NA NA NA NA NA 28185 FUN_027805 1928 1300 696 1368 774 NA NA NA NA NA NA NA 28186 FUN_027804 30825 99275 43040 51223 28329 ptg000021l:11020181-11022982 Q9U9L2 1.37e-59 60S ribosomal protein L8 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0019843; GO:0022625 28187 FUN_027804 30825 99275 43040 51223 28329 ptg000021l:11020181-11022982 Q9U9L2 1.73e-42 60S ribosomal protein L8 Anopheles gambiae (African malaria mosquito) cytoplasmic translation [GO:0002181] GO:0002181; GO:0003723; GO:0003735; GO:0019843; GO:0022625 28188 FUN_027809 0 0 0 17 0 NA NA NA NA NA NA NA 28189 FUN_027808 7457 5286 2919 5322 3598 ptg000021l:11054405-11073930 Q9VEN1 3.43e-37 Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Filamin-1) (Filamin1) Drosophila melanogaster (Fruit fly) actin crosslink formation [GO:0051764]; behavioral response to ethanol [GO:0048149]; cytoplasmic transport, nurse cell to oocyte [GO:0007303]; determination of adult lifespan [GO:0008340]; female germline ring canal formation [GO:0007301]; female germline ring canal formation, actin assembly [GO:0008302]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; germline ring canal formation [GO:0030725]; long-term memory [GO:0007616]; mitotic cell cycle [GO:0000278]; motor neuron axon guidance [GO:0008045]; negative regulation of lamellocyte differentiation [GO:0035204]; positive regulation of cytoskeleton organization [GO:0051495]; protein localization [GO:0008104]; sarcomere organization [GO:0045214]; syncytial embryo cellularization [GO:0110069] GO:0000278; GO:0003779; GO:0005829; GO:0005886; GO:0007301; GO:0007303; GO:0007616; GO:0008045; GO:0008104; GO:0008302; GO:0008340; GO:0015629; GO:0030018; GO:0030708; GO:0030725; GO:0035182; GO:0035183; GO:0035204; GO:0035324; GO:0045179; GO:0045214; GO:0048149; GO:0051015; GO:0051495; GO:0051764; GO:0110069 28190 FUN_018029 4126 3005 1833 4145 3267 NA NA NA NA NA NA NA 28191 FUN_018028 173 0 53 10 21 NA NA NA NA NA NA NA 28192 FUN_041219 23 5 31 4 11 NA NA NA NA NA NA NA 28193 FUN_023366 292 134 171 104 193 ptg000017l:6718384-6722068 Q91WQ5 3.82e-25 TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta) Mus musculus (Mouse) histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; monoubiquitinated histone deubiquitination [GO:0035521]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA repair [GO:0006282]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; regulation of somatic stem cell population maintenance [GO:1904672]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000123; GO:0000124; GO:0003713; GO:0005634; GO:0006282; GO:0006355; GO:0006357; GO:0016573; GO:0016607; GO:0033276; GO:0035521; GO:0035522; GO:0036464; GO:0043484; GO:0043966; GO:0045893; GO:1904672 28194 FUN_023367 2773 1724 1490 1816 1130 ptg000017l:6723553-6730063 P17712 7.61e-42 Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D) Rattus norvegicus (Rat) calcium ion import [GO:0070509]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to glucose starvation [GO:0042149]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycolytic process [GO:0006096]; lipid homeostasis [GO:0055088]; mannose metabolic process [GO:0006013]; NADP metabolic process [GO:0006739]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin secretion [GO:0032024]; positive regulation of phosphorylation [GO:0042327]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]; response to glucose [GO:0009749]; second-messenger-mediated signaling [GO:0019932] GO:0000287; GO:0001678; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005938; GO:0005978; GO:0006002; GO:0006003; GO:0006006; GO:0006013; GO:0006096; GO:0006739; GO:0007204; GO:0008865; GO:0009749; GO:0019158; GO:0019903; GO:0019932; GO:0030141; GO:0032024; GO:0032811; GO:0032869; GO:0042149; GO:0042327; GO:0042593; GO:0043266; GO:0043531; GO:0044320; GO:0045180; GO:0045721; GO:0045725; GO:0045821; GO:0046835; GO:0050796; GO:0051156; GO:0051594; GO:0055088; GO:0070509 28195 FUN_023367 2773 1724 1490 1816 1130 ptg000017l:6723553-6730063 P17712 6.16e-21 Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D) Rattus norvegicus (Rat) calcium ion import [GO:0070509]; carbohydrate phosphorylation [GO:0046835]; cellular glucose homeostasis [GO:0001678]; cellular response to glucose starvation [GO:0042149]; cellular response to insulin stimulus [GO:0032869]; cellular response to leptin stimulus [GO:0044320]; detection of glucose [GO:0051594]; fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose 6-phosphate metabolic process [GO:0006002]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; glycogen biosynthetic process [GO:0005978]; glycolytic process [GO:0006096]; lipid homeostasis [GO:0055088]; mannose metabolic process [GO:0006013]; NADP metabolic process [GO:0006739]; negative regulation of epinephrine secretion [GO:0032811]; negative regulation of gluconeogenesis [GO:0045721]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of glycogen biosynthetic process [GO:0045725]; positive regulation of glycolytic process [GO:0045821]; positive regulation of insulin secretion [GO:0032024]; positive regulation of phosphorylation [GO:0042327]; regulation of insulin secretion [GO:0050796]; regulation of potassium ion transport [GO:0043266]; response to glucose [GO:0009749]; second-messenger-mediated signaling [GO:0019932] GO:0000287; GO:0001678; GO:0004340; GO:0004396; GO:0005524; GO:0005536; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005938; GO:0005978; GO:0006002; GO:0006003; GO:0006006; GO:0006013; GO:0006096; GO:0006739; GO:0007204; GO:0008865; GO:0009749; GO:0019158; GO:0019903; GO:0019932; GO:0030141; GO:0032024; GO:0032811; GO:0032869; GO:0042149; GO:0042327; GO:0042593; GO:0043266; GO:0043531; GO:0044320; GO:0045180; GO:0045721; GO:0045725; GO:0045821; GO:0046835; GO:0050796; GO:0051156; GO:0051594; GO:0055088; GO:0070509 28196 FUN_023364 711 417 176 754 932 NA NA NA NA NA NA NA 28197 FUN_023362 607 269 284 268 228 NA NA NA NA NA NA NA 28198 FUN_023363 485 53 27 160 158 NA NA NA NA NA NA NA 28199 FUN_023360 17 0 6 0 16 NA NA NA NA NA NA NA 28200 FUN_023361 2059 1140 641 1500 784 ptg000017l:6671734-6676309 Q9XTR8 1.49e-31 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 28201 FUN_023368 1442 1258 947 1032 665 NA NA NA NA NA NA NA 28202 FUN_023369 1303 593 555 715 982 ptg000017l:6741785-6755930 O96028 2.04e-67 Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) Homo sapiens (Human) atrial septum primum morphogenesis [GO:0003289]; atrial septum secundum morphogenesis [GO:0003290]; bone development [GO:0060348]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; histone H3-K36 methylation [GO:0010452]; histone H4-K20 methylation [GO:0034770]; membranous septum morphogenesis [GO:0003149]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of establishment of protein localization [GO:0070201] GO:0000122; GO:0000785; GO:0003149; GO:0003289; GO:0003290; GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0006325; GO:0006355; GO:0010452; GO:0018024; GO:0034770; GO:0042799; GO:0043565; GO:0046872; GO:0046975; GO:0048298; GO:0060348; GO:0070201; GO:0140954; GO:2001032 28203 FUN_023369 1303 593 555 715 982 ptg000017l:6741785-6755930 O96028 6.5e-35 Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein) Homo sapiens (Human) atrial septum primum morphogenesis [GO:0003289]; atrial septum secundum morphogenesis [GO:0003290]; bone development [GO:0060348]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; histone H3-K36 methylation [GO:0010452]; histone H4-K20 methylation [GO:0034770]; membranous septum morphogenesis [GO:0003149]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; regulation of DNA-templated transcription [GO:0006355]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of establishment of protein localization [GO:0070201] GO:0000122; GO:0000785; GO:0003149; GO:0003289; GO:0003290; GO:0003682; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006302; GO:0006325; GO:0006355; GO:0010452; GO:0018024; GO:0034770; GO:0042799; GO:0043565; GO:0046872; GO:0046975; GO:0048298; GO:0060348; GO:0070201; GO:0140954; GO:2001032 28204 FUN_025405 315 67 54 132 71 ptg000019l:2303295-2304321 Q5RAL7 1.26e-31 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047273 28205 FUN_025404 0 0 16 143 25 ptg000019l:2264157-2266186 O75752 2.11e-28 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (Beta-1,3-GalNAc-T1) (EC 2.4.1.79) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase) Homo sapiens (Human) glycosphingolipid metabolic process [GO:0006687]; oligosaccharide biosynthetic process [GO:0009312]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006687; GO:0008194; GO:0008499; GO:0009312; GO:0016757; GO:0047273 28206 FUN_025407 158 79 75 66 66 NA NA NA NA NA NA NA 28207 FUN_025406 647 233 83 279 130 ptg000019l:2315438-2316476 Q6P3P5 2.03e-32 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (EC 2.4.1.206) (Lactotriaosylceramide synthase) (Lc(3)Cer synthase) (Lc3 synthase) (UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5) (BGnT-5) (Beta-1,3-Gn-T5) (Beta-1,3-N-acetylglucosaminyltransferase 5) (Beta3Gn-T5) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0008457; GO:0047256 28208 FUN_025400 29 0 47 32 139 NA NA NA NA NA NA NA 28209 FUN_025403 234 337 118 667 234 NA NA NA NA NA NA NA 28210 FUN_025402 39 67 159 101 102 ptg000019l:2248148-2253080 Q8K2J9 3.16e-74 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 28211 FUN_025409 211 92 13 127 211 NA NA NA NA NA NA NA 28212 FUN_025408 2279 659 666 1618 579 NA NA NA NA NA NA NA 28213 FUN_010039 22 0 14 7 36 NA NA NA NA NA NA NA 28214 FUN_041214 1340 2464 829 1842 1972 NA NA NA NA NA NA NA 28215 FUN_018681 1 2 0 64 5 NA NA NA NA NA NA NA 28216 FUN_018680 75 0 47 0 0 NA NA NA NA NA NA NA 28217 FUN_018687 0 0 13 0 0 NA NA NA NA NA NA NA 28218 FUN_041215 0 4 17 0 7 NA NA NA NA NA NA NA 28219 FUN_019376 191 167 160 65 18 NA NA NA NA NA NA NA 28220 FUN_019370 0 0 0 0 11 NA NA NA NA NA NA NA 28221 FUN_019371 0 8 0 0 0 NA NA NA NA NA NA NA 28222 FUN_019372 0 0 0 8 8 NA NA NA NA NA NA NA 28223 FUN_019378 0 0 0 0 32 NA NA NA NA NA NA NA 28224 FUN_019379 19 0 8 0 39 NA NA NA NA NA NA NA 28225 FUN_039853 1834 1390 774 1472 1242 NA NA NA NA NA NA NA 28226 FUN_039852 599 342 283 501 704 ptg000031l:911947-914645 Q9Y399 6.02e-43 28S ribosomal protein S2, mitochondrial (MRP-S2) (S2mt) (Mitochondrial small ribosomal subunit protein uS2m) Homo sapiens (Human) mitochondrial ribosome assembly [GO:0061668]; mitochondrial translation [GO:0032543] GO:0003735; GO:0005739; GO:0005743; GO:0005763; GO:0032543; GO:0061668 28227 FUN_039851 3568 1735 1824 3305 2864 ptg000031l:894485-910882 Q9Y3P9 8.82e-29 Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA) Homo sapiens (Human) activation of GTPase activity [GO:0090630]; cell cycle [GO:0007049]; regulation of GTPase activity [GO:0043087] GO:0005096; GO:0005813; GO:0005829; GO:0005875; GO:0007049; GO:0015631; GO:0031267; GO:0043087; GO:0090630 28228 FUN_037373 100 84 67 44 5 NA NA NA NA NA NA NA 28229 FUN_039857 1 0 0 39 33 NA NA NA NA NA NA NA 28230 FUN_039856 138 651 134 578 292 NA NA NA NA NA NA NA 28231 FUN_039855 653 498 498 712 226 ptg000031l:959677-966671 O00370 2.8e-26 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 28232 FUN_033830 0 0 0 4 57 NA NA NA NA NA NA NA 28233 FUN_041212 1474 3898 1251 2787 1531 ptg000035l:252269-253318 P61227 4.83e-80 Ras-related protein Rap-2b (EC 3.6.5.2) Rattus norvegicus (Rat) negative regulation of cell migration [GO:0030336]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of protein autophosphorylation [GO:0031954]; Rap protein signal transduction [GO:0032486]; regulation of protein tyrosine kinase activity [GO:0061097] GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0005923; GO:0016020; GO:0019003; GO:0019904; GO:0030168; GO:0030336; GO:0031954; GO:0032486; GO:0044291; GO:0045121; GO:0055037; GO:0055038; GO:0061097; GO:0070062; GO:0070527 28234 FUN_039859 1236 1763 769 3474 2054 NA NA NA NA NA NA NA 28235 FUN_039858 966 2829 1124 3853 2962 NA NA NA NA NA NA NA 28236 FUN_033839 667 187 165 97 281 NA NA NA NA NA NA NA 28237 FUN_033838 22 0 6 16 119 NA NA NA NA NA NA NA 28238 FUN_018975 0 0 0 0 47 NA NA NA NA NA NA NA 28239 FUN_018974 11 0 2 0 49 NA NA NA NA NA NA NA 28240 FUN_024758 2554 1923 1224 2102 1259 NA NA NA NA NA NA NA 28241 FUN_018971 0 6 0 20 5 NA NA NA NA NA NA NA 28242 FUN_018970 41 7 0 50 0 NA NA NA NA NA NA NA 28243 FUN_018972 27 15 12 8 66 NA NA NA NA NA NA NA 28244 FUN_024752 1148 1138 901 1252 1399 NA NA NA NA NA NA NA 28245 FUN_024753 4319 3762 1790 3413 1993 NA NA NA NA NA NA NA 28246 FUN_024750 2342 1655 1259 3434 2216 ptg000018l:10599262-10626826 Q95SX7 9.42e-44 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 28247 FUN_024751 899 596 403 545 543 NA NA NA NA NA NA NA 28248 FUN_024756 255 342 60 227 203 ptg000018l:10674155-10675874 Q9P0M2 1.54e-27 A-kinase anchor protein 7 isoform gamma (AKAP-7 isoform gamma) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoform gamma) (PRKA7 isoform gamma) Homo sapiens (Human) modulation of chemical synaptic transmission [GO:0050804]; regulation of protein kinase A signaling [GO:0010738] GO:0000166; GO:0005634; GO:0005829; GO:0010738; GO:0019901; GO:0032991; GO:0034237; GO:0050804; GO:0051018; GO:0098686 28249 FUN_024757 1286 1258 507 1315 965 ptg000018l:10675954-10691860 Q3B8N0 1.07e-41 Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-) Xenopus laevis (African clawed frog) proteolysis [GO:0006508] GO:0005634; GO:0005737; GO:0005783; GO:0006508; GO:0071567 28250 FUN_024754 1121 1312 603 781 369 NA NA NA NA NA NA NA 28251 FUN_024755 1157 135 953 512 743 ptg000018l:10664520-10672650 P22304 7.33e-52 Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain] Homo sapiens (Human) dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0004423; GO:0005509; GO:0005737; GO:0005764; GO:0006027; GO:0008484; GO:0030200; GO:0030209; GO:0043202 28252 FUN_024755 1157 135 953 512 743 ptg000018l:10664520-10672650 P22304 6.36e-35 Iduronate 2-sulfatase (EC 3.1.6.13) (Alpha-L-iduronate sulfate sulfatase) (Idursulfase) [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain] Homo sapiens (Human) dermatan sulfate catabolic process [GO:0030209]; glycosaminoglycan catabolic process [GO:0006027]; heparan sulfate proteoglycan catabolic process [GO:0030200] GO:0004423; GO:0005509; GO:0005737; GO:0005764; GO:0006027; GO:0008484; GO:0030200; GO:0030209; GO:0043202 28253 FUN_005807 0 0 3 0 9 NA NA NA NA NA NA NA 28254 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 4.11e-40 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28255 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 4.85e-36 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28256 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 3.31e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28257 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 1.48e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28258 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 3.91e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28259 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 5.78e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28260 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 2.38e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28261 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 8.45e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28262 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 1.55e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28263 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 2.54e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28264 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 3.75e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28265 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 5.05e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28266 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 7.72e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28267 FUN_041213 1664 2473 967 3070 2110 ptg000035l:263429-270720 P10079 1.67e-24 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 28268 FUN_019084 0 0 13 11 30 NA NA NA NA NA NA NA 28269 FUN_019083 0 0 0 0 187 NA NA NA NA NA NA NA 28270 FUN_019080 0 0 0 0 26 NA NA NA NA NA NA NA 28271 FUN_019081 0 0 0 0 144 NA NA NA NA NA NA NA 28272 FUN_041210 1849 2107 707 2340 1797 NA NA NA NA NA NA NA 28273 FUN_000567 406 376 126 796 417 NA NA NA NA NA NA NA 28274 FUN_000566 94 98 46 60 342 NA NA NA NA NA NA NA 28275 FUN_000565 1234 963 308 1352 733 NA NA NA NA NA NA NA 28276 FUN_005455 2080 1742 1532 1557 777 ntLink_8:35471154-35543401 Q99315 9.57e-73 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 28277 FUN_005455 2080 1742 1532 1557 777 ntLink_8:35471154-35543401 Q99315 1.44e-53 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 28278 FUN_005455 2080 1742 1532 1557 777 ntLink_8:35471154-35543401 Q99315 1.44e-53 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 28279 FUN_005455 2080 1742 1532 1557 777 ntLink_8:35471154-35543401 Q99315 5.43e-46 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 28280 FUN_005455 2080 1742 1532 1557 777 ntLink_8:35471154-35543401 Q99315 9.02e-32 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 28281 FUN_000564 298 262 296 710 613 NA NA NA NA NA NA NA 28282 FUN_000563 1601 1163 636 1067 736 NA NA NA NA NA NA NA 28283 FUN_041536 6110 3094 2714 5418 5804 NA NA NA NA NA NA NA 28284 FUN_035295 135 85 18 119 84 NA NA NA NA NA NA NA 28285 FUN_035294 159 44 36 77 135 NA NA NA NA NA NA NA 28286 FUN_038078 1031 1367 669 941 869 NA NA NA NA NA NA NA 28287 FUN_038079 469 310 394 643 421 ptg000027l:2190918-2198859 Q3TB48 6.77e-78 Transmembrane protein 104 Mus musculus (Mouse) NA GO:0016020 28288 FUN_035291 102 28 5 24 37 NA NA NA NA NA NA NA 28289 FUN_035290 1374 550 938 660 604 NA NA NA NA NA NA NA 28290 FUN_035293 1403 633 408 808 409 ptg000025l:6115030-6116329 A0A3M6TIF0 0 NA NA NA NA 28291 FUN_035292 31 21 21 46 42 NA NA NA NA NA NA NA 28292 FUN_038072 1785 1127 889 1760 1358 NA NA NA NA NA NA NA 28293 FUN_038073 136 71 110 102 144 NA NA NA NA NA NA NA 28294 FUN_038070 319 9248 225 1200 4914 NA NA NA NA NA NA NA 28295 FUN_038071 4108 2624 2572 4648 3329 NA NA NA NA NA NA NA 28296 FUN_035299 29 138 0 55 35 ptg000025l:6159113-6161357 A0A3M6TIF0 2.53e-49 NA NA NA NA 28297 FUN_038077 1764 367 0 7 48 NA NA NA NA NA NA NA 28298 FUN_038074 2105 2478 1809 2148 2349 NA NA NA NA NA NA NA 28299 FUN_038075 210 0 0 0 55 NA NA NA NA NA NA NA 28300 FUN_036928 45 27 19 76 89 NA NA NA NA NA NA NA 28301 FUN_036929 32 42 51 32 158 NA NA NA NA NA NA NA 28302 FUN_036926 1443 1533 894 1144 837 NA NA NA NA NA NA NA 28303 FUN_036927 148 59 55 161 327 NA NA NA NA NA NA NA 28304 FUN_036924 9402 6992 4356 5918 4587 ptg000026l:3471869-3481763 Q9D6Y9 9.51e-48 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 28305 FUN_036924 9402 6992 4356 5918 4587 ptg000026l:3471869-3481763 Q9D6Y9 1.19e-40 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 28306 FUN_036924 9402 6992 4356 5918 4587 ptg000026l:3471869-3481763 Q9D6Y9 1.19e-40 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 28307 FUN_036924 9402 6992 4356 5918 4587 ptg000026l:3471869-3481763 Q9D6Y9 1.06e-26 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 28308 FUN_036924 9402 6992 4356 5918 4587 ptg000026l:3471869-3481763 Q9D6Y9 3.91e-23 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 28309 FUN_036924 9402 6992 4356 5918 4587 ptg000026l:3471869-3481763 Q9D6Y9 4.49e-21 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glycogen biosynthetic process [GO:0005978]; negative regulation of neuron apoptotic process [GO:0043524] GO:0003844; GO:0004553; GO:0005737; GO:0005829; GO:0005975; GO:0005978; GO:0030246; GO:0043169; GO:0043524; GO:0102752 28310 FUN_036925 3057 2367 1437 1905 1007 NA NA NA NA NA NA NA 28311 FUN_036922 809 645 488 730 797 NA NA NA NA NA NA NA 28312 FUN_036923 2250 1933 1255 2058 1975 ptg000026l:3444004-3469990 P20825 2.37e-81 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 28313 FUN_036920 233 210 44 190 280 ptg000026l:3397031-3399124 Q4V8B8 3.65e-79 tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase) Rattus norvegicus (Rat) tRNA methylation [GO:0030488] GO:0005737; GO:0008175; GO:0030488; GO:0102522 28314 FUN_036920 233 210 44 190 280 ptg000026l:3397031-3399124 Q4V8B8 1.74e-23 tRNA wybutosine-synthesizing protein 2 homolog (tRNA-yW-synthesizing protein 2) (EC 2.5.1.114) (tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase) Rattus norvegicus (Rat) tRNA methylation [GO:0030488] GO:0005737; GO:0008175; GO:0030488; GO:0102522 28315 FUN_036921 1502 823 1041 1295 1376 ptg000026l:3402905-3430328 Q9NBX4 6.53e-22 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 28316 FUN_036921 1502 823 1041 1295 1376 ptg000026l:3402905-3430328 Q9NBX4 6.53e-22 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 28317 FUN_036034 765 378 482 549 829 NA NA NA NA NA NA NA 28318 FUN_035749 2054 1753 684 1235 960 NA NA NA NA NA NA NA 28319 FUN_036035 209 140 252 443 345 ptg000025l:14732866-14739718 P78357 1.31e-49 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (p190) Homo sapiens (Human) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128]; signal transduction [GO:0007165] GO:0002175; GO:0005886; GO:0007005; GO:0007010; GO:0007155; GO:0007165; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030913; GO:0033010; GO:0033270; GO:0038023; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 28320 FUN_035747 587 407 406 806 972 ptg000025l:11262975-11279708 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 28321 FUN_035747 587 407 406 806 972 ptg000025l:11262975-11279708 Q9P2E3 3.32e-70 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 28322 FUN_031024 24 38 71 5 13 NA NA NA NA NA NA NA 28323 FUN_036037 83 74 86 134 13 NA NA NA NA NA NA NA 28324 FUN_017731 0 0 0 0 6 NA NA NA NA NA NA NA 28325 FUN_031023 0 0 25 0 35 NA NA NA NA NA NA NA 28326 FUN_025548 170 167 181 293 124 NA NA NA NA NA NA NA 28327 FUN_036032 468 302 140 344 372 NA NA NA NA NA NA NA 28328 FUN_001616 4197 3632 2872 3500 3792 NA NA NA NA NA NA NA 28329 FUN_001617 98 3 16 29 15 NA NA NA NA NA NA NA 28330 FUN_001614 0 0 0 0 76 ntLink_6:14309994-14315412 P17971 4.98e-75 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 28331 FUN_001615 221 98 53 294 116 NA NA NA NA NA NA NA 28332 FUN_001612 1658 1030 1002 1688 1443 ntLink_6:14294389-14304580 P91928 6.53e-40 MICOS complex subunit Mic60 Drosophila melanogaster (Fruit fly) cristae formation [GO:0042407]; mitochondrion morphogenesis [GO:0070584]; mitochondrion organization [GO:0007005] GO:0005737; GO:0005739; GO:0005743; GO:0007005; GO:0019901; GO:0042407; GO:0043008; GO:0061617; GO:0070584 28333 FUN_001613 91 20 24 48 140 NA NA NA NA NA NA NA 28334 FUN_001610 54 9 0 0 55 NA NA NA NA NA NA NA 28335 FUN_001611 2314 1502 647 1260 1255 NA NA NA NA NA NA NA 28336 FUN_001618 110 63 90 210 188 ntLink_6:14354845-14356778 Q95JJ0 2.48e-67 Protein O-mannose kinase (POMK) (EC 2.7.1.183) (Protein kinase-like protein SgK196) (Sugen kinase 196) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) carbohydrate phosphorylation [GO:0046835]; protein O-linked glycosylation [GO:0006493]; protein phosphorylation [GO:0006468] GO:0004672; GO:0005524; GO:0005789; GO:0006468; GO:0006493; GO:0016773; GO:0019200; GO:0046835 28337 FUN_001619 369 163 163 331 330 NA NA NA NA NA NA NA 28338 FUN_007334 221 128 125 212 203 ptg000002l:1449399-1451834 Q14C59 1.7e-31 Transmembrane protease serine 11B-like protein (EC 3.4.21.-) (Airway trypsin-like protease 5) (Transmembrane protease serine 11B) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0008236 28339 FUN_007330 34 0 21 0 46 NA NA NA NA NA NA NA 28340 FUN_036218 95 215 190 220 62 NA NA NA NA NA NA NA 28341 FUN_036214 25 0 21 0 0 NA NA NA NA NA NA NA 28342 FUN_036215 0 119 0 54 28 NA NA NA NA NA NA NA 28343 FUN_036216 19 293 142 332 17 ptg000025l:16689490-16690800 A0A2B4RP11 3.76e-65 NA NA NA NA 28344 FUN_036217 45 0 8 55 12 NA NA NA NA NA NA NA 28345 FUN_036210 59 258 6 140 23 ptg000025l:16578534-16587618 O54991 1.58e-35 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 28346 FUN_036211 125 0 73 87 51 NA NA NA NA NA NA NA 28347 FUN_036212 2150 2024 883 1986 1519 NA NA NA NA NA NA NA 28348 FUN_036213 6624 4490 3661 7665 5180 NA NA NA NA NA NA NA 28349 FUN_027478 0 0 9 0 0 NA NA NA NA NA NA NA 28350 FUN_027470 0 26 20 0 15 NA NA NA NA NA NA NA 28351 FUN_027471 0 65 51 0 12 NA NA NA NA NA NA NA 28352 FUN_027476 45 0 23 0 146 NA NA NA NA NA NA NA 28353 FUN_027477 0 26 0 0 0 NA NA NA NA NA NA NA 28354 FUN_027474 0 0 32 0 0 NA NA NA NA NA NA NA 28355 FUN_000057 6 0 18 2 26 ntLink_4:23360-24123 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28356 FUN_000055 6 0 18 0 19 ntLink_4:19294-20057 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28357 FUN_000053 8 0 19 1 19 ntLink_4:15228-15991 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28358 FUN_000051 8 0 16 2 16 ntLink_4:11162-11925 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28359 FUN_000059 9 0 15 1 22 ntLink_4:27426-28189 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28360 FUN_042682 4 3 32 32 139 NA NA NA NA NA NA NA 28361 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28362 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28363 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28364 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28365 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28366 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28367 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28368 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 5.41e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28369 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 2.63e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28370 FUN_033192 39 64 10 57 85 ptg000023l:40886833-40893864 Q96AY4 3.2e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28371 FUN_033194 0 0 0 7 1 NA NA NA NA NA NA NA 28372 FUN_033195 0 0 7 0 0 NA NA NA NA NA NA NA 28373 FUN_033196 0 45 6 18 4 ptg000023l:40940471-40949378 Q96AY4 7.95e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28374 FUN_033196 0 45 6 18 4 ptg000023l:40940471-40949378 Q96AY4 4.75e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28375 FUN_033196 0 45 6 18 4 ptg000023l:40940471-40949378 Q96AY4 6.62e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28376 FUN_033196 0 45 6 18 4 ptg000023l:40940471-40949378 Q96AY4 4.53e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28377 FUN_033196 0 45 6 18 4 ptg000023l:40940471-40949378 Q96AY4 5.65e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28378 FUN_033196 0 45 6 18 4 ptg000023l:40940471-40949378 Q96AY4 4.4e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28379 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28380 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 4.92e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28381 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.14e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28382 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.64e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28383 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 3.35e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28384 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 9.03e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28385 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.78e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28386 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 2.09e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28387 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 2.23e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28388 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 3.54e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28389 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 2.47e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28390 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 3.13e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28391 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 9e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28392 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.42e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28393 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.7e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28394 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.28e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28395 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 2.82e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28396 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.21e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28397 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 1.84e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28398 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 8.21e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28399 FUN_033197 0 26 1 13 2 ptg000023l:40953659-40957599 Q96AY4 9.64e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28400 FUN_033198 88 6 0 27 52 NA NA NA NA NA NA NA 28401 FUN_013324 5356 5152 4320 9632 8436 NA NA NA NA NA NA NA 28402 FUN_008221 27 4 0 19 21 NA NA NA NA NA NA NA 28403 FUN_008222 27 38 7 37 95 NA NA NA NA NA NA NA 28404 FUN_008223 3343 3120 2048 3136 2689 NA NA NA NA NA NA NA 28405 FUN_006648 119 142 130 97 221 NA NA NA NA NA NA NA 28406 FUN_006649 3974 2296 1459 2959 1974 ptg000001l:15146869-15152538 Q27888 7.01e-24 L-lactate dehydrogenase (LDH) (EC 1.1.1.27) Caenorhabditis elegans carboxylic acid metabolic process [GO:0019752] GO:0004459; GO:0005737; GO:0019752 28407 FUN_008226 607 501 177 734 576 ptg000002l:9473515-9475341 Q9JJS6 4e-36 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Mus musculus (Mouse) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0005829; GO:0010436; GO:0016121; GO:0042572; GO:0042574; GO:0046872; GO:1901810 28408 FUN_041591 1457 1138 655 1214 685 NA NA NA NA NA NA NA 28409 FUN_006644 45 32 44 36 28 NA NA NA NA NA NA NA 28410 FUN_008229 69 141 163 121 144 NA NA NA NA NA NA NA 28411 FUN_006646 779 810 419 1092 1373 NA NA NA NA NA NA NA 28412 FUN_006647 802 608 482 576 589 NA NA NA NA NA NA NA 28413 FUN_006640 1374 1639 836 1250 486 NA NA NA NA NA NA NA 28414 FUN_006641 142 159 56 222 123 NA NA NA NA NA NA NA 28415 FUN_006642 9215 6472 2838 5663 3640 ptg000001l:15073546-15083635 P60924 4.11e-30 DAP3-binding cell death enhancer 1 (DAP3-binding cell death enhancer 1, long form) (DELE1(L)) (Death ligand signal enhancer) [Cleaved into: DAP3-binding cell death enhancer 1 short form (DELE1(S)) (S-DELE1)] Rattus norvegicus (Rat) extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281] GO:0005739; GO:0005743; GO:0005829; GO:0008625; GO:0043281; GO:0043539; GO:0140467; GO:0140468 28416 FUN_006642 9215 6472 2838 5663 3640 ptg000001l:15073546-15083635 P60924 4.01e-27 DAP3-binding cell death enhancer 1 (DAP3-binding cell death enhancer 1, long form) (DELE1(L)) (Death ligand signal enhancer) [Cleaved into: DAP3-binding cell death enhancer 1 short form (DELE1(S)) (S-DELE1)] Rattus norvegicus (Rat) extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; HRI-mediated signaling [GO:0140468]; integrated stress response signaling [GO:0140467]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281] GO:0005739; GO:0005743; GO:0005829; GO:0008625; GO:0043281; GO:0043539; GO:0140467; GO:0140468 28417 FUN_006643 1955 2180 1608 1911 1165 NA NA NA NA NA NA NA 28418 FUN_016663 0 0 18 0 20 NA NA NA NA NA NA NA 28419 FUN_016688 377 8 330 307 454 ptg000011l:6295145-6299133 A2RUC4 5.45e-31 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 28420 FUN_016688 377 8 330 307 454 ptg000011l:6295145-6299133 A2RUC4 5.13e-22 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 28421 FUN_016685 4 0 11 88 0 NA NA NA NA NA NA NA 28422 FUN_016684 178 0 216 404 220 NA NA NA NA NA NA NA 28423 FUN_016687 59 0 28 50 98 ptg000011l:6286117-6291452 Q06496 8.86e-57 Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1) Rattus norvegicus (Rat) arsenate ion transmembrane transport [GO:1901684]; bone remodeling [GO:0046849]; calcium ion homeostasis [GO:0055074]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to metal ion [GO:0071248]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to phosphate starvation [GO:0016036]; cellular response to staurosporine [GO:0072734]; dentinogenesis [GO:0097187]; gene expression [GO:0010467]; gentamycin metabolic process [GO:1901128]; glycoprotein metabolic process [GO:0009100]; indole metabolic process [GO:0042431]; inorganic diphosphate transport [GO:0030505]; kidney development [GO:0001822]; ossification [GO:0001503]; phosphate ion homeostasis [GO:0055062]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; positive regulation of membrane potential [GO:0045838]; positive regulation of phosphate transmembrane transport [GO:2000187]; positive regulation of sodium-dependent phosphate transport [GO:2000120]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to growth hormone [GO:0060416]; response to lead ion [GO:0010288]; response to magnesium ion [GO:0032026]; response to mercury ion [GO:0046689]; response to nutrient [GO:0007584]; response to parathyroid hormone [GO:0071107]; response to peptide [GO:1901652]; response to peptide hormone [GO:0043434]; response to potassium ion [GO:0035864]; response to sodium phosphate [GO:1904383]; response to thyroid hormone [GO:0097066]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; sodium ion import across plasma membrane [GO:0098719]; sodium-dependent phosphate transport [GO:0044341]; tricarboxylic acid metabolic process [GO:0072350] GO:0001503; GO:0001822; GO:0005436; GO:0005768; GO:0005829; GO:0005886; GO:0005903; GO:0006817; GO:0007584; GO:0009100; GO:0009410; GO:0009986; GO:0010288; GO:0010467; GO:0016036; GO:0016323; GO:0016324; GO:0016607; GO:0030165; GO:0030505; GO:0030643; GO:0031526; GO:0031982; GO:0032026; GO:0032355; GO:0033189; GO:0035435; GO:0035864; GO:0042431; GO:0042802; GO:0043434; GO:0044341; GO:0044877; GO:0045121; GO:0045838; GO:0046686; GO:0046689; GO:0046849; GO:0048471; GO:0055062; GO:0055074; GO:0060416; GO:0071107; GO:0071248; GO:0071374; GO:0072350; GO:0072686; GO:0072734; GO:0097066; GO:0097187; GO:0098719; GO:1901128; GO:1901652; GO:1901684; GO:1904383; GO:2000120; GO:2000187 28424 FUN_016686 199 21 228 255 204 ptg000011l:6283610-6285214 A2RUC4 1.77e-31 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 28425 FUN_016686 199 21 228 255 204 ptg000011l:6283610-6285214 A2RUC4 2.02e-22 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 28426 FUN_016681 148 3 105 85 145 ptg000011l:6238923-6243643 Q28620 1.42e-46 Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (NaPi-6) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1) Oryctolagus cuniculus (Rabbit) cellular response to phosphate starvation [GO:0016036]; phosphate ion homeostasis [GO:0055062]; phosphate ion transport [GO:0006817]; sodium-dependent phosphate transport [GO:0044341] GO:0005436; GO:0005886; GO:0006817; GO:0016036; GO:0016324; GO:0044341; GO:0055062 28427 FUN_016680 299 0 187 268 88 NA NA NA NA NA NA NA 28428 FUN_016683 9 0 46 0 114 ptg000011l:6259835-6268309 Q06496 2e-63 Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1) Rattus norvegicus (Rat) arsenate ion transmembrane transport [GO:1901684]; bone remodeling [GO:0046849]; calcium ion homeostasis [GO:0055074]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to metal ion [GO:0071248]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to phosphate starvation [GO:0016036]; cellular response to staurosporine [GO:0072734]; dentinogenesis [GO:0097187]; gene expression [GO:0010467]; gentamycin metabolic process [GO:1901128]; glycoprotein metabolic process [GO:0009100]; indole metabolic process [GO:0042431]; inorganic diphosphate transport [GO:0030505]; kidney development [GO:0001822]; ossification [GO:0001503]; phosphate ion homeostasis [GO:0055062]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; positive regulation of membrane potential [GO:0045838]; positive regulation of phosphate transmembrane transport [GO:2000187]; positive regulation of sodium-dependent phosphate transport [GO:2000120]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to growth hormone [GO:0060416]; response to lead ion [GO:0010288]; response to magnesium ion [GO:0032026]; response to mercury ion [GO:0046689]; response to nutrient [GO:0007584]; response to parathyroid hormone [GO:0071107]; response to peptide [GO:1901652]; response to peptide hormone [GO:0043434]; response to potassium ion [GO:0035864]; response to sodium phosphate [GO:1904383]; response to thyroid hormone [GO:0097066]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; sodium ion import across plasma membrane [GO:0098719]; sodium-dependent phosphate transport [GO:0044341]; tricarboxylic acid metabolic process [GO:0072350] GO:0001503; GO:0001822; GO:0005436; GO:0005768; GO:0005829; GO:0005886; GO:0005903; GO:0006817; GO:0007584; GO:0009100; GO:0009410; GO:0009986; GO:0010288; GO:0010467; GO:0016036; GO:0016323; GO:0016324; GO:0016607; GO:0030165; GO:0030505; GO:0030643; GO:0031526; GO:0031982; GO:0032026; GO:0032355; GO:0033189; GO:0035435; GO:0035864; GO:0042431; GO:0042802; GO:0043434; GO:0044341; GO:0044877; GO:0045121; GO:0045838; GO:0046686; GO:0046689; GO:0046849; GO:0048471; GO:0055062; GO:0055074; GO:0060416; GO:0071107; GO:0071248; GO:0071374; GO:0072350; GO:0072686; GO:0072734; GO:0097066; GO:0097187; GO:0098719; GO:1901128; GO:1901652; GO:1901684; GO:1904383; GO:2000120; GO:2000187 28429 FUN_016682 178 15 164 149 162 ptg000011l:6251808-6255806 A2RUC4 5.47e-31 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 28430 FUN_016682 178 15 164 149 162 ptg000011l:6251808-6255806 A2RUC4 8.79e-22 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 28431 FUN_010211 22 0 0 59 43 NA NA NA NA NA NA NA 28432 FUN_004734 415 338 360 36 38 NA NA NA NA NA NA NA 28433 FUN_003508 58 5 85 7 217 NA NA NA NA NA NA NA 28434 FUN_003509 0 0 13 0 0 NA NA NA NA NA NA NA 28435 FUN_004738 166 120 78 90 176 NA NA NA NA NA NA NA 28436 FUN_004739 1031 953 460 495 295 ntLink_8:26396338-26400230 Q0VCL9 2.92e-26 Uncharacterized protein C3orf38 homolog Bos taurus (Bovine) apoptotic process [GO:0006915] GO:0006915 28437 FUN_016665 307 11 3 0 188 NA NA NA NA NA NA NA 28438 FUN_016664 776 153 912 1356 655 NA NA NA NA NA NA NA 28439 FUN_041593 641 238 437 470 267 NA NA NA NA NA NA NA 28440 FUN_032829 37 21 23 36 43 NA NA NA NA NA NA NA 28441 FUN_032828 21 32 12 36 13 NA NA NA NA NA NA NA 28442 FUN_032827 0 14 0 3 0 NA NA NA NA NA NA NA 28443 FUN_032826 1476 1328 141 1664 1700 NA NA NA NA NA NA NA 28444 FUN_032825 759 1094 667 1241 688 NA NA NA NA NA NA NA 28445 FUN_032823 123 51 55 102 77 NA NA NA NA NA NA NA 28446 FUN_032822 0 0 0 24 57 NA NA NA NA NA NA NA 28447 FUN_042948 0 0 0 0 34 NA NA NA NA NA NA NA 28448 FUN_041889 4718 3024 1784 3184 3146 NA NA NA NA NA NA NA 28449 FUN_041888 8385 8184 4823 8007 7053 NA NA NA NA NA NA NA 28450 FUN_041886 964 531 380 903 794 NA NA NA NA NA NA NA 28451 FUN_041885 651 413 295 396 368 NA NA NA NA NA NA NA 28452 FUN_041884 1139 761 868 1054 1195 NA NA NA NA NA NA NA 28453 FUN_041883 163 41 66 105 74 ptg000035l:8565188-8566454 Q8N6U8 7.51e-31 G-protein coupled receptor 161 (G-protein coupled receptor RE2) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007186; GO:0007189; GO:0030666; GO:0043005; GO:0055037; GO:0060170; GO:0097386; GO:1901621 28454 FUN_041882 556 938 391 1179 498 NA NA NA NA NA NA NA 28455 FUN_041881 834 1620 1636 2232 560 NA NA NA NA NA NA NA 28456 FUN_041880 492 498 304 688 222 NA NA NA NA NA NA NA 28457 FUN_010014 19 14 5 7 11 NA NA NA NA NA NA NA 28458 FUN_011160 0 0 0 0 7 NA NA NA NA NA NA NA 28459 FUN_011164 0 0 0 0 7 ptg000007l:6965229-6975525 P14381 7.75e-27 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 28460 FUN_011167 0 3 1 1 31 NA NA NA NA NA NA NA 28461 FUN_011168 0 2 5 0 67 NA NA NA NA NA NA NA 28462 FUN_024777 1197 595 801 665 858 NA NA NA NA NA NA NA 28463 FUN_000599 487 724 133 328 158 NA NA NA NA NA NA NA 28464 FUN_040826 0 0 0 0 12 NA NA NA NA NA NA NA 28465 FUN_040824 0 0 0 0 13 NA NA NA NA NA NA NA 28466 FUN_040822 0 0 0 12 0 NA NA NA NA NA NA NA 28467 FUN_040823 0 0 0 9 0 NA NA NA NA NA NA NA 28468 FUN_040820 0 0 0 14 0 NA NA NA NA NA NA NA 28469 FUN_040821 0 0 0 0 21 NA NA NA NA NA NA NA 28470 FUN_040828 23 0 0 0 0 NA NA NA NA NA NA NA 28471 FUN_040829 30 24 115 0 159 NA NA NA NA NA NA NA 28472 FUN_010018 1367 1200 262 413 731 NA NA NA NA NA NA NA 28473 FUN_002369 0 0 70 0 0 NA NA NA NA NA NA NA 28474 FUN_002368 0 1 25 1 4 NA NA NA NA NA NA NA 28475 FUN_002367 0 0 56 0 0 NA NA NA NA NA NA NA 28476 FUN_002366 70 0 34 0 0 NA NA NA NA NA NA NA 28477 FUN_002365 492 0 243 37 20 NA NA NA NA NA NA NA 28478 FUN_002364 1150 0 624 3 0 NA NA NA NA NA NA NA 28479 FUN_002363 0 0 20 52 76 NA NA NA NA NA NA NA 28480 FUN_002362 303 263 260 471 239 NA NA NA NA NA NA NA 28481 FUN_002360 0 9 0 11 0 NA NA NA NA NA NA NA 28482 FUN_023444 1430 1081 834 817 709 NA NA NA NA NA NA NA 28483 FUN_000884 6 181 7 39 5 NA NA NA NA NA NA NA 28484 FUN_000885 13 0 0 0 0 NA NA NA NA NA NA NA 28485 FUN_000886 7 0 0 0 3 NA NA NA NA NA NA NA 28486 FUN_029402 9807 6571 4881 6819 2595 ptg000023l:1541314-1541626 Q6LAF1 1.14e-52 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28487 FUN_000880 135 225 36 42 162 NA NA NA NA NA NA NA 28488 FUN_000881 0 18 0 0 40 NA NA NA NA NA NA NA 28489 FUN_000882 4 9 8 0 23 NA NA NA NA NA NA NA 28490 FUN_000883 453 512 223 366 657 NA NA NA NA NA NA NA 28491 FUN_000888 64 79 71 89 115 NA NA NA NA NA NA NA 28492 FUN_000889 1181 585 148 514 296 NA NA NA NA NA NA NA 28493 FUN_016308 3809 4936 1765 1723 1278 NA NA NA NA NA NA NA 28494 FUN_016309 722 478 428 426 482 NA NA NA NA NA NA NA 28495 FUN_026191 881 521 123 474 516 NA NA NA NA NA NA NA 28496 FUN_028376 174 680 225 291 494 NA NA NA NA NA NA NA 28497 FUN_016300 180 34 25 66 16 NA NA NA NA NA NA NA 28498 FUN_016301 3235 2068 1478 3016 2177 NA NA NA NA NA NA NA 28499 FUN_016302 234 78 104 316 168 ptg000011l:1329015-1330500 Q9UIU6 1.52e-85 Homeobox protein SIX4 (Sine oculis homeobox homolog 4) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; embryonic cranial skeleton morphogenesis [GO:0048701]; fungiform papilla morphogenesis [GO:0061197]; generation of neurons [GO:0048699]; inner ear morphogenesis [GO:0042472]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; male sex differentiation [GO:0046661]; metanephric mesenchyme development [GO:0072075]; myoblast migration [GO:0051451]; myotome development [GO:0061055]; negative regulation of apoptotic process [GO:0043066]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of satellite cell differentiation [GO:1902725]; olfactory placode formation [GO:0030910]; pharyngeal system development [GO:0060037]; positive regulation of branching involved in ureteric bud morphogenesis [GO:0090190]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of ureteric bud formation [GO:0072107]; protein localization to nucleus [GO:0034504]; regulation of branch elongation involved in ureteric bud branching [GO:0072095]; regulation of epithelial cell proliferation [GO:0050678]; regulation of protein localization [GO:0032880]; regulation of synaptic assembly at neuromuscular junction [GO:0008582]; regulation of transcription by RNA polymerase II [GO:0006357]; sarcomere organization [GO:0045214]; skeletal muscle fiber differentiation [GO:0098528]; skeletal muscle tissue development [GO:0007519]; thymus development [GO:0048538]; tongue development [GO:0043586]; trigeminal ganglion development [GO:0061551] GO:0000785; GO:0000978; GO:0000981; GO:0001228; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0007519; GO:0008582; GO:0008584; GO:0009653; GO:0030238; GO:0030910; GO:0032880; GO:0034504; GO:0042472; GO:0043066; GO:0043524; GO:0043586; GO:0045214; GO:0045892; GO:0045893; GO:0046661; GO:0048538; GO:0048699; GO:0048701; GO:0050678; GO:0051451; GO:0060037; GO:0061055; GO:0061197; GO:0061551; GO:0072075; GO:0072095; GO:0072107; GO:0090190; GO:0098528; GO:1902725; GO:1990837 28500 FUN_016303 12 2 18 0 99 NA NA NA NA NA NA NA 28501 FUN_016304 1275 630 757 932 1230 ptg000011l:1348046-1357082 O42406 1.08e-103 Homeobox protein SIX3 (CSIX3) (Sine oculis homeobox homolog 3) Gallus gallus (Chicken) apoptotic process involved in development [GO:1902742]; brain development [GO:0007420]; cell proliferation in forebrain [GO:0021846]; epithelial cell maturation [GO:0002070]; eye development [GO:0001654]; forebrain dorsal/ventral pattern formation [GO:0021798]; lens development in camera-type eye [GO:0002088]; lens fiber cell apoptotic process [GO:1990086]; lens fiber cell differentiation [GO:0070306]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of Wnt signaling pathway [GO:0030178]; neuroblast differentiation [GO:0014016]; neuroblast migration [GO:0097402]; optic vesicle morphogenesis [GO:0003404]; pituitary gland development [GO:0021983]; proximal/distal axis specification [GO:0009946]; regulation of cell cycle phase transition [GO:1901987]; regulation of cell population proliferation [GO:0042127]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of neural retina development [GO:0061074]; regulation of neuroblast proliferation [GO:1902692]; regulation of transcription by RNA polymerase II [GO:0006357]; telencephalon development [GO:0021537]; telencephalon regionalization [GO:0021978] GO:0000978; GO:0000981; GO:0001228; GO:0001654; GO:0002070; GO:0002088; GO:0003404; GO:0003677; GO:0005634; GO:0005667; GO:0006357; GO:0007420; GO:0009946; GO:0014016; GO:0021537; GO:0021798; GO:0021846; GO:0021978; GO:0021983; GO:0030178; GO:0042127; GO:0045665; GO:0045892; GO:0061074; GO:0070306; GO:0097402; GO:1901987; GO:1902692; GO:1902742; GO:1990086; GO:2000177 28502 FUN_016305 1495 767 655 1287 881 ptg000011l:1389199-1390985 Q6NZ04 1.56e-114 Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; apoptotic process [GO:0006915]; extraocular skeletal muscle development [GO:0002074]; inner ear development [GO:0048839]; peripheral nervous system neuron development [GO:0048935]; pharyngeal muscle development [GO:0043282]; regulation of skeletal muscle cell proliferation [GO:0014857]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle fiber development [GO:0048741]; striated muscle cell differentiation [GO:0051146] GO:0000978; GO:0000981; GO:0002074; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0006915; GO:0014857; GO:0021984; GO:0043282; GO:0048741; GO:0048839; GO:0048935; GO:0051146 28503 FUN_016306 59 29 77 146 90 ptg000011l:1419417-1423743 Q6NZ04 3.9e-71 Homeobox protein six1b (Homeobox protein six1a) (Sine oculis homeobox homolog 1a) (Sine oculis homeobox homolog 1b) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; apoptotic process [GO:0006915]; extraocular skeletal muscle development [GO:0002074]; inner ear development [GO:0048839]; peripheral nervous system neuron development [GO:0048935]; pharyngeal muscle development [GO:0043282]; regulation of skeletal muscle cell proliferation [GO:0014857]; regulation of transcription by RNA polymerase II [GO:0006357]; skeletal muscle fiber development [GO:0048741]; striated muscle cell differentiation [GO:0051146] GO:0000978; GO:0000981; GO:0002074; GO:0005634; GO:0005667; GO:0005737; GO:0006357; GO:0006915; GO:0014857; GO:0021984; GO:0043282; GO:0048741; GO:0048839; GO:0048935; GO:0051146 28504 FUN_016307 288 493 154 271 171 ptg000011l:1424960-1426930 D3ZTX0 1.38e-36 Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27) Rattus norvegicus (Rat) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0012507; GO:0030134; GO:0030663; GO:0033116 28505 FUN_003286 2 1 2 9 8 NA NA NA NA NA NA NA 28506 FUN_003285 13 2 20 0 18 NA NA NA NA NA NA NA 28507 FUN_003289 0 0 0 7 0 NA NA NA NA NA NA NA 28508 FUN_003288 8 0 11 8 2 NA NA NA NA NA NA NA 28509 FUN_016330 258 174 169 201 269 NA NA NA NA NA NA NA 28510 FUN_015649 3 7 20 227 27 NA NA NA NA NA NA NA 28511 FUN_016339 38106 44800 38603 49829 18171 ptg000011l:1839398-1841631 Q9CQ19 6.27e-52 Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) Mus musculus (Mouse) myofibril assembly [GO:0030239] GO:0001725; GO:0005509; GO:0005737; GO:0005938; GO:0016460; GO:0030016; GO:0030018; GO:0030239; GO:0032036 28512 FUN_023164 7 0 9 0 46 NA NA NA NA NA NA NA 28513 FUN_023165 1051 782 572 802 894 NA NA NA NA NA NA NA 28514 FUN_023166 3418 18 601 9451 1463 NA NA NA NA NA NA NA 28515 FUN_023160 1004 731 671 1085 741 NA NA NA NA NA NA NA 28516 FUN_023161 333 186 150 139 146 NA NA NA NA NA NA NA 28517 FUN_023162 161 159 141 242 73 ptg000017l:4344756-4351035 Q2KJ63 2.79e-24 Plasma kallikrein (EC 3.4.21.34) (Fletcher factor) (Kininogenin) (Plasma prekallikrein) [Cleaved into: Plasma kallikrein heavy chain; Plasma kallikrein light chain] Bos taurus (Bovine) blood coagulation [GO:0007596]; fibrinolysis [GO:0042730]; inflammatory response [GO:0006954]; plasminogen activation [GO:0031639]; positive regulation of fibrinolysis [GO:0051919] GO:0004252; GO:0005615; GO:0006954; GO:0007596; GO:0031639; GO:0042730; GO:0042803; GO:0051919 28518 FUN_023163 1189 432 290 523 519 NA NA NA NA NA NA NA 28519 FUN_023168 175 43 27 3 35 NA NA NA NA NA NA NA 28520 FUN_023169 546 619 371 526 372 NA NA NA NA NA NA NA 28521 FUN_022695 1333 605 529 878 793 NA NA NA NA NA NA NA 28522 FUN_028371 0 0 0 571 415 NA NA NA NA NA NA NA 28523 FUN_022697 4679 3089 2481 2684 1110 NA NA NA NA NA NA NA 28524 FUN_022696 4103 3844 2183 6637 5678 NA NA NA NA NA NA NA 28525 FUN_022691 2000 1327 1106 1288 1420 ptg000016l:12412244-12417470 Q4VBS4 3.66e-23 Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal [GO:0070084]; proteolysis [GO:0006508] GO:0005739; GO:0006508; GO:0046872; GO:0070006; GO:0070084 28526 FUN_022691 2000 1327 1106 1288 1420 ptg000016l:12412244-12417470 Q4VBS4 3.66e-23 Methionine aminopeptidase 1D, mitochondrial (MAP 1D) (MetAP 1D) (EC 3.4.11.18) (Methionyl aminopeptidase type 1D, mitochondrial) (Peptidase M 1D) Danio rerio (Zebrafish) (Brachydanio rerio) protein initiator methionine removal [GO:0070084]; proteolysis [GO:0006508] GO:0005739; GO:0006508; GO:0046872; GO:0070006; GO:0070084 28527 FUN_022690 1898 1905 1384 1752 1752 NA NA NA NA NA NA NA 28528 FUN_022693 1327 1352 738 561 1295 NA NA NA NA NA NA NA 28529 FUN_022692 0 808 404 48 161 NA NA NA NA NA NA NA 28530 FUN_022699 1555 1119 1017 1209 1429 NA NA NA NA NA NA NA 28531 FUN_022698 8589 10058 4480 8120 7684 NA NA NA NA NA NA NA 28532 FUN_028469 391 205 115 170 265 NA NA NA NA NA NA NA 28533 FUN_028460 0 0 0 15 0 NA NA NA NA NA NA NA 28534 FUN_028461 348 601 200 1377 1363 NA NA NA NA NA NA NA 28535 FUN_028462 64 369 133 807 326 NA NA NA NA NA NA NA 28536 FUN_028463 147 556 451 1278 231 NA NA NA NA NA NA NA 28537 FUN_028464 376 155 117 313 166 NA NA NA NA NA NA NA 28538 FUN_028465 614 273 125 296 204 NA NA NA NA NA NA NA 28539 FUN_028466 99 90 30 42 43 NA NA NA NA NA NA NA 28540 FUN_028467 357 310 166 340 478 NA NA NA NA NA NA NA 28541 FUN_036471 391 413 3 298 0 NA NA NA NA NA NA NA 28542 FUN_010179 0 0 6 0 0 NA NA NA NA NA NA NA 28543 FUN_011943 50 45 22 73 44 ptg000008l:3365724-3366762 C3ZQF9 2.39e-21 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 28544 FUN_011942 35 11 5 32 16 NA NA NA NA NA NA NA 28545 FUN_011941 1039 603 355 869 950 ptg000008l:3360909-3363695 A7SPW6 2.38e-64 Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) Nematostella vectensis (Starlet sea anemone) mitochondrial translational elongation [GO:0070125]; translational elongation [GO:0006414] GO:0003746; GO:0005759; GO:0006414; GO:0070125 28546 FUN_011940 989 681 405 808 467 NA NA NA NA NA NA NA 28547 FUN_011947 1806 1228 975 1344 1771 ptg000008l:3424532-3431741 Q8N5D0 1.4e-63 WD and tetratricopeptide repeats protein 1 Homo sapiens (Human) cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361] GO:0000122; GO:0001701; GO:0004857; GO:0005654; GO:0005737; GO:0005829; GO:0006006; GO:0008361; GO:0016567; GO:0032869; GO:0035264; GO:0042393; GO:0042826; GO:0045717; GO:0055082; GO:0080008 28548 FUN_011947 1806 1228 975 1344 1771 ptg000008l:3424532-3431741 Q8N5D0 1.63e-39 WD and tetratricopeptide repeats protein 1 Homo sapiens (Human) cellular chemical homeostasis [GO:0055082]; cellular response to insulin stimulus [GO:0032869]; glucose metabolic process [GO:0006006]; in utero embryonic development [GO:0001701]; multicellular organism growth [GO:0035264]; negative regulation of fatty acid biosynthetic process [GO:0045717]; negative regulation of transcription by RNA polymerase II [GO:0000122]; protein ubiquitination [GO:0016567]; regulation of cell size [GO:0008361] GO:0000122; GO:0001701; GO:0004857; GO:0005654; GO:0005737; GO:0005829; GO:0006006; GO:0008361; GO:0016567; GO:0032869; GO:0035264; GO:0042393; GO:0042826; GO:0045717; GO:0055082; GO:0080008 28549 FUN_011946 350 263 255 429 395 NA NA NA NA NA NA NA 28550 FUN_011945 1930 1275 864 1588 1052 NA NA NA NA NA NA NA 28551 FUN_011944 2221 1376 1025 2240 1574 NA NA NA NA NA NA NA 28552 FUN_011949 33 21 0 0 38 NA NA NA NA NA NA NA 28553 FUN_011948 1805 1414 769 1200 1013 NA NA NA NA NA NA NA 28554 FUN_025649 889 810 655 709 848 NA NA NA NA NA NA NA 28555 FUN_025648 57 128 125 224 78 NA NA NA NA NA NA NA 28556 FUN_017933 0 136 0 0 25 NA NA NA NA NA NA NA 28557 FUN_025643 9424 7058 5337 10062 9799 NA NA NA NA NA NA NA 28558 FUN_025642 4109 2831 1552 2345 1545 ptg000019l:5157846-5163561 Q9WU20 1.59e-75 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Mus musculus (Mouse) heterochromatin organization [GO:0070828]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; regulation of histone methylation [GO:0031060]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0001843; GO:0004489; GO:0005829; GO:0006555; GO:0009086; GO:0031060; GO:0035999; GO:0044877; GO:0045202; GO:0046653; GO:0050660; GO:0050661; GO:0050667; GO:0070828; GO:0071949; GO:0072341; GO:0106313 28559 FUN_025642 4109 2831 1552 2345 1545 ptg000019l:5157846-5163561 Q9WU20 4.09e-37 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Mus musculus (Mouse) heterochromatin organization [GO:0070828]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; regulation of histone methylation [GO:0031060]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0001843; GO:0004489; GO:0005829; GO:0006555; GO:0009086; GO:0031060; GO:0035999; GO:0044877; GO:0045202; GO:0046653; GO:0050660; GO:0050661; GO:0050667; GO:0070828; GO:0071949; GO:0072341; GO:0106313 28560 FUN_025642 4109 2831 1552 2345 1545 ptg000019l:5157846-5163561 Q9WU20 1.17e-30 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Mus musculus (Mouse) heterochromatin organization [GO:0070828]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; regulation of histone methylation [GO:0031060]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0001843; GO:0004489; GO:0005829; GO:0006555; GO:0009086; GO:0031060; GO:0035999; GO:0044877; GO:0045202; GO:0046653; GO:0050660; GO:0050661; GO:0050667; GO:0070828; GO:0071949; GO:0072341; GO:0106313 28561 FUN_025642 4109 2831 1552 2345 1545 ptg000019l:5157846-5163561 Q9WU20 1.17e-30 Methylenetetrahydrofolate reductase (NADPH) (EC 1.5.1.53) Mus musculus (Mouse) heterochromatin organization [GO:0070828]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; neural tube closure [GO:0001843]; regulation of histone methylation [GO:0031060]; tetrahydrofolate interconversion [GO:0035999]; tetrahydrofolate metabolic process [GO:0046653] GO:0001843; GO:0004489; GO:0005829; GO:0006555; GO:0009086; GO:0031060; GO:0035999; GO:0044877; GO:0045202; GO:0046653; GO:0050660; GO:0050661; GO:0050667; GO:0070828; GO:0071949; GO:0072341; GO:0106313 28562 FUN_025641 315 284 251 303 220 NA NA NA NA NA NA NA 28563 FUN_025640 465 266 317 254 603 ptg000019l:5127395-5130708 O00154 1.18e-46 Cytosolic acyl coenzyme A thioester hydrolase (EC 3.1.2.2) (Acyl-CoA thioesterase 7) (Brain acyl-CoA hydrolase) (BACH) (hBACH) (CTE-IIa) (CTE-II) (Long chain acyl-CoA thioester hydrolase) Homo sapiens (Human) acyl-CoA metabolic process [GO:0006637]; coenzyme A biosynthetic process [GO:0015937]; fatty acid metabolic process [GO:0006631]; long-chain fatty-acyl-CoA catabolic process [GO:0036116]; medium-chain fatty acid biosynthetic process [GO:0051792]; medium-chain fatty-acyl-CoA catabolic process [GO:0036114]; palmitic acid biosynthetic process [GO:1900535] GO:0000062; GO:0005654; GO:0005739; GO:0005829; GO:0006631; GO:0006637; GO:0015937; GO:0016290; GO:0036042; GO:0036114; GO:0036116; GO:0042803; GO:0047617; GO:0051792; GO:0070062; GO:0102991; GO:1900535 28564 FUN_025647 29 135 40 269 60 NA NA NA NA NA NA NA 28565 FUN_025646 52 42 6 101 56 NA NA NA NA NA NA NA 28566 FUN_025645 421 297 625 927 603 NA NA NA NA NA NA NA 28567 FUN_025644 8266 6343 4863 7978 5705 NA NA NA NA NA NA NA 28568 FUN_008149 173 359 219 291 143 NA NA NA NA NA NA NA 28569 FUN_008140 49 201 154 241 126 NA NA NA NA NA NA NA 28570 FUN_008143 46 43 3 0 32 NA NA NA NA NA NA NA 28571 FUN_024593 751 373 316 287 201 NA NA NA NA NA NA NA 28572 FUN_008145 0 0 0 0 20 NA NA NA NA NA NA NA 28573 FUN_024595 400 521 323 546 308 NA NA NA NA NA NA NA 28574 FUN_024596 1114 559 547 1063 906 ptg000018l:8799666-8813070 Q0IFL2 1.3e-23 RuvB-like helicase 1 (EC 3.6.4.12) (Pontin) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) cell cycle [GO:0007049]; cell division [GO:0051301]; chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; regulation of cell population proliferation [GO:0042127] GO:0003713; GO:0004386; GO:0005524; GO:0005634; GO:0006281; GO:0006310; GO:0006325; GO:0007049; GO:0008094; GO:0016887; GO:0042127; GO:0051301; GO:0090263 28575 FUN_008146 87 45 0 0 56 NA NA NA NA NA NA NA 28576 FUN_025995 99 21 33 130 52 NA NA NA NA NA NA NA 28577 FUN_044116 35 126 49 86 239 NA NA NA NA NA NA NA 28578 FUN_014277 1 32 9 28 0 NA NA NA NA NA NA NA 28579 FUN_014275 0 45 0 0 24 NA NA NA NA NA NA NA 28580 FUN_014272 0 60 0 0 0 NA NA NA NA NA NA NA 28581 FUN_014270 84 10 17 13 3 NA NA NA NA NA NA NA 28582 FUN_044111 66 144 123 154 375 NA NA NA NA NA NA NA 28583 FUN_024512 61 22 22 28 48 NA NA NA NA NA NA NA 28584 FUN_024513 45 40 25 0 144 NA NA NA NA NA NA NA 28585 FUN_022349 32 160 143 12 86 NA NA NA NA NA NA NA 28586 FUN_022348 2 18 59 0 12 NA NA NA NA NA NA NA 28587 FUN_022347 23 208 189 28 54 NA NA NA NA NA NA NA 28588 FUN_022346 29723 27897 11790 29239 19855 ptg000016l:7881979-7886339 Q9XSU3 9.48e-28 60S ribosomal protein L23 Canis lupus familiaris (Dog) (Canis familiaris) translation [GO:0006412] GO:0003735; GO:0006412; GO:0022625; GO:0070180 28589 FUN_022345 1711 1221 539 1029 608 NA NA NA NA NA NA NA 28590 FUN_022344 1076 827 451 898 636 NA NA NA NA NA NA NA 28591 FUN_022343 172 275 319 347 374 NA NA NA NA NA NA NA 28592 FUN_022342 1566 1040 293 875 1504 NA NA NA NA NA NA NA 28593 FUN_022341 97 104 69 47 159 NA NA NA NA NA NA NA 28594 FUN_022340 5494 3654 2532 5341 4311 NA NA NA NA NA NA NA 28595 FUN_024518 2 7 4 0 5 NA NA NA NA NA NA NA 28596 FUN_024519 650 509 598 516 847 ptg000018l:7646451-7801568 P46023 1.05e-71 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 28597 FUN_006284 88 0 34 622 960 ptg000001l:10118040-10148472 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 28598 FUN_006284 88 0 34 622 960 ptg000001l:10118040-10148472 O15050 2.37e-28 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 28599 FUN_006265 429 253 76 240 148 NA NA NA NA NA NA NA 28600 FUN_006285 5 0 0 203 279 NA NA NA NA NA NA NA 28601 FUN_014898 40 60 77 33 89 NA NA NA NA NA NA NA 28602 FUN_014899 1026 646 523 887 752 NA NA NA NA NA NA NA 28603 FUN_014892 632 624 478 779 428 NA NA NA NA NA NA NA 28604 FUN_014893 2837 2464 1547 2368 1947 NA NA NA NA NA NA NA 28605 FUN_014890 1107 512 502 810 831 NA NA NA NA NA NA NA 28606 FUN_014891 517 297 286 670 943 NA NA NA NA NA NA NA 28607 FUN_014896 6164 2500 2622 5039 4937 NA NA NA NA NA NA NA 28608 FUN_014897 2134 1191 1246 2758 2240 ptg000009l:4056657-4091432 Q9Y4D8 4.15e-28 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 28609 FUN_014897 2134 1191 1246 2758 2240 ptg000009l:4056657-4091432 Q9Y4D8 4.15e-28 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 28610 FUN_014897 2134 1191 1246 2758 2240 ptg000009l:4056657-4091432 Q9Y4D8 3.08e-21 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 28611 FUN_014897 2134 1191 1246 2758 2240 ptg000009l:4056657-4091432 Q9Y4D8 7.12e-21 Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) Homo sapiens (Human) glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006] GO:0004842; GO:0006006; GO:0016020; GO:0042593 28612 FUN_014894 11 0 0 0 3 NA NA NA NA NA NA NA 28613 FUN_014895 15702 10820 6808 9980 4695 NA NA NA NA NA NA NA 28614 FUN_026307 189 115 343 367 188 NA NA NA NA NA NA NA 28615 FUN_026306 4188 2167 2684 2131 989 NA NA NA NA NA NA NA 28616 FUN_006288 34 0 201 26 374 NA NA NA NA NA NA NA 28617 FUN_023153 1442 967 885 1925 1529 NA NA NA NA NA NA NA 28618 FUN_006289 0 0 44 9 0 NA NA NA NA NA NA NA 28619 FUN_023152 13 0 0 24 0 NA NA NA NA NA NA NA 28620 FUN_023155 312 384 222 483 598 NA NA NA NA NA NA NA 28621 FUN_026302 316 142 84 332 340 NA NA NA NA NA NA NA 28622 FUN_023157 522 225 200 667 747 NA NA NA NA NA NA NA 28623 FUN_023156 429 479 460 637 864 NA NA NA NA NA NA NA 28624 FUN_038502 10476 6765 4610 8111 3932 ptg000027l:8071248-8088673 P83871 3.58e-27 PHD finger-like domain-containing protein 5A (PHD finger-like domain protein 5A) (Splicing factor 3B-associated 14 kDa protein) (SF3b14b) Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398]; positive regulation of DNA-templated transcription [GO:0045893]; stem cell differentiation [GO:0048863] GO:0000398; GO:0003677; GO:0003723; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0008270; GO:0016363; GO:0016607; GO:0045893; GO:0048863; GO:0071005; GO:0071011 28625 FUN_038503 50982 88266 46019 78775 37888 NA NA NA NA NA NA NA 28626 FUN_038500 10161 6430 8410 6025 4064 NA NA NA NA NA NA NA 28627 FUN_038501 7 10 5 7 66 NA NA NA NA NA NA NA 28628 FUN_038506 18 1118 1633 11 689 NA NA NA NA NA NA NA 28629 FUN_038507 726 940 469 483 423 NA NA NA NA NA NA NA 28630 FUN_038504 917 1209 660 701 797 NA NA NA NA NA NA NA 28631 FUN_038505 2089 889 841 1279 849 NA NA NA NA NA NA NA 28632 FUN_038508 6115 7061 3759 6789 4343 ptg000027l:8154011-8166574 P00514 6.7e-30 cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed] Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cardiac muscle cell proliferation [GO:0060038]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of gene expression [GO:0010629]; positive regulation of insulin secretion [GO:0032024]; sarcomere organization [GO:0045214] GO:0001707; GO:0001772; GO:0004862; GO:0005737; GO:0005771; GO:0005813; GO:0005930; GO:0005952; GO:0007189; GO:0010629; GO:0019904; GO:0030552; GO:0031588; GO:0031594; GO:0031625; GO:0032024; GO:0034236; GO:0042802; GO:0044853; GO:0045214; GO:0046007; GO:0060038; GO:0097224; GO:0098978; GO:2000480 28633 FUN_038508 6115 7061 3759 6789 4343 ptg000027l:8154011-8166574 P00514 9.67e-30 cAMP-dependent protein kinase type I-alpha regulatory subunit [Cleaved into: cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed] Bos taurus (Bovine) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cardiac muscle cell proliferation [GO:0060038]; mesoderm formation [GO:0001707]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of cAMP-dependent protein kinase activity [GO:2000480]; negative regulation of gene expression [GO:0010629]; positive regulation of insulin secretion [GO:0032024]; sarcomere organization [GO:0045214] GO:0001707; GO:0001772; GO:0004862; GO:0005737; GO:0005771; GO:0005813; GO:0005930; GO:0005952; GO:0007189; GO:0010629; GO:0019904; GO:0030552; GO:0031588; GO:0031594; GO:0031625; GO:0032024; GO:0034236; GO:0042802; GO:0044853; GO:0045214; GO:0046007; GO:0060038; GO:0097224; GO:0098978; GO:2000480 28634 FUN_038509 277 339 231 299 617 NA NA NA NA NA NA NA 28635 FUN_023906 430 12 28 16 19 NA NA NA NA NA NA NA 28636 FUN_031621 0 130 0 0 0 NA NA NA NA NA NA NA 28637 FUN_031623 0 32 9 0 0 NA NA NA NA NA NA NA 28638 FUN_023903 4 16 2 211 0 NA NA NA NA NA NA NA 28639 FUN_031626 30 66 40 94 7 NA NA NA NA NA NA NA 28640 FUN_031629 468 823 1243 2731 1321 NA NA NA NA NA NA NA 28641 FUN_023909 0 0 0 0 10 NA NA NA NA NA NA NA 28642 FUN_039456 7 0 0 0 0 NA NA NA NA NA NA NA 28643 FUN_039451 0 0 0 0 13 NA NA NA NA NA NA NA 28644 FUN_039458 9 0 8 0 36 NA NA NA NA NA NA NA 28645 FUN_022686 208 152 45 92 131 NA NA NA NA NA NA NA 28646 FUN_025655 240 289 137 158 117 NA NA NA NA NA NA NA 28647 FUN_022684 245 95 195 286 251 NA NA NA NA NA NA NA 28648 FUN_025657 1984 969 1377 1181 1084 ptg000019l:5343993-5346424 P49140 6.32e-48 Ski oncogene (Proto-oncogene c-Ski) Gallus gallus (Chicken) negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512] GO:0005634; GO:0005667; GO:0019904; GO:0030512; GO:0042803; GO:0043565; GO:0046332; GO:0140297 28649 FUN_022682 11299 12158 6441 8266 3904 ptg000016l:12371286-12374716 Q8R5H8 1.01e-40 Fas apoptotic inhibitory molecule 1 (rFAIM) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; positive regulation of neurogenesis [GO:0050769] GO:0005737; GO:0006915; GO:0007249; GO:0050769; GO:1902042 28650 FUN_022683 647 613 393 604 632 NA NA NA NA NA NA NA 28651 FUN_018481 9 24 0 0 0 NA NA NA NA NA NA NA 28652 FUN_034052 18 0 0 11 0 NA NA NA NA NA NA NA 28653 FUN_026857 6 0 48 6 65 NA NA NA NA NA NA NA 28654 FUN_026856 0 0 0 0 29 NA NA NA NA NA NA NA 28655 FUN_026852 7 0 0 0 0 NA NA NA NA NA NA NA 28656 FUN_026851 0 0 192 0 0 NA NA NA NA NA NA NA 28657 FUN_026850 4 48 11 0 14 NA NA NA NA NA NA NA 28658 FUN_034054 240 476 342 320 281 ptg000024l:4203276-4208902 Q09081 3.43e-85 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 28659 FUN_026859 4 13 35 17 44 NA NA NA NA NA NA NA 28660 FUN_034055 2339 1335 928 1887 1537 ptg000024l:4214311-4243131 O08873 6.76e-65 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 28661 FUN_034055 2339 1335 928 1887 1537 ptg000024l:4214311-4243131 O08873 4.17e-33 MAP kinase-activating death domain protein (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (RabGEP) Rattus norvegicus (Rat) anterograde synaptic vesicle transport [GO:0048490]; execution phase of apoptosis [GO:0097194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of growth hormone secretion [GO:0060125]; negative regulation of pancreatic amylase secretion [GO:1902277]; positive regulation of MAPK cascade [GO:0043410]; regulation of apoptotic process [GO:0042981]; regulation of cell cycle [GO:0051726]; regulation of extrinsic apoptotic signaling pathway [GO:2001236]; regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902041]; regulation of Rab protein signal transduction [GO:0032483] GO:0005085; GO:0005634; GO:0005829; GO:0005886; GO:0008021; GO:0016020; GO:0030424; GO:0032483; GO:0042981; GO:0043410; GO:0045202; GO:0048490; GO:0051726; GO:0060125; GO:0097194; GO:1902041; GO:1902277; GO:1904115; GO:2001234; GO:2001236 28662 FUN_018486 0 0 0 0 10 NA NA NA NA NA NA NA 28663 FUN_037507 40 155 248 140 85 NA NA NA NA NA NA NA 28664 FUN_037506 157 5798 3481 150 1214 NA NA NA NA NA NA NA 28665 FUN_037505 76 54 31 50 100 NA NA NA NA NA NA NA 28666 FUN_037504 21 18 3 17 27 NA NA NA NA NA NA NA 28667 FUN_037503 32 31 16 29 27 NA NA NA NA NA NA NA 28668 FUN_037502 571 802 524 603 556 NA NA NA NA NA NA NA 28669 FUN_037501 280 281 316 390 258 NA NA NA NA NA NA NA 28670 FUN_037500 131 6745 1900 143 993 NA NA NA NA NA NA NA 28671 FUN_037509 195 168 65 88 50 NA NA NA NA NA NA NA 28672 FUN_037508 12 16 64 0 149 NA NA NA NA NA NA NA 28673 FUN_008085 210 114 92 132 220 NA NA NA NA NA NA NA 28674 FUN_033904 545 602 665 1290 1026 NA NA NA NA NA NA NA 28675 FUN_027102 6 0 10 0 176 NA NA NA NA NA NA NA 28676 FUN_027103 0 0 10 0 171 NA NA NA NA NA NA NA 28677 FUN_027100 0 3 0 0 13 NA NA NA NA NA NA NA 28678 FUN_027101 6 3 5 20 16 NA NA NA NA NA NA NA 28679 FUN_027106 1 0 2 0 22 NA NA NA NA NA NA NA 28680 FUN_027107 1 0 0 0 8 NA NA NA NA NA NA NA 28681 FUN_027104 2 0 13 0 109 NA NA NA NA NA NA NA 28682 FUN_027105 6 0 8 0 141 NA NA NA NA NA NA NA 28683 FUN_027108 0 0 0 0 20 NA NA NA NA NA NA NA 28684 FUN_027109 0 0 0 0 18 NA NA NA NA NA NA NA 28685 FUN_030999 12 0 0 0 0 NA NA NA NA NA NA NA 28686 FUN_030998 17 4 26 11 217 NA NA NA NA NA NA NA 28687 FUN_030995 158 0 161 193 173 NA NA NA NA NA NA NA 28688 FUN_030996 4 3 3 7 7 NA NA NA NA NA NA NA 28689 FUN_030990 0 0 17 0 0 NA NA NA NA NA NA NA 28690 FUN_030992 0 0 11 37 48 NA NA NA NA NA NA NA 28691 FUN_014831 63 0 13 6 99 NA NA NA NA NA NA NA 28692 FUN_019302 0 0 0 0 18 NA NA NA NA NA NA NA 28693 FUN_023483 57 30 5 39 7 NA NA NA NA NA NA NA 28694 FUN_023482 13 2 48 4 148 NA NA NA NA NA NA NA 28695 FUN_023480 3 3 9 0 30 NA NA NA NA NA NA NA 28696 FUN_041075 29 4 88 7 154 NA NA NA NA NA NA NA 28697 FUN_033970 431 239 205 380 337 ptg000024l:3256387-3262405 Q4V7B1 7.11e-51 Protein CFAP20DC Rattus norvegicus (Rat) NA NA 28698 FUN_033971 548 303 274 478 569 NA NA NA NA NA NA NA 28699 FUN_033976 1246 553 338 629 733 NA NA NA NA NA NA NA 28700 FUN_033977 80 42 126 91 439 NA NA NA NA NA NA NA 28701 FUN_033974 36 5 10 0 19 NA NA NA NA NA NA NA 28702 FUN_004249 0 97 17 9 4 NA NA NA NA NA NA NA 28703 FUN_004246 900 368 435 1192 274 NA NA NA NA NA NA NA 28704 FUN_004247 5952 2823 2401 5466 4036 ntLink_8:21045362-21079281 O95477 2.73e-38 Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to retinoic acid [GO:0071300]; cholesterol efflux [GO:0033344]; cholesterol homeostasis [GO:0042632]; cholesterol metabolic process [GO:0008203]; endosomal transport [GO:0016197]; export across plasma membrane [GO:0140115]; G protein-coupled receptor signaling pathway [GO:0007186]; high-density lipoprotein particle assembly [GO:0034380]; intracellular cholesterol transport [GO:0032367]; lipid transport [GO:0006869]; lysosome organization [GO:0007040]; negative regulation of cholesterol storage [GO:0010887]; negative regulation of macrophage derived foam cell differentiation [GO:0010745]; peptide secretion [GO:0002790]; phagocytosis, engulfment [GO:0006911]; phospholipid efflux [GO:0033700]; phospholipid homeostasis [GO:0055091]; phospholipid translocation [GO:0045332]; platelet dense granule organization [GO:0060155]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of high-density lipoprotein particle assembly [GO:0090108]; protein lipidation [GO:0006497]; protein secretion [GO:0009306]; protein transmembrane transport [GO:0071806]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of high-density lipoprotein particle assembly [GO:0090107]; response to laminar fluid shear stress [GO:0034616]; reverse cholesterol transport [GO:0043691]; signal release [GO:0023061] GO:0002790; GO:0005102; GO:0005319; GO:0005524; GO:0005548; GO:0005768; GO:0005789; GO:0005794; GO:0005886; GO:0006497; GO:0006869; GO:0006911; GO:0007040; GO:0007186; GO:0007189; GO:0008203; GO:0008320; GO:0009306; GO:0009897; GO:0010745; GO:0010875; GO:0010887; GO:0015485; GO:0016197; GO:0016887; GO:0019905; GO:0023061; GO:0030139; GO:0031210; GO:0031267; GO:0032367; GO:0032489; GO:0033344; GO:0033700; GO:0034185; GO:0034186; GO:0034188; GO:0034380; GO:0034616; GO:0042626; GO:0042632; GO:0043231; GO:0043691; GO:0045121; GO:0045332; GO:0045335; GO:0046623; GO:0048471; GO:0051117; GO:0055091; GO:0060155; GO:0071222; GO:0071300; GO:0071404; GO:0071806; GO:0090107; GO:0090108; GO:0090554; GO:0090556; GO:0097708; GO:0120020; GO:0140115; GO:0140328; GO:0140359 28705 FUN_033978 181 149 41 444 94 ptg000024l:3308298-3318339 Q8N961 2.74e-25 Ankyrin repeat and BTB/POZ domain-containing protein 2 Homo sapiens (Human) cellular response to toxic substance [GO:0097237] GO:0046982; GO:0097237 28706 FUN_004245 930 2234 1908 1210 1895 NA NA NA NA NA NA NA 28707 FUN_004242 1927 2023 1653 1377 2438 NA NA NA NA NA NA NA 28708 FUN_004243 524 725 411 551 789 NA NA NA NA NA NA NA 28709 FUN_004240 611 319 608 693 785 NA NA NA NA NA NA NA 28710 FUN_004241 129 277 180 79 127 NA NA NA NA NA NA NA 28711 FUN_042379 0 0 0 55 0 NA NA NA NA NA NA NA 28712 FUN_001889 4800 2652 2668 4104 3342 NA NA NA NA NA NA NA 28713 FUN_016604 768 570 415 657 576 NA NA NA NA NA NA NA 28714 FUN_019125 6 0 0 11 23 NA NA NA NA NA NA NA 28715 FUN_019124 11 48 0 0 35 NA NA NA NA NA NA NA 28716 FUN_019127 557 187 224 477 452 NA NA NA NA NA NA NA 28717 FUN_019126 48 2 31 217 88 NA NA NA NA NA NA NA 28718 FUN_019123 0 9 0 0 21 NA NA NA NA NA NA NA 28719 FUN_019122 0 0 0 0 19 NA NA NA NA NA NA NA 28720 FUN_019129 263 229 89 78 95 NA NA NA NA NA NA NA 28721 FUN_019128 168 243 147 247 106 NA NA NA NA NA NA NA 28722 FUN_030238 3 0 3 1 17 ptg000023l:10434215-10434978 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28723 FUN_033825 270 133 121 292 169 ptg000024l:1700800-1704514 Q6L8S8 3.29e-27 Beta-1,4-N-acetylgalactosaminyltransferase 3 (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206] GO:0005794; GO:0008376; GO:0030206; GO:0032580; GO:0033842; GO:0043231; GO:0047238 28724 FUN_019821 6 0 7 0 8 NA NA NA NA NA NA NA 28725 FUN_030231 2 0 3 0 11 ptg000023l:10418007-10418770 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28726 FUN_030233 3 0 3 0 12 ptg000023l:10422059-10422822 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28727 FUN_030236 4 0 2 0 17 ptg000023l:10430163-10430926 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28728 FUN_021193 15 0 15 3 56 NA NA NA NA NA NA NA 28729 FUN_021192 7 0 26 32 0 NA NA NA NA NA NA NA 28730 FUN_014811 778 1721 770 1792 1998 NA NA NA NA NA NA NA 28731 FUN_021197 337 444 340 562 482 NA NA NA NA NA NA NA 28732 FUN_021196 235 190 273 369 244 NA NA NA NA NA NA NA 28733 FUN_021194 269 341 241 322 356 NA NA NA NA NA NA NA 28734 FUN_019824 77 104 35 7 53 NA NA NA NA NA NA NA 28735 FUN_021198 31 0 0 6 39 NA NA NA NA NA NA NA 28736 FUN_019825 231 390 108 62 154 NA NA NA NA NA NA NA 28737 FUN_019826 201 224 17 0 232 NA NA NA NA NA NA NA 28738 FUN_019827 21 0 0 0 84 NA NA NA NA NA NA NA 28739 FUN_013845 31 14 9 48 22 NA NA NA NA NA NA NA 28740 FUN_014531 1388 1253 1315 945 816 NA NA NA NA NA NA NA 28741 FUN_014530 37855 45718 20674 34554 26733 ptg000009l:974250-977764 P52301 3.31e-51 GTP-binding nuclear protein Ran (EC 3.6.5.-) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) Xenopus laevis (African clawed frog) eye development [GO:0001654]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015] GO:0000055; GO:0000056; GO:0000070; GO:0000287; GO:0001654; GO:0003924; GO:0005525; GO:0005634; GO:0005635; GO:0005829; GO:0006606; GO:0046039; GO:0061015 28742 FUN_014530 37855 45718 20674 34554 26733 ptg000009l:974250-977764 P52301 9.02e-25 GTP-binding nuclear protein Ran (EC 3.6.5.-) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) Xenopus laevis (African clawed frog) eye development [GO:0001654]; GTP metabolic process [GO:0046039]; mitotic sister chromatid segregation [GO:0000070]; protein import into nucleus [GO:0006606]; ribosomal large subunit export from nucleus [GO:0000055]; ribosomal small subunit export from nucleus [GO:0000056]; snRNA import into nucleus [GO:0061015] GO:0000055; GO:0000056; GO:0000070; GO:0000287; GO:0001654; GO:0003924; GO:0005525; GO:0005634; GO:0005635; GO:0005829; GO:0006606; GO:0046039; GO:0061015 28743 FUN_013741 12 45 21 24 58 NA NA NA NA NA NA NA 28744 FUN_014535 533 427 699 861 1016 NA NA NA NA NA NA NA 28745 FUN_021449 1701 943 926 1663 1448 ptg000016l:1997518-2022759 Q13416 3.01e-22 Origin recognition complex subunit 2 Homo sapiens (Human) DNA replication initiation [GO:0006270]; negative regulation of transcription by RNA polymerase II [GO:0000122] GO:0000122; GO:0000781; GO:0000792; GO:0000808; GO:0000939; GO:0003688; GO:0005634; GO:0005654; GO:0005664; GO:0005813; GO:0006270; GO:0016020 28746 FUN_014537 1268 716 907 634 362 ptg000009l:1032852-1041614 A6QQL0 9.75e-25 Solute carrier family 15 member 4 (Peptide/histidine transporter 1) Bos taurus (Bovine) dipeptide import across plasma membrane [GO:0140206]; histidine transport [GO:0015817]; innate immune response [GO:0045087]; L-histidine transmembrane export from vacuole [GO:0089708]; mast cell homeostasis [GO:0033023]; peptidoglycan transport [GO:0015835]; positive regulation of innate immune response [GO:0045089]; positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070430]; positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070434]; positive regulation of toll-like receptor 7 signaling pathway [GO:0034157]; positive regulation of toll-like receptor 8 signaling pathway [GO:0034161]; positive regulation of toll-like receptor 9 signaling pathway [GO:0034165]; protein transport [GO:0015031]; regulation of isotype switching to IgG isotypes [GO:0048302]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; transmembrane transport [GO:0055085] GO:0005290; GO:0005765; GO:0015031; GO:0015333; GO:0015647; GO:0015817; GO:0015835; GO:0016020; GO:0022857; GO:0031901; GO:0033023; GO:0034157; GO:0034161; GO:0034165; GO:0036020; GO:0045087; GO:0045089; GO:0048302; GO:0055085; GO:0070424; GO:0070430; GO:0070434; GO:0071916; GO:0089708; GO:0140206 28747 FUN_014536 643 344 192 358 174 NA NA NA NA NA NA NA 28748 FUN_035468 5530 9846 5292 10681 8122 ptg000025l:7702781-7707570 Q8BH04 2.71e-55 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Mus musculus (Mouse) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to lipid [GO:0033993]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006090; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071549 28749 FUN_035468 5530 9846 5292 10681 8122 ptg000025l:7702781-7707570 Q8BH04 3.87e-52 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Mus musculus (Mouse) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to lipid [GO:0033993]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006090; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071549 28750 FUN_035468 5530 9846 5292 10681 8122 ptg000025l:7702781-7707570 Q8BH04 1.61e-45 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Mus musculus (Mouse) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to lipid [GO:0033993]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006090; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071549 28751 FUN_035468 5530 9846 5292 10681 8122 ptg000025l:7702781-7707570 Q8BH04 1.26e-23 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Mus musculus (Mouse) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; pyruvate metabolic process [GO:0006090]; response to lipid [GO:0033993]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006090; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071549 28752 FUN_035469 4581 2743 2429 3041 2472 NA NA NA NA NA NA NA 28753 FUN_035462 1835 1037 339 768 390 ptg000025l:7644354-7645059 Q9SY73 5.4e-64 NADPH-dependent pterin aldehyde reductase (EC 1.1.1.-) Arabidopsis thaliana (Mouse-ear cress) folic acid-containing compound metabolic process [GO:0006760] GO:0005829; GO:0006760; GO:0016616 28754 FUN_035463 0 0 25 0 14 NA NA NA NA NA NA NA 28755 FUN_035460 1559 1956 768 1444 747 ptg000025l:7623858-7625037 Q9SY73 9.2e-62 NADPH-dependent pterin aldehyde reductase (EC 1.1.1.-) Arabidopsis thaliana (Mouse-ear cress) folic acid-containing compound metabolic process [GO:0006760] GO:0005829; GO:0006760; GO:0016616 28756 FUN_035461 11 0 22 12 0 NA NA NA NA NA NA NA 28757 FUN_035466 794 528 819 689 1171 NA NA NA NA NA NA NA 28758 FUN_035467 734 444 540 737 389 ptg000025l:7690136-7695911 Q16822 5.41e-70 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032496; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071356; GO:0071549 28759 FUN_035467 734 444 540 737 389 ptg000025l:7690136-7695911 Q16822 4.93e-58 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032496; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071356; GO:0071549 28760 FUN_035467 734 444 540 737 389 ptg000025l:7690136-7695911 Q16822 6.31e-45 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; cellular response to glucose stimulus [GO:0071333]; cellular response to insulin stimulus [GO:0032869]; cellular response to tumor necrosis factor [GO:0071356]; gluconeogenesis [GO:0006094]; glycerol biosynthetic process from pyruvate [GO:0046327]; hepatocyte differentiation [GO:0070365]; NADH oxidation [GO:0006116]; oxaloacetate metabolic process [GO:0006107]; positive regulation of insulin secretion [GO:0032024]; propionate catabolic process [GO:0019543]; response to lipid [GO:0033993]; response to lipopolysaccharide [GO:0032496]; response to starvation [GO:0042594] GO:0004611; GO:0004613; GO:0005525; GO:0005739; GO:0005759; GO:0005829; GO:0006094; GO:0006107; GO:0006116; GO:0019543; GO:0030145; GO:0032024; GO:0032496; GO:0032869; GO:0033993; GO:0042594; GO:0046327; GO:0070365; GO:0071333; GO:0071356; GO:0071549 28761 FUN_035465 1392 948 707 1418 1556 NA NA NA NA NA NA NA 28762 FUN_042772 0 0 3 0 8 ptg000043l:66588-67351 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28763 FUN_042775 0 0 6 3 7 ptg000043l:71683-73998 P35061 6.65e-78 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28764 FUN_042776 9 9 23 5 156 NA NA NA NA NA NA NA 28765 FUN_042777 51 114 85 69 214 NA NA NA NA NA NA NA 28766 FUN_042778 27 53 67 69 193 NA NA NA NA NA NA NA 28767 FUN_042779 0 0 0 2 10 NA NA NA NA NA NA NA 28768 FUN_031549 2452 2119 1382 1320 1013 NA NA NA NA NA NA NA 28769 FUN_031548 80 46 62 69 112 NA NA NA NA NA NA NA 28770 FUN_031541 229 364 198 301 201 ptg000023l:22728737-22731599 F7ASZ0 8.64e-22 BTB/POZ domain-containing protein 3 Callithrix jacchus (White-tufted-ear marmoset) cerebral cortex development [GO:0021987]; dendrite morphogenesis [GO:0048813] GO:0005634; GO:0005829; GO:0021987; GO:0048813 28771 FUN_031540 107 113 137 826 134 NA NA NA NA NA NA NA 28772 FUN_031543 248 86 61 613 133 NA NA NA NA NA NA NA 28773 FUN_031542 214 58 146 1410 264 NA NA NA NA NA NA NA 28774 FUN_031545 36 0 0 69 9 NA NA NA NA NA NA NA 28775 FUN_031544 12 13 9 100 25 NA NA NA NA NA NA NA 28776 FUN_031547 15 0 0 0 0 NA NA NA NA NA NA NA 28777 FUN_031546 13 23 27 47 61 ptg000023l:22752735-22753830 Q0KK59 1.75e-30 Protein unc-79 homolog Mus musculus (Mouse) adult behavior [GO:0030534]; behavioral response to ethanol [GO:0048149]; multicellular organism growth [GO:0035264] GO:0005886; GO:0030534; GO:0035264; GO:0048149 28778 FUN_004518 17 6 27 15 26 NA NA NA NA NA NA NA 28779 FUN_001592 805 438 526 548 705 NA NA NA NA NA NA NA 28780 FUN_004512 4143 3121 1707 2323 1584 ntLink_8:23892124-23932971 Q8CID0 2e-44 Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14) Mus musculus (Mouse) G2/M transition of mitotic cell cycle [GO:0000086]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000086; GO:0004402; GO:0005634; GO:0005737; GO:0006355; GO:0006357; GO:0016573; GO:0031063; GO:0043966; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140672 28781 FUN_004512 4143 3121 1707 2323 1584 ntLink_8:23892124-23932971 Q8CID0 5.12e-44 Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (ADA2A-containing complex subunit 2) (ATAC2) (CRP2-binding partner) (CRP2BP) (Lysine acetyltransferase 14) Mus musculus (Mouse) G2/M transition of mitotic cell cycle [GO:0000086]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000086; GO:0004402; GO:0005634; GO:0005737; GO:0006355; GO:0006357; GO:0016573; GO:0031063; GO:0043966; GO:0044154; GO:0045995; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140672 28782 FUN_001598 1027 1091 759 1719 1436 NA NA NA NA NA NA NA 28783 FUN_032168 69 451 42 23 11 NA NA NA NA NA NA NA 28784 FUN_032169 8 6 47 55 177 NA NA NA NA NA NA NA 28785 FUN_032166 623 344 352 751 459 ptg000023l:29355115-29376742 O60336 6.84e-23 Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1) Homo sapiens (Human) negative regulation of defense response to bacterium [GO:1900425]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; positive regulation of JNK cascade [GO:0046330] GO:0005654; GO:0005730; GO:0005737; GO:0032717; GO:0043124; GO:0046330; GO:0097431; GO:1900425 28786 FUN_032166 623 344 352 751 459 ptg000023l:29355115-29376742 O60336 6.84e-23 Mitogen-activated protein kinase-binding protein 1 (JNK-binding protein 1) (JNKBP-1) Homo sapiens (Human) negative regulation of defense response to bacterium [GO:1900425]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interleukin-8 production [GO:0032717]; positive regulation of JNK cascade [GO:0046330] GO:0005654; GO:0005730; GO:0005737; GO:0032717; GO:0043124; GO:0046330; GO:0097431; GO:1900425 28787 FUN_032167 5048 4399 2699 4619 2810 ptg000023l:29378320-29397221 Q60452 1.43e-51 General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) apoptotic process [GO:0006915]; chromosome segregation [GO:0007059]; hair cell differentiation [GO:0035315]; nucleotide-excision repair [GO:0006289]; regulation of mitotic cell cycle phase transition [GO:1901990]; response to oxidative stress [GO:0006979]; transcription by RNA polymerase II [GO:0006366]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0003677; GO:0005524; GO:0005634; GO:0005675; GO:0005737; GO:0005819; GO:0006283; GO:0006289; GO:0006366; GO:0006915; GO:0006979; GO:0007059; GO:0008022; GO:0016887; GO:0035315; GO:0043139; GO:0046872; GO:0047485; GO:0051539; GO:0070516; GO:0071817; GO:1901990 28788 FUN_032164 3715 4228 2875 3109 1879 ptg000023l:29330470-29330806 O73930 4.12e-46 Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (cDcoH) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD) Gallus gallus (Chicken) tetrahydrobiopterin biosynthetic process [GO:0006729] GO:0005634; GO:0005737; GO:0006729; GO:0008124 28789 FUN_032165 1846 2326 1020 1512 1235 NA NA NA NA NA NA NA 28790 FUN_032162 11719 8842 6511 9716 5574 ptg000023l:29313501-29320084 Q5I085 4.71e-45 Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; regulation of cell adhesion [GO:0030155] GO:0005634; GO:0005977; GO:0007049; GO:0017018; GO:0030155; GO:0046872; GO:0050115; GO:0051301; GO:0072357 28791 FUN_032162 11719 8842 6511 9716 5574 ptg000023l:29313501-29320084 Q5I085 3.5e-24 Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; regulation of cell adhesion [GO:0030155] GO:0005634; GO:0005977; GO:0007049; GO:0017018; GO:0030155; GO:0046872; GO:0050115; GO:0051301; GO:0072357 28792 FUN_032162 11719 8842 6511 9716 5574 ptg000023l:29313501-29320084 Q5I085 5.49e-21 Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cell cycle [GO:0007049]; cell division [GO:0051301]; glycogen metabolic process [GO:0005977]; regulation of cell adhesion [GO:0030155] GO:0005634; GO:0005977; GO:0007049; GO:0017018; GO:0030155; GO:0046872; GO:0050115; GO:0051301; GO:0072357 28793 FUN_032163 2357 1733 748 2017 1437 ptg000023l:29322316-29329755 P33992 4.58e-43 DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46) Homo sapiens (Human) cell cycle [GO:0007049]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003688; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0006260; GO:0006268; GO:0006270; GO:0007049; GO:0016020; GO:0016887; GO:0030174; GO:0042555; GO:0071162 28794 FUN_032163 2357 1733 748 2017 1437 ptg000023l:29322316-29329755 P33992 5.26e-22 DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46) Homo sapiens (Human) cell cycle [GO:0007049]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003688; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0006260; GO:0006268; GO:0006270; GO:0007049; GO:0016020; GO:0016887; GO:0030174; GO:0042555; GO:0071162 28795 FUN_032163 2357 1733 748 2017 1437 ptg000023l:29322316-29329755 P33992 8.51e-21 DNA replication licensing factor MCM5 (EC 3.6.4.12) (CDC46 homolog) (P1-CDC46) Homo sapiens (Human) cell cycle [GO:0007049]; DNA replication [GO:0006260]; DNA replication initiation [GO:0006270]; DNA unwinding involved in DNA replication [GO:0006268]; double-strand break repair via break-induced replication [GO:0000727]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000727; GO:0000781; GO:0003688; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0006260; GO:0006268; GO:0006270; GO:0007049; GO:0016020; GO:0016887; GO:0030174; GO:0042555; GO:0071162 28796 FUN_032160 4792 3479 2131 4725 2993 ptg000023l:29296180-29308966 Q3UJK4 2.76e-47 GTP-binding protein 2 (GTP-binding-like protein 2) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0006414; GO:0042802; GO:0070966; GO:0072344 28797 FUN_032160 4792 3479 2131 4725 2993 ptg000023l:29296180-29308966 Q3UJK4 2.76e-47 GTP-binding protein 2 (GTP-binding-like protein 2) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0006414; GO:0042802; GO:0070966; GO:0072344 28798 FUN_032160 4792 3479 2131 4725 2993 ptg000023l:29296180-29308966 Q3UJK4 1.29e-26 GTP-binding protein 2 (GTP-binding-like protein 2) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, no-go decay [GO:0070966]; rescue of stalled ribosome [GO:0072344]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0006414; GO:0042802; GO:0070966; GO:0072344 28799 FUN_032161 1573 755 648 980 903 NA NA NA NA NA NA NA 28800 FUN_043919 11 6 12 0 63 NA NA NA NA NA NA NA 28801 FUN_043918 1 1 4 8 13 NA NA NA NA NA NA NA 28802 FUN_008389 580 506 229 270 211 NA NA NA NA NA NA NA 28803 FUN_008388 1386 1132 556 1086 433 ptg000002l:11047740-11051708 Q9Z1N4 1.74e-59 3'(2'),5'-bisphosphate nucleotidase 1 (EC 3.1.3.7) (Bisphosphate 3'-nucleotidase 1) (PAP-inositol 1,4-phosphatase) (PIP) (scHAL2 analogous 3) Rattus norvegicus (Rat) inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] GO:0000287; GO:0004441; GO:0008441; GO:0046854; GO:0046855 28804 FUN_008383 7859 4081 3861 7089 4713 ptg000002l:11019950-11030714 Q4PE39 1.27e-31 Protein transport protein SEC23 Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) COPII-coated vesicle cargo loading [GO:0090110]; intracellular protein transport [GO:0006886] GO:0000139; GO:0005096; GO:0005789; GO:0006886; GO:0008270; GO:0030127; GO:0070971; GO:0090110 28805 FUN_008382 199 125 405 642 348 NA NA NA NA NA NA NA 28806 FUN_043915 34 56 0 0 0 NA NA NA NA NA NA NA 28807 FUN_043914 0 96 0 93 16 NA NA NA NA NA NA NA 28808 FUN_000153 3 0 4 0 12 ntLink_4:247960-248723 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28809 FUN_000150 7 0 7 0 96 ntLink_4:242021-243628 P35061 3.78e-80 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28810 FUN_000151 0 0 7 1 13 ntLink_4:243894-244657 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28811 FUN_005388 0 6 0 0 0 NA NA NA NA NA NA NA 28812 FUN_005389 569 321 289 480 717 NA NA NA NA NA NA NA 28813 FUN_000155 3 0 6 0 14 ntLink_4:252026-252789 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28814 FUN_005384 2199 2097 1119 2581 1725 NA NA NA NA NA NA NA 28815 FUN_005385 781 584 464 737 534 NA NA NA NA NA NA NA 28816 FUN_005387 3096 1605 2150 2832 3134 NA NA NA NA NA NA NA 28817 FUN_005380 1272 205 484 2546 283 ntLink_8:34612759-34618396 Q71U34 1.28e-98 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 28818 FUN_005380 1272 205 484 2546 283 ntLink_8:34612759-34618396 Q71U34 5.92e-36 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 28819 FUN_005380 1272 205 484 2546 283 ntLink_8:34612759-34618396 Q71U34 2.1e-21 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 28820 FUN_005380 1272 205 484 2546 283 ntLink_8:34612759-34618396 Q71U34 2.1e-21 Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) (Intracellular vitamin D-binding protein 1) Saguinus oedipus (Cotton-top tamarin) mRNA processing [GO:0006397]; RNA splicing [GO:0008380] GO:0005524; GO:0005681; GO:0005730; GO:0005886; GO:0006397; GO:0008380; GO:0042470; GO:0140662 28821 FUN_005381 0 10 0 16 91 ntLink_8:34626775-34668996 P63018 0 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 28822 FUN_005381 0 10 0 16 91 ntLink_8:34626775-34668996 P63018 2.57e-56 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 28823 FUN_005381 0 10 0 16 91 ntLink_8:34626775-34668996 P63018 2.57e-56 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 28824 FUN_005381 0 10 0 16 91 ntLink_8:34626775-34668996 P63018 2.57e-56 Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) Rattus norvegicus (Rat) aging [GO:0007568]; ATP metabolic process [GO:0046034]; axo-dendritic transport [GO:0008088]; cellular response to cadmium ion [GO:0071276]; cellular response to heat [GO:0034605]; cellular response to unfolded protein [GO:0034620]; cerebellum development [GO:0021549]; chaperone cofactor-dependent protein refolding [GO:0051085]; chaperone-mediated autophagy [GO:0061684]; chaperone-mediated autophagy translocation complex disassembly [GO:1904764]; chaperone-mediated protein folding [GO:0061077]; clathrin coat disassembly [GO:0072318]; estrous cycle [GO:0044849]; forebrain development [GO:0030900]; G1/S transition of mitotic cell cycle [GO:0000082]; kidney development [GO:0001822]; late endosomal microautophagy [GO:0061738]; maintenance of postsynaptic specialization structure [GO:0098880]; modulation by host of viral process [GO:0044788]; mRNA processing [GO:0006397]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of hydrogen peroxide-induced cell death [GO:1903206]; negative regulation of supramolecular fiber organization [GO:1902904]; positive regulation by host of viral genome replication [GO:0044829]; positive regulation of catalytic activity [GO:0043085]; positive regulation of gene expression [GO:0010628]; positive regulation of lysosomal membrane permeability [GO:0097214]; positive regulation of mRNA splicing, via spliceosome [GO:0048026]; positive regulation of phagocytosis [GO:0050766]; positive regulation of protein refolding [GO:1904592]; positive regulation of proteolysis [GO:0045862]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; protein autophosphorylation [GO:0046777]; protein folding [GO:0006457]; protein import into nucleus [GO:0006606]; protein refolding [GO:0042026]; protein targeting to lysosome involved in chaperone-mediated autophagy [GO:0061740]; protein transmembrane import into intracellular organelle [GO:0044743]; protein-containing complex disassembly [GO:0032984]; regulation of cell cycle [GO:0051726]; regulation of postsynapse organization [GO:0099175]; regulation of protein complex stability [GO:0061635]; regulation of protein stability [GO:0031647]; response to activity [GO:0014823]; response to estradiol [GO:0032355]; response to ethanol [GO:0045471]; response to heat [GO:0009408]; response to nickel cation [GO:0010045]; response to odorant [GO:1990834]; response to progesterone [GO:0032570]; response to starvation [GO:0042594]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sensory perception of smell [GO:0007608]; skeletal muscle tissue development [GO:0007519]; slow axonal transport [GO:1990832]; synaptic vesicle uncoating [GO:0016191]; vesicle-mediated transport [GO:0016192] GO:0000082; GO:0000974; GO:0001664; GO:0001786; GO:0001822; GO:0001916; GO:0001917; GO:0003723; GO:0005102; GO:0005524; GO:0005634; GO:0005681; GO:0005730; GO:0005737; GO:0005764; GO:0005765; GO:0005770; GO:0005776; GO:0005829; GO:0005874; GO:0005882; GO:0005886; GO:0006397; GO:0006457; GO:0006606; GO:0007519; GO:0007568; GO:0007608; GO:0008021; GO:0008088; GO:0008380; GO:0009408; GO:0009410; GO:0009986; GO:0010045; GO:0010628; GO:0010667; GO:0014069; GO:0014823; GO:0016191; GO:0016192; GO:0016887; GO:0019899; GO:0021549; GO:0030424; GO:0030425; GO:0030674; GO:0030900; GO:0031072; GO:0031625; GO:0031647; GO:0031686; GO:0032279; GO:0032355; GO:0032570; GO:0032984; GO:0032991; GO:0034605; GO:0034620; GO:0042026; GO:0042277; GO:0042470; GO:0042594; GO:0043005; GO:0043025; GO:0043085; GO:0043195; GO:0043197; GO:0043198; GO:0043202; GO:0043204; GO:0043531; GO:0044183; GO:0044309; GO:0044743; GO:0044788; GO:0044829; GO:0044849; GO:0045121; GO:0045471; GO:0045862; GO:0045892; GO:0046034; GO:0046777; GO:0048026; GO:0048471; GO:0050766; GO:0051082; GO:0051085; GO:0051087; GO:0051726; GO:0051787; GO:0055131; GO:0061077; GO:0061635; GO:0061684; GO:0061738; GO:0061740; GO:0070062; GO:0071276; GO:0072318; GO:0097214; GO:0098684; GO:0098690; GO:0098793; GO:0098794; GO:0098880; GO:0098978; GO:0099175; GO:0099523; GO:0099524; GO:0099634; GO:0101031; GO:0140545; GO:0140662; GO:1902904; GO:1903206; GO:1904592; GO:1904593; GO:1904764; GO:1990124; GO:1990832; GO:1990833; GO:1990834; GO:1990836; GO:1990904 28825 FUN_005382 415 110 112 381 235 NA NA NA NA NA NA NA 28826 FUN_005383 1089 1316 703 1183 1008 NA NA NA NA NA NA NA 28827 FUN_014209 26 18 0 4 97 NA NA NA NA NA NA NA 28828 FUN_044168 4 11 27 59 132 NA NA NA NA NA NA NA 28829 FUN_007728 0 0 0 0 6 NA NA NA NA NA NA NA 28830 FUN_007729 0 2 15 0 19 NA NA NA NA NA NA NA 28831 FUN_007724 0 275 1 0 0 NA NA NA NA NA NA NA 28832 FUN_007725 0 99 0 0 0 NA NA NA NA NA NA NA 28833 FUN_007726 0 18 0 0 0 NA NA NA NA NA NA NA 28834 FUN_007721 0 431 0 0 59 NA NA NA NA NA NA NA 28835 FUN_007723 0 35 0 0 0 NA NA NA NA NA NA NA 28836 FUN_032788 1538 1286 803 2232 1476 NA NA NA NA NA NA NA 28837 FUN_032789 250 244 128 260 238 NA NA NA NA NA NA NA 28838 FUN_032782 698 378 239 575 573 NA NA NA NA NA NA NA 28839 FUN_032783 170 135 128 179 169 NA NA NA NA NA NA NA 28840 FUN_032780 74 53 38 36 51 ptg000023l:35885568-35886642 P43141 1.72e-28 Beta-4C adrenergic receptor (Beta-4C adrenoreceptor) (Beta-4C adrenoceptor) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005886; GO:0007189; GO:0045823 28841 FUN_032781 268 207 280 407 387 NA NA NA NA NA NA NA 28842 FUN_032786 6 60 147 37 71 NA NA NA NA NA NA NA 28843 FUN_032787 216 524 241 874 762 NA NA NA NA NA NA NA 28844 FUN_032784 165 152 607 221 160 NA NA NA NA NA NA NA 28845 FUN_032785 204 133 334 128 97 NA NA NA NA NA NA NA 28846 FUN_013972 0 0 0 0 13 NA NA NA NA NA NA NA 28847 FUN_041456 82 402 74 182 503 NA NA NA NA NA NA NA 28848 FUN_044161 1 1 1 2 7 NA NA NA NA NA NA NA 28849 FUN_005659 0 0 7 0 1 NA NA NA NA NA NA NA 28850 FUN_044160 2 2 11 12 21 NA NA NA NA NA NA NA 28851 FUN_014206 0 0 3 0 29 NA NA NA NA NA NA NA 28852 FUN_044165 1 1 5 8 12 NA NA NA NA NA NA NA 28853 FUN_006899 2533 2041 1412 2915 1780 NA NA NA NA NA NA NA 28854 FUN_014204 0 6 0 11 23 NA NA NA NA NA NA NA 28855 FUN_006898 1661 618 729 1972 1947 NA NA NA NA NA NA NA 28856 FUN_029199 14052 17564 7575 7690 8140 NA NA NA NA NA NA NA 28857 FUN_029198 545 765 366 453 425 ptg000022l:9180076-9181252 Q1T7C0 5.36e-32 Centromere protein L (CENP-L) Gallus gallus (Chicken) NA GO:0000775; GO:0005634 28858 FUN_029193 1126 1822 1401 1704 1844 ptg000022l:9154312-9156897 A4IIA7 1.76e-34 S-adenosylmethionine sensor upstream of mTORC1 (Probable methyltransferase BMT2 homolog) (EC 2.1.1.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cellular response to amino acid starvation [GO:0034198]; methylation [GO:0032259]; negative regulation of TORC1 signaling [GO:1904262] GO:0008168; GO:0032259; GO:0034198; GO:1904047; GO:1904262 28859 FUN_029192 1180 557 761 601 1413 ptg000022l:9151955-9153998 Q7ZY86 1.05e-101 Transmembrane protein 168 Xenopus laevis (African clawed frog) NA GO:0017080; GO:0031965 28860 FUN_029191 137 408 143 202 291 ptg000022l:9149769-9151374 A7SNN9 5e-92 Queuosine salvage protein Nematostella vectensis (Starlet sea anemone) tRNA modification [GO:0006400]; tRNA-guanine transglycosylation [GO:0101030] GO:0006400; GO:0101030 28861 FUN_029191 137 408 143 202 291 ptg000022l:9149769-9151374 A7SNN9 1.86e-38 Queuosine salvage protein Nematostella vectensis (Starlet sea anemone) tRNA modification [GO:0006400]; tRNA-guanine transglycosylation [GO:0101030] GO:0006400; GO:0101030 28862 FUN_029190 1161 684 511 1024 978 NA NA NA NA NA NA NA 28863 FUN_029197 702 1031 570 1322 702 NA NA NA NA NA NA NA 28864 FUN_029196 274 191 113 73 168 NA NA NA NA NA NA NA 28865 FUN_029195 9583 7543 5078 6565 4172 NA NA NA NA NA NA NA 28866 FUN_029194 1034 977 248 455 379 NA NA NA NA NA NA NA 28867 FUN_033785 712 787 722 583 1163 ptg000024l:1326695-1328280 Q9BXS1 7.87e-42 Isopentenyl-diphosphate delta-isomerase 2 (EC 5.3.3.2) (Isopentenyl pyrophosphate isomerase 2) (IPP isomerase 2) (IPPI2) Homo sapiens (Human) cholesterol biosynthetic process [GO:0006695]; dimethylallyl diphosphate biosynthetic process [GO:0050992]; isopentenyl diphosphate biosynthetic process [GO:0009240]; isopentenyl diphosphate metabolic process [GO:0046490]; isoprenoid biosynthetic process [GO:0008299] GO:0004452; GO:0005737; GO:0005777; GO:0005829; GO:0006695; GO:0008299; GO:0009240; GO:0043231; GO:0046490; GO:0046872; GO:0050992 28868 FUN_033784 1697 1697 883 1273 1160 NA NA NA NA NA NA NA 28869 FUN_033787 4304 3329 1758 3238 2750 NA NA NA NA NA NA NA 28870 FUN_033786 698 594 399 611 575 NA NA NA NA NA NA NA 28871 FUN_033789 1665 1546 713 1254 1008 NA NA NA NA NA NA NA 28872 FUN_033788 24 14 160 40 25 NA NA NA NA NA NA NA 28873 FUN_001048 102 64 71 124 155 NA NA NA NA NA NA NA 28874 FUN_006892 32 61 60 0 35 NA NA NA NA NA NA NA 28875 FUN_000294 0 8 16 8 12 NA NA NA NA NA NA NA 28876 FUN_001042 3616 2486 2267 7 204 NA NA NA NA NA NA NA 28877 FUN_039238 10 0 73 20 263 NA NA NA NA NA NA NA 28878 FUN_040321 0 0 0 0 28 NA NA NA NA NA NA NA 28879 FUN_003711 1548 1237 880 924 981 NA NA NA NA NA NA NA 28880 FUN_003710 37 111 89 130 18 NA NA NA NA NA NA NA 28881 FUN_003713 9208 8027 2768 6634 5560 ntLink_8:14611810-14624727 A7RX69 7.02e-76 Metalloprotease TIKI homolog (EC 3.4.-.-) Nematostella vectensis (Starlet sea anemone) negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0016020; GO:0030178; GO:0046872 28882 FUN_003713 9208 8027 2768 6634 5560 ntLink_8:14611810-14624727 A7RX69 9.69e-29 Metalloprotease TIKI homolog (EC 3.4.-.-) Nematostella vectensis (Starlet sea anemone) negative regulation of Wnt signaling pathway [GO:0030178]; proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0016020; GO:0030178; GO:0046872 28883 FUN_003712 323 275 193 314 429 ntLink_8:14607159-14607417 P82921 1.16e-22 28S ribosomal protein S21, mitochondrial (MRP-S21) (S21mt) (Mitochondrial small ribosomal subunit protein bS21m) Homo sapiens (Human) mitochondrial translation [GO:0032543]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0005743; GO:0005763; GO:0006412; GO:0032543 28884 FUN_040329 1681 1180 920 2116 1767 NA NA NA NA NA NA NA 28885 FUN_007005 215 103 118 93 174 ptg000001l:19227418-19228031 Q9P2G9 2.14e-27 Kelch-like protein 8 Homo sapiens (Human) protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005654; GO:0006511; GO:0016567; GO:0031463 28886 FUN_003719 128 45 69 156 101 ntLink_8:14665340-14714330 P19477 1.83e-40 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 28887 FUN_003719 128 45 69 156 101 ntLink_8:14665340-14714330 P19477 1.84e-39 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 28888 FUN_003719 128 45 69 156 101 ntLink_8:14665340-14714330 P19477 8.3e-39 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 28889 FUN_003719 128 45 69 156 101 ntLink_8:14665340-14714330 P19477 5.18e-38 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 28890 FUN_003718 17217 15814 14131 17546 13766 ntLink_8:14650935-14661924 Q9NBX4 6.33e-23 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 28891 FUN_039233 84 11 6 59 12 NA NA NA NA NA NA NA 28892 FUN_034788 221 142 52 98 59 NA NA NA NA NA NA NA 28893 FUN_034789 179 160 70 83 78 NA NA NA NA NA NA NA 28894 FUN_034784 44 0 22 0 38 NA NA NA NA NA NA NA 28895 FUN_034785 870 1368 989 501 539 NA NA NA NA NA NA NA 28896 FUN_034786 49 48 14 99 91 NA NA NA NA NA NA NA 28897 FUN_034787 41 54 7 45 65 NA NA NA NA NA NA NA 28898 FUN_034780 19743 14700 9123 19659 19239 ptg000025l:126106-140014 Q9HGM3 5.92e-39 Mitochondrial respiratory chain complexes assembly protein rca1 (EC 3.4.24.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) mitochondrial protein processing [GO:0034982]; signal peptide processing [GO:0006465] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0005745; GO:0006465; GO:0008270; GO:0016887; GO:0034982 28899 FUN_034780 19743 14700 9123 19659 19239 ptg000025l:126106-140014 Q9HGM3 8.49e-22 Mitochondrial respiratory chain complexes assembly protein rca1 (EC 3.4.24.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) mitochondrial protein processing [GO:0034982]; signal peptide processing [GO:0006465] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0005745; GO:0006465; GO:0008270; GO:0016887; GO:0034982 28900 FUN_034780 19743 14700 9123 19659 19239 ptg000025l:126106-140014 Q9HGM3 8.49e-22 Mitochondrial respiratory chain complexes assembly protein rca1 (EC 3.4.24.-) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) mitochondrial protein processing [GO:0034982]; signal peptide processing [GO:0006465] GO:0004176; GO:0004222; GO:0005524; GO:0005739; GO:0005745; GO:0006465; GO:0008270; GO:0016887; GO:0034982 28901 FUN_034782 6 110 14 26 18 ptg000025l:159673-160048 P35067 9.66e-63 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 28902 FUN_034783 3038 1725 1571 2892 2854 ptg000025l:162423-175710 Q8TF05 4.21e-21 Serine/threonine-protein phosphatase 4 regulatory subunit 1 Homo sapiens (Human) protein dephosphorylation [GO:0006470]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0006468; GO:0006470; GO:0007165; GO:0019888; GO:0030289 28903 FUN_033513 213 4 0 0 184 NA NA NA NA NA NA NA 28904 FUN_028248 45 0 0 77 8 NA NA NA NA NA NA NA 28905 FUN_028249 45 20 0 28 47 NA NA NA NA NA NA NA 28906 FUN_028240 2117 867 223 1412 1094 NA NA NA NA NA NA NA 28907 FUN_028241 4109 2361 1631 2972 2553 NA NA NA NA NA NA NA 28908 FUN_028242 366 394 143 304 290 ptg000021l:17295034-17303390 P42893 6.46e-26 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 28909 FUN_028245 46 0 0 54 57 NA NA NA NA NA NA NA 28910 FUN_028246 236 240 53 194 72 NA NA NA NA NA NA NA 28911 FUN_028247 102 130 28 149 80 ptg000021l:17331855-17336847 Q86V71 6.77e-31 Zinc finger protein 429 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 28912 FUN_028247 102 130 28 149 80 ptg000021l:17331855-17336847 Q86V71 3.21e-26 Zinc finger protein 429 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 28913 FUN_028247 102 130 28 149 80 ptg000021l:17331855-17336847 Q86V71 3.69e-26 Zinc finger protein 429 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 28914 FUN_028247 102 130 28 149 80 ptg000021l:17331855-17336847 Q86V71 1.08e-25 Zinc finger protein 429 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 28915 FUN_028247 102 130 28 149 80 ptg000021l:17331855-17336847 Q86V71 1.17e-24 Zinc finger protein 429 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 28916 FUN_034256 7 0 0 22 0 NA NA NA NA NA NA NA 28917 FUN_034257 2817 2097 1813 5155 3588 NA NA NA NA NA NA NA 28918 FUN_034254 6 3 19 0 0 NA NA NA NA NA NA NA 28919 FUN_034255 0 0 0 0 9 NA NA NA NA NA NA NA 28920 FUN_034252 51 38 13 75 11 NA NA NA NA NA NA NA 28921 FUN_034253 288 198 240 626 47 NA NA NA NA NA NA NA 28922 FUN_034250 1634 1367 550 1044 408 NA NA NA NA NA NA NA 28923 FUN_034251 78 36 29 94 20 ptg000024l:6626626-6641335 Q95SX7 2.65e-31 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 28924 FUN_034251 78 36 29 94 20 ptg000024l:6626626-6641335 Q95SX7 2.65e-31 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 28925 FUN_034258 420 8 130 254 181 ptg000024l:6741789-6745113 Q66X05 3.42e-24 NACHT, LRR and PYD domains-containing protein 4F (NALP-kappa) Mus musculus (Mouse) actin filament organization [GO:0007015]; establishment of organelle localization [GO:0051656]; in utero embryonic development [GO:0001701]; inflammatory response [GO:0006954]; positive regulation of embryonic development [GO:0040019]; regulation of inflammatory response [GO:0050727] GO:0001701; GO:0005524; GO:0005737; GO:0005938; GO:0006954; GO:0007015; GO:0040019; GO:0050727; GO:0051656 28926 FUN_002582 484 343 841 674 352 NA NA NA NA NA NA NA 28927 FUN_037684 653 512 506 678 1027 ptg000026l:12317063-12325194 Q6GND3 1.76e-47 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A (EC 1.14.11.-) (Histone arginine demethylase JMJD6-A) (JmjC domain-containing protein 6-A) (Jumonji domain-containing protein 6-A) (Lysyl-hydroxylase JMJD6-A) (Peptide-lysine 5-dioxygenase JMJD6-A) (Phosphatidylserine receptor-A) (Protein PTDSR-A) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; protein homooligomerization [GO:0051260]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040] GO:0002040; GO:0003727; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006325; GO:0006397; GO:0008380; GO:0018395; GO:0030154; GO:0032452; GO:0033746; GO:0033749; GO:0046872; GO:0048024; GO:0051260; GO:0070815 28928 FUN_037684 653 512 506 678 1027 ptg000026l:12317063-12325194 Q6GND3 1.76e-47 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-A (EC 1.14.11.-) (Histone arginine demethylase JMJD6-A) (JmjC domain-containing protein 6-A) (Jumonji domain-containing protein 6-A) (Lysyl-hydroxylase JMJD6-A) (Peptide-lysine 5-dioxygenase JMJD6-A) (Phosphatidylserine receptor-A) (Protein PTDSR-A) Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; mRNA processing [GO:0006397]; peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine [GO:0018395]; protein homooligomerization [GO:0051260]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380]; sprouting angiogenesis [GO:0002040] GO:0002040; GO:0003727; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006325; GO:0006397; GO:0008380; GO:0018395; GO:0030154; GO:0032452; GO:0033746; GO:0033749; GO:0046872; GO:0048024; GO:0051260; GO:0070815 28929 FUN_002448 194 4 42 36 61 NA NA NA NA NA NA NA 28930 FUN_002449 103 41 26 53 49 NA NA NA NA NA NA NA 28931 FUN_037685 184 0 156 144 96 NA NA NA NA NA NA NA 28932 FUN_002442 24 8 141 11 53 NA NA NA NA NA NA NA 28933 FUN_002443 17 4 213 4 29 NA NA NA NA NA NA NA 28934 FUN_002440 151 0 130 21 274 NA NA NA NA NA NA NA 28935 FUN_002441 22 8 137 10 53 NA NA NA NA NA NA NA 28936 FUN_002446 31 24 89 0 0 NA NA NA NA NA NA NA 28937 FUN_002447 526 12 2 1025 4 NA NA NA NA NA NA NA 28938 FUN_002444 32 9 279 16 83 NA NA NA NA NA NA NA 28939 FUN_002445 39 18 112 26 38 NA NA NA NA NA NA NA 28940 FUN_012319 20 0 0 0 0 NA NA NA NA NA NA NA 28941 FUN_012318 0 34 0 41 0 NA NA NA NA NA NA NA 28942 FUN_012313 3 0 13 0 97 NA NA NA NA NA NA NA 28943 FUN_012312 0 63 61 312 116 NA NA NA NA NA NA NA 28944 FUN_012311 0 148 12 213 63 NA NA NA NA NA NA NA 28945 FUN_012310 3526 341 1002 2875 1199 NA NA NA NA NA NA NA 28946 FUN_012317 553 401 278 307 290 ptg000008l:7799214-7813044 H2LNR5 3.51e-37 Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) Oryzias latipes (Japanese rice fish) (Japanese killifish) cellular detoxification [GO:1990748]; cellular iron ion homeostasis [GO:0006879]; detoxification of zinc ion [GO:0010312]; iron-sulfur cluster assembly [GO:0016226]; iron-sulfur cluster export from the mitochondrion [GO:0140466]; negative regulation of reactive oxygen species biosynthetic process [GO:1903427]; positive regulation of heme biosynthetic process [GO:0070455]; transmembrane transport [GO:0055085] GO:0005524; GO:0005739; GO:0005743; GO:0006879; GO:0010312; GO:0016020; GO:0016226; GO:0016887; GO:0042626; GO:0055085; GO:0070455; GO:0140466; GO:0140481; GO:1903427; GO:1990748 28947 FUN_012316 4490 4971 2883 4555 2461 NA NA NA NA NA NA NA 28948 FUN_012315 3104 3480 2216 3573 1592 NA NA NA NA NA NA NA 28949 FUN_012314 26393 41578 12053 21021 2442 NA NA NA NA NA NA NA 28950 FUN_014418 33 0 0 0 15 NA NA NA NA NA NA NA 28951 FUN_014416 7 0 7 0 3 NA NA NA NA NA NA NA 28952 FUN_014415 3 1 4 9 21 NA NA NA NA NA NA NA 28953 FUN_014413 26 1 1 2 1 NA NA NA NA NA NA NA 28954 FUN_011469 94 65 30 27 0 NA NA NA NA NA NA NA 28955 FUN_043140 12 55 0 22 11 NA NA NA NA NA NA NA 28956 FUN_043142 5777 5645 3683 7784 3422 ptg000047l:4513862-4517014 B8EIZ7 1.11e-76 NA NA NA NA 28957 FUN_043143 877 626 501 314 363 ptg000047l:4517814-4533019 O01382 4.7e-31 Caspase (EC 3.4.22.-) (drICE) [Cleaved into: Caspase subunit p21; Caspase subunit p12] Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of peptidoglycan recognition protein signaling pathway [GO:0061060]; neuron remodeling [GO:0016322]; nurse cell apoptotic process [GO:0045476]; positive regulation of compound eye retinal cell programmed cell death [GO:0046672]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; programmed cell death [GO:0012501]; programmed cell death involved in cell development [GO:0010623]; proteolysis [GO:0006508]; response to X-ray [GO:0010165]; salivary gland histolysis [GO:0035070]; spermatid differentiation [GO:0048515] GO:0004197; GO:0005634; GO:0005737; GO:0005886; GO:0006508; GO:0006915; GO:0010165; GO:0010623; GO:0012501; GO:0016322; GO:0031625; GO:0035070; GO:0043066; GO:0045476; GO:0046672; GO:0048515; GO:0061060; GO:0097153; GO:0097200; GO:1990525; GO:2001269 28958 FUN_043143 877 626 501 314 363 ptg000047l:4517814-4533019 O01382 2.87e-28 Caspase (EC 3.4.22.-) (drICE) [Cleaved into: Caspase subunit p21; Caspase subunit p12] Drosophila melanogaster (Fruit fly) apoptotic process [GO:0006915]; negative regulation of apoptotic process [GO:0043066]; negative regulation of peptidoglycan recognition protein signaling pathway [GO:0061060]; neuron remodeling [GO:0016322]; nurse cell apoptotic process [GO:0045476]; positive regulation of compound eye retinal cell programmed cell death [GO:0046672]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; programmed cell death [GO:0012501]; programmed cell death involved in cell development [GO:0010623]; proteolysis [GO:0006508]; response to X-ray [GO:0010165]; salivary gland histolysis [GO:0035070]; spermatid differentiation [GO:0048515] GO:0004197; GO:0005634; GO:0005737; GO:0005886; GO:0006508; GO:0006915; GO:0010165; GO:0010623; GO:0012501; GO:0016322; GO:0031625; GO:0035070; GO:0043066; GO:0045476; GO:0046672; GO:0048515; GO:0061060; GO:0097153; GO:0097200; GO:1990525; GO:2001269 28959 FUN_011464 235 96 31 53 34 NA NA NA NA NA NA NA 28960 FUN_000962 1341 1323 602 1477 890 NA NA NA NA NA NA NA 28961 FUN_000961 2896 2034 1367 2237 1536 NA NA NA NA NA NA NA 28962 FUN_000960 3519 2353 1909 3899 2880 ntLink_6:6459817-6479715 P28271 2.52e-26 Cytoplasmic aconitate hydratase (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) (Iron regulatory protein 1) (IRP1) (Iron-responsive element-binding protein 1) (IRE-BP 1) Mus musculus (Mouse) cellular iron ion homeostasis [GO:0006879]; citrate metabolic process [GO:0006101]; intestinal absorption [GO:0050892]; post-embryonic development [GO:0009791]; regulation of gene expression [GO:0010468]; regulation of translation [GO:0006417]; response to iron(II) ion [GO:0010040]; tricarboxylic acid cycle [GO:0006099] GO:0003723; GO:0003994; GO:0005737; GO:0005739; GO:0005783; GO:0005794; GO:0005829; GO:0006099; GO:0006101; GO:0006417; GO:0006879; GO:0009791; GO:0010040; GO:0010468; GO:0030350; GO:0043231; GO:0046872; GO:0047780; GO:0048027; GO:0050892; GO:0051536; GO:0051538; GO:0051539 28963 FUN_000967 40 27 0 26 16 NA NA NA NA NA NA NA 28964 FUN_000966 13 9 2 27 15 NA NA NA NA NA NA NA 28965 FUN_000965 2092 929 1011 1546 1657 NA NA NA NA NA NA NA 28966 FUN_000964 642 423 295 506 550 NA NA NA NA NA NA NA 28967 FUN_000969 0 0 0 0 18 NA NA NA NA NA NA NA 28968 FUN_000968 9 0 0 25 13 ntLink_6:6578603-6582191 Q2QRV3 2.28e-24 Alpha-dioxygenase PIOX (EC 1.13.11.92) (Pathogen-induced oxygenase) Oryza sativa subsp. japonica (Rice) (R)-2-hydroxy-alpha-linolenic acid biosynthetic process [GO:1902609]; cell death [GO:0008219]; cellular response to nitric oxide [GO:0071732]; cellular response to reactive oxygen species [GO:0034614]; cellular response to salicylic acid stimulus [GO:0071446]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; fatty acid alpha-oxidation [GO:0001561]; oxylipin biosynthetic process [GO:0031408]; response to abscisic acid [GO:0009737]; systemic acquired resistance [GO:0009627] GO:0001561; GO:0004601; GO:0008219; GO:0009627; GO:0009737; GO:0012511; GO:0016702; GO:0020037; GO:0031408; GO:0034614; GO:0042742; GO:0046872; GO:0050832; GO:0071446; GO:0071732; GO:1902609 28969 FUN_009719 21 0 39 0 56 NA NA NA NA NA NA NA 28970 FUN_009718 0 40 107 0 0 NA NA NA NA NA NA NA 28971 FUN_009713 14 0 0 14 14 NA NA NA NA NA NA NA 28972 FUN_009712 200 138 105 251 296 NA NA NA NA NA NA NA 28973 FUN_009710 0 0 0 15 26 NA NA NA NA NA NA NA 28974 FUN_009717 112 123 201 73 22 NA NA NA NA NA NA NA 28975 FUN_009714 53 35 35 20 95 ptg000004l:10649133-10654523 Q96AY4 5.41e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28976 FUN_009714 53 35 35 20 95 ptg000004l:10649133-10654523 Q96AY4 4.93e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28977 FUN_009714 53 35 35 20 95 ptg000004l:10649133-10654523 Q96AY4 8.98e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 28978 FUN_035915 3275 4644 1406 3516 1626 NA NA NA NA NA NA NA 28979 FUN_029676 133 9 30 6 53 ptg000023l:4405119-4407288 E7FAM5 9.01e-62 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 28980 FUN_029677 105 0 52 91 108 NA NA NA NA NA NA NA 28981 FUN_029674 36 0 0 20 0 ptg000023l:4393279-4395444 E7FAM5 3.26e-51 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 28982 FUN_029675 2 0 84 2 51 NA NA NA NA NA NA NA 28983 FUN_029672 64 18 35 63 49 NA NA NA NA NA NA NA 28984 FUN_029673 2994 1129 1461 1446 1454 ptg000023l:4359440-4383252 Q07954 2.77e-34 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 28985 FUN_029673 2994 1129 1461 1446 1454 ptg000023l:4359440-4383252 Q07954 4.51e-26 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 28986 FUN_029673 2994 1129 1461 1446 1454 ptg000023l:4359440-4383252 Q07954 9.44e-23 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 28987 FUN_029673 2994 1129 1461 1446 1454 ptg000023l:4359440-4383252 Q07954 1.01e-21 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 28988 FUN_029670 9 3 9 15 6 ptg000023l:4337731-4338176 Q90YI8 6.64e-26 T-cell acute lymphocytic leukemia protein 1 (TAL-1) (FrSCL) (Stem cell protein) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; definitive hemopoiesis [GO:0060216]; endocardium formation [GO:0060214]; erythrocyte differentiation [GO:0030218]; hemangioblast cell differentiation [GO:0060217]; hematopoietic stem cell differentiation [GO:0060218]; myeloid cell differentiation [GO:0030099]; primitive hemopoiesis [GO:0060215]; vasculogenesis [GO:0001570] GO:0000981; GO:0001525; GO:0001570; GO:0003677; GO:0005634; GO:0030099; GO:0030218; GO:0046983; GO:0048844; GO:0060214; GO:0060215; GO:0060216; GO:0060217; GO:0060218 28989 FUN_029671 351 107 232 107 129 ptg000023l:4341384-4351489 Q8N3J2 1.76e-27 N(6)-adenine-specific methyltransferase METTL4 (Methyltransferase-like protein 4) (N(6)-adenine-specific DNA methyltransferase METTL4) (EC 2.1.1.72) (snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4) (EC 2.1.1.-) Homo sapiens (Human) chromatin organization [GO:0006325]; DNA methylation on adenine [GO:0032775]; regulation of chromatin organization [GO:1902275]; regulation of mitochondrial DNA replication [GO:0090296]; regulation of mitochondrial transcription [GO:1903108]; regulation of RNA splicing [GO:0043484]; snRNA (adenine-N6)-methylation [GO:0120049] GO:0003676; GO:0005634; GO:0005759; GO:0005829; GO:0006325; GO:0008168; GO:0008173; GO:0009007; GO:0032775; GO:0043484; GO:0090296; GO:0106347; GO:0120049; GO:1902275; GO:1903108 28990 FUN_029678 207 0 94 142 79 ptg000023l:4422325-4424497 E7FAM5 3.8e-58 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 28991 FUN_029679 31 90 1 55 5 NA NA NA NA NA NA NA 28992 FUN_016119 50 15 21 52 36 NA NA NA NA NA NA NA 28993 FUN_042238 850 1094 497 564 348 NA NA NA NA NA NA NA 28994 FUN_042231 0 0 6 0 3 NA NA NA NA NA NA NA 28995 FUN_016110 9731 6814 4881 12250 11533 NA NA NA NA NA NA NA 28996 FUN_016113 3060 3087 2217 4136 5528 NA NA NA NA NA NA NA 28997 FUN_042235 0 0 0 2 7 NA NA NA NA NA NA NA 28998 FUN_016117 41 34 23 75 64 NA NA NA NA NA NA NA 28999 FUN_042236 2 6 1 11 38 NA NA NA NA NA NA NA 29000 FUN_026529 452 70 112 303 340 NA NA NA NA NA NA NA 29001 FUN_026528 1236 856 536 873 803 ptg000020l:10143892-10152153 P79769 1.2e-26 Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO) Gallus gallus (Chicken) RNA metabolic process [GO:0016070] GO:0003697; GO:0003723; GO:0004519; GO:0005634; GO:0005737; GO:0016070; GO:0043565 29002 FUN_026523 0 0 0 15 9 NA NA NA NA NA NA NA 29003 FUN_026522 160 38 259 125 66 NA NA NA NA NA NA NA 29004 FUN_026521 60 0 17 12 120 NA NA NA NA NA NA NA 29005 FUN_026520 5 18 23 10 18 NA NA NA NA NA NA NA 29006 FUN_026527 261 520 327 219 236 ptg000020l:10094559-10141294 P79769 2.22e-23 Translin (EC 3.1.-.-) (Component 3 of promoter of RISC) (C3PO) Gallus gallus (Chicken) RNA metabolic process [GO:0016070] GO:0003697; GO:0003723; GO:0004519; GO:0005634; GO:0005737; GO:0016070; GO:0043565 29007 FUN_026526 4668 11 19 9753 626 NA NA NA NA NA NA NA 29008 FUN_026525 24 0 2 71 0 NA NA NA NA NA NA NA 29009 FUN_026524 0 0 11 14 27 NA NA NA NA NA NA NA 29010 FUN_022068 89 96 30 116 108 NA NA NA NA NA NA NA 29011 FUN_022069 211 112 29 117 96 ptg000016l:5209346-5211690 Q95ZJ1 6.85e-29 Polypeptide N-acetylgalactosaminyltransferase 5 (pp-GaNTase 5) (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 5) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5) Caenorhabditis elegans protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018243; GO:0030246; GO:0046872 29012 FUN_022060 0 0 7 11 2 NA NA NA NA NA NA NA 29013 FUN_022061 25 16 30 32 13 NA NA NA NA NA NA NA 29014 FUN_022066 7627 5396 4319 6877 4431 NA NA NA NA NA NA NA 29015 FUN_022067 354 153 251 364 363 NA NA NA NA NA NA NA 29016 FUN_022064 12 13 13 107 45 NA NA NA NA NA NA NA 29017 FUN_022065 0 0 22 25 36 NA NA NA NA NA NA NA 29018 FUN_017998 0 0 0 0 25 NA NA NA NA NA NA NA 29019 FUN_017999 36 187 57 114 873 NA NA NA NA NA NA NA 29020 FUN_017996 23 233 50 121 14 NA NA NA NA NA NA NA 29021 FUN_017997 0 35 0 5 0 NA NA NA NA NA NA NA 29022 FUN_017994 1982 1536 1820 917 503 NA NA NA NA NA NA NA 29023 FUN_017995 221 305 139 285 138 NA NA NA NA NA NA NA 29024 FUN_017992 9 5 1 3 3 NA NA NA NA NA NA NA 29025 FUN_017993 289 362 0 125 0 NA NA NA NA NA NA NA 29026 FUN_017990 13001 19032 16364 22845 12711 NA NA NA NA NA NA NA 29027 FUN_017991 123 121 75 126 159 ptg000012l:2846455-2866983 Q2KI24 1.59e-50 Methenyltetrahydrofolate synthase domain-containing protein Bos taurus (Bovine) NA GO:0003723; GO:0005737 29028 FUN_024969 0 0 0 0 6 NA NA NA NA NA NA NA 29029 FUN_024961 2 0 0 0 15 NA NA NA NA NA NA NA 29030 FUN_024963 2 0 0 0 6 NA NA NA NA NA NA NA 29031 FUN_024962 1 0 0 0 20 NA NA NA NA NA NA NA 29032 FUN_025382 0 0 747 0 553 NA NA NA NA NA NA NA 29033 FUN_025383 30 44 37 42 79 NA NA NA NA NA NA NA 29034 FUN_025380 0 0 244 0 259 NA NA NA NA NA NA NA 29035 FUN_025381 0 5 152 0 190 NA NA NA NA NA NA NA 29036 FUN_025386 0 0 38 0 89 ptg000019l:2144921-2147401 Q5F4A1 1.73e-49 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0046872 29037 FUN_025387 4 2 7 0 9 NA NA NA NA NA NA NA 29038 FUN_025384 0 41 47 0 37 NA NA NA NA NA NA NA 29039 FUN_025385 0 0 41 0 38 NA NA NA NA NA NA NA 29040 FUN_025388 0 0 136 0 114 NA NA NA NA NA NA NA 29041 FUN_025389 0 0 11 0 0 NA NA NA NA NA NA NA 29042 FUN_013394 60 62 141 209 79 ptg000008l:22039667-22040783 Q7ZVH1 1.68e-41 Membrane progestin receptor gamma-A (mPR gamma-A) (Progestin and adipoQ receptor family member V-A) Danio rerio (Zebrafish) (Brachydanio rerio) oogenesis [GO:0048477] GO:0005496; GO:0016020; GO:0038023; GO:0048477 29043 FUN_024389 1823 1187 1385 1287 1350 NA NA NA NA NA NA NA 29044 FUN_024388 3057 807 252 1897 1073 ptg000018l:5659212-5666669 Q7Z3G6 5.4e-25 Prickle-like protein 2 Homo sapiens (Human) Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0005737; GO:0008270; GO:0031965; GO:0060071 29045 FUN_024381 1105 641 625 590 307 NA NA NA NA NA NA NA 29046 FUN_024380 183 101 92 254 218 NA NA NA NA NA NA NA 29047 FUN_024383 3995 5025 2652 3790 1841 NA NA NA NA NA NA NA 29048 FUN_024382 1758 946 875 1274 1714 NA NA NA NA NA NA NA 29049 FUN_024385 2012 1294 1051 1711 1772 NA NA NA NA NA NA NA 29050 FUN_024384 1544 1749 1192 889 900 NA NA NA NA NA NA NA 29051 FUN_024387 1920 1590 662 1363 1517 NA NA NA NA NA NA NA 29052 FUN_024386 250 221 209 145 185 NA NA NA NA NA NA NA 29053 FUN_019459 4 0 4 3 7 NA NA NA NA NA NA NA 29054 FUN_019458 13 0 4 0 20 NA NA NA NA NA NA NA 29055 FUN_030038 2 1 18 16 35 NA NA NA NA NA NA NA 29056 FUN_030036 13 0 8 5 9 NA NA NA NA NA NA NA 29057 FUN_044305 0 0 0 0 7 NA NA NA NA NA NA NA 29058 FUN_030033 29 0 0 2 7 NA NA NA NA NA NA NA 29059 FUN_006231 431 164 143 217 193 ptg000001l:9559774-9564933 Q5SZK8 0 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023; GO:0070062 29060 FUN_006231 431 164 143 217 193 ptg000001l:9559774-9564933 Q5SZK8 6.34e-55 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023; GO:0070062 29061 FUN_006231 431 164 143 217 193 ptg000001l:9559774-9564933 Q5SZK8 5.22e-38 FRAS1-related extracellular matrix protein 2 (ECM3 homolog) Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; cell adhesion [GO:0007155]; cell communication [GO:0007154]; embryonic digit morphogenesis [GO:0042733]; eye development [GO:0001654]; heart development [GO:0007507]; inner ear development [GO:0048839]; kidney development [GO:0001822]; morphogenesis of an epithelium [GO:0002009] GO:0001654; GO:0001822; GO:0002009; GO:0005604; GO:0005886; GO:0007154; GO:0007155; GO:0007507; GO:0009653; GO:0042733; GO:0046872; GO:0048839; GO:0062023; GO:0070062 29062 FUN_038209 68 61 104 121 44 ptg000027l:4206034-4209852 H2LRU7 1.35e-41 Polycystin-2 (Polycystic kidney disease 2 protein homolog) Oryzias latipes (Japanese rice fish) (Japanese killifish) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; detection of nodal flow [GO:0003127]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0003127; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005789; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 29063 FUN_042072 0 19 0 0 0 NA NA NA NA NA NA NA 29064 FUN_038205 605 496 413 108 595 NA NA NA NA NA NA NA 29065 FUN_038204 12201 7511 6952 12396 12123 NA NA NA NA NA NA NA 29066 FUN_038207 13 0 0 12 0 NA NA NA NA NA NA NA 29067 FUN_038206 13 0 0 0 0 NA NA NA NA NA NA NA 29068 FUN_038201 317 842 316 601 326 NA NA NA NA NA NA NA 29069 FUN_042071 16 239 8 22 16 ptg000036l:239717-245371 Q96MM6 3.42e-60 Heat shock 70 kDa protein 12B Homo sapiens (Human) NA GO:0005524 29070 FUN_038203 1384 2589 1134 1563 1076 NA NA NA NA NA NA NA 29071 FUN_039552 0 0 1 0 7 NA NA NA NA NA NA NA 29072 FUN_039553 0 0 11 0 10 NA NA NA NA NA NA NA 29073 FUN_039556 42 34 20 53 45 NA NA NA NA NA NA NA 29074 FUN_039557 529 656 611 539 749 NA NA NA NA NA NA NA 29075 FUN_039555 19 29 26 21 238 NA NA NA NA NA NA NA 29076 FUN_039558 188 243 66 487 91 NA NA NA NA NA NA NA 29077 FUN_039559 153 31 117 172 463 NA NA NA NA NA NA NA 29078 FUN_024033 3 34 7 0 12 NA NA NA NA NA NA NA 29079 FUN_024032 220 48 132 132 136 ptg000018l:1520455-1533067 O14746 2.69e-25 Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; DNA biosynthetic process [GO:0071897]; DNA strand elongation [GO:0022616]; establishment of protein localization to telomere [GO:0070200]; mitochondrion organization [GO:0007005]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of miRNA maturation [GO:1903799]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of angiogenesis [GO:0045766]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glucose import [GO:0046326]; positive regulation of hair cycle [GO:0042635]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transdifferentiation [GO:1903620]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of protein stability [GO:0031647]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; RNA-templated DNA biosynthetic process [GO:0006278]; RNA-templated transcription [GO:0001172]; siRNA processing [GO:0030422]; siRNA transcription [GO:0140745]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] GO:0000049; GO:0000333; GO:0000723; GO:0000781; GO:0000783; GO:0001172; GO:0001223; GO:0003677; GO:0003720; GO:0003721; GO:0003723; GO:0003964; GO:0003968; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0005829; GO:0005886; GO:0006278; GO:0007004; GO:0007005; GO:0008022; GO:0010629; GO:0016605; GO:0016607; GO:0022616; GO:0030177; GO:0030422; GO:0031379; GO:0031647; GO:0032092; GO:0042162; GO:0042635; GO:0042645; GO:0042802; GO:0042803; GO:0043524; GO:0045766; GO:0046326; GO:0046686; GO:0046872; GO:0047485; GO:0051000; GO:0051087; GO:0070034; GO:0070200; GO:0071456; GO:0071897; GO:0090399; GO:0098680; GO:0140745; GO:1900087; GO:1902895; GO:1903620; GO:1903799; GO:1904707; GO:1904751; GO:1904754; GO:1990572; GO:2000352; GO:2000648; GO:2000773; GO:2001240 29080 FUN_024032 220 48 132 132 136 ptg000018l:1520455-1533067 O14746 3.19e-25 Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; DNA biosynthetic process [GO:0071897]; DNA strand elongation [GO:0022616]; establishment of protein localization to telomere [GO:0070200]; mitochondrion organization [GO:0007005]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of miRNA maturation [GO:1903799]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of angiogenesis [GO:0045766]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glucose import [GO:0046326]; positive regulation of hair cycle [GO:0042635]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transdifferentiation [GO:1903620]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of protein stability [GO:0031647]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; RNA-templated DNA biosynthetic process [GO:0006278]; RNA-templated transcription [GO:0001172]; siRNA processing [GO:0030422]; siRNA transcription [GO:0140745]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] GO:0000049; GO:0000333; GO:0000723; GO:0000781; GO:0000783; GO:0001172; GO:0001223; GO:0003677; GO:0003720; GO:0003721; GO:0003723; GO:0003964; GO:0003968; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0005829; GO:0005886; GO:0006278; GO:0007004; GO:0007005; GO:0008022; GO:0010629; GO:0016605; GO:0016607; GO:0022616; GO:0030177; GO:0030422; GO:0031379; GO:0031647; GO:0032092; GO:0042162; GO:0042635; GO:0042645; GO:0042802; GO:0042803; GO:0043524; GO:0045766; GO:0046326; GO:0046686; GO:0046872; GO:0047485; GO:0051000; GO:0051087; GO:0070034; GO:0070200; GO:0071456; GO:0071897; GO:0090399; GO:0098680; GO:0140745; GO:1900087; GO:1902895; GO:1903620; GO:1903799; GO:1904707; GO:1904751; GO:1904754; GO:1990572; GO:2000352; GO:2000648; GO:2000773; GO:2001240 29081 FUN_024032 220 48 132 132 136 ptg000018l:1520455-1533067 O14746 1.28e-22 Telomerase reverse transcriptase (EC 2.7.7.49) (HEST2) (Telomerase catalytic subunit) (Telomerase-associated protein 2) (TP2) Homo sapiens (Human) cellular response to hypoxia [GO:0071456]; DNA biosynthetic process [GO:0071897]; DNA strand elongation [GO:0022616]; establishment of protein localization to telomere [GO:0070200]; mitochondrion organization [GO:0007005]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of miRNA maturation [GO:1903799]; negative regulation of neuron apoptotic process [GO:0043524]; positive regulation of angiogenesis [GO:0045766]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of glucose import [GO:0046326]; positive regulation of hair cycle [GO:0042635]; positive regulation of miRNA transcription [GO:1902895]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to nucleolus [GO:1904751]; positive regulation of stem cell proliferation [GO:2000648]; positive regulation of transdifferentiation [GO:1903620]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of protein stability [GO:0031647]; replicative senescence [GO:0090399]; response to cadmium ion [GO:0046686]; RNA-templated DNA biosynthetic process [GO:0006278]; RNA-templated transcription [GO:0001172]; siRNA processing [GO:0030422]; siRNA transcription [GO:0140745]; telomere maintenance [GO:0000723]; telomere maintenance via telomerase [GO:0007004] GO:0000049; GO:0000333; GO:0000723; GO:0000781; GO:0000783; GO:0001172; GO:0001223; GO:0003677; GO:0003720; GO:0003721; GO:0003723; GO:0003964; GO:0003968; GO:0005634; GO:0005654; GO:0005697; GO:0005730; GO:0005829; GO:0005886; GO:0006278; GO:0007004; GO:0007005; GO:0008022; GO:0010629; GO:0016605; GO:0016607; GO:0022616; GO:0030177; GO:0030422; GO:0031379; GO:0031647; GO:0032092; GO:0042162; GO:0042635; GO:0042645; GO:0042802; GO:0042803; GO:0043524; GO:0045766; GO:0046326; GO:0046686; GO:0046872; GO:0047485; GO:0051000; GO:0051087; GO:0070034; GO:0070200; GO:0071456; GO:0071897; GO:0090399; GO:0098680; GO:0140745; GO:1900087; GO:1902895; GO:1903620; GO:1903799; GO:1904707; GO:1904751; GO:1904754; GO:1990572; GO:2000352; GO:2000648; GO:2000773; GO:2001240 29082 FUN_024031 1193 758 615 1388 1324 NA NA NA NA NA NA NA 29083 FUN_024030 1054 747 550 1443 1081 ptg000018l:1490768-1505541 Q8BW94 3.18e-23 Dynein axonemal heavy chain 3 (Axonemal beta dynein heavy chain 3) (Ciliary dynein heavy chain 3) Mus musculus (Mouse) cilium movement [GO:0003341]; microtubule-based movement [GO:0007018] GO:0003341; GO:0005524; GO:0005874; GO:0007018; GO:0008569; GO:0030286; GO:0036156; GO:0045505; GO:0051959; GO:0097729 29084 FUN_024037 624 500 349 410 624 NA NA NA NA NA NA NA 29085 FUN_024036 1810 1257 970 1068 436 ptg000018l:1571717-1573298 P69478 4.3e-39 Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; carbohydrate biosynthetic process [GO:0016051]; cartilage development [GO:0051216]; chondrocyte development [GO:0002063]; chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate metabolic process [GO:0030204]; developmental growth [GO:0048589]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; embryonic skeletal system morphogenesis [GO:0048704]; embryonic viscerocranium morphogenesis [GO:0048703]; in utero embryonic development [GO:0001701]; negative regulation of apoptotic process [GO:0043066]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; polysaccharide localization [GO:0033037]; post-anal tail morphogenesis [GO:0036342]; post-embryonic development [GO:0009791]; proteoglycan biosynthetic process [GO:0030166]; regulation of cell population proliferation [GO:0042127]; respiratory gaseous exchange by respiratory system [GO:0007585]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0001537; GO:0001701; GO:0002063; GO:0006915; GO:0007179; GO:0007585; GO:0008146; GO:0009791; GO:0016051; GO:0030166; GO:0030204; GO:0030206; GO:0030326; GO:0030512; GO:0033037; GO:0036342; GO:0042127; GO:0042733; GO:0043066; GO:0047756; GO:0048589; GO:0048703; GO:0048704; GO:0050659; GO:0051216 29086 FUN_024035 1927 1464 1030 2024 1076 ptg000018l:1554549-1564269 E9PU28 6.09e-46 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Rattus norvegicus (Rat) 'de novo' XMP biosynthetic process [GO:0097294]; cellular response to interleukin-4 [GO:0071353]; circadian rhythm [GO:0007623]; GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; retina development in camera-type eye [GO:0060041] GO:0000166; GO:0003938; GO:0005634; GO:0005737; GO:0005829; GO:0006164; GO:0006177; GO:0006183; GO:0007623; GO:0042802; GO:0046651; GO:0046872; GO:0060041; GO:0071353; GO:0097294 29087 FUN_024035 1927 1464 1030 2024 1076 ptg000018l:1554549-1564269 E9PU28 6.22e-22 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Rattus norvegicus (Rat) 'de novo' XMP biosynthetic process [GO:0097294]; cellular response to interleukin-4 [GO:0071353]; circadian rhythm [GO:0007623]; GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183]; lymphocyte proliferation [GO:0046651]; purine nucleotide biosynthetic process [GO:0006164]; retina development in camera-type eye [GO:0060041] GO:0000166; GO:0003938; GO:0005634; GO:0005737; GO:0005829; GO:0006164; GO:0006177; GO:0006183; GO:0007623; GO:0042802; GO:0046651; GO:0046872; GO:0060041; GO:0071353; GO:0097294 29088 FUN_024034 24695 19356 12031 18841 13444 ptg000018l:1541225-1551986 P30682 4.9e-31 Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188] GO:0003924; GO:0005525; GO:0007188; GO:0031683; GO:0046872; GO:0110165 29089 FUN_024034 24695 19356 12031 18841 13444 ptg000018l:1541225-1551986 P30682 2.37e-21 Guanine nucleotide-binding protein G(i) subunit alpha (Adenylate cyclase-inhibiting G alpha protein) Lymnaea stagnalis (Great pond snail) (Helix stagnalis) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188] GO:0003924; GO:0005525; GO:0007188; GO:0031683; GO:0046872; GO:0110165 29090 FUN_024039 194 0 0 221 3 NA NA NA NA NA NA NA 29091 FUN_024038 97 21 4 55 24 NA NA NA NA NA NA NA 29092 FUN_027609 79 680 248 89 64 NA NA NA NA NA NA NA 29093 FUN_027608 0 355 0 0 21 NA NA NA NA NA NA NA 29094 FUN_027605 0 10 0 1 5 NA NA NA NA NA NA NA 29095 FUN_027607 8 0 0 0 0 NA NA NA NA NA NA NA 29096 FUN_027606 0 13 7 3 25 NA NA NA NA NA NA NA 29097 FUN_027601 263 92 61 165 89 NA NA NA NA NA NA NA 29098 FUN_027603 7 2 25 8 23 NA NA NA NA NA NA NA 29099 FUN_027602 91 26 5 0 0 NA NA NA NA NA NA NA 29100 FUN_013391 602 198 840 580 421 NA NA NA NA NA NA NA 29101 FUN_031789 4935 4882 2346 4733 3956 NA NA NA NA NA NA NA 29102 FUN_031787 3267 3453 1914 2904 2657 NA NA NA NA NA NA NA 29103 FUN_031786 25 100 136 26 93 NA NA NA NA NA NA NA 29104 FUN_031785 4744 3281 3453 6265 6311 ptg000023l:25408410-25415636 Q9ULT8 1.51e-31 E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1) Homo sapiens (Human) anatomical structure development [GO:0048856]; aorta development [GO:0035904]; heart valve development [GO:0003170]; natural killer cell differentiation [GO:0001779]; negative regulation of protein localization to plasma membrane [GO:1903077]; neural tube closure [GO:0001843]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein localization to plasma membrane [GO:0072659]; protein polyubiquitination [GO:0000209]; spongiotrophoblast differentiation [GO:0060708]; trophoblast giant cell differentiation [GO:0060707]; ventricular septum development [GO:0003281] GO:0000209; GO:0001779; GO:0001843; GO:0003170; GO:0003281; GO:0016607; GO:0032436; GO:0035904; GO:0043161; GO:0046872; GO:0048856; GO:0051865; GO:0060707; GO:0060708; GO:0061630; GO:0070534; GO:0072659; GO:1903077 29105 FUN_031784 130 89 151 179 227 NA NA NA NA NA NA NA 29106 FUN_031783 411 432 305 308 328 NA NA NA NA NA NA NA 29107 FUN_031782 176657 175905 70924 173850 62494 NA NA NA NA NA NA NA 29108 FUN_031781 66 95 39 37 29 NA NA NA NA NA NA NA 29109 FUN_031780 45 59 30 75 33 NA NA NA NA NA NA NA 29110 FUN_036067 25 46 0 40 24 NA NA NA NA NA NA NA 29111 FUN_036066 184 416 52 165 97 NA NA NA NA NA NA NA 29112 FUN_036065 130 113 19 101 21 NA NA NA NA NA NA NA 29113 FUN_036064 525 380 315 450 162 NA NA NA NA NA NA NA 29114 FUN_036063 0 8 14 66 31 NA NA NA NA NA NA NA 29115 FUN_036062 3 0 13 15 6 NA NA NA NA NA NA NA 29116 FUN_036061 24 26 20 26 11 NA NA NA NA NA NA NA 29117 FUN_036060 227 448 132 358 233 NA NA NA NA NA NA NA 29118 FUN_024368 1633 1167 784 1258 915 ptg000018l:5474709-5487761 Q4R628 1.98e-29 Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) centriole-centriole cohesion [GO:0010457]; cilium assembly [GO:0060271]; microtubule anchoring at centrosome [GO:0034454]; microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007018; GO:0008017; GO:0010457; GO:0034454; GO:0060271 29119 FUN_036069 93 163 19 205 63 NA NA NA NA NA NA NA 29120 FUN_036068 0 34 22 27 24 NA NA NA NA NA NA NA 29121 FUN_037334 28 20 58 0 22 NA NA NA NA NA NA NA 29122 FUN_037335 5927 1916 1216 4404 1551 NA NA NA NA NA NA NA 29123 FUN_037336 816 438 493 1104 520 NA NA NA NA NA NA NA 29124 FUN_037337 11 19 0 17 41 NA NA NA NA NA NA NA 29125 FUN_037330 507 345 88 441 242 NA NA NA NA NA NA NA 29126 FUN_037331 7087 4098 2888 8798 6414 NA NA NA NA NA NA NA 29127 FUN_037332 1364 744 650 1640 1254 NA NA NA NA NA NA NA 29128 FUN_037333 4413 2811 1615 4469 2771 NA NA NA NA NA NA NA 29129 FUN_037339 440 0 0 0 169 NA NA NA NA NA NA NA 29130 FUN_006036 0 0 18 0 26 NA NA NA NA NA NA NA 29131 FUN_006031 20 0 12 0 67 NA NA NA NA NA NA NA 29132 FUN_006039 74 53 44 88 183 NA NA NA NA NA NA NA 29133 FUN_006038 5426 2369 1760 4330 1806 NA NA NA NA NA NA NA 29134 FUN_026952 36 0 38 0 240 NA NA NA NA NA NA NA 29135 FUN_026951 53 0 17 0 237 NA NA NA NA NA NA NA 29136 FUN_026956 0 0 0 0 8 NA NA NA NA NA NA NA 29137 FUN_018530 43287 31157 23899 45854 33748 ptg000012l:10490278-10531212 Q62261 5.42e-46 Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Embryonic liver fodrin) (Fodrin beta chain) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament capping [GO:0051693]; central nervous system development [GO:0007417]; central nervous system formation [GO:0021556]; common-partner SMAD protein phosphorylation [GO:0007182]; Golgi to plasma membrane protein transport [GO:0043001]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; plasma membrane organization [GO:0007009]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to plasma membrane [GO:0072659]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of SMAD protein signal transduction [GO:0060390] GO:0000281; GO:0005200; GO:0005516; GO:0005543; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0005886; GO:0007009; GO:0007182; GO:0007417; GO:0008091; GO:0012505; GO:0014069; GO:0016020; GO:0021556; GO:0030036; GO:0030054; GO:0030506; GO:0030673; GO:0030863; GO:0030864; GO:0031430; GO:0032437; GO:0032743; GO:0032991; GO:0042995; GO:0043001; GO:0044877; GO:0051015; GO:0051020; GO:0051693; GO:0060390; GO:0071709; GO:0072659; GO:0098794; GO:0098978; GO:1903076; GO:1903078 29138 FUN_030319 8 1 4 0 19 ptg000023l:10600420-10601183 P84239 1.14e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 29139 FUN_008567 54 63 31 45 59 NA NA NA NA NA NA NA 29140 FUN_008566 332 92 225 251 448 NA NA NA NA NA NA NA 29141 FUN_006501 137 21 77 282 44 NA NA NA NA NA NA NA 29142 FUN_033986 8235 2916 2531 3263 2965 NA NA NA NA NA NA NA 29143 FUN_008564 279 240 237 122 151 NA NA NA NA NA NA NA 29144 FUN_006506 0 8 0 0 0 NA NA NA NA NA NA NA 29145 FUN_008561 719 1932 747 1042 405 NA NA NA NA NA NA NA 29146 FUN_005414 0 0 2 2 8 NA NA NA NA NA NA NA 29147 FUN_005411 0 0 0 0 6 NA NA NA NA NA NA NA 29148 FUN_005412 6 0 0 0 11 NA NA NA NA NA NA NA 29149 FUN_005418 161 74 0 4 17 NA NA NA NA NA NA NA 29150 FUN_001564 0 32 0 0 6 NA NA NA NA NA NA NA 29151 FUN_001565 9 0 29 0 112 NA NA NA NA NA NA NA 29152 FUN_001567 0 0 0 33 0 NA NA NA NA NA NA NA 29153 FUN_001560 0 0 1 0 8 NA NA NA NA NA NA NA 29154 FUN_001562 5707 4290 3489 6428 5427 ntLink_6:13745846-13776639 Q8IWZ3 8.89e-55 Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK) Homo sapiens (Human) innate immune response [GO:0045087] GO:0003723; GO:0005737; GO:0045087 29155 FUN_001562 5707 4290 3489 6428 5427 ntLink_6:13745846-13776639 Q8IWZ3 2.74e-50 Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK) Homo sapiens (Human) innate immune response [GO:0045087] GO:0003723; GO:0005737; GO:0045087 29156 FUN_001562 5707 4290 3489 6428 5427 ntLink_6:13745846-13776639 Q8IWZ3 1.84e-33 Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK) Homo sapiens (Human) innate immune response [GO:0045087] GO:0003723; GO:0005737; GO:0045087 29157 FUN_001562 5707 4290 3489 6428 5427 ntLink_6:13745846-13776639 Q8IWZ3 3.53e-25 Ankyrin repeat and KH domain-containing protein 1 (HIV-1 Vpr-binding ankyrin repeat protein) (Multiple ankyrin repeats single KH domain) (hMASK) Homo sapiens (Human) innate immune response [GO:0045087] GO:0003723; GO:0005737; GO:0045087 29158 FUN_006807 14 8 354 5079 1920 NA NA NA NA NA NA NA 29159 FUN_001569 0 9 0 0 10 NA NA NA NA NA NA NA 29160 FUN_016523 42 44 60 608 49 ptg000011l:4335762-4340809 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29161 FUN_016523 42 44 60 608 49 ptg000011l:4335762-4340809 Q96AY4 1.37e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29162 FUN_016523 42 44 60 608 49 ptg000011l:4335762-4340809 Q96AY4 6.01e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29163 FUN_016523 42 44 60 608 49 ptg000011l:4335762-4340809 Q96AY4 4.71e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29164 FUN_006803 1147 481 512 860 694 NA NA NA NA NA NA NA 29165 FUN_025242 14 0 0 23 20 NA NA NA NA NA NA NA 29166 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 9.69e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29167 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 1.62e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29168 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 2e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29169 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 2.14e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29170 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 9.19e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29171 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 3.27e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29172 FUN_016527 5 25 4 133 17 ptg000011l:4384931-4388769 Q96AY4 5.49e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29173 FUN_026324 50 7 4 0 3 NA NA NA NA NA NA NA 29174 FUN_033545 0 2 12 0 95 NA NA NA NA NA NA NA 29175 FUN_033542 0 0 0 8 0 NA NA NA NA NA NA NA 29176 FUN_016609 149 311 93 327 213 NA NA NA NA NA NA NA 29177 FUN_033549 0 0 0 0 8 NA NA NA NA NA NA NA 29178 FUN_023970 895 1236 588 1049 615 NA NA NA NA NA NA NA 29179 FUN_035748 1650 1014 1142 1834 1432 ptg000025l:11279836-11288009 Q9P2E3 0 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29180 FUN_035748 1650 1014 1142 1834 1432 ptg000025l:11279836-11288009 Q9P2E3 1.1e-66 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29181 FUN_035748 1650 1014 1142 1834 1432 ptg000025l:11279836-11288009 Q9P2E3 1.75e-64 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 29182 FUN_023977 743 217 94 886 284 NA NA NA NA NA NA NA 29183 FUN_023976 760 255 257 1264 920 NA NA NA NA NA NA NA 29184 FUN_004615 18 16 35 26 8 NA NA NA NA NA NA NA 29185 FUN_040016 637 464 394 367 337 ptg000031l:3000364-3008291 Q8C1B2 1.29e-27 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 29186 FUN_013353 0 0 0 46 11 NA NA NA NA NA NA NA 29187 FUN_040015 751 729 448 1136 715 ptg000031l:2992310-2996566 Q8C1B2 1.71e-26 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 29188 FUN_018193 522 229 330 265 513 NA NA NA NA NA NA NA 29189 FUN_018197 35 0 49 18 46 NA NA NA NA NA NA NA 29190 FUN_018196 1050 63 943 364 722 NA NA NA NA NA NA NA 29191 FUN_007816 1300 492 354 381 214 ptg000002l:5037588-5041314 Q9Y6A2 1.17e-33 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 29192 FUN_007816 1300 492 354 381 214 ptg000002l:5037588-5041314 Q9Y6A2 2.88e-23 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; cholesterol catabolic process [GO:0006707]; nervous system development [GO:0007399]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; sterol metabolic process [GO:0016125]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005783; GO:0005789; GO:0006699; GO:0006707; GO:0006805; GO:0007399; GO:0008395; GO:0016125; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 29193 FUN_018198 84 0 98 17 15 NA NA NA NA NA NA NA 29194 FUN_007812 86 41 53 102 20 NA NA NA NA NA NA NA 29195 FUN_023979 536 402 412 732 371 NA NA NA NA NA NA NA 29196 FUN_007810 282 368 40 58 40 NA NA NA NA NA NA NA 29197 FUN_023978 2083 634 707 3009 1548 NA NA NA NA NA NA NA 29198 FUN_040010 87 42 20 75 63 NA NA NA NA NA NA NA 29199 FUN_034015 4273 3272 1352 1845 1055 NA NA NA NA NA NA NA 29200 FUN_034016 2740 3039 1459 2018 879 NA NA NA NA NA NA NA 29201 FUN_034017 687 781 422 601 383 NA NA NA NA NA NA NA 29202 FUN_034010 1423 1136 858 1109 1274 NA NA NA NA NA NA NA 29203 FUN_034012 1187 686 759 1360 1109 ptg000024l:3690682-3706210 B1AQJ2 6.12e-24 Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) Mus musculus (Mouse) histone deubiquitination [GO:0016578]; negative regulation of macroautophagy [GO:0016242]; nucleolus organization [GO:0007000]; protein deubiquitination [GO:0016579]; protein stabilization [GO:0050821]; regulation of apoptotic process [GO:0042981]; regulation of protein stability [GO:0031647]; regulation of rRNA processing [GO:2000232]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006511; GO:0007000; GO:0016242; GO:0016578; GO:0016579; GO:0016607; GO:0031647; GO:0042981; GO:0050821; GO:2000232 29204 FUN_018449 1090 235 563 299 1127 NA NA NA NA NA NA NA 29205 FUN_034019 318 223 165 172 115 ptg000024l:3761415-3764199 Q8C8H8 2.44e-24 Kyphoscoliosis peptidase (EC 3.4.-.-) Mus musculus (Mouse) muscle organ development [GO:0007517]; neuromuscular junction development [GO:0007528]; proteolysis [GO:0006508] GO:0005737; GO:0005856; GO:0006508; GO:0007517; GO:0007528; GO:0008233; GO:0030018 29206 FUN_026322 124 11 8 0 4 NA NA NA NA NA NA NA 29207 FUN_035742 14419 21785 15305 13247 11174 NA NA NA NA NA NA NA 29208 FUN_007108 72 0 0 0 29 NA NA NA NA NA NA NA 29209 FUN_007109 6 1 2 1 35 NA NA NA NA NA NA NA 29210 FUN_043308 0 18 0 29 0 NA NA NA NA NA NA NA 29211 FUN_043309 1446 1093 799 896 1341 ptg000047l:6843667-6867750 Q8TDW7 4.8e-26 Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3) Homo sapiens (Human) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29212 FUN_043309 1446 1093 799 896 1341 ptg000047l:6843667-6867750 Q8TDW7 6.32e-25 Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3) Homo sapiens (Human) cell morphogenesis involved in differentiation [GO:0000904]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; interneuron migration [GO:1904936]; negative regulation of dendrite development [GO:2000171]; retina layer formation [GO:0010842] GO:0000904; GO:0005509; GO:0005886; GO:0007156; GO:0010842; GO:0016358; GO:0030425; GO:0098609; GO:1904936; GO:2000171 29213 FUN_043306 339 496 180 4 423 NA NA NA NA NA NA NA 29214 FUN_043307 117 409 16 68 300 NA NA NA NA NA NA NA 29215 FUN_043304 262 355 248 318 191 NA NA NA NA NA NA NA 29216 FUN_007107 28 0 0 0 0 NA NA NA NA NA NA NA 29217 FUN_043302 1495 1052 617 808 527 NA NA NA NA NA NA NA 29218 FUN_007101 251 66 212 266 336 ptg000001l:20492013-20508659 Q2PZL6 1.62e-25 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 29219 FUN_007101 251 66 212 266 336 ptg000001l:20492013-20508659 Q2PZL6 3.67e-24 Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; cell-cell adhesion [GO:0098609]; cerebral cortex development [GO:0021987]; condensed mesenchymal cell proliferation [GO:0072137]; digestive tract development [GO:0048565]; establishment of planar polarity [GO:0001736]; fibroblast growth factor receptor signaling pathway [GO:0008543]; heart morphogenesis [GO:0003007]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; hippo signaling [GO:0035329]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; inner ear receptor cell stereocilium organization [GO:0060122]; kidney development [GO:0001822]; nephron development [GO:0072006]; neurogenesis [GO:0022008]; Notch signaling pathway [GO:0007219]; ossification involved in bone maturation [GO:0043931]; plasma membrane organization [GO:0007009]; regulation of metanephric nephron tubule epithelial cell differentiation [GO:0072307] GO:0001658; GO:0001736; GO:0001822; GO:0003007; GO:0005509; GO:0005886; GO:0007009; GO:0007156; GO:0007157; GO:0007219; GO:0008543; GO:0021987; GO:0022008; GO:0035329; GO:0043931; GO:0045177; GO:0048565; GO:0060122; GO:0072006; GO:0072137; GO:0072307; GO:0098609 29220 FUN_043300 275 194 199 261 229 ptg000047l:6739429-6753814 Q8IRC7 7.11e-27 LIM/homeobox protein Awh (Protein arrowhead) Drosophila melanogaster (Fruit fly) compound eye development [GO:0048749]; imaginal disc development [GO:0007444]; neuron differentiation [GO:0030182]; regulation of DNA-templated transcription [GO:0006355]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0007444; GO:0010468; GO:0030182; GO:0046872; GO:0048749 29221 FUN_043301 917 806 449 579 1487 NA NA NA NA NA NA NA 29222 FUN_041230 4 0 7 0 40 NA NA NA NA NA NA NA 29223 FUN_041231 40 63 84 123 69 NA NA NA NA NA NA NA 29224 FUN_013352 472 623 416 484 279 NA NA NA NA NA NA NA 29225 FUN_013355 10 12 0 46 37 NA NA NA NA NA NA NA 29226 FUN_013357 3165 2025 1624 2131 2179 NA NA NA NA NA NA NA 29227 FUN_013358 644 663 545 619 541 NA NA NA NA NA NA NA 29228 FUN_034908 148 278 172 499 375 NA NA NA NA NA NA NA 29229 FUN_034909 100 1719 911 958 947 NA NA NA NA NA NA NA 29230 FUN_034902 3 4 0 5 6 NA NA NA NA NA NA NA 29231 FUN_034900 719 160 45 0 278 NA NA NA NA NA NA NA 29232 FUN_034905 0 0 5 26 44 NA NA NA NA NA NA NA 29233 FUN_035059 0 0 0 0 14 NA NA NA NA NA NA NA 29234 FUN_035058 344 2757 1915 1306 927 NA NA NA NA NA NA NA 29235 FUN_035057 306 166 189 337 227 ptg000025l:3340239-3341572 Q96S44 2.67e-89 EKC/KEOPS complex subunit TP53RK (EC 3.6.-.-) (Atypical serine/threonine protein kinase TP53RK) (Nori-2) (TP53-regulating kinase) (EC 2.7.11.1) (p53-related protein kinase) Homo sapiens (Human) protein phosphorylation [GO:0006468]; regulation of signal transduction by p53 class mediator [GO:1901796]; tRNA processing [GO:0008033]; tRNA threonylcarbamoyladenosine metabolic process [GO:0070525] GO:0000408; GO:0002039; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0008033; GO:0016787; GO:0070525; GO:0106310; GO:1901796 29236 FUN_035056 0 0 0 9 0 NA NA NA NA NA NA NA 29237 FUN_035054 430 270 163 793 353 NA NA NA NA NA NA NA 29238 FUN_035053 10355 8662 3845 9181 4308 ptg000025l:3299206-3299852 Q09930 7.77e-28 GTP-binding protein drn-1 (Di-Ras/Rig/Noey2 Ras-like protein homolog) Caenorhabditis elegans signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 29239 FUN_035052 941 5792 2771 7076 3351 ptg000025l:3293321-3293978 Q96HU8 1.24e-28 GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) Homo sapiens (Human) signal transduction [GO:0007165] GO:0003924; GO:0005525; GO:0005886; GO:0007165; GO:0019003 29240 FUN_035051 951 738 210 393 114 NA NA NA NA NA NA NA 29241 FUN_035050 908 621 378 614 444 NA NA NA NA NA NA NA 29242 FUN_036508 8 6 0 35 28 NA NA NA NA NA NA NA 29243 FUN_036509 524 3978 2354 3797 2447 NA NA NA NA NA NA NA 29244 FUN_036504 2262 1179 1748 2213 1658 ptg000025l:18914662-18956431 Q8I7P9 5.58e-40 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 29245 FUN_036505 347 951 785 1634 524 NA NA NA NA NA NA NA 29246 FUN_036506 736 475 629 1320 550 NA NA NA NA NA NA NA 29247 FUN_036507 321 361 280 848 759 NA NA NA NA NA NA NA 29248 FUN_036500 0 0 6 0 8 NA NA NA NA NA NA NA 29249 FUN_036501 38 42 24 40 38 ptg000025l:18857050-18859650 Q9J569 7.55e-24 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 29250 FUN_036502 154 63 79 107 96 NA NA NA NA NA NA NA 29251 FUN_028136 72 14 112 115 96 NA NA NA NA NA NA NA 29252 FUN_002058 0 12 0 0 0 NA NA NA NA NA NA NA 29253 FUN_003357 21 76 0 11 42 NA NA NA NA NA NA NA 29254 FUN_002053 40 0 26 6 52 NA NA NA NA NA NA NA 29255 FUN_028133 1932 1460 1872 2872 1606 NA NA NA NA NA NA NA 29256 FUN_008488 138 167 210 111 182 ptg000002l:12138956-12141693 Q9NXS3 3.26e-22 Kelch-like protein 28 (BTB/POZ domain-containing protein 5) Homo sapiens (Human) NA NA 29257 FUN_008488 138 167 210 111 182 ptg000002l:12138956-12141693 Q9NXS3 2.22e-21 Kelch-like protein 28 (BTB/POZ domain-containing protein 5) Homo sapiens (Human) NA NA 29258 FUN_028130 6947 4752 5001 5007 3942 NA NA NA NA NA NA NA 29259 FUN_009845 12 77 0 11 3 ptg000004l:12489918-12490662 B4P624 3.86e-53 Facilitated trehalose transporter Tret1 Drosophila yakuba (Fruit fly) trehalose transport [GO:0015771] GO:0005886; GO:0015574; GO:0015771; GO:0051119 29260 FUN_028131 388 160 242 264 221 NA NA NA NA NA NA NA 29261 FUN_040543 215 0 1 2 0 NA NA NA NA NA NA NA 29262 FUN_040544 421 172 33 100 325 ptg000031l:10176737-10187495 Q5DU56 1.56e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29263 FUN_040544 421 172 33 100 325 ptg000031l:10176737-10187495 Q5DU56 2.71e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29264 FUN_040547 7082 3108 3692 7137 6848 ptg000031l:10205085-10253126 Q9JKF1 3.88e-30 Ras GTPase-activating-like protein IQGAP1 Mus musculus (Mouse) cell migration [GO:0016477]; cellular response to calcium ion [GO:0071277]; cellular response to epidermal growth factor stimulus [GO:0071364]; cellular response to fibroblast growth factor stimulus [GO:0044344]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; epidermal growth factor receptor signaling pathway [GO:0007173]; fibroblast growth factor receptor signaling pathway [GO:0008543]; fibroblast migration [GO:0010761]; negative regulation of dephosphorylation [GO:0035305]; neuron projection extension [GO:1990138]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; podocyte development [GO:0072015]; positive regulation of dendrite development [GO:1900006]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of peptidyl-tyrosine autophosphorylation [GO:1900086]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein localization [GO:1903829]; positive regulation of vascular associated smooth muscle cell migration [GO:1904754]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cytokine production [GO:0001817]; regulation of GTPase activity [GO:0043087]; regulation of mitotic cell cycle [GO:0007346]; response to angiotensin [GO:1990776] GO:0001726; GO:0001817; GO:0005078; GO:0005096; GO:0005509; GO:0005516; GO:0005547; GO:0005634; GO:0005737; GO:0005874; GO:0005886; GO:0005911; GO:0005925; GO:0007173; GO:0007346; GO:0008543; GO:0010761; GO:0015629; GO:0015630; GO:0016323; GO:0016324; GO:0016328; GO:0016477; GO:0019901; GO:0019903; GO:0019904; GO:0030424; GO:0030426; GO:0030496; GO:0030864; GO:0031234; GO:0031252; GO:0031267; GO:0032956; GO:0032991; GO:0035305; GO:0036057; GO:0036120; GO:0036464; GO:0043005; GO:0043087; GO:0043406; GO:0043410; GO:0043539; GO:0044344; GO:0044548; GO:0044877; GO:0045121; GO:0045860; GO:0048008; GO:0051015; GO:0051019; GO:0051894; GO:0060090; GO:0071277; GO:0071364; GO:0072015; GO:1900006; GO:1900086; GO:1903829; GO:1904754; GO:1990138; GO:1990776; GO:1990904 29265 FUN_040549 322 228 282 427 598 ptg000031l:10288590-10291886 Q2TBV6 1.32e-21 Coiled-coil domain-containing protein 124 Bos taurus (Bovine) cell cycle [GO:0007049]; cell division [GO:0051301]; transcription by RNA polymerase II [GO:0006366] GO:0003713; GO:0005634; GO:0005815; GO:0005829; GO:0005886; GO:0006366; GO:0007049; GO:0030496; GO:0051301 29266 FUN_040548 987 745 531 1064 874 NA NA NA NA NA NA NA 29267 FUN_003908 0 0 0 0 18 NA NA NA NA NA NA NA 29268 FUN_003909 0 0 0 0 6 NA NA NA NA NA NA NA 29269 FUN_003900 1570 1121 1048 1645 1593 NA NA NA NA NA NA NA 29270 FUN_003901 1106 1243 928 1059 900 NA NA NA NA NA NA NA 29271 FUN_003902 25 3 0 0 35 ntLink_8:16707571-16713842 O70165 8.22e-42 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 29272 FUN_003903 54 46 89 41 66 ntLink_8:16720165-16723513 P19477 1.1e-43 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 29273 FUN_003904 108 196 102 249 203 ntLink_8:16730389-16781299 P19477 1.79e-40 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 29274 FUN_003904 108 196 102 249 203 ntLink_8:16730389-16781299 P19477 8.16e-40 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 29275 FUN_003904 108 196 102 249 203 ntLink_8:16730389-16781299 P19477 1.74e-39 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 29276 FUN_003904 108 196 102 249 203 ntLink_8:16730389-16781299 P19477 2.6e-38 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 29277 FUN_003905 0 18 0 0 0 NA NA NA NA NA NA NA 29278 FUN_003907 88 65 73 42 56 NA NA NA NA NA NA NA 29279 FUN_010190 15 30 7 8 39 NA NA NA NA NA NA NA 29280 FUN_012905 99 36 323 87 117 NA NA NA NA NA NA NA 29281 FUN_012902 21 0 18 4 24 NA NA NA NA NA NA NA 29282 FUN_012903 62 0 25 60 128 NA NA NA NA NA NA NA 29283 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 1.51e-78 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29284 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 4.22e-31 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29285 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 1.04e-30 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29286 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 6.43e-28 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29287 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 1.47e-24 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29288 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 3.11e-21 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29289 FUN_024566 15971 5626 7239 15119 14144 ptg000018l:8443198-8458101 P81436 6.61e-21 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) Oryctolagus cuniculus (Rabbit) apoptotic process [GO:0006915]; chromatin organization [GO:0006325]; circadian regulation of gene expression [GO:0032922]; negative regulation of protein ubiquitination [GO:0031397]; phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of histone H3-K27 methylation [GO:0061087]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein O-linked glycosylation [GO:0006493]; protein processing [GO:0016485]; regulation of gluconeogenesis [GO:0006111]; regulation of glycolytic process [GO:0006110] GO:0000123; GO:0005547; GO:0005634; GO:0005886; GO:0006110; GO:0006111; GO:0006325; GO:0006493; GO:0006915; GO:0016485; GO:0017122; GO:0031397; GO:0031966; GO:0032922; GO:0042995; GO:0045944; GO:0048015; GO:0061087; GO:0097363 29290 FUN_032085 80 64 78 56 71 NA NA NA NA NA NA NA 29291 FUN_032087 307 189 258 232 217 NA NA NA NA NA NA NA 29292 FUN_032086 946 316 538 651 506 NA NA NA NA NA NA NA 29293 FUN_032081 1538 2305 4978 17267 8091 NA NA NA NA NA NA NA 29294 FUN_032080 370 512 253 615 424 ptg000023l:28677179-28680286 Q1PSW8 4.02e-21 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 29295 FUN_032083 167 262 100 246 175 NA NA NA NA NA NA NA 29296 FUN_032082 895 1130 1378 3820 2824 ptg000023l:28692426-28696113 Q9D2G9 2.98e-68 HHIP-like protein 2 Mus musculus (Mouse) NA GO:0005576 29297 FUN_032082 895 1130 1378 3820 2824 ptg000023l:28692426-28696113 Q9D2G9 2.01e-31 HHIP-like protein 2 Mus musculus (Mouse) NA GO:0005576 29298 FUN_032089 39 271 56 0 12 NA NA NA NA NA NA NA 29299 FUN_032088 1509 1636 1637 3716 2307 NA NA NA NA NA NA NA 29300 FUN_043896 4 4 19 1 136 NA NA NA NA NA NA NA 29301 FUN_043897 0 2 10 60 0 NA NA NA NA NA NA NA 29302 FUN_043894 6 11 10 19 41 NA NA NA NA NA NA NA 29303 FUN_043895 18 83 42 74 189 NA NA NA NA NA NA NA 29304 FUN_043892 20 113 19 63 175 NA NA NA NA NA NA NA 29305 FUN_043893 9 2 18 9 138 NA NA NA NA NA NA NA 29306 FUN_043890 4 31 14 10 105 NA NA NA NA NA NA NA 29307 FUN_043891 24 74 49 71 212 NA NA NA NA NA NA NA 29308 FUN_032337 18 9 17 15 56 NA NA NA NA NA NA NA 29309 FUN_032336 0 0 21 0 7 NA NA NA NA NA NA NA 29310 FUN_032335 0 0 38 50 4 NA NA NA NA NA NA NA 29311 FUN_032334 0 0 12 7 37 NA NA NA NA NA NA NA 29312 FUN_032332 0 0 0 15 12 NA NA NA NA NA NA NA 29313 FUN_032331 0 6 0 0 0 NA NA NA NA NA NA NA 29314 FUN_043899 0 2 16 83 0 NA NA NA NA NA NA NA 29315 FUN_011249 0 0 11 7 48 NA NA NA NA NA NA NA 29316 FUN_000959 1045 1011 744 1033 629 NA NA NA NA NA NA NA 29317 FUN_011244 0 0 0 154 16 NA NA NA NA NA NA NA 29318 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 1.44e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29319 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 2.08e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29320 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 2.08e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29321 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 5.03e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29322 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 6.28e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29323 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 1.7e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29324 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 1.33e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29325 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 1.66e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29326 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 5.83e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29327 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 2.54e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29328 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 2.67e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29329 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 1.26e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29330 FUN_000343 119 43 83 270 31 ntLink_6:1762960-1764939 Q96AY4 1.43e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29331 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 9.12e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29332 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 7.5e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29333 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 5.55e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29334 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 2.46e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29335 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 3.43e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29336 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 1.67e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29337 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 1.59e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29338 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 2.72e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29339 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 1.05e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29340 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 5.46e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29341 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 1.31e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29342 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 2.52e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29343 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 2.16e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29344 FUN_000342 175 33 131 457 35 ntLink_6:1761499-1762883 Q96AY4 1.72e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29345 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 2.69e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29346 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 5.22e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29347 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 6.16e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29348 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 2.72e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29349 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 2.77e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29350 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 7.29e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29351 FUN_000341 993 1345 485 1509 1578 ntLink_6:1743690-1754153 Q96AY4 1.69e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29352 FUN_000340 344 215 130 163 312 NA NA NA NA NA NA NA 29353 FUN_000347 829 167 212 303 164 NA NA NA NA NA NA NA 29354 FUN_000346 264 198 71 80 61 NA NA NA NA NA NA NA 29355 FUN_041799 647 685 183 882 446 NA NA NA NA NA NA NA 29356 FUN_000344 119 9 34 164 114 NA NA NA NA NA NA NA 29357 FUN_041797 128 64 146 182 95 NA NA NA NA NA NA NA 29358 FUN_000349 27 0 12 2 95 NA NA NA NA NA NA NA 29359 FUN_000348 671 272 117 354 431 NA NA NA NA NA NA NA 29360 FUN_041790 3004 2552 841 3395 2896 NA NA NA NA NA NA NA 29361 FUN_041941 1677 1079 807 1663 1463 NA NA NA NA NA NA NA 29362 FUN_008646 1188 632 738 1187 657 ptg000002l:13995856-14004789 Q8BJA2 5.62e-28 Solute carrier family 41 member 1 Mus musculus (Mouse) cellular magnesium ion homeostasis [GO:0010961]; cellular response to magnesium ion [GO:0071286]; magnesium ion transmembrane transport [GO:1903830]; magnesium ion transport [GO:0015693]; metal ion transport [GO:0030001] GO:0005886; GO:0010961; GO:0015095; GO:0015693; GO:0016323; GO:0022857; GO:0022890; GO:0030001; GO:0032991; GO:0061768; GO:0071286; GO:1903830 29363 FUN_008644 828 538 353 606 476 NA NA NA NA NA NA NA 29364 FUN_008645 59 13 23 37 190 NA NA NA NA NA NA NA 29365 FUN_008642 14387 9712 6520 13055 10766 ptg000002l:13969866-13976932 O08663 3.56e-30 Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2) (Peptidase M) Mus musculus (Mouse) N-terminal protein amino acid modification [GO:0031365]; peptidyl-methionine modification [GO:0018206]; protein initiator methionine removal involved in protein maturation [GO:0035551]; protein processing [GO:0016485] GO:0004177; GO:0005737; GO:0005829; GO:0005886; GO:0008235; GO:0016485; GO:0018206; GO:0031365; GO:0035551; GO:0046872; GO:0070006 29366 FUN_008643 0 28 0 0 97 NA NA NA NA NA NA NA 29367 FUN_008640 334 394 426 447 327 NA NA NA NA NA NA NA 29368 FUN_008641 939 1017 644 1002 849 ptg000002l:13951259-13962431 Q6XPR3 2.14e-26 Repetin Homo sapiens (Human) NA GO:0001533; GO:0005509; GO:0005576; GO:0005829; GO:0046914 29369 FUN_008648 919 253 334 565 387 NA NA NA NA NA NA NA 29370 FUN_008649 1930 1398 527 1472 828 NA NA NA NA NA NA NA 29371 FUN_029016 37 22 4 7 75 NA NA NA NA NA NA NA 29372 FUN_029017 4792 2446 2682 4572 2698 NA NA NA NA NA NA NA 29373 FUN_014995 9618 4282 4541 6899 5818 NA NA NA NA NA NA NA 29374 FUN_029015 0 12 4 27 7 NA NA NA NA NA NA NA 29375 FUN_029012 223 115 73 140 288 ptg000022l:7202548-7210454 B8VIW9 2.75e-22 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29376 FUN_029013 2438 1454 1519 3476 1643 ptg000022l:7211003-7221741 B8VIW9 2.19e-30 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29377 FUN_029013 2438 1454 1519 3476 1643 ptg000022l:7211003-7221741 B8VIW9 1.85e-26 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29378 FUN_029013 2438 1454 1519 3476 1643 ptg000022l:7211003-7221741 B8VIW9 1.26e-25 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29379 FUN_029013 2438 1454 1519 3476 1643 ptg000022l:7211003-7221741 B8VIW9 1.29e-22 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29380 FUN_029013 2438 1454 1519 3476 1643 ptg000022l:7211003-7221741 B8VIW9 2.01e-21 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29381 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 9.16e-60 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29382 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 8.5e-58 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29383 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 1.94e-55 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29384 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 3.53e-55 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29385 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 1.21e-52 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29386 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 3.3e-51 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29387 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 2.02e-50 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29388 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 8.97e-50 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29389 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 2.23e-49 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29390 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 2.2e-46 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29391 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 8.37e-46 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29392 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 3.77e-41 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29393 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 1.73e-36 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29394 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 4.03e-36 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29395 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 2.61e-32 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29396 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 3.23e-32 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29397 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 2.69e-30 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29398 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 1.1e-29 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29399 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 3.68e-29 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29400 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 4.28e-27 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29401 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 8.99e-27 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29402 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 7.08e-25 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29403 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 1.77e-24 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29404 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 2.79e-24 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29405 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 5.16e-23 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29406 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 5.14e-22 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29407 FUN_029010 1572 1283 770 1552 905 ptg000022l:7094698-7190681 B8VIW9 3.04e-21 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29408 FUN_014990 7 7 11 13 60 NA NA NA NA NA NA NA 29409 FUN_014998 492 1198 734 829 959 NA NA NA NA NA NA NA 29410 FUN_028683 1 0 9 0 0 NA NA NA NA NA NA NA 29411 FUN_033069 0 0 0 0 6 NA NA NA NA NA NA NA 29412 FUN_033066 53 12 46 18 90 NA NA NA NA NA NA NA 29413 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.02e-54 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29414 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.29e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29415 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 2.85e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29416 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 3.41e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29417 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 3.59e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29418 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 3.59e-52 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29419 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.69e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29420 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.79e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29421 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.97e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29422 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 3.1e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29423 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 3.49e-51 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29424 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.03e-50 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29425 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 1.96e-26 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29426 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 4.91e-23 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29427 FUN_033067 0 190 4 50 5 ptg000023l:39581603-39585448 Q9UGM3 7.17e-21 Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein) Homo sapiens (Human) antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of bacterial lipoprotein [GO:0042494]; epithelial cell differentiation [GO:0030855]; induction of bacterial agglutination [GO:0043152]; innate immune response [GO:0045087]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898] GO:0001530; GO:0003677; GO:0005044; GO:0005576; GO:0005615; GO:0005737; GO:0006898; GO:0006952; GO:0015031; GO:0019898; GO:0030670; GO:0030855; GO:0031012; GO:0035375; GO:0038187; GO:0042494; GO:0042589; GO:0043152; GO:0045087; GO:0048306; GO:0050829; GO:0050830; GO:0050840; GO:0051607; GO:0061844; GO:0070062; GO:0070891; GO:1904399 29428 FUN_033060 0 0 0 0 9 NA NA NA NA NA NA NA 29429 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 1.6e-38 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29430 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 9.87e-31 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29431 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 9.24e-28 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29432 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 6.72e-26 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29433 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 1.65e-25 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29434 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 2.26e-23 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29435 FUN_033061 131 9 81 103 173 ptg000023l:39527438-39532995 F7J220 2.91e-21 Scavenger receptor cysteine-rich domain superfamily protein (ApSRCR1) Patiria pectinifera (Starfish) (Asterina pectinifera) innate immune response [GO:0045087]; phagocytosis [GO:0006909] GO:0005044; GO:0006909; GO:0030659; GO:0045087 29436 FUN_033062 29 24 0 3 75 NA NA NA NA NA NA NA 29437 FUN_041244 0 11 12 1 8 NA NA NA NA NA NA NA 29438 FUN_041247 110 26 61 83 66 NA NA NA NA NA NA NA 29439 FUN_013326 2672 1932 1090 2835 2146 NA NA NA NA NA NA NA 29440 FUN_013329 846 391 566 1345 975 NA NA NA NA NA NA NA 29441 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 4.7e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29442 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 8.9e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29443 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 1e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29444 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 4.11e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29445 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 3.38e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29446 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 1.15e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29447 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 4.15e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29448 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 4.9e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29449 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 1.59e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29450 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 2.04e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29451 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 1.02e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29452 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 1.45e-60 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29453 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 1.24e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29454 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 2.51e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29455 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 3.41e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29456 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 2.39e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29457 FUN_028689 30 37 0 78 0 ptg000022l:2672777-2720512 Q96AY4 7.2e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29458 FUN_042859 1 12 0 0 51 NA NA NA NA NA NA NA 29459 FUN_042851 1546 1218 529 841 904 ptg000047l:904556-923704 P62289 4.12e-95 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 29460 FUN_042851 1546 1218 529 841 904 ptg000047l:904556-923704 P62289 1.58e-88 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 29461 FUN_042851 1546 1218 529 841 904 ptg000047l:904556-923704 P62289 5.95e-71 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 29462 FUN_042851 1546 1218 529 841 904 ptg000047l:904556-923704 P62289 2.05e-68 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 29463 FUN_016730 0 22 0 0 0 NA NA NA NA NA NA NA 29464 FUN_042853 409 228 134 429 327 NA NA NA NA NA NA NA 29465 FUN_042852 272 428 326 477 697 NA NA NA NA NA NA NA 29466 FUN_016735 206 77 68 201 49 NA NA NA NA NA NA NA 29467 FUN_016734 10 4 0 4 0 NA NA NA NA NA NA NA 29468 FUN_016737 374 177 218 492 214 NA NA NA NA NA NA NA 29469 FUN_042856 529 290 484 574 397 NA NA NA NA NA NA NA 29470 FUN_024444 412 324 227 326 238 ptg000018l:6421033-6424325 Q08BL7 1.62e-53 Glycerate kinase (EC 2.7.1.31) Danio rerio (Zebrafish) (Brachydanio rerio) protein phosphorylation [GO:0006468] GO:0005524; GO:0005737; GO:0006468; GO:0008887 29471 FUN_024444 412 324 227 326 238 ptg000018l:6421033-6424325 Q08BL7 2.94e-22 Glycerate kinase (EC 2.7.1.31) Danio rerio (Zebrafish) (Brachydanio rerio) protein phosphorylation [GO:0006468] GO:0005524; GO:0005737; GO:0006468; GO:0008887 29472 FUN_012296 4383 1776 1705 2726 2888 NA NA NA NA NA NA NA 29473 FUN_012297 227 170 150 255 352 NA NA NA NA NA NA NA 29474 FUN_012295 2309 858 892 886 762 NA NA NA NA NA NA NA 29475 FUN_012292 129 285 25 361 147 NA NA NA NA NA NA NA 29476 FUN_012293 3389 2621 2217 6449 6339 NA NA NA NA NA NA NA 29477 FUN_012290 0 0 11 0 25 NA NA NA NA NA NA NA 29478 FUN_012298 1440 742 628 1088 627 NA NA NA NA NA NA NA 29479 FUN_012299 65 34 15 33 15 NA NA NA NA NA NA NA 29480 FUN_000950 10 22 31 39 3 NA NA NA NA NA NA NA 29481 FUN_036668 0 0 5 0 10 NA NA NA NA NA NA NA 29482 FUN_010676 1344 1058 792 1375 1024 ptg000007l:1492526-1493102 P42325 3.58e-128 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 29483 FUN_010677 8183 6997 3080 7341 4524 ptg000007l:1495627-1496200 P42325 4.13e-119 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 29484 FUN_010674 4429 2216 2798 4974 3726 NA NA NA NA NA NA NA 29485 FUN_010675 2507 1488 885 1693 1646 NA NA NA NA NA NA NA 29486 FUN_010672 333 218 293 363 429 ptg000007l:1396828-1419679 Q96DM1 2.65e-44 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 29487 FUN_010673 1191 729 795 1248 1379 NA NA NA NA NA NA NA 29488 FUN_010670 87 47 61 65 23 NA NA NA NA NA NA NA 29489 FUN_010671 17 37 4 0 18 NA NA NA NA NA NA NA 29490 FUN_010678 1278 385 59 934 25 ptg000007l:1498531-1501280 P42325 5.27e-103 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 29491 FUN_010679 1898 1256 421 1067 1109 ptg000007l:1503971-1512636 Q7ZWF0 8.49e-43 mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) Danio rerio (Zebrafish) (Brachydanio rerio) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic spindle organization [GO:0060236]; RNA export from nucleus [GO:0006405]; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [GO:0000972] GO:0000972; GO:0003723; GO:0005643; GO:0005737; GO:0006405; GO:0007049; GO:0043130; GO:0051301; GO:0060236; GO:0097431 29492 FUN_012128 127 71 0 232 26 NA NA NA NA NA NA NA 29493 FUN_012129 35 0 4 0 15 NA NA NA NA NA NA NA 29494 FUN_012120 6153 2403 2146 4355 4184 ptg000008l:5311205-5332372 Q9ERH8 1.36e-24 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (mCNT3) Mus musculus (Mouse) nucleoside transmembrane transport [GO:1901642]; purine nucleoside transmembrane transport [GO:0015860]; pyrimidine nucleoside transport [GO:0015864]; pyrimidine-containing compound transmembrane transport [GO:0072531]; retina homeostasis [GO:0001895]; uridine transport [GO:0015862] GO:0001895; GO:0005337; GO:0005415; GO:0005886; GO:0015213; GO:0015293; GO:0015389; GO:0015390; GO:0015860; GO:0015862; GO:0015864; GO:0031526; GO:0072531; GO:1901642 29495 FUN_012121 157 82 0 163 133 NA NA NA NA NA NA NA 29496 FUN_012122 4791 975 950 4156 2476 NA NA NA NA NA NA NA 29497 FUN_012125 524 17 292 1271 867 NA NA NA NA NA NA NA 29498 FUN_012126 579 45 136 108 172 NA NA NA NA NA NA NA 29499 FUN_020822 6 8 12 0 2 NA NA NA NA NA NA NA 29500 FUN_020823 0 0 0 0 12 NA NA NA NA NA NA NA 29501 FUN_020824 33 0 32 10 156 NA NA NA NA NA NA NA 29502 FUN_020829 9 10 1 0 5 NA NA NA NA NA NA NA 29503 FUN_038810 47 16 48 45 82 NA NA NA NA NA NA NA 29504 FUN_038811 1559 949 697 1533 1424 ptg000027l:11635491-11652138 A8Y5H7 1.41e-22 SEC14-like protein 1 Mus musculus (Mouse) choline transport [GO:0015871]; innate immune response [GO:0045087]; negative regulation of RIG-I signaling pathway [GO:0039536] GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0015871; GO:0039536; GO:0039552; GO:0045087 29505 FUN_038813 45 22 4 5 12 ptg000027l:11659478-11663461 Q86WA9 1.97e-42 Sodium-independent sulfate anion transporter (Solute carrier family 26 member 11) Homo sapiens (Human) ion transport [GO:0006811]; sulfate transport [GO:0008272] GO:0005654; GO:0005765; GO:0005783; GO:0005794; GO:0005886; GO:0006811; GO:0008271; GO:0008272; GO:0008509; GO:0015116; GO:0016020; GO:0043231; GO:0070062 29506 FUN_038814 2588 1069 1041 1811 1233 ptg000027l:11663622-11674154 G3C7W6 6.33e-64 NA NA NA NA 29507 FUN_038814 2588 1069 1041 1811 1233 ptg000027l:11663622-11674154 G3C7W6 1.64e-52 NA NA NA NA 29508 FUN_038814 2588 1069 1041 1811 1233 ptg000027l:11663622-11674154 G3C7W6 1.28e-30 NA NA NA NA 29509 FUN_038815 8585 10569 5354 7440 5829 ptg000027l:11676464-11681007 Q5XHA2 5.29e-42 ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein retention in ER lumen [GO:0006621]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005046; GO:0005789; GO:0006621; GO:0006890; GO:0015031; GO:0030663; GO:0033116 29510 FUN_038815 8585 10569 5354 7440 5829 ptg000027l:11676464-11681007 Q5XHA2 4.2e-31 ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein retention in ER lumen [GO:0006621]; protein transport [GO:0015031]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000139; GO:0005046; GO:0005789; GO:0006621; GO:0006890; GO:0015031; GO:0030663; GO:0033116 29511 FUN_038816 577 139 158 388 353 NA NA NA NA NA NA NA 29512 FUN_038817 507 368 328 569 361 NA NA NA NA NA NA NA 29513 FUN_038819 6317 9434 3630 7375 6116 NA NA NA NA NA NA NA 29514 FUN_011284 1463 1358 1294 1498 2279 NA NA NA NA NA NA NA 29515 FUN_041759 1200 1101 535 774 657 ptg000035l:7201250-7207879 Q0IHV9 2.64e-33 Probable ATP-dependent RNA helicase ddx6 (EC 3.6.4.13) (DEAD box protein 6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962]; response to heat [GO:0009408]; stress granule assembly [GO:0034063] GO:0000932; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0009408; GO:0016887; GO:0017148; GO:0033962; GO:0034063; GO:0035278; GO:1990904 29516 FUN_041759 1200 1101 535 774 657 ptg000035l:7201250-7207879 Q0IHV9 1.61e-31 Probable ATP-dependent RNA helicase ddx6 (EC 3.6.4.13) (DEAD box protein 6) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; P-body assembly [GO:0033962]; response to heat [GO:0009408]; stress granule assembly [GO:0034063] GO:0000932; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0009408; GO:0016887; GO:0017148; GO:0033962; GO:0034063; GO:0035278; GO:1990904 29517 FUN_011287 1171 1410 709 667 1101 ptg000007l:8623386-8631686 Q8N0X4 1.58e-21 Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9) Homo sapiens (Human) positive regulation of cobalamin metabolic process [GO:0106121]; protein homotrimerization [GO:0070207]; regulation of cobalamin metabolic process [GO:0106064] GO:0000287; GO:0004474; GO:0005739; GO:0016787; GO:0047777; GO:0070207; GO:0106064; GO:0106121 29518 FUN_011287 1171 1410 709 667 1101 ptg000007l:8623386-8631686 Q8N0X4 1.58e-21 Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9) Homo sapiens (Human) positive regulation of cobalamin metabolic process [GO:0106121]; protein homotrimerization [GO:0070207]; regulation of cobalamin metabolic process [GO:0106064] GO:0000287; GO:0004474; GO:0005739; GO:0016787; GO:0047777; GO:0070207; GO:0106064; GO:0106121 29519 FUN_016678 74 0 71 58 13 ptg000011l:6215306-6221947 Q06496 5.47e-55 Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1) Rattus norvegicus (Rat) arsenate ion transmembrane transport [GO:1901684]; bone remodeling [GO:0046849]; calcium ion homeostasis [GO:0055074]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to metal ion [GO:0071248]; cellular response to parathyroid hormone stimulus [GO:0071374]; cellular response to phosphate starvation [GO:0016036]; cellular response to staurosporine [GO:0072734]; dentinogenesis [GO:0097187]; gene expression [GO:0010467]; gentamycin metabolic process [GO:1901128]; glycoprotein metabolic process [GO:0009100]; indole metabolic process [GO:0042431]; inorganic diphosphate transport [GO:0030505]; kidney development [GO:0001822]; ossification [GO:0001503]; phosphate ion homeostasis [GO:0055062]; phosphate ion transmembrane transport [GO:0035435]; phosphate ion transport [GO:0006817]; positive regulation of membrane potential [GO:0045838]; positive regulation of phosphate transmembrane transport [GO:2000187]; positive regulation of sodium-dependent phosphate transport [GO:2000120]; response to cadmium ion [GO:0046686]; response to estradiol [GO:0032355]; response to growth hormone [GO:0060416]; response to lead ion [GO:0010288]; response to magnesium ion [GO:0032026]; response to mercury ion [GO:0046689]; response to nutrient [GO:0007584]; response to parathyroid hormone [GO:0071107]; response to peptide [GO:1901652]; response to peptide hormone [GO:0043434]; response to potassium ion [GO:0035864]; response to sodium phosphate [GO:1904383]; response to thyroid hormone [GO:0097066]; response to vitamin A [GO:0033189]; response to xenobiotic stimulus [GO:0009410]; sodium ion import across plasma membrane [GO:0098719]; sodium-dependent phosphate transport [GO:0044341]; tricarboxylic acid metabolic process [GO:0072350] GO:0001503; GO:0001822; GO:0005436; GO:0005768; GO:0005829; GO:0005886; GO:0005903; GO:0006817; GO:0007584; GO:0009100; GO:0009410; GO:0009986; GO:0010288; GO:0010467; GO:0016036; GO:0016323; GO:0016324; GO:0016607; GO:0030165; GO:0030505; GO:0030643; GO:0031526; GO:0031982; GO:0032026; GO:0032355; GO:0033189; GO:0035435; GO:0035864; GO:0042431; GO:0042802; GO:0043434; GO:0044341; GO:0044877; GO:0045121; GO:0045838; GO:0046686; GO:0046689; GO:0046849; GO:0048471; GO:0055062; GO:0055074; GO:0060416; GO:0071107; GO:0071248; GO:0071374; GO:0072350; GO:0072686; GO:0072734; GO:0097066; GO:0097187; GO:0098719; GO:1901128; GO:1901652; GO:1901684; GO:1904383; GO:2000120; GO:2000187 29520 FUN_011282 130 35 67 188 118 ptg000007l:8548423-8550270 Q9WTS8 2.82e-31 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Rattus norvegicus (Rat) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation [GO:0006956]; complement activation, lectin pathway [GO:0001867]; defense response to virus [GO:0051607]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of RNA biosynthetic process [GO:1902679]; negative regulation of viral entry into host cell [GO:0046597]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of opsonization [GO:1903028]; proteolysis [GO:0006508]; recognition of apoptotic cell [GO:0043654] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0006508; GO:0006956; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0043654; GO:0046597; GO:0046872; GO:0051607; GO:0062023; GO:0097367; GO:1902679; GO:1903028; GO:1905370 29521 FUN_013659 421 29 73 291 505 NA NA NA NA NA NA NA 29522 FUN_013658 452 65 114 295 497 NA NA NA NA NA NA NA 29523 FUN_014609 2423 2387 1451 2208 1688 NA NA NA NA NA NA NA 29524 FUN_014608 3957 3133 1586 2397 1368 NA NA NA NA NA NA NA 29525 FUN_013651 867 0 829 218 430 NA NA NA NA NA NA NA 29526 FUN_013650 354 313 302 453 193 ptg000008l:25029514-25030408 Q8K4H1 1.24e-67 Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF) Mus musculus (Mouse) 'de novo' NAD biosynthetic process from tryptophan [GO:0034354]; tryptophan catabolic process to kynurenine [GO:0019441] GO:0004061; GO:0005634; GO:0005737; GO:0005829; GO:0019441; GO:0034354 29527 FUN_014605 16354 12112 6539 12323 5046 ptg000009l:1467896-1477063 A6QLR4 4.75e-31 Flotillin-2 Bos taurus (Bovine) cell adhesion [GO:0007155]; protein localization to plasma membrane [GO:0072659]; regulation of myoblast differentiation [GO:0045661] GO:0005768; GO:0005886; GO:0007155; GO:0016600; GO:0030139; GO:0031410; GO:0045661; GO:0072659 29528 FUN_014605 16354 12112 6539 12323 5046 ptg000009l:1467896-1477063 A6QLR4 7.37e-26 Flotillin-2 Bos taurus (Bovine) cell adhesion [GO:0007155]; protein localization to plasma membrane [GO:0072659]; regulation of myoblast differentiation [GO:0045661] GO:0005768; GO:0005886; GO:0007155; GO:0016600; GO:0030139; GO:0031410; GO:0045661; GO:0072659 29529 FUN_014604 174 135 250 127 334 NA NA NA NA NA NA NA 29530 FUN_014603 2320 2211 1075 1712 1003 NA NA NA NA NA NA NA 29531 FUN_013654 2265 677 498 1036 736 NA NA NA NA NA NA NA 29532 FUN_013657 196 37 46 128 252 NA NA NA NA NA NA NA 29533 FUN_013656 95 9 31 79 164 NA NA NA NA NA NA NA 29534 FUN_030151 1 0 0 0 12 NA NA NA NA NA NA NA 29535 FUN_005152 49 6 0 71 41 NA NA NA NA NA NA NA 29536 FUN_000303 28 187 183 118 105 NA NA NA NA NA NA NA 29537 FUN_044204 5 9 18 5 122 NA NA NA NA NA NA NA 29538 FUN_009696 104 226 13 254 102 ptg000004l:10480413-10489506 Q5AXT5 1.65e-31 ATP-dependent DNA helicase PIF1 (EC 3.6.4.12) (DNA repair and recombination helicase PIF1) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; mitochondrial genome maintenance [GO:0000002]; telomere maintenance [GO:0000723] GO:0000002; GO:0000723; GO:0003677; GO:0005524; GO:0005634; GO:0005657; GO:0005739; GO:0006260; GO:0006281; GO:0006310; GO:0016887; GO:0032508; GO:0043139 29539 FUN_009697 8 3 239 248 194 NA NA NA NA NA NA NA 29540 FUN_009694 34 35 0 14 19 NA NA NA NA NA NA NA 29541 FUN_009695 9 0 0 0 8 ptg000004l:10475852-10477283 Q95SX7 4.02e-23 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 29542 FUN_009692 1932 106 271 2576 1909 ptg000004l:10406755-10429570 Q9JLC8 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 29543 FUN_009692 1932 106 271 2576 1909 ptg000004l:10406755-10429570 Q9JLC8 3.87e-50 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 29544 FUN_009692 1932 106 271 2576 1909 ptg000004l:10406755-10429570 Q9JLC8 2.74e-49 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 29545 FUN_009692 1932 106 271 2576 1909 ptg000004l:10406755-10429570 Q9JLC8 6.8e-40 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Mus musculus (Mouse) negative regulation of inclusion body assembly [GO:0090084] GO:0005634; GO:0005737; GO:0005739; GO:0030544; GO:0042802; GO:0050750; GO:0051087; GO:0070628; GO:0090084 29546 FUN_009693 42 227 56 119 156 NA NA NA NA NA NA NA 29547 FUN_030155 1 0 25 1 1 NA NA NA NA NA NA NA 29548 FUN_005156 489 376 244 388 205 NA NA NA NA NA NA NA 29549 FUN_009698 4 0 70 20 10 NA NA NA NA NA NA NA 29550 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 8.26e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29551 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 8.26e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29552 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 3.78e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29553 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 3.78e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29554 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 1.49e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29555 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 1.49e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29556 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 5.49e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29557 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 5.49e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29558 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 2.93e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29559 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 2.93e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29560 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 3.27e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29561 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 3.27e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29562 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 2.4e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29563 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 2.4e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29564 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 1.46e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29565 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 4e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29566 FUN_009699 43 306 82 406 123 ptg000004l:10522790-10528672 Q96AY4 4.5e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29567 FUN_030157 0 3 1 24 1 NA NA NA NA NA NA NA 29568 FUN_044201 29 56 60 68 184 NA NA NA NA NA NA NA 29569 FUN_026286 33 9 0 14 40 ptg000020l:7300089-7303820 P49695 1.18e-30 Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1) Thermomonospora curvata protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 29570 FUN_026286 33 9 0 14 40 ptg000020l:7300089-7303820 P49695 2.57e-21 Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1) Thermomonospora curvata protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 29571 FUN_026286 33 9 0 14 40 ptg000020l:7300089-7303820 P49695 7.88e-21 Probable serine/threonine-protein kinase PkwA (EC 2.7.11.1) Thermomonospora curvata protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 29572 FUN_026287 0 0 56 0 0 NA NA NA NA NA NA NA 29573 FUN_026284 270 139 172 1895 2042 NA NA NA NA NA NA NA 29574 FUN_026282 0 9 0 0 36 NA NA NA NA NA NA NA 29575 FUN_026280 100 149 224 0 24 ptg000020l:7116704-7141967 Q5IS54 1.23e-24 Caspase-3 (CASP-3) (EC 3.4.22.56) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] Pan troglodytes (Chimpanzee) anterior neural tube closure [GO:0061713]; apoptotic process [GO:0006915]; B cell homeostasis [GO:0001782]; cell fate commitment [GO:0045165]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to staurosporine [GO:0072734]; epithelial cell apoptotic process [GO:1904019]; erythrocyte differentiation [GO:0030218]; fibroblast apoptotic process [GO:0044346]; glial cell apoptotic process [GO:0034349]; heart development [GO:0007507]; intrinsic apoptotic signaling pathway in response to osmotic stress [GO:0008627]; keratinocyte differentiation [GO:0030216]; negative regulation of activated T cell proliferation [GO:0046007]; negative regulation of B cell proliferation [GO:0030889]; neuron apoptotic process [GO:0051402]; neuron differentiation [GO:0030182]; neurotrophin TRK receptor signaling pathway [GO:0048011]; positive regulation of amyloid-beta formation [GO:1902004]; positive regulation of apoptotic process [GO:0043065]; protein processing [GO:0016485]; proteolysis [GO:0006508]; regulation of protein stability [GO:0031647]; response to UV [GO:0009411]; response to wounding [GO:0009611]; sensory perception of sound [GO:0007605]; T cell homeostasis [GO:0043029] GO:0001782; GO:0004175; GO:0004190; GO:0004861; GO:0005634; GO:0005737; GO:0005829; GO:0006508; GO:0006915; GO:0006974; GO:0007507; GO:0007605; GO:0008627; GO:0009411; GO:0009611; GO:0016485; GO:0030182; GO:0030216; GO:0030218; GO:0030889; GO:0031647; GO:0034349; GO:0043029; GO:0043065; GO:0044346; GO:0045165; GO:0046007; GO:0048011; GO:0051402; GO:0061713; GO:0072734; GO:0097153; GO:0097199; GO:0097200; GO:1902004; GO:1904019 29576 FUN_026288 127 114 80 162 73 ptg000020l:7318150-7332792 P16157 9.54e-77 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 29577 FUN_026288 127 114 80 162 73 ptg000020l:7318150-7332792 P16157 1.02e-64 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 29578 FUN_026288 127 114 80 162 73 ptg000020l:7318150-7332792 P16157 2.54e-62 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 29579 FUN_026288 127 114 80 162 73 ptg000020l:7318150-7332792 P16157 4.78e-57 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 29580 FUN_026288 127 114 80 162 73 ptg000020l:7318150-7332792 P16157 2.68e-43 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 29581 FUN_009528 1575 1755 741 1845 1325 NA NA NA NA NA NA NA 29582 FUN_009529 1721 1331 967 2840 1292 NA NA NA NA NA NA NA 29583 FUN_025959 0 0 0 0 6 ptg000020l:2432386-2434452 Q86W24 8.03e-26 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 29584 FUN_025959 0 0 0 0 6 ptg000020l:2432386-2434452 Q86W24 5.25e-23 NACHT, LRR and PYD domains-containing protein 14 (Nucleotide-binding oligomerization domain protein 5) Homo sapiens (Human) cell differentiation [GO:0030154]; regulation of inflammatory response [GO:0050727]; spermatogenesis [GO:0007283] GO:0005524; GO:0005737; GO:0007283; GO:0030154; GO:0050727 29585 FUN_009520 0 0 10 18 25 NA NA NA NA NA NA NA 29586 FUN_025952 27 0 0 37 28 ptg000020l:2366268-2373770 Q7RTR2 1.73e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29587 FUN_009522 18 0 40 32 188 ptg000004l:7983768-7993278 Q9VLA2 3.67e-23 Transcription factor glial cells missing 2 (Protein glide-2) Drosophila melanogaster (Fruit fly) dendrite morphogenesis [GO:0048813]; embryonic crystal cell differentiation [GO:0035165]; glial cell development [GO:0021782]; glial cell differentiation [GO:0010001]; gliogenesis [GO:0042063]; hemocyte differentiation [GO:0042386]; negative regulation of crystal cell differentiation [GO:0042690]; neuron differentiation [GO:0030182]; plasmatocyte differentiation [GO:0042387]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0001228; GO:0003700; GO:0005634; GO:0006357; GO:0010001; GO:0021782; GO:0030182; GO:0035165; GO:0042063; GO:0042386; GO:0042387; GO:0042690; GO:0048813 29588 FUN_025950 12065 11365 5609 6719 5636 NA NA NA NA NA NA NA 29589 FUN_009524 0 0 0 0 27 NA NA NA NA NA NA NA 29590 FUN_025955 131 40 61 62 121 ptg000020l:2397241-2406544 C3VPR6 2.59e-25 Protein NLRC5 Mus musculus (Mouse) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 29591 FUN_025954 9 0 11 12 68 ptg000020l:2384182-2387826 Q7RTR2 5.56e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29592 FUN_044208 42 96 101 96 285 NA NA NA NA NA NA NA 29593 FUN_027802 117 81 0 86 190 NA NA NA NA NA NA NA 29594 FUN_044209 10 4 26 2 159 NA NA NA NA NA NA NA 29595 FUN_026758 27 3 7 4 72 NA NA NA NA NA NA NA 29596 FUN_023509 169 170 93 136 32 ptg000017l:8394772-8396345 Q9C056 6.7e-37 Homeobox protein Nkx-6.2 (Homeobox protein NK-6 homolog B) Homo sapiens (Human) cell differentiation [GO:0030154]; central nervous system myelination [GO:0022010]; negative regulation of cell fate commitment [GO:0010454]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of oligodendrocyte differentiation [GO:0048715]; neuromuscular process controlling balance [GO:0050885]; neuron fate commitment [GO:0048663]; pancreatic A cell differentiation [GO:0003310]; positive regulation of cell fate commitment [GO:0010455]; positive regulation of oligodendrocyte differentiation [GO:0048714]; regulation of DNA-templated transcription [GO:0006355]; regulation of myelination [GO:0031641]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0001227; GO:0003310; GO:0003677; GO:0003700; GO:0005634; GO:0006355; GO:0006357; GO:0010454; GO:0010455; GO:0022010; GO:0030154; GO:0031641; GO:0045892; GO:0048663; GO:0048714; GO:0048715; GO:0050885; GO:1990837 29597 FUN_031687 609 512 126 657 392 ptg000023l:24408319-24413151 A1L1W9 3.49e-21 Monocarboxylate transporter 10 (MCT 10) (Solute carrier family 16 member 10) Danio rerio (Zebrafish) (Brachydanio rerio) aromatic amino acid transport [GO:0015801]; thyroid hormone transport [GO:0070327] GO:0005302; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0070327 29598 FUN_026751 0 11 0 0 0 NA NA NA NA NA NA NA 29599 FUN_023500 1627 1624 1167 1260 840 NA NA NA NA NA NA NA 29600 FUN_023501 359 347 216 368 336 NA NA NA NA NA NA NA 29601 FUN_023506 10 0 0 0 0 NA NA NA NA NA NA NA 29602 FUN_023507 1837 1260 993 1779 1712 NA NA NA NA NA NA NA 29603 FUN_023505 4 36 19 0 66 NA NA NA NA NA NA NA 29604 FUN_001963 66 13 23 25 25 NA NA NA NA NA NA NA 29605 FUN_031682 61 29 30 119 94 NA NA NA NA NA NA NA 29606 FUN_031683 457 239 120 227 93 NA NA NA NA NA NA NA 29607 FUN_025488 9 1 9 27 41 ptg000019l:3399869-3405370 P14381 6.43e-106 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 29608 FUN_025485 0 72 32 116 170 NA NA NA NA NA NA NA 29609 FUN_025487 3 35 98 36 63 NA NA NA NA NA NA NA 29610 FUN_025486 23 198 20 117 270 NA NA NA NA NA NA NA 29611 FUN_022453 47 0 28 0 61 NA NA NA NA NA NA NA 29612 FUN_025483 28 0 24 0 116 ptg000019l:3317542-3329541 Q61555 1.43e-23 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 29613 FUN_025483 28 0 24 0 116 ptg000019l:3317542-3329541 Q61555 1.9e-21 Fibrillin-2 [Cleaved into: Placensin] Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; limb morphogenesis [GO:0035108]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030326; GO:0030501; GO:0031012; GO:0035108; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 29614 FUN_022450 190 337 151 209 204 NA NA NA NA NA NA NA 29615 FUN_026939 0 10 0 0 0 NA NA NA NA NA NA NA 29616 FUN_009051 19 16 22 48 44 NA NA NA NA NA NA NA 29617 FUN_009052 174 99 20 82 82 NA NA NA NA NA NA NA 29618 FUN_002001 0 0 0 0 82 NA NA NA NA NA NA NA 29619 FUN_009054 265 230 140 259 226 ptg000004l:2180757-2184803 Q9WVK8 6.28e-30 Cholesterol 24-hydroxylase (CH24H) (EC 1.14.14.25) (Cholesterol 24-monooxygenase) (Cholesterol 24S-hydroxylase) (Cytochrome P450 46A1) Mus musculus (Mouse) cholesterol catabolic process [GO:0006707]; progesterone metabolic process [GO:0042448]; protein localization to membrane raft [GO:1903044]; regulation of long-term synaptic potentiation [GO:1900271]; xenobiotic metabolic process [GO:0006805] GO:0005506; GO:0005789; GO:0006707; GO:0006805; GO:0008395; GO:0020037; GO:0030425; GO:0033781; GO:0042448; GO:0062184; GO:0098793; GO:0098794; GO:1900271; GO:1903044 29620 FUN_018608 1 2 4 61 2 NA NA NA NA NA NA NA 29621 FUN_009056 485 387 338 272 333 NA NA NA NA NA NA NA 29622 FUN_009057 0 47 31 0 0 NA NA NA NA NA NA NA 29623 FUN_018607 0 0 14 0 2 NA NA NA NA NA NA NA 29624 FUN_018605 0 148 0 7 140 ptg000012l:11057226-11074533 P0CT39 2.08e-77 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 29625 FUN_018605 0 148 0 7 140 ptg000012l:11057226-11074533 P0CT39 2.08e-77 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 29626 FUN_018604 582 412 153 321 384 NA NA NA NA NA NA NA 29627 FUN_025228 408 180 327 57 733 ptg000019l:225497-230625 Q96AY4 4.21e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29628 FUN_025228 408 180 327 57 733 ptg000019l:225497-230625 Q96AY4 9.86e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29629 FUN_025228 408 180 327 57 733 ptg000019l:225497-230625 Q96AY4 2.69e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29630 FUN_025228 408 180 327 57 733 ptg000019l:225497-230625 Q96AY4 3.76e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29631 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 2.76e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29632 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 1.11e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29633 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 2.2e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29634 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 1.13e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29635 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 3.73e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29636 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 5.87e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29637 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 2.03e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29638 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 4.63e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29639 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 2.85e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29640 FUN_025220 354 282 95 132 122 ptg000019l:60675-75569 Q96AY4 1.32e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29641 FUN_025223 56 115 34 94 111 NA NA NA NA NA NA NA 29642 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 2.22e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29643 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 1.27e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29644 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 1.05e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29645 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 1.51e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29646 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 3.77e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29647 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 6.4e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29648 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 1.89e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29649 FUN_025225 1925 1369 50 550 756 ptg000019l:181014-188111 Q96AY4 2.02e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29650 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 6.36e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29651 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 2.5e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29652 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 1.22e-95 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29653 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 1.84e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29654 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 5.15e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29655 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 1.9e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29656 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 8.33e-48 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29657 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 8.89e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29658 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 7.12e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29659 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 2.12e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29660 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 1.43e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29661 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 9.97e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29662 FUN_025224 1355 721 214 935 504 ptg000019l:131765-171015 Q96AY4 6.03e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29663 FUN_025227 15 9 0 0 0 NA NA NA NA NA NA NA 29664 FUN_025226 4905 4919 396 220 196 ptg000019l:211885-219487 O89110 1.34e-40 Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10] Mus musculus (Mouse) activation of cysteine-type endopeptidase activity [GO:0097202]; activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; cardiac muscle tissue development [GO:0048738]; execution phase of apoptosis [GO:0097194]; extrinsic apoptotic signaling pathway [GO:0097191]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; heart development [GO:0007507]; hepatocyte apoptotic process [GO:0097284]; macrophage differentiation [GO:0030225]; necroptotic process [GO:0070266]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of necroptotic process [GO:0060546]; neural tube formation [GO:0001841]; positive regulation of apoptotic process [GO:0043065]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of macrophage differentiation [GO:0045651]; positive regulation of neuron death [GO:1901216]; positive regulation of proteolysis [GO:0045862]; protein processing [GO:0016485]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603]; pyroptosis [GO:0070269]; regulation of apoptotic signaling pathway [GO:2001233]; regulation of cytokine production [GO:0001817]; regulation of innate immune response [GO:0045088]; regulation of thymocyte apoptotic process [GO:0070243]; response to ethanol [GO:0045471]; response to tumor necrosis factor [GO:0034612]; self proteolysis [GO:0097264]; TRAIL-activated apoptotic signaling pathway [GO:0036462] GO:0001525; GO:0001817; GO:0001841; GO:0004175; GO:0004197; GO:0005123; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006508; GO:0006915; GO:0006919; GO:0007507; GO:0008233; GO:0008303; GO:0008625; GO:0016485; GO:0030225; GO:0030690; GO:0031264; GO:0031265; GO:0031625; GO:0032731; GO:0032991; GO:0034612; GO:0035877; GO:0036462; GO:0042802; GO:0043005; GO:0043065; GO:0043123; GO:0043124; GO:0044297; GO:0044877; GO:0045088; GO:0045121; GO:0045471; GO:0045651; GO:0045862; GO:0048738; GO:0051603; GO:0060546; GO:0070243; GO:0070266; GO:0070269; GO:0097110; GO:0097153; GO:0097190; GO:0097191; GO:0097194; GO:0097199; GO:0097200; GO:0097202; GO:0097264; GO:0097284; GO:0097342; GO:1901216; GO:2001233; GO:2001238 29665 FUN_029272 16 8 39 35 122 NA NA NA NA NA NA NA 29666 FUN_029273 128 218 132 158 223 NA NA NA NA NA NA NA 29667 FUN_000613 2763 1412 1305 2410 2408 NA NA NA NA NA NA NA 29668 FUN_000612 322 393 206 289 392 NA NA NA NA NA NA NA 29669 FUN_008244 291 345 166 1332 1187 ptg000002l:9612103-9613147 P07700 3.32e-24 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 29670 FUN_029276 1124 692 298 759 837 NA NA NA NA NA NA NA 29671 FUN_000614 1067 600 848 1126 958 NA NA NA NA NA NA NA 29672 FUN_029274 30 38 36 27 17 NA NA NA NA NA NA NA 29673 FUN_016779 3891 3700 1584 3300 1950 ptg000011l:7400656-7407654 Q8C015 4.04e-21 Serine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7) Mus musculus (Mouse) apoptotic process [GO:0006915]; cytoskeleton organization [GO:0007010]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; locomotory behavior [GO:0007626]; memory [GO:0007613]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; protein phosphorylation [GO:0006468]; regulation of MAPK cascade [GO:0043408] GO:0004674; GO:0005524; GO:0005654; GO:0005737; GO:0005739; GO:0006468; GO:0006915; GO:0007010; GO:0007612; GO:0007613; GO:0007626; GO:0035556; GO:0043408; GO:0045202; GO:0106310; GO:2001237 29674 FUN_029275 1406 1296 916 1211 629 NA NA NA NA NA NA NA 29675 FUN_014388 4 54 9 15 40 NA NA NA NA NA NA NA 29676 FUN_014389 39 23 24 14 43 NA NA NA NA NA NA NA 29677 FUN_014386 0 0 0 0 10 NA NA NA NA NA NA NA 29678 FUN_014387 4 0 4 0 17 NA NA NA NA NA NA NA 29679 FUN_014384 6 0 0 1 4 NA NA NA NA NA NA NA 29680 FUN_014385 18 0 10 0 42 NA NA NA NA NA NA NA 29681 FUN_032349 1870 1781 1137 1760 1164 NA NA NA NA NA NA NA 29682 FUN_016731 0 0 0 3 45 NA NA NA NA NA NA NA 29683 FUN_035218 551 506 222 491 469 NA NA NA NA NA NA NA 29684 FUN_035215 1684 1219 656 1146 709 NA NA NA NA NA NA NA 29685 FUN_035214 3587 4721 2202 4214 6192 NA NA NA NA NA NA NA 29686 FUN_035217 5020 4779 3236 5357 3021 ptg000025l:5229243-5247059 Q9ZUI6 8.77e-31 AP-1 complex subunit gamma-2 (Adaptor protein complex AP-1 large subunit gamma-2) (Adaptor-related protein complex 1 subunit gamma-2) (Clathrin assembly protein complex 1 gamma-2 large chain) (Gamma-adaptin 2) Arabidopsis thaliana (Mouse-ear cress) Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886] GO:0006886; GO:0006896; GO:0030121; GO:0035615; GO:0140312 29687 FUN_035217 5020 4779 3236 5357 3021 ptg000025l:5229243-5247059 Q9ZUI6 8.77e-31 AP-1 complex subunit gamma-2 (Adaptor protein complex AP-1 large subunit gamma-2) (Adaptor-related protein complex 1 subunit gamma-2) (Clathrin assembly protein complex 1 gamma-2 large chain) (Gamma-adaptin 2) Arabidopsis thaliana (Mouse-ear cress) Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886] GO:0006886; GO:0006896; GO:0030121; GO:0035615; GO:0140312 29688 FUN_035217 5020 4779 3236 5357 3021 ptg000025l:5229243-5247059 Q9ZUI6 8.77e-31 AP-1 complex subunit gamma-2 (Adaptor protein complex AP-1 large subunit gamma-2) (Adaptor-related protein complex 1 subunit gamma-2) (Clathrin assembly protein complex 1 gamma-2 large chain) (Gamma-adaptin 2) Arabidopsis thaliana (Mouse-ear cress) Golgi to vacuole transport [GO:0006896]; intracellular protein transport [GO:0006886] GO:0006886; GO:0006896; GO:0030121; GO:0035615; GO:0140312 29689 FUN_035216 4591 3762 2296 2872 2422 ptg000025l:5210657-5215175 Q9QY61 4.66e-36 Iroquois-class homeodomain protein IRX-4 (Homeodomain protein IRXA3) (Iroquois homeobox protein 4) Mus musculus (Mouse) cell development [GO:0048468]; establishment of animal organ orientation [GO:0048561]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005667; GO:0006357; GO:0007507; GO:0030182; GO:0048468; GO:0048561 29690 FUN_035211 206 243 7 189 105 NA NA NA NA NA NA NA 29691 FUN_035210 358 202 343 209 297 NA NA NA NA NA NA NA 29692 FUN_035213 215 197 176 120 220 ptg000025l:5167412-5175653 Q5RCP7 1.86e-44 Centrosomal protein of 76 kDa (Cep76) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of centriole replication [GO:0046599] GO:0005737; GO:0005814; GO:0046599 29693 FUN_035213 215 197 176 120 220 ptg000025l:5167412-5175653 Q5RCP7 4.7e-29 Centrosomal protein of 76 kDa (Cep76) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of centriole replication [GO:0046599] GO:0005737; GO:0005814; GO:0046599 29694 FUN_035213 215 197 176 120 220 ptg000025l:5167412-5175653 Q5RCP7 4.94e-24 Centrosomal protein of 76 kDa (Cep76) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of centriole replication [GO:0046599] GO:0005737; GO:0005814; GO:0046599 29695 FUN_035213 215 197 176 120 220 ptg000025l:5167412-5175653 Q5RCP7 1.08e-21 Centrosomal protein of 76 kDa (Cep76) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) regulation of centriole replication [GO:0046599] GO:0005737; GO:0005814; GO:0046599 29696 FUN_035212 318 131 100 256 196 NA NA NA NA NA NA NA 29697 FUN_036742 0 0 0 79 0 NA NA NA NA NA NA NA 29698 FUN_036740 18 18 12 4 26 NA NA NA NA NA NA NA 29699 FUN_036746 1015 838 797 997 976 NA NA NA NA NA NA NA 29700 FUN_036747 206 245 118 255 145 NA NA NA NA NA NA NA 29701 FUN_033029 0 0 25 0 0 NA NA NA NA NA NA NA 29702 FUN_036748 2141 1368 1089 1637 2218 ptg000026l:1329363-1344302 Q5ZJ85 1.88e-25 U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005681; GO:0016607; GO:0046540 29703 FUN_036748 2141 1368 1089 1637 2218 ptg000026l:1329363-1344302 Q5ZJ85 3.4e-24 U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005681; GO:0016607; GO:0046540 29704 FUN_036748 2141 1368 1089 1637 2218 ptg000026l:1329363-1344302 Q5ZJ85 3.4e-24 U4/U6 small nuclear ribonucleoprotein Prp3 (Pre-mRNA-splicing factor 3) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398]; spliceosomal tri-snRNP complex assembly [GO:0000244] GO:0000244; GO:0000398; GO:0005634; GO:0005681; GO:0016607; GO:0046540 29705 FUN_001692 67 40 54 70 172 NA NA NA NA NA NA NA 29706 FUN_001693 252 169 56 532 264 NA NA NA NA NA NA NA 29707 FUN_001691 78 59 171 203 76 NA NA NA NA NA NA NA 29708 FUN_039743 0 6 0 0 83 NA NA NA NA NA NA NA 29709 FUN_039741 23 0 34 0 88 NA NA NA NA NA NA NA 29710 FUN_039740 5 0 21 0 97 NA NA NA NA NA NA NA 29711 FUN_007229 444 140 253 372 36 NA NA NA NA NA NA NA 29712 FUN_039745 0 25 5 33 62 NA NA NA NA NA NA NA 29713 FUN_039744 80 7 0 115 104 NA NA NA NA NA NA NA 29714 FUN_007225 129 0 81 254 238 NA NA NA NA NA NA NA 29715 FUN_007224 0 0 0 17 0 NA NA NA NA NA NA NA 29716 FUN_007227 304 199 130 177 133 NA NA NA NA NA NA NA 29717 FUN_007226 18 15 11 15 9 NA NA NA NA NA NA NA 29718 FUN_007221 1749 651 1060 427 177 NA NA NA NA NA NA NA 29719 FUN_007223 84 0 53 6 17 NA NA NA NA NA NA NA 29720 FUN_007222 530 426 346 257 208 NA NA NA NA NA NA NA 29721 FUN_021830 0 0 5 0 19 NA NA NA NA NA NA NA 29722 FUN_021832 322 4 0 0 0 NA NA NA NA NA NA NA 29723 FUN_021834 0 0 9 0 0 NA NA NA NA NA NA NA 29724 FUN_016889 837 1395 285 560 355 NA NA NA NA NA NA NA 29725 FUN_031244 51 0 45 39 18 NA NA NA NA NA NA NA 29726 FUN_016888 132 1777 298 375 604 NA NA NA NA NA NA NA 29727 FUN_031242 735 467 572 429 394 ptg000023l:18473140-18483627 A0A0G2L7I0 1.32e-28 DNA-dependent metalloprotease SPRTN (EC 3.4.24.-) (Protein with SprT-like domain at the N terminus) (Spartan) Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to DNA damage stimulus [GO:0006974]; protein autoprocessing [GO:0016540]; protein-DNA covalent cross-linking repair [GO:0106300]; proteolysis [GO:0006508] GO:0000785; GO:0003690; GO:0003697; GO:0004222; GO:0005634; GO:0006508; GO:0006974; GO:0016540; GO:0031593; GO:0046872; GO:0106300 29728 FUN_031243 257 0 68 210 0 NA NA NA NA NA NA NA 29729 FUN_031240 3569 2460 1690 3119 2036 NA NA NA NA NA NA NA 29730 FUN_031241 3127 3885 1925 1771 884 NA NA NA NA NA NA NA 29731 FUN_031249 0 0 0 0 10 NA NA NA NA NA NA NA 29732 FUN_007594 0 107 0 0 0 NA NA NA NA NA NA NA 29733 FUN_007592 25 0 17 0 49 NA NA NA NA NA NA NA 29734 FUN_007599 28 14 29 26 0 NA NA NA NA NA NA NA 29735 FUN_007598 22 2 6 0 29 NA NA NA NA NA NA NA 29736 FUN_044153 1 2 9 14 27 NA NA NA NA NA NA NA 29737 FUN_040594 17 0 0 7 0 NA NA NA NA NA NA NA 29738 FUN_044150 5 7 13 6 118 NA NA NA NA NA NA NA 29739 FUN_006172 1301 1080 620 884 1293 ptg000001l:8733241-8737616 Q9QXG2 1.62e-93 Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein homolog) (Rab escort protein 1) (REP-1) Mus musculus (Mouse) blood vessel development [GO:0001568]; protein geranylgeranylation [GO:0018344]; protein targeting to membrane [GO:0006612]; small GTPase mediated signal transduction [GO:0007264]; vesicle-mediated transport [GO:0016192] GO:0001568; GO:0005092; GO:0005096; GO:0005634; GO:0005737; GO:0005829; GO:0005968; GO:0006612; GO:0007264; GO:0016192; GO:0018344; GO:0031267; GO:0044877 29740 FUN_006173 229 154 214 788 658 ptg000001l:8743950-8795430 Q99315 6.49e-135 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 29741 FUN_006170 67 41 18 35 73 NA NA NA NA NA NA NA 29742 FUN_006171 5625 2853 2849 2781 1405 ptg000001l:8727856-8730284 Q96CQ1 2.99e-94 Solute carrier family 25 member 36 Homo sapiens (Human) mitochondrial genome maintenance [GO:0000002]; mitochondrion organization [GO:0007005]; pyrimidine nucleotide import into mitochondrion [GO:1990519]; pyrimidine nucleotide transport [GO:0006864]; regulation of mitochondrial membrane potential [GO:0051881] GO:0000002; GO:0005739; GO:0005743; GO:0006864; GO:0007005; GO:0015218; GO:0051881; GO:1990519 29743 FUN_006176 221 58 23 263 14 NA NA NA NA NA NA NA 29744 FUN_006174 0 0 12 0 0 NA NA NA NA NA NA NA 29745 FUN_006175 223 676 93 1544 892 ptg000001l:8815213-8822390 Q7RTR2 2.81e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29746 FUN_006175 223 676 93 1544 892 ptg000001l:8815213-8822390 Q7RTR2 1.88e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29747 FUN_006175 223 676 93 1544 892 ptg000001l:8815213-8822390 Q7RTR2 1.52e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29748 FUN_006178 60 0 17 135 63 ptg000001l:8873316-8874687 Q7RTR2 6.18e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29749 FUN_006178 60 0 17 135 63 ptg000001l:8873316-8874687 Q7RTR2 1.2e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29750 FUN_006178 60 0 17 135 63 ptg000001l:8873316-8874687 Q7RTR2 5.02e-57 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29751 FUN_006178 60 0 17 135 63 ptg000001l:8873316-8874687 Q7RTR2 6.12e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29752 FUN_044151 76 280 97 248 602 NA NA NA NA NA NA NA 29753 FUN_037165 6 1 0 0 0 NA NA NA NA NA NA NA 29754 FUN_037164 18 10 0 7 0 NA NA NA NA NA NA NA 29755 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 3.97e-67 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29756 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 2.66e-64 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29757 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 4.38e-63 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29758 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 4.32e-61 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29759 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 3.49e-56 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29760 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 5.08e-50 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29761 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 2.28e-40 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29762 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 3.41e-35 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29763 FUN_037167 6191 4212 4050 5370 2860 ptg000026l:6550269-6553410 Q8TF32 9.47e-29 Zinc finger protein 431 Homo sapiens (Human) cell differentiation [GO:0030154]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006355; GO:0030154; GO:0043433; GO:0046872 29764 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 3.63e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29765 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 4.19e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29766 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 2.83e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29767 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 3.59e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29768 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 2.11e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29769 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 3.08e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29770 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 6.18e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29771 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 1.08e-41 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29772 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 1.41e-39 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29773 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 1.68e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29774 FUN_037166 1291 149 387 318 195 ptg000026l:6534172-6539434 P0CI65 1.75e-34 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 29775 FUN_037161 25 0 2 0 2 NA NA NA NA NA NA NA 29776 FUN_022169 5 12 1 13 17 NA NA NA NA NA NA NA 29777 FUN_037163 62 0 0 0 0 NA NA NA NA NA NA NA 29778 FUN_022168 0 0 0 44 0 ptg000016l:5844022-5845216 B8UU78 1.55e-42 EGF and laminin G domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29779 FUN_037169 126 159 58 88 41 NA NA NA NA NA NA NA 29780 FUN_037168 2 0 2 0 118 NA NA NA NA NA NA NA 29781 FUN_032535 452 654 490 451 641 ptg000023l:32989807-33014948 Q5U374 1.66e-55 Kelch-like protein 12 Danio rerio (Zebrafish) (Brachydanio rerio) anterior/posterior pattern specification [GO:0009952]; convergent extension involved in axis elongation [GO:0060028]; COPII vesicle coating [GO:0048208]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; neural crest cell development [GO:0014032]; neural crest formation [GO:0014029]; protein monoubiquitination [GO:0006513]; Wnt signaling pathway [GO:0016055] GO:0006513; GO:0006888; GO:0009952; GO:0014029; GO:0014032; GO:0016055; GO:0030127; GO:0030134; GO:0031463; GO:0048208; GO:0060028 29782 FUN_032534 3485 5586 5815 9722 5400 NA NA NA NA NA NA NA 29783 FUN_032537 16 47 14 7 71 ptg000023l:33025424-33026612 Q9EQD2 2.09e-21 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 29784 FUN_032531 44 18 19 14 0 NA NA NA NA NA NA NA 29785 FUN_032530 9 0 0 11 46 NA NA NA NA NA NA NA 29786 FUN_032533 894 336 129 330 266 ptg000023l:32976143-32977949 Q55CD9 3.2e-78 Probable NADH dehydrogenase (EC 7.1.1.2) Dictyostelium discoideum (Social amoeba) NADH oxidation [GO:0006116] GO:0006116; GO:0008137 29787 FUN_032533 894 336 129 330 266 ptg000023l:32976143-32977949 Q55CD9 4.65e-30 Probable NADH dehydrogenase (EC 7.1.1.2) Dictyostelium discoideum (Social amoeba) NADH oxidation [GO:0006116] GO:0006116; GO:0008137 29788 FUN_032532 0 16 0 18 54 NA NA NA NA NA NA NA 29789 FUN_044154 6 17 46 55 137 NA NA NA NA NA NA NA 29790 FUN_041807 91 65 198 72 46 NA NA NA NA NA NA NA 29791 FUN_041806 12 20 13 5 0 NA NA NA NA NA NA NA 29792 FUN_041804 3 0 0 6 0 NA NA NA NA NA NA NA 29793 FUN_041803 0 24 10 11 19 NA NA NA NA NA NA NA 29794 FUN_041802 439 1236 7 978 340 NA NA NA NA NA NA NA 29795 FUN_041801 1298 1211 120 2278 1441 ptg000035l:7707614-7721091 P21328 1.99e-24 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 29796 FUN_041800 1393 2128 31 4199 2061 NA NA NA NA NA NA NA 29797 FUN_041809 478 222 277 378 361 ptg000035l:7833651-7848760 O00370 2.13e-27 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 29798 FUN_041808 658 361 389 377 381 NA NA NA NA NA NA NA 29799 FUN_001335 220 114 199 359 236 NA NA NA NA NA NA NA 29800 FUN_033663 0 1 2 1 7 NA NA NA NA NA NA NA 29801 FUN_001337 7027 6383 7697 7586 4824 NA NA NA NA NA NA NA 29802 FUN_033661 0 2 19 7 44 NA NA NA NA NA NA NA 29803 FUN_001331 506 922 679 540 415 NA NA NA NA NA NA NA 29804 FUN_033667 0 0 10 1 1 NA NA NA NA NA NA NA 29805 FUN_001333 1240 1197 479 1206 508 NA NA NA NA NA NA NA 29806 FUN_033665 42 19 30 18 87 NA NA NA NA NA NA NA 29807 FUN_033668 13990 13161 7690 8283 6362 NA NA NA NA NA NA NA 29808 FUN_033669 4551 3696 3482 6506 3239 NA NA NA NA NA NA NA 29809 FUN_001338 1278 881 615 2711 2514 NA NA NA NA NA NA NA 29810 FUN_042815 333 211 234 269 174 ptg000047l:413518-424845 Q8C627 3.59e-58 Protein FAM221B Mus musculus (Mouse) NA NA 29811 FUN_002679 317 130 0 181 48 NA NA NA NA NA NA NA 29812 FUN_042814 4346 2942 2763 3909 2978 ptg000047l:378203-409134 O00160 1.36e-45 Unconventional myosin-If (Myosin-Ie) Homo sapiens (Human) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003779; GO:0005516; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005902; GO:0007015; GO:0015629; GO:0016461; GO:0030050; GO:0031982; GO:0051015 29813 FUN_042814 4346 2942 2763 3909 2978 ptg000047l:378203-409134 O00160 1.36e-45 Unconventional myosin-If (Myosin-Ie) Homo sapiens (Human) actin filament organization [GO:0007015]; vesicle transport along actin filament [GO:0030050] GO:0000146; GO:0003779; GO:0005516; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0005902; GO:0007015; GO:0015629; GO:0016461; GO:0030050; GO:0031982; GO:0051015 29814 FUN_002675 492 371 69 153 393 ntLink_8:5185664-5197204 B3EWZ3 5.04e-25 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29815 FUN_002675 492 371 69 153 393 ntLink_8:5185664-5197204 B3EWZ3 1.04e-23 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29816 FUN_002675 492 371 69 153 393 ntLink_8:5185664-5197204 B3EWZ3 5.61e-23 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29817 FUN_002675 492 371 69 153 393 ntLink_8:5185664-5197204 B3EWZ3 6.54e-22 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29818 FUN_002675 492 371 69 153 393 ntLink_8:5185664-5197204 B3EWZ3 6.54e-22 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29819 FUN_002675 492 371 69 153 393 ntLink_8:5185664-5197204 B3EWZ3 6.82e-22 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29820 FUN_002677 1712 1826 792 1343 1343 NA NA NA NA NA NA NA 29821 FUN_002676 0 0 7 24 30 NA NA NA NA NA NA NA 29822 FUN_002671 0 0 0 0 53 ntLink_8:5131302-5142189 B3EWZ3 2.55e-42 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29823 FUN_002671 0 0 0 0 53 ntLink_8:5131302-5142189 B3EWZ3 5.74e-42 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29824 FUN_002670 3456 3545 1569 1864 1767 NA NA NA NA NA NA NA 29825 FUN_002673 0 0 0 0 16 NA NA NA NA NA NA NA 29826 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 7.01e-124 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29827 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 7.01e-124 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29828 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 2.95e-98 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29829 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 5.65e-90 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29830 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 7.58e-90 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29831 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 4.81e-29 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29832 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 4.21e-28 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29833 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 8.68e-27 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29834 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 3.04e-26 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29835 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 4.87e-26 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29836 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 2.46e-25 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29837 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 2.77e-25 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29838 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 1.13e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29839 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 1.15e-24 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29840 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 1.38e-23 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29841 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 2.73e-22 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29842 FUN_002672 15263 9766 7231 22663 12617 ntLink_8:5144663-5166881 B3EWZ3 1.88e-21 Coadhesin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 29843 FUN_042816 3135 1461 2072 3460 2393 NA NA NA NA NA NA NA 29844 FUN_016771 679 499 1498 2283 35 NA NA NA NA NA NA NA 29845 FUN_042813 484 303 203 390 600 NA NA NA NA NA NA NA 29846 FUN_013512 15 102 47 87 0 ptg000008l:23548604-23555927 Q7RTR2 2.32e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29847 FUN_016772 440 14 1436 3398 11 NA NA NA NA NA NA NA 29848 FUN_013513 99 100 111 124 72 NA NA NA NA NA NA NA 29849 FUN_040080 66 69 32 97 88 NA NA NA NA NA NA NA 29850 FUN_040081 231 255 137 178 217 ptg000031l:3968873-3970425 Q99999 3.72e-50 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Homo sapiens (Human) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; myelination [GO:0042552]; protein N-linked glycosylation [GO:0006487]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0005886; GO:0006487; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0016020; GO:0042552; GO:0046486; GO:0050694 29851 FUN_003650 0 0 46 276 3 NA NA NA NA NA NA NA 29852 FUN_016778 882 749 616 1031 1183 NA NA NA NA NA NA NA 29853 FUN_003653 21 76 21 109 13 NA NA NA NA NA NA NA 29854 FUN_040623 0 0 25 0 42 NA NA NA NA NA NA NA 29855 FUN_010144 50 0 13 0 185 ptg000004l:15461213-15463319 Q6LAF1 2.88e-48 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 29856 FUN_017829 586 382 468 657 776 NA NA NA NA NA NA NA 29857 FUN_010146 0 0 0 2 36 ptg000004l:15469914-15474002 Q9J569 1e-22 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 29858 FUN_040627 6 1 1038 212 2 NA NA NA NA NA NA NA 29859 FUN_012726 0 12 0 8 0 NA NA NA NA NA NA NA 29860 FUN_012725 54 35 50 34 22 NA NA NA NA NA NA NA 29861 FUN_012720 0 0 14 0 32 NA NA NA NA NA NA NA 29862 FUN_012721 98 19 25 38 38 NA NA NA NA NA NA NA 29863 FUN_018830 5 21 0 0 88 NA NA NA NA NA NA NA 29864 FUN_006958 287 334 492 847 391 NA NA NA NA NA NA NA 29865 FUN_006959 1556 278 89 241 100 ptg000001l:18797392-18799306 Q9U6Y6 2.82e-30 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29866 FUN_006959 1556 278 89 241 100 ptg000001l:18797392-18799306 Q9U6Y6 1e-26 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29867 FUN_016438 340 380 263 288 261 NA NA NA NA NA NA NA 29868 FUN_018831 309 166 159 283 66 NA NA NA NA NA NA NA 29869 FUN_016436 1000 581 374 953 508 NA NA NA NA NA NA NA 29870 FUN_006955 60 6 62 0 160 ptg000001l:18762219-18765460 Q9U6Y6 1.42e-29 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29871 FUN_006955 60 6 62 0 160 ptg000001l:18762219-18765460 Q9U6Y6 1.03e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29872 FUN_016434 3224 1677 1524 2658 2046 NA NA NA NA NA NA NA 29873 FUN_006957 24 4 18 37 73 NA NA NA NA NA NA NA 29874 FUN_016432 4375 2814 2025 3291 3015 NA NA NA NA NA NA NA 29875 FUN_006951 50 18 0 73 144 ptg000001l:18738342-18740673 Q9U6Y6 2.35e-29 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29876 FUN_006951 50 18 0 73 144 ptg000001l:18738342-18740673 Q9U6Y6 6.78e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29877 FUN_006952 56 0 0 0 16 ptg000001l:18746864-18747516 Q9U6Y6 4.5e-31 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29878 FUN_006952 56 0 0 0 16 ptg000001l:18746864-18747516 Q9U6Y6 5.93e-28 GFP-like fluorescent chromoprotein amFP486 Anemonia manjano (Sea anemone) bioluminescence [GO:0008218]; generation of precursor metabolites and energy [GO:0006091] GO:0006091; GO:0008218 29879 FUN_016431 759 630 332 615 365 NA NA NA NA NA NA NA 29880 FUN_018833 0 0 18 7 49 NA NA NA NA NA NA NA 29881 FUN_018834 0 0 10 0 7 NA NA NA NA NA NA NA 29882 FUN_018835 1006 534 761 1047 1178 ptg000012l:14110826-14129707 Q9C0G6 3.23e-47 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 29883 FUN_018835 1006 534 761 1047 1178 ptg000012l:14110826-14129707 Q9C0G6 2.14e-33 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 29884 FUN_018835 1006 534 761 1047 1178 ptg000012l:14110826-14129707 Q9C0G6 2.01e-30 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 29885 FUN_018835 1006 534 761 1047 1178 ptg000012l:14110826-14129707 Q9C0G6 2.09e-23 Dynein axonemal heavy chain 6 (Axonemal beta dynein heavy chain 6) (Ciliary dynein heavy chain 6) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 29886 FUN_017824 174 145 104 103 125 NA NA NA NA NA NA NA 29887 FUN_017825 9 4 13 44 26 NA NA NA NA NA NA NA 29888 FUN_035158 266 185 161 82 231 NA NA NA NA NA NA NA 29889 FUN_035159 220 76 138 390 197 NA NA NA NA NA NA NA 29890 FUN_035152 798 881 432 583 283 NA NA NA NA NA NA NA 29891 FUN_035153 6517 3162 3822 4584 4528 NA NA NA NA NA NA NA 29892 FUN_035150 1205 189 59 211 315 NA NA NA NA NA NA NA 29893 FUN_035151 1057 1260 521 1228 861 ptg000025l:4496555-4553725 P14381 2.19e-112 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 29894 FUN_035157 24 37 16 0 52 NA NA NA NA NA NA NA 29895 FUN_035154 3744 2674 1385 4281 4248 NA NA NA NA NA NA NA 29896 FUN_035155 604 120 316 230 428 NA NA NA NA NA NA NA 29897 FUN_016380 300 344 160 494 309 NA NA NA NA NA NA NA 29898 FUN_016381 1550 939 355 1149 680 ptg000011l:2501129-2507415 Q86TI4 9.38e-49 WD repeat-containing protein 86 Homo sapiens (Human) NA NA 29899 FUN_003209 17 18 39 15 37 NA NA NA NA NA NA NA 29900 FUN_016384 2196 1910 1129 1257 1201 NA NA NA NA NA NA NA 29901 FUN_016385 2186 2287 1888 2469 2199 NA NA NA NA NA NA NA 29902 FUN_016386 2137 973 789 830 1138 NA NA NA NA NA NA NA 29903 FUN_016387 1205 299 586 647 992 NA NA NA NA NA NA NA 29904 FUN_016388 4183 4352 1823 3173 2659 NA NA NA NA NA NA NA 29905 FUN_016389 321 350 73 118 28 NA NA NA NA NA NA NA 29906 FUN_003201 0 0 20 0 4 NA NA NA NA NA NA NA 29907 FUN_013098 53 29 91 25 51 NA NA NA NA NA NA NA 29908 FUN_013097 183 94 141 113 210 NA NA NA NA NA NA NA 29909 FUN_013096 13 3 38 0 135 NA NA NA NA NA NA NA 29910 FUN_028754 0 0 0 0 58 NA NA NA NA NA NA NA 29911 FUN_028755 0 0 0 0 6 NA NA NA NA NA NA NA 29912 FUN_028751 11 3 0 13 24 NA NA NA NA NA NA NA 29913 FUN_001527 362 375 130 324 285 ntLink_6:13265322-13266519 P56718 1.94e-29 Orexin/Hypocretin receptor type 1 (Hypocretin receptor type 1) (Orexin receptor type 1) (Ox-1-R) (Ox1-R) (Ox1R) Rattus norvegicus (Rat) feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007218; GO:0007631; GO:0016499; GO:0017046; GO:0051480; GO:0070374 29914 FUN_016049 6254 6113 3272 8364 2512 NA NA NA NA NA NA NA 29915 FUN_016047 1418 975 642 2210 832 ptg000010l:1031553-1039407 O43272 3.54e-33 Proline dehydrogenase 1, mitochondrial (EC 1.5.5.2) (Proline oxidase) (Proline oxidase 2) (p53-induced gene 6 protein) Homo sapiens (Human) 4-hydroxyproline catabolic process [GO:0019470]; intrinsic apoptotic signaling pathway in response to oxidative stress [GO:0008631]; positive regulation of cell death [GO:0010942]; proline catabolic process [GO:0006562]; proline catabolic process to glutamate [GO:0010133]; proline metabolic process [GO:0006560] GO:0004657; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0006560; GO:0006562; GO:0008631; GO:0010133; GO:0010942; GO:0019470; GO:0043231; GO:0071949 29916 FUN_043519 2382 1707 996 1506 1856 NA NA NA NA NA NA NA 29917 FUN_043518 27063 32310 13157 23615 18076 ptg000047l:9494984-9499837 G1TFM5 3.56e-41 NA NA NA NA 29918 FUN_043517 6947 5803 3498 5081 2721 NA NA NA NA NA NA NA 29919 FUN_043515 8162 8414 4359 7291 5163 NA NA NA NA NA NA NA 29920 FUN_043514 6 30 56 60 25 NA NA NA NA NA NA NA 29921 FUN_043513 478 502 265 448 296 NA NA NA NA NA NA NA 29922 FUN_043512 1770 1740 641 4965 2447 NA NA NA NA NA NA NA 29923 FUN_043511 2585 1635 875 4011 3515 ptg000047l:9433117-9449909 D4A1F2 8.38e-44 [F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (MICAL C-terminal-like protein) (Mical-cL) (Molecule interacting with CasL protein 2) (MICAL-2) (Protein RSB-11-77) Rattus norvegicus (Rat) actin filament depolymerization [GO:0030042]; cytoskeleton organization [GO:0007010]; heart development [GO:0007507]; heart looping [GO:0001947]; positive regulation of transcription by RNA polymerase II [GO:0045944]; sulfur oxidation [GO:0019417] GO:0001947; GO:0003779; GO:0005634; GO:0005737; GO:0007010; GO:0007507; GO:0016174; GO:0016491; GO:0016709; GO:0019417; GO:0030042; GO:0045944; GO:0046872; GO:0051019; GO:0071949 29924 FUN_043510 2079 1241 751 1234 792 ptg000047l:9423314-9430308 Q0VFN8 5.48e-50 Cilia- and flagella-associated protein 157 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sperm axoneme assembly [GO:0007288] GO:0005737; GO:0007288; GO:0008017; GO:0036064 29925 FUN_043510 2079 1241 751 1234 792 ptg000047l:9423314-9430308 Q0VFN8 3.44e-25 Cilia- and flagella-associated protein 157 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) sperm axoneme assembly [GO:0007288] GO:0005737; GO:0007288; GO:0008017; GO:0036064 29926 FUN_042324 0 0 0 0 23 NA NA NA NA NA NA NA 29927 FUN_042648 27 14 13 12 34 NA NA NA NA NA NA NA 29928 FUN_042649 894 557 468 950 1069 NA NA NA NA NA NA NA 29929 FUN_042644 294 380 232 221 183 NA NA NA NA NA NA NA 29930 FUN_016043 74 16 24 99 31 NA NA NA NA NA NA NA 29931 FUN_042646 104 115 63 108 113 NA NA NA NA NA NA NA 29932 FUN_042640 45 0 25 12 117 NA NA NA NA NA NA NA 29933 FUN_042641 1413 1285 636 1051 684 NA NA NA NA NA NA NA 29934 FUN_042642 2448 1429 1186 2299 2344 NA NA NA NA NA NA NA 29935 FUN_042643 64 51 0 32 9 NA NA NA NA NA NA NA 29936 FUN_016041 53 31 51 57 59 NA NA NA NA NA NA NA 29937 FUN_042320 323 285 420 203 218 NA NA NA NA NA NA NA 29938 FUN_041297 66 63 132 34 83 NA NA NA NA NA NA NA 29939 FUN_009329 0 0 21 3 65 NA NA NA NA NA NA NA 29940 FUN_009327 7 0 7 18 58 ptg000004l:5357601-5360466 P25291 9.61e-22 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 29941 FUN_009324 0 0 0 0 26 NA NA NA NA NA NA NA 29942 FUN_009325 0 0 0 0 13 ptg000004l:5340323-5342721 P27590 2.17e-24 Uromodulin (Tamm-Horsfall urinary glycoprotein) (THP) [Cleaved into: Uromodulin, secreted form] Rattus norvegicus (Rat) antibacterial innate immune response [GO:0140367]; apoptotic process [GO:0006915]; apoptotic signaling pathway [GO:0097190]; autophagy [GO:0006914]; calcium ion homeostasis [GO:0055074]; cellular calcium ion homeostasis [GO:0006874]; cellular chloride ion homeostasis [GO:0030644]; cellular phosphate ion homeostasis [GO:0030643]; cellular response to unfolded protein [GO:0034620]; cellular sodium ion homeostasis [GO:0006883]; chaperone-mediated protein folding [GO:0061077]; chemical homeostasis [GO:0048878]; chloride ion homeostasis [GO:0055064]; citric acid secretion [GO:0046720]; collecting duct development [GO:0072044]; connective tissue replacement [GO:0097709]; creatinine homeostasis [GO:0097273]; defense response to Gram-negative bacterium [GO:0050829]; endoplasmic reticulum organization [GO:0007029]; gene expression [GO:0010467]; glomerular filtration [GO:0003094]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; inflammatory response [GO:0006954]; ion homeostasis [GO:0050801]; juxtaglomerular apparatus development [GO:0072051]; kidney development [GO:0001822]; leukocyte cell-cell adhesion [GO:0007159]; lipid metabolic process [GO:0006629]; loop of Henle development [GO:0072070]; metanephric ascending thin limb development [GO:0072218]; metanephric distal convoluted tubule development [GO:0072221]; metanephric thick ascending limb development [GO:0072233]; micturition [GO:0060073]; multicellular organismal homeostasis [GO:0048871]; multicellular organismal response to stress [GO:0033555]; neutrophil migration [GO:1990266]; organ or tissue specific immune response [GO:0002251]; peptidyl-threonine phosphorylation [GO:0018107]; phosphate ion homeostasis [GO:0055062]; potassium ion homeostasis [GO:0055075]; protein localization to vacuole [GO:0072665]; protein phosphorylation [GO:0006468]; protein transport into plasma membrane raft [GO:0044861]; regulation of blood pressure [GO:0008217]; regulation of protein transport [GO:0051223]; regulation of urine volume [GO:0035809]; renal sodium ion absorption [GO:0070294]; renal urate salt excretion [GO:0097744]; renal water homeostasis [GO:0003091]; response to endoplasmic reticulum stress [GO:0034976]; response to lipopolysaccharide [GO:0032496]; response to organic substance [GO:0010033]; response to unfolded protein [GO:0006986]; response to water deprivation [GO:0009414]; response to xenobiotic stimulus [GO:0009410]; RNA splicing [GO:0008380]; sodium ion homeostasis [GO:0055078]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; ubiquitin-dependent ERAD pathway [GO:0030433]; urate transport [GO:0015747]; urea transmembrane transport [GO:0071918]; water homeostasis [GO:0030104] GO:0000922; GO:0001822; GO:0002251; GO:0003091; GO:0003094; GO:0005201; GO:0005509; GO:0005615; GO:0005783; GO:0005794; GO:0005886; GO:0005929; GO:0006468; GO:0006629; GO:0006874; GO:0006883; GO:0006914; GO:0006915; GO:0006954; GO:0006986; GO:0007029; GO:0007157; GO:0007159; GO:0008217; GO:0008380; GO:0009410; GO:0009414; GO:0009986; GO:0010033; GO:0010467; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0018107; GO:0019864; GO:0030104; GO:0030433; GO:0030643; GO:0030644; GO:0031410; GO:0032496; GO:0033209; GO:0033555; GO:0034620; GO:0034976; GO:0035809; GO:0044861; GO:0045121; GO:0045177; GO:0046720; GO:0048871; GO:0048878; GO:0050801; GO:0050829; GO:0051223; GO:0055062; GO:0055064; GO:0055074; GO:0055075; GO:0055078; GO:0060073; GO:0060170; GO:0061077; GO:0070294; GO:0071918; GO:0072044; GO:0072051; GO:0072070; GO:0072218; GO:0072221; GO:0072233; GO:0072665; GO:0097190; GO:0097273; GO:0097709; GO:0097744; GO:0140367; GO:1990266 29943 FUN_009322 89 15 47 28 169 NA NA NA NA NA NA NA 29944 FUN_009320 37 0 50 0 149 NA NA NA NA NA NA NA 29945 FUN_009321 56 0 27 30 148 ptg000004l:5253490-5256035 P25291 1.44e-22 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 29946 FUN_033987 1150 476 419 995 1002 NA NA NA NA NA NA NA 29947 FUN_004232 499 333 485 694 735 NA NA NA NA NA NA NA 29948 FUN_004231 703 739 587 531 274 NA NA NA NA NA NA NA 29949 FUN_033984 101 201 259 681 398 NA NA NA NA NA NA NA 29950 FUN_004237 84 51 53 86 78 NA NA NA NA NA NA NA 29951 FUN_004236 866 1142 430 851 431 ntLink_8:20994563-20999293 Q8R507 4.68e-23 Ribitol-5-phosphate transferase FKTN (EC 2.7.8.-) (Fukutin) (Fukuyama-type congenital muscular dystrophy protein) (Ribitol-5-phosphate transferase) Mus musculus (Mouse) negative regulation of cell population proliferation [GO:0008285]; negative regulation of JNK cascade [GO:0046329]; neuron migration [GO:0001764]; protein glycosylation [GO:0006486]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269]; regulation of protein glycosylation [GO:0060049] GO:0000139; GO:0001764; GO:0005634; GO:0005783; GO:0005794; GO:0005801; GO:0006486; GO:0006493; GO:0008285; GO:0016780; GO:0035269; GO:0046329; GO:0060049 29952 FUN_033981 211 312 251 730 300 ptg000024l:3365655-3367064 A7S4N4 1.2e-27 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 29953 FUN_033980 652 281 294 1629 1155 NA NA NA NA NA NA NA 29954 FUN_022619 2051 1383 1050 1814 1058 NA NA NA NA NA NA NA 29955 FUN_022618 76 71 68 98 44 NA NA NA NA NA NA NA 29956 FUN_022615 1007 358 376 638 280 ptg000016l:11433071-11434993 P97812 4.13e-34 Indian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product] Mus musculus (Mouse) bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye development [GO:0043010]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; endochondral bone morphogenesis [GO:0060350]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; morphogenesis of a branching structure [GO:0001763]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoprocessing [GO:0016540]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vasculature development [GO:0001944]; vitelline membrane formation [GO:0030704] GO:0000139; GO:0001501; GO:0001503; GO:0001569; GO:0001649; GO:0001701; GO:0001708; GO:0001763; GO:0001944; GO:0001947; GO:0002053; GO:0002062; GO:0003382; GO:0003406; GO:0003413; GO:0005113; GO:0005509; GO:0005576; GO:0005615; GO:0005789; GO:0005886; GO:0006029; GO:0007224; GO:0007267; GO:0007389; GO:0008233; GO:0008283; GO:0008284; GO:0009612; GO:0009880; GO:0010468; GO:0016539; GO:0016540; GO:0030704; GO:0031012; GO:0031016; GO:0032331; GO:0032355; GO:0032967; GO:0033085; GO:0033088; GO:0033089; GO:0034189; GO:0035264; GO:0035988; GO:0040008; GO:0042733; GO:0043010; GO:0043066; GO:0045453; GO:0045880; GO:0045944; GO:0046638; GO:0046639; GO:0048074; GO:0048469; GO:0048557; GO:0048596; GO:0048666; GO:0048745; GO:0050679; GO:0051216; GO:0060135; GO:0060220; GO:0060323; GO:0060350; GO:0061053; GO:0072498; GO:0090136; GO:0097264; GO:0097421; GO:0140853 29957 FUN_022615 1007 358 376 638 280 ptg000016l:11433071-11434993 P97812 3.19e-25 Indian hedgehog protein (IHH) (EC 3.1.-.-) (HHG-2) [Cleaved into: Indian hedgehog protein N-product] Mus musculus (Mouse) bone resorption [GO:0045453]; branching involved in blood vessel morphogenesis [GO:0001569]; camera-type eye development [GO:0043010]; camera-type eye photoreceptor cell fate commitment [GO:0060220]; cartilage development [GO:0051216]; cell fate specification [GO:0001708]; cell maturation [GO:0048469]; cell population proliferation [GO:0008283]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte differentiation involved in endochondral bone morphogenesis [GO:0003413]; chondrocyte proliferation [GO:0035988]; embryonic camera-type eye morphogenesis [GO:0048596]; embryonic digestive tract morphogenesis [GO:0048557]; embryonic digit morphogenesis [GO:0042733]; embryonic pattern specification [GO:0009880]; embryonic skeletal joint development [GO:0072498]; endochondral bone morphogenesis [GO:0060350]; epithelial cell morphogenesis [GO:0003382]; epithelial cell-cell adhesion [GO:0090136]; head morphogenesis [GO:0060323]; heart looping [GO:0001947]; in utero embryonic development [GO:0001701]; intein-mediated protein splicing [GO:0016539]; liver regeneration [GO:0097421]; maternal process involved in female pregnancy [GO:0060135]; morphogenesis of a branching structure [GO:0001763]; multicellular organism growth [GO:0035264]; negative regulation of alpha-beta T cell differentiation [GO:0046639]; negative regulation of apoptotic process [GO:0043066]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of eye pigmentation [GO:0048074]; negative regulation of immature T cell proliferation in thymus [GO:0033088]; negative regulation of T cell differentiation in thymus [GO:0033085]; neuron development [GO:0048666]; ossification [GO:0001503]; osteoblast differentiation [GO:0001649]; pancreas development [GO:0031016]; pattern specification process [GO:0007389]; positive regulation of alpha-beta T cell differentiation [GO:0046638]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of mesenchymal cell proliferation [GO:0002053]; positive regulation of smoothened signaling pathway [GO:0045880]; positive regulation of T cell differentiation in thymus [GO:0033089]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein autoprocessing [GO:0016540]; proteoglycan metabolic process [GO:0006029]; regulation of gene expression [GO:0010468]; regulation of growth [GO:0040008]; response to estradiol [GO:0032355]; response to mechanical stimulus [GO:0009612]; retinal pigment epithelium development [GO:0003406]; self proteolysis [GO:0097264]; skeletal system development [GO:0001501]; smooth muscle tissue development [GO:0048745]; smoothened signaling pathway [GO:0007224]; somite development [GO:0061053]; vasculature development [GO:0001944]; vitelline membrane formation [GO:0030704] GO:0000139; GO:0001501; GO:0001503; GO:0001569; GO:0001649; GO:0001701; GO:0001708; GO:0001763; GO:0001944; GO:0001947; GO:0002053; GO:0002062; GO:0003382; GO:0003406; GO:0003413; GO:0005113; GO:0005509; GO:0005576; GO:0005615; GO:0005789; GO:0005886; GO:0006029; GO:0007224; GO:0007267; GO:0007389; GO:0008233; GO:0008283; GO:0008284; GO:0009612; GO:0009880; GO:0010468; GO:0016539; GO:0016540; GO:0030704; GO:0031012; GO:0031016; GO:0032331; GO:0032355; GO:0032967; GO:0033085; GO:0033088; GO:0033089; GO:0034189; GO:0035264; GO:0035988; GO:0040008; GO:0042733; GO:0043010; GO:0043066; GO:0045453; GO:0045880; GO:0045944; GO:0046638; GO:0046639; GO:0048074; GO:0048469; GO:0048557; GO:0048596; GO:0048666; GO:0048745; GO:0050679; GO:0051216; GO:0060135; GO:0060220; GO:0060323; GO:0060350; GO:0061053; GO:0072498; GO:0090136; GO:0097264; GO:0097421; GO:0140853 29958 FUN_022614 267 188 155 100 270 NA NA NA NA NA NA NA 29959 FUN_022617 1054 309 178 468 166 NA NA NA NA NA NA NA 29960 FUN_022616 1025 1041 561 1123 1148 NA NA NA NA NA NA NA 29961 FUN_022611 437 226 333 544 290 ptg000016l:11363300-11364956 Q1PRL4 3.5e-37 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 29962 FUN_022610 491 572 264 439 514 ptg000016l:11346089-11359490 Q1PRL4 9.21e-36 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Gallus gallus (Chicken) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 29963 FUN_022613 4539 3096 2510 4078 2814 ptg000016l:11371501-11405441 P14381 2.49e-112 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 29964 FUN_022612 0 0 0 7 11 NA NA NA NA NA NA NA 29965 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 1.14e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29966 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 5.43e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29967 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 7.88e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29968 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 2.23e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29969 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 2.86e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29970 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 1.84e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29971 FUN_031357 188 261 157 32 682 ptg000023l:20046702-20061015 Q7RTR2 2.66e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 29972 FUN_029931 18 8 0 0 60 NA NA NA NA NA NA NA 29973 FUN_029938 0 0 26 1 27 NA NA NA NA NA NA NA 29974 FUN_041293 0 3 9 0 36 NA NA NA NA NA NA NA 29975 FUN_010016 474 251 205 207 177 NA NA NA NA NA NA NA 29976 FUN_010017 781 413 351 504 485 NA NA NA NA NA NA NA 29977 FUN_010015 1680 1287 818 827 641 NA NA NA NA NA NA NA 29978 FUN_010019 2597 2807 1268 3884 2136 NA NA NA NA NA NA NA 29979 FUN_009818 27673 28017 7248 14935 9668 ptg000004l:12087489-12091566 Q8MIR4 4.23e-81 Bifunctional coenzyme A synthase (CoA synthase) (NBP) (POV-2) [Includes: Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT); Dephospho-CoA kinase (DPCK) (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (DPCOAK)] Sus scrofa (Pig) coenzyme A biosynthetic process [GO:0015937]; phosphorylation [GO:0016310] GO:0004140; GO:0004595; GO:0005524; GO:0005759; GO:0015937; GO:0016310 29980 FUN_009819 1150 617 848 430 454 ptg000004l:12091822-12102825 Q6IA69 3.86e-61 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0005829; GO:0009435; GO:0034627 29981 FUN_009819 1150 617 848 430 454 ptg000004l:12091822-12102825 Q6IA69 1.24e-48 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0005829; GO:0009435; GO:0034627 29982 FUN_009819 1150 617 848 430 454 ptg000004l:12091822-12102825 Q6IA69 2.07e-42 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0005829; GO:0009435; GO:0034627 29983 FUN_009819 1150 617 848 430 454 ptg000004l:12091822-12102825 Q6IA69 6.02e-27 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0005829; GO:0009435; GO:0034627 29984 FUN_009819 1150 617 848 430 454 ptg000004l:12091822-12102825 Q6IA69 4.73e-24 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0005829; GO:0009435; GO:0034627 29985 FUN_009819 1150 617 848 430 454 ptg000004l:12091822-12102825 Q6IA69 9.74e-22 Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (NAD(+) synthetase) Homo sapiens (Human) 'de novo' NAD biosynthetic process [GO:0034627]; NAD biosynthetic process [GO:0009435] GO:0003952; GO:0004359; GO:0005524; GO:0005737; GO:0005829; GO:0009435; GO:0034627 29986 FUN_009815 627 780 685 1477 1013 ptg000004l:12024712-12031316 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29987 FUN_009815 627 780 685 1477 1013 ptg000004l:12024712-12031316 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29988 FUN_009815 627 780 685 1477 1013 ptg000004l:12024712-12031316 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29989 FUN_009815 627 780 685 1477 1013 ptg000004l:12024712-12031316 Q96AY4 4.48e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29990 FUN_009815 627 780 685 1477 1013 ptg000004l:12024712-12031316 Q96AY4 1.12e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29991 FUN_009817 842 360 460 774 966 ptg000004l:12057914-12083691 P42325 7.12e-77 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] GO:0005509; GO:0045938; GO:1902848 29992 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 6.17e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29993 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 4.41e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29994 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 3.64e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29995 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 3.44e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29996 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 2.14e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29997 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 3.04e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29998 FUN_009811 16 238 270 599 28 ptg000004l:11924080-11928415 Q96AY4 3.84e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 29999 FUN_009812 40 78 29 168 42 ptg000004l:11973160-11979176 Q96AY4 1.61e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30000 FUN_009812 40 78 29 168 42 ptg000004l:11973160-11979176 Q96AY4 1.5e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30001 FUN_009812 40 78 29 168 42 ptg000004l:11973160-11979176 Q96AY4 4.27e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30002 FUN_009812 40 78 29 168 42 ptg000004l:11973160-11979176 Q96AY4 1.65e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30003 FUN_009812 40 78 29 168 42 ptg000004l:11973160-11979176 Q96AY4 6.5e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30004 FUN_009813 1 0 57 3 9 NA NA NA NA NA NA NA 30005 FUN_024510 187 0 74 130 386 NA NA NA NA NA NA NA 30006 FUN_024511 491 343 320 583 516 ptg000018l:7468034-7480209 P46023 1.06e-82 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 30007 FUN_032278 1253 565 740 580 868 NA NA NA NA NA NA NA 30008 FUN_032279 10 0 0 0 26 NA NA NA NA NA NA NA 30009 FUN_024514 180 19 90 80 206 ptg000018l:7518779-7569766 Q7LHG5 2.52e-65 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 30010 FUN_024514 180 19 90 80 206 ptg000018l:7518779-7569766 Q7LHG5 2.52e-65 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 30011 FUN_024517 378 301 391 363 550 ptg000018l:7611941-7623377 P46023 6.1e-75 G-protein coupled receptor GRL101 Lymnaea stagnalis (Great pond snail) (Helix stagnalis) NA GO:0004930; GO:0005886 30012 FUN_032272 317 244 244 579 83 ptg000023l:30403221-30406933 Q8N3Y7 2.22e-38 Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) Homo sapiens (Human) keratinocyte proliferation [GO:0043616]; negative regulation of histone acetylation [GO:0035067]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] GO:0000122; GO:0003714; GO:0004745; GO:0005634; GO:0005789; GO:0005811; GO:0016616; GO:0017053; GO:0031065; GO:0035067; GO:0042572; GO:0042574; GO:0043616; GO:0061629; GO:0140297 30013 FUN_032272 317 244 244 579 83 ptg000023l:30403221-30406933 Q8N3Y7 2.22e-21 Epidermal retinol dehydrogenase 2 (EPHD-2) (RDH-E2) (EC 1.1.1.105) (Retinal short-chain dehydrogenase reductase 2) (retSDR2) (Short-chain dehydrogenase/reductase family 16C member 5) Homo sapiens (Human) keratinocyte proliferation [GO:0043616]; negative regulation of histone acetylation [GO:0035067]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of histone deacetylation [GO:0031065]; retinal metabolic process [GO:0042574]; retinol metabolic process [GO:0042572] GO:0000122; GO:0003714; GO:0004745; GO:0005634; GO:0005789; GO:0005811; GO:0016616; GO:0017053; GO:0031065; GO:0035067; GO:0042572; GO:0042574; GO:0043616; GO:0061629; GO:0140297 30014 FUN_032273 0 17 65 43 5 ptg000023l:30408394-30412811 Q05A13 8.28e-41 Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-) Mus musculus (Mouse) NA GO:0005811; GO:0016616 30015 FUN_032270 8649 6174 4811 7430 3998 NA NA NA NA NA NA NA 30016 FUN_044310 0 0 0 33 0 NA NA NA NA NA NA NA 30017 FUN_032276 1432 1795 1209 1621 1311 NA NA NA NA NA NA NA 30018 FUN_032277 13184 19450 13285 23754 15863 NA NA NA NA NA NA NA 30019 FUN_032274 616 108 234 361 228 ptg000023l:30429804-30431288 A8E7N9 8.2e-42 Growth/differentiation factor 6-B (GDF-6-B) (Growth differentiation factor 6b) (Protein dynamo) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; SMAD protein signal transduction [GO:0060395] GO:0005125; GO:0005615; GO:0008083; GO:0010862; GO:0060395 30020 FUN_006759 5 45 41 0 46 NA NA NA NA NA NA NA 30021 FUN_015147 305 542 12 0 310 NA NA NA NA NA NA NA 30022 FUN_015146 273 295 298 557 494 NA NA NA NA NA NA NA 30023 FUN_015145 2297 2423 1341 2626 3413 ptg000009l:6724686-6743902 Q640I9 1.98e-56 Lysine-specific demethylase 2B (EC 1.14.11.27) (F-box and leucine-rich repeat protein 10) (F-box/LRR-repeat protein 10) (JmjC domain-containing histone demethylation protein 1B) ([Histone-H3]-lysine-36 demethylase 1B) Xenopus laevis (African clawed frog) chromatin organization [GO:0006325]; histone H3-K36 demethylation [GO:0070544] GO:0005634; GO:0005694; GO:0005730; GO:0006325; GO:0008270; GO:0019843; GO:0045322; GO:0051864; GO:0070544; GO:0140680 30024 FUN_015142 12 0 0 11 59 NA NA NA NA NA NA NA 30025 FUN_015141 0 0 0 12 4 NA NA NA NA NA NA NA 30026 FUN_015140 772 441 126 270 529 ptg000009l:6680138-6681560 Q5ZL05 4.14e-40 Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A) Gallus gallus (Chicken) adaptive immune response [GO:0002250]; positive regulation of calcium ion transport [GO:0051928]; store-operated calcium entry [GO:0002115] GO:0002115; GO:0002250; GO:0005886; GO:0015279; GO:0016020; GO:0051928 30027 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 4.93e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30028 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 5.62e-56 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30029 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 2.23e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30030 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 1.05e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30031 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 3.36e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30032 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 2.03e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30033 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 5.83e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30034 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 1.02e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30035 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 9.86e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30036 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 4.13e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30037 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 1.06e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30038 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 4.39e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30039 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 1.74e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30040 FUN_030042 105 54 74 22 457 ptg000023l:8667479-8719187 Q80XJ3 2.03e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 30041 FUN_015149 162 360 165 234 343 NA NA NA NA NA NA NA 30042 FUN_015148 29 337 46 16 184 NA NA NA NA NA NA NA 30043 FUN_006753 114 222 47 38 61 NA NA NA NA NA NA NA 30044 FUN_030041 177 928 15 89 221 ptg000023l:8637826-8645040 Q8VDU0 1.6e-29 G-protein-signaling modulator 2 (Pins homolog) Mus musculus (Mouse) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 30045 FUN_023183 5028 5815 3030 4751 3789 ptg000017l:4627166-4629552 Q7Z7H5 3e-30 Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3) Homo sapiens (Human) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123] GO:0005783; GO:0005789; GO:0005793; GO:0005794; GO:0006886; GO:0006888; GO:0007030; GO:0030134; GO:0043123 30046 FUN_023988 288 480 222 147 163 NA NA NA NA NA NA NA 30047 FUN_023987 37 24 0 5 18 ptg000018l:903164-904478 Q6PF45 2.76e-72 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 30048 FUN_023984 3646 2127 1674 3634 2943 ptg000018l:888690-897326 Q6AYC8 2.12e-27 SH2 domain-containing protein 4A Rattus norvegicus (Rat) NA GO:0005737; GO:0005829; GO:0019902 30049 FUN_023985 222 86 45 104 133 ptg000018l:898983-900321 Q6PF45 2.97e-67 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 30050 FUN_023982 2402 2218 1375 1839 1460 NA NA NA NA NA NA NA 30051 FUN_023983 2255 2351 1076 2312 1677 NA NA NA NA NA NA NA 30052 FUN_023980 18 37 5 20 51 NA NA NA NA NA NA NA 30053 FUN_023981 675 416 471 714 838 NA NA NA NA NA NA NA 30054 FUN_014813 685 589 381 458 195 NA NA NA NA NA NA NA 30055 FUN_014810 2085 1036 1734 1705 2438 NA NA NA NA NA NA NA 30056 FUN_019823 0 49 0 12 8 NA NA NA NA NA NA NA 30057 FUN_014816 961 601 706 994 528 NA NA NA NA NA NA NA 30058 FUN_014814 4666 5743 3109 3191 2616 NA NA NA NA NA NA NA 30059 FUN_014815 609 585 683 1007 938 NA NA NA NA NA NA NA 30060 FUN_014818 1491 172 62 1512 959 NA NA NA NA NA NA NA 30061 FUN_014819 88 0 43 0 487 NA NA NA NA NA NA NA 30062 FUN_013842 463 0 139 6 1021 NA NA NA NA NA NA NA 30063 FUN_004948 454 319 243 610 180 NA NA NA NA NA NA NA 30064 FUN_013361 2660 2087 1250 1349 1333 ptg000008l:21676507-21678127 P24409 6.79e-22 Ras-related protein Rab-10 (EC 3.6.5.2) Canis lupus familiaris (Dog) (Canis familiaris) axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005789; GO:0005794; GO:0005802; GO:0005886; GO:0005929; GO:0006893; GO:0006904; GO:0007409; GO:0008021; GO:0009306; GO:0016192; GO:0016197; GO:0017157; GO:0019003; GO:0030670; GO:0030859; GO:0031489; GO:0032593; GO:0032869; GO:0043001; GO:0043231; GO:0045200; GO:0055037; GO:0055038; GO:0072659; GO:1903361 30065 FUN_041390 785 562 418 339 619 NA NA NA NA NA NA NA 30066 FUN_038629 70 31 33 41 46 NA NA NA NA NA NA NA 30067 FUN_038628 3966 4029 2985 4355 3158 NA NA NA NA NA NA NA 30068 FUN_015854 41 0 0 9 0 NA NA NA NA NA NA NA 30069 FUN_020989 23 0 0 0 30 NA NA NA NA NA NA NA 30070 FUN_020988 0 0 0 0 53 NA NA NA NA NA NA NA 30071 FUN_020987 0 0 0 0 12 NA NA NA NA NA NA NA 30072 FUN_020986 0 1 0 0 14 NA NA NA NA NA NA NA 30073 FUN_014993 1186 1138 401 1234 703 ptg000009l:5080958-5084633 P51659 9.74e-128 Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] GO:0000038; GO:0001649; GO:0003857; GO:0004300; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0008209; GO:0008210; GO:0016020; GO:0016508; GO:0016853; GO:0033989; GO:0036111; GO:0036112; GO:0042803; GO:0044594; GO:0060009; GO:0106386 30074 FUN_014993 1186 1138 401 1234 703 ptg000009l:5080958-5084633 P51659 8.95e-30 Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] GO:0000038; GO:0001649; GO:0003857; GO:0004300; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0008209; GO:0008210; GO:0016020; GO:0016508; GO:0016853; GO:0033989; GO:0036111; GO:0036112; GO:0042803; GO:0044594; GO:0060009; GO:0106386 30075 FUN_014993 1186 1138 401 1234 703 ptg000009l:5080958-5084633 P51659 9.89e-29 Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] GO:0000038; GO:0001649; GO:0003857; GO:0004300; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0008209; GO:0008210; GO:0016020; GO:0016508; GO:0016853; GO:0033989; GO:0036111; GO:0036112; GO:0042803; GO:0044594; GO:0060009; GO:0106386 30076 FUN_014993 1186 1138 401 1234 703 ptg000009l:5080958-5084633 P51659 6.87e-25 Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) (Short chain dehydrogenase/reductase family 8C member 1) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)] Homo sapiens (Human) androgen metabolic process [GO:0008209]; estrogen metabolic process [GO:0008210]; fatty acid beta-oxidation [GO:0006635]; medium-chain fatty-acyl-CoA metabolic process [GO:0036112]; osteoblast differentiation [GO:0001649]; Sertoli cell development [GO:0060009]; very long-chain fatty acid metabolic process [GO:0000038]; very long-chain fatty-acyl-CoA metabolic process [GO:0036111] GO:0000038; GO:0001649; GO:0003857; GO:0004300; GO:0005777; GO:0005778; GO:0005782; GO:0005829; GO:0006635; GO:0008209; GO:0008210; GO:0016020; GO:0016508; GO:0016853; GO:0033989; GO:0036111; GO:0036112; GO:0042803; GO:0044594; GO:0060009; GO:0106386 30077 FUN_004434 1374 628 544 1487 1111 NA NA NA NA NA NA NA 30078 FUN_014992 1076 971 436 991 1261 ptg000009l:5072250-5080369 Q63448 5.39e-29 Peroxisomal acyl-coenzyme A oxidase 3 (EC 1.3.3.6) (Branched-chain acyl-CoA oxidase) (BRCACox) (Pristanoyl-CoA oxidase) Rattus norvegicus (Rat) fatty acid beta-oxidation using acyl-CoA oxidase [GO:0033540]; lipid homeostasis [GO:0055088] GO:0003997; GO:0005504; GO:0005777; GO:0016402; GO:0033540; GO:0050660; GO:0055088; GO:0071949 30079 FUN_012331 3729 1547 2231 2509 2275 ptg000008l:7947218-7962814 Q9VHA0 1.47e-22 Polycomb protein Scm (Sex comb on midleg protein) Drosophila melanogaster (Fruit fly) anterior/posterior axis specification [GO:0009948]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; follicle cell of egg chamber stalk formation [GO:0030713]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of growth [GO:0045926]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; ventral cord development [GO:0007419] GO:0003682; GO:0005634; GO:0005700; GO:0006357; GO:0007409; GO:0007419; GO:0008270; GO:0009948; GO:0022008; GO:0030708; GO:0030713; GO:0031507; GO:0042393; GO:0042802; GO:0043565; GO:0045892; GO:0045926; GO:0048749; GO:0140259 30080 FUN_012331 3729 1547 2231 2509 2275 ptg000008l:7947218-7962814 Q9VHA0 1.76e-21 Polycomb protein Scm (Sex comb on midleg protein) Drosophila melanogaster (Fruit fly) anterior/posterior axis specification [GO:0009948]; axonogenesis [GO:0007409]; compound eye development [GO:0048749]; follicle cell of egg chamber stalk formation [GO:0030713]; germarium-derived female germ-line cyst encapsulation [GO:0030708]; heterochromatin formation [GO:0031507]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of growth [GO:0045926]; neurogenesis [GO:0022008]; regulation of transcription by RNA polymerase II [GO:0006357]; ventral cord development [GO:0007419] GO:0003682; GO:0005634; GO:0005700; GO:0006357; GO:0007409; GO:0007419; GO:0008270; GO:0009948; GO:0022008; GO:0030708; GO:0030713; GO:0031507; GO:0042393; GO:0042802; GO:0043565; GO:0045892; GO:0045926; GO:0048749; GO:0140259 30081 FUN_023205 9498 27516 16585 16176 11609 NA NA NA NA NA NA NA 30082 FUN_023204 13 27 6 14 4 NA NA NA NA NA NA NA 30083 FUN_023207 8 0 0 34 0 ptg000017l:5014469-5015986 Q91770 6.97e-24 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 30084 FUN_023206 0 24 21 5 40 NA NA NA NA NA NA NA 30085 FUN_023201 42 43 7 47 24 NA NA NA NA NA NA NA 30086 FUN_023200 887 517 481 1040 712 NA NA NA NA NA NA NA 30087 FUN_023202 564 378 183 362 335 ptg000017l:4983967-4993468 O80528 3.94e-21 Serine/threonine-protein kinase haspin homolog (AtHaspin) (EC 2.7.11.1) Arabidopsis thaliana (Mouse-ear cress) intracellular signal transduction [GO:0035556]; mitotic cell cycle [GO:0000278]; protein phosphorylation [GO:0006468] GO:0000278; GO:0005524; GO:0005634; GO:0005694; GO:0005737; GO:0005856; GO:0006468; GO:0009524; GO:0035402; GO:0035556; GO:0048471; GO:0072354; GO:0106310 30088 FUN_023208 44 99 140 69 107 ptg000017l:5019679-5021093 Q9WYP5 4.31e-45 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) inositol metabolic process [GO:0006020]; NADPH regeneration [GO:0006740] GO:0000166; GO:0006020; GO:0006740; GO:0016491; GO:0050112 30089 FUN_012330 5575 8893 2528 4846 3072 NA NA NA NA NA NA NA 30090 FUN_014039 16 26 10 51 27 NA NA NA NA NA NA NA 30091 FUN_014035 0 0 0 0 10 NA NA NA NA NA NA NA 30092 FUN_014036 3 0 0 0 274 NA NA NA NA NA NA NA 30093 FUN_014032 0 0 0 59 45 NA NA NA NA NA NA NA 30094 FUN_014033 8 0 0 0 96 NA NA NA NA NA NA NA 30095 FUN_014991 882 373 553 668 461 ptg000009l:5060953-5070133 Q9BUZ4 2.94e-51 TNF receptor-associated factor 4 (EC 2.3.2.27) (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; apoptotic process [GO:0006915]; innate immune response [GO:0045087]; positive regulation of JNK cascade [GO:0046330]; positive regulation of protein kinase activity [GO:0045860]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; respiratory gaseous exchange by respiratory system [GO:0007585]; respiratory tube development [GO:0030323] GO:0001650; GO:0005164; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005923; GO:0006915; GO:0007250; GO:0007585; GO:0008270; GO:0016740; GO:0019901; GO:0030323; GO:0031625; GO:0031996; GO:0042802; GO:0042981; GO:0043122; GO:0043161; GO:0045087; GO:0045860; GO:0046330; GO:0048471; GO:0050699 30096 FUN_022556 49 39 35 147 32 NA NA NA NA NA NA NA 30097 FUN_022557 881 146 172 980 1329 ptg000016l:10511645-10532302 P25291 4.27e-26 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 30098 FUN_024899 54 0 0 3 97 NA NA NA NA NA NA NA 30099 FUN_024891 1152 1683 463 1609 769 ptg000018l:12269193-12270036 P52046 3.14e-29 Short-chain-enoyl-CoA hydratase (EC 4.2.1.150) (3-hydroxybutyryl-CoA dehydratase) (Crotonase) Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) butyrate metabolic process [GO:0019605] GO:0016829; GO:0019605 30100 FUN_024893 100 118 85 375 177 ptg000018l:12278430-12312400 M9NDE3 1.11e-25 Protein bark beetle (Protein anakonda) Drosophila melanogaster (Fruit fly) cell-cell junction maintenance [GO:0045217]; liquid clearance, open tracheal system [GO:0035002]; regulation of tube length, open tracheal system [GO:0035159]; response to endoplasmic reticulum stress [GO:0034976]; tricellular tight junction assembly [GO:1904274] GO:0005044; GO:0005912; GO:0005918; GO:0005923; GO:0016328; GO:0030246; GO:0034976; GO:0035002; GO:0035159; GO:0045217; GO:0061689; GO:1904274 30101 FUN_024892 11 9 0 0 0 NA NA NA NA NA NA NA 30102 FUN_024894 230 117 78 259 380 ptg000018l:12315002-12343983 Q9NYQ7 1.01e-24 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 30103 FUN_024894 230 117 78 259 380 ptg000018l:12315002-12343983 Q9NYQ7 7.47e-21 Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007186; GO:0016020; GO:0060071; GO:0098609 30104 FUN_022101 7 0 15 0 29 NA NA NA NA NA NA NA 30105 FUN_012337 308 376 196 618 570 ptg000008l:8048937-8054936 Q8CGS6 2.43e-128 DNA polymerase theta (EC 2.7.7.7) (Chromosome aberrations occurring spontaneously protein 1) (DNA polymerase eta) Mus musculus (Mouse) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0003682; GO:0003887; GO:0005524; GO:0005654; GO:0005694; GO:0005794; GO:0005829; GO:0006261; GO:0006281; GO:0006284; GO:0006302; GO:0006974; GO:0016446; GO:0017116; GO:0042802; GO:0051260; GO:0051575; GO:0097681; GO:2000042 30106 FUN_012337 308 376 196 618 570 ptg000008l:8048937-8054936 Q8CGS6 1.38e-22 DNA polymerase theta (EC 2.7.7.7) (Chromosome aberrations occurring spontaneously protein 1) (DNA polymerase eta) Mus musculus (Mouse) base-excision repair [GO:0006284]; cellular response to DNA damage stimulus [GO:0006974]; DNA repair [GO:0006281]; DNA-templated DNA replication [GO:0006261]; double-strand break repair [GO:0006302]; double-strand break repair via alternative nonhomologous end joining [GO:0097681]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; protein homooligomerization [GO:0051260]; somatic hypermutation of immunoglobulin genes [GO:0016446] GO:0003677; GO:0003682; GO:0003887; GO:0005524; GO:0005654; GO:0005694; GO:0005794; GO:0005829; GO:0006261; GO:0006281; GO:0006284; GO:0006302; GO:0006974; GO:0016446; GO:0017116; GO:0042802; GO:0051260; GO:0051575; GO:0097681; GO:2000042 30107 FUN_044217 39 135 44 128 294 NA NA NA NA NA NA NA 30108 FUN_022100 10 0 0 0 0 NA NA NA NA NA NA NA 30109 FUN_030167 0 10 8 3 8 NA NA NA NA NA NA NA 30110 FUN_021119 0 0 28 0 0 NA NA NA NA NA NA NA 30111 FUN_021113 0 0 0 0 11 NA NA NA NA NA NA NA 30112 FUN_021112 11174 10533 4771 8824 6101 NA NA NA NA NA NA NA 30113 FUN_021111 0 10 0 0 0 NA NA NA NA NA NA NA 30114 FUN_021110 0 0 5 0 26 NA NA NA NA NA NA NA 30115 FUN_021116 0 0 3 0 13 NA NA NA NA NA NA NA 30116 FUN_021114 0 6 0 0 45 NA NA NA NA NA NA NA 30117 FUN_043063 7 0 10 0 51 NA NA NA NA NA NA NA 30118 FUN_018838 12 0 11 15 16 NA NA NA NA NA NA NA 30119 FUN_017828 2099 2683 1800 2482 1646 NA NA NA NA NA NA NA 30120 FUN_017822 122 96 48 69 63 NA NA NA NA NA NA NA 30121 FUN_017823 139 181 42 110 123 NA NA NA NA NA NA NA 30122 FUN_018832 0 0 4 0 146 NA NA NA NA NA NA NA 30123 FUN_017821 695 547 214 486 259 NA NA NA NA NA NA NA 30124 FUN_017826 561 479 223 454 490 NA NA NA NA NA NA NA 30125 FUN_017827 4199 3573 1688 3360 2240 ptg000012l:817933-827610 Q6NVP8 1.47e-71 Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GDP-L-fucose metabolic process [GO:0046368]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0008424; GO:0017124; GO:0018279; GO:0032580; GO:0046368 30126 FUN_017827 4199 3573 1688 3360 2240 ptg000012l:817933-827610 Q6NVP8 1.96e-34 Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GDP-L-fucose metabolic process [GO:0046368]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0008424; GO:0017124; GO:0018279; GO:0032580; GO:0046368 30127 FUN_018836 243 84 312 232 353 ptg000012l:14130576-14153671 Q0VDD8 7.08e-26 Dynein axonemal heavy chain 14 (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0005524; GO:0005737; GO:0005874; GO:0005929; GO:0007018; GO:0008569; GO:0030286; GO:0045505; GO:0051959 30128 FUN_035398 0 0 17 65 33 ptg000025l:7020132-7023451 P26221 4.6e-33 Endoglucanase E-4 (EC 3.2.1.4) (Cellulase E-4) (Cellulase E4) (Endo-1,4-beta-glucanase E-4) Thermobifida fusca (Thermomonospora fusca) cellulose catabolic process [GO:0030245] GO:0008810; GO:0030245; GO:0030248 30129 FUN_035398 0 0 17 65 33 ptg000025l:7020132-7023451 P26221 1.56e-24 Endoglucanase E-4 (EC 3.2.1.4) (Cellulase E-4) (Cellulase E4) (Endo-1,4-beta-glucanase E-4) Thermobifida fusca (Thermomonospora fusca) cellulose catabolic process [GO:0030245] GO:0008810; GO:0030245; GO:0030248 30130 FUN_035399 0 25 31 0 21 NA NA NA NA NA NA NA 30131 FUN_011505 37 0 25 0 149 NA NA NA NA NA NA NA 30132 FUN_035390 9918 8602 7069 12651 9403 NA NA NA NA NA NA NA 30133 FUN_035391 0 0 20 14 14 NA NA NA NA NA NA NA 30134 FUN_035392 8563 7238 4125 10241 7573 NA NA NA NA NA NA NA 30135 FUN_035393 4509 1833 904 4046 2190 NA NA NA NA NA NA NA 30136 FUN_035394 87 50 29 38 55 NA NA NA NA NA NA NA 30137 FUN_035395 464 711 111 433 250 NA NA NA NA NA NA NA 30138 FUN_035396 35 14 37 22 53 NA NA NA NA NA NA NA 30139 FUN_035397 348 195 126 568 218 NA NA NA NA NA NA NA 30140 FUN_044213 39 76 85 123 246 NA NA NA NA NA NA NA 30141 FUN_043068 16 0 0 4 28 NA NA NA NA NA NA NA 30142 FUN_031899 316 209 404 427 635 NA NA NA NA NA NA NA 30143 FUN_031898 1407 1509 1051 868 771 ptg000023l:26588288-26589548 P17081 1.04e-37 Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005522; GO:0005525; GO:0005884; GO:0005886; GO:0006897; GO:0007163; GO:0007264; GO:0008286; GO:0008360; GO:0030036; GO:0030660; GO:0030866; GO:0032427; GO:0032869; GO:0032956; GO:0045121; GO:0045944; GO:0046039; GO:0046326; GO:0051491; GO:0070062; GO:1903077 30144 FUN_031897 49 38 0 30 129 ptg000023l:26578447-26585192 Q54BM3 2.26e-26 Mitochondrial substrate carrier family protein G (Solute carrier family 25 member 20 homolog A) Dictyostelium discoideum (Social amoeba) NA GO:0005743; GO:0022857 30145 FUN_031896 191 107 46 56 188 ptg000023l:26566105-26572357 Q54BM3 2.37e-25 Mitochondrial substrate carrier family protein G (Solute carrier family 25 member 20 homolog A) Dictyostelium discoideum (Social amoeba) NA GO:0005743; GO:0022857 30146 FUN_031895 2421 1902 1224 2472 1809 NA NA NA NA NA NA NA 30147 FUN_031894 357 116 255 424 338 NA NA NA NA NA NA NA 30148 FUN_031893 5731 2862 2878 4236 2670 NA NA NA NA NA NA NA 30149 FUN_031892 255 19 282 497 200 NA NA NA NA NA NA NA 30150 FUN_031891 25 48 23 29 7 NA NA NA NA NA NA NA 30151 FUN_031890 19 0 79 0 87 NA NA NA NA NA NA NA 30152 FUN_044156 1 0 4 3 6 NA NA NA NA NA NA NA 30153 FUN_030415 8 1 8 0 33 ptg000023l:10815070-10815833 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30154 FUN_030417 11 0 9 0 37 ptg000023l:10819120-10819883 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30155 FUN_030410 5 0 8 0 27 ptg000023l:10802928-10803691 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30156 FUN_030412 3 0 4 0 10 ptg000023l:10805889-10807557 P35067 7.2e-79 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30157 FUN_030413 0 0 1 0 6 ptg000023l:10809217-10811781 P84239 4.8e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30158 FUN_038623 3 18 0 6 74 NA NA NA NA NA NA NA 30159 FUN_038622 4313 7172 3082 4445 1904 NA NA NA NA NA NA NA 30160 FUN_038621 634 704 322 508 780 ptg000027l:9408487-9423142 Q95SX7 2.75e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30161 FUN_038621 634 704 322 508 780 ptg000027l:9408487-9423142 Q95SX7 2.75e-26 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30162 FUN_038620 26 57 30 41 27 NA NA NA NA NA NA NA 30163 FUN_038627 162 143 79 165 107 NA NA NA NA NA NA NA 30164 FUN_038626 775 806 1066 1438 717 NA NA NA NA NA NA NA 30165 FUN_038625 376 307 1863 971 343 NA NA NA NA NA NA NA 30166 FUN_038624 255 262 44 481 248 ptg000027l:9444815-9446056 P84875 4.37e-42 Carboxypeptidase inhibitor SmCI Sabellastarte magnifica (Feather duster) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0008191; GO:0010466 30167 FUN_038624 255 262 44 481 248 ptg000027l:9444815-9446056 P84875 1.98e-40 Carboxypeptidase inhibitor SmCI Sabellastarte magnifica (Feather duster) negative regulation of peptidase activity [GO:0010466] GO:0004867; GO:0005576; GO:0008191; GO:0010466 30168 FUN_004945 214 175 100 84 120 NA NA NA NA NA NA NA 30169 FUN_004944 92 21 19 0 28 NA NA NA NA NA NA NA 30170 FUN_004947 366 408 209 577 429 NA NA NA NA NA NA NA 30171 FUN_004946 16028 16974 5179 12963 10219 NA NA NA NA NA NA NA 30172 FUN_004941 1997 1905 624 1405 733 NA NA NA NA NA NA NA 30173 FUN_004940 4051 2940 1655 3581 2415 NA NA NA NA NA NA NA 30174 FUN_004943 46 13 45 35 200 NA NA NA NA NA NA NA 30175 FUN_004942 841 1551 401 718 588 NA NA NA NA NA NA NA 30176 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.21e-148 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30177 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.81e-144 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30178 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.88e-144 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30179 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.69e-143 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30180 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.08e-140 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30181 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.34e-140 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30182 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.66e-140 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30183 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.47e-138 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30184 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.71e-137 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30185 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.56e-132 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30186 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.14e-132 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30187 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.51e-131 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30188 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.01e-131 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30189 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.84e-127 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30190 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.97e-124 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30191 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.77e-112 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30192 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.05e-94 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30193 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.78e-69 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30194 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.15e-65 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30195 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.85e-56 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30196 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.02e-51 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30197 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.32e-51 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30198 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.03e-50 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30199 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.36e-50 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30200 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.81e-50 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30201 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.2e-48 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30202 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.07e-48 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30203 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.45e-48 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30204 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.31e-46 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30205 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.61e-46 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30206 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.43e-46 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30207 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.81e-45 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30208 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.46e-44 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30209 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2e-44 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30210 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.06e-44 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30211 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.2e-43 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30212 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.9e-43 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30213 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.87e-43 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30214 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.35e-42 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30215 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.66e-41 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30216 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.5e-41 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30217 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.47e-41 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30218 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.31e-40 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30219 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.19e-40 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30220 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.38e-39 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30221 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.44e-36 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30222 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.17e-36 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30223 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.28e-34 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30224 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.06e-34 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30225 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.37e-33 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30226 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.94e-32 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30227 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.65e-30 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30228 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.92e-30 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30229 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.16e-29 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30230 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.9e-29 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30231 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.14e-28 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30232 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.14e-28 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30233 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.77e-28 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30234 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.13e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30235 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.6e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30236 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.39e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30237 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.66e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30238 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.28e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30239 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.69e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30240 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.13e-27 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30241 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.71e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30242 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.88e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30243 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.94e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30244 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.35e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30245 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.41e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30246 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.22e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30247 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.44e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30248 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.33e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30249 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.74e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30250 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.26e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30251 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.64e-26 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30252 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.08e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30253 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.28e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30254 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.94e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30255 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.52e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30256 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.74e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30257 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.78e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30258 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.85e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30259 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.92e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30260 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.33e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30261 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.83e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30262 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.43e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30263 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.77e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30264 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.34e-25 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30265 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.05e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30266 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.08e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30267 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.34e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30268 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.44e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30269 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.58e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30270 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.7e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30271 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.72e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30272 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.13e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30273 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.19e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30274 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.73e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30275 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.8e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30276 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.34e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30277 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.26e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30278 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.48e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30279 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.64e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30280 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.11e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30281 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.67e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30282 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.51e-24 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30283 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.16e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30284 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.95e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30285 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.05e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30286 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.21e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30287 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.79e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30288 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.89e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30289 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.06e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30290 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.19e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30291 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.22e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30292 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.53e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30293 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.77e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30294 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.77e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30295 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.13e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30296 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.06e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30297 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.19e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30298 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.36e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30299 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.68e-23 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30300 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30301 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.27e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30302 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.48e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30303 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.58e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30304 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.89e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30305 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.14e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30306 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.36e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30307 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.4e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30308 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.75e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30309 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.77e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30310 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.84e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30311 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.22e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30312 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.39e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30313 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.39e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30314 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.44e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30315 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.5e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30316 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.77e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30317 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.21e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30318 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.35e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30319 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.42e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30320 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.46e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30321 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.12e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30322 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.18e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30323 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.06e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30324 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.84e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30325 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 8.99e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30326 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 9.94e-22 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30327 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.05e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30328 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.1e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30329 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.13e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30330 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.31e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30331 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.6e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30332 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.8e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30333 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 1.81e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30334 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30335 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.05e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30336 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.35e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30337 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.73e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30338 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 2.84e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30339 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.04e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30340 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.2e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30341 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.25e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30342 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 3.28e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30343 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 4.89e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30344 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.19e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30345 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.23e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30346 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.27e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30347 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.27e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30348 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 5.59e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30349 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.23e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30350 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 6.89e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30351 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.24e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30352 FUN_019134 16296 9140 11006 26812 22699 ptg000012l:17505103-17622410 A2ASS6 7.94e-21 Titin (EC 2.7.11.1) (Connectin) Mus musculus (Mouse) adult heart development [GO:0007512]; cardiac muscle cell development [GO:0055013]; cardiac muscle contraction [GO:0060048]; cardiac muscle hypertrophy [GO:0003300]; cardiac muscle tissue morphogenesis [GO:0055008]; cardiac myofibril assembly [GO:0055003]; detection of muscle stretch [GO:0035995]; forward locomotion [GO:0043056]; heart development [GO:0007507]; heart growth [GO:0060419]; heart morphogenesis [GO:0003007]; in utero embryonic development [GO:0001701]; muscle contraction [GO:0006936]; positive regulation of gene expression [GO:0010628]; positive regulation of protein secretion [GO:0050714]; protein kinase A signaling [GO:0010737]; regulation of catalytic activity [GO:0050790]; regulation of protein kinase activity [GO:0045859]; regulation of relaxation of cardiac muscle [GO:1901897]; response to calcium ion [GO:0051592]; sarcomere organization [GO:0045214]; sarcomerogenesis [GO:0048769]; skeletal muscle myosin thick filament assembly [GO:0030241]; skeletal muscle thin filament assembly [GO:0030240]; somitogenesis [GO:0001756]; striated muscle cell development [GO:0055002]; ventricular system development [GO:0021591] GO:0000794; GO:0001701; GO:0001756; GO:0002020; GO:0003007; GO:0003300; GO:0004674; GO:0004713; GO:0005200; GO:0005509; GO:0005516; GO:0005524; GO:0005859; GO:0005865; GO:0006936; GO:0007507; GO:0007512; GO:0008307; GO:0010628; GO:0010737; GO:0019899; GO:0019901; GO:0021591; GO:0030017; GO:0030018; GO:0030240; GO:0030241; GO:0030506; GO:0031430; GO:0031433; GO:0031672; GO:0031674; GO:0035995; GO:0042802; GO:0042805; GO:0043056; GO:0043621; GO:0045214; GO:0045859; GO:0048769; GO:0050714; GO:0050790; GO:0051015; GO:0051371; GO:0051592; GO:0055002; GO:0055003; GO:0055008; GO:0055013; GO:0060048; GO:0060419; GO:0097493; GO:0106310; GO:1901897; GO:1990733 30353 FUN_020791 12 0 17 0 42 NA NA NA NA NA NA NA 30354 FUN_020796 0 0 0 0 14 NA NA NA NA NA NA NA 30355 FUN_020794 15 0 0 0 45 NA NA NA NA NA NA NA 30356 FUN_036153 0 0 0 0 8 ptg000025l:15781414-15782786 O42412 1.92e-24 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 30357 FUN_036152 51 19 58 29 37 ptg000025l:15766831-15774112 O42412 7.81e-21 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 30358 FUN_036151 706 350 351 547 347 NA NA NA NA NA NA NA 30359 FUN_036150 2679 1010 909 1284 1053 NA NA NA NA NA NA NA 30360 FUN_036157 0 0 20 18 26 NA NA NA NA NA NA NA 30361 FUN_036156 1311 587 839 1050 1533 ptg000025l:15814251-15836665 P98195 1.28e-25 Probable phospholipid-transporting ATPase IIB (EC 7.6.2.1) (ATPase class II type 9B) Mus musculus (Mouse) endocytosis [GO:0006897]; phospholipid translocation [GO:0045332]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890] GO:0000287; GO:0005524; GO:0005768; GO:0005802; GO:0005886; GO:0006890; GO:0006897; GO:0016887; GO:0045332; GO:0048471; GO:0140326 30362 FUN_036155 4 28 0 0 1 ptg000025l:15810896-15812126 P35348 1.58e-38 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c) Homo sapiens (Human) activation of phospholipase C activity [GO:0007202]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adult heart development [GO:0007512]; aging [GO:0007568]; apoptotic process [GO:0006915]; calcium ion transport into cytosol [GO:0060402]; cell growth involved in cardiac muscle cell development [GO:0061049]; cell-cell signaling [GO:0007267]; G protein-coupled receptor signaling pathway [GO:0007186]; intracellular signal transduction [GO:0035556]; MAPK cascade [GO:0000165]; micturition [GO:0060073]; multicellular organism aging [GO:0010259]; negative regulation of autophagy [GO:0010507]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure [GO:0001985]; negative regulation of Rho protein signal transduction [GO:0035024]; neuron-glial cell signaling [GO:0150099]; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [GO:0001994]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; pilomotor reflex [GO:0097195]; positive regulation of action potential [GO:0045760]; positive regulation of cardiac muscle contraction [GO:0060452]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of protein kinase C signaling [GO:0090037]; positive regulation of smooth muscle contraction [GO:0045987]; positive regulation of synaptic transmission, GABAergic [GO:0032230]; positive regulation of systemic arterial blood pressure [GO:0003084]; positive regulation of the force of heart contraction by epinephrine-norepinephrine [GO:0001997]; positive regulation of vasoconstriction [GO:0045907]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; response to hormone [GO:0009725]; response to xenobiotic stimulus [GO:0009410]; signal transduction [GO:0007165]; smooth muscle contraction [GO:0006939] GO:0000165; GO:0001985; GO:0001994; GO:0001996; GO:0001997; GO:0003084; GO:0004930; GO:0004937; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005901; GO:0006915; GO:0006939; GO:0007165; GO:0007186; GO:0007200; GO:0007202; GO:0007204; GO:0007267; GO:0007512; GO:0007568; GO:0008285; GO:0009410; GO:0009725; GO:0010259; GO:0010507; GO:0010613; GO:0030018; GO:0030315; GO:0031965; GO:0032230; GO:0035024; GO:0035556; GO:0042734; GO:0043231; GO:0043410; GO:0045211; GO:0045760; GO:0045907; GO:0045987; GO:0046982; GO:0060073; GO:0060402; GO:0060452; GO:0061049; GO:0070374; GO:0071880; GO:0090037; GO:0097195; GO:0098691; GO:0098978; GO:0098982; GO:0099171; GO:0150099; GO:1903997 30363 FUN_036154 326 162 127 218 102 ptg000025l:15788774-15789762 Q8UVX8 2.79e-26 Type II iodothyronine deiodinase (EC 1.21.99.4) (5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase) Neoceratodus forsteri (Australian lungfish) (Ceratodus forsteri) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0016020; GO:0042403; GO:0042446 30364 FUN_036159 472 578 247 183 268 NA NA NA NA NA NA NA 30365 FUN_036158 3493 2848 2107 3119 2768 NA NA NA NA NA NA NA 30366 FUN_044218 0 2 0 0 7 NA NA NA NA NA NA NA 30367 FUN_037825 870 928 278 272 781 NA NA NA NA NA NA NA 30368 FUN_037826 1939 1695 1178 2129 2097 NA NA NA NA NA NA NA 30369 FUN_037827 55 9 43 122 98 NA NA NA NA NA NA NA 30370 FUN_037820 273 347 171 536 389 NA NA NA NA NA NA NA 30371 FUN_037821 990 1119 940 2068 1008 ptg000026l:14050444-14057969 Q91YN5 1.22e-43 UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)] Mus musculus (Mouse) UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0003977; GO:0005654; GO:0005829; GO:0005886; GO:0006047; GO:0006048; GO:0030246; GO:0042802; GO:0052630 30372 FUN_037821 990 1119 940 2068 1008 ptg000026l:14050444-14057969 Q91YN5 4.48e-37 UDP-N-acetylhexosamine pyrophosphorylase [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)] Mus musculus (Mouse) UDP-N-acetylglucosamine biosynthetic process [GO:0006048]; UDP-N-acetylglucosamine metabolic process [GO:0006047] GO:0003977; GO:0005654; GO:0005829; GO:0005886; GO:0006047; GO:0006048; GO:0030246; GO:0042802; GO:0052630 30373 FUN_037822 4565 4135 2445 3871 2006 ptg000026l:14070993-14077987 Q28CH3 2.89e-42 UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0070569 30374 FUN_037822 4565 4135 2445 3871 2006 ptg000026l:14070993-14077987 Q28CH3 2.82e-29 UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 (EC 2.7.7.-) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0070569 30375 FUN_037823 204 98 246 277 280 NA NA NA NA NA NA NA 30376 FUN_026723 74 55 14 78 96 NA NA NA NA NA NA NA 30377 FUN_005305 2466 2534 1582 2216 1325 NA NA NA NA NA NA NA 30378 FUN_005307 232 315 245 290 453 ntLink_8:33879896-33885491 Q07590 3.96e-46 Protein SAV Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) NA GO:0005524; GO:0016887 30379 FUN_005307 232 315 245 290 453 ntLink_8:33879896-33885491 Q07590 3.96e-46 Protein SAV Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) NA GO:0005524; GO:0016887 30380 FUN_005300 0 4 0 0 10 NA NA NA NA NA NA NA 30381 FUN_005301 159 76 29 153 111 NA NA NA NA NA NA NA 30382 FUN_005302 190 184 80 183 157 NA NA NA NA NA NA NA 30383 FUN_005303 781 744 561 757 857 NA NA NA NA NA NA NA 30384 FUN_025709 52 0 171 3 18 NA NA NA NA NA NA NA 30385 FUN_005308 384 256 213 323 246 NA NA NA NA NA NA NA 30386 FUN_005309 31 14 26 3 228 NA NA NA NA NA NA NA 30387 FUN_027223 546 308 347 721 488 ptg000021l:1997400-2004072 Q7RTR2 1.86e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30388 FUN_027220 547 561 470 743 290 NA NA NA NA NA NA NA 30389 FUN_027226 308 248 93 355 35 NA NA NA NA NA NA NA 30390 FUN_027225 0 0 0 11 16 NA NA NA NA NA NA NA 30391 FUN_027224 204 67 94 294 77 NA NA NA NA NA NA NA 30392 FUN_027229 7 0 0 4 3 NA NA NA NA NA NA NA 30393 FUN_027228 770 748 621 1178 258 ptg000021l:2054994-2060164 P59046 7.73e-46 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 30394 FUN_007931 80 94 0 84 19 NA NA NA NA NA NA NA 30395 FUN_002726 44 78 35 62 59 NA NA NA NA NA NA NA 30396 FUN_007933 1 28 12 11 31 NA NA NA NA NA NA NA 30397 FUN_002723 7883 7016 3948 9765 7912 ntLink_8:5727212-5749821 Q9VZX9 1.03e-26 Adenosylhomocysteinase-like 1 (dAhcyL1) (Inactive S-adenosyl-L-homocysteine hydrolase) (S-adenosylhomocysteine hydrolase-like protein 1) Drosophila melanogaster (Fruit fly) one-carbon metabolic process [GO:0006730]; S-adenosylhomocysteine catabolic process [GO:0019510]; S-adenosylmethionine cycle [GO:0033353] GO:0005829; GO:0006730; GO:0019510; GO:0033353 30398 FUN_026724 37 82 36 57 25 NA NA NA NA NA NA NA 30399 FUN_002722 489 470 346 448 400 ntLink_8:5719718-5722228 Q04073 9.12e-118 DNA-binding protein P3A2 Strongylocentrotus purpuratus (Purple sea urchin) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357 30400 FUN_002720 859 921 397 551 477 NA NA NA NA NA NA NA 30401 FUN_008307 1454 754 1348 1334 415 ptg000002l:10141367-10142730 Q3SYV5 1.3e-57 Tetraspanin-33 (Tspan-33) Bos taurus (Bovine) NA GO:0005737; GO:0005886; GO:0005912 30402 FUN_008306 1409 734 543 871 863 NA NA NA NA NA NA NA 30403 FUN_008305 137 153 148 198 128 ptg000002l:10134840-10136034 Q9BQP7 4.87e-38 Mitochondrial genome maintenance exonuclease 1 (EC 3.1.-.-) Homo sapiens (Human) mitochondrial DNA repair [GO:0043504]; mitochondrial DNA replication [GO:0006264]; mitochondrial genome maintenance [GO:0000002] GO:0000002; GO:0005739; GO:0006264; GO:0008297; GO:0043504 30404 FUN_008304 35 91 112 85 104 NA NA NA NA NA NA NA 30405 FUN_008303 2495 4004 1579 2080 2317 NA NA NA NA NA NA NA 30406 FUN_008302 15918 12998 8152 13844 11841 NA NA NA NA NA NA NA 30407 FUN_008301 91 119 65 136 152 ptg000002l:10100058-10101632 Q9H7Z3 8.83e-52 Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) Homo sapiens (Human) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mRNA processing [GO:0006397]; negative regulation of RNA catabolic process [GO:1902369]; positive regulation of RNA export from nucleus [GO:0046833]; RNA splicing [GO:0008380]; RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0000278; GO:0005634; GO:0005654; GO:0005730; GO:0006397; GO:0006974; GO:0008380; GO:0016607; GO:0035194; GO:0046833; GO:0051301; GO:1902369 30408 FUN_008300 112 95 71 93 191 ptg000002l:10097516-10099448 Q80XC6 2.51e-21 Nuclear exosome regulator NRDE2 (Protein NRDE2 homolog) Mus musculus (Mouse) cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; mitotic cell cycle [GO:0000278]; mRNA processing [GO:0006397]; negative regulation of RNA catabolic process [GO:1902369]; positive regulation of RNA export from nucleus [GO:0046833]; RNA splicing [GO:0008380]; RNA-mediated post-transcriptional gene silencing [GO:0035194] GO:0000278; GO:0005634; GO:0005654; GO:0005730; GO:0006397; GO:0006974; GO:0008380; GO:0016607; GO:0035194; GO:0046833; GO:0051301; GO:1902369 30409 FUN_026727 121 95 48 122 103 NA NA NA NA NA NA NA 30410 FUN_008309 37 54 0 5 65 ptg000002l:10157759-10159598 A7S4N4 2.3e-72 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 30411 FUN_008308 29216 39318 15771 20230 16033 NA NA NA NA NA NA NA 30412 FUN_016960 80 26 0 0 16 NA NA NA NA NA NA NA 30413 FUN_016961 24 36 0 51 12 ptg000011l:9442884-9453414 Q96AY4 3.74e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30414 FUN_016961 24 36 0 51 12 ptg000011l:9442884-9453414 Q96AY4 4.54e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30415 FUN_016961 24 36 0 51 12 ptg000011l:9442884-9453414 Q96AY4 5.07e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30416 FUN_016961 24 36 0 51 12 ptg000011l:9442884-9453414 Q96AY4 1.62e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30417 FUN_016961 24 36 0 51 12 ptg000011l:9442884-9453414 Q96AY4 2.85e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30418 FUN_016961 24 36 0 51 12 ptg000011l:9442884-9453414 Q96AY4 3.33e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30419 FUN_016962 321 174 513 478 262 NA NA NA NA NA NA NA 30420 FUN_003468 42 174 0 67 13 NA NA NA NA NA NA NA 30421 FUN_016964 3049 2263 1448 1907 604 NA NA NA NA NA NA NA 30422 FUN_016965 207 60 17 87 120 ptg000011l:9519415-9523219 P12804 2.33e-32 Fibroleukin (Cytotoxic T-lymphocyte-specific protein) (Fibrinogen-like protein 2) (Prothrombinase) Mus musculus (Mouse) cytolysis [GO:0019835]; negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005615; GO:0019835; GO:0043381; GO:0050687; GO:0062023 30423 FUN_016966 65 36 14 190 0 ptg000011l:9535391-9543150 O70165 1.26e-31 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 30424 FUN_016966 65 36 14 190 0 ptg000011l:9535391-9543150 O70165 6.26e-22 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 30425 FUN_016967 34 46 0 102 13 ptg000011l:9553998-9557180 O70165 1.6e-33 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 30426 FUN_016968 653 526 436 643 575 NA NA NA NA NA NA NA 30427 FUN_016969 523 460 531 525 444 NA NA NA NA NA NA NA 30428 FUN_003461 23 315 67 175 80 NA NA NA NA NA NA NA 30429 FUN_003467 690 940 407 1008 409 NA NA NA NA NA NA NA 30430 FUN_003465 0 0 28 0 0 NA NA NA NA NA NA NA 30431 FUN_032702 2250 2212 2883 3834 1446 NA NA NA NA NA NA NA 30432 FUN_032703 2365 2083 1320 930 624 NA NA NA NA NA NA NA 30433 FUN_006457 452 257 347 451 201 NA NA NA NA NA NA NA 30434 FUN_032701 12378 7070 4006 9588 9667 ptg000023l:35053834-35065021 Q09508 9.32e-29 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (FP) Caenorhabditis elegans mitochondrial electron transport, succinate to ubiquinone [GO:0006121]; tricarboxylic acid cycle [GO:0006099] GO:0000104; GO:0005739; GO:0005749; GO:0006099; GO:0006121; GO:0008177; GO:0009055; GO:0050660; GO:0102040 30435 FUN_032706 626 740 367 760 263 ptg000023l:35100954-35102442 Q63ZI0 8.56e-51 Potassium channel subfamily K member 9 Xenopus laevis (African clawed frog) NA GO:0005267; GO:0005886 30436 FUN_006453 1783 573 229 1137 471 ptg000001l:12604506-12649968 P04323 4.19e-57 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 30437 FUN_006452 0 44 0 26 17 ptg000001l:12588570-12597079 Q7RTR2 1.53e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30438 FUN_006452 0 44 0 26 17 ptg000001l:12588570-12597079 Q7RTR2 7.88e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30439 FUN_006452 0 44 0 26 17 ptg000001l:12588570-12597079 Q7RTR2 6.15e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30440 FUN_006452 0 44 0 26 17 ptg000001l:12588570-12597079 Q7RTR2 1.17e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30441 FUN_044079 53 1 67 6 259 ptg000087l:41377-41689 Q6LAF1 2.64e-53 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30442 FUN_032708 216 277 257 419 438 NA NA NA NA NA NA NA 30443 FUN_032709 40349 36685 27090 55856 50345 ptg000023l:35117325-35123590 P20965 2.44e-71 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 30444 FUN_032709 40349 36685 27090 55856 50345 ptg000023l:35117325-35123590 P20965 2.44e-71 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 30445 FUN_032709 40349 36685 27090 55856 50345 ptg000023l:35117325-35123590 P20965 4.22e-28 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 30446 FUN_032709 40349 36685 27090 55856 50345 ptg000023l:35117325-35123590 P20965 6.12e-26 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 30447 FUN_006459 86 0 36 232 51 NA NA NA NA NA NA NA 30448 FUN_006458 206 757 259 271 622 NA NA NA NA NA NA NA 30449 FUN_014358 0 0 2 0 22 NA NA NA NA NA NA NA 30450 FUN_005304 1582 3088 2367 2420 2165 NA NA NA NA NA NA NA 30451 FUN_003799 38 81 34 40 27 ntLink_8:15478047-15481106 P19477 6.65e-40 Fibrinogen-like protein A (FREP-A) Apostichopus parvimensis (Warty sea cucumber) (Stichopus parvimensis) NA NA 30452 FUN_003798 0 0 0 0 10 NA NA NA NA NA NA NA 30453 FUN_004169 84 105 45 112 28 NA NA NA NA NA NA NA 30454 FUN_004165 3618 3912 2023 4063 2855 NA NA NA NA NA NA NA 30455 FUN_004164 852 957 439 1119 816 ntLink_8:19977849-19979004 Q6GQ33 7.87e-66 Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60) Xenopus laevis (African clawed frog) NA GO:0005634; GO:0005737; GO:0018025 30456 FUN_003791 27 11 3 29 40 NA NA NA NA NA NA NA 30457 FUN_003790 158 179 68 77 192 NA NA NA NA NA NA NA 30458 FUN_003793 0 0 7 0 0 NA NA NA NA NA NA NA 30459 FUN_004160 2043 1418 905 1903 1454 ntLink_8:19926098-19956331 Q95SX7 1.86e-27 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30460 FUN_034709 0 20 11 9 0 NA NA NA NA NA NA NA 30461 FUN_030201 498 236 169 313 310 NA NA NA NA NA NA NA 30462 FUN_030200 141 159 43 197 186 NA NA NA NA NA NA NA 30463 FUN_004630 27 0 44 96 147 ntLink_8:25088249-25117435 D8VNT0 5.53e-53 Ryncolin-4 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 30464 FUN_001196 3538 3244 1547 2937 1552 ntLink_6:9678786-9688493 Q64620 1.43e-40 Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) (EC 3.1.3.16) (Protein phosphatase V) (PP-V) Rattus norvegicus (Rat) G1/S transition of mitotic cell cycle [GO:0000082]; innate immune response [GO:0045087]; protein dephosphorylation [GO:0006470] GO:0000082; GO:0004722; GO:0005737; GO:0005739; GO:0005829; GO:0006470; GO:0017018; GO:0045087; GO:0046872 30465 FUN_001108 4159 6477 3002 4196 2239 NA NA NA NA NA NA NA 30466 FUN_001109 1438 1287 937 1424 1381 NA NA NA NA NA NA NA 30467 FUN_001102 2247 1486 851 1695 2523 NA NA NA NA NA NA NA 30468 FUN_023427 51 20 63 90 0 NA NA NA NA NA NA NA 30469 FUN_001101 19 0 0 0 0 NA NA NA NA NA NA NA 30470 FUN_001106 45 0 153 98 96 NA NA NA NA NA NA NA 30471 FUN_001107 1533 1334 477 1416 1393 NA NA NA NA NA NA NA 30472 FUN_001104 0 0 6 1 22 NA NA NA NA NA NA NA 30473 FUN_001105 0 40 915 62 76 NA NA NA NA NA NA NA 30474 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 4.08e-55 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30475 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 1.16e-52 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30476 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 4.09e-48 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30477 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 4.09e-48 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30478 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 7.54e-27 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30479 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 3.48e-26 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30480 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 3.48e-26 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30481 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 2.89e-24 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30482 FUN_011758 10298 6240 5972 11986 12517 ptg000008l:963660-1023560 M0R8U1 5.65e-24 Dynein axonemal heavy chain 5 (Axonemal beta dynein heavy chain 5) (Ciliary dynein heavy chain 5) Rattus norvegicus (Rat) cilium assembly [GO:0060271]; cilium movement [GO:0003341]; determination of left/right symmetry [GO:0007368]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; flagellated sperm motility [GO:0030317]; heart development [GO:0007507]; lateral ventricle development [GO:0021670]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003341; GO:0003351; GO:0003777; GO:0005524; GO:0005576; GO:0005737; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0007368; GO:0007507; GO:0008569; GO:0021670; GO:0030286; GO:0030317; GO:0031514; GO:0036157; GO:0036158; GO:0045505; GO:0051649; GO:0051959; GO:0060271; GO:0097728; GO:0097729 30483 FUN_011759 4 0 38 12 29 NA NA NA NA NA NA NA 30484 FUN_011756 5260 5015 2681 4174 2631 NA NA NA NA NA NA NA 30485 FUN_011755 3078 1872 1414 1895 1757 NA NA NA NA NA NA NA 30486 FUN_011752 161 141 173 110 160 NA NA NA NA NA NA NA 30487 FUN_011753 0 9 0 0 3 NA NA NA NA NA NA NA 30488 FUN_011750 1369 715 473 939 1382 NA NA NA NA NA NA NA 30489 FUN_011751 0 9 3 4 8 NA NA NA NA NA NA NA 30490 FUN_000471 1534 2401 623 1210 548 NA NA NA NA NA NA NA 30491 FUN_000470 1403 1902 486 930 424 NA NA NA NA NA NA NA 30492 FUN_000473 66 55 93 148 117 NA NA NA NA NA NA NA 30493 FUN_000472 41 6 8 22 8 NA NA NA NA NA NA NA 30494 FUN_000475 0 143 136 88 114 NA NA NA NA NA NA NA 30495 FUN_000474 14 0 0 8 37 NA NA NA NA NA NA NA 30496 FUN_000477 717 1140 944 876 470 NA NA NA NA NA NA NA 30497 FUN_000476 292 714 306 477 182 NA NA NA NA NA NA NA 30498 FUN_000478 197 18 21 29 145 ntLink_6:3468351-3474824 O18276 5.31e-24 Gamma-aminobutyric acid receptor subunit beta (GABA(A) receptor subunit beta) Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004890; GO:0005230; GO:0005231; GO:0005254; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1902476; GO:1902711; GO:1904315 30499 FUN_025912 418 645 314 627 223 ptg000020l:1917708-1921014 Q8C790 3.11e-30 Protein FAM221A Mus musculus (Mouse) NA NA 30500 FUN_025912 418 645 314 627 223 ptg000020l:1917708-1921014 Q8C790 4.75e-26 Protein FAM221A Mus musculus (Mouse) NA NA 30501 FUN_029364 17 0 0 12 6 NA NA NA NA NA NA NA 30502 FUN_029365 567 434 422 442 361 NA NA NA NA NA NA NA 30503 FUN_029366 12 0 0 0 10 NA NA NA NA NA NA NA 30504 FUN_029367 0 0 0 0 12 NA NA NA NA NA NA NA 30505 FUN_029360 2476 1885 1477 2068 1747 NA NA NA NA NA NA NA 30506 FUN_029362 1030 193 190 723 402 ptg000023l:1046378-1138049 Q95SX7 6.72e-38 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30507 FUN_029368 447 186 164 244 99 NA NA NA NA NA NA NA 30508 FUN_043498 1590 497 332 3245 564 NA NA NA NA NA NA NA 30509 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 6.01e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30510 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.08e-74 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30511 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.49e-74 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30512 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 6.64e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30513 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.33e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30514 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 6.29e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30515 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 2.04e-55 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30516 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 7.37e-51 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30517 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.48e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30518 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 5.28e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30519 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 3.37e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30520 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 8.22e-48 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30521 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.76e-47 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30522 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.48e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30523 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 2.5e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30524 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.13e-44 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30525 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 1.27e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30526 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 5.81e-22 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30527 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 9.65e-22 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30528 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 4.42e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30529 FUN_043499 2516 795 861 3660 1740 ptg000047l:9330688-9350994 P10079 9.7e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 30530 FUN_005218 3384 4846 2164 2416 1510 NA NA NA NA NA NA NA 30531 FUN_043492 2044 2318 1255 1248 939 NA NA NA NA NA NA NA 30532 FUN_043493 24865 13500 8621 20617 17847 NA NA NA NA NA NA NA 30533 FUN_043490 20 28 0 14 13 NA NA NA NA NA NA NA 30534 FUN_043491 1910 2022 959 3186 2584 NA NA NA NA NA NA NA 30535 FUN_043496 1020 652 595 629 709 NA NA NA NA NA NA NA 30536 FUN_043497 1174 338 436 828 844 NA NA NA NA NA NA NA 30537 FUN_043494 445 116 110 425 232 ptg000047l:9261080-9263335 G5EDE1 3.03e-40 Zinc finger protein GFI1 homolog pag-3 (Pattern of reporter gene expression abnormal protein 3) (Transcription factor pag-3) Caenorhabditis elegans negative regulation of apoptotic process [GO:0043066]; negative regulation of insulin secretion [GO:0046676]; negative regulation of neurotransmitter secretion [GO:0046929]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neuroblast fate specification [GO:0014018]; regulation of backward locomotion [GO:0043058]; regulation of forward locomotion [GO:0043059]; regulation of neuron differentiation [GO:0045664]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0001222; GO:0001227; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0014018; GO:0030424; GO:0043058; GO:0043059; GO:0043066; GO:0043204; GO:0045664; GO:0046676; GO:0046872; GO:0046929 30538 FUN_043495 1511 854 763 1826 1653 NA NA NA NA NA NA NA 30539 FUN_013441 10 17 11 0 38 NA NA NA NA NA NA NA 30540 FUN_013442 3 51 12 72 33 NA NA NA NA NA NA NA 30541 FUN_013443 0 106 45 0 0 NA NA NA NA NA NA NA 30542 FUN_013444 30 247 32 0 14 NA NA NA NA NA NA NA 30543 FUN_013445 21 59 19 9 18 NA NA NA NA NA NA NA 30544 FUN_013447 0 26 17 0 0 NA NA NA NA NA NA NA 30545 FUN_015727 0 48 0 37 3 NA NA NA NA NA NA NA 30546 FUN_015724 3 0 25 2 26 NA NA NA NA NA NA NA 30547 FUN_015723 0 0 0 13 0 NA NA NA NA NA NA NA 30548 FUN_015721 0 0 0 9 0 NA NA NA NA NA NA NA 30549 FUN_015720 14 0 4 17 10 NA NA NA NA NA NA NA 30550 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 7.07e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30551 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 1.93e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30552 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 5.59e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30553 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 9.26e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30554 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 3.1e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30555 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 3.81e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30556 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 4.91e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30557 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 2.47e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30558 FUN_010939 0 303 198 0 396 ptg000007l:4499247-4564677 Q96AY4 3.54e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30559 FUN_010938 127 208 144 136 226 NA NA NA NA NA NA NA 30560 FUN_043720 0 33 0 24 22 NA NA NA NA NA NA NA 30561 FUN_015729 14 0 0 0 0 NA NA NA NA NA NA NA 30562 FUN_043723 11 41 0 102 6 NA NA NA NA NA NA NA 30563 FUN_016191 34 33 39 62 58 NA NA NA NA NA NA NA 30564 FUN_016190 167 610 59 1056 6067 NA NA NA NA NA NA NA 30565 FUN_016193 16 0 0 29 79 NA NA NA NA NA NA NA 30566 FUN_016192 0 0 0 64 46 NA NA NA NA NA NA NA 30567 FUN_016195 133 200 176 243 404 NA NA NA NA NA NA NA 30568 FUN_016194 420 304 187 704 510 ptg000011l:225556-233258 P62289 1.72e-98 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 30569 FUN_016194 420 304 187 704 510 ptg000011l:225556-233258 P62289 1.09e-87 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 30570 FUN_016194 420 304 187 704 510 ptg000011l:225556-233258 P62289 1.31e-83 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 30571 FUN_016194 420 304 187 704 510 ptg000011l:225556-233258 P62289 2.07e-68 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 30572 FUN_016194 420 304 187 704 510 ptg000011l:225556-233258 P62289 1.36e-61 Abnormal spindle-like microcephaly-associated protein homolog Gorilla gorilla gorilla (Western lowland gorilla) cell division [GO:0051301]; establishment of meiotic spindle localization [GO:0051295]; mitotic cell cycle [GO:0000278]; spindle organization [GO:0007051] GO:0000278; GO:0000922; GO:0005516; GO:0005634; GO:0005737; GO:0007051; GO:0051295; GO:0051301 30573 FUN_016197 540 221 318 1123 1185 NA NA NA NA NA NA NA 30574 FUN_016196 170 145 41 142 282 NA NA NA NA NA NA NA 30575 FUN_023043 1613 1251 1620 554 2966 NA NA NA NA NA NA NA 30576 FUN_023042 69 101 70 78 276 NA NA NA NA NA NA NA 30577 FUN_023041 173 176 111 80 201 ptg000017l:2932702-2937914 P40692 3.91e-167 DNA mismatch repair protein Mlh1 (MutL protein homolog 1) Homo sapiens (Human) double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome pairing at meiosis [GO:0007129]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; resolution of meiotic recombination intermediates [GO:0000712]; response to bacterium [GO:0009617]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283] GO:0000289; GO:0000712; GO:0000795; GO:0001673; GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005712; GO:0005715; GO:0006298; GO:0006303; GO:0007060; GO:0007129; GO:0007283; GO:0008630; GO:0009617; GO:0016020; GO:0016321; GO:0016446; GO:0016887; GO:0019899; GO:0032137; GO:0032300; GO:0032389; GO:0043060; GO:0045141; GO:0045190; GO:0045950; GO:0048298; GO:0048304; GO:0048477; GO:0051257; GO:0140664 30578 FUN_023041 173 176 111 80 201 ptg000017l:2932702-2937914 P40692 4.18e-58 DNA mismatch repair protein Mlh1 (MutL protein homolog 1) Homo sapiens (Human) double-strand break repair via nonhomologous end joining [GO:0006303]; female meiosis chromosome segregation [GO:0016321]; homologous chromosome pairing at meiosis [GO:0007129]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; isotype switching [GO:0045190]; male meiosis chromosome segregation [GO:0007060]; meiotic metaphase I plate congression [GO:0043060]; meiotic spindle midzone assembly [GO:0051257]; meiotic telomere clustering [GO:0045141]; mismatch repair [GO:0006298]; negative regulation of mitotic recombination [GO:0045950]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; oogenesis [GO:0048477]; positive regulation of isotype switching to IgA isotypes [GO:0048298]; positive regulation of isotype switching to IgG isotypes [GO:0048304]; resolution of meiotic recombination intermediates [GO:0000712]; response to bacterium [GO:0009617]; somatic hypermutation of immunoglobulin genes [GO:0016446]; spermatogenesis [GO:0007283] GO:0000289; GO:0000712; GO:0000795; GO:0001673; GO:0003682; GO:0005524; GO:0005634; GO:0005654; GO:0005694; GO:0005712; GO:0005715; GO:0006298; GO:0006303; GO:0007060; GO:0007129; GO:0007283; GO:0008630; GO:0009617; GO:0016020; GO:0016321; GO:0016446; GO:0016887; GO:0019899; GO:0032137; GO:0032300; GO:0032389; GO:0043060; GO:0045141; GO:0045190; GO:0045950; GO:0048298; GO:0048304; GO:0048477; GO:0051257; GO:0140664 30579 FUN_023040 8696 5065 5221 10986 8645 NA NA NA NA NA NA NA 30580 FUN_023047 338 268 237 234 277 NA NA NA NA NA NA NA 30581 FUN_023046 365 204 135 214 215 NA NA NA NA NA NA NA 30582 FUN_023045 900 1603 742 978 1378 NA NA NA NA NA NA NA 30583 FUN_023044 8367 6848 4108 7014 5605 NA NA NA NA NA NA NA 30584 FUN_028095 983 1318 488 682 688 ptg000021l:15777164-15779478 B0W939 5.54e-26 Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20) Culex quinquefasciatus (Southern house mosquito) (Culex pungens) mRNA cis splicing, via spliceosome [GO:0045292]; RNA-mediated gene silencing [GO:0031047] GO:0000339; GO:0005634; GO:0005846; GO:0031047; GO:0045292 30585 FUN_028094 1302 891 634 857 673 NA NA NA NA NA NA NA 30586 FUN_028097 330 222 323 106 309 ptg000021l:15784693-15786514 Q91Z92 1.11e-46 Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0005794; GO:0005797; GO:0006024; GO:0006486; GO:0008194; GO:0015012; GO:0016757; GO:0030166; GO:0030206; GO:0032580; GO:0035250; GO:0047220 30587 FUN_028097 330 222 323 106 309 ptg000021l:15784693-15786514 Q91Z92 6.12e-27 Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6) Mus musculus (Mouse) chondroitin sulfate biosynthetic process [GO:0030206]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein glycosylation [GO:0006486]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0005794; GO:0005797; GO:0006024; GO:0006486; GO:0008194; GO:0015012; GO:0016757; GO:0030166; GO:0030206; GO:0032580; GO:0035250; GO:0047220 30588 FUN_028096 683 677 504 623 754 NA NA NA NA NA NA NA 30589 FUN_036838 0 0 0 0 17 NA NA NA NA NA NA NA 30590 FUN_028093 1234 877 712 1295 1003 NA NA NA NA NA NA NA 30591 FUN_028092 2336 1102 914 1718 1264 ptg000021l:15716822-15747090 O15438 2.44e-46 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0009925; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0043225; GO:0055085; GO:0071714; GO:0071716; GO:0140359; GO:0150104 30592 FUN_028092 2336 1102 914 1718 1264 ptg000021l:15716822-15747090 O15438 3.97e-23 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0009925; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0043225; GO:0055085; GO:0071714; GO:0071716; GO:0140359; GO:0150104 30593 FUN_028092 2336 1102 914 1718 1264 ptg000021l:15716822-15747090 O15438 5.08e-22 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0009925; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0043225; GO:0055085; GO:0071714; GO:0071716; GO:0140359; GO:0150104 30594 FUN_036834 0 0 0 0 15 NA NA NA NA NA NA NA 30595 FUN_036837 11 0 0 0 10 ptg000026l:2522574-2526657 Q9NBX4 6.28e-35 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 30596 FUN_028099 376 214 173 312 272 NA NA NA NA NA NA NA 30597 FUN_028098 1319 516 386 714 587 NA NA NA NA NA NA NA 30598 FUN_036832 0 15 0 3 0 NA NA NA NA NA NA NA 30599 FUN_036833 270 234 280 310 209 NA NA NA NA NA NA NA 30600 FUN_008841 0 551 784 189 239 NA NA NA NA NA NA NA 30601 FUN_008842 2 4 82 237 140 NA NA NA NA NA NA NA 30602 FUN_041388 0 24 4 0 29 NA NA NA NA NA NA NA 30603 FUN_041389 128 22 27 77 80 ptg000035l:3081510-3082428 Q32PP9 4.95e-50 Transcription factor Sox-14 Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; hypothalamus development [GO:0021854]; regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0009653; GO:0021854; GO:0030154 30604 FUN_028549 2419 909 1443 3447 2340 NA NA NA NA NA NA NA 30605 FUN_028548 2658 2414 922 2704 2635 NA NA NA NA NA NA NA 30606 FUN_028547 2374 1819 615 720 790 NA NA NA NA NA NA NA 30607 FUN_041386 2595 1528 1906 3572 3164 ptg000035l:2986632-3046064 Q5JSL3 7.48e-28 Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2) Homo sapiens (Human) B cell homeostasis [GO:0001782]; marginal zone B cell differentiation [GO:0002315]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of GTPase activity [GO:0043547]; small GTPase mediated signal transduction [GO:0007264] GO:0001782; GO:0002315; GO:0005085; GO:0005829; GO:0007264; GO:0031267; GO:0043547; GO:0051491 30608 FUN_023504 234 208 119 218 71 NA NA NA NA NA NA NA 30609 FUN_014806 1353 871 455 1080 623 ptg000009l:3256671-3258861 Q2YDR3 5.72e-78 Inositol monophosphatase 3 (IMP 3) (IMPase 3) (EC 3.1.3.25) (3'(2'), 5'-bisphosphate nucleotidase 2) (Inositol monophosphatase domain-containing protein 1) (Inositol-1(or 4)-monophosphatase 3) (Myo-inositol monophosphatase A3) Danio rerio (Zebrafish) (Brachydanio rerio) inositol biosynthetic process [GO:0006021]; inositol phosphate dephosphorylation [GO:0046855]; phosphatidylinositol phosphate biosynthetic process [GO:0046854] GO:0006021; GO:0008254; GO:0008934; GO:0012505; GO:0016020; GO:0046854; GO:0046855; GO:0046872; GO:0052832; GO:0052833 30610 FUN_041656 8438 10404 6428 20181 14723 NA NA NA NA NA NA NA 30611 FUN_041657 379 273 315 302 544 NA NA NA NA NA NA NA 30612 FUN_041654 6069 4664 2209 4428 3055 NA NA NA NA NA NA NA 30613 FUN_041655 0 0 0 9 13 NA NA NA NA NA NA NA 30614 FUN_041652 16 24 0 0 0 NA NA NA NA NA NA NA 30615 FUN_041653 257 161 151 184 195 NA NA NA NA NA NA NA 30616 FUN_041650 3794 2756 1824 3747 2651 NA NA NA NA NA NA NA 30617 FUN_041651 2547 1297 1149 2242 1096 NA NA NA NA NA NA NA 30618 FUN_039417 15 0 6 16 4 NA NA NA NA NA NA NA 30619 FUN_039895 3133 3994 2383 3577 1738 NA NA NA NA NA NA NA 30620 FUN_041658 181 155 234 217 222 NA NA NA NA NA NA NA 30621 FUN_041659 1342 1131 355 1094 568 ptg000035l:6303842-6307198 P39963 1.52e-40 G2/mitotic-specific cyclin-B3 Gallus gallus (Chicken) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0005634; GO:0005737; GO:0005813; GO:0016538; GO:0044772; GO:0051301 30622 FUN_041659 1342 1131 355 1094 568 ptg000035l:6303842-6307198 P39963 1.52e-40 G2/mitotic-specific cyclin-B3 Gallus gallus (Chicken) cell division [GO:0051301]; mitotic cell cycle phase transition [GO:0044772]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079] GO:0000079; GO:0000307; GO:0005634; GO:0005737; GO:0005813; GO:0016538; GO:0044772; GO:0051301 30623 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 1.42e-46 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30624 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 5.98e-46 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30625 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 5.98e-46 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30626 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 5.98e-46 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30627 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 1.34e-38 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30628 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 3.21e-31 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30629 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 4.37e-30 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30630 FUN_022798 261 338 576 1195 1699 ptg000017l:62692-98394 Q86WI1 2.64e-29 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 30631 FUN_022799 0 0 11 14 9 NA NA NA NA NA NA NA 30632 FUN_022498 671 324 674 1507 1585 NA NA NA NA NA NA NA 30633 FUN_022790 0 34 0 0 131 NA NA NA NA NA NA NA 30634 FUN_022791 54 166 66 141 384 NA NA NA NA NA NA NA 30635 FUN_022792 3 4 11 5 91 NA NA NA NA NA NA NA 30636 FUN_022793 14 51 18 30 109 NA NA NA NA NA NA NA 30637 FUN_022794 38 22 0 46 46 NA NA NA NA NA NA NA 30638 FUN_022795 4 0 0 0 22 NA NA NA NA NA NA NA 30639 FUN_022796 69 34 36 78 77 NA NA NA NA NA NA NA 30640 FUN_022797 5933 5251 3059 5399 5536 ptg000017l:45577-59994 Q29090 2.09e-37 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) Sus scrofa (Pig) protein dephosphorylation [GO:0006470] GO:0000159; GO:0005829; GO:0006470; GO:0019888 30641 FUN_022797 5933 5251 3059 5399 5536 ptg000017l:45577-59994 Q29090 7.62e-35 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) Sus scrofa (Pig) protein dephosphorylation [GO:0006470] GO:0000159; GO:0005829; GO:0006470; GO:0019888 30642 FUN_022797 5933 5251 3059 5399 5536 ptg000017l:45577-59994 Q29090 1.26e-32 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) Sus scrofa (Pig) protein dephosphorylation [GO:0006470] GO:0000159; GO:0005829; GO:0006470; GO:0019888 30643 FUN_022797 5933 5251 3059 5399 5536 ptg000017l:45577-59994 Q29090 2.77e-21 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha) Sus scrofa (Pig) protein dephosphorylation [GO:0006470] GO:0000159; GO:0005829; GO:0006470; GO:0019888 30644 FUN_039416 260 38 55 295 133 ptg000029c:1610750-1611830 Q7RTR2 4.32e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30645 FUN_039416 260 38 55 295 133 ptg000029c:1610750-1611830 Q7RTR2 1.83e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30646 FUN_039416 260 38 55 295 133 ptg000029c:1610750-1611830 Q7RTR2 2.73e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30647 FUN_039416 260 38 55 295 133 ptg000029c:1610750-1611830 Q7RTR2 7.84e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30648 FUN_039416 260 38 55 295 133 ptg000029c:1610750-1611830 Q7RTR2 3.19e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30649 FUN_039416 260 38 55 295 133 ptg000029c:1610750-1611830 Q7RTR2 2.03e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30650 FUN_022493 241 18 229 132 91 NA NA NA NA NA NA NA 30651 FUN_014139 113 26 36 15 43 NA NA NA NA NA NA NA 30652 FUN_014134 19 0 21 0 0 NA NA NA NA NA NA NA 30653 FUN_014137 0 0 0 0 15 NA NA NA NA NA NA NA 30654 FUN_014131 525 39 1 2 490 NA NA NA NA NA NA NA 30655 FUN_014130 3721 4 0 5 12 NA NA NA NA NA NA NA 30656 FUN_014133 20 0 0 0 0 NA NA NA NA NA NA NA 30657 FUN_042871 2306 1519 1878 1570 928 NA NA NA NA NA NA NA 30658 FUN_022497 22 0 0 30 109 NA NA NA NA NA NA NA 30659 FUN_015515 583 286 68 239 374 NA NA NA NA NA NA NA 30660 FUN_025072 0 0 24 0 33 NA NA NA NA NA NA NA 30661 FUN_025073 0 0 7 0 0 NA NA NA NA NA NA NA 30662 FUN_039899 0 0 3 8 6 NA NA NA NA NA NA NA 30663 FUN_015517 14 0 0 0 0 NA NA NA NA NA NA NA 30664 FUN_042870 47 820 41 69 355 NA NA NA NA NA NA NA 30665 FUN_024303 7 45 9 25 13 ptg000018l:4564882-4569621 Q5DU56 2.59e-39 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30666 FUN_024302 0 20 31 58 0 NA NA NA NA NA NA NA 30667 FUN_024305 10 106 67 111 36 NA NA NA NA NA NA NA 30668 FUN_024304 0 71 38 38 71 NA NA NA NA NA NA NA 30669 FUN_024307 13 62 157 102 71 ptg000018l:4615152-4734242 P59046 4.88e-46 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 30670 FUN_024307 13 62 157 102 71 ptg000018l:4615152-4734242 P59046 3.29e-31 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 30671 FUN_024306 40 39 8 21 4 ptg000018l:4597292-4600546 Q8K3Z0 1.37e-35 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 30672 FUN_024309 11 117 72 54 81 NA NA NA NA NA NA NA 30673 FUN_024308 43 53 38 47 21 ptg000018l:4738574-4743380 Q8R4B8 2.04e-41 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) (Cold autoinflammatory syndrome 1 protein homolog) (Cryopyrin) (Mast cell maturation-associated-inducible protein 1) (PYRIN-containing APAF1-like protein 1) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; osmosensory signaling pathway [GO:0007231]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; pyroptosis [GO:0070269]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002221; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0005815; GO:0005829; GO:0006919; GO:0006954; GO:0007231; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070269; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 30674 FUN_012676 5549 4110 2888 5714 6584 ptg000008l:11193401-11228845 Q12873 7.83e-24 Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH) Homo sapiens (Human) centrosome cycle [GO:0007098]; chromatin remodeling [GO:0006338]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of cell fate specification [GO:0042659]; regulation of DNA-templated transcription [GO:0006355]; regulation of stem cell differentiation [GO:2000736]; spindle organization [GO:0007051] GO:0000122; GO:0000785; GO:0000976; GO:0003677; GO:0003682; GO:0003723; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005813; GO:0006338; GO:0006355; GO:0007051; GO:0007098; GO:0008270; GO:0016575; GO:0016581; GO:0016605; GO:0016887; GO:0034451; GO:0042393; GO:0042659; GO:0045892; GO:0045893; GO:0140658; GO:2000736 30675 FUN_012151 83 79 33 38 74 ptg000008l:5684865-5693229 Q91W96 3.27e-95 Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4) Mus musculus (Mouse) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell cycle [GO:0007049]; cell division [GO:0051301]; protein K11-linked ubiquitination [GO:0070979]; regulation of mitotic metaphase/anaphase transition [GO:0030071] GO:0005634; GO:0005680; GO:0007049; GO:0019903; GO:0030071; GO:0031145; GO:0034399; GO:0051301; GO:0070979 30676 FUN_012150 928 1265 539 846 1055 NA NA NA NA NA NA NA 30677 FUN_015262 1176 1096 644 1409 1295 NA NA NA NA NA NA NA 30678 FUN_015263 18169 17397 11935 8103 8521 NA NA NA NA NA NA NA 30679 FUN_015260 139 9 78 0 29 NA NA NA NA NA NA NA 30680 FUN_015261 1134 2367 32 1536 1273 ptg000009l:8025368-8029974 Q9MYM7 1.1e-28 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 30681 FUN_015266 57 47 2 71 15 NA NA NA NA NA NA NA 30682 FUN_015267 121 69 99 336 259 NA NA NA NA NA NA NA 30683 FUN_015264 1061 1185 555 602 637 NA NA NA NA NA NA NA 30684 FUN_015265 1245 497 1416 1862 5048 ptg000009l:8058801-8071329 A5PKF5 5.1e-22 THAP domain-containing protein 11 Bos taurus (Bovine) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0003677; GO:0005654; GO:0005737; GO:0006357; GO:0008270 30685 FUN_017303 233 0 67 21 41 NA NA NA NA NA NA NA 30686 FUN_015268 1661 773 1709 3088 4709 NA NA NA NA NA NA NA 30687 FUN_015269 249 145 211 181 363 NA NA NA NA NA NA NA 30688 FUN_017302 20 0 46 89 0 NA NA NA NA NA NA NA 30689 FUN_012157 51 354 104 20 96 NA NA NA NA NA NA NA 30690 FUN_012156 195 115 144 267 167 NA NA NA NA NA NA NA 30691 FUN_038421 55 106 27 77 65 ptg000027l:7023909-7028459 Q8BJQ2 8.72e-26 Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment] Mus musculus (Mouse) DNA repair [GO:0006281]; monoubiquitinated protein deubiquitination [GO:0035520]; protein deubiquitination [GO:0016579]; regulation of DNA repair [GO:0006282]; response to UV [GO:0009411]; skeletal system development [GO:0001501]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0001501; GO:0004197; GO:0004843; GO:0005634; GO:0005654; GO:0005829; GO:0006281; GO:0006282; GO:0006511; GO:0008233; GO:0009411; GO:0016579; GO:0035520 30692 FUN_038420 1088 1047 349 427 400 NA NA NA NA NA NA NA 30693 FUN_038423 585 589 539 975 810 NA NA NA NA NA NA NA 30694 FUN_038422 12106 10048 7727 8224 4608 NA NA NA NA NA NA NA 30695 FUN_038425 23 0 0 3 32 NA NA NA NA NA NA NA 30696 FUN_038424 887 794 717 685 1077 NA NA NA NA NA NA NA 30697 FUN_038427 174 95 81 97 104 NA NA NA NA NA NA NA 30698 FUN_038426 5035 3849 2048 5972 3150 NA NA NA NA NA NA NA 30699 FUN_038429 426 400 160 293 364 NA NA NA NA NA NA NA 30700 FUN_038428 35 122 27 54 65 NA NA NA NA NA NA NA 30701 FUN_023825 5 27 35 55 55 NA NA NA NA NA NA NA 30702 FUN_023827 0 0 9 0 6 NA NA NA NA NA NA NA 30703 FUN_031704 303 302 681 987 701 NA NA NA NA NA NA NA 30704 FUN_031703 160 96 458 1045 366 NA NA NA NA NA NA NA 30705 FUN_031702 65 0 67 69 123 ptg000023l:24502424-24522845 Q6IVV8 2.86e-34 Polycystin-2 (Curly up) (Cup) (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Danio rerio (Zebrafish) (Brachydanio rerio) atrioventricular valve development [GO:0003171]; calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; cellular response to oscillatory fluid shear stress [GO:0097704]; cilium assembly [GO:0060271]; detection of mechanical stimulus [GO:0050982]; determination of heart left/right asymmetry [GO:0061371]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; embryonic heart tube morphogenesis [GO:0003143]; heart development [GO:0007507]; heart jogging [GO:0003146]; heart looping [GO:0001947]; hematopoietic progenitor cell differentiation [GO:0002244]; inorganic cation transmembrane transport [GO:0098662]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; lymphangiogenesis [GO:0001946]; Notch signaling pathway [GO:0007219]; positive regulation of sequestering of calcium ion [GO:0051284]; potassium ion transmembrane transport [GO:0071805]; pronephros development [GO:0048793]; pronephros morphogenesis [GO:0072114]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; protein-containing complex assembly [GO:0065003]; proximal convoluted tubule development [GO:0072019]; regulation of cardiac muscle contraction by calcium ion signaling [GO:0010882]; regulation of collagen biosynthetic process [GO:0032965]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; ventriculo bulbo valve development [GO:0003173]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001946; GO:0001947; GO:0002244; GO:0003143; GO:0003146; GO:0003171; GO:0003173; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005856; GO:0005886; GO:0005929; GO:0007219; GO:0007368; GO:0007507; GO:0009953; GO:0010882; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0016324; GO:0016328; GO:0030017; GO:0030659; GO:0032965; GO:0033017; GO:0034703; GO:0034765; GO:0042383; GO:0048793; GO:0050982; GO:0051209; GO:0051262; GO:0051284; GO:0051290; GO:0051371; GO:0060271; GO:0060972; GO:0061371; GO:0065003; GO:0070121; GO:0070588; GO:0071277; GO:0071805; GO:0072019; GO:0072114; GO:0097704; GO:0098662; GO:0198738 30706 FUN_031701 1524 2407 953 1658 1947 NA NA NA NA NA NA NA 30707 FUN_023822 24 0 0 0 0 NA NA NA NA NA NA NA 30708 FUN_023829 9 0 28 0 123 NA NA NA NA NA NA NA 30709 FUN_023828 0 0 12 0 45 ptg000017l:11900226-11900989 P84239 2.54e-90 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 30710 FUN_031709 698 792 610 1076 948 NA NA NA NA NA NA NA 30711 FUN_031708 64699 104776 25077 35814 31234 ptg000023l:24619772-24626047 P26642 5.36e-36 Elongation factor 1-gamma-A (EF-1-gamma-A) (eEF-1B gamma-A) (p47) Xenopus laevis (African clawed frog) NA GO:0003746 30712 FUN_003469 119 142 73 203 50 NA NA NA NA NA NA NA 30713 FUN_016963 6714 6455 3991 6901 3967 NA NA NA NA NA NA NA 30714 FUN_035329 7516 2354 3738 1781 2161 NA NA NA NA NA NA NA 30715 FUN_038792 155 107 153 185 274 NA NA NA NA NA NA NA 30716 FUN_042878 884 946 586 755 1412 NA NA NA NA NA NA NA 30717 FUN_003462 176 2920 436 1488 436 NA NA NA NA NA NA NA 30718 FUN_014451 1015 955 722 1080 1007 NA NA NA NA NA NA NA 30719 FUN_002946 12 6 6 5 14 NA NA NA NA NA NA NA 30720 FUN_016504 763 603 393 672 504 ptg000011l:4097643-4168849 Q9P7S7 3.92e-30 Nucleolar protein 58 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) rRNA processing [GO:0006364] GO:0005634; GO:0005730; GO:0006364; GO:0030515; GO:0031428; GO:0032040 30721 FUN_016504 763 603 393 672 504 ptg000011l:4097643-4168849 Q9P7S7 1.18e-29 Nucleolar protein 58 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) rRNA processing [GO:0006364] GO:0005634; GO:0005730; GO:0006364; GO:0030515; GO:0031428; GO:0032040 30722 FUN_037899 2723 517 379 781 1804 NA NA NA NA NA NA NA 30723 FUN_037898 868 928 515 1304 1032 NA NA NA NA NA NA NA 30724 FUN_027025 623 1072 512 360 463 NA NA NA NA NA NA NA 30725 FUN_027024 40 9 5 26 29 NA NA NA NA NA NA NA 30726 FUN_027027 0 0 10 0 19 NA NA NA NA NA NA NA 30727 FUN_044026 112 392 783 391 229 NA NA NA NA NA NA NA 30728 FUN_002943 0 7 0 2 0 NA NA NA NA NA NA NA 30729 FUN_030891 0 0 8 0 0 NA NA NA NA NA NA NA 30730 FUN_017613 4 0 0 0 9 NA NA NA NA NA NA NA 30731 FUN_037897 34 29 46 24 127 NA NA NA NA NA NA NA 30732 FUN_017614 0 0 0 0 7 NA NA NA NA NA NA NA 30733 FUN_017249 3 2 17 22 66 NA NA NA NA NA NA NA 30734 FUN_017243 14 35 46 31 141 NA NA NA NA NA NA NA 30735 FUN_017247 3 0 0 0 42 NA NA NA NA NA NA NA 30736 FUN_006455 1419 701 696 932 1163 NA NA NA NA NA NA NA 30737 FUN_006454 104 0 20 0 20 NA NA NA NA NA NA NA 30738 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.96e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30739 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.81e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30740 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 3.56e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30741 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 9.04e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30742 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 2e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30743 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.13e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30744 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.13e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30745 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 6.31e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30746 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 5.37e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30747 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 5.37e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30748 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 2.56e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30749 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 2.56e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30750 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 4.11e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30751 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.7e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30752 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 5.1e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30753 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 2.69e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30754 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 9.22e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30755 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.04e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30756 FUN_006456 695 174 31 946 234 ptg000001l:12684072-12692637 Q7RTR2 1.83e-35 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30757 FUN_006451 0 0 0 75 2 NA NA NA NA NA NA NA 30758 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 7.65e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30759 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 4.38e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30760 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 1.51e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30761 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 1.64e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30762 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 4.23e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30763 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 2.18e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30764 FUN_006450 42 227 225 470 142 ptg000001l:12559817-12569719 Q7RTR2 5.32e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30765 FUN_004369 157 107 6 108 57 NA NA NA NA NA NA NA 30766 FUN_004368 349 129 44 328 141 NA NA NA NA NA NA NA 30767 FUN_004365 6648 8521 4067 6809 6484 NA NA NA NA NA NA NA 30768 FUN_004364 17 0 0 0 12 NA NA NA NA NA NA NA 30769 FUN_004367 934 967 494 706 481 NA NA NA NA NA NA NA 30770 FUN_004366 807 619 393 899 558 NA NA NA NA NA NA NA 30771 FUN_004361 1422 751 551 659 540 NA NA NA NA NA NA NA 30772 FUN_004360 1165 1153 693 876 610 NA NA NA NA NA NA NA 30773 FUN_004363 227 293 201 486 670 NA NA NA NA NA NA NA 30774 FUN_004362 4941 3926 2216 3654 2533 NA NA NA NA NA NA NA 30775 FUN_044027 76 544 890 249 262 NA NA NA NA NA NA NA 30776 FUN_018113 0 0 0 0 15 NA NA NA NA NA NA NA 30777 FUN_018110 10 0 7 74 35 NA NA NA NA NA NA NA 30778 FUN_018115 1 0 2 0 10 NA NA NA NA NA NA NA 30779 FUN_026048 274 105 964 1323 351 ptg000020l:4094490-4097798 Q7RTR2 9.52e-27 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30780 FUN_026049 40 49 17 137 73 ptg000020l:4101842-4103903 Q8NFZ3 1.14e-85 Neuroligin-4, Y-linked (Neuroligin Y) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; learning [GO:0007612]; modulation of chemical synaptic transmission [GO:0050804]; neuron cell-cell adhesion [GO:0007158]; postsynaptic membrane assembly [GO:0097104]; presynapse assembly [GO:0099054]; presynaptic membrane assembly [GO:0097105]; social behavior [GO:0035176]; synaptic vesicle endocytosis [GO:0048488]; vocalization behavior [GO:0071625] GO:0005886; GO:0007158; GO:0007268; GO:0007612; GO:0009986; GO:0016020; GO:0035176; GO:0038023; GO:0042043; GO:0045202; GO:0048488; GO:0050804; GO:0050839; GO:0071625; GO:0097104; GO:0097105; GO:0097110; GO:0098793; GO:0098839; GO:0098983; GO:0098985; GO:0099054; GO:0099634 30781 FUN_026040 22 0 0 0 4 NA NA NA NA NA NA NA 30782 FUN_026041 3343 406 658 140 924 ptg000020l:4012343-4017823 C6FG12 1.9e-26 Protein NLRC5 Ictalurus punctatus (Channel catfish) (Silurus punctatus) innate immune response [GO:0045087] GO:0005524; GO:0005737; GO:0045087 30783 FUN_026042 17 277 0 0 16 ptg000020l:4019557-4027729 Q86WI3 3.25e-27 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 30784 FUN_026043 206 42 13 0 35 ptg000020l:4031573-4036404 Q86WI3 5.5e-26 Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) Homo sapiens (Human) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type I interferon-mediated signaling pathway [GO:0060340]; positive regulation of type II interferon-mediated signaling pathway [GO:0060335]; regulation of kinase activity [GO:0043549]; response to bacterium [GO:0009617] GO:0000978; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0009617; GO:0032088; GO:0035556; GO:0043549; GO:0045087; GO:0045345; GO:0045944; GO:0051607; GO:0060335; GO:0060339; GO:0060340 30785 FUN_026044 458 255 70 291 720 ptg000020l:4049281-4052791 Q7RTR2 1.85e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30786 FUN_026045 38 4 35 0 12 NA NA NA NA NA NA NA 30787 FUN_026046 2716 625 355 493 679 NA NA NA NA NA NA NA 30788 FUN_026047 408 104 838 4306 585 ptg000020l:4084327-4089672 Q8K3Z0 3.43e-27 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 30789 FUN_025539 855 514 547 556 817 NA NA NA NA NA NA NA 30790 FUN_025538 520 520 390 503 605 NA NA NA NA NA NA NA 30791 FUN_025531 381 141 192 374 434 NA NA NA NA NA NA NA 30792 FUN_025530 535 462 289 522 339 NA NA NA NA NA NA NA 30793 FUN_025532 584 236 585 960 286 ptg000019l:3935484-3984252 Q4W1X2 4.11e-108 NA NA NA NA 30794 FUN_025534 525 159 50 288 388 NA NA NA NA NA NA NA 30795 FUN_025537 261 1880 703 2771 169 NA NA NA NA NA NA NA 30796 FUN_025536 335 82 97 1154 789 NA NA NA NA NA NA NA 30797 FUN_003795 0 11 0 88 17 NA NA NA NA NA NA NA 30798 FUN_003797 34 91 0 51 0 ntLink_8:15458889-15462439 O70165 3.71e-40 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 30799 FUN_003796 252 305 335 287 93 NA NA NA NA NA NA NA 30800 FUN_004163 1551 1052 776 1522 1244 NA NA NA NA NA NA NA 30801 FUN_004162 2963 4154 1147 1319 822 NA NA NA NA NA NA NA 30802 FUN_004161 60 36 36 20 38 NA NA NA NA NA NA NA 30803 FUN_003792 2220 1721 720741 1875 993 NA NA NA NA NA NA NA 30804 FUN_013559 57127 45468 39719 35705 22958 NA NA NA NA NA NA NA 30805 FUN_007184 1353 840 1969 2045 5988 NA NA NA NA NA NA NA 30806 FUN_007185 7 6 61 34 104 NA NA NA NA NA NA NA 30807 FUN_007186 189 449 372 442 1155 NA NA NA NA NA NA NA 30808 FUN_007187 13 10 37 4 280 NA NA NA NA NA NA NA 30809 FUN_007180 694 255 397 472 614 ptg000001l:21316055-21329950 P21328 1.68e-26 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 30810 FUN_007181 5416 3203 2297 4505 4170 ptg000001l:21331158-21346622 Q6N069 4.17e-26 N-alpha-acetyltransferase 16, NatA auxiliary subunit (NMDA receptor-regulated 1-like protein) (NARG1-like protein) Homo sapiens (Human) N-terminal peptidyl-methionine acetylation [GO:0017196]; N-terminal protein amino acid acetylation [GO:0006474]; negative regulation of apoptotic process [GO:0043066]; positive regulation of DNA-templated transcription [GO:0045893]; protein stabilization [GO:0050821] GO:0005634; GO:0005667; GO:0005737; GO:0005829; GO:0006474; GO:0017196; GO:0031415; GO:0043022; GO:0043066; GO:0045893; GO:0050821; GO:0070062 30811 FUN_007182 1000 787 523 774 850 ptg000001l:21346963-21353626 Q6DD32 1.7e-25 E3 ubiquitin ligase Rnf121 (EC 2.3.2.27) (RING finger protein 121) Xenopus laevis (African clawed frog) NA GO:0016020; GO:0046872 30812 FUN_007183 2868 716 432 1464 1586 ptg000001l:21357362-21367791 O16025 1.05e-33 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 30813 FUN_007183 2868 716 432 1464 1586 ptg000001l:21357362-21367791 O16025 2.18e-30 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 30814 FUN_007183 2868 716 432 1464 1586 ptg000001l:21357362-21367791 O16025 4.02e-27 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 30815 FUN_007183 2868 716 432 1464 1586 ptg000001l:21357362-21367791 O16025 2.72e-24 Allene oxide synthase-lipoxygenase protein [Includes: Allene oxide synthase (AOS) (EC 4.2.1.-) (Hydroperoxidehydrase); Arachidonate 8-lipoxygenase (EC 1.13.11.40)] Plexaura homomalla (Black sea rod) arachidonic acid metabolic process [GO:0019369]; fatty acid biosynthetic process [GO:0006633]; lipid oxidation [GO:0034440]; oxylipin biosynthetic process [GO:0031408] GO:0005506; GO:0005737; GO:0006633; GO:0009978; GO:0016020; GO:0019369; GO:0020037; GO:0031408; GO:0034440; GO:0047677 30816 FUN_005973 2338 269 855 2384 859 ptg000001l:6319489-6323498 C3ZQF9 1.79e-29 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 30817 FUN_005970 1267 533 779 1129 560 ptg000001l:6296007-6299197 A7RPT4 3.34e-32 NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase) Nematostella vectensis (Starlet sea anemone) NA GO:0000166; GO:0046872; GO:0052856; GO:0052857 30818 FUN_005970 1267 533 779 1129 560 ptg000001l:6296007-6299197 A7RPT4 5.51e-29 NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase) Nematostella vectensis (Starlet sea anemone) NA GO:0000166; GO:0046872; GO:0052856; GO:0052857 30819 FUN_005970 1267 533 779 1129 560 ptg000001l:6296007-6299197 A7RPT4 4.37e-24 NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase) Nematostella vectensis (Starlet sea anemone) NA GO:0000166; GO:0046872; GO:0052856; GO:0052857 30820 FUN_007188 214 546 261 518 1402 NA NA NA NA NA NA NA 30821 FUN_005976 117 52 68 151 19 NA NA NA NA NA NA NA 30822 FUN_005974 156 329 63 104 32 ptg000001l:6350253-6351593 P25931 1.99e-25 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 30823 FUN_034982 0 0 0 0 11 NA NA NA NA NA NA NA 30824 FUN_034983 1158 1346 406 387 891 ptg000025l:2380580-2389847 Q9P0L9 1.76e-39 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) (Polycystin-2L1) (Polycystin-L) (Polycystin-L1) Homo sapiens (Human) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0009986; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0033040; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071468; GO:0071805; GO:0097730; GO:0098662 30825 FUN_034980 55 181 74 79 71 NA NA NA NA NA NA NA 30826 FUN_034981 64 82 9 23 51 NA NA NA NA NA NA NA 30827 FUN_034986 2564 1435 1200 1880 1200 NA NA NA NA NA NA NA 30828 FUN_034987 0 0 0 15 13 NA NA NA NA NA NA NA 30829 FUN_034984 1312 2285 600 954 937 NA NA NA NA NA NA NA 30830 FUN_034985 810 526 546 513 693 ptg000025l:2408432-2410549 B5X4H8 1.95e-79 Riboflavin transporter 2 (RFT2) Salmo salar (Atlantic salmon) NA GO:0005886; GO:0032217 30831 FUN_034988 0 49 24 117 43 ptg000025l:2456930-2550904 P14381 2.24e-54 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 30832 FUN_034989 124 0 19 121 69 NA NA NA NA NA NA NA 30833 FUN_024797 1504 246 605 1609 1173 ptg000018l:11172840-11183904 Q6NUT3 6.2e-34 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 30834 FUN_035589 29 0 22 49 96 NA NA NA NA NA NA NA 30835 FUN_035588 0 69 56 437 157 NA NA NA NA NA NA NA 30836 FUN_035581 111 65 53 58 74 NA NA NA NA NA NA NA 30837 FUN_035580 0 87 0 105 0 NA NA NA NA NA NA NA 30838 FUN_035582 95 59 0 139 65 NA NA NA NA NA NA NA 30839 FUN_035585 17 22 35 18 21 NA NA NA NA NA NA NA 30840 FUN_035584 24 188 40 64 42 NA NA NA NA NA NA NA 30841 FUN_035587 63 74 403 98 177 NA NA NA NA NA NA NA 30842 FUN_035586 0 20 0 0 0 NA NA NA NA NA NA NA 30843 FUN_042037 83 38 21 45 36 NA NA NA NA NA NA NA 30844 FUN_042036 1182 654 585 1077 750 ptg000035l:9987814-10007933 O00410 4.26e-47 Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] GO:0003723; GO:0005095; GO:0005634; GO:0005643; GO:0005730; GO:0005737; GO:0006606; GO:0006607; GO:0006610; GO:0008139; GO:0016020; GO:0031267; GO:0042307; GO:0045736; GO:0061608; GO:0071230 30845 FUN_042036 1182 654 585 1077 750 ptg000035l:9987814-10007933 O00410 2.45e-28 Importin-5 (Imp5) (Importin subunit beta-3) (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5) Homo sapiens (Human) cellular response to amino acid stimulus [GO:0071230]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; NLS-bearing protein import into nucleus [GO:0006607]; positive regulation of protein import into nucleus [GO:0042307]; protein import into nucleus [GO:0006606]; ribosomal protein import into nucleus [GO:0006610] GO:0003723; GO:0005095; GO:0005634; GO:0005643; GO:0005730; GO:0005737; GO:0006606; GO:0006607; GO:0006610; GO:0008139; GO:0016020; GO:0031267; GO:0042307; GO:0045736; GO:0061608; GO:0071230 30846 FUN_042035 2919 2071 1605 1544 1635 NA NA NA NA NA NA NA 30847 FUN_006276 7581 4641 2876 5086 4042 NA NA NA NA NA NA NA 30848 FUN_006271 12 36 0 4 107 NA NA NA NA NA NA NA 30849 FUN_006272 10538 26 172 12116 1872 NA NA NA NA NA NA NA 30850 FUN_006279 171 196 89 15 119 NA NA NA NA NA NA NA 30851 FUN_006278 1668 1614 898 1785 1010 NA NA NA NA NA NA NA 30852 FUN_042039 91 62 0 52 55 NA NA NA NA NA NA NA 30853 FUN_042038 80 39 38 16 40 NA NA NA NA NA NA NA 30854 FUN_037983 275 144 118 292 255 ptg000027l:1161521-1163591 Q8BTK5 1.82e-56 SET and MYND domain-containing protein 4 (EC 2.1.1.-) Mus musculus (Mouse) heart development [GO:0007507]; methylation [GO:0032259] GO:0005634; GO:0005737; GO:0007507; GO:0008168; GO:0032259; GO:0042826; GO:0046872 30855 FUN_037982 1854 1775 1131 1571 1613 NA NA NA NA NA NA NA 30856 FUN_037981 2851 4029 992 1891 1402 ptg000027l:1143130-1149604 Q8BQZ5 1.24e-32 Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K) Mus musculus (Mouse) pre-mRNA cleavage required for polyadenylation [GO:0098789] GO:0003723; GO:0005654; GO:0005847; GO:0008270; GO:0043231; GO:0098789; GO:1990837 30857 FUN_037980 361 322 110 297 89 NA NA NA NA NA NA NA 30858 FUN_037987 239 328 88 313 96 ptg000027l:1187796-1191107 A0A2B4RNI3 1.04e-28 NA NA NA NA 30859 FUN_037986 755 553 639 789 852 ptg000027l:1176911-1186193 Q8BX80 5.41e-44 Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96) Mus musculus (Mouse) protein deglycosylation [GO:0006517] GO:0004553; GO:0005829; GO:0006517; GO:0033925 30860 FUN_037986 755 553 639 789 852 ptg000027l:1176911-1186193 Q8BX80 5.41e-44 Cytosolic endo-beta-N-acetylglucosaminidase (ENGase) (EC 3.2.1.96) Mus musculus (Mouse) protein deglycosylation [GO:0006517] GO:0004553; GO:0005829; GO:0006517; GO:0033925 30861 FUN_037985 1320 1154 696 1162 1138 ptg000027l:1174179-1175883 Q9QZB9 1.55e-27 Dynactin subunit 5 (Dynactin subunit p25) Mus musculus (Mouse) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281] GO:0000776; GO:0003281; GO:0005654; GO:0005737; GO:0005813; GO:0005869; GO:0031965; GO:0035904; GO:0060976 30862 FUN_037985 1320 1154 696 1162 1138 ptg000027l:1174179-1175883 Q9QZB9 1.55e-27 Dynactin subunit 5 (Dynactin subunit p25) Mus musculus (Mouse) aorta development [GO:0035904]; coronary vasculature development [GO:0060976]; ventricular septum development [GO:0003281] GO:0000776; GO:0003281; GO:0005654; GO:0005737; GO:0005813; GO:0005869; GO:0031965; GO:0035904; GO:0060976 30863 FUN_037984 3261 1703 901 1547 1404 NA NA NA NA NA NA NA 30864 FUN_037989 11 0 5 0 0 NA NA NA NA NA NA NA 30865 FUN_037988 201 172 144 95 94 NA NA NA NA NA NA NA 30866 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 6.13e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30867 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 1.66e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30868 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 4.03e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30869 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 8.52e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30870 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 9.31e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30871 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 2.47e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30872 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 1.06e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30873 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 1.46e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30874 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 5.84e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30875 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 7.51e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30876 FUN_035633 414 2735 340 1892 122 ptg000025l:10099240-10157398 Q7RTR2 3.22e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 30877 FUN_035632 834 652 308 488 496 NA NA NA NA NA NA NA 30878 FUN_035631 14 0 0 8 6 NA NA NA NA NA NA NA 30879 FUN_035637 14 0 0 0 0 NA NA NA NA NA NA NA 30880 FUN_035636 1804 870 721 855 1500 NA NA NA NA NA NA NA 30881 FUN_035635 12167 12850 6488 12656 7617 ptg000025l:10166679-10167189 Q8QGW7 5.61e-26 Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog (LPS-induced TNF-alpha factor homolog) (Small integral membrane protein of lysosome/late endosome) Gallus gallus (Chicken) cytokine production [GO:0001816]; sexual reproduction [GO:0019953] GO:0000139; GO:0001816; GO:0003677; GO:0005125; GO:0005634; GO:0005765; GO:0008270; GO:0009898; GO:0019953; GO:0098559; GO:0098560; GO:0098574 30882 FUN_026189 0 0 0 5 10 NA NA NA NA NA NA NA 30883 FUN_035639 632 461 358 498 238 NA NA NA NA NA NA NA 30884 FUN_035638 965 439 439 340 424 NA NA NA NA NA NA NA 30885 FUN_026188 278 195 459 457 387 NA NA NA NA NA NA NA 30886 FUN_003980 63 40 17 88 98 NA NA NA NA NA NA NA 30887 FUN_003982 901 351 418 442 391 NA NA NA NA NA NA NA 30888 FUN_003983 297 165 521 318 1314 NA NA NA NA NA NA NA 30889 FUN_003984 11 0 6 7 102 NA NA NA NA NA NA NA 30890 FUN_003985 75 0 38 114 100 NA NA NA NA NA NA NA 30891 FUN_003986 295 40 226 637 374 NA NA NA NA NA NA NA 30892 FUN_003987 0 0 0 100 33 NA NA NA NA NA NA NA 30893 FUN_003988 0 0 0 5 9 ntLink_8:17774905-17780014 P51049 7.71e-24 Melatonin receptor type 1B-B (Mel-1B-R-B) (Mel1b receptor B) (Melatonin receptor Mel1b Z2.6-4) (zMel1b-1) Danio rerio (Zebrafish) (Brachydanio rerio) G protein-coupled receptor signaling pathway [GO:0007186]; rhythmic process [GO:0048511] GO:0004930; GO:0005886; GO:0007186; GO:0008502; GO:0048511 30894 FUN_003989 13 37 39 44 65 ntLink_8:17781045-17788403 Q96AY4 1.43e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30895 FUN_014656 1108 1176 731 926 1036 ptg000009l:1869697-1870693 Q6GQD5 6.02e-56 E3 ubiquitin-protein ligase rnf146 (EC 2.3.2.27) (RING finger protein 146) (RING-type E3 ubiquitin transferase rnf146) Xenopus laevis (African clawed frog) positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; ubiquitin-dependent protein catabolic process [GO:0006511]; Wnt signaling pathway [GO:0016055] GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0008270; GO:0016055; GO:0051865; GO:0061630; GO:0070936; GO:0072572; GO:0090263 30896 FUN_037677 49 38 52 21 109 NA NA NA NA NA NA NA 30897 FUN_014657 2093 1841 1137 1761 1818 NA NA NA NA NA NA NA 30898 FUN_014650 1235 857 431 658 920 NA NA NA NA NA NA NA 30899 FUN_037679 95 0 151 89 207 NA NA NA NA NA NA NA 30900 FUN_037678 275 61 261 138 141 NA NA NA NA NA NA NA 30901 FUN_014651 1252 1302 704 956 664 NA NA NA NA NA NA NA 30902 FUN_032009 0 17 17 6 6 NA NA NA NA NA NA NA 30903 FUN_023351 8464 10795 6741 6050 3239 NA NA NA NA NA NA NA 30904 FUN_032005 58 39 20 3755 1762 NA NA NA NA NA NA NA 30905 FUN_032004 16388 20701 7317 15052 11893 NA NA NA NA NA NA NA 30906 FUN_032007 385 83 85 413 409 NA NA NA NA NA NA NA 30907 FUN_023350 2567 3124 1960 1705 1161 NA NA NA NA NA NA NA 30908 FUN_032001 365 266 226 245 290 NA NA NA NA NA NA NA 30909 FUN_032000 16 20 0 44 29 NA NA NA NA NA NA NA 30910 FUN_032003 7479 8369 5973 5190 3146 NA NA NA NA NA NA NA 30911 FUN_001728 705 363 570 492 541 NA NA NA NA NA NA NA 30912 FUN_001729 9 50 32 62 36 NA NA NA NA NA NA NA 30913 FUN_039266 4814 16909 11788 8158 9017 ptg000028l:25950-27465 P12394 1.08e-132 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] GO:0004508; GO:0005506; GO:0006694; GO:0008202; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 30914 FUN_001722 54 51 34 63 25 NA NA NA NA NA NA NA 30915 FUN_001723 1024 547 623 592 138 NA NA NA NA NA NA NA 30916 FUN_001720 0 26 0 0 0 ntLink_6:15334615-15336046 P79218 5.6e-42 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 30917 FUN_001721 0 0 0 0 13 NA NA NA NA NA NA NA 30918 FUN_001726 77 94 63 51 53 NA NA NA NA NA NA NA 30919 FUN_001727 220 264 133 295 188 ntLink_6:15381643-15392692 P22770 5.65e-65 Neuronal acetylcholine receptor subunit alpha-7 Gallus gallus (Chicken) calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; membrane depolarization [GO:0051899]; negative regulation of tumor necrosis factor production [GO:0032720]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of MAPK cascade [GO:0043410]; regulation of nitric oxide metabolic process [GO:0080164]; response to hypoxia [GO:0001666]; response to nicotine [GO:0035094]; signal transduction [GO:0007165] GO:0001540; GO:0001666; GO:0005737; GO:0005886; GO:0005892; GO:0006816; GO:0006874; GO:0007165; GO:0008284; GO:0015464; GO:0015643; GO:0017081; GO:0022848; GO:0030424; GO:0030425; GO:0032720; GO:0035094; GO:0042166; GO:0042803; GO:0043204; GO:0043410; GO:0045211; GO:0045766; GO:0050890; GO:0051899; GO:0080164 30920 FUN_001724 44 0 18 35 14 NA NA NA NA NA NA NA 30921 FUN_001725 252 321 145 199 189 ntLink_6:15363959-15367464 Q15825 1.42e-28 Neuronal acetylcholine receptor subunit alpha-6 Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of dopamine secretion [GO:0014059]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0014059; GO:0015464; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0042734; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:0098691; GO:0099171; GO:1904315 30922 FUN_043816 0 0 0 12 39 NA NA NA NA NA NA NA 30923 FUN_043810 72 7 193 14 193 ptg000049l:1637907-1643569 P14381 2.85e-116 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 30924 FUN_007601 15 13 14 33 35 NA NA NA NA NA NA NA 30925 FUN_007600 0 0 6 24 5 NA NA NA NA NA NA NA 30926 FUN_007607 2524 1570 895 2552 2042 NA NA NA NA NA NA NA 30927 FUN_007606 106 126 76 204 93 ptg000002l:2305326-2328935 P0CT40 3.15e-25 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 30928 FUN_007606 106 126 76 204 93 ptg000002l:2305326-2328935 P0CT40 3.15e-25 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 30929 FUN_007605 622 649 240 516 417 ptg000002l:2293171-2295373 Q5JTD7 1.98e-32 Leucine-rich repeat-containing protein 73 Homo sapiens (Human) NA NA 30930 FUN_007604 3791 3155 2781 3581 2429 NA NA NA NA NA NA NA 30931 FUN_007609 0 0 0 0 6 NA NA NA NA NA NA NA 30932 FUN_041580 633 522 349 465 706 NA NA NA NA NA NA NA 30933 FUN_008534 860 431 236 431 811 NA NA NA NA NA NA NA 30934 FUN_008535 2166 1553 1194 2482 1455 NA NA NA NA NA NA NA 30935 FUN_008536 1890 1381 1004 1836 1363 NA NA NA NA NA NA NA 30936 FUN_008537 5983 3460 2806 4038 4313 NA NA NA NA NA NA NA 30937 FUN_008530 1676 1594 1070 809 1341 NA NA NA NA NA NA NA 30938 FUN_008531 621 320 189 608 475 NA NA NA NA NA NA NA 30939 FUN_008532 32930 13138 14607 18137 3489 NA NA NA NA NA NA NA 30940 FUN_008533 7961 5851 5514 9026 8388 NA NA NA NA NA NA NA 30941 FUN_008538 1200 1045 642 660 441 NA NA NA NA NA NA NA 30942 FUN_008539 814 780 444 484 450 NA NA NA NA NA NA NA 30943 FUN_005115 1251 879 556 923 702 ntLink_8:31232699-31242525 Q9UI40 4.44e-78 Sodium/potassium/calcium exchanger 2 (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) Homo sapiens (Human) calcium ion import [GO:0070509]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; establishment of localization in cell [GO:0051649]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; learning [GO:0007612]; long-term synaptic depression [GO:0060292]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; neuron cellular homeostasis [GO:0070050]; phototransduction [GO:0007602]; potassium ion transmembrane transport [GO:0071805]; sodium ion transmembrane transport [GO:0035725] GO:0001917; GO:0005262; GO:0005886; GO:0006811; GO:0006874; GO:0007602; GO:0007612; GO:0007613; GO:0008273; GO:0015293; GO:0034220; GO:0035725; GO:0036368; GO:0051649; GO:0060291; GO:0060292; GO:0070050; GO:0070509; GO:0070588; GO:0071486; GO:0071805; GO:0098703 30944 FUN_005114 1320 730 695 1058 1239 NA NA NA NA NA NA NA 30945 FUN_005117 3143 1714 1397 2850 1657 NA NA NA NA NA NA NA 30946 FUN_005116 1238 626 628 1492 168 NA NA NA NA NA NA NA 30947 FUN_005111 949 375 181 671 553 NA NA NA NA NA NA NA 30948 FUN_041712 246 214 114 350 206 NA NA NA NA NA NA NA 30949 FUN_005113 6627 4384 2847 4490 3976 ntLink_8:31185925-31205479 P20825 1.92e-73 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 30950 FUN_005112 13394 19645 10305 13383 10029 NA NA NA NA NA NA NA 30951 FUN_005119 2265 1109 1232 2485 2637 NA NA NA NA NA NA NA 30952 FUN_005118 3708 2448 1667 2644 2025 ntLink_8:31263466-31265439 Q9VQ93 6.85e-71 Golgi phosphoprotein 3 homolog sauron (Protein rotini) Drosophila melanogaster (Fruit fly) actomyosin contractile ring assembly [GO:0000915]; cleavage furrow formation [GO:0036089]; Golgi organization [GO:0007030]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle budding [GO:0048194]; male meiosis cytokinesis [GO:0007112]; meiosis I cytokinesis [GO:0007110]; meiosis II cytokinesis [GO:0007111]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly [GO:0090307]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spindle assembly [GO:0051225]; spindle assembly involved in male meiosis [GO:0007053]; viral entry into host cell [GO:0046718] GO:0000139; GO:0000281; GO:0000301; GO:0000915; GO:0005794; GO:0005802; GO:0005829; GO:0006890; GO:0007030; GO:0007053; GO:0007110; GO:0007111; GO:0007112; GO:0010314; GO:0031267; GO:0031410; GO:0031985; GO:0032154; GO:0032266; GO:0036089; GO:0043001; GO:0046718; GO:0048194; GO:0051225; GO:0070273; GO:0070300; GO:0090307 30953 FUN_005118 3708 2448 1667 2644 2025 ntLink_8:31263466-31265439 Q9VQ93 2.19e-38 Golgi phosphoprotein 3 homolog sauron (Protein rotini) Drosophila melanogaster (Fruit fly) actomyosin contractile ring assembly [GO:0000915]; cleavage furrow formation [GO:0036089]; Golgi organization [GO:0007030]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi vesicle budding [GO:0048194]; male meiosis cytokinesis [GO:0007112]; meiosis I cytokinesis [GO:0007110]; meiosis II cytokinesis [GO:0007111]; mitotic cytokinesis [GO:0000281]; mitotic spindle assembly [GO:0090307]; retrograde transport, vesicle recycling within Golgi [GO:0000301]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; spindle assembly [GO:0051225]; spindle assembly involved in male meiosis [GO:0007053]; viral entry into host cell [GO:0046718] GO:0000139; GO:0000281; GO:0000301; GO:0000915; GO:0005794; GO:0005802; GO:0005829; GO:0006890; GO:0007030; GO:0007053; GO:0007110; GO:0007111; GO:0007112; GO:0010314; GO:0031267; GO:0031410; GO:0031985; GO:0032154; GO:0032266; GO:0036089; GO:0043001; GO:0046718; GO:0048194; GO:0051225; GO:0070273; GO:0070300; GO:0090307 30954 FUN_041719 993 757 310 583 408 NA NA NA NA NA NA NA 30955 FUN_041718 2637 1414 1205 1599 1701 NA NA NA NA NA NA NA 30956 FUN_033352 117 51 40 92 213 NA NA NA NA NA NA NA 30957 FUN_033350 274 266 180 133 262 ptg000023l:42203268-42206382 Q96AY4 4.16e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30958 FUN_033350 274 266 180 133 262 ptg000023l:42203268-42206382 Q96AY4 9.41e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30959 FUN_033350 274 266 180 133 262 ptg000023l:42203268-42206382 Q96AY4 1.33e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30960 FUN_033350 274 266 180 133 262 ptg000023l:42203268-42206382 Q96AY4 4.57e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30961 FUN_033350 274 266 180 133 262 ptg000023l:42203268-42206382 Q96AY4 6.51e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30962 FUN_033350 274 266 180 133 262 ptg000023l:42203268-42206382 Q96AY4 2.23e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30963 FUN_033351 0 0 0 0 6 NA NA NA NA NA NA NA 30964 FUN_043405 44 16 2 8 22 NA NA NA NA NA NA NA 30965 FUN_032913 0 32 0 33 26 NA NA NA NA NA NA NA 30966 FUN_032912 327 516 248 544 333 ptg000023l:37560073-37569193 Q96AY4 1.44e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30967 FUN_032912 327 516 248 544 333 ptg000023l:37560073-37569193 Q96AY4 1.08e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30968 FUN_032912 327 516 248 544 333 ptg000023l:37560073-37569193 Q96AY4 2.07e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30969 FUN_032912 327 516 248 544 333 ptg000023l:37560073-37569193 Q96AY4 6.77e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30970 FUN_032912 327 516 248 544 333 ptg000023l:37560073-37569193 Q96AY4 4.96e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30971 FUN_032912 327 516 248 544 333 ptg000023l:37560073-37569193 Q96AY4 8.01e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30972 FUN_032911 0 5 2 20 2 NA NA NA NA NA NA NA 30973 FUN_032910 21 0 17 18 83 NA NA NA NA NA NA NA 30974 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30975 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30976 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30977 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 4.46e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30978 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 7.31e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30979 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 1.17e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30980 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 3.13e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30981 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 6.04e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30982 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 4.03e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30983 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 1.22e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30984 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 8.28e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30985 FUN_032917 565 227 139 172 58 ptg000023l:37630009-37634383 Q96AY4 9.18e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30986 FUN_032916 0 9 0 0 0 NA NA NA NA NA NA NA 30987 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30988 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 2.04e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30989 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 8.37e-175 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30990 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 4.39e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30991 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 1.27e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30992 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 5.03e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30993 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 5.36e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30994 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 6.52e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30995 FUN_032915 540 187 242 92 75 ptg000023l:37600868-37605256 Q96AY4 2.06e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 30996 FUN_029099 1994 1505 1745 3282 4380 NA NA NA NA NA NA NA 30997 FUN_029096 164 76 158 259 298 NA NA NA NA NA NA NA 30998 FUN_029097 1094 1482 953 1587 886 NA NA NA NA NA NA NA 30999 FUN_029094 852 392 435 525 495 NA NA NA NA NA NA NA 31000 FUN_029093 1451 1467 873 2513 1337 ptg000022l:8178687-8192677 Q63ZT8 1.35e-48 Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; NADPH regeneration [GO:0006740]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730] GO:0001755; GO:0005829; GO:0006730; GO:0006740; GO:0007369; GO:0007507; GO:0009058; GO:0009258; GO:0016155; GO:0016620; GO:0016742; GO:0016787; GO:0048703; GO:0048885 31001 FUN_029093 1451 1467 873 2513 1337 ptg000022l:8178687-8192677 Q63ZT8 6.76e-24 Cytosolic 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (FDH) (EC 1.5.1.6) (Aldehyde dehydrogenase family 1 member L1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) 10-formyltetrahydrofolate catabolic process [GO:0009258]; biosynthetic process [GO:0009058]; embryonic viscerocranium morphogenesis [GO:0048703]; gastrulation [GO:0007369]; heart development [GO:0007507]; NADPH regeneration [GO:0006740]; neural crest cell migration [GO:0001755]; neuromast deposition [GO:0048885]; one-carbon metabolic process [GO:0006730] GO:0001755; GO:0005829; GO:0006730; GO:0006740; GO:0007369; GO:0007507; GO:0009058; GO:0009258; GO:0016155; GO:0016620; GO:0016742; GO:0016787; GO:0048703; GO:0048885 31002 FUN_029090 2 4 9 0 33 NA NA NA NA NA NA NA 31003 FUN_029091 3884 2434 2188 4941 3369 NA NA NA NA NA NA NA 31004 FUN_014615 15465 13079 5935 7366 5627 ptg000009l:1572626-1575269 Q15370 4.92e-29 Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2) Homo sapiens (Human) positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein ubiquitination [GO:0016567]; protein-containing complex assembly [GO:0065003]; transcription elongation by RNA polymerase II promoter [GO:0006368]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0001222; GO:0005654; GO:0005829; GO:0006367; GO:0006368; GO:0016567; GO:0030891; GO:0031462; GO:0031466; GO:0031625; GO:0032436; GO:0065003; GO:0070449 31005 FUN_014616 2038 1229 727 1437 1650 NA NA NA NA NA NA NA 31006 FUN_003619 0 0 9 0 0 ntLink_8:13566869-13574872 O70165 6.64e-38 Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin) Mus musculus (Mouse) cell surface pattern recognition receptor signaling pathway [GO:0002752]; complement activation, lectin pathway [GO:0001867]; G protein-coupled receptor signaling pathway [GO:0007186]; positive regulation of interleukin-8 production [GO:0032757] GO:0001867; GO:0002752; GO:0003823; GO:0005102; GO:0005581; GO:0005615; GO:0007186; GO:0030246; GO:0031232; GO:0032757; GO:0038187; GO:0046872; GO:0062023; GO:0097367 31007 FUN_004648 12 0 19 9 10 ntLink_8:25347207-25348238 Q06725 7.17e-22 Nuclear receptor subfamily 2 group F member 1-A (COUP transcription factor 1-A) (COUP-TFalpha-A) (zCOUP-TFI) (Seven-up related 44) (Svp[44]) (zSvp[44]) (Steroid receptor homolog SVP 44) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; atrial cardiac muscle cell differentiation [GO:0055011]; cardiac atrium morphogenesis [GO:0003209]; cardiac muscle tissue development [GO:0048738]; cell differentiation [GO:0030154]; endothelial cell proliferation [GO:0001935]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; vasculature development [GO:0001944] GO:0000122; GO:0000978; GO:0001935; GO:0001944; GO:0003209; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0045944; GO:0048738; GO:0048856; GO:0055011 31008 FUN_004649 4 0 48 0 120 NA NA NA NA NA NA NA 31009 FUN_004642 1294 485 441 701 1057 NA NA NA NA NA NA NA 31010 FUN_004643 261 50 95 146 357 ntLink_8:25315812-25317174 C9JN71 2.31e-122 Zinc finger protein 878 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31011 FUN_004643 261 50 95 146 357 ntLink_8:25315812-25317174 C9JN71 2.33e-111 Zinc finger protein 878 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31012 FUN_004643 261 50 95 146 357 ntLink_8:25315812-25317174 C9JN71 3.36e-106 Zinc finger protein 878 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31013 FUN_004643 261 50 95 146 357 ntLink_8:25315812-25317174 C9JN71 1.33e-96 Zinc finger protein 878 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31014 FUN_004643 261 50 95 146 357 ntLink_8:25315812-25317174 C9JN71 3.75e-80 Zinc finger protein 878 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000977; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31015 FUN_004640 139 70 53 331 190 ntLink_8:25287620-25296248 Q9NBX4 2.25e-29 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 31016 FUN_004641 8655 10604 9397 7131 3999 NA NA NA NA NA NA NA 31017 FUN_004646 16 38 0 80 12 ntLink_8:25340652-25343358 P48442 3.96e-97 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 31018 FUN_003615 0 0 18 0 0 NA NA NA NA NA NA NA 31019 FUN_004644 57 5 3 20 26 NA NA NA NA NA NA NA 31020 FUN_004645 12 0 23 0 75 NA NA NA NA NA NA NA 31021 FUN_040045 0 0 0 34 21 NA NA NA NA NA NA NA 31022 FUN_040047 27 30 47 93 44 NA NA NA NA NA NA NA 31023 FUN_029080 1425 523 942 1034 552 ptg000022l:7971801-7974345 Q769K2 2.15e-80 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (N-acyl phosphatidylethanolamine phospholipase D) (NAPE-PLD) (NAPE-hydrolyzing phospholipase D) (EC 3.1.4.54) Rattus norvegicus (Rat) aging [GO:0007568]; host-mediated regulation of intestinal microbiota composition [GO:0048874]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; negative regulation of eating behavior [GO:1903999]; phospholipid catabolic process [GO:0009395]; phospholipid metabolic process [GO:0006644]; positive regulation of brown fat cell differentiation [GO:0090336]; positive regulation of inflammatory response [GO:0050729]; response to isolation stress [GO:0035900]; temperature homeostasis [GO:0001659] GO:0000139; GO:0001659; GO:0004620; GO:0005635; GO:0005654; GO:0005737; GO:0005769; GO:0005794; GO:0006644; GO:0007568; GO:0008270; GO:0009395; GO:0031901; GO:0032052; GO:0035900; GO:0042802; GO:0043227; GO:0048874; GO:0050729; GO:0070290; GO:0070291; GO:0070292; GO:0090336; GO:0102200; GO:1903999 31024 FUN_040048 369 843 638 781 633 NA NA NA NA NA NA NA 31025 FUN_041313 1257 1594 799 1543 750 NA NA NA NA NA NA NA 31026 FUN_041311 4851 2697 2585 3420 2763 NA NA NA NA NA NA NA 31027 FUN_029083 470 133 281 323 463 NA NA NA NA NA NA NA 31028 FUN_028328 112 484 340 30 311 NA NA NA NA NA NA NA 31029 FUN_028327 595 325 286 233 396 NA NA NA NA NA NA NA 31030 FUN_028324 91 621 215 221 100 ptg000021l:18363527-18400394 Q95SX7 8.58e-33 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 31031 FUN_028322 205 0 0 136 80 NA NA NA NA NA NA NA 31032 FUN_028321 138 0 0 512 272 NA NA NA NA NA NA NA 31033 FUN_028320 36 71 68 92 100 NA NA NA NA NA NA NA 31034 FUN_002414 0 90 44 47 94 NA NA NA NA NA NA NA 31035 FUN_041761 1761 901 1048 1322 1443 NA NA NA NA NA NA NA 31036 FUN_002569 45 11 79 31 65 NA NA NA NA NA NA NA 31037 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 1.7e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31038 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 2.46e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31039 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 2.97e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31040 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 2.61e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31041 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 4.59e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31042 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 4.04e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31043 FUN_009558 89 72 32 145 132 ptg000004l:8505675-8510082 Q96AY4 9.01e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31044 FUN_002561 6 323 127 797 1053 NA NA NA NA NA NA NA 31045 FUN_002560 187 155 284 1048 1490 NA NA NA NA NA NA NA 31046 FUN_002562 13 2 11 12 14 NA NA NA NA NA NA NA 31047 FUN_002565 31 63 37 268 356 NA NA NA NA NA NA NA 31048 FUN_002567 347 460 532 462 175 NA NA NA NA NA NA NA 31049 FUN_002566 70 69 26 66 27 NA NA NA NA NA NA NA 31050 FUN_011094 7 0 0 4 0 NA NA NA NA NA NA NA 31051 FUN_010971 168 12 0 0 41 NA NA NA NA NA NA NA 31052 FUN_012216 7236 5733 2896 5474 3687 NA NA NA NA NA NA NA 31053 FUN_012217 4741 1522 1456 1888 1140 NA NA NA NA NA NA NA 31054 FUN_012214 0 0 0 12 14 NA NA NA NA NA NA NA 31055 FUN_012215 444 32 343 212 140 ptg000008l:6447678-6453600 A2RU49 1.43e-25 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Homo sapiens (Human) lysine catabolic process [GO:0006554]; phosphorylation [GO:0016310] GO:0005759; GO:0006554; GO:0016310; GO:0019202; GO:0047992 31056 FUN_012212 112 450 119 578 80 NA NA NA NA NA NA NA 31057 FUN_012213 2009 2546 963 1852 1839 NA NA NA NA NA NA NA 31058 FUN_012211 548 197 314 436 260 NA NA NA NA NA NA NA 31059 FUN_029992 0 0 3 0 10 NA NA NA NA NA NA NA 31060 FUN_007711 0 0 0 13 30 NA NA NA NA NA NA NA 31061 FUN_025981 0 29 201 0 76 NA NA NA NA NA NA NA 31062 FUN_007712 15 85 27 13 29 NA NA NA NA NA NA NA 31063 FUN_043029 420 221 140 162 208 NA NA NA NA NA NA NA 31064 FUN_043025 437 534 300 352 227 NA NA NA NA NA NA NA 31065 FUN_043024 0 0 11 13 0 NA NA NA NA NA NA NA 31066 FUN_043023 2 17 13 36 4 NA NA NA NA NA NA NA 31067 FUN_010973 40 0 0 34 54 NA NA NA NA NA NA NA 31068 FUN_007717 0 19 0 0 11 NA NA NA NA NA NA NA 31069 FUN_009556 38 0 0 70 0 NA NA NA NA NA NA NA 31070 FUN_016979 2314 1372 833 1527 1063 NA NA NA NA NA NA NA 31071 FUN_014687 0 0 0 0 23 NA NA NA NA NA NA NA 31072 FUN_014686 1631 1243 874 1671 1791 NA NA NA NA NA NA NA 31073 FUN_014685 22 0 25 45 133 NA NA NA NA NA NA NA 31074 FUN_014684 15 0 5 60 43 NA NA NA NA NA NA NA 31075 FUN_014683 527 473 389 5104 350 NA NA NA NA NA NA NA 31076 FUN_014682 906 412 320 852 921 NA NA NA NA NA NA NA 31077 FUN_014681 477 283 182 327 239 NA NA NA NA NA NA NA 31078 FUN_014680 2610 2197 1362 2201 1756 NA NA NA NA NA NA NA 31079 FUN_014689 64 10 48 79 55 NA NA NA NA NA NA NA 31080 FUN_014688 58 29 96 120 93 NA NA NA NA NA NA NA 31081 FUN_022914 16237 10905 7400 20421 15996 NA NA NA NA NA NA NA 31082 FUN_009618 0 0 0 0 14 NA NA NA NA NA NA NA 31083 FUN_009619 290 132 116 50 97 NA NA NA NA NA NA NA 31084 FUN_009617 1 0 22 77 65 ptg000004l:9437506-9444354 Q96AY4 1.2e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31085 FUN_009617 1 0 22 77 65 ptg000004l:9437506-9444354 Q96AY4 8.52e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31086 FUN_009617 1 0 22 77 65 ptg000004l:9437506-9444354 Q96AY4 6.19e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31087 FUN_009617 1 0 22 77 65 ptg000004l:9437506-9444354 Q96AY4 3.08e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31088 FUN_009617 1 0 22 77 65 ptg000004l:9437506-9444354 Q96AY4 1.71e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31089 FUN_009617 1 0 22 77 65 ptg000004l:9437506-9444354 Q96AY4 3.17e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31090 FUN_009614 546 12 150 4 152 ptg000004l:9376356-9381829 Q96AY4 2.81e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31091 FUN_009614 546 12 150 4 152 ptg000004l:9376356-9381829 Q96AY4 4.73e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31092 FUN_009614 546 12 150 4 152 ptg000004l:9376356-9381829 Q96AY4 2.28e-104 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31093 FUN_009614 546 12 150 4 152 ptg000004l:9376356-9381829 Q96AY4 3.79e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31094 FUN_009614 546 12 150 4 152 ptg000004l:9376356-9381829 Q96AY4 2.72e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31095 FUN_009615 486 185 0 173 320 NA NA NA NA NA NA NA 31096 FUN_009612 82 84 55 101 66 ptg000004l:9328153-9329079 Q80XJ3 1.03e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31097 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 5.15e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31098 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 8.59e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31099 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 1.69e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31100 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 2.18e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31101 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 1.04e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31102 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 4.27e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31103 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 2.97e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31104 FUN_009613 9 7 29 27 0 ptg000004l:9329340-9331998 Q96AY4 1.79e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31105 FUN_009610 107 58 37 82 69 NA NA NA NA NA NA NA 31106 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 6.94e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31107 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 5.02e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31108 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 1.12e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31109 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 4.16e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31110 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 4.31e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31111 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 4.58e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31112 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 7.69e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31113 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 9.27e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31114 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 3.3e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31115 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 1.75e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31116 FUN_009611 581 10 5 790 357 ptg000004l:9300458-9303777 Q96AY4 1.16e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31117 FUN_029535 2 65 2 7 125 ptg000023l:3067990-3068845 P45436 2.26e-30 Cell death protein 3 (EC 3.4.22.60) (Caspase ced-3) [Cleaved into: Cell death protein 3 subunit p17; Cell death protein 3 subunit p15; Cell death protein 3 subunit p13] Caenorhabditis remanei (Caenorhabditis vulgaris) actin filament depolymerization [GO:0030042]; activation of cysteine-type endopeptidase activity [GO:0097202]; apoptotic process involved in development [GO:1902742]; defense response to Gram-negative bacterium [GO:0050829]; embryo development ending in birth or egg hatching [GO:0009792]; muscle cell cellular homeostasis [GO:0046716]; negative regulation of cellular response to manganese ion [GO:1905803]; negative regulation of execution phase of apoptosis [GO:1900118]; positive regulation of apoptotic process involved in development [GO:1904747]; positive regulation of cellular response to gamma radiation [GO:1905845]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of oviposition [GO:1901046]; positive regulation of protein processing [GO:0010954]; positive regulation of synapse pruning [GO:1905808]; protein autoprocessing [GO:0016540]; protein catabolic process [GO:0030163]; regulation of cell adhesion [GO:0030155]; regulation of cell fate specification [GO:0042659]; regulation of development, heterochronic [GO:0040034]; regulation of locomotion [GO:0040012]; regulation of protein stability [GO:0031647]; regulation of vulval development [GO:0040028] GO:0005739; GO:0008303; GO:0008656; GO:0009792; GO:0010954; GO:0016540; GO:0030042; GO:0030155; GO:0030163; GO:0031647; GO:0031965; GO:0040012; GO:0040028; GO:0040034; GO:0042659; GO:0042802; GO:0043204; GO:0043525; GO:0046716; GO:0048471; GO:0050829; GO:0097200; GO:0097202; GO:0098793; GO:1900118; GO:1901046; GO:1902742; GO:1904747; GO:1905803; GO:1905808; GO:1905845 31118 FUN_029534 49 52 56 18 86 ptg000023l:3066026-3067916 Q8IWT6 1.18e-74 Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1) Homo sapiens (Human) anion transmembrane transport [GO:0098656]; anion transport [GO:0006820]; aspartate transmembrane transport [GO:0015810]; cell volume homeostasis [GO:0006884]; cellular glucose homeostasis [GO:0001678]; chloride transmembrane transport [GO:1902476]; cyclic-GMP-AMP transmembrane import across plasma membrane [GO:0140361]; positive regulation of insulin secretion [GO:0032024]; positive regulation of myoblast differentiation [GO:0045663]; pre-B cell differentiation [GO:0002329]; protein hexamerization [GO:0034214]; response to osmotic stress [GO:0006970]; spermatogenesis [GO:0007283]; taurine transport [GO:0015734] GO:0001678; GO:0002329; GO:0005225; GO:0005765; GO:0005886; GO:0006820; GO:0006884; GO:0006970; GO:0007283; GO:0009986; GO:0015734; GO:0015810; GO:0016020; GO:0032024; GO:0034214; GO:0034702; GO:0042802; GO:0045663; GO:0098656; GO:0140360; GO:0140361; GO:1902476 31119 FUN_029537 1227 776 518 826 759 NA NA NA NA NA NA NA 31120 FUN_029536 241 85 119 58 92 NA NA NA NA NA NA NA 31121 FUN_029531 8 0 17 0 95 NA NA NA NA NA NA NA 31122 FUN_029530 192 111 147 232 272 NA NA NA NA NA NA NA 31123 FUN_029533 0 15 0 0 43 NA NA NA NA NA NA NA 31124 FUN_029532 95 66 38 70 161 ptg000023l:3045243-3047214 P16157 3.96e-25 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 31125 FUN_029532 95 66 38 70 161 ptg000023l:3045243-3047214 P16157 1.87e-24 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 31126 FUN_029532 95 66 38 70 161 ptg000023l:3045243-3047214 P16157 3.05e-24 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 31127 FUN_029532 95 66 38 70 161 ptg000023l:3045243-3047214 P16157 5.79e-21 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 31128 FUN_029532 95 66 38 70 161 ptg000023l:3045243-3047214 P16157 7.71e-21 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 31129 FUN_029539 741 142 148 316 297 NA NA NA NA NA NA NA 31130 FUN_029538 152 169 57 67 94 NA NA NA NA NA NA NA 31131 FUN_039829 1378 1299 1263 1180 1210 NA NA NA NA NA NA NA 31132 FUN_016019 68 49 51 105 169 NA NA NA NA NA NA NA 31133 FUN_016015 416 316 153 399 491 NA NA NA NA NA NA NA 31134 FUN_042377 4 0 0 1 16 NA NA NA NA NA NA NA 31135 FUN_016010 746 2046 295 1461 1093 NA NA NA NA NA NA NA 31136 FUN_016011 1507 0 0 4099 1159 ptg000010l:562362-638956 P21328 2.42e-31 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 31137 FUN_016011 1507 0 0 4099 1159 ptg000010l:562362-638956 P21328 2.42e-31 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 31138 FUN_016012 202 0 0 251 81 NA NA NA NA NA NA NA 31139 FUN_041468 27 17 15 50 99 NA NA NA NA NA NA NA 31140 FUN_041465 191 49 59 163 176 ptg000035l:3951894-3957633 P51175 8.48e-31 Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) Mus musculus (Mouse) heme biosynthetic process [GO:0006783]; porphyrin-containing compound biosynthetic process [GO:0006779]; protoporphyrinogen IX biosynthetic process [GO:0006782]; protoporphyrinogen IX metabolic process [GO:0046501]; response to xenobiotic stimulus [GO:0009410] GO:0004729; GO:0005739; GO:0005743; GO:0006779; GO:0006782; GO:0006783; GO:0009410; GO:0016491; GO:0031966; GO:0046501 31141 FUN_041467 58 35 160 6 100 NA NA NA NA NA NA NA 31142 FUN_041466 1241 849 323 1235 591 NA NA NA NA NA NA NA 31143 FUN_026725 84 70 19 66 74 NA NA NA NA NA NA NA 31144 FUN_013940 0 5 0 0 26 NA NA NA NA NA NA NA 31145 FUN_028669 6 0 0 0 11 NA NA NA NA NA NA NA 31146 FUN_041463 9247 3860 2726 8402 6986 NA NA NA NA NA NA NA 31147 FUN_026208 373 155 270 662 482 ptg000020l:5995845-5996852 Q60847 8.04e-21 Collagen alpha-1(XII) chain Mus musculus (Mouse) cell adhesion [GO:0007155]; endodermal cell differentiation [GO:0035987] GO:0005595; GO:0005615; GO:0007155; GO:0035987; GO:0062023 31148 FUN_026209 391 268 407 1547 1244 NA NA NA NA NA NA NA 31149 FUN_026206 0 7 4 0 15 NA NA NA NA NA NA NA 31150 FUN_026204 82 69 87 17 45 NA NA NA NA NA NA NA 31151 FUN_026203 164 252 815 464 1302 NA NA NA NA NA NA NA 31152 FUN_026200 444 311 556 783 660 ptg000020l:5864981-5883972 B3EWY9 1.63e-24 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 31153 FUN_026200 444 311 556 783 660 ptg000020l:5864981-5883972 B3EWY9 6.9e-21 Mucin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) cell-matrix adhesion [GO:0007160] GO:0005509; GO:0007160; GO:0016020 31154 FUN_026201 436 599 1332 922 1469 NA NA NA NA NA NA NA 31155 FUN_022189 28 62 68 61 70 NA NA NA NA NA NA NA 31156 FUN_022188 22987 24402 14966 19081 18774 NA NA NA NA NA NA NA 31157 FUN_022181 87 50 78 52 28 NA NA NA NA NA NA NA 31158 FUN_022180 52 26 110 212 148 NA NA NA NA NA NA NA 31159 FUN_022183 1798 1599 2187 1015 1663 NA NA NA NA NA NA NA 31160 FUN_022185 2555 2122 2376 2803 847 ptg000016l:6099036-6106655 Q38912 4.95e-29 Rac-like GTP-binding protein ARAC3 (AtRAC1) (GTPase protein ROP6) Arabidopsis thaliana (Mouse-ear cress) actin filament organization [GO:0007015]; auxin-activated signaling pathway [GO:0009734]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; positive gravitropism [GO:0009958]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of cell shape [GO:0008360]; root hair elongation [GO:0048767]; root hair initiation [GO:0048766]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005525; GO:0005634; GO:0005730; GO:0005737; GO:0005819; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0009734; GO:0009958; GO:0010928; GO:0019003; GO:0019901; GO:0030427; GO:0030865; GO:0031410; GO:0032956; GO:0042995; GO:0048766; GO:0048767 31161 FUN_022184 137 323 490 699 322 ptg000016l:6093239-6095141 Q9JJL4 1.08e-26 Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; cellular response to insulin stimulus [GO:0032869]; cortical actin cytoskeleton organization [GO:0030866]; endocytosis [GO:0006897]; establishment or maintenance of cell polarity [GO:0007163]; GTP metabolic process [GO:0046039]; insulin receptor signaling pathway [GO:0008286]; negative regulation of protein localization to plasma membrane [GO:1903077]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell shape [GO:0008360]; small GTPase mediated signal transduction [GO:0007264] GO:0003924; GO:0005522; GO:0005525; GO:0005737; GO:0005884; GO:0005886; GO:0006897; GO:0007163; GO:0007264; GO:0008286; GO:0008360; GO:0030036; GO:0030866; GO:0032427; GO:0032869; GO:0045121; GO:0045944; GO:0046039; GO:0046326; GO:0051491; GO:1903077 31162 FUN_022187 3423 2427 1561 2630 2367 NA NA NA NA NA NA NA 31163 FUN_022186 2474 1717 1120 1693 1364 NA NA NA NA NA NA NA 31164 FUN_017658 0 0 0 44 33 NA NA NA NA NA NA NA 31165 FUN_017655 0 0 0 0 23 NA NA NA NA NA NA NA 31166 FUN_017654 7 0 6 0 113 NA NA NA NA NA NA NA 31167 FUN_017657 0 3 4 7 8 NA NA NA NA NA NA NA 31168 FUN_017656 0 0 0 0 7 NA NA NA NA NA NA NA 31169 FUN_023582 19 32 34 26 1 NA NA NA NA NA NA NA 31170 FUN_023583 409 398 318 410 652 ptg000017l:9548877-9552106 Q58EK5 7.1e-57 Tudor domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 31171 FUN_023583 409 398 318 410 652 ptg000017l:9548877-9552106 Q58EK5 1.36e-42 Tudor domain-containing protein 1 Danio rerio (Zebrafish) (Brachydanio rerio) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; P granule organization [GO:0030719]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0005737; GO:0007281; GO:0007283; GO:0030719; GO:0031047; GO:0034584; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 31172 FUN_023580 115 91 0 125 65 NA NA NA NA NA NA NA 31173 FUN_023581 1129 656 567 952 615 NA NA NA NA NA NA NA 31174 FUN_023586 752 484 330 1294 734 NA NA NA NA NA NA NA 31175 FUN_023587 11773 7395 5430 7749 7315 ptg000017l:9578427-9597268 Q9VU68 5.54e-36 Actin-interacting protein 1 (AIP1) (Protein flare) Drosophila melanogaster (Fruit fly) actin filament depolymerization [GO:0030042]; border follicle cell migration [GO:0007298]; establishment of planar polarity [GO:0001736]; imaginal disc-derived wing hair organization [GO:0035317]; locomotion [GO:0040011]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; positive regulation of actin filament depolymerization [GO:0030836]; regulation of actin filament depolymerization [GO:0030834]; regulation of actin filament polymerization [GO:0030833]; sarcomere organization [GO:0045214] GO:0001736; GO:0005856; GO:0007298; GO:0030042; GO:0030833; GO:0030834; GO:0030836; GO:0030864; GO:0034316; GO:0035317; GO:0040011; GO:0045214; GO:0051015 31176 FUN_023584 182 84 162 117 250 ptg000017l:9552129-9553896 A9CPT4 1.79e-30 Tudor domain-containing protein 1 Oryzias latipes (Japanese rice fish) (Japanese killifish) DNA methylation involved in gamete generation [GO:0043046]; germ cell development [GO:0007281]; meiotic cell cycle [GO:0051321]; piRNA processing [GO:0034587]; RNA-mediated gene silencing [GO:0031047]; spermatogenesis [GO:0007283] GO:0007281; GO:0007283; GO:0031047; GO:0034587; GO:0043046; GO:0043186; GO:0046872; GO:0051321; GO:0071546 31177 FUN_023585 96 65 38 36 36 NA NA NA NA NA NA NA 31178 FUN_023588 786 572 368 988 906 NA NA NA NA NA NA NA 31179 FUN_023589 64 117 154 49 177 ptg000017l:9613734-9620032 Q14832 8.16e-165 Metabotropic glutamate receptor 3 (mGluR3) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; negative regulation of adenylate cyclase activity [GO:0007194]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of synaptic transmission, glutamatergic [GO:0051966] GO:0001640; GO:0001641; GO:0004930; GO:0005246; GO:0005886; GO:0007194; GO:0007216; GO:0007268; GO:0008066; GO:0010467; GO:0014069; GO:0030424; GO:0042734; GO:0043197; GO:0045211; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 31180 FUN_022233 0 11 8 44 27 NA NA NA NA NA NA NA 31181 FUN_022231 39 16 13 0 0 NA NA NA NA NA NA NA 31182 FUN_022230 0 11 11 34 25 NA NA NA NA NA NA NA 31183 FUN_022237 4506 3054 2091 3875 2957 NA NA NA NA NA NA NA 31184 FUN_022236 78 51 31 103 52 NA NA NA NA NA NA NA 31185 FUN_022235 348 292 158 439 379 NA NA NA NA NA NA NA 31186 FUN_022234 0 8 12 0 34 NA NA NA NA NA NA NA 31187 FUN_022239 2864 3416 1484 2138 1499 NA NA NA NA NA NA NA 31188 FUN_022238 2985 1205 835 1844 1474 NA NA NA NA NA NA NA 31189 FUN_009573 74 8 57 4 0 NA NA NA NA NA NA NA 31190 FUN_041764 380 354 236 214 259 NA NA NA NA NA NA NA 31191 FUN_014300 16 9 2 13 10 NA NA NA NA NA NA NA 31192 FUN_019553 0 0 7 0 0 NA NA NA NA NA NA NA 31193 FUN_044025 670 3479 2533 2782 1825 NA NA NA NA NA NA NA 31194 FUN_019559 512 320 63 1200 802 NA NA NA NA NA NA NA 31195 FUN_044029 11 47 701 63 336 NA NA NA NA NA NA NA 31196 FUN_024176 22 48 38 0 28 NA NA NA NA NA NA NA 31197 FUN_024177 12 0 0 11 9 NA NA NA NA NA NA NA 31198 FUN_024174 2803 2458 1227 2079 1193 NA NA NA NA NA NA NA 31199 FUN_024175 296 226 157 400 425 NA NA NA NA NA NA NA 31200 FUN_024172 11 25 16 0 47 NA NA NA NA NA NA NA 31201 FUN_024173 45 73 5 131 84 NA NA NA NA NA NA NA 31202 FUN_024170 7 10 0 0 12 NA NA NA NA NA NA NA 31203 FUN_024171 0 0 0 0 6 NA NA NA NA NA NA NA 31204 FUN_030667 745 462 303 414 358 NA NA NA NA NA NA NA 31205 FUN_030665 367 324 267 173 332 NA NA NA NA NA NA NA 31206 FUN_030664 2 1 1 6 8 NA NA NA NA NA NA NA 31207 FUN_030663 3407 2986 1526 2427 2399 ptg000023l:14496040-14505553 P20650 3.78e-102 Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA) Rattus norvegicus (Rat) cellular response to transforming growth factor beta stimulus [GO:0071560]; dephosphorylation [GO:0016311]; N-terminal protein myristoylation [GO:0006499]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of SMAD protein complex assembly [GO:0010991]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein export from nucleus [GO:0046827]; protein dephosphorylation [GO:0006470]; protein export from nucleus [GO:0006611] GO:0000287; GO:0004721; GO:0004722; GO:0005634; GO:0005829; GO:0006470; GO:0006499; GO:0006611; GO:0008022; GO:0010991; GO:0016020; GO:0016311; GO:0017018; GO:0030145; GO:0030512; GO:0030514; GO:0033192; GO:0035970; GO:0043005; GO:0043124; GO:0044325; GO:0045893; GO:0046827; GO:0070412; GO:0071560; GO:0090263; GO:1901223 31208 FUN_030662 1547 1594 1230 1698 931 NA NA NA NA NA NA NA 31209 FUN_030668 9842 17772 8018 9929 4916 NA NA NA NA NA NA NA 31210 FUN_029185 156 101 165 278 218 NA NA NA NA NA NA NA 31211 FUN_029187 1816 894 766 982 873 NA NA NA NA NA NA NA 31212 FUN_026119 208 293 472 714 291 NA NA NA NA NA NA NA 31213 FUN_033799 17 3 6 58 52 NA NA NA NA NA NA NA 31214 FUN_021190 0 0 0 0 42 NA NA NA NA NA NA NA 31215 FUN_037473 8873 3539 5657 13911 9656 ptg000026l:10874265-10881872 B3EWZ7 8.13e-58 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31216 FUN_037472 304 66 63 70 125 ptg000026l:10864438-10867919 B3EWZ7 4.31e-46 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31217 FUN_037471 4908 1721 1461 4397 2318 ptg000026l:10850504-10856460 B3EX01 1.08e-42 CUB domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31218 FUN_037471 4908 1721 1461 4397 2318 ptg000026l:10850504-10856460 B3EX01 6.84e-36 CUB domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31219 FUN_037471 4908 1721 1461 4397 2318 ptg000026l:10850504-10856460 B3EX01 1.28e-23 CUB domain-containing protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31220 FUN_037470 168 14 39 105 69 ptg000026l:10845077-10848134 B3EWZ7 1.81e-50 Threonine-rich protein Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31221 FUN_037477 749 348 357 510 348 NA NA NA NA NA NA NA 31222 FUN_037476 914 299 454 516 501 NA NA NA NA NA NA NA 31223 FUN_037475 618 504 484 522 542 NA NA NA NA NA NA NA 31224 FUN_037474 6 20 17 14 0 NA NA NA NA NA NA NA 31225 FUN_005753 3001 2111 1536 2635 2879 ptg000001l:3652750-3700279 Q8BU03 2.25e-31 Periodic tryptophan protein 2 homolog Mus musculus (Mouse) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0000462; GO:0032040; GO:0034388 31226 FUN_005753 3001 2111 1536 2635 2879 ptg000001l:3652750-3700279 Q8BU03 2.25e-31 Periodic tryptophan protein 2 homolog Mus musculus (Mouse) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0000462; GO:0032040; GO:0034388 31227 FUN_005753 3001 2111 1536 2635 2879 ptg000001l:3652750-3700279 Q8BU03 7.04e-21 Periodic tryptophan protein 2 homolog Mus musculus (Mouse) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; ribosomal small subunit assembly [GO:0000028] GO:0000028; GO:0000462; GO:0032040; GO:0034388 31228 FUN_005751 2317 2397 1357 1929 2076 ptg000001l:3641796-3647052 Q8CBC7 9.66e-51 NA NA NA NA 31229 FUN_005751 2317 2397 1357 1929 2076 ptg000001l:3641796-3647052 Q8CBC7 1.9e-37 NA NA NA NA 31230 FUN_005750 115 61 60 44 36 NA NA NA NA NA NA NA 31231 FUN_005757 13 0 37 36 191 NA NA NA NA NA NA NA 31232 FUN_005755 0 0 4 1 11 NA NA NA NA NA NA NA 31233 FUN_005754 0 0 32 3 4 NA NA NA NA NA NA NA 31234 FUN_001449 220 248 107 268 122 ntLink_6:12526012-12527560 P58912 1.41e-75 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31235 FUN_001448 1672 1020 938 1108 1071 NA NA NA NA NA NA NA 31236 FUN_001443 8 223 3 1 7 ntLink_6:12466384-12467803 P58912 3.4e-87 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31237 FUN_001442 20 7 0 0 0 ntLink_6:12454762-12459463 P58912 2.49e-62 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31238 FUN_001441 0 15 0 0 0 ntLink_6:12451138-12454590 Q76DT2 3.56e-30 DELTA-thalatoxin-Avl2a (DELTA-TATX-Avl2a) (Toxin AvTX-60A) (Av60A) Actineria villosa (Okinawan sea anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31239 FUN_001440 0 13 0 0 3 ntLink_6:12446947-12451119 P58912 5.7e-28 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31240 FUN_001447 2604 1962 2004 3773 3421 NA NA NA NA NA NA NA 31241 FUN_001446 515 313 161 716 349 NA NA NA NA NA NA NA 31242 FUN_001445 10 146 0 0 27 ntLink_6:12480881-12483466 P58912 1.84e-82 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31243 FUN_001444 20 6 0 0 0 ntLink_6:12470340-12475057 P58912 2.5e-62 DELTA-alicitoxin-Pse2b (DELTA-ALTX-Pse2b) (Toxin PsTX-60B) (PTX60B) Phyllodiscus semoni (Night anemone) hemolysis in another organism [GO:0044179] GO:0005576; GO:0042151; GO:0044179; GO:0090729 31244 FUN_040258 653 508 148 609 687 NA NA NA NA NA NA NA 31245 FUN_028086 0 81 0 16 0 NA NA NA NA NA NA NA 31246 FUN_028087 1950 1524 1026 1870 1072 ptg000021l:15663863-15669112 Q9DAJ2 1.11e-22 Tektin-1 Mus musculus (Mouse) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294] GO:0005879; GO:0015630; GO:0031514; GO:0060271; GO:0060294 31247 FUN_004088 9281 8260 5511 8519 6179 ntLink_8:19080122-19105550 Q0KIA2 3.01e-51 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 31248 FUN_004088 9281 8260 5511 8519 6179 ntLink_8:19080122-19105550 Q0KIA2 1.85e-49 PP2C-like domain-containing protein CG9801 Drosophila melanogaster (Fruit fly) NA NA 31249 FUN_004089 770 281 204 218 212 NA NA NA NA NA NA NA 31250 FUN_004080 12 11 56 35 34 NA NA NA NA NA NA NA 31251 FUN_004081 14 12 18 0 18 ntLink_8:18982284-18983100 Q3B8D7 7.61e-24 Dynein light chain Tctex-type 5-A (Tctex1 domain-containing protein 1-A) Xenopus laevis (African clawed frog) NA NA 31252 FUN_004082 276 134 341 250 372 ntLink_8:18985575-18986212 A2VDD2 2.33e-23 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 31253 FUN_004083 3150 1693 1584 1567 1407 ntLink_8:18989336-18999141 Q9ET22 6.96e-21 Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase) Mus musculus (Mouse) lysosomal protein catabolic process [GO:1905146]; protein catabolic process [GO:0030163]; proteolysis [GO:0006508] GO:0004177; GO:0005576; GO:0005764; GO:0005794; GO:0005829; GO:0006508; GO:0008236; GO:0008239; GO:0030163; GO:0031410; GO:0031982; GO:0043231; GO:1905146 31254 FUN_004084 947 875 744 1326 880 ntLink_8:18999539-19036164 Q03650 3.84e-59 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 31255 FUN_004084 947 875 744 1326 880 ntLink_8:18999539-19036164 Q03650 2.74e-58 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 31256 FUN_004084 947 875 744 1326 880 ntLink_8:18999539-19036164 Q03650 2.43e-55 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 31257 FUN_004084 947 875 744 1326 880 ntLink_8:18999539-19036164 Q03650 5.78e-55 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 31258 FUN_004084 947 875 744 1326 880 ntLink_8:18999539-19036164 Q03650 1.14e-45 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 31259 FUN_004085 636 868 780 2204 1997 NA NA NA NA NA NA NA 31260 FUN_004086 420 218 424 689 563 NA NA NA NA NA NA NA 31261 FUN_004087 768 1034 272 243 671 NA NA NA NA NA NA NA 31262 FUN_018096 0 0 0 0 7 NA NA NA NA NA NA NA 31263 FUN_018090 1852 1053 892 2466 2309 ptg000012l:4286572-4295336 A7DZP8 1.19e-37 Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mGPD) Mesocricetus auratus (Golden hamster) glycerol catabolic process [GO:0019563]; glycerol-3-phosphate metabolic process [GO:0006072] GO:0004368; GO:0005509; GO:0005739; GO:0006072; GO:0009331; GO:0019563; GO:0052591 31264 FUN_018090 1852 1053 892 2466 2309 ptg000012l:4286572-4295336 A7DZP8 5.24e-25 Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (mGPD) Mesocricetus auratus (Golden hamster) glycerol catabolic process [GO:0019563]; glycerol-3-phosphate metabolic process [GO:0006072] GO:0004368; GO:0005509; GO:0005739; GO:0006072; GO:0009331; GO:0019563; GO:0052591 31265 FUN_018091 1232 600 692 1042 979 ptg000012l:4298859-4342060 E7FAW3 1.96e-41 Neurobeachin-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) platelet formation [GO:0030220]; protein localization [GO:0008104] GO:0005783; GO:0005829; GO:0008104; GO:0016020; GO:0019901; GO:0030220 31266 FUN_018091 1232 600 692 1042 979 ptg000012l:4298859-4342060 E7FAW3 3.3e-32 Neurobeachin-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) platelet formation [GO:0030220]; protein localization [GO:0008104] GO:0005783; GO:0005829; GO:0008104; GO:0016020; GO:0019901; GO:0030220 31267 FUN_018091 1232 600 692 1042 979 ptg000012l:4298859-4342060 E7FAW3 2.14e-26 Neurobeachin-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) platelet formation [GO:0030220]; protein localization [GO:0008104] GO:0005783; GO:0005829; GO:0008104; GO:0016020; GO:0019901; GO:0030220 31268 FUN_018091 1232 600 692 1042 979 ptg000012l:4298859-4342060 E7FAW3 2.01e-21 Neurobeachin-like protein 2 Danio rerio (Zebrafish) (Brachydanio rerio) platelet formation [GO:0030220]; protein localization [GO:0008104] GO:0005783; GO:0005829; GO:0008104; GO:0016020; GO:0019901; GO:0030220 31269 FUN_033886 3987 2171 2997 3895 4455 NA NA NA NA NA NA NA 31270 FUN_033887 1236 811 966 1198 1128 NA NA NA NA NA NA NA 31271 FUN_033884 2336 1174 1119 854 585 NA NA NA NA NA NA NA 31272 FUN_033885 1583 1264 750 1077 961 ptg000024l:2261433-2265853 Q9NTG7 1.51e-30 NAD-dependent protein deacetylase sirtuin-3, mitochondrial (hSIRT3) (EC 2.3.1.286) (Regulatory protein SIR2 homolog 3) (SIR2-like protein 3) Homo sapiens (Human) aerobic respiration [GO:0009060]; peptidyl-lysine deacetylation [GO:0034983]; positive regulation of catalase activity [GO:1902553]; positive regulation of ceramide biosynthetic process [GO:2000304]; positive regulation of superoxide dismutase activity [GO:1901671]; protein deacetylation [GO:0006476] GO:0005634; GO:0005654; GO:0005739; GO:0005759; GO:0006476; GO:0008270; GO:0009060; GO:0016740; GO:0017136; GO:0032991; GO:0034979; GO:0034983; GO:0043565; GO:0070403; GO:1901671; GO:1902553; GO:2000304 31273 FUN_033882 430 467 216 346 243 ptg000024l:2225598-2238379 Q09081 1.07e-136 Potassium voltage-gated channel subfamily A member 2 (KC22) (Voltage-gated potassium channel subunit Kv1.2) Oryctolagus cuniculus (Rabbit) neuronal action potential [GO:0019228]; optic nerve structural organization [GO:0021633]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of circadian sleep/wake cycle, non-REM sleep [GO:0045188]; regulation of dopamine secretion [GO:0014059]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of pain [GO:0019233] GO:0005249; GO:0005251; GO:0005789; GO:0005886; GO:0008076; GO:0014059; GO:0019228; GO:0019233; GO:0021633; GO:0030027; GO:0030424; GO:0030425; GO:0031258; GO:0032809; GO:0033010; GO:0034765; GO:0042734; GO:0043194; GO:0043204; GO:0043679; GO:0044224; GO:0045188; GO:0051260; GO:0071805 31274 FUN_033883 1485 830 263 813 713 ptg000024l:2240273-2250510 A3BFT0 2.34e-27 Kinesin-like protein KIN-14N Oryza sativa subsp. japonica (Rice) microtubule-based movement [GO:0007018]; spindle assembly [GO:0051225] GO:0003777; GO:0005524; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:0051225 31275 FUN_033880 5597 3547 2823 5504 5498 NA NA NA NA NA NA NA 31276 FUN_033881 249 159 129 330 192 ptg000024l:2215955-2221276 Q8VBX0 3.59e-30 Ankyrin repeat and SOCS box protein 13 (ASB-13) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein ubiquitination [GO:0016567] GO:0016567; GO:0035556 31277 FUN_033888 2900 2936 1078 4148 3356 NA NA NA NA NA NA NA 31278 FUN_033889 279 135 187 412 922 NA NA NA NA NA NA NA 31279 FUN_031954 11 67 7 169 85 NA NA NA NA NA NA NA 31280 FUN_031955 0 20 0 38 38 NA NA NA NA NA NA NA 31281 FUN_031952 217 0 30 193 292 NA NA NA NA NA NA NA 31282 FUN_031953 3843 4248 847 1706 1841 NA NA NA NA NA NA NA 31283 FUN_031950 4829 4385 2028 3998 5628 ptg000023l:27057001-27063512 P62193 1.08e-21 26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1) Rattus norvegicus (Rat) negative regulation of neuron death [GO:1901215]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161] GO:0000502; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0005838; GO:0008540; GO:0016020; GO:0016887; GO:0017025; GO:0022624; GO:0036402; GO:0043161; GO:1901215 31284 FUN_031951 51 0 7 10 25 NA NA NA NA NA NA NA 31285 FUN_018320 122 34 100 288 92 ptg000012l:7650523-7655028 Q9Y6N7 8.87e-22 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 31286 FUN_018321 0 0 0 9 0 NA NA NA NA NA NA NA 31287 FUN_018322 92 32 107 108 82 ptg000012l:7666627-7679662 O89026 7.53e-21 Roundabout homolog 1 Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; endocardial cushion formation [GO:0003272]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; kidney development [GO:0001822]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; regulation of dendrite morphogenesis [GO:0048814]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281]; ventricular septum morphogenesis [GO:0060412] GO:0001822; GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0003281; GO:0005737; GO:0005886; GO:0006919; GO:0007156; GO:0007411; GO:0007507; GO:0008046; GO:0008285; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0021891; GO:0030275; GO:0030336; GO:0030424; GO:0030673; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043025; GO:0043406; GO:0048814; GO:0050772; GO:0050925; GO:0060412; GO:0060763; GO:0060976; GO:0070100; GO:1900748 31288 FUN_018323 163 14 61 61 81 ptg000012l:7684206-7694209 Q9Y6N7 3.02e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 31289 FUN_018326 95 0 56 49 10 NA NA NA NA NA NA NA 31290 FUN_000351 943 364 445 509 1171 NA NA NA NA NA NA NA 31291 FUN_003706 43283 20603 6484 9469 5121 NA NA NA NA NA NA NA 31292 FUN_036706 0 0 0 0 14 NA NA NA NA NA NA NA 31293 FUN_003703 13956 6143 1848 2922 2323 NA NA NA NA NA NA NA 31294 FUN_010503 8 11 4 54 16 NA NA NA NA NA NA NA 31295 FUN_003701 944 720 537 1319 192 NA NA NA NA NA NA NA 31296 FUN_041402 141 67 40 56 26 NA NA NA NA NA NA NA 31297 FUN_010931 1712 1052 1013 1555 1974 NA NA NA NA NA NA NA 31298 FUN_040339 0 0 0 22 18 NA NA NA NA NA NA NA 31299 FUN_010930 621 383 276 356 425 NA NA NA NA NA NA NA 31300 FUN_010932 52 70 34 108 84 ptg000007l:4435914-4440446 A0A2P1BRQ0 3.39e-86 Cytolytic toxin-alpha (Sp-CTx-alpha) Scorpaena plumieri (Spotted scorpionfish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 31301 FUN_041401 151 100 47 35 30 NA NA NA NA NA NA NA 31302 FUN_007063 334 374 151 95 248 ptg000001l:19994492-19995647 Q568G4 3.48e-31 EF-hand calcium-binding domain-containing protein 11 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005509 31303 FUN_007062 5108 1719 2109 3225 2886 NA NA NA NA NA NA NA 31304 FUN_007061 398 389 213 319 328 NA NA NA NA NA NA NA 31305 FUN_007060 72 42 56 59 102 ptg000001l:19939790-19942319 G3M4F8 2.48e-42 Octopamine receptor beta-2R (CsOA2B2) Chilo suppressalis (Asiatic rice borer moth) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; cellular response to amine stimulus [GO:0071418]; octopamine signaling pathway [GO:0071927]; tyramine signaling pathway [GO:0071928] GO:0004989; GO:0005886; GO:0007189; GO:0008226; GO:0016020; GO:0071418; GO:0071927; GO:0071928 31306 FUN_043229 9 18 0 0 0 NA NA NA NA NA NA NA 31307 FUN_010937 142 99 131 106 43 ptg000007l:4491321-4496782 A0ZSK4 4.08e-63 Neoverrucotoxin subunit beta (NeoVTX subunit beta) Synanceia verrucosa (Reef stonefish) hemolysis in another organism [GO:0044179] GO:0005576; GO:0044179; GO:0090729 31308 FUN_007065 365 75 166 148 215 ptg000001l:20012969-20015124 Q5RC69 2.57e-35 Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220] GO:0004132; GO:0006220; GO:0008270; GO:0009165 31309 FUN_007065 365 75 166 148 215 ptg000001l:20012969-20015124 Q5RC69 1.73e-26 Deoxycytidylate deaminase (EC 3.5.4.12) (dCMP deaminase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) nucleotide biosynthetic process [GO:0009165]; pyrimidine nucleotide metabolic process [GO:0006220] GO:0004132; GO:0006220; GO:0008270; GO:0009165 31310 FUN_007064 1581 1479 715 1596 1800 NA NA NA NA NA NA NA 31311 FUN_043225 4338 3044 1920 3601 3137 NA NA NA NA NA NA NA 31312 FUN_043224 4161 3104 1519 2846 1782 NA NA NA NA NA NA NA 31313 FUN_043227 579 605 161 601 546 ptg000047l:5623423-5627022 Q96AY4 2.73e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31314 FUN_043227 579 605 161 601 546 ptg000047l:5623423-5627022 Q96AY4 4.4e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31315 FUN_043227 579 605 161 601 546 ptg000047l:5623423-5627022 Q96AY4 1.57e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31316 FUN_043227 579 605 161 601 546 ptg000047l:5623423-5627022 Q96AY4 3.17e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31317 FUN_043226 1259 616 302 183 513 ptg000047l:5609334-5613434 Q96AY4 5.26e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31318 FUN_043226 1259 616 302 183 513 ptg000047l:5609334-5613434 Q96AY4 1.84e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31319 FUN_043226 1259 616 302 183 513 ptg000047l:5609334-5613434 Q96AY4 2.28e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31320 FUN_043226 1259 616 302 183 513 ptg000047l:5609334-5613434 Q96AY4 1.13e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31321 FUN_043221 0 35 18 35 10 NA NA NA NA NA NA NA 31322 FUN_043220 214 100 25 207 79 ptg000047l:5540846-5544486 Q969U6 4.74e-25 F-box/WD repeat-containing protein 5 (F-box and WD-40 domain-containing protein 5) Homo sapiens (Human) proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of centrosome duplication [GO:0010824]; regulation of mitotic nuclear division [GO:0007088]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0005737; GO:0005829; GO:0007088; GO:0010824; GO:0016567; GO:0019005; GO:0019901; GO:0031146; GO:0043161; GO:0080008 31323 FUN_043223 106 56 33 44 98 NA NA NA NA NA NA NA 31324 FUN_043222 954 1186 857 943 694 NA NA NA NA NA NA NA 31325 FUN_043725 5 0 0 0 8 NA NA NA NA NA NA NA 31326 FUN_019051 0 0 0 0 13 NA NA NA NA NA NA NA 31327 FUN_041400 70 41 48 78 28 NA NA NA NA NA NA NA 31328 FUN_019057 0 0 0 0 9 NA NA NA NA NA NA NA 31329 FUN_013017 0 0 0 21 17 NA NA NA NA NA NA NA 31330 FUN_013015 18 10 27 0 148 NA NA NA NA NA NA NA 31331 FUN_013019 2 1 9 1 1 NA NA NA NA NA NA NA 31332 FUN_013018 16 4 0 0 64 NA NA NA NA NA NA NA 31333 FUN_034829 1226 742 516 747 1105 NA NA NA NA NA NA NA 31334 FUN_034828 6200 4851 2676 5702 4766 ptg000025l:534418-542171 P12345 7.59e-29 Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A) Oryctolagus cuniculus (Rabbit) 2-oxoglutarate metabolic process [GO:0006103]; aspartate metabolic process [GO:0006531]; biosynthetic process [GO:0009058]; glutamate metabolic process [GO:0006536]; lipid transport [GO:0006869]; protein folding [GO:0006457] GO:0004069; GO:0005739; GO:0005759; GO:0005886; GO:0006103; GO:0006457; GO:0006531; GO:0006536; GO:0006869; GO:0009058; GO:0016212; GO:0030170 31335 FUN_043722 15 0 6 0 5 NA NA NA NA NA NA NA 31336 FUN_034821 761 563 211 522 343 NA NA NA NA NA NA NA 31337 FUN_034820 663 526 217 254 320 NA NA NA NA NA NA NA 31338 FUN_034823 324 175 340 436 336 NA NA NA NA NA NA NA 31339 FUN_034822 69 84 43 29 74 ptg000025l:462008-462881 Q8IN35 3.27e-26 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 31340 FUN_034825 1724 633 5 0 0 NA NA NA NA NA NA NA 31341 FUN_034824 29 0 39 24 0 NA NA NA NA NA NA NA 31342 FUN_034827 63 0 0 0 84 NA NA NA NA NA NA NA 31343 FUN_034826 234 65 0 0 9 NA NA NA NA NA NA NA 31344 FUN_043597 1127 435 637 1066 1161 NA NA NA NA NA NA NA 31345 FUN_043596 1859 708 610 1344 1073 NA NA NA NA NA NA NA 31346 FUN_043595 1075 276 1028 1534 883 NA NA NA NA NA NA NA 31347 FUN_043594 1889 380 2216 1520 943 ptg000047l:10425952-10436309 P00760 5.4e-32 Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-I) (Beta-trypsin) (Cationic trypsin) (Pretrypsinogen I) (Trypsin I) (Trypsin-I) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2] Bos taurus (Bovine) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004175; GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872; GO:0097180; GO:0097655 31348 FUN_043593 2021 1883 2363 3539 3318 NA NA NA NA NA NA NA 31349 FUN_043592 1387 1120 639 1015 1000 NA NA NA NA NA NA NA 31350 FUN_043591 46 306 0 49 15 NA NA NA NA NA NA NA 31351 FUN_043590 153 174 0 74 182 NA NA NA NA NA NA NA 31352 FUN_043599 2139 1080 1029 1682 1688 NA NA NA NA NA NA NA 31353 FUN_043598 130 201 354 174 189 ptg000047l:10557485-10562661 O60235 2.07e-21 Transmembrane protease serine 11D (EC 3.4.21.-) (Airway trypsin-like protease) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain] Homo sapiens (Human) proteolysis [GO:0006508]; respiratory gaseous exchange by respiratory system [GO:0007585] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0007585; GO:0008233; GO:0070062 31354 FUN_030309 5 0 6 0 23 ptg000023l:10580160-10580923 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31355 FUN_030305 5 0 6 1 23 ptg000023l:10572056-10572819 P84239 1.14e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31356 FUN_030307 4 0 5 0 25 ptg000023l:10576108-10576871 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31357 FUN_030301 6 1 6 0 19 ptg000023l:10563952-10564715 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31358 FUN_030303 4 0 5 0 21 ptg000023l:10568004-10568767 P84239 1.14e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31359 FUN_036462 0 0 0 0 13 NA NA NA NA NA NA NA 31360 FUN_036460 20 0 0 0 0 NA NA NA NA NA NA NA 31361 FUN_036467 0 0 6 0 1 NA NA NA NA NA NA NA 31362 FUN_036465 29 0 13 0 0 NA NA NA NA NA NA NA 31363 FUN_036469 163 148 0 243 0 NA NA NA NA NA NA NA 31364 FUN_006399 0 0 4 0 7 NA NA NA NA NA NA NA 31365 FUN_042172 2 17 2 16 45 NA NA NA NA NA NA NA 31366 FUN_042171 7 0 20 2 254 NA NA NA NA NA NA NA 31367 FUN_042176 3 0 5 1 6 NA NA NA NA NA NA NA 31368 FUN_042177 107 73 31 104 72 NA NA NA NA NA NA NA 31369 FUN_042174 5 73 166 36 20 NA NA NA NA NA NA NA 31370 FUN_042175 1127 620 386 849 1539 NA NA NA NA NA NA NA 31371 FUN_042178 0 0 0 0 25 NA NA NA NA NA NA NA 31372 FUN_006394 21 0 39 14 162 NA NA NA NA NA NA NA 31373 FUN_041431 654 433 115 953 259 NA NA NA NA NA NA NA 31374 FUN_023049 525 290 339 639 642 ptg000017l:3030006-3034295 Q5R7P4 0 Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) carbohydrate metabolic process [GO:0005975] GO:0004565; GO:0005764; GO:0005975 31375 FUN_023048 728 476 500 550 741 ptg000017l:3027616-3029710 Q4R7T7 2.48e-124 Tubulin delta chain (Delta-tubulin) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell projection organization [GO:0030030]; microtubule-based process [GO:0007017]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007017; GO:0030030; GO:0045880 31376 FUN_023048 728 476 500 550 741 ptg000017l:3027616-3029710 Q4R7T7 1.05e-33 Tubulin delta chain (Delta-tubulin) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) cell projection organization [GO:0030030]; microtubule-based process [GO:0007017]; positive regulation of smoothened signaling pathway [GO:0045880] GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005814; GO:0005874; GO:0005929; GO:0007017; GO:0030030; GO:0045880 31377 FUN_032186 1565 449 351 737 1933 ptg000023l:29580680-29597534 B3EX02 5.44e-30 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 31378 FUN_032187 27 17 0 25 23 ptg000023l:29598988-29600753 H9JW43 1.38e-24 Chitin deacetylase 8 (BmCDA8) (EC 3.5.1.41) (Chitin deacetylase 17) Bombyx mori (Silk moth) chitin catabolic process [GO:0006032]; polysaccharide catabolic process [GO:0000272] GO:0000272; GO:0004099; GO:0005615; GO:0006032; GO:0008270 31379 FUN_032180 81 7 0 1 7 NA NA NA NA NA NA NA 31380 FUN_036878 256 258 330 996 3071 NA NA NA NA NA NA NA 31381 FUN_029866 0 0 0 7 0 NA NA NA NA NA NA NA 31382 FUN_004879 45 2155 505 903 0 NA NA NA NA NA NA NA 31383 FUN_004878 123 36 21 0 0 NA NA NA NA NA NA NA 31384 FUN_032182 332 184 147 179 572 ptg000023l:29528115-29571204 B8V7S0 1.31e-74 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 31385 FUN_016198 504 133 252 951 906 NA NA NA NA NA NA NA 31386 FUN_004871 1011 666 564 3499 322 ntLink_8:28204639-28218905 Q19204 2.43e-25 A disintegrin and metalloproteinase with thrombospondin motifs adt-2 (ADAMTS adt-2) (EC 3.4.24.-) Caenorhabditis elegans collagen fibril organization [GO:0030199]; determination of adult lifespan [GO:0008340]; extracellular matrix organization [GO:0030198]; positive regulation of multicellular organism growth [GO:0040018]; proteolysis [GO:0006508]; regulation of cell size [GO:0008361] GO:0004222; GO:0005576; GO:0006508; GO:0008340; GO:0008361; GO:0030198; GO:0030199; GO:0031012; GO:0040018; GO:0046872 31387 FUN_004871 1011 666 564 3499 322 ntLink_8:28204639-28218905 Q19204 2.43e-25 A disintegrin and metalloproteinase with thrombospondin motifs adt-2 (ADAMTS adt-2) (EC 3.4.24.-) Caenorhabditis elegans collagen fibril organization [GO:0030199]; determination of adult lifespan [GO:0008340]; extracellular matrix organization [GO:0030198]; positive regulation of multicellular organism growth [GO:0040018]; proteolysis [GO:0006508]; regulation of cell size [GO:0008361] GO:0004222; GO:0005576; GO:0006508; GO:0008340; GO:0008361; GO:0030198; GO:0030199; GO:0031012; GO:0040018; GO:0046872 31388 FUN_004871 1011 666 564 3499 322 ntLink_8:28204639-28218905 Q19204 2.43e-25 A disintegrin and metalloproteinase with thrombospondin motifs adt-2 (ADAMTS adt-2) (EC 3.4.24.-) Caenorhabditis elegans collagen fibril organization [GO:0030199]; determination of adult lifespan [GO:0008340]; extracellular matrix organization [GO:0030198]; positive regulation of multicellular organism growth [GO:0040018]; proteolysis [GO:0006508]; regulation of cell size [GO:0008361] GO:0004222; GO:0005576; GO:0006508; GO:0008340; GO:0008361; GO:0030198; GO:0030199; GO:0031012; GO:0040018; GO:0046872 31389 FUN_004871 1011 666 564 3499 322 ntLink_8:28204639-28218905 Q19204 2.43e-25 A disintegrin and metalloproteinase with thrombospondin motifs adt-2 (ADAMTS adt-2) (EC 3.4.24.-) Caenorhabditis elegans collagen fibril organization [GO:0030199]; determination of adult lifespan [GO:0008340]; extracellular matrix organization [GO:0030198]; positive regulation of multicellular organism growth [GO:0040018]; proteolysis [GO:0006508]; regulation of cell size [GO:0008361] GO:0004222; GO:0005576; GO:0006508; GO:0008340; GO:0008361; GO:0030198; GO:0030199; GO:0031012; GO:0040018; GO:0046872 31390 FUN_004871 1011 666 564 3499 322 ntLink_8:28204639-28218905 Q19204 2.43e-25 A disintegrin and metalloproteinase with thrombospondin motifs adt-2 (ADAMTS adt-2) (EC 3.4.24.-) Caenorhabditis elegans collagen fibril organization [GO:0030199]; determination of adult lifespan [GO:0008340]; extracellular matrix organization [GO:0030198]; positive regulation of multicellular organism growth [GO:0040018]; proteolysis [GO:0006508]; regulation of cell size [GO:0008361] GO:0004222; GO:0005576; GO:0006508; GO:0008340; GO:0008361; GO:0030198; GO:0030199; GO:0031012; GO:0040018; GO:0046872 31391 FUN_004870 2806 1029 1313 1489 1480 ntLink_8:28177129-28198538 O35114 1.73e-63 Lysosome membrane protein 2 (85 kDa lysosomal membrane sialoglycoprotein) (LGP85) (Lysosome membrane protein II) (LIMP II) (Scavenger receptor class B member 2) Mus musculus (Mouse) aminophospholipid transport [GO:0015917]; gene expression [GO:0010467]; positive regulation of neuron projection development [GO:0010976]; protein targeting to lysosome [GO:0006622]; receptor-mediated endocytosis [GO:0006898]; regulation of cellular carbohydrate catabolic process [GO:0043471]; regulation of glucosylceramidase activity [GO:1905123]; sensory perception of sound [GO:0007605] GO:0001786; GO:0005044; GO:0005737; GO:0005765; GO:0005886; GO:0006622; GO:0006898; GO:0007605; GO:0010467; GO:0010976; GO:0015485; GO:0015917; GO:0019899; GO:0030666; GO:0031210; GO:0038024; GO:0042803; GO:0043202; GO:0043471; GO:0051087; GO:1905123 31392 FUN_004873 365 790 626 669 245 NA NA NA NA NA NA NA 31393 FUN_004872 176 453 314 101 154 NA NA NA NA NA NA NA 31394 FUN_004875 46 61 4 95 122 NA NA NA NA NA NA NA 31395 FUN_004874 0 0 0 0 8 NA NA NA NA NA NA NA 31396 FUN_004877 35 0 19 20 31 NA NA NA NA NA NA NA 31397 FUN_004876 178 2840 6931 575 544 NA NA NA NA NA NA NA 31398 FUN_010096 0 0 0 6 0 NA NA NA NA NA NA NA 31399 FUN_010097 2 3 0 4 6 NA NA NA NA NA NA NA 31400 FUN_012829 0 0 111 131 119 NA NA NA NA NA NA NA 31401 FUN_028091 0 7 37 0 10 ptg000021l:15702834-15709000 P24798 1.86e-52 Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3) Gallus gallus (Chicken) cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; sodium ion export across plasma membrane [GO:0036376] GO:0005391; GO:0005524; GO:0005783; GO:0005794; GO:0005886; GO:0006883; GO:0016887; GO:0019829; GO:0030007; GO:0036376; GO:0045202; GO:0046872; GO:1902600; GO:1990573 31402 FUN_028091 0 7 37 0 10 ptg000021l:15702834-15709000 P24798 7.47e-45 Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3) Gallus gallus (Chicken) cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; sodium ion export across plasma membrane [GO:0036376] GO:0005391; GO:0005524; GO:0005783; GO:0005794; GO:0005886; GO:0006883; GO:0016887; GO:0019829; GO:0030007; GO:0036376; GO:0045202; GO:0046872; GO:1902600; GO:1990573 31403 FUN_028091 0 7 37 0 10 ptg000021l:15702834-15709000 P24798 2.23e-26 Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3) Gallus gallus (Chicken) cellular potassium ion homeostasis [GO:0030007]; cellular sodium ion homeostasis [GO:0006883]; potassium ion import across plasma membrane [GO:1990573]; proton transmembrane transport [GO:1902600]; sodium ion export across plasma membrane [GO:0036376] GO:0005391; GO:0005524; GO:0005783; GO:0005794; GO:0005886; GO:0006883; GO:0016887; GO:0019829; GO:0030007; GO:0036376; GO:0045202; GO:0046872; GO:1902600; GO:1990573 31404 FUN_002847 0 0 0 0 6 NA NA NA NA NA NA NA 31405 FUN_002843 11 0 11 0 36 NA NA NA NA NA NA NA 31406 FUN_002849 0 0 21 12 58 NA NA NA NA NA NA NA 31407 FUN_036830 650 484 519 680 669 NA NA NA NA NA NA NA 31408 FUN_036910 2864 3759 1599 2964 1493 NA NA NA NA NA NA NA 31409 FUN_036831 742 526 397 687 446 NA NA NA NA NA NA NA 31410 FUN_005155 802 837 541 723 282 NA NA NA NA NA NA NA 31411 FUN_011329 0 7 0 0 0 NA NA NA NA NA NA NA 31412 FUN_011328 54 32 20 12 213 NA NA NA NA NA NA NA 31413 FUN_011327 0 30 0 0 0 NA NA NA NA NA NA NA 31414 FUN_036918 8539 9448 6809 5690 4481 NA NA NA NA NA NA NA 31415 FUN_011323 18 1 1 8 3 NA NA NA NA NA NA NA 31416 FUN_011321 16 0 30 0 182 ptg000007l:8831412-8835225 P08548 1.25e-62 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 31417 FUN_011320 0 0 0 0 13 NA NA NA NA NA NA NA 31418 FUN_005154 0 0 7 17 0 ntLink_8:31874157-31875078 Q924H0 8.86e-25 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 31419 FUN_000578 475 161 458 756 428 NA NA NA NA NA NA NA 31420 FUN_000579 467 220 335 578 618 NA NA NA NA NA NA NA 31421 FUN_008767 99 19 39 114 188 NA NA NA NA NA NA NA 31422 FUN_008766 636 147 83 216 115 NA NA NA NA NA NA NA 31423 FUN_008761 314 123 123 302 29 NA NA NA NA NA NA NA 31424 FUN_008760 0 0 0 144 94 NA NA NA NA NA NA NA 31425 FUN_008763 447 116 146 1207 235 NA NA NA NA NA NA NA 31426 FUN_008762 0 54 15 3 0 NA NA NA NA NA NA NA 31427 FUN_000570 1955 1366 848 2227 1218 NA NA NA NA NA NA NA 31428 FUN_000572 0 0 0 83 19 NA NA NA NA NA NA NA 31429 FUN_000573 737 859 735 245 682 NA NA NA NA NA NA NA 31430 FUN_008769 1857 914 1308 1613 1276 NA NA NA NA NA NA NA 31431 FUN_008768 1161 518 598 1512 628 NA NA NA NA NA NA NA 31432 FUN_000576 47 0 28 35 9 NA NA NA NA NA NA NA 31433 FUN_000577 461 473 291 840 285 NA NA NA NA NA NA NA 31434 FUN_041524 634 241 463 451 344 NA NA NA NA NA NA NA 31435 FUN_041525 432 310 349 393 515 NA NA NA NA NA NA NA 31436 FUN_041526 518 256 297 181 136 NA NA NA NA NA NA NA 31437 FUN_041520 108 45 134 110 207 NA NA NA NA NA NA NA 31438 FUN_041521 4457 2520 3467 5490 4420 ptg000035l:4693003-4731602 Q7SIB2 5.26e-55 Collagen alpha-1(IV) chain [Cleaved into: Arresten] Bos taurus (Bovine) basement membrane organization [GO:0071711]; brain development [GO:0007420]; branching involved in blood vessel morphogenesis [GO:0001569]; cellular response to amino acid stimulus [GO:0071230]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; extracellular matrix organization [GO:0030198]; neuromuscular junction development [GO:0007528]; renal tubule morphogenesis [GO:0061333]; retinal blood vessel morphogenesis [GO:0061304] GO:0001569; GO:0005201; GO:0005587; GO:0005604; GO:0005615; GO:0007420; GO:0007528; GO:0030020; GO:0030198; GO:0031012; GO:0038063; GO:0048407; GO:0061304; GO:0061333; GO:0071230; GO:0071711 31439 FUN_041521 4457 2520 3467 5490 4420 ptg000035l:4693003-4731602 Q7SIB2 5.49e-25 Collagen alpha-1(IV) chain [Cleaved into: Arresten] Bos taurus (Bovine) basement membrane organization [GO:0071711]; brain development [GO:0007420]; branching involved in blood vessel morphogenesis [GO:0001569]; cellular response to amino acid stimulus [GO:0071230]; collagen-activated tyrosine kinase receptor signaling pathway [GO:0038063]; extracellular matrix organization [GO:0030198]; neuromuscular junction development [GO:0007528]; renal tubule morphogenesis [GO:0061333]; retinal blood vessel morphogenesis [GO:0061304] GO:0001569; GO:0005201; GO:0005587; GO:0005604; GO:0005615; GO:0007420; GO:0007528; GO:0030020; GO:0030198; GO:0031012; GO:0038063; GO:0048407; GO:0061304; GO:0061333; GO:0071230; GO:0071711 31440 FUN_041522 3224 1748 1348 2292 1811 NA NA NA NA NA NA NA 31441 FUN_041523 1428 1237 475 1140 542 ptg000035l:4799859-4803216 P18700 3.56e-112 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 31442 FUN_041523 1428 1237 475 1140 542 ptg000035l:4799859-4803216 P18700 1.42e-53 Tubulin beta chain (Beta-tubulin) Strongylocentrotus purpuratus (Purple sea urchin) microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000278; GO:0003924; GO:0005200; GO:0005525; GO:0005737; GO:0005874 31443 FUN_041528 30 0 30 25 54 NA NA NA NA NA NA NA 31444 FUN_041529 0 4 0 0 84 NA NA NA NA NA NA NA 31445 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 4.33e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31446 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 9.12e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31447 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 1.07e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31448 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 1.8e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31449 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 2.79e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31450 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 2.02e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31451 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 2.02e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31452 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 3.15e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31453 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 4.76e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31454 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 1.01e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31455 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 2.19e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31456 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 3.02e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31457 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 1.53e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31458 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 6.19e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31459 FUN_033143 0 0 7 7 5 ptg000023l:40397608-40403664 Q80XJ3 1.81e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 31460 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 7.74e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31461 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 7.74e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31462 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 3.72e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31463 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 3.72e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31464 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 3.85e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31465 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 3.85e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31466 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 2.06e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31467 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 8.79e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31468 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 6.04e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31469 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 6.04e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31470 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 7.19e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31471 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 7.54e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31472 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 1.99e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31473 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 3.33e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31474 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 5.84e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31475 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 1.86e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31476 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 2.94e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31477 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 2.01e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31478 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 2.72e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31479 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 5.43e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31480 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 7.43e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31481 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 9.01e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31482 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 1.29e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31483 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 8.91e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31484 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 3.36e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31485 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 5.36e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31486 FUN_033142 0 0 1 17 5 ptg000023l:40395643-40397384 Q96AY4 6.14e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31487 FUN_033141 14 0 0 8 27 NA NA NA NA NA NA NA 31488 FUN_033147 0 49 0 0 9 NA NA NA NA NA NA NA 31489 FUN_033146 6 10 18 0 153 NA NA NA NA NA NA NA 31490 FUN_033145 145 55 307 428 547 ptg000023l:40418459-40423066 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31491 FUN_033145 145 55 307 428 547 ptg000023l:40418459-40423066 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31492 FUN_033145 145 55 307 428 547 ptg000023l:40418459-40423066 Q96AY4 8.11e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31493 FUN_033145 145 55 307 428 547 ptg000023l:40418459-40423066 Q96AY4 1.95e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31494 FUN_033145 145 55 307 428 547 ptg000023l:40418459-40423066 Q96AY4 8.85e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31495 FUN_033145 145 55 307 428 547 ptg000023l:40418459-40423066 Q96AY4 1.17e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31496 FUN_033144 0 0 0 2 22 NA NA NA NA NA NA NA 31497 FUN_028649 0 0 0 2 166 NA NA NA NA NA NA NA 31498 FUN_036871 36 21 19 56 14 NA NA NA NA NA NA NA 31499 FUN_035797 0 0 0 0 18 NA NA NA NA NA NA NA 31500 FUN_008849 20 35 2 18 10 NA NA NA NA NA NA NA 31501 FUN_030542 28 13 23 5 197 NA NA NA NA NA NA NA 31502 FUN_042958 1205 645 578 1075 857 ptg000047l:2407511-2432217 Q9EPE9 2.86e-22 Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Endoplasmic reticulum P5A-ATPase) Mus musculus (Mouse) cellular calcium ion homeostasis [GO:0006874]; extraction of mislocalized protein from ER membrane [GO:0140569]; protein transport [GO:0015031]; transmembrane transport [GO:0055085] GO:0005524; GO:0005789; GO:0006874; GO:0015031; GO:0015662; GO:0016020; GO:0016887; GO:0019829; GO:0046872; GO:0055085; GO:0140567; GO:0140569 31503 FUN_042959 680 902 798 923 804 NA NA NA NA NA NA NA 31504 FUN_042954 289 43 56 39 76 NA NA NA NA NA NA NA 31505 FUN_016675 14 11 34 70 22 ptg000011l:6195248-6200888 Q9NS40 2.38e-39 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (hERG-3) (Voltage-gated potassium channel subunit Kv11.3) Homo sapiens (Human) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005886; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 31506 FUN_016675 14 11 34 70 22 ptg000011l:6195248-6200888 Q9NS40 2.51e-24 Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3) (ERG-3) (Eag-related protein 3) (Ether-a-go-go-related protein 3) (hERG-3) (Voltage-gated potassium channel subunit Kv11.3) Homo sapiens (Human) circadian rhythm [GO:0007623]; membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005242; GO:0005249; GO:0005886; GO:0007623; GO:0034765; GO:0042391; GO:0044877; GO:0071805; GO:0086011 31507 FUN_016676 233 101 220 153 52 NA NA NA NA NA NA NA 31508 FUN_016677 60 26 57 245 52 ptg000011l:6210846-6214404 A2RUC4 4.73e-31 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 31509 FUN_016677 60 26 57 245 52 ptg000011l:6210846-6214404 A2RUC4 4.46e-22 tRNA wybutosine-synthesizing protein 5 (hTYW5) (tRNA yW-synthesizing protein 5) (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Homo sapiens (Human) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0005737; GO:0016706; GO:0031591; GO:0042803; GO:0102524 31510 FUN_016670 141 14 72 117 129 NA NA NA NA NA NA NA 31511 FUN_042951 2303 2869 2158 64 1721 NA NA NA NA NA NA NA 31512 FUN_016672 14 10 6 8 47 NA NA NA NA NA NA NA 31513 FUN_016673 17 0 0 19 0 ptg000011l:6186469-6187010 P59111 5.48e-29 Potassium voltage-gated channel subfamily H member 8 (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (Voltage-gated potassium channel subunit Kv12.1) Mus musculus (Mouse) negative regulation of apoptotic process [GO:0043066]; potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0000978; GO:0005249; GO:0005886; GO:0034765; GO:0042391; GO:0043066; GO:0071805 31514 FUN_006568 2490 1740 1627 2426 2550 NA NA NA NA NA NA NA 31515 FUN_035798 0 0 0 0 14 NA NA NA NA NA NA NA 31516 FUN_035799 4 0 0 0 36 NA NA NA NA NA NA NA 31517 FUN_010534 0 10 1 0 3 NA NA NA NA NA NA NA 31518 FUN_004894 2 2 28 9 10 NA NA NA NA NA NA NA 31519 FUN_010531 0 0 0 0 32 NA NA NA NA NA NA NA 31520 FUN_010533 112 0 0 370 23 NA NA NA NA NA NA NA 31521 FUN_010539 0 0 0 0 41 NA NA NA NA NA NA NA 31522 FUN_028545 17 0 0 0 23 NA NA NA NA NA NA NA 31523 FUN_041387 60 42 34 70 94 NA NA NA NA NA NA NA 31524 FUN_012009 615 398 221 233 262 NA NA NA NA NA NA NA 31525 FUN_012008 1174 1144 531 1405 592 ptg000008l:4011498-4020517 Q8BHD0 3.75e-42 Ras-related protein Rab-39A (Rab-39) Mus musculus (Mouse) autophagy [GO:0006914]; phagosome acidification [GO:0090383]; phagosome-lysosome fusion [GO:0090385]; protein transport [GO:0015031]; Rab protein signal transduction [GO:0032482]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0005525; GO:0005764; GO:0005794; GO:0005886; GO:0006914; GO:0015031; GO:0016192; GO:0030670; GO:0032482; GO:0045335; GO:0090383; GO:0090385 31526 FUN_012007 2743 1766 1081 393 453 NA NA NA NA NA NA NA 31527 FUN_012006 89 95 33 4 70 NA NA NA NA NA NA NA 31528 FUN_012004 535 377 133 374 187 NA NA NA NA NA NA NA 31529 FUN_012003 386 205 159 223 459 NA NA NA NA NA NA NA 31530 FUN_012002 74 140 50 71 17 NA NA NA NA NA NA NA 31531 FUN_012001 3947 2321 2256 3504 3445 NA NA NA NA NA NA NA 31532 FUN_028541 0 0 0 0 32 NA NA NA NA NA NA NA 31533 FUN_020907 0 0 0 0 6 NA NA NA NA NA NA NA 31534 FUN_020906 9 2 32 0 5 NA NA NA NA NA NA NA 31535 FUN_020904 44 0 0 0 0 NA NA NA NA NA NA NA 31536 FUN_020903 144 0 52 0 0 NA NA NA NA NA NA NA 31537 FUN_031495 1249 425 549 847 1238 NA NA NA NA NA NA NA 31538 FUN_020901 3 0 0 0 28 NA NA NA NA NA NA NA 31539 FUN_031494 1137 641 563 1190 821 NA NA NA NA NA NA NA 31540 FUN_020909 8 0 22 11 82 NA NA NA NA NA NA NA 31541 FUN_020908 2 0 16 9 18 NA NA NA NA NA NA NA 31542 FUN_011662 53 167 61 166 421 NA NA NA NA NA NA NA 31543 FUN_011660 5 4 18 0 128 NA NA NA NA NA NA NA 31544 FUN_011661 3 15 10 13 32 NA NA NA NA NA NA NA 31545 FUN_014522 394 345 299 312 292 NA NA NA NA NA NA NA 31546 FUN_014523 614 476 352 267 401 NA NA NA NA NA NA NA 31547 FUN_014520 0 0 20 3 11 NA NA NA NA NA NA NA 31548 FUN_014521 0 0 9 0 18 NA NA NA NA NA NA NA 31549 FUN_013759 18 0 0 0 0 NA NA NA NA NA NA NA 31550 FUN_014524 22743 24919 10239 20534 20037 ptg000009l:918626-921821 P60868 3.52e-28 40S ribosomal protein S20 Rattus norvegicus (Rat) positive regulation of signal transduction by p53 class mediator [GO:1901798]; translation [GO:0006412] GO:0003723; GO:0003735; GO:0006412; GO:0015935; GO:0022626; GO:0022627; GO:0045202; GO:0097371; GO:1901798; GO:1990948 31551 FUN_014525 4858 2596 2719 3965 2979 ptg000009l:925390-940851 Q7PPA5 1.31e-37 Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 7.2.2.10) (Calcium pump) (Sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase) Anopheles gambiae (African malaria mosquito) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220] GO:0005388; GO:0005524; GO:0006874; GO:0015662; GO:0016020; GO:0016887; GO:0033017; GO:0034220; GO:0046872; GO:0070588 31552 FUN_014525 4858 2596 2719 3965 2979 ptg000009l:925390-940851 Q7PPA5 9.39e-28 Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type (EC 7.2.2.10) (Calcium pump) (Sarcoplasmic/endoplasmic reticulum Ca(2+)-ATPase) Anopheles gambiae (African malaria mosquito) calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; ion transmembrane transport [GO:0034220] GO:0005388; GO:0005524; GO:0006874; GO:0015662; GO:0016020; GO:0016887; GO:0033017; GO:0034220; GO:0046872; GO:0070588 31553 FUN_013754 0 0 3 8 0 NA NA NA NA NA NA NA 31554 FUN_023284 0 0 84 59 71 NA NA NA NA NA NA NA 31555 FUN_014529 2697 1613 798 1259 913 NA NA NA NA NA NA NA 31556 FUN_023281 63 158 29 93 0 ptg000017l:5896869-5898658 A0A2B4SJA1 1.46e-96 NA NA NA NA 31557 FUN_023283 0 0 6 9 5 NA NA NA NA NA NA NA 31558 FUN_022888 1760 2145 784 982 397 NA NA NA NA NA NA NA 31559 FUN_022889 94 56 48 58 64 NA NA NA NA NA NA NA 31560 FUN_009409 0 0 14 39 60 NA NA NA NA NA NA NA 31561 FUN_009408 12 1 11 0 72 NA NA NA NA NA NA NA 31562 FUN_022880 0 0 0 0 18 NA NA NA NA NA NA NA 31563 FUN_009406 0 0 6 0 0 NA NA NA NA NA NA NA 31564 FUN_009405 0 0 8 0 45 NA NA NA NA NA NA NA 31565 FUN_009404 0 7 0 0 0 ptg000004l:6457132-6461141 B8VIU6 5.02e-34 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 31566 FUN_022886 6 0 0 970 987 ptg000017l:1112289-1136302 Q9P2E3 1.02e-70 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31567 FUN_022886 6 0 0 970 987 ptg000017l:1112289-1136302 Q9P2E3 5.46e-45 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31568 FUN_022886 6 0 0 970 987 ptg000017l:1112289-1136302 Q9P2E3 1.53e-40 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31569 FUN_022886 6 0 0 970 987 ptg000017l:1112289-1136302 Q9P2E3 1.4e-39 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31570 FUN_022887 141 172 154 367 1173 ptg000017l:1136446-1157683 Q9P2E3 6.47e-62 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31571 FUN_022887 141 172 154 367 1173 ptg000017l:1136446-1157683 Q9P2E3 1.79e-39 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31572 FUN_022887 141 172 154 367 1173 ptg000017l:1136446-1157683 Q9P2E3 2.87e-29 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31573 FUN_022887 141 172 154 367 1173 ptg000017l:1136446-1157683 Q9P2E3 2.83e-26 NFX1-type zinc finger-containing protein 1 Homo sapiens (Human) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 31574 FUN_029708 546 376 220 484 401 NA NA NA NA NA NA NA 31575 FUN_029709 857 1070 310 581 650 NA NA NA NA NA NA NA 31576 FUN_029702 88 0 28 0 6 ptg000023l:4688490-4690230 F6QEU4 3.44e-36 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 31577 FUN_029703 50 13 39 15 502 NA NA NA NA NA NA NA 31578 FUN_029706 185 436 54 148 123 ptg000023l:4766474-4766930 Q90YI8 3.94e-27 T-cell acute lymphocytic leukemia protein 1 (TAL-1) (FrSCL) (Stem cell protein) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) angiogenesis [GO:0001525]; artery morphogenesis [GO:0048844]; definitive hemopoiesis [GO:0060216]; endocardium formation [GO:0060214]; erythrocyte differentiation [GO:0030218]; hemangioblast cell differentiation [GO:0060217]; hematopoietic stem cell differentiation [GO:0060218]; myeloid cell differentiation [GO:0030099]; primitive hemopoiesis [GO:0060215]; vasculogenesis [GO:0001570] GO:0000981; GO:0001525; GO:0001570; GO:0003677; GO:0005634; GO:0030099; GO:0030218; GO:0046983; GO:0048844; GO:0060214; GO:0060215; GO:0060216; GO:0060217; GO:0060218 31579 FUN_029707 47 282 47 93 310 ptg000023l:4774023-4781623 E7FAM5 4.7e-48 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 31580 FUN_029707 47 282 47 93 310 ptg000023l:4774023-4781623 E7FAM5 3.6e-30 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 31581 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 4.68e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31582 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 5.71e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31583 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 4.08e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31584 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 2.11e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31585 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 1.67e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31586 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 4.45e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31587 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 2.15e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31588 FUN_029704 118 66 81 8 0 ptg000023l:4709092-4715333 Q96AY4 1.05e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31589 FUN_029705 42 42 4 14 87 ptg000023l:4754182-4756345 E7FAM5 5e-56 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 31590 FUN_023429 16 11 23 34 9 NA NA NA NA NA NA NA 31591 FUN_011188 28 0 44 8 191 NA NA NA NA NA NA NA 31592 FUN_026419 31 33 43 79 141 NA NA NA NA NA NA NA 31593 FUN_026418 169 66 161 117 87 NA NA NA NA NA NA NA 31594 FUN_023421 940 746 508 710 587 NA NA NA NA NA NA NA 31595 FUN_026416 1759 804 772 3802 2489 NA NA NA NA NA NA NA 31596 FUN_026415 935 430 564 1149 990 ptg000020l:8532821-8544949 Q9UHI7 5.64e-29 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 31597 FUN_026414 364 225 240 614 221 ptg000020l:8515154-8527751 Q9UHI7 1.33e-28 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 31598 FUN_026413 30941 25415 14299 22457 21258 NA NA NA NA NA NA NA 31599 FUN_023424 0 0 4 16 316 NA NA NA NA NA NA NA 31600 FUN_026411 1513 2102 1073 647 772 NA NA NA NA NA NA NA 31601 FUN_023426 2527 1562 1298 1649 1245 ptg000017l:7382382-7390981 Q9H8M5 3.58e-131 Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2) Homo sapiens (Human) magnesium ion homeostasis [GO:0010960] GO:0005524; GO:0005886; GO:0010960; GO:0015095; GO:0016323; GO:0022857; GO:0043231 31602 FUN_039958 275 125 6 72 24 ptg000031l:2089403-2093538 Q96AY4 1.18e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31603 FUN_039958 275 125 6 72 24 ptg000031l:2089403-2093538 Q96AY4 5.82e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31604 FUN_039958 275 125 6 72 24 ptg000031l:2089403-2093538 Q96AY4 1.1e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31605 FUN_039958 275 125 6 72 24 ptg000031l:2089403-2093538 Q96AY4 3.52e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31606 FUN_039958 275 125 6 72 24 ptg000031l:2089403-2093538 Q96AY4 7.93e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31607 FUN_039956 459 0 0 0 0 NA NA NA NA NA NA NA 31608 FUN_039957 132 11 0 20 23 ptg000031l:2070199-2074212 Q96AY4 3.6e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31609 FUN_039957 132 11 0 20 23 ptg000031l:2070199-2074212 Q96AY4 1.81e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31610 FUN_039957 132 11 0 20 23 ptg000031l:2070199-2074212 Q96AY4 4.33e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31611 FUN_039957 132 11 0 20 23 ptg000031l:2070199-2074212 Q96AY4 1.02e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31612 FUN_039954 565 221 221 237 81 ptg000031l:2052657-2056959 Q96AY4 1.24e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31613 FUN_039954 565 221 221 237 81 ptg000031l:2052657-2056959 Q96AY4 5.06e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31614 FUN_039954 565 221 221 237 81 ptg000031l:2052657-2056959 Q96AY4 4.61e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31615 FUN_039954 565 221 221 237 81 ptg000031l:2052657-2056959 Q96AY4 2.28e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31616 FUN_039954 565 221 221 237 81 ptg000031l:2052657-2056959 Q96AY4 3.16e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31617 FUN_039954 565 221 221 237 81 ptg000031l:2052657-2056959 Q96AY4 3.94e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31618 FUN_039955 118 0 0 0 0 NA NA NA NA NA NA NA 31619 FUN_039952 3 9 12 24 1 NA NA NA NA NA NA NA 31620 FUN_039953 1886 0 6 3 0 NA NA NA NA NA NA NA 31621 FUN_039950 53 0 11 24 0 NA NA NA NA NA NA NA 31622 FUN_039951 627 1054 367 501 220 NA NA NA NA NA NA NA 31623 FUN_015693 0 0 7 0 39 NA NA NA NA NA NA NA 31624 FUN_015692 21 5 0 15 38 NA NA NA NA NA NA NA 31625 FUN_015691 0 51 77 14 56 NA NA NA NA NA NA NA 31626 FUN_015690 3 22 76 10 116 NA NA NA NA NA NA NA 31627 FUN_015697 0 0 0 6 40 NA NA NA NA NA NA NA 31628 FUN_015696 14 0 0 0 0 NA NA NA NA NA NA NA 31629 FUN_005790 0 0 6 1 16 NA NA NA NA NA NA NA 31630 FUN_015345 445 277 169 370 149 NA NA NA NA NA NA NA 31631 FUN_015344 914 1006 615 829 713 NA NA NA NA NA NA NA 31632 FUN_015347 633 392 152 489 427 NA NA NA NA NA NA NA 31633 FUN_015346 1600 2411 1398 1750 1709 NA NA NA NA NA NA NA 31634 FUN_015341 30 16 3 0 0 NA NA NA NA NA NA NA 31635 FUN_015340 14789 10738 6039 11737 12125 NA NA NA NA NA NA NA 31636 FUN_018528 964 1315 510 715 971 ptg000012l:10444440-10469918 Q96RW7 6.46e-71 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 31637 FUN_018528 964 1315 510 715 971 ptg000012l:10444440-10469918 Q96RW7 3.13e-65 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 31638 FUN_018528 964 1315 510 715 971 ptg000012l:10444440-10469918 Q96RW7 9.73e-63 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 31639 FUN_015342 19 40 16 68 61 NA NA NA NA NA NA NA 31640 FUN_018526 1211 941 473 1115 830 NA NA NA NA NA NA NA 31641 FUN_018527 2054 1247 459 517 531 NA NA NA NA NA NA NA 31642 FUN_018524 29 60 0 20 45 NA NA NA NA NA NA NA 31643 FUN_018525 826 763 289 908 380 NA NA NA NA NA NA NA 31644 FUN_015349 74 40 31 74 58 NA NA NA NA NA NA NA 31645 FUN_015348 237 163 91 94 174 NA NA NA NA NA NA NA 31646 FUN_018520 747 574 537 736 1092 NA NA NA NA NA NA NA 31647 FUN_018521 1166 631 422 787 951 ptg000012l:10383994-10385785 O95453 2.13e-172 Poly(A)-specific ribonuclease PARN (EC 3.1.13.4) (Deadenylating nuclease) (Deadenylation nuclease) (Polyadenylate-specific ribonuclease) Homo sapiens (Human) box H/ACA RNA 3'-end processing [GO:0000495]; female gamete generation [GO:0007292]; miRNA catabolic process [GO:0010587]; ncRNA deadenylation [GO:0110008]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of telomerase RNA localization to Cajal body [GO:1904872]; RNA modification [GO:0009451]; RNA phosphodiester bond hydrolysis, exonucleolytic [GO:0090503]; telomerase RNA stabilization [GO:0090669] GO:0000175; GO:0000184; GO:0000289; GO:0000495; GO:0003723; GO:0003730; GO:0004518; GO:0004535; GO:0005634; GO:0005730; GO:0005737; GO:0005829; GO:0007292; GO:0009451; GO:0010587; GO:0016607; GO:0019901; GO:0032212; GO:0043169; GO:0046872; GO:0051973; GO:0070034; GO:0071051; GO:0090503; GO:0090669; GO:0110008; GO:1904872 31648 FUN_001484 1761 1643 891 1343 1001 NA NA NA NA NA NA NA 31649 FUN_032661 7 14 33 0 0 NA NA NA NA NA NA NA 31650 FUN_025148 0 0 0 0 51 ptg000018l:14498939-14504578 P14381 1.81e-68 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 31651 FUN_025148 0 0 0 0 51 ptg000018l:14498939-14504578 P14381 1.81e-68 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 31652 FUN_025148 0 0 0 0 51 ptg000018l:14498939-14504578 P14381 2.01e-24 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 31653 FUN_025144 782 653 288 902 763 NA NA NA NA NA NA NA 31654 FUN_025147 10 0 3 0 50 NA NA NA NA NA NA NA 31655 FUN_025140 2545 2365 1359 2348 1832 NA NA NA NA NA NA NA 31656 FUN_025141 0 0 4 0 45 NA NA NA NA NA NA NA 31657 FUN_025142 0 0 0 48 16 NA NA NA NA NA NA NA 31658 FUN_025143 15 23 0 0 0 NA NA NA NA NA NA NA 31659 FUN_028524 437 284 24 653 296 NA NA NA NA NA NA NA 31660 FUN_024811 39 121 13 99 259 NA NA NA NA NA NA NA 31661 FUN_024810 0 0 0 0 23 NA NA NA NA NA NA NA 31662 FUN_024813 6071 3016 2651 4979 2949 NA NA NA NA NA NA NA 31663 FUN_024812 0 46 21 52 198 NA NA NA NA NA NA NA 31664 FUN_024815 4179 2400 2256 5546 3770 ptg000018l:11374988-11395390 Q80U35 2.4e-29 Rho guanine nucleotide exchange factor 17 Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036] GO:0005085; GO:0030036 31665 FUN_024814 11924 9459 6043 12105 7182 ptg000018l:11350744-11370517 A2A259 3.4e-30 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to pH [GO:0071467]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0034703; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051262; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071467; GO:0071468; GO:0071805; GO:0097730; GO:0098662 31666 FUN_024817 10 0 0 184 168 NA NA NA NA NA NA NA 31667 FUN_024816 0 0 0 21 0 NA NA NA NA NA NA NA 31668 FUN_024819 15 0 0 0 14 NA NA NA NA NA NA NA 31669 FUN_038331 57 1 15 8 116 NA NA NA NA NA NA NA 31670 FUN_038330 1717 969 610 1170 1279 NA NA NA NA NA NA NA 31671 FUN_038333 399 295 250 232 493 NA NA NA NA NA NA NA 31672 FUN_038332 4631 3354 2731 11377 6700 ptg000027l:5815729-5821155 Q8IWB9 1.73e-32 Testis-expressed protein 2 (Transmembrane protein 96) Homo sapiens (Human) lipid transport [GO:0006869]; signal transduction [GO:0007165]; sphingolipid metabolic process [GO:0006665] GO:0005783; GO:0005789; GO:0006665; GO:0006869; GO:0007165; GO:0008289; GO:0016020; GO:0031965 31673 FUN_038335 2968 2218 2115 1948 1680 NA NA NA NA NA NA NA 31674 FUN_038334 1162 1110 432 1251 866 ptg000027l:5830436-5833805 Q6AYK1 8.94e-25 RNA-binding protein with serine-rich domain 1 Rattus norvegicus (Rat) mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of apoptotic process [GO:0043065]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381] GO:0000184; GO:0000381; GO:0000398; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0016607; GO:0043065; GO:0048025; GO:0061574 31675 FUN_038337 2873 2745 1488 4207 2963 NA NA NA NA NA NA NA 31676 FUN_038336 1899 1687 1354 1393 1105 ptg000027l:5839729-5841251 Q04841 7.31e-37 DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase) Mus musculus (Mouse) base-excision repair [GO:0006284] GO:0003677; GO:0003905; GO:0005654; GO:0005829; GO:0006284; GO:0008725; GO:0042645; GO:0043916; GO:0052821; GO:0052822 31677 FUN_038339 17715 15692 9389 12296 10324 ptg000027l:5888288-5892175 Q4R4J0 2.03e-22 Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Rho protein signal transduction [GO:0007266]; semaphorin-plexin signaling pathway [GO:0071526] GO:0005094; GO:0005096; GO:0005737; GO:0007266; GO:0071526 31678 FUN_038338 602 379 301 897 500 ptg000027l:5879026-5883228 Q8C0Q3 3.51e-25 Tetratricopeptide repeat protein 34 (TPR repeat protein 34) Mus musculus (Mouse) NA NA 31679 FUN_031817 71 25 0 0 12 NA NA NA NA NA NA NA 31680 FUN_031816 261 48 562 102 254 NA NA NA NA NA NA NA 31681 FUN_031815 12 3 55 18 62 NA NA NA NA NA NA NA 31682 FUN_031814 51 65 220 0 149 NA NA NA NA NA NA NA 31683 FUN_031819 215 138 127 459 207 NA NA NA NA NA NA NA 31684 FUN_031818 4 16 0 0 17 NA NA NA NA NA NA NA 31685 FUN_006876 49 0 42 20 207 NA NA NA NA NA NA NA 31686 FUN_019694 5 0 81 0 126 NA NA NA NA NA NA NA 31687 FUN_019693 18 0 101 0 212 NA NA NA NA NA NA NA 31688 FUN_019691 0 0 17 0 7 NA NA NA NA NA NA NA 31689 FUN_043175 1747 937 594 1822 1237 NA NA NA NA NA NA NA 31690 FUN_043174 362 554 370 464 470 NA NA NA NA NA NA NA 31691 FUN_043177 13 21 8 7 10 NA NA NA NA NA NA NA 31692 FUN_044273 81 32 50 44 61 NA NA NA NA NA NA NA 31693 FUN_044272 3 2 26 8 118 NA NA NA NA NA NA NA 31694 FUN_030140 0 0 18 0 7 NA NA NA NA NA NA NA 31695 FUN_035313 540 258 302 301 485 ptg000025l:6330547-6331846 A0A3M6TIF0 0 NA NA NA NA 31696 FUN_035315 18 42 12 10 0 NA NA NA NA NA NA NA 31697 FUN_044275 184 76 117 48 112 ptg000132l:2548-8327 O54853 1.25e-29 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 31698 FUN_044275 184 76 117 48 112 ptg000132l:2548-8327 O54853 1.25e-28 Potassium voltage-gated channel subfamily H member 6 (Ether-a-go-go-related gene potassium channel 2) (ERG-2) (Eag-related protein 2) (Ether-a-go-go-related protein 2) (Voltage-gated potassium channel subunit Kv11.2) Rattus norvegicus (Rat) membrane repolarization during action potential [GO:0086011]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307] GO:0005242; GO:0005249; GO:0005267; GO:0005886; GO:0006813; GO:0034765; GO:0042391; GO:0044877; GO:0060307; GO:0071805; GO:0086011; GO:0086091 31699 FUN_035318 32 7 8 16 14 NA NA NA NA NA NA NA 31700 FUN_035319 16 30 0 11 24 NA NA NA NA NA NA NA 31701 FUN_030148 0 0 0 0 12 NA NA NA NA NA NA NA 31702 FUN_000979 20 4 0 21 128 NA NA NA NA NA NA NA 31703 FUN_036662 19 0 22 0 43 NA NA NA NA NA NA NA 31704 FUN_036664 0 0 0 0 6 NA NA NA NA NA NA NA 31705 FUN_036666 80 6 0 0 7 NA NA NA NA NA NA NA 31706 FUN_001954 3938 4887 2390 5131 2806 NA NA NA NA NA NA NA 31707 FUN_001957 1319 1137 840 903 1048 NA NA NA NA NA NA NA 31708 FUN_001956 2436 2333 1251 2272 1721 NA NA NA NA NA NA NA 31709 FUN_001950 1759 1282 1016 2103 1606 ntLink_6:18205280-18224347 P23508 6.13e-57 Colorectal mutant cancer protein (Protein MCC) Homo sapiens (Human) establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0010633; GO:0016055; GO:0030027; GO:0036464; GO:0038023; GO:0045184; GO:0050680; GO:0090090 31710 FUN_001950 1759 1282 1016 2103 1606 ntLink_6:18205280-18224347 P23508 1.43e-22 Colorectal mutant cancer protein (Protein MCC) Homo sapiens (Human) establishment of protein localization [GO:0045184]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of epithelial cell migration [GO:0010633]; negative regulation of epithelial cell proliferation [GO:0050680]; signal transduction [GO:0007165]; Wnt signaling pathway [GO:0016055] GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0010633; GO:0016055; GO:0030027; GO:0036464; GO:0038023; GO:0045184; GO:0050680; GO:0090090 31711 FUN_001953 117 0 71 142 102 NA NA NA NA NA NA NA 31712 FUN_001952 4093 1417 1577 3311 1969 NA NA NA NA NA NA NA 31713 FUN_028978 118 149 74 173 240 NA NA NA NA NA NA NA 31714 FUN_011458 0 0 0 10 0 NA NA NA NA NA NA NA 31715 FUN_030494 118 7 10 20 640 ptg000023l:10996359-10997631 P35061 1.66e-81 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31716 FUN_030495 12 1 12 0 65 ptg000023l:10997963-11000397 P84239 2.21e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31717 FUN_030496 12 0 9 2 66 ptg000023l:11002018-11004446 P84239 2.13e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31718 FUN_030497 9 2 7 2 63 ptg000023l:11006067-11008495 P84239 2.13e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31719 FUN_030490 6 0 10 1 43 ptg000023l:10986918-10987681 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31720 FUN_030491 12 0 32 0 32 ptg000023l:10988274-10989547 P35061 1.66e-81 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31721 FUN_030492 5 0 3 1 27 ptg000023l:10989879-10992309 P84239 1.59e-84 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31722 FUN_030498 10 2 7 2 60 ptg000023l:11010116-11012544 P84239 2.13e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31723 FUN_030499 12 0 7 0 71 ptg000023l:11014165-11016593 P84239 2.13e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31724 FUN_039178 0 7 0 0 0 NA NA NA NA NA NA NA 31725 FUN_031364 0 34 0 0 19 ptg000023l:20127425-20128036 Q6ITT3 8.01e-26 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 31726 FUN_031364 0 34 0 0 19 ptg000023l:20127425-20128036 Q6ITT3 8.01e-26 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Sus scrofa (Pig) protein N-linked glycosylation [GO:0006487] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0046872 31727 FUN_031361 0 11 0 0 0 NA NA NA NA NA NA NA 31728 FUN_031360 0 19 0 0 8 NA NA NA NA NA NA NA 31729 FUN_031362 26 43 35 0 65 ptg000023l:20099514-20112333 Q5DU56 6.15e-45 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31730 FUN_031362 26 43 35 0 65 ptg000023l:20099514-20112333 Q5DU56 6.64e-39 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31731 FUN_031362 26 43 35 0 65 ptg000023l:20099514-20112333 Q5DU56 5.32e-36 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31732 FUN_031362 26 43 35 0 65 ptg000023l:20099514-20112333 Q5DU56 2.6e-33 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31733 FUN_031362 26 43 35 0 65 ptg000023l:20099514-20112333 Q5DU56 1.26e-31 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31734 FUN_031362 26 43 35 0 65 ptg000023l:20099514-20112333 Q5DU56 1.48e-24 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31735 FUN_039172 0 0 0 0 8 NA NA NA NA NA NA NA 31736 FUN_031369 1260 782 759 24 668 NA NA NA NA NA NA NA 31737 FUN_031368 26 0 46 0 74 NA NA NA NA NA NA NA 31738 FUN_027731 175 7 8 122 338 NA NA NA NA NA NA NA 31739 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 1.87e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31740 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 3.85e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31741 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 8.43e-72 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31742 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 9.88e-71 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31743 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 1.01e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31744 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 1.45e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31745 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 1.33e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31746 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 3.64e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31747 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 1.32e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31748 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 1.72e-47 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31749 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 5.19e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31750 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 6.4e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31751 FUN_027730 11 0 0 7 0 ptg000021l:9759126-9763772 Q7RTR2 5.37e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 31752 FUN_027732 140 0 0 47 170 NA NA NA NA NA NA NA 31753 FUN_027735 923 565 503 628 537 NA NA NA NA NA NA NA 31754 FUN_027734 1081 876 478 2365 2656 NA NA NA NA NA NA NA 31755 FUN_027736 2611 1764 1219 2103 2282 NA NA NA NA NA NA NA 31756 FUN_014795 522 725 819 348 225 NA NA NA NA NA NA NA 31757 FUN_014794 2004 1296 1154 1328 1148 NA NA NA NA NA NA NA 31758 FUN_014797 901 1102 842 966 537 ptg000009l:3190433-3197272 Q91WC1 1.81e-40 Protection of telomeres protein 1 (mPot1) (POT1-like telomere end-binding protein) Mus musculus (Mouse) chromosome organization [GO:0051276]; DNA duplex unwinding [GO:0032508]; establishment of protein localization to telomere [GO:0070200]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; positive regulation of DNA helicase activity [GO:1905776]; positive regulation of DNA strand elongation [GO:0060383]; positive regulation of helicase activity [GO:0051096]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere maintenance [GO:0032206]; positive regulation of telomere maintenance via telomerase [GO:0032212]; regulation of DNA helicase activity [GO:1905774]; regulation of double-strand break repair via nonhomologous end joining [GO:2001032]; regulation of telomere maintenance via telomerase [GO:0032210]; telomere assembly [GO:0032202]; telomere capping [GO:0016233]; telomere maintenance via telomerase [GO:0007004]; telomeric D-loop disassembly [GO:0061820] GO:0000781; GO:0000783; GO:0005654; GO:0007004; GO:0010521; GO:0016233; GO:0017151; GO:0032202; GO:0032206; GO:0032210; GO:0032211; GO:0032212; GO:0032508; GO:0042162; GO:0043047; GO:0051096; GO:0051276; GO:0051973; GO:0051974; GO:0060383; GO:0061820; GO:0061821; GO:0070187; GO:0070200; GO:0098505; GO:1905773; GO:1905774; GO:1905776; GO:1990955; GO:2001032 31759 FUN_014796 1942 1078 415 1251 1112 NA NA NA NA NA NA NA 31760 FUN_013162 56 25 52 666 127 NA NA NA NA NA NA NA 31761 FUN_013161 4607 4103 2283 3961 2581 NA NA NA NA NA NA NA 31762 FUN_014792 418 470 188 447 419 NA NA NA NA NA NA NA 31763 FUN_036266 6 1 8 4 1 NA NA NA NA NA NA NA 31764 FUN_037208 3816 2218 1342 2396 1096 NA NA NA NA NA NA NA 31765 FUN_037209 0 0 0 0 22 NA NA NA NA NA NA NA 31766 FUN_037200 1540 1640 666 2101 2296 ptg000026l:7000847-7010892 L7YAI7 2.92e-21 Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1) Danio rerio (Zebrafish) (Brachydanio rerio) protein glycosylation [GO:0006486]; protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0006486; GO:0015020; GO:0035269; GO:0046872 31767 FUN_037201 53 44 40 27 27 NA NA NA NA NA NA NA 31768 FUN_037202 84 90 128 190 0 NA NA NA NA NA NA NA 31769 FUN_037203 10 2 1 13 21 NA NA NA NA NA NA NA 31770 FUN_037204 633 755 358 615 231 ptg000026l:7029537-7038085 P0CT43 4.97e-69 Transposon Tf2-8 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 31771 FUN_037205 1292 528 714 983 683 ptg000026l:7038286-7047040 Q0P5L8 2.31e-24 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase) Bos taurus (Bovine) biosynthetic process [GO:0009058]; L-threonine catabolic process to glycine [GO:0019518] GO:0005634; GO:0005739; GO:0008890; GO:0009058; GO:0019518; GO:0030170 31772 FUN_037206 947 906 557 788 842 NA NA NA NA NA NA NA 31773 FUN_037207 10 29 14 38 67 NA NA NA NA NA NA NA 31774 FUN_006729 3777 5307 4124 8886 5479 NA NA NA NA NA NA NA 31775 FUN_006728 2325 2242 1383 2109 1808 NA NA NA NA NA NA NA 31776 FUN_028405 0 21 0 11 13 NA NA NA NA NA NA NA 31777 FUN_006723 547 105 255 452 486 NA NA NA NA NA NA NA 31778 FUN_006721 212 109 114 224 154 NA NA NA NA NA NA NA 31779 FUN_006720 794 683 482 604 783 NA NA NA NA NA NA NA 31780 FUN_006727 1914 1131 1182 1997 1467 NA NA NA NA NA NA NA 31781 FUN_006726 483 540 145 273 182 ptg000001l:15937776-15939905 P83852 3.27e-121 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 31782 FUN_006725 611 568 202 367 468 NA NA NA NA NA NA NA 31783 FUN_006724 2 1 23 0 0 NA NA NA NA NA NA NA 31784 FUN_028973 258 242 100 125 100 NA NA NA NA NA NA NA 31785 FUN_039365 524 114 305 348 507 NA NA NA NA NA NA NA 31786 FUN_018336 19 7 144 60 25 NA NA NA NA NA NA NA 31787 FUN_039366 1489 458 554 1831 565 NA NA NA NA NA NA NA 31788 FUN_028970 11191 12003 7629 17030 14417 ptg000022l:6556492-6564458 P13195 5.89e-44 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1) Rattus norvegicus (Rat) cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; hemoglobin biosynthetic process [GO:0042541]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to bile acid [GO:1903412]; response to cAMP [GO:0051591]; response to cobalt ion [GO:0032025]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to nickel cation [GO:0010045]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to platinum ion [GO:0070541]; response to xenobiotic stimulus [GO:0009410] GO:0001666; GO:0003870; GO:0005739; GO:0005743; GO:0005759; GO:0006782; GO:0006783; GO:0009410; GO:0009635; GO:0010033; GO:0010045; GO:0014070; GO:0030170; GO:0031667; GO:0032025; GO:0032869; GO:0034698; GO:0042541; GO:0042802; GO:0045471; GO:0048821; GO:0051591; GO:0070541; GO:0071407; GO:1903412 31789 FUN_028970 11191 12003 7629 17030 14417 ptg000022l:6556492-6564458 P13195 1.19e-36 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1) Rattus norvegicus (Rat) cellular response to insulin stimulus [GO:0032869]; cellular response to organic cyclic compound [GO:0071407]; erythrocyte development [GO:0048821]; heme biosynthetic process [GO:0006783]; hemoglobin biosynthetic process [GO:0042541]; protoporphyrinogen IX biosynthetic process [GO:0006782]; response to bile acid [GO:1903412]; response to cAMP [GO:0051591]; response to cobalt ion [GO:0032025]; response to ethanol [GO:0045471]; response to gonadotropin [GO:0034698]; response to herbicide [GO:0009635]; response to hypoxia [GO:0001666]; response to nickel cation [GO:0010045]; response to nutrient levels [GO:0031667]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to platinum ion [GO:0070541]; response to xenobiotic stimulus [GO:0009410] GO:0001666; GO:0003870; GO:0005739; GO:0005743; GO:0005759; GO:0006782; GO:0006783; GO:0009410; GO:0009635; GO:0010033; GO:0010045; GO:0014070; GO:0030170; GO:0031667; GO:0032025; GO:0032869; GO:0034698; GO:0042541; GO:0042802; GO:0045471; GO:0048821; GO:0051591; GO:0070541; GO:0071407; GO:1903412 31790 FUN_012140 24 67 56 30 25 NA NA NA NA NA NA NA 31791 FUN_028976 880 1553 599 642 600 NA NA NA NA NA NA NA 31792 FUN_037795 1282 389 338 975 720 NA NA NA NA NA NA NA 31793 FUN_024300 30 4 4 0 3 ptg000018l:4536497-4540765 Q8K3Z0 3.55e-28 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 31794 FUN_001961 4 2979 337 243 7 NA NA NA NA NA NA NA 31795 FUN_038749 0 0 10 0 0 NA NA NA NA NA NA NA 31796 FUN_004479 8 29 4 10 3 NA NA NA NA NA NA NA 31797 FUN_004478 8 0 4 0 50 NA NA NA NA NA NA NA 31798 FUN_004475 585 374 360 513 291 NA NA NA NA NA NA NA 31799 FUN_004474 8217 7734 5259 9895 6390 NA NA NA NA NA NA NA 31800 FUN_004477 7520 8078 4655 6080 7265 NA NA NA NA NA NA NA 31801 FUN_004476 1739 965 622 1274 1517 NA NA NA NA NA NA NA 31802 FUN_004471 549 221 208 249 329 ntLink_8:23539362-23539965 Q86X83 7.13e-70 COMM domain-containing protein 2 Homo sapiens (Human) NA GO:0005737 31803 FUN_004470 46 52 46 45 121 ntLink_8:23538143-23539315 P0C872 1.28e-130 Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7 (EC 1.14.11.63) (EC 3.4.-.-) (JmjC domain-containing protein 7) (Jumonji domain-containing protein 7) (L-lysine (3S)-hydroxylase Jmjd7) Mus musculus (Mouse) protein hydroxylation [GO:0018126]; proteolysis [GO:0006508] GO:0004175; GO:0004177; GO:0004497; GO:0005634; GO:0005737; GO:0006508; GO:0016706; GO:0018126; GO:0035064; GO:0046872; GO:0106155 31804 FUN_004473 2230 1498 1160 1400 909 NA NA NA NA NA NA NA 31805 FUN_004472 106 63 91 136 139 ntLink_8:23541159-23543079 Q13042 0 Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (CDC16 homolog) (CDC16Hs) (Cyclosome subunit 6) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567]; regulation of meiotic cell cycle [GO:0051445]; regulation of mitotic cell cycle [GO:0007346] GO:0005654; GO:0005680; GO:0005737; GO:0005813; GO:0005829; GO:0007091; GO:0007346; GO:0016567; GO:0031145; GO:0045842; GO:0051301; GO:0051445; GO:0070979; GO:0072686 31806 FUN_002730 40 19 0 51 23 NA NA NA NA NA NA NA 31807 FUN_002732 71 41 0 97 26 NA NA NA NA NA NA NA 31808 FUN_002734 342 318 310 508 13 NA NA NA NA NA NA NA 31809 FUN_002735 3256 1557 4057 5333 659 NA NA NA NA NA NA NA 31810 FUN_002736 953 503 428 982 842 ntLink_8:5836685-5864114 Q99315 8.57e-70 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 31811 FUN_002736 953 503 428 982 842 ntLink_8:5836685-5864114 Q99315 8.57e-70 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 31812 FUN_002737 1788 1889 801 888 1231 NA NA NA NA NA NA NA 31813 FUN_002739 234 191 12 43 29 NA NA NA NA NA NA NA 31814 FUN_007928 690 460 322 863 869 NA NA NA NA NA NA NA 31815 FUN_007929 497 274 276 281 262 NA NA NA NA NA NA NA 31816 FUN_001182 641 742 506 881 426 NA NA NA NA NA NA NA 31817 FUN_001183 6 27 32 45 42 NA NA NA NA NA NA NA 31818 FUN_001180 2330 871 1127 1635 1351 NA NA NA NA NA NA NA 31819 FUN_001181 2043 1181 993 2039 1591 NA NA NA NA NA NA NA 31820 FUN_001186 56 45 40 26 97 NA NA NA NA NA NA NA 31821 FUN_001187 1 0 15 2 8 NA NA NA NA NA NA NA 31822 FUN_001184 4229 3512 2111 4237 3565 ntLink_6:9492328-9509019 Q5ZIA5 1.05e-27 Coatomer subunit beta (Beta-coat protein) (Beta-COP) Gallus gallus (Chicken) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; intra-Golgi vesicle-mediated transport [GO:0006891]; intracellular protein transport [GO:0006886] GO:0000139; GO:0005198; GO:0005829; GO:0006886; GO:0006888; GO:0006891; GO:0030126 31823 FUN_001185 2673 1049 853 1639 1110 ntLink_6:9515184-9537797 P04323 3.97e-45 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 31824 FUN_001185 2673 1049 853 1639 1110 ntLink_6:9515184-9537797 P04323 3.97e-45 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 31825 FUN_001188 2218 1012 1227 1378 1230 NA NA NA NA NA NA NA 31826 FUN_001189 1360 662 560 1111 855 ntLink_6:9591302-9603388 P70428 9.96e-23 Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog) Mus musculus (Mouse) cellular polysaccharide biosynthetic process [GO:0033692]; cellular response to fibroblast growth factor stimulus [GO:0044344]; chondrocyte differentiation [GO:0002062]; endochondral bone morphogenesis [GO:0060350]; fluid transport [GO:0042044]; gene expression [GO:0010467]; glycosaminoglycan biosynthetic process [GO:0006024]; heart contraction [GO:0060047]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin biosynthetic process [GO:0030210]; mesoderm formation [GO:0001707]; multicellular organismal water homeostasis [GO:0050891]; ossification [GO:0001503]; protein N-linked glycosylation [GO:0006487]; regulation of blood pressure [GO:0008217]; sodium ion homeostasis [GO:0055078]; sulfation [GO:0051923]; vasodilation [GO:0042311] GO:0000139; GO:0001503; GO:0001707; GO:0002062; GO:0005783; GO:0005789; GO:0005794; GO:0006024; GO:0006487; GO:0008217; GO:0008375; GO:0010467; GO:0015012; GO:0015014; GO:0015020; GO:0016757; GO:0030210; GO:0033692; GO:0042044; GO:0042311; GO:0042328; GO:0042803; GO:0043541; GO:0044344; GO:0046872; GO:0046982; GO:0050508; GO:0050509; GO:0050891; GO:0051923; GO:0055078; GO:0060047; GO:0060350 31827 FUN_033436 0 0 4 0 23 NA NA NA NA NA NA NA 31828 FUN_025809 2038 1272 1138 4455 3719 NA NA NA NA NA NA NA 31829 FUN_025808 1622 1746 935 868 903 NA NA NA NA NA NA NA 31830 FUN_035184 936 2037 720 612 513 NA NA NA NA NA NA NA 31831 FUN_025801 125 32 134 118 70 ptg000020l:777458-777740 Q3ZC26 7.23e-25 Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) Bos taurus (Bovine) apoptotic process [GO:0006915]; myo-inositol transport [GO:0015798] GO:0005365; GO:0005412; GO:0005886; GO:0006915; GO:0015798; GO:0016020; GO:0016324 31832 FUN_025800 809 412 406 616 514 NA NA NA NA NA NA NA 31833 FUN_025803 508 262 454 237 423 NA NA NA NA NA NA NA 31834 FUN_025802 8645 5439 3494 6750 5874 ptg000020l:784433-791031 Q16P20 2.98e-49 Probable citrate synthase 2, mitochondrial (EC 2.3.3.16) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099] GO:0004108; GO:0005759; GO:0005975; GO:0006099; GO:0006101 31835 FUN_025802 8645 5439 3494 6750 5874 ptg000020l:784433-791031 Q16P20 1.82e-28 Probable citrate synthase 2, mitochondrial (EC 2.3.3.16) Aedes aegypti (Yellowfever mosquito) (Culex aegypti) carbohydrate metabolic process [GO:0005975]; citrate metabolic process [GO:0006101]; tricarboxylic acid cycle [GO:0006099] GO:0004108; GO:0005759; GO:0005975; GO:0006099; GO:0006101 31836 FUN_025805 399 196 214 221 124 ptg000020l:799487-800756 Q17094 1.9e-25 Rhodopsin Alloteuthis subulata (Squid) (Loligo subulata) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881; GO:0016020; GO:0016918 31837 FUN_025804 289 257 395 361 642 NA NA NA NA NA NA NA 31838 FUN_025807 962 285 786 624 239 NA NA NA NA NA NA NA 31839 FUN_025806 6101 3859 3316 6671 3414 NA NA NA NA NA NA NA 31840 FUN_035186 0 0 4 5 8 NA NA NA NA NA NA NA 31841 FUN_001965 191 98 18 103 114 NA NA NA NA NA NA NA 31842 FUN_030353 5 0 7 2 26 ptg000023l:10681458-10682221 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 31843 FUN_035180 1213 1179 533 1503 1142 NA NA NA NA NA NA NA 31844 FUN_035879 0 0 6 0 0 NA NA NA NA NA NA NA 31845 FUN_035878 6348 4505 2462 5030 2636 ptg000025l:12834784-12844681 Q8MH63 2.02e-31 Putative L-type amino acid transporter 1-like protein MLAS (hLAT1 3-transmembrane protein MLAS) (hLAT1 3TM MLAS) Homo sapiens (Human) NA GO:0015179; GO:0016020 31846 FUN_035875 20 15 50 31 69 NA NA NA NA NA NA NA 31847 FUN_026530 231 161 165 203 97 NA NA NA NA NA NA NA 31848 FUN_035877 415 233 464 517 962 NA NA NA NA NA NA NA 31849 FUN_035182 16977 16050 9639 11052 5216 NA NA NA NA NA NA NA 31850 FUN_035871 1288 871 795 1053 865 NA NA NA NA NA NA NA 31851 FUN_035870 265 117 72 191 81 NA NA NA NA NA NA NA 31852 FUN_035873 11 59 42 137 114 NA NA NA NA NA NA NA 31853 FUN_035872 98 72 134 196 167 NA NA NA NA NA NA NA 31854 FUN_004299 234 6 52 53 94 ntLink_8:21668083-21670889 P11023 2.67e-34 Ras-related protein Rab-3A (SMG P25A) Bos taurus (Bovine) axonogenesis [GO:0007409]; calcium-ion regulated exocytosis [GO:0017156]; lung development [GO:0030324]; maintenance of presynaptic active zone structure [GO:0048790]; mitochondrion organization [GO:0007005]; neuromuscular synaptic transmission [GO:0007274]; post-embryonic development [GO:0009791]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; regulation of exocytosis [GO:0017157]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; respiratory system process [GO:0003016]; response to electrical stimulus [GO:0051602]; sensory perception of touch [GO:0050975]; synaptic vesicle exocytosis [GO:0016079]; synaptic vesicle maturation [GO:0016188]; vesicle docking involved in exocytosis [GO:0006904] GO:0003016; GO:0003924; GO:0005525; GO:0005764; GO:0005768; GO:0005829; GO:0005886; GO:0006904; GO:0007005; GO:0007274; GO:0007409; GO:0008021; GO:0009306; GO:0009791; GO:0016020; GO:0016079; GO:0016188; GO:0017156; GO:0017157; GO:0030324; GO:0030424; GO:0030672; GO:0031489; GO:0031630; GO:0043231; GO:0048786; GO:0048790; GO:0050975; GO:0051602; GO:0072659; GO:0098793; GO:0098794 31855 FUN_004298 9894 8789 4820 9272 5682 ntLink_8:21662274-21665194 P25228 1.82e-50 Ras-related protein Rab-3 Drosophila melanogaster (Fruit fly) cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]; viral entry into host cell [GO:0046718] GO:0003924; GO:0005525; GO:0005768; GO:0005886; GO:0006904; GO:0007269; GO:0008021; GO:0009306; GO:0016192; GO:0017157; GO:0031489; GO:0031630; GO:0031982; GO:0032482; GO:0043231; GO:0045202; GO:0046718; GO:0046928; GO:0048172; GO:0048786; GO:0048789; GO:0048790; GO:0072659 31856 FUN_004298 9894 8789 4820 9272 5682 ntLink_8:21662274-21665194 P25228 1.82e-50 Ras-related protein Rab-3 Drosophila melanogaster (Fruit fly) cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]; viral entry into host cell [GO:0046718] GO:0003924; GO:0005525; GO:0005768; GO:0005886; GO:0006904; GO:0007269; GO:0008021; GO:0009306; GO:0016192; GO:0017157; GO:0031489; GO:0031630; GO:0031982; GO:0032482; GO:0043231; GO:0045202; GO:0046718; GO:0046928; GO:0048172; GO:0048786; GO:0048789; GO:0048790; GO:0072659 31857 FUN_004298 9894 8789 4820 9272 5682 ntLink_8:21662274-21665194 P25228 1.33e-43 Ras-related protein Rab-3 Drosophila melanogaster (Fruit fly) cytoskeletal matrix organization at active zone [GO:0048789]; maintenance of presynaptic active zone structure [GO:0048790]; neurotransmitter secretion [GO:0007269]; protein localization to plasma membrane [GO:0072659]; protein secretion [GO:0009306]; Rab protein signal transduction [GO:0032482]; regulation of exocytosis [GO:0017157]; regulation of neurotransmitter secretion [GO:0046928]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic vesicle fusion to presynaptic active zone membrane [GO:0031630]; vesicle docking involved in exocytosis [GO:0006904]; vesicle-mediated transport [GO:0016192]; viral entry into host cell [GO:0046718] GO:0003924; GO:0005525; GO:0005768; GO:0005886; GO:0006904; GO:0007269; GO:0008021; GO:0009306; GO:0016192; GO:0017157; GO:0031489; GO:0031630; GO:0031982; GO:0032482; GO:0043231; GO:0045202; GO:0046718; GO:0046928; GO:0048172; GO:0048786; GO:0048789; GO:0048790; GO:0072659 31858 FUN_026532 447 91 131 562 250 NA NA NA NA NA NA NA 31859 FUN_001966 211 188 68 304 102 NA NA NA NA NA NA NA 31860 FUN_004291 12652 15974 9200 6793 4604 NA NA NA NA NA NA NA 31861 FUN_004290 1603 1598 1299 1289 955 ntLink_8:21577346-21580317 P35384 1.8e-87 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (BoPCaR1) (PCaR1) Bos taurus (Bovine) calcium ion import [GO:0070509]; calcium ion transport [GO:0006816]; cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of gene expression [GO:0010628]; regulation of calcium ion transport [GO:0051924]; vasodilation [GO:0042311] GO:0001503; GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006816; GO:0006874; GO:0007186; GO:0007254; GO:0008284; GO:0010628; GO:0016597; GO:0032781; GO:0042311; GO:0042803; GO:0043679; GO:0051924; GO:0070509 31862 FUN_004293 1971 1260 1205 2269 1924 NA NA NA NA NA NA NA 31863 FUN_004292 1333 1375 711 1915 1223 ntLink_8:21587249-21588476 Q08CD5 1.49e-120 Ribitol-5-phosphate xylosyltransferase 1 (EC 2.4.2.61) (Transmembrane protein 5) (UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) protein O-linked mannosylation [GO:0035269] GO:0000139; GO:0005794; GO:0035269; GO:0120053 31864 FUN_004295 1367 2973 1135 1618 757 NA NA NA NA NA NA NA 31865 FUN_004294 47 11 22 95 29 NA NA NA NA NA NA NA 31866 FUN_004297 0 8 0 0 0 NA NA NA NA NA NA NA 31867 FUN_004296 0 17 13 43 30 NA NA NA NA NA NA NA 31868 FUN_040949 2845 2054 847 1556 1746 ptg000033l:298585-339417 Q8I7P9 1.13e-39 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 31869 FUN_040948 0 0 0 17 0 NA NA NA NA NA NA NA 31870 FUN_040947 33 67 24 58 0 NA NA NA NA NA NA NA 31871 FUN_040946 297 204 126 347 156 ptg000033l:253216-265281 Q9J569 6.09e-23 Putative ankyrin repeat protein FPV162 Fowlpox virus (strain NVSL) (FPV) NA NA 31872 FUN_040941 27 7 17 2 1 NA NA NA NA NA NA NA 31873 FUN_040943 22 28 5 3 13 NA NA NA NA NA NA NA 31874 FUN_040942 20 16 9 11 7 NA NA NA NA NA NA NA 31875 FUN_012577 0 0 15 0 0 NA NA NA NA NA NA NA 31876 FUN_012576 0 0 0 18 8 NA NA NA NA NA NA NA 31877 FUN_012575 5 10 32 170 103 ptg000008l:10062027-10067757 Q2EG98 4.32e-32 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 31878 FUN_012575 5 10 32 170 103 ptg000008l:10062027-10067757 Q2EG98 5.46e-25 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 31879 FUN_012574 13 0 0 0 0 NA NA NA NA NA NA NA 31880 FUN_012573 59 25 14 36 36 ptg000008l:10037761-10043652 Q7TN88 2.37e-31 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 31881 FUN_012572 16 29 10 51 40 ptg000008l:10035632-10037551 Q2EG98 1.03e-34 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 31882 FUN_012571 938 796 373 1068 892 ptg000008l:10025036-10034175 Q96NI8 3.55e-56 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31883 FUN_012571 938 796 373 1068 892 ptg000008l:10025036-10034175 Q96NI8 3.78e-49 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31884 FUN_012571 938 796 373 1068 892 ptg000008l:10025036-10034175 Q96NI8 1.59e-47 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31885 FUN_012571 938 796 373 1068 892 ptg000008l:10025036-10034175 Q96NI8 8.56e-44 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31886 FUN_012571 938 796 373 1068 892 ptg000008l:10025036-10034175 Q96NI8 5.03e-39 Zinc finger protein 570 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 31887 FUN_012570 0 0 2 0 6 NA NA NA NA NA NA NA 31888 FUN_012579 38 36 0 47 40 ptg000008l:10082333-10084305 Q2EG98 1.16e-27 Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of mechanical stimulus [GO:0050982]; sensory perception of sour taste [GO:0050915] GO:0001581; GO:0005262; GO:0005509; GO:0005886; GO:0006812; GO:0016020; GO:0030246; GO:0034703; GO:0043235; GO:0050915; GO:0050982; GO:0071468 31889 FUN_012578 0 22 8 0 0 NA NA NA NA NA NA NA 31890 FUN_016267 0 0 0 0 15 NA NA NA NA NA NA NA 31891 FUN_016266 30 8 14 64 31 NA NA NA NA NA NA NA 31892 FUN_016265 41 46 10 96 92 NA NA NA NA NA NA NA 31893 FUN_016263 3 0 0 0 43 NA NA NA NA NA NA NA 31894 FUN_016262 0 0 33 0 26 NA NA NA NA NA NA NA 31895 FUN_016269 1 0 6 0 3 NA NA NA NA NA NA NA 31896 FUN_028019 148 29 54 157 40 ptg000021l:14956862-14971454 Q8BG19 4.09e-41 Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane and TPR repeat-containing protein 4) Mus musculus (Mouse) endoplasmic reticulum unfolded protein response [GO:0030968]; outer hair cell apoptotic process [GO:1905584]; positive regulation of endoplasmic reticulum calcium ion concentration [GO:0032470]; protein O-linked mannosylation [GO:0035269]; sensory perception of sound [GO:0007605] GO:0000030; GO:0004169; GO:0005783; GO:0007605; GO:0016020; GO:0030968; GO:0032470; GO:0035269; GO:0051117; GO:1905584 31897 FUN_028018 210 154 51 59 161 NA NA NA NA NA NA NA 31898 FUN_028015 1396 1497 975 1474 1604 NA NA NA NA NA NA NA 31899 FUN_028014 6692 4404 3455 6086 3514 ptg000021l:14619248-14685361 Q99315 4.47e-84 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 31900 FUN_028016 34 28 0 76 23 NA NA NA NA NA NA NA 31901 FUN_028011 741 1069 77 245 113 ptg000021l:14561699-14593065 P21328 4.01e-33 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 31902 FUN_028010 17 1 4 2 25 NA NA NA NA NA NA NA 31903 FUN_028012 66 58 14 138 0 NA NA NA NA NA NA NA 31904 FUN_043412 1414 1020 948 1187 1969 NA NA NA NA NA NA NA 31905 FUN_043413 2102 943 730 2723 1327 NA NA NA NA NA NA NA 31906 FUN_043410 323 367 289 249 267 ptg000047l:8148819-8149947 P53454 5.72e-33 D(5)-like dopamine receptor Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 31907 FUN_043411 82 60 0 25 29 ptg000047l:8157003-8161627 P07700 3.31e-30 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (Beta-T) Meleagris gallopavo (Wild turkey) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823]; regulation of circadian sleep/wake cycle, sleep [GO:0045187] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0016020; GO:0042802; GO:0043547; GO:0045187; GO:0045823; GO:0071880 31908 FUN_043416 89 58 42 102 252 NA NA NA NA NA NA NA 31909 FUN_043417 8359 5833 1923 8007 4013 NA NA NA NA NA NA NA 31910 FUN_043414 3600 2704 1678 2384 1504 NA NA NA NA NA NA NA 31911 FUN_043415 106 0 90 88 627 NA NA NA NA NA NA NA 31912 FUN_043418 11810 14642 8030 11843 1810 NA NA NA NA NA NA NA 31913 FUN_043419 4084 2668 1930 1925 2002 ptg000047l:8282246-8304437 Q96DM1 8.99e-54 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 31914 FUN_041308 3 7 3 0 1 NA NA NA NA NA NA NA 31915 FUN_002295 1 0 0 0 8 NA NA NA NA NA NA NA 31916 FUN_002292 0 0 0 0 7 NA NA NA NA NA NA NA 31917 FUN_016109 2340 1652 785 1458 1087 NA NA NA NA NA NA NA 31918 FUN_016102 2237 1604 1201 2109 1278 NA NA NA NA NA NA NA 31919 FUN_016103 4703 4328 1513 5804 3555 ptg000010l:1594998-1596400 O95721 6.74e-26 Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagosome membrane docking [GO:0016240]; cilium assembly [GO:0060271]; exocytosis [GO:0006887]; membrane fusion [GO:0061025]; protein transport [GO:0015031]; synaptic vesicle fusion to presynaptic active zone membrane [GO:0031629]; synaptic vesicle priming [GO:0016082]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] GO:0000139; GO:0000421; GO:0005484; GO:0005654; GO:0005737; GO:0005776; GO:0005813; GO:0005829; GO:0005886; GO:0006887; GO:0006903; GO:0006906; GO:0015031; GO:0016082; GO:0016240; GO:0019905; GO:0020018; GO:0031201; GO:0031629; GO:0035577; GO:0060271; GO:0061025; GO:0097352; GO:0098793 31920 FUN_042129 174 15 78 54 83 ptg000036l:952774-960691 Q8I7P9 2.68e-59 Retrovirus-related Pol polyprotein from transposon opus [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508]; transposition, DNA-mediated [GO:0006313] GO:0003676; GO:0003887; GO:0003964; GO:0004519; GO:0005634; GO:0006313; GO:0006508; GO:0008233; GO:0015074; GO:0042575 31921 FUN_016100 2026 1417 866 1870 1891 NA NA NA NA NA NA NA 31922 FUN_006366 259 189 64 190 83 NA NA NA NA NA NA NA 31923 FUN_022710 6929 7767 3461 6017 5534 NA NA NA NA NA NA NA 31924 FUN_009176 0 7 0 52 17 NA NA NA NA NA NA NA 31925 FUN_022712 1127 551 442 1347 1843 NA NA NA NA NA NA NA 31926 FUN_022715 2720 1342 740 1701 2991 NA NA NA NA NA NA NA 31927 FUN_009171 2 0 0 6 0 ptg000004l:3514947-3515780 Q96AY4 1.97e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31928 FUN_022717 158 117 90 119 202 NA NA NA NA NA NA NA 31929 FUN_022718 2943 1182 1696 3745 2077 ptg000016l:12611861-12622756 Q6ZWK6 1.81e-25 Transmembrane protease serine 11F (EC 3.4.21.-) (Airway trypsin-like protease 4) Homo sapiens (Human) proteolysis [GO:0006508]; regulation of water loss via skin [GO:0033561] GO:0004252; GO:0005576; GO:0005886; GO:0006508; GO:0009986; GO:0033561 31930 FUN_022719 586 681 469 915 512 NA NA NA NA NA NA NA 31931 FUN_009179 0 114 0 0 6 NA NA NA NA NA NA NA 31932 FUN_009178 12 14 0 77 0 ptg000004l:3601615-3605818 Q96AY4 1.5e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31933 FUN_009178 12 14 0 77 0 ptg000004l:3601615-3605818 Q96AY4 1.4e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31934 FUN_009178 12 14 0 77 0 ptg000004l:3601615-3605818 Q96AY4 1.16e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31935 FUN_009178 12 14 0 77 0 ptg000004l:3601615-3605818 Q96AY4 2.33e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31936 FUN_009178 12 14 0 77 0 ptg000004l:3601615-3605818 Q96AY4 1.91e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31937 FUN_009178 12 14 0 77 0 ptg000004l:3601615-3605818 Q96AY4 3.67e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 31938 FUN_016104 2911 1469 1331 2616 2296 NA NA NA NA NA NA NA 31939 FUN_042225 14 0 15 5 92 NA NA NA NA NA NA NA 31940 FUN_006369 944 543 242 945 835 NA NA NA NA NA NA NA 31941 FUN_029874 1404 511 628 517 1119 NA NA NA NA NA NA NA 31942 FUN_029875 196 55 89 90 149 NA NA NA NA NA NA NA 31943 FUN_029876 707 235 392 379 439 NA NA NA NA NA NA NA 31944 FUN_006368 478 710 259 431 395 ptg000001l:11546175-11621845 P21328 9.02e-23 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 31945 FUN_029873 0 0 0 0 25 NA NA NA NA NA NA NA 31946 FUN_029878 96 46 32 244 25 NA NA NA NA NA NA NA 31947 FUN_029879 5 55 8 40 20 NA NA NA NA NA NA NA 31948 FUN_040168 5688 3793 3060 2987 2797 NA NA NA NA NA NA NA 31949 FUN_040167 242 196 187 378 519 NA NA NA NA NA NA NA 31950 FUN_040166 60 88 69 100 25 NA NA NA NA NA NA NA 31951 FUN_040165 0 0 49 0 0 NA NA NA NA NA NA NA 31952 FUN_040164 0 23 2 0 9 NA NA NA NA NA NA NA 31953 FUN_041505 627 865 318 783 485 ptg000035l:4470756-4474963 A7RR34 4.77e-26 Protein Flattop homolog (Cilia- and flagella-associated protein 126) Nematostella vectensis (Starlet sea anemone) cilium organization [GO:0044782] GO:0005737; GO:0005929; GO:0016324; GO:0036064; GO:0044782 31954 FUN_040162 4 0 0 51 8 ptg000031l:4963053-4976807 Q90Y54 4.85e-30 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 31955 FUN_040162 4 0 0 51 8 ptg000031l:4963053-4976807 Q90Y54 4.85e-30 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 31956 FUN_040162 4 0 0 51 8 ptg000031l:4963053-4976807 Q90Y54 4.85e-30 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 31957 FUN_040162 4 0 0 51 8 ptg000031l:4963053-4976807 Q90Y54 4.85e-30 Protein jagged-1b (Jagged1b) (Jagged3) Danio rerio (Zebrafish) (Brachydanio rerio) auditory receptor cell development [GO:0060117]; cartilage development involved in endochondral bone morphogenesis [GO:0060351]; cranial skeletal system development [GO:1904888]; dorsal/ventral pattern formation [GO:0009953]; exocrine pancreas development [GO:0031017]; face morphogenesis [GO:0060325]; fin regeneration [GO:0031101]; inner ear morphogenesis [GO:0042472]; intrahepatic bile duct development [GO:0035622]; liver development [GO:0001889]; Notch signaling pathway [GO:0007219]; otolith morphogenesis [GO:0032474]; pancreas development [GO:0031016]; semicircular canal development [GO:0060872]; semicircular canal morphogenesis [GO:0048752]; thyroid gland development [GO:0030878] GO:0001889; GO:0005112; GO:0005509; GO:0005886; GO:0007219; GO:0009953; GO:0030878; GO:0031016; GO:0031017; GO:0031101; GO:0032474; GO:0035622; GO:0042472; GO:0048752; GO:0060117; GO:0060325; GO:0060351; GO:0060872; GO:1904888 31958 FUN_040161 44 0 78 120 160 ptg000031l:4932031-4944454 P21783 4.6e-21 Neurogenic locus notch homolog protein 1 (Notch 1) (xOTCH) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus laevis (African clawed frog) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793] GO:0000122; GO:0001525; GO:0005509; GO:0005654; GO:0005886; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 31959 FUN_040161 44 0 78 120 160 ptg000031l:4932031-4944454 P21783 4.6e-21 Neurogenic locus notch homolog protein 1 (Notch 1) (xOTCH) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus laevis (African clawed frog) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793] GO:0000122; GO:0001525; GO:0005509; GO:0005654; GO:0005886; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 31960 FUN_040161 44 0 78 120 160 ptg000031l:4932031-4944454 P21783 4.6e-21 Neurogenic locus notch homolog protein 1 (Notch 1) (xOTCH) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus laevis (African clawed frog) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793] GO:0000122; GO:0001525; GO:0005509; GO:0005654; GO:0005886; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 31961 FUN_040161 44 0 78 120 160 ptg000031l:4932031-4944454 P21783 4.6e-21 Neurogenic locus notch homolog protein 1 (Notch 1) (xOTCH) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)] Xenopus laevis (African clawed frog) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; cilium assembly [GO:0060271]; negative regulation of transcription by RNA polymerase II [GO:0000122]; Notch signaling involved in heart development [GO:0061314]; regulation of developmental process [GO:0050793] GO:0000122; GO:0001525; GO:0005509; GO:0005654; GO:0005886; GO:0030154; GO:0038023; GO:0050793; GO:0060271; GO:0061314 31962 FUN_010712 1879 702 277 1185 724 NA NA NA NA NA NA NA 31963 FUN_010714 636 314 159 250 334 NA NA NA NA NA NA NA 31964 FUN_015941 7 0 0 0 0 NA NA NA NA NA NA NA 31965 FUN_015940 293 0 0 0 0 NA NA NA NA NA NA NA 31966 FUN_032423 8516 2603 2018 3503 1859 NA NA NA NA NA NA NA 31967 FUN_032422 334 281 286 254 551 NA NA NA NA NA NA NA 31968 FUN_032421 5953 6809 2589 3563 1582 NA NA NA NA NA NA NA 31969 FUN_032420 17092 15321 14628 37374 19517 NA NA NA NA NA NA NA 31970 FUN_032427 1171 728 700 744 1230 ptg000023l:31829057-31845733 Q2KJJ5 5.45e-21 Transducin beta-like protein 3 Bos taurus (Bovine) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000480]; endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000472] GO:0000472; GO:0000480; GO:0005730; GO:0030686; GO:0032040; GO:0034511 31971 FUN_032426 1174 921 610 550 957 NA NA NA NA NA NA NA 31972 FUN_032425 546 296 308 370 690 NA NA NA NA NA NA NA 31973 FUN_032424 949 1167 877 1052 530 NA NA NA NA NA NA NA 31974 FUN_032429 718 810 348 1317 838 NA NA NA NA NA NA NA 31975 FUN_032428 55971 78563 66888 70484 64351 ptg000023l:31846768-31850782 P14148 1.04e-49 60S ribosomal protein L7 Mus musculus (Mouse) cytoplasmic translation [GO:0002181]; maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000463]; ribosomal large subunit biogenesis [GO:0042273]; rRNA processing [GO:0006364]; translation [GO:0006412]; translation at postsynapse [GO:0140242]; translation at presynapse [GO:0140236] GO:0000463; GO:0002181; GO:0003677; GO:0003723; GO:0003729; GO:0003735; GO:0005737; GO:0005829; GO:0005840; GO:0005844; GO:0006364; GO:0006412; GO:0008097; GO:0014069; GO:0022625; GO:0022626; GO:0031672; GO:0042273; GO:0042802; GO:0045202; GO:0098793; GO:0098794; GO:0140236; GO:0140242; GO:1990904 31976 FUN_028839 193 98 88 159 262 NA NA NA NA NA NA NA 31977 FUN_028838 1902 1505 1045 1290 835 NA NA NA NA NA NA NA 31978 FUN_028837 1764 1139 648 1233 887 NA NA NA NA NA NA NA 31979 FUN_028832 0 6 382 85 0 NA NA NA NA NA NA NA 31980 FUN_028831 273 310 470 1314 530 ptg000022l:4735680-4744720 Q9NVH0 3.16e-31 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 31981 FUN_028831 273 310 470 1314 530 ptg000022l:4735680-4744720 Q9NVH0 9.18e-22 Exonuclease 3'-5' domain-containing protein 2 (EC 3.1.11.1) (3'-5' exoribonuclease EXD2) (EC 3.1.13.-) (Exonuclease 3'-5' domain-like-containing protein 2) Homo sapiens (Human) DNA double-strand break processing [GO:0000729]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; replication fork processing [GO:0031297] GO:0000175; GO:0000287; GO:0000724; GO:0000729; GO:0003676; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005759; GO:0006302; GO:0008296; GO:0008310; GO:0008408; GO:0008852; GO:0030145; GO:0031297; GO:0042803; GO:0045111; GO:0090305; GO:0090734 31982 FUN_028830 0 0 0 9 27 NA NA NA NA NA NA NA 31983 FUN_034397 65 42 120 64 77 NA NA NA NA NA NA NA 31984 FUN_034396 434 744 571 656 310 NA NA NA NA NA NA NA 31985 FUN_018366 44 0 6 0 0 NA NA NA NA NA NA NA 31986 FUN_018367 30 0 38 0 3 NA NA NA NA NA NA NA 31987 FUN_034393 12 23 37 27 19 NA NA NA NA NA NA NA 31988 FUN_041487 5 0 11 0 39 ptg000035l:4247243-4248035 Q9BQ50 7.01e-39 Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2) Homo sapiens (Human) DNA catabolic process, exonucleolytic [GO:0000738]; DNA metabolic process [GO:0006259]; DNA repair [GO:0006281] GO:0000287; GO:0000738; GO:0003677; GO:0005634; GO:0005737; GO:0006259; GO:0006281; GO:0008296; GO:0008853; GO:0042803; GO:0060090 31989 FUN_034391 227 76 47 140 158 NA NA NA NA NA NA NA 31990 FUN_041484 59 43 23 23 28 NA NA NA NA NA NA NA 31991 FUN_041489 26 40 56 21 70 NA NA NA NA NA NA NA 31992 FUN_034390 73 18 11 26 29 NA NA NA NA NA NA NA 31993 FUN_009163 11 0 0 0 138 NA NA NA NA NA NA NA 31994 FUN_019542 3 0 0 9 17 NA NA NA NA NA NA NA 31995 FUN_040324 35 0 15 8 24 ptg000031l:7024446-7025460 P41968 8.08e-25 Melanocortin receptor 3 (MC3-R) Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; circadian regulation of gene expression [GO:0032922]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; homoiothermy [GO:0042309]; locomotor rhythm [GO:0045475]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of blood pressure [GO:0008217]; regulation of feeding behavior [GO:0060259]; regulation of heart rate [GO:0002027]; regulation of metabolic process [GO:0019222]; sodium ion homeostasis [GO:0055078] GO:0002027; GO:0004930; GO:0004977; GO:0004980; GO:0005737; GO:0005886; GO:0007187; GO:0007189; GO:0007200; GO:0008217; GO:0017046; GO:0019222; GO:0032922; GO:0042309; GO:0042923; GO:0045475; GO:0055078; GO:0060259 31996 FUN_029128 551 151 359 499 545 NA NA NA NA NA NA NA 31997 FUN_029129 370 277 208 175 196 NA NA NA NA NA NA NA 31998 FUN_032563 1329 54 7 72 33 NA NA NA NA NA NA NA 31999 FUN_029122 4770 2345 1915 2542 2538 NA NA NA NA NA NA NA 32000 FUN_029123 4736 4997 3160 4647 3848 ptg000022l:8456290-8459361 Q9YH37 3.82e-22 Ras-related protein Rap-1b (EC 3.6.5.2) Cyprinus carpio (Common carp) Rap protein signal transduction [GO:0032486] GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0032486; GO:0070161 32001 FUN_029123 4736 4997 3160 4647 3848 ptg000022l:8456290-8459361 Q9YH37 6e-21 Ras-related protein Rap-1b (EC 3.6.5.2) Cyprinus carpio (Common carp) Rap protein signal transduction [GO:0032486] GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0032486; GO:0070161 32002 FUN_029123 4736 4997 3160 4647 3848 ptg000022l:8456290-8459361 Q9YH37 6e-21 Ras-related protein Rap-1b (EC 3.6.5.2) Cyprinus carpio (Common carp) Rap protein signal transduction [GO:0032486] GO:0003925; GO:0005525; GO:0005829; GO:0005886; GO:0032486; GO:0070161 32003 FUN_029120 15 34 21 16 43 NA NA NA NA NA NA NA 32004 FUN_029121 5 0 1 2 6 NA NA NA NA NA NA NA 32005 FUN_029126 227 242 359 230 573 ptg000022l:8488116-8491007 O15541 1.5e-67 E3 ubiquitin-protein ligase RNF113A (EC 2.3.2.27) (Cwc24 homolog) (RING finger protein 113A) (Zinc finger protein 183) Homo sapiens (Human) DNA repair [GO:0006281]; isopeptide cross-linking via N6-glycyl-L-lysine [GO:0018276]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; protein ubiquitination [GO:0016567]; snoRNA splicing [GO:0034247] GO:0000398; GO:0005634; GO:0005654; GO:0005684; GO:0006281; GO:0016567; GO:0016607; GO:0018276; GO:0034247; GO:0046872; GO:0061630; GO:0070100; GO:0071005 32006 FUN_029127 955 619 315 1245 455 NA NA NA NA NA NA NA 32007 FUN_029124 70 104 52 234 58 ptg000022l:8466475-8467510 B3DM66 2.63e-22 G-protein coupled receptor 161 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621] GO:0004930; GO:0005929; GO:0007189; GO:0055037; GO:0060170; GO:1901621 32008 FUN_029125 1022 689 885 1154 706 ptg000022l:8470429-8485588 Q9Y4B4 1.03e-37 Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2) Homo sapiens (Human) NA GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0140658 32009 FUN_029125 1022 689 885 1154 706 ptg000022l:8470429-8485588 Q9Y4B4 9.11e-24 Helicase ARIP4 (EC 3.6.4.12) (Androgen receptor-interacting protein 4) (RAD54-like protein 2) Homo sapiens (Human) NA GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0016887; GO:0140658 32010 FUN_032561 1287 24 8 42 12 ptg000023l:33203688-33204801 Q8AWC7 1.46e-24 Alpha-(1,3)-fucosyltransferase 11 (EC 2.4.1.-) (Fucosyltransferase XI) (Fuc-TXI) (FucT-XI) (Galactoside 3-L-fucosyltransferase 11) (Fucosyltransferase 11) Gallus gallus (Chicken) fucosylation [GO:0036065]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0032580; GO:0036065; GO:0046920 32011 FUN_032566 11 0 0 0 0 NA NA NA NA NA NA NA 32012 FUN_035726 4 50 12 17 6 NA NA NA NA NA NA NA 32013 FUN_032567 218 0 30 4 39 NA NA NA NA NA NA NA 32014 FUN_039378 937 23 436 1230 650 ptg000029c:842741-870072 Q7RTR2 5.92e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32015 FUN_039378 937 23 436 1230 650 ptg000029c:842741-870072 Q7RTR2 8.66e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32016 FUN_039378 937 23 436 1230 650 ptg000029c:842741-870072 Q7RTR2 9.69e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32017 FUN_039378 937 23 436 1230 650 ptg000029c:842741-870072 Q7RTR2 9.02e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32018 FUN_039378 937 23 436 1230 650 ptg000029c:842741-870072 Q7RTR2 3.49e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32019 FUN_039379 2 26 0 6 0 NA NA NA NA NA NA NA 32020 FUN_039376 77 62 16 119 16 ptg000029c:812679-815664 Q63E45 8.21e-44 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain ZK / E33L) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 32021 FUN_039374 382 83 134 483 167 ptg000029c:780166-784925 Q7RTR2 2.32e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32022 FUN_039374 382 83 134 483 167 ptg000029c:780166-784925 Q7RTR2 3.35e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32023 FUN_039374 382 83 134 483 167 ptg000029c:780166-784925 Q7RTR2 5.42e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32024 FUN_039374 382 83 134 483 167 ptg000029c:780166-784925 Q7RTR2 3.02e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32025 FUN_039374 382 83 134 483 167 ptg000029c:780166-784925 Q7RTR2 6.89e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32026 FUN_039374 382 83 134 483 167 ptg000029c:780166-784925 Q7RTR2 2.3e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32027 FUN_039372 166 21 75 65 204 NA NA NA NA NA NA NA 32028 FUN_039373 249 64 54 174 27 NA NA NA NA NA NA NA 32029 FUN_039371 145 99 55 2 66 NA NA NA NA NA NA NA 32030 FUN_003859 229 0 105 427 249 ntLink_8:16248780-16250652 A0A0C2SRU0 2.51e-74 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32031 FUN_003856 50 0 95 24 77 ntLink_8:16210439-16212057 A0A0C2SRU0 2.16e-75 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32032 FUN_004801 27 0 0 8 11 NA NA NA NA NA NA NA 32033 FUN_003854 1608 1188 776 1228 2006 NA NA NA NA NA NA NA 32034 FUN_003855 397 0 874 0 144 NA NA NA NA NA NA NA 32035 FUN_004804 10379 4750 5273 4584 5402 NA NA NA NA NA NA NA 32036 FUN_004805 109 98 65 141 105 ntLink_8:27244316-27247367 Q9LYN8 7.65e-21 Leucine-rich repeat receptor protein kinase EMS1 (EC 2.7.11.1) (Protein EXCESS MICROSPOROCYTES 1) (Protein EXTRA SPOROGENOUS CELLS) Arabidopsis thaliana (Mouse-ear cress) anther wall tapetum cell fate specification [GO:0010234]; microsporogenesis [GO:0009556]; protein autophosphorylation [GO:0046777] GO:0004674; GO:0005524; GO:0005886; GO:0009556; GO:0010234; GO:0016020; GO:0019199; GO:0046777; GO:0106310 32037 FUN_025482 0 0 0 0 50 NA NA NA NA NA NA NA 32038 FUN_004806 3 60 36 128 40 NA NA NA NA NA NA NA 32039 FUN_032271 5025 4993 3247 5044 2112 ptg000023l:30396296-30400117 Q05A13 1.84e-40 Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-) Mus musculus (Mouse) NA GO:0005811; GO:0016616 32040 FUN_032271 5025 4993 3247 5044 2112 ptg000023l:30396296-30400117 Q05A13 4.17e-21 Short-chain dehydrogenase/reductase family 16C member 6 (EC 1.1.1.-) Mus musculus (Mouse) NA GO:0005811; GO:0016616 32041 FUN_011501 24 0 10 0 45 NA NA NA NA NA NA NA 32042 FUN_004707 14 0 9 30 6 NA NA NA NA NA NA NA 32043 FUN_010709 53 21 52 27 61 NA NA NA NA NA NA NA 32044 FUN_003574 0 26 0 72 31 NA NA NA NA NA NA NA 32045 FUN_010702 3169 3464 1765 3731 1660 ptg000007l:1944634-1948050 Q2T9Q6 1.88e-37 Tektin-2 Bos taurus (Bovine) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159] GO:0005815; GO:0005879; GO:0015630; GO:0030317; GO:0031514; GO:0036159; GO:0060271; GO:0060294 32046 FUN_010702 3169 3464 1765 3731 1660 ptg000007l:1944634-1948050 Q2T9Q6 1.58e-27 Tektin-2 Bos taurus (Bovine) cilium assembly [GO:0060271]; cilium movement involved in cell motility [GO:0060294]; flagellated sperm motility [GO:0030317]; inner dynein arm assembly [GO:0036159] GO:0005815; GO:0005879; GO:0015630; GO:0030317; GO:0031514; GO:0036159; GO:0060271; GO:0060294 32047 FUN_010701 1208 582 499 977 1001 NA NA NA NA NA NA NA 32048 FUN_010706 2 13 0 73 21 ptg000007l:1971778-1983342 Q09575 2.26e-25 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 32049 FUN_004705 31 14 13 12 20 NA NA NA NA NA NA NA 32050 FUN_010704 0 19 36 25 88 NA NA NA NA NA NA NA 32051 FUN_031707 1007 316 263 784 760 ptg000023l:24576003-24580772 Q9BV44 1.24e-30 tRNA (guanine(6)-N2)-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3) Homo sapiens (Human) tRNA methylation [GO:0030488]; tRNA N2-guanine methylation [GO:0002940] GO:0000049; GO:0002940; GO:0004809; GO:0005730; GO:0005737; GO:0005829; GO:0016423; GO:0030488 32052 FUN_031707 1007 316 263 784 760 ptg000023l:24576003-24580772 Q9BV44 1.31e-28 tRNA (guanine(6)-N2)-methyltransferase THUMP3 (EC 2.1.1.256) (THUMP domain-containing protein 3) Homo sapiens (Human) tRNA methylation [GO:0030488]; tRNA N2-guanine methylation [GO:0002940] GO:0000049; GO:0002940; GO:0004809; GO:0005730; GO:0005737; GO:0005829; GO:0016423; GO:0030488 32053 FUN_031706 884 843 854 1854 742 NA NA NA NA NA NA NA 32054 FUN_003571 0 0 10 6 34 NA NA NA NA NA NA NA 32055 FUN_031705 129 55 144 106 34 ptg000023l:24567447-24570609 Q5ZKQ6 2.97e-168 DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) Gallus gallus (Chicken) DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0006261; GO:0008622; GO:0042276 32056 FUN_031705 129 55 144 106 34 ptg000023l:24567447-24570609 Q5ZKQ6 6.36e-21 DNA polymerase epsilon subunit 2 (DNA polymerase II subunit 2) (DNA polymerase epsilon subunit B) Gallus gallus (Chicken) DNA-templated DNA replication [GO:0006261]; error-prone translesion synthesis [GO:0042276] GO:0003677; GO:0006261; GO:0008622; GO:0042276 32057 FUN_004702 676 317 199 304 489 NA NA NA NA NA NA NA 32058 FUN_012638 256 328 265 741 273 NA NA NA NA NA NA NA 32059 FUN_012639 3769 2005 2265 4344 3748 ptg000008l:10795472-10865649 Q5THJ4 8.57e-24 Intermembrane lipid transfer protein VPS13D (Vacuolar protein sorting-associated protein 13D) Homo sapiens (Human) lipid transport [GO:0006869]; mitochondrion organization [GO:0007005]; positive regulation of mitophagy [GO:1901526]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623] GO:0006623; GO:0006869; GO:0007005; GO:0019898; GO:0045053; GO:0070062; GO:1901526 32060 FUN_012634 437 355 235 368 371 NA NA NA NA NA NA NA 32061 FUN_012636 637 695 575 640 280 NA NA NA NA NA NA NA 32062 FUN_012637 408 181 237 456 211 NA NA NA NA NA NA NA 32063 FUN_012630 1063 1081 618 978 455 NA NA NA NA NA NA NA 32064 FUN_012632 36 30 0 44 23 NA NA NA NA NA NA NA 32065 FUN_012633 71 25 0 6 0 NA NA NA NA NA NA NA 32066 FUN_018435 17 4 10 84 58 NA NA NA NA NA NA NA 32067 FUN_031700 4203 5893 4430 4964 2781 NA NA NA NA NA NA NA 32068 FUN_013309 10 0 0 0 0 NA NA NA NA NA NA NA 32069 FUN_035187 0 0 16 5 21 NA NA NA NA NA NA NA 32070 FUN_039848 1259 1034 446 761 459 NA NA NA NA NA NA NA 32071 FUN_038968 13 0 10 0 10 NA NA NA NA NA NA NA 32072 FUN_027979 5913 7079 5105 6070 3251 NA NA NA NA NA NA NA 32073 FUN_027978 490 260 280 241 357 ptg000021l:14153591-14157002 P35789 6.39e-41 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 32074 FUN_027978 490 260 280 241 357 ptg000021l:14153591-14157002 P35789 1.34e-33 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 32075 FUN_027978 490 260 280 241 357 ptg000021l:14153591-14157002 P35789 5.2e-33 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 32076 FUN_027978 490 260 280 241 357 ptg000021l:14153591-14157002 P35789 4.26e-31 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 32077 FUN_027978 490 260 280 241 357 ptg000021l:14153591-14157002 P35789 8.57e-30 Zinc finger protein 93 (Zinc finger protein 505) (Zinc finger protein HTF34) Homo sapiens (Human) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transposon integration [GO:0070895]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0006357; GO:0008270; GO:0045892; GO:0070895 32078 FUN_027977 2070 1610 799 1222 1014 NA NA NA NA NA NA NA 32079 FUN_027976 131 93 141 173 169 NA NA NA NA NA NA NA 32080 FUN_027975 507 724 494 552 558 NA NA NA NA NA NA NA 32081 FUN_027974 247 218 94 376 222 ptg000021l:14121217-14127024 P31423 1.03e-105 Metabotropic glutamate receptor 4 (mGluR4) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gamma-aminobutyric acid secretion [GO:0014051]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuron projection development [GO:0031175]; positive regulation of MAPK cascade [GO:0043410]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004930; GO:0005516; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007612; GO:0008066; GO:0008285; GO:0014051; GO:0031175; GO:0031410; GO:0035249; GO:0043005; GO:0043066; GO:0043195; GO:0043198; GO:0043410; GO:0043523; GO:0048306; GO:0048787; GO:0050805; GO:0051932; GO:0051966; GO:0098688; GO:0098978; GO:0099171; GO:0150048; GO:2000300 32082 FUN_027974 247 218 94 376 222 ptg000021l:14121217-14127024 P31423 2.55e-51 Metabotropic glutamate receptor 4 (mGluR4) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gamma-aminobutyric acid secretion [GO:0014051]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuron projection development [GO:0031175]; positive regulation of MAPK cascade [GO:0043410]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004930; GO:0005516; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007612; GO:0008066; GO:0008285; GO:0014051; GO:0031175; GO:0031410; GO:0035249; GO:0043005; GO:0043066; GO:0043195; GO:0043198; GO:0043410; GO:0043523; GO:0048306; GO:0048787; GO:0050805; GO:0051932; GO:0051966; GO:0098688; GO:0098978; GO:0099171; GO:0150048; GO:2000300 32083 FUN_027973 3448 1237 1421 2067 1665 ptg000021l:14106873-14112340 P31423 3.8e-106 Metabotropic glutamate receptor 4 (mGluR4) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gamma-aminobutyric acid secretion [GO:0014051]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuron projection development [GO:0031175]; positive regulation of MAPK cascade [GO:0043410]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004930; GO:0005516; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007612; GO:0008066; GO:0008285; GO:0014051; GO:0031175; GO:0031410; GO:0035249; GO:0043005; GO:0043066; GO:0043195; GO:0043198; GO:0043410; GO:0043523; GO:0048306; GO:0048787; GO:0050805; GO:0051932; GO:0051966; GO:0098688; GO:0098978; GO:0099171; GO:0150048; GO:2000300 32084 FUN_027973 3448 1237 1421 2067 1665 ptg000021l:14106873-14112340 P31423 6.24e-52 Metabotropic glutamate receptor 4 (mGluR4) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway [GO:0007196]; chemical synaptic transmission [GO:0007268]; G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gamma-aminobutyric acid secretion [GO:0014051]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of synaptic transmission [GO:0050805]; neuron projection development [GO:0031175]; positive regulation of MAPK cascade [GO:0043410]; presynaptic modulation of chemical synaptic transmission [GO:0099171]; regulation of neuron apoptotic process [GO:0043523]; regulation of synaptic transmission, glutamatergic [GO:0051966]; regulation of synaptic vesicle exocytosis [GO:2000300]; synaptic transmission, GABAergic [GO:0051932]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0004930; GO:0005516; GO:0005886; GO:0007196; GO:0007216; GO:0007268; GO:0007612; GO:0008066; GO:0008285; GO:0014051; GO:0031175; GO:0031410; GO:0035249; GO:0043005; GO:0043066; GO:0043195; GO:0043198; GO:0043410; GO:0043523; GO:0048306; GO:0048787; GO:0050805; GO:0051932; GO:0051966; GO:0098688; GO:0098978; GO:0099171; GO:0150048; GO:2000300 32085 FUN_027972 12 1 1 4 12 NA NA NA NA NA NA NA 32086 FUN_027971 1680 897 1828 646 1417 NA NA NA NA NA NA NA 32087 FUN_027970 102 56 143 24 228 NA NA NA NA NA NA NA 32088 FUN_014773 48 50 49 36 72 NA NA NA NA NA NA NA 32089 FUN_014772 0 4 24 0 27 NA NA NA NA NA NA NA 32090 FUN_014771 2084 1989 1390 2532 2088 ptg000009l:2929286-2948074 Q4UMH6 4.58e-25 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 32091 FUN_014770 1676 871 1307 1316 1099 NA NA NA NA NA NA NA 32092 FUN_014777 1669 439 466 1088 1117 ptg000009l:2980295-2985941 B3EWZ8 1.02e-46 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 32093 FUN_014777 1669 439 466 1088 1117 ptg000009l:2980295-2985941 B3EWZ8 7.79e-28 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 32094 FUN_014777 1669 439 466 1088 1117 ptg000009l:2980295-2985941 B3EWZ8 4.82e-26 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 32095 FUN_014777 1669 439 466 1088 1117 ptg000009l:2980295-2985941 B3EWZ8 7.63e-22 Ectin Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 32096 FUN_014776 1069 818 731 898 702 NA NA NA NA NA NA NA 32097 FUN_014775 496 156 132 295 166 NA NA NA NA NA NA NA 32098 FUN_014774 104 24 17 18 73 NA NA NA NA NA NA NA 32099 FUN_014779 1677 2392 2546 3029 2885 NA NA NA NA NA NA NA 32100 FUN_014778 90 18 37 13 22 NA NA NA NA NA NA NA 32101 FUN_014360 17 11 0 25 4 NA NA NA NA NA NA NA 32102 FUN_026599 13 0 4 3 43 NA NA NA NA NA NA NA 32103 FUN_026593 25 0 33 0 50 NA NA NA NA NA NA NA 32104 FUN_026590 790 458 508 1157 925 NA NA NA NA NA NA NA 32105 FUN_026591 37 131 87 335 262 NA NA NA NA NA NA NA 32106 FUN_026594 72 0 91 14 79 NA NA NA NA NA NA NA 32107 FUN_026595 2507 1395 1555 3640 1320 NA NA NA NA NA NA NA 32108 FUN_009238 8 0 10 95 16 NA NA NA NA NA NA NA 32109 FUN_009239 28 22 0 23 0 NA NA NA NA NA NA NA 32110 FUN_009234 187 256 121 56 18 ptg000004l:4328589-4333281 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32111 FUN_009234 187 256 121 56 18 ptg000004l:4328589-4333281 Q96AY4 1.85e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32112 FUN_009234 187 256 121 56 18 ptg000004l:4328589-4333281 Q96AY4 9.62e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32113 FUN_009234 187 256 121 56 18 ptg000004l:4328589-4333281 Q96AY4 6.25e-103 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32114 FUN_009235 32 27 0 0 6 NA NA NA NA NA NA NA 32115 FUN_009237 0 66 35 6 18 NA NA NA NA NA NA NA 32116 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 4.09e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32117 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 4.09e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32118 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 3.34e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32119 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 2.67e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32120 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 2.55e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32121 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 7.39e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32122 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 1.07e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32123 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 1.81e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32124 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 1.67e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32125 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 1.22e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32126 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 5.21e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32127 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 7.51e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32128 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 3.81e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32129 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 5.57e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32130 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 2.46e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32131 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 2.71e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32132 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 3.36e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32133 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 3.27e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32134 FUN_009230 29 36 25 59 32 ptg000004l:4278875-4282357 Q96AY4 8.7e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32135 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 1.76e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32136 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 3.28e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32137 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 7.12e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32138 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 2.11e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32139 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 4.54e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32140 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 6.22e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32141 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 2.96e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32142 FUN_009231 254 362 9 729 8 ptg000004l:4288240-4291243 Q96AY4 2.91e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32143 FUN_009232 0 26 0 110 0 NA NA NA NA NA NA NA 32144 FUN_009233 25 0 0 16 0 NA NA NA NA NA NA NA 32145 FUN_019243 190 70 117 930 4 NA NA NA NA NA NA NA 32146 FUN_026628 396 168 398 200 208 ptg000020l:11662240-11665083 Q86VD9 2.38e-68 GPI mannosyltransferase 4 (EC 2.4.1.-) (GPI mannosyltransferase IV) (GPI-MT-IV) (Phosphatidylinositol-glycan biosynthesis class Z protein) (PIG-Z) (SMP3 homolog) (hSMP3) Homo sapiens (Human) GPI anchor biosynthetic process [GO:0006506]; preassembly of GPI anchor in ER membrane [GO:0016254] GO:0000026; GO:0000030; GO:0005783; GO:0005789; GO:0006506; GO:0016254 32147 FUN_019245 332 35 297 938 359 NA NA NA NA NA NA NA 32148 FUN_019247 10 0 7 0 33 NA NA NA NA NA NA NA 32149 FUN_026624 23 8 17 20 180 NA NA NA NA NA NA NA 32150 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 3.32e-103 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32151 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 6.45e-97 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32152 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 1.76e-83 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32153 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 2.71e-81 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32154 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 5.29e-77 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32155 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 3.07e-47 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32156 FUN_026626 20357 10899 10629 14173 8355 ptg000020l:11639457-11649953 P28799 6.58e-25 Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Homo sapiens (Human) astrocyte activation involved in immune response [GO:0002265]; lysosomal lumen acidification [GO:0007042]; lysosomal transport [GO:0007041]; lysosome organization [GO:0007040]; microglial cell activation involved in immune response [GO:0002282]; negative regulation of microglial cell activation [GO:1903979]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of neutrophil activation [GO:1902564]; negative regulation of respiratory burst involved in inflammatory response [GO:0060266]; positive regulation of angiogenesis [GO:0045766]; positive regulation of aspartic-type peptidase activity [GO:1905247]; positive regulation of axon regeneration [GO:0048680]; positive regulation of cell migration [GO:0030335]; positive regulation of defense response to bacterium [GO:1900426]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of inflammatory response to wounding [GO:0106016]; positive regulation of lysosome organization [GO:1905673]; positive regulation of neuron apoptotic process [GO:0043525]; positive regulation of protein folding [GO:1903334]; protein stabilization [GO:0050821]; regulation of inflammatory response [GO:0050727]; signal transduction [GO:0007165] GO:0002265; GO:0002282; GO:0003723; GO:0005125; GO:0005576; GO:0005615; GO:0005764; GO:0005765; GO:0005768; GO:0005770; GO:0005783; GO:0005794; GO:0005802; GO:0005886; GO:0007040; GO:0007041; GO:0007042; GO:0007165; GO:0008083; GO:0010595; GO:0016020; GO:0030335; GO:0035578; GO:0043524; GO:0043525; GO:0045766; GO:0048680; GO:0050679; GO:0050727; GO:0050821; GO:0051087; GO:0060266; GO:0070062; GO:0106016; GO:1900426; GO:1902564; GO:1903334; GO:1903979; GO:1905247; GO:1905673 32157 FUN_026627 33531 12761 8100 17288 12536 ptg000020l:11655039-11657355 Q8BHB0 2.71e-22 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; stress-activated MAPK cascade [GO:0051403]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0007249; GO:0007254; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0051403; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 32158 FUN_026620 101 44 35 59 34 NA NA NA NA NA NA NA 32159 FUN_024666 561 94 466 378 391 ptg000018l:9666333-9672432 Q7RTR2 9.52e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32160 FUN_024666 561 94 466 378 391 ptg000018l:9666333-9672432 Q7RTR2 1.2e-34 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32161 FUN_024666 561 94 466 378 391 ptg000018l:9666333-9672432 Q7RTR2 2.33e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32162 FUN_024666 561 94 466 378 391 ptg000018l:9666333-9672432 Q7RTR2 2.76e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32163 FUN_024666 561 94 466 378 391 ptg000018l:9666333-9672432 Q7RTR2 1.32e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32164 FUN_024667 123 123 62 98 96 NA NA NA NA NA NA NA 32165 FUN_024662 8 58 6 33 7 NA NA NA NA NA NA NA 32166 FUN_024663 158 0 27 4 0 ptg000018l:9627152-9637026 Q7RTR2 2.43e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32167 FUN_024663 158 0 27 4 0 ptg000018l:9627152-9637026 Q7RTR2 4.59e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32168 FUN_024663 158 0 27 4 0 ptg000018l:9627152-9637026 Q7RTR2 9.87e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32169 FUN_024660 393 90 137 45 43 ptg000018l:9557191-9569445 Q7RTR2 3.64e-38 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32170 FUN_024660 393 90 137 45 43 ptg000018l:9557191-9569445 Q7RTR2 2.3e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32171 FUN_024660 393 90 137 45 43 ptg000018l:9557191-9569445 Q7RTR2 8.24e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32172 FUN_024661 1098 460 522 1477 1205 NA NA NA NA NA NA NA 32173 FUN_013300 84 0 0 0 109 NA NA NA NA NA NA NA 32174 FUN_024668 235 590 445 587 663 NA NA NA NA NA NA NA 32175 FUN_024669 141 359 156 223 140 NA NA NA NA NA NA NA 32176 FUN_022336 549 362 154 489 516 NA NA NA NA NA NA NA 32177 FUN_021014 156 94 63 149 187 NA NA NA NA NA NA NA 32178 FUN_021015 146 108 63 244 86 NA NA NA NA NA NA NA 32179 FUN_021012 100 43 79 70 70 NA NA NA NA NA NA NA 32180 FUN_021013 21 0 0 0 0 NA NA NA NA NA NA NA 32181 FUN_021011 0 0 10 0 0 NA NA NA NA NA NA NA 32182 FUN_013307 0 0 0 0 52 NA NA NA NA NA NA NA 32183 FUN_017949 493 111 303 410 265 NA NA NA NA NA NA NA 32184 FUN_017948 256 143 233 276 223 NA NA NA NA NA NA NA 32185 FUN_017941 140 120 161 190 207 ptg000012l:2152028-2153263 Q15814 7.01e-49 Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC) Homo sapiens (Human) post-chaperonin tubulin folding pathway [GO:0007023]; protein folding [GO:0006457]; tubulin complex assembly [GO:0007021] GO:0003924; GO:0005737; GO:0005829; GO:0005856; GO:0005874; GO:0006457; GO:0007021; GO:0007023; GO:0015631; GO:0032391; GO:0051087 32186 FUN_017940 435 470 203 432 340 NA NA NA NA NA NA NA 32187 FUN_017943 1566 699 869 1587 1350 NA NA NA NA NA NA NA 32188 FUN_017942 719 374 242 458 423 NA NA NA NA NA NA NA 32189 FUN_017945 731 336 151 207 94 NA NA NA NA NA NA NA 32190 FUN_017944 930 794 637 897 1033 NA NA NA NA NA NA NA 32191 FUN_017947 2348 1143 1176 1591 1028 NA NA NA NA NA NA NA 32192 FUN_017946 2773 1507 1709 2339 1126 NA NA NA NA NA NA NA 32193 FUN_035815 87 72 56 30 23 NA NA NA NA NA NA NA 32194 FUN_035509 42 26 42 80 65 NA NA NA NA NA NA NA 32195 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 1.8e-32 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32196 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 7.68e-32 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32197 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 2.61e-27 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32198 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 4.01e-27 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32199 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 7.4e-26 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32200 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 3.24e-25 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32201 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 1.38e-24 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32202 FUN_035508 1371 264 317 978 269 ptg000025l:8414626-8431230 Q9R0M0 4.26e-21 Cadherin EGF LAG seven-pass G-type receptor 2 (Flamingo homolog) Mus musculus (Mouse) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060271; GO:0097475; GO:0098609 32203 FUN_038107 1 1 6 1 1 NA NA NA NA NA NA NA 32204 FUN_038104 2177 1327 1073 1579 1462 ptg000027l:2408915-2452493 E9QAM5 2.16e-53 Helicase with zinc finger domain 2 (EC 3.6.4.-) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0030374; GO:0045944; GO:0046872 32205 FUN_038104 2177 1327 1073 1579 1462 ptg000027l:2408915-2452493 E9QAM5 1.3e-22 Helicase with zinc finger domain 2 (EC 3.6.4.-) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) Mus musculus (Mouse) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0030374; GO:0045944; GO:0046872 32206 FUN_038105 1141 514 1385 1157 2390 ptg000027l:2456639-2493632 Q9BYK8 1.29e-47 Helicase with zinc finger domain 2 (ATP-dependent helicase PRIC285) (Helicase with zinc finger 2, transcriptional coactivator) (PPAR-alpha-interacting complex protein 285) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1) (Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein) (EC 3.6.4.-) Homo sapiens (Human) nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000184; GO:0003677; GO:0003723; GO:0003724; GO:0004540; GO:0005524; GO:0005654; GO:0005737; GO:0016020; GO:0030374; GO:0045944; GO:0046872 32207 FUN_038102 40 355 16 0 112 NA NA NA NA NA NA NA 32208 FUN_038103 5007 2404 1308 5627 3212 NA NA NA NA NA NA NA 32209 FUN_038100 2129 1381 1158 2041 1537 ptg000027l:2336794-2353095 Q25378 9.48e-21 Protein kinase C (EC 2.7.11.13) Lytechinus pictus (Painted sea urchin) protein phosphorylation [GO:0006468] GO:0004698; GO:0005524; GO:0006468; GO:0008270; GO:0106310 32210 FUN_038101 413 208 272 635 431 NA NA NA NA NA NA NA 32211 FUN_021907 10 0 0 0 0 NA NA NA NA NA NA NA 32212 FUN_037909 42917 57516 25124 34043 28164 NA NA NA NA NA NA NA 32213 FUN_037908 728 871 256 670 263 NA NA NA NA NA NA NA 32214 FUN_037903 963 697 537 2840 1029 NA NA NA NA NA NA NA 32215 FUN_037901 1148 739 462 3395 1311 ptg000027l:295410-301126 Q8C753 3.53e-28 Katanin-interacting protein Mus musculus (Mouse) cerebrospinal fluid circulation [GO:0090660] GO:0005576; GO:0005737; GO:0005856; GO:0042995; GO:0090660 32216 FUN_037900 225 127 59 210 239 ptg000027l:291849-293556 Q3USL1 2.57e-31 Kelch domain-containing protein 9 Mus musculus (Mouse) NA GO:0030332 32217 FUN_037907 1692 912 1152 1046 1168 ptg000027l:346104-359791 Q95SX7 4.04e-27 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32218 FUN_037906 778 1450 396 864 812 ptg000027l:337751-345901 Q8BGX0 5.41e-82 E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; protein ubiquitination [GO:0016567]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0004842; GO:0005525; GO:0005634; GO:0005737; GO:0005765; GO:0005886; GO:0006886; GO:0008270; GO:0016192; GO:0016567; GO:0019003; GO:0031401; GO:0042802 32219 FUN_037906 778 1450 396 864 812 ptg000027l:337751-345901 Q8BGX0 1.03e-25 E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23) Mus musculus (Mouse) intracellular protein transport [GO:0006886]; positive regulation of protein modification process [GO:0031401]; protein ubiquitination [GO:0016567]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0003924; GO:0004842; GO:0005525; GO:0005634; GO:0005737; GO:0005765; GO:0005886; GO:0006886; GO:0008270; GO:0016192; GO:0016567; GO:0019003; GO:0031401; GO:0042802 32220 FUN_037905 189 102 78 50 88 NA NA NA NA NA NA NA 32221 FUN_037904 116 55 40 59 22 NA NA NA NA NA NA NA 32222 FUN_041857 1842 1834 868 1563 1075 NA NA NA NA NA NA NA 32223 FUN_014707 16311 20575 15154 16794 9886 NA NA NA NA NA NA NA 32224 FUN_007689 9578 5302 5464 10054 10791 NA NA NA NA NA NA NA 32225 FUN_007688 2138 1257 842 1478 1390 NA NA NA NA NA NA NA 32226 FUN_007683 96 55 57 179 76 ptg000002l:3221659-3222655 Q9MYM7 2.11e-30 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 32227 FUN_007680 210 107 53 86 100 ptg000002l:3191325-3194596 Q9MYM7 6.14e-27 Beta-1,3-galactosyltransferase 1 (Beta-1,3-GalTase 1) (Beta3Gal-T1) (Beta3GalT1) (EC 2.4.1.86) (UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1) Pongo pygmaeus (Bornean orangutan) lipid metabolic process [GO:0006629]; protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0006629; GO:0047275 32228 FUN_007687 29 0 0 0 8 NA NA NA NA NA NA NA 32229 FUN_007686 0 0 0 0 29 NA NA NA NA NA NA NA 32230 FUN_007684 2 13 7 0 0 NA NA NA NA NA NA NA 32231 FUN_001366 3760 2543 747 2160 1452 NA NA NA NA NA NA NA 32232 FUN_041859 3 4 3 0 35 NA NA NA NA NA NA NA 32233 FUN_027504 274 154 87 83 288 NA NA NA NA NA NA NA 32234 FUN_027505 83 85 62 0 75 NA NA NA NA NA NA NA 32235 FUN_027502 2208 1311 606 6 388 NA NA NA NA NA NA NA 32236 FUN_027501 0 0 0 26 0 NA NA NA NA NA NA NA 32237 FUN_027508 1041 1760 1466 512 415 NA NA NA NA NA NA NA 32238 FUN_006087 1182 746 315 747 704 NA NA NA NA NA NA NA 32239 FUN_005269 720 508 358 609 667 NA NA NA NA NA NA NA 32240 FUN_006082 0 8 0 0 0 NA NA NA NA NA NA NA 32241 FUN_006081 8 0 0 0 0 NA NA NA NA NA NA NA 32242 FUN_005262 499 149 156 229 373 ntLink_8:33258301-33269666 Q6PCN7 4.31e-27 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 32243 FUN_005261 0 0 0 2 9 NA NA NA NA NA NA NA 32244 FUN_005260 445 327 250 558 423 ntLink_8:33239042-33252476 Q6PCN7 3.42e-55 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 32245 FUN_005260 445 327 250 558 423 ntLink_8:33239042-33252476 Q6PCN7 3.42e-55 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 32246 FUN_005260 445 327 250 558 423 ntLink_8:33239042-33252476 Q6PCN7 6.34e-26 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 32247 FUN_005260 445 327 250 558 423 ntLink_8:33239042-33252476 Q6PCN7 2.28e-21 Helicase-like transcription factor (EC 2.3.2.27) (EC 3.6.4.-) (P113) (RING-type E3 ubiquitin transferase HLTF) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) Mus musculus (Mouse) DNA repair [GO:0006281]; mRNA transcription by RNA polymerase II [GO:0042789]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of neurogenesis [GO:0050767] GO:0003677; GO:0004386; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006281; GO:0008094; GO:0008270; GO:0016363; GO:0016818; GO:0031625; GO:0042789; GO:0045944; GO:0050767; GO:0061630; GO:0090575; GO:0140658 32248 FUN_005267 4508 4544 3138 7082 2740 NA NA NA NA NA NA NA 32249 FUN_005266 5897 6108 2891 4846 4230 NA NA NA NA NA NA NA 32250 FUN_006088 9 11 4 7 9 NA NA NA NA NA NA NA 32251 FUN_006089 503 461 174 318 198 NA NA NA NA NA NA NA 32252 FUN_016847 0 15 17 102 31 NA NA NA NA NA NA NA 32253 FUN_016846 0 0 0 0 41 NA NA NA NA NA NA NA 32254 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 7.49e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32255 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 6.68e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32256 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 7.11e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32257 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 6.91e-148 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32258 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 1.22e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32259 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 5.45e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32260 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 6.38e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32261 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 4.45e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32262 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 4.77e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32263 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 4.11e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32264 FUN_016844 12 16 0 45 27 ptg000011l:8004176-8012818 Q96AY4 7.04e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32265 FUN_016843 28 7 20 0 17 NA NA NA NA NA NA NA 32266 FUN_016842 0 0 0 0 7 NA NA NA NA NA NA NA 32267 FUN_016840 87 9 0 39 30 NA NA NA NA NA NA NA 32268 FUN_016849 5 8 7 0 0 NA NA NA NA NA NA NA 32269 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 3.72e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32270 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 4.7e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32271 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 2.24e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32272 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 4.09e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32273 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 8.08e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32274 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 4.9e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32275 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 7.05e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32276 FUN_016848 31 21 8 38 16 ptg000011l:8033508-8040915 Q96AY4 5.61e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32277 FUN_037019 28 95 85 154 176 ptg000026l:4636492-4639275 A0JM23 1.02e-46 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 32278 FUN_037019 28 95 85 154 176 ptg000026l:4636492-4639275 A0JM23 2.17e-44 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 32279 FUN_037019 28 95 85 154 176 ptg000026l:4636492-4639275 A0JM23 1.59e-36 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 32280 FUN_037019 28 95 85 154 176 ptg000026l:4636492-4639275 A0JM23 1.07e-35 Nephrocystin-3 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; Wnt signaling pathway [GO:0016055] GO:0005929; GO:0016055; GO:0060271; GO:0090090; GO:2000095 32281 FUN_037018 0 7 0 5 1 ptg000026l:4627405-4629137 Q7Z494 3.3e-39 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 32282 FUN_037018 0 7 0 5 1 ptg000026l:4627405-4629137 Q7Z494 1.9e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 32283 FUN_037018 0 7 0 5 1 ptg000026l:4627405-4629137 Q7Z494 3.09e-30 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 32284 FUN_037011 654 503 258 938 1284 NA NA NA NA NA NA NA 32285 FUN_037010 729 575 345 1038 1083 ptg000026l:4549223-4554416 B2RVL6 2.89e-50 Zinc finger CCHC domain-containing protein 24 Mus musculus (Mouse) NA GO:0003676; GO:0008270 32286 FUN_037013 436 352 450 640 627 NA NA NA NA NA NA NA 32287 FUN_037012 30 0 112 75 8 NA NA NA NA NA NA NA 32288 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 1.99e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32289 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 6.24e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32290 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 1.05e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32291 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 4.25e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32292 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 4.25e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32293 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 5.48e-21 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32294 FUN_037015 344 266 383 650 205 ptg000026l:4589888-4593928 P0CI65 5.48e-21 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 32295 FUN_037014 8 0 54 44 1 NA NA NA NA NA NA NA 32296 FUN_037017 2 0 0 2 34 NA NA NA NA NA NA NA 32297 FUN_037016 2 0 0 2 31 NA NA NA NA NA NA NA 32298 FUN_006559 12 0 3 2 1 NA NA NA NA NA NA NA 32299 FUN_006550 167 511 438 286 282 NA NA NA NA NA NA NA 32300 FUN_006551 213 0 10 78 0 ptg000001l:13946274-13949658 Q95SX7 4.85e-22 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32301 FUN_006552 772 261 431 328 245 NA NA NA NA NA NA NA 32302 FUN_006553 40 247 0 187 185 NA NA NA NA NA NA NA 32303 FUN_006554 43 83 7 253 196 NA NA NA NA NA NA NA 32304 FUN_006556 0 118 7 222 169 NA NA NA NA NA NA NA 32305 FUN_006557 16 15 7 80 89 NA NA NA NA NA NA NA 32306 FUN_032621 4 13 26 28 20 NA NA NA NA NA NA NA 32307 FUN_032620 0 18 0 14 0 NA NA NA NA NA NA NA 32308 FUN_032623 249 128 101 79 83 NA NA NA NA NA NA NA 32309 FUN_032622 42 0 0 0 0 NA NA NA NA NA NA NA 32310 FUN_005199 430 171 210 377 211 ntLink_8:32685788-32699266 Q1LWH4 1.04e-27 Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (Myotubularin-related protein 15) Danio rerio (Zebrafish) (Brachydanio rerio) DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; interstrand cross-link repair [GO:0036297]; nucleotide-excision repair [GO:0006289] GO:0000724; GO:0004528; GO:0005634; GO:0006281; GO:0006289; GO:0008409; GO:0017108; GO:0036297; GO:0046872; GO:0070336; GO:0140036 32311 FUN_005198 366 709 445 753 555 ntLink_8:32674706-32685543 Q7LHG5 1.23e-66 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 32312 FUN_032627 54 0 33 0 135 NA NA NA NA NA NA NA 32313 FUN_032626 1258 20 41 15 316 NA NA NA NA NA NA NA 32314 FUN_032629 1863 1131 384 1503 487 NA NA NA NA NA NA NA 32315 FUN_005194 2103 516 707 2679 352 NA NA NA NA NA NA NA 32316 FUN_005197 619 442 379 796 670 ntLink_8:32659494-32672960 Q9DBT9 1.01e-27 Dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) (ME2GLYDH) Mus musculus (Mouse) amino-acid betaine catabolic process [GO:0006579]; choline catabolic process [GO:0042426]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006579; GO:0016491; GO:0035999; GO:0042426; GO:0047865; GO:0050660 32317 FUN_005197 619 442 379 796 670 ntLink_8:32659494-32672960 Q9DBT9 4.15e-24 Dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) (ME2GLYDH) Mus musculus (Mouse) amino-acid betaine catabolic process [GO:0006579]; choline catabolic process [GO:0042426]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006579; GO:0016491; GO:0035999; GO:0042426; GO:0047865; GO:0050660 32318 FUN_005197 619 442 379 796 670 ntLink_8:32659494-32672960 Q9DBT9 1.33e-22 Dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) (ME2GLYDH) Mus musculus (Mouse) amino-acid betaine catabolic process [GO:0006579]; choline catabolic process [GO:0042426]; tetrahydrofolate interconversion [GO:0035999] GO:0005542; GO:0005737; GO:0005739; GO:0005759; GO:0006579; GO:0016491; GO:0035999; GO:0042426; GO:0047865; GO:0050660 32319 FUN_005196 3 62 32 123 168 NA NA NA NA NA NA NA 32320 FUN_005191 579 151 95 1822 216 NA NA NA NA NA NA NA 32321 FUN_005190 11 20 0 0 0 NA NA NA NA NA NA NA 32322 FUN_005193 175 123 131 732 496 NA NA NA NA NA NA NA 32323 FUN_005192 4 13 12 36 0 NA NA NA NA NA NA NA 32324 FUN_003691 0 0 0 23 13 NA NA NA NA NA NA NA 32325 FUN_003692 2 0 0 34 0 NA NA NA NA NA NA NA 32326 FUN_003693 31504 17017 8446 26177 4508 NA NA NA NA NA NA NA 32327 FUN_003694 7446 3688 1588 2985 792 NA NA NA NA NA NA NA 32328 FUN_003695 2600 1468 768 1598 373 NA NA NA NA NA NA NA 32329 FUN_003696 9866 4466 1584 2682 1620 NA NA NA NA NA NA NA 32330 FUN_003697 12191 5448 1971 3270 1996 NA NA NA NA NA NA NA 32331 FUN_003698 17864 5821 2190 3185 1588 NA NA NA NA NA NA NA 32332 FUN_003699 34236 17396 7324 7850 4165 NA NA NA NA NA NA NA 32333 FUN_002625 13 113 52 52 86 NA NA NA NA NA NA NA 32334 FUN_034662 0 0 13 0 34 NA NA NA NA NA NA NA 32335 FUN_034661 0 4 34 0 20 NA NA NA NA NA NA NA 32336 FUN_034660 1532 232 1752 232 673 NA NA NA NA NA NA NA 32337 FUN_032999 0 35 108 41 31 NA NA NA NA NA NA NA 32338 FUN_002629 0 20 0 30 58 NA NA NA NA NA NA NA 32339 FUN_032993 204763 428912 185437 232261 231974 ptg000023l:38628943-38632808 Q9DG68 2.29e-22 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) Lithobates sylvaticus (Wood frog) (Rana sylvatica) ribosome biogenesis [GO:0042254] GO:0005840; GO:0042254; GO:1990904 32340 FUN_032992 889 607 362 1191 927 NA NA NA NA NA NA NA 32341 FUN_032991 206 82 96 87 143 NA NA NA NA NA NA NA 32342 FUN_032990 211 18 50 1307 135 NA NA NA NA NA NA NA 32343 FUN_032995 0 0 16 0 31 NA NA NA NA NA NA NA 32344 FUN_032994 4346 3398 3055 5902 3962 NA NA NA NA NA NA NA 32345 FUN_008248 4147 2151 2223 2521 1692 NA NA NA NA NA NA NA 32346 FUN_008249 246 273 133 185 308 NA NA NA NA NA NA NA 32347 FUN_034599 3025 3138 1846 4786 4070 ptg000024l:9457247-9474522 A9JRJ2 2e-33 Tectonin beta-propeller repeat-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) autophagosome maturation [GO:0097352]; autophagy [GO:0006914] GO:0000421; GO:0005765; GO:0006914; GO:0031410; GO:0032266; GO:0097352 32348 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 1.96e-52 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32349 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 3.27e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32350 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 7.02e-48 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32351 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 4.21e-47 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32352 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 3.72e-46 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32353 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 2.03e-45 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32354 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 1.58e-41 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32355 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 4.37e-38 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32356 FUN_034598 729 739 466 724 637 ptg000024l:9441229-9447811 Q6ZN57 4.9e-30 Zinc finger protein ZFP2 (Zfp-2) (Zinc finger protein 751) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 32357 FUN_043027 565 270 223 511 471 NA NA NA NA NA NA NA 32358 FUN_034594 294 351 78 182 50 ptg000024l:9401310-9417517 Q09575 2.46e-21 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 32359 FUN_034597 10 0 0 2 0 NA NA NA NA NA NA NA 32360 FUN_034593 0 0 0 0 25 NA NA NA NA NA NA NA 32361 FUN_041979 61 56 19 35 32 NA NA NA NA NA NA NA 32362 FUN_041973 0 15 0 30 0 NA NA NA NA NA NA NA 32363 FUN_041972 86 16 9 116 33 NA NA NA NA NA NA NA 32364 FUN_041971 891 973 292 1053 557 NA NA NA NA NA NA NA 32365 FUN_041970 3317 3628 2099 1888 1136 NA NA NA NA NA NA NA 32366 FUN_041976 0 0 0 8 0 NA NA NA NA NA NA NA 32367 FUN_041975 0 0 0 9 0 NA NA NA NA NA NA NA 32368 FUN_041974 0 0 0 14 0 NA NA NA NA NA NA NA 32369 FUN_001029 378 1037 445 759 440 NA NA NA NA NA NA NA 32370 FUN_001028 625 508 232 510 660 NA NA NA NA NA NA NA 32371 FUN_000032 4 6 17 5 114 NA NA NA NA NA NA NA 32372 FUN_019447 0 0 17 0 4 NA NA NA NA NA NA NA 32373 FUN_001021 241 412 811 725 612 ntLink_6:7307349-7310142 P79218 1.42e-22 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Oryctolagus cuniculus (Rabbit) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0061827; GO:0070472; GO:0097225; GO:1902093 32374 FUN_001020 295 464 285 190 288 NA NA NA NA NA NA NA 32375 FUN_001023 1016 1425 1453 2294 1586 ntLink_6:7320400-7324716 Q96RW7 1.95e-37 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 32376 FUN_001023 1016 1425 1453 2294 1586 ntLink_6:7320400-7324716 Q96RW7 5.25e-35 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 32377 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 2.45e-94 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32378 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 7.48e-87 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32379 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 5.51e-79 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32380 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 2.48e-78 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32381 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 1.05e-75 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32382 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 2.51e-75 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32383 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 1.27e-63 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32384 FUN_001022 645 481 1113 1115 568 ntLink_6:7311491-7317981 Q75N90 9.48e-37 Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653] GO:0001527; GO:0005201; GO:0005509; GO:0005576; GO:0009653; GO:0031012 32385 FUN_001025 8 7 1721 896 759 ntLink_6:7337742-7341989 Q95SX7 6.02e-22 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32386 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 1.48e-54 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32387 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 2.73e-52 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32388 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 1.84e-51 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32389 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 7.24e-51 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32390 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 6.33e-46 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32391 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 1.05e-34 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32392 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 2.65e-32 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32393 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 4.44e-32 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32394 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 9.55e-32 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32395 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 2.79e-31 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32396 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 8.07e-29 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32397 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 3.19e-26 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32398 FUN_001024 661 293 1911 1791 772 ntLink_6:7328391-7333490 P35555 1.15e-25 Fibrillin-1 [Cleaved into: Asprosin] Homo sapiens (Human) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; camera-type eye development [GO:0043010]; cell adhesion mediated by integrin [GO:0033627]; cellular response to insulin-like growth factor stimulus [GO:1990314]; cellular response to transforming growth factor beta stimulus [GO:0071560]; embryonic eye morphogenesis [GO:0048048]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; heart development [GO:0007507]; metanephros development [GO:0001656]; negative regulation of osteoclast development [GO:2001205]; negative regulation of osteoclast differentiation [GO:0045671]; positive regulation of appetite [GO:0032100]; post-embryonic eye morphogenesis [GO:0048050]; protein kinase A signaling [GO:0010737]; sequestering of BMP in extracellular matrix [GO:0035582]; sequestering of TGFbeta in extracellular matrix [GO:0035583]; skeletal system development [GO:0001501] GO:0001501; GO:0001527; GO:0001656; GO:0005178; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005604; GO:0005615; GO:0005788; GO:0006006; GO:0007507; GO:0008201; GO:0009653; GO:0010737; GO:0030023; GO:0031012; GO:0032100; GO:0033627; GO:0034199; GO:0035582; GO:0035583; GO:0042593; GO:0042802; GO:0043010; GO:0044877; GO:0045671; GO:0048048; GO:0048050; GO:0062023; GO:0071560; GO:1990314; GO:2001205 32399 FUN_001027 206 167 337 302 352 NA NA NA NA NA NA NA 32400 FUN_001026 335 375 293 526 549 NA NA NA NA NA NA NA 32401 FUN_019445 0 0 0 0 12 NA NA NA NA NA NA NA 32402 FUN_005045 68 58 23 188 160 NA NA NA NA NA NA NA 32403 FUN_030047 1 7 0 23 0 NA NA NA NA NA NA NA 32404 FUN_005044 149 33 5 98 109 NA NA NA NA NA NA NA 32405 FUN_030046 4633 4320 2353 3112 1994 ptg000023l:8772421-8784902 Q1JPX3 2.41e-22 Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; phenylalanyl-tRNA aminoacylation [GO:0006432]; protein heterotetramerization [GO:0051290] GO:0000049; GO:0000287; GO:0004826; GO:0005524; GO:0005737; GO:0006432; GO:0009328; GO:0048856; GO:0051290 32406 FUN_011018 0 0 7 0 9 NA NA NA NA NA NA NA 32407 FUN_011017 65 0 0 116 16 NA NA NA NA NA NA NA 32408 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 2.19e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32409 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 9.9e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32410 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 1.15e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32411 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 8.14e-51 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32412 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 4.74e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32413 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 3.17e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32414 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 6.33e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32415 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 4.57e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32416 FUN_030044 326 82 344 63 275 ptg000023l:8761343-8766384 Q96AY4 1.79e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32417 FUN_011013 25 84 29 29 83 NA NA NA NA NA NA NA 32418 FUN_026586 567 427 321 337 524 NA NA NA NA NA NA NA 32419 FUN_029249 592 313 271 388 472 NA NA NA NA NA NA NA 32420 FUN_029248 407 312 191 368 291 NA NA NA NA NA NA NA 32421 FUN_029243 687 775 611 874 1029 NA NA NA NA NA NA NA 32422 FUN_029241 2680 2057 1959 1687 1168 NA NA NA NA NA NA NA 32423 FUN_029240 279 178 97 151 127 NA NA NA NA NA NA NA 32424 FUN_000642 3860 3096 2181 3545 3325 NA NA NA NA NA NA NA 32425 FUN_000643 865 258 225 397 461 NA NA NA NA NA NA NA 32426 FUN_000640 172 88 178 108 207 NA NA NA NA NA NA NA 32427 FUN_029244 0 0 16 104 69 NA NA NA NA NA NA NA 32428 FUN_012433 27 24 100 226 45 NA NA NA NA NA NA NA 32429 FUN_012430 7 342 0 251 160 ptg000008l:8877864-8895697 A0A1W5T1T1 4.32e-131 Highly reducing polyketide synthase poxF (HR-PKS poxF) (EC 2.3.1.-) (Oxaleimides biosynthesis cluster protein F) Penicillium oxalicum heterocycle metabolic process [GO:0046483]; organic cyclic compound metabolic process [GO:1901360]; organic substance biosynthetic process [GO:1901576]; secondary metabolite biosynthetic process [GO:0044550] GO:0016491; GO:0016746; GO:0031177; GO:0044550; GO:0046483; GO:1901360; GO:1901576 32430 FUN_012436 5 1881 7 994 933 ptg000008l:8937447-8953209 Q0EEE2 1.41e-34 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 32431 FUN_012436 5 1881 7 994 933 ptg000008l:8937447-8953209 Q0EEE2 3.5e-23 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 32432 FUN_012434 6 558 21 365 68 NA NA NA NA NA NA NA 32433 FUN_012435 0 0 0 4 18 NA NA NA NA NA NA NA 32434 FUN_012439 0 12 0 2 2 NA NA NA NA NA NA NA 32435 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 1.79e-179 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32436 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 9.83e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32437 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 1.36e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32438 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 1.46e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32439 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 3.6e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32440 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 1.7e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32441 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 3.66e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32442 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 4.87e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32443 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 3.77e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32444 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 1.95e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32445 FUN_016542 51 55 67 65 53 ptg000011l:4539198-4546587 Q96AY4 1.03e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32446 FUN_016540 29 110 38 105 88 ptg000011l:4507186-4513067 Q96AY4 1.49e-177 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32447 FUN_016540 29 110 38 105 88 ptg000011l:4507186-4513067 Q96AY4 8.27e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32448 FUN_016540 29 110 38 105 88 ptg000011l:4507186-4513067 Q96AY4 1.22e-158 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32449 FUN_016540 29 110 38 105 88 ptg000011l:4507186-4513067 Q96AY4 2.02e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32450 FUN_016540 29 110 38 105 88 ptg000011l:4507186-4513067 Q96AY4 5.63e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32451 FUN_016547 83 117 60 68 73 ptg000011l:4573318-4577605 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32452 FUN_016547 83 117 60 68 73 ptg000011l:4573318-4577605 Q96AY4 4.44e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32453 FUN_016547 83 117 60 68 73 ptg000011l:4573318-4577605 Q96AY4 1.14e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32454 FUN_016547 83 117 60 68 73 ptg000011l:4573318-4577605 Q96AY4 7.66e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32455 FUN_016547 83 117 60 68 73 ptg000011l:4573318-4577605 Q96AY4 2.07e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32456 FUN_016544 0 0 41 16 45 NA NA NA NA NA NA NA 32457 FUN_016549 114 63 29 139 73 ptg000011l:4596649-4601165 Q96AY4 7.75e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32458 FUN_016549 114 63 29 139 73 ptg000011l:4596649-4601165 Q96AY4 8.23e-143 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32459 FUN_016549 114 63 29 139 73 ptg000011l:4596649-4601165 Q96AY4 5.13e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32460 FUN_016549 114 63 29 139 73 ptg000011l:4596649-4601165 Q96AY4 5.84e-98 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32461 FUN_016549 114 63 29 139 73 ptg000011l:4596649-4601165 Q96AY4 9.99e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32462 FUN_016549 114 63 29 139 73 ptg000011l:4596649-4601165 Q96AY4 2.82e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32463 FUN_013525 689 3539 1614 2751 115 ptg000008l:23698015-23706857 Q7RTR2 8.02e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32464 FUN_013525 689 3539 1614 2751 115 ptg000008l:23698015-23706857 Q7RTR2 3.08e-54 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32465 FUN_013525 689 3539 1614 2751 115 ptg000008l:23698015-23706857 Q7RTR2 1.17e-51 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32466 FUN_013525 689 3539 1614 2751 115 ptg000008l:23698015-23706857 Q7RTR2 3.29e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32467 FUN_013525 689 3539 1614 2751 115 ptg000008l:23698015-23706857 Q7RTR2 6.76e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32468 FUN_013525 689 3539 1614 2751 115 ptg000008l:23698015-23706857 Q7RTR2 9.3e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32469 FUN_013524 0 32 0 35 3 NA NA NA NA NA NA NA 32470 FUN_013523 0 0 0 0 43 NA NA NA NA NA NA NA 32471 FUN_013520 497 1015 709 320 160 ptg000008l:23647585-23652991 Q99570 6.02e-32 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 32472 FUN_013520 497 1015 709 320 160 ptg000008l:23647585-23652991 Q99570 1.97e-31 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 32473 FUN_013529 0 49 0 0 60 NA NA NA NA NA NA NA 32474 FUN_013528 44 59 127 102 76 NA NA NA NA NA NA NA 32475 FUN_010874 486 591 294 606 680 ptg000007l:3772225-3781992 Q5M8I4 5.52e-21 EARP-interacting protein homolog Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) endocytic recycling [GO:0032456] GO:0005794; GO:0032456 32476 FUN_010875 1198 796 641 906 2001 NA NA NA NA NA NA NA 32477 FUN_010876 162 67 66 18 107 NA NA NA NA NA NA NA 32478 FUN_010870 0 0 0 0 8 NA NA NA NA NA NA NA 32479 FUN_043606 0 11 0 9 0 NA NA NA NA NA NA NA 32480 FUN_010873 6 0 31 6 32 NA NA NA NA NA NA NA 32481 FUN_043609 1519 742 1656 3551 2160 ptg000047l:10673969-10753691 Q99315 2.26e-71 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 32482 FUN_043608 166 335 111 91 89 ptg000047l:10669252-10670032 Q5TZ07 1.61e-33 Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (EC 3.1.3.-) (EC 3.6.1.-) (EC 3.6.1.68) (Phosphatidic acid phosphatase type 2 domain-containing protein 2) (Phospholipid phosphatase 6) Danio rerio (Zebrafish) (Brachydanio rerio) farnesyl diphosphate catabolic process [GO:0045339]; geranyl diphosphate metabolic process [GO:0033383]; geranylgeranyl diphosphate catabolic process [GO:1902247]; phospholipid dephosphorylation [GO:0046839]; protein prenylation [GO:0018342] GO:0005637; GO:0005789; GO:0016020; GO:0018342; GO:0031965; GO:0033383; GO:0042392; GO:0045339; GO:0046839; GO:1902247 32483 FUN_010878 1255 1340 678 1669 852 ptg000007l:3817644-3820005 Q8R164 5.95e-29 Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) Mus musculus (Mouse) NA GO:0005739; GO:0047658 32484 FUN_010878 1255 1340 678 1669 852 ptg000007l:3817644-3820005 Q8R164 5.35e-25 Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) Mus musculus (Mouse) NA GO:0005739; GO:0047658 32485 FUN_010879 5157 4278 2429 3800 3221 NA NA NA NA NA NA NA 32486 FUN_016094 331 497 84 230 73 NA NA NA NA NA NA NA 32487 FUN_028199 47 22 41 16 66 NA NA NA NA NA NA NA 32488 FUN_016096 0 0 0 22 0 NA NA NA NA NA NA NA 32489 FUN_016097 645 702 163 395 404 NA NA NA NA NA NA NA 32490 FUN_016090 553 383 231 373 352 NA NA NA NA NA NA NA 32491 FUN_016091 3655 2976 1427 2854 2250 ptg000010l:1488728-1495335 P63086 7.17e-37 Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) Rattus norvegicus (Rat) aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neural crest cell development [GO:0014032]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440] GO:0000165; GO:0001784; GO:0003690; GO:0004672; GO:0004674; GO:0004707; GO:0004708; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005769; GO:0005770; GO:0005794; GO:0005815; GO:0005829; GO:0005856; GO:0005886; GO:0005901; GO:0005925; GO:0006468; GO:0006915; GO:0006974; GO:0007049; GO:0007165; GO:0007166; GO:0007507; GO:0007568; GO:0008284; GO:0008286; GO:0008353; GO:0009636; GO:0009887; GO:0010628; GO:0010759; GO:0010800; GO:0014032; GO:0014069; GO:0015966; GO:0016301; GO:0018105; GO:0018107; GO:0019233; GO:0019858; GO:0019901; GO:0019902; GO:0030278; GO:0030335; GO:0030424; GO:0030641; GO:0030878; GO:0031143; GO:0031435; GO:0031647; GO:0031663; GO:0032212; GO:0032496; GO:0032839; GO:0032872; GO:0032991; GO:0033598; GO:0034198; GO:0034614; GO:0035094; GO:0035556; GO:0038127; GO:0042307; GO:0042473; GO:0042802; GO:0043204; GO:0043330; GO:0043627; GO:0045596; GO:0045727; GO:0045893; GO:0046697; GO:0048009; GO:0048538; GO:0050852; GO:0050853; GO:0051403; GO:0051493; GO:0051973; GO:0060020; GO:0060045; GO:0060291; GO:0060324; GO:0060425; GO:0060440; GO:0060716; GO:0061308; GO:0070371; GO:0070849; GO:0071276; GO:0071310; GO:0071356; GO:0072584; GO:0072686; GO:0090170; GO:0097011; GO:0106310; GO:0120041; GO:1903351; GO:1904355; GO:2000641 32492 FUN_016091 3655 2976 1427 2854 2250 ptg000010l:1488728-1495335 P63086 4.91e-30 Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) Rattus norvegicus (Rat) aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neural crest cell development [GO:0014032]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440] GO:0000165; GO:0001784; GO:0003690; GO:0004672; GO:0004674; GO:0004707; GO:0004708; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005769; GO:0005770; GO:0005794; GO:0005815; GO:0005829; GO:0005856; GO:0005886; GO:0005901; GO:0005925; GO:0006468; GO:0006915; GO:0006974; GO:0007049; GO:0007165; GO:0007166; GO:0007507; GO:0007568; GO:0008284; GO:0008286; GO:0008353; GO:0009636; GO:0009887; GO:0010628; GO:0010759; GO:0010800; GO:0014032; GO:0014069; GO:0015966; GO:0016301; GO:0018105; GO:0018107; GO:0019233; GO:0019858; GO:0019901; GO:0019902; GO:0030278; GO:0030335; GO:0030424; GO:0030641; GO:0030878; GO:0031143; GO:0031435; GO:0031647; GO:0031663; GO:0032212; GO:0032496; GO:0032839; GO:0032872; GO:0032991; GO:0033598; GO:0034198; GO:0034614; GO:0035094; GO:0035556; GO:0038127; GO:0042307; GO:0042473; GO:0042802; GO:0043204; GO:0043330; GO:0043627; GO:0045596; GO:0045727; GO:0045893; GO:0046697; GO:0048009; GO:0048538; GO:0050852; GO:0050853; GO:0051403; GO:0051493; GO:0051973; GO:0060020; GO:0060045; GO:0060291; GO:0060324; GO:0060425; GO:0060440; GO:0060716; GO:0061308; GO:0070371; GO:0070849; GO:0071276; GO:0071310; GO:0071356; GO:0072584; GO:0072686; GO:0090170; GO:0097011; GO:0106310; GO:0120041; GO:1903351; GO:1904355; GO:2000641 32493 FUN_016091 3655 2976 1427 2854 2250 ptg000010l:1488728-1495335 P63086 6.22e-25 Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) Rattus norvegicus (Rat) aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neural crest cell development [GO:0014032]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440] GO:0000165; GO:0001784; GO:0003690; GO:0004672; GO:0004674; GO:0004707; GO:0004708; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005769; GO:0005770; GO:0005794; GO:0005815; GO:0005829; GO:0005856; GO:0005886; GO:0005901; GO:0005925; GO:0006468; GO:0006915; GO:0006974; GO:0007049; GO:0007165; GO:0007166; GO:0007507; GO:0007568; GO:0008284; GO:0008286; GO:0008353; GO:0009636; GO:0009887; GO:0010628; GO:0010759; GO:0010800; GO:0014032; GO:0014069; GO:0015966; GO:0016301; GO:0018105; GO:0018107; GO:0019233; GO:0019858; GO:0019901; GO:0019902; GO:0030278; GO:0030335; GO:0030424; GO:0030641; GO:0030878; GO:0031143; GO:0031435; GO:0031647; GO:0031663; GO:0032212; GO:0032496; GO:0032839; GO:0032872; GO:0032991; GO:0033598; GO:0034198; GO:0034614; GO:0035094; GO:0035556; GO:0038127; GO:0042307; GO:0042473; GO:0042802; GO:0043204; GO:0043330; GO:0043627; GO:0045596; GO:0045727; GO:0045893; GO:0046697; GO:0048009; GO:0048538; GO:0050852; GO:0050853; GO:0051403; GO:0051493; GO:0051973; GO:0060020; GO:0060045; GO:0060291; GO:0060324; GO:0060425; GO:0060440; GO:0060716; GO:0061308; GO:0070371; GO:0070849; GO:0071276; GO:0071310; GO:0071356; GO:0072584; GO:0072686; GO:0090170; GO:0097011; GO:0106310; GO:0120041; GO:1903351; GO:1904355; GO:2000641 32494 FUN_016091 3655 2976 1427 2854 2250 ptg000010l:1488728-1495335 P63086 6.22e-25 Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) Rattus norvegicus (Rat) aging [GO:0007568]; animal organ morphogenesis [GO:0009887]; apoptotic process [GO:0006915]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cardiac neural crest cell development involved in heart development [GO:0061308]; caveolin-mediated endocytosis [GO:0072584]; cell cycle [GO:0007049]; cell surface receptor signaling pathway [GO:0007166]; cellular response to amino acid starvation [GO:0034198]; cellular response to cadmium ion [GO:0071276]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to organic substance [GO:0071310]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; cytosine metabolic process [GO:0019858]; decidualization [GO:0046697]; diadenosine tetraphosphate biosynthetic process [GO:0015966]; ERBB signaling pathway [GO:0038127]; ERK1 and ERK2 cascade [GO:0070371]; face development [GO:0060324]; heart development [GO:0007507]; insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009]; intracellular signal transduction [GO:0035556]; labyrinthine layer blood vessel development [GO:0060716]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; long-term synaptic potentiation [GO:0060291]; lung morphogenesis [GO:0060425]; mammary gland epithelial cell proliferation [GO:0033598]; MAPK cascade [GO:0000165]; negative regulation of cell differentiation [GO:0045596]; neural crest cell development [GO:0014032]; outer ear morphogenesis [GO:0042473]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cardiac muscle cell proliferation [GO:0060045]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of macrophage chemotaxis [GO:0010759]; positive regulation of macrophage proliferation [GO:0120041]; positive regulation of peptidyl-threonine phosphorylation [GO:0010800]; positive regulation of protein import into nucleus [GO:0042307]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; positive regulation of translation [GO:0045727]; protein phosphorylation [GO:0006468]; regulation of cellular pH [GO:0030641]; regulation of cytoskeleton organization [GO:0051493]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of Golgi inheritance [GO:0090170]; regulation of ossification [GO:0030278]; regulation of protein stability [GO:0031647]; regulation of stress-activated MAPK cascade [GO:0032872]; response to epidermal growth factor [GO:0070849]; response to estrogen [GO:0043627]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to nicotine [GO:0035094]; response to toxic substance [GO:0009636]; sensory perception of pain [GO:0019233]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; thyroid gland development [GO:0030878]; trachea formation [GO:0060440] GO:0000165; GO:0001784; GO:0003690; GO:0004672; GO:0004674; GO:0004707; GO:0004708; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005769; GO:0005770; GO:0005794; GO:0005815; GO:0005829; GO:0005856; GO:0005886; GO:0005901; GO:0005925; GO:0006468; GO:0006915; GO:0006974; GO:0007049; GO:0007165; GO:0007166; GO:0007507; GO:0007568; GO:0008284; GO:0008286; GO:0008353; GO:0009636; GO:0009887; GO:0010628; GO:0010759; GO:0010800; GO:0014032; GO:0014069; GO:0015966; GO:0016301; GO:0018105; GO:0018107; GO:0019233; GO:0019858; GO:0019901; GO:0019902; GO:0030278; GO:0030335; GO:0030424; GO:0030641; GO:0030878; GO:0031143; GO:0031435; GO:0031647; GO:0031663; GO:0032212; GO:0032496; GO:0032839; GO:0032872; GO:0032991; GO:0033598; GO:0034198; GO:0034614; GO:0035094; GO:0035556; GO:0038127; GO:0042307; GO:0042473; GO:0042802; GO:0043204; GO:0043330; GO:0043627; GO:0045596; GO:0045727; GO:0045893; GO:0046697; GO:0048009; GO:0048538; GO:0050852; GO:0050853; GO:0051403; GO:0051493; GO:0051973; GO:0060020; GO:0060045; GO:0060291; GO:0060324; GO:0060425; GO:0060440; GO:0060716; GO:0061308; GO:0070371; GO:0070849; GO:0071276; GO:0071310; GO:0071356; GO:0072584; GO:0072686; GO:0090170; GO:0097011; GO:0106310; GO:0120041; GO:1903351; GO:1904355; GO:2000641 32495 FUN_016092 21 58 33 33 28 ptg000010l:1502618-1503641 Q9TTM9 4.22e-22 Alpha-1D adrenergic receptor (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) Sus scrofa (Pig) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 32496 FUN_016093 109 138 43 25 134 ptg000010l:1527323-1529995 F1RB95 3.18e-46 NA NA NA NA 32497 FUN_028190 35350 41965 19973 39599 31631 ptg000021l:16720623-16741234 B8VIW9 7.68e-23 Fibronectin type III domain-containing protein (Neuroglian-like protein) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0016020 32498 FUN_028191 1272 1475 294 1518 836 NA NA NA NA NA NA NA 32499 FUN_028192 1336 1487 687 1164 1128 NA NA NA NA NA NA NA 32500 FUN_028193 3962 2796 1982 2284 2386 NA NA NA NA NA NA NA 32501 FUN_016098 235 162 118 225 67 ptg000010l:1557466-1561043 Q8K2J9 2.3e-63 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 32502 FUN_016099 264 72 90 207 149 ptg000010l:1561172-1562534 Q8K2J9 3.89e-82 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 32503 FUN_028196 33 0 0 41 43 NA NA NA NA NA NA NA 32504 FUN_028197 0 0 0 25 0 NA NA NA NA NA NA NA 32505 FUN_011683 971 625 716 684 985 NA NA NA NA NA NA NA 32506 FUN_008794 1425 1347 750 1031 957 ptg000002l:15693934-15697910 Q9FZ48 7.57e-34 Ubiquitin-conjugating enzyme E2 36 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 36) (Ubiquitin carrier protein 36) Arabidopsis thaliana (Mouse-ear cress) postreplication repair [GO:0006301]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0005524; GO:0005634; GO:0006301; GO:0061631; GO:0070534 32507 FUN_008795 234 131 615 427 116 ptg000002l:15700993-15707881 Q9BH05 8.24e-37 Threonine synthase-like 1 (TSH1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 32508 FUN_008795 234 131 615 427 116 ptg000002l:15700993-15707881 Q9BH05 2.72e-23 Threonine synthase-like 1 (TSH1) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA NA 32509 FUN_008927 1766 2464 2173 2736 2304 ptg000004l:586026-588397 Q6P268 7.65e-28 Phosducin-like protein 3 (Viral IAP-associated factor 1 homolog) Danio rerio (Zebrafish) (Brachydanio rerio) angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; positive regulation of gene expression [GO:0010628]; protein folding [GO:0006457] GO:0001525; GO:0005737; GO:0005783; GO:0006457; GO:0006915; GO:0010628; GO:0043184; GO:0044183; GO:0048471 32510 FUN_008926 569 435 337 569 575 NA NA NA NA NA NA NA 32511 FUN_008925 1903 2043 1205 1486 1128 NA NA NA NA NA NA NA 32512 FUN_008924 86752 114469 59567 67986 42816 NA NA NA NA NA NA NA 32513 FUN_008923 435 417 372 265 607 NA NA NA NA NA NA NA 32514 FUN_008922 56 27 65 17 235 NA NA NA NA NA NA NA 32515 FUN_008921 17764 16065 7974 14814 9221 NA NA NA NA NA NA NA 32516 FUN_008920 1410 778 660 925 868 NA NA NA NA NA NA NA 32517 FUN_008929 63 8 6 6 26 NA NA NA NA NA NA NA 32518 FUN_008928 85 97 48 109 116 NA NA NA NA NA NA NA 32519 FUN_013383 3426 2616 1946 3399 2789 ptg000008l:21892996-21898392 F7CYY5 2.59e-57 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005829; GO:0006177; GO:0006183; GO:0046872 32520 FUN_013383 3426 2616 1946 3399 2789 ptg000008l:21892996-21898392 F7CYY5 6.06e-39 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005829; GO:0006177; GO:0006183; GO:0046872 32521 FUN_013383 3426 2616 1946 3399 2789 ptg000008l:21892996-21898392 F7CYY5 1.92e-37 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005829; GO:0006177; GO:0006183; GO:0046872 32522 FUN_013383 3426 2616 1946 3399 2789 ptg000008l:21892996-21898392 F7CYY5 1.62e-35 Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) GMP biosynthetic process [GO:0006177]; GTP biosynthetic process [GO:0006183] GO:0000166; GO:0003938; GO:0005634; GO:0005829; GO:0006177; GO:0006183; GO:0046872 32523 FUN_023671 1231 2252 881 6165 2808 NA NA NA NA NA NA NA 32524 FUN_023672 2013 2392 1027 1909 1873 NA NA NA NA NA NA NA 32525 FUN_023673 89 19 6 32 15 NA NA NA NA NA NA NA 32526 FUN_013387 2734 1593 1554 2487 2031 ptg000008l:21922118-21954628 Q3UY96 5.93e-26 Cilia- and flagella-associated protein 74 Mus musculus (Mouse) axoneme assembly [GO:0035082] GO:0005930; GO:0035082 32527 FUN_013386 85 80 88 441 141 NA NA NA NA NA NA NA 32528 FUN_023676 2973 2267 1445 3451 2027 ptg000017l:10545638-10548340 Q02083 1.12e-27 N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.60) (Acid ceramidase-like protein) (Acylsphingosine deacylase NAAA) (EC 3.5.1.23) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta] Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; sphingosine metabolic process [GO:0006670] GO:0005737; GO:0005764; GO:0006631; GO:0006670; GO:0016042; GO:0016810; GO:0017040; GO:0017064; GO:0019898; GO:0043202; GO:0047412; GO:0070062; GO:0070291; GO:0070292; GO:0102121; GO:0140297 32529 FUN_023676 2973 2267 1445 3451 2027 ptg000017l:10545638-10548340 Q02083 1.64e-24 N-acylethanolamine-hydrolyzing acid amidase (EC 3.5.1.60) (Acid ceramidase-like protein) (Acylsphingosine deacylase NAAA) (EC 3.5.1.23) (N-acylsphingosine amidohydrolase-like) (ASAH-like protein) [Cleaved into: N-acylethanolamine-hydrolyzing acid amidase subunit alpha; N-acylethanolamine-hydrolyzing acid amidase subunit beta] Homo sapiens (Human) fatty acid metabolic process [GO:0006631]; lipid catabolic process [GO:0016042]; N-acylethanolamine metabolic process [GO:0070291]; N-acylphosphatidylethanolamine metabolic process [GO:0070292]; sphingosine metabolic process [GO:0006670] GO:0005737; GO:0005764; GO:0006631; GO:0006670; GO:0016042; GO:0016810; GO:0017040; GO:0017064; GO:0019898; GO:0043202; GO:0047412; GO:0070062; GO:0070291; GO:0070292; GO:0102121; GO:0140297 32530 FUN_013384 4416 4690 5115 24149 13102 NA NA NA NA NA NA NA 32531 FUN_023679 7 5 32 33 68 NA NA NA NA NA NA NA 32532 FUN_013389 1112 481 962 657 970 NA NA NA NA NA NA NA 32533 FUN_013388 1623 1447 848 1774 2493 NA NA NA NA NA NA NA 32534 FUN_032845 0 0 0 14 0 NA NA NA NA NA NA NA 32535 FUN_019442 2 0 20 0 136 NA NA NA NA NA NA NA 32536 FUN_041577 401 183 139 266 170 NA NA NA NA NA NA NA 32537 FUN_041116 0 15 3 6 0 NA NA NA NA NA NA NA 32538 FUN_041110 0 0 0 0 31 ptg000034l:730555-733617 P84239 3.42e-83 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32539 FUN_041112 6 0 0 2 19 NA NA NA NA NA NA NA 32540 FUN_009032 17 5 0 12 29 NA NA NA NA NA NA NA 32541 FUN_009033 0 7 0 0 35 NA NA NA NA NA NA NA 32542 FUN_009030 19 0 0 0 0 NA NA NA NA NA NA NA 32543 FUN_009031 0 2 0 16 0 NA NA NA NA NA NA NA 32544 FUN_009036 0 0 0 0 24 NA NA NA NA NA NA NA 32545 FUN_009037 293 392 109 273 191 NA NA NA NA NA NA NA 32546 FUN_009034 0 0 0 0 17 NA NA NA NA NA NA NA 32547 FUN_009035 3327 2202 1345 3051 2458 NA NA NA NA NA NA NA 32548 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 1.21e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32549 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 6.89e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32550 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 4.96e-94 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32551 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 2.94e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32552 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 3.33e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32553 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 1.27e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32554 FUN_041573 476 320 437 476 344 ptg000035l:5406260-5416927 Q96AY4 9.26e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32555 FUN_009038 134 38 87 29 174 NA NA NA NA NA NA NA 32556 FUN_009039 592 312 115 260 330 NA NA NA NA NA NA NA 32557 FUN_011839 0 0 81 29 0 NA NA NA NA NA NA NA 32558 FUN_011838 229 88 291 149 168 ptg000008l:1966691-1978723 E9Q5R7 4.19e-35 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 32559 FUN_011837 712 296 552 387 692 NA NA NA NA NA NA NA 32560 FUN_011836 60 79 113 0 75 ptg000008l:1919216-1954626 P59046 4.89e-52 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 32561 FUN_011835 117 149 590 185 252 ptg000008l:1903300-1906769 Q7RTR2 8.78e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32562 FUN_011834 78 49 96 44 108 NA NA NA NA NA NA NA 32563 FUN_011833 105 196 160 139 285 NA NA NA NA NA NA NA 32564 FUN_011832 19 2 40 0 177 NA NA NA NA NA NA NA 32565 FUN_025737 906 361 418 717 828 NA NA NA NA NA NA NA 32566 FUN_025736 786 395 266 426 536 NA NA NA NA NA NA NA 32567 FUN_025735 7 8 4 8 9 NA NA NA NA NA NA NA 32568 FUN_022102 21 36 0 0 20 NA NA NA NA NA NA NA 32569 FUN_022105 139 101 77 150 120 NA NA NA NA NA NA NA 32570 FUN_022104 983 614 927 879 980 ptg000016l:5446970-5468205 A0A0R4IXF6 2.91e-46 Histone acetyltransferase KAT2A (EC 2.3.1.48) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) Danio rerio (Zebrafish) (Brachydanio rerio) bone morphogenesis [GO:0060349]; chromatin remodeling [GO:0006338]; heart development [GO:0007507]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; histone succinylation [GO:0106077]; internal peptidyl-lysine acetylation [GO:0018393]; limb development [GO:0060173]; long-term memory [GO:0007616]; peptidyl-lysine glutarylation [GO:0106227]; positive regulation of cytokine production [GO:0001819]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of bone development [GO:1903010]; regulation of cartilage development [GO:0061035]; regulation of regulatory T cell differentiation [GO:0045589]; regulation of synaptic plasticity [GO:0048167]; regulation of T cell activation [GO:0050863] GO:0000123; GO:0001819; GO:0003682; GO:0003713; GO:0004402; GO:0005634; GO:0005737; GO:0005813; GO:0006338; GO:0007507; GO:0007616; GO:0010484; GO:0018393; GO:0043966; GO:0043992; GO:0044154; GO:0045589; GO:0045893; GO:0045944; GO:0048167; GO:0050863; GO:0060173; GO:0060349; GO:0061035; GO:0061733; GO:0106077; GO:0106078; GO:0106227; GO:0106229; GO:0140672; GO:1903010 32571 FUN_022107 768 481 605 1093 868 NA NA NA NA NA NA NA 32572 FUN_022106 2348 1931 1506 5431 3295 NA NA NA NA NA NA NA 32573 FUN_022109 2105 1666 1520 7453 6165 NA NA NA NA NA NA NA 32574 FUN_022108 2099 1553 1635 3429 2227 NA NA NA NA NA NA NA 32575 FUN_041578 1623 1462 1020 2065 2454 ptg000035l:5443460-5464080 Q80YF9 6.6e-26 Rho GTPase-activating protein 33 (Rho-type GTPase-activating protein 33) (Sorting nexin-26) (Tc10/CDC42 GTPase-activating protein) Mus musculus (Mouse) protein transport [GO:0015031]; regulation of dendritic spine morphogenesis [GO:0061001]; response to toxic substance [GO:0009636]; small GTPase mediated signal transduction [GO:0007264] GO:0005096; GO:0005737; GO:0005886; GO:0007264; GO:0009636; GO:0015031; GO:0019901; GO:0032991; GO:0035091; GO:0043197; GO:0061001 32576 FUN_025815 12 413 0 264 5 NA NA NA NA NA NA NA 32577 FUN_025739 1 2 6 0 3 NA NA NA NA NA NA NA 32578 FUN_025738 220 168 29 55 32 NA NA NA NA NA NA NA 32579 FUN_008075 3418 870 1418 1727 1903 NA NA NA NA NA NA NA 32580 FUN_008074 130 87 29 317 132 NA NA NA NA NA NA NA 32581 FUN_024466 256 160 173 47 51 NA NA NA NA NA NA NA 32582 FUN_009551 0 0 0 0 62 NA NA NA NA NA NA NA 32583 FUN_024460 2672 1861 1649 2590 1665 ptg000018l:6620271-6640905 Q2M389 2.65e-37 WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; nuclear envelope budding [GO:0140591]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0005654; GO:0005768; GO:0007032; GO:0015031; GO:0016197; GO:0031901; GO:0034315; GO:0071203; GO:0140591 32584 FUN_024460 2672 1861 1649 2590 1665 ptg000018l:6620271-6640905 Q2M389 2.24e-31 WASH complex subunit 4 (Strumpellin and WASH-interacting protein) (SWIP) (WASH complex subunit SWIP) Homo sapiens (Human) endosomal transport [GO:0016197]; endosome organization [GO:0007032]; nuclear envelope budding [GO:0140591]; protein transport [GO:0015031]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315] GO:0005654; GO:0005768; GO:0007032; GO:0015031; GO:0016197; GO:0031901; GO:0034315; GO:0071203; GO:0140591 32585 FUN_024461 2723 2001 826 4393 4223 NA NA NA NA NA NA NA 32586 FUN_024463 1441 107 1134 792 723 ptg000018l:6665858-6673246 Q96AY4 1.14e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32587 FUN_024463 1441 107 1134 792 723 ptg000018l:6665858-6673246 Q96AY4 1.87e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32588 FUN_008079 7916 3785 3684 6226 5931 ptg000002l:7751260-7778213 A6H5Y3 2.27e-23 Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) Mus musculus (Mouse) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; protein methylation [GO:0006479]; response to axon injury [GO:0048678]; tetrahydrofolate metabolic process [GO:0046653] GO:0005542; GO:0005829; GO:0006479; GO:0006555; GO:0008168; GO:0008270; GO:0008705; GO:0009086; GO:0009235; GO:0016597; GO:0031103; GO:0031419; GO:0046653; GO:0048678; GO:0050667; GO:0071732 32589 FUN_008079 7916 3785 3684 6226 5931 ptg000002l:7751260-7778213 A6H5Y3 3.82e-22 Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) Mus musculus (Mouse) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; protein methylation [GO:0006479]; response to axon injury [GO:0048678]; tetrahydrofolate metabolic process [GO:0046653] GO:0005542; GO:0005829; GO:0006479; GO:0006555; GO:0008168; GO:0008270; GO:0008705; GO:0009086; GO:0009235; GO:0016597; GO:0031103; GO:0031419; GO:0046653; GO:0048678; GO:0050667; GO:0071732 32590 FUN_008079 7916 3785 3684 6226 5931 ptg000002l:7751260-7778213 A6H5Y3 1.05e-21 Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) Mus musculus (Mouse) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; protein methylation [GO:0006479]; response to axon injury [GO:0048678]; tetrahydrofolate metabolic process [GO:0046653] GO:0005542; GO:0005829; GO:0006479; GO:0006555; GO:0008168; GO:0008270; GO:0008705; GO:0009086; GO:0009235; GO:0016597; GO:0031103; GO:0031419; GO:0046653; GO:0048678; GO:0050667; GO:0071732 32591 FUN_008079 7916 3785 3684 6226 5931 ptg000002l:7751260-7778213 A6H5Y3 1.05e-21 Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) Mus musculus (Mouse) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; protein methylation [GO:0006479]; response to axon injury [GO:0048678]; tetrahydrofolate metabolic process [GO:0046653] GO:0005542; GO:0005829; GO:0006479; GO:0006555; GO:0008168; GO:0008270; GO:0008705; GO:0009086; GO:0009235; GO:0016597; GO:0031103; GO:0031419; GO:0046653; GO:0048678; GO:0050667; GO:0071732 32592 FUN_008079 7916 3785 3684 6226 5931 ptg000002l:7751260-7778213 A6H5Y3 2.84e-21 Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase) Mus musculus (Mouse) axon regeneration [GO:0031103]; cellular response to nitric oxide [GO:0071732]; cobalamin metabolic process [GO:0009235]; homocysteine metabolic process [GO:0050667]; methionine biosynthetic process [GO:0009086]; methionine metabolic process [GO:0006555]; protein methylation [GO:0006479]; response to axon injury [GO:0048678]; tetrahydrofolate metabolic process [GO:0046653] GO:0005542; GO:0005829; GO:0006479; GO:0006555; GO:0008168; GO:0008270; GO:0008705; GO:0009086; GO:0009235; GO:0016597; GO:0031103; GO:0031419; GO:0046653; GO:0048678; GO:0050667; GO:0071732 32593 FUN_008078 762 682 401 457 281 ptg000002l:7747863-7748274 Q9VBW0 1.46e-21 NA NA NA NA 32594 FUN_010122 250 109 102 163 86 NA NA NA NA NA NA NA 32595 FUN_040643 0 0 13 0 0 NA NA NA NA NA NA NA 32596 FUN_040641 47 4 38 3 177 NA NA NA NA NA NA NA 32597 FUN_010126 2 0 9 14 154 NA NA NA NA NA NA NA 32598 FUN_040644 32 0 0 0 0 NA NA NA NA NA NA NA 32599 FUN_010125 0 0 0 0 6 ptg000004l:14589669-14590248 Q80TC5 7.25e-21 Pogo transposable element with KRAB domain Mus musculus (Mouse) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 32600 FUN_014926 782 976 240 562 491 ptg000009l:4405980-4406872 Q1KZG4 1.76e-51 Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Adenosine 5'-monophosphoramidase FHIT) (EC 3.9.1.-) (Adenylylsulfatase) (EC 3.6.2.1) (Adenylylsulfate-ammonia adenylyltransferase) (EC 2.7.7.51) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein) Bos taurus (Bovine) diadenosine triphosphate catabolic process [GO:0015964]; intrinsic apoptotic signaling pathway by p53 class mediator [GO:0072332]; negative regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032435]; purine nucleotide metabolic process [GO:0006163] GO:0000166; GO:0001650; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006163; GO:0015964; GO:0031625; GO:0032435; GO:0042802; GO:0043530; GO:0047352; GO:0047627; GO:0047710; GO:0072332 32601 FUN_014927 4713 2196 4260 5457 3015 ptg000009l:4408193-4417640 Q04336 1.83e-25 Uncharacterized protein YMR196W Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) oligosaccharide metabolic process [GO:0009311] GO:0004573; GO:0005737; GO:0009311 32602 FUN_014927 4713 2196 4260 5457 3015 ptg000009l:4408193-4417640 Q04336 4.63e-23 Uncharacterized protein YMR196W Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) oligosaccharide metabolic process [GO:0009311] GO:0004573; GO:0005737; GO:0009311 32603 FUN_014924 1196 523 736 1118 898 NA NA NA NA NA NA NA 32604 FUN_014925 5746 3739 2777 4958 4237 NA NA NA NA NA NA NA 32605 FUN_014922 425 209 209 245 512 NA NA NA NA NA NA NA 32606 FUN_014920 41 142 97 23 38 NA NA NA NA NA NA NA 32607 FUN_014921 78 45 43 188 148 NA NA NA NA NA NA NA 32608 FUN_014928 1875 1149 781 1038 700 NA NA NA NA NA NA NA 32609 FUN_038744 764 488 275 647 419 NA NA NA NA NA NA NA 32610 FUN_038745 32 20 8 0 9 NA NA NA NA NA NA NA 32611 FUN_015039 377 1546 919 2551 2150 NA NA NA NA NA NA NA 32612 FUN_015038 3288 2129 1487 1879 1030 ptg000009l:5547751-5548971 O23657 1.03e-28 Ras-related protein RABC1 (AtRABC1) (Ras-related protein Rab18) (AtRab18) Arabidopsis thaliana (Mouse-ear cress) intracellular protein transport [GO:0006886] GO:0003924; GO:0005525; GO:0005634; GO:0005794; GO:0005886; GO:0006886; GO:0012505 32613 FUN_038740 1486 1165 1308 3459 1371 NA NA NA NA NA NA NA 32614 FUN_038741 7 3 4 0 0 NA NA NA NA NA NA NA 32615 FUN_038742 3603 3331 2582 2823 2215 NA NA NA NA NA NA NA 32616 FUN_038743 70 81 43 111 205 NA NA NA NA NA NA NA 32617 FUN_028972 68 99 112 193 83 NA NA NA NA NA NA NA 32618 FUN_009554 216 0 0 16 25 ptg000004l:8460087-8470803 Q96AY4 3.27e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32619 FUN_009554 216 0 0 16 25 ptg000004l:8460087-8470803 Q96AY4 2.72e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32620 FUN_009554 216 0 0 16 25 ptg000004l:8460087-8470803 Q96AY4 1.88e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32621 FUN_015031 657 770 526 537 609 NA NA NA NA NA NA NA 32622 FUN_028971 2323 1190 608 1388 1430 ptg000022l:6565600-6587412 Q4G017 2.24e-23 Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline-1 receptor) (I1R) Rattus norvegicus (Rat) actin cytoskeleton organization [GO:0030036]; apoptotic process [GO:0006915]; glucose metabolic process [GO:0006006]; negative regulation of cell migration [GO:0030336]; norepinephrine secretion [GO:0048243]; Rac protein signal transduction [GO:0016601]; regulation of blood pressure [GO:0008217]; regulation of synaptic transmission, GABAergic [GO:0032228] GO:0005178; GO:0005737; GO:0005769; GO:0005829; GO:0005886; GO:0006006; GO:0006915; GO:0008217; GO:0016601; GO:0019901; GO:0030036; GO:0030336; GO:0032228; GO:0035091; GO:0042802; GO:0048243; GO:0055037 32623 FUN_038748 44 10 0 32 35 NA NA NA NA NA NA NA 32624 FUN_015036 2474 1405 992 2064 1484 ptg000009l:5528582-5542868 O00562 3.48e-41 Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) Homo sapiens (Human) brain development [GO:0007420]; lipid metabolic process [GO:0006629]; phosphatidylinositol biosynthetic process [GO:0006661]; phospholipid transport [GO:0015914]; phototransduction [GO:0007602]; protein transport [GO:0015031] GO:0005509; GO:0005737; GO:0005789; GO:0005811; GO:0005829; GO:0006629; GO:0006661; GO:0007420; GO:0007602; GO:0008525; GO:0008526; GO:0015031; GO:0015914; GO:0016020; GO:0030496; GO:0030971; GO:0031210; GO:0032154; GO:0032580; GO:0035091; GO:0043231; GO:0044297; GO:0070300 32625 FUN_028974 521 315 166 318 273 NA NA NA NA NA NA NA 32626 FUN_009557 28 5 1 98 2 NA NA NA NA NA NA NA 32627 FUN_029459 252 47 106 135 313 NA NA NA NA NA NA NA 32628 FUN_024676 1 0 12 0 2 NA NA NA NA NA NA NA 32629 FUN_012795 378 18 170 396 377 ptg000008l:12934200-12963319 Q9P215 3.89e-89 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 32630 FUN_020616 0 0 0 6 25 NA NA NA NA NA NA NA 32631 FUN_020615 0 0 0 41 6 NA NA NA NA NA NA NA 32632 FUN_020614 0 0 0 26 254 NA NA NA NA NA NA NA 32633 FUN_020613 0 0 0 0 14 NA NA NA NA NA NA NA 32634 FUN_020612 0 0 0 0 39 NA NA NA NA NA NA NA 32635 FUN_020610 0 0 0 0 10 NA NA NA NA NA NA NA 32636 FUN_029450 0 1 0 15 3 NA NA NA NA NA NA NA 32637 FUN_029451 2595 2095 1356 2032 1408 NA NA NA NA NA NA NA 32638 FUN_016629 0 7 0 57 0 NA NA NA NA NA NA NA 32639 FUN_016625 9 0 0 21 26 NA NA NA NA NA NA NA 32640 FUN_022923 35 43 0 44 210 NA NA NA NA NA NA NA 32641 FUN_022922 2467 745 1262 2647 994 NA NA NA NA NA NA NA 32642 FUN_022921 3977 3253 1910 8115 3786 NA NA NA NA NA NA NA 32643 FUN_022920 0 0 2 25 0 NA NA NA NA NA NA NA 32644 FUN_022927 212 26 44 125 28 ptg000017l:1639371-1640938 F1RBC8 9.35e-88 ATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP) Danio rerio (Zebrafish) (Brachydanio rerio) adrenal gland development [GO:0030325]; cholesterol transport [GO:0030301]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import into peroxisome [GO:0015910]; motor behavior [GO:0061744]; oligodendrocyte development [GO:0014003]; peroxisome organization [GO:0007031]; positive regulation of myelination [GO:0031643]; swimming behavior [GO:0036269]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0005324; GO:0005524; GO:0005777; GO:0005778; GO:0006635; GO:0007031; GO:0014003; GO:0015607; GO:0015910; GO:0016887; GO:0030301; GO:0030325; GO:0031643; GO:0036269; GO:0042626; GO:0042760; GO:0047617; GO:0061744 32645 FUN_022926 153 24 6 94 19 ptg000017l:1633881-1634995 F1RBC8 3.72e-52 ATP-binding cassette sub-family D member 1 (EC 3.1.2.-) (EC 7.6.2.-) (Adrenoleukodystrophy protein) (ALDP) Danio rerio (Zebrafish) (Brachydanio rerio) adrenal gland development [GO:0030325]; cholesterol transport [GO:0030301]; fatty acid beta-oxidation [GO:0006635]; long-chain fatty acid import into peroxisome [GO:0015910]; motor behavior [GO:0061744]; oligodendrocyte development [GO:0014003]; peroxisome organization [GO:0007031]; positive regulation of myelination [GO:0031643]; swimming behavior [GO:0036269]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0005324; GO:0005524; GO:0005777; GO:0005778; GO:0006635; GO:0007031; GO:0014003; GO:0015607; GO:0015910; GO:0016887; GO:0030301; GO:0030325; GO:0031643; GO:0036269; GO:0042626; GO:0042760; GO:0047617; GO:0061744 32646 FUN_022925 9144 7973 3497 11729 4743 NA NA NA NA NA NA NA 32647 FUN_022924 4 6 9 41 8 NA NA NA NA NA NA NA 32648 FUN_042903 1021 660 516 1736 1961 ptg000047l:1518013-1588126 Q63HN8 3.95e-39 E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213) Homo sapiens (Human) angiogenesis [GO:0001525]; defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein ubiquitination [GO:0016567]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0001525; GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005737; GO:0005811; GO:0005829; GO:0006511; GO:0016020; GO:0016567; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0051865; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 32649 FUN_022928 1440 725 759 1045 1059 ptg000017l:1648128-1664241 Q80Y98 2.33e-23 Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (SAM, WWE and DDHD domain-containing protein 1) Mus musculus (Mouse) lipid droplet organization [GO:0034389]; locomotory behavior [GO:0007626]; mitochondrial fission [GO:0000266]; positive regulation of mitochondrial fission [GO:0090141]; triglyceride catabolic process [GO:0019433]; visual learning [GO:0008542] GO:0000266; GO:0004620; GO:0004806; GO:0005737; GO:0005793; GO:0005794; GO:0005829; GO:0007626; GO:0008542; GO:0016020; GO:0019433; GO:0030134; GO:0034389; GO:0034451; GO:0046872; GO:0090141 32650 FUN_016622 4759 5135 2397 4391 2853 NA NA NA NA NA NA NA 32651 FUN_027344 73 0 46 0 151 NA NA NA NA NA NA NA 32652 FUN_027346 0 0 5 0 29 NA NA NA NA NA NA NA 32653 FUN_027347 4 0 0 0 118 NA NA NA NA NA NA NA 32654 FUN_027340 0 0 27 0 0 NA NA NA NA NA NA NA 32655 FUN_042901 3578 50 183 4744 3275 NA NA NA NA NA NA NA 32656 FUN_027342 0 0 0 0 7 NA NA NA NA NA NA NA 32657 FUN_027343 14 0 6 0 26 NA NA NA NA NA NA NA 32658 FUN_042900 923 0 66 1408 1101 ptg000047l:1470870-1484607 A0A0R4I9Y1 2.33e-34 E3 ubiquitin-protein ligase rnf213-beta (EC 2.3.2.27) (EC 3.6.4.-) (E3 ubiquitin-lipopolysaccharide ligase rnf213-beta) (EC 2.3.2.-) (Mysterin-B) (Mysterin-beta) (RING finger protein 213-B) (RING finger protein 213-beta) Danio rerio (Zebrafish) (Brachydanio rerio) defense response to bacterium [GO:0042742]; immune system process [GO:0002376]; lipid droplet formation [GO:0140042]; lipid ubiquitination [GO:0120323]; negative regulation of non-canonical Wnt signaling pathway [GO:2000051]; protein K63-linked ubiquitination [GO:0070534]; regulation of lipid metabolic process [GO:0019216]; sprouting angiogenesis [GO:0002040]; ubiquitin-dependent protein catabolic process [GO:0006511]; xenophagy [GO:0098792] GO:0002040; GO:0002376; GO:0004842; GO:0005524; GO:0005730; GO:0005811; GO:0005829; GO:0006511; GO:0016887; GO:0019216; GO:0042742; GO:0046872; GO:0061630; GO:0070534; GO:0098792; GO:0120323; GO:0140042; GO:2000051 32659 FUN_027348 75 0 3 49 0 NA NA NA NA NA NA NA 32660 FUN_027349 4 5 0 7 8 NA NA NA NA NA NA NA 32661 FUN_017978 134 33 18 25 28 ptg000012l:2629749-2681082 Q95SX7 3.38e-29 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32662 FUN_017978 134 33 18 25 28 ptg000012l:2629749-2681082 Q95SX7 1.35e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32663 FUN_017978 134 33 18 25 28 ptg000012l:2629749-2681082 Q95SX7 1.35e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32664 FUN_041464 149 128 201 245 410 NA NA NA NA NA NA NA 32665 FUN_004000 883 380 859 1635 1197 NA NA NA NA NA NA NA 32666 FUN_004001 65 134 45 180 83 ntLink_8:17923962-17928036 P83852 7.6e-77 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 32667 FUN_004001 65 134 45 180 83 ntLink_8:17923962-17928036 P83852 2.26e-39 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 32668 FUN_004002 189 209 44 103 102 ntLink_8:17928984-17930846 P83852 1.49e-123 Carboxypeptidase D (EC 3.4.17.22) (CPD-2) (Metallocarboxypeptidase D) Lophonetta specularioides (Crested duck) (Anas specularioides) proteolysis [GO:0006508] GO:0004181; GO:0006508; GO:0008270; GO:0016020 32669 FUN_004003 9962 20846 7356 14415 4408 ntLink_8:17935453-17936570 O35738 1.23e-45 Krueppel-like factor 12 (Transcriptional repressor AP-2rep) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription [GO:0006355]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0001227; GO:0003677; GO:0003700; GO:0005654; GO:0005829; GO:0006355; GO:0006357; GO:0045944; GO:0046872; GO:1990837 32670 FUN_004004 43 21 20 28 15 NA NA NA NA NA NA NA 32671 FUN_004005 1810 2812 1185 3074 2514 NA NA NA NA NA NA NA 32672 FUN_004006 11139 10701 3827 7190 3826 NA NA NA NA NA NA NA 32673 FUN_004007 2150 1932 1111 1746 1381 NA NA NA NA NA NA NA 32674 FUN_004008 2299 1962 939 1663 1301 NA NA NA NA NA NA NA 32675 FUN_004009 13 17 12 6 28 NA NA NA NA NA NA NA 32676 FUN_027838 239 119 129 650 544 NA NA NA NA NA NA NA 32677 FUN_027839 38 22 57 66 91 NA NA NA NA NA NA NA 32678 FUN_018018 1186 870 674 959 1131 ptg000012l:3397619-3417281 A7Z061 6.99e-28 Cell division cycle protein 27 homolog Bos taurus (Bovine) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell division [GO:0051301]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]; protein K11-linked ubiquitination [GO:0070979]; protein ubiquitination [GO:0016567] GO:0005634; GO:0005680; GO:0005737; GO:0005819; GO:0007091; GO:0016567; GO:0031145; GO:0045842; GO:0051301; GO:0070979 32679 FUN_018019 3947 5371 1417 3369 1504 ptg000012l:3426255-3431284 Q9I3S3 3.44e-23 Guanidinobutyrase (EC 3.5.3.7) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) arginine catabolic process [GO:0006527]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389] GO:0006527; GO:0008783; GO:0033389; GO:0046872; GO:0047971 32680 FUN_018019 3947 5371 1417 3369 1504 ptg000012l:3426255-3431284 Q9I3S3 1.86e-22 Guanidinobutyrase (EC 3.5.3.7) Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) arginine catabolic process [GO:0006527]; putrescine biosynthetic process from arginine, using agmatinase [GO:0033389] GO:0006527; GO:0008783; GO:0033389; GO:0046872; GO:0047971 32681 FUN_018016 286 206 107 19 73 NA NA NA NA NA NA NA 32682 FUN_018017 8626 6382 2910 5373 3490 ptg000012l:3385363-3392312 Q5ZHW4 3.55e-51 Ras-related protein Rab-5B (EC 3.6.5.2) Gallus gallus (Chicken) endocytosis [GO:0006897]; intracellular protein transport [GO:0006886]; regulation of endocytosis [GO:0030100] GO:0003924; GO:0003925; GO:0005525; GO:0005768; GO:0005769; GO:0005886; GO:0006886; GO:0006897; GO:0012505; GO:0019003; GO:0030100; GO:0030139; GO:0031901 32683 FUN_018014 1424 898 454 788 566 NA NA NA NA NA NA NA 32684 FUN_018015 339 165 192 222 1147 NA NA NA NA NA NA NA 32685 FUN_017976 0 13 2 0 0 NA NA NA NA NA NA NA 32686 FUN_027835 2200 1108 840 996 572 NA NA NA NA NA NA NA 32687 FUN_018709 80 11 69 40 14 NA NA NA NA NA NA NA 32688 FUN_023339 2108 1818 1214 1479 936 NA NA NA NA NA NA NA 32689 FUN_023338 1886 1735 1601 1874 1124 ptg000017l:6458893-6459832 Q920A6 3.05e-81 Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1) Rattus norvegicus (Rat) blood vessel diameter maintenance [GO:0097746]; negative regulation of blood pressure [GO:0045776]; proteolysis [GO:0006508]; retinoic acid metabolic process [GO:0042573] GO:0004185; GO:0005576; GO:0005829; GO:0006508; GO:0042573; GO:0045776; GO:0097746 32690 FUN_026129 1 14 26 26 0 NA NA NA NA NA NA NA 32691 FUN_023331 0 18 0 0 0 ptg000017l:6422773-6424746 Q91770 2.19e-22 Homeobox protein not2 (Xnot-2) (Xnot2) Xenopus laevis (African clawed frog) negative regulation of DNA-templated transcription [GO:0045892]; notochord formation [GO:0014028] GO:0000981; GO:0003677; GO:0005634; GO:0014028; GO:0045892 32692 FUN_023330 1148 367 282 1798 1030 NA NA NA NA NA NA NA 32693 FUN_023333 770 400 471 545 723 NA NA NA NA NA NA NA 32694 FUN_023334 3579 3371 3260 4328 2307 ptg000017l:6442220-6446983 Q9HB40 4.81e-93 Retinoid-inducible serine carboxypeptidase (EC 3.4.16.-) (Serine carboxypeptidase 1) Homo sapiens (Human) blood vessel diameter maintenance [GO:0097746]; negative regulation of blood pressure [GO:0045776]; proteolysis [GO:0006508]; retinoic acid metabolic process [GO:0042573] GO:0004185; GO:0005829; GO:0006508; GO:0042573; GO:0045776; GO:0070062; GO:0097746 32695 FUN_023337 0 4 3 6 14 NA NA NA NA NA NA NA 32696 FUN_026120 5 109 58 30 0 NA NA NA NA NA NA NA 32697 FUN_025478 0 0 0 0 7 NA NA NA NA NA NA NA 32698 FUN_025479 0 35 0 0 12 NA NA NA NA NA NA NA 32699 FUN_025474 14 0 0 0 52 NA NA NA NA NA NA NA 32700 FUN_025476 49 203 352 14 898 ptg000019l:3243063-3263777 P35556 4.69e-22 Fibrillin-2 [Cleaved into: Placensin] Homo sapiens (Human) anatomical structure morphogenesis [GO:0009653]; bone trabecula formation [GO:0060346]; camera-type eye development [GO:0043010]; embryonic eye morphogenesis [GO:0048048]; embryonic limb morphogenesis [GO:0030326]; glucose homeostasis [GO:0042593]; placenta development [GO:0001890]; positive regulation of bone mineralization [GO:0030501]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of trophoblast cell migration [GO:1901163]; sequestering of TGFbeta in extracellular matrix [GO:0035583] GO:0001527; GO:0001890; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0009653; GO:0030023; GO:0030326; GO:0030501; GO:0031012; GO:0035583; GO:0042593; GO:0043010; GO:0045669; GO:0048048; GO:0060346; GO:0062023; GO:1901163 32701 FUN_025477 0 1 12 0 15 NA NA NA NA NA NA NA 32702 FUN_025473 0 0 5 0 30 NA NA NA NA NA NA NA 32703 FUN_035102 0 0 0 0 10 NA NA NA NA NA NA NA 32704 FUN_039868 725 250 335 897 762 NA NA NA NA NA NA NA 32705 FUN_039869 133 230 55 102 49 NA NA NA NA NA NA NA 32706 FUN_033808 87 13 18 87 72 NA NA NA NA NA NA NA 32707 FUN_033809 418 532 239 365 342 NA NA NA NA NA NA NA 32708 FUN_039862 190 248 100 108 288 ptg000031l:1042051-1045929 Q5RAY7 2.21e-41 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (EC 2.1.1.296) (Cap methyltransferase 2) (Cap2 2'O-ribose methyltransferase 2) (MTr2) (FtsJ methyltransferase domain-containing protein 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 7-methylguanosine mRNA capping [GO:0006370]; cap2 mRNA methylation [GO:0097310] GO:0004483; GO:0005634; GO:0005737; GO:0006370; GO:0097310 32709 FUN_033807 900 1336 398 613 313 ptg000024l:1590322-1593042 Q9VGY5 5.08e-35 Probable methyltransferase-like protein 15 homolog (EC 2.1.1.-) Drosophila melanogaster (Fruit fly) rRNA base methylation [GO:0070475] GO:0070475; GO:0071424 32710 FUN_039860 2256 1303 1472 2331 2115 NA NA NA NA NA NA NA 32711 FUN_039861 60 15 33 22 33 ptg000031l:1037051-1039636 D2H8V8 2.36e-106 5' exonuclease Apollo (EC 3.1.-.-) (Beta-lactamase MBLAC2) (EC 3.5.2.6) (DNA cross-link repair 1B protein) (SNM1 homolog B) Ailuropoda melanoleuca (Giant panda) DNA repair [GO:0006281]; protection from non-homologous end joining at telomere [GO:0031848]; telomere maintenance [GO:0000723]; telomeric 3' overhang formation [GO:0031860]; telomeric loop formation [GO:0031627] GO:0000723; GO:0000781; GO:0005634; GO:0005737; GO:0005813; GO:0006281; GO:0008409; GO:0008800; GO:0031627; GO:0031848; GO:0031860 32712 FUN_033802 279 141 42 273 235 NA NA NA NA NA NA NA 32713 FUN_033803 363 252 68 296 639 NA NA NA NA NA NA NA 32714 FUN_033800 3094 1586 951 1492 518 NA NA NA NA NA NA NA 32715 FUN_033801 90 139 68 28 28 NA NA NA NA NA NA NA 32716 FUN_018908 0 0 13 64 25 NA NA NA NA NA NA NA 32717 FUN_018909 5 0 21 258 347 NA NA NA NA NA NA NA 32718 FUN_018904 0 0 0 0 12 NA NA NA NA NA NA NA 32719 FUN_018905 37 45 690 1593 68 NA NA NA NA NA NA NA 32720 FUN_018907 0 0 0 41 0 NA NA NA NA NA NA NA 32721 FUN_018903 19 0 0 54 68 NA NA NA NA NA NA NA 32722 FUN_002809 4350 2766 1454 3483 1580 NA NA NA NA NA NA NA 32723 FUN_005836 0 5 14 0 80 NA NA NA NA NA NA NA 32724 FUN_005837 0 0 0 0 7 NA NA NA NA NA NA NA 32725 FUN_005834 43 0 19 30 0 NA NA NA NA NA NA NA 32726 FUN_005832 99 34 94 53 158 ptg000001l:4547802-4554833 Q1KYK5 2.46e-44 Protein Wnt-7a Pongo pygmaeus (Bornean orangutan) cell differentiation [GO:0030154]; system development [GO:0048731]; tissue development [GO:0009888]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009888; GO:0016055; GO:0030154; GO:0048731 32727 FUN_005832 99 34 94 53 158 ptg000001l:4547802-4554833 Q1KYK5 1.68e-31 Protein Wnt-7a Pongo pygmaeus (Bornean orangutan) cell differentiation [GO:0030154]; system development [GO:0048731]; tissue development [GO:0009888]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009888; GO:0016055; GO:0030154; GO:0048731 32728 FUN_005833 199 826 223 294 119 NA NA NA NA NA NA NA 32729 FUN_005830 13 12 0 10 0 NA NA NA NA NA NA NA 32730 FUN_005831 0 18 0 0 44 NA NA NA NA NA NA NA 32731 FUN_009850 48 0 64 29 102 ptg000004l:12552800-12558850 P14381 1.89e-119 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 32732 FUN_002803 105 0 13 74 88 NA NA NA NA NA NA NA 32733 FUN_009853 1458 448 342 2894 11 NA NA NA NA NA NA NA 32734 FUN_002806 538 184 312 257 389 ntLink_8:6391075-6403366 Q8NEP9 2.28e-21 Zinc finger protein 555 Homo sapiens (Human) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0005634; GO:0006357; GO:0046872 32735 FUN_009856 5553 5897 4006 4129 1344 NA NA NA NA NA NA NA 32736 FUN_036079 2822 1052 849 1359 836 NA NA NA NA NA NA NA 32737 FUN_009857 87209 79197 48299 105859 87814 ptg000004l:12636410-12642203 Q9YIC0 3.21e-51 Elongation factor 1-alpha (EF-1-alpha) Oryzias latipes (Japanese rice fish) (Japanese killifish) translation [GO:0006412]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006412; GO:0006414 32738 FUN_009857 87209 79197 48299 105859 87814 ptg000004l:12636410-12642203 Q9YIC0 5.92e-40 Elongation factor 1-alpha (EF-1-alpha) Oryzias latipes (Japanese rice fish) (Japanese killifish) translation [GO:0006412]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006412; GO:0006414 32739 FUN_009857 87209 79197 48299 105859 87814 ptg000004l:12636410-12642203 Q9YIC0 9.6e-38 Elongation factor 1-alpha (EF-1-alpha) Oryzias latipes (Japanese rice fish) (Japanese killifish) translation [GO:0006412]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006412; GO:0006414 32740 FUN_009857 87209 79197 48299 105859 87814 ptg000004l:12636410-12642203 Q9YIC0 1.36e-27 Elongation factor 1-alpha (EF-1-alpha) Oryzias latipes (Japanese rice fish) (Japanese killifish) translation [GO:0006412]; translational elongation [GO:0006414] GO:0003746; GO:0003924; GO:0005525; GO:0005737; GO:0006412; GO:0006414 32741 FUN_030385 6 0 8 0 30 ptg000023l:10746290-10747053 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32742 FUN_030387 9 0 7 0 29 ptg000023l:10750342-10751105 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32743 FUN_030381 5 0 7 0 24 ptg000023l:10738186-10738949 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32744 FUN_030383 4 0 11 0 21 ptg000023l:10742238-10743001 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32745 FUN_030389 6 0 12 0 28 ptg000023l:10754394-10755157 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32746 FUN_006339 717 181 435 628 529 NA NA NA NA NA NA NA 32747 FUN_043157 2156 2299 1532 2171 2212 NA NA NA NA NA NA NA 32748 FUN_006330 2659 1884 1315 2244 1452 NA NA NA NA NA NA NA 32749 FUN_006331 2955 1342 1848 3802 2717 NA NA NA NA NA NA NA 32750 FUN_006333 1730 2608 863 1342 731 NA NA NA NA NA NA NA 32751 FUN_006334 0 18 26 19 0 NA NA NA NA NA NA NA 32752 FUN_006335 71 20 50 105 114 NA NA NA NA NA NA NA 32753 FUN_006336 2716 2814 1717 1838 1193 ptg000001l:11039787-11045682 Q9UIV1 1.34e-26 CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a) Homo sapiens (Human) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; defense response to virus [GO:0051607]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; miRNA-mediated gene silencing [GO:0035195]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; P-body assembly [GO:0033962]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral genome replication [GO:0045070]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; RNA-mediated gene silencing [GO:0031047] GO:0000175; GO:0000289; GO:0000290; GO:0000932; GO:0003714; GO:0003723; GO:0004532; GO:0004535; GO:0005634; GO:0005737; GO:0005829; GO:0008284; GO:0008285; GO:0010629; GO:0016020; GO:0016604; GO:0016607; GO:0030014; GO:0030015; GO:0031047; GO:0033962; GO:0035195; GO:0042509; GO:0043928; GO:0045070; GO:0045892; GO:0045944; GO:0046872; GO:0051607; GO:0060213; GO:0060339; GO:0061014; GO:0140297; GO:1900153 32754 FUN_006336 2716 2814 1717 1838 1193 ptg000001l:11039787-11045682 Q9UIV1 2.02e-21 CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a) Homo sapiens (Human) deadenylation-dependent decapping of nuclear-transcribed mRNA [GO:0000290]; defense response to virus [GO:0051607]; exonucleolytic catabolism of deadenylated mRNA [GO:0043928]; miRNA-mediated gene silencing [GO:0035195]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; negative regulation of type I interferon-mediated signaling pathway [GO:0060339]; nuclear-transcribed mRNA poly(A) tail shortening [GO:0000289]; P-body assembly [GO:0033962]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of mRNA catabolic process [GO:0061014]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of viral genome replication [GO:0045070]; regulation of tyrosine phosphorylation of STAT protein [GO:0042509]; RNA-mediated gene silencing [GO:0031047] GO:0000175; GO:0000289; GO:0000290; GO:0000932; GO:0003714; GO:0003723; GO:0004532; GO:0004535; GO:0005634; GO:0005737; GO:0005829; GO:0008284; GO:0008285; GO:0010629; GO:0016020; GO:0016604; GO:0016607; GO:0030014; GO:0030015; GO:0031047; GO:0033962; GO:0035195; GO:0042509; GO:0043928; GO:0045070; GO:0045892; GO:0045944; GO:0046872; GO:0051607; GO:0060213; GO:0060339; GO:0061014; GO:0140297; GO:1900153 32755 FUN_036973 42 23 58 84 42 NA NA NA NA NA NA NA 32756 FUN_036972 18 0 28 0 72 NA NA NA NA NA NA NA 32757 FUN_036975 122 39 47 69 166 NA NA NA NA NA NA NA 32758 FUN_036974 56 0 0 0 65 NA NA NA NA NA NA NA 32759 FUN_036977 2070 1576 653 910 1645 NA NA NA NA NA NA NA 32760 FUN_036976 185 86 25 57 79 NA NA NA NA NA NA NA 32761 FUN_036979 1176 453 651 1027 1189 NA NA NA NA NA NA NA 32762 FUN_036978 37 61 33 69 161 NA NA NA NA NA NA NA 32763 FUN_035776 534 355 233 411 318 NA NA NA NA NA NA NA 32764 FUN_035777 1491 1107 1060 1429 1048 NA NA NA NA NA NA NA 32765 FUN_035774 1185 2131 512 1774 904 NA NA NA NA NA NA NA 32766 FUN_035775 2245 1313 1341 1981 1693 NA NA NA NA NA NA NA 32767 FUN_035772 361 390 138 354 138 NA NA NA NA NA NA NA 32768 FUN_035773 377 179 142 142 256 NA NA NA NA NA NA NA 32769 FUN_035770 1329 724 550 600 600 ptg000025l:11513403-11517742 A2VDS1 5.16e-42 Selenocysteine lyase (EC 4.4.1.16) Bos taurus (Bovine) NA GO:0005794; GO:0005829; GO:0009000; GO:0016740 32770 FUN_035770 1329 724 550 600 600 ptg000025l:11513403-11517742 A2VDS1 1.31e-32 Selenocysteine lyase (EC 4.4.1.16) Bos taurus (Bovine) NA GO:0005794; GO:0005829; GO:0009000; GO:0016740 32771 FUN_035771 2960 1681 855 696 1774 ptg000025l:11518008-11528773 Q17QR8 2.34e-29 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Bos taurus (Bovine) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 32772 FUN_035778 112 52 135 58 74 ptg000025l:11605490-11606453 Q8BTH6 4.1e-77 Transcriptional repressor scratch 2 (Scratch homolog 2 zinc finger protein) Mus musculus (Mouse) negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron migration [GO:2001222] GO:0000122; GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872; GO:1990837; GO:2001222 32773 FUN_035779 1698 849 783 751 922 NA NA NA NA NA NA NA 32774 FUN_003867 17 0 9 17 14 ntLink_8:16311374-16312992 A0A0C2SRU0 2.48e-75 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32775 FUN_003863 95 18 326 341 199 ntLink_8:16282603-16284063 A0A0C2SRU0 3.23e-83 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32776 FUN_003862 731 123 442 541 202 NA NA NA NA NA NA NA 32777 FUN_003861 78 26 463 53 83 ntLink_8:16259796-16266613 A0A0C2SRU0 2.79e-72 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32778 FUN_003860 23 0 35 0 87 NA NA NA NA NA NA NA 32779 FUN_003869 370 47 596 648 531 ntLink_8:16335331-16336693 A0A0C2SRU0 1.67e-80 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32780 FUN_003868 74 19 171 123 145 ntLink_8:16325857-16331391 A0A0C2SRU0 5.79e-77 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 32781 FUN_031475 2 2 3 30 4 NA NA NA NA NA NA NA 32782 FUN_031477 72 100 22 0 34 ptg000023l:21890612-21894328 Q5FYA8 3.51e-37 Arylsulfatase H (ASH) (EC 3.1.6.-) Homo sapiens (Human) NA GO:0004065; GO:0005788; GO:0016020; GO:0046872 32783 FUN_031476 90 278 85 433 270 NA NA NA NA NA NA NA 32784 FUN_031473 0 0 1 0 17 NA NA NA NA NA NA NA 32785 FUN_031472 457 281 153 601 547 ptg000023l:21848819-21856418 Q6DCX5 1.64e-24 Proton-coupled folate transporter (Heme carrier protein 1) (Solute carrier family 46 member 1) Xenopus laevis (African clawed frog) NA GO:0005542; GO:0005768; GO:0010008; GO:0015293; GO:0015350; GO:0016323; GO:0016324 32786 FUN_031479 0 0 8 0 0 NA NA NA NA NA NA NA 32787 FUN_035534 6854 6581 4243 6341 7577 NA NA NA NA NA NA NA 32788 FUN_035537 4170 3002 1653 2830 1970 ptg000025l:8709940-8736143 Q5RBI5 2.44e-37 Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (Spliceosome-associated protein 130) (SAP 130) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003676; GO:0005634; GO:0071005 32789 FUN_035537 4170 3002 1653 2830 1970 ptg000025l:8709940-8736143 Q5RBI5 2.32e-30 Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (Spliceosome-associated protein 130) (SAP 130) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003676; GO:0005634; GO:0071005 32790 FUN_035537 4170 3002 1653 2830 1970 ptg000025l:8709940-8736143 Q5RBI5 8.16e-25 Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (Spliceosome-associated protein 130) (SAP 130) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003676; GO:0005634; GO:0071005 32791 FUN_035537 4170 3002 1653 2830 1970 ptg000025l:8709940-8736143 Q5RBI5 6.4e-24 Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (Spliceosome-associated protein 130) (SAP 130) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003676; GO:0005634; GO:0071005 32792 FUN_001649 803 669 689 1022 360 ntLink_6:14594662-14599170 P19971 1.08e-34 Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase) Homo sapiens (Human) angiogenesis [GO:0001525]; cell differentiation [GO:0030154]; chemotaxis [GO:0006935]; dTMP catabolic process [GO:0046074]; mitochondrial genome maintenance [GO:0000002]; pyrimidine nucleobase metabolic process [GO:0006206]; pyrimidine nucleoside metabolic process [GO:0006213]; regulation of gastric motility [GO:1905333]; regulation of myelination [GO:0031641]; regulation of transmission of nerve impulse [GO:0051969] GO:0000002; GO:0001525; GO:0004645; GO:0005829; GO:0006206; GO:0006213; GO:0006935; GO:0008083; GO:0009032; GO:0016154; GO:0030154; GO:0031641; GO:0042803; GO:0046074; GO:0051969; GO:1905333 32793 FUN_001648 18709 20350 8847 17640 9300 NA NA NA NA NA NA NA 32794 FUN_035532 0 0 0 0 42 NA NA NA NA NA NA NA 32795 FUN_001640 183 161 45 121 89 ntLink_6:14546771-14547887 Q9Y5X5 8.23e-27 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 32796 FUN_001645 0 15 0 11 0 NA NA NA NA NA NA NA 32797 FUN_001646 171 111 10 168 208 NA NA NA NA NA NA NA 32798 FUN_032235 2313 2946 2580 5129 4273 NA NA NA NA NA NA NA 32799 FUN_029979 16 105 24 21 36 NA NA NA NA NA NA NA 32800 FUN_032233 5132 3186 2221 5351 3042 NA NA NA NA NA NA NA 32801 FUN_005869 8 20 0 4 0 NA NA NA NA NA NA NA 32802 FUN_037739 3453 2259 1931 2580 1885 ptg000026l:12992109-12996321 Q01460 1.15e-34 Di-N-acetylchitobiase (EC 3.2.1.-) Rattus norvegicus (Rat) chitin catabolic process [GO:0006032]; oligosaccharide catabolic process [GO:0009313] GO:0004568; GO:0005764; GO:0006032; GO:0008061; GO:0009313; GO:0016798 32803 FUN_037730 0 0 13 13 0 ptg000026l:12861987-12865922 P97846 6.85e-32 Contactin-associated protein 1 (Caspr) (Caspr1) (Neurexin IV) (Neurexin-4) (Paranodin) (p190) Rattus norvegicus (Rat) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 32804 FUN_037731 0 18 0 32 0 ptg000026l:12872802-12876086 Q9UHC6 1.06e-34 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 32805 FUN_037732 60 20 47 68 18 ptg000026l:12880625-12884505 Q9UHC6 3.61e-33 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 32806 FUN_037735 76 0 75 42 75 ptg000026l:12930126-12949998 Q9UHC6 2.06e-30 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 32807 FUN_037735 76 0 75 42 75 ptg000026l:12930126-12949998 Q9UHC6 2.77e-30 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 32808 FUN_037735 76 0 75 42 75 ptg000026l:12930126-12949998 Q9UHC6 3.33e-26 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 32809 FUN_037736 26 27 0 7 38 ptg000026l:12957221-12962598 Q9UHC6 3.33e-31 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 32810 FUN_005018 8129 4604 4923 7268 6756 NA NA NA NA NA NA NA 32811 FUN_005019 1313 898 740 976 1017 NA NA NA NA NA NA NA 32812 FUN_000068 0 0 2 0 8 ntLink_4:49134-50329 P35061 7.49e-82 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32813 FUN_000069 3 0 4 0 13 ntLink_4:51816-54384 P84239 4.97e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32814 FUN_005010 82 33 18 14 21 NA NA NA NA NA NA NA 32815 FUN_005011 19 12 0 8 0 NA NA NA NA NA NA NA 32816 FUN_005013 54 18 6 5 13 NA NA NA NA NA NA NA 32817 FUN_000061 8 0 12 0 21 ntLink_4:31492-32255 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 32818 FUN_016101 2263 1476 1217 1489 1662 NA NA NA NA NA NA NA 32819 FUN_032816 1 1 8 2 0 NA NA NA NA NA NA NA 32820 FUN_032817 2271 1875 1626 2278 2618 NA NA NA NA NA NA NA 32821 FUN_032814 980 554 705 1004 1237 NA NA NA NA NA NA NA 32822 FUN_032815 43212 33219 21762 21701 18863 ptg000023l:36295204-36298862 Q9C0D7 8.38e-74 Probable ribonuclease ZC3H12C (EC 3.1.-.-) (MCP-induced protein 3) (Zinc finger CCCH domain-containing protein 12C) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502] GO:0003729; GO:0004521; GO:0005634; GO:0036464; GO:0046872; GO:0090502 32823 FUN_032812 0 17 13 2 0 NA NA NA NA NA NA NA 32824 FUN_032813 288 524 441 339 466 NA NA NA NA NA NA NA 32825 FUN_032810 173 99 133 254 183 ptg000023l:36170489-36216571 P21328 7.25e-22 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 32826 FUN_032810 173 99 133 254 183 ptg000023l:36170489-36216571 P21328 7.25e-22 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 32827 FUN_032811 106 72 138 164 112 NA NA NA NA NA NA NA 32828 FUN_016106 1205 417 638 1045 789 ptg000010l:1633589-1649477 P0CT39 1.19e-44 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 32829 FUN_032819 0 0 0 0 16 NA NA NA NA NA NA NA 32830 FUN_042268 58 49 55 34 92 NA NA NA NA NA NA NA 32831 FUN_015041 5423 5661 2428 4544 2357 NA NA NA NA NA NA NA 32832 FUN_008279 4150 2566 1233 3830 1762 ptg000002l:9897927-9899040 Q9ES74 1.26e-21 Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7) Mus musculus (Mouse) cellular response to potassium ion [GO:0035865]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of NLRP3 inflammasome complex assembly [GO:1900227]; positive regulation of telomerase activity [GO:0051973]; positive regulation of telomere capping [GO:1904355]; positive regulation of telomere maintenance via telomerase [GO:0032212]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0004674; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005815; GO:0006468; GO:0007346; GO:0018105; GO:0032212; GO:0035865; GO:0046872; GO:0051973; GO:0106310; GO:0140677; GO:1900227; GO:1904355 32833 FUN_008278 987 706 394 1271 883 ptg000002l:9889398-9894532 Q5RBG4 1.19e-44 Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; chromatin organization [GO:0006325]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of mitotic spindle orientation [GO:0000132]; histone acetylation [GO:0016573]; innate immune response [GO:0045087]; lipid droplet disassembly [GO:1905691]; nucleotide-excision repair [GO:0006289]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagy [GO:0010508]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of hematopoietic stem cell differentiation [GO:1902036]; spermatid development [GO:0007286] GO:0000132; GO:0000724; GO:0000776; GO:0000812; GO:0000922; GO:0003682; GO:0003713; GO:0004402; GO:0005634; GO:0005730; GO:0005737; GO:0006289; GO:0006302; GO:0006325; GO:0006974; GO:0006978; GO:0007286; GO:0010508; GO:0010867; GO:0016573; GO:0018394; GO:0032777; GO:0035267; GO:0042149; GO:0042753; GO:0043998; GO:0045087; GO:0045591; GO:0045663; GO:0045893; GO:0045944; GO:0046872; GO:0048471; GO:0061733; GO:0062033; GO:0106226; GO:0140064; GO:0140065; GO:1902036; GO:1902425; GO:1905168; GO:1905691 32834 FUN_008278 987 706 394 1271 883 ptg000002l:9889398-9894532 Q5RBG4 2.28e-29 Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) cellular response to DNA damage stimulus [GO:0006974]; cellular response to glucose starvation [GO:0042149]; chromatin organization [GO:0006325]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; double-strand break repair [GO:0006302]; double-strand break repair via homologous recombination [GO:0000724]; establishment of mitotic spindle orientation [GO:0000132]; histone acetylation [GO:0016573]; innate immune response [GO:0045087]; lipid droplet disassembly [GO:1905691]; nucleotide-excision repair [GO:0006289]; peptidyl-lysine acetylation [GO:0018394]; positive regulation of attachment of mitotic spindle microtubules to kinetochore [GO:1902425]; positive regulation of autophagy [GO:0010508]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of double-strand break repair via homologous recombination [GO:1905168]; positive regulation of mitotic sister chromatid segregation [GO:0062033]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of regulatory T cell differentiation [GO:0045591]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of triglyceride biosynthetic process [GO:0010867]; regulation of hematopoietic stem cell differentiation [GO:1902036]; spermatid development [GO:0007286] GO:0000132; GO:0000724; GO:0000776; GO:0000812; GO:0000922; GO:0003682; GO:0003713; GO:0004402; GO:0005634; GO:0005730; GO:0005737; GO:0006289; GO:0006302; GO:0006325; GO:0006974; GO:0006978; GO:0007286; GO:0010508; GO:0010867; GO:0016573; GO:0018394; GO:0032777; GO:0035267; GO:0042149; GO:0042753; GO:0043998; GO:0045087; GO:0045591; GO:0045663; GO:0045893; GO:0045944; GO:0046872; GO:0048471; GO:0061733; GO:0062033; GO:0106226; GO:0140064; GO:0140065; GO:1902036; GO:1902425; GO:1905168; GO:1905691 32835 FUN_008273 1929 1633 1156 2219 1800 ptg000002l:9851134-9866561 Q9D2H2 1.25e-36 Adenylate kinase 7 (AK 7) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 7) Mus musculus (Mouse) axoneme assembly [GO:0035082]; brain development [GO:0007420]; epithelial cilium movement involved in extracellular fluid movement [GO:0003351]; establishment of localization in cell [GO:0051649]; inflammatory response to antigenic stimulus [GO:0002437]; nucleoside diphosphate phosphorylation [GO:0006165]; nucleoside triphosphate biosynthetic process [GO:0009142]; spermatogenesis [GO:0007283] GO:0002437; GO:0003351; GO:0004017; GO:0004127; GO:0004550; GO:0005524; GO:0005576; GO:0005737; GO:0005829; GO:0006165; GO:0007283; GO:0007420; GO:0009142; GO:0031514; GO:0035082; GO:0051649 32836 FUN_008272 119 104 54 86 62 NA NA NA NA NA NA NA 32837 FUN_008271 15986 13130 4240 8513 8716 ptg000002l:9842332-9845696 Q2HJH2 2.55e-23 Ras-related protein Rab-1B (EC 3.6.5.2) Bos taurus (Bovine) autophagosome assembly [GO:0000045]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0000045; GO:0003924; GO:0003925; GO:0005525; GO:0006886; GO:0007030; GO:0012505; GO:0034045; GO:0048471 32838 FUN_008270 11249 11600 6244 10549 8691 ptg000002l:9836467-9839594 Q2HJH2 3.72e-23 Ras-related protein Rab-1B (EC 3.6.5.2) Bos taurus (Bovine) autophagosome assembly [GO:0000045]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886] GO:0000045; GO:0003924; GO:0003925; GO:0005525; GO:0006886; GO:0007030; GO:0012505; GO:0034045; GO:0048471 32839 FUN_008277 868 796 362 628 553 NA NA NA NA NA NA NA 32840 FUN_008276 1188 1013 477 814 1113 NA NA NA NA NA NA NA 32841 FUN_008275 5742 4820 2286 4934 3768 NA NA NA NA NA NA NA 32842 FUN_008274 1501 1567 1309 1335 1548 ptg000002l:9866704-9869564 Q9VMU8 1.28e-50 UDP-galactose transporter senju Drosophila melanogaster (Fruit fly) carbohydrate transport [GO:0008643]; negative regulation of innate immune response [GO:0045824]; negative regulation of Toll signaling pathway [GO:0045751]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of protein glycosylation [GO:0060050]; UDP-galactose transmembrane transport [GO:0072334] GO:0000139; GO:0002225; GO:0005459; GO:0005794; GO:0005797; GO:0008643; GO:0045751; GO:0045824; GO:0060050; GO:0072334 32843 FUN_004769 0 58 65 184 45 NA NA NA NA NA NA NA 32844 FUN_004768 576 444 147 333 302 NA NA NA NA NA NA NA 32845 FUN_004764 1392 800 505 1902 1110 NA NA NA NA NA NA NA 32846 FUN_004766 10744 4837 2219 13705 16293 NA NA NA NA NA NA NA 32847 FUN_011361 0 0 0 0 25 NA NA NA NA NA NA NA 32848 FUN_040257 0 9 0 0 20 ptg000031l:5973704-5977655 Q62443 6.09e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Mus musculus (Mouse) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005737; GO:0005739; GO:0005886; GO:0006839; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 32849 FUN_040256 0 0 0 9 10 ptg000031l:5960878-5966474 Q15818 1.09e-25 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 32850 FUN_040251 0 0 0 52 48 ptg000031l:5898555-5901892 Q15818 4.45e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 32851 FUN_040250 40 20 6 0 0 ptg000031l:5892986-5896437 Q15818 1.02e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Homo sapiens (Human) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005739; GO:0005886; GO:0006839; GO:0007268; GO:0007417; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 32852 FUN_040253 154 127 30 275 263 NA NA NA NA NA NA NA 32853 FUN_040252 0 9 0 0 30 ptg000031l:5909080-5913031 Q62443 6.09e-26 Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) Mus musculus (Mouse) axonogenesis involved in innervation [GO:0060385]; cellular response to glucose stimulus [GO:0071333]; cellular response to potassium ion [GO:0035865]; mitochondrial fragmentation involved in apoptotic process [GO:0043653]; mitochondrial transport [GO:0006839]; neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0099645]; postsynaptic density assembly [GO:0097107]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962] GO:0005737; GO:0005739; GO:0005886; GO:0006839; GO:0030133; GO:0035865; GO:0043005; GO:0043083; GO:0043653; GO:0046872; GO:0060385; GO:0071333; GO:0097107; GO:0098962; GO:0098978; GO:0099645 32854 FUN_034418 37 96 34 64 14 NA NA NA NA NA NA NA 32855 FUN_034419 3149 2961 1527 3428 2438 NA NA NA NA NA NA NA 32856 FUN_034410 1026 207 365 315 233 ptg000024l:8568456-8609211 Q95SX7 9.79e-34 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32857 FUN_034410 1026 207 365 315 233 ptg000024l:8568456-8609211 Q95SX7 9.79e-34 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32858 FUN_034411 0 11 6 15 12 NA NA NA NA NA NA NA 32859 FUN_034412 42 33 0 0 45 NA NA NA NA NA NA NA 32860 FUN_034413 1 4 0 1 10 NA NA NA NA NA NA NA 32861 FUN_034415 618 522 509 437 539 NA NA NA NA NA NA NA 32862 FUN_034417 6450 4273 3186 7440 7648 NA NA NA NA NA NA NA 32863 FUN_002688 18 8 11 0 7 NA NA NA NA NA NA NA 32864 FUN_002689 159 309 132 176 127 NA NA NA NA NA NA NA 32865 FUN_002684 210 89 351 153 723 NA NA NA NA NA NA NA 32866 FUN_002685 1129 568 429 2723 1786 NA NA NA NA NA NA NA 32867 FUN_002686 0 0 0 0 47 NA NA NA NA NA NA NA 32868 FUN_011193 0 0 0 2 54 NA NA NA NA NA NA NA 32869 FUN_011194 0 0 8 0 22 NA NA NA NA NA NA NA 32870 FUN_011195 0 0 8 0 1 NA NA NA NA NA NA NA 32871 FUN_002682 23575 11702 13357 26852 22463 NA NA NA NA NA NA NA 32872 FUN_002683 4144 2918 3877 9307 6350 ntLink_8:5285480-5345991 Q95SX7 8.18e-25 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32873 FUN_002683 4144 2918 3877 9307 6350 ntLink_8:5285480-5345991 Q95SX7 8.18e-25 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32874 FUN_008084 1618 1576 1267 1247 622 NA NA NA NA NA NA NA 32875 FUN_040879 435 444 370 462 643 NA NA NA NA NA NA NA 32876 FUN_028491 3308 1918 1939 3539 3240 NA NA NA NA NA NA NA 32877 FUN_028490 689 374 408 799 463 NA NA NA NA NA NA NA 32878 FUN_040871 0 0 0 0 25 NA NA NA NA NA NA NA 32879 FUN_040870 383 0 15 3 323 NA NA NA NA NA NA NA 32880 FUN_040875 0 0 19 0 0 NA NA NA NA NA NA NA 32881 FUN_040877 0 16 0 0 0 NA NA NA NA NA NA NA 32882 FUN_040876 0 14 0 0 0 NA NA NA NA NA NA NA 32883 FUN_041035 9 5 0 0 10 NA NA NA NA NA NA NA 32884 FUN_041032 0 16 3 0 0 NA NA NA NA NA NA NA 32885 FUN_002356 2392 1306 939 1138 1928 NA NA NA NA NA NA NA 32886 FUN_002357 418 306 225 505 471 NA NA NA NA NA NA NA 32887 FUN_002354 2357 1230 1001 1840 599 NA NA NA NA NA NA NA 32888 FUN_002355 429 334 230 223 356 NA NA NA NA NA NA NA 32889 FUN_002352 587 263 467 805 603 NA NA NA NA NA NA NA 32890 FUN_002353 848 550 427 645 752 NA NA NA NA NA NA NA 32891 FUN_002350 1228 815 531 766 703 NA NA NA NA NA NA NA 32892 FUN_002351 142 18 58 125 63 ntLink_8:416026-432037 Q95SX7 3.54e-27 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32893 FUN_002351 142 18 58 125 63 ntLink_8:416026-432037 Q95SX7 3.54e-27 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 32894 FUN_002358 24954 28890 12758 22809 15552 NA NA NA NA NA NA NA 32895 FUN_002359 1367 1328 865 1763 666 NA NA NA NA NA NA NA 32896 FUN_012087 43 93 52 196 289 NA NA NA NA NA NA NA 32897 FUN_012086 7 19 0 30 31 ptg000008l:4991353-4991844 Q8BYI9 1.43e-46 Tenascin-R (TN-R) (Janusin) (Neural recognition molecule J1-160/180) (Restrictin) Mus musculus (Mouse) associative learning [GO:0008306]; axon extension [GO:0048675]; axon extension involved in regeneration [GO:0048677]; cell adhesion [GO:0007155]; extracellular matrix organization [GO:0030198]; locomotory exploration behavior [GO:0035641]; long-term synaptic potentiation [GO:0060291]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of axon extension [GO:0030517]; negative regulation of axon extension involved in regeneration [GO:0048692]; negative regulation of cell adhesion [GO:0007162]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of neuron projection development [GO:0010977]; negative regulation of synaptic transmission [GO:0050805]; neuroblast migration [GO:0097402]; neuromuscular process controlling balance [GO:0050885]; neuron cell-cell adhesion [GO:0007158]; positive regulation of synaptic transmission, glutamatergic [GO:0051968]; positive regulation of transmission of nerve impulse [GO:0051971]; regulation of cell adhesion [GO:0030155]; regulation of cell differentiation [GO:0045595]; regulation of cell migration [GO:0030334]; synapse organization [GO:0050808]; synaptic transmission, glutamatergic [GO:0035249]; telencephalon cell migration [GO:0022029] GO:0005102; GO:0005178; GO:0005615; GO:0007155; GO:0007158; GO:0007162; GO:0008306; GO:0009986; GO:0010977; GO:0022029; GO:0022408; GO:0030155; GO:0030198; GO:0030334; GO:0030517; GO:0031012; GO:0035249; GO:0035641; GO:0045121; GO:0045595; GO:0046625; GO:0048675; GO:0048677; GO:0048692; GO:0050804; GO:0050805; GO:0050808; GO:0050885; GO:0051968; GO:0051971; GO:0060291; GO:0062023; GO:0072534; GO:0090733; GO:0097402; GO:0098685; GO:0098686; GO:0098965; GO:0098966; GO:0098978 32898 FUN_012085 45 81 31 28 103 NA NA NA NA NA NA NA 32899 FUN_012084 0 69 0 0 77 ptg000008l:4983532-4984730 D8VNS8 8.19e-48 Ryncolin-2 Cerberus rynchops (Dog-faced water snake) NA GO:0005576; GO:0090729 32900 FUN_012083 178 61 72 86 0 ptg000008l:4942032-4961308 Q5DU56 4.61e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32901 FUN_012082 272 1191 120 18 5 ptg000008l:4935392-4939115 Q5DU56 5.63e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32902 FUN_012081 246 818 82 27 0 ptg000008l:4923019-4926545 Q5DU56 1.49e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 32903 FUN_012080 116 0 18 0 0 NA NA NA NA NA NA NA 32904 FUN_012089 0 0 34 14 0 NA NA NA NA NA NA NA 32905 FUN_012088 19 23 87 40 104 ptg000008l:4998616-5000162 A2AV25 1.9e-62 Fibrinogen C domain-containing protein 1 Mus musculus (Mouse) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0008061; GO:0016020; GO:0046872; GO:0062023 32906 FUN_000859 286 159 104 248 197 ntLink_6:5415047-5419996 Q80UM7 4.36e-161 Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glucosidase 1) (Glycoprotein-processing glucosidase I) Mus musculus (Mouse) oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487] GO:0004573; GO:0005783; GO:0005789; GO:0006487; GO:0009311 32907 FUN_000858 73 0 295 314 837 NA NA NA NA NA NA NA 32908 FUN_000857 9718 10267 7756 9443 6302 NA NA NA NA NA NA NA 32909 FUN_000856 575 266 342 343 353 NA NA NA NA NA NA NA 32910 FUN_043003 2675 1321 1041 2316 2171 NA NA NA NA NA NA NA 32911 FUN_009487 98 52 56 70 24 NA NA NA NA NA NA NA 32912 FUN_022804 5575 4571 2517 3629 2717 NA NA NA NA NA NA NA 32913 FUN_009481 35 11 56 25 0 NA NA NA NA NA NA NA 32914 FUN_022808 0 0 0 12 0 NA NA NA NA NA NA NA 32915 FUN_022809 288 73 123 294 325 NA NA NA NA NA NA NA 32916 FUN_009489 62 0 41 0 0 NA NA NA NA NA NA NA 32917 FUN_009488 2164 4007 1906 1457 1390 NA NA NA NA NA NA NA 32918 FUN_029782 21 0 20 88 0 NA NA NA NA NA NA NA 32919 FUN_029783 40 0 3 126 0 NA NA NA NA NA NA NA 32920 FUN_029781 23 0 9 0 33 NA NA NA NA NA NA NA 32921 FUN_009392 13 186 0 28 0 NA NA NA NA NA NA NA 32922 FUN_016353 2690 1361 924 1641 1638 NA NA NA NA NA NA NA 32923 FUN_016352 660 354 403 552 696 ptg000011l:1999205-2003651 Q8CI75 0 DIS3-like exonuclease 2 (EC 3.1.13.-) Mus musculus (Mouse) cell division [GO:0051301]; miRNA catabolic process [GO:0010587]; mitotic cell cycle [GO:0000278]; mitotic sister chromatid separation [GO:0051306]; mRNA catabolic process [GO:0006402]; negative regulation of cell population proliferation [GO:0008285]; nuclear-transcribed mRNA catabolic process, exonucleolytic [GO:0000291]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyuridylation-dependent mRNA catabolic process [GO:1990074]; stem cell population maintenance [GO:0019827] GO:0000175; GO:0000178; GO:0000278; GO:0000287; GO:0000291; GO:0000932; GO:0004540; GO:0005737; GO:0006402; GO:0008266; GO:0008285; GO:0010587; GO:0019827; GO:0034427; GO:0051301; GO:0051306; GO:1990074 32924 FUN_016351 2822 1744 960 1959 2349 NA NA NA NA NA NA NA 32925 FUN_016350 2272 1353 789 2023 1645 ptg000011l:1978733-1980459 Q02446 1.31e-68 Transcription factor Sp4 (SPR-1) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000978; GO:0000981; GO:0005654; GO:0005829; GO:0006357; GO:0042802; GO:0043565; GO:0046872 32926 FUN_016357 2748 1312 830 1848 1446 NA NA NA NA NA NA NA 32927 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 2.64e-31 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32928 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 6.82e-31 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32929 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 4.41e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32930 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 9.8e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32931 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 1.28e-24 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32932 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 7.02e-23 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32933 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 1.24e-21 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32934 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 2.07e-21 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32935 FUN_016356 84 126 0 118 203 ptg000011l:2104901-2138564 Q8VI56 4.62e-21 Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan) Mus musculus (Mouse) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32936 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 5.4e-145 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32937 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 2.07e-144 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32938 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 5.19e-142 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32939 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 8.01e-142 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32940 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 1.18e-141 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32941 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 6.96e-139 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32942 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 8.63e-122 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32943 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 7.83e-69 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32944 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 1.33e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32945 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 2.7e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32946 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 1.03e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32947 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 1.22e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32948 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 1.98e-64 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32949 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 3.04e-63 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32950 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 9.03e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32951 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 5.13e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32952 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 4.03e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32953 FUN_016355 616 361 10 616 1318 ptg000011l:2055007-2103081 P10079 4.39e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 32954 FUN_016354 4031 3653 3068 5294 3017 ptg000011l:2017199-2047311 O75096 2.06e-29 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32955 FUN_016354 4031 3653 3068 5294 3017 ptg000011l:2017199-2047311 O75096 7.61e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32956 FUN_016354 4031 3653 3068 5294 3017 ptg000011l:2017199-2047311 O75096 5.34e-27 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32957 FUN_016354 4031 3653 3068 5294 3017 ptg000011l:2017199-2047311 O75096 1.35e-25 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32958 FUN_016354 4031 3653 3068 5294 3017 ptg000011l:2017199-2047311 O75096 3.23e-21 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Homo sapiens (Human) amyloid-beta clearance by cellular catabolic process [GO:0150094]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; proximal/distal pattern formation [GO:0009954]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0044853; GO:0048699; GO:0048813; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 32959 FUN_041208 0 0 0 0 71 NA NA NA NA NA NA NA 32960 FUN_016359 237 208 67 525 328 NA NA NA NA NA NA NA 32961 FUN_016358 2182 1544 892 2085 1935 NA NA NA NA NA NA NA 32962 FUN_028788 0 12 0 6 11 ptg000022l:3999422-4006560 Q96AY4 5.73e-176 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32963 FUN_028788 0 12 0 6 11 ptg000022l:3999422-4006560 Q96AY4 4.85e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32964 FUN_028788 0 12 0 6 11 ptg000022l:3999422-4006560 Q96AY4 9.9e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32965 FUN_028788 0 12 0 6 11 ptg000022l:3999422-4006560 Q96AY4 2.55e-97 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32966 FUN_028788 0 12 0 6 11 ptg000022l:3999422-4006560 Q96AY4 2.4e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 32967 FUN_026329 33 0 3 0 0 NA NA NA NA NA NA NA 32968 FUN_026328 128 0 4 7 0 NA NA NA NA NA NA NA 32969 FUN_028781 109 10 55 104 18 NA NA NA NA NA NA NA 32970 FUN_028780 57 37 147 39 58 NA NA NA NA NA NA NA 32971 FUN_026327 94 45 127 104 31 NA NA NA NA NA NA NA 32972 FUN_026326 0 0 85 0 0 NA NA NA NA NA NA NA 32973 FUN_028785 0 0 17 0 21 NA NA NA NA NA NA NA 32974 FUN_025672 4958 5250 2684 4562 4243 NA NA NA NA NA NA NA 32975 FUN_025673 4925 3337 2724 3331 2826 ptg000019l:5520581-5561182 C3YWU0 2.66e-37 Alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase) Branchiostoma floridae (Florida lancelet) (Amphioxus) fucose metabolic process [GO:0006004]; glycoside catabolic process [GO:0016139] GO:0004560; GO:0005576; GO:0005764; GO:0006004; GO:0016139 32976 FUN_025670 3235 2020 2006 2790 2922 ptg000019l:5463897-5476305 P50542 6.29e-36 Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1) Homo sapiens (Human) cell development [GO:0048468]; cerebral cortex cell migration [GO:0021795]; cerebral cortex neuron differentiation [GO:0021895]; endoplasmic reticulum organization [GO:0007029]; fatty acid beta-oxidation [GO:0006635]; mitochondrial membrane organization [GO:0007006]; negative regulation of protein-containing complex assembly [GO:0031333]; neuromuscular process [GO:0050905]; neuron migration [GO:0001764]; pexophagy [GO:0000425]; positive regulation of multicellular organism growth [GO:0040018]; protein import into peroxisome matrix [GO:0016558]; protein import into peroxisome matrix, docking [GO:0016560]; protein import into peroxisome matrix, receptor recycling [GO:0016562]; protein import into peroxisome matrix, substrate release [GO:0044721]; protein import into peroxisome matrix, translocation [GO:0016561]; protein import into peroxisome membrane [GO:0045046]; protein targeting to peroxisome [GO:0006625]; protein tetramerization [GO:0051262]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000268; GO:0000425; GO:0001764; GO:0005052; GO:0005737; GO:0005739; GO:0005777; GO:0005778; GO:0005782; GO:0005794; GO:0005829; GO:0006625; GO:0006635; GO:0007006; GO:0007029; GO:0008022; GO:0016020; GO:0016558; GO:0016560; GO:0016561; GO:0016562; GO:0019899; GO:0021795; GO:0021895; GO:0031267; GO:0031333; GO:0032991; GO:0033328; GO:0040018; GO:0044183; GO:0044721; GO:0045046; GO:0047485; GO:0048468; GO:0050905; GO:0051262; GO:0140597 32977 FUN_025671 1566 1116 789 901 1004 NA NA NA NA NA NA NA 32978 FUN_025676 587 306 315 704 648 NA NA NA NA NA NA NA 32979 FUN_025677 321 229 239 242 407 ptg000019l:5595608-5598602 Q21565 1.12e-31 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 32980 FUN_025677 321 229 239 242 407 ptg000019l:5595608-5598602 Q21565 1.23e-22 Putative ammonium transporter 3 Caenorhabditis elegans ammonium homeostasis [GO:0097272]; ammonium transmembrane transport [GO:0072488] GO:0005886; GO:0008519; GO:0072488; GO:0097272 32981 FUN_025674 496 449 317 536 666 NA NA NA NA NA NA NA 32982 FUN_025675 199 84 183 198 239 NA NA NA NA NA NA NA 32983 FUN_025678 123 135 37 216 133 ptg000019l:5607522-5611418 P49338 2.33e-54 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 32984 FUN_025678 123 135 37 216 133 ptg000019l:5607522-5611418 P49338 1.99e-24 Protein Wnt-4 (XWnt-4) Xenopus laevis (African clawed frog) embryonic pattern specification [GO:0009880]; glomus development [GO:0072013]; nephrostome development [GO:0039018]; pronephric nephron tubule development [GO:0039020]; Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0009880; GO:0016055; GO:0039018; GO:0039020; GO:0072013 32985 FUN_025679 101 42 74 86 199 ptg000019l:5627536-5629794 P47793 2.04e-63 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 32986 FUN_025679 101 42 74 86 199 ptg000019l:5627536-5629794 P47793 2.85e-25 Protein Wnt-4a Danio rerio (Zebrafish) (Brachydanio rerio) canonical Wnt signaling pathway [GO:0060070]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; embryonic viscerocranium morphogenesis [GO:0048703]; habenula development [GO:0021986]; heart development [GO:0007507]; neuron differentiation [GO:0030182]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of axon extension involved in axon guidance [GO:0048841]; sensory epithelium regeneration [GO:0070654] GO:0005109; GO:0005125; GO:0005615; GO:0007507; GO:0021986; GO:0030182; GO:0042074; GO:0045165; GO:0045893; GO:0048703; GO:0048841; GO:0060070; GO:0070654 32987 FUN_017750 2 3 19 17 138 NA NA NA NA NA NA NA 32988 FUN_017752 5 0 0 53 52 NA NA NA NA NA NA NA 32989 FUN_017754 3576 1541 1222 4566 1083 NA NA NA NA NA NA NA 32990 FUN_017755 3450 647 1543 3704 593 NA NA NA NA NA NA NA 32991 FUN_017756 23796 17835 14360 19593 9623 NA NA NA NA NA NA NA 32992 FUN_017757 1722 1796 1141 1609 1579 NA NA NA NA NA NA NA 32993 FUN_017758 2747 1958 1741 2830 2800 ptg000012l:120549-126205 Q9I8C7 1.95e-49 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 32994 FUN_017759 1957 1223 2357 2166 2365 ptg000012l:127648-148295 P25155 6.28e-21 Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Virus-activating protease) (VAP) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain] Gallus gallus (Chicken) blood coagulation [GO:0007596]; positive regulation of protein kinase B signaling [GO:0051897]; proteolysis [GO:0006508] GO:0004252; GO:0005509; GO:0005543; GO:0005615; GO:0006508; GO:0007596; GO:0051897 32995 FUN_011917 1471 1575 1008 1009 1258 NA NA NA NA NA NA NA 32996 FUN_026497 485 410 456 44 72 NA NA NA NA NA NA NA 32997 FUN_028432 0 2 0 120 0 NA NA NA NA NA NA NA 32998 FUN_028431 0 0 0 76 0 NA NA NA NA NA NA NA 32999 FUN_026494 5671 3024 2991 5893 4166 NA NA NA NA NA NA NA 33000 FUN_026493 48 125 48 77 63 NA NA NA NA NA NA NA 33001 FUN_026492 840 1482 854 501 408 NA NA NA NA NA NA NA 33002 FUN_026491 8313 8716 3217 7487 3707 ptg000020l:9529356-9532515 E1B836 1.7e-32 Enkurin Bos taurus (Bovine) establishment of left/right asymmetry [GO:0061966]; flagellated sperm motility [GO:0030317] GO:0001669; GO:0005516; GO:0005879; GO:0017124; GO:0030317; GO:0061966; GO:0097228; GO:0097728 33003 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 6.38e-54 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33004 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 6.38e-54 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33005 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 6.38e-54 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33006 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 5.14e-46 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33007 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 3.28e-30 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33008 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 4.63e-28 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33009 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 1.41e-27 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33010 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 7.35e-25 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33011 FUN_026490 16254 9953 10212 18506 14347 ptg000020l:9500160-9526655 Q99NB9 4.69e-24 Splicing factor 3B subunit 1 (Pre-mRNA-splicing factor SF3b 155 kDa subunit) (SF3b155) (Spliceosome-associated protein 155) (SAP 155) Mus musculus (Mouse) anterior/posterior pattern specification [GO:0009952]; blastocyst formation [GO:0001825]; chromatin remodeling [GO:0006338]; mRNA splicing, via spliceosome [GO:0000398]; positive regulation of histone acetylation [GO:0035066]; positive regulation of transcription by RNA polymerase I [GO:0045943]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription by RNA polymerase III [GO:0045945]; spliceosomal complex assembly [GO:0000245] GO:0000245; GO:0000398; GO:0000785; GO:0001825; GO:0003682; GO:0003723; GO:0003729; GO:0005634; GO:0005684; GO:0005686; GO:0005689; GO:0005730; GO:0006338; GO:0009952; GO:0016363; GO:0016607; GO:0030532; GO:0034693; GO:0035066; GO:0045943; GO:0045944; GO:0045945; GO:0071004; GO:0071005; GO:0071013; GO:0110016; GO:1990935 33012 FUN_026499 1196 0 382 142 825 ptg000020l:9736028-9745084 P35033 1.44e-34 Trypsin-3 (EC 3.4.21.4) (Trypsin III) Salmo salar (Atlantic salmon) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586; GO:0046872 33013 FUN_026498 934 213 649 731 338 NA NA NA NA NA NA NA 33014 FUN_022376 3869 3207 894 1364 2536 NA NA NA NA NA NA NA 33015 FUN_022377 418 243 377 198 427 NA NA NA NA NA NA NA 33016 FUN_022374 1423 939 375 1512 1021 NA NA NA NA NA NA NA 33017 FUN_013803 733 568 114 228 645 NA NA NA NA NA NA NA 33018 FUN_022373 0 0 0 0 53 NA NA NA NA NA NA NA 33019 FUN_022370 47 13 7 19 43 ptg000016l:8252095-8253407 P97292 2.38e-32 Histamine H2 receptor (H2R) (HH2R) (Gastric receptor I) Mus musculus (Mouse) chemical synaptic transmission [GO:0007268]; digestive tract development [GO:0048565]; epithelial cell morphogenesis [GO:0003382]; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [GO:0007187]; gastric acid secretion [GO:0001696]; gastrin-induced gastric acid secretion [GO:0001698]; gland development [GO:0048732]; histamine-induced gastric acid secretion [GO:0001697]; memory [GO:0007613]; negative regulation of arachidonic acid secretion [GO:1900139]; positive regulation of vasoconstriction [GO:0045907]; regulation of synaptic plasticity [GO:0048167]; toxin transport [GO:1901998]; visual learning [GO:0008542] GO:0001696; GO:0001697; GO:0001698; GO:0003382; GO:0004969; GO:0004993; GO:0005886; GO:0007187; GO:0007268; GO:0007613; GO:0008542; GO:0016020; GO:0030425; GO:0030594; GO:0045202; GO:0045907; GO:0048167; GO:0048565; GO:0048732; GO:1900139; GO:1901363; GO:1901998 33020 FUN_022371 1050 500 770 878 843 ptg000016l:8256975-8265548 P34678 2.17e-50 Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (GalNAc-T1) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) (pp-GaNTase 3) Caenorhabditis elegans protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018243; GO:0030246; GO:0046872 33021 FUN_022371 1050 500 770 878 843 ptg000016l:8256975-8265548 P34678 4.65e-22 Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (GalNAc-T1) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) (pp-GaNTase 3) Caenorhabditis elegans protein O-linked glycosylation [GO:0006493]; protein O-linked glycosylation via threonine [GO:0018243] GO:0000139; GO:0004653; GO:0005794; GO:0006493; GO:0018243; GO:0030246; GO:0046872 33022 FUN_000530 0 9 0 0 12 NA NA NA NA NA NA NA 33023 FUN_022378 1143 784 500 1736 1442 NA NA NA NA NA NA NA 33024 FUN_022379 2598 1482 1528 3075 2247 NA NA NA NA NA NA NA 33025 FUN_011978 108 60 21 186 106 NA NA NA NA NA NA NA 33026 FUN_011979 0 0 0 0 20 ptg000008l:3784620-3789362 Q9QYS2 4.67e-94 Metabotropic glutamate receptor 3 (mGluR3) Mus musculus (Mouse) G protein-coupled glutamate receptor signaling pathway [GO:0007216]; gene expression [GO:0010467]; modulation of chemical synaptic transmission [GO:0050804]; postsynaptic modulation of chemical synaptic transmission [GO:0099170]; regulation of sensory perception of pain [GO:0051930]; regulation of synaptic transmission, glutamatergic [GO:0051966]; sensory perception of pain [GO:0019233]; synaptic transmission, glutamatergic [GO:0035249] GO:0001640; GO:0001641; GO:0005246; GO:0005886; GO:0007216; GO:0010467; GO:0014069; GO:0019233; GO:0030424; GO:0035249; GO:0042734; GO:0043005; GO:0043197; GO:0045211; GO:0048786; GO:0050804; GO:0051930; GO:0051966; GO:0097110; GO:0097449; GO:0098978; GO:0099170 33027 FUN_011972 956 605 118 1413 132 NA NA NA NA NA NA NA 33028 FUN_011973 1277 865 614 734 860 NA NA NA NA NA NA NA 33029 FUN_011970 43 36 35 34 104 NA NA NA NA NA NA NA 33030 FUN_011971 0 0 0 10 0 NA NA NA NA NA NA NA 33031 FUN_011976 719 350 585 595 1308 ptg000008l:3763711-3774979 P48442 1.25e-120 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 33032 FUN_011976 719 350 585 595 1308 ptg000008l:3763711-3774979 P48442 1.57e-118 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 33033 FUN_011977 46 0 9 0 6 NA NA NA NA NA NA NA 33034 FUN_011974 2032 1531 1029 1365 1885 NA NA NA NA NA NA NA 33035 FUN_011975 2595 1593 2103 3304 2778 NA NA NA NA NA NA NA 33036 FUN_013707 0 0 0 0 11 NA NA NA NA NA NA NA 33037 FUN_014574 504 139 238 739 408 NA NA NA NA NA NA NA 33038 FUN_001551 501 419 268 394 703 NA NA NA NA NA NA NA 33039 FUN_014576 9 0 0 0 0 NA NA NA NA NA NA NA 33040 FUN_014571 1349 1198 656 1271 371 NA NA NA NA NA NA NA 33041 FUN_001553 3091 3570 2447 1725 1946 NA NA NA NA NA NA NA 33042 FUN_014570 3360 2268 3301 7298 3877 NA NA NA NA NA NA NA 33043 FUN_014573 2324 940 1284 1960 1369 NA NA NA NA NA NA NA 33044 FUN_001555 183 108 228 347 143 NA NA NA NA NA NA NA 33045 FUN_014572 1254 668 464 883 229 ptg000009l:1226755-1228254 Q6DDL7 4.58e-37 Protein unc-93 homolog A (Unc-93A) Xenopus laevis (African clawed frog) NA GO:0016020 33046 FUN_014572 1254 668 464 883 229 ptg000009l:1226755-1228254 Q6DDL7 4.1e-33 Protein unc-93 homolog A (Unc-93A) Xenopus laevis (African clawed frog) NA GO:0016020 33047 FUN_019615 0 21 0 0 0 NA NA NA NA NA NA NA 33048 FUN_014225 0 0 12 0 0 NA NA NA NA NA NA NA 33049 FUN_019612 90 0 14 0 27 NA NA NA NA NA NA NA 33050 FUN_014227 12 0 0 0 0 NA NA NA NA NA NA NA 33051 FUN_044146 3 2 12 3 85 NA NA NA NA NA NA NA 33052 FUN_014229 5 11 4 28 26 NA NA NA NA NA NA NA 33053 FUN_044148 61 243 103 201 461 NA NA NA NA NA NA NA 33054 FUN_001556 182 32 76 210 243 ntLink_6:13724737-13725757 P35406 1.19e-21 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 33055 FUN_019619 0 0 14 0 120 NA NA NA NA NA NA NA 33056 FUN_019618 0 0 0 0 30 NA NA NA NA NA NA NA 33057 FUN_024235 16 177 112 283 120 NA NA NA NA NA NA NA 33058 FUN_024237 85 61 109 207 75 ptg000018l:3795255-3800270 Q8K3Z0 8.68e-33 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 33059 FUN_024236 7 25 70 70 41 NA NA NA NA NA NA NA 33060 FUN_024231 0 94 98 118 200 NA NA NA NA NA NA NA 33061 FUN_024233 29 84 62 176 379 ptg000018l:3768235-3771970 B0FPE9 1.44e-44 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Macaca mulatta (Rhesus macaque) detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727] GO:0002674; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005783; GO:0006954; GO:0009595; GO:0016020; GO:0016887; GO:0031021; GO:0032731; GO:0032753; GO:0035591; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045630; GO:0045944; GO:0050727; GO:0050729; GO:0051260; GO:0070273; GO:0072559; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000553 33062 FUN_024232 64 240 72 127 3 ptg000018l:3750614-3756009 Q7RTR2 1.12e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33063 FUN_010028 17 0 0 8 30 NA NA NA NA NA NA NA 33064 FUN_024239 1 0 2 79 16 NA NA NA NA NA NA NA 33065 FUN_024238 22 131 172 254 245 NA NA NA NA NA NA NA 33066 FUN_025610 4381 2168 2821 4291 2726 NA NA NA NA NA NA NA 33067 FUN_022643 148 87 191 135 299 NA NA NA NA NA NA NA 33068 FUN_041486 4914 3056 2277 5873 5512 NA NA NA NA NA NA NA 33069 FUN_022646 781 344 421 496 449 NA NA NA NA NA NA NA 33070 FUN_022647 3686 1939 1398 2771 1891 NA NA NA NA NA NA NA 33071 FUN_032588 0 19 0 0 0 NA NA NA NA NA NA NA 33072 FUN_041368 739 426 770 994 750 NA NA NA NA NA NA NA 33073 FUN_021777 3 15 40 14 59 NA NA NA NA NA NA NA 33074 FUN_037902 198 218 120 687 256 NA NA NA NA NA NA NA 33075 FUN_021779 19 0 38 0 55 NA NA NA NA NA NA NA 33076 FUN_021778 0 13 0 0 0 NA NA NA NA NA NA NA 33077 FUN_005978 0 3 0 4 12 NA NA NA NA NA NA NA 33078 FUN_037977 522 212 276 445 581 ptg000027l:1105916-1131511 Q6ZPG2 9.56e-41 WD repeat-containing protein 90 Mus musculus (Mouse) cilium assembly [GO:0060271] GO:0005737; GO:0005814; GO:0060271 33079 FUN_037977 522 212 276 445 581 ptg000027l:1105916-1131511 Q6ZPG2 9.56e-41 WD repeat-containing protein 90 Mus musculus (Mouse) cilium assembly [GO:0060271] GO:0005737; GO:0005814; GO:0060271 33080 FUN_037977 522 212 276 445 581 ptg000027l:1105916-1131511 Q6ZPG2 2.58e-26 WD repeat-containing protein 90 Mus musculus (Mouse) cilium assembly [GO:0060271] GO:0005737; GO:0005814; GO:0060271 33081 FUN_008116 80 35 0 0 0 ptg000002l:8212899-8216363 Q71MM5 8.19e-28 Doublesex- and mab-3-related transcription factor 1 Danio rerio (Zebrafish) (Brachydanio rerio) germ cell development [GO:0007281]; male germ cell proliferation [GO:0002176]; male gonad development [GO:0008584]; male sex determination [GO:0030238]; regulation of transcription by RNA polymerase II [GO:0006357]; sex differentiation [GO:0007548] GO:0000978; GO:0000981; GO:0002176; GO:0005634; GO:0006357; GO:0007281; GO:0007548; GO:0008584; GO:0030238; GO:0046872 33082 FUN_024560 564 438 421 464 491 ptg000018l:8330208-8333454 Q56I99 1e-110 Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (SMAD family member 5) (SMAD 5) (Smad5) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0030509; GO:0046872; GO:0060395; GO:0070411; GO:0071144 33083 FUN_024560 564 438 421 464 491 ptg000018l:8330208-8333454 Q56I99 1.21e-55 Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (SMAD family member 5) (SMAD 5) (Smad5) Gallus gallus (Chicken) anatomical structure morphogenesis [GO:0009653]; BMP signaling pathway [GO:0030509]; cell differentiation [GO:0030154]; SMAD protein signal transduction [GO:0060395]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0007179; GO:0009653; GO:0030154; GO:0030509; GO:0046872; GO:0060395; GO:0070411; GO:0071144 33084 FUN_037972 2400 1557 567 1838 657 NA NA NA NA NA NA NA 33085 FUN_024563 12 4 29 1 13 NA NA NA NA NA NA NA 33086 FUN_037973 4276 2572 1756 4004 3293 NA NA NA NA NA NA NA 33087 FUN_024562 1585 590 563 1049 785 NA NA NA NA NA NA NA 33088 FUN_008112 44 18 102 42 103 NA NA NA NA NA NA NA 33089 FUN_008113 0 0 15 14 56 NA NA NA NA NA NA NA 33090 FUN_023959 444 574 324 356 510 ptg000018l:559080-565022 Q7ZXC9 2.74e-31 Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) Xenopus laevis (African clawed frog) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleotide biosynthetic process [GO:0009165]; phosphorylation [GO:0016310]; ribonucleoside monophosphate biosynthetic process [GO:0009156] GO:0000287; GO:0004749; GO:0005524; GO:0006015; GO:0009156; GO:0009165; GO:0016301; GO:0016310; GO:0042803 33091 FUN_023959 444 574 324 356 510 ptg000018l:559080-565022 Q7ZXC9 6.89e-30 Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase II) (PRS-II) Xenopus laevis (African clawed frog) 5-phosphoribose 1-diphosphate biosynthetic process [GO:0006015]; nucleotide biosynthetic process [GO:0009165]; phosphorylation [GO:0016310]; ribonucleoside monophosphate biosynthetic process [GO:0009156] GO:0000287; GO:0004749; GO:0005524; GO:0006015; GO:0009156; GO:0009165; GO:0016301; GO:0016310; GO:0042803 33092 FUN_023958 340 83 129 306 489 NA NA NA NA NA NA NA 33093 FUN_031679 3156 2943 1163 1814 1310 NA NA NA NA NA NA NA 33094 FUN_031678 2383 1689 794 1512 1065 NA NA NA NA NA NA NA 33095 FUN_008110 954 354 403 874 1242 ptg000002l:8129976-8151993 O00339 1.42e-63 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 33096 FUN_008110 954 354 403 874 1242 ptg000002l:8129976-8151993 O00339 9.55e-51 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 33097 FUN_008110 954 354 403 874 1242 ptg000002l:8129976-8151993 O00339 5.37e-33 Matrilin-2 Homo sapiens (Human) extracellular matrix organization [GO:0030198] GO:0005201; GO:0005509; GO:0005576; GO:0030198; GO:0031012; GO:0062023; GO:0120216 33098 FUN_023951 1605 1331 444 1383 936 NA NA NA NA NA NA NA 33099 FUN_023950 5096 2846 2712 4283 3790 ptg000018l:481281-505025 P45481 4.62e-41 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Mus musculus (Mouse) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0016605; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0051091; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 33100 FUN_023950 5096 2846 2712 4283 3790 ptg000018l:481281-505025 P45481 2.53e-31 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Mus musculus (Mouse) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0016605; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0051091; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 33101 FUN_023950 5096 2846 2712 4283 3790 ptg000018l:481281-505025 P45481 3.83e-28 Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-) Mus musculus (Mouse) behavioral response to cocaine [GO:0048148]; cell population proliferation [GO:0008283]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to UV [GO:0034644]; cellular response to virus [GO:0098586]; face morphogenesis [GO:0060325]; germ-line stem cell population maintenance [GO:0030718]; histone acetylation [GO:0016573]; histone glutamine methylation [GO:1990258]; histone modification [GO:0016570]; long-term memory [GO:0007616]; N-terminal peptidyl-lysine acetylation [GO:0018076]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of transcription by RNA polymerase I [GO:0016479]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of viral process [GO:0048525]; positive regulation of cell adhesion molecule production [GO:0060355]; positive regulation of CREB transcription factor activity [GO:0032793]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of gene expression [GO:0010628]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transforming growth factor beta receptor signaling pathway [GO:0030511]; protein acetylation [GO:0006473]; protein destabilization [GO:0031648]; regulation of DNA-templated transcription [GO:0006355]; response to ischemia [GO:0002931]; rhythmic process [GO:0048511] GO:0000122; GO:0000123; GO:0000785; GO:0000940; GO:0000977; GO:0001093; GO:0001223; GO:0002039; GO:0002931; GO:0003677; GO:0003682; GO:0003684; GO:0003713; GO:0003714; GO:0004402; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006355; GO:0006473; GO:0007616; GO:0008140; GO:0008270; GO:0008283; GO:0010628; GO:0016407; GO:0016479; GO:0016570; GO:0016573; GO:0016604; GO:0016605; GO:0018076; GO:0019904; GO:0030511; GO:0030718; GO:0031490; GO:0031648; GO:0032688; GO:0032793; GO:0032991; GO:0034644; GO:0035729; GO:0042975; GO:0043426; GO:0045893; GO:0045944; GO:0046332; GO:0048148; GO:0048511; GO:0048525; GO:0051091; GO:0060090; GO:0060325; GO:0060355; GO:0060999; GO:0061629; GO:0061733; GO:0090575; GO:0097718; GO:0098586; GO:0140297; GO:1900087; GO:1901224; GO:1990258 33102 FUN_031670 7 218 236 342 151 NA NA NA NA NA NA NA 33103 FUN_023955 2232 1763 739 1407 488 ptg000018l:535207-543308 Q58A65 3.5e-25 C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9) Mus musculus (Mouse) lysosome localization [GO:0032418]; negative regulation of dendrite extension [GO:1903860]; negative regulation of neuron differentiation [GO:0045665]; negative regulation of protein phosphorylation [GO:0001933]; positive regulation of cell migration [GO:0030335]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of neuron differentiation [GO:0045666]; retrograde transport, endosome to Golgi [GO:0042147]; striated muscle cell differentiation [GO:0051146]; vesicle-mediated transport [GO:0016192] GO:0001933; GO:0005078; GO:0005737; GO:0005765; GO:0005829; GO:0008432; GO:0016192; GO:0019894; GO:0030159; GO:0030335; GO:0032418; GO:0034451; GO:0042147; GO:0042802; GO:0043410; GO:0045665; GO:0045666; GO:0048471; GO:0051146; GO:1903860 33104 FUN_023954 329 314 300 496 391 NA NA NA NA NA NA NA 33105 FUN_023957 112 19 51 54 149 NA NA NA NA NA NA NA 33106 FUN_031674 156 108 133 237 246 NA NA NA NA NA NA NA 33107 FUN_039467 0 0 0 0 12 NA NA NA NA NA NA NA 33108 FUN_039464 0 0 0 0 59 NA NA NA NA NA NA NA 33109 FUN_039465 0 0 0 0 18 NA NA NA NA NA NA NA 33110 FUN_039460 42 0 0 0 7 NA NA NA NA NA NA NA 33111 FUN_014246 22 0 0 0 0 NA NA NA NA NA NA NA 33112 FUN_044125 6 2 17 4 119 NA NA NA NA NA NA NA 33113 FUN_043168 71 90 53 107 96 NA NA NA NA NA NA NA 33114 FUN_044124 58 176 69 121 404 NA NA NA NA NA NA NA 33115 FUN_044123 66 211 78 180 453 NA NA NA NA NA NA NA 33116 FUN_023186 3348 1595 1000 2233 1845 NA NA NA NA NA NA NA 33117 FUN_012784 3123 2458 1536 3171 2732 NA NA NA NA NA NA NA 33118 FUN_044121 0 3 0 0 13 NA NA NA NA NA NA NA 33119 FUN_023187 411 293 334 490 660 NA NA NA NA NA NA NA 33120 FUN_044120 48 169 68 152 343 NA NA NA NA NA NA NA 33121 FUN_023184 690 368 323 538 503 NA NA NA NA NA NA NA 33122 FUN_043169 1185 989 688 2076 2529 NA NA NA NA NA NA NA 33123 FUN_026863 0 0 11 0 0 NA NA NA NA NA NA NA 33124 FUN_026860 0 0 0 16 0 NA NA NA NA NA NA NA 33125 FUN_039288 0 8 9 18 52 NA NA NA NA NA NA NA 33126 FUN_023180 723 1081 479 682 697 NA NA NA NA NA NA NA 33127 FUN_039282 845 435 274 189 287 NA NA NA NA NA NA NA 33128 FUN_039283 252 127 17 152 210 ptg000028l:272717-277699 Q96AY4 2.23e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33129 FUN_039283 252 127 17 152 210 ptg000028l:272717-277699 Q96AY4 6.07e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33130 FUN_039283 252 127 17 152 210 ptg000028l:272717-277699 Q96AY4 1.74e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33131 FUN_039283 252 127 17 152 210 ptg000028l:272717-277699 Q96AY4 2.3e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33132 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 2.29e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33133 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 1.26e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33134 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 3.51e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33135 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 8.92e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33136 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 4.18e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33137 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 4.06e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33138 FUN_039280 403 269 13 140 474 ptg000028l:226669-236773 Q96AY4 4.84e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33139 FUN_023181 2984 4620 2024 2295 997 NA NA NA NA NA NA NA 33140 FUN_039287 959 687 284 529 790 ptg000028l:324934-331750 Q9VPC0 3.06e-24 Serine/threonine-protein kinase PITSLRE (EC 2.7.11.22) (Cell division cycle 2-like) Drosophila melanogaster (Fruit fly) cell cycle [GO:0007049]; positive regulation of antimicrobial peptide production [GO:0002225]; positive regulation of Toll signaling pathway [GO:0045752]; protein phosphorylation [GO:0006468]; regulation of mitotic cell cycle [GO:0007346] GO:0002225; GO:0004674; GO:0004693; GO:0004713; GO:0005524; GO:0005634; GO:0006468; GO:0007049; GO:0007346; GO:0045752; GO:0106310 33141 FUN_039284 1206 831 120 572 480 NA NA NA NA NA NA NA 33142 FUN_039285 152 370 113 154 101 NA NA NA NA NA NA NA 33143 FUN_014249 20 0 26 0 0 NA NA NA NA NA NA NA 33144 FUN_037538 0 0 0 0 13 NA NA NA NA NA NA NA 33145 FUN_037539 0 0 0 0 23 NA NA NA NA NA NA NA 33146 FUN_037536 56 37 44 79 46 NA NA NA NA NA NA NA 33147 FUN_037537 36 525 430 308 127 NA NA NA NA NA NA NA 33148 FUN_037534 0 0 0 9 0 NA NA NA NA NA NA NA 33149 FUN_037535 50 16 107 0 159 NA NA NA NA NA NA NA 33150 FUN_037532 402 150 134 224 520 NA NA NA NA NA NA NA 33151 FUN_037533 4 0 7 2 153 NA NA NA NA NA NA NA 33152 FUN_037530 16 50 68 110 44 NA NA NA NA NA NA NA 33153 FUN_037531 2 26 3 15 19 NA NA NA NA NA NA NA 33154 FUN_037280 0 41 0 14 0 NA NA NA NA NA NA NA 33155 FUN_037281 164 85 136 111 85 ptg000026l:8056001-8058659 Q12955 1.01e-110 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 33156 FUN_037281 164 85 136 111 85 ptg000026l:8056001-8058659 Q12955 6.13e-107 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 33157 FUN_037281 164 85 136 111 85 ptg000026l:8056001-8058659 Q12955 4.71e-95 Ankyrin-3 (ANK-3) (Ankyrin-G) Homo sapiens (Human) axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; establishment of protein localization [GO:0045184]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; signal transduction [GO:0007165] GO:0000281; GO:0005200; GO:0005764; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007528; GO:0008092; GO:0008093; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030425; GO:0030507; GO:0030674; GO:0031594; GO:0033268; GO:0034112; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045184; GO:0045211; GO:0045296; GO:0045838; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:1900827; GO:1902260; GO:2000651; GO:2001259 33158 FUN_037282 27 31 68 24 133 NA NA NA NA NA NA NA 33159 FUN_037284 0 15 43 0 8 NA NA NA NA NA NA NA 33160 FUN_037285 845 590 28 879 1587 NA NA NA NA NA NA NA 33161 FUN_037286 5469 3634 2822 4920 3347 NA NA NA NA NA NA NA 33162 FUN_037287 50 43 0 95 69 NA NA NA NA NA NA NA 33163 FUN_037288 5180 4404 2639 4842 2964 NA NA NA NA NA NA NA 33164 FUN_001270 1257 1049 545 732 661 ntLink_6:10584107-10591527 Q9NWT6 3.86e-68 Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase) Homo sapiens (Human) negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061428]; peptidyl-aspartic acid hydroxylation [GO:0042264]; peptidyl-histidine hydroxylation [GO:0036138]; positive regulation of myoblast differentiation [GO:0045663]; positive regulation of vasculogenesis [GO:2001214] GO:0005112; GO:0005654; GO:0005737; GO:0005829; GO:0008198; GO:0008270; GO:0016706; GO:0019826; GO:0031406; GO:0036138; GO:0036139; GO:0036140; GO:0042264; GO:0042803; GO:0043433; GO:0045663; GO:0045746; GO:0048471; GO:0051059; GO:0061428; GO:0062101; GO:0071532; GO:2001214 33165 FUN_001271 355 195 82 162 326 NA NA NA NA NA NA NA 33166 FUN_001272 7475 5019 4235 6568 4788 NA NA NA NA NA NA NA 33167 FUN_001274 781 164 137 202 251 ntLink_6:10621505-10665905 P14381 2.26e-21 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 33168 FUN_001275 229 138 193 166 210 NA NA NA NA NA NA NA 33169 FUN_001276 18 0 19 3 65 NA NA NA NA NA NA NA 33170 FUN_001279 27 0 0 1 1 NA NA NA NA NA NA NA 33171 FUN_022397 4013 3038 2070 3338 1999 NA NA NA NA NA NA NA 33172 FUN_025881 3422 4957 1253 2301 2397 NA NA NA NA NA NA NA 33173 FUN_025880 44 0 0 0 43 NA NA NA NA NA NA NA 33174 FUN_025883 499 579 392 754 848 NA NA NA NA NA NA NA 33175 FUN_025882 32 0 18 45 55 NA NA NA NA NA NA NA 33176 FUN_025885 804 506 715 71 449 NA NA NA NA NA NA NA 33177 FUN_025884 515 491 552 166 506 NA NA NA NA NA NA NA 33178 FUN_025887 417 173 207 266 1045 ptg000020l:1639832-1651553 P59046 3.76e-56 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 33179 FUN_025886 543 151 286 276 857 ptg000020l:1627587-1633314 P59046 2.67e-56 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727]; regulation of interleukin-18 production [GO:0032661]; signal transduction [GO:0007165] GO:0001818; GO:0005524; GO:0005737; GO:0005829; GO:0006919; GO:0007165; GO:0008656; GO:0009968; GO:0031953; GO:0032088; GO:0032661; GO:0032692; GO:0032715; GO:0032731; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0050729; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 33180 FUN_025889 528 313 738 419 841 ptg000020l:1656781-1665066 Q3URQ0 1.04e-35 Testis-expressed protein 10 Mus musculus (Mouse) NA GO:0005634; GO:0005654; GO:0005730; GO:0005739; GO:0071339 33181 FUN_025888 96 34 33 20 46 NA NA NA NA NA NA NA 33182 FUN_023353 2507 1185 1767 1358 1800 NA NA NA NA NA NA NA 33183 FUN_004211 651 234 43 327 174 ntLink_8:20800059-20800413 Q9D5I4 1.49e-25 Dynein light chain Tctex-type 5 (Tctex1 domain-containing protein 1) Mus musculus (Mouse) microtubule-based movement [GO:0007018] GO:0005737; GO:0005868; GO:0007018; GO:0045505 33184 FUN_004210 251 199 187 257 238 ntLink_8:20793731-20798299 Q15717 3.11e-59 ELAV-like protein 1 (Hu-antigen R) (HuR) Homo sapiens (Human) 3'-UTR-mediated mRNA stabilization [GO:0070935]; mRNA stabilization [GO:0048255]; negative regulation of miRNA-mediated gene silencing [GO:0060965]; positive regulation of translation [GO:0045727]; post-transcriptional gene silencing [GO:0016441]; protein homooligomerization [GO:0051260]; protein import into nucleus [GO:0006606]; regulation of stem cell population maintenance [GO:2000036] GO:0000932; GO:0003723; GO:0003725; GO:0003729; GO:0003730; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005829; GO:0006606; GO:0010494; GO:0016020; GO:0016441; GO:0016528; GO:0019901; GO:0031410; GO:0035198; GO:0035925; GO:0042803; GO:0045727; GO:0048255; GO:0051260; GO:0060965; GO:0070935; GO:0098794; GO:0098978; GO:0106222; GO:1990904; GO:2000036 33185 FUN_004213 250 171 247 147 474 NA NA NA NA NA NA NA 33186 FUN_004212 798 1454 344 922 310 ntLink_8:20802807-20803461 A2VDD2 6.73e-37 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 33187 FUN_004217 17 0 0 0 0 NA NA NA NA NA NA NA 33188 FUN_018209 4 43 0 0 7 NA NA NA NA NA NA NA 33189 FUN_018208 10 1 11 4 1 NA NA NA NA NA NA NA 33190 FUN_018207 558 313 51 290 21 ptg000012l:5984273-5993593 Q9Y6N7 4.88e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 33191 FUN_023343 259 191 325 122 215 NA NA NA NA NA NA NA 33192 FUN_018204 318 38 391 283 136 NA NA NA NA NA NA NA 33193 FUN_018203 372 30 65 226 90 ptg000012l:5901308-5912540 O89026 4.38e-22 Roundabout homolog 1 Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; endocardial cushion formation [GO:0003272]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; kidney development [GO:0001822]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; regulation of dendrite morphogenesis [GO:0048814]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281]; ventricular septum morphogenesis [GO:0060412] GO:0001822; GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0003281; GO:0005737; GO:0005886; GO:0006919; GO:0007156; GO:0007411; GO:0007507; GO:0008046; GO:0008285; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0021891; GO:0030275; GO:0030336; GO:0030424; GO:0030673; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043025; GO:0043406; GO:0048814; GO:0050772; GO:0050925; GO:0060412; GO:0060763; GO:0060976; GO:0070100; GO:1900748 33194 FUN_016368 1399 1178 692 2067 1403 ptg000011l:2283748-2335283 Q8NEV4 4.22e-29 Myosin-IIIa (EC 2.7.11.1) Homo sapiens (Human) cochlea morphogenesis [GO:0090103]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of filopodium assembly [GO:0051491]; protein autophosphorylation [GO:0046777]; regulation of actin filament length [GO:0030832]; response to stimulus [GO:0050896]; sensory perception of sound [GO:0007605]; visual perception [GO:0007601] GO:0000146; GO:0001917; GO:0003779; GO:0004672; GO:0004674; GO:0005516; GO:0005524; GO:0005737; GO:0007601; GO:0007605; GO:0016459; GO:0018105; GO:0030175; GO:0030832; GO:0031941; GO:0032426; GO:0032433; GO:0043531; GO:0046777; GO:0050896; GO:0051491; GO:0060002; GO:0090103; GO:0106310 33195 FUN_018201 127 2 35 50 121 NA NA NA NA NA NA NA 33196 FUN_018200 393 327 591 353 264 ptg000012l:5839615-5853319 Q96AY4 1.4e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33197 FUN_018200 393 327 591 353 264 ptg000012l:5839615-5853319 Q96AY4 6.26e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33198 FUN_018200 393 327 591 353 264 ptg000012l:5839615-5853319 Q96AY4 2.67e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33199 FUN_018200 393 327 591 353 264 ptg000012l:5839615-5853319 Q96AY4 9e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33200 FUN_018200 393 327 591 353 264 ptg000012l:5839615-5853319 Q96AY4 4.25e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33201 FUN_018200 393 327 591 353 264 ptg000012l:5839615-5853319 Q96AY4 2.29e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33202 FUN_029756 2118 1958 1433 2351 2299 NA NA NA NA NA NA NA 33203 FUN_034160 173 79 82 138 108 NA NA NA NA NA NA NA 33204 FUN_034161 182 98 75 80 79 NA NA NA NA NA NA NA 33205 FUN_034162 1367 1324 897 1337 1041 NA NA NA NA NA NA NA 33206 FUN_034163 185 121 93 754 147 NA NA NA NA NA NA NA 33207 FUN_034164 853 670 524 1418 618 ptg000024l:5625656-5626898 Q9Z2L6 2.59e-57 Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) Mus musculus (Mouse) NA GO:0003993; GO:0005788; GO:0005886; GO:0030351; GO:0030352; GO:0034417; GO:0052745; GO:0052826 33208 FUN_034165 9787 6524 2569 4689 2812 NA NA NA NA NA NA NA 33209 FUN_034167 1512 1207 1043 989 778 NA NA NA NA NA NA NA 33210 FUN_016366 278 199 108 440 285 NA NA NA NA NA NA NA 33211 FUN_029758 2155 1457 1469 1970 3089 NA NA NA NA NA NA NA 33212 FUN_040299 2222 1272 1614 3356 2936 NA NA NA NA NA NA NA 33213 FUN_010578 155 28 35 84 72 NA NA NA NA NA NA NA 33214 FUN_019158 52 0 10 0 13 NA NA NA NA NA NA NA 33215 FUN_019159 6 10 5 4 7 NA NA NA NA NA NA NA 33216 FUN_019154 10 0 0 0 3 NA NA NA NA NA NA NA 33217 FUN_019155 553 0 0 210 2 NA NA NA NA NA NA NA 33218 FUN_004144 105 51 134 173 63 NA NA NA NA NA NA NA 33219 FUN_040290 22 38 32 22 51 NA NA NA NA NA NA NA 33220 FUN_040293 6 0 35 33 37 NA NA NA NA NA NA NA 33221 FUN_040292 9 37 46 56 28 NA NA NA NA NA NA NA 33222 FUN_009260 14 33 8 21 46 NA NA NA NA NA NA NA 33223 FUN_010575 2487 2982 1794 9100 6960 ptg000007l:306781-330211 Q3UHK3 8.57e-39 Protein GREB1 Mus musculus (Mouse) NA GO:0016020 33224 FUN_010574 0 1 0 32 38 NA NA NA NA NA NA NA 33225 FUN_030263 20 0 28 4 132 ptg000023l:10483864-10484851 Q6LAF1 6.31e-44 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33226 FUN_030262 5 0 3 0 19 ptg000023l:10482837-10483600 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33227 FUN_030260 4 0 3 0 16 ptg000023l:10478785-10479548 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33228 FUN_030267 4 1 3 0 18 ptg000023l:10493668-10494431 P84239 1.14e-92 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33229 FUN_030265 2 0 5 0 17 ptg000023l:10489616-10490379 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33230 FUN_022589 3548 2766 1399 2206 1866 NA NA NA NA NA NA NA 33231 FUN_030269 4 1 3 0 20 ptg000023l:10497720-10498483 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33232 FUN_040296 1 25 2 0 3 NA NA NA NA NA NA NA 33233 FUN_022588 92 75 55 100 100 NA NA NA NA NA NA NA 33234 FUN_015628 0 6 0 0 0 NA NA NA NA NA NA NA 33235 FUN_002219 4 4 2 1 29 NA NA NA NA NA NA NA 33236 FUN_002218 33 2 19 2 127 NA NA NA NA NA NA NA 33237 FUN_007868 1140 407 429 582 487 NA NA NA NA NA NA NA 33238 FUN_018184 49 0 53 206 91 NA NA NA NA NA NA NA 33239 FUN_007862 14 21 24 8 45 NA NA NA NA NA NA NA 33240 FUN_018186 26 23 25 0 141 NA NA NA NA NA NA NA 33241 FUN_012043 37 45 7 132 49 NA NA NA NA NA NA NA 33242 FUN_018187 380 100 917 486 155 NA NA NA NA NA NA NA 33243 FUN_042724 5 1 6 0 5 NA NA NA NA NA NA NA 33244 FUN_018182 18 119 94 534 407 ptg000012l:5515777-5547552 O89026 8.13e-21 Roundabout homolog 1 Mus musculus (Mouse) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon guidance [GO:0007411]; axon midline choice point recognition [GO:0016199]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; coronary vasculature development [GO:0060976]; endocardial cushion formation [GO:0003272]; heart development [GO:0007507]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; kidney development [GO:0001822]; mammary duct terminal end bud growth [GO:0060763]; negative regulation of cell migration [GO:0030336]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; olfactory bulb interneuron development [GO:0021891]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; regulation of dendrite morphogenesis [GO:0048814]; Roundabout signaling pathway [GO:0035385]; ventricular septum development [GO:0003281]; ventricular septum morphogenesis [GO:0060412] GO:0001822; GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0003281; GO:0005737; GO:0005886; GO:0006919; GO:0007156; GO:0007411; GO:0007507; GO:0008046; GO:0008285; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0021891; GO:0030275; GO:0030336; GO:0030424; GO:0030673; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043025; GO:0043406; GO:0048814; GO:0050772; GO:0050925; GO:0060412; GO:0060763; GO:0060976; GO:0070100; GO:1900748 33245 FUN_007864 1187 911 688 754 857 NA NA NA NA NA NA NA 33246 FUN_040479 767 459 590 380 444 NA NA NA NA NA NA NA 33247 FUN_012045 1555 721 603 585 462 NA NA NA NA NA NA NA 33248 FUN_040475 220 85 102 95 51 NA NA NA NA NA NA NA 33249 FUN_040474 0 0 0 2 34 NA NA NA NA NA NA NA 33250 FUN_040477 2335 2296 1263 1602 983 ptg000031l:9034570-9144126 Q95SX7 5.86e-37 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33251 FUN_040477 2335 2296 1263 1602 983 ptg000031l:9034570-9144126 Q95SX7 3.19e-23 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33252 FUN_040477 2335 2296 1263 1602 983 ptg000031l:9034570-9144126 Q95SX7 3.19e-23 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33253 FUN_040476 0 0 0 0 6 NA NA NA NA NA NA NA 33254 FUN_040471 0 7 0 0 23 NA NA NA NA NA NA NA 33255 FUN_040470 30 12 0 1 1 NA NA NA NA NA NA NA 33256 FUN_040473 524 265 252 288 227 NA NA NA NA NA NA NA 33257 FUN_040472 3063 2865 365 283 3699 NA NA NA NA NA NA NA 33258 FUN_006092 0 0 10 0 0 NA NA NA NA NA NA NA 33259 FUN_042034 1753 2033 1037 1666 1635 NA NA NA NA NA NA NA 33260 FUN_042033 74 84 23 62 79 ptg000035l:9958561-9963337 Q6ZMV8 2.15e-35 Putative zinc finger protein 730 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 33261 FUN_042033 74 84 23 62 79 ptg000035l:9958561-9963337 Q6ZMV8 9.95e-25 Putative zinc finger protein 730 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 33262 FUN_042033 74 84 23 62 79 ptg000035l:9958561-9963337 Q6ZMV8 3.39e-24 Putative zinc finger protein 730 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 33263 FUN_042033 74 84 23 62 79 ptg000035l:9958561-9963337 Q6ZMV8 4.93e-21 Putative zinc finger protein 730 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 33264 FUN_042033 74 84 23 62 79 ptg000035l:9958561-9963337 Q6ZMV8 7.05e-21 Putative zinc finger protein 730 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 33265 FUN_008166 148 51 71 56 86 NA NA NA NA NA NA NA 33266 FUN_042032 694 365 278 545 551 ptg000035l:9953050-9955865 P25931 3.29e-30 RYamide receptor (Neuropeptide Y-like receptor) (NPY-R) Drosophila melanogaster (Fruit fly) G protein-coupled receptor signaling pathway [GO:0007186]; neuropeptide signaling pathway [GO:0007218] GO:0001653; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0016020 33267 FUN_032131 498 1427 2323 3698 677 ptg000023l:29085830-29087737 Q94515 9.9e-107 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 33268 FUN_032130 4677 4611 2627 3061 2408 ptg000023l:29082805-29085768 Q6PBM1 2.88e-44 Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5) Danio rerio (Zebrafish) (Brachydanio rerio) hemopoiesis [GO:0030097]; iron-sulfur cluster assembly [GO:0016226] GO:0005737; GO:0005739; GO:0005759; GO:0016226; GO:0030097; GO:0046872; GO:0051537 33269 FUN_032133 427 165 425 467 600 ptg000023l:29105077-29121376 Q7LHG5 2.34e-79 Transposon Ty3-I Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-2 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p52 (IN); Integrase p49 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 33270 FUN_032132 1703 1022 1408 2332 1896 ptg000023l:29089531-29101416 Q94515 2.39e-129 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 33271 FUN_032132 1703 1022 1408 2332 1896 ptg000023l:29089531-29101416 Q94515 1.61e-128 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Degenerative spermatocyte homolog 1) (DES-1) (Dihydroceramide desaturase-1) Drosophila melanogaster (Fruit fly) ceramide biosynthetic process [GO:0046513]; negative regulation of lipophagy [GO:1904503]; spermatogenesis [GO:0007283]; spindle assembly involved in male meiosis [GO:0007053] GO:0005739; GO:0005770; GO:0005783; GO:0005789; GO:0005886; GO:0007053; GO:0007283; GO:0016006; GO:0042284; GO:0046513; GO:0070938; GO:1904503 33272 FUN_032135 7 0 0 19 13 NA NA NA NA NA NA NA 33273 FUN_032134 18 0 25 28 34 NA NA NA NA NA NA NA 33274 FUN_032137 776 812 596 854 782 NA NA NA NA NA NA NA 33275 FUN_032136 2879 2681 1821 4304 5561 ptg000023l:29137382-29147036 Q5EAB6 9.6e-24 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 33276 FUN_032136 2879 2681 1821 4304 5561 ptg000023l:29137382-29147036 Q5EAB6 1.27e-21 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) Bos taurus (Bovine) O-glycan processing [GO:0016266]; protein O-linked glycosylation [GO:0006493] GO:0000139; GO:0006493; GO:0008375; GO:0016020; GO:0016266; GO:0030145 33277 FUN_032139 2700 1198 1115 2750 2427 NA NA NA NA NA NA NA 33278 FUN_005212 0 40 0 16 13 NA NA NA NA NA NA NA 33279 FUN_042030 956 705 438 1055 749 ptg000035l:9930646-9932144 Q8IN35 4.51e-31 Neuropeptide SIFamide receptor Drosophila melanogaster (Fruit fly) determination of adult lifespan [GO:0008340]; G protein-coupled receptor signaling pathway [GO:0007186]; mating behavior, sex discrimination [GO:0048047]; neuropeptide signaling pathway [GO:0007218] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:0007218; GO:0008188; GO:0008340; GO:0008528; GO:0016020; GO:0042277; GO:0048047 33280 FUN_006098 11 37 20 0 4 NA NA NA NA NA NA NA 33281 FUN_004146 10 7 11 32 22 NA NA NA NA NA NA NA 33282 FUN_043928 0 6 1 0 0 NA NA NA NA NA NA NA 33283 FUN_000185 6946 5286 4456 5580 6620 ntLink_6:68889-102137 P04323 1.17e-65 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 33284 FUN_000184 15622 9797 5833 10065 7715 NA NA NA NA NA NA NA 33285 FUN_000186 161 141 80 149 431 NA NA NA NA NA NA NA 33286 FUN_000183 0 0 0 0 14 NA NA NA NA NA NA NA 33287 FUN_000182 125 27 86 0 43 NA NA NA NA NA NA NA 33288 FUN_000189 10593 12572 5155 7185 4474 NA NA NA NA NA NA NA 33289 FUN_015893 37 28 6 3 699 NA NA NA NA NA NA NA 33290 FUN_026797 0 0 0 0 44 NA NA NA NA NA NA NA 33291 FUN_015892 0 0 0 16 0 NA NA NA NA NA NA NA 33292 FUN_008408 3715 2656 1342 1977 1605 ptg000002l:11204578-11214238 O15270 1.05e-23 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Homo sapiens (Human) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:1904504 33293 FUN_008408 3715 2656 1342 1977 1605 ptg000002l:11204578-11214238 O15270 1.31e-21 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Homo sapiens (Human) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingolipid biosynthetic process [GO:0030148]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005789; GO:0006686; GO:0017059; GO:0030148; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:1904504 33294 FUN_008409 44 150 24 44 81 ptg000002l:11216852-11219373 Q14314 2.32e-34 Fibroleukin (Fibrinogen-like protein 2) (pT49) Homo sapiens (Human) negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005576; GO:0005577; GO:0005615; GO:0043381; GO:0050687; GO:0062023; GO:0070062; GO:1904813 33295 FUN_008400 3905 4607 2540 7461 2808 ptg000002l:11149264-11152982 Q3TBV4 4.39e-24 NA NA NA NA 33296 FUN_008401 51 69 35 165 101 ptg000002l:11155089-11157300 Q9UBT6 0 DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to UV [GO:0034644]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; error-prone translesion synthesis [GO:0042276]; nucleotide-excision repair, DNA gap filling [GO:0006297] GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0006260; GO:0006281; GO:0006297; GO:0006974; GO:0016604; GO:0034644; GO:0042276; GO:0046872 33297 FUN_008402 708 469 304 687 613 ptg000002l:11157651-11165427 P0A962 1.22e-24 L-asparaginase 1 (EC 3.5.1.1) (L-asparaginase I) (L-ASNase I) (L-asparagine amidohydrolase I) Escherichia coli (strain K12) asparagine catabolic process via L-aspartate [GO:0033345]; protein homotetramerization [GO:0051289] GO:0004067; GO:0005737; GO:0005829; GO:0033345; GO:0042802; GO:0051289 33298 FUN_008403 1624 1057 645 1242 1383 NA NA NA NA NA NA NA 33299 FUN_008404 62 26 95 84 13 NA NA NA NA NA NA NA 33300 FUN_008405 193 98 198 357 179 NA NA NA NA NA NA NA 33301 FUN_008406 166 254 134 332 152 ptg000002l:11192146-11196762 O54694 3.24e-22 Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) adipose tissue development [GO:0060612]; ceramide biosynthetic process [GO:0046513]; positive regulation of lipophagy [GO:1904504]; sphinganine biosynthetic process [GO:0046511]; sphingomyelin biosynthetic process [GO:0006686]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005789; GO:0006686; GO:0017059; GO:0030170; GO:0046511; GO:0046512; GO:0046513; GO:0060612; GO:1904504 33302 FUN_008407 37 74 51 170 55 ptg000002l:11197252-11202054 Q9NUV7 2.75e-24 Serine palmitoyltransferase 3 (EC 2.3.1.50) (Long chain base biosynthesis protein 2b) (LCB2b) (Long chain base biosynthesis protein 3) (LCB 3) (Serine-palmitoyl-CoA transferase 3) (SPT 3) Homo sapiens (Human) ceramide biosynthetic process [GO:0046513]; sphingoid biosynthetic process [GO:0046520]; sphingolipid biosynthetic process [GO:0030148]; sphingosine biosynthetic process [GO:0046512] GO:0004758; GO:0005789; GO:0017059; GO:0030148; GO:0030170; GO:0046512; GO:0046513; GO:0046520 33303 FUN_015899 37 0 0 2 0 NA NA NA NA NA NA NA 33304 FUN_041409 1486 1613 1060 2178 1717 NA NA NA NA NA NA NA 33305 FUN_041408 3355 1763 1425 2878 2927 NA NA NA NA NA NA NA 33306 FUN_000239 21830 24474 12433 13406 28944 NA NA NA NA NA NA NA 33307 FUN_000238 841 816 514 655 533 NA NA NA NA NA NA NA 33308 FUN_013923 0 11 15 0 59 NA NA NA NA NA NA NA 33309 FUN_000236 642 362 326 654 508 NA NA NA NA NA NA NA 33310 FUN_000235 0 0 23 8 2 NA NA NA NA NA NA NA 33311 FUN_000234 30 0 62 59 0 NA NA NA NA NA NA NA 33312 FUN_041405 374 279 140 231 270 NA NA NA NA NA NA NA 33313 FUN_041404 3337 2677 890 2299 626 NA NA NA NA NA NA NA 33314 FUN_017921 1352 905 652 991 1283 ptg000012l:1896567-1904938 Q9Y253 6.04e-22 DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein) Homo sapiens (Human) cellular response to UV-C [GO:0071494]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; DNA synthesis involved in DNA repair [GO:0000731]; error-free translesion synthesis [GO:0070987]; error-prone translesion synthesis [GO:0042276]; pyrimidine dimer repair [GO:0006290]; regulation of DNA repair [GO:0006282]; response to radiation [GO:0009314]; response to UV-C [GO:0010225] GO:0000731; GO:0003684; GO:0003887; GO:0005634; GO:0005654; GO:0005657; GO:0005829; GO:0006260; GO:0006281; GO:0006282; GO:0006290; GO:0009314; GO:0010225; GO:0035861; GO:0042276; GO:0046872; GO:0070987; GO:0071494 33315 FUN_008169 29 19 0 0 15 NA NA NA NA NA NA NA 33316 FUN_042976 547 468 67 538 921 NA NA NA NA NA NA NA 33317 FUN_026792 0 0 0 14 6 NA NA NA NA NA NA NA 33318 FUN_033778 4666 3175 2974 3405 3181 ptg000024l:1282099-1292151 Q91YA9 1.21e-25 Basic helix-loop-helix ARNT-like protein 1 (Aryl hydrocarbon receptor nuclear translocator-like protein 1) (Basic-helix-loop-helix-PAS protein MOP3) (Brain and muscle ARNT-like 1) Nannospalax galili (Northern Israeli blind subterranean mole rat) (Spalax galili) circadian regulation of gene expression [GO:0032922]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of TOR signaling [GO:0032007]; oxidative stress-induced premature senescence [GO:0090403]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of circadian rhythm [GO:0042753]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein acetylation [GO:1901985]; positive regulation of skeletal muscle cell differentiation [GO:2001016]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; regulation of cell cycle [GO:0051726]; regulation of cellular senescence [GO:2000772]; regulation of DNA-templated transcription [GO:0006355]; regulation of hair cycle [GO:0042634]; regulation of insulin secretion [GO:0050796]; regulation of neurogenesis [GO:0050767]; regulation of type B pancreatic cell development [GO:2000074]; response to redox state [GO:0051775]; spermatogenesis [GO:0007283] GO:0000978; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0007283; GO:0016605; GO:0032007; GO:0032922; GO:0033391; GO:0042634; GO:0042753; GO:0043161; GO:0045599; GO:0045893; GO:0046983; GO:0050767; GO:0050796; GO:0051726; GO:0051775; GO:0070888; GO:0090263; GO:0090403; GO:1901985; GO:2000074; GO:2000772; GO:2001016 33319 FUN_033779 18989 7277 6589 14969 7838 NA NA NA NA NA NA NA 33320 FUN_018457 2 0 0 0 42 NA NA NA NA NA NA NA 33321 FUN_033770 270 492 380 191 241 NA NA NA NA NA NA NA 33322 FUN_033771 303 66 147 208 183 NA NA NA NA NA NA NA 33323 FUN_033772 1723 816 853 1342 1734 ptg000024l:1206164-1209595 Q8TF71 1.32e-22 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Homo sapiens (Human) amino acid transport [GO:0006865]; aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0006865; GO:0015171; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 33324 FUN_033772 1723 816 853 1342 1734 ptg000024l:1206164-1209595 Q8TF71 1.32e-22 Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1) Homo sapiens (Human) amino acid transport [GO:0006865]; aromatic amino acid transport [GO:0015801]; thyroid hormone generation [GO:0006590]; thyroid hormone transport [GO:0070327]; thyroid-stimulating hormone secretion [GO:0070460] GO:0005302; GO:0005886; GO:0006590; GO:0006865; GO:0015171; GO:0015173; GO:0015192; GO:0015196; GO:0015349; GO:0015801; GO:0016020; GO:0016323; GO:0030054; GO:0043231; GO:0070327; GO:0070460 33325 FUN_033773 3198 2167 1526 3224 2324 ptg000024l:1214161-1238678 B9EJ86 5.05e-25 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 33326 FUN_033773 3198 2167 1526 3224 2324 ptg000024l:1214161-1238678 B9EJ86 2.13e-21 Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8) Mus musculus (Mouse) activation of protein kinase B activity [GO:0032148]; fat cell differentiation [GO:0045444]; negative regulation of cell migration [GO:0030336]; negative regulation of sequestering of triglyceride [GO:0010891]; phospholipid transport [GO:0015914]; positive regulation of glucose import [GO:0046326]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of protein kinase B signaling [GO:0051897]; protein localization to nuclear pore [GO:0090204] GO:0001786; GO:0005783; GO:0005789; GO:0005829; GO:0010891; GO:0015248; GO:0015485; GO:0015914; GO:0016020; GO:0030336; GO:0031965; GO:0032148; GO:0032541; GO:0032934; GO:0043231; GO:0045444; GO:0046326; GO:0046628; GO:0051897; GO:0070273; GO:0090204; GO:0140343 33327 FUN_033774 128 384 99 167 286 NA NA NA NA NA NA NA 33328 FUN_018454 3 1 4 3 6 NA NA NA NA NA NA NA 33329 FUN_033776 37473 54418 26972 36705 32380 NA NA NA NA NA NA NA 33330 FUN_037021 63 65 25 41 0 NA NA NA NA NA NA NA 33331 FUN_018455 948 349 125 549 903 NA NA NA NA NA NA NA 33332 FUN_018452 0 0 26 66 0 NA NA NA NA NA NA NA 33333 FUN_034024 36 49 37 34 49 NA NA NA NA NA NA NA 33334 FUN_034026 883 816 517 937 1004 NA NA NA NA NA NA NA 33335 FUN_003769 0 0 12 0 0 NA NA NA NA NA NA NA 33336 FUN_003764 33 0 4 8 173 NA NA NA NA NA NA NA 33337 FUN_003765 0 0 0 0 8 NA NA NA NA NA NA NA 33338 FUN_003760 1 0 34 0 56 NA NA NA NA NA NA NA 33339 FUN_003762 0 0 0 7 7 NA NA NA NA NA NA NA 33340 FUN_003763 0 0 14 0 0 NA NA NA NA NA NA NA 33341 FUN_035630 28 4 12 22 0 NA NA NA NA NA NA NA 33342 FUN_012323 504 428 191 14 0 NA NA NA NA NA NA NA 33343 FUN_012324 528 418 360 766 941 NA NA NA NA NA NA NA 33344 FUN_012328 14 0 0 0 0 ptg000008l:7918215-7920960 Q6DH69 8.63e-57 Fatty-acid amide hydrolase 2-A (EC 3.5.1.99) Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042] GO:0016020; GO:0016042; GO:0017064 33345 FUN_012328 14 0 0 0 0 ptg000008l:7918215-7920960 Q6DH69 9.18e-46 Fatty-acid amide hydrolase 2-A (EC 3.5.1.99) Danio rerio (Zebrafish) (Brachydanio rerio) lipid catabolic process [GO:0016042] GO:0016020; GO:0016042; GO:0017064 33346 FUN_012329 279 66 90 127 93 ptg000008l:7926529-7930091 Q6GMR7 4.07e-76 Fatty-acid amide hydrolase 2 (EC 3.5.1.99) (Amidase domain-containing protein) (Anandamide amidohydrolase 2) (Oleamide hydrolase 2) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042] GO:0005811; GO:0016020; GO:0016042; GO:0017064; GO:0019369 33347 FUN_012329 279 66 90 127 93 ptg000008l:7926529-7930091 Q6GMR7 2.18e-43 Fatty-acid amide hydrolase 2 (EC 3.5.1.99) (Amidase domain-containing protein) (Anandamide amidohydrolase 2) (Oleamide hydrolase 2) Homo sapiens (Human) arachidonic acid metabolic process [GO:0019369]; lipid catabolic process [GO:0016042] GO:0005811; GO:0016020; GO:0016042; GO:0017064; GO:0019369 33348 FUN_028213 0 0 0 0 10 NA NA NA NA NA NA NA 33349 FUN_010783 1811 753 617 1170 1253 NA NA NA NA NA NA NA 33350 FUN_010780 3440 2502 1010 2014 1101 NA NA NA NA NA NA NA 33351 FUN_010781 1355 524 299 819 547 NA NA NA NA NA NA NA 33352 FUN_028217 4 0 0 0 11 NA NA NA NA NA NA NA 33353 FUN_010787 5587 3369 2678 4278 1426 ptg000007l:2773910-2781375 A0A1Y9G8H0 1.56e-26 NA NA NA NA 33354 FUN_010784 1116 1250 914 772 732 NA NA NA NA NA NA NA 33355 FUN_010785 398 496 393 338 369 NA NA NA NA NA NA NA 33356 FUN_010788 0 3 0 0 7 NA NA NA NA NA NA NA 33357 FUN_010789 11659 8218 6425 8738 5427 ptg000007l:2793663-2798879 B3A0Q8 7.31e-26 Peroxidase-like protein 3 Lottia gigantea (Giant owl limpet) response to oxidative stress [GO:0006979] GO:0004601; GO:0005576; GO:0006979; GO:0020037 33358 FUN_034209 701 760 362 843 849 NA NA NA NA NA NA NA 33359 FUN_034208 266 130 239 212 191 NA NA NA NA NA NA NA 33360 FUN_034201 135 103 49 113 76 NA NA NA NA NA NA NA 33361 FUN_034200 650 595 344 571 224 NA NA NA NA NA NA NA 33362 FUN_034203 5707 6302 4470 9994 8669 NA NA NA NA NA NA NA 33363 FUN_034202 3236 973 1176 1714 1196 NA NA NA NA NA NA NA 33364 FUN_034205 25 25 27 26 144 NA NA NA NA NA NA NA 33365 FUN_034204 451 338 67 235 263 NA NA NA NA NA NA NA 33366 FUN_034206 0 0 0 0 22 NA NA NA NA NA NA NA 33367 FUN_028402 22 0 0 0 0 NA NA NA NA NA NA NA 33368 FUN_023452 72 53 86 315 54 NA NA NA NA NA NA NA 33369 FUN_011789 24 0 0 0 0 NA NA NA NA NA NA NA 33370 FUN_011788 121 44 54 111 51 NA NA NA NA NA NA NA 33371 FUN_028404 0 207 63 17 0 NA NA NA NA NA NA NA 33372 FUN_011781 1235 304 181 1057 396 ptg000008l:1393096-1400871 A7S2N8 4.76e-34 E3 UFM1-protein ligase 1 homolog (EC 2.3.2.-) (E3 UFM1-protein transferase 1 homolog) Nematostella vectensis (Starlet sea anemone) protein K69-linked ufmylation [GO:1990592]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; response to endoplasmic reticulum stress [GO:0034976] GO:0005789; GO:0032434; GO:0034976; GO:0061666; GO:0071568; GO:1990592 33373 FUN_011780 363 369 237 270 461 ptg000008l:1388966-1390659 A7S2N8 7.89e-23 E3 UFM1-protein ligase 1 homolog (EC 2.3.2.-) (E3 UFM1-protein transferase 1 homolog) Nematostella vectensis (Starlet sea anemone) protein K69-linked ufmylation [GO:1990592]; regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032434]; response to endoplasmic reticulum stress [GO:0034976] GO:0005789; GO:0032434; GO:0034976; GO:0061666; GO:0071568; GO:1990592 33374 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 1.25e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33375 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 7.85e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33376 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 6.98e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33377 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 2.13e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33378 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 7.39e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33379 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 7.87e-144 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33380 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 5.54e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33381 FUN_011783 56 11 62 18 487 ptg000008l:1414926-1421940 Q96AY4 2.29e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33382 FUN_011782 412 267 131 227 467 NA NA NA NA NA NA NA 33383 FUN_011785 6 68 39 129 4 NA NA NA NA NA NA NA 33384 FUN_011784 0 0 0 0 24 NA NA NA NA NA NA NA 33385 FUN_011787 0 0 0 0 43 NA NA NA NA NA NA NA 33386 FUN_011786 0 0 0 0 18 NA NA NA NA NA NA NA 33387 FUN_014441 1759 1779 802 979 598 NA NA NA NA NA NA NA 33388 FUN_013492 0 53 0 0 0 NA NA NA NA NA NA NA 33389 FUN_013491 0 3 0 0 8 NA NA NA NA NA NA NA 33390 FUN_014442 2041 1926 1562 2199 1901 NA NA NA NA NA NA NA 33391 FUN_014447 21398 23221 14857 18083 10848 NA NA NA NA NA NA NA 33392 FUN_014449 3047 2268 1283 2066 1770 NA NA NA NA NA NA NA 33393 FUN_014448 1849 1659 820 1280 1402 NA NA NA NA NA NA NA 33394 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 1.03e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33395 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 4.96e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33396 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 1.79e-68 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33397 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 8.86e-66 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33398 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 7.73e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33399 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 1e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33400 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 8.69e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33401 FUN_013499 706 1440 593 1985 787 ptg000008l:23346045-23360718 Q7RTR2 4.84e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33402 FUN_043113 156 162 121 365 284 ptg000047l:4279106-4280162 Q99963 3.02e-85 Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3) Homo sapiens (Human) central nervous system development [GO:0007417]; negative regulation of clathrin-dependent endocytosis [GO:1900186]; positive regulation of neuron differentiation [GO:0045666]; signal transduction [GO:0007165]; synaptic vesicle uncoating [GO:0016191] GO:0001669; GO:0005737; GO:0007165; GO:0007417; GO:0008022; GO:0008289; GO:0016191; GO:0031901; GO:0042802; GO:0045666; GO:0098793; GO:0098845; GO:0098978; GO:0099092; GO:1900186 33403 FUN_043112 1066 441 371 855 844 NA NA NA NA NA NA NA 33404 FUN_043111 74884 90961 33997 72595 38405 NA NA NA NA NA NA NA 33405 FUN_043110 95 73 77 114 113 ptg000047l:4244630-4246133 O73853 6.12e-101 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Ictalurus punctatus (Channel catfish) (Silurus punctatus) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 33406 FUN_043117 80 92 79 132 69 NA NA NA NA NA NA NA 33407 FUN_043116 3355 1344 1756 3805 1964 ptg000047l:4304860-4313610 O77633 1.2e-53 Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) Sus scrofa (Pig) adherens junction organization [GO:0034332]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] GO:0000139; GO:0001701; GO:0004175; GO:0004222; GO:0005634; GO:0005798; GO:0005886; GO:0005912; GO:0006468; GO:0006509; GO:0007162; GO:0007219; GO:0008284; GO:0008593; GO:0009986; GO:0010629; GO:0010820; GO:0014069; GO:0017124; GO:0019901; GO:0030136; GO:0030307; GO:0030424; GO:0030425; GO:0034332; GO:0034612; GO:0038004; GO:0042117; GO:0042803; GO:0046872; GO:0046930; GO:0046931; GO:0051089; GO:0070573; GO:0090102; GO:0097038; GO:0097060; GO:0097197; GO:0098696; GO:0098978; GO:0099173; GO:0099175; GO:0140249; GO:1901342; GO:1901998; GO:1902945 33408 FUN_043116 3355 1344 1756 3805 1964 ptg000047l:4304860-4313610 O77633 8.87e-35 Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c) Sus scrofa (Pig) adherens junction organization [GO:0034332]; cochlea development [GO:0090102]; constitutive protein ectodomain proteolysis [GO:0051089]; epidermal growth factor receptor ligand maturation [GO:0038004]; in utero embryonic development [GO:0001701]; membrane protein ectodomain proteolysis [GO:0006509]; monocyte activation [GO:0042117]; negative regulation of cell adhesion [GO:0007162]; negative regulation of gene expression [GO:0010629]; Notch signaling pathway [GO:0007219]; pore complex assembly [GO:0046931]; positive regulation of cell growth [GO:0030307]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of T cell chemotaxis [GO:0010820]; postsynapse organization [GO:0099173]; protein catabolic process at postsynapse [GO:0140249]; protein phosphorylation [GO:0006468]; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane [GO:0098696]; regulation of Notch signaling pathway [GO:0008593]; regulation of postsynapse organization [GO:0099175]; regulation of vasculature development [GO:1901342]; response to tumor necrosis factor [GO:0034612]; toxin transport [GO:1901998] GO:0000139; GO:0001701; GO:0004175; GO:0004222; GO:0005634; GO:0005798; GO:0005886; GO:0005912; GO:0006468; GO:0006509; GO:0007162; GO:0007219; GO:0008284; GO:0008593; GO:0009986; GO:0010629; GO:0010820; GO:0014069; GO:0017124; GO:0019901; GO:0030136; GO:0030307; GO:0030424; GO:0030425; GO:0034332; GO:0034612; GO:0038004; GO:0042117; GO:0042803; GO:0046872; GO:0046930; GO:0046931; GO:0051089; GO:0070573; GO:0090102; GO:0097038; GO:0097060; GO:0097197; GO:0098696; GO:0098978; GO:0099173; GO:0099175; GO:0140249; GO:1901342; GO:1901998; GO:1902945 33409 FUN_043115 1963 1070 774 1268 1324 NA NA NA NA NA NA NA 33410 FUN_025116 717 1648 830 606 1140 ptg000018l:14048924-14081836 A0A1C9U5X5 2e-28 Reticuline N-methyltransferase (RNMT) (EC 2.1.1.337) (N-methyltransferase 3) Papaver somniferum (Opium poppy) methylation [GO:0032259] GO:0032259; GO:0102964 33411 FUN_000952 0 7 0 0 0 NA NA NA NA NA NA NA 33412 FUN_000953 473 534 289 629 321 NA NA NA NA NA NA NA 33413 FUN_011439 0 0 0 0 23 NA NA NA NA NA NA NA 33414 FUN_043118 45498 32307 25116 35807 15600 NA NA NA NA NA NA NA 33415 FUN_000956 314 294 278 623 389 NA NA NA NA NA NA NA 33416 FUN_000957 259 321 66 385 98 NA NA NA NA NA NA NA 33417 FUN_000954 311 138 213 62 134 NA NA NA NA NA NA NA 33418 FUN_000955 140 154 114 122 94 NA NA NA NA NA NA NA 33419 FUN_022325 2068 1795 788 1704 1583 NA NA NA NA NA NA NA 33420 FUN_025112 23 0 25 0 7 NA NA NA NA NA NA NA 33421 FUN_013145 1187 623 564 959 1079 ptg000008l:20022640-20046411 Q02361 2.73e-24 Fork head domain-containing protein FD3 Drosophila melanogaster (Fruit fly) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0030154 33422 FUN_013144 91 115 81 102 113 NA NA NA NA NA NA NA 33423 FUN_013147 7 0 4 21 46 ptg000008l:20066067-20068884 Q02361 3.65e-25 Fork head domain-containing protein FD3 Drosophila melanogaster (Fruit fly) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0030154 33424 FUN_013146 2684 1440 884 2449 1335 NA NA NA NA NA NA NA 33425 FUN_013140 209 127 42 64 285 NA NA NA NA NA NA NA 33426 FUN_013143 249 183 137 119 48 NA NA NA NA NA NA NA 33427 FUN_025110 0 0 12 0 0 NA NA NA NA NA NA NA 33428 FUN_013149 271 126 361 241 365 NA NA NA NA NA NA NA 33429 FUN_013148 780 532 1114 780 463 ptg000008l:20076101-20096147 P15043 1.14e-34 ATP-dependent DNA helicase RecQ (EC 3.6.4.12) Escherichia coli (strain K12) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; DNA replication [GO:0006260]; SOS response [GO:0009432] GO:0003677; GO:0003678; GO:0005524; GO:0005694; GO:0005737; GO:0006260; GO:0006281; GO:0006310; GO:0006974; GO:0008094; GO:0008270; GO:0009378; GO:0009432; GO:0016887; GO:0017116; GO:0017117; GO:0030894; GO:0032508; GO:0043138; GO:0043590; GO:0046914 33430 FUN_009721 84 0 23 0 0 NA NA NA NA NA NA NA 33431 FUN_009727 96 22 0 22 24 ptg000004l:10824187-10827946 Q96AY4 5.82e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33432 FUN_009727 96 22 0 22 24 ptg000004l:10824187-10827946 Q96AY4 5.63e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33433 FUN_009727 96 22 0 22 24 ptg000004l:10824187-10827946 Q96AY4 7.06e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33434 FUN_009727 96 22 0 22 24 ptg000004l:10824187-10827946 Q96AY4 2.79e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33435 FUN_009727 96 22 0 22 24 ptg000004l:10824187-10827946 Q96AY4 4.75e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33436 FUN_009728 42 67 52 144 64 NA NA NA NA NA NA NA 33437 FUN_029628 67 70 91 0 41 NA NA NA NA NA NA NA 33438 FUN_029620 691 301 451 201 639 NA NA NA NA NA NA NA 33439 FUN_029623 38 1 55 13 23 NA NA NA NA NA NA NA 33440 FUN_029622 277 176 131 149 231 ptg000023l:3822790-3877970 P79729 2.83e-25 Desert hedgehog protein (DHH) Danio rerio (Zebrafish) (Brachydanio rerio) cell fate specification [GO:0001708]; cell-cell signaling [GO:0007267]; proteolysis [GO:0006508]; regulation of gene expression [GO:0010468]; smoothened signaling pathway [GO:0007224] GO:0001708; GO:0005113; GO:0005509; GO:0005615; GO:0005886; GO:0006508; GO:0007224; GO:0007267; GO:0008233; GO:0010468 33441 FUN_029625 449 350 363 2 426 NA NA NA NA NA NA NA 33442 FUN_029624 1087 499 410 386 629 NA NA NA NA NA NA NA 33443 FUN_026512 643 868 370 504 424 NA NA NA NA NA NA NA 33444 FUN_026513 1065 620 566 1009 869 NA NA NA NA NA NA NA 33445 FUN_026511 1374 1201 740 1512 1308 NA NA NA NA NA NA NA 33446 FUN_026514 133 252 34 366 181 NA NA NA NA NA NA NA 33447 FUN_026515 214 20 0 125 106 NA NA NA NA NA NA NA 33448 FUN_026518 5 0 0 14 22 NA NA NA NA NA NA NA 33449 FUN_015796 25 11 0 2 0 NA NA NA NA NA NA NA 33450 FUN_015797 93 0 137 76 456 NA NA NA NA NA NA NA 33451 FUN_015794 753 427 177 619 250 ptg000009l:16014328-16019892 Q9NBX4 5.39e-32 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 33452 FUN_015795 0 0 0 4 10 NA NA NA NA NA NA NA 33453 FUN_015792 75 57 22 37 39 NA NA NA NA NA NA NA 33454 FUN_042360 392 0 0 0 0 NA NA NA NA NA NA NA 33455 FUN_015428 351 262 366 440 127 NA NA NA NA NA NA NA 33456 FUN_015429 1044 809 426 997 1136 ptg000009l:10043602-10076001 Q1RLX4 8.9e-25 Trafficking protein particle complex subunit 11 (Protein foie gras) Danio rerio (Zebrafish) (Brachydanio rerio) Golgi organization [GO:0007030]; lipid homeostasis [GO:0055088]; liver development [GO:0001889]; protein N-linked glycosylation [GO:0006487]; protein secretion [GO:0009306]; regulation of response to endoplasmic reticulum stress [GO:1905897]; retina development in camera-type eye [GO:0060041]; vesicle-mediated transport [GO:0016192] GO:0001889; GO:0005794; GO:0006487; GO:0007030; GO:0009306; GO:0016192; GO:0055088; GO:0060041; GO:1905897 33457 FUN_015420 1845 30065 731 3027 25633 NA NA NA NA NA NA NA 33458 FUN_015423 1176 842 579 588 453 NA NA NA NA NA NA NA 33459 FUN_015424 570 529 482 415 685 ptg000009l:9990835-10005903 E7FAM5 1.82e-65 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 33460 FUN_015425 331 139 240 188 241 NA NA NA NA NA NA NA 33461 FUN_015426 60 22 58 44 25 NA NA NA NA NA NA NA 33462 FUN_015427 30 33 39 38 58 ptg000009l:10022365-10026698 D3ZVM4 5e-75 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Rattus norvegicus (Rat) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0016567; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 33463 FUN_008893 3 26 19 69 20 NA NA NA NA NA NA NA 33464 FUN_008892 755 642 479 563 569 NA NA NA NA NA NA NA 33465 FUN_008891 391 119 97 185 279 ptg000004l:326722-328362 P35406 2.99e-34 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 33466 FUN_008890 4428 4417 3149 5706 2577 NA NA NA NA NA NA NA 33467 FUN_008897 313 235 112 179 114 NA NA NA NA NA NA NA 33468 FUN_008895 387 183 162 456 259 NA NA NA NA NA NA NA 33469 FUN_008894 0 0 0 14 0 NA NA NA NA NA NA NA 33470 FUN_008899 369 702 116 650 704 NA NA NA NA NA NA NA 33471 FUN_008898 2048 875 1083 1762 1290 NA NA NA NA NA NA NA 33472 FUN_032008 46 36 8 192 207 NA NA NA NA NA NA NA 33473 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 1.39e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33474 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 1.63e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33475 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 9.85e-86 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33476 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 1.84e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33477 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 1.91e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33478 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 2.93e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33479 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 1.03e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33480 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 4.23e-54 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33481 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 1.4e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33482 FUN_018776 192 151 130 212 760 ptg000012l:13321667-13332032 Q96AY4 2.11e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33483 FUN_018775 498 19 227 227 742 NA NA NA NA NA NA NA 33484 FUN_032006 157 244 250 279 224 NA NA NA NA NA NA NA 33485 FUN_018773 160 131 66 50 1281 NA NA NA NA NA NA NA 33486 FUN_018771 0 0 36 0 0 NA NA NA NA NA NA NA 33487 FUN_018770 1 10 48 0 15 NA NA NA NA NA NA NA 33488 FUN_024915 7 10 0 0 20 NA NA NA NA NA NA NA 33489 FUN_024916 36 838 0 0 306 NA NA NA NA NA NA NA 33490 FUN_024910 309 234 179 448 94 NA NA NA NA NA NA NA 33491 FUN_024911 34 0 0 0 159 NA NA NA NA NA NA NA 33492 FUN_024912 8 32 32 9 12 ptg000018l:12574089-12574584 P32320 1.81e-42 Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase) Homo sapiens (Human) cell surface receptor signaling pathway [GO:0007166]; cellular response to external biotic stimulus [GO:0071217]; cytidine deamination [GO:0009972]; cytosine metabolic process [GO:0019858]; negative regulation of cell growth [GO:0030308]; negative regulation of nucleotide metabolic process [GO:0045980]; pyrimidine-containing compound salvage [GO:0008655]; response to cycloheximide [GO:0046898]; UMP salvage [GO:0044206] GO:0001882; GO:0004126; GO:0005576; GO:0005829; GO:0007166; GO:0008270; GO:0008655; GO:0009972; GO:0019858; GO:0030308; GO:0034774; GO:0042802; GO:0042803; GO:0044206; GO:0045980; GO:0046898; GO:0047844; GO:0071217; GO:1904724; GO:1904813 33493 FUN_024918 0 0 0 0 16 NA NA NA NA NA NA NA 33494 FUN_024919 4 0 0 0 13 NA NA NA NA NA NA NA 33495 FUN_038274 1643 1259 705 1282 939 NA NA NA NA NA NA NA 33496 FUN_038275 4606 4189 2123 3301 1896 NA NA NA NA NA NA NA 33497 FUN_038276 2651 1391 1184 2476 1616 NA NA NA NA NA NA NA 33498 FUN_038277 6642 3482 2440 9302 14690 ptg000027l:5103305-5214011 Q29116 2.57e-31 Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (P230) (Tenascin-C) (TN-C) Sus scrofa (Pig) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0062023 33499 FUN_038277 6642 3482 2440 9302 14690 ptg000027l:5103305-5214011 Q29116 9.07e-26 Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (P230) (Tenascin-C) (TN-C) Sus scrofa (Pig) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0062023 33500 FUN_038277 6642 3482 2440 9302 14690 ptg000027l:5103305-5214011 Q29116 1.27e-22 Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (P230) (Tenascin-C) (TN-C) Sus scrofa (Pig) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0062023 33501 FUN_038277 6642 3482 2440 9302 14690 ptg000027l:5103305-5214011 Q29116 5.61e-22 Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (P230) (Tenascin-C) (TN-C) Sus scrofa (Pig) cell adhesion [GO:0007155] GO:0005102; GO:0005615; GO:0007155; GO:0062023 33502 FUN_038270 541 362 621 628 841 NA NA NA NA NA NA NA 33503 FUN_038271 1951 1585 1009 2142 1281 ptg000027l:4965481-5005667 Q4GZT3 5.73e-41 Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Transient receptor potential cation channel subfamily P member 2) Bos taurus (Bovine) calcium ion transmembrane transport [GO:0070588]; cell-cell signaling by wnt [GO:0198738]; cellular response to calcium ion [GO:0071277]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein heterotetramerization [GO:0051290]; protein tetramerization [GO:0051262]; regulation of ion transmembrane transport [GO:0034765]; release of sequestered calcium ion into cytosol [GO:0051209]; Wnt signaling pathway [GO:0016055] GO:0002133; GO:0005102; GO:0005245; GO:0005248; GO:0005261; GO:0005262; GO:0005267; GO:0005509; GO:0005783; GO:0005789; GO:0005794; GO:0005886; GO:0005929; GO:0015271; GO:0016020; GO:0016055; GO:0016323; GO:0030659; GO:0034703; GO:0034765; GO:0050982; GO:0051209; GO:0051262; GO:0051290; GO:0051371; GO:0060170; GO:0070588; GO:0071277; GO:0071805; GO:0098662; GO:0198738 33504 FUN_038272 501 226 222 189 589 NA NA NA NA NA NA NA 33505 FUN_038273 7934 10610 2402 6195 2264 NA NA NA NA NA NA NA 33506 FUN_038278 0 0 0 8 2 NA NA NA NA NA NA NA 33507 FUN_038279 1857 1347 1190 2384 1411 NA NA NA NA NA NA NA 33508 FUN_025355 1483 521 263 4138 246 ptg000019l:1790860-1807211 P21328 9.8e-21 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 33509 FUN_025354 13 0 0 18 0 ptg000019l:1779938-1781632 P10978 3.19e-33 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 33510 FUN_025354 13 0 0 18 0 ptg000019l:1779938-1781632 P10978 3.19e-33 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 33511 FUN_025354 13 0 0 18 0 ptg000019l:1779938-1781632 P10978 3.19e-33 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 33512 FUN_025356 104 37 0 48 22 NA NA NA NA NA NA NA 33513 FUN_025351 4764 3112 2244 4860 2876 NA NA NA NA NA NA NA 33514 FUN_025350 1077 1506 697 1946 1324 NA NA NA NA NA NA NA 33515 FUN_025353 255 97 10 49 24 NA NA NA NA NA NA NA 33516 FUN_025352 0 0 5 0 38 NA NA NA NA NA NA NA 33517 FUN_025359 3135 1561 327 1086 123 NA NA NA NA NA NA NA 33518 FUN_025358 51 0 23 41 0 NA NA NA NA NA NA NA 33519 FUN_033834 693 341 280 678 462 ptg000024l:1749200-1753395 Q6L9W6 1.58e-22 Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2) Homo sapiens (Human) NA GO:0005794; GO:0008376; GO:0032580; GO:0033842; GO:0043231 33520 FUN_019424 7 101 282 119 234 NA NA NA NA NA NA NA 33521 FUN_019426 0 0 48 0 36 NA NA NA NA NA NA NA 33522 FUN_044335 2 0 0 0 7 NA NA NA NA NA NA NA 33523 FUN_030064 664 54 138 375 348 ptg000023l:9008068-9028389 Q99315 5.8e-40 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 33524 FUN_030064 664 54 138 375 348 ptg000023l:9008068-9028389 Q99315 5.8e-40 Transposon Ty3-G Gag-Pol polyprotein (Gag3-Pol3) (Transposon Ty3-1 TYA-TYB polyprotein) [Cleaved into: Capsid protein (CA) (p24); Spacer peptide p3; Nucleocapsid protein p11 (NC); Ty3 protease (PR) (EC 3.4.23.-) (p16); Spacer peptide J; Reverse transcriptase/ribonuclease H (RT) (RT-RH) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p55); Integrase p61 (IN); Integrase p58 (IN)] Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508]; transposition, RNA-mediated [GO:0032197] GO:0000943; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004540; GO:0005524; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0008233; GO:0008270; GO:0015074; GO:0032197 33525 FUN_030067 6 9 0 0 55 NA NA NA NA NA NA NA 33526 FUN_030066 16 90 27 0 30 NA NA NA NA NA NA NA 33527 FUN_030069 1251 460 30 811 506 ptg000023l:9072259-9083348 Q7RTR2 3.18e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33528 FUN_030069 1251 460 30 811 506 ptg000023l:9072259-9083348 Q7RTR2 2.5e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33529 FUN_030069 1251 460 30 811 506 ptg000023l:9072259-9083348 Q7RTR2 3.06e-41 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33530 FUN_030069 1251 460 30 811 506 ptg000023l:9072259-9083348 Q7RTR2 8.76e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 33531 FUN_030068 92 97 15 187 97 NA NA NA NA NA NA NA 33532 FUN_019428 0 25 0 0 12 NA NA NA NA NA NA NA 33533 FUN_019429 0 0 0 0 28 NA NA NA NA NA NA NA 33534 FUN_001850 204 686 330 693 354 NA NA NA NA NA NA NA 33535 FUN_001851 441 303 304 339 491 NA NA NA NA NA NA NA 33536 FUN_001852 235 213 67 207 145 NA NA NA NA NA NA NA 33537 FUN_001853 2999 3022 1440 2216 1016 NA NA NA NA NA NA NA 33538 FUN_001854 1276 1315 1176 1240 816 NA NA NA NA NA NA NA 33539 FUN_001855 145 106 0 110 54 NA NA NA NA NA NA NA 33540 FUN_001856 677 306 347 844 505 ntLink_6:17063911-17090590 P04323 1.2e-60 Retrovirus-related Pol polyprotein from transposon 17.6 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 33541 FUN_001857 75 68 19 32 19 NA NA NA NA NA NA NA 33542 FUN_001858 86 130 75 42 29 NA NA NA NA NA NA NA 33543 FUN_001859 99 140 169 94 21 NA NA NA NA NA NA NA 33544 FUN_024008 168 109 10 25 56 NA NA NA NA NA NA NA 33545 FUN_024009 716 698 280 613 319 NA NA NA NA NA NA NA 33546 FUN_024002 2531 1403 1118 1846 2035 NA NA NA NA NA NA NA 33547 FUN_024003 2559 1895 1367 2120 1201 NA NA NA NA NA NA NA 33548 FUN_024000 346 283 145 214 337 ptg000018l:1030667-1041036 Q5E9U6 1.2e-43 Protein Wnt-16 Bos taurus (Bovine) Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055 33549 FUN_024000 346 283 145 214 337 ptg000018l:1030667-1041036 Q5E9U6 2.15e-29 Protein Wnt-16 Bos taurus (Bovine) Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055 33550 FUN_024000 346 283 145 214 337 ptg000018l:1030667-1041036 Q5E9U6 2.15e-29 Protein Wnt-16 Bos taurus (Bovine) Wnt signaling pathway [GO:0016055] GO:0005102; GO:0005576; GO:0016055 33551 FUN_024001 2520 1485 932 1552 1501 ptg000018l:1041246-1062777 P00532 1.09e-22 Serine/threonine-protein kinase-transforming protein raf (EC 2.7.11.1) Murine sarcoma virus 3611 protein phosphorylation [GO:0006468] GO:0004674; GO:0005524; GO:0006468; GO:0106310 33552 FUN_024006 4216 4372 2929 3548 2446 NA NA NA NA NA NA NA 33553 FUN_024007 323 173 74 163 198 NA NA NA NA NA NA NA 33554 FUN_024004 508 318 254 373 310 NA NA NA NA NA NA NA 33555 FUN_024005 1665 652 700 1011 890 NA NA NA NA NA NA NA 33556 FUN_038188 952 297 331 699 541 NA NA NA NA NA NA NA 33557 FUN_038186 235 361 182 526 115 NA NA NA NA NA NA NA 33558 FUN_038187 2584 697 2460 2027 2868 ptg000027l:3559033-3608665 Q86WI1 0 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 33559 FUN_038187 2584 697 2460 2027 2868 ptg000027l:3559033-3608665 Q86WI1 7.47e-52 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 33560 FUN_038187 2584 697 2460 2027 2868 ptg000027l:3559033-3608665 Q86WI1 1.51e-39 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 33561 FUN_038187 2584 697 2460 2027 2868 ptg000027l:3559033-3608665 Q86WI1 2.2e-22 Fibrocystin-L (Polycystic kidney and hepatic disease 1-like protein 1) (PKHD1-like protein 1) Homo sapiens (Human) immune response [GO:0006955]; sensory perception of sound [GO:0007605] GO:0005615; GO:0005829; GO:0006955; GO:0007605; GO:0016020; GO:0032426; GO:0038023; GO:0120234 33562 FUN_038182 2895 1573 1006 2483 2507 ptg000027l:3501615-3530723 O14981 1.07e-28 TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003712; GO:0004386; GO:0005524; GO:0005654; GO:0008094; GO:0016887; GO:0017025; GO:0035562; GO:0043231; GO:0045892; GO:0140658 33563 FUN_038182 2895 1573 1006 2483 2507 ptg000027l:3501615-3530723 O14981 1.07e-28 TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003712; GO:0004386; GO:0005524; GO:0005654; GO:0008094; GO:0016887; GO:0017025; GO:0035562; GO:0043231; GO:0045892; GO:0140658 33564 FUN_038182 2895 1573 1006 2483 2507 ptg000027l:3501615-3530723 O14981 4.49e-27 TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003712; GO:0004386; GO:0005524; GO:0005654; GO:0008094; GO:0016887; GO:0017025; GO:0035562; GO:0043231; GO:0045892; GO:0140658 33565 FUN_038182 2895 1573 1006 2483 2507 ptg000027l:3501615-3530723 O14981 4.49e-27 TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172) Homo sapiens (Human) negative regulation of chromatin binding [GO:0035562]; negative regulation of DNA-templated transcription [GO:0045892] GO:0003677; GO:0003712; GO:0004386; GO:0005524; GO:0005654; GO:0008094; GO:0016887; GO:0017025; GO:0035562; GO:0043231; GO:0045892; GO:0140658 33566 FUN_038183 462 405 266 214 181 NA NA NA NA NA NA NA 33567 FUN_038180 1699 3924 576 937 472 NA NA NA NA NA NA NA 33568 FUN_038181 1640 1155 657 1096 1878 ptg000027l:3492298-3499989 Q9ES54 1.14e-22 Nuclear protein localization protein 4 homolog (Protein NPL4) Rattus norvegicus (Rat) Golgi organization [GO:0007030]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005829; GO:0006511; GO:0007030; GO:0030433; GO:0030970; GO:0031625; GO:0032480; GO:0034098; GO:0036501; GO:0039536; GO:0043130; GO:0044877; GO:0046872; GO:0051117 33569 FUN_038181 1640 1155 657 1096 1878 ptg000027l:3492298-3499989 Q9ES54 5.06e-21 Nuclear protein localization protein 4 homolog (Protein NPL4) Rattus norvegicus (Rat) Golgi organization [GO:0007030]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; retrograde protein transport, ER to cytosol [GO:0030970]; ubiquitin-dependent ERAD pathway [GO:0030433]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0005634; GO:0005829; GO:0006511; GO:0007030; GO:0030433; GO:0030970; GO:0031625; GO:0032480; GO:0034098; GO:0036501; GO:0039536; GO:0043130; GO:0044877; GO:0046872; GO:0051117 33570 FUN_043375 1285 812 582 931 1065 NA NA NA NA NA NA NA 33571 FUN_007136 237 79 91 151 109 NA NA NA NA NA NA NA 33572 FUN_027674 50 0 21 35 0 NA NA NA NA NA NA NA 33573 FUN_027676 62 7 13 8 16 NA NA NA NA NA NA NA 33574 FUN_021984 0 0 21 0 1 NA NA NA NA NA NA NA 33575 FUN_021985 177 64 120 313 221 NA NA NA NA NA NA NA 33576 FUN_021986 189 116 60 261 84 NA NA NA NA NA NA NA 33577 FUN_021980 0 0 0 0 8 NA NA NA NA NA NA NA 33578 FUN_021989 0 9 0 0 0 NA NA NA NA NA NA NA 33579 FUN_027588 49 0 20 2 0 NA NA NA NA NA NA NA 33580 FUN_027589 0 0 0 0 43 NA NA NA NA NA NA NA 33581 FUN_027580 0 15 7 0 0 NA NA NA NA NA NA NA 33582 FUN_031008 0 0 0 85 0 NA NA NA NA NA NA NA 33583 FUN_031009 0 0 5 0 14 NA NA NA NA NA NA NA 33584 FUN_036058 509 295 208 342 497 NA NA NA NA NA NA NA 33585 FUN_036059 1454 875 726 1383 677 NA NA NA NA NA NA NA 33586 FUN_031000 0 0 0 0 8 NA NA NA NA NA NA NA 33587 FUN_036057 1220 1500 476 1079 1136 NA NA NA NA NA NA NA 33588 FUN_036054 978 1682 755 778 1017 NA NA NA NA NA NA NA 33589 FUN_031003 439 87 100 109 56 NA NA NA NA NA NA NA 33590 FUN_036052 125 59 12 58 19 NA NA NA NA NA NA NA 33591 FUN_036053 1778 773 720 1423 859 NA NA NA NA NA NA NA 33592 FUN_031006 74 0 69 19 213 NA NA NA NA NA NA NA 33593 FUN_036051 558 148 71 206 69 NA NA NA NA NA NA NA 33594 FUN_006008 32 11 0 27 37 ptg000001l:6707349-6710701 Q03601 5e-23 RING finger protein nhl-1 Caenorhabditis elegans negative regulation of translation [GO:0017148]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567] GO:0000209; GO:0004842; GO:0016567; GO:0017148; GO:0030371; GO:0043161; GO:0046872; GO:0061630 33595 FUN_006009 0 141 50 130 115 NA NA NA NA NA NA NA 33596 FUN_006006 2545 2924 1576 2167 2171 NA NA NA NA NA NA NA 33597 FUN_006007 19 0 17 19 151 ptg000001l:6704374-6706715 Q9D411 6.85e-57 Testis-specific serine/threonine-protein kinase 4 (TSK-4) (TSSK-4) (Testis-specific kinase 4) (EC 2.7.11.1) Mus musculus (Mouse) fertilization [GO:0009566]; flagellated sperm motility [GO:0030317]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of CREB transcription factor activity [GO:0032793]; protein phosphorylation [GO:0006468]; spermatid development [GO:0007286] GO:0000287; GO:0001669; GO:0004672; GO:0004674; GO:0005524; GO:0006468; GO:0007286; GO:0009566; GO:0018105; GO:0030317; GO:0031514; GO:0032793; GO:0035556; GO:0036126; GO:0042802; GO:0042803; GO:0044877; GO:0106310; GO:1990443 33598 FUN_006004 619 542 418 675 585 NA NA NA NA NA NA NA 33599 FUN_006005 718 761 427 586 570 NA NA NA NA NA NA NA 33600 FUN_006002 3457 1987 2179 3434 2678 ptg000001l:6657862-6675861 P40806 1.57e-24 Polyketide synthase PksJ (PKS) Bacillus subtilis (strain 168) antibiotic biosynthetic process [GO:0017000]; DIM/DIP cell wall layer assembly [GO:0071770]; fatty acid biosynthetic process [GO:0006633] GO:0004312; GO:0004315; GO:0005737; GO:0006633; GO:0016874; GO:0017000; GO:0031177; GO:0071770 33601 FUN_006003 1776 2405 1124 1844 1488 NA NA NA NA NA NA NA 33602 FUN_006000 2841 680 950 448 389 ptg000001l:6650684-6653842 Q8CIH9 1.13e-159 Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; glutamine catabolic process [GO:0006543]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; ribose phosphate metabolic process [GO:0019693] GO:0004044; GO:0006164; GO:0006177; GO:0006189; GO:0006543; GO:0009113; GO:0009168; GO:0019693; GO:0042802; GO:0044208; GO:0046872; GO:0051539; GO:0097294 33603 FUN_006000 2841 680 950 448 389 ptg000001l:6650684-6653842 Q8CIH9 1.09e-26 Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT) Mus musculus (Mouse) 'de novo' AMP biosynthetic process [GO:0044208]; 'de novo' IMP biosynthetic process [GO:0006189]; 'de novo' XMP biosynthetic process [GO:0097294]; glutamine catabolic process [GO:0006543]; GMP biosynthetic process [GO:0006177]; purine nucleobase biosynthetic process [GO:0009113]; purine nucleotide biosynthetic process [GO:0006164]; purine ribonucleoside monophosphate biosynthetic process [GO:0009168]; ribose phosphate metabolic process [GO:0019693] GO:0004044; GO:0006164; GO:0006177; GO:0006189; GO:0006543; GO:0009113; GO:0009168; GO:0019693; GO:0042802; GO:0044208; GO:0046872; GO:0051539; GO:0097294 33604 FUN_006001 2077 2439 1181 2172 1938 ptg000001l:6655254-6656247 P38024 6.34e-145 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase); Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) (AIR carboxylase) (AIRC)] Gallus gallus (Chicken) 'de novo' IMP biosynthetic process [GO:0006189] GO:0004638; GO:0004639; GO:0005524; GO:0005829; GO:0006189; GO:0043727 33605 FUN_026985 167 296 179 246 167 NA NA NA NA NA NA NA 33606 FUN_013365 5543 3992 3343 5749 4862 ptg000008l:21694135-21709784 Q4PZA2 4.3e-36 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Mus musculus (Mouse) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to hypoxia [GO:0001666]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005794; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009897; GO:0009986; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 33607 FUN_026987 0 0 0 0 6 NA NA NA NA NA NA NA 33608 FUN_026986 147 77 129 165 171 NA NA NA NA NA NA NA 33609 FUN_026981 1354 829 423 564 437 ptg000020l:15450200-15471949 O60290 1.12e-62 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 33610 FUN_026981 1354 829 423 564 437 ptg000020l:15450200-15471949 O60290 1.12e-62 Zinc finger protein 862 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0005634; GO:0006355; GO:0046872; GO:0046983 33611 FUN_026980 706 478 252 426 495 NA NA NA NA NA NA NA 33612 FUN_026983 658 439 291 1028 993 ptg000020l:15485521-15488210 Q5SPP5 0 Protein EFR3 homolog B Danio rerio (Zebrafish) (Brachydanio rerio) phosphatidylinositol phosphate biosynthetic process [GO:0046854]; protein localization to plasma membrane [GO:0072659] GO:0005886; GO:0046854; GO:0072659 33613 FUN_026989 3190 3000 1801 2140 2703 NA NA NA NA NA NA NA 33614 FUN_041207 0 0 9 6 78 NA NA NA NA NA NA NA 33615 FUN_037091 1476 967 867 1500 1956 NA NA NA NA NA NA NA 33616 FUN_037090 2966 2451 1169 3000 1621 NA NA NA NA NA NA NA 33617 FUN_037093 1182 1559 493 1293 1469 NA NA NA NA NA NA NA 33618 FUN_037092 1081 1983 1134 1638 1209 NA NA NA NA NA NA NA 33619 FUN_037095 542 487 201 401 552 NA NA NA NA NA NA NA 33620 FUN_037094 143 81 77 178 2 NA NA NA NA NA NA NA 33621 FUN_037097 1162 740 568 1182 1191 NA NA NA NA NA NA NA 33622 FUN_037096 100 69 51 47 200 NA NA NA NA NA NA NA 33623 FUN_037099 9 2 0 9 1 NA NA NA NA NA NA NA 33624 FUN_037098 27 14 59 29 0 NA NA NA NA NA NA NA 33625 FUN_013360 41 39 0 56 41 NA NA NA NA NA NA NA 33626 FUN_029470 180 1747 113 102 170 ptg000023l:2206284-2235124 P0CT40 4.29e-37 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 33627 FUN_029470 180 1747 113 102 170 ptg000023l:2206284-2235124 P0CT40 4.29e-37 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 33628 FUN_013363 378 212 63 125 135 ptg000008l:21685065-21686990 Q5R5U1 4.28e-30 Ras-related protein Rab-10 (EC 3.6.5.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) antigen processing and presentation [GO:0019882]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; endoplasmic reticulum tubular network organization [GO:0071786]; endosomal transport [GO:0016197]; establishment of neuroblast polarity [GO:0045200]; establishment of protein localization to endoplasmic reticulum membrane [GO:0097051]; Golgi to plasma membrane protein transport [GO:0043001]; Golgi to plasma membrane transport [GO:0006893]; polarized epithelial cell differentiation [GO:0030859]; protein localization to basolateral plasma membrane [GO:1903361]; protein localization to plasma membrane [GO:0072659]; regulated exocytosis [GO:0045055]; vesicle-mediated transport [GO:0016192] GO:0003925; GO:0005525; GO:0005768; GO:0005789; GO:0005794; GO:0005802; GO:0005886; GO:0005929; GO:0006893; GO:0007409; GO:0016192; GO:0016197; GO:0019003; GO:0019882; GO:0030670; GO:0030859; GO:0031489; GO:0032593; GO:0032869; GO:0043001; GO:0045055; GO:0045200; GO:0048471; GO:0055037; GO:0055038; GO:0070382; GO:0071782; GO:0071786; GO:0072659; GO:0097051; GO:1903361 33629 FUN_040272 484 241 221 364 412 ptg000031l:6181389-6182334 Q8VE97 7.96e-40 Serine/arginine-rich splicing factor 4 (Splicing factor, arginine/serine-rich 4) Mus musculus (Mouse) hematopoietic progenitor cell differentiation [GO:0002244]; mRNA splicing, via spliceosome [GO:0000398]; negative regulation of mRNA splicing, via spliceosome [GO:0048025] GO:0000398; GO:0002244; GO:0003723; GO:0003729; GO:0005634; GO:0016607; GO:0048025; GO:1990825 33630 FUN_042201 12 27 6 4 12 NA NA NA NA NA NA NA 33631 FUN_042202 20 32 23 35 79 NA NA NA NA NA NA NA 33632 FUN_004530 222 251 75 294 106 NA NA NA NA NA NA NA 33633 FUN_004531 6 0 8 369 22 NA NA NA NA NA NA NA 33634 FUN_004532 0 11 0 0 0 NA NA NA NA NA NA NA 33635 FUN_004533 313 255 134 446 197 NA NA NA NA NA NA NA 33636 FUN_004534 86 121 36 171 71 NA NA NA NA NA NA NA 33637 FUN_004535 222 157 183 281 402 NA NA NA NA NA NA NA 33638 FUN_004536 68 33 15 26 66 NA NA NA NA NA NA NA 33639 FUN_004537 0 25 17 23 49 NA NA NA NA NA NA NA 33640 FUN_004538 0 0 0 27 0 NA NA NA NA NA NA NA 33641 FUN_004539 0 0 3 68 0 NA NA NA NA NA NA NA 33642 FUN_007841 2393 2392 1619 1504 1477 NA NA NA NA NA NA NA 33643 FUN_007840 4741 3918 3104 3141 2547 NA NA NA NA NA NA NA 33644 FUN_007843 3706 5352 2458 4521 1436 NA NA NA NA NA NA NA 33645 FUN_007842 1182 994 672 1069 635 NA NA NA NA NA NA NA 33646 FUN_007845 401 207 144 88 226 NA NA NA NA NA NA NA 33647 FUN_007844 175 328 359 317 394 NA NA NA NA NA NA NA 33648 FUN_007847 424 168 133 190 274 NA NA NA NA NA NA NA 33649 FUN_007846 8381 3412 3127 5658 4790 ptg000002l:5365209-5372657 G5ECR9 9.2e-25 Nuclear hormone receptor unc-55 (Uncoordinated protein 55) Caenorhabditis elegans cell differentiation [GO:0030154]; cell fate specification [GO:0001708]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0000122; GO:0000978; GO:0001708; GO:0004879; GO:0005634; GO:0008270; GO:0030154; GO:0045944 33650 FUN_007849 2575 1179 1655 2648 1905 NA NA NA NA NA NA NA 33651 FUN_007848 1067 1041 629 1169 844 NA NA NA NA NA NA NA 33652 FUN_033577 0 4 0 14 182 NA NA NA NA NA NA NA 33653 FUN_033574 0 0 0 0 6 NA NA NA NA NA NA NA 33654 FUN_035930 10466 7884 5280 11788 7052 NA NA NA NA NA NA NA 33655 FUN_035931 2021 1930 1183 2021 1463 ptg000025l:13408104-13409228 Q5P203 5.08e-39 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase (HMG aldolase) (EC 4.1.3.17) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) (Regulator of ribonuclease activity homolog) (RraA-like protein) Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) regulation of RNA metabolic process [GO:0051252] GO:0008428; GO:0008948; GO:0046872; GO:0047443; GO:0051252 33656 FUN_035932 57 132 135 207 293 ptg000025l:13428763-13429303 Q9I993 7.6e-43 Beta,beta-carotene 15,15'-dioxygenase (EC 1.13.11.63) (Beta-carotene dioxygenase 1) (Beta-carotene oxygenase 1) Gallus gallus (Chicken) beta-carotene metabolic process [GO:1901810]; carotene catabolic process [GO:0016121]; response to retinoic acid [GO:0032526]; retinal metabolic process [GO:0042574]; retinoid metabolic process [GO:0001523]; retinol metabolic process [GO:0042572] GO:0001523; GO:0003834; GO:0004497; GO:0005829; GO:0010436; GO:0016121; GO:0032526; GO:0042572; GO:0042574; GO:0046872; GO:1901810 33657 FUN_035933 223 170 152 471 441 ptg000025l:13435343-13436408 Q99NF1 3.38e-62 Carotenoid-cleaving dioxygenase, mitochondrial (EC 1.13.11.-) (EC 1.13.11.71) (B-diox-II) (Beta,beta-carotene 9',10'-oxygenase) (Beta-carotene dioxygenase 2) Mus musculus (Mouse) carotene catabolic process [GO:0016121]; carotene metabolic process [GO:0016119]; carotenoid metabolic process [GO:0016116]; lutein catabolic process [GO:0062172]; lycopene catabolic process [GO:1901176]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377]; retinal metabolic process [GO:0042574]; retinoic acid metabolic process [GO:0042573]; xanthophyll catabolic process [GO:0016124]; xanthophyll metabolic process [GO:0016122]; zeaxanthin catabolic process [GO:1901826] GO:0003834; GO:0005739; GO:0010436; GO:0010437; GO:0016116; GO:0016119; GO:0016121; GO:0016122; GO:0016124; GO:0016702; GO:0042573; GO:0042574; GO:0046872; GO:0051881; GO:0062172; GO:0102076; GO:1901176; GO:1901826; GO:2000377 33658 FUN_035934 271 321 116 204 229 NA NA NA NA NA NA NA 33659 FUN_035935 6742 3514 2879 2640 2738 ptg000025l:13443923-13447956 P23709 1.72e-25 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (EC 7.1.1.2) (Complex I-30kD) (CI-30kD) (NADH-ubiquinone oxidoreductase 30 kDa subunit) Bos taurus (Bovine) mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981]; negative regulation of cell growth [GO:0030308]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; reactive oxygen species metabolic process [GO:0072593] GO:0003954; GO:0005743; GO:0005747; GO:0006120; GO:0008137; GO:0030308; GO:0031966; GO:0032981; GO:0072593; GO:2001243 33660 FUN_035936 1266 507 789 578 662 NA NA NA NA NA NA NA 33661 FUN_035938 59 211 16 69 44 NA NA NA NA NA NA NA 33662 FUN_035939 42 43 27 25 13 NA NA NA NA NA NA NA 33663 FUN_024247 94 23 12 0 7 NA NA NA NA NA NA NA 33664 FUN_004398 846 522 479 1228 778 NA NA NA NA NA NA NA 33665 FUN_004399 381 282 199 379 831 NA NA NA NA NA NA NA 33666 FUN_004394 493 232 332 321 721 NA NA NA NA NA NA NA 33667 FUN_004395 325 0 280 639 303 NA NA NA NA NA NA NA 33668 FUN_004396 207 54 134 171 308 NA NA NA NA NA NA NA 33669 FUN_004397 7 0 0 4 4 NA NA NA NA NA NA NA 33670 FUN_004390 100 186 99 148 254 NA NA NA NA NA NA NA 33671 FUN_004391 9 1 12 0 70 NA NA NA NA NA NA NA 33672 FUN_004393 1325 491 997 559 1430 NA NA NA NA NA NA NA 33673 FUN_041717 845 610 580 813 714 ptg000035l:6771396-6772107 Q9CX47 2.84e-47 DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2) Mus musculus (Mouse) cellular response to DNA damage stimulus [GO:0006974]; centrosome cycle [GO:0007098]; DNA repair [GO:0006281]; double-strand break repair via homologous recombination [GO:0000724]; in utero embryonic development [GO:0001701]; mitotic cell cycle [GO:0000278]; multicellular organism growth [GO:0035264]; negative regulation of neuron apoptotic process [GO:0043524]; neurogenesis [GO:0022008]; positive regulation of neurogenesis [GO:0050769]; regulation of fibroblast apoptotic process [GO:2000269]; response to gamma radiation [GO:0010332]; response to X-ray [GO:0010165]; somitogenesis [GO:0001756]; strand invasion [GO:0042148] GO:0000278; GO:0000400; GO:0000724; GO:0001701; GO:0001756; GO:0005524; GO:0005654; GO:0005657; GO:0005813; GO:0006281; GO:0006974; GO:0007098; GO:0010165; GO:0010332; GO:0022008; GO:0033063; GO:0035264; GO:0042148; GO:0043231; GO:0043524; GO:0050769; GO:0140664; GO:2000269 33674 FUN_041716 2170 1372 896 1587 1010 NA NA NA NA NA NA NA 33675 FUN_041715 42 12 37 0 45 NA NA NA NA NA NA NA 33676 FUN_041714 36 15 0 14 108 NA NA NA NA NA NA NA 33677 FUN_018438 338 502 221 513 414 NA NA NA NA NA NA NA 33678 FUN_018439 3896 4581 2147 3658 5030 NA NA NA NA NA NA NA 33679 FUN_018434 706 530 664 833 396 NA NA NA NA NA NA NA 33680 FUN_041713 34 21 9 14 23 NA NA NA NA NA NA NA 33681 FUN_018436 3869 3179 1815 2719 4338 NA NA NA NA NA NA NA 33682 FUN_018437 202 277 116 328 278 NA NA NA NA NA NA NA 33683 FUN_018430 582 886 861 2233 869 NA NA NA NA NA NA NA 33684 FUN_018431 557 960 0 1081 907 NA NA NA NA NA NA NA 33685 FUN_018432 1124 1893 607 2418 1436 NA NA NA NA NA NA NA 33686 FUN_018433 76 199 97 4 103 NA NA NA NA NA NA NA 33687 FUN_006828 54 0 0 35 14 NA NA NA NA NA NA NA 33688 FUN_006829 19 38 56 81 53 NA NA NA NA NA NA NA 33689 FUN_041711 3181 4752 3466 3306 1951 NA NA NA NA NA NA NA 33690 FUN_003934 0 10 48 45 64 NA NA NA NA NA NA NA 33691 FUN_006820 1503 1190 915 1968 474 NA NA NA NA NA NA NA 33692 FUN_006821 2177 1139 1038 1824 1624 ptg000001l:17049432-17061639 Q9HD45 2.19e-27 Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein) Homo sapiens (Human) protein localization to membrane [GO:0072657] GO:0016020; GO:0072657 33693 FUN_006822 375 216 286 329 478 NA NA NA NA NA NA NA 33694 FUN_041710 925 518 554 796 900 ptg000035l:6737981-6752397 Q5LUF3 3.38e-27 Propionyl-CoA carboxylase alpha chain (EC 6.4.1.3) Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) lipid catabolic process [GO:0016042] GO:0004658; GO:0005524; GO:0016042; GO:0046872 33695 FUN_006824 34 14 15 48 125 NA NA NA NA NA NA NA 33696 FUN_006826 284 182 179 236 206 NA NA NA NA NA NA NA 33697 FUN_006827 18 59 103 40 13 NA NA NA NA NA NA NA 33698 FUN_035066 191 105 69 98 116 ptg000025l:3416199-3417066 Q8LET2 2.86e-38 Nudix hydrolase 11 (AtNUDT11) (EC 3.6.1.-) (Coenzyme A diphosphatase NUDT11) Arabidopsis thaliana (Mouse-ear cress) coenzyme A biosynthetic process [GO:0015937]; coenzyme A catabolic process [GO:0015938]; malonyl-CoA catabolic process [GO:2001294]; nucleoside phosphate metabolic process [GO:0006753] GO:0000210; GO:0003986; GO:0005778; GO:0005829; GO:0006753; GO:0008893; GO:0010945; GO:0015937; GO:0015938; GO:0046872; GO:2001294 33699 FUN_035067 294 282 243 291 553 NA NA NA NA NA NA NA 33700 FUN_035064 757 788 851 301 470 ptg000025l:3390245-3401227 O00370 1.78e-60 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 33701 FUN_035064 757 788 851 301 470 ptg000025l:3390245-3401227 O00370 1.78e-60 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 33702 FUN_035064 757 788 851 301 470 ptg000025l:3390245-3401227 O00370 1.38e-22 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 33703 FUN_035065 2128 1261 1075 1979 2010 NA NA NA NA NA NA NA 33704 FUN_035062 248 583 359 156 260 NA NA NA NA NA NA NA 33705 FUN_035063 0 0 17 0 0 NA NA NA NA NA NA NA 33706 FUN_035060 6011 5522 4084 4080 3201 NA NA NA NA NA NA NA 33707 FUN_035061 294 326 210 96 214 NA NA NA NA NA NA NA 33708 FUN_036535 73 980 212 78 204 NA NA NA NA NA NA NA 33709 FUN_035068 501 109 177 466 772 NA NA NA NA NA NA NA 33710 FUN_035069 446 259 175 228 266 NA NA NA NA NA NA NA 33711 FUN_003377 0 0 17 3 31 NA NA NA NA NA NA NA 33712 FUN_028112 39 3 4 32 12 NA NA NA NA NA NA NA 33713 FUN_028115 1133 1115 760 1182 1235 NA NA NA NA NA NA NA 33714 FUN_028117 3311 2739 2007 2448 2338 NA NA NA NA NA NA NA 33715 FUN_028118 1487 783 483 1299 727 NA NA NA NA NA NA NA 33716 FUN_028119 296 199 115 341 309 NA NA NA NA NA NA NA 33717 FUN_003379 10 47 57 73 85 NA NA NA NA NA NA NA 33718 FUN_043351 1447 1114 1334 1060 962 NA NA NA NA NA NA NA 33719 FUN_043352 1700 921 818 1264 797 NA NA NA NA NA NA NA 33720 FUN_043355 2270 1583 1322 1551 1691 NA NA NA NA NA NA NA 33721 FUN_043354 389 208 136 210 128 NA NA NA NA NA NA NA 33722 FUN_043357 7 2 0 0 0 NA NA NA NA NA NA NA 33723 FUN_043356 199 64 141 410 140 ptg000047l:7512433-7518348 Q9VE46 2.15e-39 High-affinity choline transporter 1 Drosophila melanogaster (Fruit fly) acetylcholine biosynthetic process [GO:0008292]; amino acid transmembrane transport [GO:0003333]; choline transport [GO:0015871] GO:0003333; GO:0005307; GO:0005886; GO:0008292; GO:0015171; GO:0015220; GO:0015871; GO:0016020 33724 FUN_043356 199 64 141 410 140 ptg000047l:7512433-7518348 Q9VE46 6.52e-31 High-affinity choline transporter 1 Drosophila melanogaster (Fruit fly) acetylcholine biosynthetic process [GO:0008292]; amino acid transmembrane transport [GO:0003333]; choline transport [GO:0015871] GO:0003333; GO:0005307; GO:0005886; GO:0008292; GO:0015171; GO:0015220; GO:0015871; GO:0016020 33725 FUN_043359 2488 648 249 1024 124 ptg000047l:7530892-7537465 Q9VE46 1.35e-41 High-affinity choline transporter 1 Drosophila melanogaster (Fruit fly) acetylcholine biosynthetic process [GO:0008292]; amino acid transmembrane transport [GO:0003333]; choline transport [GO:0015871] GO:0003333; GO:0005307; GO:0005886; GO:0008292; GO:0015171; GO:0015220; GO:0015871; GO:0016020 33726 FUN_043359 2488 648 249 1024 124 ptg000047l:7530892-7537465 Q9VE46 2.02e-27 High-affinity choline transporter 1 Drosophila melanogaster (Fruit fly) acetylcholine biosynthetic process [GO:0008292]; amino acid transmembrane transport [GO:0003333]; choline transport [GO:0015871] GO:0003333; GO:0005307; GO:0005886; GO:0008292; GO:0015171; GO:0015220; GO:0015871; GO:0016020 33727 FUN_043358 49 4 5 6 0 NA NA NA NA NA NA NA 33728 FUN_042086 2 0 5 10 5 ptg000036l:443196-445524 Q9SZJ2 1.87e-37 Glycine-rich domain-containing protein 2 (AtGRDP2) Arabidopsis thaliana (Mouse-ear cress) auxin-activated signaling pathway [GO:0009734]; cellular response to osmotic stress [GO:0071470]; regulation of auxin mediated signaling pathway [GO:0010928]; regulation of photoperiodism, flowering [GO:2000028] GO:0009734; GO:0010928; GO:0071470; GO:2000028 33729 FUN_042084 0 0 0 88 19 NA NA NA NA NA NA NA 33730 FUN_042082 3 191 0 225 52 NA NA NA NA NA NA NA 33731 FUN_042083 4 333 2 204 0 NA NA NA NA NA NA NA 33732 FUN_042080 0 3 0 16 0 NA NA NA NA NA NA NA 33733 FUN_041263 15 15 0 21 33 NA NA NA NA NA NA NA 33734 FUN_041262 296 175 70 298 167 NA NA NA NA NA NA NA 33735 FUN_041261 2 0 2 0 19 NA NA NA NA NA NA NA 33736 FUN_041265 1778 1152 914 1546 1212 NA NA NA NA NA NA NA 33737 FUN_041264 3163 1843 844 1076 1024 NA NA NA NA NA NA NA 33738 FUN_043683 0 0 17 0 3 NA NA NA NA NA NA NA 33739 FUN_043685 0 0 50 11 16 NA NA NA NA NA NA NA 33740 FUN_011267 42 182 216 89 675 NA NA NA NA NA NA NA 33741 FUN_003953 10 202 68 43 0 NA NA NA NA NA NA NA 33742 FUN_003952 5 69 0 0 11 NA NA NA NA NA NA NA 33743 FUN_003951 2 6 0 10 6 NA NA NA NA NA NA NA 33744 FUN_003950 23 0 11 28 0 NA NA NA NA NA NA NA 33745 FUN_003957 53 106 109 68 80 NA NA NA NA NA NA NA 33746 FUN_041198 3 11 15 10 51 NA NA NA NA NA NA NA 33747 FUN_003955 0 0 10 0 42 NA NA NA NA NA NA NA 33748 FUN_003954 0 8 0 5 0 NA NA NA NA NA NA NA 33749 FUN_041195 78 64 88 93 326 NA NA NA NA NA NA NA 33750 FUN_041194 0 6 1 0 0 NA NA NA NA NA NA NA 33751 FUN_041197 38 12 17 0 0 NA NA NA NA NA NA NA 33752 FUN_041190 521 630 147 398 215 NA NA NA NA NA NA NA 33753 FUN_041193 21 21 37 62 58 NA NA NA NA NA NA NA 33754 FUN_041192 384 417 299 516 252 NA NA NA NA NA NA NA 33755 FUN_002024 0 177 41 0 14 NA NA NA NA NA NA NA 33756 FUN_002025 0 18 51 19 9 NA NA NA NA NA NA NA 33757 FUN_002026 7 0 12 8 25 NA NA NA NA NA NA NA 33758 FUN_002021 18 0 28 0 13 NA NA NA NA NA NA NA 33759 FUN_002022 0 0 0 12 0 NA NA NA NA NA NA NA 33760 FUN_002029 0 8 591 103 20 NA NA NA NA NA NA NA 33761 FUN_029237 33 81 52 124 125 NA NA NA NA NA NA NA 33762 FUN_012661 1157 655 610 721 1113 ptg000008l:11021345-11027189 A3KQ55 2.67e-29 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog) (zBCDIN3) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031] GO:0001510; GO:0005634; GO:0008171; GO:0008173; GO:0008757; GO:0016073; GO:0017069; GO:0040031; GO:1904871; GO:1905382; GO:1990276; GO:1990904 33763 FUN_012661 1157 655 610 721 1113 ptg000008l:11021345-11027189 A3KQ55 5.23e-23 7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog) (zBCDIN3) Danio rerio (Zebrafish) (Brachydanio rerio) positive regulation of protein localization to Cajal body [GO:1904871]; positive regulation of snRNA transcription by RNA polymerase II [GO:1905382]; RNA methylation [GO:0001510]; snRNA metabolic process [GO:0016073]; snRNA modification [GO:0040031] GO:0001510; GO:0005634; GO:0008171; GO:0008173; GO:0008757; GO:0016073; GO:0017069; GO:0040031; GO:1904871; GO:1905382; GO:1990276; GO:1990904 33764 FUN_029235 40 18 4 14 50 NA NA NA NA NA NA NA 33765 FUN_029098 178 57 47 87 56 ptg000022l:8238014-8247336 Q9Y210 1.12e-31 Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ion transmembrane transporter activity [GO:0032414]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] GO:0005261; GO:0005262; GO:0005737; GO:0005886; GO:0006812; GO:0007204; GO:0007338; GO:0015279; GO:0016020; GO:0032414; GO:0034703; GO:0036057; GO:0042803; GO:0051480; GO:0051928; GO:0070588; GO:0070679 33766 FUN_029098 178 57 47 87 56 ptg000022l:8238014-8247336 Q9Y210 3.68e-25 Short transient receptor potential channel 6 (TrpC6) (Transient receptor protein 6) (TRP-6) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cation transport [GO:0006812]; positive regulation of calcium ion transport [GO:0051928]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of ion transmembrane transporter activity [GO:0032414]; regulation of cytosolic calcium ion concentration [GO:0051480]; single fertilization [GO:0007338] GO:0005261; GO:0005262; GO:0005737; GO:0005886; GO:0006812; GO:0007204; GO:0007338; GO:0015279; GO:0016020; GO:0032414; GO:0034703; GO:0036057; GO:0042803; GO:0051480; GO:0051928; GO:0070588; GO:0070679 33767 FUN_032914 165 576 37 112 91 NA NA NA NA NA NA NA 33768 FUN_029233 71 11 94 68 59 NA NA NA NA NA NA NA 33769 FUN_042559 24 2 43 3 97 ptg000038l:225263-226632 Q6LAF1 1.82e-48 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33770 FUN_043235 426 292 438 898 773 NA NA NA NA NA NA NA 33771 FUN_029230 93 72 118 102 103 NA NA NA NA NA NA NA 33772 FUN_029095 699 491 332 563 556 NA NA NA NA NA NA NA 33773 FUN_012955 0 0 12 0 3 NA NA NA NA NA NA NA 33774 FUN_012954 45 24 7 25 10 NA NA NA NA NA NA NA 33775 FUN_012957 0 0 6 3 13 NA NA NA NA NA NA NA 33776 FUN_012956 1 0 10 0 0 ptg000008l:17689594-17689934 P35067 6.67e-73 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 33777 FUN_012958 0 0 0 0 6 NA NA NA NA NA NA NA 33778 FUN_009960 1727 1602 687 299 765 NA NA NA NA NA NA NA 33779 FUN_009961 3374 2175 1612 2676 2308 NA NA NA NA NA NA NA 33780 FUN_009962 0 0 6 0 0 NA NA NA NA NA NA NA 33781 FUN_009966 50 0 29 0 25 NA NA NA NA NA NA NA 33782 FUN_032306 179 43 40 83 43 NA NA NA NA NA NA NA 33783 FUN_032307 3760 1734 1245 2374 2147 NA NA NA NA NA NA NA 33784 FUN_032304 5908 8008 4875 7003 5865 ptg000023l:30681313-30682567 Q99470 1.94e-24 Stromal cell-derived factor 2 (SDF-2) Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085] GO:0005783; GO:0051085; GO:0051787; GO:0101031 33785 FUN_032305 14021 9602 8535 13006 7091 NA NA NA NA NA NA NA 33786 FUN_032302 304 136 108 198 230 NA NA NA NA NA NA NA 33787 FUN_032303 604 451 392 533 669 NA NA NA NA NA NA NA 33788 FUN_032300 1348 1197 885 1201 1096 NA NA NA NA NA NA NA 33789 FUN_032301 1493 2201 1387 1342 1101 ptg000023l:30674969-30676628 O55091 9.02e-52 Protein IMPACT (Imprinted and ancient gene protein) Mus musculus (Mouse) cellular response to acidic pH [GO:0071468]; cellular response to amino acid starvation [GO:0034198]; cellular response to benomyl [GO:0072755]; cellular response to glucose starvation [GO:0042149]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to leucine starvation [GO:1990253]; cellular response to UV-C [GO:0071494]; GCN2-mediated signaling [GO:0140469]; negative regulation of cell death [GO:0060548]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of transcription from RNA polymerase II promoter in response to stress [GO:0097201]; neuron projection extension [GO:1990138]; positive regulation of neuron differentiation [GO:0045666]; positive regulation of translational initiation in response to starvation [GO:0071264]; regulation of translational initiation [GO:0006446] GO:0000122; GO:0001933; GO:0003779; GO:0005829; GO:0005844; GO:0006446; GO:0031333; GO:0031953; GO:0034198; GO:0042149; GO:0043022; GO:0045666; GO:0060548; GO:0070301; GO:0071264; GO:0071468; GO:0071494; GO:0072755; GO:0097201; GO:0140469; GO:1990138; GO:1990253 33790 FUN_032308 4432 3910 2241 5448 5033 NA NA NA NA NA NA NA 33791 FUN_032309 2939 4233 2302 2679 1569 NA NA NA NA NA NA NA 33792 FUN_015040 0 32 136 83 77 NA NA NA NA NA NA NA 33793 FUN_011217 0 0 0 0 7 NA NA NA NA NA NA NA 33794 FUN_011215 0 0 12 3 173 NA NA NA NA NA NA NA 33795 FUN_011214 2 0 17 10 67 NA NA NA NA NA NA NA 33796 FUN_000372 2061 2054 1045 735 122 NA NA NA NA NA NA NA 33797 FUN_000373 374 291 253 422 253 NA NA NA NA NA NA NA 33798 FUN_000370 6308 6353 3459 4233 3351 ntLink_6:2145305-2149657 Q5R4A3 5.3e-25 Ras-related protein Rab-8A (EC 3.6.5.2) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) autophagy [GO:0006914]; axonogenesis [GO:0007409]; cellular response to insulin stimulus [GO:0032869]; cilium assembly [GO:0060271]; Golgi organization [GO:0007030]; protein localization to cilium [GO:0061512]; protein localization to plasma membrane [GO:0072659]; protein transport [GO:0015031]; regulation of autophagy [GO:0010506] GO:0003924; GO:0005525; GO:0005794; GO:0005813; GO:0005814; GO:0005886; GO:0005929; GO:0006914; GO:0007030; GO:0007409; GO:0010506; GO:0015031; GO:0019003; GO:0030496; GO:0030670; GO:0031267; GO:0032869; GO:0036064; GO:0045335; GO:0055038; GO:0060271; GO:0061512; GO:0072659 33799 FUN_000376 753 310 296 755 1518 NA NA NA NA NA NA NA 33800 FUN_000374 390 129 160 245 227 ntLink_6:2185843-2199020 O43345 1.33e-41 Zinc finger protein 208 (Zinc finger protein 91-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0008270 33801 FUN_000374 390 129 160 245 227 ntLink_6:2185843-2199020 O43345 1.59e-37 Zinc finger protein 208 (Zinc finger protein 91-like) Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0001228; GO:0005634; GO:0006357; GO:0008270 33802 FUN_000375 234 109 153 85 116 NA NA NA NA NA NA NA 33803 FUN_008619 11471 7897 5727 9553 6126 NA NA NA NA NA NA NA 33804 FUN_008618 36 115 87 125 134 NA NA NA NA NA NA NA 33805 FUN_008611 0 0 46 25 25 NA NA NA NA NA NA NA 33806 FUN_008610 3882 2686 2290 4042 3956 ptg000002l:13553650-13569386 Q9I8E6 5.52e-22 Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP) Takifugu rubripes (Japanese pufferfish) (Fugu rubripes) intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GO:0000139; GO:0005198; GO:0006886; GO:0016192; GO:0030126 33807 FUN_008613 25 18 78 7 0 NA NA NA NA NA NA NA 33808 FUN_008612 154 246 40 96 29 NA NA NA NA NA NA NA 33809 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 1.2e-128 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33810 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 1.37e-88 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33811 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 3.33e-76 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33812 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 1.18e-68 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33813 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 1.8e-57 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33814 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 2.01e-37 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33815 FUN_008615 3675 1875 2076 4058 3343 ptg000002l:13610980-13641839 Q91ZI0 1.54e-23 Cadherin EGF LAG seven-pass G-type receptor 3 Mus musculus (Mouse) axonal fasciculation [GO:0007413]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; dopaminergic neuron axon guidance [GO:0036514]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; planar cell polarity pathway involved in axon guidance [GO:1904938]; regulation of protein localization [GO:0032880]; regulation of protein phosphorylation [GO:0001932]; serotonergic neuron axon guidance [GO:0036515] GO:0001932; GO:0004930; GO:0005509; GO:0005886; GO:0007156; GO:0007413; GO:0032880; GO:0036514; GO:0036515; GO:0060271; GO:0097475; GO:0098609; GO:1904938 33816 FUN_008614 2045 1461 1144 1719 1720 NA NA NA NA NA NA NA 33817 FUN_008617 235 251 176 310 432 ptg000002l:13675438-13682105 Q5XTS1 3.41e-24 Calcium-independent phospholipase A2-gamma (EC 3.1.1.-) (EC 3.1.1.5) (Group VIB calcium-independent phospholipase A2) (Intracellular membrane-associated calcium-independent phospholipase A2 gamma) (iPLA2-gamma) (Patatin-like phospholipase domain-containing protein 8) Oryctolagus cuniculus (Rabbit) arachidonic acid metabolic process [GO:0019369]; cardiolipin metabolic process [GO:0032048]; lipid catabolic process [GO:0016042]; lipid homeostasis [GO:0055088]; triglyceride homeostasis [GO:0070328] GO:0004622; GO:0005739; GO:0005777; GO:0005778; GO:0005789; GO:0008970; GO:0016020; GO:0016042; GO:0019369; GO:0031966; GO:0032048; GO:0047499; GO:0055088; GO:0070328; GO:0102545 33818 FUN_008616 2707 476 497 1392 1116 ptg000002l:13654566-13673027 E7FDW2 1.81e-35 E3 ubiquitin-protein ligase PDZRN3-B (EC 2.3.2.27) (PDZ domain-containing RING finger protein 3-B) Danio rerio (Zebrafish) (Brachydanio rerio) neuromuscular junction development [GO:0007528]; protein ubiquitination [GO:0016567] GO:0005737; GO:0007528; GO:0016567; GO:0045202; GO:0046872; GO:0061630 33819 FUN_029048 34 2 19 17 12 NA NA NA NA NA NA NA 33820 FUN_029041 2692 1888 1386 2456 1965 NA NA NA NA NA NA NA 33821 FUN_029040 971 811 415 1038 668 ptg000022l:7546286-7554341 P17971 3.77e-153 Potassium voltage-gated channel protein Shal (Shaker cognate l) (Shal2) Drosophila melanogaster (Fruit fly) associative learning [GO:0008306]; chemical synaptic transmission [GO:0007268]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005250; GO:0005886; GO:0006813; GO:0007268; GO:0008076; GO:0008306; GO:0016020; GO:0030425; GO:0034765; GO:0043204; GO:0045202; GO:0051260; GO:0071805 33822 FUN_029043 91 290 474 426 524 NA NA NA NA NA NA NA 33823 FUN_029042 1758 1168 987 1600 1165 NA NA NA NA NA NA NA 33824 FUN_029045 8639 10960 4972 6587 5755 NA NA NA NA NA NA NA 33825 FUN_029044 9 0 25 4 100 NA NA NA NA NA NA NA 33826 FUN_017798 31 15 15 17 46 NA NA NA NA NA NA NA 33827 FUN_018567 12 0 0 0 4 NA NA NA NA NA NA NA 33828 FUN_039035 404 237 159 182 364 NA NA NA NA NA NA NA 33829 FUN_039037 463 461 140 529 785 NA NA NA NA NA NA NA 33830 FUN_039036 341 317 179 404 400 NA NA NA NA NA NA NA 33831 FUN_039030 0 0 20 22 15 ptg000027l:13933488-13935758 P12276 9.32e-58 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 33832 FUN_039032 0 0 14 0 13 ptg000027l:13945583-13957625 P12276 9.08e-131 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 33833 FUN_039032 0 0 14 0 13 ptg000027l:13945583-13957625 P12276 1.21e-93 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 33834 FUN_039032 0 0 14 0 13 ptg000027l:13945583-13957625 P12276 3.55e-36 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 33835 FUN_039032 0 0 14 0 13 ptg000027l:13945583-13957625 P12276 1.88e-34 Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)] Gallus gallus (Chicken) fatty acid biosynthetic process [GO:0006633]; lactate metabolic process [GO:0006089]; positive regulation of appetite [GO:0032100] GO:0003697; GO:0004312; GO:0004313; GO:0004314; GO:0004315; GO:0004316; GO:0004317; GO:0004320; GO:0005737; GO:0006089; GO:0006633; GO:0008659; GO:0008693; GO:0016295; GO:0016296; GO:0031177; GO:0032100; GO:0047117; GO:0047451 33836 FUN_017796 1112 595 581 761 836 NA NA NA NA NA NA NA 33837 FUN_029580 48 23 23 0 19 NA NA NA NA NA NA NA 33838 FUN_043370 725 253 194 753 484 NA NA NA NA NA NA NA 33839 FUN_012423 178 180 43 128 165 NA NA NA NA NA NA NA 33840 FUN_029583 30 2 0 5 5 NA NA NA NA NA NA NA 33841 FUN_012424 0 13 0 13 5 NA NA NA NA NA NA NA 33842 FUN_029586 1644 702 671 612 1194 ptg000023l:3522834-3531688 D2GXS7 1.35e-33 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) Ailuropoda melanoleuca (Giant panda) regulation of neuron apoptotic process [GO:0043523] GO:0004842; GO:0005737; GO:0008270; GO:0043523 33843 FUN_012426 0 0 0 17 0 NA NA NA NA NA NA NA 33844 FUN_012429 747 377 237 710 474 NA NA NA NA NA NA NA 33845 FUN_029589 141 12 22 0 110 ptg000023l:3545125-3547297 E7FAM5 4.16e-55 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 33846 FUN_010629 528 808 412 564 592 NA NA NA NA NA NA NA 33847 FUN_010628 871 187 303 429 424 NA NA NA NA NA NA NA 33848 FUN_010621 1488 1073 1123 1391 1641 ptg000007l:877951-891813 Q5ZIT8 4.69e-21 Transcription initiation factor TFIID subunit 2 (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150) Gallus gallus (Chicken) transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0000976; GO:0003682; GO:0005669; GO:0006367 33849 FUN_010620 871 845 845 2219 2200 NA NA NA NA NA NA NA 33850 FUN_010623 7504 7842 6376 13604 8558 ptg000007l:899395-906372 Q91VZ6 3.52e-29 Stromal membrane-associated protein 1 Mus musculus (Mouse) positive regulation of erythrocyte differentiation [GO:0045648]; regulation of clathrin-dependent endocytosis [GO:2000369] GO:0005096; GO:0005737; GO:0005886; GO:0030276; GO:0045648; GO:0046872; GO:2000369 33851 FUN_010623 7504 7842 6376 13604 8558 ptg000007l:899395-906372 Q91VZ6 3.52e-29 Stromal membrane-associated protein 1 Mus musculus (Mouse) positive regulation of erythrocyte differentiation [GO:0045648]; regulation of clathrin-dependent endocytosis [GO:2000369] GO:0005096; GO:0005737; GO:0005886; GO:0030276; GO:0045648; GO:0046872; GO:2000369 33852 FUN_010623 7504 7842 6376 13604 8558 ptg000007l:899395-906372 Q91VZ6 3.52e-29 Stromal membrane-associated protein 1 Mus musculus (Mouse) positive regulation of erythrocyte differentiation [GO:0045648]; regulation of clathrin-dependent endocytosis [GO:2000369] GO:0005096; GO:0005737; GO:0005886; GO:0030276; GO:0045648; GO:0046872; GO:2000369 33853 FUN_010622 710 774 549 827 435 NA NA NA NA NA NA NA 33854 FUN_010625 53 49 10 37 33 NA NA NA NA NA NA NA 33855 FUN_010624 3650 1996 1665 2606 2785 NA NA NA NA NA NA NA 33856 FUN_010627 811 421 349 462 593 ptg000007l:943317-944485 P70284 1.66e-33 Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1) Mus musculus (Mouse) amacrine cell differentiation [GO:0035881]; cell population proliferation [GO:0008283]; determination of left/right symmetry [GO:0007368]; dorsal/ventral pattern formation [GO:0009953]; fibroblast proliferation [GO:0048144]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of gene expression [GO:0010629]; negative regulation of retinoic acid receptor signaling pathway [GO:0048387]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; neuron differentiation [GO:0030182]; nodal signaling pathway [GO:0038092]; positive regulation of amacrine cell differentiation [GO:1902871]; positive regulation of fibroblast proliferation [GO:0048146]; regulation of gastrulation [GO:0010470]; regulation of transcription by RNA polymerase II [GO:0006357]; retina development in camera-type eye [GO:0060041] GO:0000122; GO:0000978; GO:0000981; GO:0001227; GO:0001843; GO:0003682; GO:0005634; GO:0005654; GO:0006357; GO:0007368; GO:0008283; GO:0008285; GO:0008432; GO:0009953; GO:0010470; GO:0010629; GO:0030182; GO:0035881; GO:0038092; GO:0048144; GO:0048146; GO:0048387; GO:0060041; GO:0070410; GO:1902871; GO:1990837 33857 FUN_010626 136 59 64 71 149 NA NA NA NA NA NA NA 33858 FUN_012173 35 87 79 110 109 NA NA NA NA NA NA NA 33859 FUN_012172 763 1068 1113 978 902 NA NA NA NA NA NA NA 33860 FUN_012171 3580 3997 1968 3045 2634 NA NA NA NA NA NA NA 33861 FUN_012170 3636 4752 2231 4230 3911 NA NA NA NA NA NA NA 33862 FUN_012177 19403 16866 10216 27285 15845 ptg000008l:6061486-6075999 P51812 5.14e-36 Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) Homo sapiens (Human) cell cycle [GO:0007049]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; intracellular signal transduction [GO:0035556]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of cell differentiation [GO:0045597]; positive regulation of cell growth [GO:0030307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of DNA-templated transcription in response to stress [GO:0043620]; regulation of translation in response to stress [GO:0043555]; response to lipopolysaccharide [GO:0032496]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; toll-like receptor signaling pathway [GO:0002224] GO:0000287; GO:0001501; GO:0002224; GO:0004672; GO:0004674; GO:0004711; GO:0005524; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0007049; GO:0007165; GO:0007268; GO:0007417; GO:0018105; GO:0019901; GO:0030307; GO:0032496; GO:0035556; GO:0043027; GO:0043066; GO:0043154; GO:0043555; GO:0043620; GO:0045202; GO:0045597; GO:0045944; GO:0106310 33863 FUN_012176 5535 4336 2374 6339 6767 NA NA NA NA NA NA NA 33864 FUN_012175 132 78 31 53 68 NA NA NA NA NA NA NA 33865 FUN_012174 88 318 45 261 74 NA NA NA NA NA NA NA 33866 FUN_012179 768 247 270 1029 552 NA NA NA NA NA NA NA 33867 FUN_012178 5486 3762 2087 4295 3191 ptg000008l:6082979-6095721 Q24572 6.34e-21 Chromatin assembly factor 1 p55 subunit (CAF-1 p55 subunit) (CAF-1) (Nucleosome-remodeling factor 55 kDa subunit) (NURF-55) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; chromatin remodeling [GO:0006338]; DNA replication-dependent chromatin assembly [GO:0006335]; eggshell chorion gene amplification [GO:0007307]; facultative heterochromatin formation [GO:0140718]; heterochromatin formation [GO:0031507]; histone deacetylation [GO:0016575]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nucleosome organization [GO:0034728]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of DNA-templated transcription [GO:0006355]; regulation of mitotic cell cycle [GO:0007346]; segment specification [GO:0007379] GO:0000122; GO:0000976; GO:0005634; GO:0005667; GO:0005700; GO:0006325; GO:0006335; GO:0006338; GO:0006355; GO:0007307; GO:0007346; GO:0007379; GO:0016575; GO:0016581; GO:0016589; GO:0031507; GO:0031523; GO:0033186; GO:0034728; GO:0035097; GO:0035098; GO:0042393; GO:0042803; GO:0042826; GO:0045892; GO:0045893; GO:0070822; GO:0140718 33868 FUN_020873 0 0 0 19 0 NA NA NA NA NA NA NA 33869 FUN_020872 17 0 12 19 15 NA NA NA NA NA NA NA 33870 FUN_020870 4 0 10 0 19 NA NA NA NA NA NA NA 33871 FUN_020877 0 0 0 0 20 NA NA NA NA NA NA NA 33872 FUN_020875 37 0 24 5 108 NA NA NA NA NA NA NA 33873 FUN_020874 0 0 0 7 0 NA NA NA NA NA NA NA 33874 FUN_003610 57 0 18 0 47 NA NA NA NA NA NA NA 33875 FUN_038849 4 0 0 0 50 NA NA NA NA NA NA NA 33876 FUN_038848 39 24 33 0 110 NA NA NA NA NA NA NA 33877 FUN_038841 2023 2450 2025 7092 849 NA NA NA NA NA NA NA 33878 FUN_038840 238 260 106 415 403 NA NA NA NA NA NA NA 33879 FUN_038845 1076 1448 306 909 768 NA NA NA NA NA NA NA 33880 FUN_003613 6 0 63 0 6 NA NA NA NA NA NA NA 33881 FUN_031643 3831 2855 1583 1995 2412 ptg000023l:23812858-23823669 Q28653 5.55e-29 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) Oryctolagus cuniculus (Rabbit) signal transduction [GO:0007165] GO:0000159; GO:0005634; GO:0007165; GO:0019888 33882 FUN_031643 3831 2855 1583 1995 2412 ptg000023l:23812858-23823669 Q28653 1.72e-25 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) Oryctolagus cuniculus (Rabbit) signal transduction [GO:0007165] GO:0000159; GO:0005634; GO:0007165; GO:0019888 33883 FUN_031643 3831 2855 1583 1995 2412 ptg000023l:23812858-23823669 Q28653 1.72e-25 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-gamma) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) Oryctolagus cuniculus (Rabbit) signal transduction [GO:0007165] GO:0000159; GO:0005634; GO:0007165; GO:0019888 33884 FUN_003614 0 0 115 5 0 NA NA NA NA NA NA NA 33885 FUN_036612 15 0 39 0 120 NA NA NA NA NA NA NA 33886 FUN_004647 19 0 0 8 0 ntLink_8:25345250-25346146 Q90415 3.89e-26 Retinoic acid receptor RXR-alpha-B (Nuclear receptor subfamily 2 group B member 1-B) (Retinoid X receptor alpha-B) Danio rerio (Zebrafish) (Brachydanio rerio) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; response to retinoic acid [GO:0032526]; retinoic acid receptor signaling pathway [GO:0048384] GO:0000122; GO:0000978; GO:0003700; GO:0003707; GO:0004879; GO:0006357; GO:0008270; GO:0030154; GO:0032526; GO:0044323; GO:0045944; GO:0048384; GO:0048856; GO:0090575 33887 FUN_031641 893 726 533 842 798 NA NA NA NA NA NA NA 33888 FUN_003616 0 0 23 0 0 NA NA NA NA NA NA NA 33889 FUN_031644 1947 632 797 1044 523 ptg000023l:23828864-23832438 Q3EBF7 1.47e-84 Delta(8)-fatty-acid desaturase 2 (EC 1.14.19.29) (Delta(8)-sphingolipid desaturase 2) (Sphingoid long-chain base desaturase 2) (Sphingoid LCB desaturase 2) (Sphingolipid 8-(E/Z)-desaturase 2) Arabidopsis thaliana (Mouse-ear cress) cellular response to cold [GO:0070417]; lipid metabolic process [GO:0006629]; sphingolipid biosynthetic process [GO:0030148] GO:0005783; GO:0005789; GO:0006629; GO:0016717; GO:0030148; GO:0046872; GO:0052631; GO:0070417 33890 FUN_040046 214 459 154 389 228 NA NA NA NA NA NA NA 33891 FUN_040040 235 96 169 211 395 ptg000031l:3399492-3401411 Q9BRS2 2.57e-174 Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1) Homo sapiens (Human) maturation of SSU-rRNA [GO:0030490]; phosphorylation [GO:0016310]; positive regulation of rRNA processing [GO:2000234]; ribosomal small subunit biogenesis [GO:0042274] GO:0004674; GO:0005524; GO:0005654; GO:0005829; GO:0016310; GO:0016787; GO:0030490; GO:0030688; GO:0034708; GO:0042274; GO:0046872; GO:0106310; GO:2000234 33892 FUN_023010 1697 2330 834 2311 1879 ptg000017l:2623888-2627540 Q5H9S7 2.95e-60 DDB1- and CUL4-associated factor 17 Homo sapiens (Human) protein ubiquitination [GO:0016567] GO:0005654; GO:0005730; GO:0005829; GO:0016020; GO:0016567; GO:0080008 33893 FUN_040041 731 724 684 1186 1149 NA NA NA NA NA NA NA 33894 FUN_014636 1787 1233 377 751 789 NA NA NA NA NA NA NA 33895 FUN_014637 5827 5389 4629 6046 5256 ptg000009l:1760101-1764910 Q07417 4.15e-46 Short-chain specific acyl-CoA dehydrogenase, mitochondrial (SCAD) (EC 1.3.8.1) (Butyryl-CoA dehydrogenase) Mus musculus (Mouse) butyrate catabolic process [GO:0046359]; fatty acid beta-oxidation using acyl-CoA dehydrogenase [GO:0033539] GO:0000062; GO:0003995; GO:0004085; GO:0005654; GO:0005739; GO:0005759; GO:0005813; GO:0016937; GO:0031966; GO:0033539; GO:0042802; GO:0046359; GO:0050660 33896 FUN_014635 10 0 4 0 32 NA NA NA NA NA NA NA 33897 FUN_014632 1456 1713 1104 1435 1324 ptg000009l:1703805-1705596 Q5ZKR4 1.46e-67 Rab-like protein 3 Gallus gallus (Chicken) B cell differentiation [GO:0030183]; intracellular protein transport [GO:0006886]; natural killer cell differentiation [GO:0001779]; regulation of protein lipidation [GO:1903059]; regulation of Ras protein signal transduction [GO:0046578]; T cell differentiation in thymus [GO:0033077] GO:0001779; GO:0003924; GO:0005525; GO:0006886; GO:0012505; GO:0030183; GO:0033077; GO:0042803; GO:0046578; GO:1903059 33898 FUN_040042 1803 4376 1912 2438 685 ptg000031l:3438943-3443053 Q66IM1 4.14e-29 Sigma non-opioid intracellular receptor 1 (Sigma 1-type opioid receptor) (Sigma1-receptor) (Sigma1R) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) lipid transport [GO:0006869] GO:0005637; GO:0005640; GO:0005789; GO:0006869; GO:0016020; GO:0031410 33899 FUN_014630 2418 1361 1048 831 771 NA NA NA NA NA NA NA 33900 FUN_014631 218 82 118 135 223 ptg000009l:1702354-1703657 Q99J99 7.54e-47 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) Mus musculus (Mouse) hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346] GO:0001822; GO:0001889; GO:0004792; GO:0005737; GO:0005739; GO:0005743; GO:0005829; GO:0016784; GO:0019346; GO:0021510; GO:0042802; GO:0043005; GO:0045202; GO:0070814 33901 FUN_014631 218 82 118 135 223 ptg000009l:1702354-1703657 Q99J99 2.71e-36 3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2) Mus musculus (Mouse) hydrogen sulfide biosynthetic process [GO:0070814]; kidney development [GO:0001822]; liver development [GO:0001889]; spinal cord development [GO:0021510]; transsulfuration [GO:0019346] GO:0001822; GO:0001889; GO:0004792; GO:0005737; GO:0005739; GO:0005743; GO:0005829; GO:0016784; GO:0019346; GO:0021510; GO:0042802; GO:0043005; GO:0045202; GO:0070814 33902 FUN_040043 2204 2310 1523 2361 1227 NA NA NA NA NA NA NA 33903 FUN_014638 740 436 349 320 359 NA NA NA NA NA NA NA 33904 FUN_014639 2711 3188 2189 2534 1893 NA NA NA NA NA NA NA 33905 FUN_010187 0 0 0 0 11 NA NA NA NA NA NA NA 33906 FUN_040049 44 96 83 130 57 NA NA NA NA NA NA NA 33907 FUN_025962 0 7 5 23 0 NA NA NA NA NA NA NA 33908 FUN_009572 10 0 54 3 30 NA NA NA NA NA NA NA 33909 FUN_009571 371 0 148 0 257 NA NA NA NA NA NA NA 33910 FUN_009576 33 41 6 54 14 NA NA NA NA NA NA NA 33911 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 6.59e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33912 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.48e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33913 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 5.45e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33914 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 4.2e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33915 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 7.96e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33916 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 8.31e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33917 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.23e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33918 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.58e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33919 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.13e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33920 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.05e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33921 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.23e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33922 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 3.54e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33923 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 5.81e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33924 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 1.1e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33925 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 5.03e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33926 FUN_009574 2449 8 2502 33 0 ptg000004l:8732680-8740325 Q96AY4 8.91e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33927 FUN_009579 50 0 64 15 22 NA NA NA NA NA NA NA 33928 FUN_025969 0 8 4 0 33 NA NA NA NA NA NA NA 33929 FUN_026703 239 391 119 170 148 NA NA NA NA NA NA NA 33930 FUN_026700 7 123 5 19 2 NA NA NA NA NA NA NA 33931 FUN_026705 236 156 92 187 46 ptg000020l:12686446-12689227 Q8CBH5 2.08e-33 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2) Mus musculus (Mouse) adaptive immune response [GO:0002250]; antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0002250; GO:0005886; GO:0016020; GO:0032393; GO:0042288; GO:0042590 33932 FUN_026704 451 339 152 361 408 NA NA NA NA NA NA NA 33933 FUN_026709 684 358 283 374 305 ptg000020l:12716752-12718459 A1DWM3 1.91e-30 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 33934 FUN_026708 2394 1282 1199 1880 1420 NA NA NA NA NA NA NA 33935 FUN_022467 5296 7110 1833 4738 4508 NA NA NA NA NA NA NA 33936 FUN_022464 0 0 0 0 16 NA NA NA NA NA NA NA 33937 FUN_022465 1001 605 129 332 216 NA NA NA NA NA NA NA 33938 FUN_022468 164 92 17 28 73 NA NA NA NA NA NA NA 33939 FUN_022469 300 90 51 128 133 NA NA NA NA NA NA NA 33940 FUN_024705 21 0 14 31 92 NA NA NA NA NA NA NA 33941 FUN_024704 0 0 5 6 38 NA NA NA NA NA NA NA 33942 FUN_024706 178 337 21 38 93 ptg000018l:10117596-10129098 E7FAM5 9.07e-47 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 33943 FUN_024701 69 14 0 54 109 NA NA NA NA NA NA NA 33944 FUN_024700 30 0 77 13 298 NA NA NA NA NA NA NA 33945 FUN_024702 168 243 77 188 169 NA NA NA NA NA NA NA 33946 FUN_024709 66 22 67 96 63 ptg000018l:10158275-10160847 F6QEU4 2.59e-48 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; neural tube development [GO:0021915]; protein autoubiquitination [GO:0051865]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0021915; GO:0035198; GO:0035278; GO:0051865; GO:0060964; GO:0072089; GO:2000177 33947 FUN_030184 140 128 191 208 181 ptg000023l:10153225-10154635 O64411 9.06e-107 Polyamine oxidase 1 (EC 1.5.3.14) (EC 1.5.3.15) Zea mays (Maize) polyamine catabolic process [GO:0006598]; spermine catabolic process [GO:0046208] GO:0006598; GO:0009505; GO:0016491; GO:0046208; GO:0046592; GO:0048046; GO:0050660; GO:0052893; GO:0052896; GO:0052897; GO:0052900 33948 FUN_030185 0 0 0 17 11 NA NA NA NA NA NA NA 33949 FUN_035350 645 306 451 823 675 NA NA NA NA NA NA NA 33950 FUN_030183 1461 796 829 1269 1113 NA NA NA NA NA NA NA 33951 FUN_035352 76 54 40 64 14 ptg000025l:6639983-6641417 E1BD59 4.97e-23 E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (Tripartite motif-containing protein 56) Bos taurus (Bovine) defense response to virus [GO:0051607]; innate immune response [GO:0045087]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of interferon-beta production [GO:0032728]; protein K63-linked ubiquitination [GO:0070534]; response to type I interferon [GO:0034340] GO:0000785; GO:0004842; GO:0005654; GO:0005737; GO:0008270; GO:0032728; GO:0034340; GO:0045087; GO:0045893; GO:0051607; GO:0061630; GO:0070534 33952 FUN_035353 3169 205 731 137 1706 ptg000025l:6644765-6655709 Q4J9D2 1.44e-34 Uncharacterized protein Saci_1252 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) NA NA 33953 FUN_018632 0 0 9 3 0 ptg000012l:11391313-11410057 Q96AY4 1.15e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33954 FUN_018632 0 0 9 3 0 ptg000012l:11391313-11410057 Q96AY4 9.2e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33955 FUN_018632 0 0 9 3 0 ptg000012l:11391313-11410057 Q96AY4 7.11e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33956 FUN_018632 0 0 9 3 0 ptg000012l:11391313-11410057 Q96AY4 3.06e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33957 FUN_018632 0 0 9 3 0 ptg000012l:11391313-11410057 Q96AY4 2.22e-133 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 33958 FUN_018631 121 50 37 95 10 NA NA NA NA NA NA NA 33959 FUN_018634 0 0 0 7 0 NA NA NA NA NA NA NA 33960 FUN_019581 0 0 0 0 18 NA NA NA NA NA NA NA 33961 FUN_019587 5 0 0 0 51 NA NA NA NA NA NA NA 33962 FUN_019585 0 0 0 0 10 NA NA NA NA NA NA NA 33963 FUN_019589 14 0 7 0 0 NA NA NA NA NA NA NA 33964 FUN_019588 0 0 0 0 31 NA NA NA NA NA NA NA 33965 FUN_018982 0 0 18 79 193 NA NA NA NA NA NA NA 33966 FUN_018983 0 0 5 74 0 NA NA NA NA NA NA NA 33967 FUN_018989 0 0 0 0 18 NA NA NA NA NA NA NA 33968 FUN_035264 1843 897 993 1841 937 ptg000025l:5797462-5803071 Q16698 1.53e-23 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1) Homo sapiens (Human) fatty acid beta-oxidation [GO:0006635]; positive regulation of cold-induced thermogenesis [GO:0120162] GO:0005634; GO:0005654; GO:0005739; GO:0005759; GO:0005829; GO:0006635; GO:0008670; GO:0042802; GO:0070402; GO:0120162; GO:1902494 33969 FUN_035265 1019 1337 758 1676 1193 ptg000025l:5803404-5808818 F6R2G2 9.14e-22 NLR family CARD domain-containing protein 4 (Ice protease-activating factor) (Ipaf) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) apoptotic process [GO:0006915]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; regulation of apoptotic process [GO:0042981] GO:0005524; GO:0005829; GO:0006915; GO:0006954; GO:0042981; GO:0045087 33970 FUN_035266 432 243 228 260 404 NA NA NA NA NA NA NA 33971 FUN_028184 1101 2370 1339 585 1156 NA NA NA NA NA NA NA 33972 FUN_035260 4766 3851 2914 5292 4152 NA NA NA NA NA NA NA 33973 FUN_035261 160 254 93 301 283 NA NA NA NA NA NA NA 33974 FUN_035262 2284 2109 1240 2117 791 NA NA NA NA NA NA NA 33975 FUN_035263 7948 4336 3382 6691 6662 NA NA NA NA NA NA NA 33976 FUN_035268 8126 6761 3708 5226 3240 NA NA NA NA NA NA NA 33977 FUN_035269 652 604 552 469 851 NA NA NA NA NA NA NA 33978 FUN_038025 109 60 63 87 50 NA NA NA NA NA NA NA 33979 FUN_038024 7540 5178 3680 7466 6852 ptg000027l:1587292-1608150 Q09575 6.83e-45 Uncharacterized protein K02A2.6 Caenorhabditis elegans DNA integration [GO:0015074] GO:0003676; GO:0003887; GO:0005737; GO:0008270; GO:0015074; GO:0019899; GO:0042575 33980 FUN_038027 1508 929 826 818 632 NA NA NA NA NA NA NA 33981 FUN_038026 0 0 0 7 45 NA NA NA NA NA NA NA 33982 FUN_038021 84 97 66 86 58 ptg000027l:1571010-1573248 Q14314 1.28e-31 Fibroleukin (Fibrinogen-like protein 2) (pT49) Homo sapiens (Human) negative regulation of defense response to virus [GO:0050687]; negative regulation of dendritic cell antigen processing and presentation [GO:0002605]; negative regulation of macrophage antigen processing and presentation [GO:0002617]; negative regulation of memory T cell differentiation [GO:0043381]; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [GO:0002291] GO:0002291; GO:0002605; GO:0002617; GO:0005102; GO:0005576; GO:0005577; GO:0005615; GO:0043381; GO:0050687; GO:0062023; GO:0070062; GO:1904813 33983 FUN_038020 110 502 65 80 50 ptg000027l:1545757-1559331 O43827 1.36e-32 Angiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein) Homo sapiens (Human) negative regulation of vasculature development involved in avascular cornea development in camera-type eye [GO:1901346]; regulation of extracellular matrix organization [GO:1903053]; response to oxidative stress [GO:0006979] GO:0005102; GO:0005576; GO:0005615; GO:0006979; GO:0042802; GO:0062023; GO:1901346; GO:1903053 33984 FUN_038020 110 502 65 80 50 ptg000027l:1545757-1559331 O43827 8.6e-25 Angiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein) Homo sapiens (Human) negative regulation of vasculature development involved in avascular cornea development in camera-type eye [GO:1901346]; regulation of extracellular matrix organization [GO:1903053]; response to oxidative stress [GO:0006979] GO:0005102; GO:0005576; GO:0005615; GO:0006979; GO:0042802; GO:0062023; GO:1901346; GO:1903053 33985 FUN_038023 1484 1966 699 1074 770 ptg000027l:1582331-1583660 Q9QZS6 2.02e-98 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (m3-OST-3B) Mus musculus (Mouse) branching involved in ureteric bud morphogenesis [GO:0001658]; glycosaminoglycan biosynthetic process [GO:0006024]; heparan sulfate proteoglycan biosynthetic process [GO:0015012]; protein sulfation [GO:0006477] GO:0000139; GO:0001658; GO:0005886; GO:0006024; GO:0006477; GO:0008467; GO:0015012; GO:0033872 33986 FUN_038022 6 4 0 9 33 NA NA NA NA NA NA NA 33987 FUN_038029 23 0 46 46 29 NA NA NA NA NA NA NA 33988 FUN_038028 1540 1321 1452 1442 1570 NA NA NA NA NA NA NA 33989 FUN_036795 0 0 10 0 0 NA NA NA NA NA NA NA 33990 FUN_036794 0 1 27 7 36 NA NA NA NA NA NA NA 33991 FUN_036792 0 0 0 35 0 NA NA NA NA NA NA NA 33992 FUN_035793 0 9 0 0 0 NA NA NA NA NA NA NA 33993 FUN_039773 3170 1676 1323 2904 2702 NA NA NA NA NA NA NA 33994 FUN_039770 13 17 6 0 30 NA NA NA NA NA NA NA 33995 FUN_039771 0 0 0 0 28 NA NA NA NA NA NA NA 33996 FUN_039777 4232 3192 1571 2852 1484 NA NA NA NA NA NA NA 33997 FUN_039774 1247 909 565 1208 1509 NA NA NA NA NA NA NA 33998 FUN_039775 2705 2390 1356 2217 1401 NA NA NA NA NA NA NA 33999 FUN_007254 17 0 149 245 191 NA NA NA NA NA NA NA 34000 FUN_007256 0 0 2 5 13 NA NA NA NA NA NA NA 34001 FUN_007257 17 0 18 0 33 ptg000002l:583088-588507 Q6LAF1 1.04e-44 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34002 FUN_007259 36 1 29 0 41 NA NA NA NA NA NA NA 34003 FUN_030568 26 2 95 0 60 NA NA NA NA NA NA NA 34004 FUN_030569 106 8 53 4 425 NA NA NA NA NA NA NA 34005 FUN_030564 28 34 32 32 0 NA NA NA NA NA NA NA 34006 FUN_031219 0 0 0 6 0 ptg000023l:18124881-18132206 Q9R1I1 1.18e-24 Carbohydrate sulfotransferase 4 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3) (GST-3) (High endothelial cells N-acetylglucosamine 6-O-sulfotransferase) (HEC-GlcNAc6ST) (L-selectin ligand sulfotransferase) (LSST) (N-acetylglucosamine 6-O-sulfotransferase 2) (GlcNAc6ST-2) (Gn6st-2) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; inflammatory response [GO:0006954]; leukocyte tethering or rolling [GO:0050901]; N-acetylglucosamine metabolic process [GO:0006044]; positive regulation of leukocyte tethering or rolling [GO:1903238]; protein sulfation [GO:0006477]; sulfur compound metabolic process [GO:0006790] GO:0000139; GO:0001517; GO:0005802; GO:0005975; GO:0006044; GO:0006477; GO:0006790; GO:0006954; GO:0050901; GO:1903238 34007 FUN_031218 20 0 0 0 0 NA NA NA NA NA NA NA 34008 FUN_036249 493 535 319 463 368 NA NA NA NA NA NA NA 34009 FUN_036248 254 182 159 335 327 NA NA NA NA NA NA NA 34010 FUN_036247 903 607 474 470 483 NA NA NA NA NA NA NA 34011 FUN_036246 7796 7864 4590 7293 5757 ptg000025l:17039450-17057783 P08059 9.45e-28 Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Sus scrofa (Pig) erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin production [GO:0002639] GO:0001701; GO:0001707; GO:0002639; GO:0004347; GO:0005125; GO:0005615; GO:0005654; GO:0005829; GO:0006094; GO:0006096; GO:0010595; GO:0031625; GO:0034101; GO:0042593; GO:0048029; GO:0051156; GO:0060170; GO:0097367 34012 FUN_036246 7796 7864 4590 7293 5757 ptg000025l:17039450-17057783 P08059 9.45e-28 Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Sus scrofa (Pig) erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin production [GO:0002639] GO:0001701; GO:0001707; GO:0002639; GO:0004347; GO:0005125; GO:0005615; GO:0005654; GO:0005829; GO:0006094; GO:0006096; GO:0010595; GO:0031625; GO:0034101; GO:0042593; GO:0048029; GO:0051156; GO:0060170; GO:0097367 34013 FUN_036246 7796 7864 4590 7293 5757 ptg000025l:17039450-17057783 P08059 9.45e-28 Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Sus scrofa (Pig) erythrocyte homeostasis [GO:0034101]; gluconeogenesis [GO:0006094]; glucose 6-phosphate metabolic process [GO:0051156]; glucose homeostasis [GO:0042593]; glycolytic process [GO:0006096]; in utero embryonic development [GO:0001701]; mesoderm formation [GO:0001707]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of immunoglobulin production [GO:0002639] GO:0001701; GO:0001707; GO:0002639; GO:0004347; GO:0005125; GO:0005615; GO:0005654; GO:0005829; GO:0006094; GO:0006096; GO:0010595; GO:0031625; GO:0034101; GO:0042593; GO:0048029; GO:0051156; GO:0060170; GO:0097367 34014 FUN_031213 20 0 0 13 0 NA NA NA NA NA NA NA 34015 FUN_036244 163 104 92 226 320 ptg000025l:17006276-17029308 Q7YRU6 1.74e-21 Solute carrier family 12 member 7 (K-Cl cotransporter 4) (Potassium-chloride cotransporter isoform 4) Oryctolagus cuniculus (Rabbit) potassium ion transmembrane transport [GO:0071805] GO:0005886; GO:0015379; GO:0071805 34016 FUN_024550 0 18 0 37 0 NA NA NA NA NA NA NA 34017 FUN_027425 4 51 97 0 0 NA NA NA NA NA NA NA 34018 FUN_027424 9 0 34 0 0 NA NA NA NA NA NA NA 34019 FUN_027427 659 1746 833 6 107 NA NA NA NA NA NA NA 34020 FUN_026213 26 0 11 1 74 NA NA NA NA NA NA NA 34021 FUN_027423 0 0 0 0 20 NA NA NA NA NA NA NA 34022 FUN_027429 0 0 45 0 7 NA NA NA NA NA NA NA 34023 FUN_027428 1 0 0 0 10 NA NA NA NA NA NA NA 34024 FUN_024551 37 0 3 18 0 NA NA NA NA NA NA NA 34025 FUN_041296 494 239 150 582 330 NA NA NA NA NA NA NA 34026 FUN_023666 201 0 76 0 85 NA NA NA NA NA NA NA 34027 FUN_041294 13 74 2 33 8 NA NA NA NA NA NA NA 34028 FUN_023664 14 36 0 0 74 NA NA NA NA NA NA NA 34029 FUN_037118 900 36 56 332 211 ptg000026l:6028549-6033817 Q7Z494 1.12e-36 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 34030 FUN_037118 900 36 56 332 211 ptg000026l:6028549-6033817 Q7Z494 1.28e-33 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 34031 FUN_037118 900 36 56 332 211 ptg000026l:6028549-6033817 Q7Z494 4.65e-33 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 34032 FUN_037118 900 36 56 332 211 ptg000026l:6028549-6033817 Q7Z494 1.56e-27 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 34033 FUN_037118 900 36 56 332 211 ptg000026l:6028549-6033817 Q7Z494 1.56e-27 Nephrocystin-3 Homo sapiens (Human) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095; GO:2000167 34034 FUN_037114 3 0 28 122 43 ptg000026l:5980125-5983412 Q7TNH6 1.49e-34 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 34035 FUN_037114 3 0 28 122 43 ptg000026l:5980125-5983412 Q7TNH6 1.97e-28 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 34036 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 7.15e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34037 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 8.19e-50 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34038 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 5.7e-48 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34039 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 1.45e-46 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34040 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 1.89e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34041 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 2.59e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34042 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 3.73e-45 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34043 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 2.56e-43 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34044 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 1.75e-42 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34045 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 3.42e-40 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34046 FUN_037115 0 23 6 80 69 ptg000026l:5991613-6001127 P0CI65 5.25e-38 Nephrocystin-3 Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; convergent extension [GO:0060026]; determination of left/right symmetry [GO:0007368]; heart jogging [GO:0003146]; kidney development [GO:0001822]; Kupffer's vesicle development [GO:0070121]; left/right pattern formation [GO:0060972]; pronephros development [GO:0048793]; visual perception [GO:0007601]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0003146; GO:0005929; GO:0007368; GO:0007601; GO:0016055; GO:0048793; GO:0060026; GO:0060271; GO:0060972; GO:0070121; GO:0097543; GO:0097546 34047 FUN_037117 673 114 297 818 226 NA NA NA NA NA NA NA 34048 FUN_037110 39 0 27 12 22 NA NA NA NA NA NA NA 34049 FUN_037111 759 16 155 64 487 ptg000026l:5953992-5956905 Q7TNH6 5.71e-41 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 34050 FUN_037111 759 16 155 64 487 ptg000026l:5953992-5956905 Q7TNH6 5.88e-40 Nephrocystin-3 Mus musculus (Mouse) atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension [GO:0060026]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; establishment or maintenance of cell polarity [GO:0007163]; extracellular matrix organization [GO:0030198]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lipid metabolic process [GO:0006629]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; non-motile cilium assembly [GO:1905515]; photoreceptor cell maintenance [GO:0045494]; positive regulation of protein binding [GO:0032092]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005929; GO:0006629; GO:0007163; GO:0007368; GO:0016055; GO:0030198; GO:0030324; GO:0032092; GO:0035469; GO:0045494; GO:0048496; GO:0060026; GO:0060027; GO:0060271; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:0097543; GO:0097546; GO:1905515; GO:2000095 34051 FUN_037113 423 0 25 0 0 NA NA NA NA NA NA NA 34052 FUN_041290 19 13 6 19 9 NA NA NA NA NA NA NA 34053 FUN_006619 13608 21379 11697 24872 17876 ptg000001l:14750598-14767029 Q92598 2.91e-22 Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) Homo sapiens (Human) chaperone cofactor-dependent protein refolding [GO:0051085]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NK T cell activation [GO:0051135]; protein folding [GO:0006457]; response to unfolded protein [GO:0006986] GO:0000774; GO:0005524; GO:0005576; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005874; GO:0006457; GO:0006986; GO:0032991; GO:0043014; GO:0045345; GO:0051085; GO:0051135; GO:0070062; GO:0071682; GO:0140662 34054 FUN_006618 4 11 0 0 21 NA NA NA NA NA NA NA 34055 FUN_006617 207 301 69 60 244 NA NA NA NA NA NA NA 34056 FUN_006616 85 119 68 63 77 NA NA NA NA NA NA NA 34057 FUN_006615 51 27 23 21 180 NA NA NA NA NA NA NA 34058 FUN_041291 0 9 11 1 6 NA NA NA NA NA NA NA 34059 FUN_006613 217 153 125 150 154 NA NA NA NA NA NA NA 34060 FUN_006612 955 404 515 864 985 NA NA NA NA NA NA NA 34061 FUN_006611 732 1067 415 1329 742 NA NA NA NA NA NA NA 34062 FUN_006610 1026 277 178 617 436 NA NA NA NA NA NA NA 34063 FUN_032547 285 210 0 182 185 ptg000023l:33105304-33110486 Q96AY4 2.29e-180 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34064 FUN_032547 285 210 0 182 185 ptg000023l:33105304-33110486 Q96AY4 6.45e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34065 FUN_032547 285 210 0 182 185 ptg000023l:33105304-33110486 Q96AY4 2.19e-157 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34066 FUN_032547 285 210 0 182 185 ptg000023l:33105304-33110486 Q96AY4 3.05e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34067 FUN_032547 285 210 0 182 185 ptg000023l:33105304-33110486 Q96AY4 2.34e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34068 FUN_032547 285 210 0 182 185 ptg000023l:33105304-33110486 Q96AY4 1.35e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34069 FUN_032540 376 0 0 4121 0 NA NA NA NA NA NA NA 34070 FUN_005095 386 0 0 222 2 NA NA NA NA NA NA NA 34071 FUN_032542 369 520 462 871 1280 ptg000023l:33067520-33075723 Q6P4Y6 9.77e-26 Insulin receptor substrate 1 (IRS-1) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) insulin receptor signaling pathway [GO:0008286]; insulin-like growth factor receptor signaling pathway [GO:0048009] GO:0005158; GO:0005159; GO:0005634; GO:0005737; GO:0008286; GO:0042169; GO:0043231; GO:0043548; GO:0048009 34072 FUN_005098 18 0 0 23 0 NA NA NA NA NA NA NA 34073 FUN_005099 16 7 178 11 68 NA NA NA NA NA NA NA 34074 FUN_032549 305 41 169 124 177 ptg000023l:33118424-33119537 Q6P4F1 9.84e-24 Alpha-(1,3)-fucosyltransferase 10 (EC 2.4.1.-) (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) Homo sapiens (Human) cerebral cortex radially oriented cell migration [GO:0021799]; fertilization [GO:0009566]; fucosylation [GO:0036065]; hemopoiesis [GO:0030097]; L-fucose catabolic process [GO:0042355]; N-glycan fucosylation [GO:0036071]; nervous system development [GO:0007399]; neuroblast migration [GO:0097402]; neuronal stem cell division [GO:0036445]; neuronal stem cell population maintenance [GO:0097150]; oligosaccharide biosynthetic process [GO:0009312]; protein folding [GO:0006457]; protein glycosylation [GO:0006486]; protein targeting [GO:0006605]; wound healing [GO:0042060] GO:0000139; GO:0005654; GO:0005764; GO:0005783; GO:0005789; GO:0005794; GO:0006457; GO:0006486; GO:0006605; GO:0007399; GO:0008417; GO:0009312; GO:0009566; GO:0021799; GO:0030097; GO:0036065; GO:0036071; GO:0036445; GO:0042060; GO:0042355; GO:0046920; GO:0097150; GO:0097402 34075 FUN_003553 0 0 24 0 32 NA NA NA NA NA NA NA 34076 FUN_003552 0 74 6 0 43 NA NA NA NA NA NA NA 34077 FUN_003551 8 0 0 0 0 NA NA NA NA NA NA NA 34078 FUN_032898 0 0 20 14 32 NA NA NA NA NA NA NA 34079 FUN_032896 11 19 9 14 22 NA NA NA NA NA NA NA 34080 FUN_032897 0 0 32 0 13 NA NA NA NA NA NA NA 34081 FUN_032894 0 51 0 0 9 NA NA NA NA NA NA NA 34082 FUN_032895 403 999 885 315 193 NA NA NA NA NA NA NA 34083 FUN_032890 20 37 0 45 0 NA NA NA NA NA NA NA 34084 FUN_032891 0 0 8 21 62 NA NA NA NA NA NA NA 34085 FUN_026554 691 1091 462 932 676 NA NA NA NA NA NA NA 34086 FUN_002568 1 15 11 9 10 NA NA NA NA NA NA NA 34087 FUN_034490 16 0 0 0 17 NA NA NA NA NA NA NA 34088 FUN_026555 6342 10038 2562 9134 4956 NA NA NA NA NA NA NA 34089 FUN_024453 26345 34849 16520 23346 20286 ptg000018l:6544506-6547864 P51410 1.23e-27 60S ribosomal protein L9 Mus musculus (Mouse) cytoplasmic translation [GO:0002181]; translation [GO:0006412]; translation at postsynapse [GO:0140242]; translation at presynapse [GO:0140236] GO:0002181; GO:0003735; GO:0005737; GO:0005829; GO:0005840; GO:0006412; GO:0019843; GO:0022625; GO:0022626; GO:0045202; GO:0098793; GO:0098794; GO:0140236; GO:0140242 34090 FUN_041838 749 756 424 811 545 NA NA NA NA NA NA NA 34091 FUN_041839 2456 2357 1215 2242 1477 NA NA NA NA NA NA NA 34092 FUN_041836 2431 2354 1321 4013 1410 NA NA NA NA NA NA NA 34093 FUN_041837 3654 2112 1456 1867 2431 NA NA NA NA NA NA NA 34094 FUN_041834 4278 2158 1690 5135 3993 ptg000035l:8122573-8148764 B0R0T1 1.38e-34 von Willebrand factor A domain-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005737; GO:0005739; GO:0016887 34095 FUN_041834 4278 2158 1690 5135 3993 ptg000035l:8122573-8148764 B0R0T1 6.47e-31 von Willebrand factor A domain-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005737; GO:0005739; GO:0016887 34096 FUN_041834 4278 2158 1690 5135 3993 ptg000035l:8122573-8148764 B0R0T1 3.46e-21 von Willebrand factor A domain-containing protein 8 Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005737; GO:0005739; GO:0016887 34097 FUN_041835 24439 24615 16767 26336 14756 NA NA NA NA NA NA NA 34098 FUN_041832 128 51 36 306 32 NA NA NA NA NA NA NA 34099 FUN_041833 83 23 53 256 216 NA NA NA NA NA NA NA 34100 FUN_041830 0 0 11 1 22 NA NA NA NA NA NA NA 34101 FUN_041831 393 102 122 592 309 ptg000035l:8078039-8086728 Q9ER04 3.51e-52 Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005044; GO:0005886; GO:0006508; GO:0008233; GO:0043025 34102 FUN_041831 393 102 122 592 309 ptg000035l:8078039-8086728 Q9ER04 6.49e-52 Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005044; GO:0005886; GO:0006508; GO:0008233; GO:0043025 34103 FUN_041831 393 102 122 592 309 ptg000035l:8078039-8086728 Q9ER04 6.15e-39 Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005044; GO:0005886; GO:0006508; GO:0008233; GO:0043025 34104 FUN_041831 393 102 122 592 309 ptg000035l:8078039-8086728 Q9ER04 7.05e-21 Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin) Mus musculus (Mouse) proteolysis [GO:0006508] GO:0004252; GO:0005044; GO:0005886; GO:0006508; GO:0008233; GO:0043025 34105 FUN_026552 640 35 191 521 342 NA NA NA NA NA NA NA 34106 FUN_001348 47 136 107 118 79 NA NA NA NA NA NA NA 34107 FUN_001349 1233 1367 809 2320 1126 NA NA NA NA NA NA NA 34108 FUN_001344 4287 4018 1632 3662 2392 ntLink_6:11304543-11307451 P48734 1.96e-27 Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; epithelial cell differentiation [GO:0030855]; fibroblast proliferation [GO:0048144]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of protein localization to nucleus [GO:1900182]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000086; GO:0003682; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005759; GO:0005813; GO:0005829; GO:0005876; GO:0006468; GO:0006915; GO:0007095; GO:0008353; GO:0010971; GO:0018105; GO:0018107; GO:0030332; GO:0030496; GO:0030544; GO:0030855; GO:0034501; GO:0035173; GO:0042752; GO:0043066; GO:0048144; GO:0048511; GO:0051301; GO:0072686; GO:0090166; GO:0097125; GO:0106310; GO:1900182; GO:1905448 34109 FUN_001344 4287 4018 1632 3662 2392 ntLink_6:11304543-11307451 P48734 1.78e-24 Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; epithelial cell differentiation [GO:0030855]; fibroblast proliferation [GO:0048144]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of protein localization to nucleus [GO:1900182]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000086; GO:0003682; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005759; GO:0005813; GO:0005829; GO:0005876; GO:0006468; GO:0006915; GO:0007095; GO:0008353; GO:0010971; GO:0018105; GO:0018107; GO:0030332; GO:0030496; GO:0030544; GO:0030855; GO:0034501; GO:0035173; GO:0042752; GO:0043066; GO:0048144; GO:0048511; GO:0051301; GO:0072686; GO:0090166; GO:0097125; GO:0106310; GO:1900182; GO:1905448 34110 FUN_001344 4287 4018 1632 3662 2392 ntLink_6:11304543-11307451 P48734 1.1e-23 Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase) Bos taurus (Bovine) apoptotic process [GO:0006915]; cell division [GO:0051301]; epithelial cell differentiation [GO:0030855]; fibroblast proliferation [GO:0048144]; G2/M transition of mitotic cell cycle [GO:0000086]; Golgi disassembly [GO:0090166]; mitotic G2 DNA damage checkpoint signaling [GO:0007095]; negative regulation of apoptotic process [GO:0043066]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of mitochondrial ATP synthesis coupled electron transport [GO:1905448]; positive regulation of protein localization to nucleus [GO:1900182]; protein localization to kinetochore [GO:0034501]; protein phosphorylation [GO:0006468]; regulation of circadian rhythm [GO:0042752]; rhythmic process [GO:0048511] GO:0000086; GO:0003682; GO:0004674; GO:0004693; GO:0005524; GO:0005634; GO:0005654; GO:0005759; GO:0005813; GO:0005829; GO:0005876; GO:0006468; GO:0006915; GO:0007095; GO:0008353; GO:0010971; GO:0018105; GO:0018107; GO:0030332; GO:0030496; GO:0030544; GO:0030855; GO:0034501; GO:0035173; GO:0042752; GO:0043066; GO:0048144; GO:0048511; GO:0051301; GO:0072686; GO:0090166; GO:0097125; GO:0106310; GO:1900182; GO:1905448 34111 FUN_001345 282 192 182 246 217 NA NA NA NA NA NA NA 34112 FUN_001346 72 47 87 45 185 NA NA NA NA NA NA NA 34113 FUN_001347 3581 1644 1740 2063 2107 NA NA NA NA NA NA NA 34114 FUN_001340 1 0 4 12 147 NA NA NA NA NA NA NA 34115 FUN_001341 5092 4380 2408 3984 3245 NA NA NA NA NA NA NA 34116 FUN_001342 1700 1046 648 1392 1728 NA NA NA NA NA NA NA 34117 FUN_001343 4572 5725 2379 4042 2852 ntLink_6:11300576-11303345 B0K025 5.81e-30 Oligosaccharyltransferase complex subunit OSTC Rattus norvegicus (Rat) protein N-linked glycosylation [GO:0006487] GO:0006487; GO:0008250 34118 FUN_041245 0 3 9 0 21 NA NA NA NA NA NA NA 34119 FUN_002605 64 2 356 17 10 NA NA NA NA NA NA NA 34120 FUN_002606 618 328 1362 706 125 NA NA NA NA NA NA NA 34121 FUN_011113 3 41 7 16 44 NA NA NA NA NA NA NA 34122 FUN_011114 0 35 0 0 0 NA NA NA NA NA NA NA 34123 FUN_002602 47 48 50 212 17 NA NA NA NA NA NA NA 34124 FUN_011118 37 38 12 51 63 NA NA NA NA NA NA NA 34125 FUN_011119 0 90 39 130 52 NA NA NA NA NA NA NA 34126 FUN_041788 2346 1416 1051 2184 1458 NA NA NA NA NA NA NA 34127 FUN_012218 225 66 94 261 159 ptg000008l:6476232-6485633 Q008S8 2.25e-39 Epithelial cell-transforming sequence 2 oncogene-like (Lung-specific F-box and DH domain-containing protein) (Putative guanine nucleotide exchange factor LFDH) Homo sapiens (Human) NA GO:0005085 34128 FUN_041789 445 522 260 1250 489 NA NA NA NA NA NA NA 34129 FUN_004730 14 19 11 23 22 NA NA NA NA NA NA NA 34130 FUN_026551 158 82 91 80 94 NA NA NA NA NA NA NA 34131 FUN_011271 21 0 42 0 53 NA NA NA NA NA NA NA 34132 FUN_000359 1371 1083 403 483 561 NA NA NA NA NA NA NA 34133 FUN_041780 1845 1133 1135 2210 1701 NA NA NA NA NA NA NA 34134 FUN_024456 780 549 443 737 448 ptg000018l:6584800-6592204 A7S6A1 3.21e-80 FHIP family protein v1g243165 Nematostella vectensis (Starlet sea anemone) NA NA 34135 FUN_024456 780 549 443 737 448 ptg000018l:6584800-6592204 A7S6A1 2.96e-51 FHIP family protein v1g243165 Nematostella vectensis (Starlet sea anemone) NA NA 34136 FUN_024456 780 549 443 737 448 ptg000018l:6584800-6592204 A7S6A1 7.45e-33 FHIP family protein v1g243165 Nematostella vectensis (Starlet sea anemone) NA NA 34137 FUN_024456 780 549 443 737 448 ptg000018l:6584800-6592204 A7S6A1 1.07e-21 FHIP family protein v1g243165 Nematostella vectensis (Starlet sea anemone) NA NA 34138 FUN_041781 74 119 61 132 86 NA NA NA NA NA NA NA 34139 FUN_000356 1163 28 1219 2710 457 ntLink_6:1930287-1961594 P81274 4.22e-21 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 34140 FUN_000357 0 0 10 156 17 NA NA NA NA NA NA NA 34141 FUN_000350 14722 11212 5614 8903 7129 ntLink_6:1830684-1835747 P62494 1.26e-38 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 34142 FUN_000350 14722 11212 5614 8903 7129 ntLink_6:1830684-1835747 P62494 1.26e-38 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 34143 FUN_000350 14722 11212 5614 8903 7129 ntLink_6:1830684-1835747 P62494 9.1e-27 Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (24KG) Rattus norvegicus (Rat) amyloid-beta clearance by transcytosis [GO:0150093]; astral microtubule organization [GO:0030953]; establishment of protein localization to membrane [GO:0090150]; establishment of protein localization to organelle [GO:0072594]; establishment of vesicle localization [GO:0051650]; exocytosis [GO:0006887]; exosomal secretion [GO:1990182]; intracellular cholesterol transport [GO:0032367]; melanosome transport [GO:0032402]; mitotic metaphase plate congression [GO:0007080]; mitotic spindle assembly [GO:0090307]; multivesicular body assembly [GO:0036258]; neuron projection development [GO:0031175]; neurotransmitter receptor transport, endosome to postsynaptic membrane [GO:0098887]; positive regulation of axon extension [GO:0045773]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of G2/M transition of mitotic cell cycle [GO:0010971]; positive regulation of protein localization to plasma membrane [GO:1903078]; protein localization to cell surface [GO:0034394]; protein localization to plasma membrane [GO:0072659]; regulation of cytokinesis [GO:0032465]; regulation of long-term neuronal synaptic plasticity [GO:0048169]; regulation of multivesicular body size [GO:0010796]; regulation of protein transport [GO:0051223]; regulation of vesicle-mediated transport [GO:0060627]; vesicle-mediated transport [GO:0016192]; vesicle-mediated transport in synapse [GO:0099003] GO:0000922; GO:0003924; GO:0003925; GO:0005525; GO:0005737; GO:0005768; GO:0005771; GO:0005794; GO:0005802; GO:0005813; GO:0005814; GO:0005829; GO:0006887; GO:0007080; GO:0008017; GO:0010634; GO:0010796; GO:0010971; GO:0016020; GO:0016192; GO:0030133; GO:0030424; GO:0030953; GO:0031175; GO:0031410; GO:0031489; GO:0031982; GO:0032154; GO:0032367; GO:0032402; GO:0032465; GO:0032991; GO:0034394; GO:0036258; GO:0045335; GO:0045773; GO:0048169; GO:0048471; GO:0051223; GO:0051650; GO:0055037; GO:0055038; GO:0060627; GO:0070062; GO:0072594; GO:0072659; GO:0090150; GO:0090307; GO:0098685; GO:0098837; GO:0098887; GO:0098978; GO:0099003; GO:0150093; GO:1903078; GO:1990182 34144 FUN_041785 2046 1006 1198 2175 1129 NA NA NA NA NA NA NA 34145 FUN_012771 5037 4109 1713 3244 1806 ptg000008l:12622631-12627165 P21580 2.63e-38 Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37] Homo sapiens (Human) apoptotic process [GO:0006915]; B-1 B cell homeostasis [GO:0001922]; cell migration [GO:0016477]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cytoskeleton organization [GO:0007010]; establishment of protein localization to vacuole [GO:0072666]; inflammatory response [GO:0006954]; negative regulation of B cell activation [GO:0050869]; negative regulation of bone resorption [GO:0045779]; negative regulation of CD40 signaling pathway [GO:2000349]; negative regulation of chronic inflammatory response [GO:0002677]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway [GO:0070429]; negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070433]; negative regulation of osteoclast proliferation [GO:0090291]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of smooth muscle cell proliferation [GO:0048662]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 3 signaling pathway [GO:0034140]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; negative regulation of toll-like receptor 5 signaling pathway [GO:0034148]; negative regulation of tumor necrosis factor production [GO:0032720]; nucleotide-binding oligomerization domain containing signaling pathway [GO:0070423]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of protein catabolic process [GO:0045732]; positive regulation of Wnt signaling pathway [GO:0030177]; protein deubiquitination [GO:0016579]; protein deubiquitination involved in ubiquitin-dependent protein catabolic process [GO:0071947]; protein K11-linked deubiquitination [GO:0035871]; protein K29-linked deubiquitination [GO:0035523]; protein K33-linked deubiquitination [GO:1990168]; protein K48-linked deubiquitination [GO:0071108]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked deubiquitination [GO:0070536]; regulation of defense response to virus by host [GO:0050691]; regulation of germinal center formation [GO:0002634]; regulation of tumor necrosis factor-mediated signaling pathway [GO:0010803]; regulation of vascular wound healing [GO:0061043]; response to molecule of bacterial origin [GO:0002237]; response to muramyl dipeptide [GO:0032495]; tolerance induction to lipopolysaccharide [GO:0072573] GO:0001922; GO:0002020; GO:0002237; GO:0002634; GO:0002677; GO:0003677; GO:0004842; GO:0004843; GO:0005634; GO:0005737; GO:0005764; GO:0005829; GO:0006915; GO:0006954; GO:0007010; GO:0008022; GO:0008270; GO:0010803; GO:0016477; GO:0016579; GO:0019900; GO:0030177; GO:0031397; GO:0032088; GO:0032495; GO:0032691; GO:0032703; GO:0032715; GO:0032720; GO:0034136; GO:0034140; GO:0034144; GO:0034148; GO:0035523; GO:0035871; GO:0042802; GO:0043124; GO:0043130; GO:0043621; GO:0045732; GO:0045736; GO:0045779; GO:0045824; GO:0048662; GO:0050691; GO:0050728; GO:0050869; GO:0061043; GO:0061578; GO:0070062; GO:0070301; GO:0070423; GO:0070429; GO:0070433; GO:0070530; GO:0070536; GO:0070936; GO:0071108; GO:0071222; GO:0071947; GO:0072573; GO:0072666; GO:0090291; GO:1902042; GO:1990168; GO:2000347; GO:2000349; GO:2000352 34146 FUN_012770 2858 2042 1632 2081 1784 NA NA NA NA NA NA NA 34147 FUN_029472 436 124 60 275 129 NA NA NA NA NA NA NA 34148 FUN_029473 586 262 189 419 263 NA NA NA NA NA NA NA 34149 FUN_029474 95 38 133 91 178 NA NA NA NA NA NA NA 34150 FUN_012774 2070 1460 1044 1093 1049 NA NA NA NA NA NA NA 34151 FUN_029476 0 0 0 0 34 NA NA NA NA NA NA NA 34152 FUN_012776 294 302 87 307 137 NA NA NA NA NA NA NA 34153 FUN_012779 1965 1996 2611 2587 1784 NA NA NA NA NA NA NA 34154 FUN_029479 104 35 74 129 183 NA NA NA NA NA NA NA 34155 FUN_041787 677 1076 491 438 488 NA NA NA NA NA NA NA 34156 FUN_016461 1976 931 829 1095 957 ptg000011l:3324128-3325760 B3DIG4 0 NA NA NA NA 34157 FUN_016463 4724 4097 4073 8325 9603 ptg000011l:3423029-3429770 Q9EPR4 2.89e-64 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) (SVCT-2) (mSVCT2) (Yolk sac permease-like molecule 2) Mus musculus (Mouse) cellular response to ethanol [GO:0071361]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; negative regulation of neuron death [GO:1901215]; positive regulation of dendrite extension [GO:1903861]; response to oxidative stress [GO:0006979] GO:0005737; GO:0005886; GO:0006979; GO:0008520; GO:0009925; GO:0015229; GO:0015882; GO:0016323; GO:0016324; GO:0019852; GO:0071361; GO:1901215; GO:1903861 34158 FUN_016463 4724 4097 4073 8325 9603 ptg000011l:3423029-3429770 Q9EPR4 2.89e-64 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) (SVCT-2) (mSVCT2) (Yolk sac permease-like molecule 2) Mus musculus (Mouse) cellular response to ethanol [GO:0071361]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; negative regulation of neuron death [GO:1901215]; positive regulation of dendrite extension [GO:1903861]; response to oxidative stress [GO:0006979] GO:0005737; GO:0005886; GO:0006979; GO:0008520; GO:0009925; GO:0015229; GO:0015882; GO:0016323; GO:0016324; GO:0019852; GO:0071361; GO:1901215; GO:1903861 34159 FUN_016463 4724 4097 4073 8325 9603 ptg000011l:3423029-3429770 Q9EPR4 2.89e-64 Solute carrier family 23 member 2 (Na(+)/L-ascorbic acid transporter 2) (Sodium-dependent vitamin C transporter 2) (SVCT-2) (mSVCT2) (Yolk sac permease-like molecule 2) Mus musculus (Mouse) cellular response to ethanol [GO:0071361]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; negative regulation of neuron death [GO:1901215]; positive regulation of dendrite extension [GO:1903861]; response to oxidative stress [GO:0006979] GO:0005737; GO:0005886; GO:0006979; GO:0008520; GO:0009925; GO:0015229; GO:0015882; GO:0016323; GO:0016324; GO:0019852; GO:0071361; GO:1901215; GO:1903861 34160 FUN_016462 1401 1152 584 975 1005 ptg000011l:3412219-3417881 Q8CGQ8 5.01e-25 Sodium/potassium/calcium exchanger 4 (Na(+)/K(+)/Ca(2+)-exchange protein 4) (Solute carrier family 24 member 4) Mus musculus (Mouse) amelogenesis [GO:0097186]; calcium ion export across plasma membrane [GO:1990034]; calcium ion homeostasis [GO:0055074]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cellular calcium ion homeostasis [GO:0006874]; cellular response to high light intensity [GO:0071486]; cone photoresponse recovery [GO:0036368]; detection of chemical stimulus involved in sensory perception of smell [GO:0050911]; drinking behavior [GO:0042756]; membrane repolarization [GO:0086009]; negative regulation of calcium-mediated signaling [GO:0050849]; olfactory nerve maturation [GO:0021630]; phototransduction [GO:0007602]; positive regulation of gene expression [GO:0010628]; potassium ion transmembrane transport [GO:0071805]; regulation of eating behavior [GO:1903998]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of signaling receptor activity [GO:0010469]; response to melanocyte-stimulating hormone [GO:1990680]; response to odorant [GO:1990834]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725] GO:0005262; GO:0005432; GO:0005516; GO:0005737; GO:0005886; GO:0006874; GO:0007602; GO:0007608; GO:0008273; GO:0008277; GO:0010469; GO:0010628; GO:0015293; GO:0016020; GO:0016324; GO:0021630; GO:0031982; GO:0035725; GO:0036368; GO:0042756; GO:0048306; GO:0050849; GO:0050911; GO:0055074; GO:0070588; GO:0071486; GO:0071805; GO:0086009; GO:0097186; GO:0098703; GO:0120199; GO:1903998; GO:1990034; GO:1990680; GO:1990834 34161 FUN_016465 4022 2333 2100 5496 5759 ptg000011l:3438756-3442735 Q9UHI7 6.7e-70 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 34162 FUN_016465 4022 2333 2100 5496 5759 ptg000011l:3438756-3442735 Q9UHI7 6.7e-70 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 34163 FUN_016465 4022 2333 2100 5496 5759 ptg000011l:3438756-3442735 Q9UHI7 6.7e-70 Solute carrier family 23 member 1 (Na(+)/L-ascorbic acid transporter 1) (Sodium-dependent vitamin C transporter 1) (hSVCT1) (Yolk sac permease-like molecule 3) Homo sapiens (Human) brain development [GO:0007420]; dehydroascorbic acid transport [GO:0070837]; L-ascorbic acid metabolic process [GO:0019852]; L-ascorbic acid transmembrane transport [GO:0015882]; lung development [GO:0030324]; nucleobase transport [GO:0015851]; response to toxic substance [GO:0009636]; sodium ion transport [GO:0006814] GO:0005737; GO:0005886; GO:0005903; GO:0006814; GO:0007420; GO:0008520; GO:0009636; GO:0009925; GO:0015081; GO:0015205; GO:0015229; GO:0015851; GO:0015882; GO:0016324; GO:0019852; GO:0030324; GO:0033300; GO:0043229; GO:0070062; GO:0070837 34164 FUN_016466 1428 928 751 1193 1072 NA NA NA NA NA NA NA 34165 FUN_016469 8285 10056 6012 6154 3281 NA NA NA NA NA NA NA 34166 FUN_016468 1392 815 471 1013 1058 NA NA NA NA NA NA NA 34167 FUN_043526 207 53 65 189 159 NA NA NA NA NA NA NA 34168 FUN_043527 52 0 0 8 70 NA NA NA NA NA NA NA 34169 FUN_043524 40 23 55 16 84 NA NA NA NA NA NA NA 34170 FUN_043525 60 36 0 19 38 NA NA NA NA NA NA NA 34171 FUN_043522 386 1167 633 667 426 NA NA NA NA NA NA NA 34172 FUN_043523 11 17 22 40 16 NA NA NA NA NA NA NA 34173 FUN_043520 8339 10724 5319 11738 9466 ptg000047l:9526985-9528207 Q6QLW4 8.5e-29 Cytochrome c Pectinaria gouldii (Trumpet worm) (Ice-cream cone worm) NA GO:0005758; GO:0009055; GO:0020037; GO:0046872; GO:0070469 34174 FUN_043521 7700 7657 5112 7215 5424 NA NA NA NA NA NA NA 34175 FUN_043528 178 73 17 58 55 NA NA NA NA NA NA NA 34176 FUN_043529 1074 975 411 579 346 NA NA NA NA NA NA NA 34177 FUN_028759 275 85 91 323 194 NA NA NA NA NA NA NA 34178 FUN_014667 1701 1019 711 780 528 NA NA NA NA NA NA NA 34179 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34180 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 4.43e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34181 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 2.73e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34182 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 2.86e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34183 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 6.23e-117 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34184 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 9.89e-112 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34185 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 1.06e-105 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34186 FUN_028757 26 11 0 30 8 ptg000022l:3589481-3598051 Q96AY4 3.72e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34187 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 3.4e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34188 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 3.4e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34189 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 4.54e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34190 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 4.54e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34191 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 4.27e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34192 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 4.27e-82 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34193 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 7.57e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34194 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 7.57e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34195 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 2.21e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34196 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 2.21e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34197 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 6.85e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34198 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 6.85e-72 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34199 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 1.19e-62 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34200 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 1.77e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34201 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 1.21e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34202 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 1.21e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34203 FUN_028701 0 0 0 12 79 ptg000022l:2880635-2884841 Q96AY4 1.64e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34204 FUN_023136 2658 1367 1791 3699 2345 NA NA NA NA NA NA NA 34205 FUN_028703 0 17 0 30 0 NA NA NA NA NA NA NA 34206 FUN_023134 213758 153253 119465 142378 64391 ptg000017l:4029351-4046028 P26632 5.26e-50 Early growth response protein 1 (EGR-1) (Zinc finger protein Krox-24) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; circadian regulation of gene expression [GO:0032922]; embryonic retina morphogenesis in camera-type eye [GO:0060059]; embryonic viscerocranium morphogenesis [GO:0048703]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0005737; GO:0006357; GO:0008270; GO:0010385; GO:0032922; GO:0043010; GO:0043565; GO:0044729; GO:0045893; GO:0045944; GO:0048703; GO:0060059; GO:1990841 34207 FUN_023131 13 40 0 15 73 NA NA NA NA NA NA NA 34208 FUN_028709 13 11 4 0 6 NA NA NA NA NA NA NA 34209 FUN_023139 827 288 571 592 738 ptg000017l:4092847-4104121 Q12888 1.16e-24 TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; cellular response to X-ray [GO:0071481]; DNA damage checkpoint signaling [GO:0000077]; double-strand break repair via nonhomologous end joining [GO:0006303]; negative regulation of double-strand break repair via homologous recombination [GO:2000042]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of isotype switching [GO:0045830]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein homooligomerization [GO:0051260] GO:0000077; GO:0000776; GO:0000781; GO:0002039; GO:0003684; GO:0003712; GO:0005634; GO:0005654; GO:0005657; GO:0005737; GO:0006303; GO:0006974; GO:0016604; GO:0035064; GO:0035861; GO:0042162; GO:0042393; GO:0045830; GO:0045893; GO:0045944; GO:0051091; GO:0051260; GO:0061629; GO:0061649; GO:0071481; GO:1990391; GO:2000042 34210 FUN_023138 577 593 346 455 821 NA NA NA NA NA NA NA 34211 FUN_041018 33 277 58 44 81 NA NA NA NA NA NA NA 34212 FUN_041011 11 104 9 31 31 NA NA NA NA NA NA NA 34213 FUN_041013 21 9 36 19 23 NA NA NA NA NA NA NA 34214 FUN_041014 22 5 7 6 17 NA NA NA NA NA NA NA 34215 FUN_041017 33 61 280 101 12 NA NA NA NA NA NA NA 34216 FUN_009370 210 129 0 93 29 NA NA NA NA NA NA NA 34217 FUN_034358 18 0 0 0 29 ptg000024l:7964108-7977094 A3RL54 3.31e-23 NA NA NA NA 34218 FUN_034358 18 0 0 0 29 ptg000024l:7964108-7977094 A3RL54 9.64e-21 NA NA NA NA 34219 FUN_043021 265 648 138 168 227 NA NA NA NA NA NA NA 34220 FUN_016056 215 89 150 104 153 NA NA NA NA NA NA NA 34221 FUN_043020 202 46 51 251 204 NA NA NA NA NA NA NA 34222 FUN_022664 1211 712 530 772 597 NA NA NA NA NA NA NA 34223 FUN_022665 237 1534 1251 2140 1115 ptg000016l:12152003-12153059 Q5RA50 3.61e-27 Protein FAM124A Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA NA 34224 FUN_022666 36 36 39 30 62 NA NA NA NA NA NA NA 34225 FUN_022667 0 11 0 0 8 ptg000016l:12165450-12167993 P11009 2.18e-27 Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK) Gallus gallus (Chicken) phosphocreatine biosynthetic process [GO:0046314]; phosphorylation [GO:0016310] GO:0004111; GO:0005524; GO:0005743; GO:0016310; GO:0046314 34226 FUN_022660 140 110 26 64 36 NA NA NA NA NA NA NA 34227 FUN_022661 139 31 55 178 64 ptg000016l:12073443-12075525 E7FAM5 4.6e-110 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 34228 FUN_022662 3944 2501 1809 3145 2430 NA NA NA NA NA NA NA 34229 FUN_022663 727 533 552 770 360 ptg000016l:12122697-12125039 Q921I9 8.16e-55 Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) Mus musculus (Mouse) defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000460; GO:0000791; GO:0000956; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006396; GO:0006401; GO:0016075; GO:0030307; GO:0034427; GO:0034475; GO:0035925; GO:0043231; GO:0045006; GO:0051607; GO:0071028; GO:0071044; GO:0071051; GO:0101019 34230 FUN_022663 727 533 552 770 360 ptg000016l:12122697-12125039 Q921I9 2.53e-33 Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) Mus musculus (Mouse) defense response to virus [GO:0051607]; DNA deamination [GO:0045006]; histone mRNA catabolic process [GO:0071044]; maturation of 5.8S rRNA [GO:0000460]; nuclear mRNA surveillance [GO:0071028]; nuclear-transcribed mRNA catabolic process [GO:0000956]; nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [GO:0034427]; polyadenylation-dependent snoRNA 3'-end processing [GO:0071051]; positive regulation of cell growth [GO:0030307]; RNA catabolic process [GO:0006401]; RNA processing [GO:0006396]; rRNA catabolic process [GO:0016075]; U4 snRNA 3'-end processing [GO:0034475] GO:0000176; GO:0000177; GO:0000178; GO:0000460; GO:0000791; GO:0000956; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0006396; GO:0006401; GO:0016075; GO:0030307; GO:0034427; GO:0034475; GO:0035925; GO:0043231; GO:0045006; GO:0051607; GO:0071028; GO:0071044; GO:0071051; GO:0101019 34231 FUN_022668 644 439 248 426 246 NA NA NA NA NA NA NA 34232 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.81e-155 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34233 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 3.54e-146 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34234 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.16e-132 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34235 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.16e-132 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34236 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.73e-56 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34237 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.73e-56 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34238 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.95e-53 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34239 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 7.9e-38 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34240 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 6.46e-35 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34241 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.06e-33 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34242 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 1.74e-31 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34243 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 2.19e-26 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34244 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 2.23e-26 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34245 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 7.76e-26 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34246 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 4.31e-23 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34247 FUN_022669 4432 2657 2312 4949 4738 ptg000016l:12187426-12236747 B8UU59 6.6e-22 Polycystic kidney disease 1-related protein Acropora millepora (Staghorn coral) (Heteropora millepora) kidney development [GO:0001822] GO:0001822; GO:0005929; GO:0016020 34248 FUN_014980 3217 1516 2029 1830 1272 NA NA NA NA NA NA NA 34249 FUN_014981 2031 1042 697 1353 1029 NA NA NA NA NA NA NA 34250 FUN_014982 711 261 209 538 255 ptg000009l:4989552-4992711 P51607 4.65e-41 N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP) Rattus norvegicus (Rat) carbohydrate metabolic process [GO:0005975]; N-acetylglucosamine metabolic process [GO:0006044]; N-acetylmannosamine metabolic process [GO:0006051]; N-acetylneuraminate catabolic process [GO:0019262]; negative regulation of catalytic activity [GO:0043086]; negative regulation of endopeptidase activity [GO:0010951] GO:0004857; GO:0005524; GO:0005975; GO:0006044; GO:0006051; GO:0010951; GO:0017076; GO:0019262; GO:0030414; GO:0042802; GO:0043086; GO:0050121 34251 FUN_029060 262 129 220 196 238 ptg000022l:7744002-7761404 A8E657 7.25e-31 Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] Bos taurus (Bovine) L-lysine catabolic process to acetyl-CoA via saccharopine [GO:0033512]; lysine biosynthetic process via aminoadipic acid [GO:0019878]; lysine catabolic process [GO:0006554] GO:0004753; GO:0005737; GO:0005739; GO:0006554; GO:0019878; GO:0033512; GO:0047130; GO:0047131 34252 FUN_029067 1904 1401 1054 3316 2305 NA NA NA NA NA NA NA 34253 FUN_029066 342 253 50 181 212 NA NA NA NA NA NA NA 34254 FUN_030453 10 0 12 0 36 ptg000023l:10898634-10899397 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34255 FUN_029065 1083 465 521 1176 940 ptg000022l:7806960-7807836 Q9EPW2 1.3e-44 Krueppel-like factor 15 (Cardiovascular Krueppel-like factor) Mus musculus (Mouse) cardiac muscle hypertrophy in response to stress [GO:0014898]; cellular glucose homeostasis [GO:0001678]; cellular response to peptide [GO:1901653]; glial cell differentiation [GO:0010001]; negative regulation of peptidyl-lysine acetylation [GO:2000757]; podocyte differentiation [GO:0072112]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of glucose import [GO:0046326]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of gene expression [GO:0010468]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of Wnt signaling pathway [GO:0030111]; response to insulin [GO:0032868] GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001678; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0010001; GO:0010468; GO:0014898; GO:0016607; GO:0030111; GO:0032868; GO:0043231; GO:0045893; GO:0045944; GO:0046326; GO:0046872; GO:0072112; GO:1901653; GO:1990837; GO:2000757 34256 FUN_010041 0 37 0 0 32 NA NA NA NA NA NA NA 34257 FUN_010040 0 0 27 31 0 NA NA NA NA NA NA NA 34258 FUN_010043 0 6 0 0 0 NA NA NA NA NA NA NA 34259 FUN_010044 0 0 0 0 15 NA NA NA NA NA NA NA 34260 FUN_001223 22 0 0 15 15 NA NA NA NA NA NA NA 34261 FUN_001220 7624 1776 1256 5230 701 NA NA NA NA NA NA NA 34262 FUN_015728 0 52 0 46 3 NA NA NA NA NA NA NA 34263 FUN_008138 11 48 5 15 29 NA NA NA NA NA NA NA 34264 FUN_008139 152 366 284 429 272 NA NA NA NA NA NA NA 34265 FUN_024549 7 0 0 0 0 NA NA NA NA NA NA NA 34266 FUN_024548 31 22 15 49 27 NA NA NA NA NA NA NA 34267 FUN_001225 212 152 44 160 152 ntLink_6:9952301-9961109 P42893 2.36e-31 Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; axonogenesis involved in innervation [GO:0060385]; blood vessel diameter maintenance [GO:0097746]; bradykinin catabolic process [GO:0010815]; calcitonin catabolic process [GO:0010816]; ear development [GO:0043583]; embryonic digit morphogenesis [GO:0042733]; embryonic heart tube development [GO:0035050]; endothelin maturation [GO:0034959]; gene expression [GO:0010467]; heart development [GO:0007507]; hormone catabolic process [GO:0042447]; neuron projection development [GO:0031175]; peptide hormone processing [GO:0016486]; pharyngeal system development [GO:0060037]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cardiac muscle hypertrophy [GO:0010613]; positive regulation of G protein-coupled receptor signaling pathway [GO:0045745]; positive regulation of receptor recycling [GO:0001921]; protein processing [GO:0016485]; regulation of blood pressure [GO:0008217]; regulation of ERK1 and ERK2 cascade [GO:0070372]; response to cadmium ion [GO:0046686]; response to hypoxia [GO:0001666]; response to muscle stretch [GO:0035994]; response to xenobiotic stimulus [GO:0009410]; semaphorin-plexin signaling pathway involved in axon guidance [GO:1902287]; substance P catabolic process [GO:0010814]; sympathetic neuron axon guidance [GO:0097492] GO:0001666; GO:0001921; GO:0004175; GO:0004222; GO:0005768; GO:0005769; GO:0005886; GO:0006915; GO:0007507; GO:0008217; GO:0008270; GO:0009410; GO:0009897; GO:0010467; GO:0010613; GO:0010814; GO:0010815; GO:0010816; GO:0016020; GO:0016485; GO:0016486; GO:0030141; GO:0031175; GO:0031410; GO:0031982; GO:0033093; GO:0034959; GO:0035050; GO:0035994; GO:0042447; GO:0042733; GO:0042802; GO:0042803; GO:0043583; GO:0043950; GO:0045745; GO:0046686; GO:0048471; GO:0060037; GO:0060385; GO:0070372; GO:0097492; GO:0097746; GO:1902287 34268 FUN_031320 135 29 108 0 189 ptg000023l:19447255-19473999 Q7RTR2 1.61e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34269 FUN_031320 135 29 108 0 189 ptg000023l:19447255-19473999 Q7RTR2 1.6e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34270 FUN_031320 135 29 108 0 189 ptg000023l:19447255-19473999 Q7RTR2 6.76e-43 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34271 FUN_031320 135 29 108 0 189 ptg000023l:19447255-19473999 Q7RTR2 7.1e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34272 FUN_031320 135 29 108 0 189 ptg000023l:19447255-19473999 Q7RTR2 1.54e-37 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34273 FUN_024543 0 17 12 8 25 NA NA NA NA NA NA NA 34274 FUN_008131 0 0 0 0 10 NA NA NA NA NA NA NA 34275 FUN_008132 210 453 117 181 92 NA NA NA NA NA NA NA 34276 FUN_024540 0 7 0 4 1 NA NA NA NA NA NA NA 34277 FUN_008135 68 66 43 134 130 NA NA NA NA NA NA NA 34278 FUN_024545 418 4 147 444 6 NA NA NA NA NA NA NA 34279 FUN_008137 35 44 15 90 61 NA NA NA NA NA NA NA 34280 FUN_036114 638 522 354 361 421 ptg000025l:15518783-15522519 Q8CG07 2.9e-37 ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) Rattus norvegicus (Rat) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000731; GO:0000781; GO:0003677; GO:0005524; GO:0005634; GO:0006261; GO:0008047; GO:0016887; GO:0017116; GO:0030174; GO:0042802; GO:0045087; GO:0046872; GO:0048471 34281 FUN_036114 638 522 354 361 421 ptg000025l:15518783-15522519 Q8CG07 6.44e-34 ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) Rattus norvegicus (Rat) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000731; GO:0000781; GO:0003677; GO:0005524; GO:0005634; GO:0006261; GO:0008047; GO:0016887; GO:0017116; GO:0030174; GO:0042802; GO:0045087; GO:0046872; GO:0048471 34282 FUN_036114 638 522 354 361 421 ptg000025l:15518783-15522519 Q8CG07 6.44e-34 ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) Rattus norvegicus (Rat) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000731; GO:0000781; GO:0003677; GO:0005524; GO:0005634; GO:0006261; GO:0008047; GO:0016887; GO:0017116; GO:0030174; GO:0042802; GO:0045087; GO:0046872; GO:0048471 34283 FUN_036114 638 522 354 361 421 ptg000025l:15518783-15522519 Q8CG07 2.34e-31 ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1) Rattus norvegicus (Rat) DNA synthesis involved in DNA repair [GO:0000731]; DNA-templated DNA replication [GO:0006261]; innate immune response [GO:0045087]; regulation of DNA-templated DNA replication initiation [GO:0030174] GO:0000731; GO:0000781; GO:0003677; GO:0005524; GO:0005634; GO:0006261; GO:0008047; GO:0016887; GO:0017116; GO:0030174; GO:0042802; GO:0045087; GO:0046872; GO:0048471 34284 FUN_036113 0 0 0 0 9 NA NA NA NA NA NA NA 34285 FUN_031327 380 130 501 222 1073 ptg000023l:19660133-19670358 Q7RTR2 1.44e-69 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34286 FUN_031327 380 130 501 222 1073 ptg000023l:19660133-19670358 Q7RTR2 5.09e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34287 FUN_031327 380 130 501 222 1073 ptg000023l:19660133-19670358 Q7RTR2 1.88e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34288 FUN_031327 380 130 501 222 1073 ptg000023l:19660133-19670358 Q7RTR2 4.06e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34289 FUN_031327 380 130 501 222 1073 ptg000023l:19660133-19670358 Q7RTR2 1.03e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 34290 FUN_015179 262 187 304 279 497 NA NA NA NA NA NA NA 34291 FUN_015176 41 30 154 190 343 NA NA NA NA NA NA NA 34292 FUN_031326 0 0 0 29 8 NA NA NA NA NA NA NA 34293 FUN_015172 6 0 0 0 0 NA NA NA NA NA NA NA 34294 FUN_015173 215 0 0 259 0 NA NA NA NA NA NA NA 34295 FUN_015170 1 12 0 24 6 NA NA NA NA NA NA NA 34296 FUN_043776 234 104 136 273 66 NA NA NA NA NA NA NA 34297 FUN_003651 0 0 0 54 0 NA NA NA NA NA NA NA 34298 FUN_038558 67 90 19 127 112 ptg000027l:8721383-8724731 Q64WY5 1.42e-46 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Bacteroides fragilis (strain YCH46) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 34299 FUN_038558 67 90 19 127 112 ptg000027l:8721383-8724731 Q64WY5 6.95e-34 Probable endonuclease 4 (EC 3.1.21.2) (Endodeoxyribonuclease IV) (Endonuclease IV) Bacteroides fragilis (strain YCH46) DNA repair [GO:0006281] GO:0003677; GO:0006281; GO:0008270; GO:0008833 34300 FUN_038555 57 47 0 0 16 NA NA NA NA NA NA NA 34301 FUN_038554 24 6 0 0 8 NA NA NA NA NA NA NA 34302 FUN_038557 396 290 265 691 423 NA NA NA NA NA NA NA 34303 FUN_038556 9 0 0 17 0 NA NA NA NA NA NA NA 34304 FUN_038551 206 233 139 229 148 ptg000027l:8591077-8592019 F1R332 4.1e-29 Galanin receptor 2a Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 34305 FUN_038550 373 273 151 382 97 NA NA NA NA NA NA NA 34306 FUN_038553 268 275 95 63 102 NA NA NA NA NA NA NA 34307 FUN_038552 16 0 0 21 23 ptg000027l:8595874-8600837 E7F7V7 1.39e-22 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 34308 FUN_019873 0 0 0 0 130 NA NA NA NA NA NA NA 34309 FUN_019872 0 0 0 0 32 NA NA NA NA NA NA NA 34310 FUN_019876 0 0 0 0 130 NA NA NA NA NA NA NA 34311 FUN_019875 0 35 13 0 0 NA NA NA NA NA NA NA 34312 FUN_019874 66 19 43 18 234 NA NA NA NA NA NA NA 34313 FUN_008258 1495 780 797 1005 806 ptg000002l:9728249-9734082 P37285 5.4e-27 Kinesin light chain 1 (KLC 1) Rattus norvegicus (Rat) axo-dendritic transport [GO:0008088]; intracellular protein transport [GO:0006886]; microtubule-based movement [GO:0007018]; protein localization to synapse [GO:0035418]; stress granule disassembly [GO:0035617] GO:0005737; GO:0005829; GO:0005871; GO:0005874; GO:0006886; GO:0007018; GO:0008088; GO:0015631; GO:0016020; GO:0019894; GO:0030424; GO:0030426; GO:0031410; GO:0031982; GO:0035253; GO:0035418; GO:0035617; GO:0043005; GO:0043025; GO:0043227 34314 FUN_027930 553 270 256 272 195 ptg000021l:13415630-13418493 Q9UBM8 1.66e-24 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-acetylglucosaminyltransferase IV homolog) (hGnT-IV-H) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GlcNAc-T IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Homo sapiens (Human) protein N-linked glycosylation [GO:0006487]; viral protein processing [GO:0019082] GO:0000139; GO:0006487; GO:0008375; GO:0008454; GO:0019082; GO:0046872 34315 FUN_015828 0 4 11 12 0 NA NA NA NA NA NA NA 34316 FUN_015827 4 17 0 0 0 NA NA NA NA NA NA NA 34317 FUN_015820 0 13 0 5 37 NA NA NA NA NA NA NA 34318 FUN_039200 109 58 11 14 6 NA NA NA NA NA NA NA 34319 FUN_039206 42 8 41 1847 43 NA NA NA NA NA NA NA 34320 FUN_039207 0 0 0 0 7 NA NA NA NA NA NA NA 34321 FUN_039204 9 0 0 0 49 NA NA NA NA NA NA NA 34322 FUN_039208 3 0 0 66 0 NA NA NA NA NA NA NA 34323 FUN_039209 0 0 0 149 0 NA NA NA NA NA NA NA 34324 FUN_027936 1455 716 1138 1556 959 NA NA NA NA NA NA NA 34325 FUN_044140 0 0 0 0 7 NA NA NA NA NA NA NA 34326 FUN_016728 61 4 0 0 0 NA NA NA NA NA NA NA 34327 FUN_016729 2049 784 249 1188 2116 NA NA NA NA NA NA NA 34328 FUN_027935 437 239 420 928 605 NA NA NA NA NA NA NA 34329 FUN_014750 98 94 42 91 17 ptg000009l:2758009-2759284 Q5F2F2 4.98e-64 Protein ABHD15 (Alpha/beta hydrolase domain-containing protein 15) (Abhydrolase domain-containing protein 15) Mus musculus (Mouse) cellular lipid metabolic process [GO:0044255] GO:0005576; GO:0034338; GO:0044255; GO:0047372 34330 FUN_027158 0 4 5 5 24 NA NA NA NA NA NA NA 34331 FUN_027155 6 4 7 6 123 NA NA NA NA NA NA NA 34332 FUN_027156 0 0 4 0 17 NA NA NA NA NA NA NA 34333 FUN_016722 249 95 102 143 127 ptg000011l:6694022-6695126 P48630 2.17e-124 Omega-6 fatty acid desaturase, endoplasmic reticulum isozyme 1 (EC 1.14.19.-) Glycine max (Soybean) (Glycine hispida) unsaturated fatty acid biosynthetic process [GO:0006636] GO:0005789; GO:0006636; GO:0016491 34334 FUN_042843 2279 1548 755 1255 2329 NA NA NA NA NA NA NA 34335 FUN_016720 1185 1034 639 730 486 ptg000011l:6648866-6662043 P36897 2.89e-52 TGF-beta receptor type-1 (TGFR-1) (EC 2.7.11.30) (Activin A receptor type II-like protein kinase of 53kD) (Activin receptor-like kinase 5) (ALK-5) (ALK5) (Serine/threonine-protein kinase receptor R4) (SKR4) (TGF-beta type I receptor) (Transforming growth factor-beta receptor type I) (TGF-beta receptor type I) (TbetaR-I) Homo sapiens (Human) activin receptor signaling pathway [GO:0032924]; angiogenesis involved in coronary vascular morphogenesis [GO:0060978]; anterior/posterior pattern specification [GO:0009952]; apoptotic process [GO:0006915]; artery morphogenesis [GO:0048844]; blastocyst development [GO:0001824]; cardiac epithelial to mesenchymal transition [GO:0060317]; cell motility [GO:0048870]; cellular response to growth factor stimulus [GO:0071363]; cellular response to transforming growth factor beta stimulus [GO:0071560]; collagen fibril organization [GO:0030199]; coronary artery morphogenesis [GO:0060982]; embryonic cranial skeleton morphogenesis [GO:0048701]; endothelial cell activation [GO:0042118]; endothelial cell migration [GO:0043542]; endothelial cell proliferation [GO:0001935]; epicardium morphogenesis [GO:1905223]; epithelial to mesenchymal transition [GO:0001837]; extracellular structure organization [GO:0043062]; filopodium assembly [GO:0046847]; germ cell migration [GO:0008354]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; intracellular signal transduction [GO:0035556]; kidney development [GO:0001822]; lens development in camera-type eye [GO:0002088]; male gonad development [GO:0008584]; mesenchymal cell differentiation [GO:0048762]; negative regulation of chondrocyte differentiation [GO:0032331]; negative regulation of endothelial cell proliferation [GO:0001937]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; nervous system development [GO:0007399]; neuron fate commitment [GO:0048663]; parathyroid gland development [GO:0060017]; pathway-restricted SMAD protein phosphorylation [GO:0060389]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; pharyngeal system development [GO:0060037]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of cell growth [GO:0030307]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of endothelial cell proliferation [GO:0001938]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation [GO:1905007]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of gene expression [GO:0010628]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of pathway-restricted SMAD protein phosphorylation [GO:0010862]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of SMAD protein signal transduction [GO:0060391]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of tight junction disassembly [GO:1905075]; post-embryonic development [GO:0009791]; protein phosphorylation [GO:0006468]; regulation of cardiac muscle cell proliferation [GO:0060043]; regulation of cell cycle [GO:0051726]; regulation of DNA-templated transcription [GO:0006355]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of protein binding [GO:0043393]; regulation of protein ubiquitination [GO:0031396]; response to cholesterol [GO:0070723]; roof of mouth development [GO:0060021]; signal transduction [GO:0007165]; skeletal system development [GO:0001501]; skeletal system morphogenesis [GO:0048705]; thymus development [GO:0048538]; transforming growth factor beta receptor signaling pathway [GO:0007179]; ventricular compact myocardium morphogenesis [GO:0003223]; ventricular septum morphogenesis [GO:0060412]; ventricular trabecula myocardium morphogenesis [GO:0003222]; wound healing [GO:0042060] GO:0001501; GO:0001701; GO:0001822; GO:0001824; GO:0001837; GO:0001935; GO:0001937; GO:0001938; GO:0002088; GO:0003222; GO:0003223; GO:0004672; GO:0004674; GO:0005024; GO:0005025; GO:0005114; GO:0005524; GO:0005634; GO:0005768; GO:0005886; GO:0005923; GO:0006355; GO:0006468; GO:0006915; GO:0007165; GO:0007179; GO:0007399; GO:0007507; GO:0008284; GO:0008354; GO:0008584; GO:0009791; GO:0009952; GO:0009986; GO:0010468; GO:0010628; GO:0010717; GO:0010718; GO:0010862; GO:0016020; GO:0016361; GO:0018105; GO:0018107; GO:0030199; GO:0030307; GO:0030335; GO:0031396; GO:0032331; GO:0032924; GO:0035556; GO:0042060; GO:0042118; GO:0043062; GO:0043235; GO:0043393; GO:0043410; GO:0043542; GO:0045121; GO:0045893; GO:0046332; GO:0046847; GO:0046872; GO:0048179; GO:0048185; GO:0048538; GO:0048663; GO:0048701; GO:0048705; GO:0048762; GO:0048844; GO:0048870; GO:0050431; GO:0051491; GO:0051496; GO:0051726; GO:0051897; GO:0060017; GO:0060021; GO:0060037; GO:0060043; GO:0060317; GO:0060389; GO:0060391; GO:0060412; GO:0060978; GO:0060982; GO:0070021; GO:0070411; GO:0070723; GO:0071363; GO:0071560; GO:1905007; GO:1905075; GO:1905223; GO:2001235; GO:2001237 34336 FUN_016721 11713 7843 5031 23223 12730 NA NA NA NA NA NA NA 34337 FUN_016726 457 2489 526 285 703 NA NA NA NA NA NA NA 34338 FUN_016727 157 318 59 5 219 NA NA NA NA NA NA NA 34339 FUN_016724 1447 851 343 798 263 NA NA NA NA NA NA NA 34340 FUN_042845 42 23 12 0 63 NA NA NA NA NA NA NA 34341 FUN_040659 0 7 18 18 9 NA NA NA NA NA NA NA 34342 FUN_010138 23 0 27 92 22 NA NA NA NA NA NA NA 34343 FUN_023496 342 213 293 483 372 NA NA NA NA NA NA NA 34344 FUN_044147 5 8 15 4 130 NA NA NA NA NA NA NA 34345 FUN_010131 3 0 0 3 10 NA NA NA NA NA NA NA 34346 FUN_023278 0 31 0 44 0 ptg000017l:5875608-5877392 A0A2B4SJA1 2.03e-91 NA NA NA NA 34347 FUN_023279 95 1357 192 238 884 NA NA NA NA NA NA NA 34348 FUN_040650 0 30 20 0 5 NA NA NA NA NA NA NA 34349 FUN_023274 3572 2144 1229 1653 1088 ptg000017l:5862564-5865290 Q10B63 1.66e-29 Probable acylpyruvase FAHD2, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 2) (FAH domain-containing protein 2) Oryza sativa subsp. japonica (Rice) NA GO:0005739; GO:0018773; GO:0046872; GO:0047621 34350 FUN_023276 1496 776 439 443 947 ptg000017l:5867656-5869875 Q6AYQ8 2.5e-59 Acylpyruvase FAHD1, mitochondrial (EC 3.7.1.5) (Fumarylacetoacetate hydrolase domain-containing protein 1) (Oxaloacetate decarboxylase) (OAA decarboxylase) (EC 4.1.1.112) Rattus norvegicus (Rat) pyruvate metabolic process [GO:0006090] GO:0005654; GO:0005739; GO:0005829; GO:0006090; GO:0008948; GO:0018773; GO:0034545; GO:0046872; GO:0047621 34351 FUN_023277 3671 5090 2370 6160 2319 ptg000017l:5870974-5873092 A0A2B4SJA1 1.57e-94 NA NA NA NA 34352 FUN_023270 777 1157 403 729 363 NA NA NA NA NA NA NA 34353 FUN_023272 3360 4913 2790 4069 4720 NA NA NA NA NA NA NA 34354 FUN_023273 68 251 192 109 160 NA NA NA NA NA NA NA 34355 FUN_010134 3 0 0 0 8 NA NA NA NA NA NA NA 34356 FUN_018287 0 19 16 117 36 NA NA NA NA NA NA NA 34357 FUN_018285 263 21 45 115 110 NA NA NA NA NA NA NA 34358 FUN_018284 72 45 0 23 0 NA NA NA NA NA NA NA 34359 FUN_018283 129 4 70 82 178 NA NA NA NA NA NA NA 34360 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 8.77e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34361 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 4.77e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34362 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 6.54e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34363 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 2.46e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34364 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 3.81e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34365 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 5.37e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34366 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 6.36e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34367 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 2.6e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34368 FUN_018282 773 146 297 447 711 ptg000012l:7094320-7107660 Q96AY4 1.33e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34369 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 5.08e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34370 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 5.08e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34371 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 5.08e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34372 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 1.4e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34373 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 1.4e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34374 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 1.4e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34375 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 2.64e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34376 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 2.64e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34377 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 2.64e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34378 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 8.18e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34379 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 8.18e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34380 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 8.18e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34381 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 5.34e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34382 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 5.34e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34383 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 5.34e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34384 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 3.26e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34385 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 3.26e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34386 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 3.26e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34387 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 1.73e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34388 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 4.3e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34389 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 8.2e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34390 FUN_018281 83 0 50 145 81 ptg000012l:7093178-7094105 Q80XJ3 8.2e-21 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 34391 FUN_018280 914 405 485 1571 1042 NA NA NA NA NA NA NA 34392 FUN_010136 2 13 12 11 5 NA NA NA NA NA NA NA 34393 FUN_018289 0 0 34 0 0 NA NA NA NA NA NA NA 34394 FUN_018288 0 7 4 0 7 NA NA NA NA NA NA NA 34395 FUN_037377 1061 883 465 586 677 ptg000026l:9766872-9777495 Q4R333 1.17e-47 Actin-like protein 6A (BRG1-associated factor 53A) (BAF53A) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) chromatin organization [GO:0006325]; DNA recombination [GO:0006310]; DNA repair [GO:0006281]; histone H2A acetylation [GO:0043968]; histone H4 acetylation [GO:0043967]; nervous system development [GO:0007399] GO:0006281; GO:0006310; GO:0006325; GO:0007399; GO:0035267; GO:0043967; GO:0043968; GO:0071564 34396 FUN_036115 350 498 210 325 215 ptg000025l:15522863-15527223 A7S6Y0 1.54e-23 Protein SYS1 homolog Nematostella vectensis (Starlet sea anemone) Golgi to endosome transport [GO:0006895]; Golgi to plasma membrane protein transport [GO:0043001]; protein localization to Golgi apparatus [GO:0034067] GO:0000139; GO:0005802; GO:0005829; GO:0006895; GO:0034067; GO:0043001 34397 FUN_037379 31 25 18 12 56 NA NA NA NA NA NA NA 34398 FUN_039989 0 13 0 0 0 NA NA NA NA NA NA NA 34399 FUN_039988 0 0 0 0 29 NA NA NA NA NA NA NA 34400 FUN_033929 1486 1413 555 1279 920 NA NA NA NA NA NA NA 34401 FUN_033928 650 398 517 724 679 NA NA NA NA NA NA NA 34402 FUN_033925 38 22 29 42 82 NA NA NA NA NA NA NA 34403 FUN_033924 3267 2970 1912 2987 3164 NA NA NA NA NA NA NA 34404 FUN_039983 79 87 25 24 81 NA NA NA NA NA NA NA 34405 FUN_039982 4125 2750 2172 3604 3476 NA NA NA NA NA NA NA 34406 FUN_033921 835 370 373 628 556 NA NA NA NA NA NA NA 34407 FUN_039987 10 44 16 24 20 NA NA NA NA NA NA NA 34408 FUN_033922 2927 2719 1194 3793 3483 NA NA NA NA NA NA NA 34409 FUN_018863 0 0 42 0 0 NA NA NA NA NA NA NA 34410 FUN_018862 0 0 20 0 34 ptg000012l:14489837-14512829 P14381 1.14e-96 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 34411 FUN_018862 0 0 20 0 34 ptg000012l:14489837-14512829 P14381 3.39e-96 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 34412 FUN_018861 20 25 21 5 1 NA NA NA NA NA NA NA 34413 FUN_044023 1537 6477 11264 3676 2693 NA NA NA NA NA NA NA 34414 FUN_018867 48 15 9 9 13 NA NA NA NA NA NA NA 34415 FUN_018866 589 554 283 388 284 ptg000012l:14628440-14638164 Q5FVI3 1.31e-41 Leucine-rich repeat-containing protein 57 Rattus norvegicus (Rat) NA GO:0016020 34416 FUN_018865 68 88 38 29 133 NA NA NA NA NA NA NA 34417 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 1.98e-59 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34418 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 4.71e-40 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34419 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 1.15e-29 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34420 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 2.52e-28 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34421 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 5.77e-28 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34422 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 1.2e-23 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34423 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 1.82e-21 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34424 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 2.5e-21 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34425 FUN_018864 2821 1726 2149 4039 4747 ptg000012l:14525982-14619480 C0HL13 6.65e-21 Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin) Sus scrofa (Pig) coronary artery morphogenesis [GO:0060982]; folate import across plasma membrane [GO:1904447]; male gonad development [GO:0008584]; metal ion transport [GO:0030001]; negative regulation of BMP signaling pathway [GO:0030514]; neural tube closure [GO:0001843]; neuron projection arborization [GO:0140058]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of neurogenesis [GO:0050769]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; pulmonary artery morphogenesis [GO:0061156]; receptor-mediated endocytosis [GO:0006898]; secondary heart field specification [GO:0003139]; sensory perception of sound [GO:0007605]; vagina development [GO:0060068]; ventricular compact myocardium morphogenesis [GO:0003223] GO:0001843; GO:0003139; GO:0003148; GO:0003223; GO:0005509; GO:0005905; GO:0006898; GO:0007605; GO:0008584; GO:0009897; GO:0016324; GO:0017124; GO:0030001; GO:0030424; GO:0030425; GO:0030514; GO:0031526; GO:0031904; GO:0043235; GO:0050769; GO:0051087; GO:0060068; GO:0060982; GO:0061156; GO:0070447; GO:0140058; GO:1904447; GO:1905167 34426 FUN_018869 55 56 40 20 121 NA NA NA NA NA NA NA 34427 FUN_044020 12 0 16 0 13 NA NA NA NA NA NA NA 34428 FUN_016018 19 0 17 46 25 NA NA NA NA NA NA NA 34429 FUN_044021 34 6 10 2 52 NA NA NA NA NA NA NA 34430 FUN_016014 1301 843 1168 1638 1345 NA NA NA NA NA NA NA 34431 FUN_042375 70 2 11 87 392 NA NA NA NA NA NA NA 34432 FUN_016016 9491 3952 2512 4861 3371 NA NA NA NA NA NA NA 34433 FUN_021123 49 0 93 101 41 NA NA NA NA NA NA NA 34434 FUN_016017 1923 1899 1226 2623 1846 NA NA NA NA NA NA NA 34435 FUN_021124 0 0 79 0 0 NA NA NA NA NA NA NA 34436 FUN_042370 13 0 29 14 66 NA NA NA NA NA NA NA 34437 FUN_042371 19 0 0 4 0 NA NA NA NA NA NA NA 34438 FUN_042372 0 0 0 0 36 NA NA NA NA NA NA NA 34439 FUN_016013 684 303 163 1186 436 NA NA NA NA NA NA NA 34440 FUN_044024 228 4641 4804 1270 774 NA NA NA NA NA NA NA 34441 FUN_035435 0 0 22 0 6 ptg000025l:7386656-7388555 O54991 9e-28 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 34442 FUN_035434 0 8 0 0 0 NA NA NA NA NA NA NA 34443 FUN_035437 32 14 19 10 15 ptg000025l:7431025-7437091 Q94887 1.23e-28 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 34444 FUN_038619 477 753 149 539 791 NA NA NA NA NA NA NA 34445 FUN_035431 30 193 58 178 191 ptg000025l:7349600-7355258 Q94887 3.19e-29 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 34446 FUN_035430 58 48 0 51 6 ptg000025l:7316142-7346698 O54991 2.29e-32 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 34447 FUN_035430 58 48 0 51 6 ptg000025l:7316142-7346698 O54991 4.93e-31 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 34448 FUN_035430 58 48 0 51 6 ptg000025l:7316142-7346698 O54991 9.09e-29 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 34449 FUN_035433 3 0 21 9 76 ptg000025l:7368453-7372170 Q94887 3.48e-31 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 34450 FUN_035432 69 30 6 57 44 ptg000025l:7357349-7361280 O54991 3.09e-27 Contactin-associated protein 1 (Caspr) (Caspr1) (MHDNIV) (NCP1) (Neurexin IV) (Neurexin-4) (Paranodin) Mus musculus (Mouse) axonogenesis [GO:0007409]; cell adhesion [GO:0007155]; central nervous system myelination [GO:0022010]; cytoskeleton organization [GO:0007010]; mitochondrion organization [GO:0007005]; myelination [GO:0042552]; myelination in peripheral nervous system [GO:0022011]; neuromuscular junction development, skeletal muscle fiber [GO:0098529]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuromuscular process controlling posture [GO:0050884]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuronal action potential propagation [GO:0019227]; paranodal junction assembly [GO:0030913]; paranodal junction maintenance [GO:1990227]; postsynaptic density organization [GO:0097106]; protein localization to juxtaparanode region of axon [GO:0071205]; protein localization to paranode region of axon [GO:0002175]; regulation of synapse maturation [GO:0090128] GO:0002175; GO:0005886; GO:0005918; GO:0007005; GO:0007010; GO:0007155; GO:0007409; GO:0016020; GO:0017124; GO:0019227; GO:0022010; GO:0022011; GO:0030424; GO:0030913; GO:0031175; GO:0033010; GO:0033270; GO:0042552; GO:0043209; GO:0048786; GO:0048812; GO:0050884; GO:0050885; GO:0050905; GO:0071205; GO:0090128; GO:0097106; GO:0098529; GO:0098978; GO:1990227 34451 FUN_038612 31 83 14 81 19 NA NA NA NA NA NA NA 34452 FUN_038613 446 366 147 481 199 NA NA NA NA NA NA NA 34453 FUN_038610 3039 1394 1070 2505 3933 NA NA NA NA NA NA NA 34454 FUN_038611 23 87 38 34 33 NA NA NA NA NA NA NA 34455 FUN_035439 1662 1413 972 4157 2954 NA NA NA NA NA NA NA 34456 FUN_035438 37 0 47 21 18 ptg000025l:7442611-7444447 Q94887 1.48e-31 Neurexin-4 (Neurexin IV) Drosophila melanogaster (Fruit fly) axon ensheathment [GO:0008366]; cell adhesion involved in heart morphogenesis [GO:0061343]; cell-cell junction organization [GO:0045216]; dorsal closure [GO:0007391]; establishment of glial blood-brain barrier [GO:0060857]; heart process [GO:0003015]; nerve maturation [GO:0021682]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; regulation of tube size, open tracheal system [GO:0035151]; septate junction assembly [GO:0019991]; synaptic target recognition [GO:0008039]; terminal button organization [GO:0072553] GO:0003015; GO:0005886; GO:0005919; GO:0007391; GO:0008039; GO:0008104; GO:0008366; GO:0019991; GO:0021682; GO:0035151; GO:0045202; GO:0045216; GO:0048786; GO:0060857; GO:0061343; GO:0072553; GO:0097105 34457 FUN_038614 9589 5519 4820 7045 6464 ptg000027l:9329977-9351927 Q9P0X4 5.26e-26 Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3) Homo sapiens (Human) calcium ion import [GO:0070509]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165]; sleep [GO:0030431] GO:0001518; GO:0005245; GO:0005248; GO:0005886; GO:0005891; GO:0007165; GO:0008332; GO:0019228; GO:0030431; GO:0034765; GO:0043005; GO:0045956; GO:0070509; GO:0086010 34458 FUN_038614 9589 5519 4820 7045 6464 ptg000027l:9329977-9351927 Q9P0X4 4.02e-22 Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3) Homo sapiens (Human) calcium ion import [GO:0070509]; membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of ion transmembrane transport [GO:0034765]; signal transduction [GO:0007165]; sleep [GO:0030431] GO:0001518; GO:0005245; GO:0005248; GO:0005886; GO:0005891; GO:0007165; GO:0008332; GO:0019228; GO:0030431; GO:0034765; GO:0043005; GO:0045956; GO:0070509; GO:0086010 34459 FUN_038615 149 49 89 45 59 NA NA NA NA NA NA NA 34460 FUN_004934 1520 275 1601 147 1509 NA NA NA NA NA NA NA 34461 FUN_004935 0 0 5 17 41 NA NA NA NA NA NA NA 34462 FUN_004937 109 838 131 662 1212 NA NA NA NA NA NA NA 34463 FUN_004931 947 538 334 742 633 NA NA NA NA NA NA NA 34464 FUN_004932 371 156 104 567 341 NA NA NA NA NA NA NA 34465 FUN_004933 6280 3440 1616 4036 2183 NA NA NA NA NA NA NA 34466 FUN_031530 308 225 86 143 84 ptg000023l:22536852-22540761 Q54H45 1.25e-25 Probable serine/threonine-protein kinase drkB (EC 2.7.11.1) (Receptor-like kinase 2) (Receptor-like kinase B) (Vesicle-associated receptor tyrosine kinase-like protein 2) Dictyostelium discoideum (Social amoeba) protein phosphorylation [GO:0006468]; signal transduction [GO:0007165] GO:0004672; GO:0004674; GO:0005524; GO:0005737; GO:0006468; GO:0007165; GO:0016020; GO:0106310 34467 FUN_031531 554 767 760 1018 674 NA NA NA NA NA NA NA 34468 FUN_031532 0 0 0 0 249 NA NA NA NA NA NA NA 34469 FUN_031533 311 167 0 0 0 NA NA NA NA NA NA NA 34470 FUN_004938 142 709 100 686 1155 NA NA NA NA NA NA NA 34471 FUN_004939 14 56 18 122 139 NA NA NA NA NA NA NA 34472 FUN_031536 0 0 0 0 25 NA NA NA NA NA NA NA 34473 FUN_022737 34 7 12 9 19 ptg000016l:12700346-12701229 P25291 6.09e-28 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 34474 FUN_020745 0 0 0 0 9 NA NA NA NA NA NA NA 34475 FUN_020744 0 0 0 0 27 NA NA NA NA NA NA NA 34476 FUN_020747 0 0 0 0 11 NA NA NA NA NA NA NA 34477 FUN_020746 34 0 194 31 40 NA NA NA NA NA NA NA 34478 FUN_007979 67 49 49 101 82 ptg000002l:6771979-6775130 F4NUJ6 1.3e-80 tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5) Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus) mitochondrial tRNA methylation [GO:0070901]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0002939; GO:0005634; GO:0005737; GO:0005759; GO:0008175; GO:0009019; GO:0030488; GO:0052906; GO:0070901 34479 FUN_007979 67 49 49 101 82 ptg000002l:6771979-6775130 F4NUJ6 3.28e-25 tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5) Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog chytrid fungus) mitochondrial tRNA methylation [GO:0070901]; tRNA methylation [GO:0030488]; tRNA N1-guanine methylation [GO:0002939] GO:0002939; GO:0005634; GO:0005737; GO:0005759; GO:0008175; GO:0009019; GO:0030488; GO:0052906; GO:0070901 34480 FUN_020748 15 0 0 0 0 NA NA NA NA NA NA NA 34481 FUN_018233 153 564 255 817 558 NA NA NA NA NA NA NA 34482 FUN_022734 51 6 17 19 22 ptg000016l:12696994-12697880 P25291 1.46e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 34483 FUN_008040 86 74 91 76 118 NA NA NA NA NA NA NA 34484 FUN_036169 1063 1276 774 987 793 ptg000025l:15971569-15983195 Q28001 6e-48 Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) Bos taurus (Bovine) alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] GO:0006836; GO:0008021; GO:0015293; GO:0015804; GO:0015816; GO:0015820; GO:0015824; GO:0016020; GO:0030672; GO:0032328; GO:0035725; GO:0042995; GO:0098794 34485 FUN_008041 87 148 88 66 81 NA NA NA NA NA NA NA 34486 FUN_036162 0 11 0 2 5 NA NA NA NA NA NA NA 34487 FUN_036163 4586 4644 2354 3936 3323 NA NA NA NA NA NA NA 34488 FUN_036160 243 52 70 208 86 ptg000025l:15879985-15881290 Q1WK23 1.79e-40 Serine protease 23 (EC 3.4.21.-) Macaca mulatta (Rhesus macaque) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 34489 FUN_036161 25 37 4 125 68 ptg000025l:15890327-15891425 Q6AY61 2.98e-40 Serine protease 23 (EC 3.4.21.-) Rattus norvegicus (Rat) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 34490 FUN_036166 36520 30587 8575 27261 12517 ptg000025l:15929674-15941440 Q3MHL4 1.08e-50 Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0004013; GO:0005829; GO:0006730; GO:0033353; GO:0042470; GO:0051287 34491 FUN_036166 36520 30587 8575 27261 12517 ptg000025l:15929674-15941440 Q3MHL4 4.51e-29 Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0004013; GO:0005829; GO:0006730; GO:0033353; GO:0042470; GO:0051287 34492 FUN_036166 36520 30587 8575 27261 12517 ptg000025l:15929674-15941440 Q3MHL4 1.43e-26 Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0004013; GO:0005829; GO:0006730; GO:0033353; GO:0042470; GO:0051287 34493 FUN_036166 36520 30587 8575 27261 12517 ptg000025l:15929674-15941440 Q3MHL4 8.24e-24 Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0004013; GO:0005829; GO:0006730; GO:0033353; GO:0042470; GO:0051287 34494 FUN_036166 36520 30587 8575 27261 12517 ptg000025l:15929674-15941440 Q3MHL4 3.17e-22 Adenosylhomocysteinase (AdoHcyase) (EC 3.13.2.1) (S-adenosyl-L-homocysteine hydrolase) Bos taurus (Bovine) one-carbon metabolic process [GO:0006730]; S-adenosylmethionine cycle [GO:0033353] GO:0004013; GO:0005829; GO:0006730; GO:0033353; GO:0042470; GO:0051287 34495 FUN_036167 154 472 211 273 88 ptg000025l:15947778-15954940 Q28001 8.09e-28 Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17) Bos taurus (Bovine) alanine transport [GO:0032328]; glycine transport [GO:0015816]; leucine transport [GO:0015820]; neurotransmitter transport [GO:0006836]; neutral amino acid transport [GO:0015804]; proline transport [GO:0015824]; sodium ion transmembrane transport [GO:0035725] GO:0006836; GO:0008021; GO:0015293; GO:0015804; GO:0015816; GO:0015820; GO:0015824; GO:0016020; GO:0030672; GO:0032328; GO:0035725; GO:0042995; GO:0098794 34496 FUN_036164 16879 14229 14411 17919 19093 ptg000025l:15905272-15914313 Q5RC80 1.47e-47 RNA-binding protein 39 (RNA-binding motif protein 39) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mRNA processing [GO:0006397]; regulation of mRNA splicing, via spliceosome [GO:0048024]; RNA splicing [GO:0008380] GO:0003723; GO:0006397; GO:0008380; GO:0016607; GO:0032991; GO:0034451; GO:0048024; GO:0050733 34497 FUN_036165 3709 2824 725 2696 937 ptg000025l:15920870-15927267 D2I2M6 1.13e-31 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) Ailuropoda melanoleuca (Giant panda) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; GPI anchor biosynthetic process [GO:0006506] GO:0005793; GO:0005801; GO:0006506; GO:0006888; GO:0030145; GO:0033116; GO:0034235; GO:0062050; GO:0070971 34498 FUN_036165 3709 2824 725 2696 937 ptg000025l:15920870-15927267 D2I2M6 2.38e-26 Metallophosphoesterase 1 (EC 3.1.-.-) (Post-GPI attachment to proteins factor 5) Ailuropoda melanoleuca (Giant panda) endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; GPI anchor biosynthetic process [GO:0006506] GO:0005793; GO:0005801; GO:0006506; GO:0006888; GO:0030145; GO:0033116; GO:0034235; GO:0062050; GO:0070971 34499 FUN_008043 253 630 472 257 199 NA NA NA NA NA NA NA 34500 FUN_024477 112 100 25 104 130 NA NA NA NA NA NA NA 34501 FUN_008045 261 62 66 107 81 NA NA NA NA NA NA NA 34502 FUN_024475 76 44 60 201 41 ptg000018l:6800864-6805190 P20965 1.25e-26 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 34503 FUN_024475 76 44 60 201 41 ptg000018l:6800864-6805190 P20965 5.33e-26 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 34504 FUN_024475 76 44 60 201 41 ptg000018l:6800864-6805190 P20965 3.12e-25 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 34505 FUN_024475 76 44 60 201 41 ptg000018l:6800864-6805190 P20965 8.73e-25 Polyadenylate-binding protein 1-A (PABP-1-A) (Poly(A)-binding protein 1-A) (xPABP1-A) (Cytoplasmic poly(A)-binding protein 1-A) Xenopus laevis (African clawed frog) mRNA processing [GO:0006397]; mRNA stabilization [GO:0048255]; negative regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060212]; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [GO:1900153]; positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [GO:0060213]; RNA-mediated gene silencing [GO:0031047]; translation [GO:0006412] GO:0005737; GO:0005844; GO:0006397; GO:0006412; GO:0008143; GO:0031047; GO:0031370; GO:0043621; GO:0048255; GO:0060212; GO:0060213; GO:1900153 34506 FUN_008047 976 737 412 271 358 NA NA NA NA NA NA NA 34507 FUN_000109 7 0 11 2 18 ntLink_4:144120-145381 P35067 1.67e-80 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34508 FUN_000108 2 0 4 0 12 ntLink_4:140764-143046 P84239 8.17e-87 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34509 FUN_000104 2 0 3 0 17 ntLink_4:130873-131654 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34510 FUN_000107 2 0 7 0 7 ntLink_4:136794-140432 P35061 7.39e-76 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34511 FUN_000106 2 0 4 0 15 ntLink_4:134939-135720 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34512 FUN_000100 7 0 13 2 18 ntLink_4:123111-123874 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34513 FUN_000102 4 1 11 2 16 ntLink_4:127177-127940 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34514 FUN_014936 178 45 90 216 174 NA NA NA NA NA NA NA 34515 FUN_007779 405 160 86 292 0 NA NA NA NA NA NA NA 34516 FUN_007778 181 172 54 139 49 NA NA NA NA NA NA NA 34517 FUN_007777 549 623 850 1167 621 ptg000002l:4675011-4683677 D4A523 6.32e-44 NACHT, LRR and PYD domains-containing protein 3 (EC 3.6.4.-) Rattus norvegicus (Rat) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; acute inflammatory response [GO:0002526]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to virus [GO:0098586]; defense response to Gram-positive bacterium [GO:0050830]; defense response to virus [GO:0051607]; detection of biotic stimulus [GO:0009595]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; leukocyte migration involved in inflammatory response [GO:0002523]; negative regulation of acute inflammatory response [GO:0002674]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; NLRP3 inflammasome complex assembly [GO:0044546]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-13 production [GO:0032736]; positive regulation of interleukin-4 production [GO:0032753]; positive regulation of interleukin-5 production [GO:0032754]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T-helper 17 cell differentiation [GO:2000321]; positive regulation of T-helper 2 cell cytokine production [GO:2000553]; positive regulation of T-helper 2 cell differentiation [GO:0045630]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of type 2 immune response [GO:0002830]; protein homooligomerization [GO:0051260]; regulation of inflammatory response [GO:0050727]; response to ethanol [GO:0045471]; response to organic cyclic compound [GO:0014070] GO:0000139; GO:0002523; GO:0002526; GO:0002674; GO:0002720; GO:0002830; GO:0005524; GO:0005576; GO:0005634; GO:0005737; GO:0005739; GO:0005783; GO:0006919; GO:0006954; GO:0009595; GO:0014070; GO:0016020; GO:0016887; GO:0031021; GO:0032088; GO:0032691; GO:0032731; GO:0032736; GO:0032753; GO:0032754; GO:0035591; GO:0042802; GO:0043280; GO:0043531; GO:0043565; GO:0044546; GO:0045087; GO:0045471; GO:0045630; GO:0045944; GO:0050727; GO:0050728; GO:0050729; GO:0050830; GO:0051092; GO:0051260; GO:0051607; GO:0061702; GO:0070273; GO:0071222; GO:0071224; GO:0072559; GO:0098586; GO:0140297; GO:0140299; GO:1901223; GO:1901981; GO:2000321; GO:2000553 34518 FUN_007776 15 43 40 0 0 NA NA NA NA NA NA NA 34519 FUN_007775 2148 1584 1930 2615 3535 NA NA NA NA NA NA NA 34520 FUN_007774 1942 1392 1114 2067 1739 NA NA NA NA NA NA NA 34521 FUN_007773 351 463 178 353 266 NA NA NA NA NA NA NA 34522 FUN_007772 2757 1393 1154 1865 1626 NA NA NA NA NA NA NA 34523 FUN_007770 286 86 149 2659 2081 NA NA NA NA NA NA NA 34524 FUN_027218 2741 1715 1382 2305 2138 NA NA NA NA NA NA NA 34525 FUN_027219 1883 1861 1266 2184 1489 ptg000021l:1942661-1966001 Q7Z4T9 4.55e-36 Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1) Homo sapiens (Human) axonemal central apparatus assembly [GO:1904158]; cell differentiation [GO:0030154]; cilium movement [GO:0003341]; spermatogenesis [GO:0007283] GO:0003341; GO:0005739; GO:0005930; GO:0007283; GO:0030154; GO:0031514; GO:1904158 34526 FUN_027212 341 243 348 614 186 NA NA NA NA NA NA NA 34527 FUN_027213 128 234 149 138 195 NA NA NA NA NA NA NA 34528 FUN_027211 678 257 261 925 167 ptg000021l:1837348-1846216 B2RX12 3.17e-24 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multidrug resistance-associated protein 3) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; bile acid and bile salt transport [GO:0015721]; canalicular bile acid transport [GO:0015722]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006855; GO:0008559; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0015722; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0055085; GO:0071714; GO:0071716; GO:0098656 34529 FUN_027214 0 0 0 6 0 NA NA NA NA NA NA NA 34530 FUN_027215 4218 1429 911 1305 1936 ptg000021l:1890023-1916874 Q8CG09 4.94e-24 Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter) Rattus norvegicus (Rat) carboxylic acid transmembrane transport [GO:1905039]; cell chemotaxis [GO:0060326]; cellular response to amyloid-beta [GO:1904646]; cobalamin metabolic process [GO:0009235]; cobalamin transport [GO:0015889]; export across plasma membrane [GO:0140115]; glutathione transmembrane transport [GO:0034775]; leukotriene transport [GO:0071716]; long-chain fatty acid import across plasma membrane [GO:0015911]; negative regulation of cell death [GO:0060548]; negative regulation of neuron death [GO:1901215]; phospholipid efflux [GO:0033700]; phospholipid translocation [GO:0045332]; positive regulation of cell migration [GO:0030335]; positive regulation of inflammatory response [GO:0050729]; response to oxidative stress [GO:0006979]; response to xenobiotic stimulus [GO:0009410]; sphingolipid translocation [GO:0099039]; transepithelial transport [GO:0070633]; transmembrane transport [GO:0055085]; xenobiotic detoxification by transmembrane export across the plasma membrane [GO:1990961]; xenobiotic transport [GO:0042908]; xenobiotic transport across blood-brain barrier [GO:1990962] GO:0005324; GO:0005524; GO:0005737; GO:0005886; GO:0006979; GO:0008559; GO:0009235; GO:0009410; GO:0009925; GO:0015420; GO:0015431; GO:0015562; GO:0015889; GO:0015911; GO:0016020; GO:0016323; GO:0016324; GO:0016328; GO:0016491; GO:0016887; GO:0030335; GO:0033700; GO:0034040; GO:0034634; GO:0034775; GO:0042626; GO:0042887; GO:0042908; GO:0042910; GO:0045332; GO:0046943; GO:0050729; GO:0055085; GO:0060326; GO:0060548; GO:0070633; GO:0071716; GO:0099039; GO:0140115; GO:0140359; GO:1901215; GO:1904646; GO:1905039; GO:1990961; GO:1990962 34531 FUN_005680 0 0 2 0 22 NA NA NA NA NA NA NA 34532 FUN_005683 0 0 6 0 7 NA NA NA NA NA NA NA 34533 FUN_005682 0 0 5 0 12 NA NA NA NA NA NA NA 34534 FUN_005687 0 0 4 0 8 NA NA NA NA NA NA NA 34535 FUN_005686 1 0 5 0 8 NA NA NA NA NA NA NA 34536 FUN_005689 65 0 0 76 97 NA NA NA NA NA NA NA 34537 FUN_005688 23 16 5 46 9 NA NA NA NA NA NA NA 34538 FUN_014938 19 109 15 181 185 NA NA NA NA NA NA NA 34539 FUN_026207 71 112 91 193 262 NA NA NA NA NA NA NA 34540 FUN_028660 384 10 128 155 115 NA NA NA NA NA NA NA 34541 FUN_035333 266 172 215 116 123 NA NA NA NA NA NA NA 34542 FUN_028667 0 10 0 0 0 NA NA NA NA NA NA NA 34543 FUN_003504 4 0 12 6 26 NA NA NA NA NA NA NA 34544 FUN_006798 3419 3095 2118 4152 2425 NA NA NA NA NA NA NA 34545 FUN_006799 4197 4874 2511 3977 2489 NA NA NA NA NA NA NA 34546 FUN_028664 0 0 21 13 0 NA NA NA NA NA NA NA 34547 FUN_008338 3151 2541 2509 5505 4582 ptg000002l:10517985-10557638 B8V7S0 3.09e-85 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 34548 FUN_008339 248 74 31 68 37 NA NA NA NA NA NA NA 34549 FUN_006792 84 2 97 9 369 NA NA NA NA NA NA NA 34550 FUN_006793 32 20 23 53 23 ptg000001l:16692498-16693518 P05363 4.7e-24 Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) Bos taurus (Bovine) positive regulation of flagellated sperm motility [GO:1902093]; regulation of uterine smooth muscle contraction [GO:0070472] GO:0004995; GO:0005886; GO:0016497; GO:0061827; GO:0070472; GO:0097225; GO:1902093 34551 FUN_006790 3816 3940 2625 4795 2242 ptg000001l:16587658-16608887 P22607 1.64e-43 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 34552 FUN_006790 3816 3940 2625 4795 2242 ptg000001l:16587658-16608887 P22607 1.64e-43 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 34553 FUN_008335 0 0 14 15 0 NA NA NA NA NA NA NA 34554 FUN_006796 5031 3006 1972 7969 3918 NA NA NA NA NA NA NA 34555 FUN_008333 1022 748 650 1426 841 NA NA NA NA NA NA NA 34556 FUN_006794 0 0 9 0 51 NA NA NA NA NA NA NA 34557 FUN_006795 63 147 24 260 120 NA NA NA NA NA NA NA 34558 FUN_003427 17 0 0 14 0 NA NA NA NA NA NA NA 34559 FUN_016939 0 0 0 9 0 NA NA NA NA NA NA NA 34560 FUN_016938 6 51 16 30 15 NA NA NA NA NA NA NA 34561 FUN_003426 0 0 0 0 11 NA NA NA NA NA NA NA 34562 FUN_016931 12 33 182 189 111 NA NA NA NA NA NA NA 34563 FUN_016930 0 48 29 75 110 NA NA NA NA NA NA NA 34564 FUN_016937 1 0 0 12 1 NA NA NA NA NA NA NA 34565 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 3.4e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34566 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 1.09e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34567 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 1.93e-63 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34568 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 3.62e-57 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34569 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 1.93e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34570 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 2.66e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34571 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 7.75e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34572 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 3.28e-45 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34573 FUN_016936 0 3 1 57 0 ptg000011l:9112456-9115155 Q96AY4 5.35e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34574 FUN_016935 0 41 12 102 44 NA NA NA NA NA NA NA 34575 FUN_003453 170 186 711 902 598 ntLink_8:11579544-11594917 A0A1B4XBH3 7.39e-152 Highly reducing polyketide synthase sdnO (EC 2.3.1.-) (Sordarin/hypoxysordarin biosynthesis cluster protein O) Sordaria araneosa (Pleurage araneosa) antibiotic biosynthetic process [GO:0017000]; organic substance biosynthetic process [GO:1901576] GO:0016491; GO:0016746; GO:0017000; GO:0031177; GO:1901576 34576 FUN_003450 45 30 197 38 34 ntLink_8:11545733-11549729 Q0EEE2 1.81e-56 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 34577 FUN_004488 48 143 12 221 121 NA NA NA NA NA NA NA 34578 FUN_004489 250 251 124 230 137 NA NA NA NA NA NA NA 34579 FUN_003454 1179 30 13 38 19 NA NA NA NA NA NA NA 34580 FUN_004484 685 464 266 414 521 ntLink_8:23688837-23703850 P0CT39 9.83e-63 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 34581 FUN_004485 545 317 548 385 518 NA NA NA NA NA NA NA 34582 FUN_004480 0 16 0 0 31 NA NA NA NA NA NA NA 34583 FUN_015044 340 317 200 446 732 NA NA NA NA NA NA NA 34584 FUN_004483 0 0 40 0 52 ntLink_8:23683767-23685523 Q24352 1.07e-21 Gamma-aminobutyric acid receptor alpha-like (GABA(A) receptor alpha-like and glycine receptor-like subunit of Drosophila) (GRD) Drosophila melanogaster (Fruit fly) chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; negative regulation of neuronal action potential [GO:1904456]; nervous system process [GO:0050877]; regulation of circadian rhythm [GO:0042752]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004890; GO:0005231; GO:0005261; GO:0005886; GO:0006811; GO:0007165; GO:0007268; GO:0015276; GO:0016020; GO:0016933; GO:0022851; GO:0022852; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0042752; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0060012; GO:1902476; GO:1904315; GO:1904456 34585 FUN_015045 806 251 261 599 610 ptg000009l:5598399-5607961 O95294 9.97e-24 RasGAP-activating-like protein 1 (RAS protein activator like 1) (Ras GTPase-activating-like protein) Homo sapiens (Human) cell differentiation [GO:0030154]; cellular response to calcium ion [GO:0071277]; intracellular signal transduction [GO:0035556]; negative regulation of Ras protein signal transduction [GO:0046580]; positive regulation of dendrite extension [GO:1903861]; regulation of GTPase activity [GO:0043087]; signal transduction [GO:0007165] GO:0005096; GO:0005543; GO:0005829; GO:0007165; GO:0030154; GO:0035556; GO:0043087; GO:0046580; GO:0046872; GO:0071277; GO:1903861 34586 FUN_008753 1100 737 743 1001 1292 NA NA NA NA NA NA NA 34587 FUN_003421 0 0 0 0 26 NA NA NA NA NA NA NA 34588 FUN_015042 4728 3446 2064 3748 3760 ptg000009l:5567273-5579391 P22059 4.1e-35 Oxysterol-binding protein 1 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; ceramide transport [GO:0035627]; intracellular cholesterol transport [GO:0032367]; phospholipid transport [GO:0015914]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of secretory granule organization [GO:1904411]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; sphingomyelin biosynthetic process [GO:0006686]; sterol transport [GO:0015918] GO:0000139; GO:0005654; GO:0005730; GO:0005737; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0006686; GO:0006699; GO:0008142; GO:0015248; GO:0015914; GO:0015918; GO:0016020; GO:0019904; GO:0030054; GO:0032367; GO:0032934; GO:0035627; GO:0035774; GO:0042531; GO:0043231; GO:0048471; GO:0070273; GO:0097038; GO:0120015; GO:1904411 34589 FUN_015042 4728 3446 2064 3748 3760 ptg000009l:5567273-5579391 P22059 4.1e-35 Oxysterol-binding protein 1 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; ceramide transport [GO:0035627]; intracellular cholesterol transport [GO:0032367]; phospholipid transport [GO:0015914]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of secretory granule organization [GO:1904411]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; sphingomyelin biosynthetic process [GO:0006686]; sterol transport [GO:0015918] GO:0000139; GO:0005654; GO:0005730; GO:0005737; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0006686; GO:0006699; GO:0008142; GO:0015248; GO:0015914; GO:0015918; GO:0016020; GO:0019904; GO:0030054; GO:0032367; GO:0032934; GO:0035627; GO:0035774; GO:0042531; GO:0043231; GO:0048471; GO:0070273; GO:0097038; GO:0120015; GO:1904411 34590 FUN_015042 4728 3446 2064 3748 3760 ptg000009l:5567273-5579391 P22059 7.06e-31 Oxysterol-binding protein 1 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; ceramide transport [GO:0035627]; intracellular cholesterol transport [GO:0032367]; phospholipid transport [GO:0015914]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of secretory granule organization [GO:1904411]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; sphingomyelin biosynthetic process [GO:0006686]; sterol transport [GO:0015918] GO:0000139; GO:0005654; GO:0005730; GO:0005737; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0006686; GO:0006699; GO:0008142; GO:0015248; GO:0015914; GO:0015918; GO:0016020; GO:0019904; GO:0030054; GO:0032367; GO:0032934; GO:0035627; GO:0035774; GO:0042531; GO:0043231; GO:0048471; GO:0070273; GO:0097038; GO:0120015; GO:1904411 34591 FUN_015042 4728 3446 2064 3748 3760 ptg000009l:5567273-5579391 P22059 5.56e-24 Oxysterol-binding protein 1 Homo sapiens (Human) bile acid biosynthetic process [GO:0006699]; ceramide transport [GO:0035627]; intracellular cholesterol transport [GO:0032367]; phospholipid transport [GO:0015914]; positive regulation of insulin secretion involved in cellular response to glucose stimulus [GO:0035774]; positive regulation of secretory granule organization [GO:1904411]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; sphingomyelin biosynthetic process [GO:0006686]; sterol transport [GO:0015918] GO:0000139; GO:0005654; GO:0005730; GO:0005737; GO:0005789; GO:0005794; GO:0005802; GO:0005829; GO:0005886; GO:0006686; GO:0006699; GO:0008142; GO:0015248; GO:0015914; GO:0015918; GO:0016020; GO:0019904; GO:0030054; GO:0032367; GO:0032934; GO:0035627; GO:0035774; GO:0042531; GO:0043231; GO:0048471; GO:0070273; GO:0097038; GO:0120015; GO:1904411 34592 FUN_015043 568 191 212 326 364 NA NA NA NA NA NA NA 34593 FUN_008480 83 11 17 70 10 ptg000002l:12072861-12077284 Q9I830 2.49e-48 Potassium voltage-gated channel subfamily A member 2 (Shaker-related potassium channel tsha1) (Trout shaker 1) (Voltage-gated potassium channel subunit Kv1.2) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) neuronal action potential [GO:0019228]; potassium ion transmembrane transport [GO:0071805]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765] GO:0005249; GO:0005251; GO:0005886; GO:0008076; GO:0019228; GO:0034765; GO:0044224; GO:0051260; GO:0071805 34594 FUN_008481 39 0 56 50 39 ptg000002l:12084039-12086664 P17972 1.01e-32 Potassium voltage-gated channel protein Shaw (Shaw2) Drosophila melanogaster (Fruit fly) potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homooligomerization [GO:0051260]; regulation of ion transmembrane transport [GO:0034765]; sleep [GO:0030431] GO:0005249; GO:0005251; GO:0005886; GO:0006813; GO:0008076; GO:0016020; GO:0022843; GO:0030424; GO:0030431; GO:0032590; GO:0032809; GO:0034765; GO:0051260; GO:0071805 34595 FUN_008482 190 163 134 250 69 NA NA NA NA NA NA NA 34596 FUN_008484 2132 1485 1443 1982 1988 NA NA NA NA NA NA NA 34597 FUN_008485 41 26 9 11 18 ptg000002l:12109720-12111187 Q9UJA9 5.3e-83 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Homo sapiens (Human) cell communication [GO:0007154] GO:0000210; GO:0005576; GO:0005886; GO:0007154; GO:0008270 34598 FUN_008486 83 12 37 53 45 ptg000002l:12115170-12119448 Q6R5J2 0 Protein dispatched homolog 1 (Protein chameleon) Danio rerio (Zebrafish) (Brachydanio rerio) adenohypophysis development [GO:0021984]; animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; blood circulation [GO:0008015]; embryonic cranial skeleton morphogenesis [GO:0048701]; inner ear development [GO:0048839]; muscle cell fate specification [GO:0042694]; retinal ganglion cell axon guidance [GO:0031290]; skeletal muscle tissue development [GO:0007519]; smoothened signaling pathway [GO:0007224]; transmembrane transport [GO:0055085] GO:0007224; GO:0007519; GO:0008015; GO:0009887; GO:0009952; GO:0016020; GO:0021984; GO:0022857; GO:0031290; GO:0042694; GO:0048701; GO:0048839; GO:0055085; GO:1904680 34599 FUN_008487 538 426 495 673 592 NA NA NA NA NA NA NA 34600 FUN_006424 2409 2840 1331 2204 1159 NA NA NA NA NA NA NA 34601 FUN_008489 5277 5314 3193 4703 2634 NA NA NA NA NA NA NA 34602 FUN_006427 2426 1541 1437 1673 1359 NA NA NA NA NA NA NA 34603 FUN_006420 20 10 5 14 47 NA NA NA NA NA NA NA 34604 FUN_006421 201 226 64 244 193 ptg000001l:12269412-12275019 A7RS11 3e-31 Histone PARylation factor 1 Nematostella vectensis (Starlet sea anemone) cellular response to DNA damage stimulus [GO:0006974]; regulation of protein ADP-ribosylation [GO:0010835] GO:0005634; GO:0005694; GO:0006974; GO:0010835; GO:0042393; GO:0072572 34605 FUN_006422 338 585 279 345 223 NA NA NA NA NA NA NA 34606 FUN_006423 198 182 73 108 53 NA NA NA NA NA NA NA 34607 FUN_033488 1113 1109 874 1180 982 NA NA NA NA NA NA NA 34608 FUN_033489 0 0 0 0 10 NA NA NA NA NA NA NA 34609 FUN_033482 4 0 8 0 10 NA NA NA NA NA NA NA 34610 FUN_033487 1737 1841 529 1018 257 NA NA NA NA NA NA NA 34611 FUN_033485 202 12 0 2 0 NA NA NA NA NA NA NA 34612 FUN_040350 236 234 653 121 76 NA NA NA NA NA NA NA 34613 FUN_004157 1622 1746 444 796 992 ntLink_8:19905962-19910016 Q12834 1.15e-29 Cell division cycle protein 20 homolog (p55CDC) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005819; GO:0005829; GO:0007064; GO:0007094; GO:0007346; GO:0007399; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0030154; GO:0031145; GO:0031915; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0051445; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 34614 FUN_004157 1622 1746 444 796 992 ntLink_8:19905962-19910016 Q12834 6.18e-25 Cell division cycle protein 20 homolog (p55CDC) Homo sapiens (Human) anaphase-promoting complex-dependent catabolic process [GO:0031145]; cell differentiation [GO:0030154]; cell division [GO:0051301]; mitotic sister chromatid cohesion [GO:0007064]; mitotic spindle assembly [GO:0090307]; mitotic spindle assembly checkpoint signaling [GO:0007094]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; nervous system development [GO:0007399]; positive regulation of anaphase-promoting complex-dependent catabolic process [GO:1905786]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of synapse maturation [GO:0090129]; positive regulation of synaptic plasticity [GO:0031915]; positive regulation of ubiquitin protein ligase activity [GO:1904668]; protein ubiquitination [GO:0016567]; regulation of dendrite development [GO:0050773]; regulation of meiotic cell cycle [GO:0051445]; regulation of meiotic nuclear division [GO:0040020]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005654; GO:0005680; GO:0005813; GO:0005819; GO:0005829; GO:0007064; GO:0007094; GO:0007346; GO:0007399; GO:0008022; GO:0008284; GO:0010997; GO:0016567; GO:0019899; GO:0030154; GO:0031145; GO:0031915; GO:0033597; GO:0040020; GO:0042826; GO:0048471; GO:0050773; GO:0051301; GO:0051444; GO:0051445; GO:0090129; GO:0090307; GO:1904668; GO:1905786; GO:1990757 34615 FUN_004154 1276 429 915 1196 216 NA NA NA NA NA NA NA 34616 FUN_010474 1 17 0 0 5 NA NA NA NA NA NA NA 34617 FUN_040355 27 0 0 0 24 NA NA NA NA NA NA NA 34618 FUN_010477 0 0 90 0 9 NA NA NA NA NA NA NA 34619 FUN_004158 902 1212 540 1174 638 ntLink_8:19910282-19911520 A6QLY2 1.97e-42 Glutathione peroxidase 7 (GPx-7) (GSHPx-7) (EC 1.11.1.9) Bos taurus (Bovine) response to oxidative stress [GO:0006979] GO:0004096; GO:0004601; GO:0004602; GO:0005576; GO:0005783; GO:0006979 34620 FUN_004159 8 2 9 31 55 NA NA NA NA NA NA NA 34621 FUN_030035 0 0 0 26 0 NA NA NA NA NA NA NA 34622 FUN_031519 349 325 350 289 260 NA NA NA NA NA NA NA 34623 FUN_043576 56 0 0 114 54 NA NA NA NA NA NA NA 34624 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 9.23e-50 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34625 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 3.58e-43 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34626 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 3.19e-37 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34627 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 1.46e-34 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34628 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 4.43e-29 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34629 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 1.53e-23 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34630 FUN_028299 2592 1541 1596 2767 2607 ptg000021l:18008482-18034237 O75179 3.52e-22 Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) Homo sapiens (Human) blood vessel maturation [GO:0001955]; defense response to bacterium [GO:0042742]; innate immune response [GO:0045087]; negative regulation of smooth muscle cell differentiation [GO:0051151]; positive regulation of cell cycle [GO:0045787]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of MDA-5 signaling pathway [GO:1900245]; positive regulation of RIG-I signaling pathway [GO:1900246]; regulation of DNA replication [GO:0006275] GO:0000785; GO:0001673; GO:0001955; GO:0003682; GO:0003723; GO:0005634; GO:0005654; GO:0005737; GO:0006275; GO:0016020; GO:0031965; GO:0042742; GO:0043123; GO:0045087; GO:0045787; GO:0051151; GO:1900087; GO:1900245; GO:1900246 34631 FUN_028298 1049 1380 701 866 890 NA NA NA NA NA NA NA 34632 FUN_044303 2 0 11 1 67 NA NA NA NA NA NA NA 34633 FUN_003501 0 0 15 17 14 NA NA NA NA NA NA NA 34634 FUN_028293 1533 835 555 1138 952 NA NA NA NA NA NA NA 34635 FUN_028292 127 124 44 91 105 NA NA NA NA NA NA NA 34636 FUN_028291 346 254 280 330 384 NA NA NA NA NA NA NA 34637 FUN_028290 0 26 0 0 0 NA NA NA NA NA NA NA 34638 FUN_028297 62 24 0 46 0 NA NA NA NA NA NA NA 34639 FUN_028296 866 197 76 794 16 NA NA NA NA NA NA NA 34640 FUN_028295 14 634 258 416 554 NA NA NA NA NA NA NA 34641 FUN_034281 23996 43755 16234 27179 20880 NA NA NA NA NA NA NA 34642 FUN_034280 1107 788 501 804 823 NA NA NA NA NA NA NA 34643 FUN_034283 1044 374 453 688 1801 NA NA NA NA NA NA NA 34644 FUN_044302 4 4 6 0 47 NA NA NA NA NA NA NA 34645 FUN_034285 0 0 0 9 0 NA NA NA NA NA NA NA 34646 FUN_034284 2089 2023 1128 1566 1138 NA NA NA NA NA NA NA 34647 FUN_034287 926 1104 437 1194 1103 NA NA NA NA NA NA NA 34648 FUN_034286 1465 1140 955 1300 1984 NA NA NA NA NA NA NA 34649 FUN_034289 351 159 228 213 266 NA NA NA NA NA NA NA 34650 FUN_034288 2000 1123 952 1578 1892 NA NA NA NA NA NA NA 34651 FUN_024052 92 135 110 175 262 NA NA NA NA NA NA NA 34652 FUN_030030 387 91 133 172 426 NA NA NA NA NA NA NA 34653 FUN_003503 1 0 0 0 26 NA NA NA NA NA NA NA 34654 FUN_044300 24 41 58 61 170 NA NA NA NA NA NA NA 34655 FUN_002415 0 0 628 3 0 NA NA NA NA NA NA NA 34656 FUN_011700 0 0 19 70 0 NA NA NA NA NA NA NA 34657 FUN_011703 1815 1000 858 1298 707 NA NA NA NA NA NA NA 34658 FUN_002416 0 0 52 0 0 NA NA NA NA NA NA NA 34659 FUN_011705 73 18 51 85 250 NA NA NA NA NA NA NA 34660 FUN_011704 1127 994 774 920 1166 NA NA NA NA NA NA NA 34661 FUN_011707 2294 3169 1182 1726 1210 NA NA NA NA NA NA NA 34662 FUN_011706 4047 1581 2000 3171 2204 ptg000008l:381670-386219 Q8BYR2 2.37e-149 Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) Mus musculus (Mouse) cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; hippo signaling [GO:0035329]; hormone-mediated signaling pathway [GO:0009755]; inner cell mass cell fate commitment [GO:0001827]; inner cell mass cellular morphogenesis [GO:0001828]; intracellular signal transduction [GO:0035556]; keratinocyte differentiation [GO:0030216]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of organ growth [GO:0046620]; regulation of protein-containing complex assembly [GO:0043254]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; sister chromatid segregation [GO:0000819] GO:0000082; GO:0000086; GO:0000287; GO:0000819; GO:0000922; GO:0001827; GO:0001828; GO:0004674; GO:0005524; GO:0005737; GO:0005815; GO:0006468; GO:0008104; GO:0009755; GO:0017015; GO:0018105; GO:0019901; GO:0030216; GO:0030331; GO:0030496; GO:0030833; GO:0033138; GO:0033146; GO:0035329; GO:0035556; GO:0043065; GO:0043254; GO:0045736; GO:0046620; GO:0051220; GO:0051301; GO:0060644; GO:0090090; GO:0106310; GO:1900181; GO:2000058 34663 FUN_011706 4047 1581 2000 3171 2204 ptg000008l:381670-386219 Q8BYR2 6.46e-30 Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) Mus musculus (Mouse) cell division [GO:0051301]; cytoplasmic sequestering of protein [GO:0051220]; G1/S transition of mitotic cell cycle [GO:0000082]; G2/M transition of mitotic cell cycle [GO:0000086]; hippo signaling [GO:0035329]; hormone-mediated signaling pathway [GO:0009755]; inner cell mass cell fate commitment [GO:0001827]; inner cell mass cellular morphogenesis [GO:0001828]; intracellular signal transduction [GO:0035556]; keratinocyte differentiation [GO:0030216]; mammary gland epithelial cell differentiation [GO:0060644]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of protein localization to nucleus [GO:1900181]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of apoptotic process [GO:0043065]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; protein localization [GO:0008104]; protein phosphorylation [GO:0006468]; regulation of actin filament polymerization [GO:0030833]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of organ growth [GO:0046620]; regulation of protein-containing complex assembly [GO:0043254]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; sister chromatid segregation [GO:0000819] GO:0000082; GO:0000086; GO:0000287; GO:0000819; GO:0000922; GO:0001827; GO:0001828; GO:0004674; GO:0005524; GO:0005737; GO:0005815; GO:0006468; GO:0008104; GO:0009755; GO:0017015; GO:0018105; GO:0019901; GO:0030216; GO:0030331; GO:0030496; GO:0030833; GO:0033138; GO:0033146; GO:0035329; GO:0035556; GO:0043065; GO:0043254; GO:0045736; GO:0046620; GO:0051220; GO:0051301; GO:0060644; GO:0090090; GO:0106310; GO:1900181; GO:2000058 34664 FUN_000480 0 0 6 0 26 ntLink_6:3483022-3484217 O93430 2.75e-24 Glycine receptor subunit alphaZ1 Danio rerio (Zebrafish) (Brachydanio rerio) cellular response to amino acid stimulus [GO:0071230]; cellular response to ethanol [GO:0071361]; cellular response to zinc ion [GO:0071294]; central nervous system development [GO:0007417]; chemical synaptic transmission [GO:0007268]; chloride transmembrane transport [GO:1902476]; ion transmembrane transport [GO:0034220]; ion transport [GO:0006811]; nervous system process [GO:0050877]; neuropeptide signaling pathway [GO:0007218]; regulation of membrane potential [GO:0042391]; regulation of neuron differentiation [GO:0045664]; response to amino acid [GO:0043200]; signal transduction [GO:0007165]; synaptic transmission, glycinergic [GO:0060012] GO:0004888; GO:0005231; GO:0005886; GO:0006811; GO:0007165; GO:0007218; GO:0007268; GO:0007417; GO:0008270; GO:0016594; GO:0016933; GO:0016934; GO:0030425; GO:0030594; GO:0034220; GO:0034707; GO:0042391; GO:0043005; GO:0043200; GO:0043204; GO:0045202; GO:0045211; GO:0045664; GO:0050877; GO:0060012; GO:0071230; GO:0071294; GO:0071361; GO:1902476; GO:1904315 34665 FUN_000481 11 0 0 0 0 NA NA NA NA NA NA NA 34666 FUN_000482 80 24 52 39 60 ntLink_6:3497384-3505176 Q9Z2D5 9.67e-30 Neuropeptide Y receptor type 2 (NPY2-R) (NPY-Y2 receptor) (Y2 receptor) Cavia porcellus (Guinea pig) NA GO:0004983; GO:0005886 34667 FUN_000483 1514 1260 932 1526 856 NA NA NA NA NA NA NA 34668 FUN_000485 15 4 6 10 0 NA NA NA NA NA NA NA 34669 FUN_000486 0 29 19 57 27 NA NA NA NA NA NA NA 34670 FUN_000487 39 0 0 57 21 NA NA NA NA NA NA NA 34671 FUN_006499 0 0 0 50 62 NA NA NA NA NA NA NA 34672 FUN_035888 9839 11686 6119 7843 5247 NA NA NA NA NA NA NA 34673 FUN_035889 1214 1332 858 1137 878 NA NA NA NA NA NA NA 34674 FUN_035885 2210 3237 2524 4995 2836 ptg000025l:12956675-12972778 Q6GQX6 8.21e-38 Ankyrin repeat and SAM domain-containing protein 6 (SamCystin) (Sterile alpha motif domain-containing protein 6) (SAM domain-containing protein 6) Mus musculus (Mouse) determination of left/right symmetry [GO:0007368]; heart development [GO:0007507]; in utero embryonic development [GO:0001701]; kidney development [GO:0001822] GO:0001701; GO:0001822; GO:0005737; GO:0007368; GO:0007507; GO:0042802; GO:0097543 34675 FUN_035886 783 648 524 625 883 NA NA NA NA NA NA NA 34676 FUN_035887 778 1187 557 379 314 NA NA NA NA NA NA NA 34677 FUN_035880 1488 764 411 1860 873 ptg000025l:12862691-12905409 Q8MH63 2.86e-41 Putative L-type amino acid transporter 1-like protein MLAS (hLAT1 3-transmembrane protein MLAS) (hLAT1 3TM MLAS) Homo sapiens (Human) NA GO:0015179; GO:0016020 34678 FUN_035880 1488 764 411 1860 873 ptg000025l:12862691-12905409 Q8MH63 1.55e-32 Putative L-type amino acid transporter 1-like protein MLAS (hLAT1 3-transmembrane protein MLAS) (hLAT1 3TM MLAS) Homo sapiens (Human) NA GO:0015179; GO:0016020 34679 FUN_035880 1488 764 411 1860 873 ptg000025l:12862691-12905409 Q8MH63 2.44e-32 Putative L-type amino acid transporter 1-like protein MLAS (hLAT1 3-transmembrane protein MLAS) (hLAT1 3TM MLAS) Homo sapiens (Human) NA GO:0015179; GO:0016020 34680 FUN_035882 61 46 15 47 87 ptg000025l:12927793-12935684 P82251 7.87e-40 b(0,+)-type amino acid transporter 1 (b(0,+)AT1) (Glycoprotein-associated amino acid transporter b0,+AT1) (Solute carrier family 7 member 9) Homo sapiens (Human) L-cystine transport [GO:0015811]; neutral amino acid transport [GO:0015804]; protein-containing complex assembly [GO:0065003] GO:0005886; GO:0015175; GO:0015179; GO:0015184; GO:0015804; GO:0015811; GO:0016324; GO:0031526; GO:0042605; GO:0065003 34681 FUN_035883 6104 6236 4574 4921 2804 NA NA NA NA NA NA NA 34682 FUN_043199 112 51 49 37 77 ptg000047l:5335402-5339669 P97402 3.04e-61 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase) Mus musculus (Mouse) maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; post-transcriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0005794; GO:0006486; GO:0007179; GO:0008109; GO:0008284; GO:0008375; GO:0010608; GO:0010718; GO:0010812; GO:0030335; GO:0034116; GO:0036438; GO:0051897; GO:0070374 34683 FUN_017005 489 1087 511 593 424 NA NA NA NA NA NA NA 34684 FUN_043193 605 407 316 419 508 NA NA NA NA NA NA NA 34685 FUN_043192 4390 5636 2444 4816 3868 NA NA NA NA NA NA NA 34686 FUN_043191 926 272 563 397 222 NA NA NA NA NA NA NA 34687 FUN_043190 477 345 246 360 205 ptg000047l:5200665-5201226 Q1LUI2 2.63e-73 5'-deoxynucleotidase HDDC2 (EC 3.1.3.89) (HD domain-containing protein 2) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0002953; GO:0046872 34688 FUN_043197 246 36 102 180 175 ptg000047l:5316432-5326957 P97402 1.18e-56 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) (Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase) Mus musculus (Mouse) maintenance of lens transparency [GO:0036438]; negative regulation of cell-substrate adhesion [GO:0010812]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of protein kinase B signaling [GO:0051897]; post-transcriptional regulation of gene expression [GO:0010608]; protein glycosylation [GO:0006486]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0000139; GO:0005794; GO:0006486; GO:0007179; GO:0008109; GO:0008284; GO:0008375; GO:0010608; GO:0010718; GO:0010812; GO:0030335; GO:0034116; GO:0036438; GO:0051897; GO:0070374 34689 FUN_043196 0 6 0 3 6 NA NA NA NA NA NA NA 34690 FUN_043195 1678 996 1349 1473 702 NA NA NA NA NA NA NA 34691 FUN_043194 18 0 0 0 12 NA NA NA NA NA NA NA 34692 FUN_044221 22 82 15 54 147 NA NA NA NA NA NA NA 34693 FUN_011779 1511 1034 1397 2345 2323 ptg000008l:1316877-1388217 P10394 2.28e-86 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 34694 FUN_011779 1511 1034 1397 2345 2323 ptg000008l:1316877-1388217 P10394 7.49e-37 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 34695 FUN_013419 3407 3214 1831 3819 3402 NA NA NA NA NA NA NA 34696 FUN_013418 103 328 98 413 155 NA NA NA NA NA NA NA 34697 FUN_013412 1084 2067 549 969 309 NA NA NA NA NA NA NA 34698 FUN_013411 756 343 412 307 149 NA NA NA NA NA NA NA 34699 FUN_013410 78 22 79 35 178 NA NA NA NA NA NA NA 34700 FUN_013417 11 117 45 65 42 NA NA NA NA NA NA NA 34701 FUN_013415 0 75 82 65 297 NA NA NA NA NA NA NA 34702 FUN_013414 1109 645 512 666 464 NA NA NA NA NA NA NA 34703 FUN_015718 0 117 0 0 0 NA NA NA NA NA NA NA 34704 FUN_022232 0 16 18 0 0 NA NA NA NA NA NA NA 34705 FUN_015715 0 16 0 0 0 NA NA NA NA NA NA NA 34706 FUN_015712 0 19 98 74 0 NA NA NA NA NA NA NA 34707 FUN_015713 64 14 7 13 29 NA NA NA NA NA NA NA 34708 FUN_015711 199 75 95 90 88 NA NA NA NA NA NA NA 34709 FUN_016168 0 0 4 0 28 NA NA NA NA NA NA NA 34710 FUN_042240 96 0 21 16 197 NA NA NA NA NA NA NA 34711 FUN_016161 3379 1843 1321 2024 1925 ptg000010l:2250314-2262423 P97480 5.25e-27 Eyes absent homolog 3 (EC 3.1.3.48) Mus musculus (Mouse) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; double-strand break repair [GO:0006302]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; positive regulation of DNA repair [GO:0045739]; protein dephosphorylation [GO:0006470]; response to ionizing radiation [GO:0010212] GO:0003682; GO:0004725; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0005813; GO:0006302; GO:0006325; GO:0006470; GO:0008138; GO:0010212; GO:0030154; GO:0045739; GO:0046872; GO:0048856; GO:0140793; GO:2001240 34712 FUN_042244 3 0 0 14 17 NA NA NA NA NA NA NA 34713 FUN_016165 3095 2558 1630 2292 1845 ptg000010l:2286883-2287962 Q5R833 4.22e-32 Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Hotdog-fold thioesterase superfamily member 2) (Palmitoyl-CoA hydrolase) (EC 3.1.2.2) (Thioesterase superfamily member 2) (THEM2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed] Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid metabolic process [GO:0006629] GO:0005634; GO:0005739; GO:0005819; GO:0005829; GO:0006629; GO:0016290; GO:0102991 34714 FUN_016166 3641 2419 1316 3126 2769 NA NA NA NA NA NA NA 34715 FUN_016167 1721 1194 667 1125 857 NA NA NA NA NA NA NA 34716 FUN_023072 4604 2005 2444 5230 4404 NA NA NA NA NA NA NA 34717 FUN_023073 46380 31560 27042 51031 36457 NA NA NA NA NA NA NA 34718 FUN_023071 164 52 121 252 124 NA NA NA NA NA NA NA 34719 FUN_023076 1361 959 1040 1352 1276 NA NA NA NA NA NA NA 34720 FUN_023077 12 0 0 0 17 NA NA NA NA NA NA NA 34721 FUN_023074 809 310 657 688 532 ptg000017l:3283744-3293484 Q8BZW8 5.55e-58 NHL repeat-containing protein 2 Mus musculus (Mouse) NA GO:0005829 34722 FUN_023074 809 310 657 688 532 ptg000017l:3283744-3293484 Q8BZW8 6.24e-24 NHL repeat-containing protein 2 Mus musculus (Mouse) NA GO:0005829 34723 FUN_023075 3998 1713 1680 1956 1262 NA NA NA NA NA NA NA 34724 FUN_023078 94 197 132 413 134 ptg000017l:3376738-3378882 Q2KIP6 2.53e-23 Kappa-type opioid receptor (K-OR-1) (KOR-1) Bos taurus (Bovine) adenylate cyclase-inhibiting opioid receptor signaling pathway [GO:0031635]; defense response to virus [GO:0051607]; G protein-coupled opioid receptor signaling pathway [GO:0038003]; immune response [GO:0006955]; locomotory behavior [GO:0007626]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of saliva secretion [GO:0046877]; sensory perception of pain [GO:0019233] GO:0004930; GO:0004985; GO:0005654; GO:0005829; GO:0005886; GO:0006955; GO:0007200; GO:0007218; GO:0007626; GO:0016020; GO:0019233; GO:0031635; GO:0038003; GO:0038048; GO:0042277; GO:0042923; GO:0043005; GO:0046877; GO:0051607 34725 FUN_023079 1924 1139 967 1510 1489 NA NA NA NA NA NA NA 34726 FUN_008819 0 3 0 0 15 NA NA NA NA NA NA NA 34727 FUN_008811 0 0 0 0 67 NA NA NA NA NA NA NA 34728 FUN_008810 36 0 0 0 0 NA NA NA NA NA NA NA 34729 FUN_008817 0 13 0 0 0 NA NA NA NA NA NA NA 34730 FUN_008816 62 29 0 0 23 NA NA NA NA NA NA NA 34731 FUN_008814 57 33 0 0 17 NA NA NA NA NA NA NA 34732 FUN_028574 64 13 35 1 49 NA NA NA NA NA NA NA 34733 FUN_028578 0 0 0 21 0 NA NA NA NA NA NA NA 34734 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.13e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34735 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.13e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34736 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.13e-59 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34737 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.74e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34738 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.74e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34739 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.74e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34740 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.32e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34741 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.32e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34742 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.32e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34743 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.53e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34744 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.53e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34745 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.25e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34746 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.25e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34747 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.25e-42 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34748 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 3.94e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34749 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 3.94e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34750 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.95e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34751 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.95e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34752 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.95e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34753 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 3.68e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34754 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 3.68e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34755 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.38e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34756 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.38e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34757 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.82e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34758 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.82e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34759 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.91e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34760 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.91e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34761 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 5.45e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34762 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 5.45e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34763 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.15e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34764 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 8.15e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34765 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.27e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34766 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 1.27e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34767 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 2.28e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34768 FUN_028579 0 0 7 5 77 ptg000022l:1020280-1022554 Q96AY4 2.28e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 34769 FUN_022035 63 59 0 35 0 NA NA NA NA NA NA NA 34770 FUN_022034 38 4 21 0 37 NA NA NA NA NA NA NA 34771 FUN_022037 453 39 65 235 74 ptg000016l:4893394-4908431 Q9AHE8 2.52e-27 NA NA NA NA 34772 FUN_022036 286 8 61 693 250 ptg000016l:4765376-4893092 Q9AHE8 3.92e-27 NA NA NA NA 34773 FUN_022036 286 8 61 693 250 ptg000016l:4765376-4893092 Q9AHE8 1.14e-22 NA NA NA NA 34774 FUN_022031 1478 1182 693 2212 1978 NA NA NA NA NA NA NA 34775 FUN_022030 7984 3392 4002 6009 11876 ptg000016l:4651970-4679863 Q29466 1.17e-49 V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) Bos taurus (Bovine) pH reduction [GO:0045851]; proton transmembrane transport [GO:1902600]; vacuolar acidification [GO:0007035] GO:0000220; GO:0005886; GO:0007035; GO:0016471; GO:0030665; GO:0030672; GO:0042470; GO:0045851; GO:0046961; GO:0051117; GO:1902600 34776 FUN_022030 7984 3392 4002 6009 11876 ptg000016l:4651970-4679863 Q29466 1.17e-49 V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) Bos taurus (Bovine) pH reduction [GO:0045851]; proton transmembrane transport [GO:1902600]; vacuolar acidification [GO:0007035] GO:0000220; GO:0005886; GO:0007035; GO:0016471; GO:0030665; GO:0030672; GO:0042470; GO:0045851; GO:0046961; GO:0051117; GO:1902600 34777 FUN_022030 7984 3392 4002 6009 11876 ptg000016l:4651970-4679863 Q29466 9.97e-27 V-type proton ATPase 116 kDa subunit a 1 (V-ATPase 116 kDa subunit a 1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) Bos taurus (Bovine) pH reduction [GO:0045851]; proton transmembrane transport [GO:1902600]; vacuolar acidification [GO:0007035] GO:0000220; GO:0005886; GO:0007035; GO:0016471; GO:0030665; GO:0030672; GO:0042470; GO:0045851; GO:0046961; GO:0051117; GO:1902600 34778 FUN_022033 0 0 0 0 15 NA NA NA NA NA NA NA 34779 FUN_022039 2580 1971 1590 1820 1647 NA NA NA NA NA NA NA 34780 FUN_022038 724 450 175 198 0 NA NA NA NA NA NA NA 34781 FUN_030174 44 2 19 0 9 NA NA NA NA NA NA NA 34782 FUN_041609 275 135 121 209 302 NA NA NA NA NA NA NA 34783 FUN_041608 848 460 417 1130 911 NA NA NA NA NA NA NA 34784 FUN_041601 17 11 0 61 63 NA NA NA NA NA NA NA 34785 FUN_041600 83 377 116 200 127 NA NA NA NA NA NA NA 34786 FUN_041603 120 94 113 178 194 ptg000035l:5822287-5823382 Q924H0 3.6e-35 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide NPFF receptor) Mus musculus (Mouse) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 34787 FUN_041605 0 0 0 6 0 NA NA NA NA NA NA NA 34788 FUN_041604 42 40 29 91 47 NA NA NA NA NA NA NA 34789 FUN_041607 8510 6564 4288 10446 8906 NA NA NA NA NA NA NA 34790 FUN_041606 20 11 9 22 0 ptg000035l:5871848-5874358 Q9EQD2 6.44e-44 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 34791 FUN_014144 43 0 18 7 0 NA NA NA NA NA NA NA 34792 FUN_014145 0 0 5 9 0 NA NA NA NA NA NA NA 34793 FUN_014140 0 7 10 14 31 NA NA NA NA NA NA NA 34794 FUN_014141 37 0 33 10 37 NA NA NA NA NA NA NA 34795 FUN_014142 0 0 4 4 6 NA NA NA NA NA NA NA 34796 FUN_023398 2169 4303 3839 3445 3574 NA NA NA NA NA NA NA 34797 FUN_025023 51 29 0 0 0 NA NA NA NA NA NA NA 34798 FUN_025022 10 0 0 0 0 NA NA NA NA NA NA NA 34799 FUN_025026 50 28 0 0 0 NA NA NA NA NA NA NA 34800 FUN_013642 124 145 0 201 94 ptg000008l:24889716-24892510 Q9EQK7 6.88e-48 Protein-S-isoprenylcysteine O-methyltransferase (EC 2.1.1.100) (Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT) Mus musculus (Mouse) bone mineralization [GO:0030282]; C-terminal protein methylation [GO:0006481]; determination of adult lifespan [GO:0008340]; fibroblast proliferation [GO:0048144]; in utero embryonic development [GO:0001701]; liver development [GO:0001889]; multicellular organism growth [GO:0035264]; neuromuscular process [GO:0050905]; positive regulation of fibroblast proliferation [GO:0048146]; protein localization [GO:0008104]; protein methylation [GO:0006479]; regulation of cellular senescence [GO:2000772]; regulation of protein localization [GO:0032880]; regulation of Ras protein signal transduction [GO:0046578]; S-adenosylhomocysteine metabolic process [GO:0046498]; S-adenosylmethioninamine metabolic process [GO:0046499]; TOR signaling [GO:0031929] GO:0001701; GO:0001889; GO:0004671; GO:0005783; GO:0005789; GO:0006479; GO:0006481; GO:0008104; GO:0008140; GO:0008340; GO:0016020; GO:0030282; GO:0031929; GO:0032880; GO:0035264; GO:0046498; GO:0046499; GO:0046578; GO:0048144; GO:0048146; GO:0050905; GO:2000772 34801 FUN_014611 1720 1622 828 1292 1226 NA NA NA NA NA NA NA 34802 FUN_023391 11 0 3 0 8 NA NA NA NA NA NA NA 34803 FUN_023390 36 86 97 111 33 ptg000017l:7004770-7005499 Q04892 7.11e-35 Transcription factor SOX-14 Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; entrainment of circadian clock [GO:0009649]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of DNA-templated transcription [GO:0006355]; regulation of neuron migration [GO:2001222]; visual perception [GO:0007601] GO:0000122; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0005667; GO:0006355; GO:0007601; GO:0009649; GO:0009653; GO:0030154; GO:0043565; GO:0045892; GO:1990837; GO:2001222 34804 FUN_023397 441 1388 1240 1565 1539 NA NA NA NA NA NA NA 34805 FUN_013647 98 44 117 35 135 NA NA NA NA NA NA NA 34806 FUN_013644 4733 16559 10862 7898 8392 ptg000008l:24938190-24939705 P12394 1.08e-132 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; progesterone metabolic process [GO:0042448]; steroid biosynthetic process [GO:0006694]; steroid metabolic process [GO:0008202] GO:0004508; GO:0005506; GO:0006694; GO:0008202; GO:0016020; GO:0020037; GO:0042446; GO:0042448; GO:0047442 34807 FUN_023394 2223 2077 1870 1791 2292 NA NA NA NA NA NA NA 34808 FUN_024082 287 168 128 228 188 NA NA NA NA NA NA NA 34809 FUN_024080 76 96 92 78 197 NA NA NA NA NA NA NA 34810 FUN_024081 34 6 86 3 187 NA NA NA NA NA NA NA 34811 FUN_024086 221 401 44 352 95 NA NA NA NA NA NA NA 34812 FUN_024087 6017 8894 4732 7333 3105 NA NA NA NA NA NA NA 34813 FUN_024085 0 23 0 10 0 NA NA NA NA NA NA NA 34814 FUN_026718 3770 3235 2702 2999 2285 NA NA NA NA NA NA NA 34815 FUN_031738 9281 7961 3505 6491 4704 ptg000023l:24874516-24882307 Q80ZJ7 5.32e-25 Sorting nexin-32 (Sorting nexin-6B) Mus musculus (Mouse) protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005829; GO:0015031; GO:0035091; GO:0042147 34816 FUN_031739 5240 6730 2294 6539 4733 NA NA NA NA NA NA NA 34817 FUN_031734 423 916 385 385 391 ptg000023l:24858437-24863761 Q9ER41 4.95e-69 Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B) Mus musculus (Mouse) chaperone cofactor-dependent protein refolding [GO:0051085]; endoplasmic reticulum organization [GO:0007029]; nuclear membrane organization [GO:0071763]; protein localization to nucleus [GO:0034504] GO:0005524; GO:0005635; GO:0005737; GO:0005783; GO:0005788; GO:0007029; GO:0016887; GO:0019894; GO:0031965; GO:0034504; GO:0042802; GO:0051085; GO:0071763 34818 FUN_031732 1165 1387 873 1200 1068 NA NA NA NA NA NA NA 34819 FUN_031733 1755 1290 623 969 766 NA NA NA NA NA NA NA 34820 FUN_031730 26 0 17 19 49 ptg000023l:24842243-24843209 O15819 1.75e-47 Histone H3.3 type a (Histone 3, variant 3 type a) Dictyostelium discoideum (Social amoeba) chromatin remodeling [GO:0006338]; epigenetic regulation of gene expression [GO:0040029]; response to mercury ion [GO:0046689] GO:0000786; GO:0003677; GO:0005634; GO:0006338; GO:0030527; GO:0030874; GO:0040029; GO:0046689; GO:0046982 34821 FUN_031731 1513 1053 586 818 843 NA NA NA NA NA NA NA 34822 FUN_039508 0 0 0 0 22 NA NA NA NA NA NA NA 34823 FUN_019262 0 9 0 3 0 NA NA NA NA NA NA NA 34824 FUN_039505 0 0 110 0 0 NA NA NA NA NA NA NA 34825 FUN_039504 18 21 16 47 32 NA NA NA NA NA NA NA 34826 FUN_039503 4 0 19 0 63 NA NA NA NA NA NA NA 34827 FUN_031080 2336 2185 1225 1650 1423 NA NA NA NA NA NA NA 34828 FUN_031081 1664 2111 669 658 331 NA NA NA NA NA NA NA 34829 FUN_031083 711 531 259 424 954 ptg000023l:17093702-17129755 P14381 2.09e-91 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 34830 FUN_031084 0 0 32 0 175 NA NA NA NA NA NA NA 34831 FUN_031085 2419 2084 1272 2563 1734 NA NA NA NA NA NA NA 34832 FUN_031086 0 25 0 0 27 ptg000023l:17196196-17201216 P70191 1e-28 TNF receptor-associated factor 5 Mus musculus (Mouse) apoptotic process [GO:0006915]; interleukin-17-mediated signaling pathway [GO:0097400]; mRNA stabilization [GO:0048255]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of JNK cascade [GO:0046330]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein K63-linked ubiquitination [GO:0070534]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0005164; GO:0005813; GO:0005829; GO:0006915; GO:0007165; GO:0008270; GO:0008284; GO:0009898; GO:0023019; GO:0031625; GO:0031996; GO:0033209; GO:0035631; GO:0042802; GO:0042981; GO:0043122; GO:0043123; GO:0046330; GO:0048255; GO:0051091; GO:0051092; GO:0070534; GO:0097400 34833 FUN_031087 31 14 29 24 150 NA NA NA NA NA NA NA 34834 FUN_031088 0 32 0 39 72 ptg000023l:17220061-17228076 B8VIU6 7.88e-32 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 34835 FUN_008354 42 0 8 0 18 NA NA NA NA NA NA NA 34836 FUN_008355 37 0 8 41 34 NA NA NA NA NA NA NA 34837 FUN_000169 2 0 4 0 15 ntLink_4:280488-281251 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 34838 FUN_043943 4 3 7 3 35 NA NA NA NA NA NA NA 34839 FUN_026909 309 266 223 281 394 ptg000020l:14816963-14819720 Q75T13 3.81e-111 GPI inositol-deacylase (EC 3.1.-.-) (Post-GPI attachment to proteins factor 1) (hPGAP1) Homo sapiens (Human) anterior/posterior axis specification [GO:0009948]; attachment of GPI anchor to protein [GO:0016255]; embryonic pattern specification [GO:0009880]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; forebrain regionalization [GO:0021871]; GPI anchor metabolic process [GO:0006505]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; protein transport [GO:0015031]; sensory perception of sound [GO:0007605] GO:0005783; GO:0005789; GO:0006505; GO:0006888; GO:0007605; GO:0009880; GO:0009948; GO:0015031; GO:0016255; GO:0016788; GO:0021871; GO:0050185; GO:1902953 34840 FUN_026908 0 36 22 44 11 NA NA NA NA NA NA NA 34841 FUN_026905 56 33 37 1301 237 NA NA NA NA NA NA NA 34842 FUN_008350 0 3 0 0 33 NA NA NA NA NA NA NA 34843 FUN_026907 31 4 10 7 95 NA NA NA NA NA NA NA 34844 FUN_026906 0 14 0 0 29 NA NA NA NA NA NA NA 34845 FUN_026901 1037 476 568 1007 639 NA NA NA NA NA NA NA 34846 FUN_026903 198 153 27 85 12 ptg000020l:14793810-14796996 Q9Y239 1.12e-25 Nucleotide-binding oligomerization domain-containing protein 1 (Caspase recruitment domain-containing protein 4) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; apoptotic process [GO:0006915]; cellular response to muramyl dipeptide [GO:0071225]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; ERK1 and ERK2 cascade [GO:0070371]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; pattern recognition receptor signaling pathway [GO:0002221]; positive regulation of cell death [GO:0010942]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase activity [GO:0051000]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of xenophagy [GO:1904417]; regulation of apoptotic process [GO:0042981]; signal transduction [GO:0007165]; xenophagy [GO:0098792] GO:0002221; GO:0002606; GO:0005524; GO:0005737; GO:0005829; GO:0005886; GO:0006915; GO:0006919; GO:0006952; GO:0006954; GO:0007165; GO:0007249; GO:0007254; GO:0008656; GO:0009595; GO:0010942; GO:0016045; GO:0016323; GO:0016324; GO:0032731; GO:0032755; GO:0032757; GO:0032760; GO:0035556; GO:0038187; GO:0042742; GO:0042802; GO:0042803; GO:0042834; GO:0042981; GO:0043123; GO:0043280; GO:0044877; GO:0045087; GO:0045335; GO:0046330; GO:0050700; GO:0050830; GO:0051000; GO:0051092; GO:0060907; GO:0070371; GO:0070374; GO:0071225; GO:0098792; GO:1901224; GO:1904417 34847 FUN_008351 63 56 38 114 114 ptg000002l:10681123-10684059 B3EX02 4.75e-31 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34848 FUN_044022 14 0 2 6 90 NA NA NA NA NA NA NA 34849 FUN_008358 188 44 0 106 53 ptg000002l:10718839-10721539 B3EX02 3.97e-30 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34850 FUN_008359 108 81 25 162 94 ptg000002l:10731493-10732967 B3EX02 1.68e-31 MAM and fibronectin type III domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576; GO:0016020 34851 FUN_019554 498 174 60 98 0 NA NA NA NA NA NA NA 34852 FUN_014307 15 0 7 0 0 NA NA NA NA NA NA NA 34853 FUN_014304 0 0 0 0 7 NA NA NA NA NA NA NA 34854 FUN_014305 341 88 13 65 407 NA NA NA NA NA NA NA 34855 FUN_037367 679 461 0 712 1997 NA NA NA NA NA NA NA 34856 FUN_037366 0 0 2 6 27 NA NA NA NA NA NA NA 34857 FUN_037365 11 11 723 1251 567 NA NA NA NA NA NA NA 34858 FUN_037364 275 226 467 303 431 NA NA NA NA NA NA NA 34859 FUN_037363 313 194 274 699 304 NA NA NA NA NA NA NA 34860 FUN_037362 385 68 125 60 142 NA NA NA NA NA NA NA 34861 FUN_037361 325 180 0 138 721 NA NA NA NA NA NA NA 34862 FUN_037360 248 128 0 146 490 NA NA NA NA NA NA NA 34863 FUN_014610 13388 11357 6183 8843 5568 ptg000009l:1502519-1508880 Q10949 1.92e-25 Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain] Caenorhabditis elegans lipid droplet formation [GO:0140042]; phosphatidylethanolamine biosynthetic process [GO:0006646]; protein autoprocessing [GO:0016540] GO:0004609; GO:0005739; GO:0005743; GO:0005811; GO:0006646; GO:0016540; GO:0140042 34864 FUN_014610 13388 11357 6183 8843 5568 ptg000009l:1502519-1508880 Q10949 1.92e-25 Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain] Caenorhabditis elegans lipid droplet formation [GO:0140042]; phosphatidylethanolamine biosynthetic process [GO:0006646]; protein autoprocessing [GO:0016540] GO:0004609; GO:0005739; GO:0005743; GO:0005811; GO:0006646; GO:0016540; GO:0140042 34865 FUN_044028 0 0 2 17 38 NA NA NA NA NA NA NA 34866 FUN_037369 6607 2748 3972 8548 6822 NA NA NA NA NA NA NA 34867 FUN_005445 0 0 6 24 18 NA NA NA NA NA NA NA 34868 FUN_005444 0 4 75 0 25 NA NA NA NA NA NA NA 34869 FUN_005443 0 0 22 0 0 NA NA NA NA NA NA NA 34870 FUN_041355 0 0 0 20 11 NA NA NA NA NA NA NA 34871 FUN_005449 4 23 85 64 15 NA NA NA NA NA NA NA 34872 FUN_001537 7 7 13 60 89 NA NA NA NA NA NA NA 34873 FUN_001536 205 69 54 76 57 NA NA NA NA NA NA NA 34874 FUN_001535 1339 585 574 847 752 NA NA NA NA NA NA NA 34875 FUN_001534 639 347 369 502 491 NA NA NA NA NA NA NA 34876 FUN_001533 100 86 45 67 0 ntLink_6:13395326-13397408 Q5R634 7.41e-37 Divergent protein kinase domain 1A (Protein FAM69A) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) NA GO:0005789 34877 FUN_001532 4999 4323 2995 4527 4493 NA NA NA NA NA NA NA 34878 FUN_001531 3902 2538 2215 3540 3298 ntLink_6:13329954-13369257 G3V7Q0 2.44e-54 DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) Rattus norvegicus (Rat) negative regulation of neuron projection development [GO:0010977]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0005085; GO:0005794; GO:0005802; GO:0005829; GO:0010977; GO:0030904; GO:0031267; GO:0042147 34879 FUN_001531 3902 2538 2215 3540 3298 ntLink_6:13329954-13369257 G3V7Q0 7.17e-31 DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) Rattus norvegicus (Rat) negative regulation of neuron projection development [GO:0010977]; retrograde transport, endosome to Golgi [GO:0042147] GO:0000139; GO:0005085; GO:0005794; GO:0005802; GO:0005829; GO:0010977; GO:0030904; GO:0031267; GO:0042147 34880 FUN_001530 6052 4494 3122 6015 5224 NA NA NA NA NA NA NA 34881 FUN_001539 7 12 7 65 99 NA NA NA NA NA NA NA 34882 FUN_041351 0 7 0 0 0 NA NA NA NA NA NA NA 34883 FUN_026711 928 310 149 215 130 NA NA NA NA NA NA NA 34884 FUN_026013 10536 3919 4244 18301 13979 NA NA NA NA NA NA NA 34885 FUN_026012 6690 2041 1754 8882 6129 NA NA NA NA NA NA NA 34886 FUN_026011 5298 2044 2697 6885 5483 NA NA NA NA NA NA NA 34887 FUN_026010 1443 266 372 1360 1702 NA NA NA NA NA NA NA 34888 FUN_026017 9 0 40 0 7 NA NA NA NA NA NA NA 34889 FUN_026016 1798 728 1090 2622 2248 NA NA NA NA NA NA NA 34890 FUN_026015 71 118 241 200 216 ptg000020l:3450759-3453218 B0G143 1.35e-71 Mitochondrial substrate carrier family protein ucpB (Solute carrier family 25 member 30 homolog) (Uncoupler protein B) Dictyostelium discoideum (Social amoeba) mitochondrial transport [GO:0006839] GO:0005743; GO:0006839; GO:0022857 34891 FUN_026014 3680 2766 1849 2588 1804 NA NA NA NA NA NA NA 34892 FUN_026019 167 96 80 529 173 NA NA NA NA NA NA NA 34893 FUN_026018 257 161 110 665 251 NA NA NA NA NA NA NA 34894 FUN_041359 0 0 0 11 0 NA NA NA NA NA NA NA 34895 FUN_004314 25 93 8 69 41 NA NA NA NA NA NA NA 34896 FUN_004315 11 7 14 2 6 NA NA NA NA NA NA NA 34897 FUN_004316 1952 1854 1346 1708 1784 NA NA NA NA NA NA NA 34898 FUN_004317 1856 1963 1611 1646 1124 NA NA NA NA NA NA NA 34899 FUN_004310 1013 786 751 706 874 NA NA NA NA NA NA NA 34900 FUN_004311 2970 3396 1556 1730 1848 NA NA NA NA NA NA NA 34901 FUN_004312 193 65 72 148 222 ntLink_8:21793077-21809307 Q98864 5.37e-30 Protein patched homolog 1 (PTC1) (Patched 1) Danio rerio (Zebrafish) (Brachydanio rerio) camera-type eye development [GO:0043010]; cardioblast differentiation [GO:0010002]; negative regulation of muscle organ development [GO:0048635]; negative regulation of smoothened signaling pathway [GO:0045879]; osteoblast differentiation [GO:0001649]; proximal/distal pattern formation [GO:0009954]; retinal ganglion cell axon guidance [GO:0031290]; smoothened signaling pathway [GO:0007224] GO:0001649; GO:0005119; GO:0005886; GO:0007224; GO:0008158; GO:0009954; GO:0010002; GO:0031290; GO:0043010; GO:0045879; GO:0048635; GO:0097108 34902 FUN_004313 753 298 419 628 540 NA NA NA NA NA NA NA 34903 FUN_004318 120 166 171 261 190 NA NA NA NA NA NA NA 34904 FUN_004319 7 0 0 7 7 NA NA NA NA NA NA NA 34905 FUN_018123 635 161 408 1050 1190 ptg000012l:4643847-4648919 Q8VEB4 8.9e-33 Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) Mus musculus (Mouse) ceramide metabolic process [GO:0006672]; diacylglycerol biosynthetic process [GO:0006651]; fatty acid metabolic process [GO:0006631]; glycerophospholipid metabolic process [GO:0006650]; lipid metabolic process [GO:0006629]; phosphatidylcholine catabolic process [GO:0034638]; phosphatidylcholine metabolic process [GO:0046470]; phosphatidylethanolamine catabolic process [GO:0046338]; phosphatidylglycerol metabolic process [GO:0046471]; phosphatidylserine metabolic process [GO:0006658] GO:0005615; GO:0005654; GO:0005739; GO:0005764; GO:0006629; GO:0006631; GO:0006650; GO:0006651; GO:0006658; GO:0006672; GO:0008270; GO:0008374; GO:0008970; GO:0016020; GO:0016411; GO:0034638; GO:0043231; GO:0046338; GO:0046470; GO:0046471; GO:0047499; GO:0052739; GO:0052740; GO:0102545 34906 FUN_018120 21 0 20 0 31 NA NA NA NA NA NA NA 34907 FUN_018126 1839 1293 960 536 1152 NA NA NA NA NA NA NA 34908 FUN_018127 70 6 0 51 9 NA NA NA NA NA NA NA 34909 FUN_018124 255 259 136 140 322 ptg000012l:4652576-4654697 Q7ZX53 6.59e-55 Solute carrier family 22 member 15-like Xenopus laevis (African clawed frog) ion transport [GO:0006811] GO:0006811; GO:0016020; GO:0022857 34910 FUN_018125 79 7 15 0 77 NA NA NA NA NA NA NA 34911 FUN_018128 32 41 18 4 42 NA NA NA NA NA NA NA 34912 FUN_018129 1651 0 157 0 177 NA NA NA NA NA NA NA 34913 FUN_025946 101 36 94 125 48 ptg000020l:2294397-2300108 B8VIU6 2.3e-23 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 34914 FUN_025947 74 39 83 90 0 ptg000020l:2304024-2315074 B8VIU6 6.17e-25 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 34915 FUN_009511 898 201 123 2765 823 ptg000004l:7845629-7877731 A0LNR4 1.48e-42 Putative hydro-lyase Sfum_3393 (EC 4.2.1.-) Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) NA GO:0016829 34916 FUN_025941 0 0 0 18 16 NA NA NA NA NA NA NA 34917 FUN_030075 6 78 0 0 151 NA NA NA NA NA NA NA 34918 FUN_025942 41 54 70 87 47 ptg000020l:2252227-2259407 Q7TN88 3.55e-38 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 34919 FUN_025942 41 54 70 87 47 ptg000020l:2252227-2259407 Q7TN88 1.05e-24 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 34920 FUN_022957 300 39 140 354 532 ptg000017l:1967740-1968586 P32028 1.61e-26 Fork head domain-containing protein FD4 Drosophila melanogaster (Fruit fly) anatomical structure morphogenesis [GO:0009653]; cell differentiation [GO:0030154]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0009653; GO:0030154 34921 FUN_025943 1034 768 440 675 455 ptg000020l:2260338-2268878 A8WG43 6.26e-24 Coiled-coil domain-containing protein 89 (Bc8 orange-interacting protein) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005634; GO:0005737 34922 FUN_034047 574 622 418 425 389 ptg000024l:4153562-4154357 Q1LV46 1.57e-54 Protein ABHD14A (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 14A) (Abhydrolase domain-containing protein 14A) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005737; GO:0016020; GO:0016787 34923 FUN_034046 196 30 129 94 89 NA NA NA NA NA NA NA 34924 FUN_034045 951 1022 644 1330 1459 NA NA NA NA NA NA NA 34925 FUN_034044 805 1121 529 1325 2392 NA NA NA NA NA NA NA 34926 FUN_034043 181 420 212 611 322 NA NA NA NA NA NA NA 34927 FUN_034042 704 448 504 1296 966 NA NA NA NA NA NA NA 34928 FUN_034041 6 4 0 0 0 NA NA NA NA NA NA NA 34929 FUN_034040 576 392 398 500 546 NA NA NA NA NA NA NA 34930 FUN_013083 2046 1597 1027 2339 1718 NA NA NA NA NA NA NA 34931 FUN_022951 396 275 114 223 226 NA NA NA NA NA NA NA 34932 FUN_034049 2435 2105 1553 1683 1598 ptg000024l:4157724-4160893 Q9JIH2 2.07e-28 Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50) Mus musculus (Mouse) mRNA transport [GO:0051028]; neural tube formation [GO:0001841]; nucleocytoplasmic transport [GO:0006913]; protein import into nucleus [GO:0006606] GO:0001841; GO:0005635; GO:0005643; GO:0005654; GO:0006606; GO:0006913; GO:0031965; GO:0051028; GO:1990904 34933 FUN_034048 977 578 353 353 267 ptg000024l:4155085-4155862 Q6DGG1 5.99e-45 Putative protein-lysine deacylase ABHD14B (EC 2.3.1.-) (Alpha/beta hydrolase domain-containing protein 14B) (Abhydrolase domain-containing protein 14B) Rattus norvegicus (Rat) positive regulation of transcription by RNA polymerase II [GO:0045944] GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005829; GO:0016746; GO:0016787; GO:0045944 34934 FUN_027355 2 0 4 0 15 NA NA NA NA NA NA NA 34935 FUN_022959 176 83 182 0 56 NA NA NA NA NA NA NA 34936 FUN_014612 1720 1141 1022 825 1174 NA NA NA NA NA NA NA 34937 FUN_019299 62 0 49 17 170 NA NA NA NA NA NA NA 34938 FUN_005664 0 0 5 0 13 NA NA NA NA NA NA NA 34939 FUN_005663 2 0 2 0 8 NA NA NA NA NA NA NA 34940 FUN_005662 0 0 6 0 14 NA NA NA NA NA NA NA 34941 FUN_007159 1256 734 865 1092 1149 NA NA NA NA NA NA NA 34942 FUN_007158 302 241 296 422 387 NA NA NA NA NA NA NA 34943 FUN_007157 2455 2023 1064 1664 1511 NA NA NA NA NA NA NA 34944 FUN_007156 26 24 0 16 110 NA NA NA NA NA NA NA 34945 FUN_007155 2857 2058 1171 3120 2174 ptg000001l:21077775-21084893 Q9R1T9 1.56e-25 Potassium voltage-gated channel subfamily H member 4 (Brain-specific eag-like channel 2) (BEC2) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (rElk1) (Voltage-gated potassium channel subunit Kv12.3) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005886; GO:0034765; GO:0042391; GO:0071805 34946 FUN_007155 2857 2058 1171 3120 2174 ptg000001l:21077775-21084893 Q9R1T9 1.56e-25 Potassium voltage-gated channel subfamily H member 4 (Brain-specific eag-like channel 2) (BEC2) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (rElk1) (Voltage-gated potassium channel subunit Kv12.3) Rattus norvegicus (Rat) potassium ion transmembrane transport [GO:0071805]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane potential [GO:0042391] GO:0005249; GO:0005886; GO:0034765; GO:0042391; GO:0071805 34947 FUN_007154 1672 1074 862 1332 1147 NA NA NA NA NA NA NA 34948 FUN_007153 1348 858 516 1437 1188 NA NA NA NA NA NA NA 34949 FUN_007152 182 173 125 103 59 NA NA NA NA NA NA NA 34950 FUN_007151 6170 6671 3492 5949 2815 ptg000001l:21036659-21040787 Q9H4K1 7.18e-22 RIB43A-like with coiled-coils protein 2 Homo sapiens (Human) NA GO:0005634; GO:0005879 34951 FUN_007150 5197 4984 3198 3622 2039 NA NA NA NA NA NA NA 34952 FUN_005942 80 198 105 176 44 NA NA NA NA NA NA NA 34953 FUN_005943 0 0 0 0 29 NA NA NA NA NA NA NA 34954 FUN_005940 0 0 0 6 14 NA NA NA NA NA NA NA 34955 FUN_005941 469 571 283 70 49 NA NA NA NA NA NA NA 34956 FUN_005947 24 28 11 14 16 NA NA NA NA NA NA NA 34957 FUN_005944 8 110 0 28 34 NA NA NA NA NA NA NA 34958 FUN_005945 0 38 9 15 0 NA NA NA NA NA NA NA 34959 FUN_005949 3412 2893 833 845 4098 NA NA NA NA NA NA NA 34960 FUN_019740 0 0 0 0 6 NA NA NA NA NA NA NA 34961 FUN_034955 3841 1489 1639 4192 2416 ptg000025l:2063592-2082446 Q54NW6 2.18e-27 5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase) Dictyostelium discoideum (Social amoeba) glutathione metabolic process [GO:0006749] GO:0005524; GO:0006749; GO:0017168 34962 FUN_034954 2514 1335 1126 849 1425 ptg000025l:2059877-2061904 Q3UHD2 1.79e-95 Glucose-fructose oxidoreductase domain-containing protein 1 (EC 1.-.-.-) Mus musculus (Mouse) NA GO:0000166; GO:0005576; GO:0016491 34963 FUN_034957 2086 981 804 1130 1356 ptg000025l:2100756-2103801 Q1NZ26 1.53e-22 Uncharacterized protein F13E9.13, mitochondrial Caenorhabditis elegans NA GO:0005739 34964 FUN_034956 2133 1527 1207 2264 1113 NA NA NA NA NA NA NA 34965 FUN_034951 488 149 249 517 506 NA NA NA NA NA NA NA 34966 FUN_030669 185 79 102 433 163 NA NA NA NA NA NA NA 34967 FUN_034953 891 1145 493 618 331 NA NA NA NA NA NA NA 34968 FUN_034952 505 385 159 420 444 NA NA NA NA NA NA NA 34969 FUN_034959 158 60 227 293 333 NA NA NA NA NA NA NA 34970 FUN_034958 3640 973 431 1905 1368 NA NA NA NA NA NA NA 34971 FUN_023510 16 0 0 3 23 NA NA NA NA NA NA NA 34972 FUN_014613 2508 1570 1380 3058 2751 ptg000009l:1518045-1567110 Q92616 2.13e-48 eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; regulation of translation [GO:0006417] GO:0003723; GO:0005737; GO:0005829; GO:0005840; GO:0005844; GO:0006417; GO:0008135; GO:0008494; GO:0016020; GO:0019887; GO:0034198; GO:0045296; GO:1990253 34973 FUN_014613 2508 1570 1380 3058 2751 ptg000009l:1518045-1567110 Q92616 2.13e-48 eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; regulation of translation [GO:0006417] GO:0003723; GO:0005737; GO:0005829; GO:0005840; GO:0005844; GO:0006417; GO:0008135; GO:0008494; GO:0016020; GO:0019887; GO:0034198; GO:0045296; GO:1990253 34974 FUN_014613 2508 1570 1380 3058 2751 ptg000009l:1518045-1567110 Q92616 4.16e-34 eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; regulation of translation [GO:0006417] GO:0003723; GO:0005737; GO:0005829; GO:0005840; GO:0005844; GO:0006417; GO:0008135; GO:0008494; GO:0016020; GO:0019887; GO:0034198; GO:0045296; GO:1990253 34975 FUN_014613 2508 1570 1380 3058 2751 ptg000009l:1518045-1567110 Q92616 2.22e-28 eIF-2-alpha kinase activator GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1) Homo sapiens (Human) cellular response to amino acid starvation [GO:0034198]; cellular response to leucine starvation [GO:1990253]; regulation of translation [GO:0006417] GO:0003723; GO:0005737; GO:0005829; GO:0005840; GO:0005844; GO:0006417; GO:0008135; GO:0008494; GO:0016020; GO:0019887; GO:0034198; GO:0045296; GO:1990253 34976 FUN_022448 1761 1423 694 1853 1521 NA NA NA NA NA NA NA 34977 FUN_015568 0 13 0 25 15 NA NA NA NA NA NA NA 34978 FUN_023513 66 40 38 43 0 ptg000017l:8463626-8464685 P35406 5.33e-40 D(1) dopamine receptor (Dopamine D1 receptor) Carassius auratus (Goldfish) regulation of biological quality [GO:0065008] GO:0004930; GO:0005886; GO:0065008 34979 FUN_006208 0 29 1 3 0 NA NA NA NA NA NA NA 34980 FUN_042008 2674 2084 924 3004 1994 NA NA NA NA NA NA NA 34981 FUN_042009 393 221 220 835 475 NA NA NA NA NA NA NA 34982 FUN_042007 182 93 52 119 85 NA NA NA NA NA NA NA 34983 FUN_006207 12811 17033 8981 20350 8224 NA NA NA NA NA NA NA 34984 FUN_042002 4741 4269 2950 3503 1803 NA NA NA NA NA NA NA 34985 FUN_006201 0 40 0 0 0 ptg000001l:9156747-9157781 E9Q236 4.19e-25 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Mus musculus (Mouse) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; fatty acid derivative transport [GO:1901571]; leukotriene transport [GO:0071716]; organic hydroxy compound transport [GO:0015850]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; urate transport [GO:0015747]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015665; GO:0015721; GO:0015732; GO:0015747; GO:0015850; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:1901571 34986 FUN_042000 397 219 215 292 278 NA NA NA NA NA NA NA 34987 FUN_042001 1597 1217 918 1183 1209 NA NA NA NA NA NA NA 34988 FUN_020596 0 0 0 55 8 NA NA NA NA NA NA NA 34989 FUN_022442 49 136 106 158 203 NA NA NA NA NA NA NA 34990 FUN_040531 2 0 12 4 0 NA NA NA NA NA NA NA 34991 FUN_040534 414 301 260 668 717 ptg000031l:9965302-10042356 O00370 1.56e-55 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 34992 FUN_040534 414 301 260 668 717 ptg000031l:9965302-10042356 O00370 1.56e-55 LINE-1 retrotransposable element ORF2 protein (ORF2p) [Includes: Reverse transcriptase (EC 2.7.7.49); Endonuclease (EC 3.1.21.-)] Homo sapiens (Human) DNA recombination [GO:0006310]; nucleic acid phosphodiester bond hydrolysis [GO:0090305]; reverse transcription involved in RNA-mediated transposition [GO:0032199]; transposition, RNA-mediated [GO:0032197] GO:0003723; GO:0003964; GO:0006310; GO:0009036; GO:0032197; GO:0032199; GO:0046872; GO:0090305 34993 FUN_040535 145 230 0 138 185 NA NA NA NA NA NA NA 34994 FUN_040536 614 122 137 180 336 ptg000031l:10072974-10110141 P08548 1.01e-35 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 34995 FUN_040537 1008 0 0 34 43 NA NA NA NA NA NA NA 34996 FUN_040539 16 16 3 9 9 NA NA NA NA NA NA NA 34997 FUN_035608 680 1166 389 447 936 NA NA NA NA NA NA NA 34998 FUN_035609 357 277 315 590 592 NA NA NA NA NA NA NA 34999 FUN_015567 426 101 92 176 249 NA NA NA NA NA NA NA 35000 FUN_034006 1879 1182 1454 1740 1317 NA NA NA NA NA NA NA 35001 FUN_035602 3757 3760 2236 2714 2083 NA NA NA NA NA NA NA 35002 FUN_035603 1699 1089 1021 1210 1044 NA NA NA NA NA NA NA 35003 FUN_035600 30467 21062 6820 15661 11279 NA NA NA NA NA NA NA 35004 FUN_035606 539 1571 967 739 1006 NA NA NA NA NA NA NA 35005 FUN_035607 159 16 61 142 95 NA NA NA NA NA NA NA 35006 FUN_035604 16 7 11 25 0 NA NA NA NA NA NA NA 35007 FUN_035605 0 0 22 0 0 NA NA NA NA NA NA NA 35008 FUN_036559 2 0 0 0 12 ptg000025l:19669744-19670980 P14381 1.03e-21 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 35009 FUN_036558 41 0 0 0 0 NA NA NA NA NA NA NA 35010 FUN_036556 260 9 188 302 4 NA NA NA NA NA NA NA 35011 FUN_036555 0 6 1 5 1 NA NA NA NA NA NA NA 35012 FUN_036552 9 0 0 29 0 NA NA NA NA NA NA NA 35013 FUN_019306 91 0 0 6 71 NA NA NA NA NA NA NA 35014 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 5.57e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35015 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 3.27e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35016 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 8.17e-58 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35017 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 6.93e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35018 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 1.93e-54 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35019 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 1.16e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35020 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 3.71e-52 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35021 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 7.3e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35022 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 1.58e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35023 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 3.15e-27 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35024 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 2.2e-26 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35025 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 1.45e-25 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35026 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 4.71e-25 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35027 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 7.14e-25 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35028 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 1.65e-24 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35029 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 2.26e-24 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35030 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 5.09e-24 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35031 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 2.11e-22 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35032 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 3.44e-22 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35033 FUN_032074 2333 1627 1165 2967 1444 ptg000023l:28635313-28650798 P10079 4.15e-22 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 35034 FUN_032075 1980 1822 1334 1652 802 ptg000023l:28654835-28655306 A7SAZ1 5.36e-49 UPF0669 protein v1g209471 Nematostella vectensis (Starlet sea anemone) NA GO:0005576 35035 FUN_032076 1094 556 375 590 523 NA NA NA NA NA NA NA 35036 FUN_032077 304 182 175 219 385 NA NA NA NA NA NA NA 35037 FUN_032070 1057 709 563 305 493 NA NA NA NA NA NA NA 35038 FUN_032071 1341 960 872 586 1179 NA NA NA NA NA NA NA 35039 FUN_032072 22 7 0 0 0 NA NA NA NA NA NA NA 35040 FUN_032073 22 19 18 19 59 NA NA NA NA NA NA NA 35041 FUN_032078 801 498 899 1054 1577 NA NA NA NA NA NA NA 35042 FUN_042806 999 956 826 782 523 ptg000047l:295035-297352 Q9JHE4 3.08e-28 Galactosylceramide sulfotransferase (GalCer sulfotransferase) (EC 2.8.2.11) (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase) (3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase) (Cerebroside sulfotransferase) Mus musculus (Mouse) galactosylceramide biosynthetic process [GO:0006682]; galactosylceramide metabolic process [GO:0006681]; glycerolipid metabolic process [GO:0046486]; glycolipid biosynthetic process [GO:0009247]; myelination [GO:0042552]; spermatogenesis [GO:0007283]; sphingolipid metabolic process [GO:0006665] GO:0000139; GO:0001733; GO:0006665; GO:0006681; GO:0006682; GO:0007283; GO:0008146; GO:0009247; GO:0016020; GO:0042552; GO:0046486; GO:0050694 35043 FUN_030078 0 20 0 0 67 NA NA NA NA NA NA NA 35044 FUN_043841 15 3 27 3 64 NA NA NA NA NA NA NA 35045 FUN_043840 1 1 3 5 10 NA NA NA NA NA NA NA 35046 FUN_043844 0 0 10 0 8 NA NA NA NA NA NA NA 35047 FUN_043847 0 0 2 0 18 NA NA NA NA NA NA NA 35048 FUN_032389 3330 2248 1375 2293 2204 NA NA NA NA NA NA NA 35049 FUN_032386 251 119 212 226 239 NA NA NA NA NA NA NA 35050 FUN_043848 16 3 28 3 72 NA NA NA NA NA NA NA 35051 FUN_032384 1280 718 667 554 383 ptg000023l:31377314-31379947 Q92113 4.34e-66 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 35052 FUN_032385 5599 2695 3262 5164 5246 NA NA NA NA NA NA NA 35053 FUN_032382 2405 1783 768 1395 1071 ptg000023l:31357197-31361081 Q92113 2.26e-63 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 35054 FUN_032383 695 193 196 262 215 ptg000023l:31362651-31375439 Q92113 6.57e-65 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 35055 FUN_032383 695 193 196 262 215 ptg000023l:31362651-31375439 Q92113 4.77e-64 Steroid 17-alpha-hydroxylase/17,20 lyase (EC 1.14.14.19) (EC 1.14.14.32) (17-alpha-hydroxyprogesterone aldolase) (CYPXVII) (Cytochrome P450 17A1) (Cytochrome P450-C17) (Cytochrome P450c17) Squalus acanthias (Spiny dogfish) steroid biosynthetic process [GO:0006694] GO:0004508; GO:0005506; GO:0006694; GO:0016020; GO:0020037; GO:0047442 35056 FUN_032380 2829 1726 1392 1770 1394 ptg000023l:31331079-31332714 O77649 3.47e-66 UDP-glucuronosyltransferase 2B20 (UDPGT 2B20) (EC 2.4.1.17) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) NA GO:0005789; GO:0015020 35057 FUN_032381 413 186 219 436 594 NA NA NA NA NA NA NA 35058 FUN_007632 0 1 0 0 7 NA NA NA NA NA NA NA 35059 FUN_007633 0 0 0 0 55 NA NA NA NA NA NA NA 35060 FUN_007631 0 0 21 0 0 NA NA NA NA NA NA NA 35061 FUN_007636 20 0 0 0 0 NA NA NA NA NA NA NA 35062 FUN_007634 35 0 20 0 38 NA NA NA NA NA NA NA 35063 FUN_042805 111 75 25 96 95 NA NA NA NA NA NA NA 35064 FUN_005168 1340 632 629 525 577 NA NA NA NA NA NA NA 35065 FUN_005169 1868 980 927 978 753 NA NA NA NA NA NA NA 35066 FUN_041728 96 82 49 183 118 NA NA NA NA NA NA NA 35067 FUN_041729 10 0 29 5 0 NA NA NA NA NA NA NA 35068 FUN_005164 42 10 35 15 66 NA NA NA NA NA NA NA 35069 FUN_041727 423 257 175 273 441 ptg000035l:6827105-6834773 A0A1L8EYB2 6.97e-57 Dynein axonemal assembly factor 8 (Dynein axonemal-associated protein 1) Xenopus laevis (African clawed frog) outer dynein arm assembly [GO:0036158] GO:0036158; GO:0070840; GO:0120293 35070 FUN_041724 1639 1106 1179 1542 1343 NA NA NA NA NA NA NA 35071 FUN_041725 1126 1181 706 1059 1339 NA NA NA NA NA NA NA 35072 FUN_041722 726 1388 1472 1515 395 NA NA NA NA NA NA NA 35073 FUN_041723 6395 5991 3209 4132 4139 ptg000035l:6800671-6808158 Q9VPH8 6.94e-37 Retinoblastoma-binding protein 5 homolog Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; histone H3-K4 methylation [GO:0051568] GO:0006325; GO:0044665; GO:0044666; GO:0048188; GO:0051568 35074 FUN_041723 6395 5991 3209 4132 4139 ptg000035l:6800671-6808158 Q9VPH8 6.94e-37 Retinoblastoma-binding protein 5 homolog Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; histone H3-K4 methylation [GO:0051568] GO:0006325; GO:0044665; GO:0044666; GO:0048188; GO:0051568 35075 FUN_005162 52 51 27 32 28 NA NA NA NA NA NA NA 35076 FUN_041721 2785 2881 2259 2019 1426 ptg000035l:6790698-6792011 Q5R4G2 4.28e-34 Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid catabolic process [GO:0016042]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283] GO:0001650; GO:0003847; GO:0005829; GO:0005886; GO:0007283; GO:0008247; GO:0016042; GO:0016239; GO:0042803; GO:0046982 35077 FUN_041721 2785 2881 2259 2019 1426 ptg000035l:6790698-6792011 Q5R4G2 4.28e-34 Platelet-activating factor acetylhydrolase IB subunit alpha2 (EC 3.1.1.47) (PAF acetylhydrolase 30 kDa subunit) (PAF-AH 30 kDa subunit) (PAF-AH subunit beta) (PAFAH subunit beta) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) lipid catabolic process [GO:0016042]; positive regulation of macroautophagy [GO:0016239]; spermatogenesis [GO:0007283] GO:0001650; GO:0003847; GO:0005829; GO:0005886; GO:0007283; GO:0008247; GO:0016042; GO:0016239; GO:0042803; GO:0046982 35078 FUN_033384 10 7 6 20 23 NA NA NA NA NA NA NA 35079 FUN_008691 0 0 0 15 0 NA NA NA NA NA NA NA 35080 FUN_008690 0 0 0 9 0 NA NA NA NA NA NA NA 35081 FUN_032928 0 21 49 0 162 NA NA NA NA NA NA NA 35082 FUN_008695 1039 679 717 1104 379 NA NA NA NA NA NA NA 35083 FUN_008694 966 952 600 1374 1174 ptg000002l:14436900-14453518 Q6NZS4 1.56e-31 RNA-splicing ligase RtcB homolog (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) Danio rerio (Zebrafish) (Brachydanio rerio) tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate [GO:0000971]; tRNA splicing, via endonucleolytic cleavage and ligation [GO:0006388] GO:0000971; GO:0003972; GO:0005525; GO:0005634; GO:0005737; GO:0006388; GO:0046872; GO:0072669 35084 FUN_008697 663 832 1278 1284 1067 NA NA NA NA NA NA NA 35085 FUN_008696 58 0 32 9 143 NA NA NA NA NA NA NA 35086 FUN_008699 555 289 152 398 466 NA NA NA NA NA NA NA 35087 FUN_008698 34 19 92 100 163 ptg000002l:14502479-14516449 Q6PDJ1 2.44e-24 VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) Mus musculus (Mouse) NA GO:0005245; GO:0005891 35088 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 1.04e-178 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35089 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 1.02e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35090 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 8.3e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35091 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 1.65e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35092 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 6.22e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35093 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 7.14e-141 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35094 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 6.4e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35095 FUN_032921 178 26 93 78 79 ptg000023l:37682574-37687374 Q96AY4 1.98e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35096 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35097 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 5.04e-174 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35098 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 1.04e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35099 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 9.08e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35100 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 1.05e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35101 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 4.26e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35102 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 1.73e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35103 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 1.2e-107 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35104 FUN_032926 322 181 58 96 70 ptg000023l:37756879-37762597 Q96AY4 2.41e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35105 FUN_032927 3 78 92 117 155 NA NA NA NA NA NA NA 35106 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.57e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35107 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.57e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35108 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 6.1e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35109 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 6.1e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35110 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 7.52e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35111 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 2.01e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35112 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 7.88e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35113 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 6.78e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35114 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.37e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35115 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 2.48e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35116 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.23e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35117 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 3.67e-93 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35118 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.72e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35119 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 4.87e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35120 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 5.87e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35121 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.52e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35122 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 2.71e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35123 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 1.52e-67 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35124 FUN_032924 255 737 76 102 458 ptg000023l:37731836-37739049 Q96AY4 3.76e-47 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35125 FUN_032925 24 6 0 0 0 NA NA NA NA NA NA NA 35126 FUN_033039 134 163 32 132 50 ptg000023l:39165730-39175433 Q5CB03 9.98e-34 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase 1) (Glucuronosyltransferase P) (GlcAT-P) (UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase) (GlcUAT-P) Canis lupus familiaris (Dog) (Canis familiaris) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; protein glycosylation [GO:0006486] GO:0000139; GO:0005576; GO:0005789; GO:0005975; GO:0006486; GO:0015018; GO:0046872; GO:0050650 35127 FUN_033038 874 1077 601 799 500 ptg000023l:39160971-39162888 Q5ZM55 2.17e-155 Protein fem-1 homolog B (FEM1b) (FEM1-beta) Gallus gallus (Chicken) apoptotic process [GO:0006915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein ubiquitination [GO:0016567]; regulation of DNA damage checkpoint [GO:2000001]; ubiquitin-dependent protein catabolic process via the C-end degron rule pathway [GO:0140627] GO:0005634; GO:0005737; GO:0006915; GO:0016567; GO:0031462; GO:0043161; GO:0140627; GO:1990756; GO:2000001 35128 FUN_033037 570 603 334 417 495 NA NA NA NA NA NA NA 35129 FUN_033036 577 296 273 282 692 NA NA NA NA NA NA NA 35130 FUN_033035 1015 513 407 608 1093 NA NA NA NA NA NA NA 35131 FUN_033034 10 10 29 30 8 ptg000023l:39122465-39125279 Q96AY4 7.16e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35132 FUN_033034 10 10 29 30 8 ptg000023l:39122465-39125279 Q96AY4 5.41e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35133 FUN_033034 10 10 29 30 8 ptg000023l:39122465-39125279 Q96AY4 2.72e-159 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35134 FUN_033034 10 10 29 30 8 ptg000023l:39122465-39125279 Q96AY4 9.22e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35135 FUN_033034 10 10 29 30 8 ptg000023l:39122465-39125279 Q96AY4 8.01e-115 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35136 FUN_033034 10 10 29 30 8 ptg000023l:39122465-39125279 Q96AY4 2.9e-100 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35137 FUN_033033 50 0 36 16 16 NA NA NA NA NA NA NA 35138 FUN_033032 27 18 12 73 84 NA NA NA NA NA NA NA 35139 FUN_033031 127 15 39 84 96 ptg000023l:39082876-39086837 Q96AY4 1.03e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35140 FUN_033031 127 15 39 84 96 ptg000023l:39082876-39086837 Q96AY4 5.84e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35141 FUN_033031 127 15 39 84 96 ptg000023l:39082876-39086837 Q96AY4 1.99e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35142 FUN_033031 127 15 39 84 96 ptg000023l:39082876-39086837 Q96AY4 6.52e-102 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35143 FUN_033030 0 0 0 0 22 NA NA NA NA NA NA NA 35144 FUN_042828 2901 3139 1946 4194 3056 NA NA NA NA NA NA NA 35145 FUN_042829 3616 5353 3303 2941 2842 NA NA NA NA NA NA NA 35146 FUN_016740 8 39 4 5 39 NA NA NA NA NA NA NA 35147 FUN_016741 378 313 268 324 193 ptg000011l:6849220-6852975 P84039 4.94e-57 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Rattus norvegicus (Rat) cell communication [GO:0007154] GO:0000210; GO:0005886; GO:0007154; GO:0008270; GO:0016020 35148 FUN_016741 378 313 268 324 193 ptg000011l:6849220-6852975 P84039 2.17e-40 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-) Rattus norvegicus (Rat) cell communication [GO:0007154] GO:0000210; GO:0005886; GO:0007154; GO:0008270; GO:0016020 35149 FUN_016743 1641 1346 823 1145 852 ptg000011l:6865303-6887134 Q8WXE9 3.09e-62 Stonin-2 (Stoned B) Homo sapiens (Human) regulation of endocytosis [GO:0030100]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192] GO:0005730; GO:0005829; GO:0008021; GO:0016020; GO:0016192; GO:0030100; GO:0030136; GO:0031410; GO:0035615; GO:0043005; GO:0048488 35150 FUN_042825 1900 1096 886 1817 1409 NA NA NA NA NA NA NA 35151 FUN_042826 558 224 275 530 619 NA NA NA NA NA NA NA 35152 FUN_003640 0 0 50 0 0 NA NA NA NA NA NA NA 35153 FUN_003644 0 0 12 10 0 NA NA NA NA NA NA NA 35154 FUN_040097 3543 1847 1399 3133 3097 NA NA NA NA NA NA NA 35155 FUN_040096 2957 2238 1400 2235 1600 NA NA NA NA NA NA NA 35156 FUN_040095 2357 930 1344 1949 1850 NA NA NA NA NA NA NA 35157 FUN_040094 94 54 14 34 37 ptg000031l:4123524-4133225 Q5ZI78 4.51e-53 Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) Gallus gallus (Chicken) positive regulation of apoptotic process [GO:0043065] GO:0005737; GO:0043027; GO:0043065 35158 FUN_040093 155 57 112 145 128 NA NA NA NA NA NA NA 35159 FUN_040092 0 20 1 26 9 NA NA NA NA NA NA NA 35160 FUN_040091 8252 6431 5302 9850 5380 ptg000031l:4080493-4105248 Q7ZYC4 6.48e-28 Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) (EC 6.2.1.15) Xenopus laevis (African clawed frog) NA GO:0004467; GO:0005524; GO:0005737; GO:0047676 35161 FUN_040091 8252 6431 5302 9850 5380 ptg000031l:4080493-4105248 Q7ZYC4 6.48e-28 Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) (EC 6.2.1.15) Xenopus laevis (African clawed frog) NA GO:0004467; GO:0005524; GO:0005737; GO:0047676 35162 FUN_040091 8252 6431 5302 9850 5380 ptg000031l:4080493-4105248 Q7ZYC4 1.26e-22 Long-chain-fatty-acid--CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Arachidonate--CoA ligase ACSBG2) (EC 6.2.1.15) Xenopus laevis (African clawed frog) NA GO:0004467; GO:0005524; GO:0005737; GO:0047676 35163 FUN_040090 2238 1633 650 4197 1935 NA NA NA NA NA NA NA 35164 FUN_012241 2544 1275 1234 2331 2140 ptg000008l:6688583-6703569 E9Q4N7 1.92e-76 AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) Mus musculus (Mouse) chromatin remodeling [GO:0006338]; dendritic cell dendrite assembly [GO:0097026]; dendritic spine development [GO:0060996]; neuron-neuron synaptic transmission [GO:0007270]; positive regulation of DNA-templated transcription [GO:0045893]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003677; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0006338; GO:0006357; GO:0007270; GO:0016514; GO:0035060; GO:0045202; GO:0045893; GO:0060996; GO:0071565; GO:0097026 35165 FUN_012240 2789 2787 1556 3290 2235 NA NA NA NA NA NA NA 35166 FUN_012243 0 0 0 0 6 NA NA NA NA NA NA NA 35167 FUN_012242 0 0 20 10 11 NA NA NA NA NA NA NA 35168 FUN_012245 801 340 411 405 731 NA NA NA NA NA NA NA 35169 FUN_012244 852 322 327 379 324 NA NA NA NA NA NA NA 35170 FUN_012247 0 9 0 34 11 NA NA NA NA NA NA NA 35171 FUN_012246 10 19 28 30 47 NA NA NA NA NA NA NA 35172 FUN_012249 0 0 0 0 6 NA NA NA NA NA NA NA 35173 FUN_012248 21 10 17 14 0 NA NA NA NA NA NA NA 35174 FUN_028316 3129 3201 1583 1834 1928 NA NA NA NA NA NA NA 35175 FUN_028317 234 344 229 367 473 NA NA NA NA NA NA NA 35176 FUN_028314 3671 1382 1383 2476 1748 NA NA NA NA NA NA NA 35177 FUN_028315 1183 520 468 865 738 NA NA NA NA NA NA NA 35178 FUN_028312 906 869 633 1512 1016 NA NA NA NA NA NA NA 35179 FUN_028310 3 0 12 0 7 NA NA NA NA NA NA NA 35180 FUN_028318 108 88 144 208 229 NA NA NA NA NA NA NA 35181 FUN_028319 42 121 78 262 154 NA NA NA NA NA NA NA 35182 FUN_019263 0 0 0 6 0 ptg000015l:242420-245214 Q5F4A1 1.06e-42 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0046872 35183 FUN_013596 2283 726 1017 1569 1467 NA NA NA NA NA NA NA 35184 FUN_013597 712 599 575 419 516 NA NA NA NA NA NA NA 35185 FUN_013594 236 194 156 190 186 ptg000008l:24335726-24337658 Q9EP71 3.49e-45 Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) (p125) Mus musculus (Mouse) cell differentiation [GO:0030154]; spermatogenesis [GO:0007283] GO:0001650; GO:0003779; GO:0005654; GO:0005739; GO:0005829; GO:0005856; GO:0005938; GO:0007283; GO:0030154; GO:0070161 35186 FUN_013595 413 78 125 299 186 NA NA NA NA NA NA NA 35187 FUN_013592 191 60 181 215 301 NA NA NA NA NA NA NA 35188 FUN_013593 290 504 189 284 292 NA NA NA NA NA NA NA 35189 FUN_013590 574 721 322 819 514 NA NA NA NA NA NA NA 35190 FUN_013591 6123 5652 3344 3102 4392 NA NA NA NA NA NA NA 35191 FUN_042808 1562 1175 1469 1138 963 ptg000047l:322291-324308 B5X1G3 1.82e-116 Golgi pH regulator (Protein gpr89) Salmo salar (Atlantic salmon) protein transport [GO:0015031]; regulation of ion transmembrane transport [GO:0034765] GO:0000139; GO:0005244; GO:0015031; GO:0034765 35192 FUN_042808 1562 1175 1469 1138 963 ptg000047l:322291-324308 B5X1G3 1.21e-85 Golgi pH regulator (Protein gpr89) Salmo salar (Atlantic salmon) protein transport [GO:0015031]; regulation of ion transmembrane transport [GO:0034765] GO:0000139; GO:0005244; GO:0015031; GO:0034765 35193 FUN_013598 49 48 0 42 46 NA NA NA NA NA NA NA 35194 FUN_013599 14 0 0 33 15 NA NA NA NA NA NA NA 35195 FUN_043012 2367 245 1234 2705 2577 ptg000047l:2959380-2970139 Q91VE0 1.05e-55 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 35196 FUN_043012 2367 245 1234 2705 2577 ptg000047l:2959380-2970139 Q91VE0 6.23e-25 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 35197 FUN_043012 2367 245 1234 2705 2577 ptg000047l:2959380-2970139 Q91VE0 3.68e-24 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 35198 FUN_043013 1896 766 427 913 509 ptg000047l:2974734-2982060 Q91VE0 1.27e-56 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 35199 FUN_043013 1896 766 427 913 509 ptg000047l:2974734-2982060 Q91VE0 4.3e-26 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 35200 FUN_043013 1896 766 427 913 509 ptg000047l:2974734-2982060 Q91VE0 1.38e-23 Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 4) (Very long-chain acyl-CoA synthetase 4) (ACSVL4) (EC 6.2.1.-) Mus musculus (Mouse) activation of GTPase activity [GO:0090630]; establishment of localization in cell [GO:0051649]; fatty acid metabolic process [GO:0006631]; fatty acid transport [GO:0015908]; glucose import in response to insulin stimulus [GO:0044381]; lipid transport across blood-brain barrier [GO:1990379]; long-chain fatty acid import into cell [GO:0044539]; long-chain fatty acid metabolic process [GO:0001676]; long-chain fatty acid transport [GO:0015909]; medium-chain fatty acid transport [GO:0001579]; negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity [GO:0062003]; negative regulation of insulin receptor signaling pathway [GO:0046627]; positive regulation of apoptotic process [GO:0043065]; response to nutrient [GO:0007584]; skin development [GO:0043588]; very long-chain fatty acid catabolic process [GO:0042760]; very long-chain fatty acid metabolic process [GO:0000038] GO:0000038; GO:0000166; GO:0001579; GO:0001676; GO:0004467; GO:0005324; GO:0005783; GO:0005789; GO:0005886; GO:0005902; GO:0006631; GO:0007584; GO:0015908; GO:0015909; GO:0031526; GO:0031957; GO:0042760; GO:0043065; GO:0043588; GO:0044381; GO:0044539; GO:0046627; GO:0047676; GO:0051649; GO:0062003; GO:0090433; GO:0090434; GO:0090630; GO:1901480; GO:1990379 35201 FUN_043010 1228 1314 437 538 691 ptg000047l:2940046-2953221 Q8CGF6 5.06e-51 WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; anterior commissure morphogenesis [GO:0021960]; autophagy [GO:0006914]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; cerebral cortex radial glia-guided migration [GO:0021801]; corpus callosum development [GO:0022038]; detection of hot stimulus involved in thermoception [GO:0120168]; locomotory behavior [GO:0007626]; microtubule cytoskeleton organization [GO:0000226]; motor behavior [GO:0061744]; negative regulation of microtubule depolymerization [GO:0007026]; neural precursor cell proliferation [GO:0061351]; neuron projection development [GO:0031175]; neuronal stem cell population maintenance [GO:0097150] GO:0000226; GO:0005737; GO:0005874; GO:0006914; GO:0007026; GO:0007420; GO:0007626; GO:0008344; GO:0021801; GO:0021960; GO:0021987; GO:0022038; GO:0030424; GO:0030425; GO:0030426; GO:0031175; GO:0043005; GO:0043025; GO:0044877; GO:0047485; GO:0061351; GO:0061744; GO:0097150; GO:0120168 35202 FUN_043010 1228 1314 437 538 691 ptg000047l:2940046-2953221 Q8CGF6 3.46e-27 WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; anterior commissure morphogenesis [GO:0021960]; autophagy [GO:0006914]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; cerebral cortex radial glia-guided migration [GO:0021801]; corpus callosum development [GO:0022038]; detection of hot stimulus involved in thermoception [GO:0120168]; locomotory behavior [GO:0007626]; microtubule cytoskeleton organization [GO:0000226]; motor behavior [GO:0061744]; negative regulation of microtubule depolymerization [GO:0007026]; neural precursor cell proliferation [GO:0061351]; neuron projection development [GO:0031175]; neuronal stem cell population maintenance [GO:0097150] GO:0000226; GO:0005737; GO:0005874; GO:0006914; GO:0007026; GO:0007420; GO:0007626; GO:0008344; GO:0021801; GO:0021960; GO:0021987; GO:0022038; GO:0030424; GO:0030425; GO:0030426; GO:0031175; GO:0043005; GO:0043025; GO:0044877; GO:0047485; GO:0061351; GO:0061744; GO:0097150; GO:0120168 35203 FUN_043010 1228 1314 437 538 691 ptg000047l:2940046-2953221 Q8CGF6 5.66e-24 WD repeat-containing protein 47 (Neuronal enriched MAP interacting protein) (Nemitin) Mus musculus (Mouse) adult locomotory behavior [GO:0008344]; anterior commissure morphogenesis [GO:0021960]; autophagy [GO:0006914]; brain development [GO:0007420]; cerebral cortex development [GO:0021987]; cerebral cortex radial glia-guided migration [GO:0021801]; corpus callosum development [GO:0022038]; detection of hot stimulus involved in thermoception [GO:0120168]; locomotory behavior [GO:0007626]; microtubule cytoskeleton organization [GO:0000226]; motor behavior [GO:0061744]; negative regulation of microtubule depolymerization [GO:0007026]; neural precursor cell proliferation [GO:0061351]; neuron projection development [GO:0031175]; neuronal stem cell population maintenance [GO:0097150] GO:0000226; GO:0005737; GO:0005874; GO:0006914; GO:0007026; GO:0007420; GO:0007626; GO:0008344; GO:0021801; GO:0021960; GO:0021987; GO:0022038; GO:0030424; GO:0030425; GO:0030426; GO:0031175; GO:0043005; GO:0043025; GO:0044877; GO:0047485; GO:0061351; GO:0061744; GO:0097150; GO:0120168 35204 FUN_043011 342 542 307 663 747 ptg000047l:2955005-2957465 Q5TJE1 4.55e-31 Death domain-associated protein 6 (Daxx) Canis lupus familiaris (Dog) (Canis familiaris) androgen receptor signaling pathway [GO:0030521]; cellular response to cadmium ion [GO:0071276]; cellular response to copper ion [GO:0071280]; cellular response to diamide [GO:0072738]; cellular response to heat [GO:0034605]; cellular response to sodium arsenite [GO:1903936]; cellular response to unfolded protein [GO:0034620]; extrinsic apoptotic signaling pathway via death domain receptors [GO:0008625]; JNK cascade [GO:0007254]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; nucleosome assembly [GO:0006334]; positive regulation of neuron death [GO:1901216]; positive regulation of protein kinase activity [GO:0045860]; regulation of apoptotic process [GO:0042981]; regulation of protein ubiquitination [GO:0031396] GO:0000775; GO:0002039; GO:0003713; GO:0003714; GO:0005634; GO:0005730; GO:0005829; GO:0006334; GO:0007254; GO:0008625; GO:0010629; GO:0016605; GO:0019901; GO:0030295; GO:0030521; GO:0031396; GO:0031625; GO:0034605; GO:0034620; GO:0042393; GO:0042803; GO:0042981; GO:0045860; GO:0045892; GO:0047485; GO:0050681; GO:0061629; GO:0071276; GO:0071280; GO:0072738; GO:0140037; GO:0140416; GO:1901216; GO:1903936 35205 FUN_013628 437 392 170 299 513 NA NA NA NA NA NA NA 35206 FUN_013629 5 1 0 10 0 NA NA NA NA NA NA NA 35207 FUN_013620 14908 16088 8029 10906 8480 ptg000008l:24617004-24637559 A9BUC4 5.54e-27 Urease subunit alpha (EC 3.5.1.5) (Urea amidohydrolase subunit alpha) Delftia acidovorans (strain DSM 14801 / SPH-1) urea catabolic process [GO:0043419] GO:0005737; GO:0009039; GO:0016151; GO:0043419 35208 FUN_013621 2854 3169 2351 2978 2435 ptg000008l:24639116-24639703 P63172 1e-69 Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; intracellular transport of viral protein in host cell [GO:0019060]; microtubule-based movement [GO:0007018]; microtubule-dependent intracellular transport of viral material towards nucleus [GO:0075521]; negative regulation of neurogenesis [GO:0050768]; nervous system development [GO:0007399]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; viral entry into host cell [GO:0046718] GO:0000132; GO:0005576; GO:0005737; GO:0005794; GO:0005819; GO:0005868; GO:0005881; GO:0007018; GO:0007399; GO:0008277; GO:0019060; GO:0030286; GO:0034774; GO:0042802; GO:0043657; GO:0045505; GO:0046718; GO:0050768; GO:0051301; GO:0075521; GO:0099503; GO:1904813 35209 FUN_013622 954 853 432 690 905 NA NA NA NA NA NA NA 35210 FUN_013623 2125 3428 1222 1069 900 NA NA NA NA NA NA NA 35211 FUN_013624 1754 1182 804 874 811 NA NA NA NA NA NA NA 35212 FUN_013625 585 666 368 534 532 NA NA NA NA NA NA NA 35213 FUN_013626 876 681 528 700 504 ptg000008l:24675512-24693486 Q4V7C6 3.46e-26 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase) Rattus norvegicus (Rat) glutamine metabolic process [GO:0006541]; GMP biosynthetic process [GO:0006177]; GMP salvage [GO:0032263]; response to L-cysteine [GO:1901367]; response to xenobiotic stimulus [GO:0009410] GO:0003921; GO:0003922; GO:0005524; GO:0005829; GO:0006177; GO:0006541; GO:0009410; GO:0019899; GO:0032263; GO:1901367 35214 FUN_013627 81 50 72 100 123 NA NA NA NA NA NA NA 35215 FUN_009641 1610 1164 908 1902 1397 ptg000004l:9844977-9883330 A6N6J5 2.14e-22 WD repeat-containing protein 35 (Naofen) Rattus norvegicus (Rat) cellular response to glucose stimulus [GO:0071333]; cellular response to leukemia inhibitory factor [GO:1990830]; cellular response to tumor necrosis factor [GO:0071356]; cellular response to xenobiotic stimulus [GO:0071466]; cilium assembly [GO:0060271]; intraciliary retrograde transport [GO:0035721]; intraciliary transport [GO:0042073]; liver regeneration [GO:0097421]; negative regulation of gene expression [GO:0010629]; negative regulation of nitric oxide biosynthetic process [GO:0045019]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of release of cytochrome c from mitochondria [GO:0090200]; positive regulation of vasoconstriction [GO:0045907]; protein localization to cilium [GO:0061512]; response to lipopolysaccharide [GO:0032496]; response to toxic substance [GO:0009636] GO:0005737; GO:0005813; GO:0005930; GO:0009636; GO:0010629; GO:0030991; GO:0032496; GO:0035721; GO:0036064; GO:0042073; GO:0043065; GO:0043280; GO:0045019; GO:0045907; GO:0060271; GO:0061512; GO:0071333; GO:0071356; GO:0071466; GO:0090200; GO:0097421; GO:1990830 35216 FUN_009640 1770 1294 727 2074 966 NA NA NA NA NA NA NA 35217 FUN_009645 187 466 209 248 159 NA NA NA NA NA NA NA 35218 FUN_009644 1235 2005 565 533 587 NA NA NA NA NA NA NA 35219 FUN_009647 1664 1004 849 1121 1076 NA NA NA NA NA NA NA 35220 FUN_009646 173 128 144 127 142 NA NA NA NA NA NA NA 35221 FUN_009649 187 94 112 211 127 ptg000004l:9953227-9956050 P48442 4.02e-99 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 35222 FUN_009648 190 51 39 45 28 ptg000004l:9943518-9948087 O62714 4.8e-67 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) Sus scrofa (Pig) cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of calcium ion transport [GO:0051924] GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006874; GO:0007186; GO:0016597; GO:0042803; GO:0051924 35223 FUN_009648 190 51 39 45 28 ptg000004l:9943518-9948087 O62714 4.01e-50 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) Sus scrofa (Pig) cellular calcium ion homeostasis [GO:0006874]; detection of calcium ion [GO:0005513]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of calcium ion transport [GO:0051924] GO:0004930; GO:0005509; GO:0005513; GO:0005886; GO:0006874; GO:0007186; GO:0016597; GO:0042803; GO:0051924 35224 FUN_007922 3281 3299 979 1536 757 NA NA NA NA NA NA NA 35225 FUN_029548 13 0 47 0 28 NA NA NA NA NA NA NA 35226 FUN_029549 1185 649 1350 220 989 NA NA NA NA NA NA NA 35227 FUN_029544 270 0 54 127 194 NA NA NA NA NA NA NA 35228 FUN_029545 184 162 106 410 102 NA NA NA NA NA NA NA 35229 FUN_029546 0 15 28 44 23 NA NA NA NA NA NA NA 35230 FUN_029547 1033 621 468 494 572 NA NA NA NA NA NA NA 35231 FUN_029540 146 18 47 23 27 ptg000023l:3123113-3126142 Q9N126 2.32e-21 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 35232 FUN_029541 1272 524 435 527 324 ptg000023l:3127970-3132846 Q9N126 5.8e-21 Retinol dehydrogenase 8 (EC 1.1.1.300) (Photoreceptor outer segment all-trans retinol dehydrogenase) Bos taurus (Bovine) estrogen biosynthetic process [GO:0006703]; response to stimulus [GO:0050896]; retinol metabolic process [GO:0042572]; visual perception [GO:0007601] GO:0004303; GO:0004745; GO:0005829; GO:0006703; GO:0007601; GO:0016491; GO:0042572; GO:0042622; GO:0050896; GO:0052650 35233 FUN_029542 802 141 315 856 536 NA NA NA NA NA NA NA 35234 FUN_029543 0 54 0 4 0 ptg000023l:3152744-3154091 Q49SH1 1.07e-62 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 35235 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 1.59e-58 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35236 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 3.77e-58 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35237 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 5.3e-54 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35238 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 6.68e-53 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35239 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 1.47e-52 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35240 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 3.87e-51 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35241 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 2.92e-49 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35242 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 4.18e-39 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35243 FUN_026251 69 3 11 0 21 ptg000020l:6754743-6756365 P16157 1.12e-29 Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin) Homo sapiens (Human) cytoskeleton organization [GO:0007010]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; exocytosis [GO:0006887]; maintenance of epithelial cell apical/basal polarity [GO:0045199]; protein localization to plasma membrane [GO:0072659]; signal transduction [GO:0007165] GO:0005198; GO:0005200; GO:0005829; GO:0005856; GO:0005886; GO:0006887; GO:0006888; GO:0007010; GO:0007165; GO:0008093; GO:0009898; GO:0014731; GO:0016323; GO:0016529; GO:0019899; GO:0019903; GO:0030507; GO:0031430; GO:0043005; GO:0044325; GO:0045199; GO:0051117; GO:0072659 35244 FUN_026250 116 0 43 71 0 NA NA NA NA NA NA NA 35245 FUN_026252 722 66 19 71 65 NA NA NA NA NA NA NA 35246 FUN_026255 2097 469 636 3 1083 ptg000020l:6795045-6798849 Q5ZLC8 1.17e-110 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 35247 FUN_026255 2097 469 636 3 1083 ptg000020l:6795045-6798849 Q5ZLC8 1.5e-101 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 35248 FUN_026255 2097 469 636 3 1083 ptg000020l:6795045-6798849 Q5ZLC8 6.83e-95 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 35249 FUN_026255 2097 469 636 3 1083 ptg000020l:6795045-6798849 Q5ZLC8 9.75e-72 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 35250 FUN_026255 2097 469 636 3 1083 ptg000020l:6795045-6798849 Q5ZLC8 7.57e-69 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 35251 FUN_026255 2097 469 636 3 1083 ptg000020l:6795045-6798849 Q5ZLC8 1.14e-44 Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) Gallus gallus (Chicken) protein localization to T-tubule [GO:0036371]; regulation of cardiac muscle contraction [GO:0055117] GO:0030315; GO:0036371; GO:0055117 35252 FUN_026257 150 38 15 57 94 ptg000020l:6808912-6818601 Q9EQG6 8.12e-27 Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein) Rattus norvegicus (Rat) cellular response to nerve growth factor stimulus [GO:1990090]; dendrite morphogenesis [GO:0048813]; in utero embryonic development [GO:0001701]; nerve growth factor signaling pathway [GO:0038180]; positive regulation of neuron projection development [GO:0010976] GO:0001701; GO:0005770; GO:0005829; GO:0010976; GO:0016020; GO:0019887; GO:0019901; GO:0030165; GO:0032991; GO:0038180; GO:0048813; GO:1990090 35253 FUN_026256 619 118 154 234 97 NA NA NA NA NA NA NA 35254 FUN_026259 12 2 15 0 22 ptg000020l:6851706-6857626 Q4UMH6 8.65e-60 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 35255 FUN_026259 12 2 15 0 22 ptg000020l:6851706-6857626 Q4UMH6 2.51e-54 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 35256 FUN_026259 12 2 15 0 22 ptg000020l:6851706-6857626 Q4UMH6 1.18e-50 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 35257 FUN_026259 12 2 15 0 22 ptg000020l:6851706-6857626 Q4UMH6 7.77e-45 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 35258 FUN_026259 12 2 15 0 22 ptg000020l:6851706-6857626 Q4UMH6 3.47e-44 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 35259 FUN_026259 12 2 15 0 22 ptg000020l:6851706-6857626 Q4UMH6 4.59e-34 Putative ankyrin repeat protein RF_0381 Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi) guanosine tetraphosphate metabolic process [GO:0015969] GO:0015969 35260 FUN_026258 0 0 0 0 25 ptg000020l:6831342-6850437 Q9NBX4 8.9e-21 Probable RNA-directed DNA polymerase from transposon X-element (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 35261 FUN_007923 9241 8821 4320 7865 5336 NA NA NA NA NA NA NA 35262 FUN_040379 0 16 0 11 43 NA NA NA NA NA NA NA 35263 FUN_004134 197 47 249 145 116 NA NA NA NA NA NA NA 35264 FUN_040377 17 48 0 0 108 NA NA NA NA NA NA NA 35265 FUN_004136 72 55 93 0 79 NA NA NA NA NA NA NA 35266 FUN_004137 38 31 95 75 44 NA NA NA NA NA NA NA 35267 FUN_032749 20 0 26 0 165 ptg000023l:35570894-35578752 Q6QME8 2.88e-79 Protein argonaute-2 (Argonaute2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Protein slicer) Bos taurus (Bovine) miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; miRNA-mediated gene silencing by mRNA destabilization [GO:0035279]; negative regulation of translational initiation [GO:0045947]; pre-miRNA processing [GO:0031054]; regulation of DNA-templated transcription [GO:0006355] GO:0000340; GO:0000932; GO:0005634; GO:0005844; GO:0005845; GO:0006355; GO:0016442; GO:0031054; GO:0035197; GO:0035198; GO:0035278; GO:0035279; GO:0045947; GO:0046872; GO:0070551; GO:0070578; GO:1990904 35268 FUN_010452 124 38 26 130 20 NA NA NA NA NA NA NA 35269 FUN_010453 50 0 0 79 0 NA NA NA NA NA NA NA 35270 FUN_040370 6 0 2 24 18 NA NA NA NA NA NA NA 35271 FUN_010451 29 21 0 18 0 NA NA NA NA NA NA NA 35272 FUN_023555 512 360 277 295 213 ptg000017l:9034932-9042511 Q9UIF7 6.4e-73 Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH) Homo sapiens (Human) base-excision repair [GO:0006284]; depurination [GO:0045007]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; negative regulation of necroptotic process [GO:0060546] GO:0000701; GO:0005634; GO:0005654; GO:0005739; GO:0006281; GO:0006284; GO:0006298; GO:0019104; GO:0032357; GO:0032407; GO:0034039; GO:0035485; GO:0045007; GO:0046872; GO:0051539; GO:0060546 35273 FUN_023555 512 360 277 295 213 ptg000017l:9034932-9042511 Q9UIF7 4.08e-37 Adenine DNA glycosylase (EC 3.2.2.31) (MutY homolog) (hMYH) Homo sapiens (Human) base-excision repair [GO:0006284]; depurination [GO:0045007]; DNA repair [GO:0006281]; mismatch repair [GO:0006298]; negative regulation of necroptotic process [GO:0060546] GO:0000701; GO:0005634; GO:0005654; GO:0005739; GO:0006281; GO:0006284; GO:0006298; GO:0019104; GO:0032357; GO:0032407; GO:0034039; GO:0035485; GO:0045007; GO:0046872; GO:0051539; GO:0060546 35274 FUN_023554 846 565 496 586 505 ptg000017l:9024478-9029924 Q6GM44 2.85e-104 E3 ubiquitin-protein ligase MARCHF5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (RING-type E3 ubiquitin transferase MARCHF5) Xenopus laevis (African clawed frog) protein autoubiquitination [GO:0051865]; regulation of mitochondrial fission [GO:0090140] GO:0005741; GO:0005783; GO:0005789; GO:0008270; GO:0051865; GO:0061630; GO:0090140 35275 FUN_023557 1189 483 590 971 1098 NA NA NA NA NA NA NA 35276 FUN_023556 1314 934 1012 1845 1756 NA NA NA NA NA NA NA 35277 FUN_023551 47056 28113 32947 26278 19885 NA NA NA NA NA NA NA 35278 FUN_023550 1189 1358 886 1063 778 ptg000017l:8959809-8967169 Q2HIW2 2.93e-44 Membrane-associated progesterone-binding protein 4 (AtMAPR4) Arabidopsis thaliana (Mouse-ear cress) NA GO:0005496; GO:0012505; GO:0016020 35279 FUN_023553 403 273 140 309 194 ptg000017l:9011263-9023052 Q9VSR3 1.62e-35 Translational regulator orb2 Drosophila melanogaster (Fruit fly) asymmetric cell division [GO:0008356]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; male meiosis I [GO:0007141]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of translation [GO:0017148]; positive regulation of translation [GO:0045727]; protein stabilization [GO:0050821]; sperm axoneme assembly [GO:0007288]; sperm individualization [GO:0007291]; spermatogenesis [GO:0007283] GO:0000900; GO:0003723; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0005938; GO:0007141; GO:0007283; GO:0007288; GO:0007291; GO:0007616; GO:0008049; GO:0008135; GO:0008356; GO:0008494; GO:0017148; GO:0030424; GO:0032991; GO:0042802; GO:0043005; GO:0043022; GO:0043204; GO:0043679; GO:0044292; GO:0044297; GO:0045202; GO:0045727; GO:0048471; GO:0050821; GO:0097060; GO:0098793; GO:0098794; GO:1990124; GO:2000766 35280 FUN_023553 403 273 140 309 194 ptg000017l:9011263-9023052 Q9VSR3 2.18e-26 Translational regulator orb2 Drosophila melanogaster (Fruit fly) asymmetric cell division [GO:0008356]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; male meiosis I [GO:0007141]; negative regulation of cytoplasmic translation [GO:2000766]; negative regulation of translation [GO:0017148]; positive regulation of translation [GO:0045727]; protein stabilization [GO:0050821]; sperm axoneme assembly [GO:0007288]; sperm individualization [GO:0007291]; spermatogenesis [GO:0007283] GO:0000900; GO:0003723; GO:0003730; GO:0005634; GO:0005737; GO:0005829; GO:0005938; GO:0007141; GO:0007283; GO:0007288; GO:0007291; GO:0007616; GO:0008049; GO:0008135; GO:0008356; GO:0008494; GO:0017148; GO:0030424; GO:0032991; GO:0042802; GO:0043005; GO:0043022; GO:0043204; GO:0043679; GO:0044292; GO:0044297; GO:0045202; GO:0045727; GO:0048471; GO:0050821; GO:0097060; GO:0098793; GO:0098794; GO:1990124; GO:2000766 35281 FUN_023552 571 294 67 186 266 ptg000017l:8985299-8998380 Q3TX08 2.57e-23 tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase) Mus musculus (Mouse) tRNA N2-guanine methylation [GO:0002940] GO:0000049; GO:0002940; GO:0004809; GO:0005634; GO:0046872 35282 FUN_023559 1314 1553 758 1257 902 NA NA NA NA NA NA NA 35283 FUN_023558 3065 3370 1464 2341 2686 NA NA NA NA NA NA NA 35284 FUN_008996 72 51 48 87 141 NA NA NA NA NA NA NA 35285 FUN_008997 2954 1658 1176 2911 2084 NA NA NA NA NA NA NA 35286 FUN_008994 968 898 606 1002 507 ptg000004l:1252301-1266615 P21328 4.87e-45 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 35287 FUN_008995 29859 31528 14593 31552 29160 ptg000004l:1267114-1269751 Q962U2 1.59e-42 60S ribosomal protein L11 Spodoptera frugiperda (Fall armyworm) translation [GO:0006412] GO:0003735; GO:0005634; GO:0005737; GO:0005840; GO:0006412; GO:0019843; GO:1990904 35288 FUN_008992 64 193 16 88 64 ptg000004l:1230785-1232515 Q91611 1.67e-30 Desert hedgehog protein B (EC 3.1.-.-) (Desert hedgehog protein 2) (DHH-2) (Hedgehog protein 4) (X-HH4) [Cleaved into: Desert hedgehog protein B N-product] Xenopus laevis (African clawed frog) cell-cell signaling [GO:0007267]; positive regulation of smoothened signaling pathway [GO:0045880]; protein autoprocessing [GO:0016540]; self proteolysis [GO:0097264] GO:0000139; GO:0005113; GO:0005576; GO:0005789; GO:0005886; GO:0007267; GO:0008233; GO:0016540; GO:0045880; GO:0046872; GO:0097264; GO:0140853 35289 FUN_008993 5149 3964 2835 8385 7332 NA NA NA NA NA NA NA 35290 FUN_008990 43 13 0 26 10 NA NA NA NA NA NA NA 35291 FUN_008991 6491 5155 3918 6310 6548 ptg000004l:1218493-1230251 P46978 2.94e-57 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) Mus musculus (Mouse) co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0004579; GO:0005789; GO:0006487; GO:0008250; GO:0016020; GO:0018279; GO:0035000; GO:0043686; GO:0043687; GO:0046872 35292 FUN_008991 6491 5155 3918 6310 6548 ptg000004l:1218493-1230251 P46978 1.21e-33 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) Mus musculus (Mouse) co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0004579; GO:0005789; GO:0006487; GO:0008250; GO:0016020; GO:0018279; GO:0035000; GO:0043686; GO:0043687; GO:0046872 35293 FUN_008991 6491 5155 3918 6310 6548 ptg000004l:1218493-1230251 P46978 1.51e-25 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) Mus musculus (Mouse) co-translational protein modification [GO:0043686]; post-translational protein modification [GO:0043687]; protein N-linked glycosylation [GO:0006487]; protein N-linked glycosylation via asparagine [GO:0018279] GO:0004579; GO:0005789; GO:0006487; GO:0008250; GO:0016020; GO:0018279; GO:0035000; GO:0043686; GO:0043687; GO:0046872 35294 FUN_008998 16414 21444 8134 13857 3614 NA NA NA NA NA NA NA 35295 FUN_008999 0 15 0 9 0 NA NA NA NA NA NA NA 35296 FUN_025786 4030 3045 2256 3616 3408 ptg000020l:678979-691348 Q8VHI3 2.65e-64 GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) Mus musculus (Mouse) fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; mesoderm formation [GO:0001707]; positive regulation of protein folding [GO:1903334]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046] GO:0001707; GO:0005783; GO:0005794; GO:0006004; GO:0008417; GO:0010468; GO:0010717; GO:0036065; GO:0036066; GO:0046922; GO:0051046; GO:1903334 35297 FUN_025786 4030 3045 2256 3616 3408 ptg000020l:678979-691348 Q8VHI3 3.07e-23 GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) Mus musculus (Mouse) fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; mesoderm formation [GO:0001707]; positive regulation of protein folding [GO:1903334]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046] GO:0001707; GO:0005783; GO:0005794; GO:0006004; GO:0008417; GO:0010468; GO:0010717; GO:0036065; GO:0036066; GO:0046922; GO:0051046; GO:1903334 35298 FUN_025786 4030 3045 2256 3616 3408 ptg000020l:678979-691348 Q8VHI3 2.47e-22 GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) Mus musculus (Mouse) fucose metabolic process [GO:0006004]; fucosylation [GO:0036065]; mesoderm formation [GO:0001707]; positive regulation of protein folding [GO:1903334]; protein O-linked fucosylation [GO:0036066]; regulation of epithelial to mesenchymal transition [GO:0010717]; regulation of gene expression [GO:0010468]; regulation of secretion [GO:0051046] GO:0001707; GO:0005783; GO:0005794; GO:0006004; GO:0008417; GO:0010468; GO:0010717; GO:0036065; GO:0036066; GO:0046922; GO:0051046; GO:1903334 35299 FUN_025787 622 461 252 471 359 NA NA NA NA NA NA NA 35300 FUN_025784 3162 1507 1406 2841 3752 NA NA NA NA NA NA NA 35301 FUN_025785 37 14 15 36 56 NA NA NA NA NA NA NA 35302 FUN_025782 36840 38016 20164 34030 25358 NA NA NA NA NA NA NA 35303 FUN_025783 13 19 35 74 31 NA NA NA NA NA NA NA 35304 FUN_025780 6652 8026 5327 7185 7666 ptg000020l:650087-655467 O02649 2.27e-49 Heat shock protein 60A Drosophila melanogaster (Fruit fly) apoptotic mitochondrial changes [GO:0008637]; cellular response to heat [GO:0034605]; mitochondrial unfolded protein response [GO:0034514]; mitochondrion organization [GO:0007005]; protein folding [GO:0006457]; protein import into mitochondrial intermembrane space [GO:0045041]; protein refolding [GO:0042026] GO:0005524; GO:0005739; GO:0005743; GO:0005759; GO:0006457; GO:0007005; GO:0008637; GO:0016887; GO:0034514; GO:0034605; GO:0042026; GO:0045041; GO:0051087; GO:0140662 35305 FUN_025780 6652 8026 5327 7185 7666 ptg000020l:650087-655467 O02649 1.98e-42 Heat shock protein 60A Drosophila melanogaster (Fruit fly) apoptotic mitochondrial changes [GO:0008637]; cellular response to heat [GO:0034605]; mitochondrial unfolded protein response [GO:0034514]; mitochondrion organization [GO:0007005]; protein folding [GO:0006457]; protein import into mitochondrial intermembrane space [GO:0045041]; protein refolding [GO:0042026] GO:0005524; GO:0005739; GO:0005743; GO:0005759; GO:0006457; GO:0007005; GO:0008637; GO:0016887; GO:0034514; GO:0034605; GO:0042026; GO:0045041; GO:0051087; GO:0140662 35306 FUN_025780 6652 8026 5327 7185 7666 ptg000020l:650087-655467 O02649 3.12e-35 Heat shock protein 60A Drosophila melanogaster (Fruit fly) apoptotic mitochondrial changes [GO:0008637]; cellular response to heat [GO:0034605]; mitochondrial unfolded protein response [GO:0034514]; mitochondrion organization [GO:0007005]; protein folding [GO:0006457]; protein import into mitochondrial intermembrane space [GO:0045041]; protein refolding [GO:0042026] GO:0005524; GO:0005739; GO:0005743; GO:0005759; GO:0006457; GO:0007005; GO:0008637; GO:0016887; GO:0034514; GO:0034605; GO:0042026; GO:0045041; GO:0051087; GO:0140662 35307 FUN_018004 4284 4573 1916 2883 1195 ptg000012l:3011566-3019969 Q9JI78 9.47e-25 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) (mPNGase) (EC 3.5.1.52) (N-glycanase 1) (Peptide:N-glycanase) Mus musculus (Mouse) ER-associated misfolded protein catabolic process [GO:0071712]; glycoprotein catabolic process [GO:0006516]; protein deglycosylation [GO:0006517]; protein quality control for misfolded or incompletely synthesized proteins [GO:0006515] GO:0000224; GO:0005634; GO:0005737; GO:0005829; GO:0006515; GO:0006516; GO:0006517; GO:0046872; GO:0062023; GO:0071712 35308 FUN_025788 838 646 541 763 713 NA NA NA NA NA NA NA 35309 FUN_025789 415 395 341 681 436 ptg000020l:702319-723154 Q1PSW8 1.94e-21 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Mus musculus (Mouse) 3'-UTR-mediated mRNA destabilization [GO:0061158]; cellular response to organic substance [GO:0071310]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA processing [GO:0035196]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube closure [GO:0001843]; neural tube development [GO:0021915]; positive regulation of miRNA-mediated gene silencing [GO:2000637]; post-transcriptional regulation of gene expression [GO:0010608]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; regulation of protein metabolic process [GO:0051246]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0001843; GO:0004842; GO:0008270; GO:0008543; GO:0010586; GO:0010608; GO:0017148; GO:0021915; GO:0030371; GO:0035196; GO:0035198; GO:0035278; GO:0043161; GO:0051246; GO:0051865; GO:0060964; GO:0061158; GO:0061630; GO:0071310; GO:0072089; GO:2000177; GO:2000637 35310 FUN_007924 43 28 118 66 111 NA NA NA NA NA NA NA 35311 FUN_027822 0 0 0 0 19 NA NA NA NA NA NA NA 35312 FUN_017620 4 8 0 2 0 NA NA NA NA NA NA NA 35313 FUN_017621 0 9 0 0 0 NA NA NA NA NA NA NA 35314 FUN_017622 6 0 0 0 0 NA NA NA NA NA NA NA 35315 FUN_018001 619 645 171 640 280 NA NA NA NA NA NA NA 35316 FUN_017628 0 0 0 0 17 NA NA NA NA NA NA NA 35317 FUN_017629 0 0 0 0 110 NA NA NA NA NA NA NA 35318 FUN_018000 5100 3636 2970 4062 2584 NA NA NA NA NA NA NA 35319 FUN_026789 8 3 5 12 0 NA NA NA NA NA NA NA 35320 FUN_026788 5 0 7 0 20 NA NA NA NA NA NA NA 35321 FUN_027827 275 0 0 0 0 NA NA NA NA NA NA NA 35322 FUN_026782 18 0 0 0 0 NA NA NA NA NA NA NA 35323 FUN_026784 26 0 0 0 0 NA NA NA NA NA NA NA 35324 FUN_025258 692 1160 598 952 742 NA NA NA NA NA NA NA 35325 FUN_025259 347 183 118 241 450 NA NA NA NA NA NA NA 35326 FUN_022208 1149 670 458 360 496 NA NA NA NA NA NA NA 35327 FUN_022209 696 281 281 802 1194 NA NA NA NA NA NA NA 35328 FUN_022202 58 0 21 8 104 ptg000016l:6278576-6283058 P10181 3.75e-25 Homeobox protein rough Drosophila melanogaster (Fruit fly) establishment of ommatidial planar polarity [GO:0042067]; positive regulation of transcription by RNA polymerase II [GO:0045944]; R2/R5 cell differentiation [GO:0048054]; R2/R5 cell fate commitment [GO:0007463]; regulation of transcription by RNA polymerase II [GO:0006357]; response to stimulus [GO:0050896]; visual perception [GO:0007601] GO:0000977; GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0007463; GO:0007601; GO:0042067; GO:0045944; GO:0048054; GO:0050896 35329 FUN_022203 1164 688 765 989 1104 NA NA NA NA NA NA NA 35330 FUN_025252 1344 196 245 495 352 ptg000019l:438345-439572 Q11126 2.44e-42 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 35331 FUN_022201 136 49 70 142 34 ptg000016l:6273605-6275164 P50219 4.09e-24 Motor neuron and pancreas homeobox protein 1 (Homeobox protein HB9) Homo sapiens (Human) central nervous system development [GO:0007417]; endocrine pancreas development [GO:0031018]; neuron projection morphogenesis [GO:0048812]; spinal cord motor neuron cell fate specification [GO:0021520] GO:0000785; GO:0000981; GO:0001227; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0007417; GO:0021520; GO:0031018; GO:0048812; GO:1990837 35332 FUN_025254 260 53 67 47 51 ptg000019l:451041-452145 Q11126 5.74e-42 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 35333 FUN_022207 0 2 38 3 146 NA NA NA NA NA NA NA 35334 FUN_025256 845 887 770 208 250 ptg000019l:469846-471070 Q8HYJ7 7.41e-41 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 35335 FUN_022205 5965 4788 4466 8024 6400 NA NA NA NA NA NA NA 35336 FUN_024785 2864 3334 1410 5228 3534 NA NA NA NA NA NA NA 35337 FUN_024784 47 52 107 43 207 NA NA NA NA NA NA NA 35338 FUN_024787 82 6 32 46 0 NA NA NA NA NA NA NA 35339 FUN_027721 13 0 0 0 16 NA NA NA NA NA NA NA 35340 FUN_024781 1084 805 666 1280 1410 NA NA NA NA NA NA NA 35341 FUN_024780 1173 1482 876 1692 626 NA NA NA NA NA NA NA 35342 FUN_024783 177 97 102 154 265 ptg000018l:11020737-11029045 Q6NUT3 7.69e-30 Major facilitator superfamily domain-containing protein 12 Homo sapiens (Human) carbohydrate transport [GO:0008643]; cysteine transmembrane transport [GO:1903712]; melanin biosynthetic process [GO:0042438]; negative regulation of melanin biosynthetic process [GO:0048022]; organic substance transport [GO:0071702]; pigment metabolic process involved in pigmentation [GO:0043474]; regulation of melanin biosynthetic process [GO:0048021] GO:0005764; GO:0005765; GO:0005770; GO:0005886; GO:0008643; GO:0015293; GO:0033162; GO:0033229; GO:0042438; GO:0042470; GO:0043474; GO:0048021; GO:0048022; GO:0071702; GO:1903712 35343 FUN_024721 233 313 179 392 310 ptg000018l:10280854-10281769 P13913 7.45e-31 Arylamine N-acetyltransferase, pineal gland isozyme NAT-10 (Arylamine acetylase) (EC 2.3.1.5) Gallus gallus (Chicken) NA GO:0004060 35344 FUN_019508 55 13 40 67 118 NA NA NA NA NA NA NA 35345 FUN_019501 314 165 135 135 596 NA NA NA NA NA NA NA 35346 FUN_019507 0 20 54 154 109 NA NA NA NA NA NA NA 35347 FUN_019506 0 0 2 10 8 NA NA NA NA NA NA NA 35348 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 1.94e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35349 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 6.33e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35350 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 9.7e-123 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35351 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 6.89e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35352 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 3.58e-119 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35353 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 3.79e-111 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35354 FUN_019505 723 432 896 1784 1275 ptg000015l:2929211-2932980 Q96AY4 1.82e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35355 FUN_019504 23 0 0 24 0 NA NA NA NA NA NA NA 35356 FUN_028051 201 65 54 133 57 NA NA NA NA NA NA NA 35357 FUN_036879 7394 5125 3095 6061 3020 ptg000026l:3019124-3030733 Q60967 1.56e-56 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Mus musculus (Mouse) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0005829; GO:0009336; GO:0016310; GO:0016779; GO:0042803; GO:0050428 35358 FUN_036879 7394 5125 3095 6061 3020 ptg000026l:3019124-3030733 Q60967 9.02e-31 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Mus musculus (Mouse) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0005829; GO:0009336; GO:0016310; GO:0016779; GO:0042803; GO:0050428 35359 FUN_036879 7394 5125 3095 6061 3020 ptg000026l:3019124-3030733 Q60967 2e-26 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Mus musculus (Mouse) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0005829; GO:0009336; GO:0016310; GO:0016779; GO:0042803; GO:0050428 35360 FUN_036879 7394 5125 3095 6061 3020 ptg000026l:3019124-3030733 Q60967 3.35e-23 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Mus musculus (Mouse) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0005829; GO:0009336; GO:0016310; GO:0016779; GO:0042803; GO:0050428 35361 FUN_036879 7394 5125 3095 6061 3020 ptg000026l:3019124-3030733 Q60967 3.35e-23 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPS synthase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK 1) (SK1) [Includes: Sulfate adenylyltransferase (EC 2.7.7.4) (ATP-sulfurylase) (Sulfate adenylate transferase) (SAT); Adenylyl-sulfate kinase (EC 2.7.1.25) (3'-phosphoadenosine-5'-phosphosulfate synthase) (APS kinase) (Adenosine-5'-phosphosulfate 3'-phosphotransferase) (Adenylylsulfate 3'-phosphotransferase)] Mus musculus (Mouse) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process [GO:0050428]; phosphorylation [GO:0016310]; sulfate assimilation [GO:0000103] GO:0000103; GO:0004020; GO:0004781; GO:0005524; GO:0005829; GO:0009336; GO:0016310; GO:0016779; GO:0042803; GO:0050428 35362 FUN_023005 1709 1749 784 1666 966 NA NA NA NA NA NA NA 35363 FUN_024129 1583 870 851 2205 1218 NA NA NA NA NA NA NA 35364 FUN_024128 25 13 54 68 53 ptg000018l:2389836-2400468 P10978 1.15e-25 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 35365 FUN_024128 25 13 54 68 53 ptg000018l:2389836-2400468 P10978 1.15e-25 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 35366 FUN_024128 25 13 54 68 53 ptg000018l:2389836-2400468 P10978 1.15e-25 Retrovirus-related Pol polyprotein from transposon TNT 1-94 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Nicotiana tabacum (Common tobacco) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0008270; GO:0015074 35367 FUN_028052 23 13 0 28 14 NA NA NA NA NA NA NA 35368 FUN_023305 1215 2576 1616 1603 2358 ptg000017l:6077413-6082857 P49354 1.89e-31 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) Homo sapiens (Human) neurotransmitter receptor metabolic process [GO:0045213]; positive regulation of deacetylase activity [GO:0090045]; positive regulation of tubulin deacetylation [GO:0090044]; protein farnesylation [GO:0018343]; protein geranylgeranylation [GO:0018344]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0004660; GO:0004661; GO:0004662; GO:0004663; GO:0005737; GO:0005829; GO:0005875; GO:0005886; GO:0005953; GO:0005965; GO:0007179; GO:0008017; GO:0018343; GO:0018344; GO:0030548; GO:0030971; GO:0043014; GO:0045213; GO:0060090; GO:0071340; GO:0090044; GO:0090045 35369 FUN_024121 160 312 122 317 103 NA NA NA NA NA NA NA 35370 FUN_024120 27 83 93 100 29 NA NA NA NA NA NA NA 35371 FUN_024123 1673 1592 952 2326 1690 NA NA NA NA NA NA NA 35372 FUN_024122 301 446 172 303 101 NA NA NA NA NA NA NA 35373 FUN_024124 18298 22831 9081 21688 16398 NA NA NA NA NA NA NA 35374 FUN_024127 3974 3587 2677 3481 1967 NA NA NA NA NA NA NA 35375 FUN_030658 1794 1773 1144 1743 1441 NA NA NA NA NA NA NA 35376 FUN_030659 1096 586 472 786 776 NA NA NA NA NA NA NA 35377 FUN_030656 944 1140 703 1031 1005 ptg000023l:14351005-14402763 Q0V9S9 7.44e-24 Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) flagellated sperm motility [GO:0030317]; sperm axoneme assembly [GO:0007288]; spermatogenesis [GO:0007283] GO:0005737; GO:0005856; GO:0007283; GO:0007288; GO:0030317; GO:0031514 35378 FUN_030657 0 0 0 36 0 NA NA NA NA NA NA NA 35379 FUN_030655 776 233 376 257 383 NA NA NA NA NA NA NA 35380 FUN_030652 17 47 22 0 4 NA NA NA NA NA NA NA 35381 FUN_023303 340 127 188 176 188 NA NA NA NA NA NA NA 35382 FUN_031650 683 530 328 1456 426 ptg000023l:23901692-23906081 Q9QZU7 3.22e-25 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 35383 FUN_023009 37347 22265 17093 44439 19345 ptg000017l:2611884-2617523 Q5MCW4 5.51e-38 Zinc finger protein 569 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35384 FUN_023009 37347 22265 17093 44439 19345 ptg000017l:2611884-2617523 Q5MCW4 3.72e-29 Zinc finger protein 569 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35385 FUN_023009 37347 22265 17093 44439 19345 ptg000017l:2611884-2617523 Q5MCW4 3.55e-28 Zinc finger protein 569 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35386 FUN_023009 37347 22265 17093 44439 19345 ptg000017l:2611884-2617523 Q5MCW4 3.91e-27 Zinc finger protein 569 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35387 FUN_023009 37347 22265 17093 44439 19345 ptg000017l:2611884-2617523 Q5MCW4 1.56e-23 Zinc finger protein 569 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35388 FUN_023009 37347 22265 17093 44439 19345 ptg000017l:2611884-2617523 Q5MCW4 9.65e-22 Zinc finger protein 569 Homo sapiens (Human) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0005634; GO:0006357; GO:0046872 35389 FUN_036877 185 75 252 501 1005 NA NA NA NA NA NA NA 35390 FUN_025464 525 126 226 322 383 ptg000019l:3023074-3029429 P60764 3.64e-25 Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3) Mus musculus (Mouse) actin cytoskeleton organization [GO:0030036]; actin filament organization [GO:0007015]; cell projection assembly [GO:0030031]; cerebral cortex GABAergic interneuron development [GO:0021894]; cortical cytoskeleton organization [GO:0030865]; establishment or maintenance of cell polarity [GO:0007163]; homeostasis of number of cells within a tissue [GO:0048873]; neuromuscular process [GO:0050905]; neuromuscular process controlling balance [GO:0050885]; neuron projection development [GO:0031175]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; regulation of neuron maturation [GO:0014041]; small GTPase mediated signal transduction [GO:0007264]; synaptic transmission, GABAergic [GO:0051932]; Wnt signaling pathway [GO:0016055] GO:0003924; GO:0003925; GO:0005525; GO:0005829; GO:0005856; GO:0005886; GO:0005938; GO:0007015; GO:0007163; GO:0007264; GO:0008360; GO:0012505; GO:0014041; GO:0016055; GO:0019901; GO:0021894; GO:0022604; GO:0030027; GO:0030031; GO:0030036; GO:0030426; GO:0030865; GO:0031175; GO:0031410; GO:0031941; GO:0032956; GO:0033630; GO:0042995; GO:0043005; GO:0043025; GO:0048306; GO:0048471; GO:0048873; GO:0050885; GO:0050905; GO:0051932; GO:0071944; GO:0098974; GO:0098978; GO:1900026 35391 FUN_015089 2435 1428 1293 1985 1619 NA NA NA NA NA NA NA 35392 FUN_015082 245 99 86 178 195 ptg000009l:5942649-5944317 Q8HYJ7 2.24e-45 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 35393 FUN_015083 67 15 20 53 53 NA NA NA NA NA NA NA 35394 FUN_015080 51 23 29 85 89 NA NA NA NA NA NA NA 35395 FUN_015081 218 78 67 159 186 ptg000009l:5938616-5939660 Q8HYJ7 3.97e-47 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 (EC 2.4.1.152) (3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5) (EC 2.4.1.65) (Fucosyltransferase 5) (Fucosyltransferase V) (Fuc-TV) (FucT-V) (Galactoside 3-L-fucosyltransferase) Gorilla gorilla gorilla (Western lowland gorilla) ceramide metabolic process [GO:0006672]; fucosylation [GO:0036065]; oligosaccharide metabolic process [GO:0009311]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0006487; GO:0006493; GO:0006672; GO:0009311; GO:0017060; GO:0017083; GO:0032580; GO:0036065; GO:0046920 35396 FUN_015086 327 522 142 336 489 ptg000009l:5967503-5975495 P12265 6.74e-31 Beta-glucuronidase (EC 3.2.1.31) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] GO:0004566; GO:0005102; GO:0005615; GO:0005764; GO:0005783; GO:0005975; GO:0016787; GO:0019391; GO:0019904; GO:0030200; GO:0030207; GO:0030214; GO:0030246; GO:0043202; GO:0043231 35397 FUN_015086 327 522 142 336 489 ptg000009l:5967503-5975495 P12265 6.74e-31 Beta-glucuronidase (EC 3.2.1.31) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] GO:0004566; GO:0005102; GO:0005615; GO:0005764; GO:0005783; GO:0005975; GO:0016787; GO:0019391; GO:0019904; GO:0030200; GO:0030207; GO:0030214; GO:0030246; GO:0043202; GO:0043231 35398 FUN_015087 1361 1130 779 1086 1525 ptg000009l:5976099-5982391 Q4FAT7 1.44e-23 Beta-glucuronidase (EC 3.2.1.31) Sus scrofa (Pig) chondroitin sulfate catabolic process [GO:0030207]; glucuronoside catabolic process [GO:0019391]; heparan sulfate proteoglycan catabolic process [GO:0030200]; hyaluronan catabolic process [GO:0030214] GO:0004566; GO:0005102; GO:0005615; GO:0019391; GO:0019904; GO:0030200; GO:0030207; GO:0030214; GO:0030246; GO:0043202 35399 FUN_015084 183 57 45 235 188 ptg000009l:5947562-5958636 P56434 8.1e-45 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (EC 2.4.1.152) (Fucosyltransferase 6) (Fucosyltransferase VI) (Fuc-TVI) (FucT-VI) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; N-glycan fucosylation [GO:0036071]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0005576; GO:0005794; GO:0006487; GO:0006493; GO:0006688; GO:0017083; GO:0032580; GO:0036065; GO:0036071; GO:0046920 35400 FUN_015084 183 57 45 235 188 ptg000009l:5947562-5958636 P56434 1.3e-36 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (EC 2.4.1.152) (Fucosyltransferase 6) (Fucosyltransferase VI) (Fuc-TVI) (FucT-VI) (Galactoside 3-L-fucosyltransferase) Pan troglodytes (Chimpanzee) fucosylation [GO:0036065]; glycosphingolipid biosynthetic process [GO:0006688]; N-glycan fucosylation [GO:0036071]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493] GO:0005576; GO:0005794; GO:0006487; GO:0006493; GO:0006688; GO:0017083; GO:0032580; GO:0036065; GO:0036071; GO:0046920 35401 FUN_015085 33 10 19 23 14 ptg000009l:5964598-5965444 Q11126 2.44e-38 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 35402 FUN_036718 0 0 7 3 24 NA NA NA NA NA NA NA 35403 FUN_036717 0 0 0 0 6 NA NA NA NA NA NA NA 35404 FUN_036716 35 89 42 56 13 NA NA NA NA NA NA NA 35405 FUN_036710 0 0 1 0 9 NA NA NA NA NA NA NA 35406 FUN_036713 0 0 4 5 12 NA NA NA NA NA NA NA 35407 FUN_037442 6809 6347 3868 6969 5013 NA NA NA NA NA NA NA 35408 FUN_037443 872 953 536 1204 1026 NA NA NA NA NA NA NA 35409 FUN_037440 1094 873 621 1346 1392 NA NA NA NA NA NA NA 35410 FUN_037441 275 243 124 191 330 NA NA NA NA NA NA NA 35411 FUN_037446 95 17 16 132 102 NA NA NA NA NA NA NA 35412 FUN_037447 42881 58502 27388 42586 28828 ptg000026l:10641312-10644436 P62282 3.19e-33 40S ribosomal protein S11 Rattus norvegicus (Rat) osteoblast differentiation [GO:0001649]; translation [GO:0006412] GO:0001649; GO:0003735; GO:0006412; GO:0016020; GO:0019843; GO:0022626; GO:0022627; GO:0045202 35413 FUN_037444 2223 1937 1791 2874 3702 ptg000026l:10530726-10543554 Q7Z4S6 5.25e-30 Kinesin-like protein KIF21A (Kinesin-like protein KIF2) (Renal carcinoma antigen NY-REN-62) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0003777; GO:0005524; GO:0005829; GO:0005871; GO:0005874; GO:0005886; GO:0007018; GO:0008017; GO:0016887; GO:0030424; GO:0030425; GO:0071532 35414 FUN_037445 3434 2432 1502 3991 2385 NA NA NA NA NA NA NA 35415 FUN_037448 3110 2553 1819 2106 1348 NA NA NA NA NA NA NA 35416 FUN_037449 0 14 21 0 0 NA NA NA NA NA NA NA 35417 FUN_006129 1208 1368 261 1204 610 NA NA NA NA NA NA NA 35418 FUN_006125 0 101 0 97 52 NA NA NA NA NA NA NA 35419 FUN_006124 0 152 0 67 70 ptg000001l:8059126-8068268 P14381 2.66e-38 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 35420 FUN_006124 0 152 0 67 70 ptg000001l:8059126-8068268 P14381 2.66e-38 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 35421 FUN_006127 0 1201 188 791 918 ptg000001l:8105937-8115144 P35061 2.18e-37 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35422 FUN_006127 0 1201 188 791 918 ptg000001l:8105937-8115144 P35061 7.27e-37 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35423 FUN_006127 0 1201 188 791 918 ptg000001l:8105937-8115144 P35061 2.43e-24 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35424 FUN_006127 0 1201 188 791 918 ptg000001l:8105937-8115144 P35061 2.43e-24 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35425 FUN_006126 14 1110 7 861 1022 NA NA NA NA NA NA NA 35426 FUN_006121 0 0 105 0 0 NA NA NA NA NA NA NA 35427 FUN_006120 1037 731 526 794 1087 NA NA NA NA NA NA NA 35428 FUN_006123 133 40 66 0 94 NA NA NA NA NA NA NA 35429 FUN_031291 69 81 47 65 110 NA NA NA NA NA NA NA 35430 FUN_031290 238 148 100 224 433 ptg000023l:19012538-19039010 Q8BGE5 1.83e-38 Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) Mus musculus (Mouse) double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of protein monoubiquitination [GO:1902527]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000400; GO:0000712; GO:0000785; GO:0003682; GO:0003724; GO:0004518; GO:0005524; GO:0005654; GO:0009378; GO:0016887; GO:0031297; GO:0036297; GO:0043138; GO:0043240; GO:0045003; GO:0071821; GO:0071932; GO:1902527 35431 FUN_031290 238 148 100 224 433 ptg000023l:19012538-19039010 Q8BGE5 1.9e-38 Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) Mus musculus (Mouse) double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of protein monoubiquitination [GO:1902527]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000400; GO:0000712; GO:0000785; GO:0003682; GO:0003724; GO:0004518; GO:0005524; GO:0005654; GO:0009378; GO:0016887; GO:0031297; GO:0036297; GO:0043138; GO:0043240; GO:0045003; GO:0071821; GO:0071932; GO:1902527 35432 FUN_031290 238 148 100 224 433 ptg000023l:19012538-19039010 Q8BGE5 3.46e-24 Fanconi anemia group M protein homolog (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) Mus musculus (Mouse) double-strand break repair via synthesis-dependent strand annealing [GO:0045003]; interstrand cross-link repair [GO:0036297]; positive regulation of protein monoubiquitination [GO:1902527]; replication fork processing [GO:0031297]; replication fork reversal [GO:0071932]; resolution of meiotic recombination intermediates [GO:0000712] GO:0000400; GO:0000712; GO:0000785; GO:0003682; GO:0003724; GO:0004518; GO:0005524; GO:0005654; GO:0009378; GO:0016887; GO:0031297; GO:0036297; GO:0043138; GO:0043240; GO:0045003; GO:0071821; GO:0071932; GO:1902527 35433 FUN_031293 318 344 180 298 192 ptg000023l:19055875-19058228 Q8NBN7 2.36e-24 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 35434 FUN_031292 329 293 144 442 242 NA NA NA NA NA NA NA 35435 FUN_031295 229 48 97 177 66 ptg000023l:19064879-19069986 Q8CEE7 8.73e-46 Retinol dehydrogenase 13 (EC 1.1.1.300) Mus musculus (Mouse) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005739; GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 35436 FUN_031294 259 270 214 440 161 NA NA NA NA NA NA NA 35437 FUN_031297 10 24 0 63 0 NA NA NA NA NA NA NA 35438 FUN_031296 2927 2214 2000 3101 1563 ptg000023l:19072968-19083884 Q8CEE7 3.56e-44 Retinol dehydrogenase 13 (EC 1.1.1.300) Mus musculus (Mouse) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005739; GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 35439 FUN_031296 2927 2214 2000 3101 1563 ptg000023l:19072968-19083884 Q8CEE7 3.81e-44 Retinol dehydrogenase 13 (EC 1.1.1.300) Mus musculus (Mouse) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005739; GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 35440 FUN_031299 26 0 0 35 14 NA NA NA NA NA NA NA 35441 FUN_031298 34 27 49 52 34 ptg000023l:19090626-19091181 Q9W0Y8 8.16e-73 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 35442 FUN_037194 221 336 81 264 182 ptg000026l:6875671-6889001 Q76KP1 1.71e-25 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 35443 FUN_037195 32 17 9 38 38 NA NA NA NA NA NA NA 35444 FUN_037196 1672 923 922 1508 1016 NA NA NA NA NA NA NA 35445 FUN_037197 8760 4346 3711 7590 4976 ptg000026l:6939106-6952961 A6H742 8.85e-22 Plastin-1 Bos taurus (Bovine) actin filament bundle assembly [GO:0051017]; actin filament network formation [GO:0051639]; auditory receptor cell stereocilium organization [GO:0060088]; intestinal D-glucose absorption [GO:0001951]; positive regulation of multicellular organism growth [GO:0040018]; positive regulation of protein localization to plasma membrane [GO:1903078]; regulation of microvillus length [GO:0032532]; terminal web assembly [GO:1902896]; vestibular receptor cell stereocilium organization [GO:0060121] GO:0001951; GO:0005509; GO:0005737; GO:0005884; GO:0005903; GO:0032420; GO:0032432; GO:0032532; GO:0040018; GO:0051015; GO:0051017; GO:0051639; GO:0060088; GO:0060121; GO:1902896; GO:1903078; GO:1990357 35446 FUN_037190 0 0 0 27 61 ptg000026l:6844584-6846200 Q76KP1 8e-30 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 35447 FUN_037191 26 13 94 80 129 NA NA NA NA NA NA NA 35448 FUN_037192 550 387 396 633 673 ptg000026l:6861688-6872600 Q76KP1 1.6e-24 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 35449 FUN_037193 1 25 36 62 46 NA NA NA NA NA NA NA 35450 FUN_037198 68 67 113 35 42 ptg000026l:6957937-6960313 Q8C0R9 9.61e-35 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 35451 FUN_037198 68 67 113 35 42 ptg000026l:6957937-6960313 Q8C0R9 3e-34 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 35452 FUN_037198 68 67 113 35 42 ptg000026l:6957937-6960313 Q8C0R9 7.71e-29 Leucine-rich repeat and death domain-containing protein 1 Mus musculus (Mouse) positive regulation of Ras protein signal transduction [GO:0046579]; signal transduction [GO:0007165] GO:0007165; GO:0046579 35453 FUN_037199 3853 2717 1908 5575 3956 NA NA NA NA NA NA NA 35454 FUN_006697 0 17 23 81 72 NA NA NA NA NA NA NA 35455 FUN_006696 1447 1163 391 2504 1025 NA NA NA NA NA NA NA 35456 FUN_006695 2711 2305 524 4152 2614 NA NA NA NA NA NA NA 35457 FUN_006694 1047 362 583 813 1044 NA NA NA NA NA NA NA 35458 FUN_006693 1150 464 440 1088 664 NA NA NA NA NA NA NA 35459 FUN_006692 8014 661 1790 3291 1847 NA NA NA NA NA NA NA 35460 FUN_006691 1845 15 1658 3190 1277 NA NA NA NA NA NA NA 35461 FUN_006690 3138 41 943 2676 429 ptg000001l:15611453-15632401 P21328 3.2e-44 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 35462 FUN_006699 122 0 0 0 380 NA NA NA NA NA NA NA 35463 FUN_006698 22 18 0 0 28 NA NA NA NA NA NA NA 35464 FUN_042819 90 0 12 37 0 NA NA NA NA NA NA NA 35465 FUN_005760 6 14 34 13 186 NA NA NA NA NA NA NA 35466 FUN_001472 14013 10193 5482 8458 6449 NA NA NA NA NA NA NA 35467 FUN_001473 1267 697 656 804 790 NA NA NA NA NA NA NA 35468 FUN_001470 96 339 183 296 160 NA NA NA NA NA NA NA 35469 FUN_001471 749 65 626 0 0 NA NA NA NA NA NA NA 35470 FUN_001476 367 173 199 398 519 NA NA NA NA NA NA NA 35471 FUN_001477 2128 662 1046 959 674 NA NA NA NA NA NA NA 35472 FUN_001474 847 450 283 504 521 NA NA NA NA NA NA NA 35473 FUN_001478 937 337 482 429 436 NA NA NA NA NA NA NA 35474 FUN_001479 605 122 297 312 240 NA NA NA NA NA NA NA 35475 FUN_033638 0 0 1 0 6 NA NA NA NA NA NA NA 35476 FUN_033631 0 0 0 0 18 NA NA NA NA NA NA NA 35477 FUN_033632 20 87 7 57 33 NA NA NA NA NA NA NA 35478 FUN_009125 216 380 73 31 4 NA NA NA NA NA NA NA 35479 FUN_026701 0 19 0 12 0 NA NA NA NA NA NA NA 35480 FUN_037479 927 568 484 1273 614 ptg000026l:10922691-10943927 P53461 8.03e-34 Actin, nonmuscle (EC 3.6.4.-) [Cleaved into: Actin, nonmuscle, intermediate form] Halocynthia roretzi (Sea squirt) (Cynthia roretzi) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 35481 FUN_030613 0 0 0 0 36 NA NA NA NA NA NA NA 35482 FUN_023099 423 223 109 247 301 NA NA NA NA NA NA NA 35483 FUN_010975 0 8 0 1 0 NA NA NA NA NA NA NA 35484 FUN_010974 4765 6704 1885 2672 2499 ptg000007l:5110855-5120527 A7RM20 1.7e-27 Eukaryotic translation initiation factor 3 subunit I (eIF3i) Nematostella vectensis (Starlet sea anemone) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0002183; GO:0003723; GO:0003743; GO:0016282; GO:0033290; GO:0071541 35485 FUN_010974 4765 6704 1885 2672 2499 ptg000007l:5110855-5120527 A7RM20 1.72e-22 Eukaryotic translation initiation factor 3 subunit I (eIF3i) Nematostella vectensis (Starlet sea anemone) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0002183; GO:0003723; GO:0003743; GO:0016282; GO:0033290; GO:0071541 35486 FUN_010974 4765 6704 1885 2672 2499 ptg000007l:5110855-5120527 A7RM20 5.18e-21 Eukaryotic translation initiation factor 3 subunit I (eIF3i) Nematostella vectensis (Starlet sea anemone) cytoplasmic translational initiation [GO:0002183]; formation of cytoplasmic translation initiation complex [GO:0001732] GO:0001732; GO:0002183; GO:0003723; GO:0003743; GO:0016282; GO:0033290; GO:0071541 35487 FUN_010977 1344 543 507 1838 864 NA NA NA NA NA NA NA 35488 FUN_031909 1430 579 652 928 824 NA NA NA NA NA NA NA 35489 FUN_031908 123 48 59 159 90 NA NA NA NA NA NA NA 35490 FUN_010976 1659 3064 434 690 985 NA NA NA NA NA NA NA 35491 FUN_031901 1722 662 1018 1291 1850 NA NA NA NA NA NA NA 35492 FUN_031900 1237 283 420 190 1062 ptg000023l:26604966-26606331 Q00168 3.14e-39 Calcium/calmodulin-dependent protein kinase type II alpha chain (CaM-kinase II alpha chain) (EC 2.7.11.17) Drosophila melanogaster (Fruit fly) cellular response to starvation [GO:0009267]; chemical synaptic transmission [GO:0007268]; courtship behavior [GO:0007619]; learning or memory [GO:0007611]; long-term memory [GO:0007616]; male courtship behavior [GO:0008049]; negative regulation of cytokine production [GO:0001818]; negative regulation of lipid storage [GO:0010888]; neuromuscular junction development [GO:0007528]; peptidyl-threonine autophosphorylation [GO:1990443]; positive regulation of synaptic transmission, dopaminergic [GO:0032226]; protein phosphorylation [GO:0006468]; regulation of filopodium assembly [GO:0051489]; regulation of ovulation [GO:0060278]; regulation of synaptic assembly at neuromuscular junction [GO:0008582] GO:0001818; GO:0004674; GO:0004683; GO:0005516; GO:0005524; GO:0005737; GO:0006468; GO:0007268; GO:0007528; GO:0007611; GO:0007616; GO:0007619; GO:0008049; GO:0008582; GO:0009267; GO:0010888; GO:0030424; GO:0030425; GO:0032226; GO:0043005; GO:0045211; GO:0048786; GO:0051489; GO:0060278; GO:0106310; GO:1990443 35493 FUN_031903 2098 1698 2657 2442 2119 ptg000023l:26643918-26651750 Q54N49 9.1e-29 Inositol-3-phosphate synthase (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (IPS) (MI-1-P synthase) (MIP synthase) Dictyostelium discoideum (Social amoeba) autophagy [GO:0006914]; cell-substrate adhesion [GO:0031589]; inositol biosynthetic process [GO:0006021]; mitotic cytokinesis [GO:0000281]; phospholipid biosynthetic process [GO:0008654]; regulation of phospholipid metabolic process [GO:1903725] GO:0000281; GO:0004512; GO:0005737; GO:0005829; GO:0006021; GO:0006914; GO:0008654; GO:0031589; GO:1903725 35494 FUN_031903 2098 1698 2657 2442 2119 ptg000023l:26643918-26651750 Q54N49 7.76e-26 Inositol-3-phosphate synthase (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (IPS) (MI-1-P synthase) (MIP synthase) Dictyostelium discoideum (Social amoeba) autophagy [GO:0006914]; cell-substrate adhesion [GO:0031589]; inositol biosynthetic process [GO:0006021]; mitotic cytokinesis [GO:0000281]; phospholipid biosynthetic process [GO:0008654]; regulation of phospholipid metabolic process [GO:1903725] GO:0000281; GO:0004512; GO:0005737; GO:0005829; GO:0006021; GO:0006914; GO:0008654; GO:0031589; GO:1903725 35495 FUN_031902 440 361 541 1408 967 NA NA NA NA NA NA NA 35496 FUN_031904 1928 771 706 3381 2011 NA NA NA NA NA NA NA 35497 FUN_031907 434 232 228 360 450 NA NA NA NA NA NA NA 35498 FUN_031906 0 0 72 0 61 NA NA NA NA NA NA NA 35499 FUN_034363 1649 1043 817 1182 1548 NA NA NA NA NA NA NA 35500 FUN_034366 1096 1141 579 1255 1181 NA NA NA NA NA NA NA 35501 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 2.15e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35502 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 5.55e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35503 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 8.19e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35504 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 7.56e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35505 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.4e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35506 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 4.42e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35507 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 2.39e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35508 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 2.39e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35509 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 7.47e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35510 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 5.23e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35511 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.81e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35512 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.99e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35513 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 2.8e-129 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35514 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 2.66e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35515 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 3.47e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35516 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 9.11e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35517 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.25e-124 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35518 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.99e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35519 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 6.83e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35520 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.49e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35521 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.26e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35522 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 8.68e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35523 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.3e-34 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35524 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.52e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35525 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.82e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35526 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 6.11e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35527 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 8.4e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35528 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 7.33e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35529 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 1.05e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35530 FUN_018376 734 239 94 356 204 ptg000012l:8649063-8658841 Q96AY4 6.68e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35531 FUN_018374 2503 43 954 262 1743 NA NA NA NA NA NA NA 35532 FUN_034368 933 520 258 768 700 NA NA NA NA NA NA NA 35533 FUN_018378 68 96 12 0 66 NA NA NA NA NA NA NA 35534 FUN_006909 124 300 49 0 59 NA NA NA NA NA NA NA 35535 FUN_006908 238 81 70 48 116 NA NA NA NA NA NA NA 35536 FUN_006907 177 62 86 21 176 NA NA NA NA NA NA NA 35537 FUN_006906 3618 544 4930 1794 5835 NA NA NA NA NA NA NA 35538 FUN_006905 6 0 44 11 15 NA NA NA NA NA NA NA 35539 FUN_006904 267 502 491 120 168 NA NA NA NA NA NA NA 35540 FUN_006903 63 40 39 107 67 NA NA NA NA NA NA NA 35541 FUN_006902 194 131 61 193 61 NA NA NA NA NA NA NA 35542 FUN_006901 920 759 485 649 479 NA NA NA NA NA NA NA 35543 FUN_006900 81 393 112 0 87 NA NA NA NA NA NA NA 35544 FUN_014720 139 131 108 145 213 NA NA NA NA NA NA NA 35545 FUN_012345 12 19 0 0 0 NA NA NA NA NA NA NA 35546 FUN_035105 1472 579 374 899 389 NA NA NA NA NA NA NA 35547 FUN_035104 2077 1178 269 233 324 NA NA NA NA NA NA NA 35548 FUN_035107 640 266 199 256 159 NA NA NA NA NA NA NA 35549 FUN_035106 93 31 9 32 0 NA NA NA NA NA NA NA 35550 FUN_035101 1439 970 187 173 65 NA NA NA NA NA NA NA 35551 FUN_035100 0 13 14 0 0 NA NA NA NA NA NA NA 35552 FUN_035103 2479 1543 886 740 996 NA NA NA NA NA NA NA 35553 FUN_041433 219 277 242 404 422 NA NA NA NA NA NA NA 35554 FUN_035109 1737 796 35 33 4 NA NA NA NA NA NA NA 35555 FUN_035108 165 106 0 0 0 NA NA NA NA NA NA NA 35556 FUN_000202 2199 1818 1308 1552 1528 NA NA NA NA NA NA NA 35557 FUN_000203 3123 2415 1322 1882 2186 NA NA NA NA NA NA NA 35558 FUN_007058 0 8 0 7 15 NA NA NA NA NA NA NA 35559 FUN_007059 107 99 70 137 172 NA NA NA NA NA NA NA 35560 FUN_041434 439 191 167 414 905 NA NA NA NA NA NA NA 35561 FUN_007052 0 42 41 33 94 NA NA NA NA NA NA NA 35562 FUN_007053 1748 1196 689 1170 747 ptg000001l:19883949-19885429 Q8VDL9 4.95e-66 Zinc finger protein GLIS2 (GLI-similar 2) (Neuronal Krueppel-like protein) (Zinc finger protein GLI5) Mus musculus (Mouse) cell differentiation involved in kidney development [GO:0061005]; central nervous system development [GO:0007417]; hematopoietic stem cell homeostasis [GO:0061484]; kidney development [GO:0001822]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of smoothened signaling pathway [GO:0045879]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000976; GO:0000977; GO:0000978; GO:0000981; GO:0001228; GO:0001822; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005667; GO:0005737; GO:0006357; GO:0007417; GO:0016607; GO:0043433; GO:0045879; GO:0045892; GO:0045893; GO:0045944; GO:0046872; GO:0061005; GO:0061484; GO:0097730; GO:1900182; GO:1990837 35563 FUN_007050 844 807 266 882 282 NA NA NA NA NA NA NA 35564 FUN_007051 88 52 31 185 31 NA NA NA NA NA NA NA 35565 FUN_007056 868 771 354 548 509 NA NA NA NA NA NA NA 35566 FUN_007057 539 247 391 445 834 NA NA NA NA NA NA NA 35567 FUN_007054 757 339 190 288 320 ptg000001l:19889950-19890954 Q01664 2.75e-23 Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41) Homo sapiens (Human) cellular response to dexamethasone stimulus [GO:0071549]; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [GO:0006978]; negative regulation by host of viral transcription [GO:0043922]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045736]; negative regulation of DNA binding [GO:0043392]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of gene expression [GO:0010629]; positive regulation by host of viral transcription [GO:0043923]; positive regulation of apoptotic process [GO:0043065]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO:2001269]; positive regulation of DNA-templated transcription [GO:0045893]; protein-containing complex assembly [GO:0065003]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000785; GO:0000976; GO:0000978; GO:0000981; GO:0001228; GO:0003677; GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0006978; GO:0008285; GO:0010629; GO:0017053; GO:0042803; GO:0042826; GO:0043065; GO:0043392; GO:0043565; GO:0043922; GO:0043923; GO:0045736; GO:0045892; GO:0045893; GO:0065003; GO:0070888; GO:0071549; GO:1901990; GO:1990837; GO:2001269 35568 FUN_007055 4536 3417 2045 3850 3158 ptg000001l:19892863-19910887 Q90YM8 4.24e-32 Cytoplasmic FMR1-interacting protein 1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; modification of synaptic structure [GO:0099563]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of translation [GO:0006417]; ruffle organization [GO:0031529] GO:0000340; GO:0000902; GO:0001726; GO:0005737; GO:0006417; GO:0007411; GO:0008360; GO:0030027; GO:0030031; GO:0030032; GO:0030833; GO:0031209; GO:0031267; GO:0031529; GO:0043005; GO:0045202; GO:0048471; GO:0048675; GO:0051015; GO:0099563 35569 FUN_007055 4536 3417 2045 3850 3158 ptg000001l:19892863-19910887 Q90YM8 1.11e-24 Cytoplasmic FMR1-interacting protein 1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; modification of synaptic structure [GO:0099563]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of translation [GO:0006417]; ruffle organization [GO:0031529] GO:0000340; GO:0000902; GO:0001726; GO:0005737; GO:0006417; GO:0007411; GO:0008360; GO:0030027; GO:0030031; GO:0030032; GO:0030833; GO:0031209; GO:0031267; GO:0031529; GO:0043005; GO:0045202; GO:0048471; GO:0048675; GO:0051015; GO:0099563 35570 FUN_007055 4536 3417 2045 3850 3158 ptg000001l:19892863-19910887 Q90YM8 9.41e-22 Cytoplasmic FMR1-interacting protein 1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; modification of synaptic structure [GO:0099563]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of translation [GO:0006417]; ruffle organization [GO:0031529] GO:0000340; GO:0000902; GO:0001726; GO:0005737; GO:0006417; GO:0007411; GO:0008360; GO:0030027; GO:0030031; GO:0030032; GO:0030833; GO:0031209; GO:0031267; GO:0031529; GO:0043005; GO:0045202; GO:0048471; GO:0048675; GO:0051015; GO:0099563 35571 FUN_007055 4536 3417 2045 3850 3158 ptg000001l:19892863-19910887 Q90YM8 1.17e-21 Cytoplasmic FMR1-interacting protein 1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) axon extension [GO:0048675]; axon guidance [GO:0007411]; cell morphogenesis [GO:0000902]; cell projection assembly [GO:0030031]; lamellipodium assembly [GO:0030032]; modification of synaptic structure [GO:0099563]; regulation of actin filament polymerization [GO:0030833]; regulation of cell shape [GO:0008360]; regulation of translation [GO:0006417]; ruffle organization [GO:0031529] GO:0000340; GO:0000902; GO:0001726; GO:0005737; GO:0006417; GO:0007411; GO:0008360; GO:0030027; GO:0030031; GO:0030032; GO:0030833; GO:0031209; GO:0031267; GO:0031529; GO:0043005; GO:0045202; GO:0048471; GO:0048675; GO:0051015; GO:0099563 35572 FUN_043254 850 464 745 530 526 NA NA NA NA NA NA NA 35573 FUN_043255 14 5 0 33 0 NA NA NA NA NA NA NA 35574 FUN_043250 1651 1494 1025 1745 1902 ptg000047l:5934907-5939310 Q9PUB8 1.13e-28 Zinc transporter Slc39a7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) Danio rerio (Zebrafish) (Brachydanio rerio) cellular zinc ion homeostasis [GO:0006882]; zinc ion homeostasis [GO:0055069]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0005385; GO:0005789; GO:0005794; GO:0006829; GO:0006882; GO:0055069; GO:0071577 35575 FUN_043250 1651 1494 1025 1745 1902 ptg000047l:5934907-5939310 Q9PUB8 1.48e-21 Zinc transporter Slc39a7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) Danio rerio (Zebrafish) (Brachydanio rerio) cellular zinc ion homeostasis [GO:0006882]; zinc ion homeostasis [GO:0055069]; zinc ion transmembrane transport [GO:0071577]; zinc ion transport [GO:0006829] GO:0005385; GO:0005789; GO:0005794; GO:0006829; GO:0006882; GO:0055069; GO:0071577 35576 FUN_043251 1435 1114 569 1295 1136 NA NA NA NA NA NA NA 35577 FUN_043252 889 383 428 535 677 ptg000047l:5952634-5970028 Q9Y6A1 8.12e-23 Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1) Homo sapiens (Human) extracellular matrix organization [GO:0030198]; positive regulation of protein O-linked glycosylation [GO:1904100]; protein O-linked glycosylation [GO:0006493]; protein O-linked mannosylation [GO:0035269] GO:0000030; GO:0001669; GO:0004169; GO:0005783; GO:0005789; GO:0006493; GO:0016020; GO:0016529; GO:0030198; GO:0035269; GO:0046872; GO:1904100 35578 FUN_043253 267 205 134 266 288 ptg000047l:5973036-5975806 Q9Z321 0 DNA topoisomerase 3-beta-1 (EC 5.6.2.1) (DNA topoisomerase III beta-1) Mus musculus (Mouse) chromosome segregation [GO:0007059]; DNA topological change [GO:0006265] GO:0000793; GO:0003677; GO:0003916; GO:0003917; GO:0005634; GO:0006265; GO:0007059; GO:0140225 35579 FUN_043258 1973 1232 835 1953 1632 ptg000047l:5994990-6021613 P81274 1.84e-60 G-protein-signaling modulator 2 (Mosaic protein LGN) Homo sapiens (Human) cell division [GO:0051301]; establishment of mitotic spindle orientation [GO:0000132]; G protein-coupled receptor signaling pathway [GO:0007186]; maintenance of centrosome location [GO:0051661]; mitotic spindle organization [GO:0007052]; positive regulation of protein localization to cell cortex [GO:1904778]; positive regulation of spindle assembly [GO:1905832]; Ran protein signal transduction [GO:0031291]; regulation of mitotic spindle organization [GO:0060236] GO:0000132; GO:0000166; GO:0001965; GO:0005092; GO:0005737; GO:0005813; GO:0005829; GO:0005938; GO:0007052; GO:0007186; GO:0008022; GO:0016328; GO:0019904; GO:0031291; GO:0032991; GO:0042802; GO:0043621; GO:0051301; GO:0051661; GO:0060236; GO:0070840; GO:0097431; GO:0097575; GO:0099738; GO:1904778; GO:1905832 35580 FUN_043259 2790 1931 1799 3772 2038 ptg000047l:6027893-6069092 Q5VT06 1.41e-25 Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa) Homo sapiens (Human) microtubule anchoring [GO:0034453]; non-motile cilium assembly [GO:1905515]; protein localization to centrosome [GO:0071539] GO:0005634; GO:0005737; GO:0005813; GO:0005814; GO:0005819; GO:0008017; GO:0016020; GO:0034453; GO:0042995; GO:0071539; GO:1905515 35581 FUN_014427 3 8 78 35 282 NA NA NA NA NA NA NA 35582 FUN_041439 76 99 79 58 48 NA NA NA NA NA NA NA 35583 FUN_013028 0 61 14 2 0 NA NA NA NA NA NA NA 35584 FUN_013430 0 82 39 0 31 NA NA NA NA NA NA NA 35585 FUN_013026 5 13 3 0 26 NA NA NA NA NA NA NA 35586 FUN_033028 0 0 26 54 9 NA NA NA NA NA NA NA 35587 FUN_013024 624 560 326 375 317 NA NA NA NA NA NA NA 35588 FUN_013022 2129 1025 1063 1555 1051 ptg000008l:18601547-18618749 Q5FWS6 1.09e-39 Kazrin Rattus norvegicus (Rat) keratinization [GO:0031424] GO:0001533; GO:0005829; GO:0005856; GO:0016607; GO:0030057; GO:0031424 35589 FUN_013022 2129 1025 1063 1555 1051 ptg000008l:18601547-18618749 Q5FWS6 3.57e-21 Kazrin Rattus norvegicus (Rat) keratinization [GO:0031424] GO:0001533; GO:0005829; GO:0005856; GO:0016607; GO:0030057; GO:0031424 35590 FUN_013023 8105 7843 4052 6649 3675 NA NA NA NA NA NA NA 35591 FUN_014424 2 2 8 7 15 NA NA NA NA NA NA NA 35592 FUN_013435 0 682 241 89 0 ptg000008l:22405048-22407171 Q8VD65 2.22e-22 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) Mus musculus (Mouse) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016236; GO:0016241; GO:0030242; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 35593 FUN_014422 0 2 7 6 12 NA NA NA NA NA NA NA 35594 FUN_013439 122 159 22 74 52 NA NA NA NA NA NA NA 35595 FUN_041090 0 0 12 0 0 NA NA NA NA NA NA NA 35596 FUN_041097 0 0 7 0 0 NA NA NA NA NA NA NA 35597 FUN_039838 303 208 176 143 52 NA NA NA NA NA NA NA 35598 FUN_036450 13 53 13 0 6 NA NA NA NA NA NA NA 35599 FUN_036456 14 0 0 0 0 NA NA NA NA NA NA NA 35600 FUN_036454 0 0 0 26 0 NA NA NA NA NA NA NA 35601 FUN_039871 442 618 193 384 260 NA NA NA NA NA NA NA 35602 FUN_002109 3 0 44 0 36 NA NA NA NA NA NA NA 35603 FUN_039870 828 1009 418 1105 1390 NA NA NA NA NA NA NA 35604 FUN_002103 6454 5341 2000 4978 3709 NA NA NA NA NA NA NA 35605 FUN_002102 24107 12860 10736 18145 18196 ntLink_6:19821361-19836842 P07949 3.37e-21 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 35606 FUN_002102 24107 12860 10736 18145 18196 ntLink_6:19821361-19836842 P07949 3.37e-21 Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment] Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; axon guidance [GO:0007411]; cellular response to retinoic acid [GO:0071300]; embryonic epithelial tube formation [GO:0001838]; enteric nervous system development [GO:0048484]; glial cell-derived neurotrophic factor receptor signaling pathway [GO:0035860]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; innervation [GO:0060384]; lymphocyte migration into lymphoid organs [GO:0097021]; MAPK cascade [GO:0000165]; membrane protein proteolysis [GO:0033619]; neural crest cell migration [GO:0001755]; neuron cell-cell adhesion [GO:0007158]; neuron maturation [GO:0042551]; Peyer's patch morphogenesis [GO:0061146]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell migration [GO:0030335]; positive regulation of cell size [GO:0045793]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001241]; positive regulation of gene expression [GO:0010628]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of metanephric glomerulus development [GO:0072300]; positive regulation of neuron maturation [GO:0014042]; positive regulation of neuron projection development [GO:0010976]; positive regulation of peptidyl-serine phosphorylation of STAT protein [GO:0033141]; positive regulation of protein kinase B signaling [GO:0051897]; posterior midgut development [GO:0007497]; protein phosphorylation [GO:0006468]; regulation of axonogenesis [GO:0050770]; regulation of cell adhesion [GO:0030155]; response to pain [GO:0048265]; response to xenobiotic stimulus [GO:0009410]; retina development in camera-type eye [GO:0060041]; signal transduction [GO:0007165]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; ureter maturation [GO:0035799]; ureteric bud development [GO:0001657] GO:0000165; GO:0001657; GO:0001755; GO:0001838; GO:0004713; GO:0004714; GO:0005509; GO:0005524; GO:0005769; GO:0005886; GO:0006468; GO:0006919; GO:0007156; GO:0007158; GO:0007165; GO:0007169; GO:0007411; GO:0007497; GO:0009410; GO:0010008; GO:0010628; GO:0010976; GO:0014042; GO:0030155; GO:0030335; GO:0030424; GO:0030425; GO:0033141; GO:0033619; GO:0033630; GO:0033674; GO:0035799; GO:0035860; GO:0038023; GO:0042551; GO:0043025; GO:0043235; GO:0043410; GO:0045121; GO:0045793; GO:0045893; GO:0048265; GO:0048484; GO:0050770; GO:0051897; GO:0060041; GO:0060384; GO:0061146; GO:0071300; GO:0072300; GO:0097021; GO:0098797; GO:2001241 35607 FUN_002101 0 0 0 7 4 NA NA NA NA NA NA NA 35608 FUN_002100 0 0 0 0 26 ntLink_6:19791809-19796135 P22607 9.77e-28 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 35609 FUN_002100 0 0 0 0 26 ntLink_6:19791809-19796135 P22607 9.77e-28 Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333) Homo sapiens (Human) bone maturation [GO:0070977]; bone mineralization [GO:0030282]; bone morphogenesis [GO:0060349]; cell-cell signaling [GO:0007267]; chondrocyte differentiation [GO:0002062]; chondrocyte proliferation [GO:0035988]; endochondral bone growth [GO:0003416]; endochondral ossification [GO:0001958]; fibroblast growth factor receptor apoptotic signaling pathway [GO:1902178]; fibroblast growth factor receptor signaling pathway [GO:0008543]; MAPK cascade [GO:0000165]; negative regulation of developmental growth [GO:0048640]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of kinase activity [GO:0033674]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phospholipase activity [GO:0010518]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; skeletal system development [GO:0001501]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0000165; GO:0001501; GO:0001958; GO:0002062; GO:0003416; GO:0004713; GO:0004714; GO:0005007; GO:0005524; GO:0005576; GO:0005634; GO:0005783; GO:0005794; GO:0005886; GO:0007169; GO:0007267; GO:0008284; GO:0008543; GO:0009986; GO:0010518; GO:0017134; GO:0018108; GO:0030133; GO:0030282; GO:0033674; GO:0035988; GO:0042531; GO:0042802; GO:0043235; GO:0043410; GO:0043552; GO:0046777; GO:0048640; GO:0060349; GO:0070374; GO:0070977; GO:1902178 35610 FUN_002107 0 0 0 0 17 NA NA NA NA NA NA NA 35611 FUN_002106 114 80 77 116 204 NA NA NA NA NA NA NA 35612 FUN_002105 707 939 391 962 833 ntLink_6:19933497-20075082 Q95SX7 2.53e-32 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 35613 FUN_002104 0 0 0 13 17 NA NA NA NA NA NA NA 35614 FUN_039872 44 30 7 152 95 ptg000031l:1138612-1141143 Q9ULM3 1.99e-64 YEATS domain-containing protein 2 Homo sapiens (Human) chromatin remodeling [GO:0006338]; histone acetylation [GO:0016573]; histone H3 acetylation [GO:0043966]; histone H3-K14 acetylation [GO:0044154]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of cell cycle [GO:0051726]; regulation of cell division [GO:0051302]; regulation of DNA-templated transcription [GO:0006355]; regulation of embryonic development [GO:0045995]; regulation of histone deacetylation [GO:0031063]; regulation of transcription by RNA polymerase II [GO:0006357]; regulation of tubulin deacetylation [GO:0090043] GO:0000122; GO:0005634; GO:0006338; GO:0006355; GO:0006357; GO:0016573; GO:0017025; GO:0031063; GO:0035267; GO:0042393; GO:0043966; GO:0044154; GO:0045892; GO:0045995; GO:0051302; GO:0051726; GO:0072686; GO:0090043; GO:0140030; GO:0140672 35615 FUN_033811 8 0 18 0 43 NA NA NA NA NA NA NA 35616 FUN_039874 1465 2018 1138 1123 709 NA NA NA NA NA NA NA 35617 FUN_039877 12162 9166 8164 9139 4465 NA NA NA NA NA NA NA 35618 FUN_039876 1648 1262 672 1026 1145 ptg000031l:1201453-1215445 Q26626 2e-23 Kinesin-associated protein 3 (SpKAP115) Strongylocentrotus purpuratus (Purple sea urchin) cilium organization [GO:0044782]; microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] GO:0005930; GO:0007017; GO:0007018; GO:0016939; GO:0019894; GO:0035869; GO:0044782 35619 FUN_018912 14 2 13 77 16 NA NA NA NA NA NA NA 35620 FUN_039754 0 0 17 77 4 NA NA NA NA NA NA NA 35621 FUN_023601 121 96 39 64 110 ptg000017l:9752701-9758622 Q96AY4 1.29e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35622 FUN_023601 121 96 39 64 110 ptg000017l:9752701-9758622 Q96AY4 5.2e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35623 FUN_023601 121 96 39 64 110 ptg000017l:9752701-9758622 Q96AY4 1.61e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35624 FUN_023601 121 96 39 64 110 ptg000017l:9752701-9758622 Q96AY4 3.08e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35625 FUN_007098 587 429 517 419 510 NA NA NA NA NA NA NA 35626 FUN_018914 454 312 166 372 362 NA NA NA NA NA NA NA 35627 FUN_039751 0 0 0 0 13 NA NA NA NA NA NA NA 35628 FUN_007230 0 0 0 12 0 NA NA NA NA NA NA NA 35629 FUN_042619 1977 1252 926 2740 1730 NA NA NA NA NA NA NA 35630 FUN_042618 8174 2775 1279 3743 4469 ptg000039l:411557-422380 Q6P8U6 1.67e-36 Pancreatic triacylglycerol lipase (PL) (PTL) (Pancreatic lipase) (EC 3.1.1.3) Mus musculus (Mouse) intestinal cholesterol absorption [GO:0030299]; lipid catabolic process [GO:0016042]; lipid metabolic process [GO:0006629]; positive regulation of triglyceride lipase activity [GO:0061365]; post-embryonic development [GO:0009791] GO:0004806; GO:0005615; GO:0006629; GO:0009791; GO:0016042; GO:0016298; GO:0030299; GO:0046872; GO:0047376; GO:0061365 35631 FUN_042616 57 0 0 0 0 NA NA NA NA NA NA NA 35632 FUN_039753 27 3 15 99 57 ptg000030l:3312236-3315629 Q95SX7 1.97e-24 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 35633 FUN_042613 1341 2289 1467 1477 1178 NA NA NA NA NA NA NA 35634 FUN_042612 2510 772 1179 1275 1622 NA NA NA NA NA NA NA 35635 FUN_042611 0 36 17 27 62 NA NA NA NA NA NA NA 35636 FUN_042610 3098 2432 2195 3639 3747 ptg000039l:304686-330516 P20825 2.32e-90 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 35637 FUN_000938 0 0 0 55 30 NA NA NA NA NA NA NA 35638 FUN_007095 64 0 57 53 82 NA NA NA NA NA NA NA 35639 FUN_000939 0 35 0 11 28 NA NA NA NA NA NA NA 35640 FUN_031017 0 0 0 0 28 NA NA NA NA NA NA NA 35641 FUN_012856 24 7 11 0 0 NA NA NA NA NA NA NA 35642 FUN_012857 22 9 0 0 16 NA NA NA NA NA NA NA 35643 FUN_012853 0 3 2 82 0 NA NA NA NA NA NA NA 35644 FUN_012858 115 39 0 0 57 NA NA NA NA NA NA NA 35645 FUN_012859 50 17 0 0 16 NA NA NA NA NA NA NA 35646 FUN_011499 177 34 82 51 87 NA NA NA NA NA NA NA 35647 FUN_011498 0 0 0 69 7 NA NA NA NA NA NA NA 35648 FUN_002819 0 0 8 75 4 NA NA NA NA NA NA NA 35649 FUN_002818 17 5 33 0 72 NA NA NA NA NA NA NA 35650 FUN_008120 806 597 414 992 560 NA NA NA NA NA NA NA 35651 FUN_009849 685 596 112 290 107 ptg000004l:12524138-12527318 P55024 4.94e-115 Tyrosinase (EC 1.14.18.1) (Monophenol monooxygenase) Gallus gallus (Chicken) melanin biosynthetic process [GO:0042438]; response to blue light [GO:0009637] GO:0004503; GO:0009637; GO:0033162; GO:0042438; GO:0042470; GO:0046872 35652 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 4.84e-48 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35653 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 4.74e-41 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35654 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 4.74e-41 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35655 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 9.33e-40 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35656 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 4.81e-38 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35657 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 5.13e-35 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35658 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 6.21e-34 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35659 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.06e-33 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35660 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 2.33e-31 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35661 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 8.31e-31 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35662 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 2.4e-29 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35663 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.09e-28 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35664 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.15e-28 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35665 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.35e-27 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35666 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 6.37e-26 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35667 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.91e-25 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35668 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 8.1e-23 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35669 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.16e-21 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35670 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 1.7e-21 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35671 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 3.71e-21 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35672 FUN_002810 2327 651 717 1854 642 ntLink_8:6468108-6502316 Q9V5N8 3.8e-21 Protocadherin-like wing polarity protein stan (Protein flamingo) (Protein starry night) Drosophila melanogaster (Fruit fly) axon guidance [GO:0007411]; axonogenesis [GO:0007409]; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0016339]; cell surface receptor signaling pathway [GO:0007166]; cell-cell adhesion [GO:0098609]; dendrite development [GO:0016358]; dendrite morphogenesis [GO:0048813]; dendrite self-avoidance [GO:0070593]; establishment of imaginal disc-derived wing hair orientation [GO:0001737]; establishment of ommatidial planar polarity [GO:0042067]; establishment of planar polarity [GO:0001736]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; morphogenesis of a polarized epithelium [GO:0001738]; mushroom body development [GO:0016319]; ommatidial rotation [GO:0016318]; positive regulation of axon extension [GO:0045773]; positive regulation of axon guidance [GO:1902669]; R3/R4 development [GO:0048057]; regulation of axonogenesis [GO:0050770]; regulation of synapse assembly [GO:0051963]; regulation of tube length, open tracheal system [GO:0035159]; segment polarity determination [GO:0007367] GO:0001736; GO:0001737; GO:0001738; GO:0004888; GO:0004930; GO:0005509; GO:0005886; GO:0005911; GO:0007156; GO:0007166; GO:0007367; GO:0007409; GO:0007411; GO:0016020; GO:0016318; GO:0016319; GO:0016324; GO:0016339; GO:0016358; GO:0035159; GO:0042067; GO:0045773; GO:0048057; GO:0048813; GO:0050770; GO:0050839; GO:0051963; GO:0070593; GO:0098609; GO:1902669 35673 FUN_002813 609 426 237 388 583 ntLink_8:6513841-6529563 D3ZHS6 7.87e-22 Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; erythrocyte differentiation [GO:0030218]; erythrocyte maturation [GO:0043249]; gene expression [GO:0010467]; granulocyte differentiation [GO:0030851]; hematopoietic stem cell homeostasis [GO:0061484]; in utero embryonic development [GO:0001701]; leukocyte proliferation [GO:0070661]; macrophage homeostasis [GO:0061519]; mitotic cell cycle [GO:0000278]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; monoubiquitinated protein deubiquitination [GO:0035520]; myeloid cell apoptotic process [GO:0033028]; negative regulation of DNA-templated transcription [GO:0045892]; neuron cellular homeostasis [GO:0070050]; neutrophil differentiation [GO:0030223]; nucleate erythrocyte differentiation [GO:0043363]; platelet morphogenesis [GO:0036344]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of inflammatory response [GO:0050727]; response to inorganic substance [GO:0010035]; thrombocyte differentiation [GO:0002574]; tissue homeostasis [GO:0001894]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000278; GO:0001558; GO:0001701; GO:0001894; GO:0002574; GO:0003682; GO:0004843; GO:0005634; GO:0005737; GO:0006325; GO:0006511; GO:0008283; GO:0010035; GO:0010467; GO:0016579; GO:0030218; GO:0030223; GO:0030851; GO:0031490; GO:0033028; GO:0035517; GO:0035520; GO:0035522; GO:0035726; GO:0036344; GO:0043249; GO:0043363; GO:0045892; GO:0050727; GO:0051726; GO:0061484; GO:0061519; GO:0070050; GO:0070661; GO:0071108; GO:1900015 35674 FUN_002813 609 426 237 388 583 ntLink_8:6513841-6529563 D3ZHS6 7.87e-22 Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) Rattus norvegicus (Rat) cell population proliferation [GO:0008283]; chromatin organization [GO:0006325]; common myeloid progenitor cell proliferation [GO:0035726]; erythrocyte differentiation [GO:0030218]; erythrocyte maturation [GO:0043249]; gene expression [GO:0010467]; granulocyte differentiation [GO:0030851]; hematopoietic stem cell homeostasis [GO:0061484]; in utero embryonic development [GO:0001701]; leukocyte proliferation [GO:0070661]; macrophage homeostasis [GO:0061519]; mitotic cell cycle [GO:0000278]; monoubiquitinated histone H2A deubiquitination [GO:0035522]; monoubiquitinated protein deubiquitination [GO:0035520]; myeloid cell apoptotic process [GO:0033028]; negative regulation of DNA-templated transcription [GO:0045892]; neuron cellular homeostasis [GO:0070050]; neutrophil differentiation [GO:0030223]; nucleate erythrocyte differentiation [GO:0043363]; platelet morphogenesis [GO:0036344]; protein deubiquitination [GO:0016579]; protein K48-linked deubiquitination [GO:0071108]; regulation of cell cycle [GO:0051726]; regulation of cell growth [GO:0001558]; regulation of cytokine production involved in inflammatory response [GO:1900015]; regulation of inflammatory response [GO:0050727]; response to inorganic substance [GO:0010035]; thrombocyte differentiation [GO:0002574]; tissue homeostasis [GO:0001894]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000278; GO:0001558; GO:0001701; GO:0001894; GO:0002574; GO:0003682; GO:0004843; GO:0005634; GO:0005737; GO:0006325; GO:0006511; GO:0008283; GO:0010035; GO:0010467; GO:0016579; GO:0030218; GO:0030223; GO:0030851; GO:0031490; GO:0033028; GO:0035517; GO:0035520; GO:0035522; GO:0035726; GO:0036344; GO:0043249; GO:0043363; GO:0045892; GO:0050727; GO:0051726; GO:0061484; GO:0061519; GO:0070050; GO:0070661; GO:0071108; GO:1900015 35675 FUN_009844 48 38 14 28 38 NA NA NA NA NA NA NA 35676 FUN_009843 0 0 0 0 22 ptg000004l:12479338-12482402 Q9NY64 1.06e-42 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; glucose transmembrane transport [GO:1904659]; hexose transmembrane transport [GO:0008645]; insulin receptor signaling pathway [GO:0008286]; male meiosis I [GO:0007141]; response to hypoxia [GO:0001666]; transmembrane transport [GO:0055085] GO:0001666; GO:0005353; GO:0005355; GO:0005536; GO:0005765; GO:0005886; GO:0005975; GO:0007141; GO:0008021; GO:0008286; GO:0008645; GO:0015755; GO:0016020; GO:0022857; GO:0030669; GO:0033300; GO:0055056; GO:0055085; GO:0070837; GO:1904659 35677 FUN_002814 34 24 8 6 52 ntLink_8:6533024-6534209 Q9EQD2 6.89e-38 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (Neuropeptide G-protein coupled receptor) Rattus norvegicus (Rat) G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 35678 FUN_009841 244 211 259 263 382 ptg000004l:12436910-12447354 Q9JIF3 3.37e-48 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Mus musculus (Mouse) dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; galactose transmembrane transport [GO:0015757]; glucose metabolic process [GO:0006006]; glucose transmembrane transport [GO:1904659]; insulin receptor signaling pathway [GO:0008286]; male meiosis I [GO:0007141]; response to hypoxia [GO:0001666]; transmembrane transport [GO:0055085] GO:0001666; GO:0005353; GO:0005354; GO:0005355; GO:0005536; GO:0005886; GO:0006006; GO:0007141; GO:0008021; GO:0008286; GO:0015284; GO:0015755; GO:0015757; GO:0016020; GO:0022857; GO:0030659; GO:0033300; GO:0055085; GO:0070837; GO:1904659 35679 FUN_009840 131 122 122 39 152 ptg000004l:12429599-12436102 P58354 1.67e-38 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Bos taurus (Bovine) dehydroascorbic acid transport [GO:0070837]; fructose transmembrane transport [GO:0015755]; glucose transmembrane transport [GO:1904659] GO:0005353; GO:0005355; GO:0005886; GO:0015755; GO:0030659; GO:0033300; GO:0070837; GO:1904659 35680 FUN_005824 3744 2554 1296 1923 1710 NA NA NA NA NA NA NA 35681 FUN_005826 0 14 15 5 35 NA NA NA NA NA NA NA 35682 FUN_032225 300 111 65 135 146 ptg000023l:29884535-29885456 Q5HZI9 5.42e-87 Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 (Mitochondrial NAD(+) transporter SLC25A51) (Mitochondrial carrier triple repeat protein 1) (Solute carrier family 25 member 51) Mus musculus (Mouse) aerobic electron transport chain [GO:0019646]; mitochondrial NAD transmembrane transport [GO:1990549]; mitochondrial transmembrane transport [GO:1990542] GO:0005739; GO:0005743; GO:0019646; GO:0051724; GO:1990542; GO:1990549 35683 FUN_032224 3225 2005 1453 1898 1178 NA NA NA NA NA NA NA 35684 FUN_032226 24 7 0 69 0 NA NA NA NA NA NA NA 35685 FUN_032221 18159 14438 10160 14040 12458 NA NA NA NA NA NA NA 35686 FUN_032220 3792 3582 1762 2728 1791 ptg000023l:29856466-29862755 Q19749 6.19e-38 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) Caenorhabditis elegans acetyl-CoA biosynthetic process from pyruvate [GO:0006086]; glycolytic process [GO:0006096] GO:0004742; GO:0005967; GO:0006086; GO:0006096 35687 FUN_032222 292 120 138 153 170 NA NA NA NA NA NA NA 35688 FUN_029948 5 19 0 0 0 NA NA NA NA NA NA NA 35689 FUN_005822 96 113 66 102 191 ptg000001l:4421050-4448293 P0CT40 4e-78 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 35690 FUN_032229 2653 311 818 2173 410 ptg000023l:29904216-29905377 Q66GV0 2.02e-41 Protein Mpv17 Xenopus laevis (African clawed frog) NA GO:0005743 35691 FUN_032228 227 392 222 351 267 NA NA NA NA NA NA NA 35692 FUN_029177 2307 2033 1621 1752 1836 NA NA NA NA NA NA NA 35693 FUN_029176 263 252 191 361 318 NA NA NA NA NA NA NA 35694 FUN_029170 305 286 260 475 448 NA NA NA NA NA NA NA 35695 FUN_011317 0 1 0 2 6 NA NA NA NA NA NA NA 35696 FUN_011310 0 3 18 1 137 NA NA NA NA NA NA NA 35697 FUN_011318 16 0 0 0 0 ptg000007l:8803939-8807073 Q96DM1 9.56e-24 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 35698 FUN_011318 16 0 0 0 0 ptg000007l:8803939-8807073 Q96DM1 9.56e-24 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 35699 FUN_011318 16 0 0 0 0 ptg000007l:8803939-8807073 Q96DM1 9.56e-24 PiggyBac transposable element-derived protein 4 Homo sapiens (Human) NA NA 35700 FUN_016981 374 183 308 270 136 ptg000011l:9730309-9731785 Q9Y5X5 1.51e-27 Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor) Homo sapiens (Human) detection of abiotic stimulus [GO:0009582]; G protein-coupled receptor signaling pathway [GO:0007186]; regulation of adenylate cyclase activity [GO:0045761]; regulation of cAMP-dependent protein kinase activity [GO:2000479]; regulation of MAPK cascade [GO:0043408] GO:0004930; GO:0005886; GO:0007186; GO:0008188; GO:0009582; GO:0015629; GO:0031628; GO:0042277; GO:0043408; GO:0045761; GO:2000479 35701 FUN_016986 0 0 0 890 386 NA NA NA NA NA NA NA 35702 FUN_016679 208 0 101 239 0 ptg000011l:6225910-6229361 Q08BV2 4.05e-30 tRNA wybutosine-synthesizing protein 5 (EC 1.14.11.42) (tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase) Danio rerio (Zebrafish) (Brachydanio rerio) wybutosine biosynthetic process [GO:0031591] GO:0000049; GO:0005506; GO:0016706; GO:0031591; GO:0042803; GO:0102524 35703 FUN_008718 2223 1273 863 1836 1214 NA NA NA NA NA NA NA 35704 FUN_008719 684 482 342 519 172 NA NA NA NA NA NA NA 35705 FUN_008714 122 43 147 133 120 ptg000002l:14663680-14666751 Q8TF09 1.42e-21 Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2) Homo sapiens (Human) microtubule-based movement [GO:0007018] GO:0003777; GO:0005737; GO:0005813; GO:0005868; GO:0005874; GO:0005929; GO:0007018; GO:0045505; GO:0097542 35706 FUN_008715 118 186 113 64 162 NA NA NA NA NA NA NA 35707 FUN_008716 8574 7648 3744 10662 6801 ptg000002l:14692902-14703690 Q5R7W2 3.08e-26 Phosphate carrier protein, mitochondrial (Phosphate transport protein) (PTP) (Solute carrier family 25 member 3) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) mitochondrial phosphate ion transmembrane transport [GO:1990547] GO:0005315; GO:0005743; GO:0015293; GO:1990547 35708 FUN_008717 33 22 60 49 134 ptg000002l:14714229-14715495 Q2TAR3 3.95e-111 Fez family zinc finger protein 2 Xenopus laevis (African clawed frog) cell differentiation [GO:0030154]; nervous system development [GO:0007399] GO:0003677; GO:0005634; GO:0007399; GO:0030154; GO:0046872 35709 FUN_008710 336 173 196 206 401 ptg000002l:14635694-14639256 Q32PH7 1.19e-23 Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.355) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2) Bos taurus (Bovine) cell cycle [GO:0007049]; cell differentiation [GO:0030154]; chromatin organization [GO:0006325]; histone H3-K9 dimethylation [GO:0036123]; histone H3-K9 trimethylation [GO:0036124]; histone lysine methylation [GO:0034968]; negative regulation of circadian rhythm [GO:0042754]; negative regulation of DNA-templated transcription [GO:0045892]; rhythmic process [GO:0048511] GO:0000775; GO:0000976; GO:0005634; GO:0006325; GO:0007049; GO:0008270; GO:0030154; GO:0034968; GO:0036123; GO:0036124; GO:0042754; GO:0045892; GO:0046974; GO:0048511; GO:0140949 35710 FUN_008711 1858 2227 1137 1286 1387 NA NA NA NA NA NA NA 35711 FUN_008712 4066 3386 1859 3429 3106 NA NA NA NA NA NA NA 35712 FUN_008713 2895 2561 1655 3055 1889 NA NA NA NA NA NA NA 35713 FUN_000523 1330 500 0 0 5 NA NA NA NA NA NA NA 35714 FUN_000522 210 150 0 0 0 ntLink_6:3954197-3955838 Q9BX84 9.07e-22 Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6) Homo sapiens (Human) calcium ion transmembrane transport [GO:0070588]; cation transmembrane transport [GO:0098655]; protein phosphorylation [GO:0006468]; protein tetramerization [GO:0051262]; response to toxic substance [GO:0009636] GO:0004674; GO:0005261; GO:0005262; GO:0005524; GO:0005886; GO:0006468; GO:0009636; GO:0016324; GO:0031526; GO:0046872; GO:0051262; GO:0070588; GO:0098655; GO:0106310 35715 FUN_000521 1325 1178 1415 2433 1019 ntLink_6:3932083-3939414 Q87PP5 1.01e-81 Glycine betaine/proline/choline/ectoine transporter VP1456 Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) amino acid transport [GO:0006865] GO:0005886; GO:0006865; GO:0022857 35716 FUN_000520 918 575 386 975 573 NA NA NA NA NA NA NA 35717 FUN_000526 18 90 64 41 66 NA NA NA NA NA NA NA 35718 FUN_013819 82 0 0 173 43 NA NA NA NA NA NA NA 35719 FUN_013818 20 0 0 321 10 NA NA NA NA NA NA NA 35720 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 2.01e-63 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35721 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 8.72e-51 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35722 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 6.59e-46 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35723 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 6.37e-34 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35724 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 1.01e-29 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35725 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 7.79e-29 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35726 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 1.7e-28 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35727 FUN_014844 1514 696 637 1597 718 ptg000009l:3618892-3629662 Q07954 1.16e-25 Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)] Homo sapiens (Human) amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta clearance by transcytosis [GO:0150093]; aorta morphogenesis [GO:0035909]; apoptotic cell clearance [GO:0043277]; astrocyte activation involved in immune response [GO:0002265]; cellular response to amyloid-beta [GO:1904646]; enzyme-linked receptor protein signaling pathway [GO:0007167]; lipid metabolic process [GO:0006629]; lipoprotein transport [GO:0042953]; lysosomal transport [GO:0007041]; negative regulation of gene expression [GO:0010629]; negative regulation of metallopeptidase activity [GO:1905049]; negative regulation of pathway-restricted SMAD protein phosphorylation [GO:0060394]; negative regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000587]; negative regulation of SMAD protein signal transduction [GO:0060392]; negative regulation of smooth muscle cell migration [GO:0014912]; negative regulation of Wnt signaling pathway [GO:0030178]; phagocytosis [GO:0006909]; positive regulation of amyloid-beta clearance [GO:1900223]; positive regulation of cell death [GO:0010942]; positive regulation of cholesterol efflux [GO:0010875]; positive regulation of cholesterol transport [GO:0032376]; positive regulation of endocytosis [GO:0045807]; positive regulation of lipid transport [GO:0032370]; positive regulation of lysosomal protein catabolic process [GO:1905167]; positive regulation of protein binding [GO:0032092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of transcytosis [GO:1904300]; receptor internalization [GO:0031623]; receptor-mediated endocytosis [GO:0006898]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of cholesterol transport [GO:0032374]; regulation of extracellular matrix disassembly [GO:0010715]; regulation of phospholipase A2 activity [GO:0032429]; retinoid metabolic process [GO:0001523]; transcytosis [GO:0045056]; transport across blood-brain barrier [GO:0150104] GO:0001523; GO:0001540; GO:0002265; GO:0003723; GO:0005041; GO:0005044; GO:0005509; GO:0005634; GO:0005765; GO:0005769; GO:0005794; GO:0005856; GO:0005886; GO:0005905; GO:0005925; GO:0006629; GO:0006898; GO:0006909; GO:0007041; GO:0007167; GO:0010629; GO:0010715; GO:0010875; GO:0010942; GO:0014912; GO:0016020; GO:0016323; GO:0016964; GO:0030178; GO:0030226; GO:0030666; GO:0031623; GO:0032050; GO:0032092; GO:0032370; GO:0032374; GO:0032376; GO:0032429; GO:0032956; GO:0034185; GO:0035909; GO:0038023; GO:0038024; GO:0042953; GO:0043235; GO:0043277; GO:0043395; GO:0044877; GO:0045056; GO:0045807; GO:0060392; GO:0060394; GO:0062136; GO:0070325; GO:0097242; GO:0098797; GO:0150093; GO:0150094; GO:0150104; GO:1900223; GO:1903078; GO:1904300; GO:1904646; GO:1905049; GO:1905167; GO:2000587 35728 FUN_000528 0 2 10 10 6 NA NA NA NA NA NA NA 35729 FUN_014843 3499 4298 2139 3987 4108 ptg000009l:3608965-3617490 Q8K2J9 2.86e-60 BTB/POZ domain-containing protein 6 Mus musculus (Mouse) neurogenesis [GO:0022008] GO:0005829; GO:0022008 35730 FUN_014842 1791 984 771 2091 1152 NA NA NA NA NA NA NA 35731 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 4.4e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35732 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 9.33e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35733 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 1.31e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35734 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 1.85e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35735 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 2.85e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35736 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 1.97e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35737 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 1.97e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35738 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 3.22e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35739 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 5.85e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35740 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 1.01e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35741 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 2.69e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35742 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 3.58e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35743 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 1.91e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35744 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 7.66e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35745 FUN_033178 0 0 7 7 7 ptg000023l:40723698-40729876 Q80XJ3 2e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 35746 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35747 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35748 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35749 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 1.09e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35750 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 5.56e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35751 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 1.83e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35752 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 2.17e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35753 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 1.23e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35754 FUN_033179 55 10 85 248 257 ptg000023l:40747906-40751934 Q96AY4 1.14e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35755 FUN_033172 16 94 29 48 198 NA NA NA NA NA NA NA 35756 FUN_033173 25 4 11 64 11 ptg000023l:40675014-40677813 Q96AY4 6.64e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35757 FUN_033173 25 4 11 64 11 ptg000023l:40675014-40677813 Q96AY4 8.02e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35758 FUN_033173 25 4 11 64 11 ptg000023l:40675014-40677813 Q96AY4 3.21e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35759 FUN_033173 25 4 11 64 11 ptg000023l:40675014-40677813 Q96AY4 2.68e-109 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35760 FUN_033173 25 4 11 64 11 ptg000023l:40675014-40677813 Q96AY4 4.25e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35761 FUN_033173 25 4 11 64 11 ptg000023l:40675014-40677813 Q96AY4 1.82e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35762 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35763 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35764 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35765 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35766 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35767 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35768 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35769 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 7.42e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35770 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 8.87e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35771 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 2.75e-145 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35772 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 4.92e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35773 FUN_033171 39 9 14 90 34 ptg000023l:40625244-40631032 Q96AY4 1.21e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35774 FUN_033177 2 4 0 8 12 ptg000023l:40721621-40723503 Q96AY4 1.87e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35775 FUN_033177 2 4 0 8 12 ptg000023l:40721621-40723503 Q96AY4 5.99e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35776 FUN_033177 2 4 0 8 12 ptg000023l:40721621-40723503 Q96AY4 8.79e-131 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35777 FUN_033177 2 4 0 8 12 ptg000023l:40721621-40723503 Q96AY4 6.11e-130 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35778 FUN_033177 2 4 0 8 12 ptg000023l:40721621-40723503 Q96AY4 2.81e-116 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35779 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.33e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35780 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.33e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35781 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 3.52e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35782 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 6.09e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35783 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.97e-90 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35784 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 8.61e-89 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35785 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 2.06e-88 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35786 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 2.58e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35787 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 7.12e-83 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35788 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 9.28e-80 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35789 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 4.3e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35790 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 7.99e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35791 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 2.19e-73 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35792 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.01e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35793 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.91e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35794 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 4.84e-71 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35795 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.28e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35796 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 5.38e-58 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35797 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 7.4e-35 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35798 FUN_033174 0 0 0 7 30 ptg000023l:40693794-40696610 Q96AY4 1.22e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35799 FUN_028888 2 14 0 3 9 NA NA NA NA NA NA NA 35800 FUN_028889 101 88 35 110 208 NA NA NA NA NA NA NA 35801 FUN_028885 53 0 51 35 62 NA NA NA NA NA NA NA 35802 FUN_016199 71 22 29 57 40 NA NA NA NA NA NA NA 35803 FUN_010548 3 0 9 8 26 NA NA NA NA NA NA NA 35804 FUN_010549 9 0 11 3 51 NA NA NA NA NA NA NA 35805 FUN_010545 0 0 0 0 51 NA NA NA NA NA NA NA 35806 FUN_017004 15 6 0 69 0 ptg000011l:10116816-10121491 Q9YGL3 1.1e-32 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 35807 FUN_017004 15 6 0 69 0 ptg000011l:10116816-10121491 Q9YGL3 4.09e-23 Nuclear receptor subfamily 2 group E member 1 (Nuclear receptor TLX) (Protein tailless homolog) (Tll) Oryzias latipes (Japanese rice fish) (Japanese killifish) anatomical structure development [GO:0048856]; cell differentiation [GO:0030154]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000978; GO:0004879; GO:0005634; GO:0006357; GO:0008270; GO:0030154; GO:0048856 35808 FUN_012037 231 0 64 39 123 NA NA NA NA NA NA NA 35809 FUN_017007 0 0 0 0 14 NA NA NA NA NA NA NA 35810 FUN_012032 1152 758 734 833 460 NA NA NA NA NA NA NA 35811 FUN_012033 2468 1737 924 1739 2149 NA NA NA NA NA NA NA 35812 FUN_012030 249 160 136 197 94 NA NA NA NA NA NA NA 35813 FUN_012031 469 221 224 282 126 NA NA NA NA NA NA NA 35814 FUN_017008 1 8 12 1 5 NA NA NA NA NA NA NA 35815 FUN_017009 0 0 0 12 14 NA NA NA NA NA NA NA 35816 FUN_012038 14 1923 1186 3104 2608 ptg000008l:4352468-4401004 Q8IVG5 1.93e-79 Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like) Homo sapiens (Human) NA GO:0005737; GO:0005739; GO:0005769 35817 FUN_012039 11 14 0 91 135 NA NA NA NA NA NA NA 35818 FUN_023602 0 0 0 0 13 NA NA NA NA NA NA NA 35819 FUN_020937 38 24 8 44 25 NA NA NA NA NA NA NA 35820 FUN_020934 3 16 30 9 2 NA NA NA NA NA NA NA 35821 FUN_020935 3 2 11 17 6 NA NA NA NA NA NA NA 35822 FUN_020932 24 0 19 0 58 NA NA NA NA NA NA NA 35823 FUN_018512 250 20 34 33 42 NA NA NA NA NA NA NA 35824 FUN_012898 0 8 0 0 0 NA NA NA NA NA NA NA 35825 FUN_014069 1 0 0 0 21 NA NA NA NA NA NA NA 35826 FUN_014068 0 0 0 3 20 NA NA NA NA NA NA NA 35827 FUN_014066 35 0 0 0 30 NA NA NA NA NA NA NA 35828 FUN_012899 0 0 40 27 0 NA NA NA NA NA NA NA 35829 FUN_009436 70 80 48 52 68 NA NA NA NA NA NA NA 35830 FUN_009437 303 869 109 221 101 NA NA NA NA NA NA NA 35831 FUN_009430 0 0 0 7 0 NA NA NA NA NA NA NA 35832 FUN_005041 0 0 119 36 63 NA NA NA NA NA NA NA 35833 FUN_009438 1493 669 1132 1076 1146 NA NA NA NA NA NA NA 35834 FUN_009439 370 168 280 467 484 NA NA NA NA NA NA NA 35835 FUN_026426 1230 62 606 1715 609 NA NA NA NA NA NA NA 35836 FUN_026424 0 26 0 93 0 NA NA NA NA NA NA NA 35837 FUN_026422 562 253 246 327 130 NA NA NA NA NA NA NA 35838 FUN_026423 73 95 174 122 48 NA NA NA NA NA NA NA 35839 FUN_026420 48 237 86 145 173 NA NA NA NA NA NA NA 35840 FUN_026421 732 765 623 916 1099 NA NA NA NA NA NA NA 35841 FUN_026428 142 0 436 226 255 NA NA NA NA NA NA NA 35842 FUN_026429 74 329 5 1239 778 NA NA NA NA NA NA NA 35843 FUN_039901 1495 1127 733 991 388 ptg000031l:1517149-1524546 Q9QZU7 3.34e-23 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 35844 FUN_039900 1 2 7 23 3 NA NA NA NA NA NA NA 35845 FUN_039903 4 1 3 9 13 NA NA NA NA NA NA NA 35846 FUN_039902 8 0 0 8 0 NA NA NA NA NA NA NA 35847 FUN_039905 82 142 167 193 303 NA NA NA NA NA NA NA 35848 FUN_039904 48 91 157 115 189 ptg000031l:1534442-1539953 Q9QZU7 3.38e-23 Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) Rattus norvegicus (Rat) carnitine biosynthetic process [GO:0045329] GO:0005506; GO:0005739; GO:0008270; GO:0008336; GO:0042802; GO:0045329 35849 FUN_039907 2 0 0 0 11 NA NA NA NA NA NA NA 35850 FUN_039909 0 0 0 0 26 NA NA NA NA NA NA NA 35851 FUN_022505 191 182 119 175 154 NA NA NA NA NA NA NA 35852 FUN_022504 0 88 67 0 13 NA NA NA NA NA NA NA 35853 FUN_022507 60 62 72 53 119 ptg000016l:9800183-9807835 I0IUP4 1.31e-39 DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0006974; GO:0016887; GO:0032508; GO:0042555; GO:0097362 35854 FUN_022507 60 62 72 53 119 ptg000016l:9800183-9807835 I0IUP4 4.24e-32 DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0006974; GO:0016887; GO:0032508; GO:0042555; GO:0097362 35855 FUN_022507 60 62 72 53 119 ptg000016l:9800183-9807835 I0IUP4 1.2e-30 DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0006974; GO:0016887; GO:0032508; GO:0042555; GO:0097362 35856 FUN_022507 60 62 72 53 119 ptg000016l:9800183-9807835 I0IUP4 1.82e-30 DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0006974; GO:0016887; GO:0032508; GO:0042555; GO:0097362 35857 FUN_022507 60 62 72 53 119 ptg000016l:9800183-9807835 I0IUP4 3e-26 DNA helicase MCM9 (EC 3.6.4.12) (Minichromosome maintenance 9) Gallus gallus (Chicken) cellular response to DNA damage stimulus [GO:0006974]; DNA duplex unwinding [GO:0032508]; double-strand break repair via homologous recombination [GO:0000724] GO:0000724; GO:0003697; GO:0004386; GO:0005524; GO:0005634; GO:0006974; GO:0016887; GO:0032508; GO:0042555; GO:0097362 35858 FUN_022506 617 525 229 507 693 NA NA NA NA NA NA NA 35859 FUN_022501 366 162 188 318 489 ptg000016l:9731731-9747635 O88871 1.47e-24 Gamma-aminobutyric acid type B receptor subunit 2 (GABA-B receptor 2) (GABA-B-R2) (GABA-BR2) (GABABR2) (Gb2) (G-protein coupled receptor 51) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; gamma-aminobutyric acid signaling pathway [GO:0007214]; neuron-glial cell signaling [GO:0150099]; synaptic transmission, GABAergic [GO:0051932] GO:0004888; GO:0004965; GO:0005737; GO:0005886; GO:0007193; GO:0007214; GO:0016020; GO:0030425; GO:0038039; GO:0042734; GO:0043005; GO:0043204; GO:0045211; GO:0046982; GO:0051932; GO:0098978; GO:0098982; GO:0150099; GO:1902710; GO:1902712 35860 FUN_022500 528 147 177 150 178 NA NA NA NA NA NA NA 35861 FUN_022503 4516 3696 1904 2690 1582 NA NA NA NA NA NA NA 35862 FUN_022502 1426 513 675 1737 990 NA NA NA NA NA NA NA 35863 FUN_005047 1675 1129 857 1652 1031 NA NA NA NA NA NA NA 35864 FUN_022509 1198 682 571 970 545 ptg000016l:9815826-9830485 Q5R7D1 8.98e-44 ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein localization [GO:0008104]; regulation of apoptotic process [GO:0042981] GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005737; GO:0008104; GO:0016887; GO:0042981 35865 FUN_015338 1220 901 780 1459 1167 NA NA NA NA NA NA NA 35866 FUN_015339 8717 7961 3192 5205 3038 ptg000009l:9019425-9030537 B3TP03 5.53e-77 Cationic amino acid transporter 2 (CAT-2) (CAT2) (cCAT-2) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) Gallus gallus (Chicken) amino acid transport [GO:0006865]; L-arginine import across plasma membrane [GO:0097638]; L-lysine import across plasma membrane [GO:0097639]; L-ornithine transmembrane transport [GO:1903352] GO:0000064; GO:0005737; GO:0005794; GO:0005886; GO:0006865; GO:0015171; GO:0015189; GO:0031410; GO:0061459; GO:0097638; GO:0097639; GO:1903352 35867 FUN_015335 61 9 31 25 58 NA NA NA NA NA NA NA 35868 FUN_015336 25 18 0 10 18 NA NA NA NA NA NA NA 35869 FUN_015337 9543 3427 6169 6541 3476 NA NA NA NA NA NA NA 35870 FUN_015330 50 53 14 51 5 NA NA NA NA NA NA NA 35871 FUN_015331 47 96 85 33 5 NA NA NA NA NA NA NA 35872 FUN_015332 55 26 25 38 4 NA NA NA NA NA NA NA 35873 FUN_018571 6 0 0 0 5 NA NA NA NA NA NA NA 35874 FUN_017782 589 450 231 480 291 NA NA NA NA NA NA NA 35875 FUN_017787 667 574 375 614 743 NA NA NA NA NA NA NA 35876 FUN_017786 404 289 106 182 111 NA NA NA NA NA NA NA 35877 FUN_017785 0 30 9 14 0 ptg000012l:396291-403346 P27467 5.8e-51 Protein Wnt-3a Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; anterior/posterior pattern specification [GO:0009952]; axis elongation involved in somitogenesis [GO:0090245]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; B cell proliferation [GO:0042100]; BMP signaling pathway [GO:0030509]; calcium ion transmembrane transport via low voltage-gated calcium channel [GO:0090676]; canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment [GO:0061317]; cardiac muscle cell fate commitment [GO:0060923]; cell fate commitment [GO:0045165]; cell population proliferation [GO:0008283]; cell proliferation in forebrain [GO:0021846]; cell proliferation in midbrain [GO:0033278]; cell-cell signaling [GO:0007267]; COP9 signalosome assembly [GO:0010387]; determination of left/right symmetry [GO:0007368]; dopaminergic neuron differentiation [GO:0071542]; dorsal/ventral neural tube patterning [GO:0021904]; extracellular matrix organization [GO:0030198]; fat cell differentiation [GO:0045444]; heart looping [GO:0001947]; hemopoiesis [GO:0030097]; hippocampus development [GO:0021766]; in utero embryonic development [GO:0001701]; inner ear morphogenesis [GO:0042472]; mammary gland development [GO:0030879]; mesoderm development [GO:0007498]; midbrain development [GO:0030901]; modulation of chemical synaptic transmission [GO:0050804]; myoblast differentiation [GO:0045445]; negative regulation of axon extension involved in axon guidance [GO:0048843]; negative regulation of dopaminergic neuron differentiation [GO:1904339]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of heart induction by canonical Wnt signaling pathway [GO:0003136]; negative regulation of neurogenesis [GO:0050768]; negative regulation of neuron death [GO:1901215]; negative regulation of neuron projection development [GO:0010977]; neurogenesis [GO:0022008]; neuron differentiation [GO:0030182]; osteoblast differentiation [GO:0001649]; paraxial mesodermal cell fate commitment [GO:0048343]; platelet activation [GO:0030168]; platelet aggregation [GO:0070527]; positive regulation of B cell proliferation [GO:0030890]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation [GO:2000081]; positive regulation of cardiac muscle cell differentiation [GO:2000727]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cell-cell adhesion mediated by cadherin [GO:2000049]; positive regulation of collateral sprouting in absence of injury [GO:0048697]; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280]; positive regulation of cytokine production [GO:0001819]; positive regulation of dermatome development [GO:0061184]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of gene expression [GO:0010628]; positive regulation of hepatocyte proliferation [GO:2000347]; positive regulation of mesodermal cell fate specification [GO:0048337]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of peptidyl-serine phosphorylation [GO:0033138]; positive regulation of protein binding [GO:0032092]; positive regulation of protein kinase activity [GO:0045860]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein tyrosine kinase activity [GO:0061098]; positive regulation of receptor internalization [GO:0002092]; positive regulation of skeletal muscle tissue development [GO:0048643]; positive regulation of transcription by RNA polymerase II [GO:0045944]; post-anal tail morphogenesis [GO:0036342]; protein localization [GO:0008104]; regulation of axonogenesis [GO:0050770]; regulation of cell differentiation [GO:0045595]; regulation of microtubule cytoskeleton organization [GO:0070507]; regulation of postsynapse to nucleus signaling pathway [GO:1905539]; regulation of presynapse assembly [GO:1905606]; regulation of RNA biosynthetic process [GO:2001141]; regulation of synapse organization [GO:0050807]; secondary palate development [GO:0062009]; signal transduction [GO:0007165]; skeletal muscle cell differentiation [GO:0035914]; somatic stem cell division [GO:0048103]; somitogenesis [GO:0001756]; spinal cord association neuron differentiation [GO:0021527]; transcription by RNA polymerase II [GO:0006366]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in forebrain neuroblast division [GO:0021874] GO:0001649; GO:0001701; GO:0001756; GO:0001819; GO:0001934; GO:0001947; GO:0002092; GO:0003136; GO:0003713; GO:0005102; GO:0005109; GO:0005125; GO:0005576; GO:0005615; GO:0005788; GO:0006366; GO:0007165; GO:0007267; GO:0007368; GO:0007409; GO:0007411; GO:0007498; GO:0008104; GO:0008283; GO:0008284; GO:0009887; GO:0009952; GO:0009986; GO:0010387; GO:0010628; GO:0010977; GO:0016055; GO:0019904; GO:0021527; GO:0021766; GO:0021846; GO:0021874; GO:0021904; GO:0022008; GO:0030097; GO:0030168; GO:0030182; GO:0030198; GO:0030509; GO:0030879; GO:0030890; GO:0030901; GO:0032092; GO:0033138; GO:0033278; GO:0035914; GO:0036342; GO:0039706; GO:0042100; GO:0042472; GO:0042802; GO:0043280; GO:0045165; GO:0045202; GO:0045444; GO:0045445; GO:0045595; GO:0045599; GO:0045860; GO:0045893; GO:0045944; GO:0048018; GO:0048103; GO:0048337; GO:0048343; GO:0048643; GO:0048697; GO:0048843; GO:0050768; GO:0050770; GO:0050804; GO:0050807; GO:0051091; GO:0060070; GO:0060923; GO:0061098; GO:0061184; GO:0061317; GO:0062009; GO:0070507; GO:0070527; GO:0071542; GO:0090245; GO:0090263; GO:0090676; GO:0098978; GO:1901215; GO:1903078; GO:1904339; GO:1905539; GO:1905606; GO:1990851; GO:1990909; GO:2000049; GO:2000081; GO:2000179; GO:2000347; GO:2000727; GO:2001141 35878 FUN_018576 11 0 0 0 4 NA NA NA NA NA NA NA 35879 FUN_018578 13 0 0 7 4 NA NA NA NA NA NA NA 35880 FUN_017789 66 9 4 105 48 NA NA NA NA NA NA NA 35881 FUN_017788 2264 1457 1081 1202 1629 NA NA NA NA NA NA NA 35882 FUN_017875 4 25 2 8 2 NA NA NA NA NA NA NA 35883 FUN_017874 105 48 38 106 97 NA NA NA NA NA NA NA 35884 FUN_041476 11 16 53 52 24 NA NA NA NA NA NA NA 35885 FUN_017876 119 143 106 185 71 NA NA NA NA NA NA NA 35886 FUN_017870 36 3 10 52 70 NA NA NA NA NA NA NA 35887 FUN_017873 13 0 10 2 1 NA NA NA NA NA NA NA 35888 FUN_017872 300 132 391 288 252 NA NA NA NA NA NA NA 35889 FUN_017879 63 144 90 159 117 NA NA NA NA NA NA NA 35890 FUN_017878 3022 1138 652 1371 1270 NA NA NA NA NA NA NA 35891 FUN_030195 41 63 25 43 97 NA NA NA NA NA NA NA 35892 FUN_030197 911 799 0 775 373 NA NA NA NA NA NA NA 35893 FUN_030196 2447 953 662 1820 1146 NA NA NA NA NA NA NA 35894 FUN_030191 1437 2819 287 9965 3871 ptg000023l:10198002-10204078 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35895 FUN_030191 1437 2819 287 9965 3871 ptg000023l:10198002-10204078 Q96AY4 1.21e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 35896 FUN_030190 44 0 11 36 17 NA NA NA NA NA NA NA 35897 FUN_030199 90 30 131 131 59 NA NA NA NA NA NA NA 35898 FUN_030198 595 435 606 1264 1039 ptg000023l:10269056-10296412 Q9ERH8 3.71e-25 Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (mCNT3) Mus musculus (Mouse) nucleoside transmembrane transport [GO:1901642]; purine nucleoside transmembrane transport [GO:0015860]; pyrimidine nucleoside transport [GO:0015864]; pyrimidine-containing compound transmembrane transport [GO:0072531]; retina homeostasis [GO:0001895]; uridine transport [GO:0015862] GO:0001895; GO:0005337; GO:0005415; GO:0005886; GO:0015213; GO:0015293; GO:0015389; GO:0015390; GO:0015860; GO:0015862; GO:0015864; GO:0031526; GO:0072531; GO:1901642 35899 FUN_031828 8 0 0 0 6 NA NA NA NA NA NA NA 35900 FUN_031829 0 18 57 9 67 NA NA NA NA NA NA NA 35901 FUN_031826 1 0 58 7 90 NA NA NA NA NA NA NA 35902 FUN_031827 8 0 11 19 0 NA NA NA NA NA NA NA 35903 FUN_031824 0 0 16 0 37 NA NA NA NA NA NA NA 35904 FUN_031825 20 0 108 0 45 NA NA NA NA NA NA NA 35905 FUN_031823 0 0 0 0 6 NA NA NA NA NA NA NA 35906 FUN_031820 13 0 0 0 0 NA NA NA NA NA NA NA 35907 FUN_016146 14 0 25 0 52 NA NA NA NA NA NA NA 35908 FUN_016147 8666 10032 7900 4343 4426 NA NA NA NA NA NA NA 35909 FUN_016142 55 39 31 55 31 ptg000010l:2045460-2050878 E9PSL7 9.81e-29 Citron rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21) Rattus norvegicus (Rat) dendrite development [GO:0016358]; G2/M transition of mitotic cell cycle [GO:0000086]; generation of neurons [GO:0048699]; Golgi organization [GO:0007030]; liver development [GO:0001889]; metaphase/anaphase transition of mitotic cell cycle [GO:0007091]; mitotic cell cycle [GO:0000278]; mitotic cytokinesis [GO:0000281]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of dendrite morphogenesis [GO:0050774]; negative regulation of hippo signaling [GO:0035331]; neuron apoptotic process [GO:0051402]; positive regulation of cytokinesis [GO:0032467]; protein phosphorylation [GO:0006468]; regulation of actin polymerization or depolymerization [GO:0008064]; spermatogenesis [GO:0007283] GO:0000070; GO:0000086; GO:0000278; GO:0000281; GO:0001223; GO:0001726; GO:0001889; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0005773; GO:0005829; GO:0005886; GO:0006468; GO:0007030; GO:0007091; GO:0007283; GO:0008064; GO:0015629; GO:0016358; GO:0019901; GO:0030165; GO:0030291; GO:0030496; GO:0031985; GO:0032154; GO:0032467; GO:0035331; GO:0043025; GO:0046872; GO:0048699; GO:0050774; GO:0051402; GO:0097110; GO:0106310 35910 FUN_038692 134 149 77 35 27 NA NA NA NA NA NA NA 35911 FUN_038693 160 214 310 71 129 NA NA NA NA NA NA NA 35912 FUN_038690 1072 1607 932 1137 908 NA NA NA NA NA NA NA 35913 FUN_038691 1544 1690 893 1699 1303 NA NA NA NA NA NA NA 35914 FUN_038696 62 90 18 21 11 NA NA NA NA NA NA NA 35915 FUN_038697 1172 614 653 650 1149 NA NA NA NA NA NA NA 35916 FUN_038694 638 285 1273 31 318 NA NA NA NA NA NA NA 35917 FUN_038695 2701 3192 1649 4432 2740 NA NA NA NA NA NA NA 35918 FUN_038698 7 24 5 41 63 NA NA NA NA NA NA NA 35919 FUN_038699 127 449 230 1058 514 ptg000027l:10310266-10311741 Q49SH1 6.19e-87 Sodium/potassium/calcium exchanger 5 (Na(+)/K(+)/Ca(2+)-exchange protein 5) (Protein golden) (Solute carrier family 24 member 5) Danio rerio (Zebrafish) (Brachydanio rerio) calcium ion transport [GO:0006816]; potassium ion transport [GO:0006813]; response to stimulus [GO:0050896]; sodium ion transport [GO:0006814] GO:0005794; GO:0006813; GO:0006814; GO:0006816; GO:0015293; GO:0015297; GO:0016020; GO:0042470; GO:0050896 35920 FUN_028228 30 21 19 81 63 NA NA NA NA NA NA NA 35921 FUN_035349 2433 1605 1347 2764 2301 ptg000025l:6601430-6614789 P41512 4.41e-22 DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) Xenopus laevis (African clawed frog) chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; DNA topological change [GO:0006265] GO:0000978; GO:0003917; GO:0005634; GO:0005694; GO:0006265; GO:0006338; GO:0032922 35922 FUN_035349 2433 1605 1347 2764 2301 ptg000025l:6601430-6614789 P41512 1.01e-21 DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) Xenopus laevis (African clawed frog) chromatin remodeling [GO:0006338]; circadian regulation of gene expression [GO:0032922]; DNA topological change [GO:0006265] GO:0000978; GO:0003917; GO:0005634; GO:0005694; GO:0006265; GO:0006338; GO:0032922 35923 FUN_035348 6138 7132 1505 4478 837 NA NA NA NA NA NA NA 35924 FUN_016148 758 561 634 789 1297 ptg000010l:2103036-2124529 P79987 8.77e-48 Protein HIRA (cHIRA) (TUP1-like enhancer of split protein 1) Gallus gallus (Chicken) chromatin organization [GO:0006325]; DNA-templated transcription [GO:0006351]; regulation of DNA-templated transcription [GO:0006355] GO:0000417; GO:0005634; GO:0006325; GO:0006351; GO:0006355 35925 FUN_035343 108 52 91 51 52 NA NA NA NA NA NA NA 35926 FUN_035342 151 43 51 122 86 NA NA NA NA NA NA NA 35927 FUN_035341 129 115 135 193 271 NA NA NA NA NA NA NA 35928 FUN_044241 27 87 58 84 207 NA NA NA NA NA NA NA 35929 FUN_035347 3146 1810 1689 1952 873 NA NA NA NA NA NA NA 35930 FUN_044247 0 0 1 6 1 NA NA NA NA NA NA NA 35931 FUN_035345 50 34 92 84 49 NA NA NA NA NA NA NA 35932 FUN_035344 126 17 0 49 50 NA NA NA NA NA NA NA 35933 FUN_015980 1488 2053 1622 2144 1098 NA NA NA NA NA NA NA 35934 FUN_036697 0 6 2 0 7 NA NA NA NA NA NA NA 35935 FUN_001924 196 7 207 49 497 NA NA NA NA NA NA NA 35936 FUN_001925 4 0 40 7 232 NA NA NA NA NA NA NA 35937 FUN_001927 0 0 0 0 34 NA NA NA NA NA NA NA 35938 FUN_001922 0 0 13 21 36 NA NA NA NA NA NA NA 35939 FUN_001923 0 0 94 16 111 NA NA NA NA NA NA NA 35940 FUN_015984 4680 2452 2262 3442 1767 NA NA NA NA NA NA NA 35941 FUN_001929 0 0 0 14 79 NA NA NA NA NA NA NA 35942 FUN_036945 0 0 0 9 0 NA NA NA NA NA NA NA 35943 FUN_030449 9 0 10 0 35 ptg000023l:10890532-10891295 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35944 FUN_030447 7 0 14 1 36 ptg000023l:10886480-10887243 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35945 FUN_030445 6 0 6 0 38 ptg000023l:10882428-10883191 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35946 FUN_030443 7 0 6 0 39 ptg000023l:10878376-10879139 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35947 FUN_030441 11 2 10 1 47 ptg000023l:10874324-10875087 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 35948 FUN_018328 0 22 0 0 3 NA NA NA NA NA NA NA 35949 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 4.52e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35950 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 4.52e-48 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35951 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 2.06e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35952 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 2.06e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35953 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 3.51e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35954 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 3.51e-40 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35955 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 1.42e-29 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35956 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 1.1e-26 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35957 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 1.62e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35958 FUN_031316 382 112 184 10 289 ptg000023l:19332431-19344368 Q7RTR2 2.47e-21 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35959 FUN_031310 720 462 799 623 873 ptg000023l:19255210-19261075 Q5DU56 1.86e-30 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35960 FUN_031310 720 462 799 623 873 ptg000023l:19255210-19261075 Q5DU56 1.32e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35961 FUN_031310 720 462 799 623 873 ptg000023l:19255210-19261075 Q5DU56 4.74e-28 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35962 FUN_031310 720 462 799 623 873 ptg000023l:19255210-19261075 Q5DU56 4.01e-26 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35963 FUN_031310 720 462 799 623 873 ptg000023l:19255210-19261075 Q5DU56 5.44e-25 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35964 FUN_031310 720 462 799 623 873 ptg000023l:19255210-19261075 Q5DU56 5.07e-21 Protein NLRC3 Mus musculus (Mouse) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-1 beta production [GO:0032691]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; regulation of protein ubiquitination [GO:0031396]; response to lipopolysaccharide [GO:0032496]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0031396; GO:0032088; GO:0032496; GO:0032687; GO:0032688; GO:0032691; GO:0032695; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 35965 FUN_034359 2095 1361 1720 2340 2004 NA NA NA NA NA NA NA 35966 FUN_031312 14 31 20 17 17 ptg000023l:19269539-19275575 Q4R4A8 3.71e-63 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc) (GnT-IVc) (N-acetylglucosaminyltransferase IVc) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) protein glycosylation [GO:0006486] GO:0000139; GO:0006486; GO:0008454; GO:0046872 35967 FUN_037877 4135 1095 2094 3748 3974 NA NA NA NA NA NA NA 35968 FUN_037876 5679 2252 3227 3821 3236 NA NA NA NA NA NA NA 35969 FUN_037875 3054 1872 3050 3105 1596 NA NA NA NA NA NA NA 35970 FUN_037871 44 61 59 74 21 ptg000026l:14567600-14570429 Q9P2E2 8.97e-151 Kinesin-like protein KIF17 (KIF3-related motor protein) Homo sapiens (Human) anterograde dendritic transport of neurotransmitter receptor complex [GO:0098971]; cell projection organization [GO:0030030]; microtubule-based movement [GO:0007018]; protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GO:0001750; GO:0001917; GO:0003777; GO:0005524; GO:0005815; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0005930; GO:0007018; GO:0008017; GO:0008574; GO:0015031; GO:0016192; GO:0016887; GO:0030030; GO:0032391; GO:0032839; GO:0036064; GO:0043005; GO:0098971; GO:1990075 35971 FUN_037870 3927 3606 1988 3065 1903 NA NA NA NA NA NA NA 35972 FUN_037879 156 174 78 120 98 NA NA NA NA NA NA NA 35973 FUN_010758 605 525 85 360 160 NA NA NA NA NA NA NA 35974 FUN_027292 215 823 707 188 29 NA NA NA NA NA NA NA 35975 FUN_027293 11 11 20 33 6 NA NA NA NA NA NA NA 35976 FUN_027290 9 2 9 8 3 NA NA NA NA NA NA NA 35977 FUN_027291 28 31 60 105 0 ptg000021l:3121310-3143532 Q96MB7 1.07e-49 Putative nuclease HARBI1 (EC 3.1.-.-) (Harbinger transposase-derived nuclease) Homo sapiens (Human) NA GO:0004518; GO:0005634; GO:0005829; GO:0005886; GO:0034451; GO:0046872 35978 FUN_027295 35 5 21 31 13 NA NA NA NA NA NA NA 35979 FUN_027298 0 0 87 4 0 NA NA NA NA NA NA NA 35980 FUN_017294 1061 82 0 57 37 NA NA NA NA NA NA NA 35981 FUN_012665 0 0 0 0 101 NA NA NA NA NA NA NA 35982 FUN_036093 2434 3192 3067 5517 4398 NA NA NA NA NA NA NA 35983 FUN_012663 25 33 154 181 258 NA NA NA NA NA NA NA 35984 FUN_012662 684 326 236 648 338 ptg000008l:11033405-11040019 Q8BZ20 5.43e-36 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 35985 FUN_012662 684 326 236 648 338 ptg000008l:11033405-11040019 Q8BZ20 5.99e-23 Protein mono-ADP-ribosyltransferase PARP12 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 12) (ARTD12) (Poly [ADP-ribose] polymerase 12) (PARP-12) (Zinc finger CCCH domain-containing protein 1) Mus musculus (Mouse) protein auto-ADP-ribosylation [GO:0070213] GO:0003950; GO:0005634; GO:0016779; GO:0046872; GO:0070213; GO:0140803; GO:1990404 35986 FUN_037257 0 9 0 0 0 NA NA NA NA NA NA NA 35987 FUN_037256 0 15 0 10 0 NA NA NA NA NA NA NA 35988 FUN_037255 0 9 0 0 28 NA NA NA NA NA NA NA 35989 FUN_037254 0 8 0 0 0 NA NA NA NA NA NA NA 35990 FUN_017292 0 0 0 0 8 NA NA NA NA NA NA NA 35991 FUN_006718 2656 1473 1377 2267 2364 NA NA NA NA NA NA NA 35992 FUN_006719 16011 13879 8317 12216 9411 NA NA NA NA NA NA NA 35993 FUN_005357 2260 2718 1469 1683 631 NA NA NA NA NA NA NA 35994 FUN_005356 1768 2122 1249 2112 1485 ntLink_8:34371714-34376456 Q6AX59 3.92e-22 Protein ABHD8 (EC 3.-.-.-) (Alpha/beta hydrolase domain-containing protein 8) (Abhydrolase domain-containing protein 8) Xenopus laevis (African clawed frog) NA GO:0016787 35995 FUN_005355 1106 967 884 753 701 ntLink_8:34356548-34367100 Q2TBL4 1.24e-33 DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) Bos taurus (Bovine) defense response to virus [GO:0051607]; DNA-templated transcription [GO:0006351]; innate immune response [GO:0045087]; positive regulation of innate immune response [GO:0045089]; positive regulation of interferon-beta production [GO:0032728] GO:0003697; GO:0005654; GO:0005666; GO:0006351; GO:0032728; GO:0045087; GO:0045089; GO:0051607 35996 FUN_005354 3676 3995 2724 3347 2050 NA NA NA NA NA NA NA 35997 FUN_005353 1405 1434 958 1105 582 NA NA NA NA NA NA NA 35998 FUN_005352 354 554 249 416 390 ntLink_8:34319337-34343767 Q9W0Y8 2.72e-26 Sodium channel protein 60E (Drosophila ion channel 60) (Drosophila sodium channel 1) (Protein smell-impaired 60E) (Sodium channel 2) (DmNav2) Drosophila melanogaster (Fruit fly) membrane depolarization during action potential [GO:0086010]; neuronal action potential [GO:0019228]; olfactory behavior [GO:0042048]; regulation of ion transmembrane transport [GO:0034765]; sensory perception of smell [GO:0007608]; sodium ion transmembrane transport [GO:0035725]; sodium ion transport [GO:0006814] GO:0001518; GO:0005248; GO:0005886; GO:0006814; GO:0007608; GO:0019228; GO:0022843; GO:0034765; GO:0035725; GO:0042048; GO:0086010 35999 FUN_005351 249 374 113 299 306 ntLink_8:34313689-34314568 Q05973 3.3e-79 Sodium channel protein 1 brain (Sodium channel protein I brain) Heterololigo bleekeri (Spear squid) (Loligo bleekeri) regulation of ion transmembrane transport [GO:0034765] GO:0001518; GO:0005244; GO:0005248; GO:0034765 36000 FUN_005350 742 359 399 685 688 NA NA NA NA NA NA NA 36001 FUN_023014 1038 1202 581 903 1141 NA NA NA NA NA NA NA 36002 FUN_005358 0 6 0 0 0 NA NA NA NA NA NA NA 36003 FUN_004404 0 58 0 14 0 NA NA NA NA NA NA NA 36004 FUN_004405 1093 1142 654 795 917 NA NA NA NA NA NA NA 36005 FUN_005167 850 672 816 1258 567 NA NA NA NA NA NA NA 36006 FUN_004407 1673 1523 547 1242 995 ntLink_8:22945099-22946279 Q6DHU8 2.79e-75 Lymphokine-activated killer T-cell-originated protein kinase homolog (EC 2.7.12.2) (PDZ-binding kinase) Danio rerio (Zebrafish) (Brachydanio rerio) p38MAPK cascade [GO:0038066]; peptidyl-serine phosphorylation [GO:0018105]; positive regulation of mitotic DNA damage checkpoint [GO:1904291] GO:0004674; GO:0004706; GO:0004708; GO:0004713; GO:0005524; GO:0018105; GO:0038066; GO:0106310; GO:1904291 36007 FUN_004400 2086 1495 1207 3088 2624 NA NA NA NA NA NA NA 36008 FUN_004401 25 27 83 64 124 NA NA NA NA NA NA NA 36009 FUN_004402 124 97 68 120 163 NA NA NA NA NA NA NA 36010 FUN_004403 88 0 0 34 0 NA NA NA NA NA NA NA 36011 FUN_004408 128 378 4 52 354 NA NA NA NA NA NA NA 36012 FUN_004409 891 367 590 564 980 NA NA NA NA NA NA NA 36013 FUN_032759 657 639 380 623 139 ptg000023l:35718412-35720945 Q9NVD3 5.61e-30 SET domain-containing protein 4 (EC 2.1.1.-) (EC 2.1.1.364) Homo sapiens (Human) histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; inflammatory response [GO:0006954]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell proliferation in bone marrow [GO:0071863] GO:0005634; GO:0005829; GO:0006954; GO:0016279; GO:0018023; GO:0018026; GO:0032755; GO:0032760; GO:0042799; GO:0042800; GO:0044648; GO:0050729; GO:0071863; GO:0097692; GO:0140941; GO:0140944; GO:0140945 36014 FUN_032758 21 17 25 48 24 NA NA NA NA NA NA NA 36015 FUN_032755 4713 4019 2072 4056 3253 NA NA NA NA NA NA NA 36016 FUN_032754 955 401 309 367 419 ptg000023l:35616446-35668407 P14381 2.46e-111 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 36017 FUN_032757 586 475 507 721 97 ptg000023l:35710032-35712443 Q9NVD3 1.74e-29 SET domain-containing protein 4 (EC 2.1.1.-) (EC 2.1.1.364) Homo sapiens (Human) histone H3-K4 dimethylation [GO:0044648]; histone H3-K4 monomethylation [GO:0097692]; inflammatory response [GO:0006954]; peptidyl-lysine monomethylation [GO:0018026]; peptidyl-lysine trimethylation [GO:0018023]; positive regulation of inflammatory response [GO:0050729]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of cell proliferation in bone marrow [GO:0071863] GO:0005634; GO:0005829; GO:0006954; GO:0016279; GO:0018023; GO:0018026; GO:0032755; GO:0032760; GO:0042799; GO:0042800; GO:0044648; GO:0050729; GO:0071863; GO:0097692; GO:0140941; GO:0140944; GO:0140945 36018 FUN_032756 69 661 319 571 488 NA NA NA NA NA NA NA 36019 FUN_032751 214 70 136 65 178 NA NA NA NA NA NA NA 36020 FUN_032750 2378 1329 1228 2271 2105 NA NA NA NA NA NA NA 36021 FUN_032753 183 125 72 61 31 NA NA NA NA NA NA NA 36022 FUN_032752 62 0 101 19 182 NA NA NA NA NA NA NA 36023 FUN_028518 0 0 0 6 0 ptg000022l:9169-11963 Q5F4A1 1.06e-42 G2/M phase-specific E3 ubiquitin-protein ligase (EC 2.3.2.26) (G2/M phase-specific HECT-type E3 ubiquitin transferase) Gallus gallus (Chicken) apoptotic process [GO:0006915] GO:0004842; GO:0005634; GO:0005730; GO:0005737; GO:0006915; GO:0046872 36024 FUN_028519 0 9 0 6 0 NA NA NA NA NA NA NA 36025 FUN_034753 0 0 0 0 42 NA NA NA NA NA NA NA 36026 FUN_028515 115 796 1503 484 424 NA NA NA NA NA NA NA 36027 FUN_034758 0 2162 0 554 410 NA NA NA NA NA NA NA 36028 FUN_036497 36 8 22 7 1 NA NA NA NA NA NA NA 36029 FUN_022053 354 214 220 291 286 NA NA NA NA NA NA NA 36030 FUN_002769 112 61 82 66 45 NA NA NA NA NA NA NA 36031 FUN_022052 48 84 43 108 51 ptg000016l:5094724-5096377 B0UYT5 9.2e-59 Major facilitator superfamily domain-containing protein 6-B (Macrophage MHC class I receptor 2 homolog B) Danio rerio (Zebrafish) (Brachydanio rerio) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 36032 FUN_002762 5 2 6 2 11 NA NA NA NA NA NA NA 36033 FUN_002761 25 27 2 5 0 NA NA NA NA NA NA NA 36034 FUN_002760 819 6 2 500 8 NA NA NA NA NA NA NA 36035 FUN_002767 3031 2510 2177 2680 2988 NA NA NA NA NA NA NA 36036 FUN_022051 733 618 456 436 270 NA NA NA NA NA NA NA 36037 FUN_022056 7601 8756 3880 5942 5325 NA NA NA NA NA NA NA 36038 FUN_031190 1382 508 660 2034 1273 ptg000023l:17552565-17638291 P20825 3.65e-47 Retrovirus-related Pol polyprotein from transposon 297 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 36039 FUN_022055 4289 2839 1900 2686 2900 ptg000016l:5106160-5121204 Q1LVN8 4.83e-29 Protein adenylyltransferase SelO-1, mitochondrial (EC 2.7.7.108) (Selenoprotein O) (SelO) Danio rerio (Zebrafish) (Brachydanio rerio) NA GO:0005524; GO:0005739; GO:0016779; GO:0046872 36040 FUN_022054 5128 5878 4035 4481 3308 NA NA NA NA NA NA NA 36041 FUN_033402 5 0 3 0 16 NA NA NA NA NA NA NA 36042 FUN_001157 8006 10874 5024 6596 5075 ntLink_6:9198718-9207849 Q7TN33 4.31e-23 CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6) Mus musculus (Mouse) mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; synaptic transmission, serotonergic [GO:0099153]; vocalization behavior [GO:0071625] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006376; GO:0045202; GO:0071625; GO:0099153; GO:1990904 36043 FUN_001157 8006 10874 5024 6596 5075 ntLink_6:9198718-9207849 Q7TN33 4.31e-23 CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6) Mus musculus (Mouse) mRNA splice site selection [GO:0006376]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; synaptic transmission, serotonergic [GO:0099153]; vocalization behavior [GO:0071625] GO:0000381; GO:0003723; GO:0003729; GO:0005634; GO:0005737; GO:0006376; GO:0045202; GO:0071625; GO:0099153; GO:1990904 36044 FUN_001159 195 186 142 173 243 NA NA NA NA NA NA NA 36045 FUN_001158 768 616 398 554 514 ntLink_6:9209888-9211469 Q7ZXG7 1.28e-55 Guanidinoacetate N-methyltransferase A (EC 2.1.1.2) Xenopus laevis (African clawed frog) creatine biosynthetic process [GO:0006601]; methylation [GO:0032259] GO:0006601; GO:0030731; GO:0032259 36046 FUN_001158 768 616 398 554 514 ntLink_6:9209888-9211469 Q7ZXG7 4.81e-46 Guanidinoacetate N-methyltransferase A (EC 2.1.1.2) Xenopus laevis (African clawed frog) creatine biosynthetic process [GO:0006601]; methylation [GO:0032259] GO:0006601; GO:0030731; GO:0032259 36047 FUN_002499 1313 61 90 208 159 NA NA NA NA NA NA NA 36048 FUN_028654 9 4 1 2 1 NA NA NA NA NA NA NA 36049 FUN_002495 197 0 0 1 0 NA NA NA NA NA NA NA 36050 FUN_002494 957 122 64 188 72 NA NA NA NA NA NA NA 36051 FUN_002497 410 183 174 112 145 NA NA NA NA NA NA NA 36052 FUN_002491 299 18 128 203 127 NA NA NA NA NA NA NA 36053 FUN_002490 271 31 340 18 11 NA NA NA NA NA NA NA 36054 FUN_002493 158 93 312 144 144 NA NA NA NA NA NA NA 36055 FUN_002492 1312 756 317 968 452 NA NA NA NA NA NA NA 36056 FUN_000400 9253 6462 2803 4396 5853 NA NA NA NA NA NA NA 36057 FUN_000401 940 869 328 1235 746 ntLink_6:2436694-2439803 Q8N6G5 2.24e-45 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2) Homo sapiens (Human) chondroitin sulfate biosynthetic process [GO:0030206]; chondroitin sulfate proteoglycan biosynthetic process [GO:0050650]; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050653]; dermatan sulfate proteoglycan biosynthetic process [GO:0050651]; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0050652]; proteoglycan biosynthetic process [GO:0030166] GO:0000139; GO:0008376; GO:0016020; GO:0030166; GO:0030206; GO:0032580; GO:0046872; GO:0047237; GO:0047238; GO:0050650; GO:0050651; GO:0050652; GO:0050653 36058 FUN_000402 8020 5637 2559 2988 1754 NA NA NA NA NA NA NA 36059 FUN_000403 14347 8444 7260 12116 10405 NA NA NA NA NA NA NA 36060 FUN_000404 2229 704 904 2660 1575 NA NA NA NA NA NA NA 36061 FUN_000405 204 180 63 91 67 NA NA NA NA NA NA NA 36062 FUN_000406 1091 282 599 499 1266 NA NA NA NA NA NA NA 36063 FUN_000407 846 234 518 683 594 NA NA NA NA NA NA NA 36064 FUN_000408 2943 2619 1101 1812 2089 NA NA NA NA NA NA NA 36065 FUN_000409 1109 853 763 1122 910 NA NA NA NA NA NA NA 36066 FUN_035805 5217 6696 3019 5463 2976 ptg000025l:11922093-11926283 A5PLL7 2.95e-88 Plasmanylethanolamine desaturase (EC 1.14.19.77) (Plasmanylethanolamine desaturase 1) (Transmembrane protein 189) Homo sapiens (Human) ether lipid biosynthetic process [GO:0008611]; fatty acid metabolic process [GO:0006631] GO:0005783; GO:0005789; GO:0006631; GO:0008611; GO:0016491; GO:0050207 36067 FUN_035806 596 526 165 623 603 NA NA NA NA NA NA NA 36068 FUN_035807 216 242 2174 137 2806 NA NA NA NA NA NA NA 36069 FUN_035800 1438 453 417 324 558 NA NA NA NA NA NA NA 36070 FUN_035801 466 661 270 459 309 NA NA NA NA NA NA NA 36071 FUN_035802 4214 2714 3113 6385 4618 NA NA NA NA NA NA NA 36072 FUN_035803 56 71 32 155 39 NA NA NA NA NA NA NA 36073 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36074 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36075 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 0 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36076 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 3.64e-121 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36077 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.63e-90 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36078 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.44e-85 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36079 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.66e-79 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36080 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.23e-72 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36081 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.12e-71 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36082 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 7.64e-64 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36083 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 9.16e-62 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36084 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.64e-55 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36085 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.92e-54 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36086 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 3.93e-42 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36087 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.13e-41 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36088 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 6.24e-39 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36089 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 3.29e-38 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36090 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 6.86e-37 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36091 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.52e-36 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36092 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 7.37e-35 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36093 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.54e-33 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36094 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.54e-32 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36095 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.18e-30 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36096 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 3.61e-30 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36097 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 3.86e-30 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36098 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 7.02e-28 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36099 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.78e-27 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36100 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 1.94e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36101 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 4.18e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36102 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 6.8e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36103 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 8.88e-25 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36104 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 9.88e-24 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36105 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 5.17e-23 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36106 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 5.25e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36107 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 6.98e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36108 FUN_035808 9033 4042 4445 8370 7346 ptg000025l:11955002-11988551 B8V7Q1 2.62e-21 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36109 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 4.93e-72 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36110 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 3.51e-64 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36111 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 9.17e-39 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36112 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 7.15e-35 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36113 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 4.46e-32 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36114 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 4.62e-28 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36115 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 3.01e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36116 FUN_035809 247 45 28 126 146 ptg000025l:11995244-12019556 B8V7Q1 5.49e-22 Protocadherin-like protein Acropora millepora (Staghorn coral) (Heteropora millepora) homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156] GO:0005509; GO:0005886; GO:0007156 36117 FUN_029337 1268 495 480 777 814 ptg000023l:683363-700716 Q9NXK8 3.36e-26 F-box/LRR-repeat protein 12 (F-box and leucine-rich repeat protein 12) (F-box protein FBL12) Homo sapiens (Human) entrainment of circadian clock by photoperiod [GO:0043153]; G2/M transition of mitotic cell cycle [GO:0000086]; protein ubiquitination [GO:0016567]; regulation of cell cycle [GO:0051726]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0000086; GO:0005634; GO:0005829; GO:0016567; GO:0019005; GO:0031146; GO:0043153; GO:0051726 36118 FUN_029336 406 148 168 241 520 NA NA NA NA NA NA NA 36119 FUN_029335 50 64 42 48 56 NA NA NA NA NA NA NA 36120 FUN_029334 24 0 0 0 2 NA NA NA NA NA NA NA 36121 FUN_029333 495 174 167 377 339 NA NA NA NA NA NA NA 36122 FUN_029332 475 248 218 227 209 NA NA NA NA NA NA NA 36123 FUN_029331 424 135 190 255 273 NA NA NA NA NA NA NA 36124 FUN_029330 1705 792 698 1318 837 NA NA NA NA NA NA NA 36125 FUN_029339 3004 1146 988 1514 852 ptg000023l:757033-769220 Q24488 6.32e-57 Tyrosine-protein kinase transmembrane receptor Ror (dRor) (EC 2.7.10.1) Drosophila melanogaster (Fruit fly) central nervous system development [GO:0007417]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004714; GO:0005524; GO:0005886; GO:0006468; GO:0007169; GO:0007417; GO:0010976; GO:0014068; GO:0016020; GO:0017147; GO:0033674; GO:0043235 36126 FUN_029338 5484 1383 2780 5644 3134 ptg000023l:721082-751497 Q24488 1.17e-65 Tyrosine-protein kinase transmembrane receptor Ror (dRor) (EC 2.7.10.1) Drosophila melanogaster (Fruit fly) central nervous system development [GO:0007417]; positive regulation of kinase activity [GO:0033674]; positive regulation of neuron projection development [GO:0010976]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; protein phosphorylation [GO:0006468]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0004713; GO:0004714; GO:0005524; GO:0005886; GO:0006468; GO:0007169; GO:0007417; GO:0010976; GO:0014068; GO:0016020; GO:0017147; GO:0033674; GO:0043235 36127 FUN_012548 2546 1996 1603 1788 1828 ptg000008l:9800859-9805699 Q8NBP5 5.84e-39 Major facilitator superfamily domain-containing protein 9 Homo sapiens (Human) NA GO:0016020; GO:0022857 36128 FUN_012549 10 59 12 17 30 NA NA NA NA NA NA NA 36129 FUN_012546 817 549 540 959 1142 NA NA NA NA NA NA NA 36130 FUN_012547 4274 3189 2201 2588 1728 NA NA NA NA NA NA NA 36131 FUN_012544 541 243 190 252 223 NA NA NA NA NA NA NA 36132 FUN_012545 968 857 824 1382 1092 ptg000008l:9766834-9782809 Q5DTY9 2.75e-45 BTB/POZ domain-containing protein KCTD16 Mus musculus (Mouse) protein homooligomerization [GO:0051260]; regulation of G protein-coupled receptor signaling pathway [GO:0008277] GO:0008277; GO:0042734; GO:0042995; GO:0043235; GO:0045211; GO:0051260 36133 FUN_012542 1873 879 802 885 412 ptg000008l:9750443-9753026 O15442 8.82e-33 Metallophosphoesterase domain-containing protein 1 (EC 3.1.-.-) (Adult brain protein 239) (239AB) Homo sapiens (Human) NA GO:0016787 36134 FUN_012543 2642 894 595 847 535 NA NA NA NA NA NA NA 36135 FUN_012540 0 0 0 0 36 NA NA NA NA NA NA NA 36136 FUN_012541 984 701 567 906 518 NA NA NA NA NA NA NA 36137 FUN_016258 2 0 1 8 4 NA NA NA NA NA NA NA 36138 FUN_016259 40 46 8 90 74 NA NA NA NA NA NA NA 36139 FUN_016256 0 0 0 10 0 NA NA NA NA NA NA NA 36140 FUN_016257 77 43 10 64 81 NA NA NA NA NA NA NA 36141 FUN_016255 0 0 0 7 20 NA NA NA NA NA NA NA 36142 FUN_016252 837 436 12 1294 1434 NA NA NA NA NA NA NA 36143 FUN_016250 140 35 15 208 200 NA NA NA NA NA NA NA 36144 FUN_016251 378 75 7 632 695 NA NA NA NA NA NA NA 36145 FUN_003171 0 0 0 8 0 NA NA NA NA NA NA NA 36146 FUN_003170 6 1 1 1 0 NA NA NA NA NA NA NA 36147 FUN_003173 0 0 0 21 16 NA NA NA NA NA NA NA 36148 FUN_003172 0 0 0 10 0 NA NA NA NA NA NA NA 36149 FUN_003174 1 7 6 24 10 NA NA NA NA NA NA NA 36150 FUN_003178 170 43 0 0 9 NA NA NA NA NA NA NA 36151 FUN_028064 80 206 148 154 139 NA NA NA NA NA NA NA 36152 FUN_028065 0 31 19 12 49 NA NA NA NA NA NA NA 36153 FUN_028066 146 260 142 69 61 NA NA NA NA NA NA NA 36154 FUN_028060 0 16 0 0 20 NA NA NA NA NA NA NA 36155 FUN_028061 0 0 0 0 35 NA NA NA NA NA NA NA 36156 FUN_036869 0 0 5 0 37 NA NA NA NA NA NA NA 36157 FUN_028063 427 586 95 101 184 NA NA NA NA NA NA NA 36158 FUN_036867 42 46 51 85 116 NA NA NA NA NA NA NA 36159 FUN_036866 22 6 2 56 30 NA NA NA NA NA NA NA 36160 FUN_036865 87 65 129 212 100 NA NA NA NA NA NA NA 36161 FUN_028068 16 11 21 10 3 NA NA NA NA NA NA NA 36162 FUN_028069 142 125 102 39 65 NA NA NA NA NA NA NA 36163 FUN_004255 124 63 81 164 124 NA NA NA NA NA NA NA 36164 FUN_042798 6 11 21 6 112 NA NA NA NA NA NA NA 36165 FUN_042799 8 0 24 3 224 NA NA NA NA NA NA NA 36166 FUN_042792 170 386 367 374 1044 NA NA NA NA NA NA NA 36167 FUN_042793 42 32 55 9 345 NA NA NA NA NA NA NA 36168 FUN_042790 13 11 41 17 296 NA NA NA NA NA NA NA 36169 FUN_042791 0 0 15 4 15 NA NA NA NA NA NA NA 36170 FUN_042796 23 42 43 47 145 NA NA NA NA NA NA NA 36171 FUN_042797 157 313 333 303 856 NA NA NA NA NA NA NA 36172 FUN_042794 177 374 365 349 989 NA NA NA NA NA NA NA 36173 FUN_042795 41 28 60 13 351 NA NA NA NA NA NA NA 36174 FUN_010940 4139 4065 2665 4168 4438 ptg000007l:4568021-4597427 Q4QR58 3.24e-23 Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) Xenopus laevis (African clawed frog) formation of cytoplasmic translation initiation complex [GO:0001732]; translational initiation [GO:0006413] GO:0001732; GO:0003723; GO:0003743; GO:0005852; GO:0006413; GO:0016282; GO:0031369; GO:0033290 36175 FUN_010941 3051 4259 2244 4849 4235 ptg000007l:4600883-4609697 D3ZSZ3 4.07e-21 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; serine phosphorylation of STAT protein [GO:0042501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0000287; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0007179; GO:0016055; GO:0018107; GO:0030178; GO:0031625; GO:0035556; GO:0042169; GO:0042501; GO:0046777; GO:0050821; GO:0106310; GO:0140297 36176 FUN_010941 3051 4259 2244 4849 4235 ptg000007l:4600883-4609697 D3ZSZ3 4.07e-21 Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) Rattus norvegicus (Rat) intracellular signal transduction [GO:0035556]; negative regulation of Wnt signaling pathway [GO:0030178]; peptidyl-threonine phosphorylation [GO:0018107]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; serine phosphorylation of STAT protein [GO:0042501]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0000287; GO:0004672; GO:0004674; GO:0004707; GO:0005524; GO:0005634; GO:0005737; GO:0006355; GO:0006468; GO:0007179; GO:0016055; GO:0018107; GO:0030178; GO:0031625; GO:0035556; GO:0042169; GO:0042501; GO:0046777; GO:0050821; GO:0106310; GO:0140297 36177 FUN_010942 1298 1086 667 1845 1241 NA NA NA NA NA NA NA 36178 FUN_010943 146 191 61 335 184 NA NA NA NA NA NA NA 36179 FUN_010944 91 324 83 885 272 NA NA NA NA NA NA NA 36180 FUN_010945 15280 11058 6373 16855 12561 NA NA NA NA NA NA NA 36181 FUN_010946 8832 9109 4696 15241 4134 NA NA NA NA NA NA NA 36182 FUN_043778 2325 2859 2364 2772 1317 NA NA NA NA NA NA NA 36183 FUN_010949 386 98 223 61 360 NA NA NA NA NA NA NA 36184 FUN_043775 52 0 36 0 13 NA NA NA NA NA NA NA 36185 FUN_043774 78 162 211 181 46 NA NA NA NA NA NA NA 36186 FUN_043773 174 66 117 114 79 NA NA NA NA NA NA NA 36187 FUN_043771 66 91 52 217 37 NA NA NA NA NA NA NA 36188 FUN_042428 17 0 29 0 92 ptg000036l:4841453-4841765 Q8MTV8 3.54e-47 Histone H4 Aplysia californica (California sea hare) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36189 FUN_042429 0 0 27 0 8 NA NA NA NA NA NA NA 36190 FUN_042424 1987 1985 1256 2122 1650 ptg000036l:4777092-4782883 P0CP97 1.52e-27 FK506-binding protein 2 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) (Filobasidiella neoformans) chaperone-mediated protein folding [GO:0061077]; protein peptidyl-prolyl isomerization [GO:0000413] GO:0000413; GO:0003755; GO:0005783; GO:0061077 36191 FUN_042425 921 906 2430 404 513 NA NA NA NA NA NA NA 36192 FUN_042426 483 230 393 201 294 NA NA NA NA NA NA NA 36193 FUN_042420 0 0 0 0 17 NA NA NA NA NA NA NA 36194 FUN_042421 0 0 0 0 28 NA NA NA NA NA NA NA 36195 FUN_042423 0 0 0 14 0 NA NA NA NA NA NA NA 36196 FUN_041681 785 832 883 1307 1093 NA NA NA NA NA NA NA 36197 FUN_041680 148 107 158 248 219 NA NA NA NA NA NA NA 36198 FUN_041683 31 115 39 62 161 NA NA NA NA NA NA NA 36199 FUN_041682 988 1148 562 1386 1661 NA NA NA NA NA NA NA 36200 FUN_041685 156 103 50 153 58 NA NA NA NA NA NA NA 36201 FUN_041684 124 69 47 205 61 NA NA NA NA NA NA NA 36202 FUN_041687 190 29 94 185 165 NA NA NA NA NA NA NA 36203 FUN_041686 294 90 101 157 185 NA NA NA NA NA NA NA 36204 FUN_041689 0 0 0 0 28 ptg000035l:6559779-6560775 Q5QD04 4.13e-23 Trace amine-associated receptor 9 (TaR-9) (Trace amine receptor 9) (mTaar9) Mus musculus (Mouse) NA GO:0001594; GO:0005886 36205 FUN_041688 212 204 240 321 257 NA NA NA NA NA NA NA 36206 FUN_028514 139 972 1750 549 499 NA NA NA NA NA NA NA 36207 FUN_022749 43 20 22 30 26 ptg000016l:12714870-12715756 P25291 1.44e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 36208 FUN_022748 44 18 28 18 21 ptg000016l:12713754-12714637 P25291 1.23e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 36209 FUN_009148 19 7 0 3 12 NA NA NA NA NA NA NA 36210 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 1.82e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36211 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 1.6e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36212 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 2.07e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36213 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 8.23e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36214 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 1.46e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36215 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 3.15e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36216 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 5.5e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36217 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 5.49e-55 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36218 FUN_009149 228 828 28 167 1154 ptg000004l:3235836-3241120 Q96AY4 5.3e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36219 FUN_009147 0 37 1 0 75 NA NA NA NA NA NA NA 36220 FUN_022741 32 6 15 7 20 ptg000016l:12704815-12705701 P25291 5.28e-28 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 36221 FUN_009145 19 62 50 37 37 NA NA NA NA NA NA NA 36222 FUN_022747 52 15 27 18 19 ptg000016l:12712635-12713521 P25291 1.07e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 36223 FUN_009140 59 139 69 87 37 ptg000004l:3167294-3171137 Q96AY4 7.16e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36224 FUN_009140 59 139 69 87 37 ptg000004l:3167294-3171137 Q96AY4 1.72e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36225 FUN_009140 59 139 69 87 37 ptg000004l:3167294-3171137 Q96AY4 3.26e-106 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36226 FUN_009140 59 139 69 87 37 ptg000004l:3167294-3171137 Q96AY4 5.65e-92 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36227 FUN_009140 59 139 69 87 37 ptg000004l:3167294-3171137 Q96AY4 4.06e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36228 FUN_022744 49 15 28 21 29 ptg000016l:12708168-12709054 P25291 1.07e-27 Pancreatic secretory granule membrane major glycoprotein GP2 (Pancreatic zymogen granule membrane protein GP-2) (ZAP75) Canis lupus familiaris (Dog) (Canis familiaris) antigen transcytosis by M cells in mucosal-associated lymphoid tissue [GO:0002412]; innate immune response [GO:0045087]; neutrophil migration [GO:1990266] GO:0002412; GO:0005201; GO:0005615; GO:0005768; GO:0009897; GO:0009986; GO:0016324; GO:0042589; GO:0045087; GO:0045121; GO:1990266 36229 FUN_011409 65 4 57 14 251 NA NA NA NA NA NA NA 36230 FUN_011403 0 0 11 0 0 NA NA NA NA NA NA NA 36231 FUN_007067 1265 771 967 1148 586 NA NA NA NA NA NA NA 36232 FUN_011400 0 0 0 0 11 NA NA NA NA NA NA NA 36233 FUN_007066 4020 2548 2324 3879 2838 NA NA NA NA NA NA NA 36234 FUN_043121 779 204 445 238 517 ptg000047l:4337676-4344305 Q9ULJ7 1.36e-48 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 36235 FUN_040488 790 202 329 444 198 NA NA NA NA NA NA NA 36236 FUN_040489 1674 1644 1306 1739 2423 NA NA NA NA NA NA NA 36237 FUN_040485 649 152 192 170 179 NA NA NA NA NA NA NA 36238 FUN_040486 1125 965 1071 933 38 NA NA NA NA NA NA NA 36239 FUN_040487 320 54 215 2555 172 NA NA NA NA NA NA NA 36240 FUN_040482 1680 384 127 331 212 NA NA NA NA NA NA NA 36241 FUN_040483 0 0 0 29 0 NA NA NA NA NA NA NA 36242 FUN_006806 82 79 88 89 217 NA NA NA NA NA NA NA 36243 FUN_043125 418 200 101 268 228 NA NA NA NA NA NA NA 36244 FUN_007069 485 317 209 349 276 NA NA NA NA NA NA NA 36245 FUN_007068 1720 1880 1105 1685 1266 NA NA NA NA NA NA NA 36246 FUN_040157 35 0 57 20 327 NA NA NA NA NA NA NA 36247 FUN_040154 2829 845 1062 2909 1958 NA NA NA NA NA NA NA 36248 FUN_040155 0 0 10 20 53 NA NA NA NA NA NA NA 36249 FUN_040152 34016 28182 15066 18328 18150 NA NA NA NA NA NA NA 36250 FUN_040153 1093 671 748 747 678 NA NA NA NA NA NA NA 36251 FUN_040150 2196 1472 1209 2627 1543 NA NA NA NA NA NA NA 36252 FUN_040151 1306 644 347 359 337 NA NA NA NA NA NA NA 36253 FUN_040158 57 34 10 77 61 NA NA NA NA NA NA NA 36254 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36255 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36256 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36257 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36258 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36259 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36260 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36261 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36262 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36263 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36264 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36265 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36266 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.89e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36267 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36268 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36269 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36270 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36271 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36272 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36273 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36274 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36275 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36276 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36277 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36278 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36279 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.19e-83 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36280 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36281 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36282 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36283 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36284 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36285 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36286 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36287 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36288 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36289 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36290 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.07e-79 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36291 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36292 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36293 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36294 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36295 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36296 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36297 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36298 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36299 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36300 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36301 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36302 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36303 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.31e-73 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36304 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36305 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36306 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36307 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36308 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36309 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36310 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36311 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36312 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36313 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36314 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36315 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.27e-72 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36316 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36317 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36318 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36319 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36320 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36321 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36322 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36323 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36324 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36325 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36326 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.18e-71 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36327 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36328 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36329 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36330 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36331 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36332 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36333 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36334 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36335 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36336 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 6.99e-68 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36337 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36338 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36339 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36340 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36341 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36342 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36343 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36344 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36345 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36346 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36347 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 4.99e-66 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36348 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36349 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36350 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36351 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36352 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36353 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36354 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36355 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36356 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 7.17e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36357 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36358 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36359 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36360 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36361 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36362 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36363 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36364 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.6e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36365 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36366 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36367 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36368 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36369 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36370 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36371 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36372 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36373 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.09e-50 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36374 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36375 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36376 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36377 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36378 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36379 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36380 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36381 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.15e-49 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36382 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36383 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36384 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36385 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36386 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36387 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36388 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36389 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 8.12e-46 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36390 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.39e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36391 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.39e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36392 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.39e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36393 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.39e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36394 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.39e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36395 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.39e-43 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36396 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36397 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36398 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36399 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36400 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36401 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36402 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36403 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.53e-42 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36404 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.8e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36405 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.8e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36406 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.8e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36407 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.8e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36408 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.8e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36409 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36410 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36411 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36412 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36413 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36414 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36415 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 1.72e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36416 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36417 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36418 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36419 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36420 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36421 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.25e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36422 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.66e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36423 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.66e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36424 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.66e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36425 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 3.66e-23 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36426 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.27e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36427 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.27e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36428 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.27e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36429 FUN_040159 0 0 0 0 9 ptg000031l:4898704-4908074 P10079 2.27e-21 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 36430 FUN_006804 302 163 139 321 198 ptg000001l:16846052-16851560 Q5ZKY0 3.04e-57 Endosomal/lysosomal proton channel TMEM175 (Transmembrane protein 175) Gallus gallus (Chicken) lysosomal lumen pH elevation [GO:0035752]; neuron cellular homeostasis [GO:0070050]; phagosome-lysosome fusion [GO:0090385]; potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of lysosomal lumen pH [GO:0035751] GO:0005267; GO:0005764; GO:0005765; GO:0005768; GO:0010008; GO:0015252; GO:0022841; GO:0035751; GO:0035752; GO:0050544; GO:0070050; GO:0071805; GO:0090385; GO:1902600 36431 FUN_006804 302 163 139 321 198 ptg000001l:16846052-16851560 Q5ZKY0 7.31e-37 Endosomal/lysosomal proton channel TMEM175 (Transmembrane protein 175) Gallus gallus (Chicken) lysosomal lumen pH elevation [GO:0035752]; neuron cellular homeostasis [GO:0070050]; phagosome-lysosome fusion [GO:0090385]; potassium ion transmembrane transport [GO:0071805]; proton transmembrane transport [GO:1902600]; regulation of lysosomal lumen pH [GO:0035751] GO:0005267; GO:0005764; GO:0005765; GO:0005768; GO:0010008; GO:0015252; GO:0022841; GO:0035751; GO:0035752; GO:0050544; GO:0070050; GO:0071805; GO:0090385; GO:1902600 36432 FUN_015239 1310 2413 1695 1266 1426 NA NA NA NA NA NA NA 36433 FUN_015238 2680 3974 740 1767 1067 NA NA NA NA NA NA NA 36434 FUN_015235 1322 1067 561 552 884 NA NA NA NA NA NA NA 36435 FUN_015234 0 0 0 2 28 NA NA NA NA NA NA NA 36436 FUN_015237 710 377 201 607 248 ptg000009l:7800853-7802482 Q494W8 2.74e-49 CHRNA7-FAM7A fusion protein (CHRNA7-DR1) (D-10) Homo sapiens (Human) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165]; synaptic transmission, cholinergic [GO:0007271] GO:0004888; GO:0005231; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0007271; GO:0022848; GO:0030594; GO:0034220; GO:0042166; GO:0042391; GO:0043005; GO:0045202; GO:0050877; GO:0098794; GO:1904315 36437 FUN_015236 214 94 83 154 85 ptg000009l:7776590-7781984 P48180 1.15e-49 Acetylcholine receptor subunit alpha-type acr-16 Caenorhabditis elegans chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005886; GO:0007165; GO:0007268; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0042995; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:1904315 36438 FUN_015231 234 916 44 255 224 NA NA NA NA NA NA NA 36439 FUN_015230 590 418 68 493 465 ptg000009l:7703072-7704569 A7RFA1 3.92e-96 Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein) Nematostella vectensis (Starlet sea anemone) catabolic process [GO:0009056] GO:0008270; GO:0009056; GO:0016787 36440 FUN_015230 590 418 68 493 465 ptg000009l:7703072-7704569 A7RFA1 2.09e-49 Phosphotriesterase-related protein (EC 3.1.-.-) (Parathion hydrolase-related protein) Nematostella vectensis (Starlet sea anemone) catabolic process [GO:0009056] GO:0008270; GO:0009056; GO:0016787 36441 FUN_015233 1765 2309 978 2077 1340 ptg000009l:7737763-7740566 Q11126 1.28e-22 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 36442 FUN_015232 232 252 153 261 48 ptg000009l:7721458-7723635 Q9I8C7 9e-52 Neuronal acetylcholine receptor subunit alpha-10 (Alpha 10 nAChR) (Nicotinic acetylcholine receptor subunit alpha-10) (NACHR alpha-10) Gallus gallus (Chicken) chemical synaptic transmission [GO:0007268]; ion transmembrane transport [GO:0034220]; membrane depolarization [GO:0051899]; nervous system process [GO:0050877]; regulation of membrane potential [GO:0042391]; response to auditory stimulus [GO:0010996]; signal transduction [GO:0007165] GO:0004888; GO:0005231; GO:0005262; GO:0005886; GO:0005892; GO:0007165; GO:0007268; GO:0010996; GO:0022848; GO:0030594; GO:0034220; GO:0042391; GO:0043005; GO:0045202; GO:0045211; GO:0050877; GO:0051899; GO:1904315 36443 FUN_024370 180 144 147 230 311 ptg000018l:5496498-5498049 Q02040 3.53e-107 A-kinase anchor protein 17A (AKAP-17A) (721P) (B-lymphocyte antigen) (Protein XE7) (Protein kinase A-anchoring protein 17A) (PRKA17A) (Splicing factor, arginine/serine-rich 17A) Homo sapiens (Human) B cell activation [GO:0042113]; mRNA processing [GO:0006397]; regulation of DNA-templated transcription [GO:0006355]; regulation of RNA splicing [GO:0043484]; RNA splicing [GO:0008380]; signal transduction [GO:0007165] GO:0003723; GO:0005634; GO:0005681; GO:0005829; GO:0006355; GO:0006397; GO:0007165; GO:0008380; GO:0016607; GO:0042113; GO:0043484; GO:0051018 36444 FUN_024371 1724 1994 862 1226 896 ptg000018l:5500614-5502884 Q5XIU9 5.02e-22 Membrane-associated progesterone receptor component 2 Rattus norvegicus (Rat) adipose tissue development [GO:0060612]; heme transport [GO:0015886] GO:0005496; GO:0005635; GO:0005783; GO:0012505; GO:0015232; GO:0015886; GO:0016020; GO:0020037; GO:0060612 36445 FUN_024372 1073 1197 570 1188 720 NA NA NA NA NA NA NA 36446 FUN_032419 157 81 24 28 32 NA NA NA NA NA NA NA 36447 FUN_024374 191 33 49 95 188 NA NA NA NA NA NA NA 36448 FUN_024375 3725 5201 1826 3291 2174 NA NA NA NA NA NA NA 36449 FUN_024376 39878 52186 18862 33345 19829 ptg000018l:5541328-5545067 P62909 7.74e-37 40S ribosomal protein S3 (EC 4.2.99.18) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; negative regulation of DNA repair [GO:0045738]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of translation [GO:0017148]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of base-excision repair [GO:1905053]; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001272]; positive regulation of DNA N-glycosylase activity [GO:1902546]; positive regulation of DNA repair [GO:0045739]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of T cell receptor signaling pathway [GO:0050862]; regulation of apoptotic process [GO:0042981]; response to TNF agonist [GO:0061481]; spindle assembly [GO:0051225]; translation [GO:0006412] GO:0003677; GO:0003684; GO:0003723; GO:0003729; GO:0003735; GO:0003906; GO:0004520; GO:0005634; GO:0005730; GO:0005737; GO:0005743; GO:0005759; GO:0005829; GO:0005840; GO:0005844; GO:0005886; GO:0006281; GO:0006412; GO:0006915; GO:0006974; GO:0007059; GO:0008017; GO:0010628; GO:0012505; GO:0014069; GO:0015631; GO:0017148; GO:0019899; GO:0019900; GO:0019901; GO:0022626; GO:0022627; GO:0030425; GO:0030544; GO:0031116; GO:0031334; GO:0031397; GO:0032079; GO:0032357; GO:0032358; GO:0032587; GO:0032743; GO:0034614; GO:0042104; GO:0042981; GO:0043507; GO:0044390; GO:0044877; GO:0045202; GO:0045738; GO:0045739; GO:0050862; GO:0051018; GO:0051092; GO:0051225; GO:0051301; GO:0051879; GO:0061481; GO:0070181; GO:0070301; GO:0071159; GO:0071356; GO:0072686; GO:0097100; GO:0140078; GO:0140297; GO:1901224; GO:1902231; GO:1902546; GO:1905053; GO:1990090; GO:1990904; GO:2001235; GO:2001272 36450 FUN_024376 39878 52186 18862 33345 19829 ptg000018l:5541328-5545067 P62909 2.05e-32 40S ribosomal protein S3 (EC 4.2.99.18) Rattus norvegicus (Rat) apoptotic process [GO:0006915]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to reactive oxygen species [GO:0034614]; cellular response to tumor necrosis factor [GO:0071356]; chromosome segregation [GO:0007059]; DNA repair [GO:0006281]; negative regulation of DNA repair [GO:0045738]; negative regulation of protein ubiquitination [GO:0031397]; negative regulation of translation [GO:0017148]; positive regulation of activated T cell proliferation [GO:0042104]; positive regulation of apoptotic signaling pathway [GO:2001235]; positive regulation of base-excision repair [GO:1905053]; positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [GO:2001272]; positive regulation of DNA N-glycosylase activity [GO:1902546]; positive regulation of DNA repair [GO:0045739]; positive regulation of endodeoxyribonuclease activity [GO:0032079]; positive regulation of gene expression [GO:0010628]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage [GO:1902231]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of microtubule polymerization [GO:0031116]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein-containing complex assembly [GO:0031334]; positive regulation of T cell receptor signaling pathway [GO:0050862]; regulation of apoptotic process [GO:0042981]; response to TNF agonist [GO:0061481]; spindle assembly [GO:0051225]; translation [GO:0006412] GO:0003677; GO:0003684; GO:0003723; GO:0003729; GO:0003735; GO:0003906; GO:0004520; GO:0005634; GO:0005730; GO:0005737; GO:0005743; GO:0005759; GO:0005829; GO:0005840; GO:0005844; GO:0005886; GO:0006281; GO:0006412; GO:0006915; GO:0006974; GO:0007059; GO:0008017; GO:0010628; GO:0012505; GO:0014069; GO:0015631; GO:0017148; GO:0019899; GO:0019900; GO:0019901; GO:0022626; GO:0022627; GO:0030425; GO:0030544; GO:0031116; GO:0031334; GO:0031397; GO:0032079; GO:0032357; GO:0032358; GO:0032587; GO:0032743; GO:0034614; GO:0042104; GO:0042981; GO:0043507; GO:0044390; GO:0044877; GO:0045202; GO:0045738; GO:0045739; GO:0050862; GO:0051018; GO:0051092; GO:0051225; GO:0051301; GO:0051879; GO:0061481; GO:0070181; GO:0070301; GO:0071159; GO:0071356; GO:0072686; GO:0097100; GO:0140078; GO:0140297; GO:1901224; GO:1902231; GO:1902546; GO:1905053; GO:1990090; GO:1990904; GO:2001235; GO:2001272 36451 FUN_024377 2943 2485 2943 2513 2088 NA NA NA NA NA NA NA 36452 FUN_024378 740 336 672 725 469 ptg000018l:5548678-5552066 P43793 4.43e-175 NADP-specific glutamate dehydrogenase (NADP-GDH) (EC 1.4.1.4) Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) glutamate biosynthetic process [GO:0006537] GO:0004354; GO:0005737; GO:0005829; GO:0006537 36453 FUN_032410 0 75 66 25 6 ptg000023l:31648099-31651337 Q6DIV6 4.36e-38 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 36454 FUN_032411 0 0 17 10 28 NA NA NA NA NA NA NA 36455 FUN_032416 15 21 0 5 4 ptg000023l:31728921-31733107 Q6PF45 4.67e-46 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (xVIAAT) Xenopus laevis (African clawed frog) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 36456 FUN_032417 0 0 0 0 15 NA NA NA NA NA NA NA 36457 FUN_032414 84 145 40 80 101 ptg000023l:31690499-31691789 Q6DIV6 4.66e-50 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 36458 FUN_032415 0 21 0 19 0 ptg000023l:31696903-31727124 Q6DIV6 1.19e-36 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 36459 FUN_038450 0 0 27 50 7 NA NA NA NA NA NA NA 36460 FUN_038451 26 0 265 397 71 NA NA NA NA NA NA NA 36461 FUN_038452 221 119 66 275 95 NA NA NA NA NA NA NA 36462 FUN_038454 1284 278 253 598 297 NA NA NA NA NA NA NA 36463 FUN_038455 348 111 95 239 145 NA NA NA NA NA NA NA 36464 FUN_038456 756 635 507 812 1035 NA NA NA NA NA NA NA 36465 FUN_038457 1442 1307 1022 1291 850 NA NA NA NA NA NA NA 36466 FUN_038458 85 38 50 13 70 NA NA NA NA NA NA NA 36467 FUN_038459 1261 4221 503 1384 1319 NA NA NA NA NA NA NA 36468 FUN_028806 77 74 22 40 13 ptg000022l:4282326-4286334 Q96AY4 3.73e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36469 FUN_028806 77 74 22 40 13 ptg000022l:4282326-4286334 Q96AY4 2.08e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36470 FUN_028806 77 74 22 40 13 ptg000022l:4282326-4286334 Q96AY4 1.77e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36471 FUN_028806 77 74 22 40 13 ptg000022l:4282326-4286334 Q96AY4 6.65e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36472 FUN_028806 77 74 22 40 13 ptg000022l:4282326-4286334 Q96AY4 7.18e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36473 FUN_028807 59 33 69 25 12 ptg000022l:4299156-4304062 Q96AY4 2.7e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36474 FUN_028807 59 33 69 25 12 ptg000022l:4299156-4304062 Q96AY4 1.58e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36475 FUN_028807 59 33 69 25 12 ptg000022l:4299156-4304062 Q96AY4 4.16e-135 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36476 FUN_028807 59 33 69 25 12 ptg000022l:4299156-4304062 Q96AY4 9.29e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36477 FUN_028807 59 33 69 25 12 ptg000022l:4299156-4304062 Q96AY4 1.55e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36478 FUN_028804 71 60 11 32 14 ptg000022l:4248407-4252415 Q96AY4 3.73e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36479 FUN_028804 71 60 11 32 14 ptg000022l:4248407-4252415 Q96AY4 2.08e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36480 FUN_028804 71 60 11 32 14 ptg000022l:4248407-4252415 Q96AY4 1.77e-126 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36481 FUN_028804 71 60 11 32 14 ptg000022l:4248407-4252415 Q96AY4 6.65e-68 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36482 FUN_028804 71 60 11 32 14 ptg000022l:4248407-4252415 Q96AY4 7.18e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36483 FUN_028805 48 31 40 19 9 ptg000022l:4265235-4270141 Q96AY4 1.79e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36484 FUN_028805 48 31 40 19 9 ptg000022l:4265235-4270141 Q96AY4 2.64e-139 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36485 FUN_028805 48 31 40 19 9 ptg000022l:4265235-4270141 Q96AY4 1.67e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36486 FUN_028805 48 31 40 19 9 ptg000022l:4265235-4270141 Q96AY4 9.22e-120 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36487 FUN_028805 48 31 40 19 9 ptg000022l:4265235-4270141 Q96AY4 1.96e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36488 FUN_028802 0 0 21 0 0 NA NA NA NA NA NA NA 36489 FUN_028803 1822 960 1563 2136 1436 ptg000022l:4159153-4241185 Q96AY4 2.74e-161 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36490 FUN_028803 1822 960 1563 2136 1436 ptg000022l:4159153-4241185 Q96AY4 3.95e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36491 FUN_028803 1822 960 1563 2136 1436 ptg000022l:4159153-4241185 Q96AY4 8.39e-52 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36492 FUN_028803 1822 960 1563 2136 1436 ptg000022l:4159153-4241185 Q96AY4 6.31e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36493 FUN_028803 1822 960 1563 2136 1436 ptg000022l:4159153-4241185 Q96AY4 2.94e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36494 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 1.24e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36495 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 9.6e-164 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36496 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 6.57e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36497 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 6.28e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36498 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 1.24e-136 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36499 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 6.83e-128 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36500 FUN_028808 40 17 37 62 46 ptg000022l:4317672-4323897 Q96AY4 1.58e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36501 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 2.68e-87 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36502 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 1.02e-78 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36503 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 1.33e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36504 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 4.28e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36505 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 3.04e-66 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36506 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 3.61e-46 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36507 FUN_028809 12 14 26 0 3 ptg000022l:4339540-4342753 Q96AY4 9.09e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36508 FUN_013993 0 0 0 0 57 NA NA NA NA NA NA NA 36509 FUN_013997 0 0 0 2 88 NA NA NA NA NA NA NA 36510 FUN_013994 0 0 0 0 19 NA NA NA NA NA NA NA 36511 FUN_011434 3 0 5 156 32 NA NA NA NA NA NA NA 36512 FUN_001320 1804 579 421 730 7 NA NA NA NA NA NA NA 36513 FUN_001321 11 0 0 6 0 NA NA NA NA NA NA NA 36514 FUN_001328 6125 3977 2739 4562 4254 NA NA NA NA NA NA NA 36515 FUN_001329 1498 1436 911 1471 1584 NA NA NA NA NA NA NA 36516 FUN_015907 0 0 0 0 6 NA NA NA NA NA NA NA 36517 FUN_015906 131 0 36 9 0 NA NA NA NA NA NA NA 36518 FUN_015909 5 20 33 18 70 NA NA NA NA NA NA NA 36519 FUN_015908 0 0 0 0 8 NA NA NA NA NA NA NA 36520 FUN_039321 221 68 85 276 168 NA NA NA NA NA NA NA 36521 FUN_039320 57 18 43 0 0 NA NA NA NA NA NA NA 36522 FUN_039323 1097 185 147 508 383 ptg000028l:616810-618037 Q11126 2.44e-42 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (FUTB) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) Bos taurus (Bovine) fucosylation [GO:0036065]; lipid metabolic process [GO:0006629]; oligosaccharide metabolic process [GO:0009311]; positive regulation of cell-cell adhesion [GO:0022409]; protein N-linked glycosylation [GO:0006487]; protein O-linked glycosylation [GO:0006493]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127] GO:0006487; GO:0006493; GO:0006629; GO:0009311; GO:0017060; GO:0017083; GO:0022409; GO:0030334; GO:0032580; GO:0036065; GO:0042127; GO:0046920 36523 FUN_039322 282 215 188 403 387 ptg000028l:602607-612656 A9Z1V5 6.93e-67 von Willebrand factor A domain-containing protein 5B1 Mus musculus (Mouse) NA GO:0005576 36524 FUN_039325 21 0 0 115 0 NA NA NA NA NA NA NA 36525 FUN_039324 392 0 13 210 2 ptg000029c:2548-4434 Q7RTR2 9.05e-60 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36526 FUN_039324 392 0 13 210 2 ptg000029c:2548-4434 Q7RTR2 2.61e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36527 FUN_039324 392 0 13 210 2 ptg000029c:2548-4434 Q7RTR2 1.06e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36528 FUN_039324 392 0 13 210 2 ptg000029c:2548-4434 Q7RTR2 1.22e-49 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36529 FUN_039324 392 0 13 210 2 ptg000029c:2548-4434 Q7RTR2 4.01e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36530 FUN_039327 0 0 0 12 0 NA NA NA NA NA NA NA 36531 FUN_039326 0 0 0 37 0 NA NA NA NA NA NA NA 36532 FUN_037728 8 35 0 11 0 ptg000026l:12848784-12853352 Q9UHC6 9.43e-36 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 36533 FUN_027051 0 4 0 0 34 NA NA NA NA NA NA NA 36534 FUN_027052 0 0 20 0 0 NA NA NA NA NA NA NA 36535 FUN_027053 0 0 0 0 15 NA NA NA NA NA NA NA 36536 FUN_027055 248 134 0 138 202 NA NA NA NA NA NA NA 36537 FUN_027056 6 0 0 4 0 NA NA NA NA NA NA NA 36538 FUN_027058 9 0 25 13 78 NA NA NA NA NA NA NA 36539 FUN_023867 472 200 123 645 352 NA NA NA NA NA NA NA 36540 FUN_028961 185 237 142 387 324 NA NA NA NA NA NA NA 36541 FUN_017215 20 0 8 0 36 NA NA NA NA NA NA NA 36542 FUN_017214 4 0 269 0 0 NA NA NA NA NA NA NA 36543 FUN_017217 61 0 119 0 58 NA NA NA NA NA NA NA 36544 FUN_017216 0 0 0 0 21 NA NA NA NA NA NA NA 36545 FUN_017210 0 0 0 0 45 NA NA NA NA NA NA NA 36546 FUN_017218 0 0 7 0 0 NA NA NA NA NA NA NA 36547 FUN_005007 179 160 174 253 262 NA NA NA NA NA NA NA 36548 FUN_000074 4 0 4 1 7 ntLink_4:65494-69132 P35061 7.39e-76 Histone H2A Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36549 FUN_000077 6 0 11 2 20 ntLink_4:74347-75110 P84239 1.46e-91 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36550 FUN_000076 2 0 6 1 9 ntLink_4:72820-74081 P35067 1.67e-80 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36551 FUN_000071 1 0 8 0 18 ntLink_4:59573-60354 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36552 FUN_000070 3 0 4 0 11 ntLink_4:55877-58450 P84239 5.05e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36553 FUN_000073 2 0 5 0 16 ntLink_4:63639-64420 P84239 5.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 36554 FUN_040058 3670 3116 1730 3474 2492 NA NA NA NA NA NA NA 36555 FUN_027946 540 169 156 301 305 NA NA NA NA NA NA NA 36556 FUN_027947 1275 952 552 818 787 ptg000021l:13707972-13708452 Q0VD26 2.76e-43 MORN repeat-containing protein 4 (Retinophilin) Bos taurus (Bovine) response to axon injury [GO:0048678] GO:0005737; GO:0032426; GO:0032433; GO:0042995; GO:0048678 36557 FUN_027944 114 59 10 80 40 ptg000021l:13617159-13693050 P0CT40 5.13e-79 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 36558 FUN_027945 17 29 61 12 84 NA NA NA NA NA NA NA 36559 FUN_027943 30 78 18 162 14 NA NA NA NA NA NA NA 36560 FUN_027940 393 515 657 350 720 NA NA NA NA NA NA NA 36561 FUN_027941 438 749 534 1089 447 ptg000021l:13557782-13589493 P0CT40 6.13e-71 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 36562 FUN_027941 438 749 534 1089 447 ptg000021l:13557782-13589493 P0CT40 6.13e-71 Transposon Tf2-9 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0005737; GO:0006310; GO:0006508; GO:0015074; GO:0046872 36563 FUN_027948 2612 12 6 1902 0 ptg000021l:13714157-13715126 Q63HM9 8.47e-62 PI-PLC X domain-containing protein 3 Homo sapiens (Human) lipid catabolic process [GO:0016042]; signal transduction [GO:0007165] GO:0005737; GO:0007165; GO:0008081; GO:0016042; GO:0045202 36564 FUN_026099 577 972 99 1264 299 NA NA NA NA NA NA NA 36565 FUN_014749 805 700 149 1299 1238 NA NA NA NA NA NA NA 36566 FUN_026093 1094 615 564 896 751 NA NA NA NA NA NA NA 36567 FUN_014743 822 331 365 473 481 NA NA NA NA NA NA NA 36568 FUN_026091 10600 6187 2128 7656 1987 NA NA NA NA NA NA NA 36569 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 5.99e-62 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36570 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 3.26e-61 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36571 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 1.1e-60 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36572 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 1.15e-60 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36573 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 3.72e-60 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36574 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 4e-60 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36575 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 5.68e-60 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36576 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 7.26e-59 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36577 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 3.21e-58 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36578 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 1.06e-57 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36579 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 6.1e-57 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36580 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 1.6e-54 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36581 FUN_026090 1664 643 1059 1699 1094 ptg000020l:4521228-4542734 Q03650 6.87e-53 Cysteine-rich, acidic integral membrane protein Trypanosoma brucei brucei endocytosis [GO:0006897] GO:0005886; GO:0006897; GO:0020016 36582 FUN_026097 464 174 291 324 169 ptg000020l:4596644-4599996 A1DWM3 2.35e-23 Major facilitator superfamily domain-containing protein 6 (Macrophage MHC class I receptor 2 homolog) Sus scrofa (Pig) antigen processing and presentation of exogenous peptide antigen via MHC class I [GO:0042590] GO:0005886; GO:0016020; GO:0042590 36583 FUN_026096 2098 2002 979 2254 1491 ptg000020l:4587083-4589687 P19891 2.21e-122 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) cellular response to glucose starvation [GO:0042149]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]; negative regulation of apoptotic process [GO:0043066]; positive regulation of mitotic cell cycle [GO:0045931] GO:0004066; GO:0005524; GO:0005829; GO:0006541; GO:0042149; GO:0043066; GO:0045931; GO:0070981 36584 FUN_026096 2098 2002 979 2254 1491 ptg000020l:4587083-4589687 P19891 6.95e-84 Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Glutamine-dependent asparagine synthetase) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) cellular response to glucose starvation [GO:0042149]; glutamine metabolic process [GO:0006541]; L-asparagine biosynthetic process [GO:0070981]; negative regulation of apoptotic process [GO:0043066]; positive regulation of mitotic cell cycle [GO:0045931] GO:0004066; GO:0005524; GO:0005829; GO:0006541; GO:0042149; GO:0043066; GO:0045931; GO:0070981 36585 FUN_026095 12 0 0 0 0 NA NA NA NA NA NA NA 36586 FUN_014745 0 2 0 0 29 NA NA NA NA NA NA NA 36587 FUN_040051 19 207 27 91 142 NA NA NA NA NA NA NA 36588 FUN_025549 898 1204 98 163 1411 NA NA NA NA NA NA NA 36589 FUN_025540 7992 10066 5021 2768 3082 NA NA NA NA NA NA NA 36590 FUN_025541 8050 7778 4764 6540 2522 NA NA NA NA NA NA NA 36591 FUN_025542 835 292 215 801 619 NA NA NA NA NA NA NA 36592 FUN_025543 104 95 32 112 85 NA NA NA NA NA NA NA 36593 FUN_025544 3253 1643 1471 2923 1963 NA NA NA NA NA NA NA 36594 FUN_025545 9 14 12 0 15 NA NA NA NA NA NA NA 36595 FUN_025546 115 23 20 20 66 NA NA NA NA NA NA NA 36596 FUN_024639 124 45 55 26 61 NA NA NA NA NA NA NA 36597 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 5.58e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36598 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 1.37e-25 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36599 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 4.44e-24 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36600 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 2.92e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36601 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 5.55e-23 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36602 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 1.86e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36603 FUN_024638 35 0 33 30 0 ptg000018l:9278921-9287458 Q7RTR2 5.29e-22 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36604 FUN_024631 216 95 145 146 421 NA NA NA NA NA NA NA 36605 FUN_024630 548 508 467 655 574 NA NA NA NA NA NA NA 36606 FUN_024633 534 298 139 284 424 NA NA NA NA NA NA NA 36607 FUN_024632 2524 2451 930 3151 2388 ptg000018l:9228128-9241819 P36602 5.93e-51 Ribonucleoside-diphosphate reductase large chain (EC 1.17.4.1) (Ribonucleotide reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) CDP metabolic process [GO:0046704]; dCDP biosynthetic process [GO:0006240]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; dTTP biosynthetic process [GO:0006235] GO:0004748; GO:0005524; GO:0005737; GO:0005829; GO:0005971; GO:0006235; GO:0006240; GO:0006260; GO:0009263; GO:0046704 36608 FUN_024632 2524 2451 930 3151 2388 ptg000018l:9228128-9241819 P36602 1.18e-26 Ribonucleoside-diphosphate reductase large chain (EC 1.17.4.1) (Ribonucleotide reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) CDP metabolic process [GO:0046704]; dCDP biosynthetic process [GO:0006240]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; dTTP biosynthetic process [GO:0006235] GO:0004748; GO:0005524; GO:0005737; GO:0005829; GO:0005971; GO:0006235; GO:0006240; GO:0006260; GO:0009263; GO:0046704 36609 FUN_024632 2524 2451 930 3151 2388 ptg000018l:9228128-9241819 P36602 1.18e-26 Ribonucleoside-diphosphate reductase large chain (EC 1.17.4.1) (Ribonucleotide reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) CDP metabolic process [GO:0046704]; dCDP biosynthetic process [GO:0006240]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; dTTP biosynthetic process [GO:0006235] GO:0004748; GO:0005524; GO:0005737; GO:0005829; GO:0005971; GO:0006235; GO:0006240; GO:0006260; GO:0009263; GO:0046704 36610 FUN_024632 2524 2451 930 3151 2388 ptg000018l:9228128-9241819 P36602 9.71e-22 Ribonucleoside-diphosphate reductase large chain (EC 1.17.4.1) (Ribonucleotide reductase) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) CDP metabolic process [GO:0046704]; dCDP biosynthetic process [GO:0006240]; deoxyribonucleotide biosynthetic process [GO:0009263]; DNA replication [GO:0006260]; dTTP biosynthetic process [GO:0006235] GO:0004748; GO:0005524; GO:0005737; GO:0005829; GO:0005971; GO:0006235; GO:0006240; GO:0006260; GO:0009263; GO:0046704 36611 FUN_024635 3 6 0 12 4 NA NA NA NA NA NA NA 36612 FUN_024634 17 66 9 45 79 NA NA NA NA NA NA NA 36613 FUN_024637 15 25 0 22 24 NA NA NA NA NA NA NA 36614 FUN_024636 130 290 44 115 269 NA NA NA NA NA NA NA 36615 FUN_021041 0 0 8 115 5 NA NA NA NA NA NA NA 36616 FUN_021040 9 7 2 7 11 NA NA NA NA NA NA NA 36617 FUN_021043 42 6 20 16 36 NA NA NA NA NA NA NA 36618 FUN_021042 4 8 2 132 13 NA NA NA NA NA NA NA 36619 FUN_021045 0 8 0 27 1 NA NA NA NA NA NA NA 36620 FUN_021044 0 0 8 77 0 NA NA NA NA NA NA NA 36621 FUN_021046 149 347 478 1477 105 NA NA NA NA NA NA NA 36622 FUN_040057 220 147 342 944 907 NA NA NA NA NA NA NA 36623 FUN_004481 2924 1712 1859 4494 3414 NA NA NA NA NA NA NA 36624 FUN_040054 2893 2321 1374 2097 1718 NA NA NA NA NA NA NA 36625 FUN_038159 186 116 58 82 122 NA NA NA NA NA NA NA 36626 FUN_038158 316 183 72 185 112 NA NA NA NA NA NA NA 36627 FUN_006286 1062 1510 1135 276 364 ptg000001l:10182580-10216452 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 36628 FUN_006286 1062 1510 1135 276 364 ptg000001l:10182580-10216452 O15050 1.75e-40 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 36629 FUN_006286 1062 1510 1135 276 364 ptg000001l:10182580-10216452 O15050 1.29e-26 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 36630 FUN_006287 4460 1954 3017 4969 4335 ptg000001l:10226351-10255112 O15050 0 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 36631 FUN_006287 4460 1954 3017 4969 4335 ptg000001l:10226351-10255112 O15050 2.02e-30 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 36632 FUN_006287 4460 1954 3017 4969 4335 ptg000001l:10226351-10255112 O15050 6.13e-21 TPR and ankyrin repeat-containing protein 1 (Lupus brain antigen 1 homolog) Homo sapiens (Human) NA NA 36633 FUN_038153 655 600 304 848 741 NA NA NA NA NA NA NA 36634 FUN_038152 2835 2429 1086 2062 1502 ptg000027l:3116799-3120181 P07283 7.53e-22 Phosphomannomutase (PMM) (EC 5.4.2.8) (Asparagine-linked glycosylation protein 4) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GDP-mannose biosynthetic process [GO:0009298]; mannose metabolic process [GO:0006013]; protein N-linked glycosylation [GO:0006487] GO:0004615; GO:0005829; GO:0006013; GO:0006487; GO:0009298; GO:0010494; GO:0046872 36635 FUN_038155 137 63 50 44 36 NA NA NA NA NA NA NA 36636 FUN_038157 4 17 2 0 14 NA NA NA NA NA NA NA 36637 FUN_038156 63 541 174 146 127 NA NA NA NA NA NA NA 36638 FUN_028847 1349 717 826 1217 1127 NA NA NA NA NA NA NA 36639 FUN_035682 2735 3419 1588 1365 2241 ptg000025l:10595506-10605168 Q8BJT9 1.93e-24 ER degradation-enhancing alpha-mannosidase-like protein 2 Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; endoplasmic reticulum mannose trimming [GO:1904380]; mannose trimming involved in glycoprotein ERAD pathway [GO:1904382]; positive regulation of retrograde protein transport, ER to cytosol [GO:1904154]; response to unfolded protein [GO:0006986]; trimming of terminal mannose on B branch [GO:0036509]; ubiquitin-dependent glycoprotein ERAD pathway [GO:0097466] GO:0004571; GO:0005509; GO:0005783; GO:0005788; GO:0005975; GO:0006986; GO:0016020; GO:0036509; GO:0044322; GO:0097466; GO:1904154; GO:1904380; GO:1904382 36640 FUN_035683 2882 2707 1698 3027 2328 NA NA NA NA NA NA NA 36641 FUN_035680 867 152 158 172 72 NA NA NA NA NA NA NA 36642 FUN_035681 195 82 100 153 180 NA NA NA NA NA NA NA 36643 FUN_035686 0 0 0 14 0 NA NA NA NA NA NA NA 36644 FUN_035687 0 0 0 287 0 NA NA NA NA NA NA NA 36645 FUN_035684 950 1308 442 707 1185 NA NA NA NA NA NA NA 36646 FUN_035685 14 41 0 0 12 NA NA NA NA NA NA NA 36647 FUN_035688 1132 1442 734 833 830 NA NA NA NA NA NA NA 36648 FUN_035689 2638 1512 1375 2215 1644 ptg000025l:10671116-10677231 Q99L88 1.14e-60 Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (Syntrophin-2) Mus musculus (Mouse) NA GO:0003779; GO:0005198; GO:0005516; GO:0005737; GO:0005856; GO:0016010; GO:0030165; GO:0032991; GO:0042383; GO:0045202; GO:0070161 36649 FUN_001883 5833 8783 3193 5323 4521 NA NA NA NA NA NA NA 36650 FUN_001882 8168 20327 12660 14251 10364 NA NA NA NA NA NA NA 36651 FUN_001881 109 1490 667 129 1439 ntLink_6:17306162-17309642 Q80XJ3 3.25e-43 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 36652 FUN_001881 109 1490 667 129 1439 ntLink_6:17306162-17309642 Q80XJ3 4.31e-38 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 36653 FUN_001881 109 1490 667 129 1439 ntLink_6:17306162-17309642 Q80XJ3 5.1e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 36654 FUN_001881 109 1490 667 129 1439 ntLink_6:17306162-17309642 Q80XJ3 8.26e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 36655 FUN_001880 0 3 18 0 10 NA NA NA NA NA NA NA 36656 FUN_001887 278 245 223 211 375 NA NA NA NA NA NA NA 36657 FUN_001886 0 293 142 0 281 NA NA NA NA NA NA NA 36658 FUN_001885 56 0 0 0 48 NA NA NA NA NA NA NA 36659 FUN_001884 16 46 15 148 73 ntLink_6:17335613-17343051 P21328 1.25e-40 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) NA GO:0003964 36660 FUN_001888 216 127 123 126 230 NA NA NA NA NA NA NA 36661 FUN_020026 0 0 0 14 18 NA NA NA NA NA NA NA 36662 FUN_020027 4 1 2 2 56 NA NA NA NA NA NA NA 36663 FUN_036089 1137 517 332 904 539 NA NA NA NA NA NA NA 36664 FUN_036088 9 44 0 29 13 NA NA NA NA NA NA NA 36665 FUN_036081 381 236 285 682 495 NA NA NA NA NA NA NA 36666 FUN_036080 3451 1502 986 1822 792 NA NA NA NA NA NA NA 36667 FUN_036083 1843 1549 920 1293 999 NA NA NA NA NA NA NA 36668 FUN_036082 2586 2284 1111 1532 1324 NA NA NA NA NA NA NA 36669 FUN_036085 2215 2512 1530 2149 1894 NA NA NA NA NA NA NA 36670 FUN_036084 1477 1109 1006 2156 1543 NA NA NA NA NA NA NA 36671 FUN_036087 86 114 45 53 121 NA NA NA NA NA NA NA 36672 FUN_036086 26 75 32 38 39 NA NA NA NA NA NA NA 36673 FUN_001775 109 114 72 112 51 NA NA NA NA NA NA NA 36674 FUN_001777 1048 818 1231 1233 1053 NA NA NA NA NA NA NA 36675 FUN_001776 728 623 413 932 656 NA NA NA NA NA NA NA 36676 FUN_001771 6711 5856 3870 3981 1623 ntLink_6:15872620-15884246 Q7ZVA0 1.98e-37 WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0000398; GO:0005634; GO:0005737; GO:0008380; GO:0016607; GO:0071005; GO:0071011 36677 FUN_001771 6711 5856 3870 3981 1623 ntLink_6:15872620-15884246 Q7ZVA0 1.79e-22 WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA splicing, via spliceosome [GO:0000398]; regulation of alternative mRNA splicing, via spliceosome [GO:0000381]; RNA splicing [GO:0008380] GO:0000381; GO:0000398; GO:0005634; GO:0005737; GO:0008380; GO:0016607; GO:0071005; GO:0071011 36678 FUN_001770 2283 2316 1916 1425 1277 NA NA NA NA NA NA NA 36679 FUN_001773 20 22 29 38 25 NA NA NA NA NA NA NA 36680 FUN_001772 1056 645 525 938 523 NA NA NA NA NA NA NA 36681 FUN_001779 350 140 193 508 545 NA NA NA NA NA NA NA 36682 FUN_001778 999 447 579 1109 969 NA NA NA NA NA NA NA 36683 FUN_037932 1814 1500 547 1679 1015 ptg000027l:642904-644626 F4KFT7 1.13e-22 Bifunctional TH2 protein, mitochondrial (THIAMINE REQUIRING 2) [Includes: Thiamine phosphate phosphatase (EC 3.1.3.100); Aminopyrimidine aminohydrolase (EC 3.5.99.2)] Arabidopsis thaliana (Mouse-ear cress) thiamine biosynthetic process [GO:0009228] GO:0005739; GO:0005829; GO:0009228; GO:0042131; GO:0050334 36684 FUN_037933 1107 328 489 583 633 NA NA NA NA NA NA NA 36685 FUN_037930 1307 340 571 866 770 ptg000027l:630693-637045 Q5ZIE8 3.84e-23 Activating transcription factor 7-interacting protein 1 (MBD1-containing chromatin-associated factor 1) Gallus gallus (Chicken) positive regulation of DNA methylation-dependent heterochromatin formation [GO:0090309]; protein stabilization [GO:0050821]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein stability [GO:0031647] GO:0003712; GO:0005634; GO:0005667; GO:0006355; GO:0031647; GO:0050821; GO:0090309 36686 FUN_037931 433 953 506 373 492 ptg000027l:638848-642027 A7M7B9 1.69e-32 Endonuclease III-like protein 1 (EC 3.2.2.-) (EC 4.2.99.18) (Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase) (DNA glycosylase/AP lyase) Gallus gallus (Chicken) base-excision repair, AP site formation [GO:0006285]; nucleotide-excision repair, DNA incision, 5'-to lesion [GO:0006296] GO:0000703; GO:0003677; GO:0003906; GO:0005634; GO:0005739; GO:0006285; GO:0006296; GO:0046872; GO:0051539; GO:0140078 36687 FUN_037936 6031 11179 2766 6329 4063 ptg000027l:668746-670681 Q28DT9 8.86e-35 SPRY domain-containing SOCS box protein 3 (SSB-3) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) protein ubiquitination [GO:0016567] GO:0016567 36688 FUN_037937 4775 7092 2723 7605 5260 ptg000027l:671805-677744 Q5M9B1 2.27e-45 SPRY domain-containing SOCS box protein 3 (SSB-3) Xenopus laevis (African clawed frog) protein ubiquitination [GO:0016567] GO:0016567 36689 FUN_037934 298 119 109 111 110 NA NA NA NA NA NA NA 36690 FUN_037935 201 104 196 83 126 NA NA NA NA NA NA NA 36691 FUN_037938 4343 2327 1988 2490 1468 NA NA NA NA NA NA NA 36692 FUN_037939 0 18 35 50 29 ptg000027l:701018-702709 P41340 0 Actin-3 (EC 3.6.4.-) Limulus polyphemus (Atlantic horseshoe crab) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 36693 FUN_037939 0 18 35 50 29 ptg000027l:701018-702709 P41340 4.55e-75 Actin-3 (EC 3.6.4.-) Limulus polyphemus (Atlantic horseshoe crab) NA GO:0005524; GO:0005737; GO:0005856; GO:0016787 36694 FUN_005252 36 7 3 25 15 NA NA NA NA NA NA NA 36695 FUN_005253 318 161 113 276 185 NA NA NA NA NA NA NA 36696 FUN_005250 0 0 0 0 22 NA NA NA NA NA NA NA 36697 FUN_005251 5647 4486 2859 6034 3362 ntLink_8:33164346-33174388 A2VDZ3 9.1e-33 Myocyte-specific enhancer factor 2A Bos taurus (Bovine) apoptotic process [GO:0006915]; cardiac conduction [GO:0061337]; cellular response to calcium ion [GO:0071277]; dendrite morphogenesis [GO:0048813]; ERK5 cascade [GO:0070375]; MAPK cascade [GO:0000165]; mitochondrial genome maintenance [GO:0000002]; mitochondrion distribution [GO:0048311]; negative regulation of transcription by RNA polymerase II [GO:0000122]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357]; ventricular cardiac myofibril assembly [GO:0055005] GO:0000002; GO:0000122; GO:0000165; GO:0000977; GO:0000978; GO:0000981; GO:0003682; GO:0005634; GO:0006357; GO:0006915; GO:0035035; GO:0042826; GO:0045944; GO:0046332; GO:0046983; GO:0048311; GO:0048813; GO:0055005; GO:0061337; GO:0070375; GO:0071277; GO:0140297 36698 FUN_005257 0 0 27 0 51 NA NA NA NA NA NA NA 36699 FUN_005254 92 90 67 69 92 NA NA NA NA NA NA NA 36700 FUN_005255 294 204 194 256 231 NA NA NA NA NA NA NA 36701 FUN_005258 12406 9271 6091 7149 4809 NA NA NA NA NA NA NA 36702 FUN_005259 434 344 121 170 115 NA NA NA NA NA NA NA 36703 FUN_018305 873 390 805 603 175 NA NA NA NA NA NA NA 36704 FUN_036337 773 527 314 742 943 NA NA NA NA NA NA NA 36705 FUN_036336 754 632 392 926 1161 NA NA NA NA NA NA NA 36706 FUN_036335 583 433 223 564 788 NA NA NA NA NA NA NA 36707 FUN_036334 1958 2833 851 2239 871 NA NA NA NA NA NA NA 36708 FUN_036338 19184 23745 9072 14416 5140 ptg000025l:17856578-17858665 Q6GL74 2.45e-34 Cilia- and flagella-associated protein 20 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; positive regulation of cell motility [GO:2000147]; positive regulation of feeding behavior [GO:2000253]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296] GO:0005634; GO:0005814; GO:0005879; GO:0005929; GO:0018095; GO:0036064; GO:0060271; GO:0060296; GO:2000147; GO:2000253 36709 FUN_036338 19184 23745 9072 14416 5140 ptg000025l:17856578-17858665 Q6GL74 2.45e-34 Cilia- and flagella-associated protein 20 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) cilium assembly [GO:0060271]; positive regulation of cell motility [GO:2000147]; positive regulation of feeding behavior [GO:2000253]; protein polyglutamylation [GO:0018095]; regulation of cilium beat frequency involved in ciliary motility [GO:0060296] GO:0005634; GO:0005814; GO:0005879; GO:0005929; GO:0018095; GO:0036064; GO:0060271; GO:0060296; GO:2000147; GO:2000253 36710 FUN_027558 160 10 17 0 24 NA NA NA NA NA NA NA 36711 FUN_037686 5047 3601 2917 4167 3743 NA NA NA NA NA NA NA 36712 FUN_037687 3283 6804 1801 2340 1792 NA NA NA NA NA NA NA 36713 FUN_037680 74 0 120 147 230 NA NA NA NA NA NA NA 36714 FUN_037681 235 159 152 176 106 NA NA NA NA NA NA NA 36715 FUN_037682 122 145 54 68 22 NA NA NA NA NA NA NA 36716 FUN_037683 121 15 39 67 47 NA NA NA NA NA NA NA 36717 FUN_027550 33 1 16 16 10 NA NA NA NA NA NA NA 36718 FUN_027553 8 0 0 4 26 NA NA NA NA NA NA NA 36719 FUN_027552 12 14 4 15 8 NA NA NA NA NA NA NA 36720 FUN_037688 1448 1016 841 958 852 NA NA NA NA NA NA NA 36721 FUN_027554 0 0 24 0 0 NA NA NA NA NA NA NA 36722 FUN_033309 793 1191 480 588 541 NA NA NA NA NA NA NA 36723 FUN_033308 291 113 70 123 171 NA NA NA NA NA NA NA 36724 FUN_008207 7 1 0 31 20 NA NA NA NA NA NA NA 36725 FUN_033301 0 0 0 37 12 NA NA NA NA NA NA NA 36726 FUN_033300 50 37 78 71 91 NA NA NA NA NA NA NA 36727 FUN_033302 51 77 60 5 345 NA NA NA NA NA NA NA 36728 FUN_006661 196 27 425 132 162 NA NA NA NA NA NA NA 36729 FUN_008202 877 362 549 637 1052 NA NA NA NA NA NA NA 36730 FUN_008203 2282 1503 1116 2171 1841 NA NA NA NA NA NA NA 36731 FUN_006664 0 14 0 472 368 NA NA NA NA NA NA NA 36732 FUN_006665 6 14 1 17 15 NA NA NA NA NA NA NA 36733 FUN_016878 29 39 42 66 130 NA NA NA NA NA NA NA 36734 FUN_016879 2 0 17 0 23 NA NA NA NA NA NA NA 36735 FUN_016876 2949 679 928 423 194 NA NA NA NA NA NA NA 36736 FUN_016877 1616 3219 1765 1189 1038 NA NA NA NA NA NA NA 36737 FUN_016874 0 10 0 0 15 NA NA NA NA NA NA NA 36738 FUN_016875 621 428 262 213 359 NA NA NA NA NA NA NA 36739 FUN_016872 18 0 0 0 52 NA NA NA NA NA NA NA 36740 FUN_016870 463 445 265 743 374 NA NA NA NA NA NA NA 36741 FUN_016871 0 0 3 2 15 NA NA NA NA NA NA NA 36742 FUN_006961 16 0 1 3 150 NA NA NA NA NA NA NA 36743 FUN_016442 3 0 17 0 77 NA NA NA NA NA NA NA 36744 FUN_016441 55 0 112 30 112 NA NA NA NA NA NA NA 36745 FUN_006962 275 188 33 126 341 NA NA NA NA NA NA NA 36746 FUN_006964 96 8 21 25 231 NA NA NA NA NA NA NA 36747 FUN_006503 157 619 60 691 665 NA NA NA NA NA NA NA 36748 FUN_006502 14 7 0 0 34 NA NA NA NA NA NA NA 36749 FUN_008565 261 49 199 367 324 NA NA NA NA NA NA NA 36750 FUN_006500 213 992 613 684 926 NA NA NA NA NA NA NA 36751 FUN_008563 0 18 0 0 8 NA NA NA NA NA NA NA 36752 FUN_006967 32 20 0 0 0 NA NA NA NA NA NA NA 36753 FUN_006505 0 164 0 529 127 NA NA NA NA NA NA NA 36754 FUN_006504 166 39 23 148 78 NA NA NA NA NA NA NA 36755 FUN_006508 753 1779 885 1370 1474 NA NA NA NA NA NA NA 36756 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 1.38e-91 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36757 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 5.08e-80 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36758 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 1.35e-77 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36759 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 4.09e-75 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36760 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 1.86e-71 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36761 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 1.79e-59 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36762 FUN_008569 11 77 0 85 25 ptg000002l:12972313-12975557 O70511 3.69e-41 Ankyrin-3 (ANK-3) (Ankyrin-G) Rattus norvegicus (Rat) anterograde axonal transport [GO:0008089]; axon development [GO:0061564]; axon guidance [GO:0007411]; axonogenesis [GO:0007409]; cellular response to magnesium ion [GO:0071286]; clustering of voltage-gated sodium channels [GO:0045162]; establishment of protein localization [GO:0045184]; establishment or maintenance of microtubule cytoskeleton polarity [GO:0030951]; Golgi to plasma membrane protein transport [GO:0043001]; magnesium ion homeostasis [GO:0010960]; maintenance of protein location in cell [GO:0032507]; maintenance of protein location in plasma membrane [GO:0072660]; membrane assembly [GO:0071709]; mitotic cytokinesis [GO:0000281]; negative regulation of delayed rectifier potassium channel activity [GO:1902260]; negative regulation of endocytosis [GO:0045806]; neuromuscular junction development [GO:0007528]; neuronal action potential [GO:0019228]; plasma membrane organization [GO:0007009]; positive regulation of cation channel activity [GO:2001259]; positive regulation of cell communication by electrical coupling [GO:0010650]; positive regulation of gene expression [GO:0010628]; positive regulation of homotypic cell-cell adhesion [GO:0034112]; positive regulation of membrane depolarization during cardiac muscle cell action potential [GO:1900827]; positive regulation of membrane potential [GO:0045838]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of sodium ion transmembrane transporter activity [GO:2000651]; positive regulation of sodium ion transport [GO:0010765]; protein localization to axon [GO:0099612]; protein localization to plasma membrane [GO:0072659]; regulation of potassium ion transport [GO:0043266]; regulation of protein targeting [GO:1903533]; response to immobilization stress [GO:0035902]; signal transduction [GO:0007165]; synapse organization [GO:0050808] GO:0000281; GO:0005200; GO:0005737; GO:0005764; GO:0005856; GO:0005886; GO:0007009; GO:0007165; GO:0007409; GO:0007411; GO:0007528; GO:0008089; GO:0008092; GO:0009925; GO:0009986; GO:0010628; GO:0010650; GO:0010765; GO:0010960; GO:0014704; GO:0014731; GO:0016020; GO:0016323; GO:0016328; GO:0016529; GO:0019228; GO:0030018; GO:0030315; GO:0030424; GO:0030425; GO:0030507; GO:0030674; GO:0030951; GO:0031594; GO:0032507; GO:0033268; GO:0033270; GO:0034112; GO:0035902; GO:0042383; GO:0043001; GO:0043005; GO:0043034; GO:0043194; GO:0043266; GO:0044325; GO:0045162; GO:0045184; GO:0045202; GO:0045211; GO:0045296; GO:0045806; GO:0045838; GO:0050808; GO:0061564; GO:0071286; GO:0071709; GO:0072659; GO:0072660; GO:0090314; GO:0099612; GO:0140031; GO:1900827; GO:1901224; GO:1902260; GO:1903533; GO:1904115; GO:2000651; GO:2001259 36763 FUN_008568 0 0 2 26 29 NA NA NA NA NA NA NA 36764 FUN_040017 817 117 264 637 850 ptg000031l:3015205-3021580 Q7Z3E1 1.45e-34 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) (TCDD-inducible poly [ADP-ribose] polymerase) Homo sapiens (Human) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 36765 FUN_004617 7 2 0 0 0 NA NA NA NA NA NA NA 36766 FUN_040014 0 36 0 20 7 NA NA NA NA NA NA NA 36767 FUN_040013 59 24 19 163 13 NA NA NA NA NA NA NA 36768 FUN_004610 0 0 7 0 22 NA NA NA NA NA NA NA 36769 FUN_040011 7 40 2 43 52 NA NA NA NA NA NA NA 36770 FUN_004619 149 136 132 188 109 NA NA NA NA NA NA NA 36771 FUN_004618 451 277 234 351 172 NA NA NA NA NA NA NA 36772 FUN_040018 523 296 100 86 222 ptg000031l:3027030-3033570 Q8C1B2 6.16e-28 Protein mono-ADP-ribosyltransferase TIPARP (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (TCDD-inducible poly [ADP-ribose] polymerase) Mus musculus (Mouse) androgen metabolic process [GO:0008209]; cellular response to organic cyclic compound [GO:0071407]; estrogen metabolic process [GO:0008210]; face morphogenesis [GO:0060325]; female gonad development [GO:0008585]; hemopoiesis [GO:0030097]; kidney development [GO:0001822]; negative regulation of gene expression [GO:0010629]; nitrogen compound metabolic process [GO:0006807]; platelet-derived growth factor receptor signaling pathway [GO:0048008]; positive regulation of protein catabolic process [GO:0045732]; post-embryonic development [GO:0009791]; roof of mouth development [GO:0060021]; skeletal system morphogenesis [GO:0048705]; smooth muscle tissue development [GO:0048745]; vasculogenesis [GO:0001570] GO:0000987; GO:0001570; GO:0001822; GO:0003950; GO:0005634; GO:0006807; GO:0008209; GO:0008210; GO:0008585; GO:0009791; GO:0010629; GO:0016779; GO:0030097; GO:0045732; GO:0046872; GO:0048008; GO:0048705; GO:0048745; GO:0060021; GO:0060325; GO:0071407; GO:0140803; GO:1990404 36773 FUN_034652 0 0 0 0 20 NA NA NA NA NA NA NA 36774 FUN_034651 0 0 0 13 0 NA NA NA NA NA NA NA 36775 FUN_034656 36 77 67 10 285 NA NA NA NA NA NA NA 36776 FUN_034657 0 0 0 0 23 NA NA NA NA NA NA NA 36777 FUN_034659 8 0 0 0 0 NA NA NA NA NA NA NA 36778 FUN_013304 11 0 9 16 23 NA NA NA NA NA NA NA 36779 FUN_003526 11 10 6 64 41 NA NA NA NA NA NA NA 36780 FUN_028398 0 16 0 47 141 NA NA NA NA NA NA NA 36781 FUN_028399 0 23 0 190 235 NA NA NA NA NA NA NA 36782 FUN_028396 4 2 51 0 106 NA NA NA NA NA NA NA 36783 FUN_028397 0 0 0 3 26 NA NA NA NA NA NA NA 36784 FUN_028394 0 1540 9 525 444 NA NA NA NA NA NA NA 36785 FUN_028395 0 33 176 80 31 NA NA NA NA NA NA NA 36786 FUN_028392 17 56 65 27 27 NA NA NA NA NA NA NA 36787 FUN_028390 0 0 0 0 31 NA NA NA NA NA NA NA 36788 FUN_028391 187 77 141 245 79 NA NA NA NA NA NA NA 36789 FUN_004754 1664 1107 950 1624 1617 NA NA NA NA NA NA NA 36790 FUN_040310 0 52 0 0 0 NA NA NA NA NA NA NA 36791 FUN_004755 233 1633 460 538 698 NA NA NA NA NA NA NA 36792 FUN_010234 0 2 3 41 16 NA NA NA NA NA NA NA 36793 FUN_039569 23 0 14 0 79 NA NA NA NA NA NA NA 36794 FUN_010233 0 17 7 0 2 NA NA NA NA NA NA NA 36795 FUN_041942 2380 1366 1381 3054 2377 NA NA NA NA NA NA NA 36796 FUN_041943 844 520 429 1085 608 ptg000035l:9146945-9155023 Q96MT7 3.78e-46 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 36797 FUN_041943 844 520 429 1085 608 ptg000035l:9146945-9155023 Q96MT7 3.78e-46 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 36798 FUN_041943 844 520 429 1085 608 ptg000035l:9146945-9155023 Q96MT7 9.03e-28 Cilia- and flagella-associated protein 44 (WD repeat-containing protein 52) Homo sapiens (Human) cilium assembly [GO:0060271]; cilium-dependent cell motility [GO:0060285]; microtubule cytoskeleton organization [GO:0000226]; sperm axoneme assembly [GO:0007288] GO:0000226; GO:0005737; GO:0005856; GO:0007288; GO:0008233; GO:0031514; GO:0060271; GO:0060285 36799 FUN_041940 349 227 129 275 317 NA NA NA NA NA NA NA 36800 FUN_031757 1206 212 387 822 822 NA NA NA NA NA NA NA 36801 FUN_041946 585 243 302 394 215 NA NA NA NA NA NA NA 36802 FUN_041947 3647 2100 1508 1174 2544 NA NA NA NA NA NA NA 36803 FUN_041944 108467 93141 45942 66521 38886 NA NA NA NA NA NA NA 36804 FUN_041945 2241 1124 1162 1954 1490 NA NA NA NA NA NA NA 36805 FUN_041949 70 156 0 0 24 NA NA NA NA NA NA NA 36806 FUN_002519 396 0 0 24 0 NA NA NA NA NA NA NA 36807 FUN_002513 179 308 101 530 16 NA NA NA NA NA NA NA 36808 FUN_002514 0 0 18 0 0 NA NA NA NA NA NA NA 36809 FUN_002515 988 101 306 626 343 NA NA NA NA NA NA NA 36810 FUN_002516 239 171 76 242 24 NA NA NA NA NA NA NA 36811 FUN_002517 186 98 3 395 2 NA NA NA NA NA NA NA 36812 FUN_011064 804 918 427 883 985 NA NA NA NA NA NA NA 36813 FUN_011065 51 0 0 12 23 NA NA NA NA NA NA NA 36814 FUN_011066 493 295 185 321 560 NA NA NA NA NA NA NA 36815 FUN_011067 656 369 349 386 192 NA NA NA NA NA NA NA 36816 FUN_011060 0 0 0 8 17 NA NA NA NA NA NA NA 36817 FUN_011062 0 13 0 0 0 NA NA NA NA NA NA NA 36818 FUN_011063 0 0 0 11 5 NA NA NA NA NA NA NA 36819 FUN_031758 5638 4601 44 198 2180 NA NA NA NA NA NA NA 36820 FUN_011068 3451 3594 3379 8625 4989 NA NA NA NA NA NA NA 36821 FUN_011069 0 0 0 5 38 NA NA NA NA NA NA NA 36822 FUN_039566 188 0 0 103 0 NA NA NA NA NA NA NA 36823 FUN_018746 13 0 0 90 9 NA NA NA NA NA NA NA 36824 FUN_017931 807 393 606 2683 1169 NA NA NA NA NA NA NA 36825 FUN_017932 11374 10068 5600 10891 8799 NA NA NA NA NA NA NA 36826 FUN_018745 57 21 13 185 61 ptg000012l:12816099-12821012 Q9Y6N7 5.21e-21 Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1) Homo sapiens (Human) activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; aorta development [GO:0035904]; aortic valve morphogenesis [GO:0003180]; axon midline choice point recognition [GO:0016199]; cell adhesion [GO:0007155]; cell migration involved in sprouting angiogenesis [GO:0002042]; chemorepulsion involved in postnatal olfactory bulb interneuron migration [GO:0021836]; endocardial cushion formation [GO:0003272]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; negative regulation of cell migration [GO:0030336]; negative regulation of chemokine-mediated signaling pathway [GO:0070100]; negative regulation of gene expression [GO:0010629]; negative regulation of mammary gland epithelial cell proliferation [GO:0033600]; negative regulation of negative chemotaxis [GO:0050925]; nervous system development [GO:0007399]; outflow tract septum morphogenesis [GO:0003148]; positive regulation of axonogenesis [GO:0050772]; positive regulation of gene expression [GO:0010628]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of Notch signaling pathway involved in heart induction [GO:0035481]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of vascular endothelial growth factor signaling pathway [GO:1900748]; pulmonary valve morphogenesis [GO:0003184]; Roundabout signaling pathway [GO:0035385]; ventricular septum morphogenesis [GO:0060412] GO:0002042; GO:0003148; GO:0003180; GO:0003184; GO:0003272; GO:0005737; GO:0005886; GO:0006919; GO:0007155; GO:0007156; GO:0007399; GO:0008046; GO:0009986; GO:0010628; GO:0010629; GO:0016199; GO:0021836; GO:0030275; GO:0030336; GO:0030424; GO:0033116; GO:0033600; GO:0035025; GO:0035385; GO:0035481; GO:0035904; GO:0042802; GO:0043406; GO:0050772; GO:0050925; GO:0060412; GO:0070100; GO:1900748 36827 FUN_018742 73 19 85 248 76 NA NA NA NA NA NA NA 36828 FUN_018743 11 0 28 0 22 NA NA NA NA NA NA NA 36829 FUN_017936 685 444 280 713 492 ptg000012l:2109662-2113059 Q1LXR6 2.24e-82 NA NA NA NA 36830 FUN_017936 685 444 280 713 492 ptg000012l:2109662-2113059 Q1LXR6 1.24e-54 NA NA NA NA 36831 FUN_043098 681 348 296 571 774 NA NA NA NA NA NA NA 36832 FUN_043099 1578 740 646 1052 1506 NA NA NA NA NA NA NA 36833 FUN_043096 0 0 0 0 25 NA NA NA NA NA NA NA 36834 FUN_043097 2991 2018 884 5621 3145 NA NA NA NA NA NA NA 36835 FUN_043094 1178 334 601 1147 860 NA NA NA NA NA NA NA 36836 FUN_018741 148 39 30 736 756 NA NA NA NA NA NA NA 36837 FUN_043092 4221 1896 2228 3369 3213 NA NA NA NA NA NA NA 36838 FUN_043090 30 78 52 77 91 NA NA NA NA NA NA NA 36839 FUN_043091 1508 1200 870 1075 1318 NA NA NA NA NA NA NA 36840 FUN_000611 830 60 215 136 83 NA NA NA NA NA NA NA 36841 FUN_029270 809 578 593 1207 1036 NA NA NA NA NA NA NA 36842 FUN_029271 0 7 25 25 13 ptg000022l:9788899-9791275 P06603 0 Tubulin alpha-1 chain (EC 3.6.5.-) Drosophila melanogaster (Fruit fly) lysosome localization [GO:0032418]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000235; GO:0000278; GO:0005200; GO:0005525; GO:0005634; GO:0005737; GO:0005813; GO:0005819; GO:0005874; GO:0016787; GO:0032418; GO:0046872; GO:0048471 36843 FUN_000615 177 46 89 152 104 ntLink_6:5070572-5072799 Q5ZLL7 4.26e-21 WD repeat-containing protein 91 Gallus gallus (Chicken) early endosome to late endosome transport [GO:0045022]; regulation of phosphatidylinositol 3-kinase activity [GO:0043551] GO:0005829; GO:0031313; GO:0031901; GO:0031902; GO:0035014; GO:0043551; GO:0045022 36844 FUN_029277 16077 9798 4769 10227 6822 ptg000022l:9906203-9908043 Q63340 5.58e-25 Dual specificity protein phosphatase 7 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase MKP-X) Rattus norvegicus (Rat) negative regulation of MAP kinase activity [GO:0043407]; negative regulation of MAPK cascade [GO:0043409]; peptidyl-tyrosine dephosphorylation [GO:0035335] GO:0004721; GO:0004725; GO:0005737; GO:0005829; GO:0008330; GO:0017017; GO:0017018; GO:0035335; GO:0043407; GO:0043409 36845 FUN_000617 168 79 130 95 94 ntLink_6:5087325-5133470 Q9CZR2 1.94e-101 N-acetylated-alpha-linked acidic dipeptidase 2 (EC 3.4.17.21) (Glutamate carboxypeptidase III) (GCPIII) (N-acetylaspartylglutamate peptidase II) (NAAG-peptidase II) (N-acetylated-alpha-linked acidic dipeptidase II) (NAALADase II) Mus musculus (Mouse) neurotransmitter catabolic process [GO:0042135]; proteolysis [GO:0006508] GO:0004180; GO:0004181; GO:0005886; GO:0006508; GO:0008233; GO:0016020; GO:0016805; GO:0042135; GO:0046872; GO:0050129 36846 FUN_000616 2002 1120 750 1331 705 ntLink_6:5073128-5076291 P54186 8.4e-24 Protein D1 Onchocerca volvulus NA NA 36847 FUN_000619 16 1059 17 4091 10 NA NA NA NA NA NA NA 36848 FUN_000618 1715 1375 659 1115 1365 NA NA NA NA NA NA NA 36849 FUN_029278 45 37 12 26 20 NA NA NA NA NA NA NA 36850 FUN_029279 307 189 184 124 34 NA NA NA NA NA NA NA 36851 FUN_014857 1515 1505 631 801 1086 NA NA NA NA NA NA NA 36852 FUN_016595 88 226 178 15 34 NA NA NA NA NA NA NA 36853 FUN_016594 37 127 102 55 12 NA NA NA NA NA NA NA 36854 FUN_016597 2 0 6 19 55 NA NA NA NA NA NA NA 36855 FUN_016596 3182 1678 1765 2711 3404 NA NA NA NA NA NA NA 36856 FUN_016591 4191 3390 2645 1446 1694 NA NA NA NA NA NA NA 36857 FUN_016590 11225 4381 4807 4931 2304 NA NA NA NA NA NA NA 36858 FUN_013518 12 87 152 14 37 NA NA NA NA NA NA NA 36859 FUN_016592 2131 1506 999 1503 1052 NA NA NA NA NA NA NA 36860 FUN_013516 35 299 24 48 394 NA NA NA NA NA NA NA 36861 FUN_013517 391 1668 1260 1640 97 ptg000008l:23615250-23626724 Q7RTR2 1.45e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36862 FUN_013517 391 1668 1260 1640 97 ptg000008l:23615250-23626724 Q7RTR2 9.47e-50 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36863 FUN_013517 391 1668 1260 1640 97 ptg000008l:23615250-23626724 Q7RTR2 1.13e-46 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36864 FUN_013517 391 1668 1260 1640 97 ptg000008l:23615250-23626724 Q7RTR2 1.95e-42 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36865 FUN_013517 391 1668 1260 1640 97 ptg000008l:23615250-23626724 Q7RTR2 1.04e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36866 FUN_013515 81 69 68 229 0 ptg000008l:23582752-23597901 Q99570 4.87e-42 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 36867 FUN_013515 81 69 68 229 0 ptg000008l:23582752-23597901 Q99570 2.77e-21 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 36868 FUN_013515 81 69 68 229 0 ptg000008l:23582752-23597901 Q99570 2.77e-21 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) autophagosome maturation [GO:0097352]; autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; early endosome to late endosome transport [GO:0045022]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol-3-phosphate biosynthetic process [GO:0036092]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to lysosome [GO:0006622]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of autophagy [GO:0010506]; regulation of cytokinesis [GO:0032465]; regulation of macroautophagy [GO:0016241] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006622; GO:0006623; GO:0010506; GO:0015630; GO:0016020; GO:0016236; GO:0016241; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034271; GO:0034272; GO:0035032; GO:0036092; GO:0042149; GO:0043231; GO:0043552; GO:0045022; GO:0045324; GO:0071561; GO:0097352; GO:0106310 36869 FUN_016599 1164 1001 633 1002 831 NA NA NA NA NA NA NA 36870 FUN_016598 0 0 0 9 0 NA NA NA NA NA NA NA 36871 FUN_013510 0 86 0 33 0 NA NA NA NA NA NA NA 36872 FUN_013511 0 7 0 0 0 NA NA NA NA NA NA NA 36873 FUN_043638 7242 8208 4260 5846 2680 ptg000047l:11061241-11066350 B3EWY7 1.17e-44 Acidic skeletal organic matrix protein (Acidic SOMP) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 36874 FUN_043638 7242 8208 4260 5846 2680 ptg000047l:11061241-11066350 B3EWY7 2.01e-36 Acidic skeletal organic matrix protein (Acidic SOMP) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 36875 FUN_043638 7242 8208 4260 5846 2680 ptg000047l:11061241-11066350 B3EWY7 7.61e-34 Acidic skeletal organic matrix protein (Acidic SOMP) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 36876 FUN_043638 7242 8208 4260 5846 2680 ptg000047l:11061241-11066350 B3EWY7 1.37e-22 Acidic skeletal organic matrix protein (Acidic SOMP) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 36877 FUN_043639 68 0 0 26 5 ptg000047l:11068738-11073924 B8VIU6 1.08e-34 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 36878 FUN_043632 3206 2483 974 2180 2742 ptg000047l:11008076-11016640 C9J069 4.75e-30 Apical junction component 1 homolog Homo sapiens (Human) cell-cell junction organization [GO:0045216] GO:0005886; GO:0005912; GO:0005929; GO:0016324; GO:0043296; GO:0045216 36879 FUN_043633 1 2 0 0 15 NA NA NA NA NA NA NA 36880 FUN_043630 1335 888 618 726 895 NA NA NA NA NA NA NA 36881 FUN_043631 1677 826 773 710 380 NA NA NA NA NA NA NA 36882 FUN_043636 2735 1797 1961 1789 1991 NA NA NA NA NA NA NA 36883 FUN_043637 66 220 434 38 109 NA NA NA NA NA NA NA 36884 FUN_043634 2 7 0 0 3 NA NA NA NA NA NA NA 36885 FUN_043635 1138 521 493 1137 993 ptg000047l:11021433-11022465 C9J069 1.95e-28 Apical junction component 1 homolog Homo sapiens (Human) cell-cell junction organization [GO:0045216] GO:0005886; GO:0005912; GO:0005929; GO:0016324; GO:0043296; GO:0045216 36886 FUN_040319 232 17 143 329 197 ptg000031l:6974113-6978992 Q7RTR2 7.07e-45 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36887 FUN_040319 232 17 143 329 197 ptg000031l:6974113-6978992 Q7RTR2 1.52e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36888 FUN_040319 232 17 143 329 197 ptg000031l:6974113-6978992 Q7RTR2 1.78e-36 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36889 FUN_040319 232 17 143 329 197 ptg000031l:6974113-6978992 Q7RTR2 1.04e-30 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 36890 FUN_016048 1663 539 456 813 852 NA NA NA NA NA NA NA 36891 FUN_042327 15926 23200 14855 12292 9272 NA NA NA NA NA NA NA 36892 FUN_016045 627 140 175 412 188 NA NA NA NA NA NA NA 36893 FUN_016044 10 8 0 0 17 NA NA NA NA NA NA NA 36894 FUN_042323 0 0 0 0 9 NA NA NA NA NA NA NA 36895 FUN_042322 539 967 704 744 676 ptg000036l:3754331-3772298 Q95SX7 4.01e-34 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 36896 FUN_042321 519 65 210 70 63 NA NA NA NA NA NA NA 36897 FUN_040212 2 0 0 17 28 NA NA NA NA NA NA NA 36898 FUN_015583 0 0 0 10 9 NA NA NA NA NA NA NA 36899 FUN_015582 329 0 319 150 370 NA NA NA NA NA NA NA 36900 FUN_015588 8 0 7 23 88 NA NA NA NA NA NA NA 36901 FUN_008918 2407 2081 989 1480 982 NA NA NA NA NA NA NA 36902 FUN_008919 2453 2227 1280 1718 1627 NA NA NA NA NA NA NA 36903 FUN_008916 7512 11258 5423 12094 6973 NA NA NA NA NA NA NA 36904 FUN_008917 6941 7980 4581 5629 2851 ptg000004l:521904-524634 A6QQM4 8.35e-54 Zinc finger protein 474 Bos taurus (Bovine) NA GO:0046872 36905 FUN_008917 6941 7980 4581 5629 2851 ptg000004l:521904-524634 A6QQM4 1.26e-50 Zinc finger protein 474 Bos taurus (Bovine) NA GO:0046872 36906 FUN_008914 1082 706 477 720 793 ptg000004l:507159-511593 Q9UJT0 2.27e-110 Tubulin epsilon chain (Epsilon-tubulin) Homo sapiens (Human) centrosome cycle [GO:0007098]; microtubule cytoskeleton organization [GO:0000226]; mitotic cell cycle [GO:0000278] GO:0000226; GO:0000242; GO:0000278; GO:0005200; GO:0005525; GO:0005737; GO:0005874; GO:0007098 36907 FUN_008915 7752 7402 4147 6692 6382 ptg000004l:511759-514280 P58374 1.17e-28 60S ribosomal protein L30 Branchiostoma belcheri (Amphioxus) NA GO:0003723; GO:0003735; GO:0022625 36908 FUN_008912 578 549 356 444 667 NA NA NA NA NA NA NA 36909 FUN_008913 37918 48869 22643 36321 27759 NA NA NA NA NA NA NA 36910 FUN_008910 125 101 148 143 137 NA NA NA NA NA NA NA 36911 FUN_008911 783 379 689 770 566 NA NA NA NA NA NA NA 36912 FUN_040260 2024 1413 881 927 2019 NA NA NA NA NA NA NA 36913 FUN_023629 3306 2601 1834 2381 1869 NA NA NA NA NA NA NA 36914 FUN_023628 0 0 0 13 0 NA NA NA NA NA NA NA 36915 FUN_023623 4712 2108 2805 2332 1193 ptg000017l:10018192-10020854 Q05922 3.04e-26 Dual specificity protein phosphatase 2 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PAC-1) Mus musculus (Mouse) endoderm formation [GO:0001706]; negative regulation of MAPK cascade [GO:0043409]; protein dephosphorylation [GO:0006470] GO:0001706; GO:0004721; GO:0004725; GO:0005634; GO:0005654; GO:0005737; GO:0006470; GO:0008330; GO:0017017; GO:0017018; GO:0031965; GO:0043409; GO:0051019 36916 FUN_023622 885 296 386 310 327 NA NA NA NA NA NA NA 36917 FUN_023621 1891 1625 894 1917 1288 NA NA NA NA NA NA NA 36918 FUN_023620 57 44 32 115 90 NA NA NA NA NA NA NA 36919 FUN_023627 664 742 406 499 388 NA NA NA NA NA NA NA 36920 FUN_023626 7 2 5 0 25 NA NA NA NA NA NA NA 36921 FUN_023625 2910 1606 1925 2278 2903 NA NA NA NA NA NA NA 36922 FUN_023624 142 54 102 77 30 NA NA NA NA NA NA NA 36923 FUN_028635 90 0 31 63 37 NA NA NA NA NA NA NA 36924 FUN_028634 13 15 8 47 18 ptg000022l:1938266-1946221 Q96AY4 1.96e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36925 FUN_028634 13 15 8 47 18 ptg000022l:1938266-1946221 Q96AY4 1.05e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36926 FUN_028634 13 15 8 47 18 ptg000022l:1938266-1946221 Q96AY4 1.64e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36927 FUN_028634 13 15 8 47 18 ptg000022l:1938266-1946221 Q96AY4 4.2e-114 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36928 FUN_028634 13 15 8 47 18 ptg000022l:1938266-1946221 Q96AY4 9.38e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36929 FUN_028637 24 21 169 38 58 NA NA NA NA NA NA NA 36930 FUN_028631 42 0 19 45 11 NA NA NA NA NA NA NA 36931 FUN_028630 0 53 77 11 120 NA NA NA NA NA NA NA 36932 FUN_028633 11 13 13 13 14 NA NA NA NA NA NA NA 36933 FUN_028632 4 0 0 5 6 ptg000022l:1895384-1906559 Q96AY4 1.82e-147 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36934 FUN_028632 4 0 0 5 6 ptg000022l:1895384-1906559 Q96AY4 5.32e-142 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36935 FUN_028632 4 0 0 5 6 ptg000022l:1895384-1906559 Q96AY4 4.33e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36936 FUN_010584 300 273 199 344 273 NA NA NA NA NA NA NA 36937 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 1.59e-84 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36938 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 1.52e-81 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36939 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 6.59e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36940 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 1.35e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36941 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 6.12e-74 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36942 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 6.35e-70 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36943 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 7.37e-65 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36944 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 6.83e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36945 FUN_028639 0 3 0 72 1 ptg000022l:2008018-2009434 Q96AY4 2.6e-61 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36946 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 2.54e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36947 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 2.54e-163 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36948 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 3.24e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36949 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 3.24e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36950 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 4.3e-113 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36951 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 3.43e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36952 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 1.09e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36953 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 1.22e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36954 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 3.34e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36955 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 7.5e-50 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36956 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 1.79e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36957 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 2.17e-49 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36958 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 1.01e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36959 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 5.97e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36960 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 2.2e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36961 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 6.45e-36 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36962 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 1.28e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36963 FUN_028638 0 320 1 210 88 ptg000022l:1982464-1986627 Q96AY4 1.8e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 36964 FUN_040265 386 352 126 605 528 NA NA NA NA NA NA NA 36965 FUN_013378 101 131 20 173 121 ptg000008l:21856518-21858798 O15973 1.4e-23 Rhodopsin, GQ-coupled (GQ-rhodopsin) Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis) phototransduction [GO:0007602]; visual perception [GO:0007601] GO:0004930; GO:0005886; GO:0007601; GO:0007602; GO:0009881 36966 FUN_040266 1013 1310 330 1570 948 NA NA NA NA NA NA NA 36967 FUN_040267 2759 1589 1499 3135 1682 NA NA NA NA NA NA NA 36968 FUN_010588 3177 1509 1148 1167 950 NA NA NA NA NA NA NA 36969 FUN_010589 167 67 44 131 99 NA NA NA NA NA NA NA 36970 FUN_041168 1447 1376 2696 5391 916 NA NA NA NA NA NA NA 36971 FUN_041164 70 34 55 214 72 NA NA NA NA NA NA NA 36972 FUN_041165 663 139 133 199 140 NA NA NA NA NA NA NA 36973 FUN_041166 54 17 80 162 69 NA NA NA NA NA NA NA 36974 FUN_041167 1343 1338 1638 3016 1288 NA NA NA NA NA NA NA 36975 FUN_041162 672 473 295 497 459 NA NA NA NA NA NA NA 36976 FUN_041163 30 0 0 0 0 NA NA NA NA NA NA NA 36977 FUN_011433 44 0 11 4 127 NA NA NA NA NA NA NA 36978 FUN_039698 0 0 210 117 587 NA NA NA NA NA NA NA 36979 FUN_024786 57 43 44 48 12 NA NA NA NA NA NA NA 36980 FUN_011806 1612 1105 898 1472 1436 NA NA NA NA NA NA NA 36981 FUN_011807 20 21 30 9 15 NA NA NA NA NA NA NA 36982 FUN_011804 501 337 198 425 423 ptg000008l:1644249-1647686 Q5BIM8 2.26e-125 DNA excision repair protein ERCC-8 Bos taurus (Bovine) cellular response to DNA damage stimulus [GO:0006974]; double-strand break repair via classical nonhomologous end joining [GO:0097680]; positive regulation of DNA repair [GO:0045739]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of transcription-coupled nucleotide-excision repair [GO:0090262]; response to oxidative stress [GO:0006979]; response to UV [GO:0009411]; response to X-ray [GO:0010165]; single strand break repair [GO:0000012]; transcription-coupled nucleotide-excision repair [GO:0006283] GO:0000012; GO:0000109; GO:0000209; GO:0004842; GO:0006283; GO:0006974; GO:0006979; GO:0009411; GO:0010165; GO:0016363; GO:0031464; GO:0032991; GO:0043161; GO:0044877; GO:0045739; GO:0051865; GO:0090262; GO:0097680 36983 FUN_011805 2572 1078 877 1861 1207 NA NA NA NA NA NA NA 36984 FUN_011802 642 414 550 564 568 ptg000008l:1630064-1636237 Q10MN5 6.4e-39 Kinesin-like protein KIN-14F Oryza sativa subsp. japonica (Rice) microtubule-based movement [GO:0007018]; microtubule-based process [GO:0007017] GO:0003777; GO:0005524; GO:0005874; GO:0007017; GO:0007018; GO:0008017; GO:0015630 36985 FUN_011803 9307 4028 2187 4831 4391 NA NA NA NA NA NA NA 36986 FUN_011800 45 46 31 84 90 ptg000008l:1619987-1621184 Q9GZQ4 1.3e-22 Neuromedin-U receptor 2 (NMU-R2) (G-protein coupled receptor FM-4) (G-protein coupled receptor TGR-1) Homo sapiens (Human) arachidonic acid secretion [GO:0050482]; calcium ion transport [GO:0006816]; calcium-mediated signaling [GO:0019722]; cell-cell signaling [GO:0007267]; central nervous system development [GO:0007417]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; grooming behavior [GO:0007625]; inositol phosphate-mediated signaling [GO:0048016]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; reduction of food intake in response to dietary excess [GO:0002023]; regulation of sensory perception of pain [GO:0051930]; regulation of smooth muscle contraction [GO:0006940]; response to pain [GO:0048265] GO:0001607; GO:0002023; GO:0004930; GO:0005229; GO:0005525; GO:0005886; GO:0006816; GO:0006940; GO:0007186; GO:0007200; GO:0007204; GO:0007218; GO:0007267; GO:0007417; GO:0007625; GO:0007631; GO:0008188; GO:0016020; GO:0019722; GO:0042924; GO:0048016; GO:0048265; GO:0050482; GO:0051930 36987 FUN_011801 817 507 489 693 529 ptg000008l:1622230-1629826 Q80W54 3.94e-29 CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog) Mus musculus (Mouse) adult walking behavior [GO:0007628]; bone mineralization [GO:0030282]; CAAX-box protein processing [GO:0071586]; calcium ion import into sarcoplasmic reticulum [GO:1990036]; CAMKK-AMPK signaling cascade [GO:0061762]; cardiac conduction [GO:0061337]; cardiac muscle cell development [GO:0055013]; cardiac ventricle development [GO:0003231]; cellular lipid metabolic process [GO:0044255]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to gamma radiation [GO:0071480]; chromatin organization [GO:0006325]; chromosome organization [GO:0051276]; determination of adult lifespan [GO:0008340]; DNA repair [GO:0006281]; epidermis development [GO:0008544]; growth plate cartilage development [GO:0003417]; hair follicle development [GO:0001942]; heart morphogenesis [GO:0003007]; histone H2B acetylation [GO:0043969]; histone H2B-K5 acetylation [GO:0043979]; hypomethylation of CpG island [GO:0044029]; inflammatory cell apoptotic process [GO:0006925]; kidney morphogenesis [GO:0060993]; liver development [GO:0001889]; maintenance of rDNA [GO:0043007]; multicellular organism growth [GO:0035264]; negative regulation of gene expression [GO:0010629]; negative regulation of miRNA maturation [GO:1903799]; neuromuscular process [GO:0050905]; nuclear envelope organization [GO:0006998]; nucleus organization [GO:0006997]; positive regulation of gene expression [GO:0010628]; prenylated protein catabolic process [GO:0030327]; protein processing [GO:0016485]; regulation of autophagy [GO:0010506]; regulation of blood circulation [GO:1903522]; regulation of bone mineralization [GO:0030500]; regulation of cell shape [GO:0008360]; regulation of cellular senescence [GO:2000772]; regulation of defense response to virus [GO:0050688]; regulation of DNA damage response, signal transduction by p53 class mediator [GO:0043516]; regulation of DNA methylation [GO:0044030]; regulation of DNA-templated transcription [GO:0006355]; regulation of fibroblast proliferation [GO:0048145]; regulation of glucose metabolic process [GO:0010906]; regulation of heart contraction [GO:0008016]; regulation of histone H4 acetylation [GO:0090239]; regulation of histone H4-K16 acetylation [GO:2000618]; regulation of hormone metabolic process [GO:0032350]; regulation of lipid metabolic process [GO:0019216]; regulation of mitotic cell cycle [GO:0007346]; regulation of mitotic cell cycle DNA replication [GO:1903463]; regulation of multicellular organism growth [GO:0040014]; regulation of RNA polymerase II regulatory region sequence-specific DNA binding [GO:1903025]; regulation of stress-activated protein kinase signaling cascade [GO:0070302]; regulation of termination of RNA polymerase I transcription [GO:2000730]; regulation of TOR signaling [GO:0032006]; regulation of ventricular cardiac muscle cell membrane repolarization [GO:0060307]; response to DNA damage checkpoint signaling [GO:0072423]; thymus development [GO:0048538]; ventricular cardiac muscle tissue development [GO:0003229] GO:0001889; GO:0001942; GO:0003007; GO:0003229; GO:0003231; GO:0003417; GO:0003690; GO:0004175; GO:0004222; GO:0005635; GO:0005637; GO:0005789; GO:0006281; GO:0006325; GO:0006355; GO:0006925; GO:0006974; GO:0006997; GO:0006998; GO:0007346; GO:0007628; GO:0008016; GO:0008340; GO:0008360; GO:0008544; GO:0010506; GO:0010628; GO:0010629; GO:0010906; GO:0016020; GO:0016485; GO:0019216; GO:0030282; GO:0030327; GO:0030500; GO:0032006; GO:0032350; GO:0032991; GO:0035264; GO:0040014; GO:0043007; GO:0043516; GO:0043969; GO:0043979; GO:0044029; GO:0044030; GO:0044255; GO:0046872; GO:0048145; GO:0048538; GO:0050688; GO:0050905; GO:0051276; GO:0055013; GO:0060307; GO:0060993; GO:0061337; GO:0061762; GO:0070302; GO:0071480; GO:0071586; GO:0072423; GO:0090239; GO:1903025; GO:1903463; GO:1903522; GO:1903799; GO:1990036; GO:2000618; GO:2000730; GO:2000772 36988 FUN_011432 0 0 22 0 73 NA NA NA NA NA NA NA 36989 FUN_039697 0 14 0 3 9 NA NA NA NA NA NA NA 36990 FUN_011808 928 906 758 516 398 NA NA NA NA NA NA NA 36991 FUN_011809 2272 508 501 1917 1099 ptg000008l:1707249-1727565 Q5TH69 3.54e-43 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3) Homo sapiens (Human) actin cytoskeleton organization [GO:0030036]; regulation of ARF protein signal transduction [GO:0032012] GO:0005085; GO:0005794; GO:0030036; GO:0030658; GO:0032012 36992 FUN_018157 289 7 357 112 333 NA NA NA NA NA NA NA 36993 FUN_027931 598 185 289 437 354 NA NA NA NA NA NA NA 36994 FUN_018154 0 34 0 0 8 NA NA NA NA NA NA NA 36995 FUN_025708 4 0 126 0 29 NA NA NA NA NA NA NA 36996 FUN_011431 102 40 113 106 87 NA NA NA NA NA NA NA 36997 FUN_025707 8 3 6 20 34 NA NA NA NA NA NA NA 36998 FUN_025704 69 35 69 28 125 NA NA NA NA NA NA NA 36999 FUN_025705 261 133 238 280 360 NA NA NA NA NA NA NA 37000 FUN_025702 3889 2727 1890 2908 3376 NA NA NA NA NA NA NA 37001 FUN_025703 46 26 5 13 41 NA NA NA NA NA NA NA 37002 FUN_025700 3024 2214 1709 3788 3613 NA NA NA NA NA NA NA 37003 FUN_025701 5907 2617 3077 4297 3878 NA NA NA NA NA NA NA 37004 FUN_008008 0 776 168 385 108 NA NA NA NA NA NA NA 37005 FUN_008009 0 17 6 0 7 NA NA NA NA NA NA NA 37006 FUN_008004 95 35 42 0 265 NA NA NA NA NA NA NA 37007 FUN_008005 1781 1862 833 1451 887 ptg000002l:7108947-7109814 P29084 4.54e-66 Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2) Homo sapiens (Human) transcription by RNA polymerase II [GO:0006366]; transcription initiation at RNA polymerase II promoter [GO:0006367] GO:0003677; GO:0003723; GO:0005654; GO:0005669; GO:0005673; GO:0005829; GO:0006366; GO:0006367; GO:0016251; GO:0016607 37008 FUN_008006 1046 1226 838 1338 579 ptg000002l:7112674-7123724 P14912 2.84e-38 4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) Petroselinum crispum (Parsley) (Petroselinum hortense) phenylpropanoid metabolic process [GO:0009698] GO:0005524; GO:0009698; GO:0016207 37009 FUN_008006 1046 1226 838 1338 579 ptg000002l:7112674-7123724 P14912 4.54e-34 4-coumarate--CoA ligase 1 (4CL 1) (EC 6.2.1.12) (4-coumaroyl-CoA synthase 1) Petroselinum crispum (Parsley) (Petroselinum hortense) phenylpropanoid metabolic process [GO:0009698] GO:0005524; GO:0009698; GO:0016207 37010 FUN_008007 0 589 502 373 387 NA NA NA NA NA NA NA 37011 FUN_008000 610 526 333 592 373 NA NA NA NA NA NA NA 37012 FUN_008001 904 456 482 690 1255 NA NA NA NA NA NA NA 37013 FUN_008002 9949 24646 11681 12249 6878 ptg000002l:7095313-7096267 Q99MM4 2.86e-23 TRAF-type zinc finger domain-containing protein 1 (Protein FLN29) Rattus norvegicus (Rat) negative regulation of innate immune response [GO:0045824]; response to cytokine [GO:0034097] GO:0008270; GO:0034097; GO:0045824 37014 FUN_008003 228 168 190 349 461 NA NA NA NA NA NA NA 37015 FUN_014355 16 0 2 0 0 NA NA NA NA NA NA NA 37016 FUN_014353 0 23 0 0 0 NA NA NA NA NA NA NA 37017 FUN_022282 3758 2762 2262 3114 2053 NA NA NA NA NA NA NA 37018 FUN_022283 115 188 42 75 151 NA NA NA NA NA NA NA 37019 FUN_022280 479 577 360 565 405 ptg000016l:7142806-7144129 Q0V9W6 3.28e-110 BTB/POZ domain-containing protein 6 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) NA GO:0005737 37020 FUN_022281 209 251 199 614 168 NA NA NA NA NA NA NA 37021 FUN_022286 143 83 29 70 47 NA NA NA NA NA NA NA 37022 FUN_022287 134 113 65 216 214 NA NA NA NA NA NA NA 37023 FUN_022284 244 2 24 145 72 ptg000016l:7208358-7208733 Q8N0Z2 1.39e-28 Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS) Homo sapiens (Human) positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of Rho protein signal transduction [GO:0035025]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein import into nucleus [GO:0006606]; transcription by RNA polymerase II [GO:0006366] GO:0003779; GO:0005886; GO:0006366; GO:0006606; GO:0015629; GO:0030017; GO:0035025; GO:0045944; GO:0051091 37024 FUN_022285 859 626 235 739 871 NA NA NA NA NA NA NA 37025 FUN_022288 5974 7524 5071 11085 9331 NA NA NA NA NA NA NA 37026 FUN_022289 45 87 65 54 99 NA NA NA NA NA NA NA 37027 FUN_011436 4 3 38 2 107 NA NA NA NA NA NA NA 37028 FUN_014979 0 10 0 18 16 NA NA NA NA NA NA NA 37029 FUN_014978 221 125 196 502 476 NA NA NA NA NA NA NA 37030 FUN_014971 0 0 0 7 0 NA NA NA NA NA NA NA 37031 FUN_014970 161 137 73 133 126 NA NA NA NA NA NA NA 37032 FUN_014973 10 0 0 4 4 NA NA NA NA NA NA NA 37033 FUN_014975 350 360 348 254 202 ptg000009l:4901865-4904114 Q6DGR4 6.34e-50 Protein HGH1 homolog Danio rerio (Zebrafish) (Brachydanio rerio) NA NA 37034 FUN_014974 4595 3487 1573 2632 2378 NA NA NA NA NA NA NA 37035 FUN_014977 1246 491 523 767 747 NA NA NA NA NA NA NA 37036 FUN_014976 12 13 20 10 41 NA NA NA NA NA NA NA 37037 FUN_028723 10 41 0 90 68 ptg000022l:3202567-3203929 Q80XJ3 4.44e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0005737; GO:0005813; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301; GO:0072686; GO:0097431; GO:1990023 37038 FUN_013371 0 8 0 7 9 NA NA NA NA NA NA NA 37039 FUN_038799 2471 3776 1473 1722 916 NA NA NA NA NA NA NA 37040 FUN_038798 715 553 455 533 508 ptg000027l:11528055-11533331 W5PLZ6 1.33e-64 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37041 FUN_038798 715 553 455 533 508 ptg000027l:11528055-11533331 W5PLZ6 3.21e-62 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37042 FUN_038798 715 553 455 533 508 ptg000027l:11528055-11533331 W5PLZ6 1.39e-52 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37043 FUN_038798 715 553 455 533 508 ptg000027l:11528055-11533331 W5PLZ6 3.97e-32 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37044 FUN_038798 715 553 455 533 508 ptg000027l:11528055-11533331 W5PLZ6 5.01e-26 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37045 FUN_038797 1120 364 358 474 360 ptg000027l:11523975-11527814 W5PLZ6 1.35e-62 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37046 FUN_038797 1120 364 358 474 360 ptg000027l:11523975-11527814 W5PLZ6 9.26e-55 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37047 FUN_038797 1120 364 358 474 360 ptg000027l:11523975-11527814 W5PLZ6 3.28e-52 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37048 FUN_038797 1120 364 358 474 360 ptg000027l:11523975-11527814 W5PLZ6 8.03e-29 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37049 FUN_038797 1120 364 358 474 360 ptg000027l:11523975-11527814 W5PLZ6 2.08e-25 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37050 FUN_038796 677 342 257 489 340 ptg000027l:11517310-11521937 W5PLZ6 3.1e-65 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37051 FUN_038796 677 342 257 489 340 ptg000027l:11517310-11521937 W5PLZ6 2.78e-54 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37052 FUN_038796 677 342 257 489 340 ptg000027l:11517310-11521937 W5PLZ6 5.71e-52 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37053 FUN_038796 677 342 257 489 340 ptg000027l:11517310-11521937 W5PLZ6 7.25e-29 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37054 FUN_038796 677 342 257 489 340 ptg000027l:11517310-11521937 W5PLZ6 1.96e-27 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37055 FUN_038795 118 40 220 107 186 ptg000027l:11510263-11514810 W5PLZ6 5.37e-64 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37056 FUN_038795 118 40 220 107 186 ptg000027l:11510263-11514810 W5PLZ6 1.86e-55 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37057 FUN_038795 118 40 220 107 186 ptg000027l:11510263-11514810 W5PLZ6 1.97e-52 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37058 FUN_038795 118 40 220 107 186 ptg000027l:11510263-11514810 W5PLZ6 2.17e-28 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37059 FUN_038795 118 40 220 107 186 ptg000027l:11510263-11514810 W5PLZ6 5.56e-27 Lactase/phlorizin hydrolase (Lactase/glycosylceramidase) [Includes: Lactase (EC 3.2.1.108); Glycosylceramidase (EC 3.2.1.62) (Phlorizin hydrolase)] Ovis aries (Sheep) cellobiose catabolic process [GO:2000892]; glycosylceramide catabolic process [GO:0046477]; lactose catabolic process [GO:0005990]; quercetin catabolic process [GO:1901733] GO:0000016; GO:0004336; GO:0004348; GO:0005990; GO:0008422; GO:0016324; GO:0046477; GO:0140749; GO:1901733; GO:2000892 37060 FUN_038794 180 52 96 156 85 NA NA NA NA NA NA NA 37061 FUN_038793 254 288 191 578 347 NA NA NA NA NA NA NA 37062 FUN_038791 102 36 25 32 44 ptg000027l:11470404-11473216 P84239 5.11e-86 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37063 FUN_038790 1168 1334 595 617 577 ptg000027l:11469697-11470069 Q6PC60 3.31e-60 Histone H2B 3 Danio rerio (Zebrafish) (Brachydanio rerio) nucleosome assembly [GO:0006334] GO:0000785; GO:0000786; GO:0003677; GO:0005634; GO:0006334; GO:0030527; GO:0046982 37064 FUN_015006 795 390 309 611 673 ptg000009l:5214020-5222205 Q5SPL2 1.07e-31 PHD finger protein 12 (PHD factor 1) (Pf1) Mus musculus (Mouse) negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0001222; GO:0003714; GO:0005634; GO:0005654; GO:0006357; GO:0016580; GO:0017053; GO:0035091; GO:0045892; GO:0046872; GO:0070822 37065 FUN_015007 13097 17645 9469 17415 10749 ptg000009l:5225095-5227657 Q90Z08 1.89e-23 Protein unc-119 homolog B (Protein unc-119 homolog 1) Danio rerio (Zebrafish) (Brachydanio rerio) cilium assembly [GO:0060271]; Kupffer's vesicle development [GO:0070121]; lipoprotein transport [GO:0042953]; nervous system development [GO:0007399] GO:0005929; GO:0007399; GO:0008289; GO:0042953; GO:0060271; GO:0070121 37066 FUN_015004 29 0 13 22 20 NA NA NA NA NA NA NA 37067 FUN_015005 777 600 604 754 629 NA NA NA NA NA NA NA 37068 FUN_013084 847 941 598 1124 767 ptg000008l:19221341-19244005 Q9P215 1.44e-27 Pogo transposable element with KRAB domain Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0003677; GO:0005634; GO:0005654; GO:0006355 37069 FUN_015008 2537 1775 900 1725 1794 NA NA NA NA NA NA NA 37070 FUN_015009 15039 14996 8152 9709 4935 NA NA NA NA NA NA NA 37071 FUN_028726 228 320 27 189 296 NA NA NA NA NA NA NA 37072 FUN_013086 0 0 0 9 9 NA NA NA NA NA NA NA 37073 FUN_028724 313 254 43 234 284 NA NA NA NA NA NA NA 37074 FUN_020629 0 0 0 0 8 NA NA NA NA NA NA NA 37075 FUN_022918 1718 1054 895 1163 937 NA NA NA NA NA NA NA 37076 FUN_022919 1688 1277 1187 2686 140 ptg000017l:1458389-1483036 Q8R151 8.87e-90 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 37077 FUN_022919 1688 1277 1187 2686 140 ptg000017l:1458389-1483036 Q8R151 2.45e-71 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 37078 FUN_022919 1688 1277 1187 2686 140 ptg000017l:1458389-1483036 Q8R151 5.89e-45 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 37079 FUN_022919 1688 1277 1187 2686 140 ptg000017l:1458389-1483036 Q8R151 3.63e-38 NFX1-type zinc finger-containing protein 1 Mus musculus (Mouse) activation of innate immune response [GO:0002218]; defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; innate immune response [GO:0045087]; negative regulation of viral genome replication [GO:0045071]; RNA-mediated heterochromatin formation [GO:0031048] GO:0002218; GO:0003723; GO:0004386; GO:0005741; GO:0008270; GO:0010494; GO:0031048; GO:0031380; GO:0042742; GO:0045071; GO:0045087; GO:0051607 37080 FUN_002695 4873 4592 3048 2785 1695 NA NA NA NA NA NA NA 37081 FUN_022912 47 54 43 40 157 NA NA NA NA NA NA NA 37082 FUN_022913 527 305 142 328 269 NA NA NA NA NA NA NA 37083 FUN_022910 119 65 84 72 354 ptg000017l:1368565-1374046 Q6QWR1 1.55e-31 Pyranose 2-oxidase (P2O) (P2Ox) (POD) (POx) (PROD) (Pyranose oxidase) (EC 1.1.3.10) (FAD-oxidoreductase) (Glucose 2-oxidase) (Pyranose:oxygen 2-oxidoreductase) Phanerodontia chrysosporium (White-rot fungus) (Sporotrichum pruinosum) NA GO:0042597; GO:0050233; GO:0050660 37084 FUN_022911 68 57 14 36 0 NA NA NA NA NA NA NA 37085 FUN_022916 1466 1476 680 1327 1056 NA NA NA NA NA NA NA 37086 FUN_022917 217 199 143 266 326 NA NA NA NA NA NA NA 37087 FUN_040064 14 0 78 294 39 NA NA NA NA NA NA NA 37088 FUN_022915 4400 3067 1986 2947 4025 NA NA NA NA NA NA NA 37089 FUN_027399 4 0 6 9 6 NA NA NA NA NA NA NA 37090 FUN_027398 0 0 9 0 24 NA NA NA NA NA NA NA 37091 FUN_027394 0 3 9 0 0 NA NA NA NA NA NA NA 37092 FUN_027392 0 0 8 0 0 NA NA NA NA NA NA NA 37093 FUN_011184 3 0 11 0 124 NA NA NA NA NA NA NA 37094 FUN_019382 300 117 216 204 138 NA NA NA NA NA NA NA 37095 FUN_030098 31 0 0 0 95 NA NA NA NA NA NA NA 37096 FUN_011324 5 0 2 9 36 NA NA NA NA NA NA NA 37097 FUN_030099 0 0 0 0 26 NA NA NA NA NA NA NA 37098 FUN_026116 421 73 31 84 222 NA NA NA NA NA NA NA 37099 FUN_026117 43 0 40 38 56 NA NA NA NA NA NA NA 37100 FUN_026114 300 200 52 461 118 NA NA NA NA NA NA NA 37101 FUN_026115 2114 1263 1300 1836 1982 NA NA NA NA NA NA NA 37102 FUN_026112 9351 5775 7371 5477 4159 NA NA NA NA NA NA NA 37103 FUN_026113 1875 1108 388 726 661 NA NA NA NA NA NA NA 37104 FUN_026111 1477 1397 879 3273 2231 NA NA NA NA NA NA NA 37105 FUN_026118 0 23 16 19 0 NA NA NA NA NA NA NA 37106 FUN_044361 10 0 1 0 9 NA NA NA NA NA NA NA 37107 FUN_044363 1 0 3 5 6 NA NA NA NA NA NA NA 37108 FUN_044362 1 0 2 6 6 NA NA NA NA NA NA NA 37109 FUN_030094 0 4 6 43 8 NA NA NA NA NA NA NA 37110 FUN_044364 7 0 6 10 20 NA NA NA NA NA NA NA 37111 FUN_004059 2125 1463 1068 2468 1222 NA NA NA NA NA NA NA 37112 FUN_004058 149 259 109 198 135 NA NA NA NA NA NA NA 37113 FUN_004053 9 101 87 140 161 NA NA NA NA NA NA NA 37114 FUN_004052 0 0 18 0 29 NA NA NA NA NA NA NA 37115 FUN_004051 63 0 0 0 60 NA NA NA NA NA NA NA 37116 FUN_004050 97 0 44 18 8 ntLink_8:18640868-18641399 A2VDD2 4.46e-26 Dynein light chain Tctex-type 5-B (Tctex1 domain-containing protein 1-B) Xenopus laevis (African clawed frog) NA NA 37117 FUN_004057 2028 1837 1035 1616 1252 ntLink_8:18782780-18784759 Q9V464 2.87e-21 Histone chaperone asf1 (Anti-silencing function protein 1) (Replication-coupling assembly factor subunit ASF1) (RCAF subunit ASF1) (dASF1) Drosophila melanogaster (Fruit fly) chromatin organization [GO:0006325]; DNA replication-dependent chromatin assembly [GO:0006335]; negative regulation of transcription by RNA polymerase II [GO:0000122]; regulation of mRNA splicing, via spliceosome [GO:0048024] GO:0000122; GO:0005634; GO:0005700; GO:0006325; GO:0006335; GO:0017053; GO:0035059; GO:0042393; GO:0048024; GO:0061629 37118 FUN_004056 3396 2048 1978 3538 2737 ntLink_8:18751665-18778245 P14381 3.87e-90 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37119 FUN_004056 3396 2048 1978 3538 2737 ntLink_8:18751665-18778245 P14381 3.87e-90 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37120 FUN_004056 3396 2048 1978 3538 2737 ntLink_8:18751665-18778245 P14381 3.87e-90 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37121 FUN_004055 1140 556 470 724 531 NA NA NA NA NA NA NA 37122 FUN_004054 7294 6115 3592 3160 3096 NA NA NA NA NA NA NA 37123 FUN_018041 386 176 81 116 209 ptg000012l:3712270-3716496 A7SFB5 3.64e-29 Cyclic GMP-AMP synthase (NvcGAS) (cGAMP synthase) (cGAS) (nv-cGAS) (EC 2.7.7.86) (3'3'-cGAMP synthase) Nematostella vectensis (Starlet sea anemone) NA GO:0005524; GO:0005525; GO:0005829; GO:0046872; GO:0061501 37124 FUN_018040 208 301 135 280 191 ptg000012l:3708578-3710092 Q3MHY7 9.78e-22 39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10) Bos taurus (Bovine) translation [GO:0006412] GO:0003735; GO:0005654; GO:0005743; GO:0005762; GO:0006412; GO:0015934; GO:1990904 37125 FUN_018043 59 28 21 21 21 ptg000012l:3735459-3736635 Q8WPA2 3.69e-27 Allatostatin-A receptor (BAR) Bombyx mori (Silk moth) NA GO:0004930; GO:0005886; GO:0042562; GO:0042923 37126 FUN_018042 278 83 181 236 199 NA NA NA NA NA NA NA 37127 FUN_018045 247 94 145 142 186 NA NA NA NA NA NA NA 37128 FUN_018044 1523 1504 772 1516 1057 ptg000012l:3742285-3748193 Q3ZCH9 1.2e-31 Haloacid dehalogenase-like hydrolase domain-containing protein 2 Bos taurus (Bovine) dephosphorylation [GO:0016311] GO:0016311; GO:0016791; GO:0019899; GO:0046872 37129 FUN_018044 1523 1504 772 1516 1057 ptg000012l:3742285-3748193 Q3ZCH9 3.12e-27 Haloacid dehalogenase-like hydrolase domain-containing protein 2 Bos taurus (Bovine) dephosphorylation [GO:0016311] GO:0016311; GO:0016791; GO:0019899; GO:0046872 37130 FUN_018047 79 113 134 110 229 NA NA NA NA NA NA NA 37131 FUN_018046 402 414 242 324 516 NA NA NA NA NA NA NA 37132 FUN_018049 41 32 218 70 134 NA NA NA NA NA NA NA 37133 FUN_018048 577 545 140 438 178 NA NA NA NA NA NA NA 37134 FUN_014851 3039 2446 1659 1715 2029 ptg000009l:3687584-3690105 Q9XWN7 1.85e-26 Nucleoside hydrolase (EC 3.2.2.-) (EC 3.2.2.1) (EC 3.2.2.2) (EC 3.2.2.3) (EC 3.2.2.7) (EC 3.2.2.8) Caenorhabditis elegans nucleobase-containing compound metabolic process [GO:0006139]; organonitrogen compound metabolic process [GO:1901564] GO:0006139; GO:0016799; GO:0046872; GO:1901564 37135 FUN_033851 0 0 0 3 17 ptg000024l:1867633-1872772 D3YXG0 1.26e-24 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37136 FUN_033851 0 0 0 3 17 ptg000024l:1867633-1872772 D3YXG0 7.18e-21 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37137 FUN_033850 0 0 42 3 44 NA NA NA NA NA NA NA 37138 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 4.08e-43 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37139 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 2.03e-39 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37140 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 1.56e-32 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37141 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 7.27e-32 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37142 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 2.39e-30 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37143 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 1.32e-27 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37144 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 8.67e-25 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37145 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 3.42e-21 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37146 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 3.69e-21 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37147 FUN_033855 3338 1632 2078 4369 2513 ptg000024l:1916948-1937010 O75581 9.38e-21 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37148 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 4.29e-41 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37149 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 2.34e-37 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37150 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 2.97e-30 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37151 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 6.23e-30 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37152 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 8.97e-29 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37153 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 3.99e-26 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37154 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 1.38e-24 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37155 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 2.82e-22 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37156 FUN_033854 1219 595 695 1409 1265 ptg000024l:1880138-1898014 O75581 3.54e-21 Low-density lipoprotein receptor-related protein 6 (LRP-6) Homo sapiens (Human) canonical Wnt signaling pathway [GO:0060070]; canonical Wnt signaling pathway involved in neural crest cell differentiation [GO:0044335]; canonical Wnt signaling pathway involved in regulation of cell proliferation [GO:0044340]; cell-cell adhesion [GO:0098609]; cellular response to cholesterol [GO:0071397]; chemical synaptic transmission [GO:0007268]; dopaminergic neuron differentiation [GO:0071542]; midbrain dopaminergic neuron differentiation [GO:1904948]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of smooth muscle cell apoptotic process [GO:0034392]; neural crest cell differentiation [GO:0014033]; neural crest formation [GO:0014029]; positive regulation of cell cycle [GO:0045787]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of DNA-templated transcription [GO:0045893]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein localization to plasma membrane [GO:0072659]; receptor-mediated endocytosis involved in cholesterol transport [GO:0090118]; response to peptide hormone [GO:0043434]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation [GO:1904953]; Wnt signaling pathway involved in somitogenesis [GO:0090244] GO:0001933; GO:0005041; GO:0005102; GO:0005109; GO:0005576; GO:0005783; GO:0005886; GO:0006469; GO:0007204; GO:0007268; GO:0009986; GO:0014029; GO:0014033; GO:0016055; GO:0017147; GO:0019210; GO:0019534; GO:0031410; GO:0031901; GO:0034392; GO:0042802; GO:0042803; GO:0042813; GO:0043025; GO:0043434; GO:0044335; GO:0044340; GO:0045121; GO:0045202; GO:0045787; GO:0045893; GO:0045944; GO:0051091; GO:0060070; GO:0071397; GO:0071542; GO:0071901; GO:0071936; GO:0072659; GO:0090118; GO:0090244; GO:0098609; GO:1904928; GO:1904948; GO:1904953; GO:1990851; GO:1990909 37157 FUN_033857 4009 2101 1103 2157 1590 ptg000024l:1964997-1977018 Q3ZC84 1.25e-21 Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Threonyl dipeptidase) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0046872; GO:0070573; GO:0103046 37158 FUN_033856 995 486 926 526 362 ptg000024l:1945168-1961062 Q3ZC84 1.69e-21 Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Threonyl dipeptidase) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004180; GO:0005654; GO:0005829; GO:0006508; GO:0008233; GO:0016805; GO:0046872; GO:0070573; GO:0103046 37159 FUN_033859 2785 3419 2107 2877 2016 NA NA NA NA NA NA NA 37160 FUN_033858 2056 1196 1229 2377 2338 NA NA NA NA NA NA NA 37161 FUN_031981 1475 520 886 1144 950 ptg000023l:27445793-27458085 A7RZW4 1.99e-26 Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) Nematostella vectensis (Starlet sea anemone) proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0006508; GO:0008235; GO:0008239; GO:0046872 37162 FUN_031981 1475 520 886 1144 950 ptg000023l:27445793-27458085 A7RZW4 6.16e-24 Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) Nematostella vectensis (Starlet sea anemone) proteolysis [GO:0006508] GO:0004177; GO:0005737; GO:0006508; GO:0008235; GO:0008239; GO:0046872 37163 FUN_031980 613 331 239 413 580 NA NA NA NA NA NA NA 37164 FUN_031983 1616 1502 1330 2522 1360 ptg000023l:27461253-27462516 Q8NBN7 5.6e-101 Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) Homo sapiens (Human) eye photoreceptor cell development [GO:0042462]; response to high light intensity [GO:0009644]; retina layer formation [GO:0010842]; retinal metabolic process [GO:0042574] GO:0005743; GO:0009644; GO:0010842; GO:0042462; GO:0042574; GO:0052650 37165 FUN_031982 362 120 386 131 93 ptg000023l:27458185-27459485 Q29081 2.92e-67 Phosphomevalonate kinase (PMKase) (EC 2.7.4.2) Sus scrofa (Pig) cholesterol biosynthetic process [GO:0006695]; isopentenyl diphosphate biosynthetic process, mevalonate pathway [GO:0019287]; phosphorylation [GO:0016310]; response to cholesterol [GO:0070723] GO:0004631; GO:0005524; GO:0005829; GO:0006695; GO:0016310; GO:0019287; GO:0070723 37166 FUN_031985 7 6 0 21 42 NA NA NA NA NA NA NA 37167 FUN_031984 0 0 0 0 35 NA NA NA NA NA NA NA 37168 FUN_031987 80 38 0 33 26 NA NA NA NA NA NA NA 37169 FUN_031986 13 21 0 42 41 NA NA NA NA NA NA NA 37170 FUN_031989 0 0 0 21 33 NA NA NA NA NA NA NA 37171 FUN_031988 39 0 0 82 97 NA NA NA NA NA NA NA 37172 FUN_007163 611 473 324 571 319 NA NA NA NA NA NA NA 37173 FUN_009354 25 18 2 2 3 NA NA NA NA NA NA NA 37174 FUN_013875 0 15 0 39 3 NA NA NA NA NA NA NA 37175 FUN_019396 40 10 97 81 28 NA NA NA NA NA NA NA 37176 FUN_019397 111 0 47 109 170 NA NA NA NA NA NA NA 37177 FUN_019394 273 57 105 270 78 NA NA NA NA NA NA NA 37178 FUN_019395 547 128 119 301 56 NA NA NA NA NA NA NA 37179 FUN_019392 39 0 14 35 16 NA NA NA NA NA NA NA 37180 FUN_019393 24 3 0 0 10 NA NA NA NA NA NA NA 37181 FUN_019390 5 138 54 6 12 NA NA NA NA NA NA NA 37182 FUN_019391 16 0 0 9 17 NA NA NA NA NA NA NA 37183 FUN_019398 1 0 11 0 31 NA NA NA NA NA NA NA 37184 FUN_019399 175 192 6 157 98 ptg000015l:1840572-1844826 A1L314 8.88e-86 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) (Protein MPS1) Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 37185 FUN_019399 175 192 6 157 98 ptg000015l:1840572-1844826 A1L314 1.46e-33 Macrophage-expressed gene 1 protein (Macrophage gene 1 protein) (Mpg-1) (Perforin-2) (P-2) (Protein MPS1) Mus musculus (Mouse) antibacterial innate immune response [GO:0140367]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; disruption by host of symbiont membrane [GO:0052337] GO:0030659; GO:0031410; GO:0042742; GO:0045335; GO:0050829; GO:0050830; GO:0052337; GO:0140367 37186 FUN_008765 399 844 30 187 36 NA NA NA NA NA NA NA 37187 FUN_005863 1106 2191 740 1269 541 NA NA NA NA NA NA NA 37188 FUN_005864 1115 2680 792 1388 934 NA NA NA NA NA NA NA 37189 FUN_005867 0 0 0 0 19 NA NA NA NA NA NA NA 37190 FUN_005866 0 0 0 0 11 NA NA NA NA NA NA NA 37191 FUN_019020 190 173 246 225 89 NA NA NA NA NA NA NA 37192 FUN_019021 4696 1400 2254 5853 4991 ptg000012l:16360761-16370836 Q8R1Q3 5.93e-36 Angiopoietin-related protein 7 (Angiopoietin-like protein 7) Mus musculus (Mouse) negative regulation of vasculature development involved in avascular cornea development in camera-type eye [GO:1901346]; regulation of extracellular matrix organization [GO:1903053] GO:0005102; GO:0005576; GO:0005615; GO:0042802; GO:0062023; GO:1901346; GO:1903053 37193 FUN_019023 37 0 0 26 58 NA NA NA NA NA NA NA 37194 FUN_019024 9 0 0 0 98 NA NA NA NA NA NA NA 37195 FUN_019025 747 179 96 1137 846 NA NA NA NA NA NA NA 37196 FUN_019026 2271 1053 1174 1941 623 ptg000012l:16421139-16437066 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37197 FUN_019026 2271 1053 1174 1941 623 ptg000012l:16421139-16437066 Q9NZJ4 1.14e-56 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37198 FUN_019026 2271 1053 1174 1941 623 ptg000012l:16421139-16437066 Q9NZJ4 8.97e-50 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37199 FUN_019026 2271 1053 1174 1941 623 ptg000012l:16421139-16437066 Q9NZJ4 1.88e-22 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37200 FUN_006987 2084 1518 1211 2251 1779 ptg000001l:19075408-19081929 O60841 2.27e-33 Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2) Homo sapiens (Human) regulation of translational initiation [GO:0006446]; translational initiation [GO:0006413] GO:0003723; GO:0003743; GO:0003924; GO:0005525; GO:0005737; GO:0005739; GO:0005829; GO:0006413; GO:0006446; GO:0045202; GO:0046872 37201 FUN_006986 1660 925 818 2203 2326 NA NA NA NA NA NA NA 37202 FUN_006985 1576 1098 596 1247 919 ptg000001l:19044784-19057556 O08759 1.21e-88 Ubiquitin-protein ligase E3A (EC 2.3.2.26) (HECT-type ubiquitin transferase E3A) (Oncogenic protein-associated protein E6-AP) Mus musculus (Mouse) androgen receptor signaling pathway [GO:0030521]; cellular response to brain-derived neurotrophic factor stimulus [GO:1990416]; locomotory exploration behavior [GO:0035641]; modulation of chemical synaptic transmission [GO:0050804]; motor learning [GO:0061743]; negative regulation of dendritic spine morphogenesis [GO:0061002]; ovarian follicle development [GO:0001541]; positive regulation of Golgi lumen acidification [GO:1905528]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of transcription by RNA polymerase II [GO:0045944]; progesterone receptor signaling pathway [GO:0050847]; prostate gland growth [GO:0060736]; protein autoubiquitination [GO:0051865]; protein K48-linked ubiquitination [GO:0070936]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of circadian rhythm [GO:0042752]; regulation of ubiquitin-dependent protein catabolic process [GO:2000058]; response to cocaine [GO:0042220]; response to hydrogen peroxide [GO:0042542]; response to progesterone [GO:0032570]; rhythmic process [GO:0048511]; sperm entry [GO:0035037]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000209; GO:0000502; GO:0001541; GO:0003713; GO:0004842; GO:0005634; GO:0005829; GO:0006511; GO:0014068; GO:0016567; GO:0030521; GO:0031398; GO:0032570; GO:0035037; GO:0035641; GO:0042220; GO:0042542; GO:0042752; GO:0045944; GO:0046872; GO:0048511; GO:0050804; GO:0050847; GO:0051865; GO:0060736; GO:0061002; GO:0061630; GO:0061743; GO:0070936; GO:0098978; GO:1905528; GO:1990416; GO:2000058 37203 FUN_006984 753 954 1262 834 518 ptg000001l:19036550-19038957 O42412 5.28e-22 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 37204 FUN_006983 657 190 447 630 365 ptg000001l:19030434-19032184 O42412 4.63e-25 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 37205 FUN_006982 1385 954 906 1008 744 ptg000001l:19023373-19024397 O42412 1.32e-29 Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) Gallus gallus (Chicken) hormone biosynthetic process [GO:0042446]; thyroid hormone metabolic process [GO:0042403] GO:0004800; GO:0005886; GO:0010008; GO:0033798; GO:0042403; GO:0042446 37206 FUN_006981 646 501 282 609 318 NA NA NA NA NA NA NA 37207 FUN_006980 5360 5528 2873 4733 4803 ptg000001l:18994144-19001473 P54359 7.04e-22 Septin-2 Drosophila melanogaster (Fruit fly) cellularization [GO:0007349]; cytoskeleton-dependent cytokinesis [GO:0061640]; growth of a germarium-derived egg chamber [GO:0007295]; imaginal disc development [GO:0007444]; regulation of cell cycle [GO:0051726] GO:0003924; GO:0005525; GO:0005819; GO:0005940; GO:0007295; GO:0007349; GO:0007444; GO:0015630; GO:0031105; GO:0032153; GO:0042803; GO:0051726; GO:0060090; GO:0061640 37208 FUN_006989 16 0 0 0 0 NA NA NA NA NA NA NA 37209 FUN_006988 2218 1306 762 1715 1536 NA NA NA NA NA NA NA 37210 FUN_034858 1736 1041 456 1973 1512 NA NA NA NA NA NA NA 37211 FUN_034859 1008 725 902 1002 921 NA NA NA NA NA NA NA 37212 FUN_034850 48 69 0 79 48 NA NA NA NA NA NA NA 37213 FUN_034851 0 0 0 27 20 ptg000025l:802975-804456 Q6DIV6 1.66e-75 Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) beta-alanine transport [GO:0001762]; gamma-aminobutyric acid import [GO:0051939]; gamma-aminobutyric acid transport [GO:0015812]; glycine transport [GO:0015816]; neurotransmitter transport [GO:0006836] GO:0001762; GO:0006836; GO:0008021; GO:0015185; GO:0015187; GO:0015812; GO:0015816; GO:0030659; GO:0042995; GO:0051939; GO:0098793; GO:0140799; GO:0140800 37214 FUN_034852 1170 429 725 751 873 ptg000025l:807521-815205 Q92050 5e-28 Protein Wnt-5b Danio rerio (Zebrafish) (Brachydanio rerio) ameboidal-type cell migration [GO:0001667]; angiogenesis [GO:0001525]; canonical Wnt signaling pathway [GO:0060070]; cartilage morphogenesis [GO:0060536]; cell fate commitment [GO:0045165]; cell migration involved in gastrulation [GO:0042074]; chondrocyte differentiation [GO:0002062]; convergent extension [GO:0060026]; convergent extension involved in axis elongation [GO:0060028]; convergent extension involved in gastrulation [GO:0060027]; dorsal convergence [GO:0060030]; embryonic body morphogenesis [GO:0010172]; embryonic cranial skeleton morphogenesis [GO:0048701]; embryonic viscerocranium morphogenesis [GO:0048703]; endochondral ossification [GO:0001958]; endocrine pancreas development [GO:0031018]; fin regeneration [GO:0031101]; lymphangiogenesis [GO:0001946]; midbrain-hindbrain boundary morphogenesis [GO:0021555]; muscle cell differentiation [GO:0042692]; neuromast development [GO:0048884]; neuron differentiation [GO:0030182]; ossification [GO:0001503]; otolith development [GO:0048840]; positive regulation of convergent extension involved in gastrulation [GO:1904105]; positive regulation of non-canonical Wnt signaling pathway [GO:2000052]; post-anal tail morphogenesis [GO:0036342]; regulation of Wnt signaling pathway, calcium modulating pathway [GO:0008591]; release of sequestered calcium ion into cytosol [GO:0051209]; skeletal system development [GO:0001501]; somite development [GO:0061053]; thrombocyte differentiation [GO:0002574]; unidimensional cell growth [GO:0009826]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] GO:0001501; GO:0001503; GO:0001525; GO:0001667; GO:0001946; GO:0001958; GO:0002062; GO:0002574; GO:0005102; GO:0005109; GO:0005125; GO:0005615; GO:0007223; GO:0008591; GO:0009826; GO:0010172; GO:0021555; GO:0030182; GO:0031018; GO:0031101; GO:0036342; GO:0042074; GO:0042692; GO:0045165; GO:0048701; GO:0048703; GO:0048840; GO:0048884; GO:0051209; GO:0060026; GO:0060027; GO:0060028; GO:0060030; GO:0060070; GO:0060536; GO:0061053; GO:1904105; GO:2000052 37215 FUN_034853 220 222 140 156 134 NA NA NA NA NA NA NA 37216 FUN_034854 15216 11799 6387 16049 14242 NA NA NA NA NA NA NA 37217 FUN_034855 265 233 326 374 581 ptg000025l:823918-825625 P33727 3.39e-164 Arylsulfatase B (ASB) (EC 3.1.6.12) (N-acetylgalactosamine-4-sulfatase) (G4S) Felis catus (Cat) (Felis silvestris catus) colon epithelial cell migration [GO:0061580]; positive regulation of neuron projection development [GO:0010976]; regulation of epithelial cell migration [GO:0010632] GO:0003943; GO:0005764; GO:0009986; GO:0010632; GO:0010976; GO:0046872; GO:0061580 37218 FUN_034856 2970 2868 2241 2215 1900 NA NA NA NA NA NA NA 37219 FUN_034857 381 286 380 738 540 NA NA NA NA NA NA NA 37220 FUN_035189 20 0 0 54 20 NA NA NA NA NA NA NA 37221 FUN_035188 0 0 0 195 80 NA NA NA NA NA NA NA 37222 FUN_030359 10 0 4 0 32 ptg000023l:10693614-10694377 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37223 FUN_035185 2033 1485 1113 1768 958 NA NA NA NA NA NA NA 37224 FUN_030355 4 0 8 0 25 ptg000023l:10685510-10686273 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37225 FUN_035181 709 643 379 700 586 NA NA NA NA NA NA NA 37226 FUN_035183 190 196 73 162 63 NA NA NA NA NA NA NA 37227 FUN_006363 0 0 30 0 0 NA NA NA NA NA NA NA 37228 FUN_006362 80 0 0 0 14 ptg000001l:11456486-11467444 S8FIE4 4.83e-41 Laccase-1 (EC 1.10.3.2) (FpLCC1) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 37229 FUN_006361 16 0 0 4 0 ptg000001l:11430918-11435043 S8FGV1 3.39e-40 Laccase-2 (EC 1.10.3.2) (FpLCC2) Fomitopsis pinicola (strain FP-58527) (Brown rot fungus) NA GO:0005507; GO:0005576; GO:0016682 37230 FUN_006367 3291 2501 1844 1838 1222 NA NA NA NA NA NA NA 37231 FUN_042128 1349 411 791 812 1497 ptg000036l:944167-950295 O15439 1.05e-69 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 37232 FUN_042128 1349 411 791 812 1497 ptg000036l:944167-950295 O15439 7.61e-53 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 37233 FUN_042128 1349 411 791 812 1497 ptg000036l:944167-950295 O15439 1.82e-25 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 37234 FUN_042128 1349 411 791 812 1497 ptg000036l:944167-950295 O15439 4.5e-25 ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) Homo sapiens (Human) bile acid and bile salt transport [GO:0015721]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; platelet degranulation [GO:0002576]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104]; urate transport [GO:0015747]; xenobiotic metabolic process [GO:0006805]; xenobiotic transmembrane transport [GO:0006855] GO:0001409; GO:0002576; GO:0005524; GO:0005730; GO:0005794; GO:0005886; GO:0006805; GO:0006855; GO:0008559; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016404; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0042626; GO:0042910; GO:0043225; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115; GO:0140359; GO:0150104 37235 FUN_006365 110 0 0 0 30 ptg000001l:11502354-11512041 Q8LPL3 1.62e-38 L-ascorbate oxidase (AAO) (AO) (ASO) (Ascorbase) (EC 1.10.3.3) Arabidopsis thaliana (Mouse-ear cress) defense response [GO:0006952]; L-ascorbic acid catabolic process [GO:0019854]; negative regulation of defense response to virus [GO:0050687]; negative regulation of response to salt stress [GO:1901001]; response to hydrogen peroxide [GO:0042542]; response to oxidative stress [GO:0006979]; response to salt stress [GO:0009651]; response to virus [GO:0009615] GO:0005507; GO:0005576; GO:0006952; GO:0006979; GO:0008447; GO:0009536; GO:0009615; GO:0009651; GO:0016491; GO:0019854; GO:0042542; GO:0050687; GO:1901001 37236 FUN_042125 232 73 377 18 744 NA NA NA NA NA NA NA 37237 FUN_042124 12 0 84 0 340 NA NA NA NA NA NA NA 37238 FUN_042127 496 97 295 200 463 NA NA NA NA NA NA NA 37239 FUN_042126 410 24 250 156 253 NA NA NA NA NA NA NA 37240 FUN_042121 0 0 36 0 141 NA NA NA NA NA NA NA 37241 FUN_042120 0 3 12 0 0 NA NA NA NA NA NA NA 37242 FUN_042123 36 0 78 0 365 NA NA NA NA NA NA NA 37243 FUN_036988 129 104 47 64 139 NA NA NA NA NA NA NA 37244 FUN_036989 0 0 0 0 16 NA NA NA NA NA NA NA 37245 FUN_036980 942 747 490 965 938 NA NA NA NA NA NA NA 37246 FUN_036981 6 10 8 32 9 NA NA NA NA NA NA NA 37247 FUN_036982 95 165 48 157 190 NA NA NA NA NA NA NA 37248 FUN_036983 3525 2061 1806 4002 4630 ptg000026l:4205612-4222918 Q19768 1.43e-27 Receptor-type guanylate cyclase gcy-13 (EC 4.6.1.2) Caenorhabditis elegans cGMP biosynthetic process [GO:0006182]; chemosensory behavior [GO:0007635]; chemotaxis [GO:0006935]; intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; receptor guanylyl cyclase signaling pathway [GO:0007168]; response to metal ion [GO:0010038]; signal transduction [GO:0007165] GO:0001653; GO:0004383; GO:0004672; GO:0005524; GO:0005525; GO:0005886; GO:0006182; GO:0006468; GO:0006935; GO:0007165; GO:0007168; GO:0007635; GO:0010038; GO:0035556 37249 FUN_036984 366 145 125 138 156 ptg000026l:4227482-4230223 O08755 5.94e-25 Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1) (One cut homeobox 1) Mus musculus (Mouse) anatomical structure morphogenesis [GO:0009653]; B cell differentiation [GO:0030183]; cell fate commitment [GO:0045165]; cell migration [GO:0016477]; cilium assembly [GO:0060271]; endocrine pancreas development [GO:0031018]; endoderm development [GO:0007492]; enteroendocrine cell differentiation [GO:0035883]; epithelial cell development [GO:0002064]; glucose metabolic process [GO:0006006]; liver development [GO:0001889]; negative regulation of transforming growth factor beta receptor signaling pathway [GO:0030512]; Notch signaling pathway [GO:0007219]; pancreas development [GO:0031016]; pancreatic A cell differentiation [GO:0003310]; pancreatic D cell differentiation [GO:0003311]; positive regulation of cell migration [GO:0030335]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of cell-matrix adhesion [GO:0001952]; regulation of transcription by RNA polymerase II [GO:0006357]; spleen development [GO:0048536]; transforming growth factor beta receptor signaling pathway [GO:0007179]; type B pancreatic cell differentiation [GO:0003309] GO:0000978; GO:0000981; GO:0001228; GO:0001889; GO:0001952; GO:0002064; GO:0003309; GO:0003310; GO:0003311; GO:0003677; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0006006; GO:0006357; GO:0007179; GO:0007219; GO:0007492; GO:0009653; GO:0016477; GO:0030183; GO:0030335; GO:0030512; GO:0031016; GO:0031018; GO:0035883; GO:0045165; GO:0045944; GO:0048536; GO:0060271; GO:1990837 37250 FUN_036985 721 56 303 547 376 ptg000026l:4231121-4241632 Q96AY4 1.56e-134 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37251 FUN_036985 721 56 303 547 376 ptg000026l:4231121-4241632 Q96AY4 2.94e-127 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37252 FUN_036985 721 56 303 547 376 ptg000026l:4231121-4241632 Q96AY4 2.12e-69 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37253 FUN_036985 721 56 303 547 376 ptg000026l:4231121-4241632 Q96AY4 2.53e-37 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37254 FUN_036985 721 56 303 547 376 ptg000026l:4231121-4241632 Q96AY4 6.84e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37255 FUN_036986 33 0 0 54 22 NA NA NA NA NA NA NA 37256 FUN_036987 20 0 0 8 2 NA NA NA NA NA NA NA 37257 FUN_036000 30 30 0 44 16 NA NA NA NA NA NA NA 37258 FUN_035728 3820 1211 1315 3744 1618 ptg000025l:11049499-11052511 Q26636 6.33e-38 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 37259 FUN_035728 3820 1211 1315 3744 1618 ptg000025l:11049499-11052511 Q26636 4.33e-21 Cathepsin L (EC 3.4.22.15) [Cleaved into: Cathepsin L heavy chain; Cathepsin L light chain] Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina) cell differentiation [GO:0030154]; proteolysis [GO:0006508] GO:0004197; GO:0005764; GO:0006508; GO:0030154 37260 FUN_031050 20 0 3 0 14 NA NA NA NA NA NA NA 37261 FUN_035720 2225 2068 795 886 809 ptg000025l:10966730-10972647 E2RDZ6 1.75e-51 NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 2.3.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5) Canis lupus familiaris (Dog) (Canis familiaris) peptidyl-lysine demalonylation [GO:0036047]; peptidyl-lysine desuccinylation [GO:0036049]; protein deacetylation [GO:0006476]; protein deglutarylation [GO:0061698]; protein demalonylation [GO:0036046]; protein desuccinylation [GO:0036048]; regulation of ketone biosynthetic process [GO:0010566] GO:0005634; GO:0005739; GO:0005829; GO:0006476; GO:0008270; GO:0010566; GO:0016740; GO:0034979; GO:0036046; GO:0036047; GO:0036048; GO:0036049; GO:0036054; GO:0036055; GO:0061697; GO:0061698; GO:0070403 37262 FUN_035723 949 594 415 979 1132 NA NA NA NA NA NA NA 37263 FUN_035722 410 287 270 507 377 NA NA NA NA NA NA NA 37264 FUN_035725 727 1671 480 819 518 NA NA NA NA NA NA NA 37265 FUN_035724 176 256 91 127 150 NA NA NA NA NA NA NA 37266 FUN_036004 345 555 300 491 203 ptg000025l:14379057-14382986 Q3U145 4.34e-36 Transmembrane protein 64 Mus musculus (Mouse) negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of osteoblast differentiation [GO:0045668]; osteoclast differentiation [GO:0030316]; positive regulation of bone resorption [GO:0045780]; positive regulation of fat cell differentiation [GO:0045600]; positive regulation of osteoclast differentiation [GO:0045672]; regulation of ATP-dependent activity [GO:0043462]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0005783; GO:0016020; GO:0030316; GO:0043462; GO:0045600; GO:0045668; GO:0045672; GO:0045780; GO:0051480; GO:0090090 37267 FUN_004808 13 14 0 17 4 ntLink_8:27261216-27264540 Q54T82 1.25e-23 Putative leucine-rich repeat-containing protein DDB_G0281931 Dictyostelium discoideum (Social amoeba) NA GO:0016020 37268 FUN_004809 166 30 110 68 0 ntLink_8:27266718-27271695 Q9FL28 6.85e-25 LRR receptor-like serine/threonine-protein kinase FLS2 (EC 2.7.11.1) (Protein FLAGELLIN-SENSING 2) (Protein FLAGELLIN-SENSITIVE 2) Arabidopsis thaliana (Mouse-ear cress) defense response by callose deposition in cell wall [GO:0052544]; defense response to bacterium [GO:0042742]; detection of bacterium [GO:0016045]; protein phosphorylation [GO:0006468]; receptor-mediated endocytosis [GO:0006898]; regulation of anion channel activity [GO:0010359] GO:0004675; GO:0005524; GO:0005768; GO:0005886; GO:0006468; GO:0006898; GO:0010008; GO:0010359; GO:0012505; GO:0016020; GO:0016045; GO:0042742; GO:0042802; GO:0052544; GO:0106310 37269 FUN_042694 10 0 7 0 14 ptg000040l:37345-38289 Q6LAF1 7.64e-40 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37270 FUN_042690 10 11 140 60 554 NA NA NA NA NA NA NA 37271 FUN_003857 175 81 516 421 563 ntLink_8:16224349-16235728 A0A0C2SRU0 1.06e-76 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 37272 FUN_003857 175 81 516 421 563 ntLink_8:16224349-16235728 A0A0C2SRU0 2.1e-74 Decarboxylase iboD (EC 4.1.1.-) (Ibotenic acid biosynthesis cluster protein D) Amanita muscaria (strain Koide BX008) phospholipid biosynthetic process [GO:0008654] GO:0004609; GO:0008654 37273 FUN_004802 108 0 0 179 51 NA NA NA NA NA NA NA 37274 FUN_004803 2564 1377 1435 2414 1979 NA NA NA NA NA NA NA 37275 FUN_003852 158 81 57 77 166 ntLink_8:16120514-16126968 Q9BRB3 1.58e-27 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) Homo sapiens (Human) carbohydrate metabolic process [GO:0005975]; GPI anchor biosynthetic process [GO:0006506] GO:0000506; GO:0005783; GO:0005789; GO:0005975; GO:0006506 37276 FUN_003853 619 115 234 390 517 NA NA NA NA NA NA NA 37277 FUN_003851 10382 7087 6243 9751 3494 NA NA NA NA NA NA NA 37278 FUN_031408 0 26 0 5 3 NA NA NA NA NA NA NA 37279 FUN_031409 91 30 30 11 29 NA NA NA NA NA NA NA 37280 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 4.22e-67 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37281 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 4.15e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37282 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 9.92e-65 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37283 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 5.33e-64 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37284 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 2.64e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37285 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 6.03e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37286 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 6.14e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37287 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 9.24e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37288 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 2.07e-62 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37289 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 1.85e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37290 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 4.76e-59 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37291 FUN_031404 116 70 821 32 1054 ptg000023l:20721532-20729649 Q7RTR2 5.64e-55 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37292 FUN_031405 42 77 28 65 42 ptg000023l:20752022-20752334 Q8D3M4 3.48e-27 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Vibrio vulnificus (strain CMCP6) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 37293 FUN_031406 59 70 28 27 40 ptg000023l:20753231-20754891 B9IUR6 2.08e-43 2-aminoethylphosphonate--pyruvate transaminase (EC 2.6.1.37) (2-aminoethylphosphonate aminotransferase) (AEP transaminase) (AEPT) Bacillus cereus (strain Q1) organic phosphonate catabolic process [GO:0019700] GO:0019700; GO:0047304 37294 FUN_031407 25 0 0 0 0 NA NA NA NA NA NA NA 37295 FUN_031401 88 79 63 26 61 ptg000023l:20650467-20658526 Q7RTR2 1.44e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37296 FUN_031401 88 79 63 26 61 ptg000023l:20650467-20658526 Q7RTR2 4.39e-39 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37297 FUN_031401 88 79 63 26 61 ptg000023l:20650467-20658526 Q7RTR2 7.6e-33 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37298 FUN_031401 88 79 63 26 61 ptg000023l:20650467-20658526 Q7RTR2 5.01e-31 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37299 FUN_031403 36 0 0 0 103 NA NA NA NA NA NA NA 37300 FUN_037763 2913 1645 665 1482 1055 NA NA NA NA NA NA NA 37301 FUN_037762 43 131 0 140 51 NA NA NA NA NA NA NA 37302 FUN_037761 2135 2192 2951 6953 5363 NA NA NA NA NA NA NA 37303 FUN_037760 330 599 472 933 548 NA NA NA NA NA NA NA 37304 FUN_037767 7171 2190 2069 2954 2002 NA NA NA NA NA NA NA 37305 FUN_037765 1669 510 287 500 386 NA NA NA NA NA NA NA 37306 FUN_037764 103 31 54 30 63 NA NA NA NA NA NA NA 37307 FUN_037769 1874 1509 1456 1179 1143 NA NA NA NA NA NA NA 37308 FUN_037768 2676 1607 1030 3035 1405 NA NA NA NA NA NA NA 37309 FUN_007322 1 0 1 0 40 NA NA NA NA NA NA NA 37310 FUN_022607 244 182 127 139 147 NA NA NA NA NA NA NA 37311 FUN_007324 22 0 28 0 47 NA NA NA NA NA NA NA 37312 FUN_007326 18 15 0 8 39 NA NA NA NA NA NA NA 37313 FUN_022601 447 211 276 384 601 NA NA NA NA NA NA NA 37314 FUN_007579 0 0 0 11 0 NA NA NA NA NA NA NA 37315 FUN_007571 24 0 23 0 28 NA NA NA NA NA NA NA 37316 FUN_007574 52 43 12 0 177 NA NA NA NA NA NA NA 37317 FUN_007576 0 0 13 25 0 NA NA NA NA NA NA NA 37318 FUN_008242 87 58 12 10 30 NA NA NA NA NA NA NA 37319 FUN_008243 66 26 22 35 64 ptg000002l:9607984-9610226 B2RX12 8.49e-55 ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multidrug resistance-associated protein 3) Mus musculus (Mouse) anion transmembrane transport [GO:0098656]; bile acid and bile salt transport [GO:0015721]; canalicular bile acid transport [GO:0015722]; leukotriene transport [GO:0071716]; transmembrane transport [GO:0055085]; xenobiotic transmembrane transport [GO:0006855]; xenobiotic transport [GO:0042908] GO:0005524; GO:0005886; GO:0006855; GO:0008559; GO:0015164; GO:0015431; GO:0015432; GO:0015721; GO:0015722; GO:0016020; GO:0016323; GO:0016887; GO:0042626; GO:0042908; GO:0042910; GO:0055085; GO:0071714; GO:0071716; GO:0098656 37320 FUN_008240 652 285 329 385 233 ptg000002l:9577472-9581406 O42574 7.08e-23 Beta-1 adrenergic receptor (Beta-1 adrenoreceptor) (Beta-1 adrenoceptor) (x-BETA1AR) Xenopus laevis (African clawed frog) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; positive regulation of GTPase activity [GO:0043547]; positive regulation of heart contraction [GO:0045823] GO:0004940; GO:0005085; GO:0005769; GO:0005886; GO:0043547; GO:0045823; GO:0071880 37321 FUN_008241 15 5 2 5 15 NA NA NA NA NA NA NA 37322 FUN_008246 770 527 483 370 323 ptg000002l:9636706-9646988 Q8VC30 2.89e-50 Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)] Mus musculus (Mouse) carbohydrate phosphorylation [GO:0046835]; cellular carbohydrate metabolic process [GO:0044262]; fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate [GO:0061624]; glycerol catabolic process [GO:0019563]; glycolytic process through fructose-1-phosphate [GO:0061625]; negative regulation of MDA-5 signaling pathway [GO:0039534]; regulation of innate immune response [GO:0045088] GO:0004371; GO:0005524; GO:0005829; GO:0019563; GO:0034012; GO:0039534; GO:0044262; GO:0045088; GO:0046835; GO:0046872; GO:0050354; GO:0061624; GO:0061625 37323 FUN_008247 194 161 57 92 139 ptg000002l:9648921-9651367 Q9WU25 7.5e-31 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) Cavia porcellus (Guinea pig) positive regulation of MAPK cascade [GO:0043410]; regulation of cardiac muscle contraction [GO:0055117]; regulation of vasoconstriction [GO:0019229] GO:0004937; GO:0005634; GO:0005737; GO:0005886; GO:0005901; GO:0019229; GO:0031965; GO:0043410; GO:0046982; GO:0055117 37324 FUN_011395 0 0 0 0 15 NA NA NA NA NA NA NA 37325 FUN_011392 10 0 0 0 6 NA NA NA NA NA NA NA 37326 FUN_005043 34 0 81 0 214 NA NA NA NA NA NA NA 37327 FUN_005042 83 144 146 203 152 ntLink_8:30374480-30376762 A2RU49 2.55e-27 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Homo sapiens (Human) lysine catabolic process [GO:0006554]; phosphorylation [GO:0016310] GO:0005759; GO:0006554; GO:0016310; GO:0019202; GO:0047992 37328 FUN_000033 56 187 66 147 396 NA NA NA NA NA NA NA 37329 FUN_005040 3043 2538 1866 1423 1480 ntLink_8:30352046-30355539 A2RU49 1.37e-28 Hydroxylysine kinase (5-hydroxy-L-lysine kinase) (EC 2.7.1.81) (Aminoglycoside phosphotransferase domain-containing protein 1) Homo sapiens (Human) lysine catabolic process [GO:0006554]; phosphorylation [GO:0016310] GO:0005759; GO:0006554; GO:0016310; GO:0019202; GO:0047992 37330 FUN_000035 9 13 85 37 260 NA NA NA NA NA NA NA 37331 FUN_005046 3 0 9 20 70 NA NA NA NA NA NA NA 37332 FUN_000037 5 5 44 25 169 NA NA NA NA NA NA NA 37333 FUN_000036 2 2 11 17 18 NA NA NA NA NA NA NA 37334 FUN_000039 1 0 4 8 9 NA NA NA NA NA NA NA 37335 FUN_000038 0 3 4 9 5 NA NA NA NA NA NA NA 37336 FUN_005049 54 329 55 25 101 NA NA NA NA NA NA NA 37337 FUN_005048 8 39 0 0 7 NA NA NA NA NA NA NA 37338 FUN_002895 0 0 10 0 22 NA NA NA NA NA NA NA 37339 FUN_002897 0 11 0 3 0 NA NA NA NA NA NA NA 37340 FUN_008796 96 139 72 293 96 NA NA NA NA NA NA NA 37341 FUN_008797 34 22 38 94 43 NA NA NA NA NA NA NA 37342 FUN_008790 357 452 301 177 249 NA NA NA NA NA NA NA 37343 FUN_008791 432 301 118 234 121 NA NA NA NA NA NA NA 37344 FUN_008792 1387 1634 819 1102 989 NA NA NA NA NA NA NA 37345 FUN_008793 3438 1425 1777 1556 1283 NA NA NA NA NA NA NA 37346 FUN_032842 0 3 6 4 2 NA NA NA NA NA NA NA 37347 FUN_008798 275 258 224 393 146 NA NA NA NA NA NA NA 37348 FUN_041575 874 329 249 439 579 ptg000035l:5424353-5427173 Q5PQJ7 3.87e-53 Tubulin-specific chaperone cofactor E-like protein (Leucine-rich repeat-containing protein 35) Rattus norvegicus (Rat) microtubule cytoskeleton organization [GO:0000226]; post-chaperonin tubulin folding pathway [GO:0007023]; tubulin complex assembly [GO:0007021] GO:0000226; GO:0005737; GO:0005856; GO:0007021; GO:0007023; GO:0043014 37349 FUN_041572 19 188 0 10 0 NA NA NA NA NA NA NA 37350 FUN_041571 11 205 0 7 2 NA NA NA NA NA NA NA 37351 FUN_041579 905 974 510 1013 905 NA NA NA NA NA NA NA 37352 FUN_009567 18 12 4 0 4 NA NA NA NA NA NA NA 37353 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37354 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37355 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37356 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 0 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37357 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 3.73e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37358 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 7.38e-170 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37359 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 2.32e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37360 FUN_032919 205 80 140 40 41 ptg000023l:37663008-37666803 Q96AY4 3.27e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37361 FUN_029929 0 0 8 0 0 NA NA NA NA NA NA NA 37362 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 3.01e-160 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37363 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 2.68e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37364 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 4.33e-149 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37365 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 1.52e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37366 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 5.71e-132 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37367 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 9.69e-122 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37368 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 2.15e-99 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37369 FUN_009560 127 43 53 153 189 ptg000004l:8536358-8548605 Q96AY4 9.34e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37370 FUN_042909 2 8 19 6 12 NA NA NA NA NA NA NA 37371 FUN_042908 1966 773 559 657 347 NA NA NA NA NA NA NA 37372 FUN_042907 220 133 117 237 202 ptg000047l:1633465-1637427 Q5R621 3.28e-48 Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) gene expression [GO:0010467]; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process [GO:0015014]; heparin metabolic process [GO:0030202]; ureteric bud formation [GO:0060676] GO:0000139; GO:0004394; GO:0010467; GO:0015014; GO:0030202; GO:0060676 37373 FUN_042906 0 0 19 0 20 NA NA NA NA NA NA NA 37374 FUN_042905 75 69 88 114 87 NA NA NA NA NA NA NA 37375 FUN_016624 68 25 11 0 55 ptg000011l:5545988-5547089 P50130 3.91e-30 D(1A) dopamine receptor (Dopamine D1 receptor) Sus scrofa (Pig) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; vasodilation [GO:0042311] GO:0004930; GO:0004952; GO:0005789; GO:0005886; GO:0007189; GO:0042311; GO:0043197 37376 FUN_016623 52 7 57 145 58 ptg000011l:5518569-5519667 Q91175 7.65e-32 Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (MAR1) Oryzias latipes (Japanese rice fish) (Japanese killifish) adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; cell-cell signaling [GO:0007267]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of heart rate by epinephrine-norepinephrine [GO:0001996]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of vasoconstriction [GO:0045907] GO:0001996; GO:0004930; GO:0004937; GO:0005886; GO:0007200; GO:0007204; GO:0007267; GO:0043410; GO:0045907; GO:0071880 37377 FUN_042902 2445 9 221 4059 3059 NA NA NA NA NA NA NA 37378 FUN_016621 1272 865 698 1216 845 NA NA NA NA NA NA NA 37379 FUN_016620 288 384 244 541 315 ptg000011l:5465576-5470629 Q96LR5 5.48e-21 Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) Homo sapiens (Human) cellular response to DNA damage stimulus [GO:0006974]; ISG15-protein conjugation [GO:0032020]; positive regulation of G1/S transition of mitotic cell cycle [GO:1900087]; protein K11-linked ubiquitination [GO:0070979]; protein K48-linked ubiquitination [GO:0070936]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209] GO:0000209; GO:0004842; GO:0005524; GO:0005634; GO:0006974; GO:0032020; GO:0042296; GO:0061631; GO:0070534; GO:0070936; GO:0070979; GO:1900087 37380 FUN_042955 58 138 126 109 204 ptg000047l:2391249-2394187 Q6PIJ6 2.43e-109 F-box only protein 38 Homo sapiens (Human) adaptive immune response [GO:0002250]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein K48-linked ubiquitination [GO:0070936]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0002250; GO:0002842; GO:0005634; GO:0005737; GO:0005829; GO:0010976; GO:0019005; GO:0031146; GO:0070936 37381 FUN_042955 58 138 126 109 204 ptg000047l:2391249-2394187 Q6PIJ6 6.09e-34 F-box only protein 38 Homo sapiens (Human) adaptive immune response [GO:0002250]; positive regulation of neuron projection development [GO:0010976]; positive regulation of T cell mediated immune response to tumor cell [GO:0002842]; protein K48-linked ubiquitination [GO:0070936]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146] GO:0002250; GO:0002842; GO:0005634; GO:0005737; GO:0005829; GO:0010976; GO:0019005; GO:0031146; GO:0070936 37382 FUN_042956 761 575 398 841 646 NA NA NA NA NA NA NA 37383 FUN_042957 1859 1653 1298 1051 1574 NA NA NA NA NA NA NA 37384 FUN_042950 260 167 249 0 334 ptg000047l:2301377-2311682 Q12933 3.94e-63 TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) Homo sapiens (Human) activation of NF-kappaB-inducing kinase activity [GO:0007250]; cellular response to nitric oxide [GO:0071732]; interleukin-17-mediated signaling pathway [GO:0097400]; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [GO:0070059]; mRNA stabilization [GO:0048255]; negative regulation of glial cell apoptotic process [GO:0034351]; negative regulation of neuron death [GO:1901215]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of extrinsic apoptotic signaling pathway [GO:2001238]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of I-kappaB phosphorylation [GO:1903721]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of tumor necrosis factor-mediated signaling pathway [GO:1903265]; programmed necrotic cell death [GO:0097300]; protein autoubiquitination [GO:0051865]; protein catabolic process [GO:0030163]; protein K63-linked ubiquitination [GO:0070534]; protein-containing complex assembly [GO:0065003]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; regulation of protein-containing complex assembly [GO:0043254]; response to endoplasmic reticulum stress [GO:0034976]; signal transduction [GO:0007165]; signal transduction involved in regulation of gene expression [GO:0023019]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000151; GO:0002637; GO:0002726; GO:0002947; GO:0004842; GO:0005164; GO:0005174; GO:0005654; GO:0005829; GO:0005938; GO:0007165; GO:0007250; GO:0008270; GO:0009898; GO:0012506; GO:0019899; GO:0019901; GO:0019903; GO:0023019; GO:0030163; GO:0030674; GO:0031435; GO:0031625; GO:0031996; GO:0032743; GO:0033209; GO:0034351; GO:0034976; GO:0035631; GO:0042802; GO:0042981; GO:0043120; GO:0043122; GO:0043123; GO:0043254; GO:0043507; GO:0044877; GO:0045121; GO:0046330; GO:0046625; GO:0048255; GO:0051091; GO:0051092; GO:0051865; GO:0065003; GO:0070059; GO:0070534; GO:0071732; GO:0097057; GO:0097300; GO:0097400; GO:1901215; GO:1903265; GO:1903721; GO:1990604; GO:2001238 37385 FUN_016671 5403 3980 3114 5420 6443 NA NA NA NA NA NA NA 37386 FUN_042952 230 202 210 3 140 NA NA NA NA NA NA NA 37387 FUN_040225 0 0 166 439 19 NA NA NA NA NA NA NA 37388 FUN_040226 0 0 0 0 21 NA NA NA NA NA NA NA 37389 FUN_040227 631 298 291 180 379 NA NA NA NA NA NA NA 37390 FUN_040220 245 166 121 101 236 NA NA NA NA NA NA NA 37391 FUN_040221 405 350 236 319 189 NA NA NA NA NA NA NA 37392 FUN_040222 544 402 289 543 547 ptg000031l:5622404-5639064 A0JPI9 1.86e-63 Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74) Rattus norvegicus (Rat) NA NA 37393 FUN_040223 2229 2484 1403 1227 761 NA NA NA NA NA NA NA 37394 FUN_040228 40 6 15 115 0 NA NA NA NA NA NA NA 37395 FUN_040229 843 330 224 239 860 NA NA NA NA NA NA NA 37396 FUN_034441 39 0 31 0 24 ptg000024l:8898550-8898928 P35067 1.65e-83 Histone H2B Acropora formosa (Staghorn coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37397 FUN_034440 0 0 0 7 16 NA NA NA NA NA NA NA 37398 FUN_034447 0 0 4 15 35 NA NA NA NA NA NA NA 37399 FUN_034446 0 0 0 20 14 NA NA NA NA NA NA NA 37400 FUN_034445 0 0 0 0 16 NA NA NA NA NA NA NA 37401 FUN_034449 0 0 13 22 0 NA NA NA NA NA NA NA 37402 FUN_010062 0 26 31 0 0 NA NA NA NA NA NA NA 37403 FUN_010066 0 0 0 0 6 NA NA NA NA NA NA NA 37404 FUN_010065 0 0 0 4 12 NA NA NA NA NA NA NA 37405 FUN_010068 0 0 0 0 93 NA NA NA NA NA NA NA 37406 FUN_002309 9 12 109 112 456 NA NA NA NA NA NA NA 37407 FUN_002308 3 3 12 15 30 NA NA NA NA NA NA NA 37408 FUN_002303 14 12 121 57 530 NA NA NA NA NA NA NA 37409 FUN_002305 9 13 118 121 550 NA NA NA NA NA NA NA 37410 FUN_002304 1 4 11 13 23 NA NA NA NA NA NA NA 37411 FUN_002307 3 5 8 20 31 NA NA NA NA NA NA NA 37412 FUN_002306 2 3 9 20 26 NA NA NA NA NA NA NA 37413 FUN_014578 0 0 18 0 0 NA NA NA NA NA NA NA 37414 FUN_014575 1649 1437 757 1375 827 NA NA NA NA NA NA NA 37415 FUN_014577 160 113 92 100 98 NA NA NA NA NA NA NA 37416 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 1.5e-85 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37417 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 2.88e-79 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37418 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 4.62e-77 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37419 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 1.02e-76 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37420 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 6.56e-75 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37421 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 7.04e-31 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37422 FUN_016758 0 0 0 74 0 ptg000011l:7042840-7049125 Q96AY4 2.78e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37423 FUN_000866 78 33 19 53 24 NA NA NA NA NA NA NA 37424 FUN_000867 135 147 10 104 72 ntLink_6:5484000-5488471 P00767 9.08e-36 Chymotrypsinogen B (EC 3.4.21.1) [Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C] Bos taurus (Bovine) digestion [GO:0007586]; proteolysis [GO:0006508] GO:0004252; GO:0005615; GO:0006508; GO:0007586 37425 FUN_000865 0 22 0 0 19 NA NA NA NA NA NA NA 37426 FUN_000862 2505 1463 1939 1658 861 NA NA NA NA NA NA NA 37427 FUN_000863 2634 2018 732 1874 925 NA NA NA NA NA NA NA 37428 FUN_000860 111 133 74 216 134 NA NA NA NA NA NA NA 37429 FUN_000861 490 344 288 657 477 NA NA NA NA NA NA NA 37430 FUN_000868 19 57 0 0 0 NA NA NA NA NA NA NA 37431 FUN_000869 0 23 0 25 26 NA NA NA NA NA NA NA 37432 FUN_026354 0 0 22 0 0 NA NA NA NA NA NA NA 37433 FUN_026355 21 0 18 107 4 NA NA NA NA NA NA NA 37434 FUN_026356 0 0 0 11 0 NA NA NA NA NA NA NA 37435 FUN_023185 2047 2686 1132 2100 1652 NA NA NA NA NA NA NA 37436 FUN_023182 0 0 11 30 0 ptg000017l:4622439-4624570 A7S4N4 1.23e-87 Probable serine incorporator Nematostella vectensis (Starlet sea anemone) phospholipid biosynthetic process [GO:0008654] GO:0005789; GO:0008654; GO:0016020 37437 FUN_026351 141 14 0 89 110 NA NA NA NA NA NA NA 37438 FUN_026353 1 0 0 6 0 NA NA NA NA NA NA NA 37439 FUN_026358 0 0 26 98 18 NA NA NA NA NA NA NA 37440 FUN_023188 19687 12952 11818 22132 14621 ptg000017l:4688086-4689337 Q3UMF9 5.22e-31 Failed axon connections homolog Mus musculus (Mouse) NA GO:0005737; GO:0016020 37441 FUN_023189 8580 5699 3624 8252 5330 NA NA NA NA NA NA NA 37442 FUN_022858 832 312 289 527 275 NA NA NA NA NA NA NA 37443 FUN_022853 260 122 77 235 249 NA NA NA NA NA NA NA 37444 FUN_022852 1583 1672 765 1459 2164 NA NA NA NA NA NA NA 37445 FUN_022851 2355 2980 2209 1636 1439 NA NA NA NA NA NA NA 37446 FUN_022850 214 132 107 159 368 NA NA NA NA NA NA NA 37447 FUN_022857 738 242 108 50 112 NA NA NA NA NA NA NA 37448 FUN_022856 2524 2858 1363 1663 1229 NA NA NA NA NA NA NA 37449 FUN_022855 530 549 208 388 260 ptg000017l:693716-698068 P0AF48 3.81e-22 UPF0047 protein YjbQ Escherichia coli (strain K12) NA NA 37450 FUN_022854 104 29 92 99 92 ptg000017l:686502-687576 Q8NDV2 5.73e-41 G-protein coupled receptor 26 Homo sapiens (Human) adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0005886; GO:0007186; GO:0007189 37451 FUN_029754 2445 1366 1328 2371 1451 NA NA NA NA NA NA NA 37452 FUN_029757 56 86 90 105 104 NA NA NA NA NA NA NA 37453 FUN_016369 1320 502 771 2128 1292 NA NA NA NA NA NA NA 37454 FUN_029750 296 391 137 1051 365 NA NA NA NA NA NA NA 37455 FUN_029753 325 171 226 252 223 ptg000023l:5296767-5297685 Q5U2Z0 1.74e-64 Zinc finger protein 367 Rattus norvegicus (Rat) regulation of transcription by RNA polymerase II [GO:0006357] GO:0000978; GO:0000981; GO:0003700; GO:0005634; GO:0005654; GO:0006357; GO:0046872 37456 FUN_016362 11545 9992 7202 9363 5307 ptg000011l:2182896-2190357 Q9D1Q6 2.74e-23 Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4) Mus musculus (Mouse) glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0003756; GO:0005788; GO:0005789; GO:0005793; GO:0006457; GO:0006986; GO:0009100; GO:0009986; GO:0034976 37457 FUN_016363 1375 701 81 640 654 ptg000011l:2195424-2203295 Q9D1Q6 8.33e-22 Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4) Mus musculus (Mouse) glycoprotein metabolic process [GO:0009100]; protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976]; response to unfolded protein [GO:0006986] GO:0003756; GO:0005788; GO:0005789; GO:0005793; GO:0006457; GO:0006986; GO:0009100; GO:0009986; GO:0034976 37458 FUN_016360 1625 1344 798 2172 1176 NA NA NA NA NA NA NA 37459 FUN_016361 2026 638 622 1041 721 NA NA NA NA NA NA NA 37460 FUN_029759 3107 4874 2425 1871 1289 ptg000023l:5398432-5401602 Q9QYK7 2.71e-23 RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669) Mus musculus (Mouse) protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0000151; GO:0005634; GO:0005769; GO:0006511; GO:0046872; GO:0051865; GO:0055037; GO:0061630 37461 FUN_016367 44 74 20 16 16 ptg000011l:2268787-2270005 Q9TUP7 6.69e-37 Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2) Canis lupus familiaris (Dog) (Canis familiaris) circadian sleep/wake cycle process [GO:0022410]; feeding behavior [GO:0007631]; G protein-coupled receptor signaling pathway [GO:0007186]; locomotion [GO:0040011]; neuropeptide signaling pathway [GO:0007218]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; regulation of circadian sleep/wake cycle, wakefulness [GO:0010840]; regulation of cytosolic calcium ion concentration [GO:0051480] GO:0004930; GO:0005886; GO:0007186; GO:0007200; GO:0007218; GO:0007631; GO:0010840; GO:0016499; GO:0022410; GO:0040011; GO:0051480 37462 FUN_016364 872 1458 1210 546 323 NA NA NA NA NA NA NA 37463 FUN_016365 90 40 29 93 40 NA NA NA NA NA NA NA 37464 FUN_015622 149 120 0 53 121 NA NA NA NA NA NA NA 37465 FUN_015623 150 141 12 25 49 NA NA NA NA NA NA NA 37466 FUN_015621 87 0 16 35 12 NA NA NA NA NA NA NA 37467 FUN_015624 6 0 0 0 35 NA NA NA NA NA NA NA 37468 FUN_015625 10 0 0 1 13 NA NA NA NA NA NA NA 37469 FUN_022585 183 155 91 17 66 NA NA NA NA NA NA NA 37470 FUN_022584 523 177 116 31 308 NA NA NA NA NA NA NA 37471 FUN_022587 0 48 0 52 37 NA NA NA NA NA NA NA 37472 FUN_022586 3779 1955 1398 2248 2357 NA NA NA NA NA NA NA 37473 FUN_022581 1672 1202 753 1059 929 NA NA NA NA NA NA NA 37474 FUN_022580 3742 3838 1996 2568 1500 ptg000016l:10909746-10915373 Q5ZMT9 4.65e-21 Insulin-induced gene 1 protein (INSIG-1) Gallus gallus (Chicken) cellular response to insulin stimulus [GO:0032869]; cholesterol biosynthetic process [GO:0006695]; SREBP signaling pathway [GO:0032933]; SREBP-SCAP complex retention in endoplasmic reticulum [GO:0036316]; sterol biosynthetic process [GO:0016126] GO:0005783; GO:0006695; GO:0008142; GO:0016126; GO:0032869; GO:0032933; GO:0032937; GO:0036316 37475 FUN_022583 62 85 91 14 10 NA NA NA NA NA NA NA 37476 FUN_022582 123 66 108 26 75 NA NA NA NA NA NA NA 37477 FUN_017709 2469 2134 1685 2692 2115 ptg000011l:13419494-13494814 P14381 1.2e-88 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37478 FUN_017708 140 306 240 372 146 ptg000011l:13404160-13405207 P0DXC0 1.63e-116 NA NA NA NA 37479 FUN_017703 0 3 0 0 7 NA NA NA NA NA NA NA 37480 FUN_017702 0 1 5 0 26 NA NA NA NA NA NA NA 37481 FUN_017707 0 0 0 0 19 NA NA NA NA NA NA NA 37482 FUN_017706 1 0 0 0 37 NA NA NA NA NA NA NA 37483 FUN_017705 0 0 0 0 23 NA NA NA NA NA NA NA 37484 FUN_023458 119 129 92 56 86 NA NA NA NA NA NA NA 37485 FUN_023459 5463 2789 2874 3918 3615 ptg000017l:7709697-7739043 Q9U2G0 2.73e-59 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) Caenorhabditis elegans mRNA splicing, via spliceosome [GO:0000398]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000388; GO:0000398; GO:0003676; GO:0003724; GO:0005524; GO:0005681; GO:0016887 37486 FUN_023459 5463 2789 2874 3918 3615 ptg000017l:7709697-7739043 Q9U2G0 2.73e-59 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) Caenorhabditis elegans mRNA splicing, via spliceosome [GO:0000398]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000388; GO:0000398; GO:0003676; GO:0003724; GO:0005524; GO:0005681; GO:0016887 37487 FUN_023459 5463 2789 2874 3918 3615 ptg000017l:7709697-7739043 Q9U2G0 6.3e-48 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) Caenorhabditis elegans mRNA splicing, via spliceosome [GO:0000398]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000388; GO:0000398; GO:0003676; GO:0003724; GO:0005524; GO:0005681; GO:0016887 37488 FUN_023459 5463 2789 2874 3918 3615 ptg000017l:7709697-7739043 Q9U2G0 4.99e-35 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) Caenorhabditis elegans mRNA splicing, via spliceosome [GO:0000398]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000388; GO:0000398; GO:0003676; GO:0003724; GO:0005524; GO:0005681; GO:0016887 37489 FUN_023459 5463 2789 2874 3918 3615 ptg000017l:7709697-7739043 Q9U2G0 4.34e-31 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) Caenorhabditis elegans mRNA splicing, via spliceosome [GO:0000398]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000388; GO:0000398; GO:0003676; GO:0003724; GO:0005524; GO:0005681; GO:0016887 37490 FUN_023459 5463 2789 2874 3918 3615 ptg000017l:7709697-7739043 Q9U2G0 7.95e-27 U5 small nuclear ribonucleoprotein 200 kDa helicase (EC 3.6.4.13) (BRR2 homolog) Caenorhabditis elegans mRNA splicing, via spliceosome [GO:0000398]; spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) [GO:0000388] GO:0000388; GO:0000398; GO:0003676; GO:0003724; GO:0005524; GO:0005681; GO:0016887 37491 FUN_028409 0 27 0 197 0 NA NA NA NA NA NA NA 37492 FUN_023450 1252 683 522 836 967 NA NA NA NA NA NA NA 37493 FUN_023451 1976 1072 850 424 737 NA NA NA NA NA NA NA 37494 FUN_028400 0 699 0 1010 8 NA NA NA NA NA NA NA 37495 FUN_028407 0 0 0 7 11 NA NA NA NA NA NA NA 37496 FUN_023456 649 292 327 1501 202 ptg000017l:7688637-7692856 Q96AY4 6.12e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37497 FUN_023456 649 292 327 1501 202 ptg000017l:7688637-7692856 Q96AY4 1.44e-121 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37498 FUN_023456 649 292 327 1501 202 ptg000017l:7688637-7692856 Q96AY4 1.85e-118 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37499 FUN_023456 649 292 327 1501 202 ptg000017l:7688637-7692856 Q96AY4 3.66e-53 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37500 FUN_023457 0 0 0 16 17 NA NA NA NA NA NA NA 37501 FUN_022329 0 0 0 0 65 NA NA NA NA NA NA NA 37502 FUN_022328 200 109 175 162 186 ptg000016l:7585883-7590703 Q8IY37 0 Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37) Homo sapiens (Human) brain development [GO:0007420]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of male gonad development [GO:2000020]; ribosome assembly [GO:0042255]; ribosome biogenesis [GO:0042254] GO:0000462; GO:0003723; GO:0003724; GO:0005524; GO:0005654; GO:0005730; GO:0005737; GO:0007420; GO:0016887; GO:0031965; GO:0034511; GO:0042254; GO:0042255; GO:2000020 37503 FUN_022328 200 109 175 162 186 ptg000016l:7585883-7590703 Q8IY37 6.94e-41 Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37) Homo sapiens (Human) brain development [GO:0007420]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; positive regulation of male gonad development [GO:2000020]; ribosome assembly [GO:0042255]; ribosome biogenesis [GO:0042254] GO:0000462; GO:0003723; GO:0003724; GO:0005524; GO:0005654; GO:0005730; GO:0005737; GO:0007420; GO:0016887; GO:0031965; GO:0034511; GO:0042254; GO:0042255; GO:2000020 37504 FUN_025119 17 0 16 6 174 NA NA NA NA NA NA NA 37505 FUN_022321 666 511 264 480 528 NA NA NA NA NA NA NA 37506 FUN_022320 502 345 152 378 192 NA NA NA NA NA NA NA 37507 FUN_022323 2785 2854 905 2410 2064 NA NA NA NA NA NA NA 37508 FUN_022322 927 1163 350 887 820 NA NA NA NA NA NA NA 37509 FUN_022324 55 196 65 4 16 NA NA NA NA NA NA NA 37510 FUN_022327 685 478 387 628 956 ptg000016l:7563949-7571835 Q5F3X4 1.01e-33 116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain protein 2) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003924; GO:0005525; GO:0005634; GO:0030623; GO:0046540; GO:0071005; GO:0071007; GO:1990904 37511 FUN_022327 685 478 387 628 956 ptg000016l:7563949-7571835 Q5F3X4 5.2e-23 116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain protein 2) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa) Gallus gallus (Chicken) mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0003924; GO:0005525; GO:0005634; GO:0030623; GO:0046540; GO:0071005; GO:0071007; GO:1990904 37512 FUN_022326 201 440 196 213 358 NA NA NA NA NA NA NA 37513 FUN_024860 53890 52424 21714 38984 22576 NA NA NA NA NA NA NA 37514 FUN_024861 74 176 34 53 148 NA NA NA NA NA NA NA 37515 FUN_024862 5134 5082 1498 2701 1795 NA NA NA NA NA NA NA 37516 FUN_024863 1341 817 969 1076 935 NA NA NA NA NA NA NA 37517 FUN_024865 2085 1810 782 1535 1707 NA NA NA NA NA NA NA 37518 FUN_024867 14 0 0 0 0 NA NA NA NA NA NA NA 37519 FUN_024869 53 59 75 112 36 ptg000018l:11830442-11835714 Q9HCU4 1.12e-26 Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0007186; GO:0016020; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060071; GO:0060271; GO:0097475; GO:0098609 37520 FUN_024869 53 59 75 112 36 ptg000018l:11830442-11835714 Q9HCU4 4.78e-22 Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) Homo sapiens (Human) cell-cell adhesion [GO:0098609]; cerebrospinal fluid secretion [GO:0033326]; cilium assembly [GO:0060271]; cilium movement [GO:0003341]; dendrite morphogenesis [GO:0048813]; G protein-coupled receptor signaling pathway [GO:0007186]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; motor neuron migration [GO:0097475]; neural plate anterior/posterior regionalization [GO:0021999]; regulation of cell-cell adhesion [GO:0022407]; regulation of DNA-templated transcription [GO:0006355]; regulation of protein localization [GO:0032880]; ventricular system development [GO:0021591]; Wnt signaling pathway [GO:0016055]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] GO:0003341; GO:0004930; GO:0005509; GO:0005737; GO:0005886; GO:0006355; GO:0007156; GO:0007186; GO:0016020; GO:0016055; GO:0021591; GO:0021999; GO:0022407; GO:0032880; GO:0033326; GO:0048813; GO:0060071; GO:0060271; GO:0097475; GO:0098609 37521 FUN_010538 0 0 0 68 0 NA NA NA NA NA NA NA 37522 FUN_019625 64 6 14 11 27 NA NA NA NA NA NA NA 37523 FUN_019623 0 3 6 0 109 NA NA NA NA NA NA NA 37524 FUN_019620 0 0 36 8 55 NA NA NA NA NA NA NA 37525 FUN_012005 1309 763 780 893 1506 NA NA NA NA NA NA NA 37526 FUN_024249 28 17 6 7 23 ptg000018l:3904454-3907355 Q8K3Z0 1.94e-30 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 37527 FUN_024524 3077 1290 1370 2858 1767 NA NA NA NA NA NA NA 37528 FUN_024244 15 23 27 89 0 ptg000018l:3875947-3879372 E9Q5R7 1.17e-46 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 37529 FUN_024240 6 52 3 18 2 NA NA NA NA NA NA NA 37530 FUN_024241 70 154 199 428 201 NA NA NA NA NA NA NA 37531 FUN_024242 191 138 28 43 323 ptg000018l:3858200-3861152 Q8K3Z0 4.43e-27 Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15) Mus musculus (Mouse) activation of immune response [GO:0002253]; biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0002815]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to muramyl dipeptide [GO:0071225]; cellular response to organic cyclic compound [GO:0071407]; cellular response to peptidoglycan [GO:0071224]; defense response [GO:0006952]; defense response to bacterium [GO:0042742]; defense response to Gram-positive bacterium [GO:0050830]; detection of bacterium [GO:0016045]; detection of biotic stimulus [GO:0009595]; detection of muramyl dipeptide [GO:0032498]; ERK1 and ERK2 cascade [GO:0070371]; establishment of localization in cell [GO:0051649]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; intracellular signal transduction [GO:0035556]; JNK cascade [GO:0007254]; maintenance of gastrointestinal epithelium [GO:0030277]; MAPK cascade [GO:0000165]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of interleukin-12 production [GO:0032695]; negative regulation of interleukin-18 production [GO:0032701]; negative regulation of interleukin-2 production [GO:0032703]; negative regulation of macrophage apoptotic process [GO:2000110]; negative regulation of macrophage cytokine production [GO:0010936]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of T cell mediated immunity [GO:0002710]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of tumor necrosis factor production [GO:0032720]; negative regulation of type II interferon production [GO:0032689]; NIK/NF-kappaB signaling [GO:0038061]; nucleotide-binding oligomerization domain containing 2 signaling pathway [GO:0070431]; pattern recognition receptor signaling pathway [GO:0002221]; peptidyl-tyrosine phosphorylation [GO:0018108]; phagocytosis [GO:0006909]; positive regulation of antibacterial peptide biosynthetic process [GO:0006963]; positive regulation of B cell activation [GO:0050871]; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria [GO:0006965]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cytokine production involved in immune response [GO:0002720]; positive regulation of cytokine production involved in inflammatory response [GO:1900017]; positive regulation of dendritic cell antigen processing and presentation [GO:0002606]; positive regulation of dendritic cell cytokine production [GO:0002732]; positive regulation of epithelial cell proliferation [GO:0050679]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of humoral immune response mediated by circulating immunoglobulin [GO:0002925]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of innate immune response [GO:0045089]; positive regulation of interleukin-1 beta production [GO:0032731]; positive regulation of interleukin-10 production [GO:0032733]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-17 production [GO:0032740]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of JNK cascade [GO:0046330]; positive regulation of macrophage cytokine production [GO:0060907]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of monocyte chemotactic protein-1 production [GO:0071639]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phagocytosis [GO:0050766]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of prostaglandin-E synthase activity [GO:2000363]; positive regulation of prostaglandin-endoperoxide synthase activity [GO:0060585]; positive regulation of protein K63-linked ubiquitination [GO:1902523]; positive regulation of protein ubiquitination [GO:0031398]; positive regulation of stress-activated MAPK cascade [GO:0032874]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of tumor necrosis factor production [GO:0032760]; positive regulation of type 2 immune response [GO:0002830]; positive regulation of xenophagy [GO:1904417]; regulation of inflammatory response [GO:0050727]; regulation of neutrophil chemotaxis [GO:0090022]; response to exogenous dsRNA [GO:0043330]; response to lipopolysaccharide [GO:0032496]; response to muramyl dipeptide [GO:0032495]; response to nutrient [GO:0007584]; response to peptidoglycan [GO:0032494]; signal transduction [GO:0007165]; stress-activated MAPK cascade [GO:0051403]; toll-like receptor 2 signaling pathway [GO:0034134]; xenophagy [GO:0098792] GO:0000165; GO:0002221; GO:0002227; GO:0002253; GO:0002606; GO:0002710; GO:0002720; GO:0002732; GO:0002815; GO:0002830; GO:0002862; GO:0002925; GO:0003779; GO:0005524; GO:0005737; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0006909; GO:0006952; GO:0006954; GO:0006963; GO:0006965; GO:0007165; GO:0007249; GO:0007254; GO:0007584; GO:0008284; GO:0009595; GO:0009986; GO:0010936; GO:0016045; GO:0016323; GO:0018108; GO:0019899; GO:0019901; GO:0030277; GO:0030544; GO:0031398; GO:0031982; GO:0032088; GO:0032494; GO:0032495; GO:0032496; GO:0032498; GO:0032500; GO:0032689; GO:0032695; GO:0032701; GO:0032703; GO:0032720; GO:0032731; GO:0032733; GO:0032735; GO:0032740; GO:0032755; GO:0032757; GO:0032760; GO:0032874; GO:0032991; GO:0034134; GO:0034136; GO:0035556; GO:0038061; GO:0038187; GO:0042742; GO:0042834; GO:0043123; GO:0043330; GO:0043406; GO:0043410; GO:0043552; GO:0044877; GO:0045087; GO:0045089; GO:0045335; GO:0045747; GO:0045944; GO:0046330; GO:0050679; GO:0050700; GO:0050727; GO:0050731; GO:0050766; GO:0050830; GO:0050871; GO:0051092; GO:0051353; GO:0051403; GO:0051649; GO:0051770; GO:0051879; GO:0060585; GO:0060907; GO:0070371; GO:0070374; GO:0070431; GO:0071222; GO:0071224; GO:0071225; GO:0071407; GO:0071639; GO:0090022; GO:0098792; GO:1900017; GO:1901224; GO:1902523; GO:1904417; GO:2000110; GO:2000363 37532 FUN_030114 8 4 0 2 7 NA NA NA NA NA NA NA 37533 FUN_030117 0 2 0 8 0 NA NA NA NA NA NA NA 37534 FUN_030116 0 0 0 0 59 NA NA NA NA NA NA NA 37535 FUN_030112 1 2 0 0 7 NA NA NA NA NA NA NA 37536 FUN_038340 37314 58028 25145 35309 24699 ptg000027l:5894155-5903345 P09102 4.09e-26 Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (Retina cognin) (R-cognin) Gallus gallus (Chicken) protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0009897; GO:0034976 37537 FUN_038340 37314 58028 25145 35309 24699 ptg000027l:5894155-5903345 P09102 2.58e-21 Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (Retina cognin) (R-cognin) Gallus gallus (Chicken) protein folding [GO:0006457]; response to endoplasmic reticulum stress [GO:0034976] GO:0003756; GO:0005783; GO:0005788; GO:0006457; GO:0009897; GO:0034976 37538 FUN_038341 2 6 76 2251 0 NA NA NA NA NA NA NA 37539 FUN_038344 766 525 555 843 704 NA NA NA NA NA NA NA 37540 FUN_038345 1605 2049 779 1657 1195 NA NA NA NA NA NA NA 37541 FUN_038346 3889 3491 2084 3931 3081 NA NA NA NA NA NA NA 37542 FUN_038347 849 771 364 901 415 NA NA NA NA NA NA NA 37543 FUN_038348 3059 993 1408 2381 1946 ptg000027l:5985059-6010469 Q7TN88 3.76e-43 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37544 FUN_038348 3059 993 1408 2381 1946 ptg000027l:5985059-6010469 Q7TN88 2.33e-26 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37545 FUN_038349 456 250 335 421 499 ptg000027l:6042659-6059181 A2A259 3.12e-43 Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog) Mus musculus (Mouse) cation transport [GO:0006812]; cellular response to acidic pH [GO:0071468]; cellular response to pH [GO:0071467]; detection of chemical stimulus involved in sensory perception of sour taste [GO:0001581]; detection of chemical stimulus involved in sensory perception of taste [GO:0050912]; detection of mechanical stimulus [GO:0050982]; inorganic cation transmembrane transport [GO:0098662]; potassium ion transmembrane transport [GO:0071805]; protein homotetramerization [GO:0051289]; protein tetramerization [GO:0051262]; response to water [GO:0009415]; sensory perception of sour taste [GO:0050915]; smoothened signaling pathway [GO:0007224]; sodium ion transmembrane transport [GO:0035725] GO:0001581; GO:0005227; GO:0005261; GO:0005262; GO:0005272; GO:0005509; GO:0005783; GO:0005829; GO:0005886; GO:0006812; GO:0007224; GO:0008092; GO:0009415; GO:0015269; GO:0015629; GO:0016020; GO:0031410; GO:0034703; GO:0034704; GO:0035725; GO:0042802; GO:0043231; GO:0043235; GO:0050912; GO:0050915; GO:0050982; GO:0051262; GO:0051289; GO:0051371; GO:0051393; GO:0060170; GO:0071467; GO:0071468; GO:0071805; GO:0097730; GO:0098662 37546 FUN_024522 0 0 0 9 0 NA NA NA NA NA NA NA 37547 FUN_039431 270 52 18 111 0 NA NA NA NA NA NA NA 37548 FUN_039433 0 0 0 30 0 ptg000030l:104280-109543 Q9D2E1 9.05e-34 Testis-specific serine/threonine-protein kinase 3 (TSK-3) (TSSK-3) (Testis-specific kinase 3) (EC 2.7.11.1) (Serine/threonine-protein kinase 22C) Mus musculus (Mouse) intracellular signal transduction [GO:0035556]; protein phosphorylation [GO:0006468]; sperm capacitation [GO:0048240]; spermatogenesis [GO:0007283] GO:0000287; GO:0004674; GO:0005524; GO:0006468; GO:0007283; GO:0035556; GO:0048240; GO:0106310 37549 FUN_039435 2015 2185 1823 1723 2427 NA NA NA NA NA NA NA 37550 FUN_039434 822 799 682 893 317 NA NA NA NA NA NA NA 37551 FUN_039437 0 0 0 18 2 NA NA NA NA NA NA NA 37552 FUN_039436 472 233 152 357 32 NA NA NA NA NA NA NA 37553 FUN_026310 74 33 48 47 15 ptg000020l:7661454-7670429 A0A1L8F5J9 4.69e-27 Glutamate receptor ionotropic, NMDA 1 (GluN1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1) Xenopus laevis (African clawed frog) response to zinc ion [GO:0010043] GO:0004972; GO:0005886; GO:0010043; GO:0017146; GO:0045211; GO:0046872 37554 FUN_023141 53 6 37 17 31 ptg000017l:4112911-4113943 E7F7V7 7.63e-22 Galanin receptor 2b Danio rerio (Zebrafish) (Brachydanio rerio) adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; neuropeptide signaling pathway [GO:0007218] GO:0004966; GO:0005886; GO:0007188; GO:0007218; GO:0008528 37555 FUN_026314 328 230 49 200 105 NA NA NA NA NA NA NA 37556 FUN_026315 175 17 17 0 6 NA NA NA NA NA NA NA 37557 FUN_026316 116 22 14 0 7 NA NA NA NA NA NA NA 37558 FUN_043038 168 177 138 209 184 NA NA NA NA NA NA NA 37559 FUN_023145 4 0 22 36 85 NA NA NA NA NA NA NA 37560 FUN_027741 349 149 41 58 41 NA NA NA NA NA NA NA 37561 FUN_015058 2144 2563 709 1212 727 NA NA NA NA NA NA NA 37562 FUN_027744 19 0 0 69 224 NA NA NA NA NA NA NA 37563 FUN_027745 64 31 27 37 122 NA NA NA NA NA NA NA 37564 FUN_027746 0 47 19 0 139 NA NA NA NA NA NA NA 37565 FUN_027747 17 9 14 5 106 NA NA NA NA NA NA NA 37566 FUN_027748 90 448 87 41 153 ptg000021l:9952092-9969032 Q9QYP1 1.92e-29 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 37567 FUN_027748 90 448 87 41 153 ptg000021l:9952092-9969032 Q9QYP1 7.35e-29 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 37568 FUN_027748 90 448 87 41 153 ptg000021l:9952092-9969032 Q9QYP1 3.06e-28 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 37569 FUN_027748 90 448 87 41 153 ptg000021l:9952092-9969032 Q9QYP1 2.48e-26 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 37570 FUN_027748 90 448 87 41 153 ptg000021l:9952092-9969032 Q9QYP1 1.54e-21 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 37571 FUN_027748 90 448 87 41 153 ptg000021l:9952092-9969032 Q9QYP1 2.46e-21 Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) Rattus norvegicus (Rat) amyloid-beta clearance by cellular catabolic process [GO:0150094]; anatomical structure development [GO:0048856]; dendrite morphogenesis [GO:0048813]; dorsal/ventral pattern formation [GO:0009953]; embryonic digit morphogenesis [GO:0042733]; embryonic limb morphogenesis [GO:0030326]; endocytosis [GO:0006897]; generation of neurons [GO:0048699]; hair follicle development [GO:0001942]; kidney development [GO:0001822]; limb development [GO:0060173]; negative regulation of axonogenesis [GO:0050771]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of ossification [GO:0030279]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of presynaptic membrane organization [GO:1901631]; positive regulation of skeletal muscle acetylcholine-gated channel clustering [GO:1904395]; postsynaptic membrane assembly [GO:0097104]; presynaptic membrane assembly [GO:0097105]; protein localization [GO:0008104]; proximal/distal pattern formation [GO:0009954]; receptor clustering [GO:0043113]; regulation of protein phosphorylation [GO:0001932]; skeletal muscle acetylcholine-gated channel clustering [GO:0071340]; synapse organization [GO:0050808]; synaptic assembly at neuromuscular junction [GO:0051124]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001932; GO:0001942; GO:0005509; GO:0005886; GO:0006897; GO:0008104; GO:0009953; GO:0009954; GO:0009986; GO:0014069; GO:0016055; GO:0030279; GO:0030326; GO:0030425; GO:0030971; GO:0031594; GO:0034185; GO:0042475; GO:0042733; GO:0042803; GO:0043025; GO:0043113; GO:0044853; GO:0048699; GO:0048813; GO:0048856; GO:0050731; GO:0050771; GO:0050808; GO:0051124; GO:0060173; GO:0071340; GO:0090090; GO:0097060; GO:0097104; GO:0097105; GO:0097110; GO:0150094; GO:1901631; GO:1904395 37572 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.57e-109 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37573 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.12e-107 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37574 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.98e-103 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37575 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.02e-103 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37576 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.92e-102 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37577 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.58e-101 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37578 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.35e-100 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37579 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 8.05e-100 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37580 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 5.09e-99 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37581 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.99e-94 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37582 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 9.92e-93 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37583 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.11e-91 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37584 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.61e-89 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37585 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 6.09e-78 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37586 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.12e-76 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37587 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 4.42e-65 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37588 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.11e-64 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37589 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.8e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37590 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.62e-62 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37591 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.1e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37592 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.44e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37593 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.8e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37594 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 5.05e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37595 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 9.06e-61 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37596 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.35e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37597 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.05e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37598 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.76e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37599 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.99e-60 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37600 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.93e-59 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37601 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.75e-59 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37602 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.47e-59 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37603 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 5.91e-57 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37604 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.85e-56 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37605 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.11e-55 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37606 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 4.42e-54 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37607 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 4.98e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37608 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 5.07e-53 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37609 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 5.97e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37610 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 9.18e-45 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37611 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 4.6e-35 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37612 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.15e-35 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37613 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.75e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37614 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 5.52e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37615 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 6.82e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37616 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.56e-34 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37617 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.44e-33 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37618 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.05e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37619 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.64e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37620 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 4.11e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37621 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 6.23e-32 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37622 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.51e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37623 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.64e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37624 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 6.27e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37625 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.43e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37626 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 7.69e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37627 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 9.42e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37628 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 9.5e-31 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37629 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.92e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37630 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 4.53e-30 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37631 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.16e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37632 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.25e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37633 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.29e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37634 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.9e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37635 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.38e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37636 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 9.84e-29 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37637 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.34e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37638 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.42e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37639 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.36e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37640 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 2.99e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37641 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 3.69e-28 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37642 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.74e-27 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37643 FUN_027749 204 525 408 145 547 ptg000021l:9973206-10053961 P10079 1.96e-26 Fibropellin-1 (Epidermal growth factor-related protein 1) (Fibropellin-I) (SpEGF I) (UEGF-1) Strongylocentrotus purpuratus (Purple sea urchin) NA GO:0005509; GO:0005615; GO:0009374; GO:0031410; GO:0032579 37644 FUN_031642 7392 8916 3243 11661 7650 ptg000023l:23789424-23807114 Q16975 1.69e-28 Calcium-independent protein kinase C (EC 2.7.11.13) (APL II) Aplysia californica (California sea hare) protein phosphorylation [GO:0006468] GO:0004698; GO:0005524; GO:0006468; GO:0016020; GO:0046872; GO:0106310 37645 FUN_031640 0 0 0 0 9 NA NA NA NA NA NA NA 37646 FUN_031646 9139 12380 7534 5115 6780 NA NA NA NA NA NA NA 37647 FUN_031647 882 583 348 702 281 NA NA NA NA NA NA NA 37648 FUN_031645 151 384 124 355 375 ptg000023l:23839523-23842124 B4DXR9 3.4e-38 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 37649 FUN_031645 151 384 124 355 375 ptg000023l:23839523-23842124 B4DXR9 1.39e-36 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 37650 FUN_031645 151 384 124 355 375 ptg000023l:23839523-23842124 B4DXR9 5.2e-30 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 37651 FUN_031645 151 384 124 355 375 ptg000023l:23839523-23842124 B4DXR9 1.98e-28 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 37652 FUN_031645 151 384 124 355 375 ptg000023l:23839523-23842124 B4DXR9 8.59e-23 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 37653 FUN_031645 151 384 124 355 375 ptg000023l:23839523-23842124 B4DXR9 4.92e-21 Zinc finger protein 732 Homo sapiens (Human) regulation of DNA-templated transcription [GO:0006355] GO:0000978; GO:0000981; GO:0005634; GO:0006355; GO:0046872 37654 FUN_031648 4661 3276 2276 3419 2829 ptg000023l:23859231-23872136 Q28654 4.35e-22 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B'-epsilon) (PP2A B subunit isoform B56-epsilon) (PP2A B subunit isoform PR61-epsilon) (PP2A B subunit isoform R5-epsilon) Oryctolagus cuniculus (Rabbit) signal transduction [GO:0007165] GO:0000159; GO:0005737; GO:0007165; GO:0019888 37655 FUN_031649 17349 12460 11640 21628 12901 NA NA NA NA NA NA NA 37656 FUN_037561 337 514 116 169 189 NA NA NA NA NA NA NA 37657 FUN_037563 617 0 0 0 2392 NA NA NA NA NA NA NA 37658 FUN_037562 299 41 80 182 198 ptg000026l:11835309-11836776 Q8CFX1 9.12e-101 GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase) (EC 1.1.1.47) (Glucose-6-phosphate dehydrogenase) (EC 1.1.1.363); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glucose metabolic process [GO:0006006]; NADP metabolic process [GO:0006739]; pentose-phosphate shunt [GO:0006098]; pentose-phosphate shunt, oxidative branch [GO:0009051]; regulation of cortisol biosynthetic process [GO:2000064] GO:0004345; GO:0005737; GO:0005739; GO:0005783; GO:0005788; GO:0005975; GO:0006006; GO:0006098; GO:0006739; GO:0009051; GO:0016529; GO:0017057; GO:0030246; GO:0043231; GO:0047934; GO:0047935; GO:0047936; GO:0050661; GO:2000064 37659 FUN_037565 153 182 106 229 189 NA NA NA NA NA NA NA 37660 FUN_037564 647 144 225 547 517 ptg000026l:11849454-11851965 O95479 0 GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase) (GDH) (EC 1.1.1.47) (Glucose-6-phosphate dehydrogenase) (EC 1.1.1.363); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] Homo sapiens (Human) glucose metabolic process [GO:0006006]; pentose-phosphate shunt, oxidative branch [GO:0009051]; regulation of cortisol biosynthetic process [GO:2000064]; response to alcohol [GO:0097305]; response to nutrient levels [GO:0031667] GO:0004345; GO:0005739; GO:0005783; GO:0005788; GO:0006006; GO:0009051; GO:0017057; GO:0030246; GO:0031667; GO:0047934; GO:0047935; GO:0047936; GO:0050661; GO:0097305; GO:2000064 37661 FUN_037567 5353 11759 5154 9113 4808 NA NA NA NA NA NA NA 37662 FUN_037566 8096 5060 5055 7890 7082 NA NA NA NA NA NA NA 37663 FUN_037569 556 322 294 584 195 NA NA NA NA NA NA NA 37664 FUN_037568 1477 745 653 1124 959 NA NA NA NA NA NA NA 37665 FUN_006791 1150 535 448 89 461 ptg000001l:16613939-16680732 P10394 7.48e-147 Retrovirus-related Pol polyprotein from transposon 412 [Includes: Protease (EC 3.4.23.-); Reverse transcriptase (EC 2.7.7.49); Endonuclease] Drosophila melanogaster (Fruit fly) DNA integration [GO:0015074]; proteolysis [GO:0006508] GO:0003676; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0006508; GO:0015074; GO:0042575 37666 FUN_031394 6 5 0 62 68 NA NA NA NA NA NA NA 37667 FUN_031396 254 330 215 58 278 ptg000023l:20578298-20590972 Q7RTR2 9.06e-56 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37668 FUN_031396 254 330 215 58 278 ptg000023l:20578298-20590972 Q7RTR2 6.75e-53 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37669 FUN_031396 254 330 215 58 278 ptg000023l:20578298-20590972 Q7RTR2 5.19e-52 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37670 FUN_031396 254 330 215 58 278 ptg000023l:20578298-20590972 Q7RTR2 3.46e-28 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37671 FUN_031392 156 222 149 35 339 ptg000023l:20504246-20523908 Q7RTR2 3.48e-63 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37672 FUN_031392 156 222 149 35 339 ptg000023l:20504246-20523908 Q7RTR2 4.65e-61 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37673 FUN_031392 156 222 149 35 339 ptg000023l:20504246-20523908 Q7RTR2 8.83e-58 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37674 FUN_031392 156 222 149 35 339 ptg000023l:20504246-20523908 Q7RTR2 1.13e-44 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 37675 FUN_031393 0 0 0 0 36 NA NA NA NA NA NA NA 37676 FUN_031398 0 71 0 0 10 NA NA NA NA NA NA NA 37677 FUN_031399 0 145 0 0 10 NA NA NA NA NA NA NA 37678 FUN_020902 0 0 0 0 9 NA NA NA NA NA NA NA 37679 FUN_006797 2910 2342 1534 2941 2009 NA NA NA NA NA NA NA 37680 FUN_018496 33 70 58 124 68 NA NA NA NA NA NA NA 37681 FUN_034068 0 4 0 1108 1417 NA NA NA NA NA NA NA 37682 FUN_026831 57 5 1 0 0 NA NA NA NA NA NA NA 37683 FUN_026833 48 33 114 0 4 NA NA NA NA NA NA NA 37684 FUN_026832 207 0 0 0 0 NA NA NA NA NA NA NA 37685 FUN_026834 0 0 0 0 23 NA NA NA NA NA NA NA 37686 FUN_026836 0 12 11 0 45 NA NA NA NA NA NA NA 37687 FUN_026839 0 0 0 0 15 NA NA NA NA NA NA NA 37688 FUN_026838 2 0 0 17 8 NA NA NA NA NA NA NA 37689 FUN_034067 464 812 343 834 705 ptg000024l:4478202-4502973 B5DF45 1.79e-40 TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6) Rattus norvegicus (Rat) activation of NF-kappaB-inducing kinase activity [GO:0007250]; activation of protein kinase activity [GO:0032147]; animal organ morphogenesis [GO:0009887]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; bone remodeling [GO:0046849]; bone resorption [GO:0045453]; cell development [GO:0048468]; cellular response to cytokine stimulus [GO:0071345]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to lipopolysaccharide [GO:0071222]; cytokine-mediated signaling pathway [GO:0019221]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; immune response [GO:0006955]; in utero embryonic development [GO:0001701]; interleukin-1-mediated signaling pathway [GO:0070498]; interleukin-17-mediated signaling pathway [GO:0097400]; JNK cascade [GO:0007254]; myeloid dendritic cell differentiation [GO:0043011]; negative regulation of DNA-templated transcription [GO:0045892]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neural tube closure [GO:0001843]; odontogenesis of dentin-containing tooth [GO:0042475]; ossification [GO:0001503]; osteoclast differentiation [GO:0030316]; positive regulation of DNA-binding transcription factor activity [GO:0051091]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-12 production [GO:0032735]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of interleukin-6 production [GO:0032755]; positive regulation of JNK cascade [GO:0046330]; positive regulation of JUN kinase activity [GO:0043507]; positive regulation of leukocyte adhesion to vascular endothelial cell [GO:1904996]; positive regulation of lipopolysaccharide-mediated signaling pathway [GO:0031666]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; positive regulation of osteoclast differentiation [GO:0045672]; positive regulation of smooth muscle cell proliferation [GO:0048661]; positive regulation of T cell cytokine production [GO:0002726]; positive regulation of T cell proliferation [GO:0042102]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of transcription regulatory region DNA binding [GO:2000679]; protein autoubiquitination [GO:0051865]; protein K63-linked ubiquitination [GO:0070534]; protein polyubiquitination [GO:0000209]; protein ubiquitination [GO:0016567]; regulation of apoptotic process [GO:0042981]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of immunoglobulin production [GO:0002637]; response to interleukin-1 [GO:0070555]; response to ischemia [GO:0002931]; signal transduction [GO:0007165]; T cell receptor signaling pathway [GO:0050852]; T-helper 1 type immune response [GO:0042088]; tumor necrosis factor-mediated signaling pathway [GO:0033209] GO:0000122; GO:0000209; GO:0001503; GO:0001701; GO:0001843; GO:0002637; GO:0002726; GO:0002931; GO:0004842; GO:0005164; GO:0005634; GO:0005737; GO:0005811; GO:0005829; GO:0005886; GO:0005938; GO:0006955; GO:0006974; GO:0007165; GO:0007249; GO:0007250; GO:0007254; GO:0008270; GO:0009887; GO:0009898; GO:0016567; GO:0019221; GO:0019886; GO:0019901; GO:0030316; GO:0031435; GO:0031624; GO:0031625; GO:0031666; GO:0031996; GO:0032147; GO:0032735; GO:0032743; GO:0032755; GO:0032813; GO:0032991; GO:0033209; GO:0035631; GO:0042088; GO:0042102; GO:0042475; GO:0042802; GO:0042826; GO:0042981; GO:0043011; GO:0043122; GO:0043123; GO:0043422; GO:0043507; GO:0045453; GO:0045672; GO:0045892; GO:0045944; GO:0046330; GO:0046849; GO:0047485; GO:0048468; GO:0048471; GO:0048661; GO:0050852; GO:0051091; GO:0051092; GO:0051865; GO:0061630; GO:0070498; GO:0070534; GO:0070555; GO:0071222; GO:0071345; GO:0097400; GO:1901224; GO:1904996; GO:2000679 37690 FUN_018499 133 181 25 77 11 ptg000012l:10103694-10105537 P20664 2.14e-24 DNA primase small subunit (EC 2.7.7.102) (DNA primase 49 kDa subunit) (p49) Mus musculus (Mouse) DNA replication initiation [GO:0006270]; DNA replication, synthesis of RNA primer [GO:0006269] GO:0000287; GO:0003896; GO:0005658; GO:0006269; GO:0006270; GO:0008270; GO:0032553 37691 FUN_015056 13104 12619 7238 10242 5163 ptg000009l:5692786-5696241 B2RZ78 9.2e-27 Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29) Rattus norvegicus (Rat) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005769; GO:0005770; GO:0005829; GO:0006886; GO:0010008; GO:0030904; GO:0030906; GO:0032456; GO:0042147; GO:0046872 37692 FUN_015056 13104 12619 7238 10242 5163 ptg000009l:5692786-5696241 B2RZ78 9.2e-27 Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29) Rattus norvegicus (Rat) endocytic recycling [GO:0032456]; intracellular protein transport [GO:0006886]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005768; GO:0005769; GO:0005770; GO:0005829; GO:0006886; GO:0010008; GO:0030904; GO:0030906; GO:0032456; GO:0042147; GO:0046872 37693 FUN_005647 0 0 4 0 6 NA NA NA NA NA NA NA 37694 FUN_015051 1294 1136 665 1049 782 ptg000009l:5643197-5643626 P83877 9.51e-99 Thioredoxin-like protein 4A (DIM1 protein homolog) (Spliceosomal U5 snRNP-specific 15 kDa protein) (Thioredoxin-like U5 snRNP protein U5-15kD) Mus musculus (Mouse) cell cycle [GO:0007049]; cell division [GO:0051301]; mRNA splicing, via spliceosome [GO:0000398] GO:0000398; GO:0005634; GO:0005654; GO:0005681; GO:0005682; GO:0005737; GO:0005829; GO:0007049; GO:0031965; GO:0046540; GO:0051301; GO:0071005 37695 FUN_043030 465 605 253 241 401 ptg000047l:3150086-3153184 Q0P5A6 1.3e-27 26S proteasome non-ATPase regulatory subunit 5 Bos taurus (Bovine) proteasome assembly [GO:0043248] GO:0022624; GO:0043248 37696 FUN_043030 465 605 253 241 401 ptg000047l:3150086-3153184 Q0P5A6 7.5e-23 26S proteasome non-ATPase regulatory subunit 5 Bos taurus (Bovine) proteasome assembly [GO:0043248] GO:0022624; GO:0043248 37697 FUN_005530 132 70 86 60 79 NA NA NA NA NA NA NA 37698 FUN_001228 1148 396 874 1374 761 ntLink_6:10005919-10012417 Q5RF48 3.5e-24 Methanethiol oxidase (MTO) (EC 1.8.3.4) (Selenium-binding protein 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549 37699 FUN_001228 1148 396 874 1374 761 ntLink_6:10005919-10012417 Q5RF48 1.25e-23 Methanethiol oxidase (MTO) (EC 1.8.3.4) (Selenium-binding protein 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549 37700 FUN_001228 1148 396 874 1374 761 ntLink_6:10005919-10012417 Q5RF48 1.25e-23 Methanethiol oxidase (MTO) (EC 1.8.3.4) (Selenium-binding protein 1) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) protein transport [GO:0015031] GO:0005634; GO:0005829; GO:0008430; GO:0015031; GO:0016020; GO:0018549 37701 FUN_030938 0 0 0 0 8 NA NA NA NA NA NA NA 37702 FUN_001222 0 0 22 17 10 ntLink_6:9939130-9940645 P07477 6.68e-29 Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-I) (Beta-trypsin) (Cationic trypsinogen) (Pretrypsinogen I) (Trypsin I) (Trypsin-1) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2] Homo sapiens (Human) digestion [GO:0007586]; extracellular matrix disassembly [GO:0022617]; proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005615; GO:0006508; GO:0007586; GO:0022617; GO:0046872; GO:0062023; GO:0072562 37703 FUN_001221 23928 7407 3253 17267 1140 NA NA NA NA NA NA NA 37704 FUN_001227 1686 1144 861 1522 1492 NA NA NA NA NA NA NA 37705 FUN_001226 106 108 103 80 82 NA NA NA NA NA NA NA 37706 FUN_001224 122 131 35 44 51 NA NA NA NA NA NA NA 37707 FUN_025878 1464 1571 1002 1350 870 ptg000020l:1554060-1559048 A5GFY8 7.05e-28 D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) Sus scrofa (Pig) L-serine biosynthetic process [GO:0006564] GO:0004617; GO:0006564; GO:0030060; GO:0051287 37708 FUN_025879 426 387 292 321 244 ptg000020l:1560312-1562849 Q6NXT1 5.12e-36 Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein) Homo sapiens (Human) nucleocytoplasmic transport [GO:0006913]; positive regulation of erythrocyte differentiation [GO:0045648]; regulation of intracellular signal transduction [GO:1902531]; regulation of protein kinase activity [GO:0045859] GO:0005634; GO:0005737; GO:0006913; GO:0019887; GO:0030496; GO:0044877; GO:0045648; GO:0045859; GO:1902531 37709 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 2.24e-47 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37710 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 5.79e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37711 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 9.68e-46 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37712 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 1.53e-45 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37713 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 2.44e-43 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37714 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 1.3e-25 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37715 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 2.48e-25 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37716 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 4.56e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37717 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 5.09e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37718 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 6.89e-24 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37719 FUN_028447 6678 7882 8369 13206 8715 ptg000021l:20069078-20083106 Q95218 1.52e-23 Deleted in malignant brain tumors 1 protein (Hensin) Oryctolagus cuniculus (Rabbit) cell differentiation [GO:0030154]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; protein transport [GO:0015031] GO:0005044; GO:0005576; GO:0015031; GO:0019898; GO:0030154; GO:0035375; GO:0042589; GO:0050829; GO:0050830 37720 FUN_025870 210 566 122 422 228 ptg000020l:1468058-1483588 E9Q5R7 2.95e-49 NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (PYPAF7) Mus musculus (Mouse) cellular response to cytokine stimulus [GO:0071345]; dendritic cell migration [GO:0036336]; ERK1 and ERK2 cascade [GO:0070371]; negative regulation of cytokine production [GO:0001818]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of interleukin-1 production [GO:0032692]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of signal transduction [GO:0009968]; negative regulation of Toll signaling pathway [GO:0045751]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of MHC class I biosynthetic process [GO:0045345]; positive regulation of NIK/NF-kappaB signaling [GO:1901224]; regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043281]; regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043122]; regulation of inflammatory response [GO:0050727] GO:0001818; GO:0005524; GO:0005737; GO:0009968; GO:0031953; GO:0032088; GO:0032692; GO:0032715; GO:0036336; GO:0038061; GO:0043122; GO:0043124; GO:0043281; GO:0045345; GO:0045751; GO:0050727; GO:0050728; GO:0070371; GO:0070373; GO:0071345; GO:1901223; GO:1901224 37721 FUN_025871 412 763 656 671 342 NA NA NA NA NA NA NA 37722 FUN_025872 363 357 216 471 504 NA NA NA NA NA NA NA 37723 FUN_025873 1730 699 562 1165 1089 NA NA NA NA NA NA NA 37724 FUN_025874 18 0 0 191 247 NA NA NA NA NA NA NA 37725 FUN_025875 5711 3481 2922 3493 2431 NA NA NA NA NA NA NA 37726 FUN_025876 56 21 58 79 36 NA NA NA NA NA NA NA 37727 FUN_025877 1344 2073 1097 874 1126 NA NA NA NA NA NA NA 37728 FUN_028445 5173 4815 1414 8884 8129 NA NA NA NA NA NA NA 37729 FUN_016116 117 95 68 68 145 ptg000010l:1800389-1806231 Q5R1P3 1.05e-28 Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) Canis lupus familiaris (Dog) (Canis familiaris) calcium ion transmembrane import into cytosol [GO:0097553]; excitatory postsynaptic potential [GO:0060079]; long-term synaptic potentiation [GO:0060291]; protein heterotetramerization [GO:0051290]; regulation of neuronal synaptic plasticity [GO:0048168] GO:0004972; GO:0005764; GO:0005770; GO:0005856; GO:0005886; GO:0008270; GO:0014069; GO:0015276; GO:0016595; GO:0017146; GO:0022849; GO:0038023; GO:0048168; GO:0051290; GO:0060079; GO:0060291; GO:0097553; GO:0098839 37730 FUN_028443 21 2 0 9 18 NA NA NA NA NA NA NA 37731 FUN_023492 7 7 0 0 9 NA NA NA NA NA NA NA 37732 FUN_023493 384 160 96 189 68 ptg000017l:8183194-8184124 Q6DHN0 1.6e-32 Transmembrane protein 53 Danio rerio (Zebrafish) (Brachydanio rerio) negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of ossification [GO:0030279]; negative regulation of osteoblast differentiation [GO:0045668]; regulation of nucleocytoplasmic transport [GO:0046822] GO:0005640; GO:0030279; GO:0030514; GO:0031965; GO:0045668; GO:0046822 37733 FUN_028429 0 0 0 6 0 NA NA NA NA NA NA NA 37734 FUN_018236 139 41 116 29 248 NA NA NA NA NA NA NA 37735 FUN_018237 124 49 23 444 182 NA NA NA NA NA NA NA 37736 FUN_018234 42 139 0 169 134 NA NA NA NA NA NA NA 37737 FUN_018232 0 81 28 227 95 NA NA NA NA NA NA NA 37738 FUN_007978 70 34 46 42 171 NA NA NA NA NA NA NA 37739 FUN_018230 56 84 28 139 152 NA NA NA NA NA NA NA 37740 FUN_007975 717 403 477 658 730 NA NA NA NA NA NA NA 37741 FUN_007974 21 4 8 18 18 NA NA NA NA NA NA NA 37742 FUN_007977 704 1009 619 669 715 NA NA NA NA NA NA NA 37743 FUN_007976 3041 1302 1161 2077 2005 NA NA NA NA NA NA NA 37744 FUN_007971 0 19 13 5 41 NA NA NA NA NA NA NA 37745 FUN_007970 20 0 15 4 243 ptg000002l:6671042-6672847 Q9R045 4.01e-31 Angiopoietin-related protein 2 (Angiopoietin-like protein 2) Mus musculus (Mouse) NA GO:0005102; GO:0005615; GO:0062023 37746 FUN_018238 120 0 29 322 181 NA NA NA NA NA NA NA 37747 FUN_018239 0 0 0 29 0 NA NA NA NA NA NA NA 37748 FUN_008095 1387 993 574 1056 657 NA NA NA NA NA NA NA 37749 FUN_034139 0 27 0 16 29 NA NA NA NA NA NA NA 37750 FUN_034138 22 37 24 23 30 NA NA NA NA NA NA NA 37751 FUN_034011 1526 1217 1028 1290 864 NA NA NA NA NA NA NA 37752 FUN_034133 294 545 0 427 384 ptg000024l:5243901-5249673 A0A2B4RP11 2.73e-26 NA NA NA NA 37753 FUN_034133 294 545 0 427 384 ptg000024l:5243901-5249673 A0A2B4RP11 1.5e-22 NA NA NA NA 37754 FUN_034132 0 243 0 306 343 ptg000024l:5231795-5236366 A0A2B4RP11 4.04e-52 NA NA NA NA 37755 FUN_034131 412 479 275 375 269 NA NA NA NA NA NA NA 37756 FUN_034130 669 714 567 744 480 NA NA NA NA NA NA NA 37757 FUN_034137 61 218 44 239 88 NA NA NA NA NA NA NA 37758 FUN_034136 332 71 173 105 190 NA NA NA NA NA NA NA 37759 FUN_034135 1007 829 474 1029 735 NA NA NA NA NA NA NA 37760 FUN_034134 165 85 49 169 94 NA NA NA NA NA NA NA 37761 FUN_018554 13 0 0 0 4 NA NA NA NA NA NA NA 37762 FUN_031201 0 10 8 18 3 NA NA NA NA NA NA NA 37763 FUN_013879 0 658 43 73 93 NA NA NA NA NA NA NA 37764 FUN_043448 1309 591 555 743 633 ptg000047l:8695654-8709883 Q3UNX5 6.42e-48 Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog) Mus musculus (Mouse) acyl-CoA metabolic process [GO:0006637]; fatty acid biosynthetic process [GO:0006633] GO:0004321; GO:0005524; GO:0005739; GO:0005759; GO:0006633; GO:0006637; GO:0015645; GO:0018729; GO:0043759; GO:0046872; GO:0047760; GO:0050218 37765 FUN_013878 1625 355 323 2173 1157 NA NA NA NA NA NA NA 37766 FUN_043444 154 206 88 233 14 NA NA NA NA NA NA NA 37767 FUN_043447 2040 994 1292 2013 2192 NA NA NA NA NA NA NA 37768 FUN_043446 133 18 36 234 130 NA NA NA NA NA NA NA 37769 FUN_043441 442 312 112 289 174 NA NA NA NA NA NA NA 37770 FUN_043440 2777 2427 3251 3582 1400 NA NA NA NA NA NA NA 37771 FUN_043443 100 181 79 192 30 NA NA NA NA NA NA NA 37772 FUN_043442 102 59 48 65 44 NA NA NA NA NA NA NA 37773 FUN_030258 4 0 4 0 17 ptg000023l:10474734-10475497 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37774 FUN_030252 3 0 4 0 14 ptg000023l:10462579-10463342 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37775 FUN_030250 5 0 3 0 19 ptg000023l:10458527-10459290 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37776 FUN_030256 5 0 2 0 19 ptg000023l:10470682-10471445 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37777 FUN_030254 3 0 3 0 18 ptg000023l:10466630-10467393 P84239 4.03e-93 Histone H3 Urechis caupo (Innkeeper worm) (Spoonworm) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37778 FUN_041357 0 0 0 0 30 NA NA NA NA NA NA NA 37779 FUN_041354 18 50 64 132 51 NA NA NA NA NA NA NA 37780 FUN_013273 132 17 131 117 197 NA NA NA NA NA NA NA 37781 FUN_013272 67 30 0 0 24 NA NA NA NA NA NA NA 37782 FUN_002228 0 0 0 0 13 NA NA NA NA NA NA NA 37783 FUN_002227 172 305 45 56 24 NA NA NA NA NA NA NA 37784 FUN_002225 0 0 0 0 8 NA NA NA NA NA NA NA 37785 FUN_019817 0 0 0 0 6 NA NA NA NA NA NA NA 37786 FUN_041592 281 450 498 536 211 NA NA NA NA NA NA NA 37787 FUN_013874 40 0 20 0 36 NA NA NA NA NA NA NA 37788 FUN_014526 68 117 61 79 218 NA NA NA NA NA NA NA 37789 FUN_037719 0 0 0 11 0 ptg000026l:12749367-12751706 Q9UHC6 5.71e-21 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 37790 FUN_014527 1501 808 710 1086 803 ptg000009l:948066-952397 Q9QZ67 8.4e-32 Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1) Mus musculus (Mouse) cellular response to starvation [GO:0009267]; DNA damage response, signal transduction by p53 class mediator [GO:0030330]; DNA methylation [GO:0006306]; G2/M transition of mitotic cell cycle [GO:0000086]; heterochromatin formation [GO:0031507]; negative regulation of gene expression, epigenetic [GO:0045814]; peptidyl-threonine dephosphorylation [GO:0035970]; response to bacterium [GO:0009617] GO:0000086; GO:0004722; GO:0005634; GO:0005654; GO:0005730; GO:0005829; GO:0006306; GO:0009267; GO:0009617; GO:0017018; GO:0030330; GO:0031507; GO:0035970; GO:0045814; GO:0046872; GO:0051019 37791 FUN_041235 116 350 375 915 61 NA NA NA NA NA NA NA 37792 FUN_023285 0 0 475 648 375 ptg000017l:5917067-5928887 A0A2B4SJA1 2.11e-74 NA NA NA NA 37793 FUN_013755 49 243 131 49 263 NA NA NA NA NA NA NA 37794 FUN_014528 365 622 377 475 331 ptg000009l:953172-958602 P56839 5.05e-60 Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9) Mytilus edulis (Blue mussel) organic phosphonate biosynthetic process [GO:0032923] GO:0032923; GO:0046872; GO:0050188 37795 FUN_014528 365 622 377 475 331 ptg000009l:953172-958602 P56839 2.11e-31 Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9) Mytilus edulis (Blue mussel) organic phosphonate biosynthetic process [GO:0032923] GO:0032923; GO:0046872; GO:0050188 37796 FUN_014528 365 622 377 475 331 ptg000009l:953172-958602 P56839 3.82e-21 Phosphoenolpyruvate phosphomutase (PEP mutase) (PEP phosphomutase) (Phosphoenolpyruvate mutase) (EC 5.4.2.9) Mytilus edulis (Blue mussel) organic phosphonate biosynthetic process [GO:0032923] GO:0032923; GO:0046872; GO:0050188 37797 FUN_013757 27 32 0 33 38 NA NA NA NA NA NA NA 37798 FUN_004569 2606 1307 1153 2434 2527 NA NA NA NA NA NA NA 37799 FUN_023280 0 0 2 0 29 NA NA NA NA NA NA NA 37800 FUN_042710 57 1 92 1 167 ptg000040l:213799-215168 Q6LAF1 1.82e-48 Histone H4 Dendronephthya klunzingeri (Klunzinger's soft coral) NA GO:0000786; GO:0003677; GO:0005634; GO:0030527; GO:0046982 37801 FUN_023282 7 438 133 123 45 NA NA NA NA NA NA NA 37802 FUN_040405 38 64 0 661 382 NA NA NA NA NA NA NA 37803 FUN_040406 439 495 279 747 475 ptg000031l:7940001-7961043 P14381 4.47e-78 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37804 FUN_040406 439 495 279 747 475 ptg000031l:7940001-7961043 P14381 4.47e-78 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37805 FUN_040407 20 199 0 1314 554 NA NA NA NA NA NA NA 37806 FUN_040400 3 229 0 0 0 NA NA NA NA NA NA NA 37807 FUN_040401 0 146 0 0 0 NA NA NA NA NA NA NA 37808 FUN_040402 3643 2646 2110 4452 3443 NA NA NA NA NA NA NA 37809 FUN_040403 1580 1371 712 2395 1094 NA NA NA NA NA NA NA 37810 FUN_040408 1754 589 436 2886 1728 NA NA NA NA NA NA NA 37811 FUN_040409 89 76 26 216 176 NA NA NA NA NA NA NA 37812 FUN_001588 3167 2363 1672 3583 3531 NA NA NA NA NA NA NA 37813 FUN_001589 774 498 380 881 568 NA NA NA NA NA NA NA 37814 FUN_023516 96 140 27 142 79 NA NA NA NA NA NA NA 37815 FUN_029826 12 0 0 0 0 NA NA NA NA NA NA NA 37816 FUN_029825 42 0 38 11 46 NA NA NA NA NA NA NA 37817 FUN_029824 0 0 11 5 30 NA NA NA NA NA NA NA 37818 FUN_029828 0 0 0 0 19 NA NA NA NA NA NA NA 37819 FUN_043337 652 0 0 16 0 NA NA NA NA NA NA NA 37820 FUN_043336 65 0 1 2 0 NA NA NA NA NA NA NA 37821 FUN_007177 2571 1576 755 2024 3084 NA NA NA NA NA NA NA 37822 FUN_007176 1378 1180 766 873 552 NA NA NA NA NA NA NA 37823 FUN_043171 1233 817 147 1051 864 NA NA NA NA NA NA NA 37824 FUN_007171 514 374 303 595 673 ptg000001l:21247433-21254253 Q7ZW24 0 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (EC 2.4.1.131) (Asparagine-linked glycosylation protein 11 homolog) (Glycolipid 2-alpha-mannosyltransferase) Danio rerio (Zebrafish) (Brachydanio rerio) oligosaccharide-lipid intermediate biosynthetic process [GO:0006490]; protein N-linked glycosylation [GO:0006487] GO:0004377; GO:0005789; GO:0006487; GO:0006490; GO:0016020 37825 FUN_043332 1070 3 0 3 0 NA NA NA NA NA NA NA 37826 FUN_032492 0 132 42 119 249 NA NA NA NA NA NA NA 37827 FUN_032493 636 765 207 545 733 NA NA NA NA NA NA NA 37828 FUN_032490 12 173 35 74 46 NA NA NA NA NA NA NA 37829 FUN_032491 26 100 71 155 22 NA NA NA NA NA NA NA 37830 FUN_032496 0 94 310 285 725 NA NA NA NA NA NA NA 37831 FUN_032497 0 107 57 110 161 NA NA NA NA NA NA NA 37832 FUN_032494 916 333 257 402 397 NA NA NA NA NA NA NA 37833 FUN_032495 171 140 186 354 577 NA NA NA NA NA NA NA 37834 FUN_032498 29 134 0 214 304 NA NA NA NA NA NA NA 37835 FUN_032499 464 759 117 1616 1775 NA NA NA NA NA NA NA 37836 FUN_043170 6 8 5 8 27 NA NA NA NA NA NA NA 37837 FUN_008453 1920 1775 843 1618 1507 ptg000002l:11723538-11724460 D3YXG0 9.37e-56 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37838 FUN_008453 1920 1775 843 1618 1507 ptg000002l:11723538-11724460 D3YXG0 1.78e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37839 FUN_008453 1920 1775 843 1618 1507 ptg000002l:11723538-11724460 D3YXG0 6.27e-52 Hemicentin-1 (Fibulin-6) (FIBL-6) Mus musculus (Mouse) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617] GO:0005509; GO:0005576; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0009617; GO:0030054; GO:0032154; GO:0051301; GO:0062023; GO:0071711; GO:0090527 37840 FUN_008451 295 94 114 98 80 NA NA NA NA NA NA NA 37841 FUN_008450 4837 5631 3314 7291 5461 NA NA NA NA NA NA NA 37842 FUN_008457 88 4 149 15 264 NA NA NA NA NA NA NA 37843 FUN_008456 1220 293 711 1190 1106 ptg000002l:11757112-11778201 Q7Z442 4.04e-38 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Homo sapiens (Human) detection of mechanical stimulus [GO:0050982] GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37844 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 3.55e-52 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37845 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 3.55e-52 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37846 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 3.55e-52 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37847 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 8.66e-32 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37848 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 1.52e-25 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37849 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 8.75e-24 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37850 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 1.06e-21 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37851 FUN_008455 5271 4702 3126 6351 6097 ptg000002l:11726797-11755784 Q8BQM8 1.46e-21 Echinoderm microtubule-associated protein-like 5 (EMAP-5) Mus musculus (Mouse) NA GO:0005737; GO:0005874; GO:0008017 37852 FUN_008454 0 18 0 16 12 NA NA NA NA NA NA NA 37853 FUN_008459 1017 359 662 934 875 ptg000002l:11832463-11841377 Q7TN88 5.34e-42 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37854 FUN_008459 1017 359 662 934 875 ptg000002l:11832463-11841377 Q7TN88 5.84e-27 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37855 FUN_008458 162 87 96 162 209 NA NA NA NA NA NA NA 37856 FUN_000206 2431 2699 1809 2104 677 NA NA NA NA NA NA NA 37857 FUN_013913 10 0 0 7 0 NA NA NA NA NA NA NA 37858 FUN_000204 1267 1264 727 1698 650 NA NA NA NA NA NA NA 37859 FUN_000205 96 60 32 14 37 NA NA NA NA NA NA NA 37860 FUN_013919 0 0 0 0 6 NA NA NA NA NA NA NA 37861 FUN_000208 533 239 193 368 935 NA NA NA NA NA NA NA 37862 FUN_000209 777 1878 302 1014 17 ntLink_6:291801-295721 B8V7S0 9.41e-35 CUB and peptidase domain-containing protein 1 Acropora millepora (Staghorn coral) (Heteropora millepora) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0006508 37863 FUN_043172 292 222 72 296 364 NA NA NA NA NA NA NA 37864 FUN_044174 6 0 8 7 18 NA NA NA NA NA NA NA 37865 FUN_006888 68 176 61 127 176 ptg000001l:17975834-17985292 Q7TN88 8.4e-49 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37866 FUN_006888 68 176 61 127 176 ptg000001l:17975834-17985292 Q7TN88 4.42e-38 Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2) Mus musculus (Mouse) detection of mechanical stimulus [GO:0050982] GO:0001965; GO:0005262; GO:0005509; GO:0016020; GO:0030246; GO:0050982 37867 FUN_014215 10 3 9 0 3 NA NA NA NA NA NA NA 37868 FUN_044177 6 14 84 32 183 NA NA NA NA NA NA NA 37869 FUN_014211 0 2 0 0 11 NA NA NA NA NA NA NA 37870 FUN_029175 2751 1534 1737 2269 2012 NA NA NA NA NA NA NA 37871 FUN_029174 3731 2990 1771 2359 1859 NA NA NA NA NA NA NA 37872 FUN_016988 1777 1359 1295 1777 1023 ptg000011l:9925296-9943521 Q8CJ69 2.15e-25 BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2) Mus musculus (Mouse) blood vessel development [GO:0001568]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; BMP signaling pathway [GO:0030509]; common-partner SMAD protein phosphorylation [GO:0007182]; endothelial cell activation [GO:0042118]; inner ear development [GO:0048839]; negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell migration [GO:0010594]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization [GO:0032880]; ureteric bud development [GO:0001657] GO:0001568; GO:0001657; GO:0002043; GO:0005576; GO:0005615; GO:0007182; GO:0010594; GO:0030509; GO:0030514; GO:0031012; GO:0032880; GO:0042118; GO:0045765; GO:0048839; GO:0060393; GO:0062023; GO:0070374; GO:1903672 37873 FUN_016988 1777 1359 1295 1777 1023 ptg000011l:9925296-9943521 Q8CJ69 4.03e-23 BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2) Mus musculus (Mouse) blood vessel development [GO:0001568]; blood vessel endothelial cell proliferation involved in sprouting angiogenesis [GO:0002043]; BMP signaling pathway [GO:0030509]; common-partner SMAD protein phosphorylation [GO:0007182]; endothelial cell activation [GO:0042118]; inner ear development [GO:0048839]; negative regulation of BMP signaling pathway [GO:0030514]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of sprouting angiogenesis [GO:1903672]; regulation of angiogenesis [GO:0045765]; regulation of endothelial cell migration [GO:0010594]; regulation of pathway-restricted SMAD protein phosphorylation [GO:0060393]; regulation of protein localization [GO:0032880]; ureteric bud development [GO:0001657] GO:0001568; GO:0001657; GO:0002043; GO:0005576; GO:0005615; GO:0007182; GO:0010594; GO:0030509; GO:0030514; GO:0031012; GO:0032880; GO:0042118; GO:0045765; GO:0048839; GO:0060393; GO:0062023; GO:0070374; GO:1903672 37874 FUN_016989 164 66 35 52 107 NA NA NA NA NA NA NA 37875 FUN_029171 5998 3896 2096 4384 3255 NA NA NA NA NA NA NA 37876 FUN_044172 1 0 8 6 19 NA NA NA NA NA NA NA 37877 FUN_029173 35474 50618 23069 33855 23387 NA NA NA NA NA NA NA 37878 FUN_029172 9879 26563 9499 18398 8641 NA NA NA NA NA NA NA 37879 FUN_016983 1069 1011 342 1015 898 ptg000011l:9784609-9795699 Q9P203 1.54e-56 BTB/POZ domain-containing protein 7 Homo sapiens (Human) morphogenesis of a branching epithelium [GO:0061138]; regulation of branching involved in salivary gland morphogenesis [GO:0060693] GO:0005634; GO:0060693; GO:0061138 37880 FUN_016980 11 0 4 19 0 NA NA NA NA NA NA NA 37881 FUN_014213 5 15 0 20 0 NA NA NA NA NA NA NA 37882 FUN_029179 415 186 259 224 603 ptg000022l:9034410-9039697 Q9SP32 1.23e-24 Endoribonuclease Dicer homolog 1 (EC 3.1.26.-) (Dicer-like protein 1) (AtDCL1) (Protein ABNORMAL SUSPENSOR 1) (Protein CARPEL FACTORY) (Protein SHORT INTEGUMENTS 1) (Protein SUSPENSOR 1) Arabidopsis thaliana (Mouse-ear cress) rRNA processing [GO:0006364]; siRNA processing [GO:0030422] GO:0003676; GO:0003677; GO:0003723; GO:0004386; GO:0004525; GO:0005524; GO:0005634; GO:0005737; GO:0006364; GO:0030422; GO:0046872 37883 FUN_016987 46417 90002 17431 48653 18687 NA NA NA NA NA NA NA 37884 FUN_016984 701 792 770 1766 1064 NA NA NA NA NA NA NA 37885 FUN_033723 220 381 203 286 753 ptg000024l:693247-699385 Q3URF8 7.81e-21 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 37886 FUN_033722 1442 833 1036 1120 1136 ptg000024l:686513-688990 Q3URF8 2.08e-21 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 37887 FUN_033721 2254 1141 1142 1596 587 NA NA NA NA NA NA NA 37888 FUN_033720 509 826 572 610 521 ptg000024l:673513-676224 Q8VDL4 3.81e-36 ADP-dependent glucokinase (ADP-GK) (ADPGK) (EC 2.7.1.147) Mus musculus (Mouse) carbohydrate metabolic process [GO:0005975]; glucose metabolic process [GO:0006006]; glycolytic process [GO:0006096] GO:0005576; GO:0005783; GO:0005975; GO:0006006; GO:0006096; GO:0043843; GO:0046872 37889 FUN_033727 105 3441 873 64 3 ptg000024l:724957-726965 Q3URF8 6.72e-23 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 37890 FUN_033726 14 1122 91 0 0 ptg000024l:709408-715539 Q3URF8 7.68e-22 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 37891 FUN_033725 1119 2051 697 581 10 ptg000024l:703417-706602 Q3URF8 1.66e-22 BTB/POZ domain-containing protein KCTD21 (KCASH2 protein) (Potassium channel tetramerization domain-containing protein 21) Mus musculus (Mouse) negative regulation of smoothened signaling pathway [GO:0045879]; protein homooligomerization [GO:0051260]; protein ubiquitination [GO:0016567]; ubiquitin-dependent protein catabolic process [GO:0006511] GO:0006511; GO:0016567; GO:0042802; GO:0042826; GO:0045879; GO:0051260; GO:0097602 37892 FUN_033724 379 672 370 385 20 NA NA NA NA NA NA NA 37893 FUN_028886 1126 931 1043 1224 1220 NA NA NA NA NA NA NA 37894 FUN_028887 183 90 184 191 170 ptg000022l:5609170-5615710 Q9NQX0 5.6e-21 Putative histone-lysine N-methyltransferase PRDM6 (EC 2.1.1.361) (PR domain zinc finger protein 6) (PR domain-containing protein 6) Homo sapiens (Human) chromatin organization [GO:0006325]; histone methylation [GO:0016571]; negative regulation of smooth muscle cell differentiation [GO:0051151]; negative regulation of transcription by RNA polymerase II [GO:0000122]; neurogenesis [GO:0022008]; regulation of gene expression [GO:0010468] GO:0000122; GO:0005634; GO:0006325; GO:0010468; GO:0016571; GO:0022008; GO:0042802; GO:0046872; GO:0051151; GO:0140944 37895 FUN_033729 946 601 573 1208 1584 NA NA NA NA NA NA NA 37896 FUN_033728 2 460 103 6 0 NA NA NA NA NA NA NA 37897 FUN_028883 61 0 13 38 27 NA NA NA NA NA NA NA 37898 FUN_028880 28 0 16 6 20 NA NA NA NA NA NA NA 37899 FUN_040382 0 0 0 0 106 NA NA NA NA NA NA NA 37900 FUN_040381 0 0 20 25 75 ptg000031l:7663543-7671669 P51228 3.42e-28 Protein CfxQ homolog Porphyra purpurea (Red seaweed) (Ulva purpurea) NA GO:0005524; GO:0009507; GO:0016887 37901 FUN_040387 0 0 8 0 0 NA NA NA NA NA NA NA 37902 FUN_004699 543 349 262 437 160 NA NA NA NA NA NA NA 37903 FUN_040389 52 0 0 4 0 NA NA NA NA NA NA NA 37904 FUN_004698 747 1176 650 1238 621 NA NA NA NA NA NA NA 37905 FUN_043179 886 272 505 1490 2066 ptg000047l:5069758-5101008 Q96RW7 6.06e-22 Hemicentin-1 (Fibulin-6) (FIBL-6) Homo sapiens (Human) actin filament reorganization [GO:0090527]; basement membrane organization [GO:0071711]; cell cycle [GO:0007049]; cell division [GO:0051301]; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [GO:0007157]; homophilic cell adhesion via plasma membrane adhesion molecules [GO:0007156]; response to bacterium [GO:0009617]; visual perception [GO:0007601] GO:0005201; GO:0005509; GO:0005604; GO:0005737; GO:0005912; GO:0005927; GO:0005938; GO:0007049; GO:0007156; GO:0007157; GO:0007601; GO:0009617; GO:0032154; GO:0051301; GO:0062023; GO:0070062; GO:0071711; GO:0090527 37906 FUN_004695 3599 2545 1865 3176 3053 NA NA NA NA NA NA NA 37907 FUN_020996 0 0 0 0 61 NA NA NA NA NA NA NA 37908 FUN_004694 1253 829 987 1416 1716 ntLink_8:25878833-25889597 Q9UBS9 4.3e-50 SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia homolog) (SUN-like protein 1) Homo sapiens (Human) ossification [GO:0001503]; positive regulation of collagen biosynthetic process [GO:0032967]; positive regulation of osteoblast differentiation [GO:0045669]; regulation of bone remodeling [GO:0046850] GO:0001503; GO:0005737; GO:0005791; GO:0016020; GO:0030867; GO:0032967; GO:0045669; GO:0046850 37909 FUN_020997 15 2 73 0 263 NA NA NA NA NA NA NA 37910 FUN_015989 461 294 317 400 291 NA NA NA NA NA NA NA 37911 FUN_028229 2922 2255 1199 2354 1801 ptg000021l:17104680-17125617 P14381 1.45e-106 Transposon TX1 uncharacterized 149 kDa protein (ORF 2) Xenopus laevis (African clawed frog) NA GO:0003824 37912 FUN_043178 183 152 82 166 149 ptg000047l:5061370-5066580 Q8NHH1 3.87e-82 Tubulin polyglutamylase TTLL11 (EC 6.3.2.-) (Tubulin--tyrosine ligase-like protein 11) Homo sapiens (Human) microtubule cytoskeleton organization [GO:0000226]; microtubule severing [GO:0051013]; protein polyglutamylation [GO:0018095] GO:0000226; GO:0005524; GO:0005829; GO:0005874; GO:0005929; GO:0015631; GO:0018095; GO:0036064; GO:0046872; GO:0051013; GO:0070740 37913 FUN_015983 383 235 196 231 383 ptg000010l:154791-160957 Q99575 5.41e-43 Ribonucleases P/MRP protein subunit POP1 (hPOP1) Homo sapiens (Human) RNA phosphodiester bond hydrolysis, endonucleolytic [GO:0090502]; tRNA 5'-leader removal [GO:0001682]; tRNA catabolic process [GO:0016078]; tRNA processing [GO:0008033] GO:0000172; GO:0001682; GO:0003723; GO:0004526; GO:0005615; GO:0005654; GO:0005655; GO:0005730; GO:0008033; GO:0016078; GO:0030681; GO:0033204; GO:0090502 37914 FUN_015982 410 190 509 887 402 ptg000010l:113981-154237 Q61001 1.03e-23 Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha) Mus musculus (Mouse) animal organ morphogenesis [GO:0009887]; axon guidance [GO:0007411]; branching involved in salivary gland morphogenesis [GO:0060445]; branching involved in ureteric bud morphogenesis [GO:0001658]; branching morphogenesis of an epithelial tube [GO:0048754]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; cilium assembly [GO:0060271]; hair follicle development [GO:0001942]; integrin-mediated signaling pathway [GO:0007229]; kidney development [GO:0001822]; lung development [GO:0030324]; morphogenesis of a polarized epithelium [GO:0001738]; morphogenesis of embryonic epithelium [GO:0016331]; muscle organ development [GO:0007517]; neural crest cell migration [GO:0001755]; odontogenesis of dentin-containing tooth [GO:0042475]; postsynapse organization [GO:0099173]; protein localization to plasma membrane [GO:0072659]; regulation of cell adhesion [GO:0030155]; regulation of cell migration [GO:0030334]; regulation of embryonic development [GO:0045995]; regulation of epithelial cell proliferation [GO:0050678]; substrate adhesion-dependent cell spreading [GO:0034446]; tissue development [GO:0009888]; trunk neural crest cell migration [GO:0036484] GO:0001658; GO:0001738; GO:0001755; GO:0001822; GO:0001942; GO:0005178; GO:0005201; GO:0005576; GO:0005604; GO:0005610; GO:0005615; GO:0007229; GO:0007411; GO:0007517; GO:0009887; GO:0009888; GO:0016331; GO:0016477; GO:0030155; GO:0030324; GO:0030334; GO:0031012; GO:0031594; GO:0034446; GO:0036484; GO:0042475; GO:0043083; GO:0043259; GO:0045995; GO:0048754; GO:0050678; GO:0060271; GO:0060445; GO:0062023; GO:0072659; GO:0098609; GO:0098965; GO:0098978; GO:0099173 37915 FUN_028220 0 229 0 112 275 NA NA NA NA NA NA NA 37916 FUN_028226 313 337 210 260 374 NA NA NA NA NA NA NA 37917 FUN_015986 115 79 48 131 46 NA NA NA NA NA NA NA 37918 FUN_015985 863 359 359 740 582 NA NA NA NA NA NA NA 37919 FUN_028225 419 1037 94 241 35 NA NA NA NA NA NA NA 37920 FUN_010755 3184 1875 2106 2501 1582 NA NA NA NA NA NA NA 37921 FUN_010754 521 760 126 377 430 NA NA NA NA NA NA NA 37922 FUN_010757 158 184 41 79 118 NA NA NA NA NA NA NA 37923 FUN_010756 551 384 130 594 546 NA NA NA NA NA NA NA 37924 FUN_010751 379 223 0 376 442 NA NA NA NA NA NA NA 37925 FUN_010750 1542 541 543 1010 942 NA NA NA NA NA NA NA 37926 FUN_010753 1014 950 726 585 438 NA NA NA NA NA NA NA 37927 FUN_010752 446 153 53 252 123 NA NA NA NA NA NA NA 37928 FUN_012794 404 419 184 872 709 ptg000008l:12899908-12908434 F1M3J4 1.26e-92 ATP-binding cassette subfamily C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Rattus norvegicus (Rat) bile acid and bile salt transport [GO:0015721]; bile acid signaling pathway [GO:0038183]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410]; transmembrane transport [GO:0055085]; urate transport [GO:0015747] GO:0001409; GO:0005524; GO:0005886; GO:0008559; GO:0009410; GO:0010033; GO:0010243; GO:0014070; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0038183; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115 37929 FUN_012794 404 419 184 872 709 ptg000008l:12899908-12908434 F1M3J4 6.2e-65 ATP-binding cassette subfamily C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 4) Rattus norvegicus (Rat) bile acid and bile salt transport [GO:0015721]; bile acid signaling pathway [GO:0038183]; cAMP transport [GO:0070730]; cilium assembly [GO:0060271]; export across plasma membrane [GO:0140115]; leukotriene transport [GO:0071716]; positive regulation of smooth muscle cell proliferation [GO:0048661]; prostaglandin secretion [GO:0032310]; prostaglandin transport [GO:0015732]; response to organic cyclic compound [GO:0014070]; response to organic substance [GO:0010033]; response to organonitrogen compound [GO:0010243]; response to xenobiotic stimulus [GO:0009410]; transmembrane transport [GO:0055085]; urate transport [GO:0015747] GO:0001409; GO:0005524; GO:0005886; GO:0008559; GO:0009410; GO:0010033; GO:0010243; GO:0014070; GO:0015132; GO:0015143; GO:0015216; GO:0015431; GO:0015432; GO:0015562; GO:0015721; GO:0015732; GO:0015747; GO:0016020; GO:0016323; GO:0016324; GO:0016887; GO:0031088; GO:0032310; GO:0034634; GO:0038183; GO:0042626; GO:0042910; GO:0048661; GO:0055085; GO:0060271; GO:0070730; GO:0071716; GO:0098591; GO:0140115 37930 FUN_010759 241 100 0 124 78 NA NA NA NA NA NA NA 37931 FUN_022882 4 0 31 0 63 NA NA NA NA NA NA NA 37932 FUN_022883 1437 1242 898 1661 1099 ptg000017l:1023723-1044296 P48442 6.84e-121 Extracellular calcium-sensing receptor (CaSR) (Parathyroid cell calcium-sensing receptor) (PCaR1) (RaKCaR) Rattus norvegicus (Rat) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; apoptotic process [GO:0006915]; bile acid secretion [GO:0032782]; branching morphogenesis of an epithelial tube [GO:0048754]; calcium ion import [GO:0070509]; cellular calcium ion homeostasis [GO:0006874]; cellular response to glucose stimulus [GO:0071333]; cellular response to hepatocyte growth factor stimulus [GO:0035729]; cellular response to hypoxia [GO:0071456]; cellular response to low-density lipoprotein particle stimulus [GO:0071404]; cellular response to peptide [GO:1901653]; cellular response to vitamin D [GO:0071305]; chloride transmembrane transport [GO:1902476]; detection of calcium ion [GO:0005513]; fat pad development [GO:0060613]; G protein-coupled receptor signaling pathway [GO:0007186]; JNK cascade [GO:0007254]; ossification [GO:0001503]; phospholipase C-activating G protein-coupled receptor signaling pathway [GO:0007200]; positive regulation of ATP-dependent activity [GO:0032781]; positive regulation of calcium ion import [GO:0090280]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of gene expression [GO:0010628]; positive regulation of insulin secretion [GO:0032024]; positive regulation of positive chemotaxis [GO:0050927]; positive regulation of vasoconstriction [GO:0045907]; regulation of calcium ion transport [GO:0051924]; response to calcium ion [GO:0051592]; response to fibroblast growth factor [GO:0071774]; response to ischemia [GO:0002931]; response to metal ion [GO:0010038]; response to organic cyclic compound [GO:0014070]; vasodilation [GO:0042311] GO:0001503; GO:0002931; GO:0004930; GO:0005178; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0006874; GO:0006915; GO:0007186; GO:0007193; GO:0007200; GO:0007254; GO:0008284; GO:0009986; GO:0010038; GO:0010628; GO:0014070; GO:0016020; GO:0016323; GO:0016324; GO:0016597; GO:0019901; GO:0030424; GO:0032024; GO:0032781; GO:0032782; GO:0035729; GO:0042311; GO:0042803; GO:0043005; GO:0043025; GO:0043679; GO:0044325; GO:0045907; GO:0048754; GO:0050927; GO:0051592; GO:0051924; GO:0060613; GO:0070374; GO:0070509; GO:0071305; GO:0071333; GO:0071404; GO:0071456; GO:0071774; GO:0090280; GO:1901653; GO:1902476 37933 FUN_017298 0 8 0 0 0 NA NA NA NA NA NA NA 37934 FUN_012669 133 32 146 230 49 NA NA NA NA NA NA NA 37935 FUN_012668 4327 2677 1700 4437 3250 NA NA NA NA NA NA NA 37936 FUN_012667 1 11 0 1 2 NA NA NA NA NA NA NA 37937 FUN_012666 436 1764 1247 901 1067 ptg000008l:11093345-11126309 Q9CUX1 1.28e-30 52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12) Mus musculus (Mouse) NA GO:0003677; GO:0005634; GO:0046872; GO:0046983 37938 FUN_017297 0 51 2 0 1 NA NA NA NA NA NA NA 37939 FUN_012664 2041 890 1442 2991 1340 NA NA NA NA NA NA NA 37940 FUN_017291 0 0 50 0 9 NA NA NA NA NA NA NA 37941 FUN_012660 2141 2290 1123 1610 957 NA NA NA NA NA NA NA 37942 FUN_009400 0 0 0 0 27 ptg000004l:6409645-6410478 B8VIU6 1.87e-33 Uncharacterized skeletal organic matrix protein 5 (Uncharacterized SOMP-5) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0005576 37943 FUN_038934 6289 5434 3913 6448 4507 ptg000027l:13017531-13027219 Q5BP74 1.58e-39 Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0016055; GO:0106310 37944 FUN_038934 6289 5434 3913 6448 4507 ptg000027l:13017531-13027219 Q5BP74 7.74e-27 Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0016055; GO:0106310 37945 FUN_038934 6289 5434 3913 6448 4507 ptg000027l:13017531-13027219 Q5BP74 3.07e-22 Casein kinase I isoform delta (CKI-delta) (CKId) (EC 2.7.11.1) (Tau-protein kinase CSNK1D) (EC 2.7.11.26) Xenopus laevis (African clawed frog) protein phosphorylation [GO:0006468]; Wnt signaling pathway [GO:0016055] GO:0004672; GO:0004674; GO:0005524; GO:0005634; GO:0005737; GO:0006468; GO:0016055; GO:0106310 37946 FUN_038933 2956 2330 1305 3095 2070 ptg000027l:13005604-13015339 Q9UPR5 7.77e-47 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; ion transport [GO:0006811]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808]; transport across blood-brain barrier [GO:0150104] GO:0002931; GO:0005432; GO:0005516; GO:0005886; GO:0006811; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0043025; GO:0043197; GO:0043204; GO:0043679; GO:0045202; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:0150104; GO:1903779; GO:1905060; GO:1990034 37947 FUN_038933 2956 2330 1305 3095 2070 ptg000027l:13005604-13015339 Q9UPR5 5.56e-21 Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) Homo sapiens (Human) calcium ion export across plasma membrane [GO:1990034]; calcium ion import across plasma membrane [GO:0098703]; calcium ion transmembrane transport [GO:0070588]; cell communication [GO:0007154]; cellular calcium ion homeostasis [GO:0006874]; cognition [GO:0050890]; ion transport [GO:0006811]; learning [GO:0007612]; learning or memory [GO:0007611]; long-term synaptic potentiation [GO:0060291]; memory [GO:0007613]; metal ion transport [GO:0030001]; modulation of excitatory postsynaptic potential [GO:0098815]; neuron cellular homeostasis [GO:0070050]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; regulation of action potential firing pattern [GO:0099608]; regulation of calcineurin-mediated signaling [GO:0106056]; regulation of cardiac conduction [GO:1903779]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of gene expression [GO:0010468]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; response to ischemia [GO:0002931]; sodium ion transmembrane transport [GO:0035725]; synapse organization [GO:0050808]; transport across blood-brain barrier [GO:0150104] GO:0002931; GO:0005432; GO:0005516; GO:0005886; GO:0006811; GO:0006874; GO:0007154; GO:0007611; GO:0007612; GO:0007613; GO:0010468; GO:0014069; GO:0015081; GO:0015085; GO:0016020; GO:0016323; GO:0030001; GO:0030424; GO:0030425; GO:0035725; GO:0042383; GO:0043025; GO:0043197; GO:0043204; GO:0043679; GO:0045202; GO:0046872; GO:0048172; GO:0050808; GO:0050890; GO:0051480; GO:0060291; GO:0070050; GO:0070588; GO:0071902; GO:0098703; GO:0098793; GO:0098794; GO:0098815; GO:0099608; GO:0106056; GO:0150104; GO:1903779; GO:1905060; GO:1990034 37948 FUN_038932 46 0 23 11 25 NA NA NA NA NA NA NA 37949 FUN_038930 49 35 1 64 254 ptg000027l:12972442-12973459 C3ZQF9 1.04e-26 QRFP-like peptide receptor Branchiostoma floridae (Florida lancelet) (Amphioxus) cellular response to peptide [GO:1901653]; G protein-coupled receptor signaling pathway [GO:0007186] GO:0004930; GO:0004983; GO:0005886; GO:0007186; GO:1901653 37950 FUN_038939 178 60 61 119 122 NA NA NA NA NA NA NA 37951 FUN_011408 63 3 57 14 235 NA NA NA NA NA NA NA 37952 FUN_043129 775 1250 789 629 731 NA NA NA NA NA NA NA 37953 FUN_043122 719 308 463 83 386 ptg000047l:4357401-4364653 Q9ULJ7 1.12e-45 Ankyrin repeat domain-containing protein 50 Homo sapiens (Human) endocytic recycling [GO:0032456]; protein transport [GO:0015031] GO:0005768; GO:0015031; GO:0032456 37954 FUN_043123 57 20 119 5 38 NA NA NA NA NA NA NA 37955 FUN_043120 95 26 62 49 93 NA NA NA NA NA NA NA 37956 FUN_043126 208 40 218 205 150 ptg000047l:4394782-4396456 Q1LZE9 2.12e-30 Serine protease 23 (EC 3.4.21.-) Bos taurus (Bovine) proteolysis [GO:0006508] GO:0004252; GO:0005576; GO:0005634; GO:0006508 37957 FUN_011407 2 0 0 0 8 NA NA NA NA NA NA NA 37958 FUN_011404 25 0 20 7 72 NA NA NA NA NA NA NA 37959 FUN_011405 359 3 67 12 442 NA NA NA NA NA NA NA 37960 FUN_013138 1388 834 1094 4043 562 NA NA NA NA NA NA NA 37961 FUN_013139 1156 743 754 774 613 NA NA NA NA NA NA NA 37962 FUN_013135 866 689 746 1257 765 NA NA NA NA NA NA NA 37963 FUN_013136 0 0 0 47 7 NA NA NA NA NA NA NA 37964 FUN_013137 121 200 122 527 185 ptg000008l:19960352-19973748 P0CT39 3.09e-66 Transposon Tf2-6 polyprotein (Retrotransposable element Tf2 155 kDa protein) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) DNA integration [GO:0015074]; DNA recombination [GO:0006310]; proteolysis [GO:0006508] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004519; GO:0005634; GO:0006310; GO:0006508; GO:0015074; GO:0046872 37965 FUN_013130 25 0 16 0 6 NA NA NA NA NA NA NA 37966 FUN_013131 0 0 2 0 22 NA NA NA NA NA NA NA 37967 FUN_013132 81 133 72 115 138 NA NA NA NA NA NA NA 37968 FUN_013133 26 31 28 73 45 ptg000008l:19895363-19904531 P22757 1.74e-25 Hatching enzyme (HE) (HEZ) (EC 3.4.24.12) (Envelysin) (Sea-urchin-hatching proteinase) [Cleaved into: Hatching enzyme 18 kDa form] Paracentrotus lividus (Common sea urchin) proteolysis [GO:0006508] GO:0004222; GO:0006508; GO:0008270; GO:0031012 37969 FUN_035084 9 10 49 42 24 ptg000025l:3590853-3593375 E7FAM5 1.17e-92 E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71) Danio rerio (Zebrafish) (Brachydanio rerio) embryonic body morphogenesis [GO:0010172]; fibroblast growth factor receptor signaling pathway [GO:0008543]; G1/S transition of mitotic cell cycle [GO:0000082]; miRNA metabolic process [GO:0010586]; miRNA-mediated gene silencing by inhibition of translation [GO:0035278]; negative regulation of translation [GO:0017148]; neural tube development [GO:0021915]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein autoubiquitination [GO:0051865]; protein polyubiquitination [GO:0000209]; regulation of miRNA-mediated gene silencing [GO:0060964]; regulation of neural precursor cell proliferation [GO:2000177]; stem cell proliferation [GO:0072089] GO:0000082; GO:0000209; GO:0000932; GO:0004842; GO:0008270; GO:0008543; GO:0010172; GO:0010586; GO:0017148; GO:0021915; GO:0030371; GO:0035198; GO:0035278; GO:0043161; GO:0051865; GO:0060964; GO:0061630; GO:0072089; GO:2000177 37970 FUN_023420 1118 612 428 1087 927 NA NA NA NA NA NA NA 37971 FUN_023423 5594 3066 2559 4450 3354 ptg000017l:7350950-7371559 Q61301 9.5e-46 Catenin alpha-2 (Alpha N-catenin) Mus musculus (Mouse) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of synapse structural plasticity [GO:0051823] GO:0005198; GO:0005634; GO:0005737; GO:0005912; GO:0007409; GO:0008013; GO:0010975; GO:0014069; GO:0015629; GO:0016323; GO:0016342; GO:0016477; GO:0021942; GO:0030027; GO:0030424; GO:0034316; GO:0042802; GO:0045296; GO:0048813; GO:0048854; GO:0051015; GO:0051823; GO:0060134; GO:0098609; GO:0098686; GO:0098688; GO:0098831; GO:0098885; GO:0098888; GO:0098890; GO:0099092; GO:2001222 37972 FUN_023423 5594 3066 2559 4450 3354 ptg000017l:7350950-7371559 Q61301 9.5e-46 Catenin alpha-2 (Alpha N-catenin) Mus musculus (Mouse) axonogenesis [GO:0007409]; brain morphogenesis [GO:0048854]; cell migration [GO:0016477]; cell-cell adhesion [GO:0098609]; dendrite morphogenesis [GO:0048813]; modification of postsynaptic actin cytoskeleton [GO:0098885]; negative regulation of Arp2/3 complex-mediated actin nucleation [GO:0034316]; prepulse inhibition [GO:0060134]; radial glia guided migration of Purkinje cell [GO:0021942]; regulation of neuron migration [GO:2001222]; regulation of neuron projection development [GO:0010975]; regulation of synapse structural plasticity [GO:0051823] GO:0005198; GO:0005634; GO:0005737; GO:0005912; GO:0007409; GO:0008013; GO:0010975; GO:0014069; GO:0015629; GO:0016323; GO:0016342; GO:0016477; GO:0021942; GO:0030027; GO:0030424; GO:0034316; GO:0042802; GO:0045296; GO:0048813; GO:0048854; GO:0051015; GO:0051823; GO:0060134; GO:0098609; GO:0098686; GO:0098688; GO:0098831; GO:0098885; GO:0098888; GO:0098890; GO:0099092; GO:2001222 37973 FUN_023422 1405 1341 1035 1504 2212 NA NA NA NA NA NA NA 37974 FUN_023425 0 0 0 0 34 NA NA NA NA NA NA NA 37975 FUN_026412 2061 3334 1868 2530 1927 NA NA NA NA NA NA NA 37976 FUN_026410 3160 7039 1349 2498 2058 NA NA NA NA NA NA NA 37977 FUN_023357 396 369 54 548 201 NA NA NA NA NA NA NA 37978 FUN_009269 213 214 75 73 70 NA NA NA NA NA NA NA 37979 FUN_009268 128 57 30 99 141 NA NA NA NA NA NA NA 37980 FUN_009267 2330 1159 879 1826 1063 NA NA NA NA NA NA NA 37981 FUN_009266 2028 1232 1216 2396 1737 NA NA NA NA NA NA NA 37982 FUN_009265 0 0 0 0 17 NA NA NA NA NA NA NA 37983 FUN_009264 0 11 0 3 0 NA NA NA NA NA NA NA 37984 FUN_009262 87 66 31 27 110 ptg000004l:4646163-4652166 Q96AY4 8.45e-165 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37985 FUN_009262 87 66 31 27 110 ptg000004l:4646163-4652166 Q96AY4 1.59e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37986 FUN_009262 87 66 31 27 110 ptg000004l:4646163-4652166 Q96AY4 5.58e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37987 FUN_009262 87 66 31 27 110 ptg000004l:4646163-4652166 Q96AY4 1.07e-150 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37988 FUN_009262 87 66 31 27 110 ptg000004l:4646163-4652166 Q96AY4 1.34e-27 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37989 FUN_009261 0 0 0 0 13 NA NA NA NA NA NA NA 37990 FUN_035089 101 109 45 21 17 ptg000025l:3654851-3662760 Q9UHC6 1.5e-69 Contactin-associated protein-like 2 (Cell recognition molecule Caspr2) Homo sapiens (Human) adult behavior [GO:0030534]; brain development [GO:0007420]; cell adhesion [GO:0007155]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; clustering of voltage-gated potassium channels [GO:0045163]; learning [GO:0007612]; limbic system development [GO:0021761]; neuron projection development [GO:0031175]; neuron projection morphogenesis [GO:0048812]; neuron recognition [GO:0008038]; positive regulation of gap junction assembly [GO:1903598]; protein localization to juxtaparanode region of axon [GO:0071205]; social behavior [GO:0035176]; striatum development [GO:0021756]; superior temporal gyrus development [GO:0071109]; thalamus development [GO:0021794]; transmission of nerve impulse [GO:0019226]; vocal learning [GO:0042297]; vocalization behavior [GO:0071625] GO:0005769; GO:0005794; GO:0007155; GO:0007420; GO:0007612; GO:0008038; GO:0008076; GO:0008283; GO:0009986; GO:0016020; GO:0019226; GO:0019899; GO:0021756; GO:0021761; GO:0021794; GO:0021987; GO:0030424; GO:0030425; GO:0030534; GO:0030673; GO:0031175; GO:0033010; GO:0035176; GO:0042297; GO:0043025; GO:0043204; GO:0044224; GO:0045163; GO:0048812; GO:0071109; GO:0071205; GO:0071625; GO:1903598 37991 FUN_026679 2499 591 1629 1838 1474 ptg000020l:12371702-12382262 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37992 FUN_026679 2499 591 1629 1838 1474 ptg000020l:12371702-12382262 Q9NZJ4 1.48e-52 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37993 FUN_026679 2499 591 1629 1838 1474 ptg000020l:12371702-12382262 Q9NZJ4 2.6e-42 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37994 FUN_026679 2499 591 1629 1838 1474 ptg000020l:12371702-12382262 Q9NZJ4 7.7e-32 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 37995 FUN_026677 0 13 0 0 0 NA NA NA NA NA NA NA 37996 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 1.86e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37997 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 9.06e-168 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37998 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 8.36e-167 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 37999 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 2.71e-156 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38000 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 2.72e-155 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38001 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 8.92e-137 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38002 FUN_026676 88 78 0 59 67 ptg000020l:12338442-12346281 Q96AY4 2.32e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38003 FUN_026675 124 642 1194 2298 3257 ptg000020l:12292311-12304164 Q9NZJ4 0 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 38004 FUN_026675 124 642 1194 2298 3257 ptg000020l:12292311-12304164 Q9NZJ4 3.9e-54 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 38005 FUN_026675 124 642 1194 2298 3257 ptg000020l:12292311-12304164 Q9NZJ4 9.66e-43 Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) Homo sapiens (Human) negative regulation of inclusion body assembly [GO:0090084]; protein folding [GO:0006457] GO:0005634; GO:0005737; GO:0005739; GO:0006457; GO:0030424; GO:0030425; GO:0030544; GO:0042802; GO:0051087; GO:0070628; GO:0070852; GO:0090084 38006 FUN_039959 443 253 346 427 453 ptg000031l:2123686-2127178 Q96AY4 9.9e-44 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38007 FUN_039959 443 253 346 427 453 ptg000031l:2123686-2127178 Q96AY4 2.3e-41 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38008 FUN_039959 443 253 346 427 453 ptg000031l:2123686-2127178 Q96AY4 8.47e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38009 FUN_039959 443 253 346 427 453 ptg000031l:2123686-2127178 Q96AY4 3.28e-39 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38010 FUN_039959 443 253 346 427 453 ptg000031l:2123686-2127178 Q96AY4 1.47e-32 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38011 FUN_026673 666 539 10 0 0 NA NA NA NA NA NA NA 38012 FUN_026672 21032 23621 12277 18835 9684 NA NA NA NA NA NA NA 38013 FUN_026670 16 0 0 0 0 NA NA NA NA NA NA NA 38014 FUN_015473 920 1037 808 745 513 ptg000009l:10614608-10615495 Q4QR62 2.38e-24 Mitochondrial import inner membrane translocase subunit Tim10-A Xenopus laevis (African clawed frog) protein transport [GO:0015031] GO:0005743; GO:0015031; GO:0046872 38015 FUN_015472 669 1427 618 1257 1053 NA NA NA NA NA NA NA 38016 FUN_015471 560 354 478 373 489 NA NA NA NA NA NA NA 38017 FUN_015470 2666 1045 1661 2847 2274 NA NA NA NA NA NA NA 38018 FUN_015476 64 0 10 13 0 NA NA NA NA NA NA NA 38019 FUN_015475 227 16 20 128 28 ptg000009l:10651152-10656394 Q9CPR1 1.99e-30 RWD domain-containing protein 4 Mus musculus (Mouse) NA NA 38020 FUN_015474 1242 578 606 1059 696 NA NA NA NA NA NA NA 38021 FUN_015478 891 601 149 741 351 NA NA NA NA NA NA NA 38022 FUN_025098 11426 7540 5482 8944 7242 ptg000018l:13795330-13800447 P31403 3.57e-23 V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0033179; GO:0046961 38023 FUN_025098 11426 7540 5482 8944 7242 ptg000018l:13795330-13800447 P31403 3.57e-23 V-type proton ATPase 16 kDa proteolipid subunit c (V-ATPase 16 kDa proteolipid subunit c) (Vacuolar proton pump 16 kDa proteolipid subunit c) Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) NA GO:0033179; GO:0046961 38024 FUN_025099 0 0 0 4 28 ptg000018l:13804281-13810053 P21329 2.48e-26 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila funebris (Fruit fly) NA GO:0003964 38025 FUN_025099 0 0 0 4 28 ptg000018l:13804281-13810053 P21329 2.48e-26 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila funebris (Fruit fly) NA GO:0003964 38026 FUN_025099 0 0 0 4 28 ptg000018l:13804281-13810053 P21329 2.48e-26 RNA-directed DNA polymerase from mobile element jockey (EC 2.7.7.49) (Reverse transcriptase) Drosophila funebris (Fruit fly) NA GO:0003964 38027 FUN_025092 22 22 8 24 53 NA NA NA NA NA NA NA 38028 FUN_025090 0 0 0 0 15 NA NA NA NA NA NA NA 38029 FUN_025096 0 12 0 0 8 NA NA NA NA NA NA NA 38030 FUN_025097 2297 1925 1766 2739 2188 ptg000018l:13752081-13784166 Q95SX7 1.12e-34 Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) Drosophila melanogaster (Fruit fly) transposition, DNA-mediated [GO:0006313] GO:0003964; GO:0006313 38031 FUN_025095 0 0 0 8 14 NA NA NA NA NA NA NA 38032 FUN_017938 589 366 404 580 709 ptg000012l:2129929-2134271 Q13613 6.83e-36 Myotubularin-related protein 1 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) Homo sapiens (Human) phosphatidylinositol biosynthetic process [GO:0006661]; phosphatidylinositol dephosphorylation [GO:0046856]; regulation of phosphatidylinositol dephosphorylation [GO:0060304] GO:0004438; GO:0005737; GO:0005829; GO:0005886; GO:0006661; GO:0042803; GO:0046856; GO:0052629; GO:0060304 38033 FUN_017939 395 278 207 408 282 NA NA NA NA NA NA NA 38034 FUN_018748 210 132 132 51 52 NA NA NA NA NA NA NA 38035 FUN_017930 1199 849 775 1317 1135 ptg000012l:2062941-2069808 O75165 8.44e-24 DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8) Homo sapiens (Human) endosome organization [GO:0007032]; osteoblast differentiation [GO:0001649]; protein transport [GO:0015031]; receptor-mediated endocytosis [GO:0006898]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of early endosome to recycling endosome transport [GO:1902954] GO:0001649; GO:0005765; GO:0005829; GO:0005886; GO:0006898; GO:0007032; GO:0010008; GO:0015031; GO:0016020; GO:0030667; GO:0031901; GO:0035577; GO:0043231; GO:0070062; GO:1902954; GO:2000641 38036 FUN_018747 2 13 0 4 0 NA NA NA NA NA NA NA 38037 FUN_017616 17 85 13 8 36 NA NA NA NA NA NA NA 38038 FUN_017934 22 23 0 25 4 NA NA NA NA NA NA NA 38039 FUN_017935 1660 1274 549 741 331 NA NA NA NA NA NA NA 38040 FUN_018740 143 0 0 0 0 NA NA NA NA NA NA NA 38041 FUN_017937 5048 3169 2572 2462 2195 NA NA NA NA NA NA NA 38042 FUN_023352 1542 1985 881 1553 646 NA NA NA NA NA NA NA 38043 FUN_025328 62 21 59 42 129 NA NA NA NA NA NA NA 38044 FUN_025324 2033 1310 928 1667 807 ptg000019l:1263618-1285035 Q9Y6Y1 1.78e-57 Calmodulin-binding transcription activator 1 Homo sapiens (Human) neuromuscular process controlling balance [GO:0050885]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of protein dephosphorylation [GO:0035307]; positive regulation of transcription by RNA polymerase II [GO:0045944]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0003690; GO:0003712; GO:0005634; GO:0005730; GO:0005829; GO:0006357; GO:0035307; GO:0043565; GO:0045944; GO:0050885; GO:0070886 38045 FUN_025325 2511 1169 1186 1375 1763 ptg000019l:1301940-1302981 Q18694 1.47e-21 Forkhead box protein unc-130 (Uncoordinated protein 130) Caenorhabditis elegans anatomical structure morphogenesis [GO:0009653]; axon extension involved in axon guidance [GO:0048846]; cell differentiation [GO:0030154]; embryo development ending in birth or egg hatching [GO:0009792]; maintenance of protein location [GO:0045185]; negative regulation of transcription by RNA polymerase II [GO:0000122]; nematode male tail tip morphogenesis [GO:0045138]; nervous system development [GO:0007399]; regulation of mesodermal cell fate specification [GO:0042661]; regulation of transcription by RNA polymerase II [GO:0006357] GO:0000122; GO:0000977; GO:0000978; GO:0000981; GO:0003700; GO:0003714; GO:0005634; GO:0006357; GO:0007399; GO:0009653; GO:0009792; GO:0030154; GO:0042661; GO:0045138; GO:0045185; GO:0048846 38046 FUN_025326 78 0 0 0 11 NA NA NA NA NA NA NA 38047 FUN_025321 0 0 19 0 34 NA NA NA NA NA NA NA 38048 FUN_025322 585 297 184 602 701 NA NA NA NA NA NA NA 38049 FUN_025323 6533 4496 2855 3442 2530 NA NA NA NA NA NA NA 38050 FUN_001688 431 673 127 652 349 NA NA NA NA NA NA NA 38051 FUN_030090 8 0 0 2 59 NA NA NA NA NA NA NA 38052 FUN_030092 0 0 0 0 29 NA NA NA NA NA NA NA 38053 FUN_030093 0 0 0 21 0 NA NA NA NA NA NA NA 38054 FUN_044365 1 0 4 7 4 NA NA NA NA NA NA NA 38055 FUN_001808 196 0 9 14 36 ntLink_6:16374988-16387139 B8V7P3 4.48e-35 Putative carbonic anhydrase (EC 4.2.1.1) (Carbonate dehydratase) Acropora millepora (Staghorn coral) (Heteropora millepora) NA GO:0004089; GO:0005576; GO:0008270 38056 FUN_001802 1350 1719 931 1618 926 NA NA NA NA NA NA NA 38057 FUN_001801 1047 1868 683 936 584 NA NA NA NA NA NA NA 38058 FUN_001800 27 15 0 42 0 NA NA NA NA NA NA NA 38059 FUN_001807 12 0 0 0 0 NA NA NA NA NA NA NA 38060 FUN_001804 1264 2520 942 1839 1108 NA NA NA NA NA NA NA 38061 FUN_035570 0 0 0 0 9 NA NA NA NA NA NA NA 38062 FUN_035572 290 122 198 405 662 NA NA NA NA NA NA NA 38063 FUN_035573 68 65 35 103 68 ptg000025l:9280961-9282696 Q96JB1 2.46e-54 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 38064 FUN_035573 68 65 35 103 68 ptg000025l:9280961-9282696 Q96JB1 4.45e-22 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 38065 FUN_035574 110 53 33 205 198 NA NA NA NA NA NA NA 38066 FUN_035575 190 146 164 208 141 NA NA NA NA NA NA NA 38067 FUN_035576 176 45 65 88 68 ptg000025l:9337928-9345199 Q96JB1 1.31e-51 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 38068 FUN_035576 176 45 65 88 68 ptg000025l:9337928-9345199 Q96JB1 2.85e-27 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 38069 FUN_035576 176 45 65 88 68 ptg000025l:9337928-9345199 Q96JB1 2.85e-27 Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8) Homo sapiens (Human) cilium-dependent cell motility [GO:0060285]; microtubule-based movement [GO:0007018]; outer dynein arm assembly [GO:0036158] GO:0003777; GO:0005524; GO:0005858; GO:0005874; GO:0005930; GO:0007018; GO:0008569; GO:0030286; GO:0036126; GO:0036157; GO:0036158; GO:0045505; GO:0051959; GO:0060285 38070 FUN_035577 1000 1043 6 1373 755 NA NA NA NA NA NA NA 38071 FUN_035578 665 343 0 412 222 NA NA NA NA NA NA NA 38072 FUN_035579 131 90 0 203 43 NA NA NA NA NA NA NA 38073 FUN_036001 1347 853 548 492 470 NA NA NA NA NA NA NA 38074 FUN_036003 3808 2998 1372 1611 1368 NA NA NA NA NA NA NA 38075 FUN_036002 481 340 294 220 398 ptg000025l:14371428-14373700 O16099 4.54e-134 Maltase 2 (EC 3.2.1.20) Drosophila virilis (Fruit fly) NA GO:0032450 38076 FUN_031057 404 372 204 322 159 NA NA NA NA NA NA NA 38077 FUN_031056 2218 1145 929 1857 2092 NA NA NA NA NA NA NA 38078 FUN_031055 124 74 106 95 34 NA NA NA NA NA NA NA 38079 FUN_031054 5961 6761 4298 11006 9229 ptg000023l:16768816-16785078 Q8CIB5 3.48e-29 Fermitin family homolog 2 (Kindlin-2) (Pleckstrin homology domain-containing family C member 1) Mus musculus (Mouse) adherens junction maintenance [GO:0034334]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; limb development [GO:0060173]; negative regulation of cell death [GO:0060548]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of vascular permeability [GO:0043116]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of integrin activation [GO:0033625]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; protein localization to cell junction [GO:1902414]; protein localization to membrane [GO:0072657]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0001725; GO:0003779; GO:0005178; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0005925; GO:0005938; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008360; GO:0009986; GO:0010718; GO:0016055; GO:0019901; GO:0022604; GO:0030054; GO:0030055; GO:0030335; GO:0031234; GO:0031258; GO:0031674; GO:0033622; GO:0033625; GO:0034334; GO:0034446; GO:0034713; GO:0035505; GO:0043116; GO:0043547; GO:0045599; GO:0045669; GO:0046332; GO:0048041; GO:0051015; GO:0051496; GO:0051894; GO:0051897; GO:0060173; GO:0060548; GO:0070374; GO:0072657; GO:1900026; GO:1900182; GO:1902414; GO:1902462; GO:1903691 38080 FUN_031054 5961 6761 4298 11006 9229 ptg000023l:16768816-16785078 Q8CIB5 1.51e-23 Fermitin family homolog 2 (Kindlin-2) (Pleckstrin homology domain-containing family C member 1) Mus musculus (Mouse) adherens junction maintenance [GO:0034334]; cell adhesion [GO:0007155]; cell-matrix adhesion [GO:0007160]; focal adhesion assembly [GO:0048041]; integrin activation [GO:0033622]; integrin-mediated signaling pathway [GO:0007229]; limb development [GO:0060173]; negative regulation of cell death [GO:0060548]; negative regulation of fat cell differentiation [GO:0045599]; negative regulation of vascular permeability [GO:0043116]; positive regulation of cell migration [GO:0030335]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of GTPase activity [GO:0043547]; positive regulation of integrin activation [GO:0033625]; positive regulation of mesenchymal stem cell proliferation [GO:1902462]; positive regulation of myosin light chain kinase activity [GO:0035505]; positive regulation of osteoblast differentiation [GO:0045669]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of wound healing, spreading of epidermal cells [GO:1903691]; protein localization to cell junction [GO:1902414]; protein localization to membrane [GO:0072657]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360]; substrate adhesion-dependent cell spreading [GO:0034446]; transforming growth factor beta receptor signaling pathway [GO:0007179]; Wnt signaling pathway [GO:0016055] GO:0001725; GO:0003779; GO:0005178; GO:0005547; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0005925; GO:0005938; GO:0007155; GO:0007160; GO:0007179; GO:0007229; GO:0008360; GO:0009986; GO:0010718; GO:0016055; GO:0019901; GO:0022604; GO:0030054; GO:0030055; GO:0030335; GO:0031234; GO:0031258; GO:0031674; GO:0033622; GO:0033625; GO:0034334; GO:0034446; GO:0034713; GO:0035505; GO:0043116; GO:0043547; GO:0045599; GO:0045669; GO:0046332; GO:0048041; GO:0051015; GO:0051496; GO:0051894; GO:0051897; GO:0060173; GO:0060548; GO:0070374; GO:0072657; GO:1900026; GO:1900182; GO:1902414; GO:1902462; GO:1903691 38081 FUN_036009 22 20 0 6 0 NA NA NA NA NA NA NA 38082 FUN_036008 109 16 155 65 111 ptg000025l:14426218-14429714 Q9QZ85 1.42e-34 Interferon-inducible GTPase 1 (EC 3.6.5.-) Mus musculus (Mouse) cellular response to interferon-beta [GO:0035458]; cytokine-mediated signaling pathway [GO:0019221]; defense response [GO:0006952]; defense response to Gram-negative bacterium [GO:0050829]; defense response to protozoan [GO:0042832]; innate immune response [GO:0045087]; regulation of autophagy [GO:0010506]; response to bacterium [GO:0009617] GO:0003924; GO:0005525; GO:0005737; GO:0005789; GO:0006952; GO:0009617; GO:0010506; GO:0019003; GO:0019221; GO:0020005; GO:0031965; GO:0032580; GO:0035458; GO:0042802; GO:0042832; GO:0045087; GO:0050829 38083 FUN_039604 12 12 7 32 43 NA NA NA NA NA NA NA 38084 FUN_039605 0 14 0 9 10 NA NA NA NA NA NA NA 38085 FUN_039602 14 18 10 0 12 NA NA NA NA NA NA NA 38086 FUN_007329 10 0 0 4 34 NA NA NA NA NA NA NA 38087 FUN_021951 67 5 0 15 0 NA NA NA NA NA NA NA 38088 FUN_021950 24 5 0 17 14 NA NA NA NA NA NA NA 38089 FUN_025976 3393 2119 1193 2712 1138 NA NA NA NA NA NA NA 38090 FUN_006051 12 21 15 0 6 NA NA NA NA NA NA NA 38091 FUN_006053 0 0 15 0 0 NA NA NA NA NA NA NA 38092 FUN_006052 3 5 7 0 0 NA NA NA NA NA NA NA 38093 FUN_006057 140 49 39 110 27 NA NA NA NA NA NA NA 38094 FUN_006059 8 16 10 0 7 NA NA NA NA NA NA NA 38095 FUN_006058 0 0 0 0 10 NA NA NA NA NA NA NA 38096 FUN_018529 1092 753 337 1187 1196 NA NA NA NA NA NA NA 38097 FUN_037068 159 0 0 1 3 NA NA NA NA NA NA NA 38098 FUN_037069 32 0 0 0 0 NA NA NA NA NA NA NA 38099 FUN_037060 2292 1729 1506 1854 1642 NA NA NA NA NA NA NA 38100 FUN_018522 2446 1959 1042 2811 2432 NA NA NA NA NA NA NA 38101 FUN_037062 690 427 469 560 637 NA NA NA NA NA NA NA 38102 FUN_037063 892 199 478 1147 472 NA NA NA NA NA NA NA 38103 FUN_037064 2440 2518 979 2216 1684 NA NA NA NA NA NA NA 38104 FUN_037065 92 8 28 42 174 NA NA NA NA NA NA NA 38105 FUN_037066 18 0 0 0 80 NA NA NA NA NA NA NA 38106 FUN_037067 89 0 0 33 66 ptg000026l:5211111-5265627 P08548 3.13e-35 LINE-1 reverse transcriptase homolog (EC 2.7.7.49) Nycticebus coucang (Slow loris) NA GO:0003964; GO:0046872 38107 FUN_006589 42 11 11 55 49 NA NA NA NA NA NA NA 38108 FUN_006588 10 45 67 26 0 NA NA NA NA NA NA NA 38109 FUN_006583 23 0 0 0 5 NA NA NA NA NA NA NA 38110 FUN_006582 948 1413 657 4345 2542 NA NA NA NA NA NA NA 38111 FUN_006581 3080 3652 2104 12785 8426 NA NA NA NA NA NA NA 38112 FUN_006580 879 824 632 2199 2259 NA NA NA NA NA NA NA 38113 FUN_006587 0 0 12 0 0 NA NA NA NA NA NA NA 38114 FUN_006586 34 0 53 47 30 NA NA NA NA NA NA NA 38115 FUN_006585 0 0 11 9 6 NA NA NA NA NA NA NA 38116 FUN_006584 22 36 39 11 80 NA NA NA NA NA NA NA 38117 FUN_032650 0 0 0 0 8 NA NA NA NA NA NA NA 38118 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 5.24e-68 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38119 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 1.83e-50 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38120 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 2.01e-50 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38121 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 3.75e-49 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38122 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 3.78e-48 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38123 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 4.37e-44 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38124 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 1.26e-39 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38125 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 3.86e-33 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38126 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 1.57e-28 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38127 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 1.83e-27 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38128 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 4.14e-26 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38129 FUN_032651 2334 690 286 947 359 ptg000023l:34529981-34535786 P98133 2.83e-24 Fibrillin-1 (MP340) [Cleaved into: Asprosin] Bos taurus (Bovine) activation of protein kinase A activity [GO:0034199]; anatomical structure morphogenesis [GO:0009653]; glucose homeostasis [GO:0042593]; glucose metabolic process [GO:0006006]; protein kinase A signaling [GO:0010737] GO:0001527; GO:0005179; GO:0005201; GO:0005509; GO:0005576; GO:0005615; GO:0006006; GO:0008201; GO:0009653; GO:0010737; GO:0031012; GO:0034199; GO:0042593 38130 FUN_032652 1399 743 1518 1199 840 NA NA NA NA NA NA NA 38131 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 5.47e-74 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38132 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 7.51e-72 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38133 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 1.24e-59 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38134 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 7.25e-45 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38135 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 7.14e-26 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38136 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 3.05e-24 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38137 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 1.02e-22 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38138 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 1.63e-22 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38139 FUN_032653 2397 1261 946 1552 817 ptg000023l:34565271-34571367 Q8N2S1 2.29e-21 Latent-transforming growth factor beta-binding protein 4 (LTBP-4) Homo sapiens (Human) elastic fiber assembly [GO:0048251]; hormone secretion [GO:0046879]; protein folding [GO:0006457]; regulation of cell growth [GO:0001558]; regulation of transforming growth factor beta receptor signaling pathway [GO:0017015]; transforming growth factor beta receptor signaling pathway [GO:0007179] GO:0001527; GO:0001558; GO:0005024; GO:0005178; GO:0005509; GO:0005539; GO:0005576; GO:0005615; GO:0006457; GO:0007179; GO:0017015; GO:0031012; GO:0046879; GO:0048251; GO:0050431; GO:0062023 38140 FUN_032654 161 58 35 0 38 NA NA NA NA NA NA NA 38141 FUN_032655 64 59 76 44 107 NA NA NA NA NA NA NA 38142 FUN_032656 471 145 240 12 27 NA NA NA NA NA NA NA 38143 FUN_032657 118 71 24 0 0 NA NA NA NA NA NA NA 38144 FUN_008574 0 0 0 0 7 NA NA NA NA NA NA NA 38145 FUN_008575 0 0 0 8 22 NA NA NA NA NA NA NA 38146 FUN_006514 402 78 20 543 148 ptg000001l:13436406-13443358 Q7RTR2 3.66e-74 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38147 FUN_006514 402 78 20 543 148 ptg000001l:13436406-13443358 Q7RTR2 3.69e-73 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38148 FUN_006514 402 78 20 543 148 ptg000001l:13436406-13443358 Q7RTR2 2.75e-70 NLR family CARD domain-containing protein 3 (CARD15-like protein) (Caterpiller protein 16.2) (CLR16.2) (NACHT, LRR and CARD domains-containing protein 3) (Nucleotide-binding oligomerization domain protein 3) Homo sapiens (Human) I-kappaB kinase/NF-kappaB signaling [GO:0007249]; intracellular signal transduction [GO:0035556]; negative regulation of cytokine production involved in inflammatory response [GO:1900016]; negative regulation of epithelial cell proliferation [GO:0050680]; negative regulation of fibroblast proliferation [GO:0048147]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of inflammatory response [GO:0050728]; negative regulation of innate immune response [GO:0045824]; negative regulation of interferon-alpha production [GO:0032687]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of interleukin-6 production [GO:0032715]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; negative regulation of NLRP3 inflammasome complex assembly [GO:1900226]; negative regulation of phosphatidylinositol 3-kinase signaling [GO:0014067]; negative regulation of tumor necrosis factor production [GO:0032720]; T cell activation [GO:0042110] GO:0005524; GO:0005737; GO:0005829; GO:0007249; GO:0014067; GO:0032088; GO:0032687; GO:0032688; GO:0032715; GO:0032720; GO:0034451; GO:0035556; GO:0036312; GO:0042110; GO:0043124; GO:0043231; GO:0045824; GO:0048147; GO:0048471; GO:0050680; GO:0050728; GO:1900016; GO:1900226; GO:1901223 38149 FUN_030878 27 0 12 6 13 NA NA NA NA NA NA NA 38150 FUN_030879 0 0 20 6 124 NA NA NA NA NA NA NA 38151 FUN_030872 46 257 169 305 141 NA NA NA NA NA NA NA 38152 FUN_030873 977 1505 622 1089 711 NA NA NA NA NA NA NA 38153 FUN_030870 0 0 0 10 24 NA NA NA NA NA NA NA 38154 FUN_030871 1025 1994 545 258 186 NA NA NA NA NA NA NA 38155 FUN_030876 1745 1612 1081 964 801 ptg000023l:15982130-15983682 Q96F63 2.5e-24 Coiled-coil domain-containing protein 97 Homo sapiens (Human) NA NA 38156 FUN_030877 13033 10242 9019 7100 3707 NA NA NA NA NA NA NA 38157 FUN_030874 3009 1728 1706 2702 2658 ptg000023l:15925716-15962732 Q9P2D3 2.47e-61 HEAT repeat-containing protein 5B Homo sapiens (Human) endocytosis [GO:0006897]; protein localization [GO:0008104]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005829; GO:0006897; GO:0008104; GO:0015031; GO:0016020; GO:0016607; GO:0030136; GO:0030139; GO:0042147; GO:0043231; GO:0048471 38158 FUN_030874 3009 1728 1706 2702 2658 ptg000023l:15925716-15962732 Q9P2D3 5.78e-28 HEAT repeat-containing protein 5B Homo sapiens (Human) endocytosis [GO:0006897]; protein localization [GO:0008104]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005829; GO:0006897; GO:0008104; GO:0015031; GO:0016020; GO:0016607; GO:0030136; GO:0030139; GO:0042147; GO:0043231; GO:0048471 38159 FUN_030874 3009 1728 1706 2702 2658 ptg000023l:15925716-15962732 Q9P2D3 4.75e-25 HEAT repeat-containing protein 5B Homo sapiens (Human) endocytosis [GO:0006897]; protein localization [GO:0008104]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005829; GO:0006897; GO:0008104; GO:0015031; GO:0016020; GO:0016607; GO:0030136; GO:0030139; GO:0042147; GO:0043231; GO:0048471 38160 FUN_030874 3009 1728 1706 2702 2658 ptg000023l:15925716-15962732 Q9P2D3 5.03e-23 HEAT repeat-containing protein 5B Homo sapiens (Human) endocytosis [GO:0006897]; protein localization [GO:0008104]; protein transport [GO:0015031]; retrograde transport, endosome to Golgi [GO:0042147] GO:0005829; GO:0006897; GO:0008104; GO:0015031; GO:0016020; GO:0016607; GO:0030136; GO:0030139; GO:0042147; GO:0043231; GO:0048471 38161 FUN_030875 1286 1583 806 1475 817 NA NA NA NA NA NA NA 38162 FUN_001586 10 22 100 58 0 ntLink_6:14032810-14035104 Q8IYB1 3.95e-21 Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2) Homo sapiens (Human) NA GO:0016779; GO:0044877; GO:0045296 38163 FUN_001587 2506 2235 1380 2970 2679 NA NA NA NA NA NA NA 38164 FUN_001584 56 61 31 37 0 NA NA NA NA NA NA NA 38165 FUN_004568 6232 3479 2554 6183 6912 ntLink_8:24404768-24414859 O76031 2.49e-32 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial Homo sapiens (Human) ATP metabolic process [GO:0046034]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0005524; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006508; GO:0008270; GO:0009368; GO:0009841; GO:0016504; GO:0016887; GO:0042645; GO:0046034; GO:0046983; GO:0051082; GO:0051603; GO:0140662 38166 FUN_004568 6232 3479 2554 6183 6912 ntLink_8:24404768-24414859 O76031 2.49e-32 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial Homo sapiens (Human) ATP metabolic process [GO:0046034]; proteolysis [GO:0006508]; proteolysis involved in protein catabolic process [GO:0051603] GO:0005524; GO:0005654; GO:0005739; GO:0005743; GO:0005759; GO:0005829; GO:0006508; GO:0008270; GO:0009368; GO:0009841; GO:0016504; GO:0016887; GO:0042645; GO:0046034; GO:0046983; GO:0051082; GO:0051603; GO:0140662 38167 FUN_001582 1689 1841 1833 1324 1326 NA NA NA NA NA NA NA 38168 FUN_001583 1458 1293 732 1575 1387 NA NA NA NA NA NA NA 38169 FUN_001580 15 20 30 34 10 NA NA NA NA NA NA NA 38170 FUN_001581 624 317 383 666 354 ntLink_6:13983935-13996463 O43301 6.13e-132 Heat shock 70 kDa protein 12A Homo sapiens (Human) NA GO:0005524; GO:0005634; GO:0005737; GO:0070062 38171 FUN_001581 624 317 383 666 354 ntLink_6:13983935-13996463 O43301 4.04e-39 Heat shock 70 kDa protein 12A Homo sapiens (Human) NA GO:0005524; GO:0005634; GO:0005737; GO:0070062 38172 FUN_004563 13 0 6 0 0 NA NA NA NA NA NA NA 38173 FUN_004562 6616 4617 3528 6239 4990 NA NA NA NA NA NA NA 38174 FUN_004561 633 955 306 541 581 NA NA NA NA NA NA NA 38175 FUN_004560 1512 933 1325 920 555 NA NA NA NA NA NA NA 38176 FUN_004567 2572 1776 1156 1915 1435 NA NA NA NA NA NA NA 38177 FUN_004566 5327 3842 3544 5324 5837 NA NA NA NA NA NA NA 38178 FUN_004565 3238 2129 1813 2777 2844 NA NA NA NA NA NA NA 38179 FUN_004564 2881 1932 1643 2658 2851 NA NA NA NA NA NA NA 38180 FUN_006879 0 249 38 33 40 NA NA NA NA NA NA NA 38181 FUN_001058 11206 21817 51893 12168 8477 NA NA NA NA NA NA NA 38182 FUN_001059 1991 1255 180 494 1305 ntLink_6:8020976-8024803 P57093 1.51e-70 Phytanoyl-CoA dioxygenase, peroxisomal (EC 1.14.11.18) (Phytanic acid oxidase) (Phytanoyl-CoA alpha-hydroxylase) (PhyH) Rattus norvegicus (Rat) 2-oxobutyrate catabolic process [GO:0019606]; 2-oxoglutarate metabolic process [GO:0006103]; fatty acid alpha-oxidation [GO:0001561]; isoprenoid metabolic process [GO:0006720]; methyl-branched fatty acid metabolic process [GO:0097089] GO:0001561; GO:0003824; GO:0005739; GO:0005777; GO:0006103; GO:0006720; GO:0008198; GO:0019606; GO:0031406; GO:0031418; GO:0048244; GO:0097089; GO:0097731 38183 FUN_016516 39 88 34 128 88 ptg000011l:4244706-4251664 Q96AY4 4.88e-172 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38184 FUN_016516 39 88 34 128 88 ptg000011l:4244706-4251664 Q96AY4 7.28e-153 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38185 FUN_016516 39 88 34 128 88 ptg000011l:4244706-4251664 Q96AY4 7.42e-152 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38186 FUN_016516 39 88 34 128 88 ptg000011l:4244706-4251664 Q96AY4 4.4e-151 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38187 FUN_016516 39 88 34 128 88 ptg000011l:4244706-4251664 Q96AY4 5.82e-64 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38188 FUN_016516 39 88 34 128 88 ptg000011l:4244706-4251664 Q96AY4 4.3e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38189 FUN_001050 162 86 128 199 251 NA NA NA NA NA NA NA 38190 FUN_001051 2488 1715 1424 2509 1796 NA NA NA NA NA NA NA 38191 FUN_001052 21 19 0 28 14 NA NA NA NA NA NA NA 38192 FUN_001053 5317 5250 3090 7041 6809 ntLink_6:7920315-7944103 Q7ZT42 3.93e-31 Staphylococcal nuclease domain-containing protein 1 (100 kDa coactivator) (4SNc-Tudor domain protein) (p100 co-activator) Danio rerio (Zebrafish) (Brachydanio rerio) mRNA catabolic process [GO:0006402]; RNA-mediated gene silencing [GO:0031047] GO:0003723; GO:0004518; GO:0005634; GO:0005737; GO:0005829; GO:0006402; GO:0016442; GO:0031047 38193 FUN_001054 3063 2218 1213 2942 1502 NA NA NA NA NA NA NA 38194 FUN_001055 187 48 25 162 57 NA NA NA NA NA NA NA 38195 FUN_001056 384 83 219 202 137 NA NA NA NA NA NA NA 38196 FUN_001057 66675 50639 16398 30794 21015 NA NA NA NA NA NA NA 38197 FUN_033521 0 0 13 0 0 NA NA NA NA NA NA NA 38198 FUN_033525 0 13 0 0 3 NA NA NA NA NA NA NA 38199 FUN_033524 0 33 0 13 46 NA NA NA NA NA NA NA 38200 FUN_033529 18 138 0 0 0 NA NA NA NA NA NA NA 38201 FUN_004697 883 1172 354 773 563 NA NA NA NA NA NA NA 38202 FUN_004696 92 70 121 95 243 NA NA NA NA NA NA NA 38203 FUN_004691 15317 10224 5359 10948 6717 NA NA NA NA NA NA NA 38204 FUN_004690 7250 4922 4501 8039 7039 NA NA NA NA NA NA NA 38205 FUN_004693 275 86 35 180 305 NA NA NA NA NA NA NA 38206 FUN_004692 115 88 66 74 43 NA NA NA NA NA NA NA 38207 FUN_002590 1 15 304 14 8 NA NA NA NA NA NA NA 38208 FUN_002591 47 0 100 50 66 NA NA NA NA NA NA NA 38209 FUN_002592 69 97 154 7 102 NA NA NA NA NA NA NA 38210 FUN_002593 75 385 718 22 66 NA NA NA NA NA NA NA 38211 FUN_002594 25 0 33 0 0 NA NA NA NA NA NA NA 38212 FUN_002595 18 18 10 10 10 NA NA NA NA NA NA NA 38213 FUN_002596 29 126 57 56 120 NA NA NA NA NA NA NA 38214 FUN_002597 0 0 22 0 84 NA NA NA NA NA NA NA 38215 FUN_002598 0 0 0 0 9 NA NA NA NA NA NA NA 38216 FUN_035969 943 807 507 612 622 ptg000025l:14064819-14072901 Q6ZM19 1.23e-22 Eukaryotic translation initiation factor 6 (eIF-6) Danio rerio (Zebrafish) (Brachydanio rerio) assembly of large subunit precursor of preribosome [GO:1902626]; cytosolic ribosome assembly [GO:0042256]; maturation of 5.8S rRNA [GO:0000460]; maturation of LSU-rRNA [GO:0000470]; ribosomal subunit export from nucleus [GO:0000054] GO:0000054; GO:0000460; GO:0000470; GO:0003743; GO:0005730; GO:0005829; GO:0030687; GO:0042256; GO:0043022; GO:0043023; GO:1902626 38217 FUN_035968 270 338 216 267 152 ptg000025l:14053379-14054689 A5PJK1 4.66e-26 Transmembrane protein with metallophosphoesterase domain (EC 3.1.-.-) Bos taurus (Bovine) NA GO:0016020; GO:0016787; GO:0046872 38218 FUN_035963 12 0 25 18 26 NA NA NA NA NA NA NA 38219 FUN_035962 4784 2415 2347 4304 3986 ptg000025l:13983706-14019192 Q9GYZ0 5.9e-24 Kinesin-like protein KIF15 (Kinesin-related protein KRP180) Strongylocentrotus purpuratus (Purple sea urchin) microtubule-based movement [GO:0007018]; regulation of mitotic spindle assembly [GO:1901673] GO:0003777; GO:0005524; GO:0005737; GO:0005819; GO:0005871; GO:0005874; GO:0007018; GO:0008017; GO:0016887; GO:1901673 38220 FUN_035961 4 3 30 0 6 NA NA NA NA NA NA NA 38221 FUN_035967 6 101 33 30 16 NA NA NA NA NA NA NA 38222 FUN_035965 476 259 115 431 809 NA NA NA NA NA NA NA 38223 FUN_035964 66 0 19 11 38 ptg000025l:14035572-14037118 Q76KP1 9.28e-34 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (NGalNAc-T1) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4) Homo sapiens (Human) NA GO:0008376; GO:0032580; GO:0033842 38224 FUN_023964 87 60 13 149 247 NA NA NA NA NA NA NA 38225 FUN_040003 0 1 0 11 19 NA NA NA NA NA NA NA 38226 FUN_023965 190 68 95 160 218 NA NA NA NA NA NA NA 38227 FUN_023966 17 31 32 61 38 NA NA NA NA NA NA NA 38228 FUN_031605 2156 2240 878 1333 1125 NA NA NA NA NA NA NA 38229 FUN_031602 45 84 23 30 33 NA NA NA NA NA NA NA 38230 FUN_031603 17 12 17 31 87 NA NA NA NA NA NA NA 38231 FUN_023962 3095 2191 1752 5360 4914 NA NA NA NA NA NA NA 38232 FUN_023963 100 104 49 66 139 NA NA NA NA NA NA NA 38233 FUN_012469 660 442 207 598 315 ptg000008l:9204606-9205869 Q9XTR8 1.14e-27 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 38234 FUN_012468 289 298 148 406 437 ptg000008l:9188457-9189708 Q9XTR8 7.11e-34 Lipase ZK262.3 (EC 3.1.1.-) Caenorhabditis elegans lipid catabolic process [GO:0016042] GO:0005576; GO:0016042; GO:0016787 38235 FUN_012465 2174 3375 1526 1949 1356 NA NA NA NA NA NA NA 38236 FUN_012464 0 7 18 12 0 NA NA NA NA NA NA NA 38237 FUN_012467 1085 620 603 839 809 NA NA NA NA NA NA NA 38238 FUN_012466 2954 1484 1269 1157 609 ptg000008l:9162265-9170371 B0S6T2 7.14e-22 Solute carrier family 15 member 2 (Peptide transporter 2) (PEPT2) Danio rerio (Zebrafish) (Brachydanio rerio) dipeptide import across plasma membrane [GO:0140206]; innate immune response [GO:0045087]; peptidoglycan transport [GO:0015835]; protein transport [GO:0015031]; regulation of nucleotide-binding oligomerization domain containing signaling pathway [GO:0070424]; response to yeast [GO:0001878]; transmembrane transport [GO:0055085] GO:0001878; GO:0005886; GO:0015031; GO:0015293; GO:0015835; GO:0016020; GO:0022857; GO:0045087; GO:0055085; GO:0070424; GO:0071916; GO:0140206 38239 FUN_012461 962 598 715 855 510 ptg000008l:9138144-9144687 Q0EEE2 8.05e-35 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 38240 FUN_012461 962 598 715 855 510 ptg000008l:9138144-9144687 Q0EEE2 1.95e-21 Patched domain-containing protein 3 (RND-type protein RNDEu-3) Mus musculus (Mouse) NA GO:0005783; GO:0005789; GO:0005886; GO:0016020; GO:0097225 38241 FUN_012460 4 71 76 11 21 NA NA NA NA NA NA NA 38242 FUN_012463 808 499 224 1028 198 NA NA NA NA NA NA NA 38243 FUN_012462 20 12 41 17 27 NA NA NA NA NA NA NA 38244 FUN_006873 90 149 58 86 61 NA NA NA NA NA NA NA 38245 FUN_006872 793 638 385 639 419 NA NA NA NA NA NA NA 38246 FUN_006871 966 291 1663 6071 2679 NA NA NA NA NA NA NA 38247 FUN_006870 407 369 638 4332 2114 NA NA NA NA NA NA NA 38248 FUN_006877 917 525 235 484 358 NA NA NA NA NA NA NA 38249 FUN_016518 144 64 22 134 73 ptg000011l:4269032-4276173 Q96AY4 2.02e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38250 FUN_016518 144 64 22 134 73 ptg000011l:4269032-4276173 Q96AY4 1.49e-138 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38251 FUN_016518 144 64 22 134 73 ptg000011l:4269032-4276173 Q96AY4 4.53e-110 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38252 FUN_016518 144 64 22 134 73 ptg000011l:4269032-4276173 Q96AY4 1.01e-96 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38253 FUN_016518 144 64 22 134 73 ptg000011l:4269032-4276173 Q96AY4 1.32e-91 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38254 FUN_016518 144 64 22 134 73 ptg000011l:4269032-4276173 Q96AY4 7.81e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38255 FUN_006875 714 57 164 445 1600 NA NA NA NA NA NA NA 38256 FUN_006874 39 169 45 87 97 NA NA NA NA NA NA NA 38257 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 2.69e-173 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38258 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.41e-171 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38259 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 3.75e-169 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38260 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 5.44e-166 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38261 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 8.52e-154 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38262 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 4.79e-146 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38263 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.48e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38264 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.48e-140 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38265 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 2.31e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38266 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 2.31e-108 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38267 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 7.12e-40 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38268 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.2e-33 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38269 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 8.8e-30 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38270 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 5.9e-29 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38271 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.71e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38272 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 3.89e-28 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38273 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 3.8e-26 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38274 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.56e-25 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38275 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 3.35e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38276 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 5.24e-24 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38277 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.3e-23 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38278 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 1.01e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38279 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 4.81e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38280 FUN_016514 51 88 58 158 80 ptg000011l:4216927-4222401 Q96AY4 7.45e-22 Tetratricopeptide repeat protein 28 (TPR repeat protein 28) (TPR repeat-containing big gene cloned at Keio) Homo sapiens (Human) cell cycle [GO:0007049]; cell division [GO:0051301]; regulation of mitotic cell cycle [GO:0007346] GO:0000922; GO:0005737; GO:0005815; GO:0007049; GO:0007346; GO:0019900; GO:0030496; GO:0051301 38281 FUN_006878 1 47 34 41 82 NA NA NA NA NA NA NA 38282 FUN_016510 5067 3479 1318 3194 1496 NA NA NA NA NA NA NA 38283 FUN_016512 335 496 350 113 482 NA NA NA NA NA NA NA 38284 FUN_017853 109 119 92 116 93 ptg000012l:1118212-1119208 Q9BRF8 7.11e-39 Serine/threonine-protein phosphatase CPPED1 (EC 3.1.3.16) (Calcineurin-like phosphoesterase domain-containing protein 1) (Complete S-transactivated protein 1) Homo sapiens (Human) NA GO:0005576; GO:0005829; GO:0005886; GO:0017018; GO:0035578; GO:0046872 38285 FUN_009372 34 18 0 18 78 NA NA NA NA NA NA NA